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                    <text>Volume 21, Number 5

I

and Biomedical Scientist

Study lryDr. Lau,renceBone demonstratesneed
for aggressivesurgeryin trauma cases

Lace Winter 1988

�Dear Alumni, Alumnae and Friends:

STAFF
EXECUTIVEEDITOR
UNIVERSITY PUBLICATIONS
Robert T. Marlett
BUFFALOPHYSICIAN EDITOR
Connie Oswald Stofko
ART DIRECTOR
Alan J. Kegler
PHOTOGRAPHY
DouglasLevere
EdNowak
Ian Redinbaugh
Simon Tong

ADVISORYBOARD
Dr. John Naughton, Chairman
Dr. Harold Brody
Mr. Kevin Craig
Ms. Karen Oryja
Ms. Nancy Olieco
Dr. James Kanski
Ms. Marion Marionowski
Dr. Daniel Morelli
Dr. Charles Paganelli
Mr. James Phillips
Mr. John Pulli
Dr. Robert Scheig
Mr. Mike Shaw
Mr. Steve Shivinsky
Mr. Raul Velasquez
Dr. Mary Voorfiess
Dr. John Wright
Dr. MaggieWright
Dr. Franklin Zeplowit:z
Dr. Joseph Zizzi,Jr.
TEACHINGHOSPITALS
BuffaloGeneral
Children's
Erie County MedicalCenter
Mercy
Millard Fillmore
RoswellPark Memorial Institute
Sisters of Charity
Veterans Administration
Medical Center
Producedlry ihe Divisionof University
Relatumsin associationwith ihe School
of Medicine,State Universityof New
Yorkat Buffalo.
THE BUFFALO PHYSICIAN
(USPS 551-860) Late Winter 1988,
Volume 21, Number 5. Publishedfive
times annually: Late Winter, Spring,
Summer, Fall and Early Winter - by
the School of Medicine, State University of New York at Buffalo, 3435
Main Street, Buffalo, New York
14214. Third class bulk postage paid
at Buffalo, New York. Send address
changes to THE BUFFALOPHYSICIAN, 146 C.F.S. Addition, 3435
Main Street, Buffalo, New York
14214.

Cover Photo: Dr. Lawren ce
Bone,photographedb:,Rob McElroy.

T

he medical school has embarked on its second Institutional
Self-Study in preparation for the accreditation visit by the
Liaison Committee on Medical Education (LCME) Survey
Team scheduled for November of this year. The first self-study was
condurn:d in 1980. We have set an ambitious time-table in that all
committee work is scheduled tO be completed during the first six
months of 1988 so that a final document can be edited and collated
for submission to the LCME by September. Just as was done in 1980,
a large steering committee has been assembled with representation of
University administration, hospital board members and administrators, department chairmen, faculty and students, alumni, practicing
physicians and members of my staff.
In contrast tO 1980 , the established commim:es of the Faculty
Council are serving as the working committee for the various areas to
be reviewed. External representatives have been added to the membership of each committee to ensure that as much communication and
cross-fertilization as possible can be and is facilitated.
When the task is completed this summer, we will have an appreciation of the progress made since 1980, the current status of the
medical education enterprise in Buffalo, and an agenda of tasks to be
accomplished bt::tween now and 1995. These outcomes will be summarized in a future issue of the Physician.
As I had indicated in an earlier letter, the timing for this study is
fortuitous since it comes during the 25th anniversary year of the merger
ofUB with SUNY. The process should be helpful to the life and vigor of
the institution and in preparing us for a successful accreditation visit next
fall.

Sincerely,
John Na ughton , M.D.
Vice Presidentfor Clmrcal Affairs
Dean, School of Medrcine

Medical Alumni

President's Message

I

t gives me a great deal of pleasure to announce that the recipient
of the Stockton Kimball Memorial Award for 1988 will be Dr.
Robert Gale of the University of California at Los Angeles
- UCLA. Dr. Gale is a 1970 graduate of the University at Buffalo
School of Medicine and has distinguished himself in the field of bone
marrow transplantation. His prominent role in leading the American
effort in aiding the Soviet Union after the world's worst nuclear
disaster is, I am sure, well known to all of you. His involvement in this
endeavor as well as his consu lt ant role in other nuclear accident
incidents continues. His timely and info rm ative lecture at the
luncheon will be a highlight of an outstanding program at "Spring
Clinical Day and Reunion Weekend" - May 7, 1988. The morning
scientific program will be devoted to Controversies and Treatment of
AIDS, Breast Cancer, and Coronary Arte r y Disease with national and
local experts . Mark your calenda rs now so that we can welcome as
many of you as possible from around the count ry and the Western
New York area to this program and to your five-yea r reunions.
Your A lu mni Association continues co play a prominent role in
Medical School affairs, with you r President being a member of the
Executive Committee of t he School and a member of the Steering
Committee and Executive Committee of the "Liaison Committee for
Medical Education" - LCME which is self-evaluating the School
prio r to the acc reditation survey in the fall of 1988.
If you have not become an Active or Life Member of the Medical
Alumni Association, please do so now, so that you can help us
continue and expand all the activities I mentioned in the last
Newsletter.

-

Sincerely,
Franklin Zeplowit~, M.D. '58

�BUFFAlD

Volume 21, Number 5

PtIX§l~~

Late Wint er 1988

2

Lead Poisoning. Screening children for lead poisoning should be a
routine part of medical care, Public Health Official urges.

7

Black Monday. One man lost his shirt in the market crash and shot
his stockbroker; others shrugged it off. Why the difference?

8

Premenstrual Syndome. Dr. Uriel Halbreich, head of a new Life~
Cycle Center, finds the term premenstrual changes or PMC more
accurate.

11

Leeches. What do leeches and microsurgery have in common? Plenty
if you ask Dr. Kulwant Bhangoo.

14

Lawrence Bone M.D. Thousands of lives lost following auto
accidents and other causes of severe trauma co uld be saved, this
orthopaedic surgeon has found, if a new surgical approach is adopted.

Departments

Page8

Page 14

17

Research. Unique Roswell case report was the key to a breakthrough
genetic study published recently by British scientists.

21

Medical School News. The Buffalo General Hospital, a major UB
teaching hospital, is establishing the State's second heart transplant
center.

30

Classnotes . Two Med School graduates are the co~founders of the
Comprehensive Headache Center at The Germantown Hospital and
Medical Center in Philadelphia. News of the classes.

35

Hospital News. The Batavia Veterans Administration
Center becomes UB's ninth affiliated hospital.

36

Deaths.

Medical

�POISONING
Samephysicianssay it isn't a problemin theirareas
becausethey haven'tseena casein 20 years. But many
childrenshowno overtsymptoms,healthofficialwarns

BY CONNIE OSW ALO STOFKO

S

creening children for lead poisoning should be a routine part of
medical care, recommends Jane S.
Lin-Fu, M.D., whose research was instrumental in the federal legislation that
banned lead from household paint.
Some physicians say that lead poisoning isn't a problem in their area because
they haven't seen a case in 20 years. But
many children with lead poisoning show
no overt symptoms, Lin-Fu cautioned.
Even when there are overt symptoms,
they're so vague that they're often misdiagnosed, she noted. It's nearly impossible to detect lead poisoning without a
blood test.
It's also a myth that lead poisoning
affects only inner-city children, she
added. It's a ''Yuppie" problem, too,
especially for those who move into older
homes and do the renovat ion themselves.
in-Fu is acting chief of the genetics
services branch of the Health Resources and Services Administration.
That's pa rt of the U.S. Public Health
Services.
She recently gave a lecture sponsored
by the Research Center for Child ren and
Youth, one of UB's eight organized
research centers.
In the United States, Lin-Fu estimates,
tens of thousands of children are affected
by this condition, which can lead to
retardation and even death. While it can
affect adults, children are more prone to
lead poisoning for many reasons, including the fact that child ren have greate r

L

Late Winter '8 8

intestinal absorption and retention and
their organs are more immature.
Routine screening is important because
there's convincing evidence that undue
lead absorpt ion in early life may be associated with neuropsychological
deficiencies and behavioral disorders, leading to learning disabilities. This happens
before there are any overt symptoms,
Lin-Fu said.
And even when it gets to the point of
overt symptoms, there's no guarantee
that lead poisoning will be detected
without a blood test, she noted.
The symptoms are vague: irritability,
refusal to play, apathy, poor appetite,
occas ional vom iting, sleep disturbances,
stomach aches, and constipation.
Lin-F u , who has three children of her
own, noted that these symptoms are
common to "no rm al" children.
"You have to be very astute to pick it
up as lead poisoning," she said. "You
can't rely on signs and symptoms to
diagnose it."
Those are the relatively early symptoms, she said. If nothing is done, the
child can experience developmental
delays and regressions . A child may stop
making sentences or stop jumping.
The child may have protracted vomiting, ataxia, or convulsions, or even die.
Even when the condition gets to the
convulsions stage, lead poisoning can be
misdiagnosed. A two-year-old with lead
poisoning was operated on twice because
it was thought she had a brain tumor,
Lin-Fu said. The test for lead poisoning,
eryth r ocyte protoporphyrin
(E P), is

cheap, she said, and has the added
advantage of picking up iron deficiencies.Just a small amount of blood from a
finger prick is needed.
The equipment, a hematofluorometer, costs about $4,000 and is cheap
enough to be purchased by a clinic, she
pointed out.
Because it gives an instantaneous d igital readout, follow-up tests can be performed while the child is still in the
office. There's no loss of follow-up.
But how much lead is too much lead?
The answer has been changing in the last
two decades, Lin-Fu noted.
Unlike calcium, zinc, or iron, which
the body needs in certain amounts, the
body doesn't need any lead at all. But
researchers forgot that fact when they
tried to define "normal" lead levels, she
said.
"They started studying the 'normal'
population, not realizing that the 'no rmal' population was contaminated."
In 1970, the accepted level of lead in
the blood was a whopping 60 micrograms . Lin -Fu fought a tough battle to
get it lowered to 40 micrograms.
Today, even 40 is considered much
too high, she noted . Various agencies in
the past few years have recommended
25, 20, or even 10.S.
Lin-Fu said she doesn't know whether
the accepted limit should be dropped to
zero . She noted that people in the Himalayas were tested and even they had 3
micrograms of lead. There is disagreement ove r when treatment should begin ,
she noted. The treatment is painful. It

Buffalo Physician and Biomedical Scientist

�can also be dangerous because it removes
vital zinc and forces some of the lead to
the brain.
Even if the physician decides not to
treat the condition, it's important to
look for lead in the environment, Lin-Fu
said.

3

A major culprit is lead paint on walls.
Th e ban on lead in household paint
didn't go into effect until 1978, she
noted.
Lead abatement must be done carefully. If done improperly, scraping the
paint off the walls can actually do more
harm because it creates fine particles
which can be more easily absorbed, she
explained. Once the particles get into the
rugs and curtains, a regular vacuum
cleaner won't pick them up.
During lead abatement, it's important
to get everyone out of the house, remove
all belongings that can be moved, cover
everything that remains, and clean up
carefully.
Disposal of the lead is a problem, too.
She noted that when people remove lead
from their houses, they just put it in
plastic bags and take it to a dump. But it
doesn't change into some other substance when burned; the problem is just
recycled.
ead paint isn't the only source of
lead poisoning, Lin-Fu said.
"We pay a price" for living in this
modern world, she said. "Lead is in the
air you breathe, the food you eat, and
the water you drink."
The elevated lead levels of most children aren't caused by eating paint chips,
as was once thought, Lin-Fu pointed
out. Small children put their hands in
their mouths a lot and ingest the lead
from household dust and soil they pick
up while playing.
Another source of lead is water that
sits overnight in pipes soldered with
lead.
"New houses, including the one I
moved into two years ago, have copper
pipes with lead solde r ," she noted. People are advised to run their water each
morning to get rid of the stagnant water.

L

Buffalo Physician and Biomedical Scientist

Late Winter '88

�4
Othe r sources of lead include industrial emissions, burning at city dumps,
storage batteries, ammunition, improperly glazed dinnerware, burning old wood
that's covered with lead paint, arts and
crafts supplies, colo red ink for newspaper, smoking, some alcohol, and cosmetics such as Grecian Formula.
Some folk remedies contain lead as
well.
"Health care providers must remem-

ber this is a land of immigrants," Lin-Fu
said, and that people bring these remedies with them.
A couple of sources of lead are on the
decrease. Leaded gasoline has been
banned for newer cars. In the four yea rs
since the ban, blood lead levels have
decreased 30 per cent. Lin-Fu is convinced the ban should get the credit.
"Nothing else could explain such a
dramatic drop," she explained.

Lead solder for food cans is also on
the wane. In 1979, 90 per cent contained
lead solder. In 1986, only 28 per cent
did.
Lead poisoning is still a problem, even
though we've known since early in this
century that it's preventable, Lin-Fu
pointed out.
"Here we are 70 years later still talking about lead poisoning," she remarked.
•

Two UB units working on lead study

T

wo UB units are working together to compare lead levels in the umbilical cords of
newborns to medical and socio-economic
data, with an eye to how that information may be
related to developmental disabilities.
The two units are the interdisciplinary Research
Center for Children and Youth and the Division of
Developmental and Behavioral Neurosciences of
the Department of Neu ro logy in UB's School of
Medicine and Biomedical Sciences.
During pregnancy, lead is mobilized just as calcium is and may go to the fetus, explained David
Shucard, Ph.D., professor of neurology and pediatrics and director o f the Divisio n of Developmental
and Behavioral Neurosciences.
No one knows what levels oflead are toxic, Shucard noted .
The other researchers o n th e project include:
• Janet Shuca rd, instructor in neurology at UB
• Matthew Lanighan, Ph .D., clinical instructo r in
medical technology at UB and assistant director of
public health for the Erie County Public Health
Laboratory
• Robert J . Patterson, M.D., clinica l associate
professor ofGYN-OB at UB and clinical chief in the
depa rtme nt of GYN-0B at Child ren's Hospital
• Robe rt Gu thr ie, Ph.D., M.D., professor emeritus in pediatrics and neurobiology
In February, the researchers expected to finish
collecting abou t 1,200 blood samples from births at
Children's Hospital. The blood is taken routinely

Late Winter '88

for other tests, Shucard noted.
The researchers also collected medical and socioeconomic data from the mothers' and babies' charts .
The informa t ion included the baby's gestational
age, b irt h weight, Apgar scores, sex, and order of
birth in the family.
Information on the mother included hemoglobin
level ( there may be a relationship between lead and
anemia, Shucard explained), any complications during pregnancy, age, education, and where she lives.
Where the women live may show if certa in local
areas have higher lead levels than others, he noted.
Unlike toddlers, the mothers aren't eating paint
chips.
The researchers have been looking for fund ing to
pay salaries of a gr aduate student and clerical help to
analyze the data. State money is available for screening, Shucard noted, but this project doesn't co unt as
screening because there are no existing guidelines o n
what levels oflead are considered high for u mbilical
blood.
T here have been very few stud ies in this count r y
on the lead levels in umb ilical cord blood, Shucard
said . Work is generally done with toddlers, not
newborns.
A large scale study is planned with federa l support. It will include more of the preventive and
socia l aspects of lead poisoning, which are of major
interest to Anthony M. Graziano, Ph.D., and Murray Levine, J.D . , Ph .D., the co-directors of the
Research Ce nter for Child ren and Youth.
•

Buffalo Physician and Biomedical Scientist

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�1

BIACKMONDAY
Someinvestorsshrugged;otherspanicked.Why?
BY CONNIE OSW ALO STOFKO

0

ne man lost his shirt on "Black Monday" and shot
his stockbroker. Other investors lost just as much
-or even more - in October's stock market crash
and simply shrugged it off.
Why ar e there such different reactions to the same event?
It has a lot to do with both the individual's history and the
significance of the loss, explained George Molnar, M.D., associate professor and vice chairman in the Department of Psychiatry at UB.
Molnar has an interest in stress-related disorders. As a psychiatrist with the U.S. Army Reserve, he looks at the concept
of stress and stress reaction to extreme situations.
The stock market crash was a stressful situation and could be
experienced by some individuals in the same way they would
experience other extreme situations, such as a car accident,
combat, or the loss of a parent, Molnar explained.
These situations have different meanings for different people
at different stages in life.

T

he significance of the loss to the individual is an important factor in how the person will react, Molnar said.
Where the loss of $2,000 may break one investor, even a $1
million loss may be dismissed by another as just a "paper loss."
The person's reaction also depends on his vulnerability,
social supports, the intensity of stress, and how he deals with
anger. Alcohol and other drugs can disinhib it behavior, such as
violence, that's normally inhibited, Molnar said.
One case of violence was the incident in Miami where a man
incurred heavy losses and killed his stockbroker.
But, according to newspaper accounts, the man apparently
had a complicated life history, Molnar pointed ou _t. He was in
the government's protected witness program. He may have
been an unbalanced individual, prone to impulsive actions,
particularly precipitated by events such as his sudden loss in
the market.
"So in addition to looking at the immediate stress, he was
probably predisposed to acting this way," he pointed out. "It
didn't come out of the blue."

Buffalo Ph ysic ian and Biomdica l Scientist

Indiffer enc e and homicidal anger are the two extremes,
Molnar said. Many reactions fall in th e middle and can occur
long after the crash or other traumatic event.
Anxiety disorders, depressive disorders, or adjustment disorders are other means of response and reaction to such events.
In some extrem e cases, ther e can be a brief reactive psychosis, Molnar said.
Psychosomatic conditions such as hypertension, peptic
ulcers, migraine headaches, and irritable bowel may also come
into play.
Some people just become irritable, angry, or depress ed and
begin to self-medicate with alcohol. These feelings can add to
ongoing marital conflicts.
Stress over the course of the stock market doesn't affect just
investors. People who work in the market, such as brokers and
secretaries, feel it, too, Molnar pointed out. They find their
jobs are more precarious, and their workdays are filled with
pressure and angry clients. Often their self-esteem rides with
their success in the stock market.
"S everal individual s no doubt committ ed suicide, from what
I read," Molnar said.
Even people who don't have money in the market can feel
anxious and alarmed when hearing news reports about the
economic situation.

S

tress-related conditions are eminently treatable, Molnar
said. If there are no previous complicating disorders, brief
psychotherapy and medication should be sufficient. Treatment
will diminish the severity of or remove symptoms and keep the
condition from getting chronic.
There shouldn't be excessive use of medication, Molnar
pointed out; usually a single agent should be used.
Molnar noted that most people haven't become ill from the
stock market crash.
"The great majority of individuals went about the normal
business of their lives,'' he said. ''They weren't pleased with the
loss of money, even if it was only a paper loss, but they took it
in stride. They accepted it as part of doing business."
•

La tt:

\Vintcr '88

�8

PREMENSTRUAL
CHANGESARETHE
FOCUSOFA NEW
LIFE--CYCLE
CENTER
BY CLARE O'SHEA

0

n two different Friday nights,
Jane goes to parties. On Friday
night numbe r one,Jane and her
boyfriend have three or four drinks and
feel equally tipsy.
The nex t Friday night, they go to
another party and drink the same amount
of alcohol. Jane 's boyfriend is no more
tipsy than he was last week. But Jane is
more impulsive, her concen tration is a
little off, her memory's not as sharp as
usual. This week, Jane is tipsier. She's
also expecting her period.
Such an effect of alcohol on women in
the premenstrual phase is just one of
many possible characteristics of the
condition known as premenstrual syndrome, or PMS.
Uriel Halbreich, psychiatry professor
and director ofbiobehavioral research at
UB, rejects the popular PMS label, however, in favor of PMC, or premenstrual
changes. PMC is the more accurate term,
Halbr eich believes, for a couple of reasons. The term syndrome implies more
than one symptom; it is possible, though,
to have just one change premenstrually.
In addition , research has shown that
positive as well as negative changes can
be associated with the premenstrual
phase .
Lare Winter '88

T

he study of premenstrual changes
as a phenomena is relatively new.
"There has been a tendency in the past
for the problems associated with PMS to
be minimized or simply dismissed by
some physicians," Halbreich said. "Often
the patient's complaints were not taken
seriously or it was implied that he r
symptoms were 'all in her head.' 11
PMC research has not been without
controversy, either. For example, the
theory that women usually are more
sensitive to alcohol premenstrually than
at other phases of the cycle, and in comparison to their male counterparts, can
be a touchy one, ripe for accusations of
male chauvinism, Halbriech pointed out.
And, indeed, he said, certain preconceptions or biases, perhaps gender-related,
may influence such research.
A definition of the phenomena of
premenstrual
changes is still being
worked out. According to Halbreich,
symptom or symptoms are considered
as PMC if:
They reoccur cyclically, du ring the
premenstrual phase ( that is, the late
luteal phase, one to seven days prior to
menstrual bleeding); they are significantly changed in severity compared to
other times in the cycle; they subside
shortly after the onset of menstrual
bleeding.
Without eve r having heard of PMS,
many women recognize changes in the

way they feel or behave just befo re the
beginning of their periods. Some women
are depressed, or go through rapid mood
swings; others lack control, are aggressive
or compulsive; still others might have an
increase in sexual drive, in appetite or in
sleep. Halbreich has found that some
women consciously alter their behavior
during this time - they drink less, for
example, or try not to take complicated,
high-performance tests.
It's difficult to say , he added, just how
many women have premenstrual changes.
Although the symptoms are quite consistent in one woman, they can vary
widely between women. Some women
have symptoms for only one day; others
for 14 days , the entire luteal phase.
"If one defines PMC as including any
noticeable changes, some people say up
to 80 per cent of women are affected,"
Halbreich said. "If you count only
women who seek treatment and in whom
the premenstrual disorder is confirmed ,
it wou ld be somewhere between two to
eight per cent of the normal women's
population . 11
The premenstrual changes are conside red a disorder if there is an impaired
function , socially or occupat ionally,
Halbreich explained.
"It also depends on how you do your
research - on what group you study,
for example," he continued. "We surveyed nursing students and over 90 pe r
cent ( reported PMC). Among women
executives or highly successful professionals, not even one ( of 23) reported
premenstrual changes .''

H

albreich has been studying PMC
for more than 10 years. Before
coming to UB in 1985, he was on the
faculty of Albert Einstein College of
Medicine in New York City. He was
previously a faculty member at the medical schools of Columbia Univers ity and

Buffalo Physician and Biomedi cal Scie ntist

�lllUSTRATlON
: GLYNISS'M:ENV

�10

Hebrew University in Israel.
Biological aspects of PMC were the
focus ofHalbreich's initial studies of the
condition. He soon realized, however,
that certain methodological issues needed
to be addressed first. For example, the
groups of women under study were not
homogeneous; they did not necessarily
reflect the diversity of types of premenstrual changes. A reliable procedure for
the clinical and research assessments of
premenstrual phenomena did not exist.
The Premenstrual Assessment Form,
subsequently developed by Halbreich
and his assoc iates , uses 95 different
items to measure changes in mood,
behavior, and physical condition during
the premenstrual period. Rather than
following the common practice of viewing PMC as a single entity, the form
reflects the wide variability of PMC.
"While there are more than 200
symptoms associated with PMS, the
major ones are depression, anxiety, and
diversified discomforts states, 11 Halbrei ch
said.

responsive to external stimuli. If taken
to a party, they can be cheered up.
Symptoms of atypical depression are
quite similar to those of premenstrual
depression. A women with premenstrual
depression can also be cheered up at a
party, for example. But there are differences, Halbreich pointed out.
Premenstrual changes can last just one
or two days. A woman would have to be
depressed for at least two weeks, however, before she could be diagnosed as
having a major depressive disorder. In
addition, unlike atypical depression,
premenstrual depression by definition is
exclusive to one phase of the menstrual
cycle, and the depression is usually not
as severe.
That leaves premenstrual depression
out of the category of major depressive
disorders. Interestingly, research has
suggested that those women who have
dysphoric PMC are more likely to
develop more depressive disorders in
the future than those who do not have
dysphoric PMC, Halbreich said.

A

I

s one of the most common of
premenstrual changes, depression
has undergone especial scrutiny. It has
been suggested, by Halbreich and others, that there may be an association
between dysphoric PMC ( characterized
by abnormal moods, especially depression) and more severe depressive disorders, and that PMC can be studied as a
model for such disorders.
Among the several types of depressive
disorders are atypical depression and
endogenous depression, or melancholia,
Halbreich said. Melancholia is associated
with a variety of biological symptoms
including decreased sleep, weight loss,
severe depression, guilt feelings, and
suicidal ideations. People with melancholia are miserable; if taken to a party,
Halbr eich offered as example, they will
not be cheered up.
Atypical depression, although possible in both men and women, is more
prevalent among women, he noted.
There's an increase in appetite and sleep
and a decrease in energy. People with
this form of depressive order are very

Late Winter '88

n recent months, his work has taken a
multidisciplinary and practical approach in the form of a research and
service clinic which evaluates and treats
women suffering from negative PMC.
The Life-Cycle Center at Millard Fillmore Hospitals, directed by Halbreich,
is staffed by two physicians, two gynecologic nurse practitioners, a psychiatric
nurse clinician, and a clinical social
worker.
"We very thoroughly evaluate each
patient - though you can't really call
them patients because we are dealing
with normal women who have symptoms only a short time during their menstrual cycles, 11 Halbreich explained. "We
are giving treatment which is aimed
mostly at the elimination of the fluctuations of the gonadal hormones."
It takes about six weeks to fully evaluate each patient at the Life-Cycle Center.
Treatment primarily takes the form of
medication - patients are given tablets
that influence the production of estrogen and progesterone, usually eliminating ovulation. Hormonal patterns are

examined through blood studies. Group
therapy and nutritional consultation will
be offered in the future.
"We schedule patients for two visits,
at specific times of the menstrual cycle
- once during the phase when they are
not expecting the symptoms and once
during the luteal phase when they're
supposedly having the symptoms,"
Halbr eich said . "Between the first visit
and the second, the patient monitors her
symptoms daily so that we can see if
these symptoms are exclusive to the
premenstrual phase and if there is a
change in fluctuations.
"We know that for about 70 per cent
of the women, the treatment is effective," he added. "We don't yet know
why it is not effective for the other 30
per cent, however, or why one drug is
effective and another isn't."
Studies will be conducted at the center to evaluate the efficacy of new treatments and test medications currently
used for other conditions but which may
relieve PMC symptoms. Last November,
a few weeks after the center opened,
patients were coming in at a rate of about
one per day, Halbreich said. The center's
capacity is two new patients per day.
If the PMC studies Halbreich and his
associates carried out at Albert Einstein
College and Columb ia University are
any indication, the Life-Cycle Center
should have no trouble finding patients.
"Many times family physicians or
gynecologists just don't have time ( for
PMC patients), but there is quite a lot of
demand," Halbreich said. "In New York
City, we ( evaluated and treated) close to
800 women over the years. We had
more potential participants than we
could handle."
Women should seek treatment for
negative PMC , according to Halbreich,
when "the severity is such that there is
an impairment of social or individual
functioning to a degree that is clearly
significant to the women and/or those
around her."
The Life-Cycle Center is located
at Millard Fillmore Hospital, 3 Gates
Circle, Buffalo. Appointments can be
made by calling 887-4444.
•

Buffa lo Physician and Biomedical Scientist

�LEECHES

11

Theirusewas an important aid in a successful
microsurgical reattachmentof a severedear

Dr. Bhangoo examines successfullyreattachedear.

BY LISA JOSEPHSON

W

hat do leeches and microsurgery have in common?
Plenty, if you ask Dr. Kulwant Bhangoo, Mercy Hospital's ch ief
of plastic surgery and clinical assistant
professor of plastic surgery at UB.
Dr. Bhangoo is the first surgeon in the
Buffalo and Western New York area to
use leeches as an adjunct in a successful
microsurgical reattachme nt of a severed
ear.
During the early hours of June 2,
1987, a SO-year-old white male patient,
Frank lin Dye, was rushed into the emergency room of Mercy Hospita l with

Buffalo Physician and Biomedical Scientist

severe facial lacerations, including amputation of his right ear. During emergency
surgery, Dr. Bhangoo used microsurgical techniques to reattach the ear. Unde r
the magnification of the operating microscope, he found a transected artery in
the ear and its corresponding stump on
the scalp of the patient . The diameter of
the small artery was less than 5 millimeters. Using the extremely delicate
technique of microsurgery, the two cut
ends of the artery were anastomosed
using sutures that are barely visible to
the naked eye. With the repair of the
arte ry , it was possible to get blood flow-

ing into the ear. However, Dr. Bhangoo
notes, in order to have a successful
microvascular
reimplantation
of an
amputated part, it is als0 necessary to
anastomose veins in addition to the
arteries; this allows the blood brought
into the part by the reconstructed arteries to d rain back out into the body's
circulatory mainstream.
Conventionally it has been extremely
difficult to find and anastomose veins in
reimplantation of the ear because the
veins in that structure are extremely
small; in th is particular case, they were
cru shed and irreparable.

Late Winter '88

�12

l
i,,
0

i .____ ___
0

Dr. Bhangoo(le/!) with patient Franklin Dye.

Soon after the surgery, the ear had
blood flowing into it, bearing testimony
to the successful arterial anastomosis.
Howeve r , a few hours later, the ear
started to turn blue and became engorged
with blood, indicating that there was
inadequate outflow of venous blood
from the ear. Dr. Bhangoo knew that
there was no other surgica l technique
that could salvage the ear from succumbing to venous strangulation.
He left the hospital k nowing that the
only way to save the ear would be to
somehow gently rid the reattached part
Lace Winter '88

of the stagnant veno u s blood until natural healing of the veins could take place.
That takes about five to seven days in a
circumstance such as this case.
In the past, in simila r situations, surgeons had made small incisions in the
reattached parts in hopes of causing sustai ned oozing that would allow for
decompression. Howeve r , Dr . Bhangoo
said, such small incisions soon clot, even
when an ticoagulants are applied topically or given int r avenous ly. Large cuts
wou ld mak e the re att ached pa rt suscep tible to in fection .

As Dr. Bhangoo walked from th e
hospital to his nearby office, it suddenly
occur red to him that here was an ideal
sit u ation to use medicinal leeches to salvage the failing reattached ear. Medicinal
leeches had been u sed very effectively in
the past for draini ng blood from patie nts.
The leeches attach th emselves wit h
microscopic bites infl icted by a row of
teeth in their circular jaws which mak es
a triradiate incisio n into the sk in. This
wound in the sk in remains ope n because
of its clever des ign.
T he leech, Dr . Bhangoo notes, secretes

Buffalo Physician and Biomedical Scientist

�in its saliva, three pharmacologically
potent substances. A local anesthetic
similar to novocaine makes the bite
painless, a fact not relevant in amputated
parts that are insensitive co pain because
of severed nerves. The second su bscance
is a potent vasodilator which opens up
the blood vessels and enhances the local
blood flow. The third and most important substance is a locally acting long
lasting anticoagulant which prevents the
blood at the bite marks from clotting
and allows for small amounts to ooze
continually from these sites for between
24-48 hours. This prolonged oozing
facilitates removal of stagnant blood in
situations such as in Mr. Dye's reattached ear.
After making several phone calls, Dr.
Bhangoo found that medici nal leeches
could be obtained from a company in
Westbury, New York, called Leeches,
USA, which is a subsidiary of Accurate
Su rgical and Scientific Instruments, a
co rporation dealing with instruments
and supplies for microsurgical procedures.
Dr . Bhangoo presented the option of
using leeches to Mr. Dye . Faced with the
possibility of losing the reattached ear,
the patient readily agreed. In fact, Dr .
Bhangoo recalled, Mr. Dye was surp risingly nonchalant and very receptive to
the idea. "It won't be the first time," he
said about the leeches. "I pulled one off
my leg as a child after play ing in a pond
many years ago."
Over the ensuing five days, three
leeches were applied to the ear daily. The
response was quite dramatic- "nothing
short of amazing," D r . Bhangoo no tes.
"The dark, plum colored ear would
become less swollen and pink in short
order with each application."
The leech attaches itself co feed and
stays on for a period of from 15-45 minutes . Mr. Dye remarked that diffe rent
leeches fed at differe nt speeds. "Some
engorged themselves with blood and
d ropped off within 15 minutes, while
othe rs fed more leisurely and took u p to
one hour ." Dr . Bhangoo is not sure what
causes the animals to stop feeding. It is

Buffalo Physician and Biomedical Scientist

conceivable, he said, that the increases in
the animal's weight may be a facto r, or
possibly there may be a built-in mechanism telling it when to quit. With one
feeding, the animals are able to susta in
themselves for from six co 12 monchs. In
order to prevent infection and cross
contamination, these leeches, which cost
about $6 apiece, are used only once and
then discarded.

npe.ople
think these
thingsmust bite you
likea king crab,but
theyjust go on like
a suctioncupand
then it is all over.
Youdon't even know
they are there.
The hardestpart is
lyingstill so as not
to disturbthem.''
Mr . Dye remarked that "people t hink
these things must bite you like a king
crab, but they just go on like a suction
cup and then it is all over. You don't
even know they are there. The ha rdest
part is lying still so as not to disturb
them."
Mr. Dye's ear has healed completely
and is one of only a very few successful
ear reimplants in the world literature,
D r. Bhangoo notes. T here are fewer than
six documented cases of successful microvascular ear reimplants, he says.

T

he leeches used are not the ordinary
pond variety animals. The supplying fir m obtains them from a leech farm
in Wales, United Kingdom. This species
ofleeches is called "Hirudo-medicinals;"
they are farmed at Biopharm in Swansea,
Wales, and then shipped to the U n ited

States via air freight . They are maintained in sterile, cool, damp containers
for shipment.
The organization in Wales, Dr. Bhangoo says, is at the center of the resurgence of medicinal leeches. Currently,
apart from their use in salvaging failing
reimplants in situations similar to that of
Mr. Dye's or as adjuncts in microvascular reattachment of ears, noses, lips,
avulsed scalps, digits, and limbs, they are
finding wider use in o t her surgical
procedures. These include correction of
venous engorgement in transposed microvascular free flaps, or pedicle flaps.
Leeches over the years have also been
used quite effective ly in decreasing swelling following trauma, such as in treating
black eyes and hematomas.
The idea of us ing leeches medicinally
stemmed from the anc ient belief that
disease was caused by an excess of corrupt blood. The principle used today is
similarly aimed at removing stagnant
and unwanted blood from parts of the
body .
The earliest written reference to the
medieval use of leeches was by a Greek
in the second century B.C. However,
medicinal leeching originated much earlier in India . The French also used
leeches. They applied up to SOat a time
to "blood patients" and found accidentally that leeches helped pulmonary
edema, cardiac failure, and hypertension. Ho wever, pat ients who did not
have these ailments were often made
wo rse. This was particularly so in conditions such as obesity. Use of the leeches
often caused anem ia and blood loss and
sometimes lead to death. By the early
twentieth century the practice of using
them for bleeding had almost died out.
Dr. Bhangoo anticipates a widespread
readoption of the technique as an adjunct
in microvascular reimplantation and also
in plastic and reconst ru ctive surgery.
But he cautioned that it has to be used
judiciously and discrimi nately. When
asked whether he will use the technique
again, he said, "If the situations are righ t
and if the patient is willing, then we will
do it again."
•

Late Wimer '88

13

�14

CE

♦

BY BRUCE S. KERSHNER

T

housands of lives lost following auto accidents and ocher
causes of severe trauma could be saved if a new surgical
approach is adopted . This is the finding of a just completed research study by UB orthopaedic surgeon Lawrence Bone,

M .D.
His study demonstrates that aggressive immediate surgery for
multiple long bone fractures significantly reduces irreversible respiratory failure and markedly reduces morbidity rates. In addition, he has found that hospital costs could be halved by the rarely
used surgical approach.
Nationwide, the primary approach is to surgically stab ilize long
bone fractures , such as occur in an auto accident, several days
later. Dr. Bone's findings provide convincing evidence that this
traditional surgical approach is a major factor in increa sed morbidiry and prolonged hospitalization for the multiply-injured patient with fractures.
"Surgeons can no longer ignore the implications of delaying
fracture stabil ization," Dr. Bone states.
The study provides the "smoking gun" against continued use of
the traditional surgical approach, Dr. Bone maintains, "because
it is the first published prospective random ized study on the
subject, and the results are statistically significant ."
While several previous retrospective studies reached the same
conclusions, retr ospect ive studies lack a control, unlike prospective studies . "Because the retrospective reviews of patients were
uncontrolled studies, their findings made little headway in con-

Late Winter '88

Dr. Lawrence Bone (left) with Dr. Steven Lasser.

vincing most of the American medical community," he commented. This skepticism has prevented the adopt ion of the new
surgical approach to trauma, and probably less than a dozen
hospitals around the nation currently use the new approach.
"Our findings were that 12 of 28 trauma patients that had
traditional delayed surgery developed respiratory failure.
However, only one of 30 such patients with prompt surgery
developed respiratory failure. That one patient (who was struck
by a train) was so injured that we expect he would have died of his
multiple, severe injuries anyway," noted the assistant professor of

Buffalo Physician and Biomedical Scientist

�15

orthopaedic surgery.
r. Bone emphasized that it is an economic breakthrough,
not just a medical breakthrough . While medical advances
often tend co increase hospital coses, chis advance would result in
reduced coses if adopted.
"le is nearly twice as expensive co delay someone's operation by
48 hours ," he explains . "Thi s is not just because of an additiona l
ten days ofhospicalizacion but also because oflonger treatment in
the Intensive Care Unit.
"Based on our study, it will cost half as much co treat multiple

D

Buffalo Physician and Biomedical Scientist

trauma patients with early fracture stabilization."
Bone's interest in the subject was sparked by che work of Dr.
John Border, who is acknowledged as one of the fathers of modern
trauma surgery. Dr. Bone was trained in trauma medicine under
Dr. Border who is a UB professor of surgery based at Erie County
Medical Center. Border helped pioneer the new creacmenc methods that enable dramat ic improvement in che survival of patients
with severe mult iple trauma.
Dr. Border developed the "Total System Approach" co trauma
pat ients. It involves six basic techniques, including aggressive

Late Winter '88

�16

immediate bone surgery {the one Or. Bone focused on),
as well as aggressive cardiopulmonary treatment, massive
protein nutritional support, and continuous ventilation of
the patient, among others. Where adopted, Border's approach has reduced the mortality rate for severe multiple
trauma from 30 per cent to 3 per cent or less. "Dr.
Border's studies have focused on a broader range of
trauma medicine concerns while mine focused only on
orthopaedic surgery," Dr. Bone
-----.--remarked.
Dr. Border's research, while it
demonstrated the importance of
aggressive bone surgery, relied on
retrospective studies only. This is
one of several reasons why this
approach is still rarely used. It is
also the reason that Dr. Bone
decided to undertake this study in
1984.
"! saw a need for a study that
would definitively establish the
role of early fixation in the trauma
patient. Because the approach was
viewed with skepticism by the
medical community, I saw chat this
kind of study could change this
skepticism," he related.
While chief orthopaedic resident at Parkland Hospital, University of Texas-Dallas (1984 to
1986), he became project director
for the study. It was funded by a
$64,000 grant from the Orthopaedic Research and Education
Foundation. Dr. Kenneth Johnson,
University of Texas associate professor of orthopaedic
surgery,
served as co-investigator.
Dr. Bone's prospective randomized study compared 125 trauma
patients who had femur fractures.
They were separated into two
groups, one which had early stabilization of bone fractures and one which had de layed stabilization. These two groups were in turn divided by level of injury,
whether moderate or severe.
In the group with moderate inju r y levels, those with delayed
su rgery showed 2.6 times greater levels of abnormal arterial
blood gases than those with immediate surgery. Pulmonary
emboli occurred in 3.3 per cent of the delayed group, but none
in the immediate group had this difficulty.
For the group with severe injuries, differences were much
more dramatic. Ventilation support and admission to the ICU
were required for mo re than twice as many in the delayed
surgery group as in the immediate surgery group; amount of
time spent in the ICU was almost three times greater in the
Late Winter '88

delayed group; major pulmonary failure was 13 times greater
( 42.9 per cent vs. 3.3 per cent) for the delayed vs. the immediate
surgery group.
The reason pulmonary failure occurs from the multiple bone
fractures has to do with the reaction of the body following
severe trauma. It appears, Or. Bone states, "that fat from the
fracture site, from the liver and from adipose tissue form emboli
and other vascular cellular elements that lodge in the lung,
---,
mechanically occluding or constricting smaller capillaries." This results
in an irreversible reduction in oxygen for the lung.
Dr. Bone has presented his findings at the American Academy of
Orthopaedic Surgeons meeting in
San Francisco, at the American
Orthopaedics
Association
in
Washington,
D.C., and at the
World Surgical Conference in Australia this fall.
"I have received a very, very positive reaction from fellow surgeons
so far," he says. He expects to pub-lish his results in a primary orthopaedic journal.
Or. Bone returned to Buffalo in
1986 after he was invited to join
UB's faculty. But his connections to
the area are not just career-related.
He is a Buffalo native, his family
lives in Western New York, and
both he and his father are UB medical alumni.
Besides receiving his M.O. and
completing his surgical residency at
UB, Or. Bone has participated in
fellowships in Switzerland, Germany, and Texas. He is both director of the Musculoskeletal Trauma
Service at Erie County Medical
Center and acting chief of the Division of Orthopaedics at Buffalo
Veterans Hospital. He has other
staff positions at Buffalo General and Children's hospitals .
Dr. Bone is unusual because he is one of only several physicians nationw ide who is board certified in both orthopaedic
surgery and general surgery.
This year, Dr. Bone was honored with the American Orthopaedic Association Traveling Fellowship. He is the author of 15
publications.
He hopes his findings will spark interest in the new approach
to trauma so that the advances will become standard techniques.
Regarding his uniquely fitting last name, the bone surgeon
remarks, "I get a little bit of ribbing from my fellow physicians
once in a while. On the other hand, none of my patients ever
forgets my name."
•

Buffalo Physician and Biomedical Scientist

�17

ROSWELL
REPORT
WASKEY
TOGENETIC BREAKTHROUGH
BY COLLEEN M. KARUZA

A

unique case report of a Roswell
Park patient was the key to a breakthrough genetic study published
recently by British scientists.
Sir Walter Bod mer, of the Imperial Cancer
Research Fund, in London, and his colleagues have provided compelling evidence
demonstrating that the genetic defect responsible for familial adenomatous polyposis - a
premalignant condition leading primarily to
colorectal cancer - resides in the long arm of
chromosome 5. Their study was published in
the August 13 issue of Nature, a well-known
British journal.
In an article published on the same date in
the New York Times, Sir Walter acknowledged that his group's research was triggered
by a 1986 published case report from Roswell Park involving a mentally retarded
patient with colorectal cancer, extensive
adenomatous polyposis and several unusual
chromosomal anomalies. This brief report,
which appeared in the American Journal of
Medical Genetics,was written by Lemuel Herrera, M.D., FACS, director of the Familial
Adenomatous Polyposis Registry of Western New York, and several members of Roswell Park's Genetics &amp; Endocrinology
Department. Or. Herrera is an assistant professor of surgery at UB.
Familial adenomatous polyposis is an
autosomal dominant, premalignant condition. If one parent carries the gene for this
condition, 50 per cent of the offspring will
inherit the gene. "If an offspring develops
colon polyps," said Or. Herrera, "there is a
99 per cent chance that he or she will develop
cancer by age 35." Moreover, only those
affected may transmit the genetic defect to
their children. Because familial polyposis is
premalignant primarily for colorectal cancer,
it is, according to Dr. Herrea, "the classic
prototype for studying the genetic back-

Buffalo Physician and Biomedical Scientist

ground of the number two cancer killer in
both the U.S. and Great Britain." Of the
140,000 new cases diagnosed in the United
States in l 987, it is estimated that 25 per cent
to 40 per cent may be linked to a genetic
defect.
The human genome has been calculated to
have l 00,000 genes distributed in 23 pairs of
chromosomes. Chromosomes can be compared to sentences that contain an individual's genetic blueprint, while the genes are the
words. The chemical bases that make up
these genes are the letters that spell out an
individual's inheritance.
In the report, Dr. Herrera, who is also a
clinician in Roswell Park's Surgical Oncology Department, evaluated a mentally retarded male patient who had undergone a
proctocolectomy for a colon carpeted with
adenomatous polyps. The resected specimen
contained two well-differentiated colorectal
cancers. Four years later, the patient developed a large mass which occupied the entire
abdominal cavity and was ultimately responsible for his death.
An autopsy revealed an enormous desmoid tumor and other congenital anomalies,
including a horseshoe kidney, a liver consisting only of the right lobe, absence of the
gallbladder, rounded configuration of the
heart, and deformed feet.
Subsequent cytogenetic studies showed
that the patient's mother had normal chromosomes, while the father had an enlarged
satellite area on chromosome 22. A similar
assessment of the patient revealed that a portion of chromosome 5 was missing; and that
the same enlarged satellite area appeared on
chromosome 22. Although the family had no
known history of colorcctal cancer or adenomatous polyposis, Dr. Herrea and his colleagues believed that the combination of
colonic adenomatous polyps, cancer and the

desmoid tumor represented a mutant of
familial polyposis often labelled as Gardner's
syndrome.

G

ardner's syndrome is characterized by
several abnormal growths caused by a
single dominant gene, with the colon being
the central tumor site. Familial polyposis has
been claimed to involve just colon cancer,
and not the other anomalies associated with
Gardner's syndrome. Recently, there has
been evidence to suggest that Gardner's syndrome is the full-blown phenotypic manifestation of the familial polyposis gene.
Only five cases of abnormalities
on
chromosome 5 had been reported previously
in the literature, with Roswell Park being the
first and only research institute to describe a
constitutional chromosome anomaly in a
patient with Gardner's syndrome and colorectal cancer. Despite several decades of
intensive research, this was the first time that
a cytogenetic finding led to the discovery of a
recessive genetic effect in one of the most
common types of cancer. "At that point,
however," said Or. Herrera, "more cases
needed to be studied to establish the possible
significance of this cyrogeneric abnormality
in familial polyposis."
Prompted by the Roswell Park report, the
British research team studied several families
with adenomatous polyposis syndrome from
the St. Mark's Hospital Registry in London.
For those individuals who later developed
colorectal cancer, variants in the generic
material were disclosed by ONA recombinant techniques. This indicated a gene deletion on chromosome 5. The British team not
only corroborated rhe results of Dr. Herrera's research that indicated that the defect
was in bands 2 l and 22 of the long arm of
chromosome S, but they also established an

Lare

Winter '88

�18
assoc1at1on for the gene deletion in both
inherited and sporadic forms of colon cance r.
With these findings, Sir Walter contends
chat teams currently working on this project
should be able co sequence the chemical
bases of the gene within the next few years. If
the promise of the new studies is borne out,
periodic blood tests will be available to
detect the defective gene in individuals at
greatest risk for colorectal cance r; and knowing the gene sequence may lead to more effective treatments. As Dr. Herrera explains,
"This research will provide the basis for presymptomatic or prenatal diagnosis of familial
polyposis as well as the early detection of a
significant percentage of colorectal cancers
chat are often associated with the presence of
adenomatous polyps in the general population.11

Dr. Herrera's collaborators on the report
were Surabhi Kakati, Ph.D.; L. Gibas, Gen
Pietrzak, and Avery A, Sandberg, M.D.
•

Epidemiologist finds
link between SIDS &amp;
retarded fetal growth

N

ew evidence linking Sudden Infant Death Syndrome (SIDS)
with retarded growth of the fetus
during pregnancy has been reported by a
UB epidemiologist.
According to the study conducted by
Germaine Buck, Ph.D., babies who die of
SIDS typically, at birth, weigh less than
five pounds and five ounces, measure less
than 20 inches long, and are delivered
earlier than 3 7 weeks gestation.
Buck's findings were presented lastJune
at the meeting of the Society for Epidemiologic Research in Amherst, Mass.
The study, conducted by Buck as a doctorial candidate in UB's Department of Social and Preventive Medicine, also won
the Society's prestigious Abraham Lilienfeld Award for best student research. She
is currently a clinical assistant professor in
the department.
SIDS, which swiftly and without warning kills, usually within the first six
months after birth, has no known cause.
Late Winter '88

SIDS babies are typically normal, healthy
infants who are found dead, usually in
their cribs. This killer of infants gives no
signs, no symptoms, and it strikes rich and
poor alike.
"Diagnosis of SIDS at autopsy is
always a diagnosis of exclusion; it
remains as the likeliest cause of death
when all other diseases and disorders
have been excluded," says Buck.
The UB researcher says reduction in
birth weight and birth length, called proportional growth retardation, which the
SIDS infants share, may be related to insults which occur to the fetus early in the
pregnancy.
These insults include the mother's consumption of alcohol; consumption of drugs
- illegal, prescription, or over-the-counter; inadequate nutrition, and exposure to
chemicals or other substances in the environment which can affect fetal growth.
These may be particularly criticaI in the
earliest weeks and months of pregnancy,
Buck believes.
"We know, for instance, the fetus
achieves about 75 per cent of its birth
length by the end of the second trimester
of pregnancy," she points out. Therefore,
it may be during this time that insults which
would slow the growth involving length
could occur.

I

n general, risk of SIDS decreases with
increase in infant size.
SIDS, which was formally recognized
during the early 1960s, occurs in two to
three live births pe r thousand in the population of developed nations around the
world, a rate which remains unc hanged
after two decades.
It is extremely difficult, says Buck, to
estimate the figures for SIDS in developing
nations because infant s there are likely to
die within the first year oflife from a variety of diseases and problems connected
with nutrition and environment.
Buck's study examined birth weight,
birth length, head circumference and
length of time in uterofor all babies born in
New York State in 1974, excluding New

Dr. Gennaine Buck
York City. She then examined identical
factors for infant deaths in New York State
for 1974 and 1975. A total of 148autopsyconfirmed cases of SIDS, 114 infant deaths
from all other causes including trauma,
and 355 living infants who had reached
their first birthday were compared in the
study.
"Even when I examined factors such as
education levels and occupations of the
parents of the babies in the three groups,
none of these data suggested that socioeconomic , educational or health status of
the parents affected the SIDS risk," Buck
points out.
The only factors, she says, which the
SIDS babies had in common were birth
weight of less than five pounds, five
ounces, birth length ofless than 20 inch es
and a gestation period of less than 37
weeks.
"This is not to say that all babies which
fit this pattern will die of SIDS," she emphasizes, "it only suggests that these factors which are the result of delayed
development which occurs in pregnancy
put them at higher risk than average."

Buffalo Physician and Biomedical Scientist

\
J

�19

Roswell skin cancer study
enters second year of tests

R

oswell Park is entering its second year
in a nationwide research study designed to test the vitamin A derivative, isotretinoin, as a prophy lactic against
basal cell carcinoma. This five-year study was
made possible through a $500,000 research
grant from the National Cancer Institute
(NCI) .
~

Basal cell carcinoma, a disorderly growth of
cells near the skin's surface, is the most common - and most commonly cured - human
~ malignancy. Although cure is virtua lly guaran6 teed with early detection and treatment, persons who have had basal cell carcinomas in the
... past are likely to see new skin lesions developing in the future. The first tumor may appear on
the face; the next one on the neck. Cur rently,
ased on the results of her study, Buck
there is no way to prevent new basal cell carsays it wou ld appear that the earlier
cinomas from forming.
the mothe r-to-be r eceives prenatal counThe NCI has been investigating drugs that
seling and examination, the better for the
would arrest or disrupt this regeneration. In a
infant.
pilot study conducted by the NCI, a synthetic
derivative of vitamin A called isotrecinoin
"Many women may believe that it's not
effectively slowed the development of new skin
important to check in with the doctor o r
cancers in a small group of patients treated for
clinic until they 'show' weight gain. Othbasal cell carcinomas.
ers may not believe they are pregnant in
Basedon this preliminary evidence, the NCI
the first two months, especially if they
launched an intensive five-year clinical study of
have a history of irregula r menstrual pe r ilow-dose isocrecinoin as a prophylactic against
ods," Buc k points out . And some physibasal cell carcinoma . Eight study sires around
cians have suggested women not schedule
the U.S., including Roswell Park, were sethei r first prenatal visit u ntil after they 've
lected to conduct the cooperative clinical trimissed two periods.
als. Currently, more than 800 patients nationwide are enrolled in the study.
''The study suggests, howeve r , t h at the
At the Roswell Park study site, Dr. Howard
earlier the mother-to-be gets adequate nuL. Stoll, director of the Dermatology Section
trition, abstains from alcohol and tobacco
and clinical associate professor of dermatology,
and other chemicals including illegal
is the principal investigator; and Ors. B. Dale
drugs as well as medications, the less lik ely
Wilson and Corne lie Jones, clinical assistant
she may be to r un the risk of the baby dying
professor of dermatology, are co-investigators;
later from SIDS," Buck surmises .
Barbara Slusarski, R. N., M.S., is the study
Buck's study was conducted with grant
coordinator.
monies from the National SIDS FoundaThe Roswell Park study began in the spring
tion and assistance from the New York
of 1986,with 68 skin cancer patients volunteerSt ate Health Depa r tment .
•
ing as subjects. "The patient s have been ran-Mary Beth Spina
domly assigned to one of two groups," said Mrs.

i
i

---------

~-----------

B

\
j

Buffalo Physician and Biomedical Scientist

i

Slusarski. "One receives a placebo; the other
group, the isotretinoin." The study is "doubleblinded," which means that neither the patient
nor the physician knows which agent is being
administered.
Each patient is required to take two fivemilligram capsules each day and make regular
visits co the Roswell Park Dermatology Clin ic.
After three years, study researchers will compare che groups to see if the isocretinoin group
had fewer basal cell carcinomas . Although they
will stop taking the capsules after the third
year, patients will still return to the clinic for
routine follow-up visits every six months for
II patients have been intwo more years. ''.A.
formed that should we find proof chat the isotretinoin is effective, the 'blind code' will be
broken, and the drug will be prescribed for all
study participants," explained Mrs. Slusarski.
Conversely, if the drug proves harmful at an y
time, the study will be abruptly discontinued.
And how safe is isotretinoin? "Physicians
have successfully treated more than 1,000 acne
pat ients with isotretinoin at doses three to ten
times higher than the 10 milligram daily dose
in our study," said Mrs. Slusarski. ''.l\swith any
medication, side-effects can occur; however,
we feel that, because of the low dosage, any
side-effects that do occur are very unlikely to be
dangerous."
Some of the possible side-effects are chapped
lips, mild nosebleeds, and tired or irritated
eyes. This may occur because isotrecinoin has a
drying effect. Unlike vitamin A, isocrecinoin
appears to have no deleterious effects on the
liver or kidney. "However, if eithe r organ malfunctions, the body may be unable to break
down che compound," said Mrs. Slusarski. "We
routinely test patients' blood to ensure that
these viral organs work normally."
Ac che end of the trial, patients will be notified of any significant results, but chat isn't the
only benefit they'll derive for their participation . During the five years of the study, patients receive free dermatological care,
including check-ups and treatment.
•

Late Winter '88

�20

Dental researchersJoseph Margarone (left) and Charles Liebow demonstratehow
laserwill be used for surgery.

LASERUSEDTOTREATSOFT
TISSUELESIONS
IN MOUTH
BY MARY BETH SPINA

P

ioneering research in the UB School
of Dental Medicine shows that soft
tissue lesions in the mouth can be
successfully biopsied or removed on an outpatient basis with a pulsing carbon dioxide
laser beam.
Although the laser "light knife" has been
used to treat a var iety of medical problems,
its use in the oral cavity has been largely
limited to experimental surgery under general anesthetic.
Charles Liebow, D.M.D., Ph.D., told the
Society of Optical and Quantum Electronics
in Lake Tahoe, Nevada, in December that a
UB team has successfully used the laser to
treat some 15 patients. Four had fibrotic
outgrowths or "callouses"; four ochers had
hemangiomas; two were diagnosed with the
potentially precancerous lesion leukoplakia;
and five had papillary hyperplasia.
The pulsing rather than continuous laser
beam has dis t inct advantages in the oral cavity, said Lie bow, an associate professor of oral

Late Winter '88

surgery here. The continuous beam can produce inflammation in healthy tissue adjacent
to the lesion being removed .
"Patients who underwent treatment with
the pulsing laser experienced no post operative bleeding and little, if any, discomfort
compared to what would be expected using
traditional surgical procedures," he emphasized.
Since the laser energy source, which literally boils and vaporizes tissue, can deliver a
pulsing beam in l / 100,000th of a second in
an area as small as one-tenth of a millimeter,
small amounts of tissue can be lased.
"Microscopic capabilities combined with
the laser gives the oral surgeon a great deal of
control in a precise manner that may not
always be possible with traditional surgery
methods," Liebow adds. Deep lesions can be
lased in layers; intact biopsy samples can be
removed by using the laser to cut around and
under tissue in a pie-shaped wedge.
"While the carbon dioxide laser has proved

itself successful as a surgeon's tool in the oral
cavity, I don't anticipate every oral surgeon
will use it," he predicted. He believes cases
which can benefit most from the laser will be
referred to tertiary dental centers where clinicians specially tr ained in its use will perform the procedure.
Laser treatment does not appear applicable for oral surgery involving bone no r may it
be recommended fo r certain other procedures in the mouth, Liebow said. The UB
team has, however, used the carbon dioxide
laser to treat one case of periodontal disease
with good results.
Liebow said that the researchers in the
Department of Oral Surgery are involved in
other ongoing research which may expand
applications of laser technology.
Others involved in the study include
Robert E. Braun, D.D.S., Joseph Natiella,
D.D.S.,Joseph Margarone, D.D.S. and Laurie
Hartman, D.D.S ., all faculty in the UB
School of Dental Medicine.
•

Buffalo Physician and Biomedical Scientist

�21

e Buffalo General Hospital, a major
eaching hospital of the State University of New York at Buffalo, is
establishing the State's second heart transplant center.
Among institutions which also submitted
proposals for the heart transplant center
were Mt. Sinai Hospital and Montefiore
Medical Center in New York City and Strong
Memorial Hospital in Rochester. The State's
only established center is at ColumbiaPresbyterian Medical Center in New York.
The new heart transplant center at Buffalo
General will be directed by Robert M.
Mentzer Jr., M .D ., head of the Division of
Cardiothoracic Surgery at the UB School of
Medicine and Biomedical Sciences and chief
of Buffalo General's Department of Surgery.
The center will be heavily oriented toward
research aspects of cardiovascular surgery,
including follow-up studies of transplant
patients and the development of bioengineering devices such as artificial hearts and support systems for surgery, Mentzer said.
"The Cardiac Transplant Center is an
important step forward in the development
of Buffalo as a national center of excellence
for health care," UB President Steven B.
Sample commented. "The establishmen t of
the center is the result of cooperation among
the University's eight teaching hospitals, including Roswell Park Memorial Institute , the
strong support of the community, and our
faculty's experience in heart transplantation
at the Buffalo Veterans Administration Medical Center, where 12 heart transplants have
already been performed."
"The Cardiac Transplant Center will
enhance the Medical School's academic program in cardiovascular surgery," said John
Naughton, M.D., vice president for clinical
affairs and dean of UB's School of Medicine
and Biomedical Sciences. He also emphasized
the cooperative effort among the University's eight teach ing hospitals and the involvement of the Western New York Health
Sciences Consortium in developing and supporting Buffalo's program in heart transplantation.
Fourteen heart transplants are projected
during the first year of operation with an
average of 25 each year after that, Mentzer
said. The Organ Procurement Agency of

Buffalo Physician and Biomedical Scientist

STATE'S
2ND HEART
TRANSPLANT
CENTER
ESTABLISHED
HERE
BY LINDA GRACE-KOBA$

THEBUFFALO
ENl:RAL
HOSPITAL

.,"
-~n. ...
BUFFALO
GENERAL
HOSPITAL

I
z
i5
~

i
Q
:.,__ _

________________

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~

President Sam/1le at podium d111·ingheart trans/1lan1 /Jrcss conference.

Western New York will handle organ location and procurement.
Mentzer noted that no additional hospital
construction or equipment is required before
the program's start-up and that two operating rooms, intensive care units, and a newly
created stepdown unit on the 13th floor in a
new medical tower building will easily accommodate the cardiac transplant procedures.
Mentzer, with Joginder Bhayana, M.D.,
will co-direct a cardiac transplant team con-

sisting of University at Buffalo facu lty surgeons from Buffalo Children's Hospira!,
Buffalo Veterans Administration Medical
Center and Buffalo General. In addition to
Mentzer and Bhayana, team members include
Jacob Bergsland, M.D., Thomas Lajos, M.D.,
A. Norman Lewin, M.D., Gary Lofland,
M.D., Syed T. Raza, M.D., and Theodore
Spooner, M.D. Since 1984, this team has
performed a total of 14 cardiac transplants in
Buffalo.

Late Winter '88

�22

Also involved in the heart transplant program are Francis J. Klocke, M.D., SUNYBuffalo professor of psysiology and medicine, who this year serves as president of the
American College of Cardiology, and Lewis
M. Flint, M .D., chairman of the U niversity' s
Department of Surgery.
All persons involved in the Buffalo Cardiac Transplant Center emphasize the cooperative effort that resulted in its approval by
the State. Other principals in the program's
development include William V. Kinnard
Jr., M.D., president and chief executive
officer of Buffalo General Hospital; John E.
Friedlander, Buffalo General's executive vice
president, and Andrew J. Rudnick, president
of the Greater Buffalo Development Foundation, Inc.
Mentzer said the comprehensive nature of
Buffalo's program in cardiovascular surgery
could not be achieved by a single institution.
Officials at Buffalo's renowned cancer
research institute, Roswell Park Memorial
Institute, have supported efforts to establish
transplantation programs for heart and bone
marrow transplants, he said. Pediatric cardiovascular surgery and research studies have
been under way at Buffalo Children's Hospital, while researchers at the Buffalo VA medical center have developed a highly regarded
program in heart transplants and cardiovascular surgery .
He also cited Klocke's reputation as a
leader in the study of coronary blood flow in
humans who has performed important studies in that discipline. Klocke will initiate
new coronary blood flow studies in transplant patients, Mentzer said, particularly in
the area of atherosclerosis. Other research
studies to be performed within the new center will be a systematic investigation of coronary blood flow in transplant patients. Leon
Farhi, M.D., chairman of the University's
Department of Physiology, is a leader in respiratory physiology who will participate
actively in clinical studies investigating
changes in blood circulation after a patient
undergoes a heart transplant.
"Most heart transplant cente rs are not
prepared to study changes in the body after
transplants in as comprehensive a manner as
we are able to because we have the involvement of so many University departments and
teaching hospitals," Mentzer said. "In extensive follow-up studies, we will be looking at

Late Winter '88

Governor Cuomo visits heart 1:rnnsplan1 cenwr following announ cement of its cstablishmcnL

ways to help patients after their heart transplants through Buffalo General's Cardiovascular Life Sciences Program."
Another unique aspect of the Buffalo Cardiac Transplant Center is the University's
commitment
to biotechnology,
Mentzer
noted.
"We are also going to investigate support
systems to maintain patients and the furthe r
development of cardiovascular technology,"
he said. "We are prepared to look at the
experimental development of artificial hearts
over the next several years. We have associations w~th bioengineering experts at the University and with its Health-care Instruments
and Devices Institute.

"Most other cardiac transplant programs
in the country do not have as well rounded a
research base to expand their programs as we
do in Buffalo. Our goal is to establish ourselves as a transplantation center as good as
any in the country."
Mentzer was recruited by the University at
Buffalo to head its Cardiac Transplant Program from the University of Virginia, where
he established a reputation as one of the leading young researchers in cardiovascular
surgery in the country, University officials
said. His awards include a National Institutes
of Health Research Career Development
Award and two Public Health Service
Awards.
•

Buffalo Physician and Biomedical Scientist

�23

Consortium wi ll focu s
on marrow tran splan ts

B

one marrow transplants are the initial
focus of the new consortium formed
by three medical institutions: UB
School of Medicine and Biomedical Sciences, Roswell Park Memorial Institute, and
the University of Rochester Medical Center
and School of Medicine and Dentistry.
The purpose of the consortium is to share
resources in transplantation medicine in the
areas of patient care, research, and medical
education.
The consortium is also exploring the possibility of sharing resources outside trans-

Buffalo Physician and Biomedical Scientist

plant medicine.
"This cooperative agreement is a good
indicator of further inter-institutional cooperation in the two communities of Buffalo
and Rochester," said John Naughton, M.D.,
UB's vice president for clinical affairs and
dean of the medical school. "Sharing of our
expertise in bone marrow transplantation is a
sign of more things to come."
"The consortium is unique in that it br ings
together in a single program the resources of a
nationally designated Comprehensive Cancer
Center and two university teaching hospitals
recognized for thei r excellence, for the benefits of patients throughout Upstate, Central
and Western New York." said Thomas B.

Tomasi, M.D., Ph.D., director of Roswell
Park Memorial Institute (RPMI).
"Each institution
will bring unique
strengths to the program."
"We're looking at an era where cooperative
use of resources will be crucial if expensive
and complex medical technology is to serve
the public efficiently," said Paul F. Griner,
M.D., director of the Medical Center at the
University of Rochester.
The cooperative agreement will establish
interactions among researchers on a formal
basis, Tomasi said.
"The three institutions will work toward
sharing common interests," Naughton said,
adding that the agreement will include cooperation and exchange in research and education.
At first, the interchange will involve faculty
visiting neighboring institutions to work on
joint research, according to Naughton. Later,
the exchange could involve the exchange of
senior residents and special fellows from the
two medical schools.
It is proposed in the consortium agreement that a joint program for bone marrow
transplantation be established at Roswell
Park Memorial Institute and Strong Memorial Hospital of the University of Rochester
Medical Center, enabling physicians to perform allogeneic (donated) bone marrow transplants for patients suffering from leukemia,
aplastic anemia and related diseases.
The bone marrow transplantation program at RPM! and Strong Memorial will
serve patients in Western New York as well
as the Finger Lakes and Central New York.
Tomasi said RPMI currently offers autologous bone marrow transplants in its clinic.
(Autologous transplants involve drawing
marrow fluid from the patient, treating the
fluid, then returning the marrow to the
patient.} This procedure is less complicated
than allogeneic transplants, which require
special facilities.
"Research is needed in the bone marrow
transplant area, including gene thereapy,"
Tomasi said, adding that gene therapy, now
an experimental procedure, entails inserting
genetic material into the cells to replace missing genes.
Tomasi's research team is also studying the
reasons why organs are rejected when transplanted to a patient. This research may result
in improved methods of transplanting organs,
such as the heart or liver.
•

Late Winter '88

�24

JOHNNAUGHTON
:
DEAN&amp; VICEPRESIDENT
BY CONNIE OSW ALO STOFKO

I

t's not easy to tell where one of John
Naughton's jobs stops and the other
starts.
Naughton is vice president for clinical
affairs. He's also dean of the School of Medicine and Biomedical Sciences.
When he's wearing his vice presidential
hat, he reports to President Steven Sample.
In his role of dean, he reports to Provost
William Greiner.
"Often I report to both together because
you can't separate the roles out," Naughton
noted.
As dean of the medical school, he takes
care of the school's academic needs. As vice
president, his job is to work with the local
hospital system. Clinical education is different in Buffalo than it is in other places
because UB uses a system of affiliated hospitals instead of a single teaching hospital as is
the case with most others.
"To make the system work in Buffalo, we
need the cooperation of the hospitals and the
school," Naughton said. "To develop the
system was the job of the vice president for
clinical affairs. To keep it going is the dean's
job."
Since about 1983, his duties as vice president have remained stable, he indicated.
"My job is to be the University's representative and officer to the teaching hospitals in
Buffalo," Naughton said.
It's his job to represent not only the medical school, but the other schools and
departments that have programs in the local
hospitals. However, Naughton isn't placed

Late Winter '88

over the other deans.
"l have oversight in relation to affiliation
needs, but not over programs," he explained.
The affiliation agreements with hospitals
are now cent ralized in rhe Office of the Vice
President for Clinical Affairs. Originally,
they were in the office of Edward W. Doty,
vice president for finance and management.
Any department that sends students to
work in a hospital must have an affiliation
agreement, Naughton said. Each school pretty
much works out the relationships with the
hospitals itself.
Units with affiliation agreements include
the School of Dental Medicine, School of
Nursing, School of Health Related Professions, Department of Communica tive Disorders and Diseases, Psychology Department,
and School of Social Work.

A

s vice president, Naughton also oversees lease agreements with the hospitals. UB pays hospitals for space it uses at
their facilities.
He is also responsible for the clinical practice plans for both the medical school and
dental school.
Another of his vice presidential duties
calls for Naughton to oversee programmatic
issues concerned with clinical practice. For
instance, he has been working on the attempt
to get a heart transplant center in Buffalo.
That is, in large part, a patient care issue, but
it requires a strong academic presence, he
pointed out.

But even this example is one of the areas
that overlaps with his role as dean, he
pointed out.
Coordinating the residency programs is
another example of the mixture of his roles,
he said.
Residents are paid by the hospital, so
they're agents of the hospital. But they're
there for an education, which falls into his
role as dean, he explained.
The residency program is operated by the
Unive rsity faculty who are chairmen of the
clinical departments. Invariably, they're also
chiefs of the same clinical areas at the
hospitals.
Naughton's position as vice president
differs from the other vice presidencies in
one big way - it's a staff position rather than
a line position, he explained. That means that
although he reports to President Sample as
the other vice presidents do, he has no control over resources when wearing his vice
presidential hat.
•

Editor's Note: The Reporter, ihe campus'
weekly newspaper, has been running a series of
articles on the University's organizational
srructure, explaining how each vice presidential
area is set up and how it functions. This article on
chevice president for clinical affairs attempts to
delineate the differences and complementary
relationships between John Naughwn's two
administrative roles as both vice president for
clinical affairs and dean of medicine and
biomedical sciences.

Buffalo Physician and Biomedical Scientist

�25

PHOTODOUG LEVERE

�26

It'searthshaking,but rwt
anotherPlague,Mohnsays

BY MARY BETH SPINA

U

B immunologist James F. Mohn,
M.D., describes the AIDS crisis as
"the most earthshaking infection of
this century," but cautions against comparing it with The Plague - The Black Death which killed about one-fourth of Europe
around the 14th century.
Speaking at a seminar organized by the
Depa rtm ent of Microbiology on AIDS and
other venereal diseases, Mohn noted that
unlike The Plague, which in its pneumonic
form spread rapidly through casual contact,
the AIDS virus is transmitted only in blood
and semen and by intimate sexual contact.
Transmission appears to be primarily by
means of unprotected intercourse with an
infected partner, contaminated needles shared
by IV drug abusers, transplancental exchange
during pregnancy from an infected woman to
her fetus, and - much less frequently t0day
- transfusion of blood products.
Very rare instances have been reported
where health workers, in no other high risk
group for AIDS, accidentally received the
virus from an infected patient through a needle prick, or through infected blood entering
an open sore or scratch.
Mohn noted that while there's no cure for
the virus - HIV 1,2,3 - great strides have
been made since the syndrome was first recognized a half-dozen years ago.
Not only has the virus been identified, but
screening tests sensitive to and specific for
HIV antibodies have been developed to minimize its spread through the human blood
supply. In addition, there are continuing
efforts to educate health workers as well as
the general public about methods they should

Late Winter '88

employ to prevent the spread of AIDS.
"All we have going for us now is prevention through essentially personal hygiene
methods," said Mohn, director ofUB's Ernest Witebsky Center for Immunology. He
also serves as chairman of the New York
State Council on Human Blood and Transfusion Services which Gov. Mario Cuomo
charged to be responsible for insuring safety
of the blood supply.
Mohn said that although there is some
promise for AZT, the drug currently approved
for treatment of AIDS patients, it has t0xic
side effects. The best hope, he believes, is for
an effective vaccine to be developed.
The lethal effects of the retrovirus HIV can
be blamed on the type of cells it recognizes
and attacks as well as on the fact that it can
remain latent or inactive but alive for an
undetermined number of years in the human
body, said Thomas Flanagan, Ph.D., a virologist and chairman of the Department of
Microbiology.
While other viruses have a particular
attraction for certain types of human cells,
HIV is especially deadly because it recognizes
and infects primarily T4 helper cells and, to a
lesser extent, certain types of cells in brain
tissue.
Because the virus attacks, infiltrates, and
renders impotent these important T helper
cells, the AIDS patient falls victim to a number
of organisms found normally in the body and
normally held in check by cellular immunity.
Among these are the parasite Pneumocystis
carinii.

S ince the humoral immune system is compromised to a lesser degree than the cellular

Buffalo Physicianand BiomedicalScientist

��28

one, it is more unusual for AIDS patients to
die from exposure to infectious agents for
which they have developed antibodies in the
past.
Flanagan noted that, compared to other
viruses, HIV appears relatively "inefficient"
in its transmission. Hepatitis B, for instance,
which may also be spread by infected blood,
is considerably more efficient in producing
active disease than · HIV. This difference,
Flanagan hypothesized, may lie in the amount
of the virus which may be transmitted per
occurrence.
Especially of concern are babies born to
HlV positive mothers.
"Fifty per cent of these infants are born
HIV positive with a certain number going on
to develop active cases of AIDS," Flanagan
said. But among those born HIV negative to
positive mothers, it cannot be determined
how many will undergo seroconversion or
how many years could elapse before this
might occur.

T

imothy Murphy, M.D., a faculty
member in the Department of Medicine, told the audience that physicians can
estimate the individual AIDS patient's
expected survival rate from time of diagnosis
to death based upon the syndrome's initial
manifestations.
"Patients who first present with Kaposi's
sarcoma will live about 125 weeks after diagnosis, compared to 35 weeks for those
initially presenting with Pneumocysciscarinii
pneumonia and 18 weeks for those first
affected by other opportunistic infections or
disease," Murphy said. In addition to opportunistic infections, some patients develop
certain types of brain tumors typically found
only in AIDS patients.
Murphy's case presentations showed the
abstract term "fatal" takes on a more tragic
picture: most patients with AIDS will die
within three years of diagnosis.
Although laboratory screening tests for
HIV antibodies can assist the physician in
confirming a suspected diagnosis of AIDS,
they are more important as a means of
screening the human blood supply, according to Roger Cunningham, Ph.D., associate

Late Winter '88

professor of microbiology.
Screening at blood banks features an initial
ELISA (Enzyme Linked Immunosassay). A
test sensitive for HIV antibodies, ELISA is
repeated twice if the first result is positive.
"False positives can result from antibodies
in the blood which are not anti-HIV, reacting
with material from the cell culture used in
growing the virus for use in the test," said
Cunningham.
If the prospective donor has two positive
ELISA results, the blood is tested using the
electrophoretic Western Blot, which while as
sensitive as ELISA, is more specific.
"If the donor is repeatedly ELISA positive
or positive on the Western Blot, he or she is
barred from blood donations but still may
not develop an active infection from HIV,"
he added.
There is no guarantee that those who are
HIV negative on these tests are not incubating the virus and might not convert to positive at a later time. But, Cunningham noted,
"all that can be done is being done" to protect the human blood supply.
"The time required from exposure to the
virus co a positive test result is something we
still don't know," he explained.
Asked later about a recent finding by
Johns Hopkins researchers that suggests that
some patients who are seropositive for HIV
later may convert to a negative test result,
Cunningham said this discovery may indicate HIV "acts just like other viruses" in
certain aspects of its behavior.
"What these researchers have found is
what we might suspect could happen," he
added.

I

n addition to scientific questions about
HlV and the AIDS syndrome, there are
legal and ethical considerations which confront the physician and society, said Cheryl
Nohejl, M.D., a UB pediatrician.
Among these, she said, are allocation of
available resources, maintenance of confidentiality, privacy for the patient, and duty
co warn third parties.
Some of these issues, notably allocation of
resources, figure prominently in controversies involving other types of disease states,

Nohejl pointed out.
In addition to AIDS, Janek Patel, M.D.,
and Joseph Mylotte, M.D., discussed other
sexually transmitted diseases, notably herpes
and gonorrhea.
Use of oral contraceptives, the IUD, and
changes in sexual behavior since World War
n have led to incr~ases in certain venereal
diseases such as gonorrhea, genital warts, and
genital herpes, they noted.
Patel told the audience that the drug, acyclovir (Zovirax), has proved useful as a treatment for patients who suffer from initial
outbreaks and recurrences of genital herpes
caused by either Type l or Type II herpes
simplex virus. The drug, he cautioned, should
be given for no more than six months at a
time in chronic cases.
Daniel Amsterdam,
Ph.D., a faculty
member in the Department of Medicine and
the Department of Microbiology who is
based at the Erie County Laboratory, discussed laboracory diagnostic methods for
various sexually transmitted diseases.
Also included in the seminar, which was
offered as part of the coursework for Microbiology 600 and 51 I, were Joseph Kite Jr.,
Ph.D., and Boris Albini, M.D., Department
of Microbiology.
•

$200 ,000 bequest will
provi de scholarship s

M

re than $200,000 will go toward
cholarships for VB medical stuents under the terms of a trust
fund established by a Medical School alumnus.
The University at Buffalo Foundation Inc.
recently received $205,229 from the estate of
Vivian Sampson of Chicago, the widow ofW alter Sampson, a nephew of the late UB alumnus
Walters. Barnes, M.D. Barnes had established
a trust fund for his nephew. The terms of the
trust stipulated that the principal would reve rt
to the Medical School upon the Sampsons'
death if their marriage produced no children.
The UB Foundation has used the money co
establish an endowed account, the income of
which will be used for the scholarships.

Buffalo Physician and Biomedical Scientist

�29

Barnes, an 1892 graduate of UB, left the
University $211,000 upon his death in 1958 at
age 89. That money was used to upgrade facilities in Sherman Hall, and a plaque commemorating Barnes was unveiled in Sherman in
1962.
A native of England, Barnes came to the
United States with his parents in 1877. He had
been affiliated with Mercy Hospital in Chicago
for mor e than 65 years, and had served as a
professor at the Northwestern University Medical School.
•

ADDEO PROT!,;CTI O!I OF' FAE E. RAO!Ct,L
AH •. ERS OJHt •.RECOVER
- l"BALI .Y lSCHE :-\IC RAT m : ;,P.T

MTSP student wins
national scholarship

D

avid J. Altman, a Medical Scientist
Training Program (MSTP) student at
UB, was one of thr ee M. O./Ph. D.
students nationally awarded a Medical Scientist Scholarship worth $14,000 per year and
renewable up to five years.
Mr. Altman, an alumnus of Harvard University, received a letter of commendation for academic excellence for the 1984-85 year. In
addition to his fine scholarship, he has also
been involved in student affairs and in the
orientation program for enter ing students.
MSTP students are different from other medical students in that they can work coward a
M. D./Ph. D. simultaneously, completing both
in six co seven years. This program, started in
1982, was designed to narrow the gap of knowledge and understanding that often separates
highly specia lized scientists from practicing
physicians.
•

Psychiatry unit
changes its name

T

he School of Medicine and Biomedical Sciences is not the only medical
unit at UB that has undergone a name
change. The Department of Psychiatry has
been renamed the Department of Psychiatry
and Behavioral Sciences.
The ratio nale for this is that the department

Buffalo Physicianand BiomedicalScientist

:,:

I

i----1 ___

~

._l

~

I

Q
;&amp;Ii i..._ ______

__

___

_____.

Peter Bloom was one of the exhibi tors in UB's seventh annual Medical Student Research
Forum held in Decembe r .

is the principal unit in the Medical School
responsible for teaching and research in the
behavioral sciences. Three required courses in
behavioral sciences during the preclinical years
are offered, and psychiatry is taught in the
clinica l years.
The faculty consists of both psychiatrists and
psychologists with some individuals, especially
the psychologists, primarily responsible for
teaching courses in the behavioral sciences.
Fur thermore, research interest of faculty include such areas as behavioral aspects of health
and illness, neuroendocrine effects on behavior, and prevention of mental retardation
and mental illness.
Dr. Marvin Herz, chairman of the renamed
department, points out that 23 other medical
school psychiatry departments have already
adopted the new names. These include Stanford, George Washington, Johns Hopkins,
SUNY Stony Brook, and Univers ity of
Texas.

•

Minority students
win Regents awards

T

wo UB minority medical students
have received Regents Health Care
Scholarships in Medicine.
The two students are Lisa King and John W
Smith.
The Regents scholarship program is aimed at
reducing the critical shortage of physicians in
certain areas of New YorkState. It also aims to
expand medical educational opportunities for
underrepresented minority students and economically disadvantaged students.
Scholarship holders receive up to $10,000 a
year during their four years of approved study.
After completion of their professional studies,
they are required to practice in underserved
areas of New York State. The UB students represent two of the 40 medical students selected
Statewide.

•

Late Winter '88

~

�30

HEADACHES
ARE
THEIRSPECIALTIES
The information in chis scorywas compiled by
Clare O'Shea from interviews wich Elliott
Schulman and Greg Tramuca, brochure
information and articles on the Comprehensive Headache Center, and nor.es by Bonnie
Schulman and by Bruce Kershner.

W

hile at UB in the mid-60's, a
couple of undergraduates met
playing pinochle in the old Norton Hall. Twenty-five years later, they're
meeting regularly again. But this time, it's to
talk about headaches.
Elliott A. Schulman, a neurologist, and
G regory J. Tramuta, a psychiatrist, are cofounde rs of the Comprehensive Headache
Cente r at The Germantown Hospital and
Medical Center in Philadelphia. The center
diagnoses and treats patients suffering from
one of mankind's most common ailments.
The shift from a pinochle team to a headache team was not exactly planned. Schulman and Tramuta were buddies all the way
t hrough medical school unt il their graduat ion in 1974. But then Schulman moved to
Pittsburgh, Tramu t a moved to Philadelphia,
and eight years went by without any contact
between them .
Then came the day Tramuta was making
h is rounds at Philadelph ia's Germantown
Hosp ital. It just happened to be the same day
and the same hospital in which Schu lman
was making rounds, covering for another
doctor.
"It was totally serendipitous," said Tram uta, now chief of psychiatry at Germantown and a clinical assistant professor at
Temp le University Medical School. " Here
was someone out of my past - I had not
heard from Elliott in years. I was very
surprised."
ln the years since he had last seen Schulman, T r amuta had completed postgraduate
training and a residency at the Albe rt Ein-

Lare Winter '88

stein Medical Center. He had held various
positions including assistant professor of
psychiat ry at the Medical College of Pennsylvania, psychiatric consultant at Germantown and at Wissahic kon Hospital, and psychiatrist at the Fox Chase Cance r Center,
where he worked with terminally ill patients
and their families.
It was at Fox Chase, where he served as
chairman of the pain management committee, that Tramuta became interes ted in
chronic pain. He began discussing wit h Ge rmantown's chief of neurology, Stephen D.
Silberstein, the idea of developing a center
where patients with chronic pain could
receive multidisciplinary treatment.
Schulman arrived in Philadelphia by way
of Pittsburgh and Washington, D .C. Afte r an
internship at Montefiore Hospital, an affiliate of the University of Pittsburgh, Schulman served as a resident at Georgetown Univeristy School of Medicine and a fellow at the
National Institutes of Health. He was subsequently appointed staff neurologist at Temple University Hospital and assistant professor at Temple Univers ity School of Medicine.
Currently, Schulman is an attending neurologist at Germantown and is in private practice with Silberstein.

T

he pain cente r idea surfaced again when
Schulman and Tramu t a began p r ivate
practices. Because of the overlap between
neurology and psychiatry, the two friends
were t reating some of the same pat ients,
shuffling them back and forth between their
offices, then discussing them by mail.
Rather than tryi ng to provide service for
the whole spectrum of chronic pain problems, however, Tramuta and Schulman
decided to establish a multidisciplina ry cente r focusi ng on a manageable segment of pain
sufferers.
In 1982, the two medical school friends .

Buffalo Physicianand BiomedicalScientist

�31

along with Silbe rstein and two psychologists,
Ronald Kaiser and Joseph Primavera Ill,
founded the Comprehensive Headache Center. The center, which meets once a week at
Germantown, now includes a social worker
and three nurse practitioners.
"We knew that we could handle the head
and facial pain populations within our disciplines," Tramuta explained. "We think we
do a lot better than the primary sole practitioner can for patients with chronic pain
problems."
"This is a comprehensive approach,"
Schulman added. "Now that we are working
side by side, we can address the problems as
they come. We don't have to communicate
by mail."
The center is able to treat patients more
effectively and efficiently because of the
accumulated experience and expertise of the
staff. In addition, opportunities for specialized research are made easier in such a setting.
There are about 15 such centers in the
United States. Of these, the Comprehensive
Headache Center is one of only three with an
inpatient unit, according to Schulman. It
remains the only center of its kind in the
tri-state area of Pennsylvania, New Jersey,
and Delaware.
The medical team cannot promise miracle
cures, but they can in many cases help reduce
the frequency and intensity of their patients'
headaches, the two US-educated physicians
agree.
"ln the past, headache sufferers were never
taken seriously," Schulman said. "It was the
classic case of'take two aspirins and call me
in the morning.' We now know there are
treatment plans that really work."

W

hen the headache sufferer first contacts the center for help, he or she is
given an extensive questionnaire to complete
and bring to the initial appointment.
The patient is given a complete medical
exam and is seen by a psychologist or psychiatrist. A psychological profile of the patient
is created using the information provided on
the headache history along with psychological tests . That profile is given to a staff neurologist. A t reatment p rogr am tailored to the

Buffalo Physician and Biomedical Scientist

individual headache patient is then designed
by the medical team.
Treatment will vary, but it may include a
change in diet, medication, behavior modification, biofeedback, and psychological and
physical therapies. Some of the newer medicines used by the headache center include
calcium channel blockers, various antidepressants, beta-blockers and DHE ( dihydroergotamine), an ergot preparation. The
center has been involved in testing a nonsteroidal anti-inflammatory agent, and a new
selective beta-blocker, Schulman said, and
has experimented with low doses of anaprox,
a motrin-relative .
Those patients in need of inpatient evaluation are taken off all unnecessary medications and, in some cases, given a prophylactic
medicine during a five- or six-day hospital
stay. Classes are given on headache types,
drug therapy, and the social ramifications of
headaches. A social worker meets with the
patient and family several times during the
hospital stay.

M

any headache patients have suffered
every day for years without finding
relief from pain.
"lt would not be unusual for us to treat a
person who has suffered with headaches for
over 25 years, often on a daily basis,"
Schulman noted. "These patients commonly
ingest l Oto 12 aspirin or Tylenol daily, along
with an assortment of narcotics and ergot
preparations."
"Because we're really a referral center, we
tend to see people with more severe problems," Tramuta added. "These are people
with severe headaches, people who daily are
taking large amounts of analgesics, tranquilizers, sleeping pills, or specific migraine
medications. They're a wide mix of personalities; some are depressed or neurotic, others
are not.''
The physical pain frequently affects other
aspects of the patient's life.
"Severe depression is a common manifestation," Schulman pointed out. "Patients
miss school or work, have problems with
their families, don't go out.''
' 'T hey are socially isolated because of their

Late Winter '88

�32

headaches," T ramuta added. "Chronic headache pain wears people down. They feel
depressed in response to the pain, and frustrated because they can't get rid of it and
don't understand why they get it. The pain
and the depression can feed on themselves it's a vicious cycle."

J

ust as there is no one patient that is typical, there is no such thing as a typical
headache, Schulman and T ramuta point out.
There are many misconceptions about the
cause of headache pain. Some people blame
their sinus problems. Although sinuses can
ache, the headache in the area of the sinuses
described by most people is rarely caused by
congested or inflamed sinuses. It is more
often the pain of a tension or migraine
headache.
Neither are headaches usually a sign of
high blood pressure, allergies, dental problems, or eye problems, according to Schulman. Some sufferers of severe or chronic
headaches fear the possibility of a brain
tumor. Actually, fewer than 10 per cent of
chronic recurring headaches have such a
serious underlying cause as brain tumor,
blood clot, infection, or hemorrhage, he said.
It is now believed that many headaches
may result from a biochemical imbalance in
the brain, according to Schulman. This
involves the compound serotonin which may
lead to inflammation of the blood vessels and
irritation of the nerves, resulting in a headache.
The imbalance can be triggered or aggravated by many agents, including head injury,
emotional or physical stress, hormonal
changes, drugs, sleep disturbances, noise,
bright lights, weather changes, odors ( including certain perfumes), menstruation, lack of
adequate exercise, alcohol (especially red
wine), large amounts of caffeine, and certain
foods such as bananas, nuts, aged cheeses,
chocolate, smoked or pickled meats, pickled
herring or chicken livers.
"Not every headache problem is headacheinduced," Tramuta pointed out. "People
should take a close look at their environments.''

The most common

Lare-Wimer '88

types of headaches

treated at the center are migraine, tension,
cluster, and rebound.
Migraine and tension are the two major
types of benign chronic recurring headaches.
Since symptoms of each can overlap, however, it has been suggested that migraine and
tension are not two distinct headache types
but rather exist at opposite ends of the same
spectrum.
A bout 20 per cent of the population suffer
from chronic, recurring headaches, Schulman said, although almost everyone suffers a
headache at some time in his or her life.
"More women than men get headaches,"
he added. "And while more women get
migraines, more men get cluster headaches."
The tension headache is typically a dull,
constant ache which usually affects the
whole head. Sufferers often describe the pain
as a tight band around the head, often
accompanied by a tightness in the neck, dizziness or nausea. Aspirin or acetaminophen
often quickly relieves the pain, although it
may last for hours or even days.
The common migraine pain is usually
throbbing, periodic, and one-sided, although
it can be bilateral. Often there is a family
history of this type of headache, which also
can last for hours or days. Nausea or vomiting, sensitivity to light and loud noises,
abdominal pain, anxiety, and fever are possible symptoms.
The classic migraine may bring the same
symptoms, plus it may be signaled by flashing bright lights before the eyes lasting as long
as 20 minutes. In rare cases, weakness or
numbness in parts of the body or blackout in
a part of the visual field accompanies the
migraine. Interestingly, a headache need not
be part of the symptoms of a migraine.
If taken early enough, aspirin or acetaminophen or other prescription drugs can sometimes relieve migraine pain. Drug therapy
may be necessary, however, if the migraine is
chronic.
The cluster headache occurs in bunches
from one to five times a day over a period of
days or weeks, followed by a remission of six
months to a year or longer. Attacks last from
15 to 90 minutes, and recur at approximately
the same time every day, often interrupting

Buffalo Physician and Biomedical Scientist

�33

the person's sleep. The pain always affects
one side of the head, is located around the
eye, and is described as a severe, boring sensation, like a hot poker is being pushed into
the eye. Nasal stuffiness and eye tearing on
the same side as the pain are usual symptoms.
There are no warning signs associated with
the cluster headache, although alcohol frequently brings on che attacks. Cluster headaches are not inherited.
The analgesic rebound is a newly described
form of headache. The first thing many people do when a headache hits is to reach for the
aspirin bottle, or maybe a strong cup of coffee. And they keep reaching, perhaps taking
more than 14 tablets a week or more than
100 a month. It has been shown that such
abuse of analgesics can perpetuate and worsen
the headache pain. And when the medication
is withdrawn, the result is a rebound headache which increases in intensity and lasts
from four days to one or two weeks.
Finally, there is the headache which com-

Stress seen as
primary cause of
children's headaches

S

tress brought on by social or family
pressure is the cause of the vast majority of all headaches experienced by
child ren and adolescents.
"Headaches are very common throughout
all pediatric age groups," said Michael E.
Cohen, M.D., speaking at the Annual Meeting of the American Academy of Pediatrics
(AAP) in November. Dr. Cohen added,
though, that toddlers and children between
the ages of 5 and 15 years have the greatest
incidence of headaches.
Peer pressure, school phobia and family
problems such as d ivorce are some of the
env ironmental facto rs that can cause stressrel ated headaches in children, Dr. Cohen
said. Tension headaches also may develop,
he said, as a result of difficulties with sibli ngs
or when children have problems achieving
their parents' expectations.

Buffalo Physician and Biomedical Scientist

manly occurs as part of the post-traumatic
syndrome chat follows a head injury.
Such a headache can have one or several of
the symptoms of either migraine or tension
headaches.

M

ore than 300 headache sufferers have
been treated at the Comprehensive
Headache Center since it opened its doors.
The success rate has been about 80 per cent,
Schu lm an said, due in large part to drug therapy and the addressing of psychological
issues.
"We have treated patients as far away as
Florida and the Midwest," Schulman said.
''Our youngest patient was 12; the oldest was
80."
"We'll get people who sometimes have
had headaches for years, who feel wretched,
miserable, hopeless," T ramuta said. "They've
been told they have to live with this pa in
which has disrupted thei r who le lives. It's
very gratifying to see people walk out the
door feeling a new optimism about life." •

Dr. Cohen, professor of neurology and
pediatrics at UB, and director of child! neurology, Children's Hospital of Buffalo,
explained that stress-related headaches are
non-migrainous and can occur frequently or
infrequently. He estimated that about 40 per
cent of all children have expe rienced such
headaches by age seven and about 70 per cent
of all children experience th em by adolescence.
Medication may help reduce some of the
symptoms of a non-migrainous headache;
however, Dr. Cohen said that counseling
with a pediatrician, child neurologist, or
child psychiatrist may be a better alternative.
"Counseling of the parents can also be quite
helpful," he added.
Dr. Cohen estimated that the minority of
childhood headaches are caused by physiological problems, such as chronic infections,
brain tumors, or blood vessel abnorma liti es.
He also noted that sinus problems, visual
difficulties and sensitivity to chemicals in
certa in foods are often suspected but seldom
proven as causes of chronic headaches.
•

Dr. John \V. Cudmore

John W. Cudmore (M'62 ), a physician with
Health Care Plan's (HCP) group practice, was
recently promoted to Brigadier General, Army
National Guard. He is a clinical associate professor of surgery at UB.
Cudmore, who received his first commission
in the National Guard in 1963, is in charge of
6,500 troops throughout New York Sta te.
"What is unusual about my assignment,"
Cudmore said, " is that a medical officer has
been given command of general service
troops."
During his years of military service, Cudmore has given many more hours than the
standard two weeks per year and one weekend
per month required for reserve service personnel. He has been called in to assist with floods
and blizzards and the prison uprising at Attica
Sate Penitentiary and to command Military
Medical Support to the 1980 Winter Olympic
Games in Lake Placid.
"l wouldn't do this ifl didn't really enjoy it,"
the general said.
In his new command, Cudmore will oversee
the training of New York State's National
Guard and will be responsible for the level of
readiness sustained among his troops. The National Guard maintains a force that is prepared
to respond to any state or federal emergency
that should arise.
Cudmore, who has been a full-time member
of Health Care Plan's physician staff for five
years, is a genera l surgeon and a staff member
of Buffalo General Hospital.
•

Late Winter '88

�34

William S. Edgecomb '47

1940's
William S. Edgecomb (M' 47 ) •
has been appointed a life fellow of
the American Psychiatric Association in honor of his long-time
contribution to the medical and
general community. Dr. Edgecomb has a private practice in Orchard Park, N. Y., and is currently
an assistant clinical professor in
the UB Psychiatry Department
and president of the medical staff
ac Bry-Lin Hospitals.

1950's
Patri cia A. Meyer (M'50) •
writes, "I would like t0 cell you of
my good fortune. I entered the
February comest of the Monthly
Prescribing Reference and was
the winner of a trip to London on
che Concorde. Along with the
trip, there is a gift of $1,500 for
other expenses."

1960's
Loui s Trachtman ( M'65 ) •
has been elected president of
Eta Chapter (Tu lane University)
of the Delta Omega Society, a
national public health honorary

Late Winter '88

soc iety . Dr. T rachtman is comedical director of the State
Office of Preventive and Public
Health Services and a clinical
instructor at Louisiana State
University School of Medicine.
He is also continuing as assistant
adjunct professor ac Tulan e
University School of Public
Health and Tropical Medicine
and has a pare-time pediatric
practice. Dr. Trachtman has
published numerous articles in
che]ournal of the Louisiana Seate
Medical Society.
Raymond A. Martin (M '68 )
• writing from Houston, Texas,
tells us that he is president of the
Texas Neurological Society for
1987-1988. He is an instructor
in neurology at the University
of Texas .

1970's
Ar thu r M. Seigel (M'7 0) • assistant clinical professor of neurology and pediatrics at Yale
University School of Medicine,
writes that in 1987 he published
"The Neurological Examination"
in PhysicalDiagnosis.Dr. Seigel is
a member of the Board of Directors, New Haven Individual Practice Association.
Richard J. Goldberg (M'74) •
was appointed chief of psychiatry
at Rhode Island Hospital and
Women's and Infant's Hospital in
Providence. Dr. Goldberg is an
associate professor in the Department of Psychiatry and Human
Behavior at Brown University.
Richard S. Elman (M'78) •
has been named medical director of the emergency department at Sisters of Charity Hospital. Dr. Elman, who assumed

years of practice in general internal medicine at Harvard Community Health
Plan,
Dr.
RockwelI is now a firsc-yearfellow
in endocrinology at Beth Israel
Hospital, Boston, Mass. Dr.
Jederlinic is an assistant professor
of medicine: critical care, pulmonary and occupational medicine,
at the University of Massachusetts-Worcester.

Richard S. Elman '78
his duties on September 1, is the
only board certified emergency
medicine physician in the Buffalo area.
A magna cum laude graduate
of Case Western Reserve University, Dr. Elman, after receiving his UB med ical degree,
completed an internship in family practice at University of
Arizona Affiliated Hospitals.
Prior to joining the Sisters staff
he was director of emergency
services at Lockport Memorial
Hospital.
Paul Summ ergrad (M'78) •
writes, "I have been appointed director of che inpatient psychiatric
service at Massachusetts General
Hospital. where I completed my
psychiatric residency in 1985. I
also completed a residency in internal medicine at Boston City
Hospital in 1981. I am board certified in internal medicine and
psychiatry."

1980's
Peter Jederlin ic (M' 79) and his
wife Jessica Rockwell (M'82) •
inform us that they have two children: Nicole Sarah and Alex
Michael. After completing cwo

Robert A. Herman (M' 83) • recently completed his residency in
psychiatry ac NYU School of
Medicine and opened his private
office for the practice of psychiatry at 35 West 90th Street, Suite
lA, New York, N. Y. 10024. He
has been accepted as a candidate
at the Columbia University Center for Psychoanalytic Training
and Research. Dr. Herman is a
clinical instructor at NYU and is
assistant clinical psychiatrist ac
Bellevue Hospital.
Patricia Flanagan (M'83) and
Mark Schwager, (M'83) • of
Cumberland, R.I., joyously announce their new arrival, Zachary
Alexander, born July 8, 1987.
Herbert B. Newton (M'84) • informs us chat he has been accepted for a fellowship in neurooncology at Memorial Sloan-Kettering Cancer Center in New
YorkCity. He is planning to publish a paper on che effects of
cisplatin in che treatment of malignant brain tumors.
Blackford Middleton (M' 8 5) •
writes, "Mose exciting news is of
marriage co Ursula G. King in
September. After chat I am happy
co report that I marched for my
first choice fellowship position
which will be at Stanford Unive rsity as a fellow in General Medicine and Medical Informatics!"

Buffalo Physician and Biomedical Scientist

�35

The Batavia VAMC

Batavia VAMC joins
UB affiliate group

A

s if eight affiliated teaching hospitals
weren't enough, the UB Medical
School has added one more : the
Batavia Veterans Administration Medical Center (V AMC). The addition extends UB's educational mission not only to Batavia, 30 miles
east ofBuffalo, but into Rochester as well. This
is because Batavia V AMC has an outpatient
clinic in Rochester. Batavia V AMC is UB's first
teaching hospital outside Erie County.
"We are pleased at the opportunity to extend
our work with the Veterans Administration to
facilitate development of education and research in geriatrics and rehabilitation," Vice
President and DeanJ ohn Naughton comments.
"We see Batavia VAMC as accelerating the
school's ability to strengthen its role as a national leader in geriatrics and rehabilitation."
Specifically, the new affiliation provides an
alternative environment for training students,
residents, and fellows in geriat rics and rehabilitation medicine. It will also stimulate
resea rch activity in these disciplines as well as
in long-term care and home care.
For the hospital, it will provide a more
focused mission in these areas. It will also help

Buffalo Physician and Biomedical Scientist

the care of veterans by bringing the University
in contact with the hosptial, and enabling the
staff to be enriched. All hospital appointments
in the future will become UB appointments.
Batavia V AMC previously had an educational linkage with the University of Rocheste r. That affiliation was dropped after a review
indicated chat the hospital's interests complemented UB's strengths.
The reporting relationship of veterans hospitals in Batavia and Buffalo will remain independent. Neither one will have a subordinate
role regarding UB and both will sit on the same
dean's committees.

•

State proposal would
limit residents' hours

A

proposal
before State Health
Commissioner
David Axel r od
would limit resident physicians
throughout the State to working no more
than 80 hours a week.
The report from the Ad Hoc Adviso ry
Commit tee on Emergency Services, chaired
by Dr . Bertrand M. Bell, also recommends
that non-emergency room residents be scheduled to work for no more than 24 hou rs in a
row. They must be off for one 24-hour

period a week.
An ear lier proposal had recommended
that residents work no more than 16 hours in
a row.
Residents in emergency rooms would be
limited to working 12 hours in a row, which
is already standard practice, said John
Naugh ton, dean of the UB School of Medicine and Biomedica l Sciences and vice president for clinical affiars.
An individual who has worked the maximum number of hours as a resident won't be
allowed to work additional hours as a physician in another hospital.
The proposal also requires that hospitals
provide more ancillary care to make up for
the decreased workload of house officers .
Hospitals must have sufficient IV services,
phlebotomy services, and messenger/transporter services to meet the new demands, the
committee's report says.
All of the recommendations are based on
the understanding chat the Department of
Health will provide the necessary funds to
implement the recommendations; according
to the report.
•

U.S. Army contract
at Roswell Park

T

he United States Army and Roswell
Park Memorial Institute have entered
into a th ree-year, $488,379 contra ct
co develop and test more effective, less toxic
interferon inducers to prevent and treat viral
diseases. The contract was announced by Dr.
David Axelrod, New York State commissione r
of health, and Dr. Thomas B. Tomasi, director
of Roswell Park.
Interferon is a natural protein that cells produce when attacked by a virus in order to "interfere" with the reproduction ~f the virus in the
body. Interferon inducers are synthetic mate•
rials chat are injected into the patient to scimu•
lace che body to produce its own interferon.
Dr. Judith A. O'Malley, director of biological resources, and Dr. Jake Bello, principal
cancer research scientist in che Roswell Biophysics Department, are the co-principal investigators on the contract.
•

Late Winter '88

�36

Dr. Ko rn el Lud wig Terplan • 93, former
chairman of the pathology department at the
University of Buffalo School of Medicine,
died Nov. 21 ar his new home in Sonoma,
Calif.
He taught two generations of medical students and was renowned for his studies of
children's brain development.
Dr. Terplan, a native of what then was the
Austro-Hungarian Empire, had lived in Buffalo from 1930 to last June and had continued his brain research and part-time teaching until last year.
A tall man described as formal and private,
but noble, by one of his former students, Dr.
Terplan was said to have been an inspiring
teacher as well as a renowned medical researcher.
His description, released in 1932, of body
changes during insulin shock is said to have
been the first report of its kind. His pediatric
brain collection, called one of the world's
best, was transferred last year to the UB
School of Medicine, where it is used in reaching medical students. He lectured widely on
pathology ro medical groups.
Born in Aranyosmaror, Hungary, Dr. Terplan was raised in Schessburg, a German
Lutheran enclave in the Transylvania part of
Hungary. He studied medicine in Budapest
and Prague and served during World War l
as a medical officer in the Austro-Hungarian
Army. He graduated in 1919 from the German University of Prague and did research
there until 1930 when he was asked co come
to the UB School of Medicine and Buffalo
General Hospital.
He began here as a research professor in
pathology and in 1934 was appointed the
department chairman. He is credited with
developing UB's modern pathology department.
After he retired from UB in 1960 and was
appointed professor emeritus, Dr. Terplan
continued his research under grants from the
National Institutes of Health.
He maintained an office in Children's
Hospital until shortly before he moved to
California. He belonged to the Buffalo
Athletic Club, where he regularly swam until
about a year ago.
Survivors include his wife, lnge; three

Late Winter '88

sons, Dr. Martin of Sausalito, Calif., Dr.
Peter of Los Angeles and Dr. Fritz of San
Francisco, and three grandchildren.
(Reprinted from the BUFFALONEWS)

Frank Chambers (M'40) of Plant City, Florida, died July 13, 1987. Dr. Chambers had a
family practice in Plant City for 36 years. He
was a member of the American Family Practitioners and a Federal Aviation Authority medical examiner. He was a veteran of WW II,
having served in the Navy as a pilot. He is
survived by his wife Elizabeth Bateman Chambers; two daughters, Mrs. Pamela McGinnes
and Mrs. Sherrie Mueller, and a son, Dr. Step•
hen F. Chambers, all of Plant City.
Milton A. Palmer (M'27) of Lancaster, New
York, died March 30, 1987. Dr. Palmer was a
life member, incorporator, and charter member
of the board of directors of the Bufflao EyeBank and Research Society. He was chairman
of its executive committee for 10 years, president for 21 years, and was president emeritus .
Dr. Palmer was a life member of the Eye-Bank
Association of America, and in 1983 he received the Rudy Spitzer Memorial Award for
Sight Preservation and Dedicated Participation
in the Buffalo Eye-Bank and Research Society.
He is survived by his wife, Doris Wheeler Palmer, and a son, William W.
•
Walter Stafford, Jr. (M'44), a UB physician
who once also served as a special assistant to the
acting president ofUB, died August 12, 1987,
at age 67. He held several faculty titles, includ ing clinical associate professor of neurology,
clinical associate in anatomy, and a former title
with the Pathology Department. He was a neurologist on staff at BuffaloGeneral Hospital for
more than 30 years. Dr. Stafford served with
the U.S. Navy in the Philippines during World
War II. An accomplished pilot, he once conducted research at Cornell into the effects of
high speed flight on the human body.
•
Dr. John Charles Robin, 38, a second-year
student at the UB School of Medicine, died
September 2, 1987.
A lifelong Buffalo resident, Robin had suffered leukemia for about two months.
He held a degree in psychology, a master's

degree in natural sciences and a doctorate in
pathology, all from UB.
Robin was a member of the Erie County
Historic Preservation Board, the Allentown
Association and the University Club.
Survivors include his parents and four
brothers.
•
Norman S. Ellerstei n (M'71), known for his
work on the detection and prevention of child
abuse, died August 25, 1987 in Amherst after a
long illness.
He held various positions at Children's Hospital and was an assistant professor of pediatrics
at UB's Medical School.
Born in Akron, Ohio, Dr. Ellerstein was
raised in Buffalo. He earned his undergraduate
and medical degrees at UB.
Dr. Ellerscein was a full-time staff member
and held several administrative positions at
Children's Hospital.
He was director of the Child Abuse and
Neglect Program, run jointly by UB and the
hospital, and was director of the hospita l's
Child Protection Clinic and of the pediatric
house staff program.
A fellow of che American Academy of Pediatrics, Dr. Ellerstein wrote many articles and
books on pediatric medicine and child abuse
and neglect. He was an editorial consultant to
many professional and medical journals.
Surviving are his wife, a son, and his
mother.
•

A lfre d Mi tchell (M'38) • died on June 20,
1987, in Elmira, New York . Or. Mitchell
practiced internal medicine in Elmira, from
1940 co 1987. He was a Diplomat of the
Board of Internal Medicine.
Elme r G r ob e n (M'4 1) • died Septembe r 5,
1987, after an extended illness. He practiced
medicine in Columbus Junction from 194 7
co 1970 when he moved to Iowa City where
he practiced until 1983. Or. Groben was an
associate professor in family practice at the
University of Lowa College of Medicine. He
is survived by his wife Martha and two sons
and cwo daughters.

Robert Wa rd ( M'47) • died on November
25, 1987, in Miami, Florida.

Buffalo Physicianand Biomedical Scientist

�SPRING
CLINICAL
DAY AND
REUNION
WEEKEND

May 7, 1988
Buffalo Marri ott
8: 15 , Morning Scientific Session
12:30: CONTROVERS IES AND
TREATMENT OF AIDS, BREAST
CANCER AND CORONARY
ARTERY DISEASE

1 :00:

Stockton Kimball Memorial
Luncheon and Lecture
Honored Leaurer

ROBERT P. GALE, M.D. '70
Associate Professor of Medicine,
UCLA Medical School

Dr. Roberr Gale

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Address Correction Requested

MEDICALHISTORICALLIB,
KtMSALLTOWER,SERIALS DEPT,
MAINsr . CA'&lt;IPUS
BUFFA~O NY

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142\ ◄

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LETUS HEARFROM YOU

Fill out this card
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�</text>
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                    <text>Vol 22, No

~

�Dear Alumniand Friends:

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Features
The best is yet to come. Donald S. Faber, Ph.D .,
received the prestigious Javits Neuroscience Investigator Award for his work that has helped
change the way we think about the nervous
system .

I

lucky13. For alumnus Larry Schreiber and his wife,
Carol, ten adopted children plus three children by
birth add up to one big happy family.
Cholesterol.Can you trust laboratory measurements of cholesterol levels?An October conference
looked at that and other question s pertaining to
cholesterol.

I

Passivevaccine.Edwin D. Kilbourne, M .D., one of
the world's leading experts on influenza, is working on an influenza vaccine that actually allows
a virus to invade the body . He described his
research in the fall Harrington Lecture .
Airwaves.Three students find that jobs as radio
disc jockeys ease the tension of medical school.

~

Handpicked
. The students entering UB's medical
school are talented and diverse.

Departments
HospitalNews.The board of managers at the Erie
County Medical Center has more power over the
day-to-day operations of the hospital, thanks to
a new law that was effective Jan. l.
Classnotesand alumninews. A new annual award
will honor a Distinguished Medica l Alumnus/a .

Cover P hoto: Bob Walion

��3

It's More Than Electrical Wiring
Faber gets ]avits Award
for researchon nervous system

i

f

ver the last 14 years, Donald S.
Faber, Ph.D. has he lped change
the way we think about the nervous system .
In recogn ition of that fruitful work,
and in anticipation of more to come, the
UB professor of physiology has been
given the prestigious Javits Neuroscience
Investigator Award by the National Institute of Ne u rologica l and Communicative Disorders and Stroke .
The award, named for the late Sen .
Jacob K. Javits of New York, is given to
investigators who have a distinguished
record of substantia l contrib utions in
neurologica l or comm u nicative sciences
and who can be expected to be highly
productive over the next seven years.
The award grants Faber an extra two
years of funding for his new NIH grant,
bringing it to a total of $1.2 million over
seven years.
Since the 1970s, Faber and the
members of his laboratory have collaborated closely with a group of
researchers, led by Henri Korn, M.0.,
Ph.D., at the Pasteur Institute in France .
"The award is the result of our collaborative efforts;' Faber said .
This grant, as well as h is previous
work, focuses on synaptic interactions in
the central nervous system.
Faber and his colleagues work with the
Mauthner cell in the brain of a goldfish,

BUFFALOPHYSIC IAN AND BIOMEDICALSCIENTIST

which he finds to be a better experimenta l mode l than
mammals
or
invertebrates.
"Ic's a very beautiful system for a
number of reasons," Faber said . "The cell
is identif ied-you can give it a name .
That's not common in other systems.
"There are just two of these Mauthner
cells, one on each side of the brain . And
the cells are large."
The job of the Mauthner cell is to trigger the fish's escape mechanism-when
you tap the aquarium, the fish swims
away. Different kinds of sensory input
trigger the cell and trigger it reliably.
How does this trigger work? Using
microelectrodes, the researchers recorded the Maut hn er cell's responses to inputs from sensory cells and from inhibito ry interneurons (the cells that
"talk" to the Mauthner cell). These inhibitory cells are part of the network that
controls when an escape occurs.
Injecting dyes into the inhibitory intemeu ron, the researchers were able to
look at the structu res of the synapses using the light microscope and electron
microscope .
"By combining physiology and structure, and statistical ana lysis of responses
of the Mauthne r cell to inhibitory intemeurons, we have developed a mode l
at the microscopic level for synaptic
transmission in the central nervous

LATE WINTER 1988-89

�4

Does one synapse
influence another?
"We're excited about
the question of cross
talk because it opens
up a number of possiblr
ua)S

of thinking about

hou the nervous
s, stem i0orks."
1

LATE WINTER 1988-89

system; Faber said. "This mode l is common not just to fish, but to most neural
connections!'
ne aspect of the model is related co
the fact that the endings of nerve
cells release chemical transmitters in a
"probabi listic" way, Faber said . 'There's
a degree of uncertainty in the way the
connections work ."
We often think of the nervous system
as a wiring diagram . If you flick a switch,
a light bulb goes on.
But Faber pictures it this way: You've
got 10 light bulbs . When you flick the
switch, sometimes all 10 bu lbs light up.
Another time just four light up, or none
come on at all. Though the stimulus is
the same, the message that the cells
receive is different each time.
This probabilist ic feature also provides
the basis, in some systems, for forms of
"plasticity" where, with experience,
synaptic connections become reinforced .
For example, if you stimu late a nerve cell
repeatedly, there's a greater chance that
subsequen tly all 10 bu lbs will switch on .
Faber likes to use the term "plasticity" co
describe this phenomenon, preferring
that word over "learning" or "memory~
That, in capsule form, is what Faber
has been working on for 14 years.
About four years ago, Faber and his
colleagues began to think about the u nity of a synapse-not
on ly how the
chemical trigger is released, but how the

Mauthne r cell responds . They've
developed computer models of how that
works, tak ing into account the diffusion
of the chemical transmitter in the synaptic cleft (the very small space between the
inh ibitory
interneuron
and the
Mauthner cell) and how the Mauthner
cell responds to that transmitter .
T his mode l prompted the researchers
to become interested in new questions,
including : Are the adjacent synapses
isolated from each othe r or does one
synapse influence another?
The re are indeed mechanisms for cross
talk between adjacent synapses, Faber
and Korn wrote in a November 1988 article in the Proceedingsof the National
Academy of Science.This work becomes
the focus of the Javits Award, Faber
explained.
"We're excited about the question of
cross talk because it opens up a numbe r
of possible ways of thinking about how
the nervous system works:• he said .
The genera l notion about a synapse is
chat a chemical neurot ransmitter is
released, diffuses over the synapt ic cleft,
binds to specific receptors on the other
side, and is quickly deactivated when
Pac-Man-like proteins gobble it up or
carry it away.
But Faber has found that instead of being active ly carted away, the chemical
transm itter slowly diffuses away. While
the chemical lingers, its effect can be
compounded . For instance, if two adja-

BUFFALO PHYSICIAN AND BIOMEDICAL SCIENTIST

�5

Faber thinks a
chemical transmitter
can change an
adjacent receptor site.
"If iue're right, we
have a tremendous
mechanism for
modulation of synapses
that use even different
transmz.tters.''

cent inhibitory incemeurons transmit
glycine, the effect is greater than the two
individua l effects added up.
"The fun thing we want to do in the
next few years is expand chat concept;'
Faber said.
Suppose two adjacent nerve endings,
called A and B, release different chemica l
transmitters onto one cell. In the old way
of thinking, chose nerve endings are
isolated from each ocher. Chemical A affects receptor site A and Chemica l B affects receptor site B. Then the chemica ls
are quickly deactivated.
But Faber thinks it's possible that
chemical A may affect not only receptor site A, but diffuse over to receptor
site B and change it as well.
"If we're right, we have a tremendous
mechanism for modulation of synapses
that use even different transmitters;' he
said . This adds a level of sophisitication
to our thinking that's left out of the "wiring diagram" view of the nervous system.
He noted that a lot of experimenta l
models for plasticity in the nervous
system on ly work when groups of cells
are active, not when a sing le cell is active . Faber's postulation "is one type of
mechanism that explains chat, we hope .
We'll try to find our:•
aber received his S.B. in electrical
engineering from the Massachusetts
Institute of Technology and his Ph .D. in
physiology from UB in 1968. For cwo

BUFFALO PHYSICIAN AND BIO MEDICAL SCIENTIST

years he worked ac UB as a postdoctora l
research fellow supported by an NIH
grant .
He left UB to become a visiting
research associate at the Max Planck Institute for Brain Research in West Germany, chen moved on to a similar position ac the Universice de Paris.
From 1972 to 1974 he was an assistant
professor of physio logy at the University of Cincinnati.
Faber moved back co Buffalo co cake
a position as a research scientist with the
Research Institute on Alcoho lism. In
1975 he joined che faculty at UB and in
1978 became director of the Division of
Neurobiology, a pose he held until 1986.
A prolific writer, Faber has published
82 papers and one book. In addition, he
holds numerous positions with faculty
committees.
Awards are nothing new to Faber. He
was an exchange scholar with the
Capital Institute of Medicine in Beijing
in 1986, a fellow of the Neuroscience Institute in New York City in 1984, a fellow
of the Claude Bernard Association in
Paris in 1972, and a Grass Foundation
fellow at the Marine
Bio logical
Laboratory in Woods Hole, Mass. in
1969.
About the Javics Award, Faber says
modestly, "It's a nice feeling to be
recognized . le says my colleagues like
what we've been doing:'
•
LATE WINTER 1988-89

�0

Il.§

6

LATEWINTER1988-&lt;W

0

ceil.Ir

BUFFALO PHYSICIAN AND BIOMEDICAL SCIENTIST

�7

Larry and Carol
Schreiber, the jay of adoption has evolved into a
lifetime pursuit. They have
adopted 10 children- nine in
seven years - in addition to their
three children by birth. In the rural
town of San Cristobal, New Mexico, population 200, the Schreibers
and their 13 children comprise 5.5
per cent of the total population.
Their experiences have been so
good, they have formed a non-profit
organizationcalledChild-RiteIncorporated to help place other children
with special needs.
The couple's interest in adoption
began in Buffalo in 1971 while
Larry Schreiber, a UB medical
schoolalumnus (M'72), was on his
senior pediatric rotation at Buffalo
Children's Hospital and Carol was
there as a recreationaltherapist. It
was there that they met Lawrence,
a 17-year-oldhemophiliac.
or

BUFFALOPHYSICIANAND BIOMEDICALSCIENTIST

LATE WINTER 1988-89

�8

awrence "was having various
medical, financial, and family problems at the time and cou ldn't
return home to his family in New
York City. He needed a temporary place to stay while he
was being treated in Buffalo;' Schreiber
explains. "Carol and 1,having worked extensively with him during his treatment
ar the hospital, were concerned for him.
So, we offered him our place to stay:'
After 10 months he was able co return
successfully to his own family. Now 29,
Lawrence resides in Buffalo with his wife
and three children.
Sho rtl y following Schreiber's graduation from medical school, the coup le
moved to New Mexico where Schreiber
began his summer internship at the
University of New Mexico-affiliated
hospital in Albuquerque.
Working
primarily in the pediatric ward, Schreiber
met a four-year-old boy named Matthew
who had lived in five foster homes after
being abandoned by his mother when he
was only a year old .
Since Matthew had no home or family waiting for him, the Sch reibers
yearned to give him a loving and permanent home, something

he had never yet

experienced in his young life.
ln response co Matthew's needs and
cheir unwavering
emotions,
the
Schreibers
adopted
Matthew
in
December 1972. He was their first child.
Only one month later, Sch reiber
helped Carol deliver Jordan, the first of
three children born to the couple. Lucas,
their second son, was born in July of
1974, and their daughter, Gabrielle, was
born in November 1978.
le was not until 1980 chat the
Schreibers considered adoption again.
Schreiber was working as a volunteer for
the International Red Cross Committee
on the Thai-Cambodian border when he
met Michael in a refugee camp. Michael
was an II-year-old Cambodian orphan
who was subjected to horror of watching
his family of four die at the hands of the
Khmer Rouge. He had been surviving on
his own in the war-torn country for
several years.
Schreiber was moved by Michael's circumstances during his three-month stay
in the refugee camp. Having inadequate
medical facilities to treat a cleft palace
from which Michael was suffering,

LATE WINTER 1988-89

Schreiber wrote to his wife suggesting
Michael's adoption and treatment in the
U.S. Caro l agreed and the Sch reibers applied for Michael's adoption immediately through the United Nations, but there
was extensive polit ical and bureaucratic
red tape.
"The political climate in that region of
the world was very unstable ar rhe rime;
Schreiber recalls, "so Carol and I were extremely worried that Michae l wasn't going to be released from rhe country ."

;\1tcha l arni eel at
L A. International

Airport not knoi i g
an'\ En lish, Just
tearing a tag around
hii; neck that identifze
his famzh and
destination Wzthin

u eek,, bab'\/
Yo Ri chaperoned
tu o

from Korea, arrned
zn the U.S.
Feeling frustrated and helpless, the
couple sought advice and emotional support from Friends of Children of Various
Nations, an adoption agency based in
Denver. Here they became interested in
a nine-month-old girl from Korea named
Yo Ri. The Schre ibers were first introduced co Yo Ri through "exchange books"
that contain a phorograph and an extensive case history of each child . The
Korean infant was also suffering from a
cleft palate . However, un like Michael's
situation, Korea was politically stable
enough co have her released for che
Schreibers' adoption.

While they were awaiting Yo Ri's arrival, much co the relief of the worrystr icken Schreibers, Michael was finally
released from Cambodia . He arr ived in
June 1981 at L.A. International Airport,
not knowing any English, just wearing
a cag around his neck chat identified his
family and destination in New Mexico.
Within
two weeks of Michael's
homecoming, baby Yo Ri, chaperoned
from Korea, also arrived in the U.S.
"June 1981 was a very excit ing month
for us with the addition of both Yo Ri
and Michael within such a short time;'
recalls Schreiber. "After such elation,
Carol and I had very few reservations
about adoption."
In 1983 che Schreibers again adopted
two children at one time. Eight-year-old
Kevin and his IO-year-old sister, Mary,
came to the Schreibers from southern
New Mexico . The two black children
had only each olher as family after experiencing child-neglect and then several
temporary homes through the foster-care
system . They were a welcomed addition
co the growing Schreiber clan .
Next, in 1986 came Gina - all the way
from Calcutta, Indi a. Gina, on ly eight
years o ld and suffering from polio, was

abandoned because her mother cou ldn't
care for Gina's special needs while caring for Gina 's six sisters. The Schreibers
were informed of Gina's situation
through an Albuquerque adoption agency called Rainbow House. Since joining
the Schreibers, Gina has had back and
leg surgery and is able to walk with the
help of braces.
When Schreiber flew co Calcutta co
escort Gina back to New Mexico, he met
Gina's good friend Champa . Champa
was co be adopted by a family in another
region of New Mexico. In November
1987, Rainbow House called che
Schreibers to tell chem chat Champa's
adoption didn't work out with her prospective family and chat she was going
to return to India. Once again the
Schreibers opened their hearts and their
home and took Champa in.
All of their children are now thriving.
Matthew, 20, from New Mexico, is currently a sophomore at Eastern New Mexico University. Michael, from Cambodia,
is 19 and attends Pitzer College in
California. Jordan, 15, attends Taos
County High School. Champa, from In-

BUFFALO PHYSICIAN AND BIOMEDICAL SCIENTIST

�9

Hen•'s tht whole clan Larn &lt;1nd Mattheu art st&lt;1nclmg m bad,. ln the m1clcllerow, from left ar~ Mary, C hamf&gt;a· Michael;
Re) na1clo bemJ:'hl'lcl 1,..,( arol; I 1cas; Jordan and Ket m. Th girls m front ar Yo Rr, Lorena, Gabriell huJ:'grngC 1ela and Gma

dia, is now 14. After studying English
and the equivalent of eight years of
school in merely three years, she attends
junior high with Lucas, 14, and Mary,
IS, one of the black siblings. Mary's
natural brother, Kevin, 13, attends Taos
Middle School with Gabrielle, 10, and
Gina, 10, from India. And Yo Ri from
Korea, 7, attends Taos Elementary.
chreiber acknowledges that all
has nor been smooth sailing
with such a large and diverse
family. Problems often arise
when another child is added
to the family, especially when a
newly adopted child is the same age as
a child already there.
"It is sometimes a difficult adjustment
for a child who has already been through

BUFFALOPHYSICIAN AND BIOMEDICAL SCIENTIST

four or five foster homes; Schreiber
added. "It takes a little bit of time for a
child to figure out how he fits into the
new environment. But that's only
natural. All the kids have fit in just
beautifully.
"We have family meetings all of the
time, so that grievances and growing
pains are aired before they become too
large to handle. We keep the lines of communication open. When we are considering another adoption we discuss it
among rhe whole family. If anyone is uncomfortable with an addition at a certain time, then we decide against it.
When we do decide to adopt a child, it
is a family decision."
The latest additions to the Schreiber
brood came in the beginning of 1988
with little hesitation from the family.

They are Lorena, 4; Ciela, 3, and
Reynaldo, 2 - three Hispanic siblings
from southern New Mexico. They are
now the youngest of the Schreiber
children .
"Carol and I had never really planned
to adopt ten children, but the addition
of each individual child, with his or her
own diversity of unique personal and
cultural backgrounds, has helped all of
us grow immeasurably closer and
stronger as a family. The tribulations
seem minimal by comparison. We have
found adoption to be the most splendid
thing in our lives; Schreiber emphasized.
The Schreibers say they are now at
"capacity; but their enthusiasm for adoption hasn't waned . They've steered their
efforts coward Child-Rite Incorporated,
a non-profit organization they formed in

LATE WINTER 1988-89

�---:

10

�h
hut

II

un J

hi
orgar

z

ati

Ri
n th

t

I he co plt t mp
li

m~

pro

oft

often n

1986 to help place "special needs
chi ldren" in permanent residences.
"Special needs children" is a term given
by the government for children in state
institutions or foster care who are older
(9 years and up), are in sibling groups,
have minority backgrounds, or have exceptional physica l, mental, and emotional needs. Most special needs children
are placed in state custody or foster care
as a result of child abuse, neglect, or
abandonment.

...

II of the Schreibers' adopted
children were considered
"special needs children" by the
state . The couple emphasizes
that their family is living
proof of the overwhelming joy chat these
often-neg lected children can add to a
family.
They point out chat the wait to adopt
a special needs infant is usually less than
a year, which is much shorter than the
usual three-year wait for healthy white
infants . Also, it is not only possible, but
common, for loving single parents to
adopt a special needs child.
To families who decide to adopt special
needs children, the state may pay a stipend depending on the family's income
and the specific needs of the child,
Schreiber pointed out, but laws vary
BUFFALO PHYSICIAN AND BIOMEDICAL SCIENTIST

l

from state to state . There are also other
subsidies such as food stamps and
Medicare, which may include both
medical and psychiatric treatment for the
adopted children .
Child-Rite has placement and referral
services that are national in scope. It will
refer prospective parents to other agencies and organizations which may better
fulfill the parents' needs. Schreiber
stressed that Child-Rite does not charge
for consultation or referral. Its funding
depends so lely upon private taxdeductible donations.
Child-Rite works closely with Bob
DeBolt and Aid for Adoption of Special
Kids (AASK). DeBolt established AASK
in 1976 to place special needs children
in permanent residences after his family
reached adoptive capacity at 20 children.
Other Child-Rite board members include Carol Schreiber, who is completing
her M.A . in social work at the University of New Mexico, prominent regiona l
artist Veley Vigil, and author John
Nichols, who wrote The MilagroBeanfield
Wars, which Robert Redford recently
brought to the screen.
For more information concerning
adoptions or donations, write to the
Schreibers at Child-Rite Inc., P.O.Box
42, San Cristobal, New Mexico 87564,
or call (505) 776-8158.
•
LATEWINTER 1988-89

�12

TRUSTWOR

7•

Cholesterol tests yield dubious results
hen I was in medical school, I thought
if I sent a sample to the lab, I could
rely on the values," said Philip L.
Green land , MD. "I don't think we feel
that's entirely true any more, especially in
relation to cholesterol testing."
Greenland, an associate professor of
medicine and preventive medicine and director of preventive cardiology at the University of
Rochester, spoke at UB in Octobe r during a conference on "Elevated Cholesterol: A Public Health
Crisis?" sponsored by the UB medical school.
The medical literature points out that laboratory
measurements for cholesterol around the country
aren't very good, Green land said.
He noted that 240 mg/di of cholesterol is considered the cut off for high risk. But if a blood sample that has a value of 240 is sent to a lab it might
come back with a result ranging anywhere from 226
ro 254.
"In other words, you might see a patient today
whose true value is 240 and it comes back 254,"he
said. "You might see him tomorrow and you
measure it again and it comes back 226, and
nothing's happened to the patient; it's simply the
laboratory variability!'
Using the instruments and chemicals they have
today, the laboratory people don't think they can
get more precise than that, he added.
In a 1986study, blood samples were sent to 5,000
labs in the United States. While the true value of
the specimens was 262,95 per cent of the lab results
ranged from 210to 3IO.
That's when peop le started getting excited and
the Wall Street Journal ran an article about it on
the front page, Green land noted.
The problem is with reference materials supplied
by the manufacturer that laboratories use to
calibrate their resting systems. The best reference
material would be blood, but that's coo expensive
co use.
Manufacturers are trying to come up with better references and have improved their products in

LATE WINTER 1988-89

the last several years, Greenland noted . That
resulted in some inadequate tests being pulled off
the market.
Another problem with cholesterol testing is that
several methods are used, but the results aren't comparable. One method might give a result of 225
while another yields a value of 240.
"Laboratory directors are aware of this problem
now and by and large are correcting for it," he said.
G reenland indicated that labs shou ld use a
system that's comparable with one used by the
Centers for Disease Control.
While the CDC standardizes systems, it doesn't
have enough resources to standardize labs, except
for labs conducting NIH-sponsored research.
"To my knowledge, between Rochester and
C leveland, there is no CDC-standardized
laboratory," Greenland said.
"Thank goodness we're in New York because the
State Health Department is developing a reference
lab so that laboratories in the State can send
samples to Albany and assure themselves that they
are giving answers traceable back to the CDC.
"ls that happening now? No. The best thing you
can do is ask your lab director if he's using a system
traceable back to the CDC."
Also ask the lab director for data on the precision and accuracy of his lab, Greenland suggested.
While there are a lot of problems with
cholesterol testing, testing for components of
cholesterol is even worse, Greenland said .
There are several components to cholesterol.
One, called low density lipoprotein or LDL, is connected with a higher risk of heart disease. But
another, high density lipoprocein or HDL, protects
people from heart disease.
While it might be beneficial to know rhe levels
of various components, today's tests don't tell you
much, Greenland said.
Cho lesterol testing "has problems, but it's getting better," he said. He predicted char we'llsee more
specific tests in the future.
The cholesterol levels of most of the people in

BUFFALO PHYSICIAN AND BIOMEDICAL SCIENTIST

....

�...
-..
'

••
, •
•

••

Bad Food
s:
•
•
•••••••

••

••••

cream
► sour cream
► ice cream
► cheeses
► butter
► eggs
► red meat
► sausages
► organ meats
► palm and coconut oil
►

�14

"lf somebody enjoys drinking, I might allow him
two drinks a night . But I wouldn't recommend it
as therapy for a ceecocaler."
There's a whole list of drugs chat can lower
cholesterol, bur all have drawbacks, Kohn said.
Each drug has its own sec of possible side effects.
For instance, Nicotinic Acid can cause flushing,
gastritis, nausea and malaise. You'll feel lousy for
a week, Kohn promised, then these side efects
generally disappear . Nicotinic Acid can also cause
abnormal results on tests of liver function.
The cost can be another drawback. Prescriptions
may run $100 a month. And after a while, a single
drug may be no longer effective and the doctor may
tum to a combination of drugs .
"But when you consider what this costs, the patient may be taking $200 or $300 worth of drugs,"
Kohn noted . "lf the pat ient also happens co have
hypertension or something else, he has $200 more
of that medication. The patient must be very rich,
indeed.
"When you're dealing with real patients, you've
got to be aware of the costs of all these medications
you're ordering or you won't have a very big practice very long."
Kohn says he hopes that new cholesterol drugs
will spark enough competition among drug companies to bring the price down.
"If patients are concerned about the price of
drugs, the only alternative we can offer is diet, and
they will have to modify their behavior and stick
to that diet the rest of their lives," he noted .
But this diet is nor well accepted by Americans,
he added. His point was illustrated by a 27-yearold woman in the audience. Her mother had had
oods to watch out for, Kohn said, include dairy
a stroke, she explained, and she was concerned
foods, eggs, palm and coconut oil, red meats, about her own cholesterol levels. Ac what point
organ meats, and anythingin a sausage casing. Good
would Kohn prescribe medication, she asked, adfoods include poultry, fish, cereals, legumes, com
ding chat she's not going to give up pizza and
oil margarine, sunflower oil, and low-cholesterol chicken wings for the rest of her life.
products like Egg Beaters .
"That's one of your choices," Kohn said. "You
Pasta is good, but be careful of the sauce, he know the risks, and you've got to be willing to acwarned . Fish oils are fine if you use chem instead cept them ."
of saturated fats in your diet. If you supplementyour
When co prescribe d rugs is a very individualdiet with these oils, he emphasized, it's only going ized thing, Kohn said, and strongly recommended
to make you fat.
a rigid diet for the woman. He pointed out that
Shellfish have some cholesterol, but they also if she planned to get pregnant, she should avoid
have a lot of unsaturated fat . So they're fine, but
medication since we don't know the effects on rhe
watch the drawn butter, he added .
developing fetus.
Kohn suggested chat two drinks a day can
Physicians tend to overlook the contributions
elevate rhe levels of HDL, the beneficial cholesterol. co-professionals such as nutritionists can play in
Bue more than two d rinks a day can pose ocher getting somebody to alter his or her diet, Kohn
problems.
remarked in answer to a question .
"I don't know if (it helps reduce the risk of heart
Yeagle also pointed out that there is a whole
disease) because it increases HDL or because it's a family of risk faccors for heart disease, including
socially accepted tranquilizer that makes you feel family history, age, sex, smoking, and exercise.
better;' Kohn said.
Cholesterol levels can't be considered in isolation. •

the moderate to high-risk range can be modified
by diet, said Philip L. Yeagle, Ph.D ., associate professor of biochemistry at UB who has done research
in the basic role of cholesterol in cell membranes .
"Five years ago I wouldn't have believed it," he
added . At the high range, more than strict diet is
needed.
A one per cent decrease in serum cholesterol
leads to a two per cent decrease in risk, Yeagle
added.
"Youcan have a very interesting diet and reduce
your cholesterol," said Robert M . Kohn, M.D.,
clinical professor of medicine at UB and medical
director oflndependent Health. "However, in order
to reduce your cholesterol and keep it down, you
have co stick co the diet . If you go off the diet even
two days a week, you're not going to have a significant reduction in your cholesterol."
Heart-smart refreshments were served during the
break at rhe conference . There was plenty of dip
and lots of celery sticks, bur not a chicken wing
in sight. Instead, participants were treated to fresh
fruits and vegetables with low-fat dips, soda pop,
and tangy "Red Satin Punch" made from apple and
cranberry juice .

LATE WINTER 1988-89

BUFFALOPHYSICIANAND BIOMEDICALSCIENTIST

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�17

Vaccine Lets Virus
Invade-On Purpose
By CONNIE

OSWALD

he soldiers stand ready ar battle stations, prepared to annihilate
rhe enemy. Their duty is to make sure none of the attackers
get into the fortress alive.
That's how conventional vaccines work. Made from a
weakened or nonvirulent form of the virus, the vaccine
stimulates antibodies-the soldiers that fight off infection.
But Edwin D. Kilbourne, M.D., one of the world's leading experts
on influenza, is working on an influenza vaccine that would actually allow
the attacking virus to invade the body.
Kilbourne, a distinguished scientist both in microbiology and preventive medicine, offered a glimpse into his work during the medical school's
Harrington Lecture in October.
One of the founding chairmen of the Mount Sinai School of
Medicine, he's a distinguished professor there and is a member of the
National Academy of Sciences.
Kilbourne's vaccine uses a single, purfied protein of the virus, a technique
that other researchers arc crying as well.
But what's really different about Kilbourne's vaccine has co do with
the antibodies chat are produced . Instead of standing with guns poised
to fend off any invaders, these antibod ies allow the attack ing virus into
the body.
But once the attacking virus gets inside, the
antibodies prevent it from duplicating a great deal.
By keeping the quantity of virus low, disease is
prevented, yet new antibod ies are induced by the
viral attack.
The vaccine would allow the enemy within the
gates, then suppress the enemy's activities, explained Kilbourne .
A study by UB's Pearay L. Ogra, M.D. showed
chat such an infection-permissive approach could
work, Kilbourne said. Ogra is professor of
microbiology and pediatri cs at UB and chief of
the Division of Infectious Diseases at Children's
Hospital. In Ogra's study, Buffalo schoolchi ldren
were given a vaccine similar to the one Kilbourne
is working on.
"Disease was prevented, though not as well
as with a conventiona l vaccine: Kilbourne said.

BUFFALO PHYSICIAN AND BIOMEDICAL SCIENTIST

S1DFKO

"But it showed the approach is feasible. That's the lesson I took
away~
The use of a single purified protein, in this case neuraminidase, is a
technique rhat wasn't available when Ogra's study was done about IO
years ago. It's something char may help overcome some of the drawbacks
of rhe earlier vaccine, Kilbourne noted.
All of Kilbourne's work with the single purfied protein has been done
in mice. The next step is to begin studies in humans. It may be two,
or more realistically, three years before a vaccine is on the market, he
emphasized .
"We've had encouraging preliminary results, but it's not for tomorrow's use in man; he cautioned .
Influenza is a highly significant disease, Kilbourne explained, because
it paves the way for pneumonia which can prove fatal. Even when it's
not fatal, influenza causes fever, aches and pains, and lands people in bed.
"Ir cou ld tic up a whole community; he said. "Ir has a high attack
rate-it can be devastating econom ically.•
The influenza virus produces widespread pandemics of disease in
cycles, every 10 to 30 years. Episodes occur when the antigens change
so much that they confront the whole global population as new viruses.
'So we all become children again in front of
these new viruses,• he said. "We have essentially
no past experience with the antigens ~
One advantage to Kilbournc's vaccine is chat
since the protein used changes less frequently, we
may be able to go for a longer period without
having ro change rhe vaccine.
Kilbourne is hopeful that his approach will provide a better vaccine for young children.
With the present vaccine, child ren under two
years old have about a 25 per cent change of
developing untoward reactions; that is, developing flu symproms from the shoe. If you give them
only a single purified protein, there's less chance
of having a reaction.
"That's a long way from being proved, but we
think that giving one protein is better than giving seven-which is what you have with an intact virus; he said.
•

LATE WINTER 1988-89

�18

Students on ,
These three found f
their love of mus

By MARK M,

hey close themselves inside a foampadded room on a regular basis co
escape the pressures of their hectic schedu les.
No, they're not asylum inmates, bur
some may call them neurotic when it
comes co thei r passion for music. David
Blaustein, Tony Capocelli, and Rohic
"Rob" Bakshi are medical students at UB
and all have pursued their musical interests as disc jockeys on the FM airwaves.
Bakshi, a third-year student, is working
at KYUU-FM in San Francisco. He's caking a leave of absence from UB in order
co participate in neural research at the

LATE WINTER 1988-89

University of California at San Francisco.
Capocelli and Blaustein, both fourthyear med students, currently co-host
ThursdayNight Jazz on UB's radio station, WBFO, 88.8 FM.
Although their styles and musical formats at the stations differ, all of the aspiring M.D.s agree that the air time provides
them much-needed relief from the
tedium and discipline of their rigorous
med school studies.

Capocelliand Blaustein
Tony Capocelli and David Blaustein,
both self-professed "jazz junkies," have

been voicing their musical addiction
across the airwaves at WBFO for the past
thr ee and a half years.
"I love jazz and I love neural regeneration research," the 24-year-old Capocelli
professed . "If I had to choose an ideal
goal right now, it would be to head a
groundbreaking team of neural regeneration researchers and have a jazz band on
the side.
"Even if I never end up running a
research lab, I know I'll always be playing jazz."
Capocelli and his partner in jazz,
Blaustein, met three and a half years ago
through their mutual love for jazz.
"I had just begun med schoo l and was
blowing off a little frustration by jam ming on my alto (saxophone)," explained
Blaustein. "I was in the student lounge
at about 10 o'clock at night, so the place
was pretty empty . Tony, who I didn't
know at the time, was corning back from
the library and heard me playing . So he
brought his acoustic guitar down from
his room and started jamming with me.
We had a really good session ."
Shortly after that, Blaustein and
Capoce lli each began their l-to-6-a.m.
"graveyard shifts" on WBFO-Blaustein
on Satu rdays and Capocelli on Sundays .
Although the positions were volunteer,

BUFFALOPHYSICIAN AND BIOMEDICALSCIENTIST

l
J

�19

the Airwaves
P way to harmonize

1sic and medicine

MARABELLA

l
J

the early morning shifts gave the young
jazz enthusiasts an opportunity to
develop their formats, styles, and selections . The collection of jazz albums in
the extensive WBFO library tops 20,000
records, so it took them both some time
to distinguish their own repertoire of
music for their shows.
"They (management) don't give us any
specific record lists. As long as we stay
within the spectrum of jazz-which is
pretty broad-we can pretty much play
anyone we want to," said Capocelli.
During the year and a half that both
endured the graveyard shift, Blaustein
and Capoce lli started their own
jazz/blues band called Code Bluenamed for their mutual interest in both
music and medicine. Code Blue is an "allclear" signal given in one hospital after
a Code Red, which is the emergency or
cardiac arrest signal. It also represents.the
band's own brand of cool blues music
which alleviates the "Code Red" pressures
of med school.
The six members of Code Blue include
Capocelli on electric guitar; Blaustein on
the alto saxophone; classmates Dave
Vogel on electric violin, Esther Ponce on
synthesizer, and Tom Grimaldi on bass,
and Tom's younger brother Chris on the
drums . Whi le the two-year-old band has

BUFFALOPHYSIC IAN AND BIOMEDICAL SCIENTIST

made no local appearances yet, Capocelli
and Blaustein are hoping to play
sometime on open jazz night at some of
the Buffalo jazz clubs.
Capocelli has been playing the guitar
and working as a disc jockey since his
days as a junior at Windsor Plainsboro
High School in Princeton Junction, New
Jersey. The high school station had a
rock format, so Capocelli didn't develop
an interest in jazz until he worked two
years at WRUR-a jazz station at the
University of Rochester . After completing his undergraduate degree in
neurobiology there, Capocelli came to

UB to specialize in neurosurgery as well
as to pursue his interest in neuralregeneration research.
Since WBFO is Blaustein's first experience in radio, it took rhe ZS-year-old
native Long Islander a little while before
he felt comfortab le behind
the
microphone .
"It (the graveyard shift) was a learning
experience,"
Blaustein
admits.
"Sometimes I thought that I was the only one listening. On the nights that no
one called during my show, it was
sometimes cough to stay awake even after
drinking a six-pack of caffeine-saturated

LATE WINTER 1988-89

�20

Mountain Dew. But after a while both
of us established a fairly faithfu l latenight following. We would get the same
peop le calling the stat ion at the same
time week after week.n
Although it was time-consuming, the
station helped him tremendously in coping with med schoo l.
"The first couple of years of med school
were the hardest for me because of the
constant studying and lab work . I don't
think that I was exactly ready for the
work because after I graduated from
Emory University (in Atlanta), I traveled around the Un ited States for a year
with my buddy . We were proverb ial 'freespirits' -picking up odd jobs here and
there as we needed money. So when I
started med school, 1 wasn't used to the
schedule or the pressure '.'
laustein's primary interests in the
field of medicine include rehabil itation medic ine and functiona l orthopaedics . Because he majored in
psychology and minored in English as an
unde rgraduate, he developed a strong interest in the humanities .
"I'm more concerned with the human
aspect of medicine-like how a patient
is going to function in society after a
traumatic operation. My job will be to
help patients after neurosurgeons, like
Tony, get through cutting them up," he
quipped .
While Blaustein and Capocelli may
one day professionally comp lement each
other, they are current ly combining their
talents on their own jazz show on Thursday nights from 9 p.m. to I a.m. and
have done so for the past two years. They
have also added a jazz/ fusion hour from
midn ight to 1 a.m. Tuning into WBFO
on Thursday evenings, one might hear
Pac Metheny, Jon Scofield, Chic Corea,
or The Yellow Jackets.
"Even though some of the old-time

LATE WINTER 1988-89

'jazz-purist' listeners take exception to the
newer jazz/fusion, overall our listeners
have exceptionally increased since ou r
days on the graveyard:' Capocelli
estimated .
Blaustein and Capocelli are currently
the on ly student disc jockeys on the air
at WBFO.

"Sometimes I thought
I was the only one
listening. But after
a while both of us
established a fairly
faithful late~night
following. We would
get the same people
calling week after
week.''
Bakshi
While Rohit "Rob" Bakshi began both
his medical career and radio career in
Western New York, his recent endeavors
have taken him across the country to the
West Coast . After completing his second
year of med school at UB in May, he
took a one-year leave of absence in order
co pursue neu ral research with Alan
Faden, M .D., at the University of

California at San Francisco. However,
Bakshi has also cont inued performing as
a DJ at KYUU-FM, a "top-40" station in
San Francisco .
Although Bakshi is no stranger to
top-40 commercial radio, he was forced
to start from the bottom on the
"graveyardshift" at the west coast station .
Nevertheless, the Bay Area currently has
the fourth largest popu lation area for
radio in the country, so Bakshi's show is
listened to by thousands of people even
at the wee hours of the morning .
Bakshi developed his interest in radio
when he was a senior at Cornell University. There he entered a disc jockey competition for new ta lent for WVBR, the
Cornell -owned-and-operated
top-40
commercial radio station. Bakshi entered
the competition with a field of 75 ocher
hopefuls.
"1 d idn't really think that I had a
chance because I had never worked in
radio before. But I worked pretty hard
on my demo-tapes whenever I cou ld'.'
"Demo-tapes" are demonstration tapes
used in the music industry to screen prospective DJs for a job.
Bakshi was one of the first of three
chosen for the air. Shortly after, he acquired his FCC / FM license and began
his nine-month stint at WVBR.
After he received his bachelor's degree
in biology, Bakshi started medical school
at UB and made his local radio debut on
the now-defunct top-40 station, WNYSFM 104. He worked the weekend
"graveyard shift" for four months until
the station was sold {it's now Classic Hits
104.1).
Soon after, Bakshi appeared briefly
again; this time playing top-40 on the
weekend graveyards on the popular
WPHD-FM 103.3.
Then in the summer of 1987 Bakshi
was hired at WKSE (KISS 98.5 FM) for
its radio prime-time weekend daytime

BUFFALOPHYSICIANAND BIOMEDICALSCIENTIST

�Medical School

21

Rohit "Rob" Bakshi

shows.
"It was a big break to get the numberone sloe on the number-one local top-40
station;' Bakshi recalled. "l guess they
must have really liked my demo-tapes:'
During his one-year seine at KISS 98.5,
the radio station became Buffalds highest
raced top-40 radio station (for 18- to
34-year-old listenership). Moreover, during the 1987 winter rating period,
Bakshi's Saturday show from 3 to 8 p.m.
was rated number one in Western New
York.
Bakshi, alias "Rob Miller" on the air,
had to follow strict formatting, but still

BUFFALOPHYSICIANANO BIOMEDICALSCIENTIST

introduced several creative features on
his show that made it distinct in Western
New York. He created call-in comedy
spots for such characters as "Pee Wee
Herman" (played by Greg Sambuchi) and
"The Jammin' Grandma" (played by
Bakshi's girlfriend Lorraine Baeum ler).
One phone call in particular brings
back pleasant memories for Bakshi .
"On Mother's Day I called my mother
and put her on the air live. le was pretty
funny be,cause she didn't realize that she
was on clhe air and said some pretty embar rassin1g things ."
As hiis mother, Deebika Bakshi

remembers, Rohic wasn't even going to
apply for the job because he was sure he
wouldn't get it . She encouraged him to
app ly and "the number-one DJ had to
thank his mother on the air."
Rohit's parents have been a prime influence in his life. The 23-year-old was
raised in the Buffalo area where his
father, Suraj Bakshi, M.D., a specialist in
nuclear medicine, works at Roswell Park
Memorial Institute .
Although Bakshi spends weekends
working as a professional top-40 disc
jockey, his medical studies have not suffered. This past summer he secured
fellowship grants from the prestigious
Alpha Omega Alpha Medical Honor
Society and from the Ame rican Heart
Association in support of his work with
neuro logist A lan Faden, founder and
directo r of the Center for Neural Injury
at the University of California at San
Francisco . Bakshi is one of the few pregrad investigators working on Faden's
research team .
More specifically, Bakshi's research encompasses central nervous system injury
and neural-regeneration,
focusing
primarily upon the endogenous excitotoxins, opioids, and their receptors.
Faden's research has been instrumental
in the development of naloxone, which
has recently been approved by the FDA
for testing on acute spinal cord-injured
patients.
"I really love working as a DJ, but my
main objective is to become a doctor. I
don't think I will continue working at a
radio station when I return to Buffalo in
September because my third and fourth
years of medical school are critica l years
in my medica l education . But after I'm
through with my medical training and
have established myself in academ ic
medicine, I would really like to gee involved with radio again," Bakshi emphasized.
•
LATEWINTER 1988-89

�\

22

Handpicked
Ne w student s are talent ed and diver se

By CONNIE OSWALD STOFKO
espire the gloom and doom
predictions about the shrinking
nation-wide pool of applicants to
medical schools, UB had no prob lem
finding talented people to fill its 1988-89
first-year class.
In fact, it sent out only 301 offers of
admission to fill its 135 spaces, noted
Thomas J.Guttuso, M.D., assistant dean
and director of medical student admissions for UB's School of Medicine and
Biomedical Sciences.
This is the lowest number of offers UB
has sent out since 1974, and UB has the
lowest turnover rate of the 12 medical
schools in New York State, Guttuso added. While UB accepted only 2.2 students
for every one who actually enrolled,
some fine medica l schools have had to
accept five students to enroll one, he
said.
"Our school is more popular; Gutruso
said . "Our reputation is improving and
there's less turnover ."
He explained that medical schools
across the country send out acceptance
letters in different months. Students may
accept at one school, then withdraw that
acceptance when they hear from their
first-choice institution .
"Obviously, we're becoming number
one for more people if they stay with us,"
he noted.
According to John Naughton, vice
president for clinical affairs and dean of
the School of Medicine and Biomedical
Sciences at UB, this popularity can be

LATEWINTER1988-89

attributed to the school's improved
facilities, stronger faculty, the diversity
of the program, and economics-the low
tuition and low cost of living in Buffalo.
The warm atmosphere of the school is
another factor, said Guttuso. He noted
that many applicants are offered free
overnight lodging with students when
they come to town to interview. Students
eat lunch with the applicants, and performances by the Dermarones, the student singing group, break the ice.
"Faculty are very warm and supportive
of students, and students are that way
with applicants; Guttuso said. "It's the
general atmosphere in the school."
"It's an environment rhar stresses
achievement and excellence, bur not a
frenzied environment of competition,"
added Naughton.
Students play a strong role in the life
of che school. There's even a new group
chat organizes parents into a support
group for the school, he noted.
"The number of applications is down,
but the quality is nor down-not here,"
said Guttuso. "In spite of all the negative
news about medicine, there are still plenty of people applying" to UB's medica l
school.
Negative publicity about medicine has
eroded the profession's patina of glamor.
What was once seen as a lucrative and
prestigious profession is now viewed as
one filled with long hours and huge
malpractice insurance payments . People
seriously weigh their decision to become

a physician, Guttuso noted, and those
who finally do choose medicine are
usually very dedicated .
"I th ink we'll have excellent physicians
from these classes we have now; he said .
The numbers bear him out. The class's
average underg raduate GPA (grade point
average) is 3.43. The mean MCAT is
55.92, above the national average of 54.
Three of the new students have Ph.D.s
and 15 have master's degrees.
"In genera l, we've been getting very
good classes;• said Naughton . "T he feeling is that the current classes are really
outstanding ."
The students come from a wide range
of academic and social backgrounds .
About 80 per cent majored in the
sciences, with about 46 per cent majoring in biology, 10 per cent in chemistry,
and 7 per cent in biochemistry.
There are a total of 27 majors outside
the sciences. About 13 per cent of
students majored in the humanities and
social sciences and 5 per cent majored
in health-related fields.
Falling into none of these categories are
one student who majored in German
literature, psychology, and biological
sciences; another who majored in
fashion design, and a third who majored
in life sciences.
The adm issions committee tr ies very
hard ro make sure no group is
discriminated against, noted Naughton.
"This is a very representative class,
made up of d iverse people of diverse

BUFFALO PHYSIC IAN AND BIOMEDICAL SCIENTIST

�23

backgrounds;' he said .
"The proof of rhe puddin g is in the
class,• Gurruso added .
The class contains a record-setting proportion of females-48 per cent. There
are 10 black students, four Puerto Ricans,
and one Chicano.
The oldest member of rhe class is 40
years old, and 25 students are 26 or older.
There is one handicapped student .
The largest number of students-70comes from the 8th Judicial District (the
area surround ing Buffalo). Another 37
come from downstate, 17 from the extended Western New York Area, 6 from
upstate, and 5 from out of stare .
Because UB is a State school, it must
favor applicants from New York State,
and some preference is given to students
from Western New York. Bur in order to
show that rhe school is responsive ro its
alumni, children of out-of-state alumni
are now cons idered as local residents.

BUFFALOPHYSICIANANO BIOMEDICALSCIENTIST

They, of course, must have compet itive
credentials.
"The number of children of alumni
from our of state who matriculate is low;
Naughton said, "bur we want them to
know we welcome their applications ." •

Focusedon a goal
usic has always been special to
D,eborah Shuste r of New York
C ity. She received her bache lor's and
master's degrees in music, then played
viola professionally for five years.
Yet she always felt a pull from the field
of medidne.
"My dad's a doctor," Shuster explained .
"I've always loved science and I've always
been fascinated by medicine .
"As a child, I was encouraged to play
music- I got a chance my parents didn't
have. So I pursued music. It seemed the
thing co, do at the rime."

Shuster, now 29, performed with the
Spokane Symphony
Orchestra
in
Washington, played with professional orchestras in Italy and South America, and
free-lanced in New York City with her
own quartet as well as with small orchestras, ballet companies, and opera
companies.
"But it wasn't intellectually stimulating
eno ugh;' she said . "I needed to use the
other part of my brain."
Shuste r attended a special program at
Columb ia University for two years to
pick up the science courses she needed,
free-lancing on viola in her spare time.
When it came time to choose a medical
schoo l, she chose UB for several reasons,
including the affordable price and its
location . Her husband, a guitarist,
teaches in Syracuse, so she wanted to stay
upstate .
Being a cad older than most of the
other students is an advantage as she emLATE WINTER 1988-89

�;\, J

l

I'

I

24

barks on her medical career, Shuster
says.
"I've seen a loc, dealc with people a lot,
and that'll make my job easier; she
noted . "I'm more focused and I know
what I wane."
•

During his Early Assurance interview ,
he noted chat some people feel pressure
co become a physician because they have
a relative who's a physician. But Adams
told the interviewer, "My father's not a
doctor . My mother's not a doctor . The
reason I'm here is because I wane co be
here ."
His inte rviewer cold Adams that, with
his record, he could probab ly go to any
medica l school he wanted . But Adams
decided o n UB beca use it's inexpensive
and he can get a good education here .
He noted that since the facilities have
just been refurbished, he's among the
first to use the new labs. And he likes
the staff.
"It's a grind, bur I really enjoy medica l
schoo l; he said . "It's like one big family.
A lot of peop le have different interests,
but we're all in the same boat, trying to
become doctors."
•

Creative and dedicated

fo.ld

Servingothers
odd Adams, 22, of Grand Island
chose medicine as a career because
"I couldn't picture myself doing anything
else. I couldn't just sit behind a desk. I
wane co work with peop le and help people:'
Adams entered
medical school
through the Early Assurance Program,
which allows qualified students to apply
early. A biochemistry major at UB, he
had a 4.0 average and had taken part in
research . He also volunteered in the
emergency room at Millard Fillmore
Suburban
Hospital,
belonged
to
academic organizations, and enjoyed skiing, golfing, and playing basketba ll.

LATE WINTER 1988-89

felt a real need to help peop le, as
cliched as that sounds," said Hisla
Bates, a first-year medical student at UB.
A successful fashion designer, she
abandoned that lucrative career to pursue her childhood dream of becoming a
doctor.
Born in the West Indies, Bates lived in
Guyana unti l she was six, then moved
with her family co the New York City
area .
In junior high school and high school,
her arc teachers cold her she was very
talented .
"I got so much enco u ragement in arc,
I decided to cry ic; she said. "It seemed
a very exciting career, I was using my
talent, and I felc confident. In science,
I didn't get that kind of encouragement,
though I was a very good student:'
Bates attended the Parson School of
Design in Manhattan , majoring in
fashion design . After graduation, she

worked her way up co become head
designer for Herman Geist and did a
licensee line for Stanley Blacker.
"I traveled extensively thro ughout
Europe and th e Orient; ' Bates said . "I
started to make lots of money, but it still
wasn't satisfying."
After three years as a fashion designer,
she spent four years as an undergraduate
at Hunter College in the City University of New York to pick up her required
science courses . She also d id research in
the Marine Biological Laboratory in
Woods Ho le and at Rockefe lle r
University .
"I'm glad I did it chis way; said Bates,
29. She's seen much of the world and has
developed the confidence chat comes
with success.
Ac che same time, it was hard to give
up a $40,000 a year job where she
managed several assistants . But it shows
one thing .
"I really wane co do this," she said . •

f·hsla Bates

BUFFALO PHYSICIAN AND BIOMEDICAL SCIENTIST

�\[

",l

( I

25

GROUPSTRENGTHENS
FAMILYTIESTO SCHOOL
he notion is very simple;' said
Peter Ostrow, M.D., Ph.D.,
associate dean for curricular and
academic affairs. "Even though your son
or daughter has become an adult and
graduated from college, their need for
su ppor t from their parents doesn't stop .
It may even be greater because medical
school is such a stressfu l time."
Ostrow, along with a group of inspired
parents, spearheaded the establishment
of the UB Medical Student Parents
Council chis past fall. The organization
was form ed in o rder to strengthen ties
between the medical school and parents .
"(The council) is simi lar to the PTA in
grammar school, only it's on a higher
level;' explained Ost row. "Most families
want to be more involved with what's going on in their son's, daughter's, or
spouse's medical education above and
beyond Family Day, which takes place
on ly once a year."
The deve lopment of the council was
spurred by the huge success of Family
Day, an event initiated in 1981by John
Naug ht on, dean of the Schoo l of
Medicine and Biomedical Sciences. The
day allows families to interact with the
medical school's faculty and other
students, and stim ulates interest in the
school and its activities. Families of
freshmen
and sophomores
v1s1t
classrooms and meet facu lty who can
answe r quest ions about courses and
teachin g methods, while families of
juni ors and seniors visit US -affiliated
hospitals where those students conduct
practical rotations.
Naughton introduced the idea of a
parents cou ncil as early as 1981,but it
wasn't until 1986,when attendance at
Family Day surpassed 500, chat the

BUFFALO PHYSICIAN AND BIOMEDICAL SCIENTIST

medical school decided the time was ripe
to develop such an organization . When
Ostrow presented the idea last summer
to parents of UB medica l students, he
met wirh overwhelming ly positive
response.
Gail Pitterman, one of the founding
parents and a member of the council,
spoke about the new organization at the
opening presentation for first- and
second-year students ar the most recent
Family Day.
"The primary goal of the Medical Student Parents Council is to give moral and
financia l support to students and the ir
schoo l;' noted Pitterman.
Pitterman said the council is looking
for volunteers in various cities co ace as
hose families for UB students who need
a place co stay when interviewing for
residency programs. Local hose families
are also needed to accommodate
students interviewing for entrance into
the UB medical school and to provide
hospitality during holidays for chose
unable to return home.
The council is also inviting parents to
work with student organizations and the
UB Foundatio n to plan social, educational , or fund-raising events, and to gee
involved with publicity for the school.

Cu rrently, the council is helping to raise
funds co support the medical school's
Computer-Assisted Int eractive Video
Teaching Aids.
Since the counci l's inception, membership has grown from 14 parents to about
50, most from New York State . Some
parents who find it d ifficult to attend
meetings at UB are consider ing organizing a New York City chapter as well.
"We encourage parents and any othe r
family members to get involved, make
suggestions, or offer their services if
they're interested;' Ostrow remarked .
"There was a very similar program at the
University of Houston where I previously
taught that proved to be very successful
and popula r with the school and the
families of the students .
"What's unique about a Medica l Student Parents Council is that it provides
people with more info rmed support and
activity that isn't always after the
pocketbook .
"We wane our students' families co
know that they haven't lost a ch ild but
have gained a med school;' Ostrow said .
Th ose who are interested in the council can call (716) 831-2802for more infor•
macion.
-By Mark Marabella

LATE WINTER !988-89

�26

~

The Other Classroom
Buffala hospitals maintain a key role in medical education

By JOHN NAUGHTON,
!though numbered among the
oldest of America's medical
schools, UB is one of the few
which has maintained the status of a
"community-based" medical school for
such a long time. Medical historians note
that of the northeastern medical schools
that survived the 1910 Flexner Report,

LATEWINTER 1988-89

M .D.

two, namely UB and Albany Medical
College, chose to distinguish themselves
primarily as centers of clinical training
in which our network of teaching
hospitals was and is a key element .
The merger of the private UB with the
public SUNY system did not treat the
medical schoo l kindly during the early

years of trans ition . It threatened the
bonds between the old UB and its
already existent faculty and hospital
system . The university medical center
that was proposed for the Main Street
Campus or the future Amherst Campus
probably never had any real chance for
success.

BUFFALO PHYSICIAN AND BIOMEDICAL SCIENTIST

�27

We are still, and will continue to be for
the foreseeable future, a communitybased medical school working with a
group of affiliated ho spitals . The major
differences between now and 1962 are
that we have forged through the partnership with the SUNY system a much
larger, stronger, and more secu re funding
base which has enabled the University
and its hospital community co raise their
sights and to become compet itive with
major medical centers throughout the
Stace and the nation .
The cha llenge that the hospitals and
medica l schoo l share is ro develop the interrelationships necessary to use the investment of the citizens of New York
Scace and to make it benefit each of us
as individuals, institutions, and communities . I chink we are on char course,
and, hopefully, when chis century closes,
each of us can look back on the efforts
put forth with a sense of satisfaction and
accomplishment.
The hospitals' principal co ncern in
medical education relates co the role of
residents in the hospital system and the
future of loca l graduate
medical
education .
There are three things we should keep
in mind: First, reform of graduate
medica l education is upon us. Second,
the public policy priorities for graduate
medical education at the federal and
Scace level are ar variance with much of
what occurs in the nation's 127 medical
schools . Third, funding mechanisms for
support of graduate medica l education
will change .
Given the above assumptions, we
shouldn't dwell so lely on the quality of
the graduate medical education programs
in Buffalo. We know char the q ualit y is
good and it will continue to improve.
In stead, we should dwell on any incongruities char exist between institutiona l and recommended pub lic policy,

BUFFAW PHYSICIAN AND BIOMEDICAL SCIENTIST

"We are still, and will
continue to be for the
foreseeablefuture, a
community~based
medical school
working with a group
of affiliated hospitals."

and how these issues might be addressed
and resolved.
simplified statement of contemporary public policy is char we shou ld
prepare more generalists, fewer specialists,
and more physicians from minority and
underrepresented populations.
In reviewing the Buffalo scene, it is apparent chat we are not much different
than the other medical schools in the
United Stares . It appears that almost half
of ou r residents arc in so-called prima ry
care programs, i.e., internal medicine,
pediatrics, and family medicine . Bue of
the 120 residency positions funded for internal medicine and pediatrics, the
number used co train genera lises is about
the same as che number assigned co
fellowships. Since fellows usually come
from an existing residency base, we aren't
in accord with existing Scace guidelines
or developing federal guide lines.
To deal with chis situation, it is clear

that the faculty and the governance
structure of the Graduate MedicalDental Education Consortium will have
co develop strategies for change . Th ese
strategies might include:
• A more formal emphasis on the
value of being a generalise and a proper
reward system for primary-care faculty .
• Transfer of funding for fellows from
the reimbursement system co ocher
resources.
• Increased emphasis on recrumng
fellows whose commitment is broader
than char of achieving specialized skills
for che practice of medicine .
• Transfer or reallocation of a large portion of a resident's education from the
highly technologically oriented tertiary
care center to ambulatory care and community activ ity.
You can see why the school has spent
a certain amount of its energy over the
past few years in reordering its community and hospita l relationships to ensure
a new and needed variety of educational
opportunities . For in stance, fami ly
medicine has been very successf ul in incorporating a suburban and rural network designed to complement its urban
base located at the Deaconess Center.
Pediatrics complements its tertiary base
with o utr each activities ac the Erie
County Medical Center and Buffalo
Mercy Hospital.
Medical students and residents in nonsurgical
and
non-hospital-based
specialties will need educational opportunities in environments othe r than
hospitals, and both full-time and voluntary faculty will be needed co facilitate
and implement the changes .
Two oche r areas of concern are the
distribution of future physicians and the
extension of ou r affirmati ve action program to resident recruitment
and
training .
The former is being addressed by

LATE WINTER JQSS-89

�\I cl t

28

diversification among the primary care
departments, especially in areas such as
family medicine and geriatrics. The
school now has educationa l relationships
in these two areas tied directly to the major reaching hospital system . The combination of these organizations has permitted the development of a balanced
program designed to ensure opportunities in urban, suburban, small community, and rural environments .
As part of the LCME self-study (see
Early Winter 1988 edition of Buffalo
Physicianand Biomedical Scientist), the
clinical chairmen reviewed their performances in recruiting residents from
minority
and
underrepresented
backgrounds. Ir was evident chat the
medical schoo l's commitment was not
adequately incorporated into its graduate
medical education mission. The chairs
affirmed a commitment to give a priority to chis important public policy issue.
They will have to consciously prevent
the current matching system from interfering with this priority .
le is premature to address the issue of
funding graduate medical education, except to state chat New York Stace's new
Council on Graduate Medical Education
has proposed that all graduate medical
education funds provided through the
reimbursement funds be placed into a
centralized governance under control of
consortia.
There is a need to deve lop new training programs as well as to modify the
manner in which some programs are
operated. The Graduate Medical-Dental
Education Consortium of Buffalo has
recommended the development of programs in emergency medicine, radiation
oncology, and plastic surgery over the
next three to five years. Soon we will
cons ider developing another program in
preventive medicine.
It is obv ious that even without the

LATEWINTER1988-89

future constraints imposed by the Bell
Commission, major changes in the conduct of graduate medical education,
especially in the primary care specialries,
will be forthcoming. More emphasis will
be directed toward educational prepararion, less coward service, and more diversity of educational experiences will be required.
•

ADSMAYSWAY
VIEWS
OF BIRTHCONTROL
elevision and radio commercials advocating birth control may help reduce
the high race of pregnancies and abortions in New York State, according co a UB
study.
The study by the Health Services Research
Program of the UB School of Medicine and
Biomedical Sciences found that after exposure
to a limited media campaign, women were
more aware of birth control methods and the
risk of pregnancy without birth control, and
less likely to believe chat birth contro l spoils
the spontaneity of sex and chat it gives men
a false impression of the woman's availability.
The media campaign, which ran in Buffalo
and New York City in the summer and fall
of 1987, used paid commercials, not public
service announcements, said Harry A. Sultz,
head of the Health Services Research Program
and professor of social and preventive
medicine. Researchers also interviewed
women in a contro l city, Syracuse.
The "media messages" were developed by
a New York City advertising agency as part
of a five-year plan by a coalition of family
planning agencies and clin ics to reduce the
high rates of unintended pregnancy and abortion in New York State, Sultz said.
The New York State Family Planning
Media Consortium has 23 members from
across the state. The Buffalo-area members
arc UB, Planned Parenthood of Buffalo and
Erie County, Deaconess Center, and Planned
Parenthood of Niagara County.
The four messages in the campaign's

(Ml 5IC THROIJGHOL 11 SONG·
Lon.[!er than there't c been fishes m the
ocean,

l11gher than uny bird

0111;er

t'll

r flen,

thun

BUFFAID PHYSICIANAND BIOMEDICALSCIENTIST

�29

30-scconcl radio and television spots,
underscored with music by singer Dan
rogclberg, were:
• Birth control: from saving no co takmg
rhc Pill, you're coo smart not co use it.
• Four out of five young women who don't
u,e birth control get pregnant before chev
want co.
• Boch young men and young women in
a caring relationship arc concerned about
having children at che right tame. (Young, obviously carmg, couples arc featured in the
celcv1s1onspots).
• Call 0ocal telephone number) or look
under "Binh Control" in the yellow pages.
"The intcrt.'Stmg thing is, nowhere, in either
Buffalo or New York, wa, there a negative
reaction," Sulc: noted. "They didn't get any
letters, they didn't get any complamcs. In face,
the ads in New York City had the New York
Cn~ Health Department's Health Lmc
telephone number on them, and there was
an immediate Jump in the number of calls to
the Health Linc asking for information."
The spot wa, aired during prime time on
two network-affiliated television ,rations m
Buffalo and on rwo Spanish-language television scackms in New York, Sulcz said .
Howt.·ver,the maior telC\'l'IOn,rations in Nt.'\\
York said che ,pot was coo controvcrnal and
wouldn't nJn the ad. The same mformauon
then was placed on 12-foot placards on 500
New York City buses, on carcards on all sub\\ay Imes in the city, and on six radio srat1on,.
Once the evaluation of the media campaign
wa, completed, the family plannmg consortium placed the television ad m prime t1me
m all nine maJor media markets around the
Mate, Sult: ,ay,. WWOR-TV, one of New
York City's independent television stattons,
then approved the ad and aired tt m prime
time, he n,oced.
The scud, offer, proof that birth control
is ,1 way of life for the maJ0rtt\ of young
women, Sultz sm&lt;l.Overall, two-rh1rds of sex•
ually active women reported they always uSt.--d
birth control. A little more than 16 per cent
ne\er used birth control, while 16 per cent
said they sometimes used contraception.
These fig,urcshelp researchers pinpoint rhe
population at risk for unintended prcgnan-

Bt..FFALO
PHYSICIANA:-.;OIIIOMWICALSCIENTIST

cy and abortions: those women who never
use birch contro l or arc haphazard about its
U!'C, about a third of the sample, Sult: says.•
- B) S11e\\½,etcher

CALIFORNIA
DEAN
IN APRILWill DISCUSS
CAREEDEVEL
R
OPMENT
Lyn Behrens, M.D ., dean of the
S(hool of Medicine at Loma Linda
e University, will give presentations
on professional development as che first Harrmgton Visiting Profe,'\Or at UB.
The program will run from April 25-28.
Bchrcm is becoming recognized nationally as an expert on profc,,1onal development.
One of only three female deans o( medical
schools 111 the country, she 1, active in
AAMC, especially m programs on advancing the car~-ersof \\Omen.
Topics for the introductory program include
advancement
in ncn&lt;lemia, policies of
academic institutions,
and professional
growth. There will be a short program on
UB's servKt.'Sfor rt.-,,earchers.
A whole day will focus on research planning, including the characteristics of producttve researchers, the nuh and bolts of research
design, and the Loma Lmda faculty model.
A management workshop will al,o be held
for a small number of people.
The program will include the Annual
Faculty Research Day, whe re faculty will
display posters summarmng their research.
Behrens will be available co addrc&lt;&lt; small
groups of faculty .
The Harrington V1s1tingProfessorship is an
expansion of the spnng Harrington Lecture.
The new format allow, the v1s1tmg scholar
m spend more time at UB developing a topic.
The school will continue co sponsor its fall
Harrmgcon Lecture.
For more information,
call Glenda
Donoghue, APFME director of Continuing
Medical Educat ion and Professional Development, at 831-3714.
•

LATE WINThR 19!18-89

�30

WE BID FAREWELL
TO LOISLEWIS
ired in September 1959 when UB was
still a private institution, Lois Lewis
has worked in the dean's office at the
medical school through four University
presidents, five med school deans, and explosive student riots. She has also watched
the progress of the Amherst Campus from its
meager beginnings as a swampy flood plain.
"I've seen a lot of changes in UB and the
med school during my 28 years working here,"
Lewis recalled, "and even though I'm happy
co be retired, I'm going co miss the University and the med school very much."
In late September, John Naughton, dean
of UB's School of Medicine and Biomedical
Sciences , held a buffet reception in the new
lobby of the med school to honor Lewis, who
had served as his senior staff administrative
director since Naughton joined UB 13½ years
ago. More than 100of Lewis' friends and colleagues came to the reception where
Naughton presented Lewis with a captain's
chair inscribed with the UB seal for her 28
years of contributions and dedication to UB.
"She is missed already and will be difficult
to replace," Naughton remarked. "She cook
pride in everything she did. She paid attention co every detail and always wore a smile.
We all wish her the best in her retirement
because she deserves ic.•
"If Lois Lewis couldn't find something char
was requested, then it wasn't findable," Peter
Ostrow, associate dean of the med school,
said. "She was dedicated and personally involved in the life of the school. She was
always a pleasure co deal with and made me
feel at home when I first came to UB in 1984.•
However, working at UB has nor always
meant good rimes and parties. Lewis
remembers vividly when student riots erupted
on the Main Street Campus in 1969-70 and
police occupied the troubled University at che
request of Martin Meyerson, president of the
University at the rime.
"We were evacuated from our offices several
times because of smoke bombs and the
general threat of violence," Lewis recalled.
"The students were protesting (federa l)

LATEWINTER19SS-69

government contracts with UB. At the time
there was hyperbaric research (the study of
rhe physiological effects of high pressure) going on in Capen (now Farber) which was contracted with rhe Navy. They were protesting
right in front of our building, so we could see
them demonstrating from our windows. It was
difficult to enter or leave the building without
being harassed by all the people from rhe 'sicins: Ac one point our staff was locked into
the office for our own protection. It was a
scary time."
evercheless, che campus soon became
less explosive as talk of a new campus
in Amherst spurred the imagination s and expectations of everyone involved with UB.
"Originally the med school was planning
ro be relocated into Hochstetter Hall on rhe
Amherst Campus, but they decided lacer that

Main Street was the best location because of
its close proximity to the hospitals in Buffalo,"
Lewis recollected.
"It didn't really bother me, though, because
I like the Main Street Campus better anyway.
It seems more endearing and the city location gives it some character . The Amherst
Campus is coo cold and isolating, bur I guess
I'm partial," Lewis commenced .
"When I first came to UB in 1959, the med
school was part of a small private college and
graduated a total of only 60 students. Now
the med school is a State school with one of
the largest budgets for research in the University. The size of the graduating classes have
more than doubled while the faculty has tripled."
Lewis, a 30-year member of the Professional
Secretaries Association, enjoyed the work she
did for the University. Working as the

BUFFALOPHYSI
CIAN AND O!OMEDICALSCIENTIST

�31

manager of the dean's office always kept her
busy, she says.
"There was never a dull moment at the
University. There was always something
happening-a
lot of action," Lewis
remembered. "The dean's office was always a
busy place, especially since Or. Naughton arrived in 1975. He is one doctor who doesn't
play golf on Wednesdays. He doesn't even rake
a lunch break."
Lewis plans to spend her retirement traveling and visiting her friends. Although she will
miss the day-co-day pace of the medical
school, when asked what she would miss most
about the University, she stated simply, "All
of the people."
•
-By Mark Marabella

SCHOOL
EXPANDS
EARLY
ASSURANCE
he UB School of Medicine and
Biomedical Sciences has expanded its
Early Assurance Program to qualified
undergraduates at any college, and now offers Early Assurance in the M.0./Ph.O.
program.
Previously, the program was open only to
undergraduates at UB and Canisius College
who wished to pursue an M.0. here.
Students who are accepted into the Early
Assurance Program know in their junio r year
of college chat there'll be a spot waiting for
them in the medical schoo l, explained
Thomas J.Guttuso, assistant dean and director of admissions for the UB medical school.
The purpose of the program is co attract
highly intelligent students and allow them to
pursue a broader range of classes in their last
two undergraduate years, Guttuso explained.
Students often feel chat they must rake certain science courses that will look good on
medical school applications, leaving little time
to explore the humanities, he said. In addition, many juniors reduce their courseloads
to study for the MCAT, further limiting the
variety of courses they take.
Since they don't have to rake the MCAT
and the pressure of getting admitted to
medical school is off, Early Admission

BUFFALOPHYSICIANANO BIOMEDICALSCIENTIST

students can broaden their backgrounds
beyond science, making chem well-rounded
individuals.
Students need about a 3.5 average in
science and non-science subjects and must
have completed half of the courses required
by the UB Medical School before they can
apply, Gurruso said. They must be residents
of New York Stace.
After they're accepted, students enroll in
a clinical preceptorship to see how medicine
should be practiced. For local students,
preceptorships are arranged at UB. For those
living outside of the Buffalo area, arrangements are made with a UB alumnus.
Students in the M.0./Ph.O. program are expected to have conducted research before applying to the program. After acceptance, they
are encouraged to continue their research at
their own college or at UB.
Other medical schoo ls in New York State
have established early assurance programs
and are considering expanding them.
•

THIERTO SPEAK
AT
SPRINGCLINICAL
DAY
r. Samuel 0. Thier, M.0., president of
the Institute of Medicine, National
Academy of Sciences, will be the
Stockton Kimball lecturer at the annual
Spring Clinical Day and Reunion Weekend.
Thier will speak during the scientific session on Saturday, May 6. The theme for the
session is "Nutrition in the '90 s."
The weekend will begin with an evening
reception for the reunion classes on Friday,
May 5.
For more information, call the medical
alumni office at (716) 831-2778.
•

MERRILEE$
DONATES
ANTIQUEMICROSCOPE
n antique microscope valued at $6,500
was donated to the Health Sciences
Library's History of Medicine Collection by William H. Merr ilees, M.0., C.M.,
associate professor of obstetrics and
gynecology at UB.
A gift from his father, William Merrilees,
Ph.D., upon Merrilees's acceptance into
medical school in 1936, the Powell and
Lcaland No. I microscope was hand-built in
England in 1884. It marked the summ it of
microscope design and manufacture in
England for over 50 years.
This microscope was renowned in its time
for its innovatively designed stage, which
could be rotated 360 degrees, and its steadying stand, which singly required at least 600
man-hours of production. It also introduced
the unique ability to be converted to a
binocular device by simply unscrewing its
monocular eyepiece and replacing it with a
binocular eyepiece.
Merrilees has also donated 21 titles of
medical monographs from the turn of the
century.
•

LATE WINTER 1988-89

�\

VOTERS
GIVEMORE
POWER
TOECMC'S
BOARD
OFMANAGERS

The board now can
deal with issues in a
timely and businesslike
fashion, with less
political influence, says
the chairman.

he board of managers of the Erie County Medica l Center has more power over
the day-to-day operations of the
hospital, thanks to a new law that was effective Jan . I. The legislation allows the board
to deal with issues in a timely and businesslike
fashion .
"We felt it was very critical because in the
eyes of the New York State Health Department, we had the responsibility, but not the
authority co ace; said Kevin I. Sullivan, chairman of ECMC's board of managers.
The law, passed by referendum in
November, "allows us to be more responsive,
reduces delays in acting, and reduces political
influence over the day-to-day actions of the
hospital," he said.
Sullivan noted that the county legislature
retaii:is certain powers. The board of
managers must report to the legislature before
programs or services are curtailed. The county
still bargains with unions, and the county
decides how large a subsidy it will give the
medical center.
In 1988, the county supplied $5.9 million

LATE WINTER 1988-89

K

11

l ~11ll1 m

d,c 1rma11 of E( MC\ board

of mcma

LTS

BUFFALOPHYSICIANAND BIOMEDICALSCIENTIST

�33

of ECMC's $117 million annual budget. For
1989, the county subsidy is $6.9 million .
The county subsidy, along with some Scace
money, goes toward care of the indigent. Mose
of the ocher money in ECMC's budget is
received through fees for service, including
third-party payments, Sullivan said.
The move co governance by a board of
managers was prompted by a fiscal crisis in
the early 1980s. The county's subsidy co che
medical center zoomed up co $24 million in
1984.
In 1985, the hospita l superintendent resigned and the firm of Ernst and Whinney
was hired to provide interim management.
Lacer that year, the board of managers was
created co govern the hospital.
A cask force sec up by the county identified
five long-rerm objectives:
Keep ECMC open.
Reduce operating costs and financial
losses.
Continue co serve the community with
special attention co the indigent.
Operate the facility in a businesslike and
cost-effective manner .
Continue a leadership role in medical
education.
Also, in 1985, che county reduced its subsidy co $7.7 million.
In 1986, the Vitalnet Group, an independent management firm, was retained to
manage the hospital. The goals of its two-year
contract were to improve the hospital's operation, ease its drain on county taxpayers, and
separate it from political influence. The county further reduced ECMC's subsidy to $6.6
million .
In 1987, the medical center repaid co the
county $10 million for loans it received during its fiscal crisis.
Lase year, the Vicalnet Group decided co
let its management contract expire and the
referendum was held. Now the board of directors, through a chief executive officer and
financial officer, is empowered to operate the
hospital on a day-to-day basis.
The law also provides two new board
members, one appointed by the majority of
the legislature and che ocher by the minority. That brings the board to 13 members, all

BUFFALOPHYSICIA
N AND BIOMEDICALSCIENTIST

of whom are voluntary and receive no fee,
Sullivan noted.
•

DEACONESS
STARTS
GERIATRIC
CLINIC
he Deaconess Center of Buffalo
General Hospital has begun a series of
geriatric clinics to help families with
assessing and coordinating care of the elderly.
During the weekly sessions, the clinic staff
primarily provides consultation to caregivers,
though some primary care services will also
be provided, said June Chang, M.D., director of the clinic. Chang is also an assistant
professor of medicine at UB.
The clinic directs families co appropriate
services and helps with concerns that arise
when the patient is under the care of several
specialists or takes mu ltiple medications. •

NURSING
FACILITY
NAMESLEVITT
acqueline Levitt, M.D., was recently ap•
pointed medical director for rhe Sisters
of Charity Hospital Skilled Nursing
Facility. A geriatrician, she is on the faculty
of the Geriatric Division of the Department
of Medicine at UB.
Levitt is also associate director of the Division of Geriatrics/Gerontology at Buffalo
Veterans Administration Medical Center,
medical direccor of the Odd Fellow and
Rebekah Nursing Home in Lockport, and
associate medical director of both the
Amherst Presbyterian Nursing Home and the
Rosa Coplon Nursing Home.
A graduate of the University of Chicago,
Levitt received her medical degree from the
University of Illinois and completed a residency in internal medicine at UB. She is a
diplomace of the American Board of Internal Medicine and the American Academy of
Family Practice.
In addition co professional memberships in

the American College of Physicians,
American Geriatrics Society, Maimonides
Medica l Society and the Network on Aging,
she is on the advisory boards of the
Alzheimer's Disease Association and the
Carer's Association.
•

NEWMEDICAL
STAFF
ELECTED
AT MFH
orman E. Hornung, M.D., EA.CS .,
clinical assistant professor of urology
at UB, has been elected president of
the medical staff at Millard Fillmore
Hospitals.
Hornung is a practicing surgeon in rhe
Department of Urology at the hospitals and
has been a member of the hospitals' medical
staff for the past 20 years. He received the
American Medical Association's Physician's
Recognition Award for the past seven years.
Ocher elected medical staff officers include
Robert Barone, M.D., clinical assistant professor in surgery, the new president-e lect, a
member of MFHs' Department of Genera l
Surgery; Andras Vari, M.D., clinical assistant
professor in medicine, secretary, medical codirector of the Western New York Sleep
Disorder Center, and Thomas Cumbo, M.D.,
clinical assistant professor in medicine,
treasurer, chief of Infectious Diseases with the
hospitals' Department of Internal Medicine. •

CORRECTION
"

lease note chat in the Buffalo Physician
and BiomedicalScientist, Vol. 22, No.
3, page 7, the edifice you identify as
the 'Forbidden City' is in fact 'The Hall of
Prayer for Good Harvest' in Tiancan Park,
commonly known as the Temple of Heaven
Park! This important site is sou ch of the Forbidden City but linked co it ceremonially
since the ancient emperors of China paraded in majestic style from the imperial palace
co the Temple of Heaven at the time of the
winter solstice to invoke the gods!"
- Marshall A. Lichtman, M.D.

LATE WINTER 1938-89

�34

Vic tor Panaro (M'52) • was
elected councilor of the American
College of Radiology
and
member of the Board of Directors
of the New York State
Radiological Society.

Harold K. Palanker (M'40) •
of Albuquerque, N .M., was invited by the chief of surgery of the
University of New Mexico to be
a founding member of the Albuquerque Surgical Society.
John D. White (M'40) • was
honored for over IO years of
meritorious service as a consultant to the Florida Health Professional Services, Inc.

Abraham S. Lenzner (M'41) •
who has a private practice in
psychiatry in Norwich, Vt., was
appointed
a fellow of che
Academy of Psychosomatic
Medicine and is now an attending at Mc. Ascurney Hospital and
Health Center.
Gilbert B. Tybring (M'45) • informs us chat he had coronary
bypass surgery in 1988. Dr. Tybring, who is retired, is editor of
che newsletter of the Wisconsin
Psychiatric Association, Wisconsin Psychiatrist.

Reinhold Ullrich (M'53) • is
president of the 10,000-member
Los Angeles County Medical
Association for a one-year term.
Dr. Ullrich has a private practice
in obstetrics and gynecology in
Torrance, Calif.

Joseph P. Armenia (M'62)
retired from active practice as a
specialist in Internal Medicine
with the Kaiser-Permanente
Medical Care Program in Harbor
City, Calif. During my 33 years
with Kaiser, 1 served as chief of
the Department of Medicine,
medical director of the Harbor
City Medical Center, and for the
last 11years in clinical practice as
a general internist."

Edward Sha nbrom (M'Sl) •
who was among the first to
recognize the potential
of
detergent treatment co inactivate
viruses in blood produces, has
Geo rge H. Mix (M'47) • in- assigned his patents co the New
York Blood Center . Dr. Shanforms us he is retired and living
in Summerland Keys, Fla.; "Life brom, senior consultant in che
Lindsley E Kimball Research Inin che Keys is great."
stitute of the blood center, will
Philip C. Dennen (M'49) • of participate in pilot studies co be
conducted jointly at Alpha
Middlebury, Conn., is che author
of the textbook Dennen's Forceps Therapeutics and the blood
co
improve
so lDeliveries,Third Edirion, published center
venc/decergcnt
technology.
in lace 1988by EA. Davis ComResearch has resulted in a new
pany. The forward co the book
procedure which uses a special
was written
by Kenneth
organic solvent cogecher with
Niswander (M'48).
detergent to inactivate viruses
that can contaminate blood produces. The success of che method
was demonstrated in a clinical
Jay B. Belsky (M'S 1) • writes study of the blood center's antihemophilic factor concentrate.
from San Pedro, Calif., "I have

LATE\\~NTER 1988-89

Milton Alter (M'SS) • of
Philadelphia,
writes,
"In
September 1987,I stepped down
as chairman of neurology at Tem•
ple Univers ity Hospital (after 11
years - 1975-1987)."
William J. Sullivan (M'SS) •
of Los Angeles, Calif., is a
diplomate of the American Board
of Psychiatry and Neurology. He
is certified in psychoanalysis and
is now specializing in forensic
psychiat ry.
Philip A. Brunell (M'57) • is
president of the Society for
Pediatric Infant Disease and
editor-in-chief of PediatricInfant
Disease News. Dr. Brunell is
associate director for academic affairs and chief of pediatric infant
disease at Cedars-Sinai Medical
Center, Los Angeles.

Edwin R. Lamm (M'60) • is
president-elect of th e medical staff
of Lakeland Regional Medical
Center, Lakeland, Fla.
Kenneth Be ll (M'61) • has
been appointed associate medical
director for Kaiser Permanente in
Orange County, Calif. As chief of

staff for the medical center
located in Anaheim, he is responsible for selecting physicians, setting medical policy, planning new
programs, and administering
budgets. Dr. Bell is an associate
clinical professor of obstetr ics and
gynecology at the Unive rsity of
California (Irvine) School of
Medicine.

Joseph P. Armenia (M'62) •
received the 1988Citizen of the
Year Award from the Western
New York Chapter of the
American Diabetes Association
on May 25. Armenia is a clinical
associate professor of medicine at
UB and chief of the Division of
Endocrinology at Mercy Hospital.
During the past 20 years, he has
been instrumental
in the
organization an d development of
the local chapter of the diabetes
group. He served as its president
for many years and is currently
chai rm an of the board.
Jr.
K e nn et h H. Eckhert,
(M'68) • has been appointed
chairman of Sisters Hospital
Department of Surgery. Eckhert
is medica l d irector of che
hospital's Breast Care Center and
is ch ief of surgery at St. Francis
Hospital.

Maxine Hayes (M'73) • of
Bellevue, Wash., has been named
director of the Bureau of ParentChild Health Services wich che
Department of Social and Health
Services. Dr. Hayes is serving an
executive session four-year term
with the John E Kennedy School
of Government's
(H arvard
University) Center for Health
and Human ResourcesPolicy.She
has also been selected as che Har-

BUFFALOPHYSICIANAND BIOMEDICALSCIENTIST

�35

D ouglas Pl eskow (M'8 2) •
writes chat he and his wife Ran•
di Ples kow (M'82 ) completed a

vard School of Medicine's Fae
Golden Kass Lecturer for 1989.
Israel J. Ja co bo wit z (M '73) •
of Brooklyn, N.Y., has been appointed director of the Cardiovascular and Thoracic Division of the Maimonides Medical
Center.

GI fellowship last year. "Randi
and I have a two-year-old
daughter named Sara. Randi is an
assistant professor of pediatrics at
Tufts Medical School and I am an
instructor of medicine at Harvard
Medical School."

Larry R. John so n (Ph .D. '73)
• is project coordinator of rhe
Oregon Health Sciences University Lung Health Study in
Portland. He is partly responsible
for spirometry quality control at
10 study sites and consults on
Chinese and Japanese spiromerry
longitudinal studies.

Steve n

J.

Morri s (M'73) •

received a J.D. degree from
Georgia Stare College of Law in
1988 and is a member of the
Georgia Bar. Dr. Morris has a
private practice
of gastroenterology in Atlanta and is a
clinical associate at Emory
University. He is president of rhe
Georgia Gastroenterologic Society. Dr. Morris is married and has
four children.

Michael Rowland (M'75) • of
Pinehurst,
N .C., is general
surgeon of the Pinehurst Surgical
Clinic and vice president of the
Norrh Carolina chapter of the
American College of Surgeons
and chairman of the Cancer
Committee of Moore Regional
Hospital.

Bess Mill e r (M'77 ) • a medical
epidemiologist, division of tuberculosis control at rhe Centers for
Disease Control, writes, "The job
is great-and if that doesn't keep
me busy, my husband and I have
two little boys: David, 4 years,
and Matthew, 11/2 years-who do
keep us busy!"

Paul A. Gree nb erg (M'84 ) •

Mi chael Row land (M '7 5)

writes, "After doing rwo years of
surgery and three years of
medicine, I'm on my way to do a
medical oncology fellowship at
MD Anderson Tumor Institute in
Houston."

Tumor Institute. He helped found
the Head and Neck Surgical
Society, the James Ewing Society
(now Society of Surgical Oncology) and the Radium Society
and was president of each.

James D . Tyner (M'29) • died
on April 29, 1988in Newark, N.Y.
He was a past president of che
Wayne County Medical Society
and a founding member of the
American Academy of Family
Practice .
Ric hard Taylo r (M'30) • a

others, Leah and H:adass. Ir's
because I became a certified
mohel."

B o n n ie Ri c hard so n (M '85) •
announces that she is scarring a
private
practice
in family
medicine in Hudson Valley, N.Y.
Dr. Richardson's daughter, Emily Fjaellen Thompson was born
in August 198i.

M a rk S. B ore r (M'80) • is staff
child psychiacrisc and director of
the Dover Day Ho:spical for
Troubled Youth, Dover, Del.

David Stein (M'87) • is a resident in medicine
at the
Massachusens Medical Center in
Worcester, Mass .

general practitioner in Blasdell for
51 years, died Oct. 24 following
a long illness. He was 82.
Born and raised in Hamburg,
Taylor served as the town's health
officer from 1935co 1975.He also
served as the physician for the
Blasdell and Frontier Central
schoo ls, for the Blasdell Fire
Company, and for the Eric County Fair and Exposition. He was active in many UB fund drives.
Taylor is survived by his wife,
three sons, 12grandchildren, and
a great-grandchild.

Anth ony S. U ng er (M'8 0) • a

Bruce R. Saran (M'88) • mar-

Charles F. Banas (M'37) • chief

clinical instructor a't George
Washington University Medical
Center, recently published "Total
Ankle Arthopla sty" in Operaci1:e
Orchopaedicsedited by M. Chapman, M.D.

ried Robin I. Kauffman in Occober 1988.Dr. Saran is a resident
at the Medical Center
of
Delaware, Dover, Del.

of scaff at Mercy Hospital from
1966to 1986,died September 13,
1988. He was 75.
Born and raised in Buffalo,
Banas joined Mercy Hospital in
1938 as a family practitioner.
From 1942 to 1946 he served in
the Army Air Force-Air Transport
Command, Medical Corps . In
1952 he instituted the Allergy
Clinic at Mercy Hospital and
served as its director for 30 years.
He also helped co-organize the
General Practice Section and
served as its first president. Banas
served as the first chief of the
Genera l Practice Department
from 1956 until his appointment
as chief of scaff in 1966.

Wes ley S. Bl ank 1(M'80) •
writes, "Nan and 1 ha,d another
baby girl, Rebecca, to join our rwo

Joe l Fiedler (M'81) "' is clinical
assistant professor of pediatrics at
Sc. Christopher's Children's Hospital in Philadelphia, Pa., and an
allergy consultant for rhe North
Jersey Medical Group.

Mark M. Chun g (M '82) •
writes, "I am a practicing pulmonologist in Ora nge County, Calif.,
and a member of the pr'ofessional
staff of UCLA."

BUFFALOPHYSICIANAND BIOMEDICALSCIENTIST

W illi am S. Mac Co mb (M'2 7)
• died at his home in Walnut
Creek, Calif., Sept. JI, 1988. He
is survived by his wife, Janet,
three sons and a daughter. Dr.
MacComb lived in Houston from
1952 to 1974. He developed and
was chief of rhe Head and Neck
Service and was professor of
surgery at the University of Texas,
M.D. Anderson Hospita l and

LATE ll.1r&lt;TIR IQ~

�AlHmm

36

CALLFORNOMINATIONS
our president and Board of Governors
has, over the past several years, received
many requests for Alumni/ae to
establish a Distinguished Medical Alumnu s/a
Award. Therefore, your president and board
arc seeking nominations for this award to be
presented annually beginning this year.
The award will be presented to a graduate
who has distinguished himself/herself nationally or internationally in the eyes of
his/ her peers and has made an outstanding
contribution to medicine, the arts, or
humanity during his/her career.
The selecltion will be made during the summer and the award will be presented in the
fall at a special award dinner.
Please forward the name of your nominee
as soon as possible on the attached card. A
June 30 deadline has been established for the
receipt of all nominations. Your cooperation
is absolutely viral if this is to be a true alumnus /a award.

our way of showing ou r appreciation to the
members for their past suppo rt of the school.
Preparation is under way for the 1989
meeting of the society.
The James Platt White Society is named for
one of the founders of the medical school
who was in private practice in Buffalo from
1835-1875. A founder of the American
Gynecological Society and one of the
founders of several Buffalo hospitals, he made
important contributions to the practice and
teaching of obstetrics.
•

GUTTUSO
GIFT
CREATES
TWOAWARDS
wo new annua l student awards have
been created, thanks to a fund
established by Thomas J. Guttuso
(M'60), director of admissions for the UB
Medical School.
One award will go to a senior medical student who has contributed most significantly
to research in ophthalmology or who has
demonstrated significant concern for patient
care while in ophthalmology service.
The oth er award will go to a resident who
has contributed
most significantly to
ophtha lmology overall.
Guttuso has a private practice in Lockport.
He is a member of the James Platt White
Society (the school's highest gift recognition
group) and the President's Associates (the
University's highest gift recognition group).•

JAMES
PLATT
WHITE
SOCIETY
TOURS
NEWFACILITIES
DURINGANNUALMEETING
he third annual meeting of the James
Platt White Society, a group of major
annual contributors to the medical
school, rook place on Friday, Oct. 21, in the
Lippschutz Room of the school.
In addition to a tour of the new medical
school facilities, the members and their
spouses and guests were treated to an excellent
afternoon program. The topics ranged from
cardiology in Buffalo to bioengineering in
anatomy to biotechnology and the human
side of AIDS. The topics were excellently
presented by facu Icy, not on Iy from the
School of Medicine and Biomedical Sciences,
but from nursing and physiotherapy.
The capstone for the day's meeting was a
cocktail reception and dinner in the Center
for Tomorrow on the Amherst Campus.
All members of the society received an
engraved Jeffersonian pewter cup. The cup is

LATEWINTER 1988-89

DIRECTORIES
SLATED
FORMAY DELIVERY
he UB Schoo l of Medicine and
Biomedical Sciences Directory is coming soon!
This comprehensive new volume is a compilation of the most current data on more
than 4,655 medical school alumni/ae. Now
chat the editing, proofreading, and printing
are almost finished, the distribution of this
impressive edition will scare.
All alumni/ae who reserved a copy shou ld
receive it around May 5. If you have a question on your order or wish to place an order,
contact the cuscomer service department of
Bernard C. Harris Publishing Co., Inc., 3
Barker Ave., White Plains, N.Y. 10601. The
phone number is (914) 428-8921.
•

HERE'S
ONEMORE
hen we ran one photo of each reunion year in our Autumn 1988edition, we thought we had all of the
bases covered. Bue there were two graduating
classes in 1943 and we inadvertently left out
the spring graduates. Here they are, with our
apo logies: Front row: Harold P. Graser, Gertrude S. Swarthout, Kenneth W. Bone, and
William H . Georgi. Back row: Duncan K.
Macleod, Richard S. Fletcher, Richard J.
Buckley, Charles C.B. Richards, Alfred S.
Evans, and Joseph H. Melant.

BUFFAW PHYSICIAN AND BIOMEDICAL SCIENTIST

�,,

�MEDICALHISTORICAL ~1~,
KIMBALLTOwER, SERIALS DEPT,
MAIN ST., CA"1PUS
c-/
BUFFALO NY 14214

ff1Jfrl

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                    <text>Vol. 23, No. I

Spnng 1989

and Biomedical Scientist

~
Procedurecan save lives­
but donor organs are needed

�STAFF
EX[ Cl 'TIVE E[)ffilR
UN vl'RSITY PL RLIC'ATK'NS
Rehcr1 T M irlcr
6t'rFALO ffi'r&lt;;IC IA1\ l'[)ffi)R
C ( l'OIC ()s, 1ld S10110
ART o: {fC'Tl 'R
A, in I Kcgl.r

Dear Alumniand Friends:

0

n Feb. l, President Stc\en B. Sample announced that the
L'nhersity at Buffalo had h,ecn ,m1t&lt;.-dto jom thc_prest1g1?us
Assoc.1at1onof AmL'T!&lt;.an
Gmversmc-s (AAUl. Tlus orgaruzallon, founded in JQOO
, has 5o members, .1 rcprt-s&lt;.:nt,ltlonof tw0
per cent or less of all American umvcr,mes .
Sigmfkant in this v~-ar'sadmissions 11asthe fact char rno p:1bhc
inst1tut1ons, both from the East, rather than one publ1&lt;.and one
private in,titution, each w&lt;:reasked to JOlll. The Uruversity at Buf•
falo 1s rhe first public institution from either ~ew York St.tte or
New England Jdmirred w th&lt;: organi:arion. The other invitee is
Rutgers University. The other member institutions from Ne11 York
StJte &lt;1reColumbia, Cornell, ~ew York University, Syracuse, and
the Umvers1ty of Rochester.
Our acceptance into this important organi:ation signifies the
growth and academK maturity that has resulted in the short period
of 25 years smcc the merger of UB with the SUNY system. Tod av,
Buffalo's l.Jnivcrsity rep resents a comprehensive unit committed
to excellence in research and teaching, and to servicing a broad
public mission.
Special recognition and congratulations are due President Sample, who set this achievement as a major goal from the beginning
of his presidency seven years ago. There is little doubt that all of
us who current'.y associare oursdves with this academic eN&lt;-rprise
and those who J0tn and follow us will benefit enormously in the
years ahead. \X'e owe the fTes1dem ,:md Sl.JNY a great debt of
gratitude. I hope ) ou are as pleased as we are.

ADVISORY BOARD
Dr John :--=au~hton,rli.:,rman
Dr. H .old Brody
?\ts. N1n1.y GI C\.O

Dr. James Knrua,
Dr t harl~ P O ,ncll·
\.tr. G~•&gt;:"',' Zinc:

Dr Antoinette Pctcr-s
Dr. l harlc Pru, •
Dr. l ,1&gt;i., Rob·.,-;on
r&gt;r. rhor RiY.-tnt•11
Dr. S.k•d, Sures
[)r

b1..rron ')in.ge--man

Dr :01erhcn '&gt;1 ulJinc
Dr ?\:cl.on rorrc

Mr. EJ,.. ird \'&lt;,.,:kc
nr f'.:.._
I \\ 1cr; 1 lcr 'l""[)r Jerernc:-Yates

WRITERS
M

\IJ,-,bdi

UK

l

Ar(I _ !'a~t:

ILi USTRATORS
L1 H~ncy

), re Mir

k~
P ul '-•p,ko" k
l\.t1kc:
~- ,Iosc1 , c ,
D ,-, l ,kroc:.·msk,

l'HOTOl:RAPHERS

~-L

1-"'

\l.•k
' rn:~~LJ

Jo hn Na ughton, M.D.
\'ice Prc"de'll for Climcal AJfa,rs
Dean, School of \ Lhme and Bwmed".al Sciences

&amp;,\-, \'( ''"'

H.ACHl:S:G HOSPITALS
AND LIAIS01'S
o· • \

\ ..tcranir. AJn,

\'c._:'P.uft

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Buff..!o Gcn\.r,.

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( b,IJ,,,-, Ho II • l\.an:n
Fr. ( um1 \1 l, ,I l n· r,
\f'- 0 \1 0 'tl .._,,.

nn"'~u '

\1rn

Dear FellowAlumni/Alumnae:

l➔l

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M,llord F 'lmon- .!, pu ,I,
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fli' &gt;l Ff \:....l PHY-,ICIAN A \l[) BIL'
\lEl11l \~ ,( IEl',,rt,r ,L ,f"i
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fu,.,1 1-\ h\c: t mL ~•· · u~ 11\· "'ip..m~
"-lu1 11Y.r, \ ·u1 r--, f. r v \X.mtcr, 1nJ ii..u
W t • 1-- th 'i&lt;hoc•I.,. \.kJ1o n, mJ
Bmri.l-Ju.. ,1 Sl1cm.1. . ~t.: • l .1 ,er ·\ c•f
i\ic.\ Yn·k lt B -,11 l•f\C. \1am '"itrcc·,
Buffa!~ 1', , for. I,!•; flu-J
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Send
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IE1';T'&gt;f, 16 ( F 5. AdJ,· "
'-t t Buff lo 1', " Y,·l

I

t .s hard ro heltl'\L rh.H my year as pn ..,tdLnt Jf thl' Alumm
Assocaoon 1s .1lrcady ~oming tC',1n end The Sprin~ Cl ,mc.ill
Dav k'Stl\ ttK&gt;s,induding the educ anona, sesstC'ns,ind •he gal,1
e\ent for the reunion c.'as,e,, ,!Tl'Sl't for the \\cekend of Mav 6.
1h,s \e,lf the :-.1edtlJI Alumm Assnc.,ation will stirt a nc\\
award for , medic.ii ,tudent or students \\'1th the highest .ic.ademK
achkvemcnt in their first and se&lt;.ond \cars. It has heLn noted b\
our board th.it studc:tts rc:c.e1vcs,hul,ir,lups upon &lt;:ntmnce to
,choul, but altu rh.,t the: highest 1-h1e\l'rs .tren't honored before
the third year. It is our attempt to recognm: those students.
As mentioned in prtvious \Hl'!ngs, the Distinguished Ahmnu,1A:umna A\1,:,.rd, sponsored 1:-ythe A:umm Assouatt('!'l, will
he presc:mcd rh1s fall Ad nner honormg th·s person will be held
Ill c.Onjun,tton \I 1th our Pa,t Pre,id&lt;.'nts' Dmner. \Xt will h·ep vou
po&lt;ted .1, to rhe winner, .Jnd \1·eexrend an opt:n mva.,tion to ill!
.,!urns to attend the dmner.
In .:losm!l, note thJt 111 the &lt;.&lt;'!"11111!!y~.1r.the Medical Alumn·
\I uh the flepartmenrs of Surgerv
Assoc1anon will c.o-ho,,trc.-ccpt1011s
.,n..l Ant:&lt;tht:si,1 ,,t their 11.it1unalmeetmgs. \Vt: 1m ,te alumm in
the .trca, 0( the nauon.il meetings to .JttcnJ.

1 •l

t IZl4

cJ?d/V ~~
Paul H . \\'icr:bicn

ic c, M.D.

�Vol. 23, No. I

SPRING 1989

Features
0

Theelusive miracle.Heart transplantation

El

A hot new field. Thermography, which maps the

can be
a lifesaving miracle, but the shortage of donor
organs keeps this miracle out of the reach of many.

various skin temperatures on the body, has great
potential in the diagnosis of circulatory and
neurological disorders, say UB researchers.

ffl

Earthquake.
UB physicians offer medical assistance
to victims of Armenia's December quake.

Page 2

lffl BoneGrower.Munro Strong, M.D., associate professor of orthopaedics, pioneered the use in North
America of a revolutionary apparatus for people
with limb deformities and severe fractures .

Page 25

Departments
'1'1 Research. Testing

"clot busters," cutting costs in
trauma cases, and exercises for arthritis of the
knees are subjects of UB researchers.

ffi1 MedicalSchoolNews. You could call them the unsung heros of the school. They're the voluntary
faculty who receive no pay but provide a vital service to the school.

Page 21

Page 12

ml HospitalNews.

iDJ People.The

focus is on Thomas R . Beam, Jr., M.D.,
who's looking at ways to speed up the FDA's drugapproval process, and Peter Ostrow, M.D., Buffalo's
only physician/TV reporter .

Spotlight
. The watercolor work of cardiologist Ivan
L. Bunnell, M.D., Class of 1943, is featured in our
premiere of this department. In each issue, we'll
take a look at the artistic work of one of our alumni, students, or faculty .

Classnotes.

Cover lllurtnrtion: Mike Wolruchinow

��3

FORMANY,
HEART
TRANSPLANTATION
REMAINS
A DREAM
By CONNIE OSWA LD S1DFKO

harles Hilton knew he was going to die soon. Though they didn't
tell him, his doctorsthought he'd die that night. He couldn't eat,
couldn'tbreathe,couldn'twalk. His anginacausedconstantpain. His only hope
was to get a heart transplant."I had nothing to lose,"Charles said. "Anything
would have been an improvement- even death."
Charles was one of the lucky ones. He got a heart in time.
That's the life-saving miracle of heart transplants.
Bue ochers aren't so lucky. Across the country, 20 co 25
per cent of heart transplant candidates die while waiting for
a donor organ, according co Robert M. Mentzer, M.D., director of UB's Heart Transplant Program and a professor of
surgery.
"It's a very serious prob lem," agreed J. N. Bhayana, M.D.,
co-director of the program . "We're losing patients ."
In Buffalo, heart transplants have been performed since
1984, first at the Veterans Administration Medical Center and
now at Buffalo General Hospita l as well.
In chat time, 23 transplants were performed. Five people
died while waiting for a heart, and, as of February, there were
more than iO more patients waiting. Another 15 are being
evaluated as possible recipients .

SPRING 1989

The UB program has excellent facilities, a top-notch staff,
and plenty of willing patients . There's only one shortcoming :
the number of available donor hearts.
One reason for the shortage is that as heart transplantation lost its experimental status, more and more new centers
opened . In 1984, there were only 32 centers in the United
States. Now there are 135 and counting . That's causing keener
competition for the organs.
Another major problem is that people just don't understand about heart transplants .
"People don't even realize organs can be transplanted, or
they don't know which organs can, or they never thought
about donating organs; said Elizabeth A. McNamara, M.S.N.,
R.N., che transplant coordinator for the Organ Procurement
Agency of Western New York.
"Then they're faced with the sudden, tragic loss of a loved

BUFFALOPHYSICIAN AND BIOMEDICALSCIENTIST

�4

obert M. Mentzer,
M.D., director of
UB's Heart Trans,
plant Program:
"We have to try to think in
terms of not wasting organs."

one, and when they' re asked
if they want to donate his
organs, they may say 'nd
because they're not ready to
deal with it."
McNamara pointed out that
the best organ donors,
especially for hearts, tend to
be young, healthy people who
suddenly suffer brain death.
It's the guy whose motorcycle spun out of control. Or the one
who fell during a fist fight and hie his head on the sidewalk.
Or the child who walked out between two parked cars.

"That's the rub~ she said. "These aren't predictable deaths.
The family has just lose a loved one they may have been speaking to a few hours earlier."
And the idea of brain death is difficult for families.
"It's rough for the family to accept chat their beloved one
has died," said Bhayana, associate professor of surgery at UB.
"But if they wait too long, the heart may stop or there might
be an infection of the lungs. Then the person is no longer
a candidate for donation ."
"Even within medicine and nursing, you'd be amazed at
the number of people who are nor comfortable with the term
'brain deach:" added McNamara . "They chink, 'Well, maybe
the person's not reallydead .'" Exacerbating the problem is the
fact chat there's no Scace-wide criteria. Instead, the Stace has
empowered each hospital co decide how many flat EEGs and
ocher evaluations constitute brain death .
Because chis is such a trying moment, hospital staff
members are often reluctant to approach che family about

SPRING 1989

possibly donating organs .
"Some of the professional
staff take it on themselves not
to ask the family, chinking the
family won't be able to handle
the
emotional
strain,"
McNamara said. "Bue chat's
nor fair to chem-we need to
give chem rhe opportunity to
say 'yes' or 'no?
"In the IS years I've been in nursing, it's the hardest thing
I've ever done. But there's also a redeeming aspect. le helps
them go through the grieving process. And it helps chem build
a kind of memorial co their loved one to know chat he or
she has given three or four people a second chance at life (if
several organs are recovered).
"I just spoke with a mom whose daughter died in a car
accident. She calls every so often to talk . The daughter was
an only child and chis was the parents' first Christmas without
her . They got through it because they thought of the people
who could go on living. They were very happy they gave consent."
Boch the Scace and federal governments have now
passed laws chat mandate chat families of suitable organ
donors muse be given the opportunity co donate, McNamara
noted . Every hospital has designated a key person who will
be the one co approach the family when brain death is
imminent .
While a person is still well, he can sign a donor card pledging his organs at his death, or sign che special space on the
back of the New York State driver's license. These are considered legally binding .
BUFFAID PHYSICIANAND BIOMEDICALSCIENTIST

�5

N. Bhayana, M.D. , codirectorof UB's Heart
Transplant Program:
• "It's a very seriousprob­
lem. We're losing patients."

But the most important
thing he shou ld do is let his
family know his wishes, said
McNamara, because the agency won't accept an organ
without the family's consent .
"Ir's great to carry the donor
card around with you, but if
your family doesn't know
anything about your decision,
it's worthless," she said.
Because of the high level of emotion that may be involved,
the agency won't accept the donor if there is overwhelming
family disparity .
"We don't want to cause a permanent emotional rift in
the family," she explained . In addition, the bad feelings it
would generate would work against the agency.
"If you turn off one member of one family, and that person tells the story to 50 or 100 people, it turns all of them
off; McNamara said.
If there is no known next of kin, the agency won't accept
the donor .
Some people are reluctant to give consent because they
hold misconceptions . The agency tries to overcome this problem by assuring the family that donating organs won't cost
them any money, that it won't mutilate the person, that they
can still have an open casket funeral, and that major religious
denominations allow organ donation .
Still another reason for the shortage of donor hearts is
the small geographic area from which they can be drawn . The
average maximum ischemia time is four to five hours; that
is, the donor heart can be without blood flow for only four
BUFFALO PHYSICIAN AND BIO~EDICAL SCIENTIST

to five hours from the time it
is removed
until it is
transplanted . That limits the
distance the transplant team
can travel to recover a heart .
Another factor that may
aggravate-or
alleviate-the
shortage of donor hearts is a
new distribution system that
started in January . Those involved agree that it's still too early to tell how it will affect
Buffalo's program .
Under the new system, if a heart is available in Buffalo,
the Organ Procurement Agency of Western New York contacts the University transplant program . If there is a suitable
recipient at Buffalo General or the VA, the organ stays in
the area. (fhe donor heart must be compatible in a number
of ways, including size and blood group.)
If the Buffalo program can't use the heart, the local procurement agency contacts the United Network for Organ
Sharing (UNOS), a national network . That group runs a computer match to find a recipient within a 500-mile radius of
Buffalo. Out of all of the suitab le candidates, the person who
has been waiting the longest gets the organ .
But what happens if a donor heart is available in
Rochester or Syracuse or Albany, cities which don't have their
own transplant programs? Under the old system, a candidate
first would be sought within New York State, so Buffalo would
have a good chance of getting the organ .
Under the new system, however, the organ goes to the
candidate within a 500-mile radius who has been waiting the
longest . Ir's feared by some that out-of-State centers will get
srrui-o 1989

�Say
6

lizabeth A. McN a~
mara, M.S.N., R.N.:
Hospital staffs often
......... are reluctant to ap~
proachfamiliesabout donating
organs.

many of the hearts that,
under the old system, would
have been sent to Buffalo. People are also concerned chat
these centers won't reciprocate
and send hearts ro Buffalo
because these ocher centers
are larger and able to use
every heart that becomes
available in their local areas.
"Because the system is changing-we hope it's changing
for the better-we're not sure how these changes are going
to affect our programs;' said Mentzer. "But we all share the
same goal, which is to gee as many donor organs to as many
patients as possible, no matter where they live.
"We're always talking about the patient, but equally important is protecting the donor supply. We have to cry to think
in terms of not wasting organs, and placing the donor organ
in an environment that has the best chance of being successful, because there is such a demand."
Still anothe r factor contributing to the shortage may be
the sheer newness of everything surrounding heart
transplants. Western New York has had a system for procuring hearts since only 1983, Bhayana pointed our . Before chat,
each hospital acted on its own. And since the University program is so new, it doesn't yet have rhe community awareness
and support that other, more established programs have,
Mentzer added.
Predicting the future of organ procurement is difficult .
New problems may crop up. For instance, the spread of AIDS
may cut into the supply of donor organs in the future,
Bhayana and Mentzer speculate.

SPRING 1989

For now, a number of solutions to the shortage are being examined. Researchers are
looking for ways to increase
rhe length of time rhe donor
heart can be without blood
flow, as has been done with
livers. Livers once had to be
transplanted
within eight
hours, but now a perfusion
solution has expanded that time frame to 24 hours, allowing
chem to be distributed all over the country, McNamara said.
Also, the maximum allowable age for heart donors has
increased, Mentzer pointed out. It's now 40 years old for males
and 45 years old for females. Organs from older people aren't
accepted because it raises the chance of implanting a heart
with coronary artery disease.
The key solution to the shortage, Mentzer, McNamara,
and Bhayana agree, is education of both medical staff and
lay people.
Ir's important to educate the smaller, rural communities
around Buffalo, said Bhayana, such as Jamestown, Olean, and
Warsaw.
"Thar's where we're going to have our donors;' he
predicted.
"We're trying to get a foothold into the community,
especially into the minority community, through the clergy
who deal with death and dying every day;' McNamara said.
Many minority people have strong religious beliefs, she noted,
and if their minister stands up in the pulpit and endorses
organ donation, the efforts will trickle down .
The organ procurement agency also conduces free

BUFFALOPHYSICIANAND BIOMEDICALSCIENTIST

�7

harles Hilton
pends on a suitcasefull of medication,
but he and hisfamily see his transplantas "a gift
of life and God's miracle."

workshops and seminars, and
will make presentations to
clubs and "anyone who's willing to listen," she said. "We're
always in need of additional
media attention."
"I want to emphasize chat
the media has to help us
educate peop le," Bhayana added. "If someone is brain dead,
his family owes it ro society at large to use his organs ro save
somebody else. Thar's what will he lp us."
Mentzer pointed out that it's important to get across the
idea that organ donations have the potential to save a life.
"As long as we can continue to emphasize how important organ donation is, and what the benefit is, we can
separate the tragedy of the death from the goodness of the
gift," he said.
"It's a gift of life and it's God's miracle,"says Martha Hilton,
Charles' wife. "There are miracles."
Sept. 2, 1986 was Charles' 54th birthday. And it was a
birthday in the true sense of the word because that was the
day he receiveda new heart at the VA and a new chance for
life.
Charles' heart camefrom a 17--year-old
killed in an all-terrain
vehicle accident.
"That was the one sad part-that someone had to die to let
my husband live," Martha said.
The desperatelyill patients waiting for transplantspray for
hearts, Charles said; not hoping that someonewill die, but hoping
that if someonedoesdie, the heartcomesin time to save their lives.
It's difficult for them to wait day after day wonderingif they'll

BUFFALOPHYSICIAN AND BIOMEDICALSCIENTIST

survive long enough to receivea
heart. One fellow Charles knew
waited three years without getting a heart. A couple of his
friends have been waiting six
months. Charles had an
unusually short wait-only a
week.
It's been about three years
since his transplant at the VA,
and Charles,a retiredapartmentsuperintendent,sayshe feelsgreat.
He walks a couple of miles a day in the winter and 10 miles a
day in the summer.
A new endeavoralso keeps him busy. Knowing how difficult
it was for his family to commute almost three hours from his
daughter'shome in Naples, N.Y., to the VA,Charles hasambitious
plans to open a housein Buffalowherefamiliesof out-of-townheart
transplantpatientscan stay at no cost. He speaks to veteransgroups
lookingfor donations,which can be sent to him at 18 Mark Circle, Naples, N.Y., 14512.
Gratefulfor the secondchancehe got, Charlesalsodoespublic
speaking on behalf of the Organ ProcurementAgency of Western
New York. Through the agency, the Hiltons sent a letter to the
family of the teenagedonor, thanking them for chisextraordinary
gift.
"Everytime my husbandhasa birthday, their son hasa birthday, too," Martha said.
•
Editor's ::-..'ote:
For more infonnac1onon che Organ Procurement Agenof Wbtcm ::-..'ca)ork, Inc., call I-800-227--1771.
For more information on ihe UB!Bujfa/o General Heart TransplantCenter, call
1-800-2-12
00-15.
C\'

SPRING 1989

�8

SPRING 1qgq

BUFFALOPHYSICIANAND BI0~1EDICALSCIENTIST

�THERMOGRAPHY:
A HOf NEW FIELD
By CONNIE OSWALD STOFKO

he patient's image appearson the computer
screenas blotchesof garish reds, blues, and
greens,lookinglike a wild paint-by-numbers
.
The facial features are indistinct, but that doesn't
matter. This picture is more like a map than a
portrait.
The picture was created using a technique
called thermography,which maps the various skin
temperatures on the surface of the body.
This data on distribution of skin temperatures
has great potential in the diagnosisof circulatory
and neurologicaldisorders,say UB researchers.
And
they're ready to take the lead in the new and growing field of thermography.
"Currently, we are the most active center for
thermographyresearchin the country and are expanding rapidly," said Michael Anbar, M.D.,
chairmanof the Departmentof BiophysicalSciences
at UB. "We've got cameras matched by nobody.
We've got software matched by nobody-because
we developed it.
"We want to make Buffalo the national center
for thermographyresearch."
BUFFALOPHYSICIANAND BIOMEDICALSCIENTIST

SPRING 1989

9

�T

hermography is a relatively simple
technique.
"It's ve r y much like taking a
10 photographic image-the re's a camera , it
looks at you, it takes your picture. You
can even smile if you want to," Anbar
quipped.
The camera is a rectangular , black
metal box about two feet long. A spinning mirror located in a recess of the box
picks up the light reflected from the surface of the subject . The light is reflected
to another mir ror inside the box, and
then to a third.
Finally, the lighr is reflected inside the
box onto a detector rhar's sensitive to infrared light. (Everyone emits infrared
light. Broadly, it can be said that the intensity of the infrared light depends on
the temperature of the subject.) The
detector changes its resistance depending
on the temperature char falls upon it.
If a photo detector were used in place
of this infrared detector, you'd get a
photographic image, Anbar noted . Using the thermographic camera, vivid color images that show the distribution of
skin temperatures are produced on a
computer screen, displayed in colors
ranging from hot red to cold blue.
Since skin temperature is a function of
the pe rfusion (or blood flow) under the
skin, hot and cold spots can indicate
problems wirh blood vesselssuch as clogging of the arte ries, thrombosis, or an inadequate blood supp ly to the feet of
diabetics.
"Whenever you have a perfusion problem, thermography is ideal because it's
non-contact, non-invasive to the extreme, it doesn't hurt, you can repeat it
as many rimes as you like, and you can
quant icace the resulrs; said Anbar .
"I feel we haven't scratched the surface
of its potential:'
Changes in skin tempe rature and
blood flow can indicate more than circu latory problems. Since blood vessels
can constrict or dilate depending on
signals from nerves, we can learn about
the behavior of nerves by watching the
behavior of blood vessels, Anbar explained. Thermography cou ld be used to
flag a pinched nerve or a disorder of the
sympathetic nervous system .
Thermography can also be used to

SPRING 1959

"visualize" pain. That's because when a
nerve sends a signal to the brain that
registers as pain, it's often associated with
a change in blood flow.
If the affected area of the body shows
a change in temperature, it might indicate that the patient feels pain .
However, even if nothing unusual shows
up on the thermographic image, the
perception of pain can't be ruled out.
While this technique can be very
helpful in rehabilitation medicine, it also
can be abused, Anbar pointed out .
Lawyers like to use it when they suspect
that a litigant is faking an injury in order
to collect money after an accident.
"T he r mography has fa llen into
disrepute because it has been used so
much by the legal profession as a kind
of lie detector for pain," Anbar noted.
While thermography is now used most-

ly in non-surgical procedures, it has great
potential for use during surgery, Anbar
believes. le could be used in all surgical
procedures where perfusion is critical,
such as during organ transplants .
"Here's a non-contact technique char
tells you whether perfusion is uniform,
and it could be performed du ring
surgery," Anbar said.

T

he University researchers are investigating ways that thermography
can be used to assess irritation to the cornea and to try to prevent the rejection
of corneal transplants . Thermography
could also be used to check on the healing of skin grafts.
The researchers are developing new
computer hardware and software for
thermography, as well developing better
diagnostic tests.

0 EGREES CENTIGRADE

32.4

32.0
31..7

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31..4

..

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30

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I
''ffjl
•'

7

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30

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ii.

BUFFALO PHYSICIAN

�They want to take the subjectivity out
of thermography. Instead of simply looking at a thermographic image and making judgments about "hot" and "cold"
spots on the body, the researchers want
to be able to assign number values to the
data .
"We're focusing on quantitation of
rhermographic information;' Anbar
noted . "Ar the moment, we're the only
ones in the count ry doing this."
The researchers also are crying to
develop "normative data; chat is, data
from healchy people to provide a baseline
for comparison co different pathologies.
They hope to use rhermography as a
model for diagnostic imaging in general.
T he data they're developing may be applicable to any diagnostic imaging problem, from X-rays to ultrasound.
"An image is an image, no matter how

it's generated," Anbar noted.
The UB team is an interdisciplinary
group char includes :
• Robert A. Spangle r, M.D., Ph.D.,
associate professor of biophysical sciences
at UB
• John Loonsk, M.O., instructor in
biophysical sciences at UB
• James Montoro, biomedical engineer
in biophysical sciences at UB who is
developing quantitative techniques
• Kyu-Ha Lee, M.D., associate professor of rehabilitation medicine and
director of the residency program in
physical medicine and rehabilitation at
UB as well as chief of rehabilitation
medicine at the Veterans Administration
Medical Center
• Linda A. Hershey , M.D., Ph.D.,
associate professor of neu rology at UB
and chief of neurology services at the VA

• Steven M . Steinberg, M.D., assistant
professor of surgery at UB and chief of
the surgical service at the VA
• William H . Coles, M.D., M.S., professor and chairman of ophthalmo logy
at UB and clinical director
of
ophtha lmology at the Erie County
Medical Cen ter.
A relatively new field, computerized
rhermography has existed for only about
IO years. Buffalo's first rhermography
camera arrived at the Veterans Administration Medical Center less than
three years ago. Buffalo now has three
such cameras-two at the Veterans Administration Medical Center and one in
the Department of Biophysical Sciences
at UB . By 1992, Anbar hopes to have
seven or eight in the area.
The Department
of Biophysical
Sciences decided to put a great deal of
effort into thermography because it's a
problem researchers here can attack with
relatively inexpensive equipment, Anbar
said. For example, an MRI (magnetic
resonance imaging) machine costs about
$2 million to buy and $1 million to run.
Thermography equipment costs about

$100,000.

T hese gra:,•-sca le
th e rm og raphi c im ages show th e
hand s of a pa ti ent
s uff e rin g f ro m a
neur olog ica l
di so rder. T he han d
at left is co ld er
. than th e on e a t
·; right.

A NO BIOMEDICA L SCIENTIST

"We cannot easily become leaders in
areas which require larger investmentsand we should be leaders; Anbar said.
"With chermograp hy, it's not a 'me-tod
situation . Thermography is one of those
areas where we have an advantage over
anywhere else in the coun tr y."
Hardly a bargain-basement techniq ue,
thermography can do things that other
techniques can't . Thermography looks at
the functions of the body, while othe r
techniques, such as X-rays and MRI,
look at the structure of organs or tissues.
The rmography assesses the surface of the
body, while the ochers look inside the
body . All of the tech niques operate differently and the information each provides comp lement one other.
"Thermography is not a substitute and
it's not a competitor to these ocher
techn iques ; Anbar emphasized. "They're
very different.
"Thermography can identify physiological phenomena that can't be identified by other means . T here's no simpler,
more direct way to measure" some of the
functioning of the nervous system. •

SPRIN G I9S9

11

��FromDestruction
to Recovery
B

y

M

A

The Armenian

R

K

MARABELLA

rom their devastated homeland in the moun-

earthquakein

tainous region of Armenia, 10 young earth-

December
devastated

quake victims arrived

at snowy Buffalo

cities and

International

killed 50,000

Airport in February for treat-

people. But for

ment at Children's Hospital of Buffalo and

survivorslike
MartinMekret-

Millard

Fillmore

Hospital-two

major

chian, left, life
goes on-with
help from

hosp itals affiliated with UB's Schoo l of Medicine

and

Biomedical Sciences.

some UB
physicians.

Children's
treating
youngsters,

seven

H ospital

is

Armenian

more than

any

other American hospital. The
children range in age from 5 to 14. UB physicians affiliated
with the Hand Center of Western New York at Millard
Fillmore are treating a 17-year-old and two Armenians

in

their early 20s.
BUFFAW PHYSICIANAND BIOMEDICALSCIENTIST

SPRI!'&lt;
G 1989

13

�14

Munro Strong, M.D., associate professor in orthopaedics at UB and orthopaedic surgeon at
Children's Hospital, was one of a team of 10 American
medical personnel who traveled co Armenia for the
difficult cask of choosing which patients were co be
airlifted to the U.S. for continuing medical treatment.
During his nine-day stay in Armenia, he and physicians from Syracuse, Boscon, Philadelphia, and
Chicago, in cooperat ion with Armenian officials,
selected a coral of 37 patients for treatment in 10
American hospitals . The Armenians were chosen for
medical treatment in the U.S. if their injuries were liferhrearening, infected, or healed improperly, according
to Strong . Many will receive prostheses and rehabilitation during their stay.
"Ideally, you would like co help all of the children
and bring them all back co the U.S.," acknowledged
St rong . "Unfortunately, we can only directly assist
relative ly few of these kids, but these kids we help will
gee excellent medical care here."
An est imated 3,000 to 4,000 Armenian chi ldren
are suffering from serious injuries including broken
spinal cords, crushed pelvises and limbs, and infected

SPRING 1989

fractures . The earthquake, which hit two and a half
weeks before Christmas, claimed the lives of more than
50,000 men, women, and children . Those who have
survived or sustained injuries have lose others in the
catastrophe .
"The children who made th is trip are extremely
frightened; Strong emphasized . 'They have been
through a great deal. Most of chem in face have lost
one or both of their parents. Many of their parents
were never even found. Many who came co the U.S.
were accompanied by an older sibling, an aunt, o r a
grandparent as their guardian ."
Buffalo became involved in treating the Armenians
through Robert Gillespie, M.D ., acting chair of orthopaedics at UB and chief of orthopaedi cs at
Children's . On Christmas Eve he received a phone call
from officials of Project HOPE, an independent, nonprofit, international, health education foundation
lilit Ermand- based in the U.S.
Both G illespie and Strong had worked with Projian, S, left,
ject HOPE as orthopaedic consultants to the Pediatric
Institute of Krakow, Poland for the past two years. The
radiates suninstitute is the largest hospital for children in the world
shine. Below:
and is affiliated with Project HOPE's continuing education of Polish and Soviet medical personnel.
ArevikToroProject HOPE had been contacted by cop White
House
officials following Soviet Premier Mikhail Gorsian, 13, and
bachev's request for aid from the U.S.
SonjyPangoian,
Strong emphasized char the airlift and treatment
of the Armenian child ren is merely an initial gesture
17, are mesfrom Project HOPE, which negotiated a more enduring
relief initiative with the Soviets and their Ministry
merizedby
of Health. The long-term project includes plans co
Americansoap develop a rehabilitation facility in Yerevan (the capital
of Armenia located 3 7 miles from rhe site of the
operas.
catastrophe)
in cooperation
with Armenian
authorities .
Initially, the facility will provide services co earthquake victims requiring continuing treatment for their
injuries. Children fitted with prosthetic devices in the
United States will need co have them mod ified as they
grow. The project will include training technicians co
operate the Yerevan facility and establishing an or-

BUFFALO PHYSICIAN AND BIOMEDICAL SCIENTIST

�chopaedic and plastic surgery exchange program with
American hospitals and universities.
"There is no ability co make prosthetics or
rehabilitate people with upper-extremity loss in
Armenia," noted Strong. "All of the children who had
injuries of upper or lower limbs were left unsplinted,
so chat the patients we found who had upper extremity
nerve injuries had their joints contracted in one (contorted) position or another."
There is a great dea l lacking in the medical expertise of the Soviet Bloc as well as the Eastern nations
in general, Strong said. He reported that he did not
see one spline of any kind the entire time he was in
Armenia .
"Many concepts considered basic to medical care
are not known or regarded there-such as the need
for splines or removal of infected bone without the
need for amputation," Strong pointed out .
Nevertheless, he emphasized chat the Armenians,
given the available facilities, did a "remarkable and
massive job caking care of the hundreds of thousands

of injuries chat literally came into Yerevan within the
first several days."
It's hard to envision the devastation of the quake .
In Leninakan, a town with approximately 200,000 inhabitants, officials blew up unsafe buildings every day
at 4 p.m. and dragged the rubble outside of town,. In
Spicak, a town of 30,000 chat was very close to the
epicenter of the quake, 50 per cent of the buildiings
were destroyed and the other ha lf were unsafe . T hose
who survived had to be evacuated .
"In a small village of about 2,000," Strong sob1~rly
recalled, "the entire place was leveled. Not a single
structure was left standing. There was simply a pile
of rubble for about two miles along the highway .
''Any medical system, no matter where it might be
located, would be overwhelmed by such an event. The
people there worked night and day in order co save

BUFFALO PHYSICIAN AND BIO MEDICAL SCIENTIST

few were as

15

lucky as Artem
Horontyunian,
below, who
traveled to
Buffalowith
his mother.The
girls at right
check out
Polaroidsof
themselves.

lives."
Strong urges people, particularly in ArmenianAmerica n communities, to continue opening their
hearts and responding to the needs of the Armenians.
Buffalo's Ronald McDonald House, which affordab ly
houses our-of-town families of patients who have
traveled co Buffalo for medical treacmenc, has graciously opened its doors co the parents and guardians of
the Armenian victims. Moreover, all of the hospital
services, equipment, and the medical attention given
by the Americans have been donated without charge
to the victims or their government .
"le is a tribute to the quality of medical care
available in Buffalo,"noted John P. Naughton, UB vice
president for clinical affairs and dean of the medical
school, "chat UB physicians working at two of our major affiliated hospitals will treat the largest number of
children-IO-airlifted
from Armenia .
"It is also a tribute co Buffalo's reputation as The
City of Good Neighbors' chat it will play host to the
families and guardians of these young patients?'
UB President Steven B. Sample commented that,
"shortly after the Dec. 7 catastrophe, the University
at Buffalo was able to lend engineering and technical
expertise to the people of Armenia through our National Center for Earthquake Engineering Research.
We are pleased to be able to continue this international
commitment through our participation in Project
HOPE's humanitarian program?'
•

SPRING 1989

�16

BO
GRO

R

This one device can lengthen or straighten a
limb. It can grow strong, healthy bone in the gap
left by the removal of infectedbone. And it can
do it better and faster than other treatments,
says the UB orthopaedist who pioneered its use
in North America.
By MARK MARABELLA
lthough its appearance may
resemble a gruesome medieval
torture device, nothing could
be further from the truth . Called the
Monticelli-Spinelli External Fixation
System, this apparatus of stainless steel
wires, nuts, and rods is a revolutionary
system which has given new hope to patients with limb deformities and severe
fractures.
"The European
company
that
manufactures this device didn't realize
the importance of what they had:
asserted Munro Strong, M .D., an
associate professor of orthopaedics at
UB. "I had a difficult time convincing
them to increase its production and
distribution for use in the States.
"This one device can be used to correctangular deformity and limb length,
abnormal growth, and rotationa l adjustment."

A

•

SPRING 1989

Ant hony H int o n

It has been used for patients who need
to lengthen one leg that is shorter than
the orher, to straighten a leg that is
crooked due to abnormal growth, or to
grow healthy bone in the gap left by the
removal of an infected bone segment .
Ocher devices aren't able ro perform so
many diverse functions, Strong noted.
Furthermore, they require more extensive surgery and often require rhe use of
plates or grafting, which result in weak

BUFFALOPHYSICIANAND BIOMEDICALSCIENTIST

�17

and britcle bones that are more susceptible to fractures.
The Monticelli-Spinelli device requires
a shorter treatment period than other
devices, with only a brief stay in the
hospital when the device is initially attached. The device is monitored and
cleaned by the patient daily, requiring
only intermittent examinations by the
attending physician. Furthermore, the
device allows the patient to put weight

BUFFALOPHYSICIANANO BIOMEDICALSCIENTIST

on the limb with only limited
restri,ctions.
"The most impressive feature of this
devic,e is its ability to develop new strong
and healthy bone, with few postoperative complications; emphasized
Stronig, who is also an orthopaedic
surgeon at Children's Hospital of Buffalo.
Once Strong convinced the manufacturers of the device's importance, he and
Robetrt Gillespie, M.D., acting chair of

orthopaedics at UB and ch ief of orthopaedics at Children's, were the first
surgeons in North America to implement the device in October 1987.
Children's Hospital was chosen as one of
four initial North American sites to be
study centers for the instrument,
manufactured by Jaquet Orthopaedic,
S.A., in Geneva, Switzerland, a subsidiary of the Howmedica Company.
Just two years later, there are 43 centers

SPRING 1989

�18

across the U.S. and Canada, and more
than 200 patients have benefited from
the system-IS alone have been treated
at Children's Hospital.
For Anthony Hinton it meant that not
only could he avoid the amputation of
his bad ly ipfected leg, but he can also
look forward to a full recovery.
"This device is one of the greatest inventions I know," declared an enthusiastic Hinton . "I didn't think this
thing was going to work, but now I'm
happy to see that it really has ."
Hinton suffered a bad ly broken tibia
(the thicker of the two bones in his lower
leg) when the tractor trailer he was driving flipped over and pinned him inside
the cab. A lthough his leg was set and
placed in a cast, he developed an infection within the fracture of his bone
several weeks later. This meant that Hinton had to undergo surgery to remove
the portion of infected bone .
In the recent past, this type of operation meant that the patient might lose
the full use of the limb or would have
to have it amputated . But that's not the
case with the Monticelli-Spinelli device.
The stainless steel device is composed
of two or three concent ric rings which
encircle the limb, stabilized by three vertical rods which look like long bolts.
Wires, attached to the rings, hold the
severed bone in place and provide che
necessary traction tension . Nuts are attached to the rods. As the patient
tightens the nuts, the device, and in turn
the leg, is stretched .
Strong used the device in a technique
called proxima l corticotomy in Hinton's
case. Once the infected portion in Hinton's lower tibia was removed, a cut was
made in the proximal metaphysis (the
growth plate in the tibia closest to the
knee). Within this incision, a hematoma
(a blood-filled swelling) formed, which in
time changed to fibrous tissue, and then

SPRINC 1989

Hinton had lost about 1112centimeters
(.6 inches) due to bone absorption in addition to the 4 centimeters (1.6 inches)
of infected bone removed by Strong. So
Hinton had his leg lengthened almost 6
centimeters (almost 2.4 inches) co compensate for the bone he lost.
Hinton was required to tighten the
nuts only a quarter millimeter (about .01
inches) four times a day for six months .
This he lped to stretch the healing bone
tissue gradually. To prevent infection,
which is common in such cases, each day
Hinton had to carefully clean the wires
which pierce the skin .

"I didn't think this
thing was goingto
work, but now I'm
happy to see that it
reallyhas,"said
Anthony Hinton. "The

pain was minor compared
to the benefitsI
received.Even thoughI
couldn'twork, I could
still get aroundand put

T

he device is most often used on
younger patients because of their
ability to heal and regenerate new bone
faster. However, Hinton, at 28, is the
oldest patient in North America to have
used the device thus far.
"The doctor cold me that I was the
oldest patient, but that didn't bother me;
recalled Hinton . "The pain was minor
compared to the benefit s I received from
this thing . The only pain involved was
when I had to tighten (the nut s) or if I
bumped it by mistake. The cold weather
during the winter wasn't too pleasant
either, but I got used to it.
"Even though I couldn't work, I could
still get around and put weight on it,"
Hinton added. "My mother made me a
special pair of pants to wear for the
winter, and I slept with pillows under my
leg."
Although Hinton stopped tightening
the nuts after six months, he continued
co wear the device for two and a half
more months to give the new bone,
muscles, and tissues in his leg a chance
to strengthen. Now that the wires are
removed, he will wear a cast for about
six to eight months, according to Strong.
"There was some inconvenience, buc
•
now my leg is fixed," said Hinton.

weight on it. There
.
.
was some inconvenience,
but now my leg is fixed.''
into solid bone.
As the incision in the metaphysis
gradually began to regenerate new bone,
Hinton tightened the nuts . That increased the length of the growing upper
tibia and moved it toward the lower portion of the tibia. Eventually, the gap
caused by the removal of the infected
bone became narrower . Finally, the upper and lower port ions of tibia met,
fused together, and became solid .

BUFFA LO PHYSICI A N A ND BIOM EDICAL SCIENTIST

1

�Alumni &amp; Et•ents

19

AWMNISETAWARD
FORTOPSTUDENTS
he Medical Alumni Association
Academic Achievement Award has
been established ro honor the third-year
student or students who have achieved the
highest academic standing during their first
two years of medical school.
The Medical Alumni Association began
the award because it was felt that while many
awards and scholarships are offered to
students when they enter medical school,
based on their undergraduate records,
nothing is done to recognize the top scholars
before their third year of medical school.
The achievement award will be presented
for the first time during the school's annual
awards ceremony for students in August . •

T

REHAB
MEDICINE
sm SYMPOSIUM
he Department of Rehabilitation
Medicine at UB is sponsoring a symposium on "Functional Assessment in
Rehabilitation Medicine" to be held July 8-9
at the Marriott Hotel in Amherst .
The conference will discuss measurement
of the disability of patients in rehabilitation
programs and how this scaling is developed
and used, said Carl V. Granger, M.D., professor of rehabilitation medicine at UB and
head of rehabilitation medicine at Buffalo
General Hospital.
Ocher topics will include the implications
of medical ethics, the implications of financing, and the implications of research.
The symposium is geared to physicians,
nurses,
therapists,
social
workers,
psychologists, and administrators involved
with chronic health care services or medical
rehabilitation health care services.
The cost of the symposium is $195.
For more information, write to Granger at
the Department of Rehabilitation Medicine,
Buffalo General Hospital, 100 High St., Buffalo, N.Y~14203.
•

T

'l

ticipated in the famous Framingham Study.
Lasting almost 30 years, it is the longest continvovs swdyof c;:an;liovascular
disease. Much
of what we know about strokes has come
from this study.
Speakers from UB are Linda Hershey, M.D.,
Ph.D., associate professor of neurology, and
William Kinkel, M.D., professor of neurology.
Organizers of the symposium arc Glen E.
Gresham, M.D., professor and chairman of
rehabilitation medicine at UB; Carl V.
Granger, M.D., professor of rehabilitation
medicine at UB, and John V. Basmajian,
M.0., professor emeritus of medicine and
anatomy at McMaster University in
Hamilton, Ontario.
The conference is funded through a grant
from the National Institute on Disability and
Rehabilitation Research, part of the U.S. ·
Department of Education.
Ir's a feather in the cap of the University
to be chosen to host this international symposium, said Gresham, who noted that UB's
research in chis field is strong.
•

REMEMBERING
YESTERYEAR
emember what it was like when you
were at UB-the classes, the parties, the
friends?
The Alumni Association wants to capture
a bit of chat feeling through a collection of
memorabilia to be housed in a locked display
case in the LippschuczConference Room in the
medical school.
The association is looking for alumni to
lend or donate items for display. Items might
include pictures, small medical equipment,
programs, pennants, buttons, or other
souvenirs that remind you of your academic
and extracurricular activities.
Send items to Dr. John Richert, Alumni
Affairs Office, 146Cary-Farber-Sherman Addition, State University of New York at Buffalo, 3435 Main Street, Buffalo, N.Y. 14214.•

R

CALLFORNOMINATIONS
our president and Board of Go vernors
has, over the past several years, received
many requests for Alumni / ae to
establish a Distinguished Medical Alumnus / a
Award. Therefore, your president and board
are seeking nomination s for thi s award to be
presented annually beginning thi s year.
The award will be presenced to a graduate
who has distinguished himself/ her self nationally or internationally in the eyes of
his/ her peers and has made an outstanding
contribution to medicine, the arts, or
humanity during his/ her career.
The selection will be made during the summer and the award will be presented in the
fall at a special award dinner.
Please forward the name of your nominee
as soon as possible on rhe atta ched card. A
June 30 deadline has been established for the
receipt of all nomination s. Your cooperation
is absolutely viral if this is co be a true alumnus / a award.

Y

WORLD
EXPERTS
TOMEET
ATUB TODISCUSS
STROKE
any of the world's experts in stroke
outcome research will gather in UB's
Center for Tomorrow July 10-12for
an international symposium on "Methodologic Issues in Stroke Outcome Research~
Attendance at the symposium is by invitation only.
The proceedings will be published by the
American Heart Association as a supplement
to Stroke: A Journal of CerebralCircularion.
The speakers will come from the United
States, Canada, Australia, Japan, Israel, and
Great Britain. They will include two who par-

M

SPRING 1989

BUFFAID PHYSIC IAN AND BIO MEDICAL SC IENTIST

-

---- --------

��I
Research

21

Testing 'Clot Busters'
Simple blood test may do the trick

'

By ARTHUR PAGE
simple blood ccscmay provide an alcernacive co immediate coronary arceriography when it comes co determining
whether medications have successfully
dissolved blood clots in coronary arteries
following a heart attack, according to researchers at UB.
The researchers showed chat the test, which
measures proteins released into the bloodstream by cells in damaged heart muscle, was
88 per cent accurate. While the test was
already available commercially, the researchers were the first co use it for this purpose.
It's essential co determine whether rhe
blocked arteries have re-opened in order co
plan a patient's treacmenc. That determination now relies on coronary arteriography, an
expensive and invasive procedure nor
available in all hospitals nor at certain times
even in chose with cardiac cathecerizacion
laboratories.
Unlike coronary arteriography,
the
commercially-available blood test is inexpensive, noninvasive, and relatively risk free.
Results of the research, conducted in con•
junction with scientists at Emory University, were reported in che December issue of
Circulation, the scientific publication of the
American Heart Association.
Avery K. Ellis, M.D., Ph .D., UB assistant
professor of medicine, was principal investigator for the study, funded by the
Veterans Administration and American
Heart Association. Ellis is chief of cardiology
at Buffalo Veterans Administration Medical
Center.
His UB co-investigato rs were Francis J.
Klocke, M.D., who is the Albert and
Elizabeth Rekatc Professor of Medicine as well
as chief of cardiology at UB and che Erie

A

.

BUFFALOPHYSICIANAND BIOMEDICALSCIENTIST

Unlike coronary
arteriography,
the

in a cardiac cachecerization lab.
He noted, however, chat "most of the patients chat have infarcts are in hospitals where
cathecerizacion labs are not available. Even
if they are in a hospital with a cachecerizacion
laboratory, you could not logistically make
immediate cathecerizacion routine wichouc
greatly expanding the facilities and personnel."
On the other hand, che blood cescused by
the UB and Emory researchers can be used
in all hospitals.
The researchers are the first co focus on
measuring myoglobin, an oxygen-carrying
protein essential to the heart's normal functioning, co gauge che success of thrombolycic
therapy, according to Ellis.
They focused on the myoglobin level in
blood samples taken from 42 patients at the
time they received a thrombolytic drug and
at regular intervals thereafter. The subjects
also underwent cardiac cathete rizacion co
assess the success of chrombolycic therapy.
There was a rapid rise in blood myoglobin
levels in patients in whom the drugs resulted
in reperfusion. In contrast, che levels rose
slowly in those in whom the attempt co open
the artery was unsuccessful.
The researchers found that a co mparison
of myoglobin levels in a blood sample taken
ac che time medication was given and one
taken two hours lacer corre lated with the
resulcs of reperfusion attempts, as confirmed
by coronary arreriography, 88 per cent of the
time.
"The need co develop a non-invasive marker
of reperfusion is important in view of the large
number of patients in whom intravenous
thrombolysis is now likely to be used and in
whom subsequent triage becomes an important issue; they said.
•

commercially~available
blood test is inexpensive,
noninvasive,and
relativelyrisk free.
County Medical Center, and A.R. Zaki
Masud, M.D., clinical assistant professor of
medicine.
n the shore time since their approval by che
U.S. Food and Drug Administration,
thrombolycic drugs have been hailed as a major development in efforts to reduce deaths
from heart attack. Experts project that an
estimated 150,000 Americans a year who experience a type of heart arrack known as an
acute transmural myocardial infarction are
candidates for thrombolytic therapy. When
successful, it results in reperfusion, oc reopening of che blocked corona ry artery,
potentially reducing heart-muscle damage and
saving lives. To be effective, the medications
must be administered within four to six hours
of onset of chest pain.
Klocke said corona ry arteriography has
been che 'gold standard" for assessing whether
a thrombolytic drug has worked on a patient.
Coronary arceriography muse be performed

I

SPRING 1989

��Research

23

Early Surgery Cuts Cost,
Hospital Stay in Trauma Cases
By ARTHUR PAGE
arly operative stabilization of thigh-_bone
fractures in trauma panents drasncally
cuts the length and cost of their
hospicalizacion, according to a study coor•
dinated by a UB researcher.
In the most seriously injured patients, the
study showed chat even a short delay of only
24 hours increased che average length of
hospital stay by nine days and the cost of
hospitalization by more than $13,000.
Lawrence B. Bone, M.D., assistant professor
of orthopaedic and general surgery, said the
study is rhe first prospective examination of
the benefits of early versus delayed fracture
stabilization. The results, scheduled to be
reported in the Journal of Bone and Joint
Surgery, have been presented before the
American Academy of Orthopaedic Surgery
and American Orthopaedic Association.
Bone was principal investigator for rhe
study, which involved patients at Parkland
Memorial Hospital in Dallas, where he did
his residency in orthopaedics in conjunction
with the University of Texas Southwestern
Medical Center at Dallas. He is now direc•
tor of the musculoskelecal rrauma service in
the Department of Orthopaedics at the Erie
County Medical Center.
The study compared che medical course of
parients whose rhigh-bone fractures were
stabilized operatively within the first 24 hours
after injury with that of patients whose fractured femurs were placed in traction and not
stabilized for more than 48 hours. Bone noted
that in hospitals without a trauma service the
delay in stabilizing fractures in trauma patients may stretch into days.
He said the results confirm both che experience of major trauma centers where frac-

E

BUFFALO PHYSICIAN ANO BIOMEDICAL SCIENTIST

cures in multiply-injured patients are stabilized
as soon as possible and studies based on
review of patient records from trauma centers.

B

one said che study shows chat immediate
stabilization of fractures, whether they be
of che femur, pelvis, or other bones, should
be a focus of medical efforts to treat trauma
patients.
"The patients are in the best shape they are
going to be in when they first arrive; he added. "There is very little reason nor to stabilize
rhe fracture when rhey first come in,
regardless of their ocher injuries, and that includes head injuries.
"]f a hospital doesn't have the facilities or
capabilities co do this, the patient should be
transferred to a trauma center chat does chis
routinely because it not only saves lives, but
is cost effective. By reducing the incidence of
complications, we were able to reduce
hospitalization costs by nearly half in our
study."
The study was designed co evaluate the impact of early versus late stabilization of leg
fractures on the incidence and severity of
pulmonary complications and the occurrence
of adult respiratory distress syndrome (ARDS)
in patients. A pattern of progressive
respiratory failure, the syndrome has a 50 per
cent mortality rate, according to Bone.
The 177 patients in the study were random•
ly assigned co early and delayed stabilization
groups, which were subdivided into two
groups: the less severely injured and chose
with multiple injuries. All emergent and
urgent surgical procedures were performed on
each patient according co his specific injuries.
Only the fracture of the femur was random•

ized to early or delayed treatment.
Early stabilization had a positive impact
among chose with multiple injurie s, with the
syndrome developing in only I of 45 patients
whose fractures were stabilized early, com•
pared co 5 of 37 of chose in chelate stabilization group. ARDS did not develop in any of
rhe less-severely injured patients.
Bone said significant pulmonary complications developed in 14 of the 37 patients with
multiple trauma and delayed fracture stabilization. On the ocher hand, only one of the 45
patients with multiple injuries and early fracture stabilization developed any significant
pulmonary complications.
Among the most seriously injured patients,
chose in the early stabilization group had
average hospital stays of 17.5 days at a coca!
cost of $19,492, compared to an average of
26.6 days ac $32,915 for those whose fractures
were stabilized after 48 hours.
In chose who were less severely injured, the
average time of hospitalization was 7.3 days
for the early stabilization group and 10.2 days
for chose whose fracture was stabilized after
48 hours. The cost of hospitalization averaged
$5,235 for the early group and $6,929 for the
late group.
None of the less severely injured patients
needed co be placed on a respirator or in an
intensive care unit.
Among chose with multiple injuries, 18 of
42 stabilized early and 24 of 37 stabilized late
required intubation and admission co an intensive care unit. The early group spent an
average of 2.4 days on a ventilator and 2. 7
days in the ICU, while in the lace group there
was an average 6.9 days on a ventilator and
7.6 days in an [CU.
•

SPRING 1989

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�Research

25

Exercises Promise Relief
From Arthritis in Knees

By ARTHUR PAGE
new exercise program chat has promise
to improve the mobility of millions of
Americans with arthritis of the knees
is being evaluated by researchers at UB.
In earlier studies, the researchers showed
chat Progressive Quantitative Exercise (PQE)
increased the strength of some patients' leg
muscles fivefold, dramatically improved functioning of their knees and their mobility, and
decreased pain.
Subjects were able to walk better, stand
longer, and get out of a chair more easily.
One man, an avid fisherman who previously had to pay someone to carry his day's catch
up a river bank, now boasts of being able co
scale the slope while carrying his fish.
The UB researchers, led by co-principal investigators David R. Pendergast, Ed.D., and
Glen E. Gresham, M.D., will study the effects
of PQE on leg muscles under a $501,597grant
from the National Institute on Disability and
Rehabilitation Research of the U.S. Depart•
ment of Education.
Gresham, UB professor and chair of
rehabilitation medicine, is also director of
rehabilitation medicine at the Erie County
Medical Center, where the study will be conducted .
Gresham noted that while arthritis of the
knees may occur at any age, it affects an
estimated one-third of the elderly.
When it is severe-with resultant pain, stiffness, decreased range of motion and muscle
weakness-it limits the ability to use stairs,
get up from a chair, stand comfortably and,
eventually, to walk. The UB researchers

A

BUFFALO PHYSICIAN AND BIOMEDICAL SCIENTIST

The study showed that
subjects were able to
tvalk better, stand
longer,and get out of a
chair more easily. The
exercisesincreased
strength, dramatically
improved mobility and
functioning of the knees,
and decreasedpain.
believe chat's due in large part co accompanying weakness of the quadriceps muscle that
controls extension of the knee.
The goal of PQE is to strengthen the
quadriceps muscle by gradually and precisely increasing the amount of work it is required

to perform over a three-month period. le involves isometric exercise, focusing on contracting leg muscles without moving the knee,
and isotonic exercise, which includes extension of the knee.
While their preliminary studies showed
PQE cased the symptoms and limitations, che
researchers do not believe it affects progression of the arthritis.
Subjects' progress will be monitored based
on pioneering work in quantitating muscle
strength conducted by Pendergast, UB professor of physiology, and Nadine M. Fisher,
Ed.M., UB clinical instructor of rehabilitation
medicine, who is project director.
They showed that not only is there a norm
for leg-muscle function at a given age, but
that function and strength of the quadriceps
muscle decreases dramatically past age 55.
Gresham noted chat while the work focuses
on arthritis of che knees, che researchers are
interested in "improving the rehabilitation of
people with a wide variety of musculoskeletal
impairments, particularly those affecting the
frail elderly."
Ocher UB faculty members involved in the
study are Judy Cameron-Ruh, RPT, M.S., adjunct instru cto r of physical therapy and exercise science who is physical therapy
supervisor at ECMC; Evan Calkins, M.D.,
professor of medicine and head of the UB
Division of Geriatrics/Gerontology; Beverly
Bishop, Ph.D., professor of physiology; Carl
V. Granger, M.D., professor of rehabilitation
medicine, and Theodore Papademecriou,
M.D., clinical professor of orthopaedics. •

SPRll',:G 1989

�,\ led1calSchool

26

VOWNTARY
FACULTY:
THESCHOOL'S
UNSUNG
HEROS
ou could call them the unsung heroes
of the medical school. Though they
receive no pay, voluntary faculry
generously give their time and expertise to the
medical school.
"Voluntary physicians collectively and as individuals receive far too little credit and
recognition for their contributions to medical
education and to the advances in medical
care,"said John Naughron, vice president for
clinical affairs and dean of the School of
Medicine and Biomedical Sciences at UB.
Voluntary faculty members serve on school
committees, teach courses, represent the
school in national and Stace societies, and
play an important role at affiliated hospitals .
"This information serves ro confirm that
there is a role for the voluntary physician, and
chat the school has not excluded that role,"
Naughron said. "There's a need for coexistence and involvement of a strong fulltime and voluntary staff in the years ro come
While UB still doesn't do enough co
recognize its voluntary faculty members, it is
ahead of other medical schools, the dean
noted. The long-standing Siegel Teaching
Award and the annual reception for voluntary faculty are a couple of examples.
A new award, the Robert S. Berkson, M.0.
Memorial Award in the Art of Medicine, will
be given for che second time in May. The
award goes to a voluntary faculty member
who exhibits skill in patient care and teaching
and who combines the features of scholarship
and compassion that elevate medicine in its
best sense from a science to an arc.
The award is named for Berkson, who was
a respected solo practitioner of internal
medicine and served on the voluntary faculty from 1949 until his death in 1966.
"His devotion ro patients was his greatest
attribute," said Philip Weis, M.D., clinical professor of surgery and a member of the UB
Council.
Weis met Berkson when they were
undergraduates ar UB. They continued

Y

SPRING 198'1

through the UB medical school rogether,
graduating in 1941.
"He was an excellent student and was interested in people," Wels recalls.
"The outstanding thing about Dr. Berkson
in his practice was that he was extremely, extremely devoted co his patients. He gave all
the time they required. His humanitarianism
is unsurpassed to this day. He would spend
time with the patient beyond the normal role,
and would discuss things again and again
with the family in a repetitive way that most
physicians would nor tolerate.
"He was an ardent reader and always kept
up with che newer modalities in medicine .
"Dr. Berkson liked to reach, and his
students liked and respected him because of
his concern and his abilities ."
Berkson served as a captain in the Army
Medical Corps during World War U. After his
discharge, he underwent four years of training in internal medicine, then began private
practice. He was on staff at Buffalo General
Hospital, Sisters Hospital, Millard Fillmore
Hospital, the Veterans Administration
Medical Center and the former E. J. Meyer
Hospital.
He was a fellow of che Ame rican Board of
Internal Medicine, a diplomate of the National Board of Medical Examiners, and
belonged co local and national medical
societies. He loved his community and was
active in several Jewish groups.
A family man and very devoted father,
Berkson encouraged his cwo children, Weis
noted. His son, Richard, is now a physician.
Berkson was a voluntary physician on the
staff of David K. Miller, M.0. "I admired him
and he did a good job," Miller said.
Years ago, all faculty members were voluntary, he remembers . In 1937, Miller became
the first full-time faculty member in the
medical school.
At that time there were a great number of
"service patients" who didn't have a private
physician. Times have changed and the
number of full-rime faculty continues to grow,
buc Miller hopes chat we won't see an end
co voluntary faculty.
"I think certain people have a great deal to
offer in teaching residents and interns, as well

Robert S.
Berkson,
center front,
abot ie,
enjoys the
1956 reunion with
his colleagues
from the
class of 1941.
Also pictured
at left, he is
the namesake of an
atvard for
voluntary
faculty.

as medical students," Miller said.
His personal convictions are reflected in his
actions. Miller left UB in 1974, but is now
a voluntary faculty member with the University of California.

BUFFAIO PHYSICIAN AND BIOMEDICAL SCIENTIST

�&gt;.!edical School

27

T

he first person co receive the Berkson
Award was James F.Phillips, M.D., clinical
professor of medicine.
A specialist in internal medicine with a
subspecialty in gastroencerology, Phillips
teaches students, interns, and residents at
Buffalo General Hospital and in his office.
Every year he takes a month-long teaching
service. He works with an assistant resident,
a couple of interns, and a few students for
about one and a half hours a day, five days
a week.
Sometimes a fourth-year student will spend
a month with Phillips, working at his elbow
from 7 a.m. to 9 p.m. as he makes hospital
rounds and sees patients in the office.
Every year Phillips takes on a seven-week
preceptorship, meeting with students for one
and a half hours, three times a week, to
discuss patients.
Once or twice a year, he cakes a monthlong service in gastroencerology, supervising

the training of a fellow. Phillips meets with
the fellow for an hour a few times a week.
Every day he meets with the residents and
interns who arc assigned to his patients in
Buffalo General Hospital.
Occasional! y Phillips will lecture.
All of this is time consuming work for
which Phillips receives no pay. Yee he does
it gladly. "I enjoy teaching," he said.
!e's a great way co keep up on the latest
developments in medicine, he noted.
"I learn from my students and they learn
from me," Phillips said . As modern medicine
races ahead, it's difficult co keep up with every
new advance. A student may have access co
new information in a field outside of
gastroencerology that is helpful to Phillips.
Teaching also stimulates a physician co keep
on his toes-he doesn't wane to appear uninformed to his students .
There's also a certain amount of prestige

that comes from teaching, Phillips said.
"Physicians respect someone who teaches
in the medical school," he said. "Everyone
wants to be respected among his peers, no
matter what the business.
"It's self-gratifying, I enjoy it, so I do it."
But he also feels an obligation to teach. As
outlined in the Hippocratic Oath and
elsewhere, all physicians have the responsibility co take care of the sick, to conduce research,
and to teach, he said.
The role of the voluntary faculty member
will always be here, Phillips predicted.
"More and more medicine is being practiced
outside the hospical; he explained. "Insurance
people wane it chat way, the government
wanes it that way, and magical modern
medicine allows it. People who work only in
hospitals can get a skewed viewpoint. They
see only the patients who are critically, terribly ill."
But the real world of medicine isn't filled

SPRING 1%9

BUFFAW PHYSIC IAN AND BIOMEDICAL SCIENTIST
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�Medical School
&amp; Hospital News

28

with intensive care units, he asserts. Instead,
it's marked by sore throats and belly aches
and diarrhea.
The voluntary faculty present rhe world "as
it really is,"Phillips said. "The full-rime faculry don't have rhar privilege."
A challenge facing medical education roday is how to allow students to spend more
time in "the real world" of medicine-offices
and clinics, he noted.
In his reaching, Phillips tries to inform
students about a disease and to convey rhe
things he's learned through experience. But
he also tries to be a role model and impart
the qualities of compassion, kindness,
gentleness, and friendliness. Disease doesn't
exist on its own; it's affecting a human being
and that person's family, he pointed our.
"The best way to teach people how to be
a good human being is by being a good
human being; he noted.
When Phillips accepted the Berkson Award,
he did so in rhe names of all the great teachers
who went before him, especially William Lipp,
Elmer Milch, and Clayton Green.
"I learned everything from chem," he said.
"My name is on it, but rhe award is for all
those great people who taught me my trade
and taught me rhe love of teaching."
•

SURFACE
SCIENCE
IS TOPICOF CENTER
acuity from the UB School of Medicine
and Biomedical Sciences will participate
in a new Biological Surface Science
Center established at UB. The research at the
center will focus on the interaction of
biological materials with another material at
the molecular level.
For instance, a dental implant should stay
securely in rhc jaw. However, a company making chewing gum docs not wane gum that
sticks to rhe reech. Surface science can determine why dental implants stick to gums, as
well as why chewing gum will nor stick to
reech.
The co-directors of the center are Robert
E. Baier, Ph.D., a research professor of
biophysical sciences at UB and director of rhe

F

SPRING 1989

Health-care Instruments and Devices lnsrirure
(HlDl), and Joseph A. Gardella Jr., Ph.D., an
associate professor of chemistry.
The National Science Foundation (NSF)
gave UB a $25,000 planning grant to start rhe
center. The center will be funded with annual grants of $75,000 from the NSF and
about $200,000 from HIDI, a New York Scare
Center for Advanced Technology.
Faculty from rhe School of Dental
Medicine, the Faculty of Natural Sciences and
Mathematics, and the Faculty of Engineering and Applied Sciences, are also involved
in the center.
•

STUDENTS
HONOR
ENTIRE
DEPARTMENT
he UB dental class of 1992 has
presented an award co rhe gross
anatomy faculty and staff in the School
of Medicine and Biological Sciences for their
outstanding service and dedication.
"This is che first time chat an entire class
has collectively recognized the efforts of an
entire depamnent," said Harold Brody, M.D.,
Ph.D., chairman of the Department of
Anatomy. "I chink chis award exemplifies the
sense of cohesiveness that exists between the
students (both medical and dental) and the
staff within UB's medical school."
•

T

CAPLIFTED
FOR
NON-RESIDENTS
he UB medical school has rescinded its
cap on the number of out-of-Stare applicants that can be admitted. However,
the medical school will continue to give
preference to New York Stare residents.
Ir was decided that the cap of 4 per cent
of the class, that is, five our-of-State students,
was too restrictive.
The declining pool of applicants ro medical
schools may make it necessary for UB to accept more out-of-State students, bur the cap
discouraged them from applying, it was
argued.
•

T

SISTERS
EXPANDS
HEAD,NECKPROGRAM

S

isters Hospital, in conjunction with the
UB School of Medicine and Biomedical
Sciences, is developing a "commitment
to excellence"in otolaryngology and head and
neck surgery.
The project is spearheaded by John M. Lore
Jr., M.D., chairman of the Department of
Otolaryngology and Head and Neck Surgery
at Sisters as well as professor and chairman
of the Department of Orolaryngology at UB.
Sisters has 12 years of experience in treating
cancer patients in a special unit. In addition,
UB's Department of Otolaryngology has a
fellowship in Advanced Head and Neck Oncologic Surgery, which is centered at Sisters
and the Veterans Administration Medical
Center. Established in 1979, the fellowship
is one of the first five to be developed and
is one of only 16such programs in the United
Scares and Canada.
Plans for the center include:
• Expanding facilities, equipment, and
programs.
• Expanding research and establishing a
program to develop new biomedical instruments.
• Improving medical education for professionals as well as improving educational pro•
grams for the public.
• Contributing ro and utilizing the National Cancer lnstirure's database on patient
treatment and outcomes.
• Funding the new position of Chaired Professor of Otolaryngology / Head and Neck
Surgery and filling it with a nationally
recognized head and neck oncologic surgeon.
• Developing an endowment to fund a
scientist conducting basic research.
• Developing a head and neck tumor
registry.
• Evaluating treatments, including surgery,
radiotherapy,
chemotherapy,
and irnrnunocherapy.
The University's Department of Otolaryngology will continue to work closely with che
other UB affiliates, including Roswell Park
Memorial Institute, Buffalo'sdesignated corn-

BUFFALO PHYSIC IAN AND BIOMEDICA L SC IENll sr

�Hospiwl ;-,7c.:H'S

29

BGHNURSING
HOME
ADDING
80 BEDS
uffalo General Hospital is adding 80
skilled nursing beds to one of its nursing facilities and has announced an affiliation with another nursing home.
Buffalo General's Deaconess Skilled Nursing Facility is adding a 21-bed pediatric unit,
a 21-bed unit dedicated to head trauma patients, and 38 conventional skilled nursing
beds.
The $7 million project includes renovation
and modernization of the current 162-bed
facility and is expected to be completed in
mid-1990.
The Downtown Nursing Home, an 80-bed
skilled nursing facility on Buffalo'slower West
Side, has affiliated with the General Care
Corp., parent company of the Buffalo General
Hospital.
Both nursing facilities provide services
primarily co disadvantaged persons in
Western New York. The affiliation is expected
to reduce costs for both facilities.
•

B

CATHETERIZATION
LAB
STARTED
ATMERCY

Jo hn M. Lore Jr., M .D.
prehensive cancer center. Both Sisters and
Roswell are members of the Western New
York Health Sciences Consortium.
•

NEWRULES
TOCUT
RESIDENTS'
HOURS
c looks like the recommendations of the
Bell Commission Report are becoming
reality. New Seate regulations that limit
the number of hours residents are allowed co
work are slated to go into effect July I.
Under the new rules:
• Residents may work no more than 80
hours a week when averaged over four weeks,
and no more than 24 hours in a row.
• On-duty assignments must be separated
by at least eight hours of non-working time
and residents muse get 24 consecutive hours
off each week.

I

BUFFALOPHYSICIANAND BIOMEDICALSCIENTIST

• Hospitals must enforce policies that prohibit combined
assigned hours and
moonlighting hours from exceeding the limits
on assigned hours.
Buffalo hospitals are still gearing up to meet
these requirements.
Regulations for emergency rooms went into effect in October. They include:
• Limiting assignments for residents and attending physicians to 12 consecutive hours.
• Requiring that residents be supervised 24
hours a day. This requirement can be met by
a resident in his last year of training if the
attending physician is within a reasonable
distance of the hospital, explained James P.
Nolan, chairman and professor of medicine.
The Graduate Medical-Deneal Education
Consortium is also developing a formal
system to credential residents. This would
replace the informal system of documentation
of skills chat exists now.
•

ercy Hospital is now equipped with
a Cardiac Cachcterization Laboratory, the first of its type to be constructed distinct from a cardiac surgical center
in Western New York. The lab has been fully operational since early October.
"Diagnosis and early treatment are critical
factors in preventing cardiovascular disease
from seriously afflicting chose at risk," stated
Anthony Bonner, M.D., chief, Division of
Cardiology, Department of Medicine. "A cardiac catheterization procedure is one of the
best diagnostic cools available co pinpoint the
disease state in those at risk, as well as a tool
to develop the proper regimen of treatment."
While the laboratory cost approximately
$594,000, this expense will be offset by
eliminating transportation costs and the time
spent waiting to transport patients to another
laboratory, noted Mary Ann Gottstine, assis•
cant administrator.

M

SPRING 19$9

�People

30

SPEEDING
UP THEFDA

T

homas R. Beam, Jr., M.D., associate professor of medicine and microbiology at
UB, has been named director of a new
project that will explore ways to speed up che
U.S. Food and Drug Adminisrracion's drugapproval process.
The two-year projecr also will develop
recommendations for improving the federal
agency's monicoring of drugs already on the
market for early warnings of serious adverse
reactions in patients.
The project will be conducted under a
$280,550 contract between the FDA and the
Infectious Diseases Society of America
(IDSA).
While the project will focus specifically on
antibiotics, ics recommendations are likely to
be applied co drug groups across the board,
said Beam, an expert in infectious diseases.
He is also associate chief of scaff for education and former chief of infectious disease at
Buffalo Veterans Administration Medical
Center .
He praised the IDSA for initiating the
project and the FDA for welcoming the
cooperative effort between the professional
society and federal agency.
"To their credit, they recognize that the
system is flawed," Beam added .
He said problems have been highlighted in
recent years by complaints that che FDA
drug-approval process unnecessarily delays
the approval of new drugs, some of which
already are available in othe r countries.
Critics of the process calling for reforms have
ranged from AIDS activists co officials at the
National Cancer Institute.
Despite the lengthy process designed to
assure the safety and efficacy of new drugs,
Beam noted chat some medications approved
by the FDA still have been implicated in
serious adverse reactions and patient deaths.
"The regulatory process chat now takes 10
co 12 years no longer guarantees safety; according co Beam.
"At issue is whether the compounding of
regulations benefits anyone; he added . "Ir
delays the entry of good drugs into the
marketplace, creates tremendous costs for the

SPRING IQSQ

Thoma s R. Beam , Jr., M.D.
pharmaceutical industry, is costly to the FDA
and means the Ame rican public does nor get
access r,o drugs as quickly as people in Europe,
Japan and che rest of che world."
The classic example cited to defend the
FDA's ,conse rvative approach on drug approval iis that of thalidomide, which caused
major birth defects in the children of pregnant women who used it in the late 1950sand
early 1960s. The drug was not approved for
clinical use in the U.S. when che birch defects
appeared in children born in West Germany
and Great Britain, where it was already
available.
Whil,e the layers of regulations built into
che reviiew process since then have stretched
out the drug-approval protocol in the name
of safety, Beam noced char "the recent history
of drug development has not been one of sue-

cessful protection of the American public."
He cited the examp le of benaxoporfen
(Oraflex), an anti-inflammatory drug for the
treatment of arthritis that won the FDA's
scamp of approval, yet later was associated
with serious complications and the deaths of
several patients.
Also of recent vintage, he added, were the
cases of ticrynafen (Selacryn), a diuretic
shown to be associated with irreversible liver
damage and patient deaths after it was approved for marketing, and moxalaccam (Moxam), an antibiotic that caused severe interna l
bleeding in some patients .
While the FDA subsequently ordered
benaxoprofen and ticrynafen pulled from the
market, moxalactam is still available,
although "the physician community has
essentially stopped prescribing the drug

BUFFALOPHYSICIANAND BIOMEDICALSCIENTIST

�People

31

because its toxicity outweighs its benefits; according to Beam.
He said the examples underscore the need
for a "scheme of monitoring that relatively
quickly identifies serious side effects and
brings them to the attention of the FDA so
that physicians can ultimately limit their use
of a drug or it is pulled from che marker, if
necessary."
Beam, who will work ac the federal agency
in Rockville, Md., until midsummer, was
selected from more than 30 members of the
1,600-member IDSA who applied to head the
project.
He will collaborate with FDA officials,
representatives
of che Pharmaceutical
Manufacturers Association, national leaders
in academic medicine, and approximately 50
members of the IDSA who will serve on pro•
•
jeer subcommittees.
- By Arthur Page

HEAIRSALLTHENEWS
THATKEEPS
YOUFIT
s the lights go up on the WIVB news
set, Peter Ostrow, M.0., Ph.D.,
straightens his notes and peers con•
fidently into the red-lighted camera which will
broadcast his health / medical report to
thousands of Western New York viewers.
"I used to be nervous at first; admitted
Ostrow, associate dean and professor of
pathology at UB's School of Medicine and
Biomedical Sciences. "But, a year of experience, and doing up to six hours of
research for my two-minute segment gives me
confide nce chat my report will be accurate
and informative."
Ostrow was chose n for the three-year position with WIVB over seven other hopefulssome who previously had broadcasting ex•
perience. However, with his expertise in the
field of medicine, his 14 years of experience
in medical education, and his commi tment
to UB and the surrounding area, the native
Buffalonian had some definite advantages
over the others.
"I cold the producers at the station chat my
idea was to showcase the cutting-edge medical

A

Peter Ostrow, M.D., left, confers with Jacq11ie \Valker on the news set.
research and health care that is going on at
the University and area hospitals, which is
among the nation's most advanced; explained
Ostrow. "And they loved che idea."
John Naughton, dean of the School of
Medicine and Biomedical Sciences, views
Ostrow's position as "an honor to the medical
school" which helps to create a positive relationship between the University and the
community.

W

hen Ostrow landed a seat next to anchors Bob Koop and Jacquie Walker, he
became, and still is, Buffalo's only physician•
reporter. His segments appear live on \'(,'JVB's
news broadcast ac II p.m. on Tuesdays and
Thursdays
and are rebroadcast
on
Wednesdays and Fridays ac noon.
Ostrow's topics have ranged from antibiotics and influenza, co smoking and
cancer, to medical history.
One of the biggest viewer reponses co an
Ostrow report concerned a new drug called
ciprofloxacin which helps heal hand and foot
infections in diabetics. The clinical research
which proved this drug's effectiveness was
conducted by Tom Beam, M.D., associate professor of medicine and microbiolog y, and
Jerome Schentag, Pharm.D., professor of
pharmaceutics, noted Ostrow. This is an im-

porcant development because diabetics otherwise have a difficult time fighting peripheral
circu latory infections. WIVB and Ostrow
received phone calls from Rochester, Pennsylvania, and Canada.
However, Ostrow noted char not all viewer
response has been enthusiastic.
"Once when my topic was syphilis; he
recalled, "I had mentioned in my report char
Christopher Columbus and his crew brought
the disease to the New World. The next day
the station received a phone call from an irate
viewer who happened to be the man who was
almost single-handed ly responsible for having Columbus Day declared a national holiday. He threatened to call the FCC and bring
charges against the station, but nothing more
came of it.
"I feel that if something is true, then it's
worth saying; emphasized Ostrow. "The peo•
pie at the station aren't only concerned with
ratings but with quality and integrity as well."

A

lth ough Ostrow enjoys working as a
television reporter and has learned a great
deal from the experience, his primary interests
remain in neuropathology and in medical
education. Ostrow received nine awards in
reaching excellence from his students at the
University of Texas at Houston where he was

SPRING 19$9

BUFFALOPHYSICIANAND BIOMEDICALSCIENTIST
--

-- - -~-

-- ----------

�Peot&gt;le

32

the director of neuropathology before returning to UB as an administrator in 1984.
Ost row began his academic career as an
undergraduate at UB in 1962.
"Unlike other health / medical reporters, I
am responsible for my own material because
medicine is my field of authority. My reputation as a doctor and an educator depends
upon the accuracy of what I say; Ostrow
pointed out. "I have to prepare a lesson plan
just as if I were in the classroom. I research
the topic and conduct interviews with other
medical experts. I don't just report the story-I
explain it.
"Television is a powerful medium and I see
chis job as a great opporrunity co educate and
inform the general public about recent advances in medicine."
Ostrow's uncompromising pursuit of accurate and informative topics has meant
sacrificing many early evenings at home and
saying goodnight to his three children . He
was also asked to shave his beard and
mustache, which he had worn for 18 years,
because the producers thought it was a
"sinister" and "less than trustworthy" image
for a doctor to have. His children, however,
thought just the opposite.
"My children, the oldest of whom was 15
at the time, had never seen me without a beard:
Ostrow remembered vividly. "My youngest
child, Rachel, threatened to run away from
home if I shaved my beard off. So I let her
shave it. I held a basin under my chin and
the 10-year-old first trimmed it with scissors
and finished it off with an electric razor.
"Now that my family ha s gotten used to me
without a beard, they like it better."
Although Ostrow has appeared on television for over a year, he hasn't gotten used to
basking in the limelight. He still gees embar•
rassed when he is recognized at the supermarket or at a souveni r booth at Rich
Stadium .
"I just can't get used to being recognized by
strangers; Ostrow admitted . "However, their
comments are usually very complimenta ry,
which is reassuring. le lets me know that people out there are listening to what l have to
say."
•

- By Mark Marabella

SPRING 198'1

of psychiatry at the Erie County Medical
~nre~
•

Francis J. Klo c ke, M.D. , the Albert and
Elizabeth Rekate Professor of Medicine, has
been appointed to the National Heart, Lung,
and Blood Advisory Council of the Nationa l
Institutes of Health. He is also the chief of
cardiology at UB and the Erie County
Medical Center.
•
John M. Lor e Jr ., M.D. , professor and
chairman
of the
Department
of
Otolaryngology at UB, has completed his
third edition of An Atlas of Head and Neck
Surgery.Originally published in 1962 and up•
dated in 1973,the text is considered to be one
of the most complete works relating to techniques in surgery of che head and neck. Lore
is also chairman of the Department of
Otolaryngology and Head and Neck Surgery
at Sisters Hospital
•

Gerald Sufrin , M.D. , professor and chairman of the Department of U rology, has been
appointed to the lntersociety Council for
Research of the Kidney and Urinary Tract.•

Mark Flanz enbaum , a third-year medical
student ac UB, cook first place in che medical
school's eighth annual Student Research
Forum. He won for his presentation on his
basic research on oncogenes.
Second place went to Janice Errick , a
third-year student.
In a three-way tie for third place were
Kevin Osterhoudt , a second-year student;
Gar y C ro ghan , a third-year student, and
John Klemper e r, a third-year student . •
Marvin I. Herz, M.D. , professor and chair
of the Department of Psychiatry at UB, has
been elected president of the Western New
York Psychoanalytic Society. He is director

Rohit Bak shi , a second-year student at UB's
School of Medicine and Biomedical Sciences,
received the Saul R. Korey Essay Award in
Experimental Neurology, sponsored by the
American Academy of Neurology. An
abstract of his essay, "N-Mechyl-D-Aspartate
antagonist Dexrrorphan limits dinorphin induced paralysis in racs; will be published in
the AAN annual abstract issue of the jour•
nal Neurology.
1'vo UB medical students have been elected
to positions with the American Medical Student Association . Th omas R. Piazza has
been named chapter president and Richard
S. Musialowski is recruitment coordinator.•

Mary Ann e Rokitka , Ph.D. assistant professor of physiology at UB, has been elected
vice president of the Undersea and Hyper•
baric Medical Society.
•

SPOTLIGHT
SHINES
ON ARTWORK
earring with chis issue, the Buffalo Physicianand BiomedicalScientistwill regularly
feature the artistic work of one of the
UB medical school's alumni, students, or
faculty. The work could be in painting,
photography, sculpture, poetry, fiction, or
ocher media.
If you'd like co be featured, send us a photo
of your artwork, or even a photocopy, so we
can see if it will reproduce in black and white.
Feel free to send shoes of several pieces. lf we
decide co use your work, we'll make arrangements to rake a good, clear photo .
If you submit literary work, please send a
photocopy.
We'd hate co see artwork lose or damaged,
so don't send us the original artwork .
Please include your address and phone
number, and tell us if you're a student, alumnus, alumna, or faculty member.
Address submissions to Connie Oswald
Stofko, 136Crofts Hall, University at Buffalo,
Buffalo,N.Y. 14260.
•

S

BUFFALOPHYSICIANAND BIOMEDICALSCIENTIST

�"I have been doingwacercolors
for more chan25 years. ... Many paincingshavebeeninspiredby nacureobservedduring20 )-etlTS of joggingaround
Williamsville. Paincingis a good way w sharpenyour eye, co see more
beaucyaround."

Ivan L. Bunn e ll, M.D . (M'43), Ca rdiologist, Director of the Buffalo General Hospita l Angiology Laboratory from 1960-1982

BUFFALOPHYSICIANAND BIOMEDICALSCIENTIST

SPRING 1989

�Clmsnotes

34

1960s
Edwin R. Lamm (M'60) • of
Lakeland, Fla., is president of the
medical staff of the Lakeland
Regional Medical Center and also
secretary-treasurer of the Independent Physicians Association of
Lakeland .

G eo rg e B. Kuit e (M'Z 7) • has
been disabled since 1970. His address is: lntervalc Rd., Box 1457,
North Conway, N.H. 03860.

1930s
Or van W. H ess (M '3 I ) • is
clinical professor (emeritus) of the
Yale University
School of
Medicine .
H arr y Bergman (M'3 4) •
received a gold medal in March
from Phi Lambda Kappa Medical
Fraternity for his contribution to
the advancement of medicine and
the medical sciences, and particularly for his work in the field
of urology. The Bergman's Sign,
along with a short biography of
Bergman, was included in the
27th edition of Dorland'sMedical
Diccionary.The author of several
books, Bergman is clinical professor of urology at rhe University of Miami Medical School and
New York Medical College.

Harry Bergma11 '34

founded and it is in chis spirit char
the recipient of the award is
honored .

1940s
Burton L. O lmsted (M'41) •
writes, "Enjoying retirement after
37 years in the practice of plastic
and reconsrruccive surgery in
Portland and South Portland,
Maine?'

1950s

John Ambru sko (M '3 7) • is the
namesake of the new $3 million
public health building in Manatee
County, Fla. Ambrusko is retiring after 11 years as medical executive director of the county's
health department. In addition,
Ambrusko found time for occasional stints as the physician on
cruise ships.

James E. Youker (M'S4) • will
receive the Distinguished Service
Award from the Medical College
of Wisconsin at the May commencement. Youker is professor
and chairman of rhe Department
of Radiology and is currently
serving as chairman of rhe
Residency Review Committee for
Radiology.

Maxwell Rosenblatt (M'38) •
The Maxwell Rosenblatt Commemorative Award has been
established by the Public Health
Foundation of Los Angeles Coun•
ty. It was through Rosenblatt's vision and persistence that the
Public Health Foundation was

Robert A. Bren ne r (M'59) •
gave up private practice to take a
full-time position at the Veterans
Administration Medical Center
in Syracuse.

SPRING 1%'1

Tarik E lib ol (M '62 ) • assistant
professor of medicine ar rhe UB
Schoo l of Medicine, has been
elected chief of medicine at
DeG raff Memorial Hospital.

Virgin ia V. We ldon (M'62 ) •
has been named vice president of
scientific affairs for the Monsanto Company . She will advise the
company on public policy issues
in science and medicine . Weldon
is also deputy vice chancellor for
medical affairs at the Washington
University School of Medicine in
St. Louis.
Marvin Z. Kur ia n {M'64) • has
been elected to Who's Who in
America and is a lifetime member
of Fellows' Leadership Society of
the American
College
of
Surgeons. Kurian is a clinical instructo r of surgery at UB.

David E. Pittman {M'64) • has
been invited to serve on the
editorial board of t he Journalof
Angiology.Dr. Pittman is associate
director of the Cardiovascu lar
Laboratory at Allegheny General
Hosp ital and a clinical assistant
professional of medicine at the
University of Pinsburgh School of
Medicine .
Calv in Ma rantz (M'65) •
writes from Santa Ana, Calif.,
where he is a pathologist / dermatopathologist, that he is now
serving
as co-director
of
Laboratory Coastal Communities
Hosp ital.

Virgin ia V. Weldon '62
Daniel S. Sc hubert (M'65) • of
Shake r Heights, Ohio, is currently the edito r of rhe lncernacional
Journalof Ps)'chiatryin Medicine.
August
J. D'Alessandro
{M'65) • of Newtown, Conn ., is
supervis ing psychiatrist at the
Fairfield Hills Hospital and consultant psychiat rist to the Co nnecticut Department of Mental
Retardation and Region #4 PGM
Review Committee member.
Jared C. Ba rlow {M'66) • is
president of the New York State
Soc iety of Anest hesiologists for
the 1989 ter m. Barlow is medical
di rector and chairman
of
anesthesia at Millard Fillmore
Surgery Cente r, and associate
professor of anesthesiology at UB.
John R. Fisk {M'69) • was
elected president of t he Association of Child ren's Prosthetic and
Onho t ic Clinics - a U.S. and
Canadian organization of clinic
personnel. D r. Fisk is ch ief of the
Child Amputee Clinic at the
Chicago Shrinc rs Hosp ital.

BU FFALO PHYSIC IA N AND BIO MEDI CAL SCIENTIST

�C/assnotc,

35

presented four papers at the 7th
Medical Command Radiology
Conference, both in Heidelberg,
Germany.

1970s
Jan M. Novak (M'70) • has
been elected president of th e
medical-dental staff of the Erie
County Medical Center where he
is director of the gastroenterology
division.

Mark Glassman (M'78) • was
promoted to associate professor in
the Division
of Pediat ri c
Gastroentero logy at the New
York Medical Center.

Roy M. Oswaks (M'71) • of
Virginia Beach, Va., was recertified in general surgery by the
American Board of Surgery.
Larr y Zemel (M'73) • married
Jesse Stoner in June, 1987. They
have a son, Michael, born in
April, 1988. Zemel is director of
pediatric rheumatology at Newington Children's Hospital, Newington, Conn .

Howard R. Goldstein (M'74)
• joined the Urological Professional Association in Cherry Hill,
N .)., where he lives with his wife,
Judy, and three child ren, Lee,
Lauren and Daniel.
Mic h ael L. Stei n fe ld (M'75) •
is clinical assistant professor of
cardio logy at the University of
Pittsburgh and president of the
medical staff at Forbes Health
System.
Jane K. Dorval (M'76) • was
recently appointed medical director of Moss Rehabilitation
Ho spital, a 144-bed freestanding,
not-for-profit hospital with an affiliation with Temple University's
PMR Residency Program. Dr.
Dorval is a boa rd -certified
physiarrist.

Nora 8. W ilcox (M'76) •
writes, "I have decided to make a
career of the Navy and have been
selected for promotion to the rank
of comma nd er. Also this summer
l was appo int ed head of the

Jared C. Barlow '66
Department
of
Aviation
Medicine and senior flight
surgeon at the Naval Air Station,
\'Vhidbey lsland, \Y/ash."

Cliphane W. McCleod (M'77)
• reports char he is the only
obstetrician in Hin esville, Ga.,
where he has a solo practice. His
wife, Joan, is his office manager
and nurse. The McCleods have
five children : Cliphane II, 13; Lucien, IO; twins Travis and Nice!,
7, and Natacha, 4.
Richard R. Curran (M'78) •
an internist with Buffalo Internal
Medicine Associates, P.C., has
been appointed rhe new medical
director for the Alden Medical
Center .
Angelo M. DelBalso (M'78) •
and an alumnus of the Deneal
School (72) writes chat in 1988he
presented a continuing education
cou rse sponsored by the School
of Deneal Medicine in lxcapa,
Mexico. He also presented continuing education lectures to the
89th Medical Detachment and

BUFFALOPHYSICIANAND BIOMEDICALSCIENTIST

Mark E. Brenner (M'79) •
writes, "Recently completed hand
and microsurgery fellowship in
Louisville, Ky., and am relocating
to Pinehurst, N .C. to establish a
practice in hand/orthopaedics/
microsurgery ."
Joseph Caprioli (M'79) • of
Hamden, Conn., was recently
promoted to associate professor of
ophthalmology and visual science
at Yale University School of
Medicine .
David M. Kenton (M'79) •
writes, "presently practicing cardiology in Deerfield Beach,
Fla.,-would like to hear from
Mark Brenner and Alan Schimmel." His add ress is: 5580 G
Coach House Circle, Boca Raton.
William J.Lawrence (M'79) •
is vice president of Associated
Healthcare in Buffalo.

1980s
Jain Avanindra (M'80) • is an
assistant professor of medicine
and cardiology at the University
of North Carolina at Chapel Hill.
He and his wife, Diane, have a
two-year-old son, Brian.
Jan A. Koenig (M'81) • writes,
"Completed a fellowship in joint
replacement surgery of hip and

Jan M. Novak '70
knee. Now in private orthopaedic
surgery practice in Long Island,
N .Y. Expecting first child (a boy)
March 1989."

Brett C. Shu lman (M'81) •
recently married Amy Libenson,
an attorney, of \Y/ilkes-Barre,Pa.
Shulman has a solo practice in
dermatology and dermatologic
surgery in Rochester, N.Y.
Arlene Rose Curry (M'82) • of
\Y/oodside, N .Y., writes, "\Y/illbe
married coJohn Patrick Hynes on
May 28, 1989. Unfortunately, my
father, Howard Curry, will not be
with us - he died March 7,
1988."
Richard L Collins (M'83) •
writes, "I recently accepted the
position of medical director at the
Northwest Buffalo Community
Health Center . I rook this position in October, 1988. This is a
federally funded multi-specialty
health center."

Mary M. Lee (M'83) • is a
research fellow at Massachusetts
General Hospital, Boston .
Adolph Soto (M'83) • is currencly working as a psychiatric attending at Lincoln Hospital in
the Bronx on a special bilingual/
SPRING 1989

�Classnotes

36

bicultural inpatient unit . Soto was
married on May 29, 1988.
Raymond Graber (M'84) •
writes, "l recently married che
former Mary Kowalczyk of
Amhe rst, Ohio . We hope to start
on our 10 kids soon." Graber is
director of anesthesia at che
Veterans Administration Medical
Center, Cleveland, Ohio.

M ichele Kaufman Koleszar
(M'84) • joined a women's
medical group in Bridgeport,
Conn.,
in the practice of
obstet rics and gynecology. She
marr ied Miklos P. Koleszar in
May 1988.
David J. Forster (M '85) and
Carol A. Hammer (M '85) •
were married in Buffalo in July.
Dr. Hammer is practicing
pediatrics in the Washington,
D.C. area and Dr. Forster is
associate chief resident in the
Department of Ophthalmo logy at
Georgetown University Hospital.
He will be going co USC / Estelle
Doheny Eye Center in Los
Angeles in July for a fellowship in
uveitis and ocu lar immunology.

Lesley Burton-lwinski (M'85)
• Finished a residency in June
1988 and is now a clinical instructor in che Department of Family
Medicine at the Medical College
of Georg ia.
Jon M. Wardner (M '85) • who
is a resident in P.M.&amp;R. at the
University of Michigan writes,
"Blackford Middleton (M'85)
and his wife Ursula King visited
on June 28 en rouce co Palo Alco
from Hartford . Enjoyed their
company and an evening of
gourmet beer casting. To Jim
Esse r (M'85 ), we say 'ouzo' ."

SPRING 1989

Chr istopher S. Walsh (M'85 )
• presented "Control of Neck
Disease in Carcinoma
of
Waldeyer's Ring" at the October
1988 meering of the American
Society ofTherapeuric Radiology
and Oncology. Walsh is chief resident in the Department of Radiation Medicine at Massachusercs
General Hospital.
M. Miles Braun (M'86) • has
joined the Internacional Activities
Office of AIDS Program in Atlanta, Ga .
N icholas D 'Avanzo (M'86 ) •
will be completing his pediatric
residency in 1989 and plans co
open a private pediatric practice
in Connecticut.
Donnica L. Moore (M'86) •
writes "I am well on my way
coward recovery from my spinal
fusion surgery, enjoying married
life, and love my switch from
ob/ gyn co family practice."
Jos e ph A. Pierro (M '86) • is
the first author wich Ors. Berens
and Crawford of che Clinical
Manual of Radiology,which was
released in March.

Ros ylyn R. Romanowski
(M'86) • has scarced a fellowship
in hemacology/ oncology at New
England Deaconess Hospital.
Evan D emestiha s (M'87 ) • is
assistant medical director for Sandoz Pharmaceuticals in Hanover,
N.J. He is responsible for products
in the neuro-endocrine-metabolic
cherapeu tic area including
Parlodel (bromocripcine), Sandostatin (occreocide), and Tavist
(clemanstine).

moor Psychiatric Center, Queens
Village. He began his career with
the Scace Department of Mcneal
Hygiene in 1935 ac Harlem Valley
Psychiatric Center, Wingdale.
During World War II, Haigh t
served in the Army Medical
Corps for nearly five years, seeing action in the Pacific. He rose
to the rank of lieutenant colonel.
He retired from the Army Reserve
in 1967 with the rank of colonel.

M ichele Kauf man Kole.1:.C1r'84

Brian D. Gal e (M'87 ) • has
started his residency in nuclear
medicine at Albert Einstein
Hospital, Bronx, New York.
R h onald 0. Hyndman (M '8 7)
• informs us that he is still single.
Jill E. K oe hl e r (M '87 ) • announces her marriage co Edilberco A. Mo reno, M.D. of Puerto
Rico on April 10, 1988. Dr.
Kochler is a pediatric resident at
the Hurley Medical Center in
Flint, Mich.
Thomas P. Smith Jr. (M '87) •
announces the birth of a son,
Thomas Patrick 111,born on Dec.
25, 1988. Smith has a daughter,
Megan Elizabeth, age 3.

Deaths
J. Roth ery Haight (M'3 4) •
retired director of Gowanda
Psychiatric Center, died Dec. 9.
H e was 81.
In New York Seate service for
42 years, Haight was director of
the St. Lawrence Psychiatric
Center, Ogdensburg; assistant
director of the Kings Park and
Utica psychiatric centers, and
supervising psychiatrist of Creed-

John D. Persse (M'42 ) • chief
of surgery at Mercy Hospital from
1951 through 1971, died in
Sarasota, Ra. He had joined Mercy's staff in 1948 and retired in
1981.
Buffalo-born George Hatem,
78, the doctor credited with
eradicating veneral disease, opium
addiction, prostitution, smallpox,
trachoma and filiarisis in China,
died October 2 in Beijing. He had
hoped co eliminate leprosy in that
nation by the year 2000.
He was known in China as Ma
Hai-ceh, a name chat means "virtue from overseas."
Harem received an honorary
degree from UB in September
1987 and spoke ar the medical
school's Spring Clinical Day in Ju•
ly 1986.
He is survived by his wife, two
children, a sister, and two grandchildren.
Former director of Child ren's
Hospital Mo ir P. Tanner died
August JI, 1988. He was 88.
He held the position of director for 30 years - longer than any
ocher administrator of his era.
When he retired in 1967, a
10-story addition co the hospital
was named for Tanner, who was
known as "Mr. Chi ldren's
Hospital."
He also was very active in community and religious organizations . He is survived by a son,
Duncan C., five grandchildren,
and four great-grandchildren . •

BUFFAID PHYSIC IAN AND BIO MEDICAL SC IENTIST

��Buffalo Physician &amp; Biomedical Scientist
State University of New York at Buffalo
3435 Ma in Street
Buffalo. New York 14214
Address Correction Requested

:S:on-Profi,Oll:U.S. Po,tage
PAID
Buffalo, '-.Y
Perma :So. l 11

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  <item itemId="93483" public="1" featured="0">
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                    <text>�STAFF

DearAlumniand Friendsof the school:

EXECLTnVE EDITOR
Ul's'IVERSITY PUBLICATIONS
Rob,,,,

0

T Marlen

Bl!FfALO PHYSICIA!\ EDITOR

Conni• C.1-v.-ald
Stoflo
AITTDIRECTOR
Alan

stlllln from che fine l"Jirorsh1p of Bob McGranahan to the
leadership provideJ first hy Bruce Kershner and no\\' Connie
Os,vald Stofko, every auempt has been made for its contents to
n:fleccmore fully the life of 1he total m&lt;-.:lica!Khoo] in Buffalo as
·xs·mplificdthrough its multiple constituencies, i.c::.,students, fa,;u!•
ty, alumni, parents, and affiliated huspitak The compo,ition of
the Advisory Boardwas stn:ngthenc,.I and its functions increased.
The n:wurces of the University's publications and public relations
staff h,ivc added significantly once-missing support and
participation.
I am plea5e.,Jthat these efforb have borne 1heir fruit. The
publication ll'as n."Cognizedfor its excellence when awardt.-da gold
m&lt;-dalin thi, year\ rnmpetition sponoored by the Council for Ad·
vancemem and Support of Education (CASE), This organization
1• compo5Cd of representatives from the major colleges and
universities located throughou t the United States and Canada, and
represems profel&lt;sionalsin the areas of publications, alumni rda·
tiom, puhlic n:lation~, and fund rai~ing. Of the 82 publications
,·ith whkh the Buffalo Plry~icianand Biomedical Sc1cn1is1was
evaluated, there wen: three go!J medals, three silver medals, and
chree hmn:e ml-dais awan.k,J.
Alan Kegler, the art direnor; Mrs. Stofko, anJ all of those in•
vnlved with this publication ~hould he justifhbly prouJ of this
r, &gt;gnit1vn. Thl"y have ,,mrked harJ to bring tn our s(.mstituen
•
cies a timl·ly, informati\'e puh!ication designed to reflect :111aspects
of this medical and hiomedirn! edu.:;1tional enterprise. I hope ~·ou
arc as pleased as I am about their success. I look forv,ard to their
rnmimR.J innovation~ and contributions in the years ;1head.

J. Mo(l,r

ADV ISORY BOARD
f&gt;r.John Naughton. C~ ,.,...,~
D, Harold Brody
l.!.. ~&amp;r&gt;&lt;:Y C

Dr. J..,,,.,,!-:an,.

Dr. ]Okf'h L. Kun1
1),-, CharlN l'aRandli

M,. P:aul O P:ner,on
Dr. An1rn1m~ l't,1,:n
Dt Chorln Ptu&lt;1
Dr. L.nhn- Rol,n,..,n
Dr. Thon1;10 Jl.,ocnthal
Dr. Sal... la Su,...h
Dr. Burton S1¥frn•n
Dr. S.,ph.n Spaulding
Dr. Ndson Tom
Mr. EJ,.·arJ \t', :k

Dr. Jero

Ya,~

WR ITl::RS
),.hrk Marahdla

A&lt;thur P~
Da 1d M. S, ,-Jtrma

ILLUSTRAroRS
Thomas Roonty
Jooq,h Thd

P HOTOGRA P HERS

M•rk Lrw,

la , RalinN di
- ,..on To"
B,,h \J:'abon

TE.ACHING H OSP ITALS
AN O LIA ISONS
!L,.,,·,a \',,,.,_,,,.

,1 I. /'.
f'1--~~-'

AJmini1tratim

McJ1-.,:, ..,,,,.,
Ruffalo G,,,~r:,I H,,.pu.-.l, .\t,kc Sn.n..,
Buffalo V.-,,,,,.ns AJmm1&gt;1rat1on
Modk•I C.enu,r, Joh~l'wH
Ch,lJ,en·, H,,,;pit.,I. i,.:_. D,,..,.,.,,._,,.,k,
Eue Coun,y \\«h, al C4'n1e

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....
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:1,.,,...:,,11oo1'l(.\t.C.::&gt;&lt;
S,.,- l.1n11rntt;,&gt;I

PKn,

&amp;./fa o.

TIIE BUFFALOPHYSIC!A:,./AMl

flll).

MEDICAL SCJESTIST tLN'S ". -&amp;::•
··-·· ·"" 191:P, \\,h,mc .: l, :-.:umi-...
f'yt, .,hed f,.·e t!meo ,rnn«allv, Sprn,K,

Summer, ,\.,,u,nn, l:arlv Wn&gt;t,"T,
11,J La,e
ll'1n1er . l'T1he S.hool ol McJi&lt;m&lt;"and
~ .....:!,calSc1en&lt;e,, Su!&lt; lln1&lt;·&lt;1'"1,1&lt;
of y
N..,. Yotk a&lt; Buffalo, Hl&gt; Main Srr,:c1,

Buffalo.:,i,..,
York 14214.Third cb~• bulk
""''"F~,J •t Buffa!c,,Nrw Yo,. S.-r,~
aJJ,.,.. changes 10 TIIE BUfFAlO
i'HYSICIA1'
A1'O 1110.\IEDIC.-\L

::;.c:iE:-.:nsr.
146c.F.s.AJJ"""'· HJ"

Mmr, Sm,.,.

Buffalo, Ncw York H214.

Smmdy,

--..

Jo hn N aught on , M .D .
\·
r~si.Jmt j&lt;H C/m,",! Affair,
Dean, Schoolof ~lt-dicineand
BiomedicalSciences

M,llard F,lln1or,: lfo,pna\,

R,..,,,,,~ll
P:.rk Mm"'t»l ln,t,tule, J, .
Si,,c,; H°'p,t.11, D"""" M,-C.nlr,

vcr th_ccou_rse~f the past several year~.the Buffalo Ph;11ician
and 81om,:d1cal
SciffliLJt has ,;hanged &lt;.:ons,Jerab]y.In its mm•

Dear FellowAlumni/Alumnae:

I

\\'ou!d like to wckome th, · rec, m gradu.1te to th, )\.ledical
Alumni A"5Ck.1ati,in.'fou an: . .i' ,,__: m·
. :-s &gt;IoJr group
l'J also like m extcnJ a warm and ~lnlere invita110n to 1he
new m,·mhers nf the Uni\'&lt;c'TsityRe~1Jency Program t,, bccom,
a= - :.uc· memh.--, Re:.idcm.smay join even if ihc"Yarc n,1t graJuatrs
of the L,11ven11v Jt Buffak S,·hoc: of !l.ledi im and Bio1"1ed1c:il
5' icnce
We ,ire your &lt;1rganizationand our sole purpose is 10 wrve you
,nd our medical ochool. 'i\'c- art."very im=reJ
in anything VOJ
wam to hring to our attemion for aJvice, help, or ~urpon. Be
5Url.Jthat any n,mmunication will be prompdv :onsiderl-d and
am,nJeJ to within the bt·s1 ,,four ,1hilities.
On annther note, l'-e arc gratified hy thc ,·mhusiast1, l\."&gt;,pon~
to the rail for n,,minet'S for 1he Di~tinguishcd Alumnus Award,
This emirwm graduat&lt;c'll'il! be announced anJ ho11oredin the fall.

I .·

0-

~

----;,

J o se ph L. Kunz , M .D .

�BUFFAlD

Ptoc§L~~

Vol. 23, No. 2

Summer 1989

Features

II Boonorbane?Nobody wants residents to overwork,
but will new State regulations that limit residents'
hours help or harm medical education? The debate
rages on in Buffalo.

II SpringClinicalDay.One

speaker urged physicians
to take a hand in shaping health care policy, while
another said that grapefruit pectin may lower
cholesterol. The theme of the alumni-sponsored
event was "Nutrition in the '90s."

Page32: Polio's Aftermath

Departments
Page 18: Nutrition

fl

MedicalSchool News. Lectures and conferences
covered topics ranging from microbial pathogenesis
to the question of whether we have enough doctors in this country . And UB's Match Day was better than ever.

I.DJHospitalNews.Treating the

fetus as a patient is the
focus of the new Buffalo Institute of Fetal Therapy
at Children's Hospital. Over at the Erie County
Medical Center, they're struggling with post-polio
syndrome .

Page 2 7: Match Day

IJ

People.Leon Farhi, chairman of physiology, has
been named a distinguished professor by the State
University of New York. He was honored for his
years of work in human lung gas exchange and
the human circulatory system.

Page25: Milk &amp; Sleep

IJl Research.Routine

ultrasound screening of infants
could pick up "silent" urinary problems, say UB
researchers.

ImClassnotes.Find out what your former classmates
are doing nowadays.

Cover Photo: &amp;b Walion

Page 26: Luc Montagnier

�2

Boon
or Bane?

Debate ragesover new regulationsfor residents
BY CO~"\IE

OS\\ ',\LD STOFKO

ependingon whom you talk to,
new regulations on residents'
hours and supervision are
improvingor destroyinggraduate
medical educationin the State.
They're saving or jeopardizingpatients' lives.There
will or won't be enough money and staff to
implement the changes.
One chairmansaid the potentialfor harm in his
residencyis so great, he'd rathershut down his pro­
gram than beforcedto limit hisresidentsto working
only 80 hours a week.
Another chairmansayshis
specialty is already in
compliance.
PIIOTOS

BY

BOB

\\'J\L

I O

'

�3

.· ·11
1 1·2'
·10
3.
·9

.8

l

l ~ s.

4•

6:01 a.m. Monaa1
Holx-n OriSC'OII.ll:ft.
chief surgical
residen1. s1ans his
37-hour day ai
Buffalo General
1 1osp i1al. ,\ day 111
the lif e of a
resident. as
chro ni cled in 111
ese
p ll otos. would
change under nc-w
Staw wgulations.

BUFFALOPHYSICIANAND BIOMEDICALSCIENTIST

SUMMER 1989

�ne student chose an out-ofState residency because he says
rhe regulations will damage
education, while another stayed in New
York because he says the regulations are
humanizing medicine.
The changes limit residents to working no more than an average of 80 hours
a week, with 24 consecutive hours off
each week. They also mandate increased
supervision of residents.
Other changes in the code mandate
more formal credentialing of residents'
skills and limit residents in emergency
rooms to 12-hour shifts. (See box for
derails).
The 1984 death in a New York City
teaching hospital of Libby Zion, 18,the
daughter of a well known journalistlawyer, led ro a grand jury investigation.
Though rhere were no indictments in the
case, the grand jury made several recommendations concerning emergency room
staffing, the supervision of residents, and
residents' working hours.
Then the New YorkState Department
of Health appointed an Ad Hoc Advisory Committee on Emergency Services, chaired by Bertrand M. Bell, M.D.,
a 1955 graduate of UB's medical school.
The committee recommended derailed
policies on which the new regulations are
based.
The starring dace for the regulations
on residents' hours and supervision was
ro have been July 1, but that was uncertain at press time because the Hospital
Association of New York Scace filed
litigation in State and federal courts to
have the regulations deferred.
The hospital association proposed that
if the regulations are deferred, hospitals
and medical schools should develop
policies to meet the intent of the
regulations.
.
There's vociferous disagreement on Just
about every part of the regulations, but
one thing char everybody agrees upon is
that the intent is good.
The purpose of the changes is ro improve patient care by making su~c t~at
residents don't work when they re improperly supervised or sleep-deprived.
The changes also try to regain a balance
between education and service residents are employed by hospitals, but
they're there to learn.

0

4

SUMMER 1%9

A second point of agreement is that
the regulations present a number of
hurdles. It means a rethinking of the
educational system.
"We'renot saying it's going to be a piece
of cake; conceded a spokesman for the
State Department of Health.

W

cent are we interfering with the educational process and how do we plan co
compenate?"
In surgery, the regulations are interfering to a great extent and there's no way
around it, shore of shuning down the
residency program, according to Lewis
M. Flint, M.D., professor and chairman
of surgery ac UB. If the surgery program
is forced to obey the letter of the law, it
will damage surgical education so much
that it would be better to stop training
surgical residents.
"I'm quire sincere about ir; he said.
Ocher specialties have been able to
meet the regulations by reducing the
number of patients they see, Flint said.
But each surgical resident must perform
a minimum of 600 surgeries with in 55
months of training co meet national standards, and UB e..xpectsresidents to perform 800 surgeries.
Flint complai ned that the figure of 80
hours a week was chosen almost at random. He doesn't see how residents can
work less than 96 hours a week.
The program trains residents co act like
surgeons, he explained. A surgeon cares
for the patient before, during, and after
an operation.
"Ifa resident operates on a patient, the
resident is given as much responsibility
for care of the patient as he's capable of
shou ldering; Flint said . That includes
staying with a patient whds having tro~ble, no matter how many hours the resident has already worked.
"If we asked a resident to leave at the
end of his shift, he would say 'no; no
matter what the health department said;
Flint asserted. "They like taking care of
their patients and they rake their obligations co patient care very serious ly."

hile several other states are
examining these conce rns, New
York is the first to impose new regulations. Many people question whether
these regulations, as written, are the best
way to meet these lofty intentions.
"Are we improving services co patients?
Arc we improving education?" asked
Michael F. Noe, clinical associate professor of social and preventive medicine.
"There arc a lot of suppositions here that
haven't been tested. I'm not sure we have
rhc answers co chose questions .
"If you decrease the number of hours
of experience in the clinical arena by re•
quiring residents to work an a~e:3ge_of
80 hours a week, arc you depriving individuals of a certain number of
decision-making experiences that are
crucial? Will you have to increase the
length of training? That question is
unanswered; stated Noe, who is also
chai rman of the coordinating board and
the administrative commince of che
Graduate Medical-Dental Education
Consortium as well as vice president of
he problem could be solved by adding
professional affairs at Buffalo General
a year co the residency program.
Hospital.
"There are 100 good reasons for
"The fact of the matter is, patient care
lengthening
the training program, but
is a critically important clement in
that's
nor
one
of them; Flint said. "A betgraduate education. By decreasing the
ter alternative would be to close the pronumber of experiences, you're abgram."
breviating the educational process.
He criticized the health department for
"I'm certain ly not advocating that peomaking wholesale changes in the educaple work in a sleep-deprived state, or that
tional system without any evidence chat
we should put people through an exrhe changes will work.
perience
chat is physically
or
Referring to the death of Libby Zion,
psychologically harmful. Bue to what exFlint said, "The incident that precipitated

t

BLIFFALO PHYSICIA!s AND BIOMEDICAL SCIENTIST

�1v

~

c-1I',--

5

'-

this hysteria - and that's what it is,
hysteria - happened on an internal
medicine teach ing service.
"It can't happen on a university surgical
teaching service. A jun ior resident is not
left alone to make a life-and-death decision ."
Junio r residents are supervised by
senior residents, who have usually been
out of medical school for six years that's longer than some residency programs in other specialties.
A major operation is almost never performed without the attending physician
in the building, Flint added.
There's no data stating chat residents
are making poo r judgements because of
sleep deprivation, he said . The only data
t hat exists says that surgeons get
grumpy after being up for 36 hours .
Flint expects that the new regulations
will be modified .
"If they're not, then we're going to have
a lot of trouble in surgery; he said .
At the othe r end of the spectrum is
family medicine, wh ich is already in comp liance with all aspects of the
regulations.
The maximum workweek for family

BUFFALO PHYSIClAN AND BIOMEDICAL SCIENTIST

6:30 a.m . Mo n day
Oppos ite page.
s urgica l reside rns
discuss cases
befo re rou nds. 6:44
a.m. Monday
Above. Drisco ll
sees pa licni s ,n
irnc nsive care.
7: 17 a .m. Monday
1..
ef 1. studc rns and
rcside rns go 10 a
m ee1ing.
10.2 1 a.m. Mo nday
Bonom lef1. Drisco ll
prepa res fo r
surgery.

medicine residents is 75 hours, noted
Thomas C. Rosentha l, M.D., director of
the family medicine residency at UB and
clinical associate professor . For years
family medicine has used a system of
supervision
that meets the new
requirements.
"The faculty is active in patient practice," said Rosenthal, who is also director of the Office of Rural Health. "We
utilize, but don't rely, on residents for
care."
Family medicine is an outpatient
specialty, Rosenthal noted . Forty per cent

SUMMER 19S9

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•

of residents' time is spent in outpatient
care.
Ocher specialties fall somewhere between surgery and family medicine.
For instance, overall, residents in
gynecology and obstetrics work 80 hours
a week, but "overall" is the key word,
noted Myroslaw M. Hreshchyshyn,
M.D., professor and chairman
of
gynecology and obstetrics at UB.
At Children's, which is UB's main and busy - obstetrical site, a resident
works in labor and delivery the entire
time he is on call. At ECMC, che resi-

llLFFAIO PHY~IUAN AND BIOMEDICAL SCIENTIST

�dent works in gynecology and may have
to attend patients in the emergency room
or occasionally perform emerge ncy
surgery at night . Otherwise, he can sleep.
During a rotation at Children's, a resident may average 90 or 100 hou rs a
week, but at ECMC, average only 65 or
70, Hreshchyshyn said.
The regulations force the program to
distribute work more equally, but
Hreshchyshyn doesn't anticipate a
problem.
He sees more difficulty with the supervision requi rement. The program has

BUFFALOPHYSICIAN AND BIOMEDICAL SCIENTIST

been working toward providing better
supervision for residents already, but che
law makes it inflexible and costly, he
said.
Five years ago, full-rime faculty
members started caking turns spending
one or two nights a week at Child ren's
Hospital co supervise residents - free of
charge.
"I sold them on the idea because it was
good practice, it was good for the patient,
and it was good for the resident,"
Hreshchyshyn said. Little by little he was
introducing the idea to each hospital.
About a year and a half ago, full-rime
and volunteer faculty members at Buffalo General Hospital started spending
nights at the hospital. Bur because it was
prompted in part by a shortage of
residents, the faculty members asked co
be paid, Hreshchyshyn noted.
Since the supervision at UB's hospitals
is being mandated, rather chan performed by faculty of their own volition
they too will want to be paid:
Hreshchyshyn predicted .
Ultimately, his department will find
ways to adjust within constraints of the
law, he added .

Flexibleor inflexible?

t

he inflexibility of the regulations is
the big drawback, agreed Gerald
Logue, M.D., chief of staff at the Buffalo

Veterans Administ ration Medica l Ce nter. He is professor of medicine and head
of the Division of Hemato logy in the
Department of Medicine at UB.
"The point needed to be made that
the re should be a ba lance between
education and service , but the point is
being made with a nuclear weapon,"
Logue said. "There are ocher ways co
make sure residents are awake and alert
chat still allow you educational opportunities .
"If these regulations were less driven by
hours, it would be better . The hou r thing
limits your flexibility."
Because che regulations are so rigid,
the continuity of care is disrupted, Logue
said.
Residents can be on call any night of
the week, buc outpatient clinics are
scheduled only on certain days. If a resident works at night, he has to miss the
clinic the next day. Yeea very important
need in medical education is co have
residents see more ambulatory patients .
And residents teach medical students.
If the residents aren't around , the education of the students will suffer, Logue
said.
Because of the invasiveness and intrusiveness of governmental regulations,
New York State is the worst place in che
country co practice medicine, Logue
complai ned .
"The regulatory climate is going co
drive good people out of New York
Stace; he said.
Vicki Zeldin, a spokespe rson for the
health department, countered chat che
regulations are indeed flexible.
The rules say chat residents shouldn't
work more than an average of 80 hours
a week, she pointed out . Some weeks
they can work more.
"We're not going to be there scopwacch
in hand," Zeldin said.
"The bottom line is, if someone is coo
tired co serve patients adequately, chat
patient's life is in jeopardy ." She said chat
the position of David Axelrod, M.D., the
Scace commissioner of health, is chat "if
these regulations didn't go into effect, patients would die. They're very important
to the quality of care.
"Personally," Zeldin said, "if 1 had the
choice between being treated by the
same doctor who had been up for hours

SUMMER 1989

7

�8

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8.20 /l Ill. Monda_, .
Driscoll. top lctt.
explains 10 a patien t
the de tmc1emen1 he'll
perform w11I) caruana
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Top ngh1. DriS&lt;"0II
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l.&gt;illient 10 surgery
9 pill

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Lower left. surgery
conunues un11I
10:so p.m.
.\lidnig/11
At lower right. DriS&lt;"oll
discusses a case wilh
01her residents .

so I could have continuity of care, or getting a fresh doctor, I'd choose a fresh doctor."
Residents rend to resent patients near
the end of an exhausting 36-hour-day,
she added, and these regulations are
necessary to remove some of chat
resentment.
"Frankly, these are new regulations,"

SUMMER 1989

Zeldin said. "If we find that physicians
all over the State are saying that they
can't spend enough rime with patients,
we would listen."
Nobody is ever comfortable with
changing from the familiar way of doing
things, she pointed out, and that may account for some of the concerns people
are expressing.
Residents themselves view the regulations as benign, said James Woytash,
D.D.S., M.D., chairman of the House
Scaff Committee of the Graduate
Medical-Dental Education Consortium.
The new regulations "provide the best of
both worlds.
"They give residents time to spend with
patients, and they give them time to keep
up with the medical literature and have
time for a personal life,"said Woycash, a
fourth-year resident in pathology at the
Erie County Medical Center. "It looks
very promising."
Residents in some specialties, especially
surgery, are worried about seeing their
cases through to completion, he said.

They're also concerned that if there's nor
enough money to hire all of the needed
ancillary staff, patient care will suffer.
While residents weren't demanding the
changes, no one has left UB because of
them.
"The doomsday prophets were saying
it was going to drive people away from
New York State in all areas of medicine,"
said Woytash. But looking at the latest
Match Day results, "the great exodus out
of New York Seate hasn't occurred:'
For UB medical students, the percentages of people choosing to stay in New
York State are about the same as in
previous years. From 1985 to 1988, between 56 per cent and 66 per cent of the
class stayed in New York. This year, 62
per cent stayed .
Anecdotal information from fourthyear medical students at UB, however,
indicates mixed feelings about the regulations. John Osborn feels that the regulations will damage the training program
in New York, so he accepted a pediatric
residency
at the University
of

BUFFALOPHYSICIANAND BIOMEDICALSCIENTIST

�Washington in Seaccle.
Classmate Doug Sillarc, on che ocher
hand, says che regulations are "making
medicine more human ." He chose a
residency in internal medicine ac Millard
Fillmore Hospital in Buffalo.
Ocher students were confident that, no
matter what specialty they chose, the
regulations will have no effect on them.
"l doubt it's going to affect surgeons;
said Joseph Ciac ci, who accepted a
surgery residency at Mt . Sinai in New
York City . "It wasn't designed around
surgery residents. The system for surgery
is okay as it is. I really think I'll be working just as hard as residents did in the
past."
Some students who chose out-of-Scace
residencies noted char those states are
looking at similar regulations, but they
aren't expected co be as drastic as New
York's.

9

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Is it practical?

e

ven if you agree that we shouldimplement these new regulations,
many people ask, "can we implement
them?" The two biggest concerns are
whether there will be enough money and
staff.
"We believe that the changes to the
code carry a very important message;
said Thomas J. Faith, assistant administrator ac the Erie County Medica l
Center. "They establish a daily menu for
che quality of care. I believe that with all
my heart .
"But being able to do it is another matter."
But when push comes to shove,
ECMC won't cut back on services, he
emphasized.
The hospital administrators interviewed agreed that, somehow, they will
comp ly with the changes. Bue it won't be
easy.
"Down the line it might be bette r, but
the transition will be wicked; noted
Marcia A. Brierly, administrative director in the Department of Medical Education at Millard Fillmore Hospital.
The health department says that funding for the changes is available, though
the hospitals wonder .
Private hospitals, and even the Erie
County Medical Center, get most of
their funding through third-party payers
BUFFA ID PHYSICIA N A ND BIO MEDICAL SCIENTIST

,.

Illa..:
SUMMER 1989

��(such as private insurance companies or
the Stace's Medicaid program). The State
regulates the rates that hospitals can
charge third-parry payers.
In July, the rates are being increased
and the hospitals in the State will receive
an extra $270 million to cover the coses
of the changes, said Zeldin of the health
department.
Since an outside consultant had
estimated the changes would cost between $200 million and $300 million,
chat amount is in the ball park, she
noted.
Bue since the regulations are so new
and haven't been implemented yet,
"there's a concern as to whether anyone
knows what the financial impact will be,"
countered Brierly of Millard Fillmore.
"It's difficult co know whether chis will
cover everything."
Finan cially, the Batavia and Buffalo
Veterans Administration
Medical
Centers operate a bit differently from the
ocher teaching hospitals. Their funding
comes from the federal Veterans Administration, noted Logue.
So far, the VA hasn't promised any
new money for its hospitals in New York
State co meet the code changes, but
Logue predicted chat the federal agency
may allocate extra funds as other states
adopt similar regulations.
In the meantime, the Buffalo VA
Medical Center will spread its resources
more thinly.
"It'll be macaroni and cheese instead of
steak," said Logue.
Cutting back on che number of hours
a resident can work is creating a manpower shortage, hospital representatives
agree.
"The bottom line is there'll be less work
done by residents, so there has co be
some other way co take care of patients,"
said Logue.
Hospitals are adding more staff, with
nurse practitioners and physician's
assistants most in demand. Bue since the
regulations have created a new demand,
they've become hard co recruit, noted
Logue.

t

he health department's position is
that it may be difficult, but it's doable.
"Our belief is that, except for isolated
incidents, hospitals will be able co find

BUFFALOPHYSICIAN AND BIOMEDICALSCIENTIST

II

I

the staff; said Zeldin. "They should be
able co find the ancillary staff and use
attendiings without having to hire a lot
of extra people. We're not saying it's going to be a piece of cake."
The health department isn't going to
be counting heads on Day One of these
regulations; it just expects a good-faith
effort from the hospitals, she said .
Hospitals are also looking at adding
more registered nurses, phlebotomists, IV
teams, and transport people.
Logue said that the cost for additional
staff at the Buffalo VA Medical Center
is approaching half a million dollars. Bue
he conceded that it's hard to sort out
which changes are being made simply co
meet these new regulations.

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SUMMER 1969

�12

"We probably would have had to add
an IV team anyway," Logue pointed out.
"There was too much service and not
eno ugh education going on. If these
regulations
hadn't
come a long,
something else would have forced us co
do this."
To meet the staffing crunch, hospitals
would like co hire more residents. Bur the
number of residents a hospital may hire
is limited by the accrediting bodies, explained M. Luther Musselman, M.O.,
director of medical education for Millard
Fillmore Hospital and clinica l associate
professor of medicine. Besides, it would
be expensive and difficult to find enough
qualified residents to fill some slots.
One hospital chat is adding more
residents chis summe r is Sisters Hospital.
Five new residents from osteopathic
schools will start in a program that was
begun independently of the health code
changes, said A. Charles Massaro, M.O.,
vice president for medical affairs at
Sisters and clinica l assistant professor in
medicine and family medicine at UB.
Fortunately, the timing is convenient.
Sisters also plans to spread hours a bit
more evenly between junior and senior
residents. Normally, as a resident advances, he spends less and less time on
call, Massaro explained.
"But (senior residents) are going to
have to, much to their chagrin, work
more on call; he said. "It was a nice little perk they had, but we can't do it any
more. I don't blame them for not liking
. "
It.
While hiring ancillary staff is the
hospitals' main strategy, it's only a stopgap measure because "it only helps solve
the problem with hours; it doesn't solve
the supervision prob lem; said Brierly of
Millard Fillmore.
In the past, attending physicians or the
patient's doctor were on call and could
be reached by phone if a resident had
questions at night. The supervising
physicians had to be able to get to the
hospital within 20 or 30 minutes.
Now, supervising physicians in seven
acute care areas - internal medicine,
family practice, surgery, anesthesiology,
obstetrics, psychiatry, and pediatrics must be at the hospital 24 hours a day.
A resident who has completed four
years, or is in his last year, of his residenSUMMER 1989

BUFFALOPHYSICIANAND BIOMEDICALSCIENTIST

�13

cy may supervise ocher residents.
To solve chis problem, hospitals have
several choices:
• Require fellows in subspeciaky training to work at night.
• Use senior residents to supervise
ocher residents.
• Hire attending physicians and pay
them per hour to stay in the hospital at
night.
• Require
full-time
faculty
to
periodically spend a night in the
hospital.
Each of these solutions has its
drawbacks.
Fellows in subspecialty training won't
be attracted to the idea of overnight
shifts and it may interfere with their
education, said Noe.
The problem with hiring senior
residents is that there are few of them
and, like all residents, they're limited to
working no more than 80 hours a week.
When it comes to hiring attending
physicians, money and availability are
the two big drawbacks.
BUFFAID PHYSICIAN AND BIOMEDICALSCIENTIST

"Physicians are just not out there to
hire," said Faith of ECMC. And even if
you can find them, you have to be able
to pay chem competitive wages.

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Noe estimates chat it would cost at
least $350,000 to $400,000 a year to provide 24-hour coverage in one specialty in
a single hospital.
And what happens to the attending
physician who takes care of his practice
all day, supervises at the hospital all
night, and sees his private patients again
the next day? asked Brierly of Millard
Fillmore.
Another twist to this dilemma is that
making night shift work lucrative in
order to make it appealing to physicians
could work too well. Some doctors may
decide to work only nights, she said.
Musselman added that with so many
of these night positions opening, we may
run into a shortage of physicians in the
nexc few years .
"We'recreating a monster in a different
area," Mu sselman predicted.

lxgins.

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nocher option is to require UB faculty members to stay overnight in
the hospital.
"Historically, the residency training experience was chis opportunity to have as
intense and as emergent training in patient care as possible," explained John
Naughton, UB's vice president for
clinical affairs and dean of the medical
school. "Residents providing coverage in
hospitals around the clock goes back to
the cum of the century. The supervising
physician can usually go home at night,
permitting the resident co fill the gap."
Bue that is changing and will be extremely difficult for physicians living in large
SUMMER 1&lt;189

�I

urban areas such as New York City.
Each medical director, with each director of service, is working out what faculty
14 doctors have to be at the hospital overnight, the dean said. The department
faculty are involved in the decision.
Bue the definition of who may be a
supervisor poses a problem, Noe pointed
our. Supervisors in certain areas must be
board-certified or board-admissible physicians. Bur there are fully qualified physicians who may have chosen co skip the

adding char the question may end up being settled in court .
If the attending is held responsible for
any mistake a resident makes, attendings
may view the supervision of residents as
a high-risk enterprise they'd rather avoid,
predicted Faith of ECMC. Eventually,
there might not be enough attendings to
supervise residents and the number of
people in graduate education could
decline.
Noe also questioned whether teaching
hospitals are being asked to meet a
higher standa rd than community
hospitals char aren't required to have a
full array of specialists on site.
"Presumably, the management of patient care at those hospitals can be provided by somebody who can be called
from home," he said. ''.A.rewe defining a
different, higher level of patient care in
teaching hospitals than in other community hospitals?"

Otherregulations

a

certification test and, because a certain
time period has elapsed, are no longer
eligible to become board certified.
"So does a program director have to
make a distinction between his faculty?"
Noe asked. "It's causing some uncertainty among program directors."
Conversely, he pointed out, a physician who is board certified and, by
definition, is qualified to supervise
residents, may be a subspecialist who
finds it difficult to supervise a broad
array of problems.
Still another problem with on-site
supervision of residents is the question
of liability of the supervising physician.
Can one attending physician be available
to perhaps 5 to 10 residents, each of
whom is responsible for IOto 20 patients?
"Can the attending physician carry
that responsibility and meet the intent
of the standard? It's uncertain; Noe said,

norher portion of the code called
for more formal credentialing of
residents' skills and for limitations on
residents' hours in the emergency room .
Generally, those have been easier to
meet.
For UB, it was a challenge to invent
a system that could be shared by its nine
different reaching hospitals.
A task force of the Graduate MedicalDental Education Consortium, headed
by James M. Hassett, Jr., M.D., associate
professor of surgery, set up the system.
He is also assistant professor of
biophysics and anesthesiology .
Before the changes, when a supervising physician deemed a resident had
shown he was able to perform a procedure satisfactorily, the supervisor gave
the resident permission to perform the
procedure on his own .
The documentation wasn't structured
and there wasn't communication between the hospitals.
Now the faculty in each specialty have
defined uniform criteria char residents
must meet before they're allowed co do
a procedure on their own. A computer
is used to record the number and types
of procedures residents do under
supervision.

Looking at a resident' s record, the
chairman decides whether to grant
privileges to the resident. When residents
move between hospitals, their records
move with them.
While chis is probably rhe easiest and
cheapest of all of the code changes, administrators at Millard Fillmore Hospital
noted chat the start-up costs alone at
their hospital ran $45,000 .
Still another change in the code, in
place since October, requires that
residents and attending physicians in
emergency rooms be scheduled for no
more than 12 consecutive hours. The atrendings in rhe emergency room can't be
the same ones cover ing the rest of the
hospital.
Again, cost and manpower are the
issues. Faith of ECMC estimates that it
will cost about $1 million a year just for
physician coverage at his hospital.
Rural hospitals probably have the
toughest time recruiting physicians, bm
city hospitals are scrambling, too.
"We're recruiting nationally to staff our
emergency rooms and we're just making
it," said Musselman of Millard Fillmore,
though his hospital was one of several
Buffalo hospitals chat had mer the
regulations before they went into effect.
Noe pointed out that the medical
school is planning to establish a residency training program in emergency
medicine for 30 residents .
"As the program develops it will go a
long way to relieve the manpower problems, particularly upstate," he said. Also
easing the problem is the fact that people in internal and family medicine are
showing more interest in emergency
medicine.
"I don't think there's any doubt that
(the changes to the code) are burdensome," said Naughton. "It's seen as adversaria l rather than as a positive thing.
"Bur for us as a medical school, the
changes create an awareness that we
need to do a better job of supervising our
srudents and residents and of credentia ling them. It makes good pedagogical
sense.
"Sometimes we don't solve a problem
without a crisis. In the short haul, it may
be tough. But in the long haul, we
•
should be able to do it."

BUFFALOPHYSICIANAND BIOMEDICALSCIENTIST

�SUMMARY
HOURS
Effecnw:JwlyI, /989
• Residents may be scheduled for
no more than 80 hours a week,
when averaged over four weeks.
• They may be scheduled for no
more than 24 hours in a row.
• On-duty assignments must be
separated by at least eight hours of
non-working time.
• Residents must get 24 consecutive hours off each week.
• Hospitals must enforce policies
that prohibit combined assigned
hours and moonlighting hours from
exceeding the limits on assigned
hours.
• In certain departments that
don't have a high volume of acutely
ill patients and where the resident
is able to get enough rest, there JS
more flexibility in scheduling. (Ex
eluded from this clause are anesthesiology, family practice, medical,
surgical, obstetrica l, or pediatric
services.)

...
•,i
t',·

/10

:9
·.8

lil.

2·
3:

-,

4.-

.7 .? _s•.
s p.m . Tuesday
Opposite page.
finishing surgery
6:50 p.m . Tuesday
TOp. Driscoll
confers with or . M.
carlin and Dave
1tarshman. a
surgical resident.
6:57 p.m . Tuesday
center. Driscoll
examines a patient.
7:05 p .m . Tuesday
Driscoll and
photograph er BOb
Walion end their
workday .

ON-SmSUPERVISION
Eff«aw:1111,
1 989
• A sufficientnumber of supervising physicians must be present tn
the hospital 24 hours a day m the
acute care specialties of anesthesiology, family practice, mediane,
obstetrics, pediatrics, psychiatr¥
and surgery.
• Supervising physicians mustbe.
board certified or board adm1ss1ble,
or have completed a minimum oJ
four years of postgraduate tramingi
• The supervising physician may
be a resident in his final year ofpost
graduate training if the padeJj
physician can get to the hosp
within 20 to 30 minutes of beliDRP
called.

CREDENTIALING
E/f«tiwJan.1

1989

• The medical staff must
written documentation o
care privileges granted to

EMERGENCY
ROOM
Eff«tiw
• Residents and attending ph
cians can be scheduled for no mote
than 12 consecutive hours.

SUMMER 1989

15

�I

16

Samuel 0 . Thi e r

�Spring Clinical Day

17

Doctorsurged to shape national policies

l

1

l
BY CONNlE OSWALD SlDFKO

=

~

f physicians don't take
a hand in shaping this
::::
country's health care
:::
policy, they're shirking
their responsibilities,
according co Samuel
_.._-_
~ 0. Thier, M.D., president of the Institute of Medicine of the
Nationa l Academy of Sciences .
Physicians should be key players in
deciding today's tough health care issues,
but "the silence from the medical community is deafening," said Thier, who
gave the annua l Stockton Kimball
Memorial Lecture at chis year's Spring
Clinical Day on May 6.
The United States leads rhe world, but
we're at a point of instability, said Thier,
who is also visiting professor of medicine
ac che Johns Hopkins University School
of Medicine and clinical professor of
medicine ac the George Washington
University School of Medicine.
It's rime to choose whether we will
evolve and remain leaders, or give up
chat leadership to some ocher group .
Ideas for evolution are desperately needed and they have to bubble up from the
medical community.
"I don't see a sense chat we're engaging the issue," Thie r said. "What will
replace chis? We have the responsibility
co chink about what we want next."
The policy makers in Washington view
the medical community "as apologisesfor
the status quo" rather than an active

-

BUFFALO PHYSICIAN AND BIOMEDICAL SCIENTIST

Physiciansshould be
key players in deciding
today'stough health
careissues,but "the
silencefrom the
medicalcommunity is
deafening,'' said
Samuel 0 . Thier, M.D.
of the National
Academy of Sciences.

force for change, Thier noted.
One of the issues facing physicians today is access co care. There are 35 to 40
million people in this country with no
hea lth insurance at least pare of the year.
One to two million are turned away from
care, and the rest don't seek care as often.

When Thier was a resident at Massachusetts General, physicians who wanted
hospital privileges had to contribute time
to care for the indigent . Now, some
physicians feel that if they're not reimbursed for care, they don't have to provide it.
"I believe chat's an abrogation of our
social contract," Thier said.
Some social problems, such as teenage
pregnancy, the indigent, and aging, aren't
dealt with adequately because physicians
cry co force the issues into a medical
model, T hier said.
Picture the elderly person who lives in
poor housing: he or she becomes depressed, doesn't eat much, and gees
pneumonia . The physician successfully treats the pneumonia and sends the
person back to the same house.
Rather than just treat the pneumonia,
we need co keep people functional, Thier
pointed out. He noted that in Japan,
they tail off the money they spend for
medical care for the elderly and spend
it instead on housing and fo.od.
In this country, we need to create some
kind of a plan chat uses preventive
strategies and somehow moves from a
medical model to a social model, he indicated . We made a mistake 50 or 60
years ago when we separated schools of
medicine from schools of public health.
"If we simply watch the scene evolve,
we won't have met our professional
responsibilities," he concluded.
•
SUMMER 1989

�Spring Clinical Day

18

PECTIN

It thickens jelly, but can it thin arteries?

�Spring Clinical Day

19

WR:R:T

TJE N

JBY

CON

][JE

((})§W

A JLD

§TO&gt;FKO

utrition in the '90s" was the theme of the 52nd annual
Spring Clinical Day, held May 6. The event, which also

)

included the class reunions, was sponsored by the UB

)

Medical Alumni Association.
The topics of the scientific sessions were nutritional
of cholesterol; epidemiology of nutrition

management

and cancer; recent advances

in characterizing and managing obesity; new fuels for the gut, and
normal nutritional

requirements.

CHOLESTEROL
I

II

chink we can lower plasma cholesterol and LDL (which is connec ted
to an increased risk of heart disease) with _ , .,..v.,a
grapefruit pectin and no change in diet,"
said James J. Cerda, M.D., professor and
associate chairman of the Department of 1 , ,I"' 0 •
Medicine at the University of Florida at(: ~
Gainesville .
According to studies performed by
Cerda and his colleagues, grapefruit pectin appears to lower cholesterol. (Pectin ,
is a water-soluble fiber that binds adjacent cell walls in plants . It's used by
homemakers in preparing jellies and
jams .)
will actually reduce atherosclerosis once
In experiments with pigs, Cerda found
it forms. That's an important question
that even when fed a high-fat diet, the
because
most of us already have atheropigs' cholesterol decreased when they
sclerosis,
Cerda reminded his audience.
were also fed pectin . The pectin also apThe
researchers
also conducted a
peared to prevent atherosclerosis, the
double-blind
trial
of
people with high
plaque buildup that results in narrowing
cholestero
l
who
couldn't
or wouldn't
of the arteries.
change
their
lifestyles.
He
noted
that it
The next question the researchers
wasn't
hard
to
find
subjects.
would like to look at is whether pectin

r.

)
)

][JLJLU§TRAT][O)
BUFFALOPHYSIC IAN AND BIO MEDICAL SCIENTIST

BY

The researchers found that pectin was
,statistically significant in reducing
·cholesterol. One-third of the subjects
had at least a 10 per cent decrease in
cho lesterol while taking pectin.
Cerda emphasized chat he's not suggesting that people rely only on pectin
to lower their cholesterol. They should
also eat a good diet and get exercise.
Since it's important for physicians to
advise patients about diet, medical
schools shou ld prepare them by teaching
nutrition as part of the curriculum,
Cerda added, and physicians should also
rely on dieticians more than they do.

CANCER

W

hen it comes to reducing the risk
of cancer, fiber - but not just any
fiber - may be beneficial, according to
Saxon Graham, Ph.D., professor and
chairman of Social and Preventive Medicine at UB.
Vegetable fiber, but not fiber from
grains, is helpful in reducing the risk of

Jr({))§JEJP&gt;H

THIEJL
SUMMER 1989

�Spring Clinical Day

I zo

rectal cancer, according to a study by Jo
Freudenheim, assistant professor in
Social and Preventive Medicine at UB.
Graham pointed out that that's not the
fiber the National Cancer Institute cold
us to eat.
Vitamin A may reduce the incidence
of cancer of the mouth, larynx, esophagus, bladder, lung, and cervix, he said.
As well as searching for foods char prevent cancer, researchers are also on the
lookout for ones chat cause cancer.
There's epidemiological evidence eying
the amount of far in one's diet co both
colorecral and breast cancer, Graham
said, but he cautioned that it's a leap in
logic to say fats cause chose cancers.
He also observed chat closely associated with fats are obesity and the coral
calories ingested. These interrelated factors could be connected co cancer of the
colon and rectum. And since physical exercise can reduce obesity, exercise may
also be associated with decreased risk.
Ir is also possible chat exercise by itself
may reduce the risk of colon and breast
cancer.
While the ocher recent, well-publicized
recommendations of the National Research Council seem well-founded,
there's little epidemiological evidence to
support its advice co decrease the protein

SUMMER 1989

in our diets or to increase grains or
calcium, Graham said.

The first strategyin
dealing with obesity
should be prevention.
Physiciansshould
recognizethe family at
risk - whereone or both
parents are obese.

OBESITY

T

he first strategy in dea ling with obesity should be prevention, said Lyn J.
Howard, B.M., B.Ch., ER.C.P., head of
the Division of Clinical Nutrition at
Albany Medical College.

Physicians should recognize the family
at risk - where one or both parents are
obese, said Howard, who is also a professor of medicine and associate professor
of pediatrics. Children shouldn't cross
over their growth curves, even if the
children are at the correct weight for
their height.
Also at risk of obesity are people with
a low resting metabolic rare.
Those at risk should hold down their
calorie intake, particularly during periods
of rapid growth, such as during the fetus'
last eight weeks of gestation, early infancy, adolescence, and during pregnancy for women, she recommended.
Physicians must advise patients about
the fat in their diets. The percentage of
fat in the diet, rather than coca! calorie
intake, is a big contributor co obesity,
Howard explained.
Because the sympathetic nervous system regulates the mechanisms that tell
the body chat it has had enough co eat
or chat it needs to burn up calories,
anything that turns on the sympathetic
nervous system is beneficial. The best
thing is exercise.
"Diec is not the first thing, but exercise is," she emphasized . "Exercise has to
be a forever commitment."
Another thing that cums on the sym-

BUFFALOPHYSICIAN ANO BIOMEDICAL SCIENTIST

�Sprmg Clinical Da:,·

21

pathetic nervous system is the carbohydrate content in the dier, so people
should use carbohydrates as their chief
calorie source.
For people who have become obese ro
a point where it's affecting lifo expectan·
cy and health, strong consideration has
robe given ro the possibility of performing surgery, Howard noted. 1'\·o pro·
cedurcs, gastric bypass and vertical banded gasrroplasty, restrict food intake and
ro some extent impair food digestion.
They have a 60 ro 70 per cent success
rare.
However, gastric balloons haven't
proved safe or effective, she pointed our.
Howard mentioned rhar some new
drugs to aid weight loss may be available
in the next decade. They will be aimed
at increasing rhe mobili:arion of far,
mimicking satiety, and delaying gastric
emptying.

FORTHEGUT
FUELS

I

n certain conditions where the intestines aren't working properly, it may
help ro feed the intestines certain fuels
that their mucosa use best, said John L.
Rombeau, M.O., director of the Nucri•
tional Support Service at Philadelphia

Bl.:FFAW PHYSICIAN AND BIOMEDICAL SCIENTIST

Medical
Administration
Veterans
Center.
Patients with intestinal malfunctions
are often placed on a regimen of "bowel
rest" and fed in a way (such as intravenously) that attempts to bypass the
intestines.
Bue bowel rest has side effects, noted
Rombeau, who is also associate professor
of surgery at the University of Pennsylvania School of Medicine. The gut
begins to arrophv and the muscous lin•
ing of the intestines begins ro function
poorly.
Studies show that in selected conditions, it may be preferable to feed the intestines certain fuels char the mucosa use
best.
For example, glucamine, a non-essen•
nal amino acid, is seen as the preferred
fuel for the enterocytes, the cells that line
the small intestine, he explained.
Shorr-chain fatty acids are rhe preferred fuels for the colon, with soluble
fiber, such as pectin, as a precursor.
When part of the intestine is removed,
the addition of pectin to a liquid diet improved adaptability of the remaining portion of the intestine, Rombeau explained. Pectin also decreased diarrhea.
The shore-chain fatty acids improved the
strength of the colon.

EMENTS
L
NORMAREQUIR

I

t's difficult to establish nutritional requirements, noted Jorge E. Albina,
M.O., associate director of the Nutritional Support Service of Rhode Island
Hospital.
Minimum requirements arc defined as
the minimum intake that will maintain
adequate function and health, explained
Albina, who is also assistant professor of
surgery at Brown University.
But adequate for what, he asked. ls the
goal to reduce dietary diseases such as
scurvy? To maintain good health? To
reduce the risk of other diseases such as
cancer?
For hundreds of years, we've been try•
ing to figure out what kinds of foods and
how much food people require. The first
recorded nutritional allowance was written in 1753 when British sailors were told
to drink an ounce of lemon juice a day
to prevent scurvy.
Recommendations have changed over
the years, and today different dietary
boards disagree on minimum nutritional
requirements.
"If we try to answer the same question:
'How much food does man require?; I
chink we still don't know, but we're learn•
ing pretty fast," Albina concluded.
SUMMER 1%~

�Medical School

22

Health Manpower
Will we have enough doctors?
How many is enough?

BY CONNIE OSWALD smFKO

W

ill we have enough do ctors in the
future ?
That's a hard question to answer
since no one has yet decided how many doctors we need, according ro George E Sheldon,
M.D., professor and chairman of the Department of Surgery at the University of North
Carolina at Chapel Hill. And the kind of
doctors we'll need in rhe future changes with
every scientific breakthrough.
Sheldon discussed "Health Manpower the Future Challenge" March 23 ac the indu ction ceremony of the UB chapter of
Alpha Omega Alpha, the national medical
honor society. He is a regent of the American
College of Surgeons and chairman-elect of
the American Board of Surgery.
"Nobody has ever decided how many doctors we need,"said Sheldon, a trauma surgeon.
"There's no question we've got more than we
did 25 years ago, but we didn't have enough
then."
There was a time when medical schools
were turning out large numbers of doctors.
Back at the turn of che century, standards
were so low chat anybody who could pay the
tuition could enter medical school.
Then, the Flexncr Report, which urged
reform in medical education, was published
in 1910.Standards were raised, closing down
some schools and causing a shortage of do ctors. Between 1920 and 1950, there were less
than 120 physicians for every 100,000
Ameri cans, Sheldon said.

SUMMER 1989

"Nobody has ever
decided how many
doctorswe need,"
said Sheldon, a
trauma surgeon.
"There's no question
we 've got more
than we did 25
yearsago, but
we didn't have
enough then."

Now there arc 200 physicians per 100,000
Americans, but that's only a few more than
we had at the turn of the century, he pointed
out.
If we assume tha t we have enough doctors
today, we're pretty good at predicting the
numbers we need. But we don't fare as well
in predicting what specialties will be in
demand.
Sheldon described a 1978 study by the
Graduate Medical Education National Advisory Committee, which was an extensive
and expensive project that projected the kinds
of doctors we'll need by 1990.
The study was right on target in predicting
the number of physicians we'd have - about
half a million, he noted .
"But it was off by a mile on all the
specialties," Sheldon said, because medicine
is changing so rapidly.
Back in 1978, no one predicted the importance that organ transplantation would have
today because cyclosporine, the drug that
greatly improved the success of transplanta•
tion, wasn't around yet, he said. And no one
had heard of AIDS.
AIDS is becoming a problem today, but we
have to keep it in perspective, he cautioned.
More people die on the nation's highways
each year than have died from AIDS since
it was identified .
in the futu re, She ldon noted, the aging
populatio n in this country will create new
demands for certain types of physicians. And

BUFFALOPHYSICIAN AND BIOMEDICALSCIENTIST

�Medical School

23

there may be a greater demand for sports
physicians.
He also outlined ocher trends:
■ Before the 1970s, health care was a "corcage industry." Doctors ope raced fee-for-service
solo practices. This was coupled with voluntary hospitals.
Now, the trend is toward group practices,
Sheldon explained, and hospitals have
become very fragile economic entities. During Texas' recent oil problems, hospitals closed
because they are very dependent on che
overall economy of an area.
■ Most doctors work 60 to 70 hours per
week, though females tend to work fewer
hours, he said. The number of women is increasing, which could mean that the total
number of hours worked by physicians will
decrease.

BUFFALOPHYSICIANAND BIO~IEDICALSCIENTIST

"Bur I think that women have kept the
quality of heal ch care up; Sheldon said. "As
the number of applicants (to medical schools)
dipped down, if we didn't have the interest
of rhe women, quality would have gone
down."
■ The retirement age of physicians, driven
by high malpractice insurance rates, has
dipped below 60 years old.
■ Medical
school enrollment
has
plateaued . No new schools are being built.
An important aspect of the medical manpower question is how much society is willing to spend for health care.
The U.S. now spends 12 per cent of its gross
national product on health care, while Brirain spends only six per cent, Sheldon noted.
But he pointed out that 86 per cent of what
Britain spends comes from the government

while less than half of what rhe U.S. spends
comes from the government.
And in Britain, patients wait 28 months ro
get a hip replacement or 26 monchs to have
a hernia fixed, he added.
"These are choices we make in sociery;
Sheldon said. "Health care is not going to get
less expensive as technology increases. \Y/e
have co decide how we'll spend our money."
Quoting Rashi Fein, Ph.D., a Harvard
economist, Sheldon said, "If we become comfortable with a culture char tells us that health
care is analogous to selling shoes, and that
the level of health spending and major allocation decisions are to be determined by marker
forces, rather than by a political or social
consensus, we will be comfortable with rationing."
•

SUMMER 1989

�Medical School

24

Timothy

Murphy,

M.D.

of diseases caused by microbes (such as
BUFFALO
IS EMERGING
bacteria, viruses, and protozoa), provides vital
AS LEADER
IN STUDYOF
research that contributes to vaccine development and to the control and understanding
MICROBIAL
PATHOGENESIS
of diseases.

B

uffalo is emerging as a major center in
the study of microbial pachogenesis, researchers here report.
That prominence is highlighted by a national conference held here in March that was
sponsored by the UB Microbial Pathogenesis
Graduate Group.
"We attracted many heavyweights in the
field ro the first Buffalo Conference on
Microbial Pathogenesis; said Timothy Murphy, M.D., associate professor of medicine and
microbiology and direcror of the graduate
group. "This attests to the nationa l respect
chat Buffalo has in the field, as well as to the
need to collaborate our efforts."
Microbial pathogenesis, which is che study

SUMMER 1989

Barbara H. lglewski, Ph.D., and Stanley
Falkow, Ph.D., national leaders in the field
were among rhe six speakers at the March
event.
lglewski is professor and chairman of the
Department of Microbiology and Immunology at the University of Rochester and president of the 15,000-member American Society
of Microbiology. She has contributed groundbreaking research in using molecular techniques for studying bacteria.
Falkow is professor of microbio logy, immunology, and medicine at Stanford University School of Medicine. He is known for his
pioneering work in the field using genetic
techniques in order to understand how a

microbe adheres to and invades a cell.
"Basically, there is a lot of pathogenesis
research going on in Buffalo and all over the
country," says Mu rphy.
UB's new graduare group, as well as the con•
ference, offers opportunities for researchers
scattered among several departments at UB
to organize and communicate with their
colleagues.
The UB Microbial Pathogenesis Graduate
Group includes 25 graduate students and 33
faculty members from the Departments of
Medicine and Pediatrics (Divisions of Infectious Diseases), Microbiology, Biochemistry,
Oral Biology, and Surgery.
"Tom Flanagan (Ph.D., chairman of che
Department of Microbiology) was instrumental in recognizing the need for such a group;
explained Murphy.
"le was formed in order to foster the exchange of ideas and technology among faculty members in different departments who
have interest and expertise in the study of
molecular biological aspects of infectious
diseases."
While many of the researchers in the
various departments study different types of
organisms such as bacteria, viruses, protozoa,
and other parasites, they ask similar fundamental questions ('What are the factors in
microbes chat enable them co cause diseases?')
and use many of the same techn iques regarding pathogenesis.
Interaction
among departments
has
facilitated the development of a vaccine for
the disease called Haemophilusinfluenzae a bacterial disease, unrelated to the flu, which
preys mainly on preschool ch ild ren and
causes bacterial meningitis, pneumonia, and
ocher serious conditions.
"This development is a potentially significant one," explained Bud Nelson, a postdoctoral research associate in microbiology and
biochemistry. "Previous vaccines were ineffective in children under two years because their
immune systems did nor recognize the vaccine and produce the necessary antibodies.
Currently there is a pha rmaceutical firm interested in resting the vaccine."

T

hrough this interaction among departments, Michael Apicella, M.D., professor

BUFFALOPHYSICIANAND BIOMEDICALSCIENTIST

�Medical School

25

of medicine and microbiology, steered Nelson
to David Rekosh, Ph.D., associate professor
of microbiology and biochemistry. Under
Rekosh's direction, Nelson learned a gene sequencing and cloning technique used in
Rekosh's lab in order to characterize the
specific protein for the new vaccine.
"It took about eight months to learn the
technique; said Nelson, "but once I had, l
rook what I had learned back ro the infectious disease labs at the Erie County Medical
Center and continued the studies ."
The technique of genetic engineering is a
powerful molecular biologica l tool that has
revolutionized the study of infectious diseases
in the past decade. Since the faculry using
these techniques are located throughout different departments, the graduate group allows
collaboration for research projects.
This collaboration, together with the conference, are examples of the type of interaction needed wirhin the field, both at the
University and nationally, Murphy said. •

- By Mark Marabella

A GLASS
OFMILKMAYHELP

S

leep disorders in che elderly are usually
complications of other problems and are
too complex ro be whisked away with
prescription drugs, said Troy L. Thompson
U, M.D., professor and chairman of the
Department of Psychiatry at Jefferson Medical
College.
Thompson made his remarks during the
second annual conference on "Current Issues
in Geriatric Psychiatry," co-sponsored by the
Division of Geriatric Psychiatry, Department
of Psychiatry, and rhe Western New York
Geriatric Education Center at UB. His was
one of five talks presented at the April conference in the Ramada Renaissance Hotel in
Cheektowaga .
"Conservative estimates indicate chat about
5 million elderly patients in this country have
a severe sleep disorder," Thompson said .
"For unknown reasons, the death rare
among people who 'often' use sleeping pills
is 1.5 times higher than that among
marched subjects who have never used sleep-

BUFFAlD PHYSICIANAND BIOMEDICALSCIENTIST

ing pills."
Thompson maintains char sleep disorders,
such as the common insomnia, are too complex co be whisked away by the hasty prescription of sedative-hypnotics or benzodiazepines.
He emphasized rhar, especially in older individuals, insomnia is usually secondary in
nature and arises as an aspect or complication of psychiatric, medical, environmental
or pharmacological events.
"Many sleep disorders, such as insomnia,
are merely a secondary symptom of a complexity of factors; explained Thompson .
"A patient's complaint of a sleeping problem
should trigger a comprehensive review which
includes that patient's medical history,
family background, and current lifestyle."
Many times, remedies for sleeping difficulties need not come from the medicine
cabinet or a doctor, Thompson pointed out.

An adequate dose of L-Tryptophan, an essential amino acid which is sometimes recommended as a hypnotic, can be obtained by
drinking a glass of milk.
However, if a sedative-hypnotic medication
is chronically needed to maintain adequate
sleep, the physician should regularly reevaluate the initial diagnosis, reconsidering
such possibilities as depression, anx iety or one
of a dozen ocher primary sleep disorders,
Thompson cautioned.
"Judicious use of sedative-hypnotics in the
elderly requires an understanding of drug
metabolism in the aged, as well as knowledge
of the differential diagnosis of distu rbed sleep;
he said, adding that "the clinician should be
familiar with the changes in sleep patterns
and sleep architecture that are seen in the
healthy elderly person."
•

- By Mark Marabella
SUMMER 1989

�Medical School

26

--

Luc Montagnier, M.D.

SUMMER 1989

FOCUS
ON BASIC
AIDSRESEARCH,
SAYSMONTAGNIER

"we

should put our research efforts
first in basic research; said Luc
Montagnier, M.D., the noted
French AIDS researcher, "because we still
don't know many things about the virus and
how it causes disease. It's very difficult to
design new treatments and also to design a
vaccine" without this knowledge.
Montagnier, a professor at the Pasteur Institute in Paris who identified the HIV virus
associated with AIDS, spoke April 12 at the
19th Annual Ernest Wicebsky Memoria l l..e&lt;:cure in Bueler Auditorium. The lecture is
sponsored by the Ernest Witebsky Center for
Immunology and the Department
of
Microbiology.
According to Montagnier, AIDS is not
caused, but only triggered, by HIV (the
human immunodeficiency virus).
He contends that the virus causes autoimmunity, in which the body becomes immune
to itself. The virus hides from the immune
system by mimicking che configuration of a
human cellular structure so that the immune
system can't discriminate between itself and
the virus.
HIV alone, in sufficient amounts, is enough
to induce the disease in susceptible humans,
Montagnier says. However, when the virus
dose is low, and thi s is probably the case in
sexual contact, then some co-factors may play
a role.
It's important to understand the basic
workings of the virus, but "at the same time,
of course, we have to deal with the disease
in patients and we should try anything that
works, even in an empirical way; Montagnier
said, referring to treatments that seem to work
but haven't yet undergone thorough study.
"If something works, we should cry it."
In all parts of the world the treatments are
the same, he said, and the best we've got is
an antiviral drug called AZT (azidothymidine). While it may be beneficial to a patient
for months or even years, it's not a cure.
Many other compounds are under Phase

BUFFALOPHYSICIAN AND BIO MEDICAL SCIENTIST

�Medical School

27

I trials, Moncagnier added.
The Ernest Wicebsky Memorial Awards for
proficiency in microbiology were given co
Alison Koehler, a medical student; Kevin G.
Cleary, a dental student, and Sam Jayanch
Samuel, a graduate student.
•

BETTER
THANEVER

l

ooking like a contestant on The Priceis
Right, Paul Lecat, amid applause and
cheers from his friends, ran down the
steps of Butler Auditorium to the podium.
He received an envelope, tore it open, and
jubilancly yelled out che good news - "Akron,
yeah!"
Lecac had just found out he got the residency he wanted in medicine and pediatrics
at Children's Hospital of Akron in Ohio. The
occasion was March Day, che annual event
where lase-year medical students find out
where they'll spend their residencies.
About 65 per cent of che medical students
got the best news they could have hoped for
- chey got their first choice of residency. And
a whopping 87 per cent got one of their cop
three choices.
Students aimed high and were placed in
some of che more competitive residency pro•
grams, such as Yale, Cornell, Columbia Presbyterian, Strong Memorial, and Johns
Hopkins.
"le was a very impressive match overall~said
Dennis Nadler, M.D., assistant dean of student affairs in the medical school. "It's going
•
to be very difficulc to cop."

Scott Bookner congratulates Joan Murray.

Peter Ostrow, associate dean, prepares for a second champagne shower .

./

Doug Sillart and David Bloom

BUFFALOPHYSICIAN AND BIOMEDIC AL SCIENTIST

Charlene Vita le and Kristina Hart share their happy news.

SUMMER 1989

�Medical School

28

NOBEL
PRIZE-WINNER
EXPLAINS
WORK

G

erald M . Edelman, M.0 ., Ph.D., D.Sc.,
winner of the 1972 Nobel Prize in
Medicine and Physiology,delivered the
annua l Edward Fogan Lecture in Neurology
on March 16 in the Albright- Knox Arc
Gallery . The lecture was sponsored by UB's
Department of Neurology.
Edelman discussed "Cell Adhesion
Molecules in Morphogenesis and Neural
Development."
In recent years, Edelman has worked in
neuroscience. He is the proponent of a theory
explaining development and organization of
the human brain, which is outlined in his
book Neural Darwinism: The Theory of

NeuronalGroup Selec1ion.
Before that, he worked in immunology.
Edelman received his Nobel Prize for his
discoveries of the molecu lar configurations of
the immunoglobulin molecule.
This work led Edelman to consider questions of how ou r immune system develops
specificity in recognizing objects chat are
foreign to the body. This ana logy has been
adapted co che nervous system.
Cell adhesion molecules, first described by
Edelman in 1977, are markers on the surface
of cells chat provide a framework by which
the billions of cells in the nervous system are
able co relate co one another.
These molecules provide the structure by
which the nervous system differentiates itself
from an immatu re mass at birth, incapable
of sensing its environment, to che more
mature nervous system able to respond to the
intricacies of its environment.
Edelman suggests chat cell adhesion
molecules provide the matrix by which cells
relate co one another, thereby creating specific
neurona l differentiation . By chis means, he
suggests a mechanis m by which selective parts
of the nervous system develop specificity for
vision, pain, temperature, memory or fine
motor coordination, etc.
Related to chis work is Edelman's theory of
neu rona l Darwinism. Just as adaptation co
the environment is the foundation of Dar-

SUMMER 1989

Gerald M. Ede lman, M.D., Ph.D. , D.Sc.
win's theory of evolution of species, Edelman's
theory proposes that brain development is
based upon competition for survival among
neural cells and response co stimuli in the environment. Those that are used survive while
unused ones do not .
Cell adhesion molecules provide che structure that allows cells chat are to be programmed for a specific function to relate to
one another. Those areas that do not develop
affinities for one another do not survive.

This theory of how cells relate to one
anothe r and how they differentiate is so important that some people speculate chat
Edelman may be in line for a second Nobel
Prize.
Edelman is the Vincent Astor Professor at
the Rockefeller University and director of the
Rockefeller University Neurosciences Institute. He is also scientific chairman of the
university's neurosciences research program. •

- 8)' Michael £. Cohen, M.D.

BUFFALO PHYSICIAN AND BIOMEDICAL SCIENTIST

�Medical School

29

Tai-Hwang M.
Fan, a fourth-year
student, represented UB at the
eighth annual
Medical Student
Research Atvards
Program sponsored b-v the
Associated Medi cal Schools of
New York. The
May event was
held in Buffalo
for the first time.

Judith Tamburlin,
cl inical instructor,
right, explains her
work on an
anatom::, atlas for
the blind to
Stephanie
lovino, a
graduat e student.
The di spla::, was
part of the
medical sc hool's
first Faculty
Research Day
held April 25.

BUFFALOPHYSICIANAND BIOMEDICALSCIENTIST

SL:MMER1989

�Hospital News

30

Decked out in a frill:&gt;•hairband and sucking on her pacifier, Carley Mallon is cuddled by her parents, Peter and Diane.

Treating the Fetus as a Patient

S

cace-of-the-arc diagnostic and treatment
methods have introduced a new concept
in medicine - treating che fetus as a
patient.
That's the focus of the new Buffalo Institute
of Fetal Therapy, formed by che Perinatal
Center of Children's Hospital of Buffalo and
the UB medical school. The program is the
first of its type in New York Scace.
"The traditional field of fecal and maternal
medicine knows how co treat the mother and
normal pregnancies, and how co treat an abnormal pregnancy when it affects the mother;
explained Philip L. Glick, M.D., co-director

BUFFALOPHYSICIANAND BIOMEDICALSCIE1''11ST

of the program, "but it doesn't know how co
treat the fetus:'
In the recent past, a physician might be able
to predict chat a fetus would be born with
an ailment, but there was little he could do
about it. Now he can cake some action, explained Glick, who is also an assistant professor of surgery at UB and a pediatric
surgeon at Children's.
Sometimes physicians can treat a fetus
surgically or medically while it is still in the
womb. A more common action is co plan rhe
rime, place, and mode of delivery, and have
experts ready when the baby is born.

The ocher co-directors of the program are
Luther K. Robinson, M.0., director of clinical
generics at Children's and UB assistant pro•
fessor of pediatrics, and Amel S. Lele, M.D.,
director of the Women's Clinic at Children's
and UB clinical associate professor of
gynecology/obstetrics.
Glick said a wide range of fecal abnormalities can be identified using ultrasound
and rests that sample amniotic fluid, maternal blood, and fetal cells and tissue.
Among che problems chat can be detected
chis way are urinary tract obstruction,
thoracic masses, congenital diaphragmatic

SUMMER 1989

�Hospital News

31

hernia, abdominal wall defects, and spina
bifida.
Some are best corrected after a full-term
delivery, others may require a cesarean
delivery, and still others may require induced
prererm delivery for early correction outside
of the uterus. Some may require medical
therapy before birth and some may require
in-utero surgery.
The Buffalo program, Glick explained,
rakes a multidisciplinary team approach to the
unborn patient. The program has assembled
a team of experts consisting of perinacologists,
neonatologists, radiologists, cardiologists,
anesthesiologists, geneticists, ethicists, clergy,
and pediatric surgeons with various
subspecialries.
Rather than usurp the role of the community physician, the team members act as
consultants, Glick said.
The results can be very gratifying.

I

II

fit wasn't for you people at Children's
Hospital, we wouldn't have our baby
today," said Peter Mallon, gazing at his fourmonth-old daughter Carley.
Peter and his wife, Diane, 35, were thrilled
co find out she was finally pregnant. Their
joy turned to shock when doctors discovered
through an ukrasound test that the baby girl
Diane was carrying had a congenital
diaphragmatic hernia.
In this condition, the diaphragm (the muscle chat separates rhe chest from the abdomen) hasn't developed properly. Carley's
abdominal organs were in the chesc. Her intestines compressed her lungs, resulting in
small and abnormal lungs.
Although many babies with chis condition
also have other abnormalities, a cest called
amniocentesis and a thorough feral ulcrasound confirmed that Carley had no ocher
birth defects.
The doctors discussed the options with the
Mallons and they chose surfactant replacement and surgery after birth.
When the pregnancy was full term, labor
was induced and the baby was delivered
vaginally.
Surfactant, che soapy coating that prevents
the lungs from collapsing in between breaths

SUMMER 1989

Philip L. Glick, M.D.
and makes the lungs more pliable, was
placed in the baby's lungs before she rook her
first breath.
Surfactant replacement is an accepted
therapy for premature babies, Glick explained, but it's a new approach for babies
with diaphragmatic hernias. Babies with that
condition have lungs that appear similar ro
rhe small and sriff lungs of premature infants.
It apparently worked. Now the physicians
will go back to rhe laboratory and examine
whether rhe surfactant really did help Carley
and whether they can recommend it for other
children.
After Carley was treated with the surfactant, she was rushed off ro surgery where all
of her abdominal organs were removed from
her chest and placed back in her abdominal
cavity.
Her diaphragm was repaired with a piece
of plastic. That indicates how risky her condition was, Glick noted. When plastic is needed co repair the diaphragm, the mortality rate
is almost 100 per cent.
After six weeks, the baby was discharged
from che hospital and sent home without
respiracory or feeding difficulcies.
"She's coming along real good - she's real
alert," Diane said. "She's lifting herself from
che crib and crying ro roll over a little bit."
"As far as we can tell, she's absolutely normal," Glick confirmed, and Carley's future
looks bright. "She will be an absolutely normal five-year-oldon the playground with normal lung capacity."
He stressed that it took team work. Work-

ing on Carley's case were Diane's obstetrician,
ultrasonographers and technicians in radiology, perinatologists and neonatologiscs,
geneticists, pediatric surgeons, a developmental pediatrician, house staff, operating room
and intensive care nurses, and the hospital
chaplain.
The Buffalo Institute of Feral Therapy is
modeled on a handful of similar programs
across che country, including the pioneering
effort of Michael R. Harrison, M.D., ac the
University of California at San Francisco,
where Glick did his general residency in
surgery and a fellowship in fetal surgery.
The Buffalo program was founded in conjunction wich the deparrments of pediatrics,
gynecology/ obstetrics, radiology and surgery
at UB and Children's. Its work, Glick noted,
is facilitated by che fact that Children's
Hospital of Buffalo is che only free-standing
children's hospital in the continental U.S.
with an in-house maternity division.
J.E. "Ted" Sribbards, Ph.D., president of
Children's, noced that pediatricians used to
wait as long as five years co carry our some
corrective procedures that are now carried our
in the first few days of life. Glick's work pulls
back chat riming even further.
John P.Naughton, M.D., UB vice president
for clinical affairs and dean of the medical
school, said rhe new program "represents an
important clinical addition to the Perinatal
Center chat has existed at Children's Hospital
for the past three years.

"It will provide added and needed services
for unborn children with feral abnormalities
and will stimulate research designed to prevent such abnormalities from occurring and
co treat those chat are not preventable."
"The future of fetal therapy is inspiring; according co Glick.
"As our understanding of the fetal immune
system progresses, the possibility of in-utero
transplantation of stem cells and whole
organs looms as a distinct reality. If che secrets
of fecal wound healing can be unraveled, the
scarless healing of the fetus may usher in a
new era for plastic surgeons. ln-utero fetal
nutrition may lessen the mortality and mor•
bidity of intrauterine growth retardation.
"The list just goes on and on."
•

BUFFALOPHYSICIANAND BIOMEDICALSCIENTIST

�Hospital Neivs

32

Struggling with Polio's Aftermath
BY MARK MARABELLA

H

en ry Bauld, 78, was struck with polio
as an infant in 1912. Although he
successfully thwarted this potentially
crippling disease, in his 50s he began to experience extreme fatigue and pains in his
shoulders. He couldn't walk any distances
without becoming exhausted. When he consulted his physician about what was happening to him, his doctor chalked it up to "oldage."
It wasn't until last year, when he first consulted the Erie County Medical Center's PostPolio Center of Western New York, chat Bauld
learned he wasn't alone in his affliction .
Bauld signed up for an appointment with
Frederick McAdam, M.O., director of the
center and clinical instructor in UB's Department of Rehabilitation Medicine.
Following Bauld's initial examination and
evaluation, McAdam and the center's
specialists prescribed individualized daily exercises and vitamin supplements. Bauld soon
discovered that he had renewed energy that
he hadn't felt in 25 years. Sudden ly, his
formerly diagnosed "old-age" was seemingly
in remission.
People who had polio as youths are now
suffering in their lacer years from chronic
muscle and joint pain, fatigue, weakness, and
breaching difficulties. They are being diagnosed as having "phantom pain" or symptoms
of "old-age," according to McAdam.
Because the number of post-polio patients
with these symptoms has steadily increased,
physicians have begun co realize chat polio
may indeed have effects that linger well after
a patient's initial onset and rehabilitation.
Over the past decade, more physicians and
researchers have turned their attention to this
syndrome.
McAdam began the ECMC clinic in Oc-

SUMMER1989

suffering from post-polio syndrome or
poliomyelitis.
McAdam stresses that the main objective
of the clinic is co help a patient mentally and
physically cope with this synd rome; there is
no miracle cure . The clinic emphasizes the
teaching of energy conservation
and
establishing functional limits for patients.
With correct diagnosis and treatment, there
is improved quality of life.
"Many patients who come to the clinic are
wiped out just from getting out of the car and
walking into our office,"McAdam noted. "So
what we try to do is help them to function
more efficiencly in everyday life."

P

Frederick McAdam, M.D.
tober 1987 with two Department
of
Rehabilitation compatriots, Carl Granger,
M.0., professor, and Byron Hamilton, M.O.,
Ph.D., clinical associate professor. The clinic
is now a division of the Neuromuscular
Diseases Clinic and Laboratories of UB.
At first, the clinic was held one afternoon
a month with two to three patients at the
most. However, starting in July, it will take
place biweekly (then weekly some time
thereafter) so that it can better meet the growing need for special post-polio medical care.
"The response to the center has been overwhelming," McAdam noted .
Since its establishment, the Post-Polio
Clinic of Western New York has remained the
on ly facility in the area which provides both
clinical care and valuable research for people

rescribed treatments vary with each
patient . While in Bauld's case a vitamin
deficiency was recognized, vitamin supplements aren't a common aid. Anaerobic
and stretching exercises also vary with a patient's co nditi on and needs. The specialises
at the clinic may even recommend orth otic
devices - canes, braces, and walkers - to
help conserve the energy of the patient .
There is already a lengthy waiting list for
treatment at the center. It is difficult co handle the high demand because the initial
evaluation and treatment is so time consuming and labor intensive . A physiatrisc,
neurologist, clinical nurse specialist, physical
therapist, occupational therapist, and social
worker may all work together on a single case.
Once a patient contacts the Pose-Polio
Center, a questionnaire is sent asking for the
patient's symptoms and medical history. Then
McAdam meets with each patient to assess
his or her problem using var ious tests, including X-rays, CT scans (computerized
tomography),
videoflu roscopy (barium
swallowing and monitoring), and ocher lab

BUFFALOPHYSICIANAND BIOMEDICALSCIENTIST

�33

Henry Bauld
work. Following this, McAdam and his staff
establish a specified program for each patient.
Most of the time, these programs are designed co endure for the duration of the
patient's life.
Overall, McAdam is pleased with the
clinic's effectiveness and patient satisfaction.
"We'remaking a difference in most people's
lives, and chat's what's important," McAdam
emphasized .
McAdam also pointed out chat while one
function of the clinic is to help sufferers cope
with this debilitating condition, the other
function is to gather and evaluate valuable
evidence concerning the syndrome . At this
time, there is very little known about post-

BUFFALOPHYSICIAN AND BIOMEDICALSCIENTIST

polio an ,d there is no specified cure for the
syndrome.
The March of Dimes estimates from polio
records ,chat there are somewhere in the
neighborhood of 500 post-polio sufferers in
the West,ern New York area alone. However,
McAdam believes there are probably twice
chat number because many with this affliction still think it's just aches and pains from
old age. This is why educating che pub lic is
another important function of the clinic.
Donald O'Conner, president of the Polio
Survivor Support Group of Western New
York, maiintains a symbiotic relationship with
McAdams and the Post-Polio Center at
ECMC. O'Connor's group helps educate and

inform potential patients - as it did with
Bauld - of the center's availability. In cum,
McAdam recommends that patients join the
support group.
The condition of most patients affected by
post-polio syndrome usually isn't life threatening, says McAdam. However, those patients
who had previously been afflicted with Bulbar
Polio - polio which affects the diaphragm,
incercostal muscles (voluntary muscles
between the ribs), or the muscles involved in
swallowing - can be affected more seriously
by post-polio syndrome. They may experience
respiratory disorders and difficulty with
breathing
which can indeed be life
threatening .
•

SUMMER 1989

�People

34

LEONFARHIJOINS
RANKS
OFTHEELITE

L

eon Farhi, chairman of physiology, has
been named a distinguished professor by
the State University of New York for his
years of work in human lung gas exchange
and the human circularory system.
The prefix of distinguished professor is considered to be the highest academic title in the
SUNY system and is held by only about 50
professors. Farhi joins the ranks of poet and
literary critic Leslie Fiedler, Gerhard Levy of
pharmaceutics,
Felix
Milgrom
of
microbiology, Hermann Rahn of physiology,
and Eli Ruckenstein of engineering, among
others, as UB faculty who are distinguished
professors.
The honor "recognizes his tremendous contributions to both the scientific world and the
University," noted John Naughton, vice president for clinical affairs and dean of UB's
medical school. "We feel honored that he was
so recognized and it indicates that the efforts
he has made and chat the school has made
have been recognized."
Farhi joined the medical school more than
30 years ago.
"I was offered a job here in '58 and have
been here ever since; he said with a content
smile. "I have always been interested in the
heart and the lungs and also in the effect of
gravity on the heart and lungs."
Sitting in his office, Farhi swiveled in his
chair and pointed out the window on his
back wall. "See that?" he asked, as he pointed
to a cylinder on a circular track, surrounded
by a moat of calm water which in turn was
circumscribed by a running track.
"That's a human centrifuge. We are the only
University in the free world ro have one."
Farhi explained chat cest subjects sit inside
the capsule as it revolves. Centripetal acceleration from the revolution mimics high gravity situations, up to the equivalent of seven
times the earth's gravitational field.
What Farhi is currently working coward is
a June 1990 shuttle launch. He will be
studying blood flow in the astronauts before,
during, and after their flight. Sound cumber•
some? Needles and blood samples sticking out

SUMMER 1989

Leon Farhi, M.D.
everywhere?
Not quite. "We have developed a technique
chat allows us to measure the amount of
blood the heart pumps out without putting
any needles into the subject," he said.
Farhi's technique requires the subject co
breathe into a bag.
"We have developed a sec of mathematical
formulas that allow us to use the rate at which
CO 2 accumulates in the bag to calculate the
amount of blood that brings it there," Farhi
said. "If I know how much CO 2 reaches the
lungs every minute, I can calculate the
amount of blood going through the lungs ."
The amount of blood going through the
lungs, he said, is the same as the amount that
the heart is pumping out.
The experiment itself, Farhi ex'])lained,consists of looking at the heart's output under
different amounts of stress while the
astronauts are in space and comparing that
ro their cardiac output on earth both before
the flight and after it.
"The heart is an organ which is supposed
ro regulate itself. In order ro find whether it
is acting adequately or not, we look at subjects at different levels of exercise and determine whether cardiac output is appropriate
for that level," Farhi said.
"We look at the cardiac output as a function of the power output of the subject."
The subjects work out on an exercise bicycle hooked up to a power generator. On earth,

each subject is tested ro determine maximum
power output. In space, they will be tested at
30, 60, and 90 per cent of maximum, he
explained.
"Out technique looks at an astronaut before
flight as a baseline, then follows up on him
or her every day in flight, and provides special
emphasis after the return to earch; he said.

T

he problem that Farhi is looking into is
known as cardiovascular deconditioning.
What it involves is the heart's adjustment to
zero gravity and its subsequent readjustment
to earth's gravitation.
Problems resulting from cardiovascular
deconditioning affect the astronauts after
they return ro earth. They have to do with
the body's ability co return blood ro the heart
from its tissues, especially the legs.
"Man has developed a mechanism which
allows us ro make blood come back against
gravity," Farhi said. In space, he explained,
there is no gravity and so the body's methods
of pulling blood back up from the legs in to
the heart are "unlearned."
"It's like riding the tiger," Farhi explained.
"As long as you keep riding, you're all right."
But "if the astronauts stand up without
chose mechanisms once they are back on
earth, the blood accumulates in the lower part
of their bodies. If it's down there, then the
heart doesn't pump it back and the brain
doesn't get the right amount of blood."

BU FFALO PHYSICIAN AND BIO MEDICAL SCIENTIST

�People&amp; Research

35

Farhi said chat chis can lead to fainting in
asrronaucs after chey return to earch. "That
rums out to be a rather important problem
for NASA because it amounts to a loss of che
inborn ability to cope with the effects of
gravity."
Five astronauts, three payload specialises,
and two mission specialises have been training for this flight since 1984, when they
visited UB to gee a chance to use Farhi's
equipment. Two of che payload specialists and
both mission specialists will fly on the summer 1990 flight while che ocher payload
specialise will fly at some time in the future.
The experiment was supposed co be conducted on a summer 1986 shuttle flight but
was postponed, due to che disaster which
befell the Challenger, on which UB alumnus
Gregory Jarvis was flying.
Along with preparing for the NASA flight,
Farhi is conducting other lines of inquiry.
"We've been involved recently with the
problem of rediscriburion of blood in che
lung; he explained.
"If you have an area of the lungs char is not
breaching properly, che body shunts blood
away from rhose pares to the healthier parts
of the lung."This happens in emphysema and
pneumonia, among ocher diseases, Farhi said.
The equipment in Farhi's facility was paid
for by che Department of Defense almost 20
years ago. Besides the centrifuge, which is
used for studying the effects of gravity and
pressure on man, there is a swimming tank
chat is used co investigate man's reaction co
temperature.
Near the centrifuge and swimming tank,
there is a diving tank which is being used by
Claes Lundgren, also of physiology, co study
the consequences of pressure on man.
"ln the late '60s; Farhi said, "the Depart·
ment of Defense decided it would be a good
idea if there were a few centers across the
country char could be mobilized in case of
a national emergency. Thar was Project
Themis.
"Our project was environmental physiology.
We proposed to study how various environ menta I factors, such as gravity,
temperature, pressure, oxygen levels, etc., affect man and his performance."
He said che only Defense Department in-

BUFFALOPHYSICIANAND BIOMEDICALSCIENTIST

volvement was to help scare the program. The
agency provided the start-up coses for the
facility so chat in case of national emergency,
the Defense Department would be able to
turn co Farhi's group for specialized research.
lnicially, he had a grant with the Air Force.
Currently, he is being supported by the National Heart and Lung Institute. Farhi said
he has never done classified research.
Farhi's well-traveled career has carried him
far from his native Cairo, Egypt. He attended college and medical school in Beirut,
Lebanon.
He was a postdoctoral fellow at the Trudeau
Sanacorium, in Trudeau, N.Y.. 1952-53; che
University of Rochester department of
physiology, 1953-54, and the Johns Hopkins
University, 1954-55.
Farhi was also an instructor at the Hebrew
Universicy-Hadassah Medical Center in
Jerusalem immediately before arriving in
Buffalo.
In 1983, Farhi was named the Western New
York Heart Association "Man of the Year"
and in 1978 received the medical school's
Stockcon Kimball Award for teaching,
research, and service.
Chairman of physiology since 1982, he was
recently appointed co his third term.
•
- By David M. Snyderman

DETEOING
'SILENT'
AILMENTS
IN INFANTS

R

outine ultrasound screening of infants
could lead co earlier diagnosis and treatment of significant, yet "silent; urinary
tract problems in more than 47,000 infants
born annually in the U.S., according co
researchers at UB.
The projection is based on the investigators'
identification by ultrasound of significant
kidney problems in six of a group of 437 apparently healthy infants participating in a
study reported in Pediatrics.
The UB researchers said chat if ocher
studies show similar results, the medical profession should consider recommending chat
che use of ultrasound co check infants for
urinary trace problems become a routine

pediatric screening procedure.
The cost of the rest, which can be done in
less than IO minutes, is about $35.
The researchers, led by Jacob M. Steinhart,
M.D., UB clinical associate professor of
pediatrics, turned co ultrasound to dececc a
group of problems chat account for the
highest incidence of human birch defects. An
estimated IOper cent of all humans are born
with some form of genitourinary problem.
Despite chac prevalence, the researchers said
that in private practice they continued co encounter "significant numbers of children in
whom renal disease had escaped diagnosis until an acute illness, perhaps unrelated,
prompted investigation of the urinary trace."
They added, "\Viedecided co undertake chis
study to determine whether it would be feasible and cost effective to screen apparently
healthy infants with ultrasound in an effort
to diagnose renal abnormalities that might
be helped by early treatment."
The researchers concluded chat "there are
a significant number of infants harboring
silent urinary trace abnormalities chat can be
dececced by ultrasound at a relatively low
cost."
Referring co the six infants in whom significant problems were identified, chey added: "le
seems likely rhac che monetary cost as well
as the morbidity would have been greater had
these infants' problems not been diagnosed
until they had become infected and/or progressed to varying degrees of renal insufficiency."
Referring co the incidence of significant problems of l in 73 in their study, they said "one
could extrapolate chat, of the approximately
3.5 million babies born in che Uniced Scates
each year, more than 47,000 would have significant urinary tract pathologic conditions."
Also participating in che study were Jerald
P.Kuhn, M.D., UB professor of radiology and
associate professor of pediatrics; Bernard
Eisenberg, M.D., clinical associate professor
of pediatrics; and three clinical assistant professors of pediatrics: Russell L. Vaughan,
M.D., Albert J. Maggioli, M.D., and Thomas
F. Cozza, M.D. Kuhn also is head of che
Radiology Department at Children's Hospital
of Buffalo.
•
- By Arthur Page

SUMMER 19S9

�Classnoces

36

for his efforts on behalf of the care
of physically deformed children
by organizing voluntary surgical
reams willing ro rravel into rural
Mexican communities .

1930s
Richard C . Batt (M'36) • a
retired radiologist, writes, "The
past three years of my retirement
have been successful as a volunteer in helping to rehabilitate
selected brain-damaged patients
through computer usage."
Bernard St e ll (M '36) • a retired
psychiatrist, keep s active by
teaching photo amateurs at a
community college and by creating phoro slides char bring him
honors. "I won an honorable
mention ribbon in an internationa l stereo exhibition for my
stereogram, 'Thar's My Tongue: Ir
is a high-speed sequence (three
figures) of a hummingbird in
flight with its tongue sticking our.
In rhe PSA International Traveling Exhibition, I was awarded a
second place ribbon for my
srereogram, 'Red Lipped Clown'
a 3x magnification of a water
droplet with an image of a clown .
A water droplet acts like a lens;
it projects an image of a clown
that is about 12 inches behind the
water droplet." Dr. Stell also won,
for the second year in a row, first
place in the December 1988 contest for the Sun Cities home
decorating contest.

1940s
Richard J. Buckley, Sr. (M'43)
• has recently been elected president of rhe New Voice Club of
the Niagara Frontier, a support
group for laryngectomees .

A lfred S. Evans (M'43) • was
elected vice president (president•
elect) of the American College of
Epidemiology . His busy schedu le
includes a paper at a Scientific
Conference on Epidemiology in

SUMMER IQ89

Ernest A. Fatta (M'63) • of
Woodland, Calif., is president of
the California Affiliate of rhe
American Heart Association for
1988-1989.

Richard C. Batt '36
Beijing, China, in April; being a
visiting professor ar rhe University of Valencia School of Public
Health in Valencia, Spain in June
and teaching the Graduate Summer Program in Epidemiology at
rhe University of Michigan in
July. "In August I will fish." Dr.
Evans is the John Rodman Paul
Professor of Epidemiology, Emeritus at Yale University. The third
edition of Viral fn/eccions of
Humans:Epidemiology
and Control,
(A.S. Evans, Ed.) was published
in March by Plenum Press, New
York, N.Y.

Clifford W. Gates (M'48) •
former ch ief of radiology services
and chief of outpatient services at
the Long Beach Naval Hospital,
is retired and living in Fountain
Valley, Calif.

1960s
Jack C. Fisher (M'62) • has
been selected by the San Diego
County Medical Society as Physician/Cit izen of the Yca·r. The
society cited Dr. Fisher's contributions roward establishing a higher
regard for the medical school by
community physicians, and also

Jeffrey Kahler (M'66) • was
recently elected to serve a oneyear term as president of the
medical sraff ar Sr. Joseph Hospital, Cheekrowaga, N.Y. Dr.
Kahler is rhe director of the
hospital's orthopaedic surgery
section.

1970s
Denni s E. Stemp ien (M'73) •
was appointed associate company
medical direcror of clinical medicine at the General Electric Company in Fairfield, Conn.
Melvin Pohl (M'76) • of St .
Louis Park, Minn., is medical director of rhe Pride Institute and
co-chairman of AMSAODD' s
Third National Forum on AIDS
and Chemical Dependency.

Barlow S. Lynch (M'77) • has
a private urology practice in
Washington, D.C.,and is an assistant professor in the Deparrmenr
of Urology at George Washington
University, Georgetown University, and Howard University.
Ira L . Sa lom (M'77 ) • writes, "I
am enrolled in rhe J.L. Kellogg
Foundation Sponsored Advanced
Management Program for Clinicians at the NYU Graduate
School of Public Administration."

Pete r E. Shields (M'79) • is a
fellow of the American Academy
of Orthopaedic Surgeons.

1980s
Thomas J. Lane (M'81) • writes
from Bristol, Conn., that his
research interest is in chronic
fatigue syndrome. Dr. Lane is an
assistant professor of medicine at
the Universiry of Connecricut
Health Center.
Richard L. Co llin s (M'83) •
has been named medical director
at the Northwest Buffalo Community Hea lth Center, a federally funded medical center for the
medically underserved .
Kenneth Ja y Ru th (M'83) •
writes, "I am in solo pracrice in internal medicine in a San Diego
beach community. My practice is
growing rapid ly and I'd be most
interested in having a fellow UB
grad as an associate. Please call
(619) 226-4524." His address is
5825 Caminito Del Estio, La Jolla,
Calif., 92037.

Brian Gale (M'87) • writes, "I
am a nuclear medicine resident at
the Albert Einstein College of
Medicine and will begin a radiology residency at New York
Medical College in July 1990. I
will marry lawyer Marla Kirsh in
Augusr '89."
Tina Marie Gardne r (M'87) •
writes from Fairfield, Maine, "We
moved from New York City to
Maine; we love the fresh air and
free parking. This program is
much berrer too?' Dr . Gardner is
a resident physician in the MaineDarr mou rh Family Practice
Residency Program at the Kennebec Valley Medica l Center.

BUFFALOPHYSICIANAND BIOMEDICAL SCIENTIST

��CAMPUSMAIL
998

MR. CHUNG•KAI HUANG

HEALTHSCIENCE LIBRARY
ABBOTTHALL
CA...,PUSMAIL

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                    <text>Vol. ~J. So. l

Autumn

1989

�STAFF
EXECUTIVE EDITOR
LJJ\:l\'ERSITY Pt..:BLIC"ATIONS
Robert T Marlen
BUFFALOPHYSICIAN EDITOR
Conme Os"ald Stofko
ART DIRECTDR
Al J. 1-:e er
ADVISORY BOARD
Dr. John :\aught• ·
. mnan
Dr Harold llroJ,,
!\Is. :--;ancy Gh..-co
Dr. James Kanska
Dr )o&lt;cph L. 1-:un:
Dr Charles Pagane1!1
!1,1r.Paul D. Pat«scn
Dr Antoinette Pecers

Dr. Charles Pru&lt;1
Dr. Lu, her Robon;,:,n
Dr. Thomas Rosenthal
Dr. Saleda Surcsh
Or. Burtl&gt;rl Smgc-rman
Dr. Stephen Spaulding
Dr Ndsc,n Torre
\1r Edward \Ven:ke
Dr J1n ,rr Y,r,

WRITERS
M ,rk \1.ir ,~ [;
[)· J !1,1.';urllcrman
ILLUSTRATOR
L H.
PHOTOGRAPHERS
~ancr J. Paroso

DearAlumniandSupporters
of the UBmedicalschool:

T

he 1933-39 academic year was a stellar one for the school's
faculty \'i,'c were honored that the SUNY Board of Trustee,
and the chancellor singled ouc three faculty memhcrs for
special recognition.
Dr. Leon Farh1, professor and chairman of phys1ology, was
awarded the title of Oiscmgu1shed Professor. This is pcrhap, the
most ~igrnficant award char can be given to a SUNY facultv member
since its bestowmenc indicates significant achievement in all phases
of academic life and extraordinary evaluatiom by peers world-wide.
Dr. Murray Ettinger, profc,sor of h1ochemistry, wa, awarded
a Discmgutshed Teaching Professorship. :\1urray, an accomplished
academician in all re,pe..:ts, has always excelled as a dedicated
teacher of medical, dental, and graduate students. His LOmm1rmcnc
to teaching is well known and he is fully deserving of thb spcual
rccogmrion.
The third farnlty mcmher, Dr. Charle, Severin, assoLiatc profc,,or of anatomical science,, was awarded the ChanLellor\ \fedal
for excellence in reaching.
Chuck Severin has provided superb leadership smce coming
to Buffalo, and together with Dr. Farh1 and Dr. Ettinger, is alway,
regarded a, among the ,crongest of the fine cadre of teachers and
cducators we have in the medkal school.
I am sure chat ca..:hof you Join me m congratulating cl1L-se
three
fo.:ulcymemhcrs 111their indindual and colk'Cnve accomplishments,
and in rendering our thanks for their efforts on the schtx)l's hchalt.

Simon Tong

Bob\\

1,n___,
Li

TEACHING HOSPITALS
A'SD LIAISO!'.S
Bauv.a \r.:•.:r.i.:~ Adm:.

-·r .

\ 1ed,cnl Center
Buffalo General Hosp1tal, M,l, \hau

John Naughton, M.D.
Vice Pro~sulenr
1nr Clmical Affain
Dean, S.hool of .\lediunr and Riomedical \cienc·cs

Buffalo Veterans AJmm1strauon

!\1cJ,cal Center, John Po,ll,
( h!Jrt·n's Hospotal, Karrn Dr,Ju \u oenk
Enc Count-,: \1cd1Cal( t1.c1.:•".
\!anon \forwnousb
!\lerq Hos~,11al,Ch,.,k Tele«o
\l,llard hllmorc Hc,spn ,!,
Debo-rahFenn
Roswell Park !\1cmoroal lnsraute, Jud,Ru.,
S1,1ers Hosp11al,D,-nnrs McC.mll)

Pmdw:,db-, rh, Dn mon of l,noi-mm Rela
"'"" ,n =ocu,uon u, ch ch.-S..hoolf .\l,,du. nc
urul Bo•medocal'i.:1ence,.Stace l nn t'NI) of
:\,u )O'fk at B1&lt;jjolo.
THE! Bl FFALO PHYSICIA:S: A'\D 810~IEDICAL SCIE:S:T!Sr (U:,PS 5&gt;l•ll601
Summer !OS&lt;), \\,lume
'\uml--er 2
P bli-.hc.:dfi\'c umt.~ i.1IJt1ual1v:
Spring,
~ummcr, Autumn. Earlv \'C.'tnt(!'r,
:id L.::ttl•
\Xm«r h 1he School oi !l,l,d,une and
B1omc.~1cal X1cnces, State l mvcrstty vf
~""' Y.1rkat Buffalo. IH&gt; !\hon S1ree1,
Buffalo, ~c"' fork 14214.Third das 1"ulk
rosu~e paid at B"ffalo, :--.;ev.
York. Send
address changes 10 THE BlA'fAIJ..)
PHYSICIA'\
A:--.;D BI0!\1EDICAL
SCIE:--.;TJ$T,140 CFS. AJJ,1,on, HJ5
!\bm Sir«c Buffalo. New )c,.k 14214

n.

Dear FellowAlumni/Alumnae:

T

he first D1stingu1,hcd Alum nu., ha, hcen chosen hv che Ad
Hoc Commim:c for l9SQ, The m1ard will be presented co
Dr. Gt•orge \\'. Thorn, cerrnmly a worthy cho1Ce of one
whose ,ntcrnanonal reputation ha, brought muLh h,mor to our
medical ,,hool.
\X'carc msmuting a program for alumni mtcnicws of pm,pcctlve candidates for medical school admission in distant cities, designed for students who find it difficult to come to Buffalo for their
1nterv1e11.\\'ould you be interested in bcmg of ,ervice in vour cit\,
1fsuch a situation arises? f.:indly contact Dr. John Richert at the
Alumnt Offi.:e. \\'c would be most grateful for your help.
Please mark Apnl 28, 1990 nn your calendar for next vcar\
Spring Clinical Dav and Alumni Reunion \X'i:ckend. Weare planning a great smnulacmg program. :\-1orc about chis later.
Through your support, we ha,·e reached an all-ume mcmbcr•
ship high ,,f 1,474 ducs-paying mcmhcrs, mcluding 53 Life \kmbcr
,uhscrihers.
It is an honor to serve you as president for the 1939-1990term.
Please contact us with any problems or suggestions you may have.
~

~

0'

- Sia.~,,,,

Joseph L. Kunz, M.D.
President

�BUFFAID

\ ol. 21, ~ o. 3

PW-§!~l6N

l

Autumn

19t!9

Features

II

~ ~r/4

The history of trauma care,
Page 18

IJ

Notjustbecauseit's there.Growing up in the shadow
of the Alb orz Mountains in Tehran, Fero Sadeghian,
M.0., developed an early interest in mountain
climbing that lasted throughout his adult years. He
climb s not "just because it's there;' but because of
the challenge. "It becomes us against the mountain."
His mo st recent challenge: the remote and
trea cherous east face of Mt. Everest .

Likerubbingsnowon frost bite. A popular treatment
for "acute mountain sickness" may actually make
matters worse, according to John Krasney, professor
of physiology at UB.
We'renot hurtinganimals.The scientific community
must come together and convey this message to
the public: we're not hurting animals, we're saving
human lives, medical researchers are told at a campus conference.

Mountain medicine,
Page 10

Departments
MedicalSchool News. From rags to stitches: John
Border gives a history of trauma care in the 1989
Stockton Kimball Lecture. School graduates its
143rd class. Pull out all the stops in treating patients,
a noted pediatri c surgeon advises.

143rd commencement, Page 20

■

Specialsection. Meet the Class of 1993 - a directory of this year's incoming class begins after page
24.

Thi s year's reunion classes generously pledgFDedAlumni.
a total of $102,220. All IOclasses sat for portraits
that are featured on pages 26-29.

Mountain cl1mbmg, Page 2

�2

Fero Sadeghian
to mountain
the beauty

By

MARK

is drawn

climbing

by

&amp; challenge

MARABELLA

up in the shadow of the
Alborz Mountains in Tehran, Fero
Sadeghian, M.D., 53, developed an
early interest in mountain climbing
that lasted throughout his adult years.
Sadeghian, a clinical assistant professor of surgery at UB, has climbed
the Alborz Mountains in Iran, Mont
Blanc in France, Kilimanjaroin Africa,
Growing

AUTUMN

IQ89

~.-

the Andes in South America, and even
a small peak on the southwest face of
the legendary Mount Everest - the
highest mountain in the world.

Unnamed

peak

In Himalaya
chain.

However, Sadeghian's highest and
BUFFALO PHYSICIAl-: Al-:D BIOMEDICAL SCIEl-:TIST

�most exciting climb u·as in Ma)·, 1988,
when he revmted Eierest and climbed
its remote and treacherouseast face.
There, completelyby chance,he met up
with another smaller expedition that
BUl+Al.O PHYSICIAN AND lllOMl·DICAI. 5'( ll:1'TIST

u·as one of only tu:oexpeditions in his,
tor)' to reach Everest'ssummit by way
of the eastface. Sadeghian'smedicalex,
pcrtise played a key role in the safe
return of these historic climbers.

Photos:
Fero
Sade&amp;hlan

,\l l l \11" 1•1~&lt;1

�(From top to
bottom)
Potala,

The
once the

home

of the

Dalai

lama;

climbers
three

the

drove

days

before
transferrin

g

equipment

to

yaks ; frostbitten
foot of a
member

of the

Americ a n /
British
expedition

a

a

.

a •

wile

Sadeghian himself did nor set out
to attain Everest's summit of 29,028 feet, he
trekked ro the h ighest altitude in his climbing
career-22,000 feet . Th e callesr peaks Sadeghian
had previously visited ranged from 15,000 to 19,500
feet. (The Hima layas are so high chat peaks be low
24,000 feet don't even gee named there .)
"To attempt the peak of Everest, a climber must
devote a great deal of time co its pur:-uit . It may
even be the culmination of a lifetime of preparation;· Sadeghian asserted . "I wish I cou ld make an
actcmpt, but I'm a surgeon by profession and find
it difficult co make time for ~uch a \'Cnture.

Bl FFALO PHY:c-lCIA:S:
A'D

Bl0~1EDICAL SCIE:S:TIST

�5

"Bue still, I've always found mountain climbing

co be an exhi larating way co recharge one's batterv
from the day-to-day monotony that everyone muse
endure;' he observed.
"The attraction is not merely because 'It is there'.
The mountain attracts a certain breed of people those who seek natural beauty chat is both isolating
and challenging. There is a unifying camaraderie
among mountain climbers that transcends race,
religion, and politics . le becomes us against the
mountain ."
Certainly, Everest - called Chomolungma hy
the locals, meaning "Goddess Mocher of the Earth"

BL"FFAL.0PHYSICIA:-.:A:--:O BI0:'-1EDICAL SCIE:-;TJST

- represents what Sadeghian seeks in his mountain pilgrimages.
Everest separates Nepal from Tihet and has three
faces: north, cast, and southwest.
The southwest face can be seen from Nepal and
is the conventional way of climbing Everest . This
face was the first path co the summit con4ucred by
the New Zcalander Sir Edmund Hillary, with the
Tibetan Sherpa, Tenzing Norgay, in 1953.
In 1975, Sadeghian climbed co Everest's
southwc!:&gt;t base camp with a small group t h at inc.lude&lt;l two other individuals from UB's medical
school - David Greene, M .D., professor emeritus

Members

of

Sadeghi a n's
group with
members

of the

American

/Brit­

ish expedition.
Sadeghlan

is

third from right.

no

ace•

�of medicine, and Winfield Butsch, M.D., clinical
professor emeritus of surgery. Sadeghian always
dreamed of one day revisiting Everest.
"On my previous climb of Everest my group went
through Nepal (where the southwest face base camp
is located). But this route has become coo commercialized, busy, and Lrowded," he recalled.
The north and case faces are approachable only through Tibet and attempts along chese routes
have been scarce.
"The cast face base camp in Tibet is more remote
and less traveled and I always wanted to sec Tibet,"
Sadeghian said. "fur many decades the ease face was
closed because of poor political conditions in Tibet
due to its relations with the Chinese; now with
what has recentlv happened in China it is unlikely anyone will be climbing there for some time to
come:'
The east face provides a significant challenge
because it takes days of trekking over high passes
to reach its isolated base camp.
Sadeghian's
month-long
trip co Tibet,
highlighted by his three-week ascent on Everest's
case face, was the culmination of many months of
preparation.
Sadeghian first contacted the Mountain Travel
organi:arion m Albany, Calif., eight months before
rhe trip to express his interest in dimbing Everest.
The organization then assembled a group of nine
climbers who expressed the same interest, secured
the necessary mountain climbing permits from the
Chinese government, and provided the group with
the supplies needed to trek in the Himalayas. All
expenses were paid by the climbers.
Six months before the climb, Sadcghian started
a rigorous workout schedule running six miles, four
times a week, with aerobic exercises in between, to
im:rease his !'-trengrh and stamina for the challenge
of Everest.
Sadeghian was appointed the phy~ician for the
group and was responsible for carrving antibiotics,
sutures, bandages, pain medicine (morphine and
Demerol), intravenous and ~urg1calequipment, and
a supply of oxygen. He was 101ned by his friend,
Nas Efrckhar, M.D., an orthopaedk surgeon at Columbia University. The group of nine was forrunate
because it is rare to have two doctors on such a
small expedition.

6

Sadeghian
and Eftekhar fle\\ into Beijing,
China, where they mer the other people with
whom they would spend the next four weeb.
The appointed leader of the climb was Bruce
Klepinger, a full-ume mountaineer. Other members
of the group included SI-year-old Jeffrey Davis from
Canada; 47-year-old Steven Ncgler, a retired U.S.
Air Force officer from Urah; 57-year-old Peter Anson from Minneapolis; 32-year-old Minnie Chin
from California, and John and Carol Goodman,
AUTUMI\

IY84

married and in their early 20s, from Texas.
From Beijing, the climbers spent several days
driving over narrow dirt roads along steep valleys
and climbing up 17,000-foot passes before they
reached Shigacse, the Tibetan town located closest
to the east face of Everest.
There they transferred their equipment from
their truck and three jeeps onto the backs of 17
yaks. Each yak was loaded with approximately 150
to 200 pounds of equipment.
The equipment included five double tents, three
larger rents, gas-burning stoves and lanterns, and
plenty of canned food.
Here they were joined by five Sherpas who were
in charge of the yaks. Sherpas are Himalayan
residents who, due to their climbing experience, are
hired to carry supplies and assist rhe climbers on
their trek.
The group was also joined by several Chinese
who were hired co cook, guide, and maintain an
established base camp.
The mix of the English, Chinese, and Tibetan
languages proved cumbersome. The translator for
rhe Tibetans was Mr. Chin, a well-respected mountaineer who had been a member of a Chinese expedition to Everest and had lose part of his nose
and right hand to frostbite. Another man, named
Mr. Jin, translated for the English-speaking
climbers.
To communicate with the Tibetan yak drivers,
the climbers spoke m English co Mr. Jin, who spoke
Chinese to Mr. Chin, who spoke Tibetan to the
yak drivers. The group traveled by yak for nine days
and set up a base camp. Then, carrying 35-pound
day packs, they set out to ascend Kangshung
Glacier.
Climbing along lateral moraines, where an immense glacier had deposited large amounts of rock
and debris from its gradual movement down the
moumian, Sadeghian and the others could see and
hear the thunderous avalanches of the east face.
The cast face of Everest is accessible only
through the Kama Valley, near Shigatse, which is
,urrounded by mountain passes averaging 18,000
feet. The terrain varies significantly. At lower
almudes, it's lush green dotted with wild roses, rail
poinsettia bushes, and turquoise lakes. However,
the terrain near the passes is cold. barren, and snow
covered.
When they had climbed to approximately
20,000 feet, the group split up. Five of the climbers,
who chose to rest their weary lungs and muscles,
visited a base camp char was established for the
group that reached the cop.
Sadeghian and three others continued climbing until they reached a rocky spur at 22,000 feet.
Herc Sadeghian's small group rested for some rime
and gazed at the impressive Everest, raking rare
photos from che ease face.
BCFFALO PHYSICIAK Al\D BIOMEDICAL SCIE:-.:TIST

�7

l
\
"

"These mountain climbing trips always bring
tremendous pleasure for me," Sadeghian reflected
with a smile. "Not only is the natural scenery and
landscape unparalleled, but the variety of people
one meets is always so diverse.
"During the day we share the dangers, frustrations, and unpredictabilities of the climb," he continued, "and at night around the fire we discuss the
day's events and plan the next day's goals. This is
the best part of the trip because it brings everyone
together like a family."
Meanwhile, the other half of Sadeghian's group
at the American/British base camp discovered
several climbers who were in desperately feeble condition.
"What happened was that these climbers got
stuck near the top without oxygen, food, or tents,"
explained Sadeghian. "They were unable to return
to their base camp at first because the weather and
their weakened reflexes prevented a speedy descent~
Returning from the small peak, Sadeghian's
group joined the other climbers
at the
American/British base camp.
It was here that Sadeghian first met the
American/British group that managed co put one
man on the top without rhe use of oxygen. Only
15 individuals have ever managed to go to the top
without oxygen and none before had accomBUFFAI.D PHYSICIAN AND BIOMEDICAL SCIENTIST

(From top to
bottom)
Sadeghian

and

companions
received

warm

welcomes

from

natives;
Sadeghlan

in

front of
Rongbuk
monastery

near

the north face of
Everest;
Camp

Frost

on the

way to Everest.

a es a

s a

AUTUMN l'l!\9

�8

(Top) Framed
against

the

Himalayan
peaks,

the

1,000 •room
Potala

r ises

1,000

feet

above the valley
and can be se e n
for miles;
(bottom )
Sadeghi an
watches
drivers
dinner .

yak
cook

plished ic from che treacherous
Getting to the Everest summit
face had been accomplished only
\\'as done by an American group
\'arJ in 1983.

east face.
by way of the east
once before. That
led by Andy Har-

In chc 1988 attempt, the man who reached the
top, Stc\'C Venables of Britain, made headlines
across Europe as the first European to reach rhe
summit from the cast face. And he accomplished
his feat on the 35th anniversary of Hillary's ascent.
But the attempt was not without its coses. All
of the climbers suffered frostbite to a \'arving degree.
One of them, Ed Webster, described his group's
traumatic events in a Januarv 1989 Sportsllluscraied
arricle.
\X'cbster was malnourished,
extremely
dehydrated, dcmorali:cd, and consramly in tears.
He was abo suffering from severe frostbite with
black toes and fingers .
Another climber, Robert Anderson, was also
suffering from frostbite on his fingers and toes, but
co a lesser degree. Venables, who reached the top,
suffered severe frostbice on his toes and nose.
For several hours, Sadcghian and Eftekhar cared
the best they could for the climbers' injuries, us-

ing medications and bandages chat Sadeghian was
rnrrying on his back.
"\X'hac they really needed more than anything
else;• explained Sadeghian, "were some words of
reassuran&lt;.e and some idea as to what to expect as
far as prognosis was concerned. At the time, I
choughc chac they mighc lose portions of their
fingers, toes, and nose, buc I tried co remain as
positive as I possibly could."
Both Webscer and Venables had to be carried
down the rest of the mountain by cheir Sherpas
on improvised litters. \X1hen they returned to the

BLFFAI.() PHYSICIA;\ A:S:D 810.\tEDICAL SCIE:--:TIST

�(Top to bottom)
Tibetans
friendly

are
and

maintain
serene

a
nature ;

9

two Sherpa
children

whom

the climbers
encountered

in

the T ibetan /
Everest

region;

John Goodman
(foreground)
Sadeghian
the foothills

and
In
of

the Himalayas.

ed very little, if any, medical treatment. Only a few
of the climbers suffered from cerebral edema and
required some oxygen, which is no rmal."
Sadeghian and his group returned safely down
the mountain, hiking over to the north face upon
their descent. From the north face the group traveled to Nepal, abandoning their yaks for some
wheels before eventually flying back ro the States .
One precious souvenir that Sadeghian brought
back from h is trek on Everest was a note, written
by Miriam Zieman, the medica l advisor from the
American/British camp. It was sent to Sadeghian's
camp via a Chinese runner and gave thanks for
the surgeon's treatment .

"May 20t h- 8:00 p.m. - Everest base ca mp "
"Endless thanks for your support and encouragement today . It was quite an unbelievable vision to
see your companions this morning after three
months of isolated company, but to find out that
two surgeons were on thei r way down (from a peak
just above our base camp) was very reassuring for
both the climbers and myself.
"It was very gene rous of you to help and advise
me. T he past few days were exasperating and it was
a great relief for me to have you here . Needless to
say, the climbers enjoyed your care and expertise
and felt better after your consulta tion."
United States, Webster had ro have all the fingertips on his left hand amputated, as well as three
on his right hand and pares of three roes on his
left foot. Venables lost three and a half toes on his
left foot .
"Fortunately," noted Sadeghian, "my group need-

BUFFALO PHYSICIA1' AND BIOMEDICAL SCIENTIST

"One thing I enjoy about being a physician,"
Sadcghian commenced, "is that, regardless of
politics or language barriers, doctors are always well
received by people . Closed doors always are
opened for physicians."
•

ALJfUMN 1989

��LIKE

RUBBING
SNOW
FRO! i I BITE

~
~

ON

By CONNIE OSWALD S1DFKO
ike rubbing snow on frostbite, a
popular treatment for "acute mountain
sickness" may actually make matters
worse, according to John Krasney,
Ph.D., professor of physiology at UB.
Acute mouncain sickness affects lowlanders who
travel to high altitudes where the air is thinner.
"The symptoms are terrible," said Krasney, who
suffered from the condition when he attended a
conference in Snowmass, Col., which is 11,000feet
above sea level. Acute mountain sickness is marked
by a severe headache, along with nausea, irritability, lethargy, severe fatigue, and trouble eating and
sleeping.
In the past few years, mountaineers have been
teaching climbers to treat the condition by
breathing into a paper bag . But that makes matters worse and could actually prove lethal, Krasney
contends .
His findings are important as more and more
people ski and hike at high altitudes. Bur, Krasney
emphasized, his research also has implications for
peop le with heart and lung diseases that inhibit oxygen intake.
The idea of breathing into a paper bag has been
promoted by neurologist Marcus Raichle of
Washington University in St. Louis.
Both Raichle and Krasney agree that the trigger for acute mountain sickness is a decrease in the
oxygen supply to the b rain. Raichle contends that
breathing into a paper bag increases the person's
intake of carbon dioxide, which dilates (widens) the
blood vessels in the brain. That allows more blood
flow, and therefore, more oxygen, to reach the brain.
But this dilation of blood vessels is the problem,
not a solution, Krasney explained in a paper
presented earlier this year during a symposium
sponsored by the International Society for Mountain Medicine in Lake Louise, Alberta .
ILLU

Bl.:FFALO PHYSICIAN AND BIOMEDICAL SCIENTIST

S TRATION

S: LI SA

H A N EY

II

�THE

MESSAGE

FOR

PERSONS

PLANNING

This dilation of blood vessels in the brain
ele,·ates
pressure in the capillaries (the tiny blood
12
vessels that connect larger blood vessels to tissues).
That causes a mild form of high altitude cerebral
edema - the brain tissues fill with fluid.
"Our data says there's already roo much
vasodilation" caused by rhe low oxygen level at high
altitude, Krasney explained. "If you increase carbon
dioxide, you make the situation worse.
"Normally, when you go to a high altitude, you
hyperventilate. You bring in more oxygen and exhale more carbon dioxide. Thar's a normal
response. And we think that has something to do
with the eventual resolution of mountain sickness
- we think it's the decline of carbon dioxide'.'
Krasney says he's upset that Raichlc didn't
publish his data in scientific journals before his
theory was presented in lay magazines such as
Discover.
"I think it's a good example of something that
could be very dangerous getting into the popular
literature." Krasncy said. While acute mountain
sickness is a condition that has plagued man for
centuries (Marco Polo described traveling over the
"Big Headache Mountains" in China), we haven't
made much progress in treating it.
Theoretically, administering oxygen should help,
but it doesn't help immediately, Krasney noted.
One option is to simply let the condition run
its course. Without treatment, most people recover
from acute mountain sickness in a few days or
weeks as they become acclimati:cd to the high
altitude.
However, the condition can develop into a lethal
form of high altitude cerebral edema or high
altitude pulmonary edema. Then the only thing
that can be done is to get the patient to a lower
altitude.
One treatment that mountaineers arc trying
now is the Gamow Bag, named after Igor Gamow
of the University of Colorado. The patient's entire
body from head co toe is placed in the portable
fabric bag, making him resemble a mummy. Then
the bag is inflated using a foot pump.
Thar increases the pressure in the bag, which
increases the oxygen saturation. In many cases, the
oxygen saturation is increased enough to begin
resolving the edema, Krasney said.
It's easier to prevent acute mountain sickness
than to treat it. The symptoms are brought on by
the failure of people to acclimatize themselves properly to high altitudes, Krasney explained. Once
a person reache~ 10,000 feet, he should take a full
day to ascend another 3,000 feet.

AL'Tl,MN

ICl8Q

GO

TO

TO
HIGH

ALTITUOES
IS THAT

THEY

SHOULOTAKE
CARE

TO

ACCLIMATIZE
PROPERLY
ANO

GO

SLOWLY.

UP

(By comparison, skiing areas in Western New
York arc only about 900 feet above sea level.)
The minimum altitude to get acute mountain
sickness is 8,000 feet - that's the height of Mexico
City. The condition can be lethal at 9,000 feet,
Krasney noted. Some people with underlying lung
problems could probably experience symptoms in
Denver, which is only a mile high.
He also pointed our that the cabin in a jet aircraft isn't pressuri:ed to sea level, only to the
equivalent of 7,000 or 8,000 feet. So passengers arc
mildly hypoxic, that is, their tissues aren't getting
enough oxygen.
"So if you get a headache flying from Buffalo
to California, there might be more reasons for 1t
than the wine you drank;' Krasney said.
"Thar's another aspect - acute mountain
sickness or hypoxia can really intensify the effects
of alcohol. If skiers make the bar the first stop, they
can be quite violencly ill."
Exercise can also exacerbate the condition,
Krasney and his colleagues believe, because circulation is severely altered at high altitudes. As blood
pressure goes up, it may produce an undesirable increa~e in brain blood flow, which causes a marked
elevation of pressure in capillaries. Thar can cause
a rupture in the blood-brain barrier.
"The message for persons contemplating going
to high altitudes is char they should rake care to
acclimatize properly and go up slowly; Krasney said.
"If they can't, they should certainly take ir easy for
the first few days at altitude."
Certain drugs to prevent acute mountain
sickness can be taken before traveling to a high
altitude. The standard drug is acctazoleamide,
which is distributed under the brand name
Oiamox, Krasney explained. Ir works well if taken
four to five days before going ro a high altitude,
and helps to a variable extent after symproms have
developed.
"No one has any idea how Oiamox works; he
added.
Another drug, a steroid called dexamethosone,
can also be effective when used prophylaccically.
The problem with dexamethosone is chat if you lose
your pills or stop raking chem, the symptoms of
acute mountain sickness can be amplified in a nasty
way.
How these drugs work and what ocher therapies
could he useful are other areas the UB researchers
wane to investigate.
"Clearly, anything we develop here is going to
have tremendous benefits for people with lung
disease who suffer from oxygen lack at sea level;
Krasney said.

BL,FFALD PHYSICIAJ\. A1'D BIOMEDICAL SCIE:-..TJST

..

�TMIS

KINOOF

RESEARCH
FALLS

UNCER

A BRANCH

OF

MEDICINE

..

CALLEO
'MOUNTAIN
MEOICINEt
THAT
ONLY
FIVE

YEARS
CLO.

his kind of research falls under a branch
of medicine called "mountain medicine"
chat's only about five years old, Krasney
said. It looks ac physiological problems caused by
high altitude.
Krasney performed his research with Douglas
Curran-Everett, who was a Ph.D. student at UB and
is now at the University of Colorado, and Jun
Iwamoto, M.D., Ph.D., a Japanese neonatologisc
who is working at UB on a Buswell Fellowship.
Iwamoto is from the University of Occupational
and Environmental Health in Kitakyushu, which
has become one of UB's sister institutions.
The reseachers conducted a fairly simple experiment.
Sheep were placed in a low-oxygen chamber for
four days, which produces the effects of being at
high altitude - comparable to about 15,000feet.
The real stress of being at high altitudes is the lack
of oxygen, not the low pressure, Krasney believes,
so using a cumbersome low-pressure chamber with
air locks isn't necessary.
This experiment lasted much longer than those
conducted by ocher researchers which subjected
animals or people to low oxygen levels for only an
hour or two. The longer time span enabled the UB
researchers to better follow che course of the
sickness, which generally cakes a few hours co
develop, Krasney noted.
In the experiment, the researchers used
radiolabeled microsphercs - tiny plastic beads only IS microns in diameter. These beads were injected into the left ventricle of the sheep's heart
where they mixed with the blood and were
d1stributec.l throughout the body in proportion to

[i

BvFFALO PHYSICIAN AND BIOMEDICAL SCIEl'-'TlST

IS

ABOUT

the blood flow. This is a very high-resolution indicator of the blood flow co a region, in this case,
the brain.
"In fact, radiolabeled microsphem, have become
the 'gold standard' for the measurement of cerebral
blood flow,"Krasney explained. "This is the method
against which everybody judges the more indirect
clinical methods."
After four days, the sheep brain was removed
and studied. The researchers found signs of cerebral
edema.
"It appears that edema 1smore prominent in the
white matter, but we don't know why; Krasney
added.
Now that they've studied high altitude cerebral
edema, the investigators plan to look at the related
problem of high altitude pulmonary edema, where
the lung tissue fills with water.
The UB researchers also plan to continue collaborations with researcher,. in other parts of the
country. They've worked with a group of Army per·
sonnel at Triplcr Medical Center in Hawaii who
have a lab at 14,000feet on Mauna Kea, an extinct
volcano that offers the only snow skiing in Hawaii.
The Army is interested in acute mountain
sickness because when two armies are fighting at
high altitudes, the one that gets acute mountain
sickness is the one that loses, Krasney pointed out.
Much of the clinical data we have today came from
the 1967 Indian-Chinese War. The sickness
devastated the Chinese Army during battles in
Tiber.
Krasney also has startcJ a collaboration with
Peter Hackett, M.D., of Anchorage. An emergency critical care physician and a mountain climber,
Hackett was one of the two physicians who attained the summit of Mount Everest in 1981with
the American Medical Research Expedition.
Hackett has established a laboratory at 14,000
feet on the west buttress of Mount McKinley or Denali, which they prefer to call it.
"It's probably one of the more hostile environments on che planer;• Krasney noted.
Crevasses suddenly open up and people disappear.
Hackett and his colleagues have sec up an
emergency aid station during the climbing season.
Climbing has become so popular, probably 1,000
climbers a year try to get to the summit. A great
number will get quite ill and have to be treated or
evacuated. They've been able to try some innovative
therapies - the climbers are not only ill, but they
make very useful research subjects, Krasney pointed
out.
Control stuJics done at sea level in Buffalo will

AUTUMN l'l!N

13

�be coupled with high-altitude studies on Denali,
1-l which has a very well equipped laboratory.

This winter, Krasney will cake a course in ice
climbing and winter mountaineering in order co
go up on the mountain himself.
"My interest is co work with the human patients
who are suffering from acute mountain sickness and
high altitude cerebral edema. I wane to gee some
further insights co cake back co the laboratory and
attempt to work out the more fundamental issues
in experimental animals," Krasney said.
"Ir's a nice example of how we can go back and
forth from the experimental animal laboratory to
the field situation where people arc actually suffering."
•

Environmental
Research
Unites
The Several
Disciplines
in Physiology

//'An

interest in abnormal environments
unites the different disciplines in the
Department of Physiology," said Leon
Farhi, M.D., distinguished professor and chairman
of physiology. "Environmental research has always
been the core of the department."
The researchers wane to know how biological
systems reacr co extremes in gravity, temperature,
air pressure, and gas density.
This research is applied to a wide range of interests, including circulatory and lung disease in
newborns, space travel, and deep sea diving.
The work goes back co World War II and the
respiratory studies of Hermann Rahn, distinguished professor of physiology who is known as
one of the fathers of aerospace medicine. He and
his colleagues clamped themselves into low-pressure
chambers to conduce experiments that had direct
application to fighter pilots.
"Almost the entire subject of respiratory
physiology came out of chose very early studies,"
noted John Krasney, Ph.D., professor of physiology
at UB. "So, in a way, we're still studying things that
Dr. Rahn began investigating 40 years ago."
In the 1960s, UB was selecred as the site for a
federal center of excellence in special environments.
The government decided to set up a number of
these centers in varied fields such as biology,
linguistics, and mathematics. Ir grew out of a desire
co enhance the country's research potential in case
of an emergency, said Farhi.
The government had learned a lesson during

AUTUM:--:198Q

World War 11,he explained. When the military had
co land troops in North Africa, it was discovered
that nobody knew how the desert affects humans,
nor did anyone know where to find the experts who
could study the problem.
The centers of excellence were set up with no
specific mission - they would simply be available
if needed.
Teamwork was co be a key element of the centers
and UB had already assembled experts in altitude
and gravity, temperature regulation, diving, and
other fields.
With the center "we got a nice pot of money
for equipment," Farhi added. "It paid for the big

BLiFFALOPHYSICIA:&gt;:A:&gt;:DBIOMEDICALSCIE:&gt;:TIST

�ments ar UB came in 1985 when rhe University
established an interdisciplinary research center.
The Center for Research in Special Environments serves as a resource for researchers in
academia and industry who need equipment,
technical support, and access ro scientists in environmental physiology and human engineering,
explained Claes Lundgren, M.D., Ph.D., professor
of physiology and director of the center.
"Imagine how difficult it would be if a researcher needed to conduct an experiment with a highgravity load and didn't have rhe equipment," said
Lundgren.
Nor many agencies are willing ro give a grant
for a $5 million centrifuge or a $2.5 million pressure
chamber, he noted. And who would have the rime
co plan and build rhe equipment, then hire and
train personnel?
"We're here and available; Lundgren said.
The maker of a diagnostic device for eye disease
is one company that took advantage of the center's
services. It had to test the device to ensure it would
function at high altitudes, such as in Denver.
The center is working on several projects for the
aerospace industry, Lundgren said. It's looking at
ways to protect crews against high-gravity loads,
such as when a plane makes a sharp turn. Another
project looks at the body's reaction to explosive
decompression, which could occur when a cargo
door blows off.
Still another project with local industry involves
a mathematical model for a pressure regulator valve
that has applications for pilots.
Other experiments examine ways to prevent
.....decompression sickness, better known as "the
bends;" how to swim using a minimum of energy,
and how to build a better breathing apparatus for
§it use underwater or in hostile gaseous environments.
To aid this research, UB's equipment has been
improved, Lundgren noted.
The deans of the schools of medicine and
engineering gave a $250,000 grant for a technical
upgrading of the saturation diving system that
allows people to live in the pressure chamber for
extended periods.
Through a grant from the medical school, the
pool was clad with stainless steel to reduce upkeep.
An upgrading of the human centrifuge from a
capability of 7G to 9G or more is expected to be
completed this fall.
"There have been a lot of improvements to the
equipment, reflecting the commitment of the
University to this unique facility; Lundgren noted.•

I
j
pressure chamber, the human centrifuge, the swimming tank, and lots of lab equipment."
The equipment is housed in the Hermann Rahn
Laboratory on UB's South Campus.
Once the government provided the equipment,
the researchers were on their own to support their
research. They've gotten grants from NASA, the
Air Force, the Navy, and the National lnstitures
of Health. (No classified research may be done at
UB.)
As well as lab work, field expeditions have been
conducted underwater in Korea and Australia, as
well as high on mountaintops in the Alps.
Another boost to the study of special environ-

BL'FFALO PHYSICIAN Als:D BIOMEDICAL SCIENTIST

CLAES
LUNDGREN
DIRECTOR
THE
FOR

IS
CF

CENTER
RESEARCH

IN

SPECIAL

ENVIRON­
MENTS.

-B,

Connie Oswald Scofko

AUTUMN

1989

15

�'

l6

~Y
lonni~
~~wal~
~rntko
he scientific community must
band together and convey this
message to the public: we're not
hurting animals, we're saving
human lives.
That was one of the points
brought out during a day-long
$UNY-wide conference on animal rights held at UB in June.
The conference was attended
by public relations staff, researchers, veterinarians, and administrators from several SUNY
campuses and Buffalo hospitals.
John Deats, director of public relations
at New York University, told the group
that when one researcher at NYU was
targeted in protest by an animal rights
group, the whole university got involved with the matter.
At NYU, "we developed a consensus
among the faculty: no researcher can
stand alone," he said.
Deats also emphasized that universities
must open their labs - not to animal
rights activists, but to representatives of
the public, that is, to the media.
That suggestion was echoed by
Charles (Bud) Middleton, director of the
Division of Lab Animal Resources at
Stony Brook. It's important to show that
the animals are perceiving no pain and
that there is a compelling reason for the

~

research, he explained.
"But you can't give a partial tour," he
warned. "It has to be all or none."
The problem with opening all of the
labs is that a number of investigators
have received death threats, Middleton
noted. They fear for their safety and the
safety of their families, as well as for the
animals and University property.
At Cornell, one researcher was the
target of months of protests, said Fred
Quimby, director of the Center for
Research Animals at Cornell. One day
she received a phone call ac l a.m. in
which an unidentified caller told her char
if she didn't drop her research with cats,
he would kill her children and kill her.
The next morning she dropped her
work.
Cornell wants to make sure that
doesn't happen to one of its researchers
again, Quimby said. It has developed a
"proactive" faculty committee to stress
che point that animal research has greatly benefited both human and animal
health. The panel involves representatives from research, teaching, wildlife
conservation, and agriculture.
"I think this lies at the crux of what
we all have to do," he said. "The time of
looking at che issues as they relate to our
use of animals, with a narrow focus on

•
AUTUMN 1989

BL'FFALOPHYSICIA:-S
A),.;DBIOMEDICALSCIE:-.:TIST

�-

~
Q

z

0

::E

vi

17

§
.i

Charles (Bud)
Middleton,
director of
the Division
of Lab
Animal
Resources at
Stony Brook,
says that it's
important to
show that the
animals are
perceiving no
pain and that
there is a
compelling
reason for
the research.

education or research is over.
"Standing alone is the way that we're
going to be split up and the way that
eventually we'll lose this battle. I, for one,
feel that we all have the same vested interest and we're all going to approach this
in a solidified manner."
SUNY is bringing its researchers and
administrators together through a new

committee on animal research.
The purpose of the committee is to
share i,deas among campuses on how to
protect' the welfare of animals and how
to conform to rapidly changing State and
federal regulations.
One mission of the committee will be
to tell the researchers' side of the story
- how animal research helps human

BUFFALOPHYSICIAN AND BIOMEDIC AL SCIE:S:TI
ST

welfare.
"We're all interested in animal welfare,
but that's different than animal rights;
explained SUNY Provost Joseph C.
Burke. "Animal rights, if carried to an extreme, would make it difficult or impossible to conduct research on animals.
Neither our society nor our University
can accept that."
•

AUTCMN JQS9

�Medical Scudencs

18

From Rags to Stitches
John Border gives a history of trauma care

By DAVID M. SNYDERMAN
.000-year-old
.
mummy was discovered
vith an open fracture (where both
km and bone are broken). John
~
Border, M.D., pointed out that there were no
signs of healing and rhm rhe broken femur
was the cause of death.
"This is an ancient problem; explained
Border, an expert in trauma care. "The results
of trauma care were absolutely dreadful. The
mortality rate for any significant injury
(penetrating wounds of abdomen or chest, or
open fracture of the femur) was 50 to 80 per
cent. Those who did survhe were permanently disabled.
"This began to change for open fractures
!are in World War I but did not change for
other injuries until the mid '4(}.; and early '50,.
"Since rhen the results of care have progressively improved as our knowledge of rhe
basic sciences of physiology, biochemistry,
and cell biology has improved."
Border is a professor of surgery and orthopaedics and a research professor of
biophysics at UB. As the recipient of la,t
year's Stockton Kimball Award, he delivered
the 1989 Stockton Kimball Lecture ac rhe annual faculty meeting this spring.
He acquainted his audience with ~ome of
the historical developments in trauma care.
Border knows of these improvements firsthand because he has played a large role in
developing them.
The methods that Border has pioneered
have decreased mortalitv rate, length of
hospital stays, and the amount of permanent
disability in patients treated in this manner.
Referred ro as •one of the fathers of modern
trauma surgery," Border is an advocate of aggressive treatment of trauma patients, which
includes performing surgery immediately.

AUTl.'M1': 198&lt;1

"Ir is quite clear that our old belief that rhe average of 1,819 days; Border said. In addipatient was too sick to he operated on the
tion, "70-100per cent had some degree of pernight of the inJury was wrong; Border noted.
manent disability and 20 per cent of these
"Such patients get sicker with the passage of were so disabled they never worked again."
Today, a simple femur fracture usually
rime. They do not get better. They need comcauses three to six months of lose \\'Ork and
plete surgical care the night of the injury to
help them get rapidly better."
no significant permanent disability.
Border, who is the director of the trauma
"This is a dramatic reduction m time even
service at Enc Countv Medical Center
from rhe '60s and '70s; according ro Border.
(ECMC), reccntlv received the Roswell Park
owever, as damaging as \\'Ounds were to
Medal from rhe Buffalo Surgical Society and
soldiers, there was a \\'Orse enemy stalkwas honored by ECMC for his contributions
mg the fighters on the field of battle.
co trauma care.
"The major problem, in all armies, was nor
Border drew the material for hi, lecture
death from wounds," Border explained. "The
from his new book titled Blum :--111/tiplemaJor problem was dcarh from disease. For
Trauma: Comprehensite Paihoph,·s1olog;;
and every soldier in rhe American Civil War who
Care.Ir is a guide ro the understanding and died of wounds, cwo died of disease. These
treatment of blunt multiple trauma cases, for were communicable diseases of childhood, rhe
instance, auto accidents.
diseases of filth, and problems such as

H

Border said that for hundreds of years up
through part of World War I, open fractures
were treated by amputation.
In fact, the army field hospitals "were usually marked by huge piles of amputated limbs
and dead bodies." As a result, he said, rhc
hospitals "were usually quite easy to find."
The amputations \\'ere performed in under
three mmuces and required up ro six strong
men to restrain the patient.
The military surgt.'OnDominique-Jean Larrey "at the Barrie of Borodino did 200 amputations m 24 hours," Border noted.
\Vhen patients managed co keep borh their
li\'es and limbs, "they lost years our of work"
and , for the most part, "were permanenrlv
and severe!y disabled; he said.
"According to Lorenz Bohler (a modern
surgeon who "'as an expert m the treatment
of fractures), prior to World War I a simple
femur fracture kept you out of work an

malaria."
In fact, it was nor until World War I that
disease and wounds had similar mortality
rates and not until World War II that wounds
passed disease as a cause of death.
"These ad\'ances depended on vaccination,
~anitation, and antibiorics," he said.
Border remarked that poor sanitary practices of the day horh in and our of the
hospital helped co aggra\'ate the disease
situation.
Sanitation was, m fact, one of the primary
problems of medical care until rh1s century,
Border said. Wounds were washed \\'ith pieces
of non-sterile doth rinsed in a communal "pus
bucker."
"These rags came from an international rag
marker, or were discarded linens; Border explained. "They were later found co be a major carrier of bacterial disease from place to
place."

BL'FFAI.OPHYSICIA:&gt;.A:S:DBIO~IEDICALSCIE:S:TIST

�Medical Students

19

Conditions in the operanng room were little better, Border said, giving the example of
a Viennese surgeon from the last century.
"This is Theodor Billroth operating in Vienna," Border said, explaining a particular shde.
"Notice no hats, no gowns, no gloves. The
huge audience is breaching on the wound."
Many of the improvements in sanicac1on
can be traced co Florence Nightingale's reform
of hospitals during the last half of che 19th
century.
The care during the Crimean War was so
bad and so well publicized that the Briti,h
government hired a group of young women
to go with Nightingale - these were the fir,c
paid nurses.
The mortality rate at the hospital where
Nightingale worked during the war dropped
from -l2 per cent before she arrived to 2 per
cent while she was there. She later repeated
thb performance at a second hospital.
As a result, Border said, Nightingale is
credited as the founder of nursing as a profession.
One of her decisions, although seeminglv
simple, was extremely important.
"An absolutely valuable change here,"
Border said, "was doing the laundry with hoc
water. It was not until much later that ic was
proved that laundry with cold water did not
change the bacterial content at all, whereas
laundry with hot water did."
Another
invaluable
change
that
Nightingale made ro patient care was an insistence on accurate patient records and
statistical summanes of the patient care.
"One has to give her credit for creating
modern scientifk medicine," Border concluded. "Pnor to Florence Nightingale there were
no hospital records."

0

ne of the next great advances in surgery
and patient care, Border said, was the
use of anesthesia.
Anesthesia entered the scene in 1846. "Bue
no doctors could make a living ac it, so there
were very few doctors who gave anesthesia,
and the tradition was chat the surgeon
called on whatever docror walked down the
hall; Border said. "No measurements were
made of vital signs or blood loss and no intravenous fluids were given during surgery.

try of both toxins and bacteria? This is an
enormous change in viewpoint. Granted, the
basic hiology involvL-dapplies co most ~ritically ill patients and not just to the trauma patient."

The care of trauma patients, Border said,
has improved "primarily because of a large
amount of basic science research, which
allows us co understand metabolism, cardiopulmonary physiology, the whole thing
that goes wrong with the trauma patient."

Florence Nightingale: she improt·ed
hospital sanitation.
"There was no real professional anesthesia
until World War II. At chat time, the armb
trained and designated anesthetists.
"There was another very important change
at chis time and chat is that the anesthetiM
should nor only be an echcrizer buc a
rcsuscicacionisc; he noted. "This required an
enormous development in biochemistry and
physiology to know whar to do.
"John D. Stewart, a former professor and
chairman at the department of surgery, made
the major contribution co chis advance."
The latest and probably greate&lt;\Cadvance
in trauma care i, the realization that we were
looking at the problem of infection complccely wrong, Border said.
To fight infection, stronger and more
numerous antibiotics were used. Bue because
che critical illness and infections came from
toxins and bacteria in the gut, annbiotics actually encouraged infection by destroying
beneficial bacteria which kept detrimental
bacteria in check. This allowed the detrimen•
cal bacteria to multiply and enter the rest of
the body.
"The annbiotics we administered to treat
infection undoubtedly caused infection; explained Border.
"The correct way of looking at chis problem
is undoubtedly, how do we support growth
of the good bacteria in the gut and how do
we support the gut mucosa as a barrier to en•

BI.JFl'Al.O PHYSICIAN AJ\:D BIOMEDICAL 5CIENTIST

Despite public belief to the contrary, Border
said, the total cost of health care has accually gone down because modern medical care
has been able to get people on their feet and
hack to work sooner. This has more than offset increased hospital and doLtor bills.
"You have to understand chat, of rhc total
cost of accidental injuries today, only some
place between 13 and 15 per cent goe,, for doctor and hospital bills; he said. "Eighty-five per
cent of the cost is in temporary and permanent disability and death.
"Of this, the dominant portion is temporary
or permanent disability. This is where the real
cost is."
He explained that the net effect of all
changes in modern care has been to shift coses
from the disability/death category inro the
hospital care dassiftcation.
"The per diem cost has gone up even more
rapidly because of the reduction in the length
of hospital stay," Border ~aid. "This trend
began in the '40s because it resulted in better care. John D. Stewart also contributed to
thb advance.
"Unfortunately," he continued, "our political
leaders look only at hospital costs and do not
look at rhe effect of the changes in care
(reflected in hospital coses) on the length of
temporary disability, the numbers of cases,
and degree of permanent disablity or the mortality rate both in and out of the hospital.
"The essence of all changes in modern care
that have occurred has been to reduce outof-hospital costs by increasing hospital coses~
A, a result, he concluded, the total cost of
health care, when both hospital and ouc-ofhospical costs are caken into account, has
"dramatically" decreased "in total coses for
many dbease problems, including trauma."•

AUTUMN

191!9

�Medical Students

20

\
J

THEHEADBONEIS
CONNECTED
TO. . .

F

or the 143rd time, the University at Buffalo School of Medicine and Biomedical
Sciences has injected new physicians
into the practice of medicine.
On May 21, during a ceremony held in
Alumni Arena on the University's North
(Amherst) Campus, 140doctor of medicine
degrees were conferred, along with 26 Ph.D.s,
and six master's degrees.
As proud parents and families looked on,
the new doctors strolled down the aisle to
receive their hoods and diplomas in a
ceremony that featured vocal music hv the
0ermatones, an a cappella group of medical
students.
John Naughton, vice president for clinical
affairs and dean of the medical school, commended the graduate, for the concern they
showed for a classmate, John Robin, who contracted cancer during the sophomore year and
died in September of 1987. The medical
students memorialized Robin in their yearbook, the Iris.
Robin's untimely death, Naughton said,
"was a tragedy that we all felt," and the medical students' compassion toward their classmate "shows that you are ready to become
physicians."
The class speaker, Paul Lccat, looked back
on the four years the new physitians had
spent together.
"As I look around the room, I can only
think of one four-lccter word that I picked up
in New Orleans to describe all of you, and
chat is 'fine;" Lccat said.
The 1989 yearbook, che Iris, was dedicated
co the art of medicine. Loriann Fraas and
Diane C1cacel10,co-editors, presented a copy
of the yearbook to Lilh Sentz, history of
medicine librarian.

C

ommencement speaker Harry L. Metcalf,
M.D., former president of the AmerJCan
Academy of Family Physicians and associate
clinical professor of family medicine, warned
students who were leaving Buffalo that "in
about two months you will have acute

withdrawal symptoms for chicken wings and
Bocce pizza."
On a more serious note, he left the class
with three things to remember.
"First and foremost, you owe a very large
deht of gratitude to your parents and family,"Metcalf said. "J\.:evcrforget char many years
of struggle, support, and sacrifice went into
allowing you to realize your dream."
He also urged graduate, to support their
medical school and to live up to their responsihilities to help their communities.
"\'('hen you arc setrled into your career, give
something back to the community in which
you serve," he urged. "Participate in your
specialty organizanons, the PTA, your church
or ,ynagogue, or whatever charitable way you
&lt;:hoose. But please, don't he Just a taker~
He concluded with a short anatomy lesson.
"There's one more thing you can learn
about the body that only a non-doctor would
cell vou; Metcalf said. "I hope you'll always
remember this: The head bone is connected
to the heart bone and don't let them come
apart."
•

BlJFFALD PHYSICIAN AND BIOMEDICAL SCIE:S:TJST

�Medical Students

\

J

BlJFFALO PHYSICIA~ AND BIOMEDICAL SCIENTIST

AUTUMN 1989

�Medical Students

22

Pull Out All the Stops
Go as Far as Possiblein Treating Patients,
Advises Noted Pediatric Neurosurgeon

By DAVID M. SNYDERMAN

P

ediatric surgeons who work with brain
damaged and potentially brain damaged children face difficult ethical
problems, Benjamin Carson, M.D., told a
group of medical students recently.
"The whole issue becomes one of how much
time do you put into the care of individuals
like chat?" he asked, advising the future doctors chat they should, wherever possible, "pull
out all the scops" in the treatment of their patients.
Ca rson, the director of pediatric neurosurgery at Johns Hopkins Medical School,
made the comments at UB May 5 in the first
annual Progress in Medicine Lecture sponsored by che Student National Medical
Associanon. Carson is known for his separation of a pair of Siamese twins.
He illustrated some of the ethical questions
confronting physicians by detailing case
histories.
"I remember a case of a young girl - four
years old - who had Ix-en hit by an ice cream
truck and suffered a very severe head injury,"
he said.
The girl was brought in over the weekend
and Carson did nor sec her until Monday
morning.
He was told chat "the only function she had
at chat point was pupillary reacrivicy."
However, when he examined her, her pupils
were fixed and dilated, implying severe head
trauma . He decided to operate.
"T-vo weeks later, she was awake, talking,
and responding co commands," Carson said

AL,TIJMl\ I98Q

Benjamin Carson, M.D., gave the first
Progress in Medicine Lecture .
with a smile. After two more weeks, "she
walked home and was neurologically normal."
Many people, he noted, would have argued
early on char surgery was a waste of resources,
chat the girl's case was hopeless , and chat it
would be best to just let her die.
"If we had done that, we would have lost
someone who was subsequemly normal," he
said.
In another, similar case, a young boy was
seriously injured and the mother wished to
pull him off che respirator. Carson talked the
woman imo allowing him to treat the boy.
"We wem ahead with it, and he subsquently
walked; the neurosurgeon said. Although the
boy did have some neurological impairments,
Carson said, che mother was oveqoyed to
have her son alive.
Then there was the case of a man injured
m a car accident . The patient was in control
of his mental faculties despite being depen-

dent upon a respirator.
"He made a request to us bv sign language
chat we disconnect the respirator and allow
him to die; Carson said.
Boch his family and clergyman accempted
to calk him out of it, "but no one could convince him otherwise. After several days we
removed che respiracor."
Thar brings up the question of what should
be done for children in similar circumstances
who do not have che experience and
know ledge co make similar requests.
"How can you make such a dc.-cision(rcmoving a respirator) for someone who hasn't experienced life?"Carson questioned. "That's
one of the biggest ethical problems."
Carson gave another case history concerning a girl who had been seen by several
cop specialists around the country . When he
saw her at Johns Hopkins, he felt surgery was
in order.
However, a well-known
neurologist
disagreed and attempted co get the hospital
to intercede to keep the girl out of surgery.
But the neurologist "then made a big mistake;
Carson said. "He went to Rome for a conference, and I realized this would be a good
time co do it."
Carson said the girl has made excellent progress, thanks to the surgery.

F

inally, Carson told of his experience in
the separation of a set of Siamese twins.
Traditionally, such twins were either left
together or one was sacnficed so the other
could live.

BUFFALO PHYSICIAN A1'D BIOMEDICAL SCIENTIST

�Medical Students

23

However, m the case of the seven-monthold twins brought to him, "the mother didn't
want to choose which one would survive and
which one would be sacrificed."
So Carson embarked on a procedure to
separate the twins in such a way that both
would be able to live.
"We thought the chances were no greater
than 50-50," he recalled.
After a grueling surgical marathon, in
which a total of 70 people were involved, the
twins were separated. During their recovery,
"they suffered just about every complication
known to man but they subsequently began
making a significant amount of progress, and
eventually went home."
The enti re action of separating and caring
for the twins cost about $2 million, Carson
said, of which the hospital paid half. But no
hospital can afford that kind of expenditure
on a regular basis.
"The way you solve that problem,' he noted,
"is you share the wealth. You don't require
one institution to perform all of these procedures."
•

Academi1cLadder; she told her audience that
it's important to set goals.
Academic promotions - the rungs of the
acaderni,c ladder - arc just benchmarks of
our succ,ess, not goals m themselves, Behrens
emphasized. We must always remember the
larger goals - helping asthmatic children or
finding a cure for cancer.
While setting goals, you can dream big
dreams, but the dreams have to be focused
through the small end of the telescope of reality, Behnms said.
You must also realize that your goals can
change. As a teen, Behrens wanted to help
with health care in Third World countries,
but didn't plan to be a dean.
She diid become a dean and her plan to
practice in the Third World was deferred,
though not abandoned. As a dean, she
facilitate:sThird \Xlorldprograms through her
school. Still, the pediatrician plans to someday practice medicine in the Third World.

Using your personal time carefully is as important as using your professional time
carefully, Behrens added.
"It took me a number of years to realize that
other people can cook and clean, but I'm the
only one who can listen to my husband and
put psychological Band-Aids on my hurting
children," Behrens said.
She also discovered that when juggling
many roles, it's easy to forget to set aside time
for one important person.
"] had left out one person - me," Behrens
said. "I was giving so much, there was nothing
left for me." She learned that she had to attend to her own emotional and spimual wellbeing before she could focus on her goals.
There's no room for coasting, Behrens
added.
"You must develop as a professional and a
person for the rest of your life,"she urged. •
B:, Connie Osu:ald Stofko

CLIMBINGTHE
ACADEMICLADDER

A

t one point m her career, she felt as
if she was living in a pressure cooker.
She was on 20 cornrnirree:sand trying
to juggle her roles as clinician, researcher,
teacher, administrator, spouse, and parent.
With so many deadlines, it was hard to get
through the day, said 8. Lyn Behrens, M.B.,
B.S. She eventually learned that prioritizing
one's goals makes it easier to say "no."
Drawing from her own experiences,
Behrens, the dean of the School of Medicine
at Lorna Linda University and one of only
three female deans of medical schools in chis
country, took parr in a four-day program on
academic achievement.
This spring's OW. Harrington Visiting Professor, Behrens is gaining a nauonal reputa•
tion for her presentations on faculty
development.
As part of a session on "Climbing th c

B. Lyn Behrens,

BUFFALO PHYSICIAN A:-.:D B10:l.1ED!CAL SCIE:-.:TJST

one of only three female med school deans in the U.S.

AUn..:M:-.: 1'189

�,.
Medical Students

24

OUTSTANDING
FACULTY
HONORED
AT
ANNUAL
MEETING

T

he 1989 Annual Faculty Meeting
witnessed the presentation of many
awards for teachmg excellence, research, and service to the school and communitv.
This year's Stockton Kimball Award for excellence in academic achievement was given
to Saxon Graham, Ph.D., who will deliver
next year's Stockton Kimball Lecture.
Graham, an epidemiologbt, is a preeminent
member and chair of the Department of
Social and Preventive ML'Clicine.His work has
been primarily m linking diet to various
diseases and suggesting dietary modifications
ro help prevent the onset of these maladies.
His best known qud1es involve colon and
breast cancers . Graham has linked dietary fats
ro a high risk of cancer of the colon, lung,
and stomach. Equally important, he has
reported a potential protective effect of
carotene in combatting cancers of the mouth,
lung, esophagus, and stomach.
Graham has also suggested that women
who arc m high-risk categories for breast
cancer limit their alcoho l mtake.
This year's Stockton Kimball Lecture was
delivered by John Border, who 1sprofessor of
surgery and orthopaedics and a research professor of biophysics at UB, as well as director
of the trauma service at Eric County ML-dical
Center (see accompall)mg amcle).
The Dean's Award was given to No rman
Solkoff, Ph.D., a probsor in the Department
of Psychiatry, for his service tO both the
medical school and the University as a whole,
and outstanding research.
Special recognition went to Murray Ettinger, professor of biochemistry, and Charles
Severin, associate professor of anatomical
sciences. Ettinger was recently named a
Distinguished Teachmg Professor by the
SUNY Board of Trustees and Severin received the Chancellor's Medal for Excellence
m Teaching.
The second annual Robert S. Berkson

AUTUM:-..'19R'I

I
Saxon Graham
Memorial Award in the Art of Medicmc was
given to Robert Reisman, clinical professor of
medicine and pediatrics. The purpose of this
award is to recognize excellence in patient care
and teaching by a volunteer faculty member.
The Louis A. and Ruth Siegel Teaching
awards, which recognize teaching excellence,
were presented in four categones:
■ Steven Gutman, M.D., assistant professor of pathology, received the Pre-Clinical
Award .
Letters of commendation were given to Edward Car r, M.D ., professor of pharmacology
and therapeutics; Perry Hogan, Ph.D ., professor of physiology; Alan Lcssc, M.D., assistant professor of pharmacology
and
therapeutics as well as medicine; Charles
Severin, Ph.D., associate professor of
anatomical sciences, and John Wright, M.D.,
chair and professor of pathology.
■ Ralph Doerr, M.D., assistant professor
of surgery, received the Clinical Award.
Letters of commendation went to Paul
Davis, M.D., professor of medicine; Margaret
Paroski, M.D., assistant professor of neurology
and physiology; Luther Robinson, M.D., assis-

tant professor of pediatrics, and lnsook Shin,
M.D., clinical assistant professor of neurology.
■ Joel Paull, M.D., clinical assistant professor of surgery, won the Volunteer Award.
A letter of commendation was awarded to
John Treanor, M.D., clinical assistant pro•
fessor of psychiatry.

■ Edward Co leman, M.D., clinical as:;istant
insrructor of surgery, was given the House
Staff and Special Award .

Letters of commendation were given to
Donna Desmone, M.D., clinical assistant instructor of medicine, and Deborah White,
M.D., clinical assistant instructor of medicine.
Also at the meeting, Nancy H. Nielsen,
M.0., Ph.D., the new president of the Medical
Society of the County of Eric, introduced
Charlene Cortese, New York State Medical
Society Auxiliary,
American
Medical
Association-Education and Research Foundation (AMA-ERF) chairperson, and Phyllis
Caputi, president of the Medical Society of
the County of Erie Auxiliary. They presented
checks totaling $8,004 to the medical school.•

- 8,· Dal•idM. Sm·derman

BUFFALO PHYSICIAN AND BIOMEDICAL SCIENTIST

..

��Medical Students

Suraj Arthur
Acharva, French
LitcralllreB .A ,
Lniwrnr) of Califonua
S.C I am mr,·rc,1edm
,ntL~uumnalmedicine,
ch,1mb..&gt;r
mu,i,, and arr

Kawh Ali:adch,
BwloJ&lt;.,
B.A.. Ctmiell
Unn-ernty. Bnrr!

Eli:abcth Ann Allen,
Trina Bernadette
B1ochcmi,1n B S ,
Allen, BwloJ?Y
B.A.,
Unit a,rr, at Buffalo. I
\' assar Colle[!.eI like
l(J(Jk
foru·ard w sf&gt;,mdmg hiking, mm ies, and
caung &lt;'hce.,ecake
cnwtht.-r
four ,·ears m
. .\led
sch,-,1fu, m /i.ruwn
Buffalo.

:--:ancv A. AllenRichard, Bi.. :hemistry
B.S , Sl';'\JYat Sum,

Brook I h,ll'e 11great
st1f&gt;f&gt;or111
c Jamily and

Jewel Damita Alleyne,
Bwchcmmry, Hof,1ra. I
like w ,mg, I lo,e w
tratel. I chose lJB
becauseof the re.,earch.

I'm gladw Ii. m
Buffalo.

hmm,.

Matthe,- Evan Alt.,,,
Chcmisrr, B A., \eu
YorkL'nn-ernry I cho,e
l'B bern111eof rhewe,11
Rmh:·rs.

Elvs,a Anne
Blissenbach, Bwk,J&lt;.,
B \ , Fairfidd
L nn ,'TS1fy.,\h jat&lt;&gt;me
pasume" figure ,karmf!..

Gre~ory A. Andre",,
Got&lt;"Tltmenr A.

B,

Michael Jo,eph
Aronica, Bwlos::,B.A.,

Harmrd L'nm:rsuy. I
cho,e L'B med sch(J(JI
h.!causc!
of Its ow,tand1111!
rcpuumon

Uml'L'T'ilt)· of Rochl!stc:r.
Mike "a t,prcal med
srudcnru-hoha1cs
l1brarr.:.1
and Ime, w
parry

Renier Jo,eph
Brcntjcn,, / fowry
B A., Darnison

Jon Michael Bruce,
Bwlogy BS. Chemmry
B.S , L'nin&gt;rm:,at
Buffalo and ,'\Jia[!.ara
Una·er,11y.Hello
B11ffal11!

Colle[!.,'.1 um born ,n
Ams1erd,1m,The
Nethc'Tland.,.
and like
\(lllmf!.,

Behnam A,~harian,
B10.:hcm111nB &lt;;_,
L'n11m1t)·at Buffalo I
look foru·ard w med
schml and cnio:,,/i.mf!.a1
L'B

Andre" Jacob Bam,r,
Bu&gt;&lt;:h,·mNry
B A.,

Thoma, Gerard
Burke, Mc&lt;·hamcal
EnRtneeringB S., Notre
Dame Ir's fun to come
homefor schoolm rhe,c

Crai~ H. Burrow,,
B.,,r,,!?Y
B.S . Ho11ghton
Collt&gt;gc.I enim the an
of pantomime

curmu_, ume.o;.

Carolvn L. Be""1te,
Bioloi:yB.A ,
Camsrm Collef!.e.I &lt;1lsc, Unnc'TSII)of Roche,ier.
lune degreesm la1t•,
Lookmgfonmrd to
music, d..'!lusrry,and
medicalsch,.,I. Enj&lt;&gt;y
elecm.:alengmeenng.
playm,irhe1·1olmand
cycling.

Heather R. Campbell,
Bioloi:yB.S, Cornell
L'n11ernr,.I like being
uurdoon and bakmgnut necessonl~
· m the
~me ume.

�Medical Students

Rodnn Cap,ro,
P,:«·ho/og,B A , Xcu

r,,rk Um1s'T"':·
Becominga ph,.\lcklll
has /&gt;.:ena lifelong
ambmun.

Ann" Mari" Comi,
B,o/og, B.A . f/oly
Cm". I reallyrhmk
the.,t!qut.1.,rlmt,an.•
ab,urd so I'll JIN keep
:mu folksgun\lng

Li,a Ann Cardamone,
810l01?:B A .
Lrmh·nil'\ vfRo,·hesct:r
I am tloconh a sc:,:unJ.
gencrarum 1&gt;h,"c1&lt;1n
/,ur
aho a u·c,i:htl,frcr.

Andre" C. Cor,dlo,
Chcm1Srry13.A..
C,m1dl L'1mernr, I
,d\11hatc J,·,grccs111ltm·
and m1Nc. I mincedw
round offm~-c.•Jucawm

I,:.gomg co mcd1,,1I
"h,.,I.

T ridJ L. Ei~~n..,tctn,
John Alt,xander D:ik,
,\1cchamcalEng111ccr111Jl 81mndK&lt;1lEn.~anccrmg

13.S.. L'n11crnr,lH
Buffalo. I cnJm pki,ml!
ra,:q1«1ball
anJ bmdmg.

B.S E Duk,·
l 1m a&lt;1r,. I l,ke w f),
/&gt;kmc,- I'm a ,ucdcnr

1,1101.

\!aria T er1!,a
Cartai:cna, B,olog,
ll S. L'mwrsit) at
Buffalo. 11,,w dorhc,

Richard Mark
Chcmdli, Bwlog,
B.A, Comdl
Unn•c.&gt;f\!l'.''·
h\ nnr JU\(
ll pro/1.!s,1,m.
1t', cm

Elaine Hee-Young
Ch,.,on, lliolo.~",md
~,..-1e1,B -\,. C,,rndl
l '1111
&lt;"T\11\ 11,ke ,kuni:
and 101111\.

William F. Chlo,ta,
Biulo.~"B S Ca.,.:
\\.'t'.Slt."ntRc:,c..'n
1..:
l Hll'~T\ll),' I ~1110:
,k11ni:.,,ulmi:, remm,
,md&lt;1rt.I'm l,x,kmg
fi,rn ,ird ro m,·d,ch,x,I

\1ichacl La" rencc
DuBartcll, Bwlogy
13.A , l 'nn,'T\lt, at
/l11ffa/u.A/1,:r
_gr,id11a11011
I 1m111Jl,k.:
10 praruct.'
/1..uml)
m,:Jii.-mc.·.

Karen M. Dui:uid,

(1t.lt·i:1UUTt.."

\'ane"a

L. Crother,,

Win,ton G. Oou1,:la,,

Cherm,rn and

llw,:hcnmrn 13~-,

l',y,hology ll .A ,

l 'nn.:rnl\ of Ro,hc,r,'T
I U.dtU to ht!-u doctor,o
/'II h,:,,bk w (rttm~,:
healthfare m necd.:d.

Ru/,..-rr,\\'.'csle,an
(•oil..:~.:.Fmu ~\'t.'&lt;ir,
/rom
nou I hope w/,..-&lt;1

ph,"cr,m.

Julene Op1al,.,neE,an,,
,\ f ,rr.,/&gt;wl,J!i:'.'
/l S.
Cumdl L'mwrnr, I
,ho,c L B hl?f,111,c
I
urn,IJlike w twrk j,,r
ih,· \\'.'orlJ I kalrh

Gil Michael Farka,h,
Hu._hemhtn B-~.,
L nn cT\11\ dl llujji,lo I

( &gt;r.s,:c1rn,aw,111
m Kl'n)·a

n.·r~·~.,cm:Jahuut
,mendingm.:di.al,,hwl
&lt;II LB.

,,nnc:dtl\·

c.'HJO)'
,1 Jnt."nH, oj ,pc,rb
md,«Jml!1cmm, ,kun)(.
andu:orklll,1!out I ,m1

Paul Jo,eph Fa,orito,
P"chohwlol!", H,mulwn
Coll,:g,· I um ,:a~erlo
hcgmmed ,, h,.,1 and I
hk.:m pl," ,..,,w,h

\ kd1,11ITe(hn,,/o~"
13S l '1111,·Nryof
\ l1,h1ga11.
I ,un &lt;1
&lt;'&lt;Yllfi.:d
Sign kmi:11,1~,:
m1t:rt&gt;r1.'rc.·r.
I Cdn r U.'(UI
10 ,wn !

Ilana L. Fcincrman,
B,,..-h,·m"'" 13.S
l"nn.:rnr, ,u B11/f&lt;1lo.
I
thmk 13ujf&lt;1lo
" " ~.,..:,u
pla..·c&lt;111&lt;/Im 11/,ul111/,,_,
bt,,kJi,rfour mor,:
)'t?(JT\,

�Medical Students

\1ich,,cl '-cott

D,1\IJ K. he,,

Bio!oi:y

B.S . L'nu ernry ar
Buffalo. I'm an early
assurance mukm. I'm
from N ia1;araFailsand
enJO)golf

Orn·ego I chose Buffalo
~cau..\l'of ns gtc!at
weather.

Gloria \1.
Gladk,m,ki, Bwlol(Y
B A., L'nii·,.,._m::,,ai
Buffalo. I trnrkcd in a
hmp,caiJoreight :,cars as
a medicalsecretllr. and
nou am dum)(ini:role,.

'-.indr., \I. Gutierre:,

Timoth, Danah,
H·,ln, Chemmr. BS.,

Honora \f. Heffner,
En1;!i,hB.A , Colgac.t

St. Lawrence
Lnu·,.,._my.I'm ured.•

l,'mtt'l'SII). / «ill he a
ihirdgmaarwn

Fl·r ~U..,llO,

810ch1;.~mrscry,'
B.S.. SL,\ Y ac

Biochenmcr:,B.A..
Neu York Un1tcrnry I
pia, the drnm sec. I I,ke
compwer \Clenc~, and l
u,li bea firn gcnt'l'amm
phys1cu111

ph::,,s,c1an
and I like w
piay ciannet.

Charle, R. Gr.w,
Health SciencesB S ..

Beu, B. Grc~oirc,
Speechand Drama,

K1thl~cn T. Grimm,
Canis,us,/Y}'mm!k. I

lJnncNI) at Buffalo. I
am final/:,a firn,ycar
med suukm

SL \IY at Gt&gt;neseo./
ha,, a ma.,1ds m library

haw a B S. m med wch
and aL,oa BS;-..

Jame, \I. hernia,
B11smess;&lt;v1an,1J?emcnr
B.S, Cornell
L'nn-asuy Fr,mhali
mJ11nesfurcedme to be
the paucm. Nou I i:ct to
,~«! tht&gt;accwnjrom Ute!

Wallace E. John,on,
Philosophyand Theatre
B A. , Yale. I look
foruard to leamin.~

~cicnce,tu.•ochildrt!n.
and like w readand sail

Robm \i. """•
Psycho!oi:yB A ,

Varonouch. Phowwaphy
and owd,.,r s[&gt;&lt;ms

ahaw B11ffab,.

mht.,."ck.

Li,a F. Kci,her,
BwlogyB.A., Camsn,s

College.I, a capuon
ri.?all~
· nrce~.\ll~·!

Kt·vin J. Kelleher,
B,olol(YB A , Camsn1s
College. Ba.,kechali,
wlle,hall, and rcnm, arc
my font' (hueI rau!y
use

chat,wrd)

Jonathan Robert
Kemp, Brrx:hem1,cr:,

B.A , Neu· Yark
Linu ,.,.m, / u·i,h m)'
brmht'l'George u·a.,
here. PEACE.

Cath\ Kim, Biology
B.S , \1/T Llfe"
temporaryso fin~if to

the fullesc· u•,,rkhard
and piay cwn lu1rdcr:

Eli:abeth H. Kim,
Bro!ol(Y
B A . Camm"
Co/le1;eI u-ar11to be
/urch~r young!

Ricardo Alfon:o
Knight, Ph"iail

Thera{)yB.S ..
Uniwrncy at Buffalo. I
ihmk bemg a docc,,rrs
the ea,u:.~t u·a-\ to

achie,eall charI can be

�Medical Students

T cd J. Kolia,, Bwloi,"
BS. , L nn .:mi,· of
\fa:hr.i:,m I en}o)
pla:m.i:ha,keiroll.
.,occcr, anJ the pram,.

Paul \t. Ko:1,m,ki,
Bwlolt' B .A . C,mrsrus
Collei:e I u·an1 w reach

hikingrn 1hel'hrlippmes.

Brian J. Krah.ik,

Elecmcal En.i,ne&lt;.'1111
.~
BS., Comdl
L·nriern1, I like playmi:
the /nano ari,l .101.n-r,
neuh.:rof wh,.-h I' II h,a e
wne for

Da, id J. Lee, Biolo.i::,/
.'-.·curoKrcnccB.A ..
Oh..-r/111
College I'm on

Kcuni: Wai Lee,

Kc\\•Juni: Lee,

Brochemr,1ryB.S ,
SL',\') &lt;11Hinghamwn

l\ycholo.l!)B.A.,
Comdl Uniwr,11,. I

dm«J11111.:
u hen I ,ki on

/me /&gt;kl'lll/? ,o,.-er.

lrke ,um1ming
lx1-'ke1h,II,1runnmi:.

f&gt;&lt;11d.:r

Julie A. Madcj,ki,
Bwchcm1&lt;1r.·
B. S .
l ·nrt.·Nt) at Buffalo
Can' 1 u·au w i:ei S1&lt;1rted
on rhrs1,.:11· ewurng (&gt;&lt;rrr
of m, lrfe

Karen \1. Maier, l're;\ieJ B \. . ,\' orre D&lt;1me
I Ion! l\·ntrc Durn&lt;?
{tH!lNII

Jerald Chri,tophcr
Timoth, J,1,· L,R,"a,
Kuhn, Enl!/i,h B.A ,
Biolo.l!)B.A ..
flamrlwn Collei:e I am
l 'mt ..·r,H~' of Rocht',ll'T
an attd .\liilor, ,u1dcnJo-:,.
·
I hale cmds.,&lt;1&lt;.'latl.''srn

the heaimful mnny
u·eaiherrn Bu//&lt;1/0.

appliedscrence111
hro..-he11m1r,,

Charle, Hoonjani:
Lieu, Chem1&gt;1r.B .A
Comd/ Unncrsu,

.\fohular Bro/ol:'AB ,

Tammy J. Linsner,
Chcm,,m B.A.,

Princeton L·1111c·rsr1).
I
U.'ant w Sl'rtt.' (;od ch a

Harru-rckCollq,:e I am
lookmi:f"nmrd IO med

ph,srcran.'

,chMI

Bruce B. \farshall,
Bu&lt;me,.1.\fona.11,,,nent,
Comd/ Um,crnr,. I

Ed"ard F. .\lath,
Biololt' B A., Branders

\\'.'hLnclo~!.'i orn·ntauon
..
i!nd!

Jame, Kcillh Mantc.&gt;ne,

Gina M. Marrero,

Bu&gt;&lt;:hernr.\lry
BS,

;\11crnhrol".I!)
BS,
C,mid/ L'nncrnl\ I am
/,.,km~ fonmrJ w " ,cry

SL;-,:y,11Bmi:hamron I
u'll.SIn mg r.a/iprlyrm ,1
beachrn Ca~rfomta,then
mmn and ,uul mademe
come here.

Tr.in !-Idem·
Lathrop Chcmr.m,
B.A ~l i':Y m
Brn1:h&lt;11mon

r~uardin,J.?
t' xpc:rrence
at

LB

Christina

Lc,lie Lin,

hate hem a ieach~rf,rr
four JCars I like m(),t
,f&gt;&lt;,m

Un11crn1,· I rhme w be
a ph~srcwnh.:came I
enJ") pressureand
tcn~ion

�Medical Students

Fiona A. McConnell,
Kc,·in Christopher
B1ol111;V
B A . \\:'11!1,11111Md-,,{ahon, (,oternCollege.I likehangmg
ment B.A , f-larrnrd
out I hop.:to mdke flm&lt;'
L"nlt'c..'n:lly
/"d like to
hate u praftice in
duringmed ,ch,,ol to do
sport.'i.makt.·mu~,l, anJ
Cha11ta11&lt;1ua
Count,
1omcda,.
lune fun .

frrnfe~_,ion
of medirmt.'
becau,c I lm·e 1mrk111i:

Daniel J.Mollin,
BA .
P"&lt;"hoh,,,loRY
?\'eu· Yurk L"nrtern!) . I
dcoded w i:o ro med
on /&gt;a.1r
,chwl h&lt;1,ed

u uh p.:ople.

exf&gt;t!TICUO!

Lorncllc B. Mill,,
Bwlol!)B S . ,--:cl&lt; fork
l 'n,urnr, I cho,e the

Claudia F ranee,
Michalek,, Nurnni:
B.S , D'Yrnml/e I hate
a dt.'grt!r
1n nt4rsmg.

Michael John
Naughtor,, Philosophy
B.A.. \',:'il/1am1College
I rnn ,p.:ll,\;1ct,.&lt;ehc

Andre" Charle,
Michel, Bio,:hcm"try

B.S . .\f11/m11lk
L'mn.&gt;rstt~·1tnJ'" Jly
fi.,hmg.and crm,country skiing. I look
fonrnrd to s(h&lt;H,I
.

Tuni: V. Nguyen,
Biuengmuring BS ,
L'C (II B,.,-keh I trill
he a third,i:cner&lt;1t1on
ph,sic1an.

Rogena Leonila
Miller, Bwlol!JB.A ,
Talladega I chme med
&lt;ehmlhecau.seI'm

mt,.,.e,ted111the medical
profernon and helpml(
mhcr,.

Jennifer Ann Nordby,
BiologyB.A . Corne//
L"m1,,,.1uy
. M&gt;·greatgrandfathergraduated
from UB medicalm

David A. Milling,

.s.'

B
Unn,.,..m, at Buffalo. I
PhdTTMC;i

haw a B.S m
pharman I c?nJo)
racquethalland rcnms.

Katherine Anne
O'Donnell, Bu..:hem11try B.S . SL'NYat
Bmgh.1mwn.I hate &lt;111
,\1 S m pharmacoloio.

1901!

Sanjay R., Ogra,

Biolol(;iB. ~ • Cornd1
l'mtcrnt:,. From r,,day.
1am a doctor (,umd&gt;&lt;,d)
') .
wld me rh,,r ycsterciay

Mia Pappagallo,
Bwlol()B.A P,ycholol:;i
B.A., Lnnernry of
Rochc,u:r .\1y p,mport
phoro" heucr than mi,!'

Jeffrey Richard
Parnell, Bwlo);VB S ,
L'nncr.ll!y Ill Buffalo
There" no heltercaret'l'

ch.anmed,cme!

Vikram N. Patd,
Bmchcml\lr\ B S..
SUNY at Swny BrcxJk.I
choseLB became I l,ke
huffalne.1.

�Medical Students

Frand, R. Patterson,
Bwloif.&lt;BS \1/T I
like pla)mg ,porr, and
arn,·mcs .
ocheroWlUH&gt;r

1':a"er Ra,ack,
Neurobwloif.&lt;•
Archaeoloifi·.L'nncr,u:,
of M1Chiga11
. I decu.ledw
p,o w med ,chwl m
Bufjal,, b.?rnu,eI Inc

Kri,tcn Loui,c
Paulus, B,olog, B.S ,

Come!/ L·mwn1r, I
hope clwcu e all b.?wme
chet:,·peof ph,,icum char
u·e m,ncliL', u"&lt;rnltl.
like
wgr,w .

playmg tennis, dancmg,

and oh so much more.

Jame, D. Pile, B,o!,,in
B.S., L'nrt,·rnc, m

~tichad D. Rabicc,
:\1ach13S I /ohm
Buf[&lt;lit,
. Uymnd\UC:\ ,
College So m1Khfor
children, mtd med ,,h11&lt;&gt;I math and mu,1c - on w
are 111,fllratim1al

tnl'dtclllt.'

'\'ita K. Ram,
Chcmicc1IF.ngmccrmg
8 S . t ·1111crnc,
111
Buffalo I like pl,rnnl(

t.:nni_,, cookmf!, l'atm~.

and l&gt;cmgk:,

Arlene I:. R,carJo,

:\larcu,

Med Te&lt;
·h BS . Sl ,-.;y
at Alba1n \\'.'hm I
grad,uueI 1nm1 w hate
,m officerm rn:,:,a&lt;·hrm
1heCaril&gt;ne&lt;1n
.

Romanow!&lt;.ki,

Richard

llwloi:kal E!a.sr,of
Bchmror B .A ,

Leon Ronco,
\lmhcmau.:, B A ,
'iLSY at Bmgh&lt;1111wn.
I
likeco tn.nd lo furt:11,!tl

Umtcr.,m ,,f Pcnm,ltanra I'm i:l,~Iw l&gt;cba,:k
m Buffalo. mtd mn
h,km)( Joruard to
,uu.l,mg m L'B med.

countries . I l'nJo)·
plaw11(1cnn1, und

Eric Joseph

Paul Davi ,d Seeman,

Schneider, Biology
B.A., We.deyan
Um,oermy.I enjoy the
outdoorsand athleucs.

Psychologyand Zoology
B S .. Du~• Um,oersity.
l l,ke to pla:y golf, cennis,
and j(O ,ai/i,ng.

Jeffrey A. Senall,
B10/og:,•
B A , Cams1u.s

hi:r!!

Richard Scott Safeer,
NucnuonalScience
B.S . , Camell
Unwersicy I relax by

Laura J. Pierce,
Bioloin B A ,
l ·111,
ernry ac Buffalo. I
CllJo' runruin.~and
pl,1ymgtenm, .

"'"chill

College.H,, how are ya,
mce to ,ee ya! I enjoy
sportsand lookforu:ard
to an easy four years.
Ju.stlikeei,eryonesays 11
u:,Ube, yeah. righr.

Paul Brian Ro,cnthal,
Ernnoml(\ BA ..

r

\l''
ac Bmghamwn
lott.' ro rr£ztd.tkmct.'
,
,mJ plm ,fx,m .

Mark Anthon,
Runfola, Prr/•mfr,"'"'"1/Ecrmr,m10B.A.,
.,otrr Dame . Im
h,kmg fonrnrd w
lunch.

�Medical Students

Jdfrn J. &lt;,.,ymour,
General S111d1e,
B.S..
Cornell L'mwrnry I
enJO)tl'eiihr l,frmi,
skimg, and music

Peter U-Fu Shen,
Chemi.,rry B.A..
t.:m,ernry of Chicago. I
JOI(for fun

Chri,rma Ann Smith,
BiologyB.A .. Comdl
UmH'TSU). I cho.&lt;e
UB
becau.,eI low mmhml'

Michael K. Soeder,
BiologyB.A .
lin11ern1yat Buffalo.A
pic111re
1sunrrh a
thousand,wrck

and rho,eBuffalo
beachc.,.

Andre\\ L. Sherman,

BmmessMana;:ement,
Cornell l ·111wr1it,.
Alu&lt;1yslookmgfor a
good game of balland
decent road trips.

Samiri, So,trc, Laun
Amencan L11erawreB10loi::,B.A.. Neu•
YorkU1mermy I hope
w do some mlunceer
unrk m .\iex1co.

!1-fan,our \'.
Sh1rbachch, Biochemist')

BS. CSU-Las

Angele.,. I read now ls.

Chri,tophcr D.
5prtrn I, Biochemistry
B.S, L'm«'TSII) at
Buffalo. I am concerned

for our enuronmcnt.

!min C. Srcinbcriz,

Biolo,:;;B.S . SL'NYac
Bmghamwn. I cho.&lt;e
t.:B
becauseof the lackof
sun.

Ali-sa \iaric
Shulman, Farmand
F11ncnonB.A.,
L'mwrsuy a1 Buffalo. I
am an ani&lt;1 of che
human bod:,and would
like w 111e1heseialent&lt;
m medicine.

'\; 1chola, A.
Stathopoulo,,
Bio,:hemiscryB.S .
t.:nn ,.,.&lt;It:,of Rochester.
/' m frnm Rochesterand
l,ick checreauwy w fill
rh" 1~mow

Ed"ard R.
Stcphcn,on, Bwlogy
B.A .. Fordham
lfmwrsicy. l mjoy all
rypesof spam and hope
w parucipateac l.JB.

Gail H. Smallen,
BiologyB.A.. Brandeis
L'm,ersicy. I plan w go
w Honduras. l enjoy
playing/Jureand piano.

Donna \laric Sia\\ a,:,

Bioloir.,B.S. Chemmry

s

B A. ' )1'0CIISC
L'mt·erm,. I don'r
always
l,ke 1h1s!!

1;,k

Patrkia Sticca, Bwlol(Y
B.A. Psy·choloit&gt;
B A.,
lJmwrncy· of Rochester.
l u·illbe the firn person
m my family w auend
medical school.

�Medical Students

\{i(had F. S"&lt;·cnc),
Anthmpolo,r.,,Ca,e
\l;!e,tem Re.,.:ne
L:nnersu\ . .\1d1.:n1e
,hould ~· m1cnll.ltlfJJU1I.

Roh•rt \\ . Tahara,
P,),hulo,r.,fl.A ..
l 'n11,&gt;r"I)m B11Jjalo
"' ot onl) am I a c.:rti{it:'d
,cub&lt;,,her, hm I al.",
make m) 01m ~,.,.
L,,okm!,!fomt1rdto a

Kristine L.
Tl·nchru,o, ,\.'euTl,,.
.1ocii:nl't:',
l nit't..'ntt)· of
R,x:h.:,t,:r.l lik.: to pl,_,~
tennis but most of all ,:o
01&lt;1 u·uh friend,

anJ Ii.a e

fim

\ idr, C. T ,,11,·n, Life
Science, B.S ,

L 111,ernl\ at Bu!Jalu. I
l,k,·ch..-Bill, and hope
the1 do JtN a, udl or
1-&gt;c?ucr
thi, 1..-ar

Jo-&lt;·rh S. \',1lcnti,

C,,urtcna,

Bml,,,r.,/l',~chol"J.::i
B.A . Can""" Coll~gc

Biolo.i::;B.S L urn
Colkge of \\racu,e

I hof&gt;c!
to combmt!
m)·
gncH(thwuc
rc:~c:arch
ba,kgrmmd uuh m)

,p.nt

(. ra1i:\\'.111,

rhc f&gt;&lt;Nrnu

~-l'an u:urkinRm a

mol.:rnlar /,wlo/.!)l,_,h

mt!d1calt.'ducauun

n.-tn1rdin.l?
cart..'l."T
in
rraumd sur.(!t:&gt;n·.

JuJ, ,\. \\'c,,,l,m,ki,
\ kJicin,,/ C:h.:mMn
ll S. L 1111,:rnl\ m
1311/Ja/,,.
I'm ,,amng w

Thoma, Charle,
Wh,·atlc,, BioL,~
/l A. , Cornell
L'nnc:nu~ I \.'njo)·

Chri,tophcr R.
\\'lute, Ch,·mmr)

~li,had

B.A . Add1,h,

Stmt:, Brmk I um

Ann \\',,.xi,
1310/0,r.,
B.A , C,m""''
Colle/,!&lt;'I cnJo:, trmdmg

th.:C&lt;l\) ,t11/l / l,k..B11fft1/o
u in.i:,. 1mrk,
and u.:t1th.-r

b.:gm a r,:1n1rdmg nir,:,:r

runmnJ!and am

m m1.·Jrcmt'

mh.'TC:1ilL'tf m ~diatrrC\

from SL .\'Y ,u Sr""'
Brmk.

fh,,ma, J. YJnwdla,
P"choloi,')B.A ,
L 111wrnl\ &lt;lt Buffalo I
1,k..ha,k.:1/,,.1/1.
l lun,: a
Che,.:u..-.I J,J not 11mk
th" ,wnm..-rand I h.1te
the 1'rd,, nd.:.

Atif Zaf.1r, /l1olol:)
BA . .\lath BA ,
L nnenu,· tit ll1&lt;Jfalo.
I'm " /11l,;t I .:nio:,/1/e

l na, ail,1bl,· tor
l'hot&lt;&gt;s: Paul,, A
Bcnn,·u, D,n,d ,\1
Fl\ha l,,:ojfr,·) (;.
Hoh1k.1)u,cph .\1
1'um1hk1,,mJ liu:
Ta\lor.

Jona1han I.
\\'cin,tcin.
Bu,lol!)

13..-\.,Cornell
Un11ernt)

So much for

mightbe a fl,~ht ,urgeon
at ,\'AS.-\

t ·111,crnt\ (,ra,/

de.i:rcc

E. \\ ilJ,

BwloJ.::i
B.S SL.\Y ,u

Kdh

h,kmg J,,ru,1rdw u

and tt'~t'c.m..·h I'm

cht,llcngmg careerm

excncd

medKmc.

,chool.

.,,-.,,.t
med

1t?n

��,,

•
Medical Swdent.s

25

by che UB Medical Alumni Association.
They also received a "welcome to Buffalo
package" \\'Ith maps and hints on things co
do, provided by the Medical Society of the
County of Eric.
The orientation also gi\'es the hospitals the
ability co sign the residents on co 1hc payroll
and perform pre-employment physicals .
Approximately half of the residents are
graduates of the UB medical school.
•

SCHOOL
HONORS
VOLUNTEER
FACULTY

A

reception thanking the volunteer faculty of the medical school for the
many hours thev have devoted to the
school was held May 12 in the sculpture court
of the Albright-Knox Art Gallery.
"The volunteer faculty make an extremely
important contribution ro the School of
Medicine and Biomedical SuencC!-; said John
Naughcon, dean of the school and vice president for clinical affairs.
"Historically, they've served as role models
to students and enriLhed the eJucarional experience in ways chat otherwise would not
he possible."
•

)
I

,.

0. P. JONESDIES;

WASDISTINGUISHED
PROFESSOR
OFANATOMY

ORIENTATION
EASES
RESIDENTS'
TRANSITION

E

sw-

asing rhe transition from medica.l
dent to resident is a prohlem heing
tackleJ by the UB medical school
through irs second annual resident orientation.
Two separate one-week sessions were hclJ
st;ircing June 19. Ahout I50 students parnnparcd.
One of the maJor goals of the orientation
ts to lcr the rc,idents "gee to know one
another," according to Glenda Donoghue,
M.D., director of continuing medical education anJ professional development ar UB.
The orientatton consisted of lecrure copies
caLh day with informarion char the residncts
will find u;cful throughout rhc1r rnrecrs,
Donoghue said.
lndudl-&lt;l were presentauons on organ procurement, rhc new credentialing process, the
prevention of malpralti,e, knowing rhe patients' rights, cost conrninment, and advanced cardiac life supporr.
Also presented was a program ro teach
residents how to reaLh. The first half-day
co\'cred the skill, of hedside teaching and the
second dealt w1rh the skills of evaluating.
A luncheon for the residents was sponsored

Jones received his Ph.D. from rhe Univer•
,ity ofMinne,ota m 1935 and his M.D. degree
from UB in 1956. He Joined the medical
school faculty in 1937 as an assistant professor. In 1943, he was named an associate
professor. Lacer that vear, he was promoted
co professor and chairman of the Anatomy
Department, a position he held until 1971.
He was assistant dean of the medical school
from 1946 to 1954.
Jone, wm,al,o a v1s1t111g
professor at several
institutions, including Baylor University and
National University in Mexico. In 1%4, he
was a distinguishL-d IClturer at Tulane University School of Medicine.
A member of 15 profc,,,ional societies, Jones
was program secretary of the American
Association of Anarom1sts from 1954 to 1966.
He served on the advisory councils of both
che American Society of Hematology
(1962-67) and the Continental Associatton of
Funeral and Memorial Societies (1954-1971).
He ,,·a, accive in the International Society
of Hematology, ,.:rving as its vice president
from 1958 ro 1962. He was a director of the
, ational Society of Medical Research from
1956 to 1961, and president of the Society of
Experimental Biology and Medicine, Western
New York Section, from 1951-52.
Jonl'!&lt;was assoctatc L-ditorof The A11awm1cal
R..:cord
(1955-1968),and served on the ediconal
hoards of Blood (1946-1955), and Folta
Haemawlo~1ca of Lcip:1g, Germany
(1937-1949).
The 1954 edition of Meden1ia11,
the joint
yearbook of the medirnl and dental schools,
was dedicated co him. His other honors include the 1964 Dean's Award from rhe
U111versity,and rhe l9il Silver Medal from
the medical school. He was a member of
Alpha Omega Alpha, the national medical
honor society.
He was the husband oft he late Dr. Cathryn
M. Jones. He is survived by three daughters,
Helen Jones of Maynard, Mass., Carolyn
Gurney of Asheville, N.C., and Ann Davidson of West Yarmouth, Mass.; a son, Oliver,
of Columbus, Ohio; two sisters, Ann An near
of Abs(.'(On, N.J., and Evelyn rord of Pleasantville, N.J., and IO grandchildren.
Concributions may be made to a fund to
he established in his name ar the University. •

Dr. Oliver P.Jones (M'56), di,ringuished
professor emeritus in the medical school and
a leading figure in hematology, dieJ June 18
in his home in Buffalo. He was 83.
A native of West Chester, Pa., Jones caught
gross :macomy in the medical school from
l93i until 19il, when he was named
distinguished profC!-sorof anaromy. His scientifil accomplishments were many and worldrcnowned, and his work was said to contain
rhe hcst descriptions of hone marrow
changes. He was a pioneer in the use of the
clcuron microscope in morphological studies
of blood.
"Not only were his contributions
in
teaching and research of critirnl importance~
said Harold Brody, chairman of the Deparcml'.nt of Anatomical Sciences, "but the roles
rhat he played m helping to Jevclop the
organizations and professional journals in
hematology were primary from an mtcrnanonal point of view.
"Above all, the loyalty and concern for his
students were maior facets of his c:haracter
and arc rcmemhered by graduates of the
Schoob of Med1Cine and Demiscry, as well
as hy graduate students during his years of
tenure~
During his later year, as chairman and
,tnLC
191I, Jones de\·◊ted himself co examining the early h1scorv of the medical school in
addition co the scory of its founders. These
ummbution,
,,ere published in national
journals as well a, m che Buffalo Phwcian.

BUFFALO PHYSICIAN AND BIOMEDICAL SCIENTIST

AUTUMJ\! 1989

�Alumni

26

MED SCHOOL
REUNIONCLASSES
PLEDGE
$102,220 TO UNIVERSITY

Reminiscingabout theirUB dayswas

a greatpastimefor alumni duringthe
SpringClinicalDay/ ReunionWeekend,
heldtheweekendof May 6. The alumni
not only rememberedwhat UB gave 1934 .. . . .. .......
. ... . .. . . .
From left, seated:John V. Andmon, Maria N. Samo, Charles E. May,
to them, they also took the time to and Max B. Weiner.Standing:JosephR. Saab, EarleG. Ridall, Nicholas
Linderman, John M. Constantine, and Harry Bergman.
give somethingback to the University.
This year'sreunionclassesgenerously
pledgeda total of $102,220.
Class of
Class of
Class of
Class of
Class of
Class of
Class of
Class of
Class of
Class of

AlJTUMN

1989

1939 ..........
$18,400
1944 . .... . .... $ 6,725
1949 . ... ......
$ 7,125
1954 ..........
$ 8,000
1959 ..........
$15,450
1964 ..........
$16,255
1969 ..........
$ 9,500
1939 ... . .. . .. . .......
. . .. . .
left, seated:CarlosC. Alden, William Dugan, Elizabeth Olmsted,
1974 .... . ..... $10,500 From
Ruth C. Burton, Marvin Siegel, George C. Brady, and Henry V.
Middle row: Kenneth Goldstein, John J. Squadrito,John H.
1979 . . . . . . . . . . $ 8,220 Morelewicz.
Remington,John H. Geekier,Lloyd A. Clarke, RoyE. Seibel, and Frank
T. Riforgiato.Back row: Alfred H. Dobrak, Frederic Hertzmark, James
1984 ..........
$ 2,045 ). Creighton,and A. V. Posto/off.

BUFFALD PHYSICIAN AND BIOMEDICAL SCIENTIST

•

�I

Alumni Reunion

27

1944 ......................

.

1954 ......................

.

Fromlefc,seated:L.~diafutmcain,Mrs. Strong,IdaSchaer,S)lda Ginsberg,
Charloue Fros[ Ph.llis \'(/i/kinson,Jean Boardman,~fo. Sulli,an, Mrs.
Momani, Santd M~riaCassara,Jean Bamecc,HelenHudson, Mrs. Gage,
and Ka:,,Weygandc.Standing: Mary Lou Bondi, Raymond G. Bondi,
Willard H. Boardman,Newland W. Fountain, Anchony M. Aquilina,
Clinton H. Strong,Andreu A Gage, Sidney M. Schaer,Fmnk T Frost,
Carrol].Shater, RobertG. Wilkinson,JamesR. Su/Iii-an,FrankH. Long,
Samuel Cassara,Howard R. Bamecc,Ra)mond A Hudson, Helmw A.
Mueller,PaulWeygandt,JamesF.Mohn, /ruin A Ginsberg,Mrs. Mohn,
and Casimir F. Piecraszek.

From lefc,seaced:John A. KutT)bala,l\'orberc]. Kuberka, EugeneC.
Hyz), Sylda G. Lislot·s,Allen L. Less1,1,mg,
:S•.1icholas
C. Carosella,and
CharlesH. Manno. Secondro1t·:Walter A. Olszett·ski,Jacob Lemann,
PaulL. Weinmann,Edtmrd F.Wenz/a//,HarryT Olil'er, RobertD. fuley,
and Donald]. Murray.Third row:£mesc H. Meese, William R. Kinkel,
Eugene L. Belcrami,James £. Youker, Richard F. Mayer, \'(/il/iam].
Hou-ard,Lows C. Cloucier,and RobercH. Miller. Fo1mhroil': ByronA.
Genner,£du·ard A. Rayhill, John L. ConbO),Donald M. \X'ilson,and
HerbercH. Benson.

1949 . . . . . . . . . . . . . . . . . . . . ...

1959 ...

From lefc,seaced:FredShalu-it,, Julia M. Cullen, and Joseph£. Griffin.
Standing:Edtmrd W. Rosner,J.B.Ausc,John Sharp,PaulT Buerger,Max
A. Schneider,Carmelo S. Armenia, Laurence M. Carden, and James
A. Werick.

From lefc, seaced:RobercJ. Brennen, Daniel C. Kozera, George R.
Baeumler,Sandra\'(lilcse,DorocltyC. Rasinski,Mary Ann Bishara,Joseph
F. Monce, £/con M. Rock, and Dadd E. Den,el. Scanding:JosephA.
Ferfoi,Julius\I. Rasinski,John]. McMahon,ScerlingM. Doubrata,Logan
A. Griffin, Alf M. Tannenberg,Morron H. Heafic,, Jason H. Scetens,
James R. Do::-le,Thomas D. Doeblin, and Selbert A. Chemila.

BLFFAI.O rHYSICIA:S- A:-.:D BIO~IEDICAL SCIE:--:TIST

. . .. . . . . . . . . . . . . . . . .

�Alumni Reunion

28

1964 .........

1974 ......................

.

.

From lefc, seated: Bela F. Ballo, Gerald B. Goldstein, Lillian V. Ney,
ElizabechG. Serrage,William Fleming,Da11idZiegler,and JosephA.
DiPoala.Secondrow: Paul Sussman, Stephen P. Katz, Jeffrey S. Carr,
Michael Feinstein,Michael A. Judd, RichardWolin,John F. Reilly,Anthony Ferrari,and Charles Ladoulis. Third row: lroing Scerman, ).
FrederickPainton,ScephenScheiber,Da11idA. Leff, Marl.'inZ. Kurian,
and James C. Tibbem.

Fromlefc,firscrow:ElaineMarie Bukowski, Suzanne A11ery,Gordon L.
Avery,JudyOufiero,and LawrenceA. Oufiero.Secondrow: Alan G. Bur•
scein, Sharon Burscein,and Stephen A. Yerkovich.Third row: Sandy
Piecraszek,James C. Piecraszek,Roseanne Berger-Morelli,Daniel J.
Morelli,James L. Budny, Pam Budny, Conrad F. Wolfrum, BradleyT.
Truax,ElizabethTruax,RichardJ. Buckley,Judy Buckley,Bruce F.Middendorf, Mimi Middendorf, Paul H. Wierzbieniec,Ellen Wierzbieniec,
James A. Smith, and Beverly Smith.

1969 ......................

1984 ......................

.

Fromleft, seated:Madeline). White, Moira ). Burke, Evelyn Roisman,
Marion Wind, DorocheaA. Downey,and PennyA. Gardner.Secondrow:
Hanley M. Horwicz,Gerald D. Scinziano,Louis He111ZY,
IsraelKogan,
Roberc). Gibson, James L. Ca11alieri,Michael N. Pisick, Han:ey I.
Weinberg,TimochyV Siepel,and BernardC. Muscaro.Third row: Thomas
S. Scanlon, James J. Whice, William K. Major, David S. Schreiber,
Timothy F. Harringcon,Douglas L. Robercs,and Carl ). DePaula.

AUTUMN 1989

.

Fromleft, seated:HeleneSurowiec,CherylMiller,ElaineSchaafGergelis,
Maria Billinson,Maritza Alvarado, Amy SchuecklerRosceing,Jennifer
Curletta, Lynn Picano,RoseDeAnwnis, and )ill Pfa/zer.Scanding:Roberc
W Lasek, Man: ). Koblick, Herbert B. Newwn, RichardE. Gergelis,
Mark Billinson,Andrew M. Knoll, Ke11inP.Rosteing,JosephD. Curletta, John ). Picano,John F. Noe, and Dal •id F. Pfalzer.

BUFFALO PHYSICIAN AND BIOMEDICAL SCIENTIST

�Alumni Reunion

29

JUSTWHATIs THEUB FOUNDATION?

H

1979..........

.. ..........

.

From left, seared:Tunde Kashimawo,BarbaraE. Klein, Letitia R. Clark,

IvonneS. Cellino, Andrea C. Bracikowski,Norma Creighton,Kathleen
Buran,Jody Spooner,Ellen Balon,Donna Irene,LindaA. Cardone,Gale
A. Barg,Christine A. Marino, Connie Shields, Marilyn Armenia, and
Kay Baron.Secondrow: Robin H. Adair, Ann Canty, Michael Schneider,
Susan Lehrer,BarbaraEames,FrederickA. Eames,Katlty Hall, Theodore
R. Hall, Walter A. Balon, Peter Condro, Bruce J. Naughton, Thomas
L. Mahoney, Thomas McKeever, Mary PacSchreck,Robert L. Baron,
Cindy Kaiser, and MargaretNaughton. Third row: Jason Dunn, John
M. Canty, Myra N. Rubyci, Michael Cellino, RichardT Irene,James
P. Bracikowski,JosephE. Buran, Ted H. Spooner,Donald ]. Armenia,
JamesJ. Creighcon, Peter E. Shields,John Naughcon,Jim Cardone,Roger
E. Kaiser,and John W. Crofts.Fourthrow: GeorgeBoyar,MichaelCamp,
bell, TajudeenA. Kashimawo, Andrew T Costarino,James R. Miller,
LIO)·dM. Lehrer,and Frank T Schreck.

ave you ever wondered why your gift to the School of Medicine
and Biomedical Sciences is acknowledged by the University
at Buffalo Foundation? Simply because the University at
Buffalo Foundation is the chief administrator of all gifts to the Univer•
sity. As a non-profit organization, the UB Foundation seeks, manages,
and invests private gift support on behalf of the University.
The Foundation was established in 1962 when the private UB join•
ed the Scace system to ensure that gifts for the University would re•
main at UB and not be dispersed throughout the State.
Since its founding, the Foundation has generated more than $140
million in private support. 1988 revenues totaled almost $23 million,
of which more than $7 million was earmarked for the School of
Medicine and Biomedica l Sciences.
Donors can designate thei r gifts to the medical school, a depart·
ment, a specific research project, a schola rship or even a new com·
purer. No matter what the final designation, the gift is made through
the University at Buffalo Foundation.
Just as donors make many d ifferent kinds of gifts, the University
shows its appreciation in many ways.
Individuals who contribute $1,000 or more annually to the medical
~chool receive membership in the James Platt White Society. In add i•
tion, for persons who make a commitment of $10,000 or more payable
at the rate of $1,000 annually, recognition is given through the Presi•
dent's Associates program of the University.
For more information about the James Platt White Society or gifts
to the School of Medicine and Biomedical Sciences, contact rhe Qf.
fice of the Dean (831-2775) or Mary Greene at the UB Foundation
(636-3315).
•

A NUMBER
OFPEOPLE
MADEMEMORIAL
GIFTS:

MEDICAL
ALUMNI
ASSOCIATION
ELECTS
KUNZPRESIDENT

Clas s of ' 39 Gift Fund:
• Dr. WillardH. Bernhoft- in memo1)of his brother,Frederick,a member
of the Class of '39, who passed away in his lasr year of medical school.
• Anna L. Bleich- in memory of her husband, La Moyne.
• James Marinello - in memory of his brother, Carlo.
• Connie Plummer Miller - in memory of her sisrer, Lois.
• Dr. Ann Rudmgerand David Rudinger- in memory of che1rmother,
Ellen.
• Berry Storms - in memory of her husband, Rober!.
• Harriet E. Wesp - in memo') of her husband, Et·erert.
Class of '44 Gift Fund:
• Dororh) Kennedy- in memory of her husband, Sidney.
Class of '49 Gift Fund:
• Victoria Van Coevering- in memory of her husband, Russell.
Class of '64 Gift Fund:
• Dr.and Mrs. David C. Ziegler- in mem07) of Dr. Ziegler'sclassmare
and friend, Dr. Sheldon Roth/leisch.

oseph L. Kunz (M'56) has bee n named to a one-year term as presi•
dent of the UB Medical Alumni Association.
A lso elected were Bertram A. Porrin (M '53), vice president,
and Nedra J. Harrison (M'77), treasurer.
A clinical assistant professor of medicine at UB, Kunz is a specialist
in internal medicine with subspecialties in gastroentero logy and
endoscopy.
Kunz is an attending physician at Buffalo General Hospital and
a staff physician at the Oute r East Side Clinic sponsored by the Erie
County Health Department.
He formerly was a consulting
gastroemerologist at St. Francis Hospital.
Portin, a colon and rectal surgeon, is a clinical professor of surgery
and chairman of the division of colon and recta l surgery in UB's
Department of Surgery .
Harrison, a general surgeon, is a clinical instruc tor of surgery at
the University at Buffalo.
•

BUFFAI.O PHYSICIAN AND BIOMEDICAL SCIENTIST

J

AUTUMN

1989

�Alttmni

30

175 ATTEND1STREUNIONRECEPTION

he first annual reception to honor
the members of the reunion classes
at the Spring Clinical Day/ Re'union Weekendwas held May 5 in the
Center for Tomorrowon UB's North
Campus.
More than 175 alums attended
the reception sponsored by the UB
Medical Alumni Association. The
gala event providedan opportunity for
all of the returning classes to mingle
and it set a warm and friendly atmospherefor the rest of the weekend's
activities.
We hope that next year's returning classeswill plan to attend our
second annual reception on
Friday evening, April 27, 1990.

(1-r) Mrs. Raymond Bond, Raymond Bond '44, Helmut
Mueller '44, Mrs. Paul Weygandt, Paul Weygandt '44.

The 50,year reunion class.

(1,r) Sandra Wiltse
Logan Gr iffin '59.

Leininger

'59,

Daniel

Kozera

'59,

The 25,year reunion class.

BL"FFALO PHYSICIA:S: A:-;D BI0~1EDICAL SCIE1'TIST

��Buffalo Physician &amp; Biomedical Scientist
State University of New York at Buffalo
3435 Main Street
Buffalo, New York 14214

N,n
l &lt;;
PAIi)

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MR. CHUNG-KAIHUANG
HEALTHSCIENCE LIBRARY
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                    <text>E.rly Wmrer1989

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PETScanner
. Buffalo is getting state-of-the-art imaging equipment that shows not how the body
looks, but how it works. A joint project of the UB
medical school and the VA Medical Center, the
$12 million center for Positron Emission
Tomography should be fully operational by the end
of 1991.
Meet the chairmen.UB has created a new Department of Emergency Medicine and has placed one
of the field's pioneers at its helm. Meet him and
five other new chairmen who have visions of new
ways to bring UB to the forefront in research and
teaching.

m Thoughtson a nasty day. William R. Taylor, Class
of '45, reflects on three classmates who understood
the importance of humor in their profession and
their lives.

IEJPhoto directory. Here's

an introduction
students in the basic sciences.

to the

Departments

I]

fl
Antique treasures,Page30

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Ill
Alumni au:ard, Page26

Cowerlllurnotion:JosephTh,d

People. Keep your teaching fresh, even offbeat.
That's the advice of award-winning professors Murray Ettinger and Charles Severin.
Research.A product called INFASURF significantly reduces respiratory problems in premature infants, according to a national study coordinated
by UB researcher Edmund A. Egan lll.
Alumni.George W. Thorn, Class of '29, a pioneer
in endocrinology, organ transplantation, and
kidney dialysis in the United States, received the
first Distinguished Alumnus Award from UB.
MedicalSchoolNews.Two antique chandeliers have
been restored to their original luster thanks to a
donation from Robert L. Brown, Class of '44. The
pair now graces UB's Health Sciences Library.
Classnotes.

�2

PlEI
s &lt;e&lt;r1lIl1lIl1l&lt;eJr
With plans to build $12 millioncenter,
Buffalo is poised at a new frontier

uffalo is approaching a
new frontier in diagnostic
medicine with plans to
build one of the most ad;
vanced Positron Emission
Tomography (PET) imaging centers
in the world.
PET imaging, the latest in com;
puter scanning techniques, has the
unique ability to visualize and
quantify complex physiological pro;
cesses occurring in the human
body. It has potential for important
advances in the understanding and
treatment of major ailments, in;
eluding heart disease, stroke,
cancer, epilepsy, and Alzheimer's
disease.
EARLYWINTER 1989

BUFFALOPHYSICIANAND BIOMEDICALSCIENTIST

�3

Joseph A. Preiio, M.D., Jayakumari M. Gona, M.D., and Robert E. Ackerhalt, Ph.D.

A joint project of the UB School of
Medicine and Biomedical Sciences and the
Buffalo VA Medical Center, the $12 million
center will serve the entire community, including non-veterans.
Funding of $3.4 million for the project has
been awarded by the federal Department of
Veterans Affairs. UB has committed $1.6
million.
The balance will be provided by state
grants and private support.
The James H. Cummings Foundation
already has committed $1 million - the
largest grant in the charitable, nonprofit

BUFFALOPHYSICIANAND BIOMEDICALSCIENTIST

PET centers m the
nation bave tbe
capabilities

proposed

for tbe Buffalo site.

corporation's 26-year history - to the
project.
The center will be the first PET imaging
center in the SUNY system and the only
one of four in New York State that's located
upstate.
There are some two dozen PET imaging
centers in the U.S.,but only a handful have
clinical and research capabilities on the scale
being proposed for Buffalo, noted John
Naughton, M.D., dean of the medical
school and vice president for clinical affairs
at UB.
Naughton said the PET imaging center

EARLYWINTER 1989

�4

"will be significant not only co this region,
but co the entire northeastern United
States. This project will put the UB medical
school at the very edge of a new frontier of
diagnostic medicine."
"We will be offering an imaging
technology not available in most big
teaching centers in the United States; added Joseph A. Prezio, M.O., chair of the UB
Department of Nuclear Medicine who will
serve as the cenrer's director. "It will also add
significantly to the services we offer our patients:•
The center will have two major components: a PET scanner facility located at
the Buffalo VA Medical Center and a
cyclotron facility housed in Parker Hall on
the adjacent UB South Campus.
The cyclotron facility will produce radionuclides, low-level radioactive materials,
to be used by the PET scanner.
Underground pneumatic rubes connecting
the hospital and Parker Hall will transport
the radionuclides.
The cyclotron is a specially designed electromagnetic device that will permit researchers to accelerate charged particles or
ionized atoms to very high velocities. The
particles collide with targets composed of
various elements, compounds, or gases, producing the low-level radioactive materials.
Most radionuclides produced by the
cyclotron will totally decay to a stable element within a few hours to a few days,
Prezio noted.
The hospital-based PET scanner is expected to be operational by September 1990
and the UB-based cyclotron by the end of
1991, Prezio said.
It's anticipated that other local hospitals
and private medical practices will decide to
buy scanners and use radiopharmaceuticals
produced by the UB cyclotron.
Millard Fillmore Hospital has indicated
that it will open a diagnostic imaging center
with a PET scanner, and Buffalo General
and other area hospitals have also expressed interest in getting PET scanners.
The chief of the PET scanner facility at
Veterans will be Jayakumari M. Gona,
M.O., chief of nuclear medicine at Veterans
and UB clinical assistant professor of
nuclear medicine. The director of the

EARLY WINTER 198Q

cyclotron facility will be Robert E.
Ackerhalr, Ph.D., vice chairman of the UB
Department of Nuclear Medicine and
research associate professor of nuclear
medicine.
The project has received enthusiastic support from the Western New York Health
Sciences Consortium. (That consortium is
composed of area hospitals, the UB medical
school, and the Greater Buffalo Development Foundation.)

In a 15-month

child
uncontroHeJ

( top

anJ

normal.

old

with

seizures,

center)

appear

Howevc-r, on

the PET image

(bottom),

the- dark

area

epileptic event
1s

page

occurring.

is

a view of

the PET e&lt;Juipment,

A PET scan will cost about $1,500, which
is comparable to the cost associated with a
study using CT scanning or magnetic
resonance imaging. lt is less than many invasive studies used to evaluate cardiac,
neurologic, and oncological problems, bur
without the increased risk of morbidity or
mortality associated with them. It's anticipated that soon third-party carriers will
provide reimbursement for a PET scan.
PET scanning is the newest computer imaging technique to arrive in Western New
York. The first CT scanner in all of New
York State arrived at the Dent Neurologic
Institute at Millard Fillmore Hospital in
1973. It was the fifth in North America.
The Dent also got Western New York's
first working magnetic resonance imaging
scanner in December 1982. For the first two
years, it was used only for research.
UB President Steven B. Sample noted
that Buffalo's PET center "is part of the effort of the University and its affiliated
teaching hospitals co establish 'centers of excellence' in healrh care and enhance the
regional and national reputation of the
high-quality health care delivery system in
Western New York. Its establishment also
is in keeping with our goal of moving the
University into the ranks of the top 10
public research universities in the country."
Richard S. Droske, director of the VA
Medical Center, said the cooperative effort
that led to designation of the new center
is another example of how the VA Medical
Center and the University work together
co benefit the community.
"The PET Imaging Center; he predicted,
"will lead co quantum leaps in our clinicalcare and research abilities in such fields as
cardiology, neurology, and oncology."
•

BUFFALO PHYSICIAN AND BIOMEDICAL SCLENTIST

�To get a better idea of what Positron
Emission Tomograpy (PET) imaging is,
it's helpful co compare it to the more
familiar X-ray computed tomography
(CT) scanning.
Boch are noninvasive and provide
glimpses into the human body.
There is a significant difference,
however, noted Joseph A. Prezio, M.D.,
chair of the UB Department of Nuclear
Medicine who will serve as the director
of Buffalo's new PET imaging center.
While CT scanning shows anatomic
structures in the body, PET scanning
visualizes and quantifies information
about physiological and chemical pro­
cesses occurring in body organs.
Put another way, CT scanning reveals
how organs look, while PET scanning
tells how well they function.
Because it detects disease-triggered

chemical changes in the body that are
precursors to anatomic changes and
physical symptoms, PET scanning
already has shown its value in early
detection and treatment of disease.
In coronary artery disease, for exam­
ple, PET scanning can help physicians
tell the difference between viable and
dead heart muscle.
PET scanning has potential for major
advances in the understanding and
treatments of ailments such as stroke,
cancer, epilepsy, and Alzheimer's disease,
noted Prezio. It also will allow physicians
co evaluate
the effectiveness
of
chemotherapy programs in cancer treat­
ment within one day, rather than several
months. Pharmaceutical companies will
use PET to accurately determine effective
drug dosages.
Prezio noted that PET scanning has
also been used co successfully pinpoint
the sire of electrical outbursts in rhe
brains of epileptics chat set off seizures,

BUFFALOPHYSICIAN AND BIOMEDICAL SCIENTIST

and to advance medical understanding
of brain tumors.
Another difference between PET and
CT scanning is the manner in which the
images are produced.
In CT scanning, low-level X-rays are
produced by the scanner unit and pass
through the part of the body being
studied. A computer generates a three­
dimensional image based on readings
that result from the X-rays.
With PET scanning, trace amounts of
radioactive biological compounds called
radiopharmaceuticals are introduced into
the patient's body. These radiophar­
maceuticals emit positrons, a positively
charged electron. A computer generates
three-dimensional images based on the
pattern of X-rays emitted by the
positrons.
Radionuclides, the low-level radioac­
cive materials
contained
in the
radiopharmacuecicals, will be produced
in the cyclotron facility at UB.
•

EARLYWINTER 1989

�6

N

ew names,new faces,new
directions.
Six new chairmen are
among the 19 to lead departments in UB's Schoolof Medicineand BiomedicalSciences.
Just created is a Department of EmergencyMedicine,
which will be headed by G.
Richard Braen, M.D.
The other new chairmen
areStephanieH. Pincus,M.D.,
dermatology;L. Nelson Hopkins, M .D., neurosurgery;
Robert Gillespie, M.D., Ch.B.,
orthopaedics;F.BruderStapleton, M.D., pediatrics,and Ron­
ald P. Rubin, Ph.D.,
pharmacology and therapeutics.
They have outlinedplans to
bring to their departmentsnationaland internationalreputations for excellence.
Severalchairmenhave also
been reappointed:
• JosephA. Prezio,M.D., De-

partment of Nuclear Medicine
• Myroslaw Hreshchyshyn,
M.D., Department of Gynecology and Obstetrics
• George Alker Jr., M.D .,
Department of Radiology
• James P. Nolan, M.D.,
Department of Medicine
• Leon E. Farhi, M.D.,
Department of Physiology
• Saxon L. Graham, Ph.D.,
Department of Social and
Preventive Medicine
• Harold Brody, M.D., Ph.D.,
Anatomy
• William H. Coles, M.D.,
Ophthalmology
• Glen E. Gresham, M.D.,
Rehabilitation Medicine
• David Holden,M.D., Family
Medicine
• John I. Lauria, M.D., Anesthesiology
• John R. Wright, M.D.,
Pathology
• John M. Lore Jr., M.D.,
Otolaryngology
PHOTOS
:

EARLYWINTER 1989

BOBWALION

BUFFALO PHYSICIAN AND BIOMEDICAL SCIENTIST

�EMERGENCY
MEDICINE
G. Richard Braen, M.D., has been named chairman
of the new Department of Emergency Medicine at
UB.
He is also head of the Department of Emergency Medicine at Buffalo General Hospital.
"Dr. Braen is one of the new breed of emergency medicine specialists," said John Naughton, dean
of the medical school and vice president for clinical
affairs at UB.
"He's been in the discipline since its inception.
He's regarded as an academic leader for the
discipline and is helping to set the foundation of
what the discipline is."
Braen is residency-trained and board-certified in
emergency medicine. He ran the residency program
at the University of Kentucky for several years.
He came to UB from his post as assistant professor at Harvard Medical School.
The autho r of spiral-bound manuals for medical
students and residents, his popular Clinician's Pocket
Referenceis in its sixth edition.
Braen is working on the third edition of
EmergencyMedicine: Conceptsand Clinical Practice.

Bl.ifFALD PHYSICIAN A:S:D BIOMEDICAL SCIENTIST

G. RichardBraen,
M.D., a pioneer
in the field
of emergency
medicine,is
chairmanof
the medical
school'snewest
department.

Along with a UB medical student, he's working on
another spiral-bound emergency medicine manual. 7
He also wrote Managementof the Physicallyand Emotionally Abused: Early Assessment, Interventionand
Counseling.
Getting a brand-new department off the ground
takes quite a bit of work.
"Our major goal is education, initially," said
Braen. "We'll get into research as time goes by."
The department will be very communityoriented, Braen said. It will work with pre-hospital
personnel such as ambulance staff and emergency
medical technicians.
Within the school, the new department will
work with medical students at various levels. le will
expand the offerings for emergency medicine rotations and offer services to existing cou rses that want
to include emergency medicine topics.
The three-year residency program will train IO
emergency medicine residents a year. Emergency
medicine is one of the most competitive residencies, he added.
UB's program will be based at two main
hospitals, Buffalo General and Erie County
Medical Center, with Millard Fillmore and
Children's hospitals supplementing the program.
Most emergency medicine residency programs use
more than one hospital, Braen noted.
He hopes to have the residency program in place
by July 1991.
"The big job in starting a residency program is
getting the board-certified emergency medical physicians," Braen said. "In the greater Buffalo area, I can
count all of them on two hands, maybe one hand."
Nation-wide, there are on ly about 7,0CXJ
certified
emergency medicine physicians available to fill
30,000 available positions, he noted. Since most of
the training programs are in the midwest and west
they can't keep up with the need in the east. '
Because UB's training program is located in the
east and is at a university, "we1Ibe very competitive
and in very high demand, and we'll get very good,
qualified residents in the program; Braen predicted.
The residents in tum can teach the students.
"The key is the people," he said .
Ten years down the road, Braen hopes the
department will have a fully credentialed residency program that will be supplying residency
graduates to area hospitals, that there's an appropriate interest in emergency medicine from
medical students, and that there's a well-established
research component in areas such as shock and
trauma.
•
(Fordetails on the new department, see page 8.)

EARLY WINTER 1989

�8

DERMATOLOGY
Stephanie H. Pincus, M.D., has been named professor and chair of the Department of Dermatology
ac UB.
Pincus also serves as head of the Department
of Dermatology at Buffalo General Hospital.
Board-certified in both internal medicine and
dermatology, she specializes in care of skin problems
chat are unique to women.
Her research is in a type of cell called an
eosinophil, which participates in allergic and
parasitic disease. It's found in large numbers in skin
disease.
Pincus, who is highly regarded nationally as a

teacher, comes to UB from a post as associate professor of dermatology and medicine and vice chair
of the Dermatology Department at Tufts University School of Medicine, Boston . She was also
associate dermatologist-in-chief and director of the
phototherapy unit at New England Medical Center,
Boston.
Re-establishing the national image of the dermatology department is one of Pincus's major goals.
Dermatology has a tradition of being strong in
Buffalo, she said. In view of the many changes chat
have raken place in dermatology in America in the
lase few years, it was time for re-evaluation of the
residency program.
One change was to integrate che department

SKILLED
PHYSICIANS
NEEDED
AT 'FRONTLINES'OFMEDICINE

''You

never know what's coming in," said G. Richard
Braen, M.D.
That's the challenge of emergency medicine - it's the
front lines in the fight against the trauma of major injury.
And because the emergency room is the first stop for many
kinds of cases, emergency medicine physicians need skills that
cut across many disciplines - surgery, obstetrics, pediatrics,
psychiatry, and community relations.
Braen, a pioneer tn this relatively new specialty area, has
been named chair of UB's newly created Department of
Emergency Medicine.
"l've been practicing since 1976, and I don't know of a
day tha t's gone by when I didn't see something I'd never seen
before; said Braen. "l like the variety."
Braen remembers the time he was working an evening
shift in Lexington, Kentucky. A call came in over the radio
to expect five people burned in a car accident. le turned out
that all five were deaf and mute. Because their hands were
burned, communication was a challenge - they couldn't
speak, couldn't write, couldn't use sign language.
"We had to do the best we could; Braen said.
Ac one time, the emergency room was a kind of Siberia
where the hospital's least qualified physicians were sent, or
the ER was staffed by interns.
"Then it was realized that this was where the most
qualified people were needed," Braen noted.
Emergency medicine is an important new field, said John
Naughton, dean of the medical school and vice president
for clinical affairs at UB, because as the technology of caring for patients becomes more sophisticated, people who
used to die from major injuries can now be saved.
An important part of emergency medicine is the integration with the rest of the pre-hospital system, such as ambulance staff and emergency medical technicians, Braen
explained.
"We want to make sure the initial care is high so when

EARLY WINTER 1989

they come to us they are salvageable;' he said.
Many emergency room cases are not true emergencies,
Braen noted. Emergency medicine physicians also cake care
of minor medical problems at odd hours when the patient's
regular doctor might not be in his office.
Making sure char patients are properlyreferred so they get
needed care, but avoid elaborate services that aren't necessary,
is part of the job of the emergency medicine physician,
Naughton noted.
"There's a lot of emphasis nationally on improving
emergency room care - where a lot of mistakes used to be
made," he added.
It was just a little over 10 years ago that emergency
medicine was recognized as a specialty by the American Board
of Medical Specialties. UB is one of the few medical schools
with a department in this field.
"I could probably hold a meeting of all of the chairmen
of the academic departments of emergency medicine right
in my office; Braen noted, glancing around the room. "There
are only about seven or eight, so this is a relatively uncommon position to hold."
UB decided to create a freestandtng department rather
than a division within surgery because emergency medicine
is a more defined specialty than it once was, explained
Naughton. It also cuts across many disciplines.
A freestanding academic department will be a big attraction to residents, Braen predicted.
And, since this is an area where many mistakes can be
made, having a freestanding department puts fewer people
in the chain of command and makes residents more directly
accountable, Naughton noted.
The freestanding department was recommended by a
special committee appointed by the dean. The hospital directors unanimously supported the plan, and it was in turn approved by the Faculty Council of the medical school, the provost, and the president.
•

BUFFALO PHYSICIAN AND BIOMEDICAL SCIENTIST

�more closely with other hospital departments. Dermatology's administrative and clinical offices were
mo\'ed right tnto Buffalo General Hospital.
The department also will emphasize more basic
resean.:h to educate residents in the pachophys1ology
of dermatological diseasl' and its relation to other
basic science.
"The res1dencs have, in large part, responded
very positively, and there's very good esprit de
corps; she noted.
The next goal is thl· recruitment of more dermatology faculty memhcrs for the Erie County
Medical Center and Buffalo General Hospital.
~1orc physician, are needed becau,e new regulations mandate that every patient who is seen by
a resident must also be seen by an attending
physician.
Research is also an important part of the
department.
"Ulcimatelv, we want to develop a very strong
re"Can..h program to further the development of the
specialty," Pincus said.
She also envisions that dermawlogy will plav
an important role in an increasingly busy outpatient practice in the hmpitals.
Another aim of the department is to strengthen
the faculcv clinical pranicc plan, which provides
private care on a fee-for-service basis. "I want to provide good care and use the fiscal rewards for departStephanieff.
mental development," she said.
Pincus,
\Vhen asked about her accomplishment,, Pincus points to photos of her children, ages 17, 13, M.D.,has
and I.
integratedthe
"I'd like to convev to women medical ,cudents
Dermatology
that it's not easy, but possible, to have a personal
and professional life," Pincus said.
Department
In her quest for an administrative position, Pinmoreclosely
cus was happy to find a city where both she and
her husband, Allan Oseroff, M.O., Ph.D., who is
withother
also an academic dermatologl',t, could work.
Oseroff is chief of dermatology research at Roswell hospital
Park Cancer lnsntute. Roswell'ss1mulrnneous affiliadepartments.
tion with, yet independence from, UB allows the
couple to work wgecher,with(?ut one spouse working for the ocher.
A graduate of Reed College in Portland, Ore.,
Pincus received her medical degree cum laudc from
Harvard Medi cal School in 1968.
Pincus served her internship at Boston City
Hospital and her residency in medicine at the
Umversity of \X'ashingron Affiliated Hospitals,
Seattle.
She served as senior fellow in dermatology at
the University of \X'ashington and resean..h folio\\

BlJFFALO PHYSICIA~ A,'\;0 BIOMEDICAL

SCIE?--.'TIST

9

in dermatology at Harvard Medical Sl hool. From
1987-88,she was a visiting scientist at Biogen
Research Corp. m Cambridge, Mass.
She is a fellow of the American Academy of
Dermatology and a member of the Souetv of Investigative Dermatology.
·
Pincus 1sthe author or co-author of more than
60 articles and abstracts and nine book chapters. •

NEUROSURGERY
L. ~el,on Hopkms, M.D., has heen named chair•
man of the Department of Neurosurgery at UB.
He is also Lhairman of the departments of
neurosurgery at Buffalo General Hospital, Millard
Fillmore Hospital, Children's Hm,pital, and the Eric
County Medical Center.
A local product, born and raised in Buffalo,
Hopkins comes to the chairmanship directly from
private practice.
His natural interest in arndemic neurosurgery
led him co publish a book, several hook c.hapters,
and more than 40 ahstracts and papers. He has lectured widely and sponsored national seminars in
Buffalo on the management of aneurysms.

EARLY 'IX'J!\TER l9bQ

�Because of his energetic work as a teacher and
IO clinician, several people suggested that he consider
lhe chairmanship at UB even though he was a
clinical associate professor, not a full-time
academician.
Re-establishing the reputation of the residency
program, which was on probation, was his major
goal when he started in January 1989.
"A year ago, all but one resident failed the
boards, and he was borderline; Hopkins said. "Now,
all the residents have passed, and they did well.
"In one year, we've turned around the teaching
program, and that's largely because of Jim Budny
(vice chairman of the department) ."
In order to concentrate resources and avoid
duplication of services, Hopkins aims co develop
subspecialry centers of excellence at different
University hospitals. Neurovascular surgery and
neurosurgery of the spine would be located at
Millard Fillmore Hospital; neuro-oncology, Buffalo
General Hospital and Roswell Park Cancer Institute; trauma, Erie County Medical Center, and
pediatric neurosurgery, Children's Hospital.
Millard Fillmore Hospital is building a lab for
spine research, as well as a multidiscip linary back
institute for care of patients with back problems in
conjunction with the medical school's Department
of Rehabilitation Medicine.
An exciting area that's being developed at
Millard Fillmore is endovascu lar neurosurgery,
Hopkins said, which can sometimes eliminate the
need for open surgery or make surgery much safer.
For example, a tiny catheter could be inserted
at the groin and moved through the artery up to
the head. Then doctors can inject fluid through the
catheter into a tumor or vascular abnormality to
take away its blood supply. This procedure could
cut the hospital stay from 10 days co just a day or
two in some cases.
The department also is concentrating on
neurologic diseases of the spine and has recruited
two outstanding young surgeons who are experts
in treatment of patients with spine disorders.
"Back pain is the most common cause of disability in the U.S. besides the common cold; Hopkins
noted.
The department is also trying to develop a program for care of brain tumor~ with Buffalo General
Hospital and Roswell Park Cancer Institute.
Hopkins received his bache lor's degree from
Rutgers University and graduated cum Laudefrom
Albany Medical College in 1969.
He served his internship in surgery at Case
Western Reserve, then served as a resident in

EARLYWINTER 1989

L. NelsonHopkins
,
M.D., aims
to develop
subspecialty
centers of
excellence
at various
University
hospitals.

neurology and neurosurgery at UB. He is certified
bv the American Board of Neurological Surgery.
Active with the Congress of Neurological
Surgeons, he is general chairman for this year's annual meeting and last year was scientific program
chairman.
Hopkins is the chairman of a computer subcommittee of a joint committee on education for the
two national neurosurgical organizations. He also
chaired a subcommittee on drugs and devices for
the two organizations.
He's a member of the executive committee of
the Congress of Neurologica l Su rgeons and has
served as a member of the editorial staff of
Neurosurgery,rhe group's journal.
•

ORTHOPAEDICS
Robert Gillespie, M.0., Ch.B., who had been
acting chairman of the Department of Orthopaedics at UB, has been appointed chairman .
A member of the faculty of the UB medica l
school since 1985, Gillespie is a professor of orthopaedics . He is also director of orthopaedics ac
Children's Hospital of Buffalo.

BUFFALOPHYSICIANANO BIOMEDICALSCIENTIST

�Establishing a coordinated research program and
an organized sports medicine component are two
of Gillespie's goals for the department.
"I want ro establish a vigorous research base," he
explained.
Central laborarory facilities for all aspects of orthopaedic research will be located in renovated
space in Farber Hall, the old dental school building,
probably by June 1990. He also plans to establish
a clinical research office with computer linkages
throughout affiliated hospitals. Gillespie is working to recruit an established leader in orthopaedic
research.
Recruiting is also under way for a new scate-ofthe-art sports medicine center . The center, for patient care and research, will be established in conjunction with the Family Medicine Department,
che Division of Athletics, and other departments
at UB.
le will provide overall health care for UB's varsity and intramural sports reams, students who want
to gee fie and stay fie, and other residents of Western
New York.
One of the strengths of the Department of Orthopaedics is its strong teaching program that offers excellent, well-rounded training for residents,
especially in spine and hand surgery, trauma, and
pediatrics. The residents have a very high success
rate on the orthopaedic board exams, Gillespie said.
"And we are optimistic that we can move our
training program - which is already well respected
- to a level where it is regarded as one of the major
orthopaedic programs in the country," he said.
"Part of that process is to enla rge our research
fellowship program co facilitate our research
capability and to be able to build a stronger and
more complete research experience into the residency training program itself.
"We hope to build and strengthen our contacts
with other departments th roughout the University, especially Engineering, Physiology, and Health
Related Professions."
Before coming to Buffalo, Gillespie was an assistant professor in the Department of Surgery,
University of Toronto and an orthopaedic surgeon
at Toronto's Hospital for Sick Children.
He also was a consulting orthopaedic surgeon
and clinic chief of the amputee service at Ontario
Crippled Children's Center in Toronto and on the
staff of the Department of Orthopaedic Surgery,
Orthopaedic and Arthritic Hospital, Toronto.
Gillespie is an orthopaedic consultant to the
Pediatric Institute of Krakow, Poland, which operates under the auspices of Project HOPE .

BUFFAl.O PHYSICIAN AND BIOMEDICAL SCIENTIST

RobertGillespie,
M.D., Ch.B.,plans
to establish

Since 1970, he has been active in the research
into the problem of children with spinal deformities 11
and congenital limb deformities. The author of
multip le publications and book chapters on these
topics, he has also been an invited guest speaker
in many major centers around the world .
He received bachelor of medicine and surgery
degrees from Sc. Andrew's University, Sc. Andrew's,
Scotland, in 1959.
He was named a fellow of the Royal College of
Surgeons of Edinburgh in 1965and a fellow of the
Royal College of Surgeons of Canada in 1969.
Gillespie has served for the past four years on
che board of directors of the Scoliosis Research
Society of North America.
•

a coordinated
research
programand
an organized
sports medicine
componentin
orthopaedics.

PEDIATRICS
F. Bruder Stapleton, M.D., has been appointed
chair of the Department of Pediatrics and the A.
Conger Goodyear Professor of Pediatrics at UB.
He also serves as pediatrician-in-chief and chair
of the Department of Pediatrics at Children's
Hospital of Buffalo.
A nationally recognized pediatric nephrologist,

EARLY WINTER 1989

�12

i
Stapleton previously was professor of pediatrics and
chief of pediatric ncphrology at the University of
Tennessee Center for the Health Sciences in
Memphis.
The first step toward developing a nationally
recognized academic department is to strengthen
its already fine faculty by recruiting talented scientists who can also provide the state-of-the-art
clinical skills in pediatrics, Stapleton said.
The lack of a research building to show candidates is an impediment to recruiting, he noted.
UB's planned research building will help, and there
arc plans for Children's Hospital co gee additional
research space in the next five years.
Another recruitment hurdle is the limited
number of people going into academic pediatrics.
But UB's Department of Pediatrics has several
points in its favor, Stapleton pointed out. It's affiliated with Children's Hospital of Buffalo, a strong
pediatric hospital with a unique feature: it's the only
children's hospital in the continental United States
with a high-risk delivery service and a strong
neonatology program.
Children's Hospital enjoys a great deal of community support and there's a very close relationship between the hospital and the University. The

EARLY WINTER 1989

F. BruderStapleton,
M.D., is recruiting
talented scientists
to strengthen
the fine faculty
in the Department
of Pediatrics.

hospital is clearly oriented to support the move to
national recognition for academics, Stapleton
added.
Because UB has a system of affiliated hospitals
rather than a single medical center, faculty in
pediatrics can draw upon the other hospitals, such
as che Roswell Park Cancer Institute.
The drawback, though, is that Children's
Hospital is geographically separate from the core of
scientific activity at UB. Because researchers have
to travel between sites, "it takes tremendous commitment to meet patients' needs and conduct
research; he noted.
Stapleton received his medical degree in 1972
from the University of Kansas Medical Center in
Kansas City, where he also served as chief pediatric
resident and a fellow in pediatric nephrology.
Before joining the University of Tennessee, he
was on the faculty in pediatrics at the University
of California at San Diego and the University of
Kansas Medical Center in Kansas City.
He also served as co-associate director of the
Clinical Research Center at the University of Tennessee and medical director of its Pediatric Unit and
as direccor of research for the department of
pediatrics at LcBonheur Children's Medical Center
in Memphis.
Author or co-author of 88 scientific papers,
Stapleton has done extensive research in urinary
and kidney problems in children.
He participated last year in the development of
a consensus doscument prepared under the auspices
of the National Institutes of Health chat focused
on a long-rage plan to combat kidney and urological
disorders.
A fellow of the American Academy of Pediatrics,
Stapleton is certified in pediatric nephrology.
He was recently elected a member of the
American Pediatric Society in recognition of his accomplishments in pediatric research.
Stapleton also was elected co the executive council of the American Society of Pediatric Nephrology.
He is a member of the executive council of the Internacional Pediatric Nephrology Association and
the national executive board of the American
Board of Pediatric Nephrology.
•

PHARMACOLOGY
Ronald P. Rubin, Ph.D., has been appointed professor and chair of the Department of Pharmacology and Therapeutics.

BUFFALO PHYSICIAN AND BIOMEDICAL SCIENTIST

�___

-_-_

___

--~-

----

-

---~

Rubin previously was professor of pharmacology
at the Medical College of Virginia, where he had
been a member of the faculty since 1974. Before
chat he was on the faculty of Downstate Medical
Center and Hunter College.
After receiving his undergraduate degree in
biochemistry from Harvard College, Rubin attended dental school at Harvard University, then
switched gears and obtained his master's degree in
teaching from Harvard.
He taught high school science for a year before
he decided co go into pharmacology. In 1963, he
received his doctorate in pharmacology from the
Albert Einstein College of Medicine.
Rubin's goal is to build a department of national
and international repute. He emphasizes chat he
is seeking quality, not quantity.
"Quality begets qualicy; he noted. "People build
reputations individually. We're not dealing with a
numbers game. When I retire, I want to be
remembered for having built a good department;
nor a large department.
He's crying to recruit a "critical mass" of faculty
with world-class reputations. In the next four or
five years, he wants to see the faculty invited to national and international meetings.
"If you have a good department, several faculty
members should go on co be chairmen of their own
departments; Rubin added. "We've identified a
couple who could be in the next few years."
One of che strengths of the department is its
good young research faculty. Rubin has recruited
a colleague from che Medical College of Virginia,
Suzanne Laychock, Ph.D., and he's looking for two
additional people.
John Naughton, dean of the medical school and
vice president for clinical affairs at UB, has been
very supportive and understands the need to bring
in outside people, Rubin said.
Having chis critical mass of fine faculty members
will in turn attract fine pre- and pose-doctoral
trainees, Rubin added.
It's important co have an active graduate program with approximately one student per faculty
member. You need that blend of pre-doctoral
trainees, post-doctoral trainees, and faculty for an
optimal intellectual environment, he said.
To strengthen che department's teaching program even more, Rubin plans co interact more close1y with the Department
of Biochemical
Pharmacology in UB's School of Pharmacy.
Research is an important part of the department, and Rubin expects the faculty to be productive. However, he stresses that grants are only a

BUFFALO PHYSICIAN AND BIOMEDICAL SCIENTIST

-

13

RonaldP. Rubin,
Ph.D., emphasizes
that he is seeking
quality,not
quantity,for the
Departmentof
Pharmacology
and
Therapeutics.

means to an end. He'd be satisfied with a productive faculty member who had one grant. And if a
faculty member had two grants and wanted a third
Rubin would want to make sure the faculty membc;
could handle it.
"My goals are productivity. My goals arc quality, not quantity," Rubin stressed. "I think this
department as a group feels that.
"I'm not against grants; I'm against making grantgetting the goal of your work."
Rubin studies secretory mechanisms, also
called signal transduction. He focuses on calcium
as a mediator of secretion.
The author or co-author of more than 80 scientific articles, 19 book chapters, 2 monographs, and
numerous abstracts, he also serves as field editor
for cellular pharmacology with the Journalof Phar­

macologyand Experimental Therapeutics.
He won the faculty member of the year award
for excellence in research from the Medical College
of Virginia.
A member of the American Pharmacology
Society and the Endocrine Society, Rubin was on
the Public Information Committee of the Federation of the American Society of Experimental
Biology.
•

EARLY WINTER 1989

�14

Bv WILLIAM R. TAYlDR, ~1.D.
n the second day of January, the
weather in California was so cold
and nasty chat it reminded me of
Buffalo. I began watching two large gray
squirrels playing tn a naked oak tree.
They were running at top speed, alternating
the lead, up and down branches, then jumping many feet co another tree. All this was
50 feet above the ground, on wet footing
and in the rain. Their obvious joy and pure
fun broke me out of my slowly developing
depression, and changed my thinking to
happy thoughts from 45 years earlier.
A great day in the history of medicine was
Jan. 2, 1944. On that d:w penicillin was
released for u,e on the general population
and memhers of the Class of 1945 were
assigned their first live patients. We were
designated a, "junior clinical clerks" and
called "Doctor" bv thl· knowing nur,es.
That day was also cold and wet in Buffalo. We were herded mto a large room
where we met Abe Aaron, full professor of
medicine, in charge of converting us
"masters of ac.adem1c theory" into "dinicians" - Ill ahout one hour.
The most memorable subject covered bv
Dr. Aaron chat day wa, the role of humor
in the pracm:e of mediune. He proposed
char etery disease inflicts a secondary effect
on the psyche of the patient and that chis
ranges from simple worrv to depre~sion. It
is also similar among their kinfolk, if not
worse. He assured us that the presence of
the physician could etther lift or further
depress the mood of the sick room and we

Jl/uslralions
EARLY WINTER IQ~q

must never forget chis potential. He used the
word "humor." This must never be of a flippant type, hut a "discreet and appropriate"
type; when the doctor leaves the room,
ewryone involved with the disease should
foci better.
This is espt.•dallytrue in those cases where
,pccific therapy \\ ill not cure the primary
disease. Abe Aaron then proiected ro our
future and promised us that a good sense
of humor would be necessary if we were to
survive 111 the potennally depressing career
environment of disease. Meditating on the
above leads me to update three inadequate
t)bituarv notices.
While our Class of '45 mav not he the
most outstanding in every category, we certainly had the greatest collection of True
Humori.,ts. It is a sad reality that our three
greatest humorists have re,encly died. The
ohicuary notices 111 chis UB alumni journal
missed their real greatness when they factually reported: Mamn Downe',', Jr. ane,thesiolog1st; Joseph Rutecki-surgeon
and anatomist; George Fuggm-urologist.
I would like to introduce you to these three
outstanding members of my c.lassand offer
a few thoughts concerning their true
greacnes:s.Furthermore, should they (Xlssess
that elusive nbility co read this from their
position in the Great Beyond, I would like
them to know how much I admired themthen and now.
I met Joe Rutecki fir~t because we both
went to R1vcrs1deHigh Sthool, where I was
a vear ahead of Joe. Accordingly, I did not

t'/ JoseplJiie/
BUFFALO PHYSICIAN ASD BIOMEDICAL SCIENTIST

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�16

know Joe very well, after all, he was only che laseof a long line of Ruceckis. Joe
was known co be unusually smart, bur
nor as flamboyant as his older brother.
We all knew him as a nice kid. We didn't
know che term "humble; but he was that
coo.
I next met Joe in anatomy lab on the
morning of July 5, 1942, the day our class
started med school. I was with him every
day for the next three years. I had the
only car going from Riverside to med
school and I drove Joe to and from every
day.
There was a constant attitude of
humor that grew more inescapable as
time went on. This was every day in the
car, in the classes, and in our frequent
bull sessions which were often about a
very real WW II, which was not always
going well for us.
Joe had a specific type of humor we all
noticed: he never extracted humor ac the
expense of any other person. We identified Joe's humor as "benign humor." I
think of the humor of Red Skelton as
"benign humor" and that of Don Rickles
as "malignant humor." I cannot separate
Joe's humor from his sharp and quick
mind, which may explain why he made
med school after only three years at
Canisius College. Joe very rapidly
changed from "just another Rutecki."
Since he was "Ru" and I was "Ta"in the
alphabet, we spent both years of our
clinical clerkship not only at the same
hospitals, but in the same small groups.
It was in the clinical setting chat we saw
him use the type of humor char Abe
Aaron called "discreet and appropriate."
He was often with a patient in the
desperate throes of a terminal illness, but
I could not help noticing how his innate
humor spilled over co make the patient
somehow feel better. This was not a
phony act just because Aaron had cold
us to inject a dose of humor; this was the
real Joe who had chis quality from rhe
cradle on. Another word we muse use is
"sincerity; which he had in full measure.
Among his colleagues, Joe was noted
for coining nicknames and propagating,
if not originating, "rumors." When the
med school was between deans, he
wanted to start a rumor campaign to get
our most eligible classmate appointed.
Norm Chassin was not elected, bur he

EARLYWINTER IQ8Q

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was a dandy.
When I lase saw Joe Rutecki it was at
our 1985 class reunion. Several of us were
in a conversation when Joe joined the
group. A classmate said: "Here comes Joe
... now we will all scare laughing." I don't
remember che derails of the conversation, but the laugh titre went sky high.
As his special "benign" humor went to
work on his beloved classmates, he was
personally carcinomatosis, bur concealed the grim fact. He was a great guy
for me co have known.

C

hronologically, the next one I met
was George Fuggin. This was in
September, 1938 when we both scarred
pre-med on campus. We met more literally when we both went out for frosh foot•
ball. On the first day he played defensive nose tackle and I played offensive
center. We bashed each ocher all afternoon. My mother ended my career when
she refused to sign the parental consent
to play. I don't know if George's mother
scuttled him in a like manner, but I was
sure he would not make the team. He was
300 pounds-plus of humor and fun; not
an ounce of meanness in him. Through
countless encounters, four years on cam-

pus and then three more in med school,
George Fuggitt was always the "court
jester" and a dam good student, coo.
In med school he was in all my preclinical classes, but he was "Fu" in contrast to my "Ta" so we were on opposite
sides of most rooms. George met Gene
Morehouse in med school and their
chemistry hit it off. They had a running
pseudo-feud chat injected humor into
every situation. Since George was over
six feet call and always on the upper side
of 300 pounds, he was dramatically bigger than Gene, who played the straight
man. This pair we called our "Laurel and
Hardy." Their humor was not necessarily classic benign, but it was also never
malignant.
At the 1980 reunion party, George was
the master of ceremonies. His spontaneous and continuous humor further
underlined the rumor (possibly started
by Rutecki?) chat George was the only
doctor who had his patient laughing
during a prostate massage. It is good that
George chose urology, where humor is so
appropriate.
I last saw George at the 1985 reunion.
He couldn't be the MC because the
ravages of his rumor diminished his ability - but not his beautiful smile. His
humor fit well in his huge countenance.
The last of our trio was Marty
Downey. He sat two stools co my right
in histology lab and we met for the first
rime on the afternoon of July 5, 1942. At
that time l evaluated him as a quiet, incelleccual type. ln those days he started
no conversations, but always joined in
with comments on all subjects. His comments were always very appropriate and
usually raised the level of conversation.
He was more a Catholic philosopher
than a humorist.
As the freshman year progressed, he
became more relaxed and the humor
began co show. It was especially effective
because of his original reputation as an
intellectual.
Marty Downey and George Fuggitt
contrasted in many ways: George was at
all times a gross extrovert; George was
the biggest man in the class and Marty
was probably the smallest; George was
not a football payer and Marry was. But
both were equal in the quality of their
humor.

BUFFALOPHYSICIAN AND BIOMEDICALSCIENTIST

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By October, 1942, we had spent three
full months with the freshmen dentists.
While we spent every afternoon in labs,
they were having a series of picnics with
endless beer and spectacular couch football games. The lace afternoon lab
schedule was aggravating enough, but
their arrogance abouc their games was
building our resentment to hatred.
We finally arranged a showdown game.
On the team were several former college
star players, but chose Dents were pros.
They beat us 35 to 7.
Marcy Downey was our entire offensive threat and they identified him immediately. He was so fast and shifty that
he was the only one co gain ground all
day. The Denes would frequently cackle
Marty because they were afraid a mere
touch might miss this dancer.
Each time Marty would bounce up in
testimony to his great physical conditioning, and each time he would make a
snide remark about the rough game, but
in a manner chat both sides had co
laugh. By the end of the game he was
both our M.V.P. and top humorist. We

arrival. They were not disappointed at
the plight of this terribly proper bronchoscopist. We were convulsed ar rhe
retelling.
ln my medication on the theme, l am
somewhat disappointed that Marry
Downey chose anesthesiology for his
life's work. It is regrettable chat so many
of his patients were sleeping rhrough his
humor .
Bue, to remember the second admonition of Abe Aaron, the physician needs
a good sense of humor to survive a career
in chis potentially depressing environment of ours.

all had to use humo r co accept chat terrible beating, but Marcy was the best.
The last time I saw or heard Marty
Downey was on the occasion of our 35th
reunion. In a small group setting, Marry
reviewed a case which he had not been
forewarned about. The first inkling that
it was co be a sex change operation was
when the surgeon in charge made his initial bold incision, actually excision, to
change a boy into a girl. This surprised
the anesthesiologist, who was attempting
to sec up a very proper chart. He gave a
resume of the surgery and the comments
in the O.R. by all of the various members
of the O.R. ream.
Marty convulsed chis audience, which
led him into a discussion of the
gastrocolic reflex of Herman Boser. It
seems chat at 9 a.m. his urge to respond
to the reflex would have to be answered.
Ac 8:45 a.m., Marty set up a phony occupant in each of the two toilet booths
in the doctors' lounge at Buffalo General
Hospital. He then locked the doors and
climbed out over the partition. Then the
boys all sat back and awaited the urgent

BUFFALOPHYSICIANAND BIOMEDICALSCIENTIST

&lt;T here is one more unique circumstance that involved all three:
ASTP. ln July, 1943 the military took
over all the approved medical schools
with a program called "Army Specialized Training Program."
Our three heroes were all soldiers, first
as privates and later promoted to Pfc.The
olive drab uniforms were wool, which
can get hot and itchy. Mass formation
each 0800 our in High Street was awful
as witnessed by us Navy men wacchin~
them from the comfort of inside.
Worst of all was the military protocol,
which demanded that these privates
behave as subordinates to the corporals,
sergeants, and most especially the major,
who constituted the staff. All the above
stimulated the funny bone of our class
instead of breaking their spirit. There
were many other classmates who were
humorists in this regimented lifestyle,but
none greater than our Big Three.
These were three great men who have
left a hole in the remnants of the Class
of '45. The level of humor will be lower.
If we allow these three men to die and
fill an obscure niche in a stack of
obituaries, the cause of humor in
medicine will be offended. [ hope there
is some professor of medicine at UB who
repeats the message of Abe Aaron, and
impresses the budding doctors chat
humor should be a big part of their
careers in medicine.
I am quire sure each class will have
potential
Ruteckis, Fuggitts, and
Downeys, and they should be officially
encouraged in this beautiful line of
therapeutics. Can you now see why l love
these three men?
•

J

EARLYWINTER 1989

J7

�Graduate Students

he scientist values research
by the size of its contribu,
tion to that huge, logically
articulated
structure
of

''

ideas which is already,
though not yet half built, the most glorious
accomplishment

of mankind?' - Sir Peter

Brian Medawar (who won a Nobel Prize
for his work in immunology). The grandest
of goals is shared by the graduate students
who are entering the University at Buffalo
School of Medicine
and Biomedica l
Sciences. As it did in the last issue for the
medical students, the Buffalo Physicianand
Biomedical Scientist now presents a photo
directory of the new graduate students.
Their biographies inc lude undergraduate
major and degree, unde rgraduate institu,
tion, and current department.

�Graduate )tudents

19

Susan Lynn
Dagenais,

Peter Augustinos ,
B,ologyB.A., Hofstra
Unitermy, Pacholoin-1
u:,sh co gam more
knou:ledgeabouc the
human bod,.

Kathleen E. Bethin ,
Bux:hem1s1ryB.S.,
Unlt'ers11y
at Buffalo,
Biochemistn. l am a
jomt M.D. ·. Ph.D.
student.

Reva Bhushan ,
BiologyB.S. and
Chemistry B.S.. Si.
FrancisCollege,
MicrobioloJ::,'.
1 ha,e a
ma.1ter'sdegreefrom
Rhode Island m B,ologv.
1 am 1nten-s1ed
m
research,oil pam1mg
and baiik.

Manja H.E.M.
Bouman , Biochemistry
Engineer,Hogeschoolf nterstudie,Biochemistry.
I'm from rhe
Nerherlands.l pla,
Korfbal.

Margaret Christine
Grabb, Bwlogv B.S.,
Un1&lt;ers11y
at Buffalo,
M, fa,orue
Physiolog:,·.
sporesare u&gt;lle-balland
basketball.

David A. Judd ,
B,otechnologv,RlT,
B,ochemistn. l u·ould
ratherbe d~mkmg.

Chong-Hyun Kim ,
Microb,oloi('iB.S., Seoul
Nauonal Uni,emiv,
Physiology.M, fawrite
spori is bou·lmg.

Won-Ki Kim , PharJungsook Cho Lee,
1rtac\ B.S. and M.S.,
Pharma" B.S., Seoul
Seo,;!Na11onalUn1te~,- l\'auonal Unn.ersH~.
t), Pharmacolog:,.
l like
Pharmacnlog,.I came
plavmg iennis l am a
from Korea.
neu· Ph.D. studenl in
pharmacolog,.

Laura Jane
Nicho lson, B,olog:,
B.A., l.lni,·erm, of ·
Delauare, Micmbwlogv.
l came 10 Buffalo from·
~for.land and for UB's
.\1.0. • PhD. program.

Xin Sun, B,ochemism
B.S., Fudan Uni,·e"uy:
ShanghaiProunce,
B,ochemistr..;'..h faiher
is a professorm •
biochemiscr..1 ihmk I'll
uork on biomedical

Miriam Helene
Tiktinsky , Phy1ical
Theraf1\B.S.,
Washmi:conUni,m11y,
Pms,olo![).Afier eight
w,m as a P.T.,I'm gomg
back co school10 do
research.

Meng-Hang Xia ,
Tox1cologv
B.S.,
ShanghaiMedical
Unn ern1,, Pharmacolog,:I'm from
Chma. 1 am a Ph.D.

Meiheng Yang,
B1ochemmr.B.S.,
Sichuan Uni, mu,,
B,ochemmr.. l came
here on July 26.

Zhaohui Yang,
Biochem,sm·B.Sc., Pe-

science.

1ruden1no-.,·.I u·ill enjO\

B,ochenmrnB.S.,Norih•
em M,ch1gan

Unit·mir,, Parholog:,.
I
ha,·e an M.A. m
biolog,. I ha,e an miere.&lt;tm research.

Shih-Ping Yang,
M.D., NarionalDefense
Medical Cenrer,
Physiolog:,.
l am a
graduaresrudentof rhe
departmentof
pms,ology

Yuan Gao, Medicine
B.S.C. PekingUnion
Medical College,
B,ochemmr.. I chose
UB becauseu's a
famou~umt'ersuy.

king Un1ternr,,
Bioch,mmr.. I am

onginalh from Chma.
10te l.!B.

If.

Photoswere
unavailablefor:
John Delyani ,
Physiolog:,
Haiping Mei ,
M icro&amp;iolog,.

�People

20

Offbeatand Proudof It
Ettinger will do anything to spark students' interest

"1

try to convey in an emotional way,
what's exciting about the subject.
I do a lot of 'offbeat' things to stimulate excitement and interest; Murray Ettinger, professor of biochemistry, said from his
laboratory.
"I have no pride. I'll do anything to create
interest and understanding."
Ettinger was describing some of his offbeat
methods of reaching.
"[ meet people ten years lacer and one of
rhe first things they mention is collagen
superstar~ Ettinge r said a former student gave
him this title.
"I go overboard crying to get people to
understand why collagen (a structural protein) is so exciting," he said.
But collagen isn't the only subject to get Ettingcr's unusual treatment. "There is a concept of how enzymes work called induced fit.
I used a thinly disguised analogy ro mutually happy sex."
Bur Emnger's offbeat approach isn't limited
to a single class. "I taught an advanced
graduate course and I decided nor to give any
exams. Then I found out what rhe great
motivator is: a berter motivator than
grades ... • Ettinger paused with a twinkle
in his eye.
"I said, 'Put your hand on the buzzer as
soon as you chink you have the answer.
Whoever understands it first will get a dozen
doughnuts:"
Pastries, apparently, motivate students better than finals.
These methods apparently are working.
SUNY Central recently named him a
distinguished teaching professor, one of the
highest honors in the system.
This is not the first rime that Ettinger's

EARLYWINTER 1989

By DAVID M. SNYDERMAN
teaching excellence has been recognized. He
has received two Louis A. and Ruch Siegel
Teaching Awards and many letters of commendation.

"Put your hand on the
buzzer as soon as you
think you have the
answer. Whoever
understands it first
will get a dozen
doughnuts," Ettinger
told his students.
Pastries, apparently,
motivate students
better than finals.

T

he medical school class of 1979 dedicated
its yearbook to him and he received the
S.N.M.A. Award for Service co Minority
Students in 1988.
"I really felt good about that because I have
spent a lot of rime trying co help minority
students; Ettinger commented.
Ettinger has serious accomplishments co his
credit. He has developed several classes, one
of which is an elective honors biochemistry
course for medical students.
"Several students said they were just bored
with the first year of medical school.
"It's an informal, graduate level course
where the students learn from each other.
Two co four students identify a disease that
they arc interested in. I help chem a licdc bit
finding papers about the disease," explained
Ettinger .
The class has examined such diseases as
Down's Syndrome, sickle cell anemia , systematic lupus, Parkinson's, diabetes, muscular
dystrophy, and schizophrenia.
"lc'swhatever the student wanes. Everybody
in the class reads the papers. All that the people who choose the diseases do is lead the
discussion. They learn by informal conversation about what they read. And then the
following week, we get together with a physician and a patient." This helps the students
get a better understanding of the disease,
Ettinge r noted.
"I've (also) organized a summer program for
people who have failed biochemist ry. The objective is not only to learn and pass
biochemistry but to learn an approach to
understanding any subject," he said.
Ettinger teaches methods of learning in this
biochemistry course. Students are told they
should take the lectures and then, "paraphrase

BUFFALOPHYSICIANAND BIOMEDICALSC!ENTIST

�People

21

1nternah:c 1t, ~ct II mto vour m, n word .
Iii he a good ,tudent, vou have to lome up
\\ 1th your O\\ n 'ICU point. \\'hnt a good
tcachcr dOC! 1s ,umul tc you to do chat.
•t \\ould like p,.:opll' t&lt;&gt; undcr,t.md what I'm
t.ilking .,bout ,o that tlll'y rnuld solve a rnrn•
plctch nc-., problem•

11,

or Emnger, tead11ng add, 'Pile to life.
"I like the \'ancty of mv Job. I enJO) my
I would go
re5c:mh but 1f I did Ju t r=rch,
half hall), Teaching gl\cs me rnntan \\1th

F

people."
"1th111 a
teach mg exist
Et unger'
order to
"In
hO\\L'\er.
frame-.,ork of rc,,carch,
get a J1 t 111guished te,1&lt;hmg pmtc sor,h1p,
fir&lt;t of nil \'&lt;)U han· to hen prof&lt;'S50ran&lt;l vou
can't he a profo-or "1thout being a uccessful
researcher."
Trained ,1, n protl'III &lt; hem1,t, l:tt111~crmm
\\Orb "11 h rnecalocn:ymc,, •pc-c1ficallvtopper o:1:idasc.
"I'm intl'f('!,tcd m the role of copper m
h1ology," lw ,,ud.
"Sumulatcd h, quCl&gt;t1on, from m\ O\\ n
graduate cudcm,, our work in recent ~car
has dnhl·d towards H'llular hmchem1&lt;trv ol
,oppcr; th,ll 1,, how cdl move nroun&lt;l and
use copper, and mhcmcd d1,-ca~ of copfl&lt;.'1'
b1ochcm1 try (,uch a \X'1l,-0n'sdt l-a,e).
"\\'c u,l' the d1,ea,l' ,1s :- rool," he ,ay,. "If
not only rnn we cure
figure out the d1!-&lt;:asc,
the d1~. se, but \\C find out 50me1hmg tm
portant about hm, normal cells u e copp~:r."
EmngL·r\ n&gt;mmllrnl'lll ro re&lt;l'.lr&lt;h makes
lum a be Iler m,cruc1or, he said. "The old
a~~c that tcachmg and research complt:mcm
&lt;':I&lt;h 01 her 1~ true."
Hi, 1ead1111gmetho,.h ure ha L'd on mak•
ing an 1mprcss1on, Emngcr ,aid One of his
former student, rold Emngcr that one of the
pmfc,,or's 5ta1cmcnt ,ihuuc "ho\\ ,Hw1h111g
that can r,lllonallv happen probahh \\tll be
bsencd in 50mc Lanett &lt;)&lt;tern• had become
the ha~• for that phys1c1an's pracucc ol
0 med1eine.
"It reall) madc me feelgood."
§ for Ettmscr,teaching rs a =pons1b1ht~ n t
R t,) fic takl·n lightly. "I'm t hL·onl' \\ ho 1&lt; ,urn•
lt 111,m:mgI he wholc ,rnw of knowk&lt;lgc about
the ,uhJcct. \XO\\! That' rcalh a prl\'llcgc: •

,,c

I

\furra~ Ettinger, Ph.D.

BUI!'AID PHYSICIA~ A~D lll0\1EDICAI SCJE:-:TIST

EARLYIX'ISTER198'1

�People

22

Keep It Fresh
Severin wins Chancellor's Award
for Excellence in Teaching

//E

ach student has his limitations.
You have co adjust your teaching
to the student," says Charles
Severin, associate professor of Anacomical
Sciences.
His willingness co adjust, along with his excellent teaching methods, have won him a
Chancellor's
Award for Excellence in
Teaching.
One of rhese adjusrmenr, occurred wirh the
student of a colleague. Severin, who teaches
gross anatomy (primarily to medical and dencal students), was asked for suggestions by
Judith Tamburlin, clinical instruccor in
anatomy, who teaches the undergraduate
gross anatomy class.
"A couple of years ago, she had a blind student enroll in a class," Severin began.
"Anacomy is a visual subJect; there are areas
in anacomy that are cough for a sighted student to understand.
"After finding that there weren't any
teaching aids at this level for her, we designed this for her."
"This" is a braille, raised relief, gross
anatomy textbook made especially for Lisa
Hoffman, Tamburlin's student. Accompanying the raised drawings are explanations both
in braille and on tape.
Severin and Tamburlin recently received a
two-year, $154,000 gram from the National
Science Foundation to develop and assess a
similar book for high school students.
Writing the accompanying texts was a task
that beneficed his regular teaching duties.
"Ofren the descriptions we used co teach
her, we now use co teach the sighted because
they were clear and concise," Severin said.

EARLYWINTER 1989

By DAVID M. SNYDERMAN
Bue Severin maintains his efforts co help
students day in and day out and doesn't limit
those efforts to an occasional pupil.
Because medical scudenrs have long,
unusually inflexible schedules, Severin found
it difficult to find office hours agreeable co
everyone involved. As a result, he now meets
most of his students by appointment.
'I've met with students at seven in the morning, eight at night, and on weekends, if they
need help,"he explained. "Some people would
call it great lengths, but I Just consider it pare
of my job.
"I try co make my hours as flexible as possible; I cry co help students as much as I can.•

S

everin said he has found the students
extremely dedicated, once they have come
co him for help. "I would make appointments
for seven in the morning. I would get here
sometimes at ten minutes to seven and I never
bear the students here."
Severin cakes the special insights he received as a student and passes them along to
his pupils.
"I try to present co the students little rricks
and techniques that I use co remember the
subject," he said.
One of the "tricks" is co draw the
anacomical structures from memory. In fact,
Severin asked Lisa Hoffman co cry to draw
the pictures that he and Tamburlin had
transcribed for her. Hoffman walked up to the
blackboard and drew the structure, he said.
"There was lots of overlap," Severin said,
"but she could do it."
Another trick that Severin suggests is "to
place chem in the body. You can sit there and

memorize rhe conrenrs of the anacomy text,
but it's just words."
So, he asks students co imagine chat they
are inside the body, telling them to look
around at the structures that arc there.
"Anatomy allows you to do that because it's
basically a visual subject."
This technique, he said, help, students
to remember the anacomy long past the
final exam. To Severin, it is important that
they "remember it ten years from now~
One of his teaching practices has been to
revise a lecture every year - even if he was
happy the way it went the previous year.
Severin said he was taught not co teach like
some professors, who use the same lecture
year after year.
"After doing that for five or six years, they're
bored - you can cell they're bored - and the
students are going to sense that as well; he
said.
Severin said he respected the efforts put in
by one of his own professors when he was a
student. "He spent a minimum of two hours
preparing each lecture after IS years."
As for professors who just read a prepared
text, Severin says, "that's not teaching. There
is no sense in coming co an 8 a.m. lecture if
the guy is just going co stand up there and
read.
"We both know it's readable. The object is
to try and get the student to remember it."
Often, after the lectures in which he
presents his tricks, Severin finds that students
present him with approaches they've devised
to learn the material.
"In effect, they are teaching me ways of
teaching."
•

BUFFALOPHYSICIANAND BIOMEDICALSCIENTIST

�People

:!J

sc1plinary
He ,~ d1rc1.tor of 1hc ~1ul11d1
and coUB
,II
Agmg
of
I~
Stu
the
for
Cenrer
d1rcctor of r '" \\ cm :-:c:."\\'rink Genamc
•
Educauon Ccmcr :it the Um\.-rsny.

M.D ., ho, lx·cn
Lebenthal,
:-.:anonal
,ttc:.
,.
[n,mute of Child Health and Human De
,dopmcnt rhat \\ 111re, tcw grant ,1pplicar1011s
involvmg nutm1onal therapy (or inborn
errors of mctahoh m.
Profc sor of pedrnm at UB, l..ebcmhal LS
..rologv and
, h1cfof 1ht•Ol\1,1011nt Gastroc:·111
:-.:um11011,tt ChtlJn·n's Hosp11al ,md J1rc:.'C•
tor of !IS lmernauonal ln,mu1c of lnfa111
:-.:um11on and Ga tromrestmal D1sca,c. •

Emanuel

hc r ry Leitch , a S&lt;.'tond-vearuuJrm. won a
n·lkl\\sh1p 1ha1
Tr.IV lcr Gcnamcs Rl.'5Carch
•
S3,000.
of
award
carries an

Trevor Litchmore , a third-year •tude111,
\\&lt;&gt;nan American Ht·art A&lt;so,1111on\ Stu•
Jent S.:holar,h1p m Ccrcbrova,cular Oisca c
•
thnt came,. an award of $1,'it"lO.
Edwin A. Mirand, Ph.D., J rc-ctor of the
Dcparrmcnt of Ec.lut,1t1onanJ dc;in of the
of UB, re•
Ro,\\cll Park Graduate D1v1s1011
A,,_,-ardm
\\ehr
H.
1lh
\X
Dr.
CCl\t-d the
M tr~h tor h1&lt;conmhuuom to Roswell Park
•
Memorial Im.mute.

Chc1rlt•\ Set•erin, Ph D
Ph .D ., meal mmucJudith Tamburlin,
tll&lt;&lt; , ,,on I L1llv
St
anntomKal
ror ol
n-llo"•h1p for her mno\'amc "hanJ,-on"
tt-achmg mcthcxh.
In a prQgr.!m mlcJ •Undcrgrnduate Human
An.11omv Dcmo11s1ra11on Lahormory and
RclmcJ Tt-achmg ~latcrial&lt;~ Tamhurhn ,,
ne:umg ,pcc1al materials for lnhorator\'
Jcmon&lt;1ramms h) prc,cn mg human 11--uc,
,uch a, hcan and lung , m a hfchke •cate.
This 1sdone chrough pla,1mauon, the prote,s o( rt·plauni: dw "acer Ill 11'-U&lt;"'"II h a
•
,iliu1111ypc ma1cri,1I.
0

0

John Acquavella, a Ph.D. tudcm m the
of Social and Pn:vcnnvc
Department
McJ1c me, rccc1vcJ the award for the best
pa~ pri:5ented on a di&lt;scrcauon m the :-:n-

BCHAI.O PHYSICIAS ,\SD lllOMEDICAI

uonal Compc:uuon of the
Ep1dcmiolog1t Rc~earth.

S.

ty

for
•

Ra)'mond P. Bissonette , Ph.D .. soc1me
tam1lv mcd1c11 ,c l B, was
,..._r
of the hoarJ oi dm."ttor, ol
idem
pre
dt-ctcd
1he Un11cd CerchrJI l'al y A ,oc1auon ot
•
'ri1rk, Inc.
\\b1crn :,.:&lt;"''
ob-,or and heaJ of
faan Calkin,, M.D.,
, anJ Gcromologv
n of Jcr
ch D,
:it UB, h,1, h,cn nanwd ,t ma,1.:r of the
American Colkgc of l'h\sitian,.
C-.alkms, chief of the Gcromolog~ cc11on
nt the \r\ Mcd1cal Cemer, wa, urcd for pron mcJ1&lt;:al
'1dmg d1rcc11on and 111&lt;p1ra11oco
,rnJcncs and residents and for hi, le;1Jcr,h1p
and '&gt;t!n,cc m rhe field of genamcs.

SCIESTISI

e prt..,.1dem for
John '\aughton, \1 0..
t c mcd1cal school
rs and d
cln
a1 UB, h," hct•n n.11ned pre,1dt·nt of I ht
Amcman Heart A~soc1,1tion,:,.:t"\I ); rk S1,1tt
,\ffihatc.
~aughcon ha, puhhsht-d c"renmdv on ex
t-rCN' and phy,1cal acuvnv m the prevcn•
•
110n "' c,,ronarv ht-:irt disease.
Tracy Perapato, 0.0., a th1rJ-vcar family
t Buffalo Gencr1I
med nt rc,1dcnt
Ho•pnal, 'J.On the annual ~c" ); rk Statt
Atadcmy of Family Prarnce Rcstdent A-1~arJ
•
for Rt.,.carth.
cudcm, won
arac , a fourth-war
Timur
!-1.'(lmdpn~e for h1~po,.tcr prt'!-1.'lllattona1 the
E,1,tcrn Srudenc Rest•;trch Forum 111 Florida
m

:',.1r h

•

EARLYWINTER l&lt;l~&lt;l

�Research

24

Surfactant Helps
Tiniest Preemies
UB researcher coordinates national study on IN FASURF

By ARTHUR PAGE

A

single dose of calf lung surfactant
extract. inJ_ected into their lungs ~t
bmh s1gmficanrly reduces the incidence and sevemy of respiratory distress
syndrome in premature and low-birthweight
infants, according to a national study coordinated by a UB researcher.
Involving 2,506 newborns eighr weeks or
more premature treated at 13 medical centers,
1t showed that the infants responded
favorably to a form of calf lung surfactant extract called INFASURF.
The most dramatic results were in the
smallest and most premature newborns, those
at greatest risk of developing problems.
Edmund A. Egan 11, UB professor of
pediatrics and physiology, said chat among
premature infants born 12 or more weeks early, INFASURF significantly decreased che
respiratory death race, incidence and severtty of acute lung disease and chronic lung
problems.
For example, the study included 712 infants
born 12 co 15weeks early, average birthweight
2 pounds, who received 100 milligrams of INFASURF at birth, and 96 infants who did
not. The incidence of severe respiratory
disease and respiratory death were halved in
the treated group.
Among the treated infants, 16 percent
developed severe respiratory disease and 8 percent died from respiratory failure, compared
to a 33 percent incidence of severe respiratory
disease in the untreated infants and a 19 percent death rate from respiratory failure.
"Current modification of the continuing

EARLYWINTER 1989

The ONY Company
was created to make
the surfactant
available even if it
isn't patentable.
study incorporates more than one dose oflNFASURF if a premature infant develops
respiratory disease even with treatment at
birch. This 'rescue' approach promises to further improve the outcome for these premature
infants; Egan said.
Respiratory distress syndrome, also known
as hyaline membrane disease, is a leading
cause of death and disability among
premature infants. le is estimated to occur in
50,000 of the approximately 250,000 infants
born prematurely each year 111 the U.S., k1ling about 5,000 of them. The third child of
President John F.Kennedy died of respiratory
distress syndrome in 1963.
Because of their prematurity, the lungs of
affected infants do not produce natural surfactant, a substance that coats the insides of
che lungs, preventing them from collapsing
when the baby exhales.
INFASURF is one of several surfactants

granted invescigational new drug (IND) status
by the U.S. Food and Drug Administration
and is being studied in medical centers across
the U.S.
The FDA in July approved making one of
these surfactants, a synthetic form manufactured by Burroughs Wellcome Co., available
for wide use prior co its receiving approval for
marketing because of surfactant's potential
benefit to infants born with respiratory
distress syndrome.
INFASURF and ocher surfactant macertals
arc still classified as INDs and cheir use is
limited to specific study centers. However,
their sponsors also arc seeking approval from
the FDA for wider use.
Egan and UB colleagues in the Division of
NL'Onatology at Children's Hospital of Buffalo and Goren Enhorning, M.D. and colleagues at Women's College Hospital in
Toronto first used calf lung surfactant extract
in the early 1980s. Carefully controlled
studies, reported in medical journals,
showed that injection of che calf lung surfactant extract protected tiny premature infants from respiratory failure.
The 13-center study conducted under the
FDA's designation of INFASURF as an IND
involves 2,506 infants to date.
INFASURF is produced by ONY Inc., a
Buffalo-based company of which Egan is
president. le wa~ incorporated in 1985 to seek
FDA approval for calf lung surfactant extract
for treatment of infants at risk for respiratory
distress syndrome because, according co Egan,
major pharmaceutical companies were not

BUFFALOPHYSICIANANO BIOMEDICALSCIENTIST

�Research

25

willing to sponsor ir because 1r was not
patentable.
"The pharmaceutical industry basically has
two issues in its product development or selection," Egan said. "One is that a product or
drug offer some benefit to people and the
other is char it make money for the company.
ONY was created to make this surfactant extract available to children, even if it isn't
patentable, because we believe it's the most
cffecti ve."
ONY is a "graduate" of the University at
Buffalo roundarion Inc. "incubator." The incubator was created to encourage development of small businesses in high-tech areas.
Its offices are located in Baird Research Park,
adjacent to the UB North (Amherst) Campus. Both the incubator and rhe research park
are managed by the Western New York
Technology Development Center.
•

RESEARCHERS
STUDY
COMPOUNDTHAT
Aas LIKEINSULIN

I

nsulin can be used co treat diabetes, but
how docs it work? UB scientists are trying
to unlock that secret by studying a compound called vanadate.
To many researchers' surprbe, vanadate, an
oxygen-vanadium anion, has been shown to
mimic insulin's acnons both in cells and in
diabetic rats. Insulin is a hormone rhat causes
body cells co take in glucose (a sugar) for
energy production and storage.
"When you have something that everyone
describes as insulin mimetic, it naturally leads
you to examine diabetes," explained Gail
Willsky, associate professor of biochemistry
at UB.
She recently received a grant from the
American Diabetes Association to investigate
vanadium's properties as an insulin ,mitaror,
yet Willsky's field of research is nor diabetes.
"I'm a vanadium person; she explained. "I'm
using rhe diabetes, in a sense, ro understand
how the vanadium compounds affect metabolism."
The similarity between vanadium's actions

stimulating a rt.-ceptoron the outside of a cell.
They act in much rhe same way as a key
opening a lock. Only a similar key will acnvate chat same receptor.
Once the receptor is activated, it will cause
certain other things to happen, like increasing glucose transport.
lnsulin is a long molecule, while vanadate
0
is much smaller. As a result, vanadacc can't
~
- fit in the same "keyhole" as insulin. Instead
it seems as if vanadate acts on a different Ioca'.
cion of the receptor.
•One hypothesis is thac it is stimulating the
~ protein kinase that's part of the insulin rccepcor inside the cell. Where insulin 1s binding
"' ac the extracellular, vanadium effects would
be intracellular: Willsky explained. Vanadium
would he tripping an internal latch of the
lock, while insulin opens the door from the
and insulin's came as a surprise LO medical
outside.
researchers.
Willsky said she is looking closely at how
"They not1ced in cell culture systems that
vanadium alleviates cardiac symptoms of
vanadace had an insulin mimetic activity,
diabetes in rats.
such as stimulating glucose transport; Willsky
"The heart, the kidney and the eye are the
said.
maJOr target tissues of diabetes," Willsky said.
Eventually, vanadate was med in animal
"I'm working in che heart w1th Robert J.
systems. "Ir wasn't until it was realized that
Mentzer (professor of surgery and physiology).
it had a lot of multiple hormone effects rhar
"With James Lohr (assistant professor of
it was tried m diabetic rats."
medicine) and Margaret Acara (associate proInsulin must be inJeCted, while vanadium
fessor of pharmacology and therapeutics),
can be ingested orally. Will vanadate ever
we're also studying how vanadium treatment
supplant insulin? Not likely, Willsky said.
alleviates kidney symptoms associated with
"I don't envision this in any way replacing
diabetes."
insulm. Since insulin 1s the body's natural
Currently, no drug company 1sinvestigating
answer to diabetes, 1t 1s the drug of choice:'
vanadium as an insulin substitute "due co the
Vanadate might be used to treat diabetics
face rhat it is so expensive" to meet Federal
who don't respond to insulin treatments, but
Drug Administration (FDA) guidelines for
that would be many years down the road.
drug approval, Willsky said.
"My efforts are focused on this very basic
science, the result of which could be used in
"The problem is the vanadium structure is
so ~,mple that they don't see how they can
a clinical setting," Willsky said.
The vanadium compounds may cause
maintain their rights to 1cafter they've gone
stomach problems and may make people who
for FDA approval. That's what I was told by
are hypertensive (prone to high blood
research and development people in the drug
pressure) even more hypertensive.
companies." As a result, Willsky said that the
"We're a long way from being able co predict
drug companies are afraid that they would
how a diabcnc would react to chis drug,"
not be able ro recoup their research and
Willsky said. "I think its higher potential is, development expenditures. However, there
if you can really understand how insulin
arc companies that are looking at vanadium
works, you might be able to eliminate
as a tool ro investigate insulin's activity, she
said.
•
diabetes some other way."
Hormones,
such as insulin, act by
-By David M. Smderman

BUFFALOPHYSICIANAND BIOMEDICALSCIENTIST

§

f

!

EARLYWINTER 1989

�Alumni

26

Medical Pioneer
Alumni Associationhonorsone of its own

A

m1.'Cl1cal
pioneer whose achievements
as clinician, scienrist and teacher have
spanned 60 years, George W. Thom,
M.D., was honored Sept. 21 as the first recipient of the Distinguished Alumnus Award
given by the UB School of Medicine and
Biomedical Sciences.
A 1929 graduate of the UB School of
Medicine, Thom 1scredited with establishing
the foundations of modem endocrinology
and metabolism and with pioneering what
1s believed co be the world's first organ
transplant as well as bringing kidney dialysis
to the United Scates. Thorn al'-0 initiated one
of the first "health plans,• a forerunner of today's group practices and health maintenance
organizations.
Thom received the award ar a dinner in
the Buffalo Club. Joseph L. Kunz, M.D., president of the Alumni Association, made the
presentation of a specially designed crystal
buffalo. Thom was introduced by John P.
Naughton, UB vice president for clinical affairs and dean of the medical school.
A professor emeritus at Harvard, Thom is
chairman of the Howard Hughes Medical Institute, which he founded with the late
Howard Hughes in 1953.The institute has
"expanded tremendously," Thom says, and
has developed a strong research program "in
40 medical centers throughout the country."
Thom is vice president of MIT's Whitaker
Health Sciences Fund and chairman of the
Whitaker Foundation's Scientific Review
board. A member of several visiting commit•

EARLYWINTER 1989

By JOAN DANZIG

A specially designed crystal buffalo was
presented to George W. Thorn, M.D.

tees at MIT, he is a life member of the corporation.
A Buffalo native, Thom's career as ~ researcher began while he was anending the UB
medical school. As early as his second year,
he began assisting Dr. Frank A. Hartman in
the preparation of adrenal extracts, developing the first workable assay for adrenal cortical extract activity. Thom looks to his work
in Buffalo as the start of one of his most
significant achievements, "the excitement of
developing the use of corcin for treatment of
Addison's disease which was an extension of
my work with Dr. Hartman at Buffalo.•
After graduation, he remained in Buffalo

for five years, first as a house officer at Millard
Fillmore Hospital and chen as assistant in the
departments of physiology and medicine at
the medical school.
In 1934, Thom was offered a Rockefeller
Fellowship, which cook him to Harvard
Medical School and Ohio Stace University,
where he rejoined Professor Hartman for one
year before leaving for Johns Hopkins
Medical School.
Thom became an associate professor of
medicine at Johns Hopkins in 1938.In 1942,
after service as a major in the Johns Hopkins
Medical Unit of the U.S. Army, Thom accepted an appointment as Hersey Professor
of the Theory and Practice of Physic at Har•
vard Medical School and became Physicianin-Ch1ef at the Peter Bent Brigham Hospital.
His life-long interest in renal disease
brought the pioneering dialysis techniques
developed by Kolffin the Netherlands to Peter
Bent Brigham, where, under his leadership,
the now world-wide standa rd procedure of
dialysis was put into use. His successful work
cleared the way for the development of a program of kidney transplantation. High on his
list of lifetime achievements, Thom says, is
"the unique experience of developing the artificial kidney for kidney dialysis.•
He was appointed Samuel A. Levine Professor of Medicine at Harvard in 1969. At
Harvard, Thom initiated the Harvard-MIT
Program in Health Sciences and Technology,
which culminated in the Whitaker College
of Health Sciences.

BUFFALOPHYSICIANAND BIOMEDICALSCIENTIST

�Alumni

27

A recipient of many national and international awards, Dr. Thorn received the
American Medical Association's Gold Medal
in 1932 for his work with Professor Hartman
on cortin and again in 1939 for his studies
on
desoxcorticosterone
and
pellet
implantation.
In 1946, UB Chancellor Samuel Capen
paid tribute to Thorn as a "leader ... master of
the arr and science of medicine" in awarding
him UB's Chancellor's Medal for "eminent
services in the alleviation of human suffering which have won for you high personal
distinction, and through you, have dignified
Buffalo in the eyes of the world."
A teacher of distinction, Thorn has had a
major influence on medical education, particularly during his years at Johns Hopkins
and Harvard, \\'here he trained more than
5,000 medical students.
Most medical students "know" Thorn,
though they may not have mer him, sweating

CALLFORNOMINATIONS

J

Immediately
above,
Dean John
Naughton, left, and Alumni President
Joseph Kunz, right, congratulate Dr.
Thorn at the dinner.
their way through the "Bible of Medicine,"
Harri.Ion'sPrinciplesof lncemalMedicine, which
Thorn edited for 31 years. One of its original
editors in 1946, he served as chief editor of
the 1977 edition.
•

BUFFALDPHYSICIANAND BIOMEDICALSCIENTIST

unc I is the deadline for nominations
for the second annual Distinguished
Medical Alumnus/a Award.
The award is presented to a graduate of the
UB medical school who has distinguished
himself or herself nationally or internationally in the eyes of his or her peers and has made
an oursranding contribution to medicine, the
arts, or humanity during his or her career.
The selection will be made during the summer and the award will be presented in the
fall at a special dinner.
Please forward the name of your nominee
as soon as possible on the attached postcard.
Your cooperation is viral if this is to be a true
alumnus / a award.
The 1989 winner is George W. Thorn,
M.D., a medical pioneer whose achievements
as a clinician, scientist and teacher have
spanned 60 years.
•

EARLYWINTER 1989

�Alumni

28

SPRINGCLINICALDAYAND
REUNION
WEEKEND

T

he graduates of the UB medical school have won
their share of local, national, and international
awards for achievement, but it took an enormous
amount of effort, toil, and sweat. Wouldn't it be nice
if, just once, someone gave an award for something
easy, like going to a party?
The Medical Alumni Association is doing that for
the first time at its reunion weekend. The reunion class
with the highest percentage of attendees will win a
trophy engraved with irs class year, which will be
displayed in the medical school.
Now, don't let the daces throw you. The next Spring
Clinical Day and Reunion Weekend will be held in
April, not May. It starts off with a cocktai l party Fri•
day evening, April 27. Spring Clinica l Day will be held
Saturday, Ap ril 28.
Arnold Reiman, editor of the Neu: EnglandJournal of Medicine, will deliver the Stockton Kimball
Memoria l Lecture.
The theme for Spring Clinical Day is "Changing
Aspects of Medical Practice~
•

Class of 1940

Class of 1945

Class o 1955

"Saturday,April 28, 1990,
the evening we hat·e all
waited 50 )'earsfor. Let u.s
make it our best reuniondetails lacer."
William Hildebrand , Jr.

"45 )ears! Tempus fugit.
Time co renew, time co
refreshold friendshipsand
memories from the most
significantyearsin our lit·es
- the Class of '45."
Herbert E. Joyce

"We are lookingfor a big
turnout for our 35th reunion. Plan now to meet
with your classmates."
James R. Nunn

Class o 1950

John A. Winter

"Togetherwe canmake our
40th a real winner. Lookingforu:ardto seeing)Ou all
in April."
Ro bert J. Patter so n

EARLY WINTER 1989

BUFFALO PHYSICIAN AND BIOMEDICAL SCIENTIST

�Alumni

29

Class o 1960

Class o 1965

Class o 1970

Class o 1980

Class o 1985

"It is with a great deal of
pleasure and anticipation
chatwe lookforu:ardcoour
30th reunion. Near coca!
parcicipacionu:ouldbe an
added bonus."
Roger S. Da yer

"Come cosee hou· we, the
school, and Bt1ffalohat·e
changed in 25 "ears. \\1/e
u:ot1ldl0t·e co hat·e :,ou in
Buffalo."
Joseph G. Cardamone

"You can't ignore20 :ears.
Step back into the pascand
reneu·friendshipsfrom chat
hapP) ume. Duse off ,ot1r
memoriesand bnng chem
along. Come back co
reminisceand share some
lat1ghs."
Donald P. Copley

"BAMMO! Ten:-a:11:1
hate
gone Ir:,·.Let's gee together
and .1eeif che chemiscryis
the same."

"Lee'sget rogecher
and auch
up on uhac'shappenedin che
lase/ite )el!TS."
John E Coyne

Margaret Paroski

I
Jame s R. Kanski

Robert M. Moskowitz

Class o 1975

Theresa Stephan Hains

Joseph A. Zi.zzi

"I 0-:,earreunion «:asgreac.
15 will be et·en better. See
)'OU acSpringClinicalDa:,
m Buffalo."
Jack Cukierman

BUFFALOPHYSICIANAND BIOMEDICALSCIENTIST

EARLYWINTER 1989

�Medical School

30

LIGHTINGUPIN STYLE:
LIBRARY
CHANDELIERS
AREANTIQUETREASURE

0

nee they glittered above nights of
music-making in a fabled Buffalo
house. Now they shine above studems
and researchers poring over books in the
Health Sciences Library.
Located in rhe HSL:s main reading room,
the restored twin antique chandeliers are
believed co dare from the 18-¼0s.Robert L.
Brown, M.D., associate professor of medicine
emencus and a member of the medical
school's class of 1944, made the restoration
possible through a donation to the UB
Foundation.
The silver-placed fixtures came to che HSL
as pare of the original furnishings of che old
Lockwood Library, which was opened in 1935
and was designed by Edward B. Green, also
the architect for the John J. Albright house,
a huge Tudor mansion on West Ferry Street.
These chandeliers once dominated the
Albrights' music room, but were moved in the
1930s when che Albright estate was broken
up, after the family suffered financial reversals. Originally candle chandeliers, they were
electrified when brought ro the old
Lockwood. The mansion, built at the cum
of the century, was torn down in the 1930s.
Albright, a pioneer in the development of
electric power and automobile manufacture,
gave more than $1 million for the construction of the Albright Art Gallery. While hardly a Morgan, he was, in che words of his
grandson, "symbolic of the day~ of the city's
greatness."

A donation from Robert L. Brown (M'44)
made the restoration possible.

buildings, was responsible for moving the
chandeliers out here; said Brown. He added
chat when the old Lockwood Library was
rehabili1tated as part of che Health Sciences
Library project, "there was no provision for
che restoration of the chandeliers. There was
even a question whether they would rehang
chem, 01rif they did, whether they would electrify chem. By chat time, they were black from
age:'
Brown, who 1salso che medical school's archivist, wanted to preserve these elegant
reminders of the old Lockwood.
"After· the library occupied the space, I
started making inquiries about having chem
restored, but che problem was chat no placer
had facilicies co cakc care of :.uch large pieces;
he explained. "We also would have had difficulty lnnding someone who would do the
rest of the restoration.
"Bue as a result of the restoration of the
Bueler Mansion downtown, I called the man
n 1934, a reporter for rhe Buffalo faening who did their major chandelier. I also located
Neu,~described the house's sad end: "l..cav- Marlette Placing, a local firm chat does coming the house, the visitor carries with him a mercial plating." Finding Marlette was a big
reverence which is as melancholy as the place advantage since the firm, headed by Edward
itself in the face of rhe dissolution it is Marlette, had the large placing baths needed
undergoing .... He (Albright) gathered the
for the job.
beautiful things of rhe world around him and
his aestheticism overflowed to give the dry
orne idea of the chandeliers' value can be
1rs noted temple of arc."
surmised from the pre-restoration ap"We assume that Green, who designed both
praisal.

I

S

EARLYWINTER 1989

"Wewanted insurance when che chandeliers
were being taken down; said Brown, "while
they were off che premises, until they were put
back up, that is, for che duration of rhe
restoration. They were appraised at $25,000
apiece."The value, of course, "is way up now."
Beyond moneta ry considerations, however,
was a reverence for the University's past.
"We were all concerned about preserving as
much as possible of the old Lockwood, which
was really an elegant building, the best the
University has ever built. The craftsmanship
couldn't be equaled today and it would be
unaffordable if it could be," Brown said.
"Our concern was co preserve as much as
we could, and the chandeliers were a significant part of chat main reading room. I wanted
to restore them co a scare chat they were
ongmally in."
In a charming comc1dence, the mother of
Edward Marlene's wife, Norma, was the
longtime assistant ro Charles D. Abbott,
director of University Libraries from 1934 to
1960. Her name was lvah P. Sweeney.
The restoration work was done by Jack
Kiener, a highly-regarded craftsman who has
been restoring antique lamps for 17years and
is the owner of Antique Lighting in Clarence.
"I'm quite sure these chandeliers are
English; said Kiener. He noted, coo, chat the
chandeliers have hcen kept together from the
beginning, an unusual occurrence in the
chandelier world.
He explained: "Every piece chat's removable
is numbered . Every arm has its spot to fir in.
Each piece was made by hand and made for
its O\\'n counterpart.
"When we disassembled the fixture, there
were 20 arms. On che number I arm, for instance, we have a bobeche, a candle cup, and
some finials. All are numbered so that they
fie back on number I. The numbers are
scamped m. Whoever made the fixture
numbered them in; this is the mark of a good
craftsman. Nothing is interchangeable:'
The arms on one chandelier are numbered
I through 20; the arms on the ocher are
numbered 21 through 40. "Sosince the 1840s,
the fixtures have stayed together all chis time;
he said. "This is very unusual."
It cook Kiener "close ro 90 days" to com-

BUFFALOPHYSICIANAND BIOMEDICALSCIENTIST

�;\fedical School

31

- --- ..---=

------- -=-

unrestnued endowment to help meet uncx•
peered financial needs and opportunities.
Accordmg to Prc,1Jenr Stewn B. Sample.
"The S5Z million \qll enable L'B to meet
needs char have been identified a, cr1ucal ro
the growth of rhe Untvcrsiry, hut for which
t.lte funds arc limacd or una\ailable.
"State budgetarv Imes cannot meet all rhe
needs of the University, nor can they provide
the flex1h1hrvchat i, ahsolutcly csscnrial for
rhe U111vcr,1rvto rhnvc. Joining pm·atc support w1ch~rate dollars will permit the Umvers1tv at Buffalo ro achieve its go,11of bccommg one of the nation•~mp ten public rl"5Carlh
uni\'er--iucs bv the end of the ccnturv."
The St hod of Mcd1e1nc and Biomedical
Soence, ha, received some of the largest gift,
co the campaign rhus far. Ont of the mo,1
rl'CCntwa, a $1 million l;,mmitmlnt from the
The chandelien once graced the ,\lbnght Mamion.
James H. Cummmg, Foundation, Inc. ro
rhe
of
assist m the funding of a Positron Emis.,ion
dav,
glorv
the
n:calling
One writer,
plerc rhe work on the first chandelier. "This
(PEn lrnagmg Cc111cr,a joint
Tomographv
the
remembered
mansion,
Alhright
involved preparmg ir for plating and
med1&lt;al slhool and the VA
thi:
of
project
her
m
husr
to
l1h-d
Albright
Mr;.
•mu"lalc,,"
reassembling 1r, ,rraighremng all the arm,,
Medical Center. This 1,1ranris the largest ever
mu,1c room. This was rhe "golden age" of the
rewiring it, lacquering it. Also, because 1t wa,
awarded m rhe 26-\·ear hi&lt;torv of the Cumhouse, he ,aid.
a candle chandelier, we had ro devise ,ome
mmgs fuundar1on.
ch.mdcl1er,,
rhc,e
that
One like,. ll) chmk
way of holdmg the ~ker, m and \\e handOcher significant rnnmbutions mdude a
renewed
found
ha\'e
shadow,,
the
in
so long
shaved wooden plug, to fit mro the candle
of ,ecurmcs valued at nearly 53 million
gift
•
home.
UB
their
in
glory
socket,."
a ml'OI&lt;11school alumnus who wishes
from
\\"h11chcr
Ann
B,
--ctfor
"wa,
chandelier
\1an,1on
The Burler
anonvmou&lt;. This i, the larJ:esr gift
remain
co
elecrric1rv." Kiener commented. "At l.iB, \\e
md1\1dunl ever rcn·1\·ed in the
l1v111g
a
from
had ro put the wire on the outside of rhe fixU111\'er,1tv.both a, a private
the
of
h1,rorv
er
,1h
wa,
that
ture. Ir's a solid c:&lt;1,tfixture
according to Jo,eph
msnruuon,
puhhc
and
w1rcwav,."
no
\\ere
e
plart.-d.Ther
the Uni\crsirv at
of
president
J. \lansficlJ,
fur the expcriencl-d Kiener, the UB proJclt
he used to
will
It
Foundation.
Buffalo
brought its own reward,. "le\ inspiring when
to help
endowment
unrestricted
an
e,tablish
wnR-d
vou on rake ~mething frc.,munre,.to
he. Unt\'er,1rv ar Buffalo Foundano .n's
nc\\
rl-cru1t
,cholar,hips.
,rudenc
pro\'1de
has
\\a&lt;
It
ampaign
black.
pach
wa,
GR'3tnl.._s•C
le
ro
1t.
fim,h
"Pathwav&lt;
and
dinon
rcchno)Ojly
high
purcha,e
mcmbcrs,
faculty
million Ill gift,
ratscd more than ..,z1.z
nor taken care of hccau,e of how high tt wa,;
equipment and support various needs of the
and pledges as of Sept. 15, according to
no one could keep it up, and it was ht·avily
R. Knox. national campaign medical ,-chool for wh1lh other funds arc
coated with lacquer and ~arni,h (applied) 111 ~onhrup
limited or una\'a1lablc.
,av
would
1c.I
.
prescne
cha1rpcr-,on Knox, who 1sLhairman ui rhe
hopes char thi, \\OUIJ
Another anonvmou, SI million !!!ft ro
hoard of !lilarinc Midland Bank, ,aid this
that 40 of the hours were ,pent just ,mp' Pathw;w, to Greatness' C-impmgn was
the
represents more than 40 percent of chc ramping the lacquer off the 20 arms."
for rhe Slhtol of ~fodK1ne.
dc,11:natt.-d
goal.
m1lhon
pa1gn'&lt;five-year, 552
The refurbished chandeliers alR-adv arc colthe ded1~Jt1on and lcaJcr~h1p of
"Through
Lampa1gn
the
,1fter
19~i.
day
next
0-.robcr
m
very
"The
Launched
leccmg rave review,.
and members of rhe Cam•
Knox
Northrup
,eeks ro increa,c permanent endowment
the first chandelier was inscalll-&lt;l;said Histtiry
we an· well on
Commmee,
xecutl\'C
E
pn11,?n
funds for the U111\'ers1tvtO pro\'ide pmfc,'-Or•
of \fod1cmc Librarian Lilli Sent:, "one of the
uhiect1\'es,"
our
achic~mg
tL
wav
our
(cllowsh1p,,
po,tgraduarc
,1nJ
,h1~. graduate
mamtenancc men who hod been 1molvcd
re is snll much co be
noct.-d."The
:-.tansfield
grantsarhlcti&lt;
holar,h1p,,
s,
e
sra1r,,
undergraduat
the
up
running
came
w1chthe hanging,
Jone, bur we arc confident of attninmg our
111-a1J.fine an, programming, aJJ1riom to
saying, 'I've got to see that chandelier: Th,tt
•
and
has been the reaction of the ,cudcnt,. roo." library and pocrrv/rare hook collccnons.

TOGREATNESS'
'PATHWAYS
TOPS$21.2 MILLION

T

BUFFALO PHYSICIAN AND BIOMEDICAL SCIENTIST

�Medical School

32

VAN RIDESFASTTRACK
FORCANCER
EDUCATION

W

hile black and Hispanic women have
a lower incidence of breast cancer
than white women, they are more
likely to die from the disease, according to
Noma Roberson, director of community in•
rervention and research at Roswell Park
Cancer ln,tirute.
One reason for the higher death rate among
these women is that "they tend to get into
the health care setting only at a very late stage
of the disease," she explained.
To get minority women into this semng
sooner, Roberson has developed a mobile
health care program. It operates from a
34-foot recreational vehicle which has been
renovated to include examination and
counseling rooms, along with a library and
classroom.
The transformed RV, which has been
named the "Health Express," travels around
Erie County bringing health education
and disease-detection services into poor and
minority communities.
Roberson, who received a Ph.D. in experimental pathology with an emphasis in
epidemiology from UB in 1985, said she has
been interested since early graduate school in
"women who are underserved (by the health
care system), women who are hard to reach."
Her doctoral research at UB focused on the
specifics needed in breast cancer programs to
reach minoriry women.
After graduate school, Roberson continued
to be preoccupied with the problem of how
to reach poor and minority women who
might be at risk for breast cancer.
"Over the years,"said Roberson, "we've had
a number of programs chat have involved major recruitment efforts to get people to come
in to use the health care services at Roswell
Park. Yet while we've been successful, we have
not been as successful as I would like."
And then one day, "out of the blue," Roberson came up with the idea of a mobile van.
While there are other mobile health care units
in the country, the "Health Express• is unique.
"Most mobile units are geared to providing

EARLY WINTER 1989

Developer Noma Roberson meets the
press at the opening of the Health
Express.
X-rays,"said Roberson; "this one will not (pro•
vide them). Instead, it will provide the first
step - education and clinical breast examination.
"\Y/ewill emphasize the importance of early detection. The women will come in for a
45-minute to an hour program. They will
listen coa brief presentation and then actually
work with the breast models on a one-to-one
basis. They'll learn how to find a lump, see
what a lump looks like, what it feels like."
Besides learning how to examine their own
breasts, the women will also be able to receive
clinical breast exams in the examination room
of the mobile health care unit. According to
Roberson, "a nurse will check the woman's
breasts thoroughly to see if there are any problems. If there are, the woman will be referred
to Roswell Park or a physician of her chokc.•
At Roswell Park, Roberson continued, "a
physician will examine the woman even more
thoroughly and will make a recommendation
if there is a need for X-rays and further examination."
All of these services, the classes, the examinations in the van and at Roswell Park,
as well as Pap cests, are free, Roberson noted.
In addition, she said, the program will provide free mammographies for women who
lack insurance.
These women who fall through the cracks,
a situation which is more and more common,
merely must prove that they are needy and

that they are at least 50 years old. She added
that free mammographies mighc also be provided for younger women, depending on the
case.
"A 30-year-old woman whose mother died
of breast cancer, whose sister died of breast
cancer, and who now has suspicious findings
on her breast would probably be a candidate;
Roberson said.
Finally, to help women who have been
diagnosed as having either breast or uterine
cancer survive "the devastating rehabilitative
phase," Roberson said there will be a support
group and counseling program.
To gee the women to use the van, field
workers introduce rhe program to directors
of neighborhood centers or schools, then
work with the directors to publicize the van's
arrival.
The "Health Express" has been financed by
a grant of $205,190 for two years from the
New York State Department of Health. The
grant is part of a $1 million fund that was set
aside by the stare last year to develop brea,t
cancer detection programs.
"The intent for chat money; Roberson explained, "was to service the state by developing model programs that would focus on the
early &lt;leccction of breast cancer and that
could be used in the future across the state."
Of the eight programs awarded grants by
the Department of Health, Roberson said
hers is the only one that uses a mobile unit.
In addition to the grant from the Health
Department, Roberson has received services
from Roswell Park, and from various community agencies, including the Erie County
Health Department, Sheehan Memorial
Hospital, the American Cancer Society, the
Medical Society of Erie County, and rhe
Geneva B. Scruggs Health Care Center.
"As I add up the contributions of all these
agencies, including my own institution, we're
talking about a program that is really about
a $400,000 program, which we've done for
about $200,000.
"And that," Roberson concluded, "is just a
demonstration of the importance of community coalition for these kinds of health care
projects."
•

- By ElisabethSheffield

BUFFALOPHYSICIANANO BIOMEDICALSCIENTIST

�Briefs

33

SEMINARS
SET
ON THEAGING

A

series of faculty development seminars will be held by the Western New
York Geriatric Education Center and
the Multidisciplinary Center on Aging from
~bruary to April m Beck Hall on UB's South
(Main Street) Campus.
Continuing Medical Education credit of
category I (CME) will be given for each
seminar attended.
For more information, contact Patricia M.
Krupp, Beck Hall, 831-3176.

i

MFH OPENSCENTER
FOR
AMBULATORY
SURGERY

M

illard Fillmore Hospital has opened
the first multi-spccialcy, freestanding
ambulatory
surgery center in
Western New York. It's one of the first of its
kind in the State.
Located m Amherst, the center is designed to accommodate most types of nonemergent, uncomplicated elective surgeries.
le has the capacity to perform more than
7,000 procedures
a year, including
ophthalmologic surgery, breast biopsies, arthroscopic surgery, plastic surgery, hernia
repairs, pediatric procedures, and oral and
nasal surgery, among other types of minor
surgeries.
"le is estimated char by the mid-l990s, -15
to 50 per cent of all ,urgical procedures will
be performed on an ambulatory basis," said
Jared C. Bario", M.D., president and medical
director of the center.
•

~
A~lllllll~lf

should not only be checked by doctors and
nurses at the operating room door, hut removed before the surgical scrub, according to
Thomas S. Beam, M.O., associate professor
of medicine and microbiology at UB.
Whtie such mfccnons invariably arc
caused by bacteria colomzing the patient, rhc
source of infection of a wound may be questionL-d if surgical gloves tear during an operation. Stressing the payoff of an ounce of
prevention and noting chat removing a rmg
is a mammal inconvenience for most people,
Beam wrote in the Journal of the American
.'vledicalAssocwtionrhac the most prudent approach i, not to wear jewelry in the operating
room.
•

AN ONLYCHILD
OPERATING
ROOMIS
MAYHAVEHIGHER
No PLACEFORJEWELRYBLOODPRESSURE
Add co the long list of potential sources of
nosocomial infections chat band of gold on
a surgeon's ring finger.
Because it may harbor bacteria char can
trigger a postoperative infection, jewelry

BUFFALO PHYSICIAN At-:D BIOMEDICAL

SCIENTIST

A

dulcs who were only-children are more
likely to have higher blood p_ressure
than those who grew up with siblings,
according to a study conducted at UB.
The researchers found chat adults who were

iii

~

6

only-children had significantly higher mean
systolic and diastolic blood pressures than
those with brothers and sisters, regardless of
number of siblings.
The results were presented at the fourth
scientific meeting of the American Socierv of
Hvpertension held in New York Cicv.
Maurizio Trevisan, M.D., associate professor
of social and preventive medicine, said the
higher blood pressure found among adults
who were only-children could be responsible
in part for the finding ma ,eparate srudy of
a higher incidence of coronary heart disease
deaths among adults without siblings.
He postulated thar the higher blood
pressure m adults who were only-children
may be a consequence of stress resulting from
inLreased expectations placed on an onlv
,hild and/or growing up m a limited social
network due ro the lack of siblings.
The UB researchers investigated the rela•
tionship of birch order to blood pressure in
676 white males and 796 white females, aged
20 to 70 years, participating in che Buffalo
Blood Pressure Study.
•

§

ECMCOPENSCENTER
FORBURNTREATMENT

T

he Regional Burn Treatment Center of
Western New York opened in March ac
che Erie County Medical Center.
This is the culmination of a two-year planning process berween ECMC and Sheehan
Memorial Hospital, which closed its burn
service.
The medical director of the new burn
center is Jorge Rodriguez, M.D., who received
his training in the management of critically
ill patients at Columbia University and the
University of Louisville.
The center has eight beds: six for critical
care and two for intermediate care. The unit
includes cwo hydrotherapy rooms and scareof-the-art monitoring equipment, as well as
staff and family conference areas and administrative space.
Construction and renovation for the center
cost about $1 million.
•

EARLY WINTER 1989

�Classnotcs

34

held in Hyderabad, India.

Harold F. Wherley (M'36) • of
Stone Creek, Ohio, writes chat
his grandson Rob, (son of Benjamin J. Wherle y, M'65 } 1s
starting medicine at the Univer•
my of Cincinnati.

Albert P. Sutton (M'48 ) • pre;idenc of the New York Section of
che American Uro logical Association, organized the Annual
~ieeting held in Lausanne,
Switzerland, on Occobcr 22-29.

Matt A. Gajewski (M'39) • wa&gt;honored by t he Erit: County
L..-i::i,laturewhen tht:v named the
Human Scn1c1.:,Center on Buffalo\ East Side the "Dr. ~1att A.
St:n ices
GaJewsk1 Human
Center."

Harte)

C. Slocum '36

1920's
L. Maxw ell Lockie , Ph.G .
(M'29 ) • profe"or &lt;.memu, of
therapeuttc, at UB, ha, been
named to the prestigious rank of
"ma&lt;rer•bv the American Colk,gc
ofRheumatology. P:iruallvrenred,
he now serves as a consultant m
rheummology at t he Erie Counry Med1Cal Centl"r, Buffalo
General and ~1illard Fillmore
hosp1ral,, and Children\ Hospital
of Buffalo, where he founded one
of chi, country\ first clinic, for
children with arthriu,. During hi,
medical career he developed
method, of diagno,rs and treat•
menr for arthrms now used
world-wide.

1940's

EARLYWINTER !&lt;13Q

Andreu• A. Ga~e '44

Edward G. Forgra ve (M '45 ) •
informs us I hat he remed from acm·e practice m 1985,but i, still
doing somr UR work

of the Phi Lambda Kappa
Mc&lt;l1rnlFraternity, he was ell-cted
to the po,ition of \'ice chairman
of the board of the two orizani:anons. Dr. Levy is currently m the
Geo rge A. Poda (M'45 ) •
private practice of psychiatry m
reured aftt:r 381/z years as m1.-dical
Buffalo, chairman of che Depart•
of Du Pone's
,uperintcndent
ment of Psvch1atrv at the ~1illard
Savannah River Plant. He i&lt;no\\
Fillmore Hosp1tab, and a clmical
teaching at Oak Ridge A,,ouated
associate professor of psychiatry
Universine, and doing contract
at the UB medical school.
work for the Department of
Energy - "th1, 1s fun!"
Andrew A. Gage (M'44) • one
C arl J. lmp e lliti e r (M '46 ) • a
thoracJC 'C\ surgeon, Joined the
scaffof the M.iyo Clime in Scorudale. An:. 'Grear wav co cut
back on a surgical pranice. Heare
and hand arc still steady!"

Annabel Miller Iron s (M'46 )
• of Chevenr e, \\ vo., rctm.J 'rom
the Veteran, Adm1ni,trat1on
Joseph R. Saab (M'34 ) • of Hospital and 1s now doing
Hamburiz, N.Y., celebrated h15 \'olunrecr medical work in the
80th birthday m August. Dr. Veteran, Admm1stracion\ Nur~Saab rccentlv attended hi&lt; ;sch
mg Home. Dr. Irons 1, pre,1dent
class reunion .
of the Woman's Club of
Cheyenne, the oldest (201 years)
Harvey C. Slocum (M '36 ) • 1s federated cluh in Wvommi:;.
profe5sor emeritus of the University of Texas Medical Branch and
Harold J. Levy (M '46 ) • Afte r
a Colonel (Ret.) in the U.S. ,ervmg as president of the
Army. Dr. Slocum live, in San
Medical Student Aid Society,
Antonio, Texas.
which 1sthe ph1lanthro1 &lt; hranch

1930's

Paul T. Buerger (M'49) • of
Young,cown, ~ .Y.,writes, "I have
jomed the Anthropology Depart·
ment of SUNY as a graduate stu•
dent."

of the developer, of the implantable cardiac pacemaker, rClcnrly received two awards. Gage was
honored in March at the annual
meenng of the American Society
of Contemporary Medicine and
Surgery in Florida. In April, he
was honored during the s&lt;.'&lt;.ond
annual Thoracic Surgical Teachmg Days program, co-sponso red
by UB and Buffalo Genera l
Hospital. Gage is che deputy
director of the Roswell Park
Cancer Institute and a profc,,or
of surgery at UB.
Arthur J. Schaefer (M '47) •
delivered the fir,t Dr. P. Ramchander Memonal Oration at the
Annual Ophthalmolog ical Meet•
ing given by che Kanchan Eve
Hospital and &amp;-search Cente r

1950's
H e r b e rt L. Berman (M'SO ) •
has retired from the active practice of plastic and reconstructivc
surgery and is now r~iding in
Scocc,dale, Ariz.
Vict o r A . Panaro (M'52) • was
elected to the board of director,
of Blue Shield of W1.-scernNew
York and Community Blue and
serve, as a counci lor for the
American Coll~e of Radiology.
Roy J. Thurn (M'52 ) • wmes
"As a captain in the USP HS
Ready Reserve, I recently com
pieced a two week ,horc tour of
ducy at the Crownpomc, N .M.,
Indian Health Facility on the
NavaJo Indian Reservatton. It was
a very rewarding experience."

11
P. Hamilton
Thomas
(M'S?) • was recalled to active
duty by the Unaed Scares A rmy
in 1984 as deputy commander,
Center,
Army Aeromedical
followed by an assignment in
Saudi Arabia. He is currently
chief of the Preventive Medical
Service at Brooke Armv Medical
Center m San Antonio, Texas.
John B. Ander son , Jr. (M'58 )
• medical director for Centerior

BUFFALOPHYSICIANAND BIOMEDICALSCIENTIST

�Classnoces

35

pleasure: patients and che opportunity for flight time again. Also
appointt-d to che admissions committee, School of Medicine, uni·
formed Services University of the
Health Sciences."

Energy Corporation, ha, been
clencd president of the hoard of
trustees for the Andrew, School,
an independent girls' boarding
and day school in Willoughby,
Ohio.

1960's

Je rro ld D. Canto r (M'69) •
\\as ek"&lt;.tedchief of the medical
,raff , t C:ia,ral Communttil-,,
Hospital, Santa Ana, Calif.

Algirda s Gamziuk as (M'60) •
has been appointed ass0&lt;.iaceadministrator for medical affairs at
St. Joseph Ho,pital in Check•
towaga.

1970'.,
Seba stian Co nti (M'70) • has

Rob e rta M . G ilb e r t (M '6 2) •
was named ml-d1cald1rt-ccorof che
Georgetown University Family
Center. Dr. Gilbert presented a
Add1ltion,: Put
pap.:r "lat~cn
ting the Patient m Charge" at the
Midwest Family Theory Sympo,1um in Chicago.

Harold J. Le,,y '46

Rob e rt W. Hamilt o n (M' 63) •
ha, moved co Tc,k-do,Ohio, where
he 1, professor of mt•1.hcineand
chief of the ncphrology division
of the MedJl'll Coll~l' of OhK

England area in chc fall of 1989
after serving a, chief of the
ob/gyn department, Supreme
Allied Powers
Headquarters,
Europe (S.H.A.PE.). Belgium.

of both the American Lung
Associauon ofWC!SternNew York
and the ~ev. York Trudeau
Sociery.

Jeffr ey S. Ro ss (M '70) • \rntes
Ro be rt M . Tabac hn ikoff
"I have rl"\.Cnth·t-,.-ln apooinwd
(M'66) • returned co the :-,.:ew professor and chairman of the

Steph en C. Sc heiber (M'64) •
R a n da ll A nd e r so n
John
ha, been ele1.1edto Who'i Whom
(M '67) • wa, rt&lt;. nclv bo'lrd certhe \\'orld. He ,en·es a, eXl"CUtl\"C
in cmergcn1.y med1unc. He
secretary of the Ameman Board
of Psychiatry and Neurology and
president of the As.soc1auon for
Academic P,y&lt;hiacry. Dr. Scheiber 1, also a member of the
Award, Committee of the American College of P,ych1atri,ts.

Al an Saltzm an (M'66) • has
been named clinical director of
the Department of Medicine at
the Erie County Medical Center.
He is chief of the pulmonary
disease section and associate chief
of mc.-dtcal-.er-viceat the Buffalo
\½ Medical Center. Dr. 5almnan
serves on che board of che
Amencan Lung Association of
~ew York Scatt and is president

a pnv,ire practice ,11(:cializin~in
\"ascular surgcr\' and IS an
associate clmie.tl professor of
,urgerv at the Umvcr,uy of
California at Davi,.

tified
i, a clinical assistant pmfc,,or of
familv medicine at UB.

D av id Fuga zzo tt o (M '6 7) • is
part Jf a group pral CJ&lt;e in
ped1atr1t, in Birmingham, Ala.
Dr. Fugazmcco w;i, elected to the
executive committee at the
;\1ed1calCenter Ea,c Ho,paal.

Capt. Elias Rose nblatt (M'68)
• write!',"Just completed a tour as
director of medical services and
executive officer of the Naval
Medical Clime in Washm~on,
D.C. and have begun a clinical
position with the Naval Air Facil•
icyat Andrews Air Force Ba&lt;e.A

BUFFALO PHYSICIA:-: A~D BIO~EDICAL SCIESTIST

Department of Pathology at the
Alban\' ;\1t-dicalCenter Ho,p1tal
and Albanv Medical Colk-ge,
Albanv, N.Y."

Roy M. Oswa ks (M'7 l ) • was
elected c h1cf of surgery ac
Bayside,
Hospnll
Humana
V1rgm1a Beach, Va.

W illi am Hru shes ky (M'73) •
wnres, "Aftu a do.en years, t the
University ofMmnesota m MPIS,
I haw returned co ~cw York and
profe"&lt;Jr of
am currently
medicine and m1lrobiologyltm•
munobiologv at Albany }..1ed1cal
College of Union Lim\er,1tv.
While in Mmnc,oca I captured a
:--=orwegian Amencan pr~ncc,s,
Pamc1a A. \'food, \1.D., Ph.D.,
and we have recently had our first
M.uie
Cassandra
daughtl·r,
:-,.:1Cole.•

Melvin R. Pratter (M'7 3) • is
head of ch division of pulmonarv

John B. Anderson, Jr. '58
and cmical care and profe,,or of
Rohen
medicine ,11 UMDNJ
Sl hool of
\"food Johnson
;\1cd1cmeat Camden. Dr. Praucr
has two children, Chtusen, age IO,
and David, age 6.

Michael Row land (M'75) • is
president clelt of the North
of the
Chapter
Carolina
Amcncan College of Surgeom
and was also clccced into
of the ~orth
membcr,hip
Carolina ':,urg1calA"oc1ation, a
group limited to a maximum
membcr,hip of 100,urgcons. Dr.
as chair•
Rowland currently scrv&lt;.-s
Commmee
man of the Cancer
and Outr, atienc Commmee at
Hospnal.
Regional
~loJre
Pinehurst, N.C.
Na n cy H .• ie lsc n (M '76) • a
'fX"(talisc111 internal ml-dicincand
infcccious d1sc3ses, is the new
president of the ;\icd1cal Societv
of the Countv of Eric She is the
first woman 10 lead the organtza1 'on in 1t, 165-vear history.

Kev in C. Gree nidg e (M'77 ) •
1s currently an associate professor
of clinical ophchalmologv at the
~e\~ York Medical College and
lhtef of the Department of
Ophthalmologv and director of

EARLY Wlt-:TER JQ8Q

�Classnotes
&amp; Deaths

36

from che NIH in support of my
research on hepatic glucose
metabolism. Paula and I now
have cwo children, Isaiah, 8, and
Steven, 3."

He served four years in the U.S.
Army, entering as lieutenant and
bemg discharged as major. He
spent 28 years as an instructor for
surgical technicians and served
with the 96th Field Hospital in India and China.

Walter R. Siemien (M'80) • of
Winter Park, Fla., is certified hv
che American Board of Plastic
Surgery.

Thoma s J. Sy racuse (M'33) •

James F. Twist (M 'SO) • has
moved his office for the practice
to
2156
of ophthalmology
Sheridan Dr., Kenmore, 1'!.Y.

Nancy H. Nielsen '76

Jack Hajjar

'85

D eni se M. Goo dman (M'83) •
glaucoma services ac Metropolitan Hospital Cencer in New York.
He recently had a book chapter,
"Head Pain Associated with the
Eye,"published in Managemencof
Facial, Head and Neck Pam,
published by W.B. Saunders
Company, Philadelphia, 1989.

wrnes,
"After
completing
pediatrics at CHMC Cincinnati
and a critical care fellowship in
Pittsburgh, I am now assistant
professor of pediatric critical care
at the University of Minnesota,
and I practice at the University
Hospical."

Jo n ath an H. Woo dcoc k
(M '77) • has been appointed

Eri c P. W ittkug el (M' 83) • has
completed
his training
in
pediatrics, anesthesiology, pediatric ancschesiology, and cncical
care at che University of Pennsylvania and the Children's Hospital
of Philadelphia. He is currently an
assistant professor of clinical
anesthesiology and pcdiamcs at
the University ofCincinnaci and
the Cincinnati
Children's
Hospital.

medical director and clinical
leader of the Neurobchavioral Inscicuceof che Rockies in Louisville,
Colo.

Roge r Kaiser (M'7 9) • has
been named clinic:JI director of
anesthesiology at the Eric Coun•
ty Medical Center.

1980's
Eric Ten Broc k (M'SO) • has
been appointed director of Pulmonary Funccion and Blood Gas
at Buffalo General Hospital. He
is also director of the Medical Intensive Care Unit at BGH and
assistant professor of medicine for
the Division of Pulmonary and
Critical Care at UB.
Robe rt Sha lwitz (M'SO) • of
Creve Coeur, Mo. writes, "I was
recently awarded a FIRST grant

EARLYWINTER1989

Jack Hajjar (M'85) • writes,
"On Dec. 13, 1988, I left for the
earchquake-devascaced region in
Soviec Armenia wich an ICU
team from Montefiore Medical
Center (where I am doing my
fellowship in anesthesia) sponsored by the State Department.
The team participated in rescue
efforts and worked at the
Republic Hospital, the largest in
Soviet Armenia. We equipped
their ICU with $1 million worth

of equipment donated by several
industries." He went back to
Armenia in April co scare a longterm training and exchange program in order to establish a fully
equipped ICU Departmenc at the
Republic Hospital.

a member of the UB Athletic Hall
of Fame, died Feb. 26. He was 79.
As an undergraduate at UB, he
was a member of the undefeated
1930-31basketball team. He lacer
cook up golf, winning the Erie
County Medical Society championship.
Three years ago, he retired after
practicing medicine for more than
50 years.
Syracuse was a member of the
UB Bison Head Society and Erie
County Medical Society.

Abrah am S. Lem:ner (M '41) •

Deaths
Marvin A. Bloc k (M'25) • a
retired clinical assistant professor
of medicine at UB who was a
pioneer in persuading physicians
to treat alcoholism as a disease,
died Feb.28 in Buffalo at the age
of 86.
Block wrote widely on alcohol
abuse and addressed groups
throughout the world.
His efforts led co the 1956 vote
by the AMA House of Delegates
co declare alcoholism an "illness"
and to urge doctors to treat its
"victims."

Ronald Walt er Steub e (M' 3 l )
• died July 9, in Naples, Fla.

Jo hn Ca lvin Inman (M '33) •
died July I, 1989. He was on the
staff of Mercy Hospital, Lake
City, Md., for 40 years, serving as
chief of surgery and chief of staff.

died in June 1989 of heart failure.
He served in World War II from
1942 to 1946 as a lieutenant commander, MCUSNR in the Pacific
Theater. first as a Seahce, then
aboard LSTs. He received eight
major campaign scars and a Purple Heare.
He was adjunct professor of
clinical psychiatry at the Dartmouth
Medical School,
a
member of the psychiatric staff at
Mc. Ascucney Hospital and
Health Center and served on the
Commiccec on Aging of the Vermont Scace Medical Society.
In addinon to his pnvate practice in psychiatry, he devoted
suhscantial voluntary time locally and nationally to the growth
and development of psychiatry.
A pioneer in methods of outpatient care and the treatment of
psychosomatic illnesses, Lenzner
was a Life Fellow of the American
Psychiatric Association.

BUFFALOPHYSICIANAND BIOMEDICALSCIENTIST

��~oo-Prof1 Ori;
L, Po.ta

Buffalo Physic ian &amp; Biomedica l Scientist

PAID
Buffalo,NY
1\-rm t =-- lll

State Untvers,ty of New York at Buffalo
3435 Main Street
Buffalo, New York 14214
Address CorrKtlon Requested

3 581
DR L. MAXWELLLOCKIE
925 DELEWAREAVE
BUFFALO NY 142 0 9

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                    <text>\ol. 24, !'-:u.I

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DearFriends:

Nann Tol•n

T

he current ,.,,,uc of the Ph'ljs1cranmc.luJcs ,m .,mdc det,111
mi: the &lt;,1rccr ,uu:e,~ ot three ,1lumnt ,, ho ,ire me&lt;l1c.,1l
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on reuunment , t faLuh, ,, uh rec.ord, , f Mgnthc.mt ,Khre\C
mcm Also., p,m of 1h.11t,ISk is the de,elupmt'nt 111mdr\"lduab
who rcpn·wm Buftal1),II ,&gt;1hcrqualny m,111u1101iThe thrtt mdr, ,duals pr. filed m&lt;lccJ rc.-presem the be,1 m
tC"rm&lt;uf J'C'r.&lt;n 1I md pr&lt; fc ,ron 1I , ,luL,, wrecr pr,&gt;ducu, II\
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tel1 gramudc tor commntmi: their hH"li tu purp&lt;™-"li
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so dear

EPIT\ R
C.inn1c (.),,.JIJ 'I ,tl

ART DIRECTOR
AbnJ Kr,:lcr
\\ RITI RS
D.i, iJ I limmcli:rttro
Anhur r'I:'"
Jdtm. Tr,M,
"U&lt;'\luctchn

r1tun X,RAl'I lERS
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Rot...-rt'iJ.

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AO\'J-.;()RY BO .\RD
Dr John N ,u •hhm, l h.:unnan
Dr II ,IJ Br~
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"""''(,I«'

Dr J

K.nd,
Dr J,...,,h L Kur

Dr Ch irk r, mdl,
M• I Jul () l'dl&lt;n&lt;•n
Dr !\nt
It&lt; rcren

Dr ( hark, rnrr

Dr Luther R &gt;hn

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\'rec l'rts1d..•mfarClinu-alAffa,"
Dean, Schoolof i\fofu.11\t'
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Dr J.-r.....,YJ10

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SrrinK 1990, \, 1 umc 24 Numl,cr I
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DearColleagues:

I

I \\ould lakC"to ,h re "uh }OU ex1..crp1, from I IC"ttfr "c
r«cl\cd from I m1.'tll~r, t the i:raJuJtmg c.Li, th,mkmi: us
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our ,1lumnt ,ire trul\ mtcrcstcJ m the ,tud1.-nL, mJ the ,;chool
11,clt ~I.mi ,1lumrn ,1ss,x1,111o
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alma m llt'1' h\ m ,kmi: ml•ne1,11; Jon 1110n, to the ~hool md
c-.1,1hlt,hmi: ,m 'olJ h.,) ncl\\Ork' for gr,1duates. \Vh1le 1he-e ue
clfecme mJ o.ll.'-ept.IMCmethoJs,
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our lumm h,tH dim.en to h.•
more J1redh 1mohl..J.
"Through the -.enior rccepttun, the ~pnng Clmrc. ,I n.i, an,1
m,m\ oth,•r ,1lumnt ,1ff 1rs, \OU h,1H· set ,m ex mple for u, ot
hlm our ,,lumnr .1ssoc1a11unc.m be "hen 11c..ircs to go furthl·r
th1n tht· 1r,1d111on,1,ICU\
I
11,e,. 'wur J&lt;.11\CpnJc ,md concern
c.h1llenge, u&lt; to hcconw 11:u,e ,1lun1111
.md contmuc 10 ,!um
the s..hool .md the communn, \,h.11 "1mport,mt 10 rh,,1u.in,
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Pusidenr, 1',itdirolAlmmuAssoc1a1on

�Vol. 24, No. I

Srrmg 1990

Research
briefs.Sodium and stomach cancer; elderly blacks need more health care; soaking in the
tub; healthy wheelchair ; active endothelium.

Onpinsandneedles.It's not until everything else
Pinpointingpain relief,
page6.

has failed to relieve their pain that patients tum
to acupuncture and UB's June Oh, M.D.

Theboywholiveda miracle
. No one had ever recovered from such an injury. But Brian Fitzpatrick, a
1986 graduate of the UB medical school who
helped treat the boy, was able to see him walk out
of the hospital.

Microscopes
to microchips.
From practicing diagnoses
The caseof ihe "miracleboy," page 12.

to recognizing heart murmurs, computers have
emerged as the UB medical schoo l's newest teaching tool.

Moreresearch
. A major study suggests that olive oil
is more "heart smart" than butter and another
project investigates temporary shelters for the
homeless made of corrugated cardboard.

Talentintriplicate.
UB boasts three alumni who are
currently medical school deans. Take a glimpse at
their careers and their recollections of UB.

Alumni.
A member of the Class of 1971 honors a
teacher through a gift to the UB medical school
and two members of the Class of 1930 are remembered through gifts.
Computers:the UB medical school'snewest teaching tool, page 18.

Classnotes
.

Cover:Illustration
by John Ripa
UB boasts three alumni who are
medicalschooldeans, page26.

�---

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SODIUM
INTHEDIET
MAYINCREASE
THERISK
OFSTOMACH
CANCER
t's prohably not good fnr your heart,
and now 1t looks like higher levels of
sodium m the diet mcrease the risk
of gastric, or stomach, cancer, according
to a ~tudy by researchers al UB.
They found a dose-response increase
in risk for men and women related to
sodium, as well as related to fat and
retinol, a form of Vitamin A.
Puhlbhed in Nutrition and Cancer,
the study of diet in the ep idemiology of
gastric cancer was conducted by Saxon
Graham, Ph.D., professor and chair of
the UB Department
of Social and
Preventive Medicine, and colleagues.
Based on extensive interviews with
293 patients with gastric cancer and
carefully-malched controls, It showed
"suhstantial reductions in ri,k were
associated
w1th
111gest1on of
carotene ... as well as with increased use
of low-temrerature food storage."
Vegetables, some nf them rich 1n
carotene,
identified
by the UB
researchers as decreasing nsk were celery, cucumhers, carrots, green peprers,
tomatoes and oniom.
Noting that the incidence of gastric
cancer has dropped "drastically" in recent
yean., the re-earchers sa1J "the promulgation nf preventive medicine recommendation.-,is less urgent than formerly.
"Certamly, however, limiting caloric

intake, especially fat, limiting sodium,
and increasing intake of vegetables, particularly those containing carotene, are
suggested as steps in the direction of
inhihiting nsk of stomach cancer. The
same may be said for use of refrigeration .
"A number of other cancers, such as
cancer of the colon and lung, as well as
cardmvascular pathok1gies, might also be
controlled by these dietary suggestions."
The UB researchers found a doseresponse increase in nsk with increases
in ingestion of total number of calories, as well as total carbohydrates, fats
and protein.
"Consistent
wnh our finding of
increased risk associated with fats and
protem, was an incrt::ase in risk associated wirh increai-es in ingestion of
meats," they said.
The researchers also noted "a numher
of high-search foods were associated
with increased mk of gastric cancer,
including potatoes, potato chips, french
fries, pe;u;, nee and pasta."
Graham said improvements in the
refrigeration of food since the early
1900s may be a maior factor in the drop
m gastric cancer.
"Both refrigeration and carotene
could inhibit oxidation products which
could act as carcinogens 111 the stomach," the researchers noted.
Other UB researchers participating
in the study were Brenda P. Haughey,
Ph.D.; James R. Marshall, Ph.D.; John
R. Brasure; Maria A. Ziele:ny, Ph.D.; Jo
L. Freudenheim, Ph.D., and James P.
Nolan, M.D. Also authors of the paper
were Dee West of the Bay Area
Resource for Cancer Control
in
Alameda, Calif., and Gregg Wilkinson
of the University of Texas School of
Medicme at Gah·estnn.

- B)· Anhur Page

ELDERLY
BLACKS
HAVE
GREATER
NEEDS
Bur
GETLESS
HEALTH
CARE
he elderly black residents of New
York State receive far fewer health
and social services than elderly
whites, even though the blacks' needs
are much greater, according to a landmark study by UB's Mult1disc1plinary
Center on Aging.
Conducted hy Arthur Cryns, Ph.D.,
professor of soCial work and senior
research professor with the center, and
Kevin M. Gorey, research assistant professor, the study was the first comprehensive attempt co examine the health and
social needs of blacks acr~ the state.
The researchers found:
Black elderly people arc 4.5 times
more "vulnerable" than elderly in the
general population, with vulnerahility
defined as having three or more unmet
health or social service needs.
Gorey said needs were simply the
"necessit1es of daily living, ranging from
transportation, housekeeping and food
preparation among the social services,
to the health care provided by a physician, hospital or nursmg home."
13.9 percent of elderly blacks are
health care "dependent," compared to 8
percent of the elderly in the general
population.
The proportion of elderly blacks
considered self-sufficient is less than
one-half that found among the elderly

�3

in the general population.
Elderly blacks have only half of
their social services needs met.
Economic reasons were listed as the
most potent factors explaining the variation in services among the elderly.
"Medicaid does essennally what it
was designed to do, but that means
nothing for the near-poor, those severely impoverished but unable to meet the
criteria for aid," Gorey explained.
"Forty-six percent of tho e surveyed
lived under the U.S. povert) line.
Unfortunately,
26 percent are very
close to the po\'erty line and can't meet
expenses from their pocket."
The study was funded by the New
York African-American
Institute, a
component of the State University of
New York established in 1986 to initiate, conduct and coordinate applied
and historical research on blacks, especially New York State resi&lt;lents.
Japhet M. Zwana, Ph.D., director of
research and special proiect for the
institute, termed the study ""ery important" and hoped it would be applied co
policy decisions addressing the disparity
in ser\'ices.
The study "demonstrates the magniwJe of the problem and confirms our
worst fears," said Arthur Eve, deputy
speaker of the New York State
Assembly, who added chat he planned
to hold public hearings on the issue.
"The existing institutions are making a concerted effort. bur the minority community must &lt;levclop our own
support network," Eve said. "We must
be empowered."
He acknowledged the need for more
black doctors within the black community, recommending more ,cholarsh1p
money to thb end.
"Above all, we need more resources
and stronger institutiom," E"e said. "It's
an unequal system."

The study was based on responses to a
lengthy questionnaire by 1,542 elderly
blacks, 1,057in New York City and 485
in the upstate cities of Buffalo, Rochester,
Syracuse, Albany and Binghamton.
In most cases, the upstate participants
were found to have greater unmet needs
than those in New York City, a trend
that may reflect the fact that more services are in place in the latter.
- By JeffreyTrebb

the body to excrete large amounts of
water and salt and could he useful in
treating people who have fluid retention disorders.
For instance, in pregnant women
with rnxemia, immersion has been
found to lower blood pressure
significantly and increase the excretion
of salt and water without drugs that
coul&lt;l harm the fetus.
'That's the nice thing about immersion- 1r's not a pharmacological treatment," Krasney pointed out.
As a person sits in a tub of water,
the water preswre squeezes the blood
from the legs up into the chest, until
the volume of blood in the heart and
lungs is coo high. How does the body
adjust? It eventually tries to reduce
the blood volume by getting rid of
fluid through urination.
"Water immersion produces a very
profound and sustained diuresis,"
Krasney said. "If we didn't have kidneys,
when we sat in water, our blood volume
m the body would ri,e enormously."
Da\'id Pendergast, Ed.D., professor of
physiology, has shown that the response
of the kidneys is reduced in athletes,
particularly in swimmers, though it's
not clear why.
The body excretes fluid not only from
the blood, bur from cells as well,
Krasney belte,·es. A subject immersed
for six hours excretes so much fluid,
he'd have very little plasma left if all of
the tluid came from the blood.
Another indication that water is
shifted from cells is the fact that people's skin gets wrinkled m water, he
said, though the wrinkling coul&lt;l be
caused hy the temperature of the water
or other reasons that aren't clear.
"Our major area of interest i, why
chi,; major fluid shift occurs and what
implications
H has for therapy,"
Krasney explained.

SOAKING
INA BATH
WARMSPHYSIOLOGIST
TOITSBENEFITS
ince ancient Rome, people have
touted the curative powers of a
long, relaxing soak in the tuh.
Now scientists are taking a second
look at the medicinal properties of the
bath in treating high blooJ pressure,
inflammation of the kidney, cirrhosis of
the liver, and toxemia during pregnancy.
Data resulting from this renewed
interest in "head-out water immersion,"
as scientists call 1t, was reviewed in
September at the first international
symposium on the topic. John Krasney,
profe.ssorof physiology at UB, delivered
the keynote lecture.
Scientists are interested in heaJ-out
water immersion, Krasney explained,
because soaking in a rub of water causes

�---

:(]}---.,. E ._ \.

4

There are probably ma1or shifo in
blood flow patterns from one part of the
body to another, he added.
Krasney's immersion scudtes are pare
of a program project from the National
Institutes of Health called "Environment and Oxygenation:
Delivery,
0iffw,ion, and Toxicity." The principal
investigator is Suk Ki Hong, M.D.,
Ph.D., professor of physiology.
The Physiology Department at UB
abo uses water immersion in ocher ways:
As a t0t)l for studying temperature
regulat ion.
As a way to study the effects of
increased blood volume without actua lly adding fluid to the blood.
§
To simulate the weightlessness
t
JosephC.Moll
endor
f, Ph.D
encountered by astronauts.
Water immersion is also used in I
physical therapy, Krasney noted, and
more work should he done to understand how it may affect blood flow to
injured muscles.
II
ealchy" wheelchairs chat do a
"The whole area is exploding clinilot more than provide a
cally," said Krasney. There are only
means of mobility are the goal
about 30 researchers in the world study- of UB researchers.
ing head-out water immersion now, but
Incorporating a patented system they
he expects that there will be many
developed that enabled a young paramore when a second symposium on the
plegic to ride a tricycle, che prototype
topic b held in Italy in 1991.
wheelchairs being developed by the
At the September
symposium,
researchers would exercise the muscles
Krasney received an honorary life mem- of users' legs as well as strengthen their
bership in the Doctor Richard Bright
heart and lungs.
Society, the group formed to perpetuate
Wheelchair
modifications
being
research in kidney disease that sponinvestigated by the UB team include
:;ored the symposium.
the addition of hand cranks and
Ironically, the symposium was held in replacement of conventional footrests
Bristol, England, co honor Bright, the
with pedals. The wheelchair~ would be
father of renal medicine. But Bright
moved by a combination of the user
didn't think very high ly of water
operating the hand cranks and his feet
immen,ion, noted Krasney.
pushing on the pedals as a result of electrical stimulation of muscles in his legs.
- By Connie OswaldStofko
"This is a new concept to incorrorate
exercise inw the normal daily activities
of the wheelchair-hound
person,"

!

I

explained Frank C. Mendel, Ph.D.,
associate professor of anatomical sciences and founder of the UB Spinal
Cord Injury Research Interest Group.
"It would allow the paralyzed or weakened lower limbs to be exercised on a
regular and habitual basis," he added.
"Every time users move che wheelchairs, they would exercise their lower
limbs. This would pump blood pooled
in their lower legs upstream so the re
would be less swelling of the legs. It
also would move their joints so there
would be less likelihood of decubitus
ulcers forming."
Turning the hand cranks and movement of the legs also would provide aerobic exercise strengthening the heart
and lungs.
Wh ile wheelchair users currently
may derive such benefits from costly
exercise devices, usually limited co hospitals or clinics, the system proposed by
the UB researcher~ would provide them
dunng routine activities in the home,
at work and elsewhere.
The work dates back to a discussion
between Mendel and his accountant,
father of a then 6-year-old girl who was
confined to a wheelchair after her legs
were paralyzed at age 3 .
With hopes that she someday will
walk again, her parents wanted co mamtain the integrity of the girl's leg muscles.
The UB researchers' solution also
provided a means to strengthen rhe
youngster's heart and lungs and, literally, a vehicle for joining her siblings and
friends for a spin around the block.
They replaced the Big Wheel's handlebars with hand cranks synchronized
with the tricycle's pedals using chains
and cams. The trike was propelled by a
combination of the youngster moving
the hand cranks and her feet, held in
stirrups, pushing on its pedals as a result

HEALTHY'
WHEELCHAIRS
REALLY
GETLEGS
MOVING

BLFF:\LO PHYSICIAi-.::\1'D lllL1\{Ei'IC\L !-CIE!-.Tlq

�---

:CE}
---J'E,.q.

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of electrical stimulation of two secs of
muscles in the thigh of each leg.
Electrical stimulation of the users'
leg muscles is a key factor in the
benefits derived from the modified
trike and the wheelchairs envisioned
by the UB researchers.
"If we don't stimulate them, che
lower limbs would simply go for a
ride," Mendel explained. "They would
get no exercise."
ln addition to Mendel, members of
che team are Dale R. Fish, Ph.D., U B
associate professor of physical therapy
and exercise science; William Tanski
Jr., director of the UB Health Sciences
Instrument
a nd Fabrication Shop;
Robert Kell, retired electrical engineer
formerly with Calspan Corp.; Joseph C.
Mollendorf, Ph.D., UB professor of
mechanical and aerospace engi neering
and Darold C. Wobschall, Ph.D., UB
associate professor of electrical and
computer engineering.
The work is funded by grants from the
New York Stare Science and Technology
Foundation, Gaymar indust ries Inc. and
Index Electronics Inc.
- ByArchur Page

Endothelium
can
respondto variousstimuli,
notonlyas the
productofinjury,as
we havealwaysthought,

but:alsoby undergoing
'activatwn
. . ,' says
RarnziS. Cotran, M .D.

endoithelium.
BLOOD
VESSELS'
LINING of Cocran
is the Frank Burr
DOESN
'TJUSTSITTHERE Professor of Pathology at the
he endothelium isn't just a coat for
the blood vessels, but is a very
active protagonist, according to
Ramzi S. Cocran, M.D., who delivered
the fall Harrington Lecture at UB.
Cocran is a recognized leader in the
study of endothelium, which is the lining of the cavities of the heart, the
blood vessels, lymph vessels, and other
organs. With Guido Majno, M.D., he
did pioneering studies on the structu re

lll:FFALl ) rHY~lCl:\N ASD 810 \IEDI CAL :;...
:tESTl~T

Mallory
Harvard
Medical School and chairman of the
Department of Pathology at Brigham
and Women's Hospital, Boston.
He and hi colleagues found that ''the
endothelium must be doing something
more than just sitting there as a passive
bystander as was previously thought,"
Cocran said.
Endothelium can respond to various
stimuli, not only as the product of
injury, as we ha\'e always thought, bur
also by 1Jndergoing "activation."

Endothelial acti\'ation means there
are quantitati\'e
changes in specific
gene products which endow the
endothelial cells with new o r altered
capacities co perform specific functions.
This is significant because the activated endothe lium can express new
molecules that weren't expressed before
on the surface. These newly expressed
molecu les can influence:
coagulation
adhesion of blood cells co the
organs, which can produce inflammation
new antigens, especially antigens
that can influence rejection in transplanted organs
This endothelial activation occurs in
the boJy as well as in cell cultures and
may lead to vascular inju ry, Cocran
said.
Endothelial cells can be activated by
cytokines, which are stimulating factors
(such as for growth) that are released by
cells in the immune system (such as
lymphocytes) or by endothelial cells.
Cocran focused on the cycokines interleukin- I, tumor necrosis factor (TNF),
and gamma interferon.
A member of the Institute
of
Medicine of the National Academy of
Sciences, Cocran also is a past president
of the American
As:.ociation
of
Pathologists
and on rhe board of
trustees of the American Board of
Pathology . He serves on the editorial
boards of several medical journals,
including the American Journal of

Pathology.
Dedicated co medical education as
well as being a researcher, he is coauthor of a very popular medical
pathology book, Pathologic Basis of
Disease,which is used at UB and other
medical bchools.
- By Connie OswaldScofko
FormoreResearch
• seepage23

�6

and
feeingnopain

BY ANTHONY Cl I A'-if.

,rn1~(, 1990

c.:upunc111rl•\ ad\'1K·,11e, m,1,1 1hat 11 ,me rt.·ali:6 that nw,t of thc:,e patiench,1, bencfitted b11l1on, ,m1.e It \\a,
~cek Oh\ hdp onl} a, a la t rc-.ort.
mtrl,duccd mnre th,1114,000 \e,1r, ago.
"The,e pafll'llt ha\·e often heen to
\Vhy, tlh·n, Jo "1 m,1ny A llll'ric.in
man) doctor,," c:xpla1m Oh. "They'n•
ph},ic1,m, remain shpt1c,1l of 11?
"~1a}bcthe} feel that other science,
h,1\"Cmm1.•de,n-cut prooh l&gt;I hm\ thq
work," ,uggc,ted Ju1\l' (Joung R,1) Oh,
~1.D. On the other hand, ,he ob-.:r. e,,
"Once ( pl ,1c1 1 ) h,1\ e rcicrred a
p.1t1ent, ,1nJ ,een g110J re,ult,, thq
h:coml' nh1re c.:onhdult."
Oh, as I tant professor of rl.'hab1l1ta•
t n • 1.•d11.
me at UB and ,mending
phy,1cnn m rehah1l11,111onml·d1cine ,1t
the Erie Count\' ~kd1c.1l C1.·ntl·r, h.1,
CIIJO}cd t,trtlmg re ulb u,mg thl' tedt•
nique 1111r1.',II
a d1\as1.· r,mcc ,111.hmnu.:
p,11n:bur,111, lo\\ l'r b.1d: ,tr,un, t ngem•
m,11neur,1lg1,1,m1gr,111w
he,1d,1dw, neck
and ,h11ulller [Min,
Bell\
p,il,),
had ph\,1cal thl·r&lt;1p\ and nothing h,1p•
o,tco.utlmt 1,, te111H dbm\ ,md e\ l.'n pened; med1c,1wm, and \Ct the problem
Mnu, hcacbchc.
,nil per,1,red. The\ come 111 de,1,craIn De1.l'lllher, EC MC opem·d .1 nl'\\' t 1011,\\ 111
mg to g1,·e anyth mg ,\ try."
,11.upun1.tur1.·
center, the onh ,ud1 cen•
P,111enr,m·I\ come co hl•r 111 de,pcr,1•
ter in ,1 \Vcstem Ne\\ York ho,pnal. Oh
tlOn, I t the u,uall\· lc,t\ C harr}, able
rt. •r1' h.11 5 percent of her patient,
to funcuon better, ffillre cncrgeuc, and
there l'XPl"rienn· g,111dr1.",t1lt-. The:
in ,ome tnsl,lll&lt;.:l''
ahl1.• to return to
t 1t1,tH. 1 e,peci,1lh impre~,l\'t.• \\ hc:n wnrk for the tir,1 tune m ,1gc:,.

llU!FAI0Pll\'1&lt;1AN
A~lll\l

\IIDI

c\L~lf~TIST

�7

/

JuneOh, M.D.
, left, an assistantprofessorof reh1abilitationmedicine
at UB
, is oneof the fewM.D.s in the Buffalo
areawho
usesacupuncture.
Aboveis oneherpatients
, a 6!;-year-oldwomanwithosteoarth
ritis.

P n 0

t OS

BUFFALO PHY~ICIAS A~O BlmlEDIC.-\L ~IE.'-:Tl~T

b

'Y

b 0 b

\\ a

0 n
:SPRISG1990

�8

Torelievekneeandanklepaincausedbyosteoarthritis,
needlesareinsertedintothewoman
's legs, above,andhands
, right.
"My specialty here (at ECMC) is
neuromuscular problems," says Oh.
"Multiple sclerosis, strokes. Pain resulting from car accidents, whiplash, amputatiom. Anything dealing with muscles
or neuroproblems.
"I see occupationally related pain X-ray technicians who do a lot of lifting, those who lift a lot of patients they have pain in the shoulder blade,
and yet the X-ray shows e, •erything to
be O.K. Nobody can find anything, but

'&lt;PRISGIWJ

acupuncture relieves the pain. I do see a
lot of that."
"Acupuncture is a respectable, safe
approach to chronic pain," said Glen E.
Gresham, professor and chairman of
rehabilitation medicine at UB and director of rehabilitation medicine at ECMC.
Acupuncture is Just one of many different therapies, ranging from drugs to
electrical stimulation, that are a\'ailable
to doctors to treat pain, and no ~ingle
therapy worb for everyone.

"Acupuncture
is an accepted and
respected alternative in this array of
approaches," Gresham said.
The technique, notes Oh, is almost
painless. A number of very fine needles
are inserted at designated points that
are mapped out on a chart in Oh' s
office. (In Chinese, the points have
names; in English, they have numbers.)
Most people find the acupuncture treatment very relaxing; some of them even
fall asleep.

�ECMC. She joined the staff of the hospital m 1972 as an assistant attending
physician.
le wasn't until Oh had lived in Buffalo
for several years that she decided to
study acupuncture. In a search for alternatives for patients who did not respond
to available treatment, she embarked on
a specialized 300-hour course in
acupuncture at UCLA in California.
That course allowed her to become
licensed last year to use the procedure
in New York Scace. The pink licensing
certificate is proudly displayed on her
office wall.
"Ir took three years to get that paper,"
she exclaimed.
Today, acupuncture
constitutes
between 30 and 40 percent of Oh's
practice.
Western physicians do not yet trust
acupuncture completely and imurance
doesn't co\'er the technique. Perhaps
it's not accepted because it's not clear
how it works.
"No one knows exactly
how
acupuncture blocks pain," Oh confirms,
but ventures a theory. "Pain appears to
involve multiple systems including
peripheral nerve endings, brain stem,
midbrain reticular formation, thalamus,
and prefronral cortex.
"When I insert needles and manipulate and twist with my fingers, there ts an
area that stimulates the pain pathway to

I

A native of Korea, Oh grew up in a
culture that accepted acupuncture.
When she was a child, her parents took
her to an acupuncturist for successful
treatment of stomach pains.
She studied medicine in Korea, graduating from the Ewha Women's
Medical School in Seoul. Then she
completed an internship at the Bronx
Lebanon Hospital in New York City
before coming to Buffalo to do a residency in rehabilitation medicine at

BUFF,-\Ll) r t-n~l(' I -\~

\!',;l)

RIOMEPICA I. :;(: l~ Tl'-T

Ele&lt;trocles
are
oftenattached
to theacupunctureneedles.In
thiscase, Dr.Oh
said,thepatient•
wasableto get
around
without
herwalker
,
walkfaster
, and
evengo shop·
pingaftera few
treatments.

the middle brain and the spinal cord.
The concentration of certain naturally
occurring hormones (such as endorphin)
is increased and the pain is controlled."
Successful acupuncture,
notes Oh,
depends on the integrity of nerve function. About half of all known acupuncture points are in some way directly
related to the peripheral nerve, and
more than 35 percent are located close
to the peripheral nerve.
This is not the first time an acupuncture clinic has been housed at ECMC.
An earlier clinic was started at the hospital in 1974, back when it was known
as the E.J. Meyer Memorial Hospital.
The clinic closed after a little more
than a year when the initial high
demand for acupuncture slacked off,
said Ross Markello, M.D., who headed
the anesthesiology departments at the
ho pital and UB.
There were also some doubts about
the effectiveness of the treatments,
noted Markello, who is now an emeritus professor at UB and an associate
medical director at Independent
Health, an HMO. A review by psychiatrist~ showed that 33 percent of the
patients felt they had some improvement - exactly what you'd expect
from a placebo.
Oh bristles slightly at the suggestion
that acupuncture might be a kind of
hypnosis or a placebo.

9

�10

I

Inanotherpatientsufferingmusclespasmsandpainafter backsurgery
, acupuncture
needleswereinserteddirectlyintotheback.
Thepatientreportedfeelingwarmandrelaxedafter thetreatmentandthe spasmsstopped.

�"It's not a placebo effect at all," she
states matter-of-factly. "You can see in
China where surgery is performed on
alert patients using acupunctu re that's no placebo.
"In Western New York it's not as
common as it is on the West Coast,"
adds Oh. "In California, a great deal of
acupuncture is practiced, not only by
Chinese acupunctu rists, but by physicians as well. Western New York is more
conservative, anJ nor as accepting of
acupuncture as a medical treatment.
"Since I started here at ECMC, and
the patients who have come here have
had good results, word of mouth has
been good. In fact, a neurosurgeon at
ECMC has begun to send patients who
still have back pain after surgery to me."
Doctors' relatives and doctors themselves also go to Oh for treatment. She
was able co relieve the "tennis elbow"
pain from which one doctor's wife had
suffered for more than a year. A physician sought her help for Bell's Palsy, a
disorder that leaves one side of the face
weakened - the face becomes asymmetrical as one side droops. After six

treatments his face is balanced again.
Although behavior moJificacion is
not really in her lme, Oh has even been
able to assist the efforts of hospital
employees to quit smoking.
"Somehow, acupuncture b very effective to help people quit smoking," says
Oh. "People have been able to quit
smoking after 30 years!"
When acupuncture
needles are
manipulated in the patient's ear, body
chemistry is altered and the desire to
smoke is diminished. she said.
"Once people start smoking again,
they're back in the habit," warned Oh,
"but the technique works beautifully. I
did it for cwo patients who are employees of the hospital.
"I did it reluctantly, because l am not
exclusively an acupuncturist.
I am a
physician who uses acupuncture as a
tool in her practice. My practice at
ECMC is a medical practice. Thirty or
40 percent of my practice is acupuncture, as indicated when these patients
need pain control."
Those who are exclusively acupuncturists and do not hold an M.D. or

D.D.S. travel a different route ro ger
licensed in New York Scace, according
to T homas J. Monahan, executive secretary of the State Medical Board.
They muse already have an acceptab le acupuncture license from another
state or country, along with appropriate
training in acupuncture and 10 years of
experience outside New York Stace.
Because of the way the statute is written, most acupuncturists
licensed by
New York were trained m Easr Asia ,
Monahan noted.
Licensed acupuncturists outnumber
physicians who use the technique in
Western New York - Oh has heard of
only one besides herself. But perhaps
one Jay it won't be so rare.
"Acupuncture is not yet completely
accepted in the medical profession, bur
pretty soon it will be," she predicts.

Anthony Chase is the coordinawrof Academic
Services for the Educauonal Opponumt)'
Programat BuffaloState Collegeand a prolific
free-lancewriter

HowMANYDIFFERENT
WAYS(AN You
SPELL
RELIEF?
cupunctu re 1s 1us t one
alternat1\'e
for treating
pain.
While no single method can
claun to be JOOpercent effect1\'e,
"a ll of these th ings work \'ery
well for some people," noted
Glen E. Gresham, professor and
c h airman
of rehabil1tation
medicine at UB and director of
rehahd1tat1on
med1c111e at
ECMC.
Dru g th e rap y co m b in ed
with ph ys ical th era py. This 1s
the most common
methoJ,
according to June (Joung Ra)
Oh, M.D., assistant professor of
rehabdnation
medicine at UB
anJ attending physician m rehabilitation med1c111e at the Erie
Count) Medical Center.

TEN S - tran sc utan eo us
el ec tri c al n e rve s timulati o n.
An electrode 1s pasted on the
skm which deliver, a low-\'oltage current.
"A Im of people gee relief from
this method," noted Gresham. "l
think there's a physiologically
similar mechamsm to acupuncture."
Tri gge r-po int inj ec ti o ns .
"This 1s \'ery fashionable for people who ache all over," noted
Gre:;ham.
If a physician can find a pomt
on the skin that cause:. this allO\'er achines, when pressed, he
can inject the point with a local
anesthetic or corticoscero1d, or
both. The trigger pomts mav
coincide with acupuncture point~.

Freez ing. Freezing the area
\\ ith a \'apocoolant spray bricth
frec:cs and numbs the spot. The
muscle can be stretched
to
relca:ie ,1spasm.

.,

11

�Timmy
Mathias'mother,Kerry,talksto herson
as he recuperates.

�13

BY EDWARD

J.SYLVESTER

Noonehadeverrecovered
fromsuchan
iniury.
Theboy'sheadwasattachedto his
bodybyonlyhisspinalcord,a fewmuscles,
andskin,andhisbrainstemwasdamaged.
Butthanksto theworkofa UBalumnus
andotherneurosurgeons
inPhoenix,
the
boyeventually
walkedoutof
thehospital,
smiling
and
talkingto reporters.

...

Timmy
Mathias
'mangled
bicycle

�Spnng had arnved in Phoenix, Ari:ona,
and the weather on April 26, 1989, was
sunny and inviting. But neurosurgery
resident Brian Fitzpat rick didn't have
14 time to notice.
It was 8 a.m. and he was already in
the middle of his bu,y morning rounds
at St. Joseph's Hospital when he was
,ummoned to the emergency room: A
young boy on a bike has been hit hy a
pickup truck and had JUH been airevaced from the accident sm: m suburban Phoenix.
In the emergency room, the trauma
ream, paramedics, and nursing staff
worked on the unconsc10us 10-yearold hoy who was strapped to a hack
board and protected by a cervical co llar. X-rays indicated that the boy had
suffered ltfe-rhreatening
internal
injuries and needed to be rushed into
general surgery.
Fit:patnck, a 1986 graduate of the
UB med ical school on a pediatric neurosurgery
rotation
with Barrow
Neurological lnstttute m Phoenix, was
called co check for spine and neck
injuries, and he began the first medical
workup of the case that would dub his
patient "the miracle child."
At first, doctors had only hmt:, to the
extent of the injuries suffered l,y
Timothy I. Mathias Jr. From the X-rays
111
the emergency
room,
taken
Fit:patrick and spine specialist Steven
Papadopoulos, M.O., saw evidence of a
!X)tentially lethal separation of the boy's
neck vercehra from his skull.
Timmy was sent for CT scam, which
offer a much finer resolution than ordinary X-rays. From chose, the doctors
suspected somethtng even worse: a
fa111tshadow suggested blood on the
hmm stem.
A, Fit:patr1ck accompanied
the
unconscious hoy's gurney, rushing from
the emergency mom to the CT scan to
general surgery, the hoy's condition
worsened. He didn't blink when hts
eyes were toucheJ anJ his pupils didn't
contract m respome to light, a sign of
hram stem miury.
In genera l surgery, physicians were
able to sa\'C moM of the hoy's ruptured
spleen, mended his li\'er and kidney,
and stopped hi, internal bleeding.

was rushingX-rays and CT scans
among the specialistsof Barrow's neurosurgery
team, but he was deliveringincreasingl
y bad news.
"It becameapparentthat Timmy's headhadbeen
separatedfrom his spine," Fitzpatrickrecalls, "and
that the brainstem hadbeen damaged as well." A
review of the medicalliterature confirmed what
everyone now suspected: No one ever recovered
from such an injury.
Meanwhile, Fit:patrick was rushing
X-rays and CT scans among the specialists of Barrow\ neurosurgery team, but
he wa.....deli\'ering increasingly bad news.
"It liecame apparent that his heaJ
had been separated from his spine,"
Fitzpatrick recalls, "and that the brain
stem had heen damaged as well."
A review of the medical ltterature
confirmed what everyone now suspected: Of thme accident victims whose
skulls had broken loo,e from their
spines, a tmy proport ion suffered no
bram stem injury; if immobi lized quickly, the, recovered. But of those who
suffered any bram trauma what oever,
none reco\'ered, no marter how quickly
they were immob1li:ed. All either died
or remained vegetative.
Timmy haJ pulled through general
surgery, but Fitzpatrick and his colleagues still faced a challenge. They
needed to know precisely where the
suspected brain stem inJUI)' was located.
There 1s no such thing as exploratory
brain surgery, Fit:patnck pointed out
later in an interview; the neurosurgeun
mu,r know exactly where he is headed
tiefore he starts surgery.
Only a magnetic resonance image
(MRI) would disclme the 1nJury plainly enough for surgery, but the powerful
magnet required to take such a scan

would disrupt the respi rator, killing
the boy.
"Our fin,t break was in having a new,
experimental MRI scanner," Fit:patrick
explained. "This was a low-field scanner,
Jes1gned not to interfere with a respirator. The question was, would it work?"
It d,d, enabling Fitzpatrick
and
Papadopoulos to rush a set of cryscalclear scam to the viewing screen.
But as each MRI scan was placed m
the light in the early afternoon, recalls
Harold Rekate, M.O., the pediatric
neurosurgeon under whom Fitzpatrick
Web working, "the news got worse. We
were shocked," he says, a word not frequently heard among neurosurgeons.
The separation of Timmy's neck from
his skull was more severe than any of
them had ever seen, and a walnut-si:ed
blood clot pressed against the front of
the boy's brain stem.
By m1d-afcernoon, a growmg ream
huddled around the MRI scam on the
lighted wall panels. There was Robert
Spet:ler, Barrow's chief, who is known for
his aggressive and successful treatment of
aneurysms and stroke; Volker Sonntag,
the spine surgeon who had in\'ented an
implantab le pin that would be used to
reconnect the boy's spine to his skull;
Rekate, chief of pediatric neurosurgery;
Fmparrick, and Papadopoulos.

�IS

Thethinblackarrowsshowhowthe skullwas separatedfromthe spine.Thefat whitearrowindicatesthe bloodclotpushingonthe spinalcord.

RL'FFALOrHYsJCI-\'\ A'\ll

f\l0\1ElllC-\l

~-IE'\Tl'-T

�16

"Granted, there is little chance we
can save him," Spetder told the group.
"Bue 1f we do nothing, he will surely
die. If we do these things, we're going
to lose mo,c of the t11ne.Bur if we don't
do chem, we'll lose all the time.
"What are we waittng for?"
To Fitzpatrick,
,uch a moment
marked one of the intangihle values of
his residency.
"le is reall, that accicude at Barrow
that's important," Fir:patnck sar. "And
that's Sperzlcr's attitude. He b very
aggressive. If there's a chance of saving
someone, you take it.
"There were three things chat made
the surgery possible. First, the aggressive workup as soon as the boy was
admmed, mcluding the lo,\,-field MRI
scan. There was the assumption that
the worst might be true, hut we still
might save him.
"Second, the aggressive approach
Barrow rakes in brain inJttry ,·icttms,
especially children."
And the third ingredient chat was
needed co make the surger,· succcl-sful,of
course, was expertise. "Especially
Sonnrag's and Spetzler's," Fitzpatrick said.
Timmy's head had been immobilized
in a cervical collar and a backboard at
the accident scene, and 1n the late
afternoon Fttzpatrick and Papadopoulos
labored to fit him into a halo brace.
The halo hrace resembles a medieval
torture instrument, with a steel halo
chat encircles the head, held by pins
screwed into the bone. Four rods ristng
from a tight leather vest run through
loops 111the halo.
Fitzpatrick and Papadopoulos had co
make sure they didn't Jar Timmy's head
or spine, or they would destro~ the
unprotected delicate fihers of the brain
stem. Nothmg held Timmy's head on
but his spmal cord, a few mw,cles, and
skin. And the sp111alcord, to a neural
expert, is simply spidery filaments of
hra in ttssue.
Fit:patrick noted that the location of
Timmy's clot was a further complication. Ar the from of the brain stem, tt
lay directly hehmd the mouth cavity,
and the normal approach for surgery
would have heen through the mouth.
Bur raking that route would rhk
infecttng the brain w1ch mouth hacteria,

Above,Brian
Fitzpatrick,
a 1986graduate
of which would certainly be fatal.
Spet:ler had developed a technique
theUBmedical
school,
checked
Timmy's
progress
dailyandsawradical
improvement. for reaching previously inoperable
aneurysms through an approach from
Within
theconfines
of hishalobraceanda
the back of the neck. That meant
legcast, nmmywasableto laughandplay
likeany10-year-oldandeventually
walked Fit:patrick and the ochers had co roll
the boy onto his stomach hefore
outof thehospital.

surgery, another reason why the halo
brace was critical.
It was nearly 5 p.m. as Fitzpatrick and
Papadopoulos wheeled Timmy into
Operating Room 2 and scrubbed in.
Across the hall, Spetzler was completing eight hours of delicate surgery,
clamping off a blee&lt;lmg aneurysm deep
within a 64-year-old man's brain during
a procedure known as a "scambtill" - a
complete cardiac arrest in which the
bram is drained of blood and chilled to
hring metabolic activity below the normal threshold of life. Spetzler scrubbed
out, crossed the hall, scrubbed in and
hegan again.
The doctors cue down to the spme,
parred rhe neck muscles, and worked
around to the front of the bram stem.
Fmally, the clot could be seen. The
only hopeful sign they found was that
there had heen no new bleedmg.
The clot was drained and the doctors
began the arduous task of reattaching
Timmy's skull and spine with Sonnrag's
V-shaped pin. The open ends of the
"V" were wired to the vertebrae and the

�the surgery, Timmy was essentially
Fitzpatrick's patient. "He began to show signs
that his paralysiswas improving almost
immediately," Fitzpatricksaid. "But the really
1

l

big moment came severalweeks later when we
asked him to show us two fingers, and suddenly
two fingerspopped up. That was the first time we
knew he was awake. "
"V" point was fastened to the skull with
wires looped through tiny holes drilled
through the bone. The surgery took
about five hours.
It was well after midnight, 16 hours
after Timmy was brought in, by the time
Rekate and Fitzpatrick met with Timmy's
parents. They had been told there was
only a 1-in-20 chance chat Timmy would
survive. Now it appeared he had beaten
those odds. Bue how far he would come
back was completely unknown.
Timmy
was now essentially
Fitzpatrick's patient, on Rekate's pediatric neurosurgery service.
"He began to show signs that his
paralysis was improving almost immediately," F1t:patrick says. The morning
after the operation, Timmy began moving, though he was too dee p in a coma
to follow commands.
Timmy's movement was amaz ing
enough. "Bue the really big moment
came several weeks later when we asked
him to show us two fingers, and suddenly two fingers popped up. That was che
first time we knew he was awake."
Fitzpatrick visited Timmy twice a day
on rounds and saw radical improvements day by day.
In mid-May, a press conference was
scheduled to discuss Timmy's condition.
The story of Timmy':, rema rkable
surgery had already been told in newspapers and magazines and on television
around che world. Speeder had even

been inte rviewed by Tass, the Soviet
news agency. Tim my was pictu re d ,
while sti ll comatose and in halo brace,
on the cover of Stern, Germany's major
news magazine.
Tho ugh cheered by Timmy's progress,
Fitzpatrick still was as surprised as the
rest of the medical staff when Spetzler
confidently said at the news conference,
"Timmy will walk out of here."
Within a month after the accident,
Timmy was acting like any I 0-year-old,
chatting and laughing. He moved as
much as he could while wearing the
restrictive halo brace and a leg case,
which had been applied a few days after
the accident to mend his broken leg.
Because several vertebrae are fused
with the V-shaped pin, Timmy will
always move his head as if he has a stiff
neck, but there doesn't appear to be any
permanent brain damage.
Speczler's prediction was correct, and
Timmy finally walked out of the hospital on June 23.
Reflecting on that surprising forecast, Fit:patric k finds a lesson for neurosurgeons.
"Timmy had a le:,ion we could see, that
we removed. That tell you that a more
aggressive workup may show a hopeless
problem to be treatable, in some cases
even curable," Fitzpatrick said.
Neurosurgery
has appealed
to
Fitzpatrick since his first year of medical
school at UB when he conducted

research at Millard Fillmore Hospital
with Nick Hopkins, M.D., now chairman of the Depa r tment of Neurosurgery at UB, and James Budny, M.D.,
vice chairman of the department.
"Working with them was very exciting," he said. "It showed me the direction to take."
His decision to become a doctor goes
back even farther; way back to Amherst
Central Junior H igh.
His biology class had shown him for
the first time "new insights instead of
just a continuity, a new way of looking
at the world," he said.
The son of Robert C. Fitzpatrick,
director of research developme nt in the
UB School of Dental Medicine,
Fit:patrick the n majored in neurobiology at Cornell. After graduation, he did
his required year of general residency at
Millard Fillmore.
Fitzpatrick chose to continue his neurosu rg ica I training
at Barrow
Neurological Institu t e in Phoenix,
A riz., because he wanted a bu y neurosurgica l service. And, he had heard,
unlike Barrow, many better-known
institutions don't allow residents to perform surgery until their final year.
Another drawing card was Robert
Spet: ler, Barrow's chief, o n e of t he
world's leaders in vascu lar neurosurgery, the area in which Fitzpatrick
was most interested.
"The staff was young and aggressive,
and they were up on the latest technology," Fitzpatrick says. "And technology
proved important" in Timmy's case.
Soon after Timmy was re leased,
Fitzpatrick finished his pediatrics rotation in neurosurgery at St. Joseph's
Hospital in Phoen ix and began a sixmonth rotation
at trauma-hea\'y
Maricopa County Hospital in Arizona.
He is now chief neurosurg ical resident at University Hospital in Tucson.
Then it will be back to Phoenix and
Barrow again, and three more years to
complete one of medicine's lengthiest
apprenticeships.
EdwardJ. Sylt•ester,a memberof the Naaonal
Associationof ScienceWriters,is the authorof
The Gene Age: Genetic Engineermg and
theNext lnduscnal Revolution, «:ith Dr. Lynn
C. Kloc;:,and Target: Cancer.

17

�18

STETHOSCOPES TO
MICROSCOPES TO MICROCHIPS
Computers emerge as medicalschool's newest teaching tool

BY DAVID
HIMMELGREEN
he three-pound preemie
is suffering from respiratory distress syndrome.
Her breathing is lahored
and her skin casts a
bluish tint. She's hooked
up to a res-ptrator,but the
monitor shows that her
viral signs are not gO(.xl.
This is the medical student's first experience
with life-or-Jeach decisions in the intensive
care nur ery. Hands sweating and heart racing, the stress 1s almosl unbearable. The student must choose the right course of action.
Fortunately, even a bad decision has no
fatal comequences. This babv is made not of
tlesh and blood, but bits and bytes and pixels
- she exists imide a comrucer program.
The student types in an instruction to pass
a rube down the computer bahy's air passage.
The computer responds, mdicaung that oxygen 1s l:,eing delivered to the lungs, and che
baby's respiration is returning to normal. The
student also breaches easier.
Other complication., anse for the preemie, and
tomorrow's physician contmues to make decisions,
typing in further imrruct1ons. This "dialogue"
between student and computer contmut:s for p.:rhaps an hour, simulating four days in the baby's life.
Both a confidence builder and valuable experience for the future, this program 1s just one example of the cools now available co UB medical student!\ in the wake of the computer revolution of
the lace '70s and early '80s.
Today, even computer novices can use powerful
software programs to assist them in medical education, research and administration. said John
Loonsk, M.D., director of academic computing for
the medical school.

ILLUSTRATIONS

compu·
tersimulat
ion
allowsstudents
to honetheir
diagnostic
skills
andevenmake
mistakes
without
endangering
a
human
life.

BY

Computers can simulate patients and have the
potential tl&gt; cut down on the number of animals
used in teaching. They can look at X-rays or slide~
111 new \\ ays and access large amount~ of information, almost instantaneously. And computers
are becoming sophisticated enough to help
come up with soluc1ons to problem:..
Personal computers (PCs), which are
more accessible and user-friendly than
mainframe computers, are popping up
everywhere in hosritals and cl1111cal
practices. AnJ the software programs
are relanvely easy to use and more
powerful lhan ever.
Physicians of the 21st century
will be faced with a field of
medicme thac 1s more and more
complex and speciali:ed. Computers
will help them wade through the
mass of information and paperwork that they'll
encounter,
Loonsk predicts.
"Future rhysicians are going to
need to be computer capable," he said.
The UB medical school has been
usmg computer, to assist in pre-clinical
coursei., ,uch as physiology and biophysics,
since the 1970,. During those early days, computers were loaded on rumbling cam anJ wheeled
down the hallowed halls to labs and lecture rooms.
Today, the medical school has a computer lah,
now 111 ib third year of operation, located in the
Cary-Farber-Sherman
Addition on the South
(~fain Street) Campus. Loonsk, who graduated
from the UB medical school 111 1986, b director of
the lab and the newly appointed chairman of the
medical school computer mstruccion committee.
The computer lab 1s a multtpurpose facility that
uses and de\'elops computer programs. It offers

LI

SA

HANEY

I\CHA LO f'HY•ICI ·I' .-1'.'\11BI0 \1f.()ICAL :,c 1E:-.'ll q

�computer-aided instruction tn many subjects,
teaches "computer literacy," and teaches how to
use computers in medicine.
"Our students arrive with very wide and varied
backgrounds in computers," stressed Loonsk.
The objecttve is to bring student:, up to speed
on the computers and then introduce them to the
power of computers in educat ion, research, and
adminbtration.
One of the biggest benefits of computers is the
way they can manipulate the pictures thal medicine
already uses, such ai, rhotos, slides or X-rays.
Using a 51bill, Loonsk demonstrated a machine
called a digiti:er, which scam. rictures and convens them into informanon that the computer
understands. After scanning the bill, the computer
presented a super-high quality image of George
Washington's face on rhe monitor.
The digitizer enhances the image and can :oom
in on minute details that may not be seen b, the
rhysician at first glance.
Currently, Loomk and lrn, colleagues are busy
digitizing images that will eventually be used by
facully to teach students about things such as the
identification oi kidney stones anJ what different
tyres of bacterial infections look like.
Studenls and faculty ah.o have acces:, to four

,·iden-disk players that interface with computers.
Recently, the Medica l Students' Parent:, Council,
a group of parents of medical students that conheUnitributes time anJ money to a wide variety of medversityplansto
ical
school activitie~,
donated
an lBM
eventuaUy
tinkthe
lnfowindows
worbtation
with
video-disk
rlayer,
computers
computer
and
touchscreen
monitor
to
the
comthroughout
the
medical
schooland puter lab.
Medical students use the lnfowindows touchbeammultimedia
screen system in their introduction to clinical
imagesrightinto
meJicine course to study different types of heart
classrooms
and
laboratories.
Gone sounds and the cardiovascular system, said Loonsk.
A video of real patients being examined 1splayed
arethedaysof
heftingequipment through the video-disk rlayer. Students can also
request images of the heart anatomy simply by
oncartsand
couching the menu that's disrlayed on the monitor.
wheeling
it down
When the students touch the heart on the
thehalls.
screen in different spots, the computer plays the
different heart sounds that emanate from those
areas. Students can abo request graphs of heart
sound cycles, Loonsk said.
Students also have access to seven CD-ROM
players, which are similar to CD-music players
found at home. Instead of reading disks that have
captured the sounds of Verdi or the Beatles, they
read disks that contain computer data.
Like the video-disk plaver, CD-ROM players
use lasers to read information. But CD-ROM
players tend tO be more text-based and rely less on
images, though that may change in the future.
One use of the CD player is to provide a textbook on a disk, Loonsk said. Scientific American
now offers its consult textbook of medicine on
compact disc. This CD is regularly updated so that
students can get the most recent medical informa-

omputerscanenhance
an
image
, whether
it's theportrait
of
George
Washingtonona dollarbill
oranX-rayof a
tibia
. Dodorscan
thenmanipulate
theseclear
images
, zooming
inandetailsthey
mightotherw
ise
havemissed.

19

�tudents
canfistentocfdfer·
entheartsounds
bytouching
the
various
areasof
theheartshown
onthecomputer
screen.Thisis one
useof an
lnfowindows
workstation,
whichwas
donated
bythe
Medical
Students
'
Parents
Council.

20

tion with high-rel&gt;Olution images almost instantaneously on the computer.
There are also a number of medical Journals publishing on CDs so that access to current rel;earch is
becoming easier than ever, Loonsk explained.
The computer lab offers a numher of databases,
including the Physician's Desk Reference (PDR).
Loonsk pointed out that it is important to expose
students to the PDR program because It provides
them wtth a wealth of information on brand name
and generic medications and drug interactions.
Medical students are given a worksheet with
items about a patient's medical history, such a~
age, sex, symptoms and lab results. After reading
the information, the students must consult the
PDR to determine drug interactions and decide
which medications are best suited to the patient.
Students then write down their diagnosis and
therapeutic regimen on the worksheet for evaluation by faculty.
Loonsk envisions a time when patient medical
histories are integrated w1ch many different programs like the PDR.Information from many different oources could then be brought up on the screen
at the same time, without having to make cumbersome conversions herween different programs.
In the future, the miniaturization of computer
hardware may provide the physician with almost
.instantaneous access to medical information.
"Hypothetically, there are devices chat flip over
one eye and allow you to view data as it's projected directly on your retina," Loonsk mentioned.
Perhaps one day a physician will be able to use
this device to view a patient's medical hi. cory, lab
tests, and refer to the PDR in one fell swoop while
the patient is on the exammmg table.

tudents
cangaineasy
accessto huge
amounts
of
information
using
databases
suchas
thecomputer
versionof the

Physician
's Desk
Reference.

There is also a program that reaches UB students how to call up patient lab data from the
computer system of the Erie County Medical
Center. Soon students may get the opportunity to
work on various local hospital computer systems
before they begin their clinical rotations, Loonsk
added, making the student's transition co real-life
medical situations easier.
Another clinical database program available co
students and faculty 1s MEDLOG, which allows a
physician to examine specific charactemcics of his
patient pool.
For instance, if a physician wants to test a new
blood pressure drug on patients with specific characteristics, he can use MEDLOG co find the
names of the most suitable patients for chis drug.
After the test 1s done, the program can also be
used to analyze whether the drug was able to
effectively lower blood pressure for the sample of
patients, Loonsk said.
Another tool used in academic computing and
within l&gt;Omemedical schoob is known as "multimedia." Multimedia integrates images, animation,
sound, and text on a screen using multiple windows.
At UB, multimedia projects will llSecommercially available sofcv:areprograms and reshape them for
an individuali:ed solution to a specific problem.
One problem is visualizing anatomic relationships. The meandering route of the cranial nerves,
for instance, is as confusing as a New York City

�ersonol
computers
con
helpdoctors
send
a letterorcon
suggesta possible
diagnosis
ina
porticulor
case.

road map. Traditional textbook descriptions, illustrations, and the dissection of cadavers all help,
but still some students struggle.
Now, imagine a multimedia program where a
student can view a high-quality three-dimensional rotating image of the cranial nerves, along with
a text description, while conducting a dissection
with classmates.
While chat's in UB's more-distant future, a simpler version of multimedia is expected to be in use
at UB by the fall.

A

eady Loonsk and his colleagues are
using the digitizer to create images.
For example, images of cirrhotic livers incorporated with text descriptions will be useJto teach students about liver disease.
These images and text can easily be manipulated so that students can scan variations in the disease process and compare images to different types
of liver disease, all on the screen at the same time.
Another plan for the UB medical computer lab
is the eventual linkage with computers throughout the medical school complex. Faculty will be
able co utilize the lab's resources from classrooms
and laboratories in the building.
Addmonally, a video distribution network will
beam multimedia images and descriptions of
things such as disease pathologies and anatomical
structures to students while they are in lectures or
&lt;lomg laboratory work.
Using even simple PCs, the sky's the limit to
what students and faculty can do in the medical
school computer lab. The lab maintains more
than 35 IBM-compatible and Apple computers

ypotheticolly
, there
couldbedevices
thatflipoverone
eye andallowa
personto view
dataas it's
projected
directly
ontheretina
.

and a wide variety of software applications.
One program teaches about human heart
sounds. Students can choo e to listen to specific
preprogrammed heart murmur with the "patient"
lying down, sitting up, and breathing in or out.
A drawing of a patient's chest appears on the
monitor. The computer simulates the sounds a
physician would normally hear if he or she were
to place a stethoscope on different anatomical
points outside the chest.
Another helpful tool for students 1sa problemoriented program called Quick Medical Reference
(QMR) that'~ run on an IBM-compatible personal
computer. Like the systems in banking that decide
whether or not a customer is a suitable loan risk,
QMR makes decisions about medical diagnoses
based on specific clinical findings.
"lt (QMR) allows you to look at medical information in a totally different way than if you were
to read a textbook or other resource," Loonsk said.
"We can put up a disease and then sort the clinical findings in many different ways.
"For instance, we can determine the most frequently cited symptom in a large group of patients
or the finding that would most strongly indicate
that srecific disease."
For example, a -rudent can plug in the clinical
findings for a pregnant woman who is over 30 years
old, obese, and experiencing high blood sugar,
excessi\'e urination, and acidosis. Then the student
requests the QMR program to make a diagnosis.
QMR will interpret these findings and suggest gestational diabetes mellitus (diabetes in pregnancy)

21

�a potential Jiagnos1s, a,, well as lbt other d1sea:,e:,
from which the patient might be suffering.
The computer lab also offers tools for medical
anJ health related research.
One project, still in its embryonic stages, is the
Scoliosis Tempora l Imaging Project, which bassociateJ with the work of Robert Gillesp ie, M.D.,
professor anJ chairman of the Department of
Orthopaedics.
The goal in this pro1ect is co demonsuate,
through three-dimensional images, the progression
of scoliosb (a curYature of the spine) through time.
Even ordinary software used in business offices
can be helpful to physicians, though many aren't
yet familiar with what's available.
"We have word processing, Jesktop publishing,
databases, spreaJsheets, and graphics programs,"
Loonsk said, a,, well as electronic mail.
Combined, these programs can help a physician
set up long-term appointment schedules, present
well-written and concise consults, monitor illness
trends within a patient pool, and keep track of
billing and payments.
In the long term, Looru.k hopes that computers
will assist in the nuts and bolts of medicine by
quickly retrieving the most pertinent information
the physician needs to help a patient.
A big complaint in rneJicine today is that
physic ians are so specialized and medicine is so
technological char there is little time for physicians to per,onally interact with their patients.
Loonsk hopes that in the future compurers
will free more time for physicians to spend with
their patients.

a,,

22

WHATS ON THE l\1ENU 7

I

f you can't cell the hardware from the software
without a scorecard, take a look at this lbt of
items being served up at the UB medical school'~
computer lab.
Di git izer. This machine scans photos, slides
or X-rays and converts them into information
that the computer under~ranJs. Then a superhigh quality image appears on the monitor. The
d1git1:er can manipulate the image in many
ways, :,uch a~ enlarging a portion of rhe image
for cloi.er inspection.
Tou ch screen monito r. This 1s similar to the
monitors found in grocery scores that shoppers
can press to finJ in which aisle the anchm y p1::as are located.
Vid eo -di s k playe r. V 1Jeo-d1sk players use
lasers co read informauon from a disk anJ send
moving image, to a television-like monitor and

hecomputerlaboffers
toolsformedico!
researchers
and
clinicians
alike.
Byhelping
physi·
ciansquickly
retrieveinformation, computers
mayenablethem
to spendmore
timewiththeir
patients
.

send sound to a speaker. They can also score thousand, of ,nil 35 mm slides.
They allow users to see moving images of real
people, or a computer-generated image, and move
easily between the two.
CD -ROM playe r. Compact disk read-only
memory players are similar to CD-music players
found at home, but imteaJ of reading disks that
have captured the sounJ~ of VerJi or the Beatles,
they read Jisks that contain computer data.
Like the video-disk player, CD-ROM players
use laser, to read information. But CD-ROM
players today tend to be more text based and rely
less on images.
Multimedia. Multimedia integrates images,
animation, sound, anJ text, and can use multiple
windows.
Dat·1d Hnnmelgreen, tl'ho i, comple1inghis Ph.D. m
anthropoloff'.\'
at UB, has done researchon numuon and
food habits in Lesothoand Kashmirand plam w remm to
Africaw completehisdisseriacion
m chefall.

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:(]}---.; E J. ~

23

TEMPORARY
SHELTER
f OR
HOMELESS
ATUB
TESTED
portable shelter Jesigned ro prov1Je temporary protection from
the elements for homeless persons
passed its first fielJ test with flying colors in January, according to physiologists at UB.
The device could be used by hnmele:.s person., who refuse to go to a formal
shelter or cannot find room m one on
cold winter nights.
"We certainly con · ider something
like this as a la;,t resort," said Tom
Harmon, who came up with the idea.
Harmon was a street person for three
years and is now executive director of
the Friends of the Night People shelter
for the homeb,.
Researchers ,aid that whether it can
provide adequate shelter when the tempera tu re drops to near zero Jegrees
Fahrenheit and pre\·ent hypothermia
- a precipitous drop in core body temperature - remains to be determined
in additional testmg.
Suk Ki Hong, M.0., Ph.D., professor
of physiology at UB, anJ four colleagues
monitored Harmon, who \'olunteered
for the tesl, for sign, of hypl)thermia.
Not only Jid Harmon's core body
temperature remain normal. but the
temperature wiLhin the two-piece corrugated "pup tent" never dropped below
50 degrees Fahrenheit. The low temperature during the all-night test was 30
degrees Fahrenheit.
The idea for the temporary shelter
originated with Harmon. He proposeJ a
corrugated shelter based on his own
experience: One of the hest night's
sleep he had while homeless, he
recalled, was in a discarded corrugated
cardboard box that had been used for
shipping a hot-water tank. The corru-

gated material is insulating and holds in
the warm air.
The "Harmon Hotel" being tested by
UB physiologists resulted from discussions between Harmon and Peter
Pellegrino, sales manager for Great
Lakes Container Corp. of Lockport,
N.Y., a \'Olunteer at Friends of the Night
People, during the bmer cold snap that
hit most of the nation in December.
The prototype is a two-piece tube
that folds flat anJ is easily carried.
When a confining band is cut, the tube
"almost self-erects," resembling a triangular pup tent. The two telescoping
poruons of the tube adjust to the height
of the user. Although the user is completely enclosed in the tube, he or she
can get out of the tube easily.

TomHonmon
stayedwormthrough
one
of Buff
ollo' s winternightsinsidethe
"Hormo1~
Hotel.
"
Although the tubes are biodegradable
and Harmon envisions using them only
once or twice, they can be reused and
can be carried after the metal band 1scut.
Harmon said he e1wi:iions carrying a
suprly of the corrugated pup tents in

the trunk of his car and handing them
out to homeless people who need chem.
He also would like to make chem available to police, fire and ambulance personnel, as well as ocher shelters and
soup kitchens.
Great Lakes Container designed and
developed the prototype at no charge,
Pellegrino said. A charge will be
assessed if the company eventually
manufactures it, he said, adding chat
Friends of the Night People will receive
part of any profits obtained if the device
is sold co any group other than the
Buffalo shelter.
Assisting Hong in the first field test
were Richard A. Morin, director of
facilities
for the UB Physiology
Department; Donald R. Wilson, senior
lab equipment designer; Walter S.
Marshall, lab equipment designer, and
Donald R. Rennie, UB professor of
physiology who also 1sa UB vice president and vice provost for research and
graduate education.
M. Steven Piver, M.D., UB clinical
professor of gynecology-obstetrics,
sen·ed as medical director for the testing. Chief of gynecologic oncology at
Roswell Park Cancer Institute, Piver
also serves as vice president of the
board of directors of Friends of the
Night People.
Piver said that during the night
Harmon spent in the corrugated shelter
in a courtyard on the UB South (Main
Street) Campus, "his body stayed as
warm ru; if he was in his own bed."
For his night tn the corrugated pup
tent, Harmon bundled up in a manner
he ~aid reflects that of home le ' S persons
spending a cold winter night outdoors.
He wore two pairs of pant:,, two ,hires, a
sweatshirt, two pairs of socks, a coat,
gloves, and a pair of heavy boots.
- By Sue W111etcher

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24

GOODBYE BUTTER,
HELLO OLIVE OIL
UB researcherssuggestthe switch
could lower the risk of heart disease

mericans intent on lowering their
risk of cardiovascular
disease
would be wise co use olive oil
instead of butter or margarine, according co a major study by researchers at
the UB medical school.
The study, repo rt ed in the Feb. 2
issue of the Journal of the American
Medical Association, represents a major
contribution to the scientific literature.
le indicates chat use of o live oil in the
diet in lieu of butte r and margarine not
only co rrelates with lower blood cholesterol levels, but appears to lower blood
pressure and blood glucose levels.
The UB study is che first large-population examination of the association
between consumption of mono-unsaturated fats like olive oil and risk factors

BY ART HUR PAGE

for corona ry heart disease, according co
Mauri:io Trevisan, M.D., principal
author and associate professor of social
and preventive medicine.
Oche r UB researchers participating
in the study were Vittorio Krogh, M.D.,
Jo Freudenheim,
Ph.D., and Alma
Blake, Ph.D. The Italian researchers
included Paola Muri, M.D., Sal\'atore
Panico, M.D., Eduardo Farinaro, M.D.,
Mario Mancini, M.D., Alessandro
Menotti, M.D. and Gio rgio Ricci, M.D.
The study has received national
attent ion, in part because of the growing interest among the public in hearthealthy eating, but also because the

public relations office at JAMA christened it the prestigious journal's storyof-the-week.
A film crew from the AMA spent a
day in Buffalo, interviewing Trevisan
and filming at local restaurants and
scores to prepare a video chat was distributed co JOO television stations. On
cop of that, the JAMA public relations
office distributed a news release about
the UB study to about 3,000 people.
The landmark study was conducted
in conjunction with Italian researchers
affiliated with the Italian Nine
Communities Study of risk factors for
atherosclerosis. The data, collected by
the Itali an study, was analyzed by the
UB researchers.
Resu Its were based on a n a Iyses of

BUFFALOPHYSICIAS A)',;[) BIOMEl'IC'.Al ~IE.''TIST

�---

:®: ---J'

t ~ ~

2S

data derived from dietary interviews
and physical examinations conducted
with 4,903 Italian adults ages 20 to 59.
The subjects included 2,365 men and
2,538 women.
Trevisan explained that conducting
the same study focusing on the eating
habits of a similar
number of
Americans would have been impossible
on two counts.
First, very little olive oil is consumed
by Americans, although sales have
increased in recent years following
reports on its lmk with reduced cholesterol levels.
Second, Trevisan said, there is very
little regional difference between the
use of fats m the diet of Americans. In
Italy, on the other hand, the researchers
were able to compare data for those living in the northern portion of the
country where butter use is
widespread and little olive oil is consumed - with that for those living in
the south - where olive oil is used
almost exclusively.
"Because of this variation,"
the
authors wrote in JAMA, "we were able
to find relatively strong associations
despite a relatively crude measurement
of dietary intake."
They added, however, that "the
cross-sectional
nature of this study
needs co be taken into account in analysis of the e findings. While the results
are suggestive of a protective role for
unsaturated fats for cardilwascular risk
factors, other unmeasured confounders
may be the actual etiologic agents."
Trevisan said that in their analyses,
the re earchers attempted to identify
such an influence by taking into consideration confounding effect· of other
risk factors for cardiovascular disease,
such as age, body-mass index, alcohol
intake, moking and consumption of
fatty foods.

RCFf-\LO PH)SICI.-\S -\Sl1 BIO\IEl'ICAL ~IESTls.

Maurizio
Trevisan,
M.D.
The study found that "in both sexes,
higher consumption of butter and margarine was associated with increased
systolic and diastolic blood pressures
and increased serum cholesterol levels."
Those associations reached statistical
significance only in men.
"In both sexes, higher frequency of
consumpnon of butter and margarine was
associated with significantly higher levels
of blood glucose," the researchers said.
Increased consumption of olive oil,
they wrote, was associated
with
significantly lower leveb of systolic
blood pressure, blood glucose and blood

choles terol in both sexes. In men but
not in women, diastolic pressure was
significantly neganvely associated with
olive oil consumption.
While the study found that consumption of polyunsaturated fats, such as
vegetable oil, correlated with consistent
and statistically
significant
lower
cholestero l and blood glucose levels,
the association was not consistent for
blood pressure.
Arthur Page is associate director in che UB
News Bureau and farmer medicalreporter at
cheBuffaloNeu·s.

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~

26

Talent in Triplicate
UB alumni are at the helm
of threemedicalschools

BY JUDITH B. HERMAN

"I would say there is no highercal/in~1han
ministering to the sick. But it is useful,
and occasionally importanl, for someone
to be a dean."
- MarshallA. Lichtman, M.D.

orientation and programs for Jevelopmg
faculty to &lt;lo research m academic settings {some of whom may well become
deans), the cltmate m the '50s and '60s
was different, Naughton explained.
"At the time these three graduated,

Sandberg at Roswell Park.
Lichtman wanted to set up an assay
for aldosterone, a hormone that had
recently been discovered to play some
role in hypertension.
Referred co
Sandberg, a hematologist also trained

ith the recent appointment of

the school \\ ' ab very small and pnmanly

in endocrinology,he then began to get

Marshall A. Lichtman, M.O.
'60 as &lt;lean of the University of
Rochester School of Medicine and
Dentistry, the UB medical schlx1l now
boasts three deans among its graduates.
The other two are Eugene M.
Sigman, M.D. '52, Jean of the
Univen,ity of Connecticut School of
Medicine smce 1985, and Franklyn G.
Knox, M.D., Ph.D, '65, who has heen
director for education of rhe Mayo
Foundation and dean of the ~layo
Medical School m Rochester, Minn.,
since 1983.
UB graduate~ achieve dist1nct1on m
many areas. Is it so noteworthy to find
three of them heading medical schools?
John Naughton, dean of the medical
school and vice president for clinical
affairs at UB, thinks it is.
"There arc only 126 medical school
&lt;leans at any one time," Naughton said.
"Prohably most of them come from the
older medical schoob. For Buffalo ro
have three of irs graduates at that level
of recognition 1snoteworthy mdeeJ."
While today UB has a strong research

clinically oriented, with comparatively
lmle facility and faculty to support a big
research endeavor," he said. "Then it
was a matter of bright, motivated people
somehow finding the right connections
and bemg stimulated to do things.
"All in all, there have been a lot of
things done to enlarge opportunities and
create a nourishing atmosphere for UB
students to pursue careers 111 research
and rbe to positions of leadership in academic medicine," Naughton said.
"Sigman, Knox and Lichtman stand
as forerunners and models."

invol"e&lt;l in some of Sandberg's hemologic clinical work.
Sandberg was a major influence and
launched Lichtman's career m hematology, hut Lichtman has tributes for a
numher of UB faculty members.
"l recall with respect and affection
nor only Sandberg, but Oliver P. Jones,
chair of anatomy, who was very actively
involved with students; Douglas Riggs,
chair of pharmacology, one of the best
teachers I ever encountered; Ernest
Wttebsky, Herman Rahn, and Cornell
Terplan, all very distinguished teachers
who developed outstanding departments which provided rich environments for students in terms of research
opportunities," Lichtman said.
Lichtman is the author of research
papers on various aspects of blood cell
biochemistry and physiology and has
been engaged in NIH-supported
research on blood diseases since 1967.
He 1s editor or co-editor of three
textbooks of hematology, including the
recent fourth edition of Hematology
published by McGraw-Hill.

MARSHALL
LICHTMAN
n internationally recognized authority on blood dbeases and the new
dean of the Universit) of Rochester
Medical School, Marshall A. Lichtman,
'60 got his first opportunity to conduct
re~earch when he was a student 111 the
UB medical school.
After his first year, he worked as a
summer research fellow under Avery

IICFMLO r m~K IAS AS I) 111
0 ~1F.l
l1CALSCIENTI:-.,

�-------

:®: -------27

Marshall
A.Lichtman
, M.D. '60
A scholar of the Leukemia Society of
America from 1969 to 1974 and immediate past president of the American
Society of Hematology, he is currently
chair of the National American Red
Cross Biomedical Research Program
Scientific Council.
Lichtman's training as a physician
anJ his activity as a teacher, together
with his work in both basic science and
clinical departments, have been important preparation for his new 106.
"My experience means that I can he
comfortable, say, working with molecular biologists on our molecular medicine

Rlc ff.-\L O PHY'-ll lAS AS[ ) Rl&lt;JME[)I C AL ~ IESTl~T

programs, as well as with physicians in
general medicine on the issues that are
important to them," he explained.
"It's helpful to have had actual experience in all the areas and among all
the various constituencies that look to
you for leadership. It's helpful to have
been in all the trenches."
Licht:man joined the faculty of
Rochester Medical School in 1965.
"I chose to pursue an academic career
because I developed an early interest in
research as well as in patient-care and
teaching," he noted.
Dean of the medical school in

Rochester since January, Lichtman finds
the challenges of his new position are as
varied as the satisfactions are great.
"As dean, I oversee the school's mission in regard to education, research,
and the patient-care activities of our
faculty," he said. "A dean has to set priorities among the different departments
and programs, establish standards for
appointments
and promotions and
adjudicate various disputes.
"But I also have to be a fund-raiser, a
cheerleader and then some kmd of role
model for the faculty."
What makes it so worth while? "I

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:®:--------{/

\t-

28

"I went to medical
schoolto pursue a
careerin research,
not necessarilyto
become a dean,"
saidFranklyn G. Knox.

Franklyn
G. Knox
, M.D
., Ph.D'65
enjoy sccmg to other people," Lichtman
explaineJ. "I thmk that h an important
charactern,t1c of anyone who rakes on
any kmd of leadership position."

FRANK
LYN
G.KNOX
went to medical school to pursue a
career m research, not necessanly
to hecome a Jean," said Franklyn G.
Knox, since 1983director for education
ot the Mayo Foundamm and dean of
Mayo Medical School.
"My undertaking an M.D.-Ph.D. program, hecommg department chairman
and then Jean - none of that was laid
out 111 some sort of master plan at the
hcgmnmg. There was just a general
inclinamm in that direcuon. It JepcnJeJ on hooking up wnh a sympathetic
mentor and the em ·1ronmenr making 1t
possible for those inclmations w tum
mto something."

II

excretion, rena l phosphate handling and
renal hemodynamics - Knox has served
on the scientific advisory board of the
National Kidney FounJation and the
board of directors for the American
One of Knox's first mentors as a UB Heart Association and as president of
for
underii:raJuate was Gerhard Levy, a pro- the Federation of American Sl"&gt;Cieties
Experimental Biology.
fessor of pharmacology. As a UB mediHe has served in numerous capacical stu1dent, Knox workeJ summers in
the lab of DonalJ Rennie, now profes- ties with scientific organizations sor of physiology and vice pro\'ost for national and international - and is
currently on the Nationa l Research
researc:h and graduate education.
"I sQ much enjoyed that kind of Council, U.S. National Committee for
acti\'1ty," Knox recalls. "I said to myself, the International Union of Physiological Sciences.
'If there's any place you'd like to he,
Being dean uf Mayo Medical School
where 1, 1t!' The amwer was the lab."
Undler Rennie's guidance, Knox pur- 1s not the largest of Knox's current
responsibilities. As director for educasued a Ph.D. 111 physiology, as well as an
M.D. The Cllmbined Jegree was neces- tion of the Mayo Foundation, he also
sary, Knox felt, 111order to be able to do oversees the programs and activities of
the Mayo graduate schools in health
basic iresearch m disease-related areas
sciences and medicine.
and ce:ach in a medical school.
Despite his administrative responsiKnox joined the Mayo Medical Schcx)l
faculty in 1971after doing basic rt"l&gt;earch bilities, Knox is able to continue teachmg as he has every year in the medical
at the Natmnal Heart Institute and
,chool for the last 19 years. And, more
reaching at the Univer..1ryof Missouri.
unusual for someone m his position, he
A ditstingubhed anJ highly productive
researcher m the field of renal physiology is able to spend half his time on
- particularly the regulation of sodium research supported by the National

�-------

f!J--------29

Institutes of Health.
Knox's career is something of a balancing act, perhaps, but he is good at it.
"Everything is arrange&lt;l in such a
way that I have been able to maintain
the research and teaching activit ies as
well as carry out my administrative
responsibilities, although at any one
time any of these could be all-consuming," he said. "So it's a matter of organizing and delegating things so everything comes out even."

EUGENE
M.SIGMAN
//

had no aspirations
to go into
administration or to join a fulltime faculty. I just wanted to be like
the rest of the pack, a physician of one
kind or another in private practice,"
said Eugene Sigman, dean of the
Uni,·ersity of Connecticut
Medical
School since 1985.

Eugene
M. Sigman
, M.D
. 'S2

Afteir Sigman finished his residency
and began m practice urology at Buffalo
Genera I Hospital, however, he became
involve·d in research and in 1961joined
che faculty of the UB medical school m
urology. He was awarded Buswell
Fcllows,hips tn 1963and 1964 to pursue
research
in urology and nuclear
medici ,ne and was recruited by the
University of Connecticut m 1969, a
year after the school opened, to head its
urology department.
"I backed into academia from practice," Sigman said. "But l was deeply
interes1ted in medical education, more
than anything else, and that's what
drew me back."
As a new school, Connecticut
offered opportunities to develop innovative approaches
to educat10n,
Sigman said. Courses were multi-discipli narv, based on an organ-syHem
approa,ch, with 10 to 12 faculc} members te:achmg a course. The curriculum

also included courses in the social and
beha\'ioral ~c1ences.
Although Sigman has done important work and written numerous papers
tn urology and nuclear medicine, his
chief interest 1s education. He is a
meml;,er of the Association
of
American
Medical Colleges, the
AAMC Council of Deans, the AAMCAMA Liaison Committee on Medical
Education Site Visit Team and the
AAMC-AMA Oversight Committee
on Me&lt;lical Education.
Sigman traces his own commitment
to educatton to the influence of the
committed faculty and practicing physicians he studied with at UB, including
John H. Talbot, chair of the UB
Department of Medicine and chief of
medicine at BGH; the late Oliver P.
Jones, professor of anatomy, and George
Miller, professor of medicine.
"My own education at UB led me to
appreciate the value of education. The
commitment that [ saw - department
heads taught the basic science courses
- very much impressed me.
"In the clinical years, there was only
a very small full-time faculty. Instead,
practtcing physicians provided free time
for educating medical students. That
really struck me. In spite of their very
busy schedules, they were able to find
time to give to students.
"I took my residency in the same system. I came to see chat what you got
out of the system you had to pay back
by contributing to the education of the
students who followed you. That's probably what impressed me more than anything else about UB. Plus there are a lot
of nice people there."
]11dichB. Hennan is a B1,ffalouriter wah a
special interest m medzcme. She has been a
1niter-ediwr w1th the Western Neu York
HealrhS~swmsAgency.

�---

-/tJ---IJ

\t,

30

ALUMNUS'
GIFTTOUB
HONORS
FORMER
TEACHER
"I will give to my teachersthe respectand
gratitwlewhich is theirdue."
- Oath of Hippocrates
emember chat spec ial teacher who
recognized

your potential,

wh o

encouraged your best efforts, and
who, through h is or her interest and
influence, left a last ing effect upon your

life?
One way co show your respect and
gratit ude is through a gift co the UB
Foundation in honor of that special
teacher and friend.
Jerald A. Bovino '71 recently gave a
$500 gift to the UB Foundation in honor
of his former teache r, Philip Weis '41.
Weis, a clinical professor of surgery, is
a general surgeon in private practice, a
member of the University Council, and
chis year's annual fund chairman.
Bovino wrote:

DearDr. Weis,
I was pleasedto receiveyour recent letter for support for the Unit•ersity at
Buffalo Foundation. I would like w tell
you why your letter has personal
significance.
On a cold and snowy autumn day 23
years ago, I flew to Buffalo for my medical school inten,•iew.Like so many of the
applicants, I was apprehensii•eabout m)'
prospects for acceptance to a school of
medicine. My undergraduategrades were
good but not outstanding, but my MCAT
scores, especially in the sciences, were
very high.
I was mten·iewed by three members of
chef acult:y,but I specificallyremembermy
interniew with you. I felt that you u•ere
warm and sincere,and you made me «•ant
to aLtend the Unit·ersit)' at Buffalo.

Analumnus
remembers
thewarmthandsincerity
shownto himbya teacherat UB.

�---------

~®:--------//

tt.

31

Although I was subsequentlyacceptedto
ocher medical schools, ( many of them
more prestigious), I chose to attend UB
largely on the basis of our personalcontact. . .. A check is enclosedwhich l would
Likeyou to submitfor me in your honor.
Warmestpersonalregards
from a gratefulstudent,
JeraldA. Bovina, M.D.
Bovino rece ived nume rous Mosby
and Lange awards for outsta nding performance while at UB, and was elected
to Alp ha Omega Alpha.
C urrently, he is in a vitreoretinal surgical tertiary care hospital-based practice
in Toledo, Ohio; has published extensively on the subject of retinal surgery;
has se rved as vice president, president
and secretary of the Vitreous Society (a
professional group), and is an associate
clinica l professor of surge ry a t the
Medical College of Oh10 at Toledo .

ship fund will be used for UB medical
studen ts who show academic promise
and have financial need.
"Both my brothe r, Harold, am l myself
ne,·er married or had an y child ren,"
Miss Sanes explained. "We wanted to
do something to he lp others and to
show that we had walked across this
earth. Since our brother taught at UB,
we thought it would be nice to do
something for the Uni\'en,ity."
The late Winfield Louts Butsch '30
is remembered through an endowed lecture fund established in his memory by
h is children, John L. Butsch, M.D.,
David W. Butsch, M.D. and Janet F.
Butsch, and various friends and relatives.
Butsch, a prominent Buffalo surgeon
and clinical professo r of surgery at UB,
died Oct. 24. The gift will be used to
sponsor an annual lecture series in
clinical surgery.

IT'SLAST
CALL
FOR
WORKOF1930GRADS AWARD
NOMINATIONS
GOES
ONTHROUGH
GIFTS
wo graduates of the Class of 1930
who cherished their work with
medica l students are remembered
by gifts that will he lp continue that
work through a scholarship fund and a
lecture series.
The late Samuel Sanes '30, a
noted physician
and professor of
pathology at the UB medical school for
mo re than 30 years, won numerous
awards for his service and contributions
to the field of teaching.
He is remembered through a scho lan,hip fund in the names of his brother
and sister, Harold S. and Thelma, set
up through a gift of $100,000 from
Miss Sanes.
The permanently endowed scholar-

here's just a little nme left to make
n ominations
for the second
annual Distinguished
Medical
Alumnus/a Award.
June 1 is the deadline to suggest a

name of a graduate of the UB medical
school who has made an outsta nding
contribution to medicine, the arts, or
humani ty during his or her career.
The selection will be made during
the summer and the award will be presented in the fall at a special dinner.
There's a postcard at the front of the
magazine for your nominatio n. Hurry!

ERRATUM
Editor:
In the Early Winter 1989 issue, you
have a picture and a short note on a
classmate
of mine, Dr. Har\'ey C.
Slocum. You have it labeled class of '36.
This is incorrect as he graduated with
me m 1932.
He is a renred professor of anesthesia
m Texas. While in the service at Walter
Reed General Hosp ital, he gave the
anesthesia to President Eisenhower durmg his surgery for ileitis.
- Elmer Friedland , M.D. , F.A.C.P.

The Buffalo Physician and Biomedical
Scienast welcomes letters from its readers. Address chem to Buffalo Physician
and Biomedical Scientist, 136 Crofts
Hall. Unit1ersity at Buffalo, Buffalo
N.Y. 14260.

From
leh, Nedra
Harrison,
M.D.'77,
treasurer
of the
MectKal
Alumni
Association,
chats
withShawnCotton
andEllen
Giampofi
oftheOassof
1990at a re&lt;eption
inJanuary
forthe
graduating
doss.
About
250people
attended.

�32

1960.
Paul

J

Loree '62 -

recent!)

1lwrrad1u'
"-:,,,ml •""-x1:ttl,I 111

,,t ,1phth.1l1rniloi:vw11h Kcnncth
Amhonc, M I) m Tort.'lwand,1.
fr,1nl E. Ehrl1d, '61 - 1,
,lin·uor ,,t the di\ 1,10n ,,ftr.Ill•
m I md prof,,, or of urger) .it
Uni\ er 1q in
Hahnemann
rhit.1,ldpht.1 .

D 1\ 1d Ci. l'ublo\\ '65 .- ,,
pre 1clcnr-dect ,11 rhc ;,,.e"
1l 1m1hire Onhop-Jt.•,fa::X&gt;Cll'I)
Lmu,nle A. Gol,lschl,1gcr'65 .1, board ll"rt1hcd in cma.cenq
ml-d1-.mcan&lt;l \\,IS cb:1,-d 11 (cl.
lo" , t 1he Amcncan Collct;c of
Ellll'f)!l"lll\Ph) ll 1,111'.

E.Jordon 't 5 mi:: 11 text book,
Dm:,1sc,oJth&lt;' km

Ro~'fl

t.-dulogic

Roger \X'. Sc1hel '66 .- ha
been named m1er11n clm1-.al
,l1rnrnr ,-it ,urgcn ,It thl· Eric
( ,1111\1\!1.lcJ1l,1ICcnll'r. Dr.
" I •I 1, an ltlcndmg trauma •
•1 I and director of state
11 thl• ho,pttal.
pra,on 'l'r\lll'
,md ,, c11rrcntl, 1clm1c.1I,l,'&lt;X 1•
,Ill' prof, ,,,,rof both ,urger) and
nt UB
or1hClp.1C&lt;l1,,

J,1u1h D. R,,:hrud, 'i l .- 1,
the I\C\\ ,h1cf of orrhop 1cd1c
,uri::cr, Jt Docior, Ho,p1111,
lkth l,r.1d !l.1,d1,.il cl'llll'f,
fork.
~l'\\
1 1
Jame M. L,·\\ 1 ' 5 .pri,,ltl' peJ1.1m, pr llflll' ,111h.1
,pl'll 11mrcr,·,t III dHnllll l lrl'.
Dr I t \\ 1., ha, four lh1ldren

A 11orld tnl\ cll·r, skillc,I pho•
to.gr11lll'r ,mJ ,1 p.11ron of thc
an,, Jlcoh,en Jomcd an,lther
,\ \V1lmo1Jacob.--cn,M I) , 1
doctor on an .ucheologac,tl
I rot,-.,-orol r,·d 1,llrll s ,II U fl
"'
w ,1n·mntc rcg11&gt;1\
t,ir m,1n, ,c,1r, ,,h,"c ,.1r1,·,I cxpcd111lln
II\ 195".
~1cXICll
m1cre,1, m luJed mro1cal,111.!1&lt;"'
of the de 11hof Prcs1dem\V1lh1m
1ed
~hron J. D)hich '
McKmlq, d1,.J D« .. Ii, 19"9,
1989, m ::-dll'ncl.1.1&lt;1\
Ou.lo,
.1ftcr,1hnd 1llnc". lll·\,,is91 .
afrl·r a I, ng I IIn,·~ .
Attn recl.'I\mg ht, h.1chdor's
md mcd1c,1lJq::reo from John,
\ irgmia Pa" lak '36 - \\ ho
Hopl..m, Un1\l:r,11), he ,,·i',d
pr,tl t 1&lt; ,·d medll 11\l'undcr hcr
Ill the u.~ Arn\\ d11rmc\Vnrl,I
m.11,I,11 n,1me of R1.:hrcr. d1l•d
\Vir I tor I\\O ,car, . Atll'r th,·
Jm I , 1990, m Cl ircn ...e. ~ Y,
" ir, he 1rnmc&lt;lan mcd1cmc anJ
J
airer il loni: tllnc,,
pcd1atr1l.,a1 John, Hopkm,.
, M.D.
A. WilmotJacobsen
sl11.•111.11nta1mdhl·r rr1, lie
In 1926, Jncoh,,·n c.11nl·to
c tor 2i \l 1rsunul 19hl,
rrat11
Huttilo r., ,..,1,1hh,hin outra11cm
she bc.:ame d1re.:1or of
"hen
dcronmmr ,11Oul,hn'.. llc,,pnal
d1n1l 1&lt;1rthe E11l l., mtq
In JQ~~. hl' rn,1mcd fael)n
'-he also
I o a peda uric 1an. Health Dl'partmn
Hench,
I H •art
1aui::h1 ar sic
honorl,I rhc
....I _,.. ,I St.,,[Jnt
Children's I ln.i-p11.1l
Ste\ l'll T, 11,:h
Acndl'lll).
thc hr t•
n.unmc
h,
19:-4
p,11rm
,11Ohio
,urcln
of
profr"or
'-tare UntHr•tt) ,111da11,•nJmg tloor ou1p.111en1 d1111l th,
rd Harold MC)cr, ·5-;
"
ph1,11.:1anm the [)q,;1rtmen1 of Jacob-1.'n•Hcath Ambulatoq
ocmx. An:, a P.")l.h1am1,
l lime.
Ped1a1r1csurgcr) m Columbus
3, 1991.l
J1l d J,111.
In thl• I 92l',, J,1.:,,h,cn ,,,1,
l 'luklrcn\ 11.,,pttal.
crcd1tl..J,1uh m1xmi:ii druc from
Tamm) J Lm&lt;ncr - a lir•t•
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P 1ulm, A Wall, ' I - 1
)C3r mro11.:al,1udem, wa, \ailed
OO)"11h memng1115", h1ch ,, as
M,,orkmi: hard" m her prl\ ate
m ,1l,lr ,Kc1Jcm I\:·.:. 21 \\ lllll•
1h,,ught 1&lt;1Ix- t.11,11ll"0 l'l'rH·111
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pr.1lt1u• mt ).1kl.111,l.
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,
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ed 1 8.A m
rcccl\
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to he an earl) f. nn ot ,ulfa drugs,
Jt:ftrq j . !Moua ' 2 - ha,
m 19-.9 from
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the hN an11b1011,
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g t,tr,ll'ntl'mln1.1 ,mJ cndo:,cop1. rnogn1:c ,md Jc,,nl-,c I num•
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Ohituarics

I9SC1-

0

��I(

Buffalo Physician and Biomedical Scientist
State University of New York at Buffalo
3435 Main Street
Buffalo, New York 14214

3581

I

d
n
Requeste
Correctio
Address

II

II
II

I

LOCKIE
DR L. MAXWELL
92.;i DELEWAREAVE
~UFFALO NY 14209

�</text>
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                    <text>Vol. 24, No.2

and Biomedical Scientist

The medical
profession struggles
with maternity leave

�STAFF
DIRECfOR OF PUBLICATIONS
NancyTobm
EDITOR
Connie Oswald Stofko
ART DIRECfOR
Alan J Kegler
WRITERS
Joan Damig
David Htmmelgreen
Jeffery Jackson
Arthur Page
Mary Beth Spina
JeffreyTrebb
Sue Wuetcher
PHOTOGRAPHERS
Debbie Hill
Antoinette Mucilh
Stmon Tong
Robert Walion

ADVISORY BOARD
Dr. John Naughton, Chairman
Dr. Harold Brody
Ms. NancyGlteco
Dr. James Kanskt
Dr. Joseph L. Kunz
Dr. Charles Paganelli
Mr. Michael Aronica
Dr. Antoinette Peters
Dr. Charles Pruet
Dr. Luther Robinson
Dr. Thomas Rosenthal
Dr. Salecla Suresh
Dr. Burton Smgerman
Dr. Stephen Spauldmg
Dr. Nelson Torre
Mr. Edward Wenske
Dr. Jerome Yates

Dear Friends:

T

he.1989-90 academtc year was another busy and producttvf year for the
medtcal school, as evtdenced by the flurry of spring activity. It began wtth
Sprmg Clinical Day, sponsored by the Medical Alumni Association. The
association's efforts culminated successfully with Dr. Arnold Reiman's keynote
address at the Stockton Kimball Lectureship luncheon and an excellent fundraising effort on the part of the five-year reunion classes. The weekend was highlighted by the dedication of a wing in the department of Pathology in memory of
Dr. Samuel Sanes by the Class of 1945 and the presentation of the first Samuel
Sanes Scholarship Award, which was made possible by a generous gift from his
SISter and brother, Thelma and Harold Sanes. We were fortunate and honored
that hiS wtdow, Mildred, participated m the event.
Graduation was highlighted by once agam conducting the Honors
Convocation m the Austin Aint Reading Room of the Health Sciences Library.
An eloquent commencement address was given by MorrtS Abram, United States
Ambassador to the United Nations in Geneva. His remarks were enlightening
because of his own experiences wtth acute leukemia in the mid-1970s.
The third annual reception honoring and recognizing the many contributions
of the volunteer faculty was held at the Albright-Knox Art Gallery.
Approximately 200 faculty and their spouses attended.
The second annual Graduate Medical Dental Education Consortium dinner·
dance completed the Spring's activities on June 22. Each resident graduate
received a set of bookends with the UB logo on one and the consortium's title on
the other.
We look forward to an even more exCiting and productive academic year m
1990-91. As always, the staff and faculty are grateful for the tremendous support
provided by our alumni and friends.

TEACHING HOSPITALS
AND LIAISONS
Batavia VA Medtcal Center
Buffalo General H&lt;l&gt;'[Htal, Mike Shaw
Buffalo VA Medical Center, John Pulli
Children's Hospital,

Karen Oryja-Swierski
Ene County Medical Center
Mercy Hospttal, Chuck Telesco
Millard Fillmore Hospttal,
Joseph R. Ciffa
Roswell Park Cancer Institute,
]wl.y Rice
Sisters Hospital, Dennis McCarthy
Produced by the DitJisum of Unit'f'TSity
Relations in association uith the SchOOl
of Medicine and Biomedical Saences,
~rate Unit'f'TSity of New York al Buffalo.
Editorial office is in 136 Crofts Half
THE BUFFALO PHYSICIAN AND
BIOMEDICAL SCIENTIST (USPS
55I-860) Autumn 1990, Volume 24,
Number 2. Published by the School
of Medicine and Biomedical
Sciences, State University of New
York at Buffalo, 3435 Main Street,
Buffalo, New York 14214. Third
class bulk postage paid at Buffalo,
New York. Send address changes to
THE BUFFALO PHYSICIAN AND
BIOMEDICAL SCIENTIST, 146
CFS Addition, 3435 Main Street,
Buffalo, New York 14214.

John N aughton, M.D.

Vice President far Clinical Affairs
Dean, School of Medicme and Biamedical ScienCes

Dear Fellow Alumni/Alumnae:

T

he spring of 1990 marked the anniversary of the 53rd year of Spring Clinical
Day. In my opinion, this event has been marked by ever-increlli&gt;ing maturity
and sophistication for which all alumni can be justifiably proud. The clini·
cal and reunion weekend provtdes a major focus for your Alumni Association
and this year's program was especially timely, informative, and prognostic.
As your new president and on behalf of all medical alumni, I would like to
express our appreciation publicly to Dr. Bob Reisman, Class of'S6, for assembling
such a superb program. Our outgoing president, Dr. Joe Kunz, served his term
with distinction and our gratitude goes to him as well. I would be most remiss if I
didn't communicate to all of you how grateful we are to Dr. Jack Richert and to
Nancy Druar of the Alumni Office. Without their help and guidance, this asso·
ciation would be a far less healthy organization.
I look forward to servmg as your prestdent and I hope to continue ro work
actively with alumnt, medical students, faculty, and administration as we all work
to support and strengthen our medical school.

Sincerely,

D~

Bertram A. Portin, M.D.
Class of'53

�Autumn 1990

Vol. 24, No.2

IJ Research. A $4.5 million grant to study treatment
of multiple sclerosis; AIDS fear and drop in blood
transfusions; diving for science.

II Mommy track? The number of women attending
Cover: Photos by Robert
Walion. Story starts on
page 6.

medical school has steadily increased, but is there
room in the system for their babies, too? UB
women discuss the problems and pressures they've
faced balancing family and profession.

IIJ Cutting red tape. American doctors have the power
to change the medical delivery system in this
country, said Arnold S. Relman, M.D., editor,in,
chief of the New England Journal of Medicine. He
spoke at UB's 53rd Annual Spring Clinical Day
and Reunion Weekend.

Ill Rubbish. From hypodermic needles to patients'
Orientation follows gradWltion. Page 26.

facial tissues, the amount of medical waste is
growing daily, and it's getting harder to throw the
stuff away.

~~ Medical school news. How a 19th,century anatomist
got tangled up with couple of body snatchers was
the topic of a lecture sponsored by Alpha Omega
Alpha. At commencement, diplomat Morris
Abram told graduates to "listen with heart." And
Match Day was better than ever.

m

People. Marvin I. Herz, M.D., chair of psychiatry

at UB, got a new perspective on the workings of
Washington bureaucracy.

America's ailing medical system.

IIJ Classnotes.

Page 13 .

Trashing medical wastes.
Page 20.

�: --------------------------------------------

2

UB Takes a $4.5 Million Shot at MS
UB research pioneer heads team investigating
treatment for disease that hits young adults
BY ARTHUR PAGE

0

ne of the largest grants ever
received by the UB medical
school will study a promising
treatment for multiple sclerosis, the
most common crippling disease of
young adults.
The four-year, $4.5 million federal
grant from the National Institute of
Neurological Disorders and Stroke was
announced in May. UB is the coordinating center of the multi-center study
that will involve 288 patients at
Millard Fillmore and Buffalo General
hospitals in Buffalo, as well as hospitals
in Washington, D.C.; Cleveland;
Denver, and Portland, Ore.
It will evaluate the effectiveness of
intramuscular injections of beta interferon in the treatment of a form of multiple sclerosis characterized by alternating periods of flare-ups and inactivity.
Results of the study could lead to the
approval of the experimental treatment
by the U.S. Food and Drug Administration, according to Lawrence D.
Jacobs, M.D., principal investigator and
UB professor of neurology. There currently is no effective treatment for multiple sclerosis, which affects an estimated 250,000 Americans.
Jacobs has gained international recognition for pioneering work showing the
effectiveness of beta interferon injected
intrathecally, or into the spinal fluid, in
treatment of multiple sclerosis patients
with exacerbating-remitting disease. His

AUTUMN 1990

co-investigator on the new study will be
Frederick E. Munschauer Ill, M.D., UB
assistant professor of neurology.
The study will involve patients at the
William C. Baird Multiple Sclerosis
Research Center of Millard Fillmore
Hospitals, of which Jacobs is chief, and
the Buffalo General Hospital, where he
is head of the department of neurology.
Other participating centers include
the Mellen Multiple Sclerosis Center of
the Cleveland Clinic, Cleveland, Ohio;
Walter Reed Army Medical Center,
Washington, D.C.; University of
Oregon Medical Center, Portland, Ore.;

and University of Colorado Health
Science Center, Denver.
Carl V. Granger, M.D., UB professor
of rehabilitation medicine, will serve as
a consultant on the project. He also is
co-director of the Bernard B. Hoffman
Multiple Sclerosis Center at the Buffalo
General Hospital and chief of rehabilitation medicine at Buffalo General.
Data management and statistics will be
coordinated by scientists at UB and
Roswell Park Cancer Institute, under
the direction of Diane Cookfair, Ph.D.
Jacobs has been investigating the use of
beta interferon to treat individuals with
multiple sclerosis since the late 1970s.
His work and that of others using
beta and other forms of interferon - a
substance produced by the human
immune system to fight viral infections
- is based on, and reinforces, a growing body of scientific evidence that
multiple sclerosis is caused by a viral
infection that is not effectively countered by an individual's immune system.
In two earlier studies, Jacobs and colleagues showed that treatment with
beta interferon given by spinal taps
reduced or prevented exacerbations in
patients with exacerbating-remitting
multiple sclerosis.
Follow-up analysis of the patients in
the first study showed beneficial effects
persisting in some patients for up to five
years after treatment.
The second study, in conjunction with

BUFFALO PHYSICIAN A D BIOMEDICAL SCIENTIST

�: -----------------------------------------------

3

researchers at the University of Rochester
Medical Center and at Walter Reed Army
Medical Center, was considerably larger
and double-blinded, with neither participants nor researchers knowing which
patients received interferon or placebo
treatment. At the end of the controlled
study, the disease flare-ups of those who
received beta interferon had been significantly reduced, compared to those in the
control group receiving placebo treatment.
The clinical condition of three-fourths of
69 patients who received interferon was
improved or unchanged. In some cases,
symptoms disappeared and patients
regained lost functions.
Jacobs said those studies focused on
intrathecal administration of beta interferon because it was believed the substance did not cross the blood-brain barrier and that the only way to get it into
the central nervous system was by injection directly into the spinal fluid. He said
subsequent studies in animals have shown
the same positive changes in the immune
reactivity of the central nervous system
whether beta interferon was administered

BUFFALO PHYSICIA

AND BIOM EDICAL SCIENTI ST

by spinal tap or intramuscularly.
As a result, his focus is now on intramuscular injections. "Even though the
intrathecal injections worked and were
well tolerated by patients, people don't
want to undergo multiple spinal taps if
they can avoid it," Jacobs added.
Participants will be assigned randomly
to two groups -- 144 will receive weekly
intramuscular injections of interferon
over two years, and 144 will receive intramuscular injections of a placebo once a
week for two years. All participants will
be followed for two years following their
last injection. The study will be
double-blinded.
Researchers affiliated with a
multi-center study at the University of
Maryland are conducting a similar study
with intramuscular injections of beta
interferon. However, there are important
differences in the studies.
Participants in the Maryland-based
study receive injections of larger doses of
beta interferon three times per week,
while those in the UB study will receive
substantially lower doses only once a

Lawrence D. Jacobs, M.D., principal investigator, is
studying a treatment for MS.

week. Jacobs noted that the UB study will
utilize substantially lower doses of beta
interferon based on a pilot study by his
group that indicated the lower dose given
once a week will produce the same
immunological response as higher doses
given thrice weekly.
In addition to monitoring participants
for exacerbations of their disease, the UB
study also will assess progression of disease
and disability.
Jacobs noted that multiple sclerosis
"most often affects individuals at or near
the peak of their productivity and consumes substantial societal and health care
resources. Fifty percent of patients with
multiple sclerosis will be unable to walk or
conduct normal work activities within 10
years of disease onset."
In addition to previous support from
the National Institutes of Health, Jacobs'
earlier studies were supported locally by
the Baird Foundation; William C. Baird
Multiple Sclerosis Research Endowment

AUTUMN 1990

�:--------------------------------------------

4

of the Millard Fillmore Health, Education
and Research Foundation; Millard
Fillmore Hospitals; Delaware North
Corp.; )arne H . Cummings Foundation;
the Buffalo General Hospital and the
Bernard B. Hoffman Foundation.
The late t grant "underscores the
commitment to excellence in clinical
neuroscience of the UB medical school
and its department of neurology," said
Michael Cohen, M.D., UB professor and
chair of neurology. "In granting this
award, the NIH ha firmly recognized
Buffalo as a center of excellence in neurologic research.
John P. Naughton, M.D., UB vice
pre ident for clinical affairs and dean of
the medical school, said that while
Jacob provided the initiative for the
study, "the cooperation of Millard
Fillmore and Buffalo General hospitals
provided an impetus for getting this off
the ground. It's an example of the kind
of thing that the medical school can do
with affiliated teaching hospitals in the
community, with each maintaining its
unique focus while coming together for
common research projects."
Care of people with multiple sclerosis
in Western New York is coordinated
through the University at Buffalo
Multiple Sclerosis System, formed two
years ago under the auspices of the UB
Medical School and its departments of
neurology and rehabilitation medicine.
The program unifies the services of the
William C. Baird Multiple Sclerosis
Research Center of Millard Fillmore
Hospitals, the Bernard B. Hoffman
Multiple Sclerosis Center of Buffalo
General Hospital and the Western New
York Chapter of the National Multiple
e
Sclerosis Society.
Arthur Page is associate director in the UB
News Bureau and former medical reporter at
the Buffalo News.

AUTUM

1990

DROP IN TRANSFUSIONS
LINKED To AIDS THREAT

F

ear of AID has decreased not only
the amount of blood collected in
the United States, but also the
amount physicians use, researchers at
UB and the Center for Blood Research
have determined.
The researchers, reporting in the June
7 issue of the New England journal of
Medicine, found that blood transfusions
have declined significantly since 1984,
suggesting that physicians and surgeons
are altering their practices.
The findings of the research team, led
by Edward L. Wallace, professor of management sy terns at UB, and Douglas M.
Surgenor, M.D., senior investigator at
the Center for Blood Research in
Boston and former dean of the UB medical school, were based on national surveys of transfusing and blood-collecting
activities in the United States in 1982,
1984, 1986, 1987, and 1988.
The findings indicate that some
transfusions performed in the past may
have been unnecessary, particularly
those single-unit transfusions that are
given to patients to make them feel better, Wallace noted. Physicians and surgeons now seem to be weighing more
carefully the risk of not giving a transfusion versus the risk of transfusing a
patient with blood that may be infected
with HIV or other transfusion-transmitted infections, he added.

"Patients, blood donors and the public at large are apprehensive about the
safety of the blood supply, about acquiring AIDS through blood transfusion
and even about the safety of donating
blood," the researchers said.
"Physicians, increasingly aware of the
risks of HIV and other transfusiontransmitted infections, are reconsidering
the risks and benefits of transfusions,
and are turning to alternatives to transfusion of homologous blood, including
not transfusing at all."
Transfusing fewer units of blood is one
way of reducing the risk of contracting
AIDS through transfusions, but the risk
is already low, Wallace said.
In the national surveys of blood transfusing and collecting activities, Wallace
and Surgenor found that transfusions of
whole blood and red cells peaked at
50.6 units per 1,000 population in 1984
and fell to 4 7.6 units per 1,000 in 1987.
Collections of homologous blood
(donated for use by other people) was
growing rapidly until 1982, when the
growth slowed. Collections peaked at
13.4 million units in 1986 and declined
to 13.2 million units in 1987, the
researchers found.
Meanwhile, collections of autologous
blood (blood to be used by the donor
him elf) -- less than 30,000 units in
1982 -exploded to 397,000 units in
1987. That's equivalent to 3 percent of
the homologous collections that year.
The researchers concluded that the
unprecedented decline in transfusions,
coupled with the importation of packed
red cells from Western Europe and the
effect of autologous collections, forestalled
serious shortages of blood due to the lackluster collections of homologous blood.
Other re earchers contributing to the
study were Steven H. S. Hao, M.B.A.,
of UB and Richard H. Chapman of the

BUFFALO PHYSICIAN A D BIOMEDICAL SCIE TIST

�------------------------------------------- -

: --------------------------------------------

s

Center for Blood Research.
The research was funded by a grant
from the National Heart, Lung and
Blood Institute. The grant, in its fifth
year, will be continued for another five
e
years, Wallace said.

- By Sue Wuetcher

DIVERS IN UB CHAMBER
HOLD THEIR BREATH
IN NAME OF RESEARCH

W

hen the Majorcas hold their
breath, it's worth studying.
The family team of deep
breath-hold divers from Italy took part in
tests at UB's Center for Research in
Special Environments as part of a
research project under the direction of
Claes Lundgren, M.D., Ph.D., professor
of physiology and director of the center.
Data from tests in the chamber will
provide scientists with information on
changes that occur when the body is subjected to increased pressures in the

BUFFA LO PHYSICIA

AN D BIOMEDICAL SCIENTIST

ocean's depths. That promises to improve water safety techniques for divers
as well as benefit patients who have
heart arrythmias and other heart-lung
problems.
Pressure on the body increases as
divers go deeper. If a breath-hold diver
stays down too deep for too long, he
could lose consciousness and die. At
greater depths for more than a minute,
pressure can compress the lungs, forcing
blood into the heart and lung capacity,
causing internal bleeding and severe cardiac arrythmias.
The Majorcas-- Enzo, 58, and his
daughters Patrizia, 30, and Rossana, 32, are athletes who hold their breath for two
or three minutes as they dive to depths of
150 feet or more in quest of world records.
A sport in Italy since the 1930s, champions of early deep breath-hold diving contests claimed their prize money from an
underwater cage placed by weights at a
depth that proved a record-setting dive.
Enzo Majorca, record-setting diver, floats in UB's
hyperbaric chamber.

Enzo still holds the record, set in 1976, for
the deepest unassisted breath-hold dive of
197 feet.
In "assisted dives," the athletes are
lowered to the ocean's depths on a small
platform. The divers use a lever to control their rate of descent, explained
Massimo Ferrigno, M.D., who was instrumental in arranging for the Majorcas to
be tested at UB.
"They hold their breath only the two
or three minutes it takes for them to
enter the water, reach the desired
pre-determined depth for a record and
then ride the platform back to the surface," explained Ferrigno, an anesthesiologist and a former UB Buswell Fellow.
The three divers' work at UB took
place underwater in the environmental
chamber, which has the widest pressure
capacity of any in the western world,
simulating the pressure of 5, 700 feet
underwater to 100,000 feet in altitude.
The divers were allowed to go only to
the equivalent of 240 feet in the chamber for safety reasons, said Lundgren, and
the Majorcas were in full control of their
rate of descent.
The research team also is studying how
water depth relates to triggering of the
mammalian diving reflex that has saved
people who fell into icy waters. While
the coldness of the water constricts
peripheral blood vessels, diverting available blood supply to feed vital organs
such as the brain or heart, there may be
other changes which the pressure of the
water may trigger.
Italian scientists and physicians in
Buffalo as part of the research team were
Paolo Cerretelli, M.D., Guido Ferretti,
M.D ., and Mario Costa, M.D. The
research project with the Majorcas is
funded by the National Oceanic and
Atmospheric Administration through
the New York Sea Grant Institute.
e
- By Mary Beth Spina
AUTUMN 1990

�6

~MMY~ACK
IN MEDICAL SCHOOL?

y years ago, few women's faces

women in their prime childbearing

looked out from med school year,

years, medical schools and women

books. Then, in the 1970s, barriers

have had to face a difficult issue -

to traditional male professions began

time off for pregnancy and maternity

to fall, and today women repre,

leave. These stories look at

sent more than a third of UB's

the problems and pressures

medical school classes.

and how some UB women

With the arrival of so many

By
AUTUM

1990

D ebo r a h

have dealt with them.

Willi a m s

BUFFALO PHY !ClAN A D BIOMEDICAL SCIENTIST

�7

Usa Benson, M.D. '88, spends some quiet time with daughter Eve Guterman. ult's a tough situation, 11 Benson says of maternity leave.
ulosing a resident for any length of time can be difficult and we are sensitive to our peers and their work loads.11

Photos by Robert Walion

BUFFALO PHYSICIA

AND BIOMEDICAL SCIENTIST

AUTUMN 1990

�9QUGH ~EING
9 HORT-STAFFED
8

t one time, Lisa Benson, M.D., a
1988 UB medical school graduate
and third-year resident in
medicine, considered ob-gyn. But
because she wanted to combine a medical career with a family, he decided she
didn't want those long hours.
Benson, 28, had her first child in
September and returned to her residency training in April. Her husband, Lee
Guterman, M.D., is a resident in neurosurgery.
"Initially I intended to only take six
months, but there were complications
with my pregnancy and my daughter
was born early," she explained. "I never
thought of only taking ix weeks off. It
was an in tinctive thing with me. I just
couldn't leave my daughter o soon.
"As soon a I knew I was pregnant I
let my director know so preparations
could be made for my ab ence. When
we are short-staffed because people are
out on maternity leave there are comments from some residents. It's a tough
situation - losing a resident for any
length of time can be difficult and we
are sensitive to our peers and their work
loads. My training will take longer but
~
that's OK."

g 'TRUGGLE IS
Jf OTHING EW

discrimination against women in obtaining residencies then, but with the war
and the men, including my husband,
being sent overseas, I got the residency."
Henrich took 10 years off to have her
children, but kept her hand in the field
by doing some clinical work.
'W

q?HILD ~ARE
fZIFFICULTIES
Mary Henrich, M.D., displays photos of her sons

"I'll just stay right
at the hospital and
have my child and
be back at work
three weeks later.
I wouldn't recommend
.
"
zt. to my patzents.
- Ortman--Nabi

J/

he problems women doctor face
trying to combine family and
career are nothing new. Mary
Henrich, M.D., struggled with them
half a century ago.
A 1941 UB medical school graduate,
she was one of only four women in her
class. She met her husband, the late
Daniel Bot ford, M.D., in medical
school, and wanted to have a family.
"I very cold -bloodedly chose ophthalmology as my specialty because I
decided I could control the hours and it
would combinr well with raising a family," explained Henrich, 74.
"Then I faced the problem of getting a
residency in the field. There was definite

AUTUM 1990

Judy Ortman·Nabi, M.D., and her daughter, Jasmine

udy Ortman-Nabi, M.D., 34, who
has struggled with a system that
didn't work for her, supports the call
for changes. She is a second-year resident in obstetrics-gynecology and a
1989 graduate of the UB medical school.
She was a first-year medical student
in Ohio when she had her daughter.
Her husband, Hani Nabi, M.D., was
living in Seattle.
"It actually worked out fairly well
because at least I had the summer off,
but it was difficult going back to school
and caring for my daughter with my
hu band so far away," Ortman-Nabi
recalls. "Then my daughter had to be
hospitalized for respiratory problems."
Family members, including one who
is a nurse, were able to help care for the
child, but that meant the girl had to be
taken to their homes, a four-hour drive.
"My husband took her the next year,
but he had a great deal of difficulty with
child care," Ortman- abi said. "It was
very complicated and I ended up taking
a year off from school. We moved to
Buffalo where I fini hed medical school.
I've continued to have problems finding
reliable child care and my husband travels about one week out of every month."
As Ortman-Nabi related her experiences, she was busy arranging for interviews for someone to care for her second child, who was expected shortly.
"I'm doing my rotation at Children's
right now and I'll just stay right here at
the hospital and have my child and
hopefully be back at work three weeks
later," she said.
"It's not something I would recommend to my patients. I'm just taking
vacation time. The program that I'm in
really isn't flexible. The system definitely needs to change."
~

BUFFALO PHY !CIA AND BIOMEDI AL

IENTIST

�-

9 UPPORTIVE
q?OLLEAGUES [7?ELPED
or Heidi DeBlock, 27, who graduated from the UB medical school this
spring, life as a medical student and
new mother worked out a lot better
than she had expected. Despite taking
six weeks off during her pregnancy and
three months after her daughter was
born a year ago, she graduated only a
month late.
"I had some extremely supportive and
kind attendings who helped," she said,
"except for one who asked me whether
my pregnancy wasn't all a big mistake. I
was quite sick during my pregnancy and
even had to be hospitalized.
"My husband is a pastoral counselor
in area hospitals and a minister in
Rochester. He commutes there several
days a week but he's off on Monday and
watches her then, and the other days
she's in day care. I nursed her for quite a
long period and during days when I was
on a surgery rotation from 6 a.m. to 9 or
10 at night my husband would bring
her to the hospital or sometimes I
would go to her."
DeBlock plans to specialize in internal medicine and spent May working at
the Johnson Space Center. She took
her daughter with her and her husband
joined them for a couple of weeks. She
wants three or four children and is
planning the next one at the end of her
third year of residency.
"I think it would be too difficult to be
pregnant earlier, especially if I am sick
again," DeBlock said. "I thought about
picking a specialty that would work out
well with a family but I decided I had to
go with what I liked. Hopefully, there
will be part-time positions for me." ~

Heidi DeBlock, M.D., with daughter Alexandria

"I have been able to
combine medical
training and
motherhood. I don't
have any free time,
but it can be done
if you want to. "
-Brown

q lD 9

URGERY AT
'llTH :JCOUR'
essica Brown, M.D., 35, an orthopedic
surgeon who graduated from the UB
medical school in 1984, was doing
surgery right up to three weeks before her
daughter was born three years ago.
It's still relatively rare for women to

BUFFALO PHYSICIAN AND BIOMEDICAL SCIE TIST

Jessica Brown, M.D., and her daughter (orina

enter the field of orthopedic surgery and
ra rer yet for a resident in orthopedic
surgery to be pregnant.
Brown was able to do both because of
the support she got from Robert Gillespie,
M.D., chairman of orthopedics, she said,
adding, "I think I had an easy pregnancy
and delivery because I'm a jogger and also
lift weights, which l continue to do whenever I can."
Brown said she didn't consider the specialty's effects on raising a family; she chose
orthopedics because she liked it.
"I didn't want to compromise my
career," she said. "But once I'm in private
practice my hours will be more controlled
since many orthopedic surgeries are elective and scheduled.
"l took eight weeks off when my daughter was born, and with the support of a
good babysitter and my husband, who is a
Marine recruiter, I have been able to combine training and motherhood. I certainly
don't have any free time, but it can be
~
done if you want to."

q/(AITED10

~VE ~HILDREN
rucy Borowitz, M.D., 36, clinical
assistant professor at UB, said she
waited to have children until after
her residency because she felt it was just
too hard to combine both.
"I've had a zigzagging career which has
included study and work in various cities
around the country," she said. "But I've
always worked part time including when I
was in private practice. Right now I am
supposedly working 80 percent time,
although it is probably more than that."
Borowitz is director of the Cystic
Fibrosis Center at Children's Hospital,
mother of two children, ages four and six,
and wife of Philip Glick, M.D.
"This is a creative country and certainly programs could be developed to accommodate the needs of physicians and their
families," said Borowitz. "It's unlikely that
l will climb the academic ladder, but that
has been my choice. Medicine is really a
wonderful profession and I have been
able to combine my family with intellectually stimulating work."
~

AUTUMN I990

9

�10

Susan Graham, M.D., holds her son Peter

._qRAYS A .c71AzARD
IN d'JREGNANCY

S

usan P. Graham, M.D., 36, assistant
professor of medicine at UB an~
director of the Coronary Care Umt
at Buffalo General Hospital, faced the
problem of protecting herself against
X-ray exposure during her pregnancy.
"I was pregnant and in my third year of
a fellowship in cardiology and the official
policy was that pregnant women were not
to be anywhere near X-rays," she
explained. "But I was working with
angiograms, so I took extra precautions. I
wore extra lead shields and wore a radiation badge to detect any radiation."
Graham had her first child last summer
soon after coming to Buffalo. Her husband, Jon Kucera, M.D., is an internist on
the staff of Health Care Plan.
"I worked up to the day I delivered. In
fact, it was a Saturday morning and I was

AUTUM

1990

making rounds. I was feeling pains and
went home and waited for my husband
who had also been making rounds. I
ended up arriving at the hospital just an
hour before I delivered my son. I took off
six weeks after he was born."
Graham says she feels under pressure to
do research and publish to advance her
academic career, but right now research
has to have the lowest priority in her life.
She will continue teaching as a clinical
professor if she finds it's just not possible to
advance on the traditional academic ladder. "Hopefully, I will find the time to do
research, but there are limits to the day
and one's energy," Graham said.
e

qHE f?'YSTEM IS
fNHOSPITABLE 1D
~(OMEN ANDdfABIES

Ill

he system (of medical education)
has failed to adequately address
the needs of women physicians
who also want to raise a family," said

Linda Brodsky, M.D., assistant professor
at UB and co-director of pediatric otolaryngology at Children's Hospital.
"Women face the real issues of their
biological clock and a system that really
hasn't been able to accommodate their
needs."
The system's many critics argue that it
hinders women who want to combine a
medical career with family. Obstacles
include a lack of flexibility in training
programs, long hours which make
breast-feeding difficult, rigid timetables
in academic medicine, difficulty in finding part-time positions, and a general
shortage of reliable day care.
Nationally, women make up more
than a third of medical school students
and nearly a third of residents, according to Anne E. Bernstein, M.D., director for members-in-training of the
American
Medical
Women's
Association and professor of clinical
psychiatry at the Columbia University
College of Physicians and Surgeons.
Two-thirds of practicing women
physicians have children. Half of them
had their first child during residency
training and one-quarter had their second child during that period. Bernstein
added that few women reduced their
working hours during pregnancy.
Women physicians have been struggling for a long time with the issue of
maternity leave policies, said Glenda
Donoghue, M.D., APFME director of
Continuing Medical Education and
Professional Development at UB and a
director of the National Council on
Women in Medicine.
"There are certain limitations inherent
in the education system," explained
Donoghue, who is also co-chair of the
Committee on Academia of the
American Medical Women's Association
and served as chairman of the Committee
on Women in Medicine of the Medical
Society of the County of Erie.
"Residents must work for a set period
of time before they can sit for their
boards and there is a similar limitation
in medical school. Thus eight weeks is
probably the outside limit (for maternity leaves) without extending the training period."
At UB, the majority of women medi-

BUFFALO PHYSICIA

AND BIOMEDICAL SCIENTIST

�cal students and residents who choose
to have a baby during training are able
to take time off and get back on track
within a year, according to Maggie S.
Wright, Ph.D., assistant dean for student affairs at UB medical school. Most
request eight weeks off, although some
take less time and others more.
That agrees with the national statistics, according to Bernstein, who said
women take an average of between two
and eight weeks.
While schools should have written
leave policies, Bernstein wrote in the

11

Journal of the American Women's Medical
Association, there aren't enough facts to
decide how long that leave should be.
The data does suggest that a maternity
leave of six weeks is recommended for
recuperation from noncomplicated
pregnancy and delivery, she noted.
"We also feel strongly that while
maternity or child care leave is not a disability unless there are medical or surgical complications, the housestaff member taking a sanctioned leave is entitled
to reimbursement just as if she had sustained a fractured leg," Bernstein said.
But residents who seek leaves because
of pregnancy create real problems with
scheduling and with other residents,
noted Margaret McAloon, M.D., clinical associate professor of medicine at UB
and medical director of the University
Medical Practice Services P.C.
"Someone has to pick up the work
and it's natural (for other residents) to
resent having to work harder,"
McAloon said. "Right now there aren't
any part-time programs that could
accommodate pregnancy and child
rearing more easily. Pregnancies during
residencies definitely play havoc with
schedules, especially when three or four
women are pregnant at the same time."
The system still has its problems, but
McAloon notes that some attitudes
toward women physicians and their
families have improved over the years.
"When I was applying for residency
programs in the late '60s, I actually was
asked about what form of birth control I
was using," she recalled. "Of course, I dismissed applying for those programs after I
was asked those questions. No one would
dare ask anything like that today."

BUFFALO PHYSICIA

AND BIOMEDICAL SCIE TIST

Undo Brodsky, M.D. with her children Jeremy, left; Dana, right, and Rebecca, foreground

A number of suggestions have been
offered to help physician-mothers. These
include part-time and shared residency
programs, longer parental leave programs,
a flexible approach to the tenure clock,
and improved day care options.
"I think the idea of the 'mommy or
daddy track' is a great one," said
Brodsky, a 3 7-year-old mother of three
children, ages seven, five and two years.
"By this I mean a more flexible system
that would be available to all physicians
who want to have more time for their
families and still pursue academic
careers."
She decried the "arbitrary timetables"
that exist in academic medicine and
believes academic medicine imposes the
greatest demands on physician-mothers.
"I was very lucky with each of my
children - uncomplicated pregnancies," Brodsky said. "I took a month off
for each and breast-fed for six weeks, but
all women pay a great price. They are
often constantly tired and worn-out."
Brodsky, whose husband, Saul

Greenfield, M.D., is head of pediatric
urology at Children's Hospital, said she
has been able to balance the conflicting
demands of her many roles only with reliable full-time live-in household help, plus
two part-time assistants at home.
Writing in a November 1989 New
England Journal of Medicine essay, Carola
Eisenberg, M.D., a Harvard Medical
School psychiatrist, argued for more
choices for both women and men. She
supports parental leave and day care programs throughout medical school, residency training and employment.
She also calls for stopping or slowing
the tenure clock in academic medicine
while doctor-parents take off to bear and
rear children.
"Women will bring into academic
medicine a greater emphasis on the
importance of the physician's family life,"
she wrote. "The beneficiaries of this concern will be men as well as women ....
Restructuring medical careers to recognize the legitimate needs of physicians'
families will be to the advantage of all."'i'

AUTUMN 1990

�~·

·~ .
· .....,. , ;;..«. :

�for America's Ailing
Medieal System

8\' CO,~lE OSW.\LD ~OFKO

Today's
doctoring
is no Norman
Rockwell scene

Their hands may be tied with red tape, but
American doctors have the power to break those
binds by helping to change the medical delivery
system in this country.
That was the common thread weaving through
talks at the 53rd annual Spring Clinical Day

•

-..

sponsored by UB's Medical Alumni Association.

--

theme of the session held April 28 in the Buffalo

-

•

I

"Changing Aspects of Medical Practice" was the

Marriott Hotel.

�'PAYORS' REVOLT'
SPAWNED RED TAPE
I I D octors are right in perceiving
that there are increasingly
intrusive and harassing restrictive conditions being put on the freedom to practice," affirmed Arnold S.
Reiman, M.D., editor-in-chief of the
New England Journal of Medicine and
considered by some to be America's
most powerful doctor.
Despite the red tape that makes doctors' lives miserable, "medicine doesn't
need more micromanagement," said
Reiman, who advised his colleagues "to
recognize the problem and participate
in the solution." Physicians need to
work actively toward a system that lowers costs, regains the public's trust, and
delivers care to all citizens.
"Let's stop fighting managed care and
quality assurance," said Reiman, who
advised doctors to enforce quality control, rather than fight it. That would
get the malpractice monkey off doctors'
backs, he said.
The seeds for the restrictive climate
were sown after World War II, Reiman
said, when medical facilities expanded
rapidly and specialties became more
sophisticated.
As health care became more available and more expensive, third-party
indemnity-type insurance became popular. By the late 1960s, roughly 85 percent of American had some kind of
health insurance, usually through their
employers or through Medicare and
Medicaid.
Businessmen could build hospitals,
make it attractive for doctors to practice there, accept only the in ured, and
charge what the market would bear.
There were no incentives for consumers
to keep costs down, and there were
enormous incentives for doctors to provide services, the]oumal editor said.
"You had the inevitable ingredients
for enormous inflation," Reiman said.
This led to the revolt of the payors.
"When Mr. Iacocca (the head of
Chrysler) has to pay $700 per car that he
manufactures to pay for his workers'
health care coverage, he's not happy; he
doesn't like that; he didn't choose to do

~.:~~·
.-,.JSJ),
. ·~

·~·

~

"It's a thinly
disguised, sanitized
version of the
kickback. It's an
example of what's
happening in the
conversion of health
care from a
social service
to a commodity. "
that," Reiman said. "He was taken kicking
and screaming into that arrangement."
Uncle Sam is just as unhappy to pay
approximately 8 percent more each
year for physician services for Part B
Medicare, Reiman added. In addition,
the public has doubts about the quality
and necessity of the tests and procedures doctor are performing.
All of this is driving payors to insist
on more and more regulations to control costs and increase effectiveness,
said Reiman.

Doctors are responding by seeing
themselves as businessmen: doctors
making extra profit by dispensing drugs
in their offices; ophthalmologists buying a certain brand of lenses at a discount and charging the insurance company full price; doctors investing in
facilities to which they refer their
patients- the more patients they refer,
the bigger their profit.
"It's a thinly disguised, sanitized variation of the kickback," Reiman said.
"It's an example of what's happening in
the conversion of health care from a
social service to a commodity, and doctors accepting that philosophy."
Despite the emphasis on commercialism and a free market economy, costs
aren't going down because health care
is not an industry, Reiman said.
"Doctors should support and enforce
ethical codes that make it clear that
they aren't businessmen," he urged.
He suggested several other things
doctors can do to remedy the restrictive
climate in American medicine. First,
every doctor should join organized
medicine, become active and vote- in
the public interest.
"Don't vote the way the longshoremen's union would, or the electrical
workers - everybody else be damned,
we're going to take care of our own,"
Reiman said. He added that while doctors should be concerned about the millions of people who are uninsured and
should push for more access to health
care, they must also help figure out
ways to pay for it.
Reiman noted that despite today's
restrictive climate, doctors still enjoy a
monopoly, much independence, the ability to self-regulate, a virtual guarantee of a
good living, and enormous power. Their
education is subsidized, research for the
new techniques doctors use was paid for
by somebody else, and hospital-based
physicians don't have to pay for the technology that they use, he said.
In exchange for all of that, Reiman
said, doctors have the obligation to
erve the public's interest. They must
accept that they have a moral contract
with society.
Physicians must help find a better
system "regardless of whether it's in our
particular economic interest or not," he

�said. "And if we do, we'll make out very
well." Society is happy to pay its experts
and heroes - doctors should have no
problem getting compensation.
Another suggestion is to let young
people experiment with group arrangements - they're not going to be lazy
because they're salaried, he said.
Fee-for-service practice will remain an
option, but it won't be the main
method of payment because it's impossibly expensive. Specialists shouldn't be
paid ten times as much as primary care
physicians. He also urged doctors to
push for no-fault insurance.
"We can afford health care if we make
the system efficient and rational," Reiman
concluded. "We doctors have to play a
role. We'll either help with the solution
e
or be judged a part of the problem."

SCRAP THE SYSTEM

T

he United States should start over
and re-create its medical system,
using the best points of the
Canadian setup, suggested Robert L.
Dickman, director of the Department of
Family Medicine at Mt. Sinai Medical
Center in Cleveland.
In Canada, the government runs the
insurance and physicians have great
clinical freedom and less paperwork.

I ~

~~

.··~·

That's what we're spending our money
on now. I think we can do better."
Medical care isn't a commodity to be
dispersed by doctors the way a baker
sells bread, Dickman said. Advertising
is fine for hamburgers, but many people
find promotions for medical care questionable. He cited the "Baby Grand"
program in which a Cleveland hospital
gave mothers $1,000 to deliver their
babies there.
He also noted that in a free market
system, McDonald's doesn't wring its
hands over the millions of people who
can't afford a Big Mac.
"If we believe that health care is a
commodity, it makes no sense to even
talk about the 30 million or 40 million
uninsured," Dickman said. "Why worry
- unless, of course, there's something
special about health care.
"If you don't think we're in the business of selling used cars, if you think
there's something noble and special
about our profession, maybe we ought to
think about the possibility of starting
over so that we don't find ourselves dealing with patients over and over again
about their insurance requirements.
"It is my belief that the only way to
solve our problems in American
medicine is to develop some kind of
unitary system that preserves the doctor-patient relationship."
Physicians should lead the way, he
said, noting that there is already a
growing organization called Physicians
for a National Health Program.
e

GRouP PRACTICE Is
THE BEST CHOICE

I.G
.

.i

Their system can't be transplanted
wholesale, Dickman said, but "I believe
we can take the best of it and make it
work for us.
"About 10 percent of our budget in
health care is to pay insurance companies so they can build those big buildings
in downtown Cleveland and Buffalo.

roup practice is, if not the best,
one of the best choices for us to
deal with complex technology
and the incredible pressure on cost of
care we face in this next decade," said
Edward J. Marine, M.D.
Marine is medical director of Health
Care Plan of Western New York, a
health maintenance organization, and
served as associate dean of the UB medical school.
Society won't add more resources for
health care; it will simply reallocate the
resources we have now, he predicted. By

the turn of the century, Marine believes,
most doctors will find themselves
involved in the managed care system.
We need managed care; that is, managed costs, Marine said. Managed care
refers to any health-care financing plan
that attempts to manage costs through
controls and influences on services and
on payments for services.
He pointed out that more than 30
million Americans have no health
insurance, and 30 million to 50 million
are underinsured.
"Everyone agrees that something
must be done," Marine said. "Everyone
also agrees that someone else should
pay for it."
The prevailing view in the medical
profession is that doctors should ignore
the cost of care, Marine said.
Instead, he suggested, the push
toward lower costs in health care
should be led by a group of well-trained
physicians dedicated to the best values
of the profession who are prepared to
apply the best principles of management to medical care.
e

DISCIPLINING DocToRs

T

he current system of handling complaints against doctors is not working,
said Peter J. Millock, general counsel,
New York State Department of Health.
It's time-consuming, it addresses too
few physicians, it wastes money, and it's
so complicated it's unintelligible to
patients and doctors.
The average case lasts 20 months,
Millock noted, and almost all physicians, including those whose licenses

�are ultimate ly suspended or revoked,
remain in practice during this time. In
1989, there were 67 such cases.
The state is now examin ing way to
streamline the system.
M illock also sees oth er sources of
change for the physician discipline system. There may be new ways to identify
substandard physicians, including recredentialing. Standards of care may become
more precise, he said, and deviations from
those standards easier to e tablish.
But a member of the audience took
exception to the idea of tightening standards of care. "What bothers me is that
standards are going to be set and your
performance is going to be monitored by
how many inches you deviate from the
standard. As an individual, that's the
most disturbing thing for me. If I wanted to be a robot, I'd be a robot."
The comments were greeted by
applause. Millock urged the speaker to
work his concerns into the changing
system.

•

MALPRACTICE CRISIS

T

he next malpractice crisis will
come in 1995, predicted Donald W.
Aaronson, M.D., an allergist who is
also an attorney.
Though he's not sure what will cause
it, Aaronson said it will be child's play
compared to the 1975 crisis, when doctors wondered whether insurance would
be available, or the 1985 crisis, when
prices skyrocketed.
Aaronson offered up another depressing tidbit: physicians in general have a
3 7 percent chance of being sued for
malpractice during their lifetime; those
in ob/gyn have a 57 percent chance.
However, there are several things
doctors can do to avoid getting sued,
said Aaronson, who is also clinical

Quality of care soon

"I don't believe the old a rt of
medicine is lost," Aaronson said. "We
care about our patients, but often we
don't know how to show it."
e

may be judged by how

Connie Oswald Stofko is editor of the

far a doctor deviates
from precise
standards. One
physician's comment:
"If I wanted to be a
robot, I'd be a robot. "
assistant professor of internal medicine
at the University of Illinois College of
Medicine and editor of Medica l
Malpractice Prevention. They include:
e Reduce patient injury. This can be
done by raising the skills of incompetent
doctors. Training programs should retain
the physicians' dignity, but bring them
up to the level they should be, he said.
e Share responsibility. Doctors
shouldn't make decisions for the
patient. Instead, they should spend
time presenting the alternatives.
Doctors should also listen to other
health professionals, such as nurses and
pharmacists.
e Keep good records. For instance,
carry paper at all times and record
phone prescriptions, he suggested.
e Improve communication. Patients
complain that doctors are concerned
only with disease, they don't listen,
they don't explain things, and they're
inaccessible.

Buffalo Phys ician and Biomedical
Scientist.

PATHOLOGY WING
DEDICATED To SANES

T

he Class of 1945 dedicated
the pathology wing in the
Cary-Farber-Sherman
Addition to the memory of the
late Samuel Sanes, M .D., a
much-admired professor, during
the Spring Clinical Day and
Reunion Weekend.
The plaque marking the wing
paid tribute to Sanes, who died
in 1978, as a physician, acting
chairman of pathology, and
community leader, as well as an
outstanding teacher. It contains
a quote from Hippocrates: "To
hold him who has taught me
this art as equal to my parents
and to live my life in partnership with him."
Those attending the ceremon y included Mildred Spencer
Sanes, his widow; Thelma
Sanes, his sister; other members
of the Sanes family; about 15
members of the Class of 1945,
and Barbara Kearney, the first
recipient of the Harold S. and
Thelma Sanes Scholarship. The
cholarship was established by
Sanes' brother and sister for students with academic promise
and financial need.
e

�WELCOME

BACK

G

etting together with old friends ts
always a highlight of the annual
Spring Clinical Day and Reunion
Weekend. A reception to welcome return,
ing alumni was held Friday, April 2 7 in UB's
Center for Tomorrow, followed the next day
by the alumni luncheon at the Marriott.
The trophy for the reunion class with the
highest percentage in attendance went to
the Class of 1960, whose chairmen were
RogerS. Dayer, M.D., and James R. Kanski,
M.D. Special recognition was given to mem,
bers of the 50,year reunion class, who wore
festive straw hats to mark the occasion.
Reunions were also held for graduates of
the Classes of 1945, 1950, 1955, 1965,
1970, 1975, 1980 and 1985.
Mark your calendars now for next year's
celebration. The reunion weekend starts
Friday, May 3, 1991.

From left, seated: Henry Severson. Morshall Ointon.
John Benny, Stanley Urban. Bernard Juveher, James
Schaus. Standing: Warren Montgomery, MaHhew O'Brien. Norbert Roberts,
Charles Mincks, Robert Hubbard, Wilham Hndebrand, Fritz Guenter, Evan
Molyneux, Albert Rekate, Harold Polanker.

1940

From left, on floor: Jacob Steinhart, Ivan Kuh~ Herbert
Joyce, Wilham Mcintosh, Robert Schopp. Seated:
Raymond Barry, Wilr10111 Loeser, Gearge Thorngate, Wilham Andaloro, Richard
Adler, Edward Fargrave, Earl Cantwell. Standing: Donald Groft, Joseph Sheedy,
George Elhs, Wayne Templer, Hnton Jacobson. Charles Wiles, Wilham Taylor,
Joseph Tannenhaus, Norman Chassin. Theodore JeweH, Albert Rosso, John
Hartman. Edward Valentine, John Ouinhvan. John Robinson. Vito Lagr10.

1945

�From left, seated: William Webster, Robert Kling,
Helen Sikorski, Richard Leberer, Bob Patterson, Leo
Manning, Joseph Mattimore. Standing: Roland Anthone, Henry Pech, John
Graf, Robert Bergner, Richard Lyons, James Curtin, James Brandl, Robert
Benninger, Vincent Scamurra, Del Dunghe, Roy Robinson, Sidney Anthone.

From left, on floor: Franklin Glockner, Francis Klocke,
Gerard Diesfeld, Thomas Guttuso. Seated: John
Lauria, Robert Malatesta, James Kanski, Roger Dayer, Naomi Leiter, Harold
Brody, Marshall Lichtman. Standing: Harry MetcaH, Daniel Rakowski, Donald
Donius, Joseph Antkowiak, Algirdas Gamziukas, Andre Lascar~ John Tuyn,
Joseph Chazan, Robert Sauer, Eugene Rivera, Harris Faigel, William
Abramson, Edwin Lamm, William Stein, Donald Hammel.

From left, seated: Robert Martin, John Peterson, John
Winter, James Nunn, Richard Carlson, Winifred
Mernan, John Baker. Standing: James Garvey, Ray Schiferle Jr., John Foley,
Albert Franco, John Kent, Larry Beahan, Robert Pittell, Frank Guzzo, Shedrick
Moore, Eugene Whitney.

From left, seated: Wilt.am Adler, Patrick Houston,
Louis Trachtman, Joseph Cardamone, George Moore,
Robert Schultz, Michael Feinberg. Second row: Harry Yerby, Barry Feinblatt,
Kenneth Kim, Steven Berman, Calvin Marantz, Ralph D'Amore, Ira Hinden,
Jerald Giller, George Strauss. Third row: Gary Jeffery, W. Scott Walls, H.
Elt.ott Larson, Wilt.am Bucher.

1950

1955

1960

1965

�From left, seoted: Wilr.om Fiden, Robert Ungerer.
Second row: Michael Uppmann, Laurence Lesser,
David Rossman, Agnes Szekeres, Roger Forden, Dennis Krauss, Robert E. Lee,
Alan Fink. Third row: Jan Novak, Ronald Zmyslinski, Donald Capley,
Sebastian (anti, JeHrey Ross, Dennis Dubois, Shafic Twal, Arthur Goshin,
Arthur Seigel. Not pictured: Donald Gabel, Neil Garroway.

From left, on floor: Mark Borer, James Twist, George
Tremiti. Second row: Theresa Stephan-Hains, Barbara
Hirsch, Ellen Tedaldi, Michael Grant, Morgoret Paroski, Harvey Arbesman,
Constance Lentz. Third row: Nancy Colligan, Maryanne Kiernan, Katherine
Jasnosz, Cynthia Parlato, Donald Switzer, Paul Trainer, Donna Oehman, Lynn
Steinbrenner, Irene Snow, James Conway, Vivian Fasula, Timothy McCullough.
Fourth row: Mark Gilbert, Thomas Masten, Robert Shalwitz, Thaddeus
Wojcik, Martin Hale, Eric Tenbrock.

From left, seated: Marguerite Dynski, Wilr.am Cohen,
Mary Lou Meyers. Second row: Jack Cukierman,
James Burdick, Henri Woodman, John Stubenbard.

From left, on floor: Sabino Torre, Jack Coyne, Kevin
Donovan, John Fudyma, Joseph Zizzi. Second row:
Shirley Galuck~ Lynda Stidham, Wendy Delaney, Thomas Cowan, Claudia
Fosket, Thomas Medige, Lucie DiMaggio, Adriana Alvarez. Third row: Michael
Lahood, Timothy Wacker, Donald Flemming, Ira Handler, Thomas Szalkowsk~
Margaret Reidy, Er.zabeth Maher, Barbara Deuell, Carl Turissini, Amy
O'Donnell, Edward Cheslow, Margaret Ubby, Donald Tingley, John Leddy.

1970

1975

1980

1985

��21

a nurse gives a vac~
cination, a lab technictan uses a Petri dish, or a patient discards a tissue.
Medical waste is created. And it's not just hospitals that generate medical
waste. Physicians' and dentists' offices make it, and so do laboratories.
Finding safe and economical ways to dispose of medical waste is a
growing concern for health care providers, research institutions, and
universities, as well as for government agencies charged with guarding
the public from exposure to potentially toxic substances.
Getting rid of such waste isn't as easy as it used to be. Most experts
agree that there's more of it, thanks to the proliferation of disposables
and single~service items such as disposable syringes, bedding, IV bot~
des, and other supplies. And the percentage of waste requiring special
handling has climbed dramatically since 1985.
The public's concern about medical waste heightened after medical~
ly related material washed up on beaches during the summers of 1987
and 1988. In addition to aesthetic concerns, fear of AIDS contributed
heavily to the public's anxiety regarding medical waste, according to a
report from the Agency for Toxic Substances and Disease Registry.
However, only a small fraction of persons infected with HIV (the AIDS
virus) are hospitalized. At any given time, more than 99 percent of all
potentially infectious HIV~infected persons are living in their homes in
the community. Thus, body fluid waste eliminated by persons with infec~
tious conditions is primarily being discarded from private homes, accord~
ing to a 1988 Oregon Department of Human Resources study.

HANDLE
It's getting harder
to throw away

By Paula Voell

CARE

�22

Only five year ago, according to 1985
Centers for Disea e Control guidelines,
less than 10 percent of total hospital
waste needed to be treated as infectious.
Today, the percentage varies, depending
on whose parameters are used.
"Three or four years ago the medical
waste given pecial handling was mainly from people in isolation," said
William D. Pike, vice president of the
Western
New
York
Hospital
Association. "They may have had an
open wound, hepatitis, pneumonia,
AIDS. Now we're handling almost all
patient care waste as medical waste."
This can account for as much as 50
to 80 percent of total hospital waste if
Centers for Disease Control universal
precautions guidelines are followed,
said Lawrence G. Doucet, a professional
engineer with Doucet and Mainka, hospital management consultants in
Peekskill, N.Y.
Categorizing the wa te ha also
become more complex. The terms
"infectious," "medical," and "hospital"
waste often are interchanged inappropriately. Hospital waste is the broadest
category and includes all solid waste.
Medical wa te describes materials such
as soiled dre sing and intravenous
tubes. Infectious waste is that portion of
medical waste that could transmit an
infectious disease. About 15 percent of
ho pita! waste is estimated to be infectious by Environmental Protection
Agency (EPA) definition.
Experts tress the importance of viewing
infectious waste in its proper perspective.
All waste, including that from homes,
may contain pathogenic organisms.
Hospitals in the eight Western New
York Counties produce about 60 tons of
solid waste daily - that includes the
potato peels from the kitchens and the
memos circulated throughout the facility.
Of that, about 16 tons is treated as infectious waste, according to William Pike.
Many of the larger hospitals and the
University incinerate their waste, but
smaller hospitals use private haulers.
David Balbierz, vice
president of BFI
Waste

Systems, says his business has steadily
increased. BFI is a private hauler with 80
medical waste disposal sites in the United
States.
Private physicians and other small
hazardous waste generators (less than
50 pounds of waste a month) have also
had to change their disposal habits.
"You can't put it in the trash any
more," said Balbierz. "For a long time
this stuff was going out to the curb, into
dumpsters or into the sewer."
Now physicians, dentist , veterinarians and others must register with the
state, fill out tracking forms and submit
annual reports. The waste has to be
packaged and marked with the generator's name and addres . As the waste
travels to its final disposal, the form
goes with it.
"The tracking system is intended to
work as a burglar alarm, alerting EPA
and state officials whenever waste has
not reached its intended destination
and leaving a paper trail that will lead
to the violators," according to discussions in the Congressional Record.

"THREE OR FOUR YEARS
AGO THE MEDICAL WASTE
GIVEN SPECIAL HANDLING
WAS MAINLY FROM PEOPLE
IN ISOLATION. NOW
WE'RE HANDLING ALMOST
ALL PATIENT CARE WASTE
AS MEDICAL WASTE."

As regulations become more tringent, skyrocketing costs of disposal take
a bigger bite out of hospital and university budgets. A study by the management and technology consulting firm of
Arthur D. Little in Cambridge, Mass.
notes that nation-wide, disposal costs
could rise from $3.7 billion in 1988 to
$10.7 billion in 1991.
To complicate the problem further,
hrinking storage capacity in landfills puts
more emphasis on incineration of wastes.
"As we approach 1992 and there is
less available (storage) capacity in the
marketplace, prices will jump considerably for a period of time as new incinerators come on line," said Melissa
Forgione, vice president of Medical
Waste Services, a Buffalo waste disposal
firm. "Then I think prices will decline,
and stabilize."
In the Buffalo area, almost all hospitals
burn waste, said William Pike of the
Western New York Hospital Association.
Before the waste is incinerated, regulations state that it must be handled
with caution. At Buffalo General
Hospital, for example, waste is placed
in red plastic bags that are transported
to a holding room on each floor in a
large cart that is eventually rolled to
the incinerator. A bracket system on
the bottom of the cart allows it to be
latched onto the incinerator.
"We have a pretty unique system,"
aid Richard Kerling, director of plant
operations at Buffalo General. "Once
the waste is in those containers, it's not
handled again."
The hospital burns six tons of solid
waste a day, everything from garbage to
paper, at an estimated co t of $240,000
for 1990, according to Kerling. Before
the incinerator was operative, it cost
the hospital 60-65 cents per pound to
have its waste hauled to a landfill in
South Carolina.
"Since the incinerator went into
operation in September 1988, to be
conservative,
- - - - - - - - - the hospital has saved
a quarter of a million dollars in
medical waste disposal costs," Kerling said.
Despite such savings, Buffalo General
and other local hospitals are facing a
crunch because the Department of
Environmental Conservation has tightened regulations on incinerator emis-

�sions. By January of 1992 even hospitals
such as Buffalo General, which has one of
the newest incinerators, won't meet the
new code without costly modifications.
"Our incinerator is just a year old,
but we'll have to upgrade it to meet the
standards," said C. J. Urlaub, Buffalo
General's vice president of
operations.
Installing a
scrubber

23

(a device
placed on an
incinerator to remove air
contaminants with water) may cost the
hospital as much as $800,000. Other
hospitals will pay from $1 million to $3
million for new incinerators, depending
on size, Pike said.
Adding to the cost is the sophistication of the new machines, which need
expensive stack monitoring and engineers to run them.
"You can't have the housekeeper
light a machine and throw the bags in,"
Pike said.
Hospital administrators are exploring
the option of joining with other facilities to cut costs.
"If 14 hospitals are spending $70 million, it would be far cheaper to have a
few larger sites," Pike said.
Some environmental officials favor
such a regional approach because it
means there are fewer incinerators
to operate and monitor, but
public outcry has been
intense against accepting
waste from outside the
community. The ot In
My Back Yard ( IMBY)
cry has become so strident,

some
wonder if it's
turned to NOPENot On Planet Earth.
Recently, Medical Waste Services
was negotiating to build an incinerator to
handle waste from several hospitals, nursing homes and physicians' offices in the
southern part of the state. The project
was defeated because of citizen outcry.
Medical Waste Services picks up
10,000 pounds of waste each week from
small generators as well as from Our
Lady of Victory and Columbus
Hospitals, facilities which do not have
their own incinerators.
"We provide the packing, permitted
hauler and insurance," said Forgione,
the company's vice president.
Boxes for waste storage and disposal
provided to its clients by Medical
Waste Services come in three sizes and
include a three-millimeter liner. A box
18 by 18 by 24 inches that holds 30
pounds costs $27 for disposal. On average, private physicians produce one
box of infectious

waste every two weeks, according to
Forgione.
BFI workers who pick up medical
waste are given extensive training
in how to handle the waste and what
protective clothing to wear, said
Balbierz.
"Actually, the people who pick up
regular (curbside) trash are less protected because they don't know what's in
it," he said.
Waste haulers point out that ordinary
garbage from private homes can include
needles (it is estimated that one billion
needles are discarded by diabetics annually), as well as waste from infectious
di eases such a hepatitis.
Misconceptions about treatment of
hospital waste abound, despite increasing amounts of attention to the problem, Pike said.
"I think people assume that hepatitis
will be coming out of stacks and that hundreds of trucks will come to a property and
that's just not true," he said.

�HOW UB HANDLES MEDIC
24

The University produces about
35,000 pounds of medical waste
annually from its 60 laboratories,
mainly utensils containing culture
media from labs in the schools of
medicine, dentistry, and nursing.
"The state regulation in relation
to the University seem very stringent," said Robert E. Hunt, director
of Environmental Health and Safety
at UB, which has an incinerator on
the South Campus. "For a long time
the state regulations said that once
infectious waste was autoclaved
(sterilized with steam) it could be
treated as trash and go to a sanitary
landfill. That was no problem for
us except for a few labs who had to
find a way to autoclave.
"But recently a sentence was
added to the regulations to
require that all regulated medical waste has to be made nonrecognizable, so it has to be
incinerated or ground up. We are
using incineration but it's causing considerable problems because a big share
in poundage is plastic - flask tubes,
pipettes and Petri dishes. That's

extremely
difficult to incinerate efficiently, to
bum up at high temperatures efficiently enough so you don't get a lot of byproducts in the air."
To cut down on the amount that has
to be incinerated at UB, labs are advised
to put all clean glass and plas:~m~
tics in special containers
'glass,' Hunt says.
These are collected

puncture-

Balbierz
estimates
t h at only two
to five percen t
of waste
is
pat h o l ogica l
waste, but con cedes t h at t h e
public has a different perspective.
"Th ey h ave t h e
misconception that o ur
AU11JM

1990

resistant cartons to be
disposed of in permitted landfills.
Hunt
doesn't
think the
health industry will revert to
reusable supplies.
"I've thought
about it, but there's
just so much expense
involved with the handling, cleaning and storage of glassware that maybe
a lot of researchers would find
it impossible to continue."
William Pike, vice president of
the Western New York Hospital
Association, agrees it's unlikely that
hospitals will go back to reusables.
"The reason we use disposables is
sterility. If there was a fault in the autoclave, would you want a needle reused?
"And I think that there would be a
concern for infection with blood
products if we switched from the use
of throwaway plastic bags."
Pike said that hospitals are more
likely to look for ways to cut down
on disposable items and encourage
recycling in areas other than
patient care.
"There are other things hospitals
could do in such things as packaging
for food - eliminating the use of
Styrofoam, for example," he said.

trucks are filled with body parts, when
actually most of our waste is rubber
gloves, disposable gowns, the paper
used on examinating tables, masks and
tongue depressors."
Before all the dust settles on how best
to dispose of hazardous waste, Melissa
Forgione says, people will have to
become better informed.

Paula Voell is a reporter for the
Buffalo News.

BUFFALO PHYSICIAN AND BIOM EDICAL SCIENTIST

•

�... ----------------------------------/f

0

25

The Body Snatchers
Elwood lecturer tells how grave robbing and
murder charges ensnared a famous anatomist
BY JEFFREY TREBB

A

•

19th century anatomist whose
illustrious career was destroyed by
charges of grave robbing was the
subject of the Charles L. Elwood
Memorial Lecture in March.
The lecture was delivered by Sherwin
B. Nuland, associate professor of surgery
at Yale School of Medicine, whose visit
to Buffalo was sponsored by the Alpha
Omega Alpha national medical honorary society.
According to Nuland, it was only stubborn self-assurance that allowed the
Scottish anatomist Robert Knox to become
implicated in a series of murders committed
to furnish specimens for dissection.
In his lecture, "Goodness Tainted:
Robert Knox and the Anatomy
Murders," Nuland told his audience:
"Robert Knox (1791-1862) was a paladin destroyed by his own code of
honor, for although his drive and talent
seemed to promise a glorious academic
future, his destiny became his downfall
when he was scapegoated for a series of
crimes instigated by the medical science of his time.
"By confusing egotism with purity of
conscience, by believing compromise
signifies cowardice and by equating
pragmatism with weakness, Knox sacrificed great achievement on the altar of
vanity," Nuland said.
The actual "scoundrels" were two
navy workers on the Union Canal
between Edinburgh and Glasgow,
William Hare and William Burke.
Nuland called both "familiar with all
BUFFALO PHYSICIAN A 0 BIOMEDICAL SCIENTIST

Detail from "The Anatomy Lesson of Dr. Tulp," Rembrandt, 1632

In 1828, corpses of
murder victims were
sold for about seven
British pounds apiece.

the woe, wretchedness, guilt and pollution" life contains and said they
embarked on a spree of killings shortly
after Hare filled an already-dead neighbor's coffin with tanner's bark and sold
the man's corpse to the medical college,
becoming quite impressed with the simplicity of the deed.
All colleges in Great Britain early in
the 19th century were facing an
increased need for corpses owing to the
growth of surgery with its new emphasis
on detail, and also to the higher standards of care legislated by government.
AUTUMN 1990

�...
If

-----------------------------------------

0

26

And procuring bodies for dissection,
Nuland pointed out, usually meant
resorting to illegal measures of some
variety since the two legal sources, the
bodies of executed criminals and those
of the unclaimed dead in hospitals,
never approached the demand.
"The need was insatiable. You just
couldn't teach without corpses," he said.
Grave robbers, or "resurrectionists,"
supplied what they could, but eventually
graves became clo ely watched over by
relatives of the deceased, said Nuland.
So Burke and Hare turned to murder.
Burke even gave his name to a style
of suffocation: To "burke" someone
meant strangling him while sitting atop
his chest. In all, Burke and Hare killed
about 30 persons in 1828, netting about
seven British pounds per body.
The pair brought suspicion upon
themselves after murdering several
well-known prostitutes. An elderly
woman they brought home from a tea
shop, plied with gin, and killed after an
evening of dancing and singing, was
their last victim. Unfortunately for
Knox, the body, purchased by assistants,
was found in his dissection cell.
Nuland described Knox as a "man of
solitary self-regard, endowed with an
air of authority, possessed of charm, cultivating distinctiveness." He had studied in Paris with Georges Cuvier, the
French zoologist and statesman, who
established the sciences of comparative
anatomy and paleontology. Shortly
after returning to Edinburgh in 1822,
Knox established a museum of comparative anatomy at the Royal College of
Surgeons in Edinburgh.
"Knox's enviable command of language and his showman hip drew students in huge numbers; not only
anatomists but artists and divinity students. He was a tourist attraction for

AUTUM

1990

cultivated travelers and at the threshold of an illustrious career," aid
Nuland. "The greatest anatomy teacher
of his day, he was also skilled in paleontology and comparative morphology."
But because the body was found in
his room, Knox "faced all the frustration built up by a century of grave robbing. He was scolded for every sin ever
committed in every aspect of medical
science," said Nuland. The press derided him, he was burned in effigy, he was
forced to walk through creaming
crowds to give his lectures. A folk song
closed with "Burke's the butcher, Hare's
the thief, Knox is the boy who buys the
beef." Few colleagues came to his
defense. Even his admiring students left
his side.
This despite the fact that he was
acquitted in court late in 1828, according
to Nuland. (Burke was found guilty on
Hare's testimony and hanged before
20,000 onlookers. His dead body was sent

to the anatomy school for dissection.)
Nuland claimed the anatomist was
brought low by pride and vanity: "Knox
cast ridicule on the opinions and men
of the time and flaunted his talents,
inviting bombardment. He believed it
beneath his dignity to respond to the
charges, and the reverberations followed him the rest of his life."
Knox lost his job as curator of the
anatomy museum and was forced to
resign from the University of
Edinburgh. He rambled about the country barely surviving by lecturing on
anatomy and fishing and writing for
magazines in London. He was expelled
from the Royal Society of Edinburgh for
non-payment of dues. This career as a
perennial free-lancer was relieved by
only one respectable position as a fellow of the Ethnological Society of
London. In 1862, long after his wife
and all his children were dead, Knox
e
died of a stroke.

BUFFALO PHYSICIAN AND BIOMEDICAL

IE TIST

�27

MILGROM OUTLINES
WoRK ON
ANTIANTIBODIES

A

t one time, it was believed that
the body's immune system could
not make antibodies that would
be destructive to the host's own tissue.
But Felix Milgrom, a distinguished professor of microbiology at UB, helped to
prove that theory wrong through his
work with antiantibodies.
Milgrom delivered the 20th Annual
Ernest Witebsky Memorial Lecture in
May at the Center for Tomorrow on
UB's North (Amherst) Campus.
"The theme of antiantibodies is
something that I have been pursuing for
44 years," Milgrom said, outlining his
research career. "It is something that I
have been pursuing from the very
beginning of my research."
In outlining his research, Milgrom

Felix MUgrom, M.D.
BUFFALO PHYSICIAN A D BIOMEDICAL SCIENTIST

issued a caveat to his capacity audience.
"The lecture," he said, "was not
designed to be a comprehensive treatment of this topic." Milgrom noted
that the audience would require a graduate seminar in advanced microbiology
if they wanted to really understand
what the topic encompassed.
Milgrom worked at UB from the
1950s through the mid-1960s with the
late Ernest Witebsky, whom Milgrom
called "the world's most brilliant immunologist." Their work made great strides
toward disproving the old theory about
autoimmunity.
Another "first" for Milgrom was
demonstrating in the laboratory that
some forms of kidney graft rejection are
caused by antibodies present in the circulation of presensitized recipients.
That was an important piece of information in 1968 when the field of
human organ transplantation was new.
His research also clarified the structure of rheumatoid factor, an antibody.

Milgrom noted that over the years,
UB's Department of Microbiology has
attracted hundreds of students. About
40 or 50 now head departments or
institutes focusing on immunology in
the U.S. and abroad.
A native of Poland, Milgrom was chair
of the Department of Microbiology at
Silesian University School of Medicine
in Zabrze, Poland, and a professor and
acting chair at the University of Wroclaw
in Poland, before coming to UB.
Milgram has authored about 600 professional articles and has served as editor
for several books. He was awarded the
Paul Ehrlich Prize in 1986 in recognition
of his distinguished service in the fields
of immunology and chemotherapy.
After Milgram's lecture, the Ernest
Witebsky Memorial Awards for proficiency in microbiology were given to
Seth Dewey, a medical student; Jennifer
Kuracina, a dental student, and
Haiping Mei and Ai Shih, both graduate students in microbiology.
e
AUTUMN 1990

�28

LISTEN WITH HEART,
ABRAM TELLS GRADS

A

very personal message came with
this year's commencement speech
to the School of Medicine and
Biomedical Sciences. The 145 medical
students, 25 doctoral tudents and their
familie and friends heard diplomat
Morris Abram advise graduates to
"shorten your stethoscopes to hear what
patients are saying and feeling."
Abram, the U.S. representative to
the European Office of the United
ations and Other International
Organizations, Geneva, and former
Diplomat Morris Abram addresses graduates.
president of Brandeis University, keyed
his address to the relationship between
doctor and patient. But it was more years, had shortened the listening tube
than a theoretical overview from a sani- of his stethoscope.
tized ivory tower. Abram shared his per"One day a young resident came up
anal experiences with the graduates, to thi wise old man and said, 'Doc,
talking about hi own bout with why do you use such a short stetholeukemia that lasted five years.
scope? Did you buy it that way?' He
"The relationship between doctor and said, ' o son, I just had to keep cutting
patient is one of extraordinary psycho- it off.' He was a man who paid very litlogical and emotional interplay," Abram tle attention to technology and a great
said, reflecting on the sometimes-anx- deal of attention to what he was hearious encounters with hi own team of ing," Abram said.
physicians during chemotherapy.
In looking at patients this way,
Anguish, frustration, and reverence are Abram said, physicians will be able to
all felt by the patient toward his physi- determine how much information they
cian, he said, pointing out that, in time, can give the patient, whether or not
especially with diagnosis of a disease that the patient has the "instinct and will to
can be fatal, patients begin to scrutinize fight to survive," and if the patient is
the doctor's every word and nuance.
realistically facing the severity of his ill"I remember the anxiety of sitting by ness, he added.
the phone waiting to hear the results of
The historical and technological
my bone marrow from my hematologi t. changes that have taken place in
I would sit by the phone and think, medicine since 1846, when the UB
'Why hasn't he called? What's wrong?' medical school was established, have
Finally he called and he said, 'The bone affected the doctor-patient relationmarrow looks good.' I said, 'What does ship, Abram said.
that mean? Does it mean it doe n't look
The first hundred years were marked
great?'" Abram added with emotion.
by a small arsenal of treatments, and
The speaker recounted the story of a bedside manner was sometimes the best
learned physician, who, through the medicine, Abram said. Technology has

AUTUMN 1990

moved ahead in leaps and bounds, but
to orne extent it has caused the physician to focus on body parts rather than
look at the whole human being.
Abram referred to some of the frustrations today's physicians face - the
increasing risk of malpractice, bureaucratic red tape, immense amounts of information to be absorbed - all of which result
in le time for patient interaction.
There is precious little time for
"rumination about the symbiosis
between the healer and healed" in the
cour e of medical training today and
among practicing doctors, Abram said.
But he urged the new physicians to listen and study their patients, not just
from a biomedical standpoint, but also
from an emotional one.
Abram told the audience that during
hi bout with leukemia, he was under
the care of James E Holland, M.D., former chief of medicine at Roswell Park
Memorial Institute and former director
of Roswell Park's Cancer Clinical
Research Center. Holland, who wa also
research professor of medicine at UB, is
now at Mt. Sinai School of Medicine
and Hospital in New York City where

BUFFALO PHYSICIA

AND BIOMEDICAL SCIENTIST

�29

he is professor of medicine, chief of the
Division of Medical Oncology, and
director of the Cancer Center.
A lawyer by training, Abram is a man
of many accomplishmen ts, said John
Naughton, M.D., vice president for
clinical affairs and dean of the UB medical school, who introduced the speaker. Abram is a Rhodes scholar, a former
president of the United Jewish Appeal,
and has served on state, local, and
in ternational commissions including a
presidential-appo in ted committee
examining medical ethics.
This year's commencement was highlighted by the graduation of the medical school's first M.D./Ph.D candidate,
Edwin Heidelberger. The first graduates
of UB's Early Assurance Prog ram,
which allows qualified students to apply
early, also crossed the threshold from
e
student to resident.

- By David Himmelgreen

Richard Condit, Ph.D., associate professor of
biochemistry, listens thoughtfully.
Dennis Nadler, M.D., associate dean, witnesses the signing of the Book of Physicians
by Constantine Petrochko.

BUFFALO PHYSICIA AND BIOMEDICAL SCIENTIST

AUTUMN 1990

�30

a
Martha Pierre, left, shares her exciting news with Shiau-Wen Pien and Jase Rivera.

89°/o GET ToP CHOICE
AT 'BEST' MATCH DAY

T

hey streamed through the doors of
Butler Auditorium like the ancient
Hebrews making their way through
the parted waters of the Red Sea.
Some had bottles of champagne, others had babies and spouses. They were
all buddies who just completed four
years of training in quest of becoming
fine physicians. And now they were
about to embark on another journey.

March 21 was Match Day, the annual
event held at medical schools across the
country where fourth-year students find
out where they'll spend their residencies.
The UB students had to wait through
the announcements - yearbooks, graduation speaker, and in tructions on how
to sign the alumni scroll - before they
would get those coveted envelopes
telling them where they would be going.
AUTUM

1990

Then they waited some more as
Dennis Nadler, associate dean for curricular and academic affairs for the medical school and director of the office of
medical education, reported on the
statistics. The tension was mounting.
There were 141 students who participared in this year's match, said Nadler.
It was the best year since 1979, when
Nadler first began keeping records. This
year 67 percent of the students got their
first choice, up 2 percent from last year,
said Nadler. And another record was
broken with a whopping 89 percent of
the students getting one of their top
three choices.
(Five students didn't enter the
match: one was a military match, one
was a student in the Medical Scientist
Training Program who began a residency in January, one chose graduate study
in physiology, one accepted a part-time
position in Vermont, and one got a
position after the match.)
The applause thundered through the

auditorium as the students realized just
how good a class they were.
UB students are going to some of the
best and most highly competitive residency programs in the country. Nadler
exclaimed that UB finally cracked the
prestigious residency program at
Massachusetts General in Boston. He
added that UB is also sending students
to other top-notch programs such as
Duke and Johns Hopkins.
But Nadler had to make the students
squirm just a little more. As he
clenched the envelopes that would tell
them of their fate, he said with a grin,
"I made an effort to randomize them."
The students booed as if they just saw a
Bills player drop a pass.
Then, one-by-one, they came up,
some with trepidation, but many with
beaming smiles splashed across their
faces, to get the sacred envelopes.
Cheers broke out and champagne
corks flew through the air. There were
plenty of hugs, smiles, and celebrations.
"I got my first choice - Syracuse,"
said Anthony Navone, a medical student, who added that "after five years
and $75,000 it was all worth it."
Heidi DeBlock, another student, who
brought along her husband Scott and
daughter Alexandra, was ecstatic that she
was going to Rochester, her first choice.
Ralph Augustini, who's a glutton for
cold weather, will be spending the next
several years at the University of
Michigan. He was full of good cheer
and drenched with champagne and
kisses from well-wishers.
"I just want to congratulate all of my
classmates," he said.
Nadler summed it up: "We have a
strong class. We did well, exceptionally
w~ll. It was an impressive result especially because the competition is getting tighter every year."
e

- By David Himmelgreen
BUFFALO PHYSICIA

A D BIOMEDICAL SCIE TIST

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31

Dr. Herz Goes to Washington
UB psychiatry chair tightens up
mental health grants
BY LOIS BAKER

A

stint as a senior science advisor at
the National Institute of Mental
Health (NIMH) has given a UB
professor new perspective on the workings of Washington bureaucracy.
Marvin I. Herz, M.D., professor and
chair of the Department of Psychiatry
at UB's School of Medicine and
Biomedical Sciences, spent September
through December at the NIMH as
advisor to the director, Lewis Judd.
He found the work in Washington
interesting, but prefers to be closer to
the front lines.
"I got a close look at how the federal
bureaucracy works," said Herz, "and I
enjoyed meeting people and exchanging ideas. But it's much more rewarding
to be in a setting where you can actually work with patients, actively direct
their care, and do the research.
"These people administer programs
that other people do. They don't work
with patients, students or faculty. They
are far away from where the action is."
Herz was invited to NIMH headquarters
in Washington, D.C., for work with the
Division of Education and Service Systems
Liaison because of his expertise. He is one
of the few physicians in the United States
who has devoted his career to researching
new treatments for schizophrenia and
other serious mental illnesses.
BUFFALO PHYSIC IA

AND BIOMEDICAL SCIE TIST

"I got a close look at

how the federal
bureaucracy works ,
but it's much more
rewarding to be in a
setting where you
can actually work
with patients. "
Herz's mission was to bring a more
scientific orientation to the division's
projects.The largest task of this division
is to fund clinical trials that try to find
more effective ways to treat seriously
mentally ill children and adults. The
funding is channeled through state
Departments of Mental Health.
"The problem in the past with these
demonstration projects has been that
they were never scientific enough to be

reported in the literature so they could
be replicated," said Herz.
One grant that Herz reviewed was an
extension of some of his own previous
work. It proposed to study schizophrenic
patients and the benefits of intervening in
their treatment at the first signs of relapse.
Herz said that traditionally, professionals
treating schizophrenics tum to crisis counseling for the family and an increase in
medication for the patient only after the
patient has suffered a full relapse which
usually sends the patient to the hospital.
"When early signs of relapse appear,
several days or a week usually pass before
the episode progresses to full relapse,"
Herz said. "By intervening early we
expect a decrease in hospitalization as
well as less family burden and improved
functioning of the patient."
Herz said, "My job was to tighten up
the demonstration grants - define the
population, give a clear description of the
grant's intention, make sure they were
using randomized control studies, if possible, and valid and reliable instruments to
register change.
"In the past they couldn't describe
what was actually done because the
results weren't clear."
He also advised the demonstration
project staff on ways to treat seriously
mentally ill patients, and helped sharpAUTUMN 1990

�0

v

32

PoRTIN Is PRESIDENT
OF MEDICAL ALUMNI

B

ertram A. Portin, M.D. '53, has been
elected to a one-year term as president
of the UB Medical Alumni Association.
edra J. Harrison, M.D. '77, was elected vice president, and Donald P. Copley,
M.D. '70, was elected treasurer.
Portin, a colon and rectal surgeon, is a
UB clinical professor of surgery and chairman of the division of colon and rectal
surgery in the Department of Surgery.
Certified by the American Board of
Surgery and American Board of Colon
and Rectal Surgery, Portin is an attending surgeon and chair of the Division of
Colon and Rectal Surgery at Buffalo
General Hospital.
Harrison, a general surgeon, is a clinical instructor of surgery at UB.
Copley is a clinical professor of medicine in UB's Department of Cardiology. e
Robert M. Barone, M.D., a general surgeon, has been elected president of
Millard Fillmore Hospitals' voting medi~ cal staff for 1990-92. Barone is a clinical
~ assistant professor of surgery at UB. e

§

Q Sister Angela Bontempo, pre ident of

Marvin I. Herz, M.D.

en the focus of training programs for
psychiatrist , social workers and other
mental health professionals.
He continue to serve a a consultant
to the institute.
Herz developed an interest in treating serious mental illness during his
directorship of the inpatient unit of
New York City's Montefiore Hospital
from 1961-1963. He later spent 12
years as director of community p ychiatric programs at Columbia College of
Physicians and Surgeon and New York

::W.iiiiiiliiiiiiiiiiiiliiiiiiiiiiliiol

State Psychiatric Institute.
In addition to his UB position, Herz
currently i director of psychiatry at the
Erie County Medical Center and Buffalo
General Hospital, as well as consultant
at the VA Medical Center. He was elected recently to the Board of Regents of
the American College of Psychiatry.
Herz's research has earned accolades
in the past. In 1988 he received the
American Psychiatric Association's
Psychiatric Institute of America Foundation Award for Hospital Research.
e

~ Sisters Hospital, has been appointed to
the state's Public Health Council. The
14-member council advises the State
Commissioner of Health and considers
matters relating to the preservation and
improvement of public health.
e
Gregory Branch was one of 10 medical
students nation -wide to receive a
Metropolitan Life Foundation Award
for academic excellence in medicine.
The honor includes a 2,500 tipend.
He· is now a fourth-year student.
e
Kandala Chary, M.D., has been elected

pre ident of the Sisters Hospital medi-

AUTUMN 1990
BUFFALO PHYSICIA

AND BIOMEDICAL SCIENTIST

�0

'

33

cal staff. Chary is a clinical instructor in
medicine and otolaryngology at UB and
has served as president of the Asian
American Physicians Association.
e

1918fLU EPIDEMICGRAD WAS THERE

Thomas J. Dougherty, Ph.D., director of
radiation biology at Roswell Park
Cancer Institute and associate professor
of pathology and radiobiology at UB,
received the Gustavus John Esselsen
Award for Chemistry in the Public
Interest. Dougherty was recognized for
his research leading to the development
of photodynamic therapy (PDT), a
potential new approach to the treatment of certain types of cancer. The
award was presented at the annual
meeting of the American Chemical
Society in April.
e
Leonard G. Feld, M.D., Ph.D, associate
professor of pediatrics and physiology at
UB, has been elected to the American
Physiological Society. Feld is also chief
of the Division of Nephrology at
Children's Hospital and director of the
Children's Kidney Center of Buffalo,
which is located at the hospital.
He recently received a $96,600 grant
from the Juvenile Diabetes Foundation
International to study the long-term
effect of the drug aminoguanidine,
which will be used to prevent glucose
from damaging the membranes within
the kidney.
e
John Naughton, M.D., dean of the medical school and vice president for clinical affairs at UB, has been named
Physician of the Year in Academic
Medicine by the alumni association of
the University of Oklahoma College of
Medicine, where he received his medical degree in 1958. aughton was cited
for "outstanding contributions and
leadership in furthering scholarship,
administration and research."
e

BUFFALO PHYSICIA

AND BIOMEDICAL SCIE TIST

John D. Pigott, M.D.

John D. Pigott, M.D., a specialist in congenital cardiac surgery, has been
appointed chief of the Division of
Cardiovascular Surgery at Children's
Hospital and associate professor of
surgery at UB. With this appointment,
Buffalo is now offering state-of-the-art
heart therapy for children that is not
available elsewhere in the state. Pigott
had been a cardiac surgeon at the
Children's Hospital of Philadelphia.

e

James J. Reidy, M.D., has been named
director and chief-of-service for the
cornea service in the Department of
Ophthalmology at UB.
e
John P. Visco, M.D., a cardiologist at
Buffalo General Hospital, has been
elected president of the hospital's medical staff for 1990. Visco is also a clinical
assistant professor of medicine at UB. e

Gentlemen:
Thank you, sincerely, for publishing the
article, "Flu," written by Deborah Brunch
Bucki, R.N., M.S. It sure brought back
many memories of my early life in
Buffalo. 'I was there,' so to speak.
In the fall of 1918, I was a member of
the senior class, South Park High School.
I became ill at school and was excused. I
walked home a distance of one-half mile.
On arrival home, my mother took my
temperature - it was 104. It was diagnosed as influenza and I recovered after
one week- no complications.
I graduated from the University of
Buffalo Medical School in 1925
interned at the Buffalo City Hospitai
and remained there 20 years
(1925-194 5), except for a two-year
period in the mid-1930s when I attended the Johns Hopkins School of Public
Health where I was granted the degree
of Doctor of Public Health (D.P.H.).
I succeeded Dr. Walter S. Goodale on
his death in 1941 as superintendent of
the City Hospital and professor and
head of the Department of Preventive
Medicine at the University of Buffalo.
All of the doctors mentioned in the
article: Goodale, Fronczak, Gram, Cott,
Meyer, Sherman and Jacobson, were
friends of mine - great men, all of them.
I departed from Buffalo in 1945 and
for the next 21 years served as superintendent of the New York State Masonic
Home and Hospital, in Utica, N.Y.
I retired in 1966 and since then have
lived in "God's Country," the foothills
of the Adirondacks at Woodgate, N.Y.
I was 89 years of age in August and
enjoy good health.

William T. Clark, M.D., D.P.H.

AUTUMN 1990

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34

most advanced in the world. It features a
unique environmental chamber which
simulates the equivalent of depths of
5,600 feet beneath the sea or 100,000
feet in altitude. It also includes a
centrifuge capable of simulating up to
10 "Gs" or gravities and a submersion
basin which provides underwater observation of subjects against specified rates
of currents.

HERMANN RAHN DIES;
PHYSIOLOGY PIONEER
LooKED To SKIES, SEAS

H

ermann Rahn, Ph.D., whose pioneering research in environmental physiology helped provide the
foundation for today's aerospace and
undersea medicine, died June 23 after a
brief illness. He was 77.

Leon Farhi, M.D., chairman of UB's
Department of Physiology, has noted
that while environmental physiology
was on the books for a long time, it
really blossomed in the early 1940s
when Hermann Rahn made his contributions to the field.

Rahn, distinguished professor of
physiology at UB, served as chairman of
the Department of Physiology at the
medical school from 1956 to 1973.
A native of Michigan, Rahn received
an A.B. degree from Cornell in 1933
and a Ph.D. degree from the University
of Rochester five years later.
Joining the UR faculty after teaching
briefly at the University of Wyoming
and spending a year as a fellow at
Harvard, Rahn, with his colleagues,
conducted research which benefited
Allied pilots and soldiers in World War
II. The Rochester team assisted the
U.S. Army in determining the amount
of water and other essentials needed for
desert survival prior to the landing of
U.S. troops in North Africa.
Later, the researchers used a converted brewery tank as a primitive altitude
chamber to study hypoxia, which
caused pilots to lose consciousness at
high altitudes.
Although he officially retired in
1985, Rahn continued to put in six-day
workweeks in his lab until shortly
before his death. His research in comparative respiratory physiology involved
work with eggs ranging from those of
the ostrich to the hummingbird. During
15 years of research in this field, he
served as a consultant to the poultry
indu try and to those interested in the
field he founded, incubation physiology.

AUTUM

1990

Hermann Rahn, Ph.D.

Although Rahn's scientific interests
spanned a range of subjects within biology, his primary interests were comparative physiology and pulmonary physiology, in which man or animals adapt and
interact with different environments.
Basic knowledge he provided in this
area advanced the understanding of
lung dysfunction in patients with pulmonary diseases. For this work, he
received the American Lung Association's prestigious Trudeau Medal.
A device he invented led to development of the self-guided cardiac catheter
used today in diagnosis of cardiovascular problems.
Rahn's vision, enthusiasm and determination helped build UB's Department of Physiology into an international center for environmental physiology.
The Hermann Rahn Laboratory,
housed in the UB Center for Research
in Special Environments, is one of the

Rahn's research earned him many
honors, including the U.S. Air Force's
Meritorious Civilian Service Award,
the highest given a civilian; election to
the prestigious National Academy of
Sciences and the American Academy
of Arts and Sciences; and honorary
degrees from the Universities of
Rochester, Bern (Switzerland), Paris,
and Seoul (Korea). He was the first
recipient of the Under-Sea Medical
Society's top honor, the Benke Award.
During his career, Rahn had been a
visiting professor at several institutes
abroad and was a president of the
American Physiological Society and
vice president of the International
Union of Physiological Sciences. He
was the author of more than 200 scientific articles and four major texts.
A dedicated teacher as well as a
researcher, Rahn inspired many graduate students and fellows who studied
with him at UB to follow successful
careers in physiology.
A Hermann Rahn Memorial Fund has
been established and contributions may
be sent to the Department of Physiology,
124 Sherman Hall, University at
Buffalo, Buffalo, N.Y. 14214.
e

BUFFALO PHYSICIAN A 0 BIOMEDICAL SCIENTIST

�35

1940.,
Stanley L. Olinick '40 :l&gt;
writes that his busy schedule
includes a half-time practice,
teaching, writing, friends, tennis
and music.
Anthony M. Aquilina '44 :l&gt;
of Amherst, N .Y., was elected
president of the Baccilli
Medical Club for 1990.
William D. Loeser '45 :l&gt; is
now retired from private practice. "! work part time for a
nursing home ... love it!"
Albert J. Rosso '45 :l&gt; writes,
"My wife of 41 years and I have
eight wonderful children and 16
fine grandchildren."
David J. Shaheen '45 )&gt; retired
in 1986 and is now living in
Titusville, Fla.
Jacob M. Steinhart '45 :l&gt; of
Clarence, N.Y., writes, "Still enjoying the private practice of pediatrics, but in a six-man group!"
Gilbert B. Tybring '45 :l&gt; who
has been retired for five years,
edits the Wisconsin Psychiatrist.
Vernon G. mith '48 :l&gt; of
Orchard Park, N.Y., retired from
his private practice in pathology
in 1987 due to a severe fracture
of the right femur.
Max A . Schneider '49 :l&gt; who
is known internationally for his
work in the field of addiction
medicine, was recently appointed an associate clinical professor
of psychiatry at the University
of California College of
Medicine at Irvine.
Henry A. Thiede '49 :l&gt;
appears in the videotape "The
History of Certification in

Emergency Medicine" produced
by the American Board of
Emergency Medicine. This tape
was made to celebrate the recognition of emergency medicine as
a specialty and to commemorate
the individuals involved in the
history of certification.

Robert Benninger '50 :l&gt; is
now retired and enjoying life in
Cape Coral, Fla.
George P. Bisgeier '50 :l&gt; former
medical director of New Jersey
Bell, is semi-retired and doing
part-time occupational medicine.
Karl L. Manders '50 :l&gt; of
Indianapolis, Ind., recently published "Indications for Surgery in
Back Pain" in Seminars in
Neurology. In addition to his
practice in neurosurgery, he continues as medical director of the
Community Hospital Rehabilitation Center for Pain. Dr.
Manders is currently president of
the Midwest Pain Society.
Ernest H. Meese '54 :l&gt; was
elected president of the board of
trustees of the American
Cancer Society Ohio Division.
He has been a volunteer with
the Cancer Society for 26 years.
Dr. Meese has a private practice
of thoracic and cardiovascular
surgery in Cincinnati and is an
assistant clinical professor of
surgery at the University of
Cincinnati Medical Center.
Milton Alter '55 :l&gt; left his
position as chairman of neurology at Temple University and is
now professor of neurology and
director of the residency training program at the Medical
College of Pennsylvania. He
holds an NIH grant to study the
epidemiology of strokes and was

BUFFALO PHYSICIAN AND BIOMEDICAL SCIENTIST

recently awarded a supplemental grant to study risk factors for
recurrent strokes.
George L. Mye Jr. '55 :l&gt; of
Yelm, Wash., retired in July
from general surgery and a partnership in a Southern
California Permanente Medical
Group.
David L. Palmerton '55 :l&gt; of
Clarence, N.Y., writes, "! retired
six years ago, but I am into
starting up home health care
agencies in Florida and
Virginia."
Jerome P. Kassirer '57 :l&gt; the
Sara Murray Jordan Professor of
Medicine at Tufts University
School of Medicine in Boston,
has been elected to the Board of
Regents of the American College
of Physicians. He began a threeyear term in April.
Daniel C. Kozera '59 :l&gt; a clinical assistant professor at UB, is acting chief of ob/gyn at Mercy
Hospital and a consultant for
ob/gyn to the Erie County and
New York State Health
Departments.

1960.\
Franklin Glockner '60 :l&gt; is
now working full time in the
Division of Orthopaedic
Surgery at Albany Medical
College and is chief of
orthopaedic surgery at the VA
Hospital.
Edwin R . Lamm '60 )&gt;
was elected president of the
medical staff at Lakeland
Regional Medical Center in
Lakeland, Fla.
Eugene T. Partridge '60 :l&gt; of
Buffalo has 12 grandchildren
and is expecting more.

Joseph A. Chazan '60 :l&gt; director of the Division of Renal
Diseases at Rhode Island
Hospital and associate clinical
professor of medicine at Brown
University, took office in April
as governor for the Rhode
Island chapter of the American
College of Physicians.
Jeffrey E. Lindenbaum '66 :l&gt;
has been appointed clinical
director of a new joint venture
adolescent medicine program
with Children's Hospital and
Medical Center in Seattle, Wash.
Stephen E. Langer '67 )&gt; of
Berkeley, Calif., is medical editor
of the National Examiner. His
column reaches 6 million people
per week. Dr. Langer is currently
president of the American
Nutritional Medical Association.
John E. Shields '68 :l&gt; is a consultant at the Seafield Alcohol
Treatment Center in Westhampton Beach, N.Y.

1970s
Jan Novak '70 :l&gt; has been reelected president of the medicaldental staff of the Erie County
Medical Center. He is an attending in medicine and heads the
gastroenterology unit of the hospital.
Kenneth Solomon '71 :l&gt; associate professor in the Division of
Geriatric Psychiatry at St. Louis
University School of Medicine,
presented at the Department of
Psychiatry Grand Rounds at the
Erie County Medical Center
and the VA Medical Center in
Buffalo April 20.
Patricia K. Duffner '72 :l&gt; has
been elected president of
Children's Hospital medical
staff, the first woman elected to
AUTUMN 1990

�36

the post. A professor of neurology and associate professor of
pediatrics at UB, she has coauthored a book with Michael
Cohen, M.D., on brain tumors
in children.

past 11/z years she has also been
involved in public sector work.
Dr. Turner has 2 sons, 5 1/z years
and 2 years. Her husband, Alan,
is a member of the Dallas
Symphony.

Arthur W. Mruczek '73 &gt; has
been appointed director of the
contact lens service at the Erie
County Medical Center. The service will include therapeutic as
well as co metic contact len es.

Mark Chung '82 &gt; writes, "I
am a practicing pulmonologist at
Los Alamitos, Calif., having
graduated from Harbor-UCLA
training program, and have been
appointed lieutenant commander
with the U. . Naval Reserve."

Nancy H . Nielsen '76 &gt; has
been named to the State
University of New York Board of
Trustees. A clinical assistant professor of medicine at UB,
Niel en practices medicine with
the Buffalo Medical Group. She
is a medical consultant to the
bacteriology laboratory of the
Buffalo General Hospital and is a
delegate to the New York State
Medical Society. Niel en wa the
first woman president of the Erie
County Medical Society.
A member of the board for
Professional Medical Conduct,
ew York tate Department of
Health, Niel en i a longstanding volunteer for the Buffalo
and Erie County YMCA. 1n
198 7, she received the
Outstanding Achievement
Award from UB's Community
Advisory Council.
Angelo Del Bal o '78 &gt; is the
author of an 800-page text for
physicians and dentists called
Maxillofacial Imaging. It describes
imaging techniques used to
detect and identify diseases and
di orders of the head and neck
area. An associate professor in
UB's Department of Radiology,
Del Balso is also the author of
Panoramic Radiography, published Ia t year.

AUTUMN 1990

Patricia K. DuHner '72

1980.~
Mark . Borer '80 &gt; is starting
a new organization "P.E.A.C.H.,"
People Educating and Advocating for Children.
Robert Braco '80 &gt; will
receive an M.P.H. degree in
May from the University of
Texa School of Public Health
in an Antonio.
Katherine Jasnosz DeCaria '80 &gt;
write "My hu band Anthony
and I are the proud parents of
Daniel Joseph, born on Sept. 15,
1989." Dr. DeCaria is a forensic
pathologist with the Allegheny
(Pennsylvania) County Coroner's
Office.
Walter iemian '80 &gt; is certified by the American Board of
Pia tic Surgery, and is now an
active member of the American
Society of Pia tic and
Reconstructive urgeons.
Sylvia Turner '80 &gt; of Dallas
has a private practice in child
and infant p ychiatry. For the

Albert Speach '82 &gt; is currently assistant professor in the
division of otolaryngology at the
University of Kentucky.
Jo Ann Pravata Pullen '83 &gt; and
her husband, William Pullen,
M.D., are the proud parents of
William icolas Pullen, born Oct.
14, 1989. William is in private
practice in internal medicine and
endocrinology in Santa Monica,
Calif.; Jo Ann practices medicine
at Cigna Health Plans in Los
Angeles.
Mark C. Steckel '84 &gt; is a
clinical instructor in ophthalmology at New York Medical
College, and director of pediatric ophthalmology and strabismus at the Metropolitan
Hospital of New York, N.Y. In
addition to his academic positions, he has a practice in
adult and pediatric ophthalmology at 4699 Main Sr. in
Bridgeport, Conn.
Deidre J. Greene '86 &gt; of
Pennsylvania writes, "My husband, Rob Dixon, and I jojned
ABC Pediatrics last July in
Allentown. We also now have a
beautiful son, Patrick, born in
October."

Janice J. Pegels '86 &gt; write ,
"Married James Jewell, M.D. on
June 10, 1989; enjoying the lake
and mountain view from our
home in Seattle."
James J. Shaughnessy '86 &gt;
writes, "I'm living in rural
Massachusetts and commuting
to Providence for a two-year fellowship in child and adolescent
psychiatry. Dale Radka '86 is in
the same program."
Jill E. Koehler '87 &gt;
announces the birth of her son,
Alejandro Daniel MarenoKoehler. Dr. Koehler is chief
pediatric resident at Hurley
Medical Center in Flint, Mich.

Obituaries
Mitchell!. Rubin, M.D., a kidney
specialist instrumental in the
development of Children's Hospital as a modem medical center,
died April11, 1990 in Charleston,
S.C. after a long illness.
Rubin, 88, a teacher, clinician, re earcher and pediatrician,
was well known for his work in
pediatric nephrology. He was a
professor and former chairman of
the Department of Pediatrics at
UB. Pediatrician-in-chief for
Children's, he retired in 1972
after 27 years of service.
After retirement, he returned
to his native Charleston, joining the Medical University of
South Carolina, where he established the Division of Pediatric
Nephrology.
The author of Pediatric
Nephrology, Rubin published
more than 70 articles in professional journals. He belonged to
14 professional societies.

BUFFALO PHYSICIA

AND BIOMEDICAL SCIE TIST

��Buffalo Physician and Biomedical Scientist
State University of New York at Buffalo
3435 Main Street
Buffalo, New York 14214
Address Corredion Requested

Non-Profir Org.
U.S. Posrage
PAID
Buffalo, NY
Permir No. 311

�</text>
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                    <text>Vol. 25, No. I

�STAFF
DIRECTOR OF PUBLICATIONS
Nancy Tobm

Dear Friends:

EDITOR
Connie Oswald Stofko

s we enter 1991, concerns that previously required only speculation now
reqUire appropriate attention and resolution. This transference will be
accelerated because of increasing fiscal constraints from all of our usual
sources of support and the changing world in which we hve. Chtef among those
concerns are a need to foster more independence and self-responsibility among
medical students and physiCians for their learning, continued development of a
research environment which will ensure continued proJuctivtty of the scientific
faculty well into the 21st century and the important need to guiJe clinical training
programs to be more responstve to social needs without harming the tremendous
contributions made to the age of specialization developed smce World War II.
For a medical schcx1l faculty, these area' of concern, as well as a multitude of
other problems which must be addressed, seem bxh overwhelming and contradictory. Nevertheless, each of this country's 126 medical sch(Xlls shares these issues
and each must present options for solutions. Given the unique circumstances at
UB, it seems that these areas of concern will receive our focus and attention
throughout the current decade. The faculty are initiating curricular changes, and
the school is providing the necessary technology and faciltties whtch will foster
educational change; the plans for the construction of a modem research facility to
be completed in 1994 are well underway, and a maJor tnstitutional commitment
has been made to mcrease the emphasis on educating and training a larger cadre
of primary care physicians while recruiting and returning an increased prop.1rtion
of residents from minority and socially disadvantaged programs. Thus, while UB
and its teaching affiliates will not be protected from the onslaught of constraints
that will continue to rx:cur, we have initiated strategies to prepare and deal with
the changing environment as we meet its challenges.
Best wishes for a happy and successful 1991.

ART DIRECTOR
Alan j. Kegler
WRITERS
Peter Askew
Lots Baker
David Htmmelgreen
judson Mead
Arthur Page
David Snyderman
Laune Wolf
PHOTOGRAPHERS
Mark Dcllas
Stmon Tong
Robert Walion
ILLUSTRATORS
Thomas Hutchmson
Thomas Rtxmey
Dan Zakroc:emskt
ADVISORY BOARD
Dr. John Naughton, Chairman
Dr. Harold Brody
Ms. Nancy Glieco
Dr. James Kanskt
Dr. oseph L. Kunz
Dr. Charles Paganelh
Mr. Michael Arontca
Dr. Antoinette Peters
Dr. Charles Pruet
Dr. Luther Robmson
Dr. Thomas Rosenthal
Dr. Saleela Suresh
Dr. Burton Singerman
Dr. Stephen Spaulding
Dr. Nelson Torre
Mr. Edward Wemke
Dr. jerome Yates
TEACHING HOSPITALS
AND LIAISONS
Batavia VA Medteal Center
Buffalo General Hosrital, Mike Shaw
Buffalo VA Medtcal Center, John Pulli
Chtldren's Hospital,
Karen Dn]a-Swterskt
Ene County Medical Center
Mercy Hospttal, Chuck Telesco
Mtllard Ftllmore Hospttal,
Joseph R. Ci{fa
Roswell Park Cancer Institute,
Judi Rtce
Sisters Hospttal, Dennis McCarthy

Produced by che Dim ton of UnivmiN
Relanons m associati&lt;m with the School of
Medicme and Biomedical SCiences, Swte
L'niverstty of New Yark at Buffalo.
Eduorial office is m 136 Crofts Hall
THE BUFFALO PHYSICIAN AND
BIOMEDICAL SCIENTIST (USPS
551--860) Winter 1991, Volume 25,
Number I. Puh!tshed by the School
of Medtctne and Bwmedtcal
Sciences, State Untverstty of New
York at Buffalo, 3435 Main Street,
Buffalo, ew York 14214. Thtrd
class hulk postage patd at Buffalo,
New York. Send address changes to
THE BUFFALO PHYSICIAN AND
BIOMEDICAL SCIENTIST, 146
CFS Addttton, 3435 Main Street,
Buffalo, New York 14214.

A

~L+-s:

John Naughton, M.D.
Vice President far Clinical Aff01rs
Dean, School of Medicine and Biomedical ScierlCes

Dear Fellow Alumni/Alumnae:

I

n September, we were happy to present the Second Annual
Distinguished Alumnus/a Award to Dr. David Nichols '47. Professor and
chairman of the Department of Obstetrics and Gynecology at Brown
University, David is a world-recognized authority on female pelvic relaxation disorders and has been a prolific contributor to the literature in hts
specialty.
It's time to start thinking ahout next year'~ honoree. Please use the
enclosed postcard for your nominations.
Our programs for students are going well and we were well represented at
the orientation sessions for the incoming University residents and for the
freshman and )Untor classes.
Mark May 4, 1991 on your calendar for Spring Climcal Day and Reunion
Weekend. This year's program, "Bridgmg the Gap Between Medicine and
Law," will be highlighted by the Stockton Kimball Lecture, given by Sol
Wachtler, chief judge of the New York State Court of Appeals. It promises
to be an exceptional program.

Smcerely,

D~

Bertram A. Portin, M.D. '53

�Vol. 25,

o. 1

Winter 1991

In Praise of Housecalls Once a staple in medicine,
the housecall is alive and well and making a
comeback.

New hours could
hurt continuity of care,
page 10.

The resurgence of
housecalls, page 4.

Residents' Hours

State~mandated changes haven't

caused the havoc educators thought they would.

Epidemiological findings
need close examination,
page 24.

Making a Team for Michael The Craniofacial
Center, a multi~disciplinary team of health care
professionals, improves the quality of life for a six~
year~old boy and a host of other children.
Danger in the Locker Room With illegal anabolic
steroid use on the upswing, reliable investigation
into its health risks is urgently needed.

Thomas B. Tomasi,
M.D., Ph.D ., receives
Stockton Kimball
Award, page 27.

Do Bad Habits Breed Disease Saxon Graham, Ph.D.,
lectures at the 1990 Annual Faculty Meeting.

Medical School News
Alumni
Classnotes

Illegal anabolic steroid use
is rampant, page 22.
Craniofacial Center brings
a smile , page 14.

�- - - ---®:- - - .r E ~ '1-

2

INTERNATIONALLY KNOWN
RESEARCHER TO SPEAK AT
(HOB LECTURE

STUDY LINKS BALDNESS,
BLOOD PRESSURE LEVELS
study of Italian factory workers has
indicated an association between
male-pattern baldness and higher
cholesterol levels and diastolic blood
pressure readings.
Maurizio Trevisan, M.D., co-principal
investigator and associate professor of
social and preventive medicine at UB,
cautions that although the study is the
first showing an association between
baldness pattern and risk factors for
coronary heart disease, it doesn't indicate
whether there's a link between baldness patterns and the disease itself
nor does it reveal the reason for the elevat~
ed readings.
Men with male-pattern baldne s had
slightly higher levels of serum cholesterol
and diastolic blood pressure (the pressure
measured in blood vessels as the heart rests
between beats) than those with either no
hair loss or frontal baldness only.
He said the differences reached statistical significance when the average readings
for men with male-pattern baldness were
compared with those for the men in the
e
other two groups combined.
- By Arthur Page

WINTER 1991

rancis S. Collins, M.D., Ph.D., associate professor of Internal Medicine
and Human Genetics and associate
investigator and chief of the Division
of Medical Genetics at the Howard
Hughes Medical Institute at the
University of Michigan at Ann Arbor,
has been chosen as the inaugural speaker for the Rose and Al Pastor Lecture
Series.
The lecture, scheduled for March 26
at the Hyatt Regency, is sponsored by
The Children's Hospital of Buffalo.
Internationally recognized, Collins'
work in recombinant DNA technology has led to several important
advances in the field, including the
location and isolation of the genes for
cystic fibrosis and neurofibromatosis
type 1.
The lecture series is an annual event
that focuses on public health issues
affecting the Western New York community.
Collins is slated to speak from 4 p.m.
to 6 p.m. A reception will follow. For
more information, call the Public
Relations Department at Children's
Hospital at 878-7543.
e

space for about 34 physicians and
researchers working on approximately $3
million worth of medical research grants.
V AMC's medical research program
includes a wide spectrum of both clinical
and basic studies. Its proximity to the UB
medical school has fostered collaborative
investigations within a variety of specialties and departments.
In addition to providing new research
space, the project included the refurbishing and expansion of 25,000 square feet
for clinical activities, outpatient care,
and administration, plus an additional
10,000 square feet for animal research.

SURVIVORS OF (ANCER
IN CHILDHOOD (AN
HAVE HEALTHY KIDS
dult survivors of two forms of
childhood cancer - Hodgkin's
disease and Acute Lymphocytic
Leukemia (ALL) -are capable of conceiving and giving birth to healthy
children, according to the results of two
recent studies conducted by Daniel M.
Green, M.D., professor of pediatrics at
UB and director of the Long-Term
Follow-up Clinic at Roswell Park
Cancer Institute.

VAMC DEDICATES NEW
RESEARCH (ENTER
he Buffalo VA Medical Center
last November formally dedicated
its new Research Building as part
of a $16.5 million expansion and refurbishing program.
The new $13.1 million facility, located
north of the medical center, provides

BUFFALO PHYSICIAN AND BIOMEDICAL SCIENTIST

�- - - ---CID:- - - .r t

~ ~

3

In the study of former Hodgkin's disease patients, some male respondents reported medically-documented
decreased sperm counts and some
female respondent reported unusual
menstrual cycles. But children born to
respondents (who averaged 29 years of
age) showed no more congenital defects
than children born to parents with no
history of the disease and none had
been diagnosed with childhood cancer
at the time of the study.
The ALL study, although conducted
among former patients who were
younger than those in the Hodgkin's ~
study, showed the same results for ~

~::;

childbirth.
"Our study suggest that children
treated for Hodgkin's disease and ALL
lead essentially normal lives after the
disease is cured," Green says.
The ultimate goal of these and future
studies is to follow these patients and
their offspring throughout their lives to
determine whether there is a genetic
risk involved with these types of cancer
and whether these former patients
develop other malignancies as they
grow older.
Counseling is an important part of
the clinic's work. "Some women who
have had these types of cancer as children are afraid to conceive and give
birth because they believe they may
have a sickly child or a child who will
develop cancer," Green says. "We are
able to reassure these patients."
The studies were conducted with
Michael A. Zevon, Ph.D., director of
the Department of Psychology at
Roswell Park and associate research
profes or at UB, and Brenda Hall, R.N.,
P.N.P./0., Department of Pediatrics.
The Hodgkin's disease study was reported in Pediatric Hematology and Oncology
and the ALL study in Cancer.
e

BUFFALO PHYSICIAN AND 1\IOMEDI AL ,

GooD NEws, BAD NEws:
BOTH LIVER AND BEER
IMPLICATED IN CANCER

IENTIST

§

matched controls, the researchers identified a "substantial increase in risk"
related to the ingestion of vitamin A in
the form of retinol from meat and dairy
foods like milk and ice cream.
On the other hand, the researchers
found no risk associated with vitamin A
derived from vegetables in the form of
carotene. In fact, the study showed risk
of esophageal cancer was lower for persons whose diets regularly included lettuce, other greens and tomatoes.
e
- By Arthur Page

STATISTICS DEPARTMENT
JOINS MEDICAL SCHOOL

1£

f you resented your mother's admonitions to "eat your liver," you'll
find solace in a recent study out of
the UB Department of Social and
Preventive Medicine.
Organ meats, like liver, head the list
of foods that appear to increase the risk
of cancer of the esophagus, according to
the team headed by Saxon Graham,
Ph.D., professor and department chair.
On what others might consider the
down side, beer (which also scored high
in an earlier UB study of dietary factors
increasing the risk of rectal cancer) also
ranks right up there in terms of riskincreasing food fare.
The study, reported in the American
Journal of Epidemiology, also uncovered
what appears to be the Jekyll-and-Hyde
personality of vitamin A, which not
long ago was being hailed by some scientists as a factor that would reduce
cancer risk.
As the result of an in-depth comparison of the diets of individuals with
esophageal cancer and carefully

he University's Statistics Department has joined the medical
school, ending uncertainty about
its fate.
Now located at 2211 Main t., the
Statistics Department is adjacent to the
Department of Social and Preventive
Medicine. This proximity is expected to
enhance research and scholarship,
school officials say, since the two departments have complementary interests.
John Naughton, M.D., dean of the
medical school and UB vice president
of clinical affairs, says that the school
will soon seek new department chairmen for both Statistics and ocial and
Preventive Medicine. He calls this an
opportunity to recruit chairs who can
bring their departments clo er together.
Associate Provost Kenneth Levy is
currently acting chairman of Statistics.
Saxon Graham, chairman of Social and
Preventive Medicine, plans to retire.
Levy said that no changes in Statistics
Department courses or programs are
anticipated in the near future but that a
faculty position will be added.
e

WINTER 1991

��s

The physician housecall is alive and well in
Western New York. After years of de . .
cline, the popularity of the home visit may
be on the upswing again,
though it isn't the same as
the housecall of the horse
and buggy days. Instead of traveling miles to check out a bellyache,
physicians now see mainly the chronically ill, newborns, and the frail
elderly.
"It's really a
time..-saver to see
homebound elderly folks
right in their homes,"
said David Holden,
M.D., professor and
chairman of UB's De...
partment of Family
Medicine.
"Frankly,
it takes longer for them
to get maneuvered out of their beds into wheelchairs, then into ambulances,
out of the ambulances, back into the chairs, into the offices, and up onto
examining tables - then repeating all these steps - than doing the home
visit.

"With newborns, I find it's nice to do the first visit in the home,

where I can get a good look at the preparations the parents have made, and
a better view of the baby's home environment. It's obviously a convenience
for the family not to have to bring the baby out of the home when it's two
to four weeks old."
BUFFALO PHYSICIAN AND BIOMEDICAL SCIENTIST

The physician housecall "still has a very important
WINTER 1991

�6

role in health care," agreed David A.
Silverstein, M.D., assistant professor
and director of undergraduate education
in Family Medicine. "It's extraordinarily
useful to see a patient's surroundings."
For example, if an elderly patient falls
frequently, a doctor on a housecall
could observe that rooms are cluttered
with potential booby traps to trip the
forgetful resident. A medicine cabinet
may reveal medications the patient
doesn't bring to the office, but which
may be contraindicated.
"You're better able to make an
informed decision as to whether a
patient - despite what he or she tells
you in the office - is comfortable and
able to make it at home," concurred
Daniel Lasser, M.D., M.P.H., clinical
director of family medicine at the Erie
County Medical Center and director of
the Urban Family Medicine Program.
Seeing one patient is useful, and visiting couples yields some extra benefits,
noted Holden, who with his wife,
Carol, a nurse practitioner, often visits
couples in their 80s and 90s.
"I gain as much information about
how one (spouse) is doing by asking the
one not being examined," Holden said.
"You can really learn what type of support system surrounds the patient by
seeing the home and talking to the people living with your patient, whether
it's a spouse, another relative, or a
friend.
"For example, if you ask an elderly
female if she's eating, the answer is
almost always 'yes'. If you ask her
daughter who's actually watching her
eat, you may get a different, and more
accurate, answer. Such added insight
isn't often available in an office visit
where a doctor's questions are directed
only at the patient."
Holden believes that housecall are
becoming more common again now
that doctors don't have to worry about
whether they can fit all of their equipment into a little black bag - everything a doctor needs is a phone call
away. During the last 10 years, the full
range of services of practically all labs is
availab le for dispatch to a patient's
home on a physician's phone order. The
services often are performed faster at

WINTER 1991

Eugene A. Steinberg, M.D., feels house&lt;aDs help redU&lt;e
the fear and isolation of many terminally mpatients.

"You can really learn
what type of support
sy stern surrounds
the patient by seeing
the home and talking to
the people living with
.
"
your patrent.

home than in a hospital.
The physician also can arrange for
physical therapy, occupational therapy,
and intravenous therapy in the home.
Lab work and therapy visits are covered
by major in urance carriers, Medicare,
and Medicaid.
Home visits help make many people
comfortable, and reduce the fear and
isolation which many chronic or terminally ill patients face, said Eugene A.
Steinberg, M.D., clinical assistant professor of medicine and family medicine
and a member of UB's Division of
Geriatrics and Gerontology.

"We talk to people, listen to people,
and deal with the fears that block the
learning in the hospital," said
Steinberg, who is also medical director
of the Buffalo VA Medical Center's
Hospital Based Home Care Program.
The program at the VA is special
because patients are seen in their
homes not just by a doctor, but by a
team that includes nurses, social workers, a dietitian and a physical therapist,
Steinberg noted.
Many of the patients the team sees
have chronic illness and are stable,
such as those who have suffered a
stroke or multiple sclerosis.
There's also a growing group of
patients who are discharged from hospitals sicker and unstable and who are
continually readmitted. The team finds
that early intervention, such as making
small changes in medication, often
makes a big difference and can even
keep the patient out of the hospital.
This not only helps the patient, but
saves the hospital money.
The team works closely with the
oncology unit at the VA Medical
Center, providing compassionate posttreatment care for terminal patients, in
areas such as pain control, psychological issues, and generally aiming to
improve the quality of life.
"It's a very different focus from acute
care," Steinberg noted.
Another group of patients seen by
the VA team is those with multiple
medical problems.

BUFFALO PHYSICIAN A D BIOMEDICAL SCIENTIST

�Assistant professor and director of faculty development and continuing education in the Department of Family Medicine, Roseanne C. Berger, M.D., prepares students
0
to determine exactly what they can learn from a housecall."

"The housecall by the full team is
extremely valuable in untangling confusing symptoms," Steinberg explained,
"and in addition provides an excellent
opportunity for effective one-to-one
education with patients on their turf on
how to watch their bodies."
If housecalls seem like a well kept
secret, it's because physicians haven't
promoted or advertised that they make
housecalls, said Robert A. Baumler,
M.D., an internist, cardiologist, and
clinical assistant professor of medicine
at UB. That's because many people mistakenly think they can routinely call a
physician to their house for whatever's
wrong with them. Doctors can't make
housecalls for everything because the
travel time would consume their day.
Another drawback to housecalls is
that they may keep patients from getting much-needed activity - there is
therapeutic value in getting dressed up
for an office visit and getting out for
some fresh air, some doctors assert.
BU FFALO PHYSICIAN AN D BIOMEDICAL SCIENTIST

Critics also argue that medical insurers, including Medicare, don't adequately acknowledge the value of
housecalls. Reimbursement rates don't
come close to covering costs.
Marshall Clinton, M.D., emeritus
clinical professor of internal medicine

at UB, recalls he "used to make a lot of
housecalls, and was trained to do so.
You could do a lot for people at home
that you couldn't do any other place."
Although he still makes calls on
selected longtime patients, Clinton says
he's one of the physicians who is fed up

PRESCRIBING HOUSECALLS
House calls are best used when:
e It's helpful to assess the home situation, especially for the elderly and
newborns.
e A patient's condition would be
adversely affected by being transported
to the office.
e A terminal illness affects a longtime patient who may not require hospitalization, but may need a medication change or other support.
e Transporting the patient for an
office visit would be a hardship or impos-

sibility for family members or friends.
e It's more convenient for the
physician. If a parent calls at 5 p.m.
about a fairly well-defined condition in
a child that's not likely to require
extensive lab work, such as an earache,
the doctor may find it easier to pay a
house call than wait for the family to
get to the office.
-Thomas C . Rosenthal, M .D., clin-

ical associate professor and director of residency education in family medicine at

UB

WINTER 1991

�8

Early intervention, often possible only through home visits, tan signifitantly improve outtomes.

with government regulations and inadequate reimbursements.
"I rather expect I'll be retired within
a year," Clinton confided.
Despite the drawbacks, the Family
Medicine Department remains convinced that there is a place for the
housecall. According to a survey by
Roseanne C. Berger, M.D., 16 of 26
full-time faculty members in the department visited patients' homes during the
past year.
Starting this year, all new family
medicine interns are receiving an orientation lecture on housecalls by
Berger, who is assistant professor and
director of faculty development and
continuing medical education in the
Department of Family Medicine.
"We need to prepare (future) physicians to determine exactly what they
can learn from a hou ecall," she said.

WINTER 1991

"It's important to
get students in
their formative years
to become familiar
with what can
be done for people
in the home . "

Some students in family medicine
already accompany faculty members on
housecalls, and Berger would like to see
that opportunity extended to all medical students.
"It's important to get students in
their formative years to become familiar
with what can be done for people in the
home," she said.
There are many resources available to
provide care for people at home, such as
visiting nurses or X-ray services, but "I
don't think students appreciate it unless
they see that in action," she said.
Berger notes that doctors are trained
in a very high- tech world, and may
appreciate being exposed to the
low-tech surroundings of a patient's
home.
Janet V. Johnson, a fourth-year medical student, said she "found it refreshing
and mildly surprising to learn that
BUFFALO PHYSICIAN AND BIOMEDICAL SCIENTIST

�physicians - not just visiting nurses
alone- actually make housecalls."
She says she not only finds housecalls interesting and helpful, but after
making just one call was firmly convinced they'll be an integral part of her
own practice.
"On my first visit," Johnson recalls,
"we were going to see a 51-year-old
bedridden man who was cared for by his
78-year-old aunt. When I saw her age
in the written report, I was naturally
concerned about her ability to function
effectively at her age.
"But when I saw the aunt at work in
the home, my mind was immediately
placed at ease because she seemed
much younger than 78- and fully
capable of handling things. Instead of
her age being a concern, the visit put
fears to rest."
Johnson's evaluation of the home
visit summarizes that of many practicing physicians: "I enjoy it, and you can
learn a lot from it."
e

TIME-HONORED PRACTICE
DESERVES TO MAKE A
COMEBACK
orman Chassin, M.D., '45, muchhonored senior statesman of the
Western New York medical community, considers housecalls so valuable
that when poor health robbed him of
the vigor to continue them, he ceased
practicing medicine altogether.
"I never lost anything from going
into a home, and I a lways gained
immensely," Chassin said. "There is no
questioning the rewards in terms of new
information about the patient's lifestyle.
This information is the cement that
fills in the cracks of one's understanding
of a patient."
"The whole physician-patient relationship is fundamentally enhanced," he
continued. "The physician has answered
the patient's call totally, bodily. That is
not the same as answering the phone or
being in the office. The whole transfer
phenomenon, the psychological aspect
of the relationship, is benefited."
Chassin is respected by patients and
physicians alike. When he retired, his
patients established the Norman
BU FFALO PHYSICIAN A D BIOMEDICAL SCIENTIST

"There is no question the housecall is a plus. The
primary concern of the physician is problem--solving
for the patient, and there is much that can be
learned from the patient's setting. We are sometimes
surprised with entirely new information that affects
management of the patient's problem."
Chassin Endowment Fund at the Erie
County Medical Center, where Chassin
spent more than 20 years as attending
physician. The fund provides an annual
stipend to the outstanding intern in
internal medicine at the center.
He holds the Kenmore Mercy
Hospital Foundation's highest award for
service to his patients and the community. James Nolan, M.D., director of
medicine at ECMC and chairman of
the Department of Medicine at UB,
considers Chassin one of the leading
clinicians in internal medicine in the
Western New York area.
Chassin was instrumental in forming
the Committee on Human Values and
Medical Ethics at UB, and with organizing the first meeting of clinical chiefs
of medicine from area hospitals.
Hundreds of medical students have
benefited from Chassin's knowledge,
which is imbued with extraordinary
compass ion and concern for the
patient's emotional, as well as physical,
well being - an outgrowth of Chassin's
long interest in psychiatry. He was
headed for a career in the field when he
switched at the last moment to internal
medicine.
Chassin believes that medical treatment should be personal, that ideally
physicians should form long-term relationships with their patients, garnering
as much information as possible about
their lives. Rooted in this belief is his
respect for the value of housecalls.
"There is no question the housecall is
a plus," Chassin said. "The primary
concern of the physician is problemsolving for the patient, and there is

much that can be learned from the
patient's setting. We are sometimes surprised with ent irely new information
that affects management of the patient's
problem.
"Physicians must be aware of the
social factors- the patient's immediate
family, as well as cultural, ethical, legal
and economic constraints. Rarely can
one attend a patient in just the physical
sense."
Making housecalls meshes w ith
another Chass in opinion of h ow
medicine should be practiced - slowly
and patiently.
"Nowadays new students and physic ians feel they n eed to do something
quickly," he said. "I teach that certain
diseases and illnesses take a basic natural course, and that time is an important element. Sometimes it is better not
to jump in with aggressive therapy, but
to wait for the appropriate moment.
"And for many patients, home is a
better, even safer, place to heal than the
hospital," he said.
"Considering all the risks of being in a
hospital today - technology gone wild,
infection running rampant - home can
be better for certain given conditions.
"Obvious benefits aside, if housecalls
are returning to favor now," Chassin said,
"the impetus is probably economic."
"The government and other payors
have realized that in certain instances,
the home call will benefit the payor
more than some sort of call in the doctor's office," he said. "If you make the
econom ic rewards high enough, the
housecall will return."
e
- By Lois Baker
WINTER 1991

9

�10

n 1989, New York became the first state government to step in and tell medical
hools and teaching hospitals how to run their residency programs.
intervention- intrusion to some- came in the areas of work hours, supervision,
and credentialing. (See box for details.)
After living with the regulations for a year, the reaction ofUB faculty and residents is still
mixed, depending in great part on specialty. But many concede that the regulations aren't as
bad as they had feared.
SURGEONS ARE STILL UPSET

"What you see now is more attending staff working with
more junior residents," Hassett said. "In the past, a third-year
Surgery was- and is still- the medical service that is least
comfortable with the regulations.
resident might have helped a first-year resident, but now the
When the regulations
first-year resident is likely to be
getting instruction from a 40were proposed, Lewis Flint,
or 50-year-old attending physiM.D., who was chairman of
cian who has far more experisurgery at UB, said that they
ence. We might get an educawould damage surgical educational windfall out of that."
tion so much that it would be
But he is troubled by the
better to close the program than
overall effect of the regulation
comply. Flint delivered himself
on surgeons' education.
from their restrictions by ac"There is a practical fivecepting a position at Tulane
year limit on post-graduate
University in New Orleans.
education in surgery because
"My sense is that most of
coulf/ ~UtH! &amp;~n U LOP.)P.
you can't get anyone to pay for
our residents are not happy with
more," he said. "And if you cut
them," says James Hassett Jr.,
~a/~ 'o/,,&amp; /io/bJ an&gt; .;h~~
the amount of time available to
M.D., associate professor and
residents in those years, you cut
chairman of the Task Force on
clinical
exposure."
Graduate Medical Education
According to Hassett, the
in the Department of Surgery.
BY JUDSON MEAD
bottom line is how indepen"They don't like anything
dently the resident can act when
forced down their throats. They
he or she is finished with the
just want to operate and anyresidency. Hassett worries that some of a resident's education
thing that restricts their chance to do that is perceived as a
negative."
may be shifted from residency to practice.
"The essence of surgical education is repetition," Hassett
Some residents simply ignore the rules, Hassett said. If
said. "The important thing is how many complex procedures
they aren't finished with their work, they stay beyond the time
allowed, even though the new regulations have built in extra
has a resident been exposed to and how many times a resident
time for surgical residents.
has repeated simple procedures."
Surgical residents are allowed to be on call past the normal
hours limit if they are "generally resting" with "infrequent"
OTHER DEPARTMENTS ARE CONCERNED
interruptions for patient care. The exceptions apply only if
The view is generally more positive outside of surgery, but
residents are on call no more than two time a week and have
people's concerns haven't vanished.
a 16-hour rest period after they go off duty.
In the Department of Medicine, the move to an SO-hour
In its attempt to comply with the new regulations, UB's
week for residents was coming one way or another - its
surgery program has created a patchwork of different rules in
national accrediting body implemented the change nationdifferent hospitals, such as instituting a regimen of night
wide shortly after the New York regulations were put in place.
coverage. The side effect is that there are fewer residents on
'The house staff likes the changes," says Alan Saltzman,
duty during the day, spreading them thinner.
M.D., clinical associate professor of medicine at UB and
Even if the hours requirement has surgeons steaming,
clinical director of the Department of Medicine at the Erie
some of the supervision requirements are viewed as positive.
County Medical Center. "They've clearly been 'decompressed."'

:7/

WINTER 1991

BUFFALO PHYSICIAN AND BIOMEDICAL SCIENTIST

�In addition to giving residents a more humane schedule,
the changes have "put more emphasis on the role of the
attending physician, which is a benefit."
But there are still worries about the effects on education
and patient care. Gerald Logue, M.D., chief of staff at the
Buffalo VA Medical Center, calls the regulations "a detriment
to education."
The problem Logue sees is with continuity: continuity of
patient care and continuity of resident education.
If a patient comes in at night, the night float (a resident
who covers two or three different specialty services) does the
workup, a different team sees the patient the next day, and yet
another team sees the patient the next night. Because residents
must take a whole day off every
week, they often have to drop
out of a patient's care, which
decreases its educational value.
"It's hard for residents to
follow a case," Logue says, "and
hopefully patient care doesn't
suffer."
Even if patient care hasn't
suffered, there is no evidence
that it has improved now that
hours are reduced, notes
Saltzman. Yet the state based
its regulation of hours on the
assumption that long hours were
detrimental to patient care.
A Minnesota study published in the November/December 1990 edition of the

]ournal of General Intemal Medicine showed that the outcomes
for patients who were cared for by the admitting resident were
the same as the outcomes for patients who were admitted by a
night float and cared for by a different team of residents,
Saltzman noted .
However, disrupting continuity of care can be expensive,
he added. The study found that patients who weren't treated by
the admitting resident stayed in the hospital longer and received more lab tests.
"It's hard to say whether we've gained as much as we've
lost," Logue said. "We don't have people walking around who
haven't slept for 36 or 48 hours. But the law encourages a shiftwork approach to medicine that is incompatible with what
residents will encounter in practice in the real world."

would be.
"The mood is settling out," Naughton said. "The initial
mood was that this would be disastrous for training, but this has
not been borne out.
"As far as education is concerned, I think the effects have
not been adverse. In fact, what's happened has probably been
positive."
Whether the regulations are driving the best young doctors from choosing New York State residencies, as some had
feared would happen, is difficult to tell, Naughton noted,
because other factors also affect residents' choices. Downstate,
for instance, the biggest problem in recruiting residents is the
large number of AIDS cases.
"My feeling is that recruiting for Buffalo has gone
fairly well this year," Naughton
said.

INFLEXIBILITY
IS A DRAWBACK
In Obstetrics and Gynecology
Myroslaw Hreshchyshyn, M.D.,
professor and chairman of the
department, says that, on balance, the regulations have
benefited resident training and
patient care. However, there
are drawbacks.
"The negatives are cost,
loss of flexibility in handling
things as we (the departments)
think best, and the creation of
expectations that are not always reasonable," he said.
Hreshchyshyn thinks the residents in his department are
generally pleased with the regulations, but adds that he senses
that they are coming to regard the limitation on hours as an
entitlement.
"The law takes away flexibility in terms of assignment and
continuity of care," Hreshchyshyn said. "In this respect it is no
different than any other work rule specifying when you can take
a coffee break and so on."

MOOD IS SETILING OUT

Well before last year, Obstetrics and Gynecology was
moving toward voluntarily providing supervision by faculty
members at the level now mandated. When the regulations
were implemented, Hreshchyshyn warned that the cost of
requiring, rather than encouraging, the increased supervision
would be a problem. His view is the same now.

Summing up the situation, John Naughton, dean of the medical school and vice president for clinical affairs at UB, says most
people think the regulations aren't as bad as they thought they

"This is a costly proposition for the hospitals," he says.
"With time it will become routine. The net result is that we
have added a very costly component to hospital services."

BUFFALO PHYSICIAN AND BIOMEDICAL SCIENTIST

WINTER 1991

11

�12

SUPERVISION, NOT HOURS, IS THE KEY
Supervision, not the hours requirement, is the key part of the
change, according to George Ennis, senior hospital administration consultant at the New York State Department of Health.
"The hours-business got distorted out of proportion at the
expense of the supervision issue," he said.
Most hospitals in the state are working assiduously to
comply with the regulations, Ennis said, and most residency
programs have provided the funds needed for supervision. The
department has received some complaints about non-compliance and has cited some programs.
It is the consensus in Buffalo that local hospitals have had
an easier time complying with the regulations than downstate
hospitals.
"Teaching hospitals in
Buffalo have always had rather
rigid standards," said Luther
Musselman, M.D., director of
medical education at Millard
Fillmore Hospital and clinical
associate professor of medicine.
He thinks the changes have
worked for the better elsewhere,
especially with respect to
tightening supervision downstate.

HURRAH FOR
CREDENTIALING
Of the three components of
the law, the one concerning
credentialing has generated
the most enthusiasm locally,
even though it has also generated more paperwork.
"The credentialing has been positive because it forces us to
scrutinize more closely what residents can and can't do and
how good they are," said Hreshchyshyn ofOB/GYN, adding that
his department is now doing a better job of monitoring both
residents and their supervisors. The department absorbs the
extra cost this entails.
In the Department of Family Medicine, which was already
in compliance with the hours regulations, the credentialing
requirements have caused the department to formalize what it
was doing by keeping better records, noted Thomas Rosenthal,
M.D., director of the family medicine residency at UB and
clinical associate professor.
The internal medicine program at Millard Fillmore Hospital developed an extensive credentialing protocol in 1988
before the new regulations appeared. It specified the criteria for
gaining privileges for each procedure a resident encounters
during training.

WINTER 1991

The internal medicine protocol was then used by UB as a
model for the rest of its departments in the Western New York
Consortium for Graduate Medical/Dental Education, which
coordinates all of UB's residencies at the various hospitals.
Credentialing decisions are made by the director of each
program. Among all of the training programs in Buffalo, there
are 275 procedures which require credentials (for example,
inserting an IV line).
Keeping track of the credentials of the 615 residents has
been streamlined by centralizing the information on computer.
All consortium hospitals have access to that computer information.
"What this has led to is the possibility of much more
information exchange between
members of the consortium,"
says Saltzman of ECMC. "But
whether we're teaching better
or just creating a better paper
trail is a question."
Musselman of Millard
Fillmore says that the formalization is a good idea because
credentialing in the past was
more impressionistic. Now
computerized data on procedures completed is forwarded
to the chairman so he or she
has better information on
which to base a decision.

COST IS A HURDLE
While New York is still the
only state to directly regulate
residency training, others are
watching.
"The issue has to do with the whole structure of postgraduate medical education," said Ennis of the Department of
Health. "The American College of Physicians, the American
College of Surgeons, other states, and the federal government
are all looking hard at what New York is doing."
Indeed, the 80-hour limit on residents' work hours is either
under legislative consideration or discussion in several states,
including California, Pennsylvania, Illinois, Minnesota, Connecticut, and New Jersey. And in] une 1989, the AM A's House
of Delegates passed a resolution by its Resident Physician
Section endorsing the SO-hour limit.
The biggest hurdle for the states is cost.
About two-thirds of the expense the regulations impose
on hospitals has been covered by increased reimbursements,
either from the state or, in the case of the VA hospitals, the
federal government.
At the Erie County Medical Center, Assistant Adminis-

BUFFALO PHYSICIAN AND BIOMEDICAL SCIENTIST

�trator Thomas J. Faith says that at the moment money is not his
chief concern.
"The money is there to hire ancillary staff, but the problem
is finding them," he said.
Marcia Brierly, administrative director in the Department
of Medical Education at Millard Fillmore, believes that the
financial impact will show more clearly in the future.
"It's dangerous that the hospital is absorbing so much of
the cost of the regulations," she said.

RESIDENTS' MORALE IS HIGH
But Brierly has also observed a positive change on a human
level.
"The biggest impact of the
regulations on residents is in
their morale," she says. "I hear
the same thing from people
around the state: we didn't see
the mid-winter depression
we're accustomed to in residents."
Lisa Benson, M.D., a thirdyear resident in internal
medicine, credits the hours
limit with some improvement
in the quality of her life.
"There's been a real difference - for the better," she
said. "There may be a slight
deficit in continuity of care,
but I don't think it's been significant, and I don't think the
change has had an adverse
impact on education, either."
While surgery residents complain that the regulations
make their hours too short, some residents think it's still not
short enough. Timothy Gundlach, M.D., who started his
residency in surgery, moved to anesthesiology this year, a
department that was already in compliance with the regulations before they took effect.
There's a camaraderie among surgery residents that tends
to minimize complaints about the long hours, he said, but that
wasn't enough for him. With only 50 or 60 hours a week spent
outside the hospital, there wasn't enough time left for reading
or even to conduct a personal life.
Gundlach noted that there's a general feeling that if more
support staff, such as IV teams, could be hired, it would take the
pressure off surgery residents. People are leaving because there's
too much work.
NashatRabadi, M.D., chief resident in medicine at ECMC,
says of going home to bed after being on call: "That was a real
pleasure."
e

BUFFALO PHYSICIAN AND BIOMEDICAL SCIENTIST

13

HOURS
Residents may be scheduled for no more than 80 hours a
week, when averaged over four weeks.
They may be scheduled forno more than 24 hours in a row.
On-duty assignments must be separated by at least eight
hours of non-working time.
Residents must get 24 consecutive hours off each week.
Hospitals must enforce policies that prohibit combined
assigned hours and moonlighting hours from exceeding the limits on assigned
hours.
In certain departments that
don't have a high volume of
acutely ill patients and where
the resident is able to get
enough rest, there is more
flexibility in scheduling. (Excluded from this clause are
anesthesiology, family practice, medical, surgical, obstetrical, orpediatricservices.)
Surgery residents can be on
call past the hours limit if they
are "generally resting" with
"infrequent" interruptions for
patient care. The exceptions
apply only if residents are on
call no more than two times a
week and have a 16-hour rest
period after they go off duty.

ON-SITE SUPERVISION
A sufficient number of supervising physicians must be
present in the hospital 24 hours a day in the acute care
specialties of anesthesiology, family practice, medicine, obstetrics, pediatrics, psychiatry, and surgery.
Supervising physicians must be board certified or board
admissible, or have completed a minimum of four years of
postgraduate training.
The supervising physician may be a resident in his final
year of post-graduate training if the patient's physician can
get to the hospital within 20 to 30 minutes of being called.

CREDENTIALING
The medical staff must provide written documentation of
patient-care privileges granted to residents.
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ts beginnings were casual meetings in the halls and conversations in the OR lounge at
Children's Hospital about five years ago. Sometimes the discussions were prompted by a
special patient who had a disfigured face along with problems hearing, speaking, and eating.
Other times, the physicians would talk about patients who had more common
disorders involving the head and face, such as cleft lip and palate. The doctors were
concerned because these patients were being shuttled from specialist to specialist almost
unendingly and some of the older children were out of school for surgery more than they
were in school.

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BUFFALO PHYSICIAN AND BIOMEDICAL SCIENTIST

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The disconnected conversations
finally found a direction with the development of the Craniofacial Center of
Western New York.
The center, begun in 1988, maintains
a unique interdisciplinary team
approach to diagnosing and treating
patients who have disfiguring and disabling conditions of the head and face .
It is based at Children's Hospital and
has ties throughout the University and
community, according to Joseph
Bernat, D.D.S., M.S., who heads the
center's board of directors and is chairman of pediatric dentistry at the UB
School of Dental Medicine.
One of the patients who influenced
Bernat and colleagues to start the center is six-year-old Michael Manthey,
who has presented one of the center's
most challenging cases. Many of the
doctors now associated with the center
have been treating him since his birth,
and continued treating him when the
center was organized.
Michael was born with a rare genetic
disorder known as Nager's syndrome.
This disorder is characterized by severe
underdevelopment of the lower face,
hearing loss, and limb abnormalities,
according to Robert Perry, M.D., clinical assistant professor of surgery (plastic), otolaryngology, and oral/maxillofacial surgery at the UB medical school
and member of the Craniofacial
Center's board of directors.
Michael had almost no chin; his
lower jaw was deformed and retrusive.
His tongue is small, he has hearing
problems, and he is missing fingers on
each hand.
His treatments aimed first to help
him breathe and take nourishment.
The later therapy helped him to communicate and to chew, as well as
improve his appearance.
When Michael was born he had to
receive a tracheostomy to open an airway, as well as a gastrostomy so he
could be fed using a tube that entered
his stomach through the abdominal
wall. He only needed the gastrostomy
as an infant to ensure that he got adequate nutrition, but he may always
need the tracheostomy.
Since his birth, Michael has undergone
multiple surgeries on his hands, and has
WINTER 1991

been evaluated for laryngeal problems.
"Last year we began to organize a
treatment plan for reconstructing
Michael's lower face," said Perry.
Because Nager's syndrome is so rare, the
team consulted specialists from craniofacial centers in New York, Toronto,
and Dallas, he added.
The first course of action was surgery
to examine Michael's airway and
expand his chin and neck tissue to
make room for his new jaw. The next
step was to begin expanding the jaw
bone, Perry stated.
The team used a technique known as
the llizarov procedure, which was
developed in the 1950s in the Soviet
Union to stimulate bone growth.
Until recently, this procedure was

primarily used to lengthen limb bones.
It uses an externally fitted apparatus
that is placed over the area where bone
growth is required. In 1987, two UB
physicians, Monroe Strong, M.D. and
Robert Gillespie, M.D., were the first in
North America to use the MonticelliSpinelli External Fixation System to
promote bone growth in a patient who
had a badly infected broken leg.
Michael wore a modified version of
that device that was fitted over his
head and face, said Bernat. It looks like
a halo and is securely anchored to his
skull. Surgeons cut through both sides
of the lower jaw bone, creating fracture
sites. The apparatus holds the fracture
sites open.
As in a broken bone, new bone grows
BUFFALO PHYSICIAN AND BIOMEDICAL SCIENTIST

�between the fracture sites. As new bone is
laid down, the apparatus is adjusted daily
to open the space slightly between the
fractures, stimulating more bone growth.
The result is that now Michael has a
more fully developed lower jaw and chin.
The next step will be to reconstruct his
jaw joints in order to get his jaw to open
wider. When the joints are reconstructed, he will be able to chew better.
Michael also received help for his
other related problems. He wears a
hearing aid and communicates through a
combination of speech, sign language,
and a computerized speech board, noted
Sanford Nusbaum, D.D.S., clinical associate professor of oral and maxillofacial
surgery at UB's dental school and a board
member at the Craniofacial Center.
"He pushes a button and it says 'Hello
Dr. Nusbaum,"' Nusbaum reported.
In spite of his disabilities, Michael is
attending regular first grade and doing
quite well emotionally. Michael's family
is a pillar of support and very much
involved with the success of his treatment, the staff noted.
Michael's case is one of the few times
mandibular (jaw) bone elongation has
been done on patients in the U.S.,
Perry said, noting that the success of
Michael's treatment reflects just how
important it is for specialists to combine their expertise and resources. This
is what sets the Buffalo center apart
from the others.
"Most centers revolve around a single
surgeon who does the majority of the
work," Perry explained.
Bernat said that this individual
becomes "the dominant force, and then
the team takes on the personality and
flavor and the bent of that individual
profession."
"We wanted to get away from that
model so that everybody's contributions
are considered and nobody feels as if
they're left out," Perry said. "You can
see that in our conferences. Everybody's
opinion is respected."
"No one part of the team is more
important than any other part of the
team," Bernat added. "So, the psychologist is just as important as the surgeon."
One of the most common congenital
disorders treated at the center is cleft
lip and palate (CLP).
BUFFA LO PHYSIC IAN AN D BIOMEDICA L SCIENTIST

Michael'S case is one of the few times
mandibular bone elongation has been done
on patients in the United States.
The success of his treatment reflects just how
important it is for specialists to combine their
expertise and resources, and it is what sets the
Buffalo center apart from the others.
CLP, which arises during the embryological development of the fetus,
results in the incomplete closure of the
palate and an abnormal cleft between
the upper lip and the nose. CLP occurs
in about one in every 700 live births.
The relatively high incidence of this
birth defect accounts for about 61 new
cases every year in Western New York.
Some children with CLP also present
other associated problems which could
be overlooked and come back to haunt
these children later, noted Linda
Brodsky, M.D., who is associate professor of otolaryngology and pediatrics at
the UB School of Medicine and
Biomedical Sciences and is on the board
of directors of the Craniofacial Center.
For instance, some children born
with CLP also suffer varying degrees of
hearing loss which may affect their
speech development. Many physicians
and dentists may not be familiar with
the subtleties of these syndromes,
Brodsky commented, and they don't
know about new treatments and procedures. The center serves as a repository
for tried and tested treatments as well
as for new technology and the sharing
of seminal ideas.
And in no better forum can the sharing of ideas and opinions be heard than
during the monthly patient conferences, which are held at Children's and
open to all individuals interested in
craniofacial disorders, said Bernat.
At each conference, a lecture on a
specific topic is presented to the audi-

ence. Then one or more cases are
reviewed with the actual patients present. Any of the specialists can examine the patients and review their histories and charts.
After the patients leave, the specialists
begin their debate about the best plan for
treatment. The goal is to get a variety of
opinions from all the specialists.
"We talk it out - sometimes fight it
out," Brodsky said.
In the end, everybody must be satisfied with the treatment plan, she
explained. It's not enough for an oral
surgeon to get up and say "I want to do
a bone graft now." Not only does he
have to convince other oral surgeons in
the group that this is the right thing to
do, he must convince the other specialists as well.
Most children born with craniofacial
disorders are seen by team members
immediately- right in the delivery room
at Children's Hospital. (Those born at
other hospitals may be transferred to
Children's if the condition is severe.)
In the delivery room, the breathing
of newborns with craniofacial disorders
is checked. If there's a problem, an otolaryngologi t is called in and may perform a tracheotomy to open an airway
in the neck.
A few days later, once the physicians
are sure the infant is breathing and
feeding properly, Luther Robinson,
M.D., examines the infant for possible
genetic disorders. Robinson, director of
Clinical Genetics and Dysmorphology
WINTER 1991

17

�18

llizarov's Procedure, developed in the Soviet Union
in the 19SOs to stimulate bone growth, was used to
lengthen Michael's jaw through the use of an externally fitted device.

in the Division of Human Genetics at
Children's and assistant professor of
pediatrics at UB, is also on the board of
directors at the Craniofacial Center.
Once this diagnosis is made, the team
will have a better idea of how the disorder will behave and progress. From
there the doctors are able to make a
prognosis.
Craniofacial patients generally
require years of treatment. For example,
patients with CLP may require between
four and six surgeries to repair the lip
and palate, and may also have to have
their dental arches expanded through
bone grafts. Treatment will last through
their teen years, said Nusbaum, the
maxillofacial surgeon.
Many of these procedures are timed
according to the eruption pattern of the
permanent teeth, he added, and this
stretches out the treatment period.
ln addition, these children "have to
be monitored for speech and often they
need the help of a speech and language
pathologist," commented Nusbaum.
Because people are concerned about
their looks, a person who has never
looked right or sounded right or chewed
right may need counseling, as may their
families. Success for a patient may be
measured in small victories, resulting in
a great deal of stress.
Older children and even adults are
treated at the center, Nusbaum said,
adding that the younger patients tend
to respond somewhat better to treatment because they're still growing and
WINTER 1991

I
don't have to relearn speech habits.
The coordination of the center's activities requires a monumental effort on the
part of support staff. Two of the people
who are responsible for keeping the center running smoothly are Deborah
Green and Janice Rockwood, R.N.
Green, who handles secretarial

duties, is helping to set up a fee structure that should save patients money.
Patients will be charged a flat fee for
evaluations by the team, rather than
being billed by individual specialists.
The treatments themselves generally
are covered by insurance, and patients
with congenital deformities often are
BUFFALO PHYSICIAN AND BIOMEDICAL SCIENTIST

\

�eligible for state assistance.
Rockwood, a nurse at C hildren 's fo r
15 years who h as worked in just about
every department, began working at the
center last year.
"I am a patient advocate," sh e sa id.
"Th a t 's m y m a in jo b . I h ave th e
responsibility of sch eduling pa tie nts
for their appo intments and surge ries,
t h e ir preo p e ra tiv e proc edures, a nd
patient education ."
Rockwood also gives invaluable advice
on things such as referrals and payment,
and acts on behalf of the patients when
they see doctors who are not part of the
center. Finally, Rockwood se rves as a
sounding board for patients to air their
frustrations, fears, and hopes.

Because of their enthusiasm fo r the
interdisciplinary approach , the team is
lobbying lawmakers in Albany to find
resources so that other craniofacial cen ters can be started up through out th e
state, Perry said.
In creating a state-wide network of
centers, patient care will be enhanced,
the number of surgeries reduced , and
costs will come down, Brodsky added .
The center has already taken on an
international flavor. During June 1989,
members of the craniofacial team spent
two weeks in the Dominican Republic
on an informational exchange miss ion .
They spent time diagnosing patients
and even operating on nine children .
S ix footlockers of supplies and equip-

ment , which were don ated by S isters
H os pital a nd C hildre n 's H ospita l of
Buffalo , we re delivered to C hildren's
Hosp ital in the Dominican Republic,
Perry said .
19
The team also tra ined some of the
loca l phys ic ia ns on n ew techniqu es.
Th e t ea m will b e returning t o th e
Dominican Republic in N ovember to
strengthen ties and share more of their
information, he added.
Future success of the C ra niofacial
Center depends upon continued integration of the various fields of expertise.
The team encourages those interested
in treatment, education, or research of
craniofacial disorders to get in to uch
with the center at (716) 878-7149. e

Craniofacial Center's Aim: lmproYing uality of Life

W

hen people usually think
about a craniofacial treatment center, they think
about corrective surgeries
that change the way a person looks,
noted Linda Brodsky, M.D., who is
associate professor of otolaryngology
and pediatrics at the UB School of
Medicine and Biomedical Sciences
and is on the board of directors of
the Craniofacial Center.
Here, the concern is not just with
correcting deformities, but more
importantly, making sure that the
patient functions reasonably well,
stated Brodsky, who is also a
co-head of the Department of
Otolaryngology at Children's
Hospital. The aim is to improve the
overall quality of life.
"The center is multidisciplinary
in that there are many disciplines
involved, but it's also interdisciplinary in that all of the disciplines
are intertwined," said Joseph
Bernat, D.D.S., M.S., who heads
the center's board of directors and
is chairman of pediatric dentistry
at the UB School of Dental
Medicine . "We work very closely
with one another, and that's something that we stressed from the
very beginning."

BUFFA LO PHYSICIAN AN D BIOMEDICAL SCIENTI ST

More than 20 health care specialties ore represented in the Craniofacial (enter.

In all, more than 20 health care
specialties are represented in the
Craniofacial Center, including
genetics; pediatric dentistry; speech
pathology; audiology; psychology,
and plastic, oral and maxillofacial
surgery.
The center currently treats over
200 patients, most with congenital
deformities. Treatment generally
starts at birth and lasts through the
teens, though some adults are also
treated.
The center also focuses on education for the team members and residents, and it's beginning an aggres-

sive research program as well, added
Robert Perry, M.D., clinical assistant professor of surgery (plastic),
otolaryngology, and oral/maxillofacial surgery at the UB medical
school and member of the
Craniofacial Center's board of
directors.
The research program includes a
new investigative project on the
efficacy of various procedures to
lengthen the jaw bone. Initially,
researchers will use animal models
to test these procedures. Eventually
they hope to apply their findings to
e
humans.

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n 18~year~old body builder takes several

types of black market steroids and gains

130 pounds of lean muscle over the next three years.

He also experiences fits of depression, violence and

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delusions of grandeur. Convinced of his omnipotence,

he drives his car into a wall at 30 mph, after enlisting

a friend to videotape the crash.
BUFFALO PHYSICIA

AND BIOMEDICAL SCIENTIST

WINTER 1991

�22

...................................................................................

These are just two examples of the increasing
misuse of anabolic steroids
and human growth hormone
that have come to the attention of researchers W. J.
Kraemer, Ph.D., director of
research at Pennsylvania
State University'sCenterfor
Sports Medicine, and Karl
Friedl, Ph.D., a research
physiologist with the U.S.
Army Institute of Environmental Medicine.
Presenting a paper on
the topic at last August's
Congress of the International Society ofPsychoneuroendocrinology, which was
co-sponsored by UB, the pair said that
reliable investigation into the health risks
of steroid use is urgently needed.
Mere scare tactics in the media, Friedl
noted, are unlikely to discourage athletes
from pursuing a competitive edge with
hormones. Instead, the negative publicity surrounding steroids undermines their
legitimate applications and impedes scientific study.
Kraemer, a member of the U.S. Olympic Committee and the National Strength
and Conditioning Association, made a
plea for increased drug testing, better role
models in athletics, research into alternative training methods, and rehabilitation
for athletes habituated to steroid abuse.
Anabolic steroids are synthetic de-

increased significantly
among athletes, mostly male,
and has even spread to
nonathletes who want only
to improve their appearance.
Friedl cited a recent study of
12th-grade males in the
United States that showed
that almost 7 percent use or
have used anabolic steroids.
Sixteen percent of those
were not involved in any
competitive sports. In another study of steroid use
among male high school seniors, 38 percent reported
beginning anabolic steroid
use at age 15 or less.
Naturally, few steroid
users are willing to talk openly. Among
those who do admit to using steroids, few
will accurately report the amounts,
strengths and combinations taken. Anecdotal reports suggest athletes take doses
that are from four to more than 100 times
greater than those approved in therapeutic treatment. In fact, noted Kraemer, an
underground subculture exists to share
information on experimental combinations and strengths of different steroids.
"Stacking," the taking of multiple steroids at once, is common.
Eighty-five percent of these drugs are
acquired from pharmacists, doctors and
veterinarians. The remainder are mailordered black market drugs, smuggled,
stolen or secretly manufactured products.

M ere scare tactics in

the media are unlikely to discourage

athletes from pursuing a competitive
edge with hormones. Instead, the

negative publicity surrounding steroids

undermines their legitimate applica,

tions and impedes scientific study.
...................................................................................

WINTER 1991

rivatives of the male hormone testosterone and are FDA-approved for treating a
small number of diseases. Human growth
hormone, somatotropin, comes from the
pituitary gland and is sometimes prescribed for children who are not growing
properly. But athletes use the substances
more than doctors do: to promote muscle
growth, to improve athletic performance,
and to prevent or speed recovery from
injury.
Reportedly, the first use of anabolic
steroids occurred during World War II,
when they were given to German troops
to increase strength and aggressiveness.
Based on anecdotal reports, steroids were
first used in athletics by the Russians in
1954, Friedl noted.
Since then, the use of these drugs has

BUFFALO PHYSICIAN AND BIOMEDICAL SCIENTIST

�"In a controlled research setting,
there's no way to study the superhigh
doses these athletes are taking," says
Kraemer. "It is simply not bioethical to
administer the drugs in such massive
doses." Hence, most of the information
on the health risks of anabolic steroids
comes from the treatment of patients
who have taken comparatively smaller
therapeutic doses, or from the observations of sports physicians.
Friedl noted that one important area
that needs more research is steroids' effect on the prostate gland. Because the
prostate gland is a target for
steroids, researchers suspect
that repeated use might cause
enlargement of the gland or
even cancer. He sees many
parallels between men's use
of steroids and women's use
of the contraceptive pill and
predicts that it will take a
long time for all of the effects
of steroids to emerge.
Not much is known about
the effects of steroids on
musculature and skeletal
muscle growth. However, it
is suspected that prepubescent children and adolescents
who take steroids may be in
\..l,~.
danger of stunting their
growth.
There are some effects that are more
well documented, Friedl said. Heavy users face an imbalance in high- and lowdensity lipoproteins, which may promote
arteriosclerosis and heart disease. There
have been everal case reports of strokes
that seem associated with steroids. Orally
administered steroids have been implicated in the development of benign tumors and blood-filled cysts of the liver.
Reproductive function and sex characteristics are affected. Males may suffer
from atrophy of the testes, low sperm
count, and increased libido. These effects
may gradually reverse when the drugs are
stopped. However, gynecomastia, the
enlargement of the breasts, may not. (To
rid themselves of this feminizing effect,

some body builders resort to surgical
mastectomy, Friedl noted.)
Females may exhibit increased hair
growth on the face, enlargement of the
clitoris, deepening of the voice, and loss
of menstruation. Acne in users of both
sexes is common.
The use of human growth hormone is
less prevalent than anabolic steroids,
partly because it is less available on the
black market. In adults, it causes
acromegaly, a condition characterized by
enlargement of the hands, feet and face.
Another area that researchers don't

I

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know much about is the psychological
effects of steroids. Kraemer noted that
anabolic steroid users report increased
energy, greater endurance to stress and a
keener desire to compete that can lead to
habituation. However, they also report
various forms of psychoses: delusions of
grandeur, paranoia, auditory hallucinations, depression and mania. Stopping
the drugs usually brings an end to paranoia
and mania, but may increase depression
and apathy.
"There is no question that steroids
build up bodies," noted Kraemer, "but at
what price? The young men and women
taking these drugs don't appreciate the
serious health risks they're taking, not the
least of which is potential psychological
damage. There hasn't been a careful ex-

perimental study in this area, and one is
badly needed. The people at this congress
are in a position to take that next step."

23

DNTIERNATDCNAIL
CON ff:IERIENCIE
RIEFlllECTSS SSIHID ff:T
ON SSIP&gt;IECDAILTY
"There's been a definite shift in the field
of psychoneuroendocrinology ,"explained
Uriel Halbreich, M.D., professor of psychiatry, research professor
of gynecology/ obstetrics, and director of
Biobehavioral Research at
UB.
Halbreich chaired the
21st Congress of the International Society of Psychone u roe ndoc r in o logy,
which wasco-sponsored by
UB. The congress brought
almost 450 scientists and
clinicians from around the
world to Buffalo last August to address the theme
ofhormonal modulation of
the brain and behavior.
Research during the
past 10 years has spotlighted new mechanisms of brain function, Halbreich said.
"We used to measure the peripheral
hormones, for example, cortisol, to learn
whatwasgoingon in the brain,"Halbreich
said. "It was thought that the brain created hormonal changes which then influenced behavior.
"But in the early 1980s we discovered
receptors for hormones actually in the
brain. Now we also study how the hormones, themselves, affect the brain and
cause changes in behavior."
This exciting shift has advanced the
management of mood disorders. In
studying this new mechanism of brain
function and dysfunction, better drugs
are being developed, along with more
effective treatments.

•

WINTER I99I
BUFFALO PHYSICIAN AND BIOMEDICAL SCIENTIST

�DO BAD HABITS
Sometimes, but beware of the correlations

24

pidemiology helps to answer some of society's questions, but its
findings need to be closely and carefully examined.
That was the message that Saxon Graham, Ph.D., professor and
chair of the department of Social and Preventive Medicine, delivered
as the Stockton Kimball Lecturer at the 1990 Annual Faculty Meeting
last spring.

y

Graham is an epidemiologist who received the 1990 Distinguished Achievement Award
of the American Society of Preventive Oncology for his pioneering research. He has
developed most of the epidemiologic methods that are currently used to investigate the
relationship between diet and cancer, and he and his group identified many of the
foods and food components that increase or decrease the risk of cancer.
Graham is the principal investigator of a $6 million, five-year study funded
by the National Cancer Institute to investigate the link
between diet and cancer.
While obviously an advocate of the usefulness of
epidemiology, Graham warned his audience to be cautious when dealing with epidemiological findings.

WI TER 1991

BUFFALO PHYSICIAN A D BIOMEDICAL SCIENTIST

�BREED DISEASE I
you make, warns epidemiologist Saxon Graham.

2S

"The most fundamental fact of epidemiology is that it is a very inexact science," he said.
Physicians should be aware of the trouble spots that could make a study suspect, Graham
explained:
Too little replication of a result.
Replication is especially important in epidemiology because this field is particularly prone
to errors in observation, Graham said.
These errors often occur in studies that rely upon reporting by patients themselves. Memories
of past exposure or behaviors are suspect and "even patients' current observations are not made
with the precise tools that clinicians and bench scientists are often able to use," Graham
explained.

e

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'Z

...

Too few subjects in the test.
"Individuals are so idiosyncratic that it is
difficult to generalize a finding to humans as a
group from only a small number of observa~
tions," he said.
The element
Of time.

(CONT.PAGE26)

W INT ER 199 1
BUFFALO PHYSICIAN AND BIOMEDICAL SCIE TIST

�(CONTINUED FROM PAGE 2S)

26

t seems obvious that a study must
allow enough time for a pathological effect to show up, but Graham
said that this is frequently forgotten.
In the case of Love Canal, for
example, Graham said, "the convincing
evidence probably will not be available for a good many years simply
because the diseases these exposures might cause have such a long
latency and such low incidence,"
When researchers do allow enough
time, it's possible to make strong conclusions. For example, "one of epidemiology's major accomplishments was to
show that cigarettes can kill people
after many decades of smoking,"
Graham said.
-{:{Lack of a "dose-response."
In other words, risks should increase
with higher dosages.
-{:{ Inconsistent results.
Several years ago, people became
concerned over a study that linked saccharine with bladder cancer in one sex.
Study after study failed to replicate that
finding. Finally, "the most definitive
study of the subject showed no relationship," Graham said.
He also warned that although animal
studies can be useful in corroborating
effects found in humans, "what is true for
animals is not necessarily so for people."
Several studies have shown a relationship between tumors and alcohol in
humans, but "so far as I know, the many
attempts to cause tumors in animals
with potable alcohol have been unsuccessful," he noted.
In a case such as this, "where there is
a strong association and many replications, I believe the prudent clinician
would base his behavior on the epidemiology" instead of on the animal
results, Graham said.
-{:{ Potential confounders.
Other factors can affect the results of
a study, and must also be taken into
account, Graham noted.
For example, lower cancer mortality
rates in the Los Alamos population
does not necessarily mean that plutonium is good for you. A better explanation for this phenomenon is that Los
Alamos residents are much more highly
educated and probably have stopped
WINTER 199 1

He warned t1uu aitnough
animal studies can~ useful
in corro"OOrating effects

found in humans, "what is
true for animals is not

necessarily so for ~ople. ''
smoking in larger numbers than the
comparison populations, Graham said.
Finally, Graham warned against
throwing out a set of studies just
because one or more members of the set
has a weak conclu ion.
An example is a study that looked at
whether exercise can help prevent a
second myocardial infarction (heart
attack), conducted by John Naughton,
M.D., dean of the medical school and
vice president for clinical affairs at UB.
Although the overall death rate and
the death rate due to cardiovascular disease both decreased after exercise, they
did so at a rate of "borderline statistical
significance."
However, Graham said that statistical
significance should not be the only criterion applied to this study.
"There has been replication of this
finding in 22 studies," Graham said,
"and the benefit of exercise under medical supervision probably outweighs any
potential for harm.
"Where there has been much replication of a given finding and all the findings are in the same direction, even
though some of them are not quite statistically significant, that finding bears consideration." Thi is especially important
when the proposed remedy isn't harmful.
UB's epidemiologist isn't the first
Graham to win fame for his theories on
food. In 1839, the Reverend Sylvester

Graham blamed red meats and refined
flours as a cause for the rampant sexuality of his day. As a result, "Great-greatuncle Sylvester," as the epidemiologist
jokingly called him, concocted his own
type of flour, which is known today as
graham flour.
The idea of fiber as a nutritive additive has come up several times in the
past century and a half. Although today
you can "taste them again for the first
time," as the slogan goes, back in 1888
you really could taste corn flakes for the
first time. That was when "Dr. John
Kellogg, also to cool the hot blood of
Americans, advocated the replacement
of white flour by whole grains and
invented something close to what we
know today as Kellogg's Corn Flakes,"
Graham said.
Fiber has been more recently advocated as a preventive measure for colorectal cancer, but "epidemiologic
research on fiber, per se, has been minimal and the results contradictory,"
Graham said.
Fats are being linked to cancer, in·
part because countries with high average dietary fat intake also have high
colon cancer mortality rates.
"But a simple correlation does not
neces arily indicate a causal relationship," Graham cautioned. He pointed
out that "a significant increase in the
stork population in two counties in
California paralleled an increase in the
birth rate in those counties."
The same nations that have a high
fat intake also tend to be highly industrialized, Graham explained, and the
increased risk could be due to the
industrialized nature of the countries,
rather than their high-fat diets.
And there are possible confounders
in the studies linking fat and cancer.
"Thus, we need to study not only fats,
but also high caloric intake, high body
mass, and high energy expenditure
through physical exercise in relation to
a number of cancers," Graham noted.
For the most part, epidemiologists can't
make precise recommendations about
diet, Graham explained. But epidemiology, through studies which are carefully
conducted and interpreted, can "suggest
clues for prevention of disease."
e
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Giving birth, rejecting a transplant:
Torrwsi sees intriguing similarities

By LAURIE WOLFE
ould birth actually be a mother's
immune system finally rejecting
the fetus as it would, say, a skin
graft? If so, what prevents rejection for
nine months, and could that factor be
useful in transplant acceptance?
These are some of the current questions that intrigue Thomas B. Tomasi,
M.D., Ph.D., director of the Roswell
Park Cancer Institute.
Known internationally for his landmark discovery of the mucosal immune
system, Tomasi was given UB's
Stockton Kimball Award in recognition
of his 25 years of research in immunology and over 30 years of teaching. He
will deliver the 1991 Stockton Kimball
Lecture at the Annual Faculty Meeting
in the spring.
In addition to his administrative
duties at Roswell Park, Tomasi is a professor of medicine and microbiology at
UB and head of the Molecular
Medicine and Immunology Division in
the UB Department of Medicine.
He maintains a busy and productive
lab that is looking into several questions on immunology, including the riddle that has always puzzled scientists:
How is it that the fetus survives inside
the maternal womb in spite of the fact
that it carries the foreign chromosomes
of the father? Tomasi may have discovered the answer while looking at a different problem.

Thomas B. Tomasi, M.D., Ph.D.

"Infants of almost all species, including humans, are born without any antibodies on their respiratory and other
mucosal tissues," said Tomasi. "Two of
our current projects stem from the initial question , 'Why are newborn animals deficient in their mucosal immunity, and could this deficiency be due to
a circulating factor?'"

Tomasi and his fellow researchers suspected that the factor circulated in the
blood . But, working with mice, it was
too difficult to get enough fetal blood to
proceed. Instead, the researchers used
amniotic fluid because it is more plentiful and contains many fetal proteins.
Sure enough, they found a substance
in the amniotic fluid that suppressed
WI TER 1991

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the immune response. This factor is
either identical to or closely related to
TGF-13 (transforming growth factorbeta.) Now that they knew what they
were looking for, they were able to go
back and identify the same factor in
fetal serum. The findings were published recently in the Journal of
Experimental Medicine.
Using molecular techniques, Tomasi's
lab has found that TGF-13 stays localized in the uterus. These discoveries led
to the next question: Could the factor
that makes babies deficient in their
mucosal immunity be the same factor
that keeps the mother's body from
rejecting her fetus?
"What we found was amazing-really
exciting," Tomasi said. "This substance
was present in the pregnant uterus and
not in the normal uterus. It appeared at
about the ninth day of a 20-day gestation period, reached a peak at 15 days,
and then fell off rapidly as birth
approached." He speculates that this
may be the mechanism by which pregnancy is allowed to persist.
"This has important implications,"
Tomasi said. "It's probably the hormones of pregnancy that are generating
this suppressive factor in the uterus. We
have found that this substance checks
the expression of certain antigens controlled by paternal genes - the antigens that would normally stimulate the
graft rejection phenomena.
"Now we're wondering if birth actually is a rejection phenomenon. We're
also wondering, if you lack enough of
this substance, does a miscarriage
occur? Up to now we could only speculate. But we're about to begin work
with an antibody that will neutralize
TGF-13, and this may give us an answer
as to whether or not TGF-13 is involved
in spontaneous abortion."
Within a year, Tomasi hopes to take

WINTER 1991

~~what

we found was amazing- really

exciting. This substance was present in the
pregnant uterus but not in the normal uterus.
It appeared at about the ninth day of a 20-day
gestation period, reached a peak at 15 days,
and then fell off rapidly as birth approached."
This may be the mechanism by which
pregnancy is allowed to persist.

this research further by seeing if TGF-13
is useful in preventing transplant rejection. Studies in his lab have already
found that if a skin graft is performed
between two incompatible st rains of
mice, and the animal is treated with
TGF-13, ordinary rejection of the graft is
suppressed.
"Naturally, this could have tremendous impact on the future of organ
transplants," notes Tomasi. "We're just
starting experiments with heart and
kidney transplants." Interesting ly, in
skin graft observations, Tomasi has
found that the addition of TGF-13 can
be stopped after a certain time without
causing subsequent rejection. So once
beyond an initial rejection stage, the
suppressive agent is no longer necessary.
"Of course, further studies have to be
made into the toxicity associated with
this naturally occurring immunosuppress ive factor," he noted.

These experiments are bui lt on
Tomas i's earlier ground-breaking work.
He fo und that mucous membranes in
the body produce antibodies that are
distinct from the antibodies found in
the bloodstream. T his mucosal immune
system provides the body with a vital
first line of defense against microorganisms that cause disease.
The mucous membranes l ine the
areas that come in con tact with the
external envi ronment wh e re fo reign
organisms can naturally and easi ly
invade - the eyes, ears, nose, mouth,
and gastro intestinal tract.
Today hundreds of scient ists a re
building on Tomasi's d iscove ry by
research ing various aspects of the
mucosal immunity mechanism, the
structure of these particular antibod ies,
how they are transported, and the
mechanisms of vacc ination.
Tomasi received his M.D., magna

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cum laude, in 1954 from the University
of Vermont. He then started working
on his Ph.D. at Rockefeller University,
where he began studies that led to his
discovery of the mucosal immune system. As a profe sor of medicine and a
research professor of microbiology at
UB from 1965 to 1973, he further
advanced his work. He left Buffalo to
become chairman of immunology at the
Mayo medical school, and returned to
Buffalo to head Roswell in 1986.
Tomasi will soon return to another
area of research that he began at Mayo:
the immunology of exercise.
A casual remark by a friend, a physician associated with the Olympic
Nordic Ski Team, was the catalyst that
sparked Tomasi's interest. At any one
time, the friend said, 20 percent of his
cross-country skiers were out of commission with upper respiratory infections, whereas downhill skiers did not
suffer the same setbacks. From his own
experience as a competitive skier,
Tomasi knew that cross-country skiing
was far more exhausting than downhill,
the equivalent of running a marathon
as opposed to the 300 meters.
Building on what he already knew
about the mucosal immune system,
Tomasi found that in athletes pushed to
the limit, there is essentially a disappearance of antibodies on the mucous
surfaces of the upper respiratory tract.
He also saw changes in the circulating
immune cells, the natural killer or "Nk
cells" that are involved in resistance to
cancer. Initially, there was a tremendous drop which then returned to a
normal level in about 12 to 24 hours.
So, in effect, severe physical stress
caused a temporary immune deficiency.
Conversely, if a person backed off on
extreme exercise and did moderate
workouts (this level was naturally different for each person), the person actually

enhanced his or her immune response.
This phenomenon could have considerable relevance in the treatment of
chronic diseases. Of special interest to
Tomasi is how physical and emotional
stress affect the immune systems of cancer victims. After surgery and radiation,
he wonders, why do node-negative
breast cancer victims have a survival
rate of 80 percent? Is there a mechanism that is damping the immune
response of the other 20 percent, and
could this be affected by stress?
Tomasi is in the process of assembling
a team of researchers to tackle these
questions, and the many more that are
sure to follow.
e

ANNUAL FACULTY MEETING
HoNoRs ToP TEACHERS
FoR 1990
he Annual Faculty Meeting held
each spring provides an opportunity for the UB medical school to
honor those who have made outstanding contributions. Honored in 1990:
Roland Anthone, M.D., and Sidney
Anthone, M.D., clinical professors of
surgery, were named recipients of the
third annual Robert S. Berkson
Memorial Award in the Art of
Medicine. The award recognizes excellence in patient care and teaching by
volunteer faculty members.
Bernard Eisenberg, M.D., clinical
associate professor of pediatrics,
received the Dean's Award for service
to the medical school and the
University and outstanding research. A
longtime volunteer faculty member,
Eisenberg is a member of the school's
admissions committee.
Evan Calkins, M.D., professor and
head of the medical school's Division of

Geriatrics/Gerontology, received a special award as founder of geriatric
medicine at UB. A plaque in his honor
that will hang in the medical school
describes Calkins as "an energetic,
imaginative leader with demonstrated
qualities of humanitarianism, compassion and a fondness of learning and giving. A true role model for the medical
leaders of the 21st century."
Louis A. and Ruth Siegel Teaching
Awards for teaching excellence were
presented in four categories. The recipients were:
Pre-clinical award: Alan Lesse,
M.D., assistant professor of pharmacology and therapeutics.
Clinical Award: Fred Luchette,
M.D., assistant professor of surgery.
Volunteer award: Thomas Westner,
M.D., clinical assistant professor of
medicine.
House staff awards: Frederick
Kohn, M.D., resident physician in
obstetrics/gynecology; Robert Erickson,
M.D., resident physician in family
medicine; Maheswar Rao, M.D., resident physician in medicine; and Karen
Drake, M.D., resident physician in
obstetrics/gynecology.
•

CASSEL TO VISIT UB AS
HARRINGTON PROFESSOR
hristine Cas el, M.D., an expert in
medical ethics and gerontology, will
visit UB on May 29 and 30 as the
second Harrington Visiting Professor.
Cassel is one of two women regents
of the American College of Physicians
and chief of the section of genera l
internal medicine at the University of
Chicago School of Medicine.
As the Harrington Visiting Professor,
she will give several talks and seminars.e
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Cooperation, not Competition
Thomas Riemenschneider strives to
unify teaching hospitals around common goal
By LOIS BAKER
agging along after his father in rural
Berea, Ohio, 50 years ago, Thomas
Riemenschneider saw firsthand the
tie between physician and community.
Those early impressions grew into a
love for medicine and a commitment to
pushing his profession beyond its traditional boundaries, a dedication that
Tom Riemenschneider, M.D., M.B.A.,
brings with him as the new associate
vice president for clinical affairs and
associate dean at UB Medical School.
"Most medical schools will tell you
their missions are teaching medical students, research, and patient care," he
said. "As far as I'm concerned, there are
four missions. That fourth mission is
relating to the community -- identifying community health care needs and
responding to those needs."
His goal here is ambitious: To develop
a unique model for delivering health
care to the community. As liaison
between the medical school and area
hosp itals, his job is to convince everyone to work together through a cooperative consortium, for the benefit of all.
That effort is already under way. The
hospitals' CEOs are meeting to discuss
common goals. Next will come meetings between medical directors and
department heads. If the effort is successful, Western New York could serve
as an example for other communities
across the nation.
WINTER 1991

"The degree of cooperation here is
unique," he said. "Out of 128 medical
schools in the country, only a few are
close to the model we're looking at here."
"The traditional model is one university hospital designated as the primary
teaching hospital for students and residents," Riemenschneider said.
"My own feeling is, that in recent
years, that traditional model has
become outmoded, in part because
there is an ivory tower around it," he
continued.
Because the traditional model never
existed here, he saw an unusual opportunity to move health care delivery and
medical education into the community.
In this approach, Riemenschneider
has the full approval of John Naughton,
M.D., dean of the medical school and
vice president for clinical affairs at UB,
who has championed a consortium for
15 years.
"Riemenschneider comes highly
regarded and is well versed in his field,"
Naughton said. "We think he is going
to do a very fine job."
Riemenschneider replaces Don
Larson, M.D., whom Naughton credits
with helping to organize the medical
school's Office of Clinical Affairs, and
with helping to implement its faculty
practice plan. Larson has returned to
teaching in the Department of Biology.
Riemenschneider earned his bachelor's

degree from Baldwin Wallace College
and his medical degree from SUNY's
Upstate Medical Center, now called the
Health Science Center at Syracuse.
Now a professor of pediatrics at UB,
he developed an interest in pediatrics as
a college student, watching his father
deliver babies. To test his commitment
to medicine, his father got him a job
emptying bed pans, where he didn't like
the work but loved the excitement of
the hospital.
At his father's urging, he took a summer job working for a cardiac surgeon.
A chance meeting with a physician
friend of his father led to a residency
and three-year pediatric cardiology fellowship at the UCLA School of
Medicine.
At UCLA, the appeal of the diversity
of practicing medicine in a university
setting was obvious.
"People had something different to
do every day," he said. He was hooked.
There he immersed himself in his
particular research interest -- adaptation of the newborn heart to extrauterine life. After completing his fellowship
and a two-year commitment as chief of
pediatric cardiology at Scott Air Force
Base in Illinois, he took his first job in
academic medicine at the University of
Utah Medical Center. He remained
three years as assistant professor in the
medical center's Pediatric Cardiology
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Tom Riemens,hneider, M.D., M.B.A., asso,iate vi'e president for dini,al affairs and asso(iate dean at UB
Medi,al s,hool.

Division, and directed the center's pediatrics honors program.
In 197 5 the University of California at
Davis offered Riemenschneider the
opportunity to become its chief of pediatric cardiology and set up a program in
his specialty. He spent the next 15 years
translating into action his ideas concerning a broader role for academic medicine.
At UC Davis he built the program
from scratch; then, to care for the needs
of the largely rural population served by
the medical center, he set up a network of
clinics stretching to the Oregon border.
In I982 he returned to his home turf

to rebuild the pediatric cardiology program at Case Western Reserve's School
of Medicine in Cleveland. During eight
years there he made two important
career decisions -- to earn an M.B.A.,
which he received from Baldwin
Wallace in 1987, and to become a fulltime medical administrator. He was
appointed associate dean of the medical
school in 1986.
At Case Western Reserve, with the
aid of a $425,000 grant from the
National Institutes of Health, he started a health education program in the
Cleveland Public Schools, using medi-

cal students as teachers. That initiative
resulted in 17 health care modules
being incorporated into the district's
curriculum.
The chance to build a better health
care system that could reach throughout Western New York and beyond was
too attractive to refuse.
"Most places across the country are
still in the old competition model," he
said. "In Buffalo the eight CEOs are
meeting in our conference rooms and
talking collaboratively about what's best
for the people of Western New York.
Now we've got to bring the medical
directors together, and encourage them
to begin to talk collaboratively."
One of Riemenschneider's major initiatives is to meet with department
chairs scattered throughout the teaching hospitals to determine where UB
medical school faculty should be placed
to best meet community needs and
to tackle specific community health
problems.
This is the kind of challenge that, for
Riemenschneider, makes life interesting.
He also enjoys spending time with his
large extended family, playing tennis and
golf, jogging, and country music. He
delights in the fact his daughter Laura
performs at Nashville's Opryland.
He also has a daughter Karen, an art
teacher, and a son Jim, a senior at
Baldwin Wallace, in business.
Riemenschneider admits he sometimes misses working with patients.
Knowing he continues to touch
patients' lives in a larger context, however, compensates for any sense of loss.
"In a way I'm still involved with
patients," he said, "but on a larger scale.
If I'm able to help organize this consortium and this system of health care,
think of all the patients I will have an
impact on by providing a better health
care environment."
•
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Dennis A. Nadler, M.D., '71
A mandate to develop a curriculum plan for the next decade

By LOIS BAKER
ennis A. Nadler, M.D., '71 looking relaxed in his shirt sleeves,
glasses dangling from a cord
around his neck, is talking with considerable passion about his work as new
associate dean for curricular and academic affairs at the UB medical school.
"I'm happy," he said. "I'm having
fun. It's interesting, and I'm accomplishing things."
If it weren't for his salt and pepper
hair, parted boyishly down the middle,
Nadler could, at 44, be mistaken for
one of the medical students he is
charged with supervising as head of
UB's medical education program. He
was appointed associate dean in January
1990, after serving in an interim capacity since the previous July.
A pediatrician with a specialty in
developmental difficulties, Nadler
comes well-suited for the job. He is personable and ea y going, with an empathy for young children that transformed
easily into an understanding and appreciation of young adults. The promise of
daily contact with students was one reason he took the job.
This enthusiasm was not lost on John
Naughton, M.D., dean of the medical
school and vice president for clinical
affairs at UB, when he was searching for
a replacement for Peter Ostrow, M.D.
Ostrow left the associate deanship to
return to teaching in the Department of
WINTER 1991

Dennis A. Nadler, M.D., '71, associate dean for curricular and academic affairs.

Pathology.
''Throughout his career, Dennis has
had a long track record of interest in
students and teaching," Naughton
said. "I think he has gotten off to a

very good start."
Nadler said he was programmed since
birth to be a physician. The son of a
would-be doctor who turned to pharmacy because he couldn't afford mediBUFFALO PHY ICIA

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cal school, Nadler avidly followed the
path his father relinquished. Medicine
appealed to him and he never gave serious thought to anything else.
A Buffalo native, Nadler earned his
bachelor's degree in psychology from
UB in 1967 and entered the UB medical school. He was headed for a career
as an ear, nose and throat specialist
until he spent the summer before his
senior year in medical school in the
pediatric outpatient clinic at Children's
Hospital of Buffalo. He decided to
become a pediatrician then and there.
"There's just something special about
children," he said, explaining his switch
of specialties. A devoted father, Nadler
spends as much time as possible with
his sons Noah, 17, Jacob, 10, and
Benjamin, 7, and his wife Susan.
After completing his internship and
residency at Children's, Nadler in 1974
accepted a position as pediatrician-inchief at the Jesse Nash Family Health
Center in Buffalo, became an attending
physician at Erie County Medical
Center (ECMC) and joined the UB
medical school's full-time faculty.
He served as director of the
Department of Pediatrics at ECMC
from 1977 to 1988, when he stepped
down to devote more time to the
University. He had been serving as
assistant dean for student affairs at the
medical school since 1985. In addition
to his current University post, Nadler is
medical director for the United
Cerebral Palsy Association, and an
attending pediatrician at ECMC and
Children's Hospital.
As the medical school's associate dean
for curricular and academic affairs,
Nadler is responsible for everything that
involves the education of medical students - from basic science and clinical
education, to evaluation of teaching
methods, to preparation of students for

"Teaching students
how to learn is
at least as
important as
teaching them
what to learn. "

residencies, even to financial aid.
He finds today's medical students
more sophisticated and better educated
than their counterparts of 20 years ago.
Sophistication aside, he asserts that
the basic motivation for becoming a
physician remains the same - a wish
to aid humanity.
"I don't think the majority of students
today gravitate to medicine because of
the money or because of the prestige. I
think they gravitate to medicine
because they want to help people.
"I came out of the '60s, and we were
going to save the world," he said. "I
think there is still a lot of that around."
Nadler relinquished the rewards of
caring daily for young patients for the
chance to influence the training of the
next generation of physicians. His mandate is to develop a curriculum plan for
the medical school for the next 10 years.
Toward that end, he has organized a
task force to review all medical education - faculty development, student
affairs, advising, and several other

areas - in addition to curriculum.
The task force will also assess the medical school's external resources, such as
the area's teaching hospitals and
health related professions.
He brings to the job a strong conviction that medical schools must change
the way they educate students.
"The curriculum has always been
very hospital-based, "Nadler said.
"When I was a medical student that
was just fine. I took care of all kinds of
fascinating and mundane problems.
"But today, people aren't admitted to
the hospital unless they are in crisis or
in some form of deteriorated condition.
So what we're getting in the hospitals is
a very skewed population of the
extremely ill and extremely old . You
can't give students a broad-based medical education anymore if you just put
them in hospitals."
Nadler favors placing students with
volunteer faculty in their offices, and
making better use of community-based
clinics and hospital ambulatory programs, in addition to using the traditional hospital setting.
He also advocates a new classroom
approach: stressing creative problem
solving over memorization.
"Teaching students how to learn is at
least as important as teaching them what
to learn," he said. "Developing problemsolving skills, clinically based basic science
education, reducing lecture time, and
placing greater emphasis on independent
learning- these are the challenges."
Nadler concedes that not everyone
views his mission in the same light.
"Some think we should continue to
be a very traditional medical school.
Some think we should become a very
innovative medical school. I suspect
there is an appropriate balance to be
struck," he said. "I hope I will be able to
find that balance."
•
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LAW vs MEDICINE
SPRING CLINICAL DAY TO
Focus ON LEGAL IssuEs
ridging the Gap Between Medicine and
Law" will be the the theme of 1991's Spring
Clinical Day and Reunion Weekend, which
will be held the weekend of May 4.
The unique Spring Clinical Day program, to
be held May 4 in the Buffalo Marrio tt, was
planned with the help of the Bar Association of
Erie County. Topics will focus on the legal issues
in the physician-patient relationship.
"Striking a Balance Between the Rights of
Patients, Doctors, and Society" will be the title of
the Stockton Kimball Lecture, to be delivered by
Sol Wachtler, the chief justice of the New York
State Court of Appeals.
The weekend opens with a reception for all
reunion classes on Friday evening, May 3, in the
Center for Tomorrow on UB's North (Amherst)
Campus. Take the advice of the reunion class
chairmen: Mark your calendars for May 4. e

"50 years - one-half
century. Let's all come to
the reunion Saturday,
May 4, 199 1."
Donald Hall '41

"Old friendships renewed,
old memories revived, reflections on life tracing back to
our days on high. Come to
our 45th reunion."
Harold Levy '46

"40 -wow! Looking forward to seeing all of you
again. We're not ge tting
older, we're getting better."
Marvin Pleskow '51

ALUMNI To HosT
RECEPTION IN BosToN
he UB Medical Alumni Association and the
Department of Neurology will host a reception in Boston, Mass. on Monday, April 22
in conjunction with the American Academy of
Neurology Meeting. All alumni/ae in the Boston
area are invited.
e

WINTER 1991

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"Long time, no see! Come
join your classmates for
our 50th reunion."
Gene Hanavan '41

"In the past 40 years, the
world, the school, medicine
have changed. Have we?
Let's get together and find
out at our reunion."
Allen Goldfarb '51

BUFFALO PHYSICIAN AND BIOMEDICAL SCIENTIST

�---------------------------~~:---------------------------

35

"35 and still alive! Please
return for classmate jive."
Edmond Gicewicz '56

"A great time with a great
bunch of people."
Harold Brody '61

"The 20th was good, let's
make the 25th great! Join
us May 3-5 to renew old
friendships and memo ries."
Jared Barlow '66

"We are looking forward
to seeing all the I5 -year
alumni and renewing
friendships."
Russell Bessette '76

"Surprise! Five years have
already slipped by. It 's
time to touch base and
catch up on what's happened. Look forward to
seeing you in May."
Jim Schlesinger '86

Carlo DeSantis '61
"20 years is a long time.
Hope we can get together
for a good time and to
renew old friendships. "

"Take a break after I 0
years! Shuffle back to
Buffalo to share in the old
and the new!"

Joel Paull '71

Bruce Cusenz '81

WINTER 1991
BUFFALO PHYSICIAN AND BIOMEDICAL SCIENTIST

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36

DAVID H. NICHOLS '47
RECEIVES DISTINGUISHED
ALUMNUS AWARD
avid H. Nichols, M.D., internationally recognized expert in the field of
reconstructive gynecologic surgery,
received the second Distinguished
Alumnus Award from the UB Medical
School and Medical Alumni Association.
A 194 7 graduate, Nichols is professor
and chair of obstetrics and gynecology
at Brown University.
A lecturer in obstetrics and gynecology
at Tufts University School of Medicine,
he also is obstetrician and gynecologistin-chief at Women &amp; Infants Hospital of
Rhode Island, Providence, and surgeonin-chief in the Department of
Gynecology and Obstetrics at Rhode
Island Hospital, Providence.
Nichols served on the faculty of the
UB medical school from 1954 to 1980
before joining the faculty of Brown
University. He was head of the
Department of Obstetrics and
Gynecology at The Buffalo General
Hospital from 197 5 to 1980, chief of
the Department of Obstetrics and
Gynecology at Sisters Hospital from
1971 to 1974 and associate cancer
research gynecologist at Roswell Park
Cancer Institute from 1953 to 1960.
He also was previously associated with
the old E.]. Meyer Memorial Hospital,
St. Francis Hospital, and the Veterans
Administration Medical Center.
Certified by the American Board of
Obstetrics and Gynecology, Nichols is a
fellow of the American College of
Obstetricians and Gynecologists,
American College of Surgeons, and
International College of Surgeons. He
is a past president of the Society of
Gynecologic Surgeons, Buffalo
Gynecologic and Obstetric Society, and
Erie County Unit of the American
Cancer Society.

WINTER 1991

David H. Nichols, '47

(ALL FOR NOMINATIONS
FOR ALUMNI AWARD
arch 1 is the deadline for
nominations for the third annual Distinguished Medical
Alumnus/a Award.
The award is presented to a graduate
of the UB medical school who is distinguished nationally or internationally in
the eyes of his or her peers and has
made an outstanding contribution to
medicine, the arts, or humanity.
The award will be presented at a special dinner in September.
Please forward the name of your nominee as soon as possible on the attached
postcard. Your cooperation is vital if this
is to be a true alumnus/a award.
e

DoNoRs HEAR TALE oF

UB MED
ScHooL
fOUNDER
edical professors of the early
1800s were restless folk who
moved from town to town,
noted Richard Lee, professor of
medicine and pediatrics at UB. When
the founding fathers left, the schools
often went under. Few schools founded
in that era exist today.
Buffalo is an exception because one
of the founding fathers of UB, James

Platt White, was committed to the
community and remained active here
for almost 50 years.
"James Platt White and Buffalo had a
remarkable association," Lee said. "If
anyone could claim the Buffalo medical
school as his child, it was he."
Lee spoke at the fifth annual meeting
of the James Platt White Society in
October honoring members who have
made an annual contribution of $1,000
or more. The members of the James
Platt White Society from Oct. 20, 1989
to Oct. 18, 1990 are:
Dr. Richard H. Adler
Dr. Kenneth M. Alford
Dr. Kenneth Z. Altshuler
Dr. William S. Andaloro
Mrs. Rose Bakow
Dr. &amp; Mrs. Jared Barlow
Dr. Alphonso L. Barragan
Dr. Charles D. Bauer
Dr. Eugene L. Beltrami
Dr. Richard A. Berkson
Dr. Willard H. Bernhoft
Dr. Theodore Bistany
Dr. Willard Boardman
Dr. Dennis L. Bordan
Mr. &amp; Mrs. Leroy B. Bornhauser
Dr. &amp; Mrs. Harold Brody
Dr. Robert L. Brown
Dr. August A. Bruno
Dr. Elaine M. Bukowski
Dr. &amp; Mrs. Irwin Burstein
Dr. David W. Butsch
Ms. Janet F. Butsch
Dr. John L. Butsch
Dr. &amp; Mrs. Evan Calkins
Dr. &amp; Mrs. Joseph G. Cardamone
Dr. &amp; Mrs. Joseph A. Chazan
Dr. Donald P. Copley
Dr. Daniel E. Curtin
Dr. James A. Curtin
Dr. Peter S. D' Arrigo
Dr. Roger Dayer
Dr. Thomas A. Donohue
Dr. Sterling Doubrava
Dr. Kenneth H. Eckhert
Dr. Robert Einhorn
Dr. &amp; Mrs. George M. Ellis

BUFFALO PHYSIC IAN AND BIOMEDICAL SCIENTIST

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37

Dr. &amp; Mrs. George M. Ellis
Dr. Daniel Fahey &amp; Dr. Maria Runfola
Dr. Lucille M. Farrar
Dr. Robert E. Fenzl
Dr. Donald M. Fisher
Dr. Jack C. Fisher
Dr. Grant T. Fisher
Dr. Edward Forgrave
Dr. Thomas F. Frawley
Dr. Matt A. Gajewski
Dr. Kenneth L. Gayles
Dr. John W. Gibbs Jr.
Dr. Daniel Goldberg
Dr. Seymour Grauer
Mr. Wilson Greatbatch
Dr. Thomas J. Guttuso
Mrs. Marion B. Hague
Dr. Martin E. Hale
Dr. Eugene J. Hanavan
Mr. &amp; Mrs. Edward A. Hansen
Dr. &amp; Mrs. Gerald Hardner
Dr. Thomas H. Hayden
Dr. Reid R. Heffner Jr.
Mr. John L. Hettrick
Dr. Gary Jeffery
Dr. &amp; Mrs. Kenneth L. Jewel
Dr. Stephen T. Joyce
Dr. James R. Kanski
Ms. Catherine Kresge
Dr. Marvin Z. Kurian
Dr. Vito P. Laglia
Dr. Andre Lascari
Dr. Eugene V. Leslie
Dr. Lawrence M. Lesser
Dr. &amp; Mrs. Harold J. Levy
Mrs. Ursula Lichtenstein
Dr. Jack Lippes
Dr. Hing Har Lo
Dr. Fred A. Luchette
Dr. Robert L. Malatesta
Dr. Milford C. Maloney
Dr. Don L. Maunz
Dr. Harry L. Metcalf
Dr. Merrill L. Miller
Dr. Eugene R. Mindel!
Dr. Joseph Monte
Dr. Shedrick Moore

Dr. Robert M. Moskowitz.
Dr. John D. Mountain
Dr. Arthur W. Mruczek Sr.
Dr. Richard L. Munk
Dr. Richard J. Nagel
Dr. Masao Nakandakari
Dr. Richard B. Narins
Dr. &amp; Mrs. John Naughton
Dr. Benjamin Obletz
Dr. Elizabeth Olmsted
Dr. Dean E. Orman
Dr. JohnS. Parker
Dr. Jacqueline L. Paroski
&amp; Dr. Paul A. Paroski
Dr. Margaret W. Paroski
Miss Olga E. Paroski
Dr. &amp; Mrs. Robert J. Patterson
Dr. Clayton A. Peimer
Dr. Victor L. Pellicano
Dr. James F. Phillips
Dr. Frederic D. Regan
Dr. Frank T. Riforgiato
Dr. Charles Riggio
Dr. Eugene Rivera
Dr. Richard R. Romanowski
Dr. &amp; Mrs. Charles H. Rosenberg
Dr. Albert Rowe
Miss Thelma Sanes
Dr. Arthur J. Schaefer
Dr. Robert N. Schnitzler
Dr. Joseph I. Schultz
Dr. Roy Seibel
Dr. Elizabeth Serrage
Dr. &amp; Mrs. Samuel Shatkin
Dr. John B. Sheffer
Miss Alice Simpson
Dr. Richard A. Smith
Dr. John J. Squad rita
Dr. William Sternfeld
Dr. Gerald Sufrin
Dr. Eugene M. Sullivan
Dr. Michael A. Sullivan
Dr. Syde A. Taheri
Dr. Joseph Tannenhaus
Dr. MichaelS. Taxier
Dr. JacobY. Terner
Dr. Charles S. Tirone

Dr. Anthony C. Trippi
Dr. Stanley Urban
Mrs. Victoria Van Coevering
Dr. Barbara von Schmidt
Dr. Coolidge S. Wakai
Dr. Franklin E. Waters
Dr. Paul Wierzbieniec
Dr. Gary Wilcox
Dr. Richard G. Williams
Dr. John R. Wright
Dr. Franklin Zeplowitz
Dr. &amp; Mrs. David C. Ziegler

REUNION (LASSES' GIFTS
HELP MEDICAL STUDENTS
edical students will benefit in
many ways from the generosity
of the alumni. As of Sept. 11,
the classes that marked their five-year
reunions in 1990 donated $123,211 to
the University.
Class of 1940: Scholarship in the
amount of$ 7,3 25
Class of 1945: Gift of $20,810 for
the Vincent Capraro Lectureship
Class of 1950: Scholarship in the
amount of $7,750
Class of 1955: Scholarship in the
amount of $6,700
Class of 1960: Unrestricted gift of
$43,700
Class of 1965: Unrestricted gift of
$8,975
Class of 1970: Unrestricted gift of
$9,225
Class of 1975: Unrestricted gift of
$4,925
Class of 1980: Gift of $12,251 for
the John Paroski Memorial Scholarship
Fund
Class of 1985: Scholarship in the
amount of $1,550

WI TER I991
BUFFALO PHYSICIAN AND BIOMEDICAL SCIENTIST

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}0._
J' S II ()

38

Philip Goldstein '31 ~ in memory of Or. Goldstein, an annual
memorial lectureship in hepatology and an award to a graduating
resident have been established at
Millard Fillmore Hospital. The
Goldstein Award is given annually to the graduating resident
"demonstrating the highest
degree of humanitarian qualities
in the approach to, and treatment of, patients." The lectureship and award were made possible by Kenneth Goldstein '39,
Gerald Goldstein '64, Harvey R.
Goldstein '77, Rabbi Brett
Goldstein and Mrs. N. Stiller.
Murray A. Yost '33 ~ received
a certificate and a gold medallion when he was honored with
lifetime membership/fellowship
in the American Psychiatric
As ociation.
John M. Constantine '34 ~ of
Oneonta, N.Y., retired from active
practice in November 1989.
Robert J. Krug '35 ~ writes
from Tarpon Springs, Fla., "had
a mild stroke, affecting left side,
but I still get around OK without a cane."
Bennie Mecklin '35 ~ writes
"Why no news from the class of
1935? I am still lecturing, writing and enjoy traveling." Or.
Mecklin resides at 6711
Starkeys Place, Lake Worth,
Fla. 33467.

Charles A. Bauda '42 ~ sent
an article from the Palm Beach
Post telling us that at the age of
74 he received a master's degree in

WINTER 1991

Milton Alter, 'SS

Donald W. Burkhardt '68

William K. Major '69

theology from St. Vincent de
Paul Seminary. Dr. Bauda practiced family medicine in Buffalo
for 40 years before moving to
Boynton Beach, Fla.

recurrent trokes. In I 989 he
became editor-in-chief of the
journal Neuroepidemiology.

gy at the University of Southern
Alabama.

Arthur J. Schaefer '47 ~was a
vtstttng professor at the
University of Washington
Medical School, Seattle, Wash.,
where he lectured on the pathophysiology and the surgical corrections of malpositions of the
upper and lower eyelids.

Victor Panaro '52 ~ of
Amherst, N.Y., has been elected
Councilor for the American
College of Radiology.
Milton Alter '55 ~ former chief
of neurology at the Minneapolis
Veteran's Hospital and former
chairman of neurology at Temple
University Hospital is now director of re idency training in neurology at the Medical College of
Pennsylvania. He holds an NIH
grant to study the epidemiology
of strokes and a supplemental
grant to study risk factors for

William J. Sullivan '55 ~ is a
diplomate of the American
Board of Psychiatry and
Neurology and is certified in
psychiatry and psychoanalysis.
He is now specializing in
forensic psychiatry.

Mary Ann Zavisca Bishara '59~
was appointed president of the
medical staff at St. Mary's
Hospital, Lewiston, N.Y., for
1990-1991 and continues as chief
of anesthesiology at the hospital.

Kenneth E. Bell '61 ~ was
recently named clinical professor of obstetrics and gynecology
at the University of California
at Irvine. Or. Bell is medical
director of the
Kaiser
Permanente Medical Center in
Anaheim, Calif.

F. Robert Weis Jr. '64

~

was
appointed a full professor and
director of clinical anesthesiolo-

David R. Dantzker '67 ~ is
now chairman of internal
medicine at Long Island Jewish
Medical Center and professor of
medicine at Albert Einstein
College of Medicine.
Donald W. Burkhardt '68 ~
retired from emergency medicine at Kenmore Mercy in
Buffalo and moved to Morocco.
He is living in a villa in the
foothills of the Middle Atlas
Mountains. His new address is
Villa William &amp; Ruth, 141
B.I.S. Route de Fes, Sefrou ,
Morocco.
John E. Shields Jr. '68 ~ is
medical director of the Seafield
Center, an 80-bed alcohol and
drug rehabilitation center in
Hampton Bays, N .Y. Or. Shields
was certified in addictionology
in 1988.
William K. Major '69 ~ a cardiothoracic surgeon, has been
elected president of the Medical
Society of the County of Erie.

BUFFALO PHYSIC IAN AND BIOMEDICAL SCIENTIST

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.f

S II ()

39

Edward J. Coleman '83 );&gt;completed a fellowship in thoracic and cardiovascular surgery
at UB in June and joined a
practice in Green Bay, Wis.

Melvin Pohl '76 );&gt;- is the
author of a book The Caregiver's

journey: VVhen You Love
Someone VVith AIDS, published
by Hazelden. Dr. Pohl is chief of
Clinical Services at the Pride
Institute in Minneapolis, Minn.

Russell J. Van Coevering 11'77

Russell J. Van Coevering II '77
);&gt;- is president of the New York
State Society of Obstetricians
and Gynecologists, Inc. and
serves on the board of directors of
the
Buffalo
Civil
War
Roundtable. Dr. Van Coevering
is a member of the President's
Associates of the UB Foundation
and the James Platt White
Society of the medical school.

Russell P. Massaro '70 );&gt;- relocated to Albany, N.Y., where he
is director of medical services
for the New York State Office of
Mental Health.

Cliphane W. McLeod '77 );&gt;writes, "Looking for a partner for
a busy ob/gyn service." Dr.
McCleod can be reached at 227
Topi Trail, Hinesville, Ga. 31313.

Jay A. Harolds '71 );&gt;- is chief
of radiology and the radiology
residency program of Baptist
Medical Center of Oklahoma
City and president of the
Oklahoma State Radiological
Society 1989-1990.

Richard T. Irene '79 );&gt;- of
Columbus Ohio, was recently
initiated a fellow of the
American College of Surgeons.

Donald H. Marcus '71 );&gt;- of
Sepu lveda, Ca lif., has been
elected to a three-year term on
the board of directors of the
Southern California Permanente Medical Group.
Roy M. Oswaks '71 );&gt;- continues as chief of surgery at Bayside
Hospital in Virginia Beach, Va.
Joseph A. Dunn, Ph.D. '71 );&gt;a senior research scientist at
Eastman Kodak, has started a
two-year sabbatical in the
Biotechnology Center of
Cornell University.

Robert Braco '80 );&gt;- writes,
"Completed my MPH in May
and started working for the
University of Texas School of
Public Health in Houston, looking after the health of employees
of major petrochemical companies in the Houston area. It's
great, I highly recommend it."
Jonathan C. Felsher '80 );&gt;- has
a private practice in cardiology
and is associated with the
Crozer-Chester Medical Center
and the Bryn Mawr Hospital.
He and his wife, Lisa, have two
children: Matthew, 2, and
Marisa, 9 months.

Renata Wajsman '83 );&gt;- writes,
"After working for a year as a
gastroenterologist, I am moving
on to Israel to take a full-time
position in gastroenterology in
Tel Aviv-lchilov Hospital."

Robert Braco '80

Bruce J. Cusenz '81 );&gt;-is a member of Buffalo Plastic Surgery, a
practice specializing in cosmetic
surgery as well as traumatic and
reconstructive surgery. The practice has two offices: 2800 Main
St., Buffalo and 1321 Millersport
Highway, Williamsville.
Helena Reichman '81 );&gt;-former
full-time member of the faculty
at the University of Massachusetts Medical Center and private
practitioner, is relocating to
Brandon, Fla. to join a ob/gyn
practice at Humana Hospital.

Nora Meaney-Elman '84 );&gt;- of
Amherst, N.Y., writes, "Upon
completion of residency, I am
joining the Highgate Medical
Group and practicing full-time
in family medicine."
Herbert B. Newton '84 );&gt;writes that he finished at
Memorial Sloan-Kettering
Cancer Center in June , then
became the neuro-oncologist
for Ohio State's new cancer
center in July. "Go Buckeyes!"
John Picano '84 );&gt;- completed a
neuroradiology fellowship at
Massachusetts General Hospital in
June and moved to New Hartford,
N.Y. to enter private practice. He
and his wife, Lynn, have two children, John Daniel and Cara.

Lloyd D. Stahl '81 );&gt;- of
Leawood, Kan. writes, "Jackie
and I were in New Orleans when
I was inducted as a fellow into the
American College of Cardiology.
We have three children: Michael,
8; Mara, 6, and Danny, 2. We are
enjoying life in the midwest."

Maritza Alvarado '85 );&gt;- writes
that she and her husband,
Andrew Knoll '84, moved to
Syracuse, N.Y. this summer. He
began his residency in internal
medicine and she started a fellowship in neonatology.

Manuel L. Saint Martin '82 );&gt;completed law school and psychiatric residency in Los Angeles
simultaneously! He is now conducting a joint medical and legal
consulting practice in Los
Angeles and Forest Hills, N.Y.

Timothy Wacker '85 );&gt;- of
Tonawanda, N.Y., has completed a fellowship in gastroenterology/hepatology at the University
of Pittsburgh and is looking forward to starting a private practice in the Southtowns.
WINTER 1991

BUFFALO PHYSICIAN AND BIOMEDICAL SCIENTIST

�--------------- ~~~
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~'0,
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40

Douglas J. Floccare '86
Douglas J. Floccare '86 ,_.. has
been appointed the aeromedical
director of the state med-evac
helicopter fleet operated by the
Maryland State Po li ce. Dr.
Floccare currently serves as fire
surgeon for the Baltimore
County Fire Department's
Division of Emergency Medical
Services, and co-medical director
of the paramedic education program at University of Maryland
at Baltimore County's Emergency
Health Services Department.

Clarence Durshordwe '23 ,_.. an
anesthesiologist for more than
40 years in Buffalo, died Sept.
24, 1990. He had served in the
U.S. Army during World War I.
Joseph F. Kij Sr. '27 :;;;... died July
29, 1990. Dr. Kij treated five generations of patients as he became
one of the patriarchs of Western
New York's Polish-American
community. His many community endeavors included helping to
found the former St. Rita's Home
for Children and serving on the
Lackawanna School Board. He
continued his private practice in
Lackawanna until I 988.

WINTER 1991

Ramsdell Gurney ' 29 ,_.. an
organizer of the Buffalo Medical
Group, died July 30, 1990. The
group is now composed of 70
physicians. Dr. Gurney was an
associate professor of medicine
at UB.
"He was an exceptiona l
human being," said classmate
Victor L. Cohen. "He was
thoughtful, dignified, and devoted to his wife and family and to
the art of medicine. His conduct
lent dignity to the practice of
medicine and to the associate he
so skillfully chose."
William G. Ford '31 ,_.. an
internist for almost 50 years,
died Oct. 14, 1990. He worked
as a physician for Bethlehem
Stee l and was in private practice in Buffalo. During World
War II , he served as chief of
medicine on the U.S. Army's
first hospital ship as well as the
USS Ernest Hines, a luxury
liner remodeled as a hospital
ship. He retired from private
practice in 1978.
Helen Toskov Wolfson '31 ,_..
a former Buffalo clinical pathologist, died April 10, 1990 in
Ambler, Pa. Dr. Wolfson was
the only woman in the C lass of
1931. She opened her own laboratory in 1933 and remained in
practice in Buffalo until 1974.
After retiring in 1974, she
moved to West Palm Beach,
Fla., where she lived until 1986,
when she resettled in the
Philadelphia area .
Hugh J. McGee '32:;;;... a retired
neurologist died, January 27,
1990 in jackson, Mich.
Edward Shubert '39 ,_.. died
May 18, 1990.

William D. Dugan '39 ,_.. a
retired orthopaedic surgeon, died
April 15, 1990. He practiced
medicine at Buffalo General,
Children's and Mercy hospitals
in Buffa lo and our Lady of
Victory Hospital in Lackawanna.
He was a member of the Ruffed
Grouse Society and the Buffalo
T ennis and Squash Club, where
he was a champion.
Maurice M. Maltinsky '44 ,_..
d ied Jan. 25, 1990.
Vernon G . Smith '48 :;;;... a
pathologist, died Ocr. 20, 1990.
He founded and directed
Western ew York Analytical
Laboratories 1nc., with offices
throughout Western New York.
He had also been honored with
a team of doctors for early
research in cryogenics.
Alfred Berl '49 :;;;... a psychiatrist and horsebreeder in
Bu llvi lle, N.Y., died suddenly in
Puerto Rico on May 9, 1990.
Dr. Berl was a former teaching
psychiatrist at Yale, former chief
psychiatrist of the Manhattan
House of Detention and, during
the Korean War served as chief
psychiatrist of the Far East
Command. With a partner, Dr.
Berl founded Excelsior Farms in
Bullvi ll e in 1965, and bred
many top pacing horses, including Fly Fly Solly, who earned
over $700,000 and the former
world champion pacing gelding
Magna Bird. Until the time of
his death, Dr. Berl served on the
Advisory Counsel of Camp
Blueberry Treatment Center for
Autistic Children.
Haluk Caglar '56 ,_.. assistant
professor at UB and a specialist
in gynecologic oncology, died

june 30, 1990 after a lengthy illness. He was 45.
Born in Turkey, he came to
the United States in 1971 and
attended the UB medical school
and Georgetown University
Medical School. He received
many teaching awards at UB
and wrote numerous chapters in
medical textbooks. An artist,
his paintings were exhibited in
galleries in Toronto.
David E. Pittman '64 :;;;... a
member of the James Platt
White Society and supporter of
the University at Buffalo Foundation, died on October 26, 1989.
He held a number of University
appointments, including clinical
assistant professor of Medicine
at the University of Pittsburgh
and the Medical College of
Pennsylvania. He was a senior
attending cardio logist and the
associate director of the cardiovascular laboratory at Allegheny
General Hospital and served on
the Editorial Board of the

Catheterization and Cardiovascular Diagnosis Journal and the
Journal of Angiology. He authored
56 scientific papers.
Lawrence J. Emrich, Ph.D. ,_..
associate research professor in
biometry at UB and a biostatistician at the Roswell Park
Cancer Institute, died June 23,
1990. He was 35.
Emrich received his doctora l
degree from UB in 1983 and
was a consultant to the School
of Dental Medicine's Ora l
Biology Department and to the
Department of Psychiatry. At
Roswell Park, he headed the
statistical consulting and statistical computing laboratories. He
was also a statistician for the
DineSystems Co. in Buffalo.

BUFFALO PHYSICIAN AND BIOMEDICAL SCIENTIST

��~-

-

~-

-

Non-Profit O rg.
U.S. Postage

Buffalo Physician and Biomedical Scientist
State University of New York at Buffalo
3435 Main Street
Buffalo, New York 14214

PAID
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Permit No. 3ll

Address Correction Requested

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ABBOTT LI3RARY, SERIALS DEPT.
CA. PIJS IIIAIL

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                <text>In Praise of Housecalls</text>
              </elementText>
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                <text> Making a Team for Michael</text>
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                <text> Danger in the Locker Room</text>
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                <text>Do Bad Habits Breed Disease</text>
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                <text> Medical School News</text>
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                <text> Classnotes </text>
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                <text>Copyright 1991 University at Buffalo, State University of New York </text>
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                    <text>Vol 25

Spnng1991

2

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Srnni.: 1991

II Research
II HospitalNews
On art and medicme,

page 18.

II HealingtheSpiritIn sickness, more than just the physical side needs to be addre-.;sed.

BJDaggersoftheMind:Shakespeare
andNeurology
Lance
Fogan, M.D., '65, catalogs the Bard's knowledge of
the field.

m

A Curefor Malpractice
HeadachesFull-rime SUNY

Hmpicalchap/amsare a ma/ pareof
the healthcareteam, page6.

faculty physicians and dentists form their own insurance company.

DJTheChnkalPktureRichard V Lee, M.D., on the affinity
between medicine and art.

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FromShin Splintsto HipPointersUB's new Sports
Medicine Institut e helps weekend and professional
athlete':&gt; alike.

BJCharting
theQuality
of LifeHarrington
Physicumsned a &lt;W)' to
quancihquabryof life
issues,page 24.

lecturer Alvan
Feinstein, M.D., laments the inability of basic science
to measure the qualit) of life.

m
m

Medical
School
News
Alumni

EEJ
Research

m
m
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People
MatchDay

Shakespe,art.'
on neurology,
/&gt;age 13.

Classnotes

Dand W'.Bt'ntb, M.D .
focmes chcmedicalschool
on healthcare[or the
agm(!, page26.

�----:(]}----

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2

ten by a one-year $15,689 grant from the
STUDY
TOSURVEY
HEALTH
Great Lakes Protection Fund, which will
IMPACT
OFEATING
GREATfocus on how consumption of fish from
the Great Lakes affects risk of malignant
LAKES
FISH
and benign thyroid disease.
B researchers chis spring will survey
30,000 New York State anglers anJ
their spouses in the largest study
ever conducted on the health impact of
caring fish from the Great Lakes.
The study, funded by the Great Lakes
Protection Fund, will focus on the consumption of fish from lakes Ontario and
Erie by residents of 16 counries, according
to John E. Vena, Ph.D., princi pal investigator and University at Buffalo associate
professor of social and preventive medicine.
Vena said researchers want to determine the characteristics of the population that consumes fish from the lakes,
how their perception of risk relates to
their consumption and rhe health effects
of that consumption. "There is a long
overdue need for a large populationbased survey of anglers
to establish
a cohort of fish carers,"
Vena added.
The study is funded
by a one-year $157,800grant
from the Great Lakes Protection Fund,
the United States' only multistate environmental endowment.
Vena also is the principal investigator on a second
study, underwrir-

U

Vena said the survey of anglers and
their spouseswill focuson a random sample
of anglers between rhe ages of 18 and 40
who live in the 16 counties and were
issued a fishing license in New York since
October 1990. The self-aJministered
questionnaire will be mailed in May, he
added.
The 16 counties are: Cayuga, Erie,
Genesee, Jefferson, Lewis, Livingston,
Monroe, Niagara, Oneida, Onondaga,
Ontario, Orleans, Oswego, Sc. Lawrence,
Seneca and Wayne.
Despite advisories issued by New York
State that certain species offish caught in
Lake Ontario should not be eaten or consumed not more than once a monrh,
Vena said it's estimated that at least 15
percent of anglers eat these fish as often as
once a week.
He added chat among the Great Lakes,
Lake Onrario "has a unique contaminant
profile with the highest

documented
levels
in fish of contaminants including pestipol ych lor inated biphenyls
(PCBs)
and
methyl mercury."
Vena said that
m o s t studies to dace of consumption of contaminated fish from the Great
Lakes "have been based on small, convenient samples in ocher states. For New
York Seate, there is a lot of data on how
much fish is caught, but no data on how
much is eaten . We want to know who are

the fish eaters and how much they eat and
what do they know about the advisories."
Once chose who consume the fish are
identified, Vena explained, researchers
will be able ro look at the associat ion
between past and current consumption of
contaminated fish, whether consumption
has added to their body burden of chemicals and how consumption affects their
risk for health problems.
Barbara Knuth, Ph.D., assistant professor of natural resources and policy
management at Cornell University, will
be co-investigator in the study. Also collaborating on the study will be Germaine
Buck, Ph.D., Maria Zielezny, Ph.D.,James
Marshall, Ph.D., and Jo Freudenheim,
Ph.D., all of che the medical school's
Department of Social and Preventive
Medicine.

In
the
study,
Vena's co-investigaro rs will be John M. Lore, M.D.,
professor and former chair of the UB
medical schoo l' s Department
of
Otolaryngology, and Manuel H. Castillo,
M.D., UB assistant
professor of
otolaryngology.
Their study of the consumption of contaminated fish
from the Great Lakes
as a risk factor for malignant and
benign thyroid disease will look at lifetime fish consumption from the Great
Lakes in 58 people with cancer of the
thyroid and 237 people with endemic
goiter not due to iodine deficiency and a
matched number of controls.
'This study will be one of the first to
systematically evaluate the hypothesis chat
consumption offish from the Great Lakes
is related to risk for either malignant or
benign thyroid disease," Vena said. •

- By Arrhur Page

�-

---:(]):--

--

.,. E ~ ~

3

LINK
BETWEEN
CANCER,
ELECTRIC
BLANKETS
NEEDS
MORE
STUDY

W

hile there appears cobe no general
increase in breast cancer risk
among women who have used
electric blankets for several years, there is
a higher yet not statistically significant risk
among women who use the blankets
throughout the night, according to
researchers in the UB Department of Social
and Preventive Medicine.
John E. Vena, Ph.D., and colleagues
studied 382 postmenopausal women with
breast cancer and 439 controls who were
asked about electric blanket use in the previous lO years. The UB researchers say further studies must be done co obtain an
accurate picture on the relationship
between electric blanket use and breast
cancer risk.
It has been hypothesized chat chronic exposure to electromagnetic fields
increases breast cancer risk by suppressing the normal nocturnal rise in
pineal melatonin.
•
- By Arthur Page

More than 500 scientific papers will be
presented at the meeting sponsored by the
medical school's Department of Social and
Preventive Medicine.
Graham will be honored at a reception
and banquet at 6:30 p.m.,June 11, in the
A lbright-Knox Art Gallery, Buffalo.
The symposium honoring Graham will
explore the directions chat research should
cake to define the role of diet in the etiology of cancer.
Registration is being handled by the
Office of Conferences and Special Events
at the University at Buffalo.
•
- By Arihur Page

SYMPOSIUM
TO
HONOR
SAXON
GRAHAM

A

symposium on diet in the epidemiology of cancer will highlight the
24th annual meeting of the Society
for Epidemiologic Research co be held June
11 to 14 at the BuffaloConvention Center.
The meeting will include a "Symposium
on Diec in the Epidemiology of Cancer:
Future Directions" in honor of Saxon L.
Graham, Ph.D., professor and chair of the
Department of Social and Preventive
Medicine, who will retire in May.

BUFFALOPHYSICIANAND BIOMEDICALSCIENTIST

mal imaging equipment and accompanying computer software chat result in che
simultaneous production of matching
thermal and visual images.
"The same electronics that generate the
thennal imaging data also provide the visible imaging data," he notes. "The same
optics that are used to generate the thermal imaging data are used co generate the
visual imaging data."
The computers used in today's thermal
imagingequipment interpret the body's radiation patterns in terms of temperature, producing readouts of numbers, shades of gray
or colors keyed co specific temperatures.
Hejazi notes that the image produced is
not a visual one, but a "picture" based solely
on temperatures that muse be interpreted.
Hejazi's electronic and optical equipment modifications result in simultaneous
production of thermal and visual images
that share a common perspective and size.
He said further modifications may provide
an ability co superimpose one image over
cheoch~
•

THERMAL
IMAGING
DRAWBACK
OVERCOME

A

major drawback that occurs in interpreting the results of thermal imaging has been overcome with technology developed by a researcher at UB's
medical school.
Shahram Hejazi, Ph.D., has developed
patented modifications to standard ther-

-

B)'

Arthur Page

SPRING 1991

�---------------------·ffi------------------+E

'll"

4

For most of the last l O years, the hospital's annual births hovered around the
2,400 mark. Births rose steadily over the
psychiatric expertise for patients who canlast three years, from 2,472 in 1988, to
2,706 in 1989 and ove r 3,000 last year.
nae be properly treated at the Community
Sister Angela Bontempo, president of
Meneal Health Center because of their
Sisters Hospital, attributed the dramatic
medical condition," or patients who canincrease to changing patterns in available
noc "receive adequate psychiatric care on
obstet ric services, a rise in area births, a
a regular medical floor."
The opening of the new facility increases strong OB residency teaching profile, dedco70 the number of beds operated by BuJfulo ication and hard work from nurses and
General for patients with psychiatric illness- physicians and high-profile marketing.
She noted that the hospital has been
es. The other 60 beds are located in the
working very hard over the years to
Community Mental Health Center.
•
strengthen its residency progra m. "We
have built up our residency program on
obstetrics and gyneco logy," she said,
addi ng, "we have improved our facilities
and capab ilitie s, invested in people and
let the physicians and public know about
or the first time in recent history, Sis- what we have. Obviously, we are very
proud of our obstetrica l service and are
ters of Charity Hospital del ivered
•
commi tted to its future."
3,000 babies in a calendar year. The
milestone delivery came down to the wire
as the 3,000th baby arrived on New Year's
Eve as I 990 drew to a close.

problems," he added .
SISTERSMAMMOGRAPHY
Noe said the new facility "makes it posUNITACCREDITED
BYA(R sible to integrate internal medicine and
isters Hospital' s Mammography Unit
has been accredited by the American
College of Radiology.
The unit, part of the hospital's Department of Diagnostic Imaging and located
next to its Breast Care Center of Western
New York, is one of 1,500 facilities chat
have been accredited nationally.
Requirements for the three-year accreditation include a peer review eva luation
of the facility's staff qua Iifications, equipment, quality control and quality assurance
programs, image quality and breast dose.
Mammograms are recommended by the
American College of Radiology,the American Cancer Society, the American Medical Association and nine other major medical organizations, every one to two years
in conjunction with a physical breast exam
every year for women between 40 and 49,
and every year in conjunct ion with a physical breast exam for women over 50. •

S

SISTERS
HOSPITAL
RECORDS
3,000THBIRTH
ONNEWYEAR'S
EVE

F

ROSWELL
PARK
CANCER
INSTITUTE
RECEIVES
NEWNCI
DESIGNATION
STATUS

BGHOPENS
1O-BED
MED-PSYCH
UNIT

B

uffalo General Hospital has opened
a new l 0-bed acute care medical-psych ia tric unit as part of a 47-bed
expansion approved by the New York
State Health Department.
The new unit, located on the 12th floor
of the hospital's 16-scory medical cower,
began admitting patients late lase year.
Philip C. Noe, administrator of BGH's
Community Meneal Health Center
(CMCH), said, "ll1e unit is among on ly 20
such facilities in the entire country. Currently, the Erie County Medical Center is
the only ocher upstate New York hospital
with an acute care unit dedicated to
patients who are diagnosed as having
both medical and psychiatric

R

... .

..
_,,.·

srtmm 1'191

oswell Park Cancer Institute has been
approved by the National Cancer
Advisory Board for status as a
National Cancer Institute-Des ignated
Comp rehensi ve Cancer Center.
One of the first three cancer centers co
receive the designation under a dual-level
eer review system and guidelines estab··hed injanuary 1990, Roswell wasfuvorly recommended for the comprehen·ive designation by NCI's Cancer
.;:;:::.
fi/
Support Grant peer review com•·.
mittee. Fox Chase Cance r
:
Center in Philadelphia
.)
and Yale University
...... :-':"
Comprehensive
.

�s

Cancer Center in New Haven, Connecticut, are the other two.
All three institutions had been NCI
comprehensive care centers under designated guidelines issued in the early 1970s.
"As one of the original three centers designated as comprehensive following the
passage of the National Cancer Act in
1971, it is most gratifying that we are also
one of the first centers ro receive redesignation under the new peer-review process," said Roswell direcror Thomas B.
Tomasi, M.D., Ph.D. 'The mark of'comprehensive cancer center' is one that the
Institute bears proudly."
The new guidelines required each center to be judged in new redesignation criteria, including:
• A strong core of basic laboratory
research,
• A viable mechanism for facilitating
links between basic/clinical research and
outside organizations,
• A proven record of innovative clinical
research trials,
• A significant amount of cancer prevention and control research,
• An effective research training and continuing education program,
• A wide range of cancer infonuation services for patients, health professionals and
the surrounding community and
• A substantial commitment ro community service and outreach activities, especially those directed coward underserved
populations or those with disproportionate
cancer rates.
•

CHILDREN'S
HOSPITAL
ANNOUNCES
ER
APPOINTMENTS
hildren's
Hospital
of Buffalo
has announced the appointment of
two physicians ro its Pediatric Emergency Room.

C

BUFFALO Pl IYSICIAN AND BIOMEDICAL SCIENTIST

OTOLARYNGOLOGY
RESIDENTS
RESEARCH
DAYSETFORJUNE

T

Eugene
W.Yates,M.D. PaulaMa1ur-Ellis,
M.D.

Paula Mazur-Ellis,M.D., clinical assistant
professor in the Department of Pediatrics,
and Eugene W. Yates,M.D., clinical instrucror in the Department of Pediatrics, have
been appointed attending physicians. They
will be responsible for patient care and
supervising the pediatric residents.
Mazur-Ellis received her medical degree
from the University of Pinsburgh and did
her post graduate work at Mercy Hospital
of Pittsburgh. She has had extensive training and education in various classifications
of life support. Prior to her new position,
she was an associate pediatrician in a private practice in Beaver, Pennsylvania and
a college health physician at Duquesne
University. Mazur-Ellis is a member of the
American Academy of Pediatrics and has
written articles and abstracts about intellectual development
status postHaemophilus Influenza meningitus.
Yates was an assistant attorney general
for the South Carolina's Attorney General's office prior ro obtaining his medical
degree from the University of South Carolina. He completed his pediatric residency at Richland Memorial Hospital in
Columbus, North Carolina. A member
of the American Academy of Pediatrics,
Yates is the co-author of publications on
child and adolescent psychiatry.
•

he Seventh Annual Residents
Research Day for Otolaryngology/
head and neck surgery will be held
Wednesday, June 5, from 8 a.m. to 3 p.m.
in Palmer Hall at Sisters Hospital.
The day will include presentation of
otolaryngology residents' research papers
and will feature visiting professor Guy M.
Osoff, D.M.D., M.D., Guy M. Maness professor and chairman of the Department of
Otolaryngology at Vanderbilt University
Medical Center, who will speak on "The
Role of Laser Technology in the Upper
Airway 1991."
•

SISTERS
HOSPITAL
NAMES
CHIEF
OF
DENTAL
MEDICINE
ayne C. Jarvis, D.D.S., has been
appointed
chief of dental
medicine at Sisters Hospital. He
previously was direcror of the hospital's
division of oral and maxillofacial surgery.
A graduate of the University of M ichigan and the University of Michigan
School of Dentistry, Jarvis completed his
residency in oral and maxillofacial surgery
at UB's School of Dentistry. He is a faculty
member at the Misch Institute for
Advanced Implant Dentistry, Dearborn,
Michigan, and the Implant Center of the
University of Pittsburgh School of Dentistry, as well as UB. He was recently certified and awarded diplomat status by the
American Board of Oral Implantology/
Implant Dentistry.
•

W

~PRING 1&lt;191

�6

YLOIS

ASTRAINED

PROFESSIONALS
,

: SIMON
TONG

CHAPLAINS

ARE
PART

OFTHE

HOSPITAL
TEAM

SPRING 1991

BUFFALO PHYSICIAN AND BIOMEDICAL SCIENTIST

��8

arher Richard Augusryn's first patient when he was a
chaplain-in-training threw a bedpan at him.
"I told my teacher, 'I only have one suit left,"' Father
Richard said after returning home to change."[ can't afford
this."
Father Richard returned to the hospital and to the
room to learn the reason behind the thrown bedpan. The
patient, he discovered, had just been cold by a physician
that she would need a double mastectomy. After delivering
his report, the doctor had abruptly walked out. And the
next person co enter the room a few minutes later received
the patient's wrath. She apologized; the chaplain-intraining learned he hadn't done anything wrong; she is
alive and well today.
"That's the creative edge in pastoral care," said Father
Richard relating the story years later. "You really don't know
what the agenda is going to be."
In a setting where most professional staff members have
clearly defined duties, the job of hospital chaplain is an
anomaly because it deals with the human and rhe spirimal
rather than the scientific, and consequently defies easy definition.
Local directors of pastoral care describe their work in
spiritual overtones: "the soul of the hospital" and "the heartbeat of the hospital."
Father Richard has been director of Buffalo General's
Pastoral Care Department since it was formed in 1988, and was
a volunteer chaplain for several years before char. With the
help of a cadre of volunteers, he attempts to meet the spirimal
needs of patients in that l,000-bed facility.
"Yes, you have doctors; yes, you have nurses," says Father
Richard in his tiny Buffalo General office. "You have all kinds
of fancy technical things in a hospital. But in sickness there's
more than just the technical char needs co be addressed, and
chat's the human.
"You have ro look at where people are coming from
psychologically and spiritually. You cry co put all chose areas in
sync, so the healing process becomes alive and real."
In an attempt co define what hospital chaplains do, it is
easier co state what they do not do. They do nor proselytize,
preach, or attempt co convert.
"We don't hand out rosaries," says Sister Lucille Socciarelli,
director of pastoral care at Mercy Hospital in South Buffalo. "I
can spend a whole visit and nor mention God."
"I don't have a religious mission," says the Rev. Jackie
Lewis, a Presbyterian minister and full-time chaplain at
Children's Hospital.
"We divorce ourselves from iniriaring the 'Jesus love~ me;
Yes I know; For the Bible cells me so' sort of thing, because
that's not where everyone is at," agrees Father RicharJ.
Humans have cared for the sick since they Jevelnpcd the
capacity for compassion, bur the position of professionally
trained hospital chaplain is relatively new.
As recently a~ the 1940s, ministering to the spiritual needs
of Lhe hospitalized was a job often relegated to problem
ministers anJ priests. That situation changed in 1951 when a
group of Protestant denominations began training ministers

for hospital work. The group was incorporated in 1967 as the
Association of Clinical Pastoral Education.
A similar Catholic organi:arion - the National Association of Catholic Chaplains - was incorporated in I 965.
Today most hospital chaplains have at least one year of
training and are certified by a board to practice in a hospital
setting.
Modern hospital chaplains are members of the treatment
ream. They serve the needs of the patients, the staff and their
families, rather than representing a particular congregation or
denomination.
They have access to patients' records, and as is the case at
Children's, particularly in the Intensive Care Nursery, are
encourageJ to record observations on patient charts. Chaplains serve on committees on ethics and institutional review.
They receive referrals from physicians likeanyorherspecialisr.
The main work of a hospital chaplain, however, is listening.
"If nothing else, I'm company," says Eliot Marrus, rabbi at
Temple Shaarey Zedek and a volunteer chaplain at Buffalo
General. "Most of all, people wane someone co talk co. My role
in the crnwersarion is almost negligible."
His favorite story about listening involves a visit with an
elderly woman in a wheelchair who had no family co visit her.
"She looked exceedingly frail," relates Rabbi Marrus. "She
J\UFFAL,1 PllYS!CtA:-.:.~Nil ll!OMElllC.~L '&lt;'IE.'-JT!ST

�Ina settingwheremast
professional
staff
members
havedearly

9

defined
duties
, thejob
of hospital
chaplain
is
ananomaly
because
ii
dealswiththehuman
andthespiritual
rather
thanthescientific,
and
consequently
defies
easydefinition.
Atleft, Father
Richard
Augustyn.
Atright,Rabbi
Eliot
Marrus.

sort of put out her hand, I took it rather gently, and felt this
viselike grip. She pulled me into the chair beside her and then
maneuvered her wheelchair so that I couldn't stand up. I was
her prisoner for the next 30 minutes while she gave me her
autobiography."
Rabbi Marrus's experience illustrates a basic tenet of the
chaplain training program: lee the patient sec the agenda .
'That might mean being kicked out," says Father Richard.
"That might mean listening to how the pastor of their church
has raked them over the coals for something. That might mean
being with someone who is dying and not saying anything."

Father Richard has been a chap lain for 11 years. Ac Buffalo
General he manages a staff of 10 trained volunteers. "The
national average is one chaplain for every 40 pacients,"he said.
"In light of that I shou ld have a staff of 42."
His chaplains are assigned to particular floors in order to
develop a relationship with staff and long-term patients. They
go from door-to-door regardless of denomination.
Most people receive him well, Father Richard says, but he
has been ejected from rooms on occasion. He figures the
negative reaction stems from preconceived notions about a
chap lain's purpose.

HosPITAL
CHAPLAINSWHo
PAYS?
ospital chaplains are members of the hospital staff and are paid by the hospital. In add ition, many hospitals supplement
their pastoral care staffs with trained volunteers.
These chaplains are primarily interdenominational and serve the hospital staff and their families as well as patients.
Ministers from specific congregations serve their own members as pare of their routine pastoral responsibilities.
Father Richard Augustyn, director of pastoral care at Buffalo Genera l Hospital and president of the National
Association of Catholic Chaplains, says all Buffalo-area hospitals had at least one full-time paid hospital chaplain as of
April 1, 1990.
Buffalo General established itsdepartmento nly two years ago. Since then, Erie County Medical Center has elim inated
the salary of its director of pastoral care in an effort to cue its budget. He is staying on temporarily as a volunteer .
Meanwhile, Millard Fillmore Hospital has just hired its first full-time director of pastoral care.
"In Buffalo we're swimming upstream," says Father Richard . "Throughout the country they're cutting departments. All
hospitals are feeling the crunch and we just don't know how it's going to pan out . ECMC'ssituation reflects the trend nationwide.
"The bottom line is, pastoral care needs to be an integral part of the hospital. We're on the right track. That's what keeps
us going."
•

-

BUFFALO PHYSIC IAN AN D BIOMEDICAL SCIENTIST

SPRING 1991

�"The concept of many people is that we're here 1roevangeenhance what is going on physically."
lize, to slap their hands for not being a good Christian," he says.
Chaplains at Mercy try to see all new admissions within 48
"The biggest egg to crack is to get beyond the hurt they bring
hours. Currently they are not entitled to record observations
with them concerning religion."
on patients' charts, but hope to acquire that privilege.
While hospital chaplains do not want to be seein as repre10
Sister Lucille said she is received well most of the time.
senting a particular religion, Father Richard is of ten called
"We always ask 'Is this a good rime?"'she said. "I've only been
upon for priestly duties. One of his warmest memorie s as a
tossed out of a couple of rooms.
chaplain centers around performing last rites for a dying
"Usually when people are sick, they are so vulnerable that
woman.
if anyone can help them, they grasp on to that straw."
He had just returned home from the Stratford !Festival in
She speaks of being called to visit with a 30-year-old
Ontario, where he had seen A Streetcar Named Desire. One
woman who had to have a double mastectomy; of comforting
of the play's central characters is the unstable woman of
a wife whose husband died of a heart attack after going out for
questionable character - Blanche DuBois.
a Friday night fish fry.
Father Richard was in bed when he got a call saying that a
Recently she stayed with an only child at the bedside of her
Mary DuBois was dying. "I went to her room, krnelt down,
dying mother. "The daughter just talked out loud to herself,
anointed her and went through the whole thing call ing her
and l was there," Sister Lucille said.
Blanche," he said. "Her husband came up to me
"Lots of times people tell us things they wouldn't
afterward and asked if it made a difference that her
tell anyone else. After being through something with
name was Mary, not Blanche, and I was devastated.
a patient, you can be closer than family."
Oneof thegreatest
"I got back down on my knees, and I'm apologizChildren's Hospital has had a Department of
ing and explaining to this woman, who is extremely
serviceschaplains
can Pastoral Care for at least 20 years, now headed by
thin and emaciated, why I cal led her Blanche, and al I
Father Frank T uchols.
offer is theirtime.
of a sudden she got this very wide smile on her face
Jackie Lewis, who has been a Presbyterian chaplain
- and she died.
there
for a year, recalls that she was called "Sister" by
Otherhospitalstaff
"Now I've got all these guilt feelings. I apologized
everyone, even when she was pregnant with her first
mustrush off lo
to her husband, but he put his arm around me and
child.
said 'Father, you've given me the best gift anyone
According to Rev. Lewis, a chaplain's responsianother
medical
crisis
;a
could give me. That's the first time I've seen my wife
bilities at Children's can range from providing supchaplain
canstay
smile in six month s."'
port for a woman experiencing a miscarriage, to
At Mercy Hosp ital a pastoral care department
performing a baptism in the intensive care nursery, to
behind.
has existed since 1975.Sister Lucille has directed the
tending a small child so the parents can be with an
Below
, SislerLucille. injured sibling.
full-time staff of two priests and four sisters for sil&lt;
years. The chaplains are part of what Sister Lucille
She says that she is received well more often than
Atright
, Rev. Jack
ie
calls the "holistic hea lth care team."
she would expect.
lewis andherson.
"[ believe so much in the ministry we are doing,'"'
"When I first began as a chaplain, I thought 'Boy,
she said "We try to reach people inside of themselve:s
if some stranger walked in when I was having a crisis,
- spiritually, psychologically, emotionally - to
I'm not sure how I'd feel.' But people are very receptive."

SPRING 1991

I\UFF.-\LO Pl IYSICI.-\N ANO BIOMEDICAL SCIENTIST

�say hello.
"A lot of the time I end up playing with the younger kids.
While we're playing things come out . Adolescents can be
really open and talk a lot, but some of them don't want to talk
at all."
Rev. Lewis says she loves her work. She could be speaking
for all hospital chaplains when she explains why.
"There is always a situation popping up that we hadn't dealt
with before. That stretches us all the time, and it's exciting. We
discover what we really believe about humandignicy, pain and
the ultimate value of people's lives."
•

CHAPLAIN
TRAINING
ATSISTERS
A isters Hospital currently offers the only hospital-based

Her first call as a chaplain while doing her clinical training
in the pediatric ward at Strong Memorial Hospital left a last-

'' chaplain training program in Western New York
designed for all religious affiliations.
The program at Sisters, accredited by che Association of Clinical Pastoral Education, or ACPE, took in
its first students in September 1990. Seven people
have gone through the program to dace, and six more
\ are enrolled for the summer.
\, Sister Margaret Dougherty, directorof pastoral care at
Sisters, supervises the program. Would-be students need

ing impressionconcerning che nacureof che human response

at least a year of theological background to enroll. Her

to crisis.
"The call was for a baby who had died in the intensive care
unit," she says. "When l walked into the room, the doctor was
sitting on the floor with the baby in his arms, the parents were
sitting beside him, and they were all crying.
"I walked in and told them who I was. The doctor handed
me the baby and they made space for me in their circle. I could
have fainted when he handed me the baby. I didn't expect that
kind of hospitality at that moment."
One of the greatest services chaplains can offer is their
time. Other hospital staff must rush off to another medical
crisis; a chaplain can stay behind.
Rev. Lewis tells of being with a husband whose wife was
killed instantly in an automobile accident. She mer him at the
bedside of his 18-month-old child injured in the same accident.
"At first he didn't say anything," she says. "Eventually he
started to talk about his wife, about how long they had been
married, about how the accident happened, about going to the
morgue to identify her body - a lot of derails he needed to talk
about.
"I think he knew that because of my role, I'd be comfortable hearing his pain. All I really did was spend time with him."
If there is time remaining after caring for emergencies,
Rev. Lewis visits children on the floors. Often they don't know
what to make of her.
"I'm pretty low key with them," she says. "I tell them I'm
not going to do anything to hurt them. That l just came in to

students are an ecumenical lot, representing a wide range
of experience .
"So far we have had a priest, a Lutheran seminary
student, an Episcopal deaconess, a Lutheran deaconess
and three Catholic laymen," said Sister Margaret. "This
summer we have an Assembly of God seminary student,
two Baptist seminary students and two Daughters of
Charity sisters."
Trainees receive 400 hours of instruction per unit,
with a minimum of cwo unit s required to become qualified
as a hospital chaplain. Students spend 25 percent of their
time in group work or individual supervision and the rest
of their hours visiting patients.
"Students learn about the process of illness, grief,
coping, the role of emotions in illness, interpersonal
relationships and give each ocher feedback," Sister Margaret said.
"What's really exciting to us is chat along with ministering to acute patients, we have some students interning in the methadone clinic. They are really working on
the spiritual dimensions of people in treatment. Ir's been
a good experience for them."
Chaplain training for Catholics is a lso offered
through the National Association
of Catholic
Chaplains, or NACC. A multi-denominational parishbased program certified by ACPE is offered through
Lutheran Social Services.
•

BUFFALOPHYSICIAN AND BIOMElllC -\L SCIENTIST

SPRINO 1991

11

�FIG

&lt;MIV:
SUl'OIK&gt;' l'IIOffTAI.

\

UN

IMtl!IOII
Fl'O'f f Al. GYII\/S

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1,AT(II.Al,..,.

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•

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Ii,

�Daggcern of theeMmJg
~ §kJkcespcearce
~ anJ Nce1Li1Jroliog
13

Pox and plague, double vision and dementia: Lance
Fogan,M.D. , '65, hasstudiedthemall- throughthe
eyes of William Shakespeare.&lt;JIAn award~winning
study written by the West Coast neurologistexamines
the neurologicaldisordersdescribedin the dramatist's
greatestplays.
Among "Dr. Shakespeare's" diagnoses: tremors, the neurological complications of syphilis, encephalopathy,
dementia, epilepsy, disturbances of
srage IV sleep, cerebra l hypoperfusion,
sciatica, pharyngeal abnormalities and
cranial nerve lesions.
"The plays of Shakespeare are the
greatest mirror of mankind, reflecting
all of our emotional and psychological
complexity and diversity," Fogan says.
"They give us the fullest possible picture of our nature.
"Shakespeare was not only acquainted with the signs, symptoms and
courses of diseases of the central and
peripheral nervous systems," Fogan
says, "but he also understood them
well."
Indeed, Fogan argues, "Shakespeare could have been a Renaissance
neurologist."
So careful and complete has been
Fogan's research in support of chis
contention that he has won widespread
recognition from neurologists and
Shakespeareans alike.His paper, "The
Neurology in Shakespeare," won the
American Academy of Neurology's
j

32 7

Lawrence C. McHenry Prize in the hisrory of neurology.
The study, which examines references ro neurology in32 of Shakespeare's
3 7 plays, not only impressed neurologists, but also attracted the attention of
the Los Angeles Daily News, the Washington Post, the Chicago Tribune and
KABC-TV in Los Angeles, which invited Fogan to appear on a health series.
Fogan's work has also piqued the
curiosity of the venerable Folger
Shakespeare Library in Washington,
D.C., which has expressed interest in
having him make a presentation.
"Shakespeareans from all over the
country wrote co me. Even my mother
read about it in Florida," Fogan says.
Fogan attributes the widespread
interest to the universal appeal
Shakespeare holds and the endless curiosity about his life, his sources, his works
and his influences. In the Los Angeles
area, where Fogan lives, there aregroups
of Shakespeare devotees - "geologists,
newspaper critics, lay people," Fogan
said, who meet to explore different approaches to reading him.
While Fogan is pleased with the
SPRING 1991

�14

reception to his paper, he is modest about
chinking, ideas, motivations, fears. Anhis own contribution to Shakespearean
thropology gives one a perception of how
studies. There are over 700 references to all of chose facets of a human being demedicine and psychiatry in Shakespeare's
velop. The knowledge of the body plays, Fogan says, and other researchers
biology and anatomy - is one thing; but
have gone over some of the terrain . He
in making the person accept your diagnocites studies on Shakespeare's knowledge
sis, your ideas about causes, testing and
of chest diseases, obstetrics, gerontology,
treatment, the physician needs to be able
ped iacrics,rheumatology, orolaryngology, co understand the who le person.
radiography and dentistry, plus countless
"Shakespeare and literature heighten
analyses by psychiatrists.
But Fogan's study highlights a
dimension of Shakespeare not fully
recognized before - Shakespeare's
breadth of knowledge of medicine,
the accuracy of his observations of
neurological signs, symptoms and
diseases and the appropriate use of
this knowledge co depict his characters.
"The fullness and accuracy of
Shakespeare's observations of behaviorcannot be overemphasized,"
says Fogan. Or overadmired, as the
vo lume of Fogan's mail from
Shakespeareans all over the country would seem to testify.
Fogan's interest in Shakespeare,
he expla ins, grew out of a life-time
Lonee
Fagan,
M.D.
, '65
interest in anthropology.
"When I was an undergraduate
at UB, I wanted to be broadly educated. I my awareness of certain aspects of human
knew I cou ld meet the science require- nature and help me to recognize the huments for medica l school without having manity around me, giving me a new
to major in a science. What I really wanted awareness of motivations and feelings and
to study was mankind, so I decided to helping me to perceive, absorb and share
what other people are feeling," Fogan
major in anthropology."
says.
Though a pre-med student, Fogan
Fogan became seriously interested in
found encouragement for his interests
from anthropology professors Henry Lee Shakespeare in the summer of 1977, when
Smith Jr. and David Stout. The advisor to he spent a three-month study leave in
London and was able co make weekend
pre-med students, Roger Gracwick,
thought his interest in anthropology co be visits to Stratford. Upon returning, he
a fine, if unusual, foundation for medical enrolled in a night course on Shakespeare
at the local community college - the
studies.
Looking back, Fogan values the for- College of the Canyons in Valencia,
mative liberal arts education he received California - which offered a six-year
course covering the complete plays and
::tsa UB undergraduate.
"My backgrou nd in anthropology and poetry. Fogan faithfully attended for all
linguistics served as an excellent founda- six years.
"I started to notice the double vision,
tion for me as a physician. A physician's
primary responsibility is working with the dementia, the headaches occurring so
people and trying to understand a person's frequently in the plays, and I began co

SPRl1'G 1991

takenotes,"Fogansays. ln 1987,asoucgoing president of the Los Angeles Society
of Neurology and Psychiatry, he used the
occasion of his final address to present his
research on Shakespeare. le was so well
received that he expanded it into the
prize-winning paper.
Since that presentation, the paper
has been published in The Archives of
Neurology(August 1989) and in The New
Scientist, the British equiva lent of
ScientificAmerican, under the tide
"The Neurologist of Avon" (January 1990). le was also presented for a
medical benefit at the Old Globe
Theater in San Diego (where Fogan
appeared in Renaissance costume
for the occasion), at the Institute of
Neurology of the National Hospital, Queen Square, London and for
the UB Medica l School's Department of Neurology in 1989, as part
of the annual lecture series. In 1983,
Fogan established the Edward
Fogan Lectureship/Prize in Neu;!; rology at UB in honorofhis farher.
0
~
Fogan enjoys balancing his lit&lt;
erary interests with his professional
0
responsibilities as chief of the Department of Neurology of Kaiser
Permanente Medical Center in
Panorama City, Ca lifornia, and assistant
clinical professor of neurology at the
UCLA School of Medicine . His research
interests include cluster headaches and
atypica l mycobacceria, a subject he studied for his M.P.H. (Unive rsity of Oklahoma School of Public Health, 1968). His
other research in the history of neurology
includes a study of John Cheyne, the lace
18th-century Scottish physician and one
of the founders of child neurology .
Among his many interests outside
medicine Fogan includes windsurfing and
cooking. But history and literature are his
special loves. An&lt;l what is he planning
next?
"Well, I've been reading Keats with
special attention since my last visit to
England. And then there's the Bible. I
cook a course in literature and the Bible,
and found a lot of passages of special
interest co physicians there."
•

!
i

BUFFALO PHY~ICIAN AND l\lOMEOICAL SCIENTIST

�1\le Ji cali
01seiryaf i ons
firom a
R en&amp;-issa irn.,c e l.\'lan
"Shakespeare
might have been a
neurologisc. .. he was so good at ir ...His
wonderful descriptions and delineations
in this great field of our science shows
that he had thoroughly mastered the subject in all its branches."
The preceding quote is from O.W.
Owen's 1893 medical journal "The Medicine in Shakespeare."
And while this may have been the
first word on "Shakespeare as Neurologist," certainly the current, dominant
work on neurological references in
Shakespeare belongs to UB alumnus
Lance Fogan. His award-winning paper,
"The Neurology in Shakespeare," supports Owen's recognition by noting
and discussing the various observations,
symptoms, signs and disease states of
the nervous system that appear in
Shakespea re's 37 plays and poetry.
Fogan points out that "Shakespeare's
works are replete with information and
references of particular interest co physicians."
The following has been excerpted
from Fogan's masterwork:

OntheNeurological
Complications
of Syphilis:
The "pox," referring to the venereal
disease, is mentioned in many of the works.
It became known in Europe in about the
year lSOOA.D."Timon of Athens,"which
was written sometime between 1604 and
1609, contains many references cosyphilitic symptoms. Timon shows a marked
personality change himself; he initially is
a cultured and prominent Athenian
leader. As the play proceeds his intellect
pathologically weakens and at the conclusion he is angry and violent and as his
steward Flavius cries out, "a ruinous
man .. .full of decay ... " Evolution of a
syphilitic into a pare tic clement, I offer in
pointed speculation.

I\UFF.-\LO PHY,ICl.-'.l--AND lllO MErnL AL S&lt;.'18': Tl~

Of special interest, which again emphasizes Shakespeare's power of observation, are symptoms included in Timon's
malignant tirade directed at two prostitutes. He encourages them to give them
(men) diseases "and co cause lawyer's
voices to 'crack."' Tertiary syphilis can
cause aneurysms of the ascending thoracic aorta which can compress the left
recurrent laryngeal nerve and paralyze
the left vocal chord; this clinical entity is
known as "prostitute whisper." Is this
what the Bard described, or was it gummas
of the larynx which could result in the

ninth part of a sparrow." A locus for the
foundations of memory appear in "Love's
Labor's Lost" IV,2,66: "These are begot
in the ventricle of memory, nourished in
the womb of pia macer. .." Nearly 400
years later can we be that much more
precise in "locating memory?"

OnSciatica:
One of the several references co this
affliction is offered by the "deformed and
scurrilous Greek" Thersites in "Troilus
and Cressida" V,1,25, as he includes sciaticas as one of the "rotten diseases of the

hakespeare was not only acquainted
with the signs, symptoms and courses
of diseases of the nervous system, but
he understood them well.
same symptoms? In IV,3,153:
Timo
n"...Crack the lawyer's voice,/
That he may never more false title plead/
Nor sound his quillets shrilly ..."
Tabes dorsal is is the neuropathologic
form of the disease responsible for the
lightning-like pains in the extremities,
and for impotency, which also did not
elude the great author. In IV,3,152:
Timon"...strike their sharp hins and
mar men 'sspurring ...Plague all/That your
activity may defeat and quell/The source
of all erection ..."

OnNeuroanatomy:
Shakespeare shares with us his awareness of some neuroanatomy in mentioning pia mater, which in Eli:abechan England referred not only to the membrane
covering the brain but also to the brain
itself. In "Twelfth Night" 1,5,108 the
clown says " ...whose skull Jove cram with
brains, ...one of thy kin has a most weak
pia mater." In "Troilus and Cressida"
Il,l ,66 Thersites exclaims "I have bobbed
his brain more than he has beat my
bones ...an&lt;lhis pia mater is not worth the

south" (i.e., of the southern end of the
body). Results of treatment of sciatica
must have been frequently disappointing
in Shakespeare's day, just as today, for
Thersites expounds " ...sciaticas, limekilns i' the palm (or arthritic calcifications), incurable bone-ache ..." Again, in
"Timon of Athens" IV,l,25:
Timo
n"...Thou cold sciatica,/ Cripple
our senators, that their limbs may halt as
lamely as their manners! ..."

On"Extraordinary
Measures'':
How current his ideas are, even
though they were written almost four
centuries ago. In 1988, as we minister to
our poly-intubated and venrilarory-assistcd patients in incensi,·e ca re units, as
we sometimes agoni:e over the appropriateness of our life-prolonging activities,
the Bard of Stratford-Upon-Avon admonishes us, as did Kent in "King Lear"
V,3,314:
"Vex not his ghost. 0, let him pass!
He hates him/That would upon the rack
of this tough world/ Stretch him out
longer."

•

SPRING !WI

�f.l FFALOMn, OAS A'-D Ill MEDICAL"'-""IL'-"Tl'•

�•
17

or nearly 20 years, physicians in New
York Scace have grappled with the
problem of malpractice insurance.
Now, chat is changing for full-time
faculty physicians and dentists ac
four SUNY Health Sciences Centers, thanks co an innovative new
insurance company the faculty formed
itself.
The new company, the Academic
Heal ch Professionals Insurance Association (AHPIA), is the only one of its kind
now operating in che United Scates, according to its chairman, William P.
Dillon, M.D., associate professor of gynecology-obstetrics at UB and chief of the
division of maternal/fecal medicine at
The Children's Hospital. AHPI/\ began
issuing binders in January of chis year.
Dillon, who was instrumental in
spearheading the development of the
company, noted that New York State's
malpractice insurance crisis of 1973 began the chain of events that eventually
led co the AHPIA's formation.
The early 1980s saw malpractice insurance for New York State physicians
targeted specifically at full-time University faculty. With their lower exposure
and, as state employees, indemnification
under Public Officers Law 17, full-time
facu Icymade an attractive market, Dillon
said. Indemnification under state law,
however, has not been interpreted as
such by the state's attorney general, leaving SUNY faculty physicians and dentists potentially at risk as the issue is
tested and appealed in the courts.
In 1986, as part of the United University Professions state contract negotiations, a Labor Management Committee
was formed to investigate the availability
and feasibility of self-insurance.
"The labor-management group concluded it would be to the faculty's benefit
co form our own captive insurance comBUFFALO PHYSIC IAN ANO BIOM EDICA L SCIENTI ST

licensing of AHPIA.
AnewSUNY
programformal
The company, in the short time it has
operating, is doing very well. "More
insuresfacuity been
and more faculty are joining us.
this company as safe or
physicians
&amp; dentists safer"Wethanmade
any other out there," Dillon
said. "The New York State Insurance

ACADEMIC
HEALTH
PROFESSIONALS
Department is not going to license us if
INSURANCE
ASSOCIATION
FACTS they think we're going to fail," he added
AHPIA:
• Isa reciprocal insurance company.
• Is operated by a board of d ireccors
made up of representatives of the
medical centers, dental schools and
United University Professions who
are also subscribers.
• Offers both occurrence and claimsmade policies.
• Handles all claims occurring from
private clinical practice as well as
those occurring from a faculty
member's employment.
pan y," Dilion said, noting the group based
its conclusions on two main premises:
that the insurance be available only to
full-time faculty in the practice plan and
that those faculty who joined the company would benefit in the form of lower
premiums and, in time and with the
approval of the state insurance department, the realization of dividends.
Through the efforts of a steering committee of dentists and physicians from
the four medical schools and two dental
schools and support from the deans, the
initial capital was raised. Reinsurance by
Lloyds of London, cogether with that
raised capital, met all capital obligations
under state regulations.
"After that," Dillon said, "we submitted our application for a reciprocal insurance company to the Scace Insurance
Department," in a process that would
culminate over two years later with the

In developing this company, he said "we
made sure it has belts and suspenders."
The Academic Health Professionals
Insurance Association writes both occurrence and claims-made policies. Occurrence policies are those that cover
incidents occurring during the policy year
without regard to when a claim is filed
and are available only to physicians and
dentists currently holding them with their
present company.
Claims-made policiescoveronly incidents that arise and are reported during
the policy year, but extend back to any
incident since the inception of the
insured's first claims-made policy (retroactive date). By law, physicians and dentiscs who now hold claims-made policies,
as well as those subscribing for the first
time in New York Seate, are required to
purchase claims-made policies.
Dillon stressed that besides the potential for dividends and the benefits offered
by self-governance, AHPlA has selected
specialist attorneys and would encourage
subscribers in the same specialty from
other SUNY sites to act as expert witnesses. Its philosophy is co work closely
with SUNY Central, the faculty union
and the state's attorney general co develop guidelines for the division of responsibility co defend and indemnify
losses.
"This is a company by and for the
faculty," Dillon said, adding, "This is
pioneering work. We're taking a problem
and responding to it."
•
SPRING 1991

�Ediwr's Note: Followingare excerptsfrom
an articleby RichardV. Lee, M.D. publishedi;ntheMay 1990Journal of Clinical
Epidemiology. Lee, a professorof pediatrics
and cwUunctprofessorof anthropology,is
basedin theDepartmentof Medicineat
The Chilclren'sHospira!of Buffalo.
n exquisite Van Gogh painting is
played at the Albright-Knox
Art Gallery in Buffalo. The 0/cl
Mill was completed in 1888,
two years before the artist's death and
over a century before the composition of
chis essay. There is nothing medical about
it; no earless, demented, bandaged or sick
people; no hint of plague fears, no angst .
Rather it is a welcoming, friendly landscape, full of warmth and color. It is about
two feet square, a cozy painting, incense,
arresting . 1am unable to walk along the
gallery corridor in which it hangs without
stopping.
Dissecting my affection for Van
Gogh':; painting, or any painting for that
matter, probably seems clinically obscure
for young modem physicians schooled in
"hard science." Van Gogh, I admit, does
appear a bit removed from biostatistics,
magnetic resonance imaging, coronary
angioplasty an&lt;l DNA probes. Aesthetic
sensibi1lity,however, ought not co be excluded from clinical medicine.
Indeed, how doctors perceive and
appreciate art is not merely significant. I
maintain that a well-developed aesthetic
sensitivity, an awareness of beauty and of
ugly, is clinically essential.
Physicians are caught not to regard
their patients as beautiful creatures, but
as creatures to be dissected, poked an&lt;l
observed with suspicion . The idea of the
human bo&lt;ly as a work of art smacks of
religion; that the manifestations of illness
might be considered aesthetic seems callous and disrespectful.
Art can be triv iali:ed. Medicine is coo
serious and too scient ific for such antics.
Medicine is too real to be contaminated

j

$PRING 1991

•►lriiiMIP
or distracted by the ethereality of arc.
Still, the mythic "art of medicine" continues to circulate and to remind us of a
more complete, perhaps humane, medicine. And medicine without aesthetic
sensibility and sensitivity is transformed
into a kind of neutral tinkering: routine,
colorless, boring.
Viewing Van Gogh is more than a
dissection: individual brush strokes, individual colors combine into a comprehensible whole. The painting reaches out,
sei:es my eye and captures my attention.
There is immediate comprehension, instantaneous intuition, active awareness.
Perhaps it is this intuitiveness that makes
physician-scientists so suspicious about
introducing notions of art in clinical activities.
Yet my comprehension of the nature
of a patient's misery is no less intuitive.
Examining a patient, looking at a painting, listening co music, share a sense of
being possessed, totally engaged, intuitively immersed in the object and the ace
of observation.
Clinical medicine and looking at a
painting unavoidably include my personal
interpretation of symbols and symptoms.
Boch activities require a storyteller patient or storyteller artist, visual intimacy,
time and me.
The clinical picture is a unique blend
of the patient and the physician: both
acting as artist, observer and viewer. The
pat ient 's description of che intensity of
pain is colored by fear and anxiety, the
hope chat this is "just something minor."
The doctor's relation of the description and clinical interpr etation is colored
by the "fit of the story;" does the pain
I\UFFALOPHY~ICIANA"l() BIO~tEL11CAL
--C:IENT!ST

�19

has more to do with ways of knowing as
opposed to ways of doing, with intuition
not with technique, with episteme, not

f

t

praxis.

match the events and the findings on
examination, is the patient asking for
relief of something other than pain?
Clinical truth, like a Van Gogh
painting, is a composite. Master physicians do more than master the craft of
medicine. They use it in waysthat inspire,
that expand our knowledge and our vision.
One connection between art and
medicine is epistemologic. Both depend
upon intuition, the nonquantitative apprehension and comprehension of beauty
and of ugliness.
Art proclaims its intuiti\'eness; modem medicine attempts to camouflage it.
Van Gogh uses blues, yellows and greens
to make a verdant, fecund sensual image.
A patient tells me ofarthralgias, allergies,
abortions, bruising and photosensitive
skin chat has malar telangiectasia and
atrophy. Even before the confirmatory
laboratory tests have been taken I can tell
her I have her clinical picture, a diagnosis.
Van Gogh's Old Mill is stunning. My
patient's lupus erythematosus is stunning.
But different artists, different patients and
different physicians can make different
pictures of identical scenes and diseases.
Our notion of disease and health is
the same. The clinical expression oflupus
erythematosus varies from patient to patient, the clinical picture is shaped by the
powers of description and observation by
patient and doctor, but we do not doubt
that there is a fundamental biologic disorder that generates the disease, the clinical
picture.
So the affinity between me and Van
Gogh, between my medicine and his art,

Academic medicine devotes
enormous amounts of energy, time
and verbiage to the praxis of
medicine: the design and statistical evaluation of experiments and
experience, the performance of
delicate surgery, obtaining and preserving anatomically precise, computer-enhanced images, the definition
and imposition of what is called "quality control." The officiously objective
burdens of utilization review and quality
assurance ask only about technique and
outcome. They do not ask about intuition
or interpretation. Compassion and comfort, beauty and joy, are not concerns of
"quality control."
More importantly, those moments of
exhilarating, humbling clinical intuition
are not concerns of medical educators
and administrators. Because it eludes
measurement by standard scientific, statistical studies, clinical intuition is nor
taught, or even talked about. We assume
it is a gift, an endowment students bring
to medicine, not something we teachers
impart to them.
Despite my lamentations, contemporary medical education works. Perfectly
adequate doctors are produced ... never
having attended a symphony concert or
strolled through an art gallery. Why bother
about Van Gogh's Old Mill or Lewis
Thomas' LateNight Thoughtson Mahler's

Ninth Symphony?
Because without them medicine is
ugly. And without intuition, and beauty
and ugliness, without art, what I do
wouldn't be medicine at all.

Reprintedwichpemiissionfrom The Journal of
Clinical Epidemiology, Volume43, RichardV.
Lee,M. D. , TheClinicalPicwre,Co/J)'righr1990,
PergamonPress, Inc.
SPRING 19'11

���sawacauliflower
earinanybody
-= I never
--- butawrestler.
Sore
shoulders
and
elbows
a.&gt;

'--'

22

cs

a.&gt;

E

common
ailments
inpitchers.
c:s are
.....
a.&gt;
-=
a.&gt;

C:S&gt;

---=
-c:s

=
-=
c:s
E

-=
C

~

"There is no place like this in Western New York," says
Edmond J.Gicewic:, M.O., of the 13,000square feet of
space in Farber Hall that houses UB's new Sports
Medicine Institute.
The innovative program on the South Campus is
designed for the specialized management and treatment of athletic injuries. A joint effort between the UB
Medical School anJ the Division of Athletics, it operates under the aegis of the Department of Orthopaedics.
Gicewic:, an assistant professor of orthopaedics at
UB and the University's team physician for 25 years,
says the lnstitute's mandate is three-fold - education,
service and research. Its benefits, he adds, will extend to
the Western New York community at large.
The Institute brings an extra dimension to the
practice of sports medicine in the region. Assembled
under one roof are all the personnel and facilities
necessary to treat athletic injuri es on the spoc: physicians experienced in sports medicine to examine and
diagnose, X-ray and casting rooms, physical therapists
to supervise recovery and $300,000 worth of rehabi Iitation equipment co help the athlete return co playing
form, including a motion laboratory, a $52,000 Biodex
machine that assesses range of motion via computer
and whirlpools for partial and whole body hydrotherapy.
It also offers the University's Athletics Division the
quicker anJ more extensive care to its athletes it will
require for the planned move m Division ].
As an educational facility, the Spores Medicine
Institute is a training ground for students in various
specialties who need experience treating athletic inju ries.
"We have family practice residents come through
so they will know how to handle these things if they are
the only physicians in a small community . We hope to
rotate our orthopaedic residents through as part of their
training. We may have some surgical residents. We will
have medical sru&lt;lenrs, nursing students, physical
therapy students, athletic trainers," Gicewic: notes,
ad&lt;ling, "Athletes sustain many ailments not seen in
general me&lt;licine. I never saw a cauliflower car in
anybody but a wrestler. Sore shoulders and elbows are
common ailments in pitchers, and there's jumper's
knee in basketba ll."
The lnstitutc's founders, which include Robert
Gillespie, M.O., chairman of UB's Deparnncnr of

Orthopaedic Su rgery, who pressed vigorous ly for the
facility, hope to set up a fellowship in sports medicine
to round out the teaching component .
Service is the broa&lt;lesr and most public of the
lnstitute's mandates. Any person injured in any sporting activity- in competition or personal recreation may come to the Institute for care. Patients are charged
a fee for service, as at any other clinic.
Although treating people who get hurt participating in sports is not the lnstitute's sole reason for existing, tending coathletic injuries is the its most imme&lt;liate mlc, and UB's athletes were the first to benefit.
HeaJ athletic trainer Mike Rielly, who is also
program coorJinator for the Institute, works with the
athletes &lt;laily. For him the Institute is a tremendous
as·er.
It provides professional care of the highest quality
immc&lt;liarely. During football season, for example, the
Institute remained open much of the weekend to rend
to high school and college players hurt during Friday
anJ Saturday games.
Time is critica l nor only for rhe athlete's comfort
but for proper assessment of an injury, Rielly says.
"If an injury is acute, the quicker it can be evaluated, the better the chance of proper diagnosis. Some
signs can be masked if the injury is a llowed to sit for an
exten&lt;led perio&lt;l."
The Institute also conducts an outreach program
for high school athletic trainers, and sponsors symposia
for high school coaches in various sports.
The research arm of the Institute will study new
ways to treat certain ailments for which current treat-

Rt.:FF:\LO PllY~ICl:\N :\N[) RIOMEnlC..\L SCIENTl~'T

�23

ment is considered inadequate, and take on other
projects. One of its most ambitious goals is to establish
an injury registry for Western New York's young players.
"Every h igh schoo l athlete who gets hurt will fill out
a rather detailed form telling how the injury occurred,
what the acti\'ity was, whether the field was wet or dry,
whether it happened on Astroturf or grass, and when
during the game it happened," notes Gicewic:. "We
will put all this information into a data bank and study
it so we can eventually draw some conclusions."
Gicew ic: is pleased with the response the Institute
has garnered so far since it opened last August. "We
are getting patients
from Barker, Medina,
Jamestown, Ellicottville.
We are seeing a lot of
people from all age groups
and all walks of life. I
think the Institute will
be really helpful to the
Western
New York
community."
•
BUFFALO PHYSICIAN AN[) BIOMEDICAL SCIENTIST

Assembled
under
oneroofareall
thepersonnel
andfacilities
necessary
lo
treatathletic
injuries
onthe
spot.

SPRING l9&lt;ll

�24

•

ua1
Alvan Feinstein
callsfor the
creation of a new
basic science.
By

Laurie

W

Wo I f e

hen patients arc diagnosed with
a disease, they want to know
how it will affect their lives. Will
they be able to work, to drive, to
parent the1rchildren?Will rhe pain stop?
When?
And patien~ aren't the only ones
looking at chose kinds of questions. In
this era of declining economic resources,
with its concomitant soaring medical
costs, economists and insurance companies are concerned with cost/risk/benefit
ratios, noted Alvan R. Feinstein, M.D.,
when he delivered the 1990 W. D.
Harrington Lecture lase October. The
distinguished professor of Yale's Department of Medicine and director of its
Clinical Epidemiology Unit noted chat if
clinicians are co offer evitlence of benefits w the quality of life of their patients
they must have a coherent way of describing, measuring and quantifying even
simple things like "being able w breathe
comfortably" or"beingable to walk without pain." A life may not have been

s rRIN l, ! &lt;NI

extended by a procedure, but perhaps
that life's quality has been measurably
improved for the patient.
"The current challenge," Feinstein
noted, "is in mensuration and quantification. We need a language for drawing fair
and relevant comparisons, for example,
for the severity of an illness, for relief, for
comfort. We must create models that fit
the observed phenomena, rather than
forcing clinical events into
models chat may not be appropriate."
Part machematic ian, part philosopher and part
provocateur,
Feinstein
is renowned
as
thoughtful critic of
the established doctrines and practices of
clinical medicine. His
capacity to "stir things
up" was admiringly
noted by James Nolan,
M.D., professor and chair of
the department of medicine, as he introduced Feinstein to an audience of UB
faculty, alumni and students.
Attending the University of Chicago,
Feinstein earned a master's degree, and,
in 1952, a medical degree. He trained in
internal medicine at Yale and the
Rockefeller Institute. After five years as a
faculty member at New York University,
Feinstein returned to Yale where he has
remained except for a two-year visiting
professorship at the 0eparcmencofClinical Epidemiology and Biostatistics at

McMaster University, Montreal, Canada.
Feinstein's lecture was peppered with
humor and insight, focusing on the inadequacy of "basic science" to assist practicing physicians in making decisions
about managing disease. He urged creative thinking to develop "an additional
basic science for observing, quantifying
and comparing clinical phenomena" to
fill that gap.
Feinstein noted that
basic science presents
two very different challenges: to explain phenomena and to intervene upon chem. The
latter is the realm of
the practicing physician, who predicts
how to manage the
phenomena .
Feinstein predicted that the clinical observations of
practicing physicians
will become more important as medical care becomes
more expensive and the competition for
research dollars increases.
While the last century has seen tremendous advances in technology and
experimental methods that benefit explication, Feinstein said, "in general, clinicians have not developed a set of basic
scientific strategies for making and eva luating managerial decisions" about the
prevention and treatment of diseases.
As a result, "controversies and doubts
regarding the optimal usage, benefits,
risks and costs of technology exist at

BUFFALO PHY~ICIAN AND BIOMEDICAL SCIENTIST

�2S

u

5

t

every level of clinical decision-making,
from the care of a newborn to the care of
the octogenarian, from the care of the
common cold to the care of a patient
with disseminating cancer."
In the past, rhe biomedical paradigm
has generally been the search for "hard
data," obtained wirh a subject or specimen that is preservable (so as ro be reexamined). The results are usually expressed in dimensional terms, and the
measurement procedures are objective
and made preferably by machine.
Absent from the literature on therapy
arc what Feinstein referreJ to as "soft
data," descriptions of human beings and
human life made by natural observation
in clinical practice. Soft data, he cautioned eloquently, have a great effect on
good clinical decision-making. They are
"the crucial harbingers of prognosis.
Without soft data we cannot achieve
scientific reducibility and identify the
people under treatment.

BUFFALO PHYSICIA1' AND BIOMEDICAL SCIENTIST

a

0

n

5

8

"Does it matter if a congestive heart
failure consists of some relatively mild
peripheral edema, or whether the patient
is gasping with pulmonary edema? Of
course, it:does . And yer congestive heart
failure, as one part of spectrum of coronary disease, is often described without
those distinctions."
In arnother example Feinstein remarked rhat cancer studies often fail to
distinguish between patients labeled "inoperable .." The category may combine
people who will not tolerate surgery and
people wlhocould tolerate it, but refuse it.
Feinstein challenged his audience to
create indices and rating scales to identify clinical phenomena and, in effect,
"harden" soft data. In need of indexing
are such phenomena as different types of
symptom.s within the spectrum of disease, rhe severity of those symptoms, rhe
chronometry of the symptoms' manifestations, rhe auxometry (rate of progression of the ailment), rhe co-morbid asso-

y

T

m

L

e

e

ciated ailments, rhe reasons for diagnostic or therapeutic decisions and the reasons for a patient's functional limitations.
While praising the value of randomized clinical trials in remedial therapy,
Feinstein stressed they are not adequate
"in an era of burgeoning technology and
unstable therapy." High costs, cumbersome logistics, lengthy study durations
and the great number of subjects required
make randomized trials impractical in
prophylactic therapy, especially where
the goal is to prevent the adverse progression of a present disease.
"It is our job as clinicians - nor rhe
mathematicians, statisticians or computer
experts - but our job to develop an
observational substitute for randomized
experimental trials in cause and effect
reasoning. If we don't do it, it won't be
done, or it will be done badly by people
who don't understand the problems." •

Sl'Rl1'G 19~1

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&lt;)

26

The Greying of Medicine
David W. Bentley, M.D. 's Mandatefor the 21st Century

D

avid W. Bentley, M.D., has set an
ambitious goal for himself as the new
head ofUB's Division of Geriatrics/
Gerontologyto help prepare the University community for the major health
issue of the 21st century - health care
for the aging.
"Geriatrics and long term care is the
name of the game in health care today,"
said Bentley. "TI1e next 25 years are going
to be focused on these two domains. The
typical health care community and university community have nor been interested in these two domains, ever."
Since assuming his position September l,
Bentley has sought to make UB an exception to that rule. One month into 1991,
he and his colleagues had already submitted four major research granc proposals
dealing with issues affecting the elderly.
Two have already been funded.
In addition to his position as profe ·sor
and head of geriatrics, Bentley also serves
as director of the University's Multidisciplinary Center on Aging, co-director of
the Westem New York Geriatric Education Center and chief of the Geriatrics
Service at Buffalo VA Medical Center. He
was recruited to increase the research
activities of a division already strong in
clinical affairs and education.
Even before moving into his offices in
Beck Hall and the VA Medical Center,
Bentley was busy convincing 19 senior faculty in several disciplines to gear their

research in progress toward problems of the
elderly and to accept postgraduate fellows
in gemmology to work along with them.
The effort culminated in a $259,200 grant
proposal cothe National Institute on Aging
which, if approved, would set the University on an ambitirn.1i;
course of incorporating
age-related research and education
throughout the University's disciplines.
Bentley came ro gerontology rather late
in his career. A graduate of the University
of Rochester Schtx)l of Medicine and Dentistry, he took his residency in internal
medicine at Vanderbilt University Hospital and did postdoctoral work in infectious diseases at the University of Illinois.
After a two-year appointment at the
University of Manitoha, Bentley returned
to Rochester in 1972 to head the infectious
tliseases unit at Monroe Community Hospital, known intemationally for its work in
geriatrics. He remained there until coming
to UB. He was abo an associate professor
of medicine at the University of Rochester's
School of Medicine and Dentistry.
Bentley became a specialist in geriatrics
"by osmosis," he said . He worked closely
with its medical director, D. Franklin
Williams, now director of the National
Institute on Aging. His expe riences at the
Rochester hospital convinced him to
change his career and hi~ research to focus
on the elderly. When the first boards for
certifica1ion in geriatrics were offered in
I 987, he took them and passed.

Bentley said the move into geriatrics was
prompted by his own inclinat ions and a
look into the future. "For anyone in healrh
care, the demographics were very clear,"
he said. "The most rapidly growing segment of the United States is 85 years of
age and older, and the population 65 and
over is also growing very rapidly. The epidemic of Alzheimer's disease, for examp le,
is much more serious, much larger and
more costly than the epidemic of AIDS."
Bentley and his sraffhave already scored
some successes in steering the University
toward the concerns of an aging population. One of his plans for the future is to
attempt codevelop a cadre of researchers
outside the Center who will apply for and
receive funding from major grant-giving
organizations such as the National Institute of Aging. "There are only a handful
of people at the University now who have
those types of awards," Bentley said.
He credited the cooperation of his colleagues across the University for the
accomplishments of the Division and the
Center so far. "The problem chat one has
in academics," he said, "is that you have
to be good in teaching, good at research,
you arc expected to beexemplary in patient
care and to be a very good administrator.
That is a very difficulr chore for the average
person. Without so much support around
me, we could nor have achieved all we
have in these few months."
•
- B)' Lois Baker

llUFF:\LO PHYSICIAN A:-.111
llll'MEl11CAL !'CIE.Vfl~

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Davidw.Bentley,M.D., (above):

...

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"The epidemicof Alzheimer'sdisease'

for example,is much moreserious,much largerand more
costlythan the epidemicof AIDS."

BL:FFALO PHYSICl.·\N ~ND BIOME[)IC.~L SCIENTIST

SPRING 1'/&lt;ll

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28

The High Expectations of
Eddie Hoover
New Surgery Chairman Plans for the Future
&lt;ldie L. Hoover, M.D., new chairman
ofUB's Department of Surgery, credits
two people with helping him get where
he is today: a college professor who sent
him on the right path and a surgeon who
inspired him to follow it.
"I didn't have any idea about becoming
a surgeon," said Hoover, a native of Charlotte, N .C. "I went to college to get away
from farming."
Hoover chose pharmacy as his major
when he enrolled at the University of
North Carolina at Chapel Hill, because
he knew what pharmacists did . A sophomore history teacher, seeing Hoover's
grades, suggested medicine instead, and
introduced him to the clean of Duke University Medical School.
"My idea of a physician was ro go somewhere where you were needed, open an
office and treat patients," sai&lt;l Hoo\'er.
"Even when I was looking into medical
schools, there were no black specialists."
But he eventua lly enrolled at Duke,
where rhe emphasis was on turning out
people who would stay at medical schools,
teach and do research. There, Hoover
lancle&lt;lby accident under the tutelage of
Paul Ebert, M.D., a dedicated surgeon who
woulJ have a lasting influence on his life.
"He operated on children's heart s,"
Htx)Versaid. "I thought that wa~the most
exciting thing a per ·on could do in life. I
decided I was going to do it if I had to beg,
borrow or steal."

E

"I get fairly immediate
gratificationfrom what
I do. A person's
appendix hurts , I take
it out. I like the
fix-it approach."
As luck would have ir, surgery suited
Hoover's personality nicely.
"I get fairly immediate gratification
from what I do," said Hoover. "A person's
appendix hurcs, I take it out; a person has
lung cancer, I cure them, rather than readjusting pills because somebody's blood
pressure is out of control. 1 like the fixit approach."
Hoover did his internship with Ebert at
Duke University Medical Center, and
when Ebert left Duke for Cornell University Medical Center, Hoover followed. He
completed his residency and thoracic
surgery training there and at MemorialSloan Kettering Cancer Institute.
He went on to hold academic appointments at SUNY-Downstate Medical Center anJ Meharry Medical College in

Nash\·ille, as well as Cornell. He has served
on the surgical staff of New York Hospital,
Kings County Hospital and State University Hospita l, all in New York City; VA
Medical Centers in Brooklyn and Murfreesboro, Tennessee; Woodhull Medical and
Mental Health Center in Brooklyn and
G.W. Hubbard Hospital in Nashville.
Hoover assumed his UB position and
was named chief of surgery at ECMC on
September I. He also is continuing his
research, which currently centers around
the role of prosraglandins in gall stone formation and hypertens ion and kidney damage in heart transplant patients.
The new head of surgery has several
goals for his department. "First, we must
continue to provide the highest quality
patient care, and make sure all the new
technology that is safe and makes sense
is available to people in Western New
York," he said.
"Second is resident education. We
must provide the kind of training programs that allow us to attract the highest
quality residents."
His third goal is to make UB preeminent
among major public universities, he said.
"We need to rum out excel lent physicians
and academicians, so we can hold our own
in the scientific field."
The drive char pressed Hoover onward
to success as a surgeon surfaces when he
speaks of his plans to move UB toward
new surgical frontiers.

BUFFALO PHYSICIAN AND BIOMEDICAL SCIENTIST

�----------------------- ~e~

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29

EddieL Hoover
, M.D.

"We need ro start doing lung transplants," Hoover said. "We have approva l
from the state but we haven't gotten it
starred . We need to move into more laser
applications in medicine. Ten years from
now, a lot of what we do in surgery will
be replaced by laser techniques."
Preparing for that inevitability, Hoover

lll.:FFALO PHYSICIAN AND BIO~!EDIC.-\L "l"IE.'1Tl!-T

has established a study group with the
physics and electrical engineering departmen ts to develop appropriate
laser
research projects. To improve the teaching
of surgery, Hoover wants to incorporate
the newest audio-\'isual techniques.
"The new equipment is so good you can
see a lot more watching a TV screen

focused on the field than by standing at
the operating table," he said. "Now, some
students may stand there for six hours and
hardly see anything.
"We're going to start that by July,"
Hoover said. "All I need is $30,000. Somehow I'll get it.
•
- B)' Lois Baker

~l'RllsG 1991

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30

UB PHYSICIANS
USENEW
PROCEDURE
ToSAVE
GEORGIA
POLICEMAN
rill wearing an eye parch to stave off
double vision, a Savannah, Georgia,
police officer thanked God and "the
doctors in Buffalo" for saving his life after
he was shot in the head pursuing a shooting suspect in early March .
G. Scan Freeman, 28, was investigating reports of domestic violence in Savannah when the shooting occurred .
Fifteen days later, Freeman was airlifted
co Buffalo to undergo an expe rimental
procedu re in which "micro-bal loons"
were placed in his internal carotid artery
to keep him from bleeding co &lt;leach.
The procedure was performed by L.
Ne lson Hopkins, M.D., chair of the Department of Neurosurgery and chief of
neurosurgery at Millard Fillmore Hospital. Hopkins use&lt;la micro-catheter co
place the silicone micro-balloons co occlude a bu llet-damaged section of
Freeman's left carotid artery.
"The bullet tore open the left caroci&lt;l
artery ... and penetrace&lt;l the upper part
of the nasal cavity, where it came co rest"
allowing blood co escape out the nose
and th roat, Hopkins said.
A clot surrounded by soft tissue
formed, temporarily closing the com
artery, but creating a potentially lifeth reatening situation.
Usually, Hopkins said, "the clot will
dissolve and the arte ry would again begin
hemo rrhaging. If chat happened, I th ink
he likely would have bled to death."
Freeman's Georgia physic ian recalled that UB neurosurgeons were using
to coronary
a technique
similar
angioplasty co prevent an&lt;l treat stroke.
T he new technique, however, uses miniaturized catheters and balloons to ac-

S

srRINU19'11

Top,G.StanFreeman
andhiswife,Nancy,lookat X·raysandangiograms
of hisskull.Bottomleft,a
leftlateralinternal
carotid
arteryangiogram
showsshrapnel
scattered
adjacent
to thetornarteryand
thebulletlodgedinthesinus.Bottomright,a lateralskullX·rayal theballoono«lusionwitharrows
marking
thethreeballoo
ns inthe internal
carotid.
commodate the finer vessels in the bra in.
In a four-hour procedure guided by
X-ray images, with Freeman totally awake,
surgeons th readed a tiny catheter through
his femoral artery to the carotid. Hopkins
then inflate&lt;l three micro-balloons one primary and two backup- to occlude
the tear. They will be left in place and
eventually will be walled off by the body.
The permanent occlus ion of the blood
supply through the carotid will not affect
Freeman, Hopkins ad&lt;le&lt;l,exp laining he
has sufficient collateral circulation. The
bullet will be left in place .
The UB team performs about 100

balloon occlusions each year at Mil lard
Fillmore Hospital, most designed to
prevent stroke and intracerebral hemorrhage from arceriovenous ma lformations
an&lt;l aneurysms. The procedure is also
used as an adjunct to surgery to de liver
chemotherapy to or tie off the blood
supply of tumors.
The procedure was developed by
Grant Hieshcmia, M.D ., professor of ra&lt;liologyat the University of Ca lifornia at
San Francisco, and lnrerventional
Therapeutics Corp. It was first used five
years ago. Nationwide, about 1,000 such
surgeries are performed each year.
•
Bl.JFF,\L,1
rllYSl&lt;:IAN
ANDRIOMEnlCAL
SCIENTIST

�IJ

"'

31

KASSIRER
TOHEAD
JOURNAL
NEWENGLAND
OFMEDICINE
erome P. Kassirer, M.D., a 1957 graduate of the University at BuffaloSchool
of Medicine and Biomedical Sciences,
has been named the new editor-in-chief
of The New EnglandJournalof Medicine.
Kassirer will take over the helm of the
journal in July, succeeding Arnold S. Reiman, M.D., who has served as edicor-inchief since 1977. He was named on Jan.
29 following an extensive worldwidesearch
by a distinguished panel of medical leaders.

J

The New EnglandJournalof Medicine,
published by the Massachusetts Medical
Society, is the oldest continuously published medical journal in the world and
is considered the nation's leading journal
of medical research and opinion.
"l am deeply honored and pleased to
accept this position," Kassirer said. "Some
of the most illustrious names in American
medicine have brought great distinction
to the pages of The Journalduring their
tenure as editor. I hope robe inspired by
their examples, and am ready co meet the
exciting challenges that lie ahead."
A specialist in nephrology and internal
medicine, Kassirer is Sara Murray Jordan
Professor of Medicine and vice chair of the
Department of Medicine at Tufts University School of Medicine, Boston, where
he has been on the faculty since 1961. He
also is associate physician-in-chief ac the
New England Medical Center, Boston.
A Buffalo native, he attended UB as an
undergraduate from I 950 co 1953, entering
its medical school following his junior year.
He received his medical degree magnacum
laude. Since 1986, he has served as a
regional member of the governing board
of the UB Medical Alumni Association.
Kassirer received several honors while
ac UB, including the Freshman Chemistry
BLFFALOPHY~ICIANANO lllOMEDIC.ALSCIE?\TIST

Jerome
P.Kassirer
, M.D.
, '57

Award in 1953 and the Bausch and Lomb
Science Award in 1953. While in medical
school, he was named co the Gibson
Anatomical Society and Alpha Omega
Alpha and in 1957 he was recipient of the

C.V. Mosby Award and the Roswell Park
Award in Surgery.
He did his internship and served as assistant resident in medicine at The Buffalo
General Hospital from 1957 to 1959.
Kassirer has received national recognition for his work on diagnostic reasoning
and therapeutic decision-making. He is
considered a national expert in many
aspects of clinical medicine, especially kidney disorders.
Board certified by the American Board
oflncernal Medicine, Kassirer is a member
of che board of governors of the American
Board oflncemal Medicine and the board
of regents of the American College of Physicians, which named him a master in 1990.
A member of the editorial board of The
New England Journal of Medicine from
1972 co 1975, Kassirer is editor-in-chief
of Ciment Therapy in Internal Medicine
(3rd edition) and co-editor of Clinical
Forum. He
ProblemSolvingand Nephrolog)'
has authored or co-authored more than
100 editorials, scientific papers, book
chapters or case studies on various aspects
of clinical medicine.
•
- ByArthur Page
About300
guestsattended
theMedical
Alumni
reception
inhonorof the
seniormedical
doss,held
12inthe
January
38thFloor
Restaurant
of the
Marine
Midland
Center.

�__________________
____ ,,,

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32

COLLINS
LECTURE
TOUCHES
ON ETHICAL
IMPLICATIONS
OF
GENETIC
RESEARCH
s researchers unravel the mysteries
of human genetic makeup, society
must start making decisions about
how chat knowle&lt;lge will he shared and
app lied.
That's the opinion of Francis S.
Collins, M.D., Ph.D., associate professor
oflncernal Medicine and Human Genetics and chief of the Division of Medical
Genetics at the Howard Hughes Medical
Institute, University of Michigan at Ann
Arbor.
Collins spoke to more than 100
physicians, researchers and others interested in genetics on March 26 at Buffalo's
Hyatt Regency Hotel. Internationally
known for his contributions to recombinant DNA technology. Collins was the
inaugural
speaker for Children's
Hospital's Rose and Al Pastor Lecture
Series.
"DNA is an elegant scheme for storing information," he said. "Every genetic
disordercan be traced tosomethingwrong
in the DNA."
Collins reiterated his work on isolating Lhe gene for ncurofibromatosb T ypc
I a severe disorder of the nerves char
affects one in every 3,000 people worldwide.
He followed that with an explanation ofhow he isolated the gene for cystic
fibrosis using a technique called "chromosome jumping" chat allows investigators co take "large steps across the vast
expanbe of a chromosome."
It is now possible rn screen for CF
carriers, who number one in 25 in this
country, he said. Carriers carry the gene

A

Francis
S. Collins
, M.D.
, Ph.D.
for CF but do not manifest the disease
themselves.
Each baby conceived by two carriers
has a 25 percent chance of having the
disease, a 50 percent chance of being a
carrier and a 25 percent chance of being
neither a carrier nor having the disease.
"Genetics is not familiar territory to
a lot of folks," he said, adding that a
pilot counseling program of 2,000 people,
such as the one undertaken by Richard
W. Erbe, M.D., professor of pediatrics at
UB, may give clues as rn how the issue
should be approached.
Collins suggests chac couples should
be screened before a pregnancy is attempted.
"The tricky part is that we have to be
really careful when we Jo ·omething like
this so that people really understand what
the information means and there are all
sorts of ways chat that information can
get confused in people's minds," he said.
"We could righc now start a screening program that would detect 85 per-

cent of CF carriers," Collins said, but
added that a program of this scope has to
be carefully planned because it affects so
many people and there aren't nearly
enough trained counselors to impart the
information.
"People who are carriers may go away
thinking that they are going to become
sick themselves. And there are concerns
about stigmatizing - that people will
feel rhey are personally defective."
Collins said he is afraid physicians
might be pressured into offering the test
if couples who have babies with CF sued
rheir physicians, claiming their doctors
were aware a test was available.
Collins said he knows of an insurance
carrier that sent a couple a letter after
they tested rn be CF carriers that implied
they would be "expected to use the information responsibly." Ir implies that if
they had a child, the company wouldn't
pay for medical expenses, he said.
'There arc areas where a lot of people
get uncomfortable, includingmc,"Collins
said. He included sex selection among
them.
"l do occasionally have people come
in co my genetic clinic for just chat reason," Collins said, "and they look very
surprised when l say I'm not going to
participate. To me, it is an affront tO all
the reason · I went into genetics ."
He quoted from a Newsweeksurvey on
"made coorder" babies chat showed chat
I percent of couples would abort if the
baby was rhe "wrong" sex; 5 percent
would abort if the fetus had a predisposition to Alzheimer's disease (even if the
onset was in old age) and 11 percent
would abort if the child were predisposed
co obesity.
"Thar's when we have to ask where to
draw the line," Collins said. "When you
are looking at selection for traits rather
than the elimination of disease.
•
- By PaulaVoe/I
I\UFFr\Ll1 PIIYSltl-\N A1'D lllt)~IEl'IL'.-\l SCIEt-:TIST

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33

Midd leton's internationally known
research has included studies of the biochemical characteristics of allergic diseases,
especially asthma and rhinitis; chemical
mediators of allergic reactions; clinical
assessment of new anti-allergic drugs, and
effects of naturally occurring plant
flavonoids on immunologic reactions. •
- ByArthur Page

MINDELL
RECEIVES
TwoHONORS
ormer Chairman of the Department
of Orthopaedics Eugene R. Mindell,
M.O., received che Distinguished Service Award from the University of Chicago Medical Alumni Association last June.
Mindell, currently professor and Director of Orthopaedic Oncology ar Buffalo
General Hospital, was also elected a vice
president of the American OrthopaeJic
A sociation at its Boston, Massachusetts
meeting the same month.
•

F

NOENAMED
TOHEAD
DEGRAFF
REHAB
UNIT

ohn E Noe, M.D., '84, has been named
medical director ofDeGraff Hospical's
new 20-bedmedical rehabilitation unit.
The unit, which opened last December,
is the first of its kind in Niagara County.
leoffers an aggressiveapproach cothe rehabilitation of patients who suffer strokes,
neuromuscular
diseases such as multiple
John
F
.
Noe
,
M.D.
,
'84
lliott Middleton, Jr., M.D., received
sclerosis,
some
spinal
cord injuries or those
the Distinguished Service AwarJ of
with
major
joint
replacements
or amputhe American Academy of Allergy and
tations,
Noe
notes.
"Rather
than
emphaImmunology at the academy's annual
si:ing
their
level
of
disability
what
meeting held in March in San Francisco.
patients
can't
do
for
themselves
we
Middleton, professor of medicine and
adopt
strategies
so
they
can
do
as
much
for
pediatrics and director of the Allergy Divithemselves
as
they
possibly
can,"
he
adds
sion in the Department of Medicine
The new unit, which occupies the ho received the award for lifelong contribupital's
entire second floor, provides incense,
tions to the academy.
high
ly
focused therapy plus coordinated,
A fellow of the American Academy of
follow-up
home and outpatient care. It
Allergy and Immunology since 1961,he has
cakes
a
multidisciplinary
team approach,
served as the academy's president, treasurer
Noc
explains,
adding
"Members
of the
and editor of its journal, TheJournalof Allerteam
include
a
physiacrist,
physical
therHe
is
a
member
of
the
editorial
ad,·isory
gy and Clinical/mmunolog)
'. He is also a
board
of
the
Journal
of
lmmunopharmacolapists, occupational therapists, speech
clinical professor of pharmacy at UB.
Director of the Allergy and Immunology ogyandClinicalAdvancesin the Trear:mem therapists, nurses, a psychologist and sometimes social workers."
of AllergicDisorders
and international adviDivision at The Buffalo General Hospital,
sory board of the Asian Journalof Allergy
The former director of the medical rehahe is a consultant in allergy at Children's
bilitation unit at Sisters of Charity Hospital
Hospital of Buffalo and Buffalo VA Med- and Immunology.He previously served on
the editorial board of the Journalof Allergy. and clinical director of inpatienc services
ical Center.
Author or co-author of more than 190 at BuffaloGeneral Hospital, Noc is cert ified
A fellow of the American College of
by the American Board of Physical
scientific articles and l 7 book chapters,
Physicians, Middleton is a diplomate of the
and Medicine and Rehabilitation and is a memAmericanBoardof InternalMedicineand the he is senior editorof Allergy:Principles
AmericanBoardof Allergyand Immunology, Practice (C.V. Mosby Co. 1988), now in ber of the American AcaJemy of Physical
Medicine and Rehabilitation.
•
its third edition.
of which he was an original director .

J

MIDDLETON
RECEIVES
DISTINGUISHED
SERVICE
AWARD

E

Ratherthanemphasi
zing
theirdisabili
ty...we adopt
strategiesso theycan do
as muchas theycan.

BUFFALO PIIYSICI:\:- .~NP lll0~1EPI&lt; AL SCIE~Tl:-T

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34

DanielM.Green
, M.D.

GREEN
TOHEAD
NATIONAL
WILMS'
TUMOR
STUDY
COMMITTEE
aniel M. Green, M.D., UB medical
school professor of pediatrics, has
been e lected chair of the National
Wilms' Tumor Study Committee.
The committee determines what combination of therapies is best for treatment
of all types and stages of Wilms' tumor, the
most common form of kidney cancer in
chi ldren. The committee's protocols are
useJ by all hospitals participating in two
national childhood cancer study groups,
the Pediatric Oncology Group and the
Ch ildren's Cancer Study Group.
An international authority on the late
effects of cancer th erapy in children,
Green is chief of the oncology section in
the Department of Pediatrics at Roswell
Park Cance r Institute and director of the
institute's Long-Term Follow-up Clin ic.

D

Board certified in pediatrics and pediatric lhematology/oncology, he has been
a member of the UB medical school
faculty since 1978. He also is directar of
the Section of Oncology in the Division
of He·matology-Oncology at Children's
Hospiical.
Green is a member of the Scientific
Committee of the International Society
of Pedliatric Oncology, Society of Pediatric
Research, American Society of Hematology and American Society of Clinical
Oncology. He has written more than 60
scienrific articles and two books on pediatric oncology.
A graduate of Massachusetts Institute
ofTechno logy,Green received his medical
degree cum laude from St . Louis University School of Medicine in 1973. He did
his residency in pediatrics at Boston
(Mass.) City Hospital and then completed
a fellowsh ip in pediatric oncology at Sidney Farber Cancer Institute, Boston; a fellowship in medicine-hematology/oncology
at Child ren's Hospital Medical Center,
Boston, and a fellowship in pediatrics at
Harvard Medical School, Boston.
•
- By Arthur Page

UB ALUMNI
ASS
,OCIATION
To
UPDATE
DIRECTORY
h,e UB Alumni Association has contracted the Bernard C. Harris Publishirng Company to produce a comprehensive alumni directary. Scheduled for
release at year en&lt;l, the d irectory will
inclu de current name, address and telephone number, class year and degree, plus
business information (ifapplicable) bound
in a library-quality e&lt;lition.
All alumni who completed an alumni
directory questionnaire mailed earlier this
year will be contacted by the Harris Com-

T

pany to verify the information and take
book ordering information.
If you prefer not to be listed in the directory, contact the A lumni Association in
writing as soon as possible.
•

ALBINI
NAMED
FULBRIGHT
SCHOLAR,
To TEACH,
Do RESEARCH
INAUSTRIA
oris Albini, M.D., professor of microbiology and research professor of
medicine at UB, has been named a
Fulbright Scholar.
Under an awar&lt;l from the Fulbright
Scholar Program, Albini, began teaching and research in the Department of
Experimental Pathology at the University
of Innsbruck in Austr ia in March. He
will collaborate with Austrian researchers
on studies of immune responses to bacterial components and lymphocyte function
in aging.
Albini is one of936 academics, professionals and independent scholars from the
Unite&lt;l States who have received awards
under the Fulbright Scholar Program to
lecture, consult or conduct research abroad
in I 990 and 1991.
A member of the faculty of the UB
School of Medicine and Biomedical Sciences since 1975,Albini was a BuswellFellow in the Department of Microbiology in
1975 and a Max Kade Fellow in thedepanmcnt in 1974. Before joining UB, he was
a clinical assistant professorat the Institute
for Genera l and Experimental Patho logy
at the University of Vienna, Austria .
A member of the medical school's
admissions committees and its M.D./Ph.D.
program, he is a member and former chair
of the University's Laboratary Animal
Care Committee and a member of the UB
Faculty Senate. He has served on the orga-

B

BU~'FALOPHYSICIAN AND BIOME()ICAL !'CIENTIST

�----

-~l----0

'

JS

nizing committee for several of the biennia l international
convocations
on
immunology sponsored by UB's Ernest
Witebsky Center for Immunology, of
which he isa member. Albini is president
of the Buffalo Collegium oflmmunology.
The author or co-author of more than
110 scientific articles, Albini isa member
of the editorial board of Immunological
Communicationsand /nr.ernationalArchives
of Allergyand AppliedImmunologyand a
fonner member of the editorial board of
Clinical and ExperimenwlImmunology.•
- B)' Arthur Page

the Hisroryof Orolaryngology,he has been
a consultant to the Gillette Corp. and the
Ministry of Public Health for the State of
Kuwait. In 1975 he served as chief of
surgery and assistant hospital director at
Yuka Hospital for Tuberculosis and Leprosy in Kalabo, Zambia.
Author or co-author of more than 65 scientific articles,Simpson isthe author of texts
on common problems,emergenciesand laser
surgeryin otolaryngology.He has conducted
extensive researchon lasersurgeryand laser
interaction with tissue to deal with tumors
and ocher disease processes.
•
- By Arthur Page

SIMPSON
NAMED
(HAIR
OFOTOLARYNGOLOGY
eorge T.Simpson, II, M.D., has been
named professor and chair of the
medical school's Department ofOtolaryngology. He will also serve as chief of
otolaryngology/head and neck surgery at
Sisters Hospital.
He previously was acting chair and associate professor in the department of otolaryngology at Boston University School
of Medicine and instructor in ocolaryngology at Tufts University School of
Medicine, Boston. He also was otolaryngologist-in-chief at Boston University
Medical Center and director in the
Department of Otolaryngology, Department of Health and Hospitals for the City
of Boston and Boston City Hospital.
Simpson is certified by the National
Board of Medical Examiners, American
Board of Otolaryngology and American
Board of Laser Surgery.
He isa founding fellow of the American
Society for Pediatric Ocolaryngology and
a fellow of the following organi:ations:
American College of Surgeons, American
Academy of Otolaryngology - Head and
Neck Surgery, American Academy of
Pediatrics, American Society for Head and

G

BUFFALOPHYSICIAN AND IIIOMEDICAL SCIENTI~

GeorgeT.Simpson,
II,M.D.

Neck Surgery, American Bronchoesophagological Association, American
Academy of Facial Plastic and Reconstructive Surgery and American Academy of
Cosmetic Surgery.
He is a 1969 graduate of Loma Linda
University, where he received his medical
degree in 1973 and a master's degree in
public health in 1975.
Simpson completed an internship in
general surgery at the University of Alabama Medical Center and residency in head
and neck surgery at the University of California at Los Angeles. He was a fellow
in pediatric otolaryngology at Boston University and Children's Hospital Medical
Center and Harvard Medical School, a
U.S. Public Health Service/Association
of American Medical Colleges Fellow in
Yugoslaviaand American Society of Anesthesiologists Fellow at the University of
Alabama Medical Center.
Former vice president and secretaryrreasurer of the International Society for

TwoALUMNIELECTED
TO
ST.JOSEPH
HOSPITAL
MEDICAL
STAFF
ichael). Gianturco, M.D., '55, has
been elected president of the medical staff of St. Joseph Hospital.
Gianturco, a board certified genera l surgeon, has been a staff physician there for
more than 27 yearsand served as vice president of the medical staff in 1989 and secretary in 1988.
Also elected as vice president was Irving
Sterman, M.D., '64.
•

M

Michael
J.Gionturco,
M.D.

srRINO 1991

�36

Match Day '9 1 saw the suspense end for
fourth-year students as they found out where
they will do their residency training.

SPRING !'I'll

BUFFALO PHYSICIAN AND BIOMEDICAL SCIENTIST

�--

----

37

Thisstereogram
of a humingbird
in
flightapproaching
a feederhaswon
severalmedals
andhonorable
in inter·
mentions
national
competi·
lions.Theoriginal
colorphotograph
S.
is byBernard
Stell, '36.

1930s
Joseph R . Saab '34 ► writes, "still
alive and looking forward to my
60th anniversary."
Bern ard S. Stell , '36 ► has won
several medals in international
photo competitions. Stereo closeups are one his specia l interests .
Information on his stereogram and
its innovative technique will be
published by the Internaciona l
Stereoscopic Union. "According
to my research, what I have
accomplished in getting these
multiple images in one picture has
not been published before in any
pare of the world." The reproduction of the stereogram containing
three hummingbirds against a
black background is really a stereo
of a single bird with rapidly beating wings on a single approach to
the feeder. Ic has been captured in
three separate positions by three
closely spaced bursts oflight from
the flash units.

Walte r Z. Schwebel ' 38 ► is still
practicing pediatrics and is direccor of the Physically Handicapped
Children's Program for Rensselaer
County, New York.

1940s
John D. Whit e '4 0 ► of Tavernier, Florida, presented a "Talking Book" project at the Mariners
Hosp ital Health Fair in January.
Frank A. P falzer ' 49 ► is retired
and now living on Amelia Island
Florida. He writes chat he is enjoying travel and several hobbies .
Ra phael S. Good '48 ► a clinical
professor of psychiatry and obstetrics and gynecology at the University of Miami Schoo l of Medicine,
is president-elect of the South
Florida Psychiatric Society. Dr.
Good is a former president of the
Miami Obstetrical and Gynecological Society .

BUFFALO PHYSICIAN ,~ND BIOMEDICAL SCIENTI ST

K e n n e th N i sw and e r ' 4 8 ►
received an award for the best anicle in 1989 from rhe magazine

Comem/)orary
ObscemcsandGynecologyfor his article, "Neurologic
Deficits on Trial: What Response."
Dr. Niswander is professor of
obstetrics and gynecology at the
University of Ca lifornia at Davis.
Law r en ce M . Ca rd e n ' 49 ►
retired on Jan. I, 1990 and is now
living in Sarasota, Fla.

1950s
Fr ed Lee '56 ► of Ann Arbor,
Michigan, was named a fellow of
the American College of Radiology.
Ge rmante L. Bonca ldo ' 5 7 ► is
direccor of the Millard Fillmore
Rhcumacology Center, Buffalo,
New York, "an out-patient facility
for rheumatology patients in a
patient satisfying consulcaci ve
atmosphere."

Th omas P. H amilt on II '5 7 ►
has been named Deputy Commander and Direccor of Medical
Education ac the Brooke Army
Medica l Center, Fort Sam Hous•
ton, Texas.
W a r r en E. Lev in so n ' 57 ►
writes, "I was elected to the Mill
Valley City Council in April 1990.
and
My book MedicalMicrobiology
Immunology was published in
August 1989." Levinson is professor of microbiology at the University of California, San Francisco.
Ga ry Co h en '58 ► has been
appointed chief of the Division of
Chi ld and Ado lescent Psychiatry
at Children's Hospital of Buffalo.
A clinical associate professor of
psychiatry and pediatrics ac UB,
Dr. Cohen previously served I0
years as acting directo r of the divi•
sion.
John T. Korn ' 58 ► "Entered
solo ob/gyn practice in Novato,
California in 1964. Mary and I
raised and educated four sons.
Having accomplished that successful career, I closed my private
practice in l 990 and am now
enjoying an interim second career
of OBG locums tenenswork. In a
year or so I willbegin concentrating full time on all my other
neglected lifetime goals, such as
aviation, sailing, scuba diving,
deep sea fishing and traveling.
Mary, being relieved of children
and household chores, enjoys her
days in commercial retailing of
ladies accessories."
John W. Kosteck i '59 ► an associate clinical professor at UB,
received certification in general
vascular surgery from che American Board of Surgery.

SPRING 1991

�-----------------------

::,,,. _:::
---------------

-- - ------

s ll

38

Law rence E. Gra ss ' 63 ► was
just elected chief of family practice
at Phoenix Baptist Hospital for a
two-year term.
John J. LaMar '63 ► is senior
attending pediatrician at the
Memor ial Hospital of Salem, New
Jersey, where he has been on staff
for 2 5 years.
John A. Schriv er '63 ► has been
appointed head of the section of
emergency medicine at Yale
University
and director
of
emergency services at Yale New
Haven Hospital.

Dorothy
C.Rasinski
, M.D., 'S9

William
E.Abramson
, M.D.'60

Do roth y C. Rasinski '5 9 ► will
be a participant in the morning
program on Spring Clinical Day in
Buffalo on May 4. An internist,
attorney, educator and author, she
recently received a special recognition award from the American
Society of Internal Medicine. TI1is
award is presented to an internist
who has made a significant contribution to the social and economic aspects of interna l
medicine. Rasinski's flair for translating dry legal accounts of malpractice suits into interesting
vignettes has made her "Legal
Briefs"column one of the best-read
pages in The lncemisi:HealrhPolicy
in Practice.She has been an editor
for the Journalof LegalMedicine,

son has a private practice in psychiatry and is senior psychiatrist
at the Sheppard Pratt Hospita l,
Towson, Maryland.

z.

Ronald J. Kallen '60 ► is direccor
ofthe Division of PediatricNephrology and Hypertension at Lutheran
General Children's Medical Center
in Park Ridge, Ill.
Robe rt L. Malat esta ' 60 ► of
Warren, New Jersey, has been
appointed associate direccor of
Drug Safety and Surveillance at
the R. W.Johnson Pharmaceutical
Research Institute.

H arold L. Metca lf '6 0 ► is vice
president of the American AcadeLegalAspectsof MedicalPractice, my of Family Physicians FoundaClinicalOiabeies,
Journalof Clinical tion with headquarters in Kansas
City, Mo.
EihicsandHospical
EthicsCommit-

Willi am E. A br a mso n ' 60 ►
"attended my first class reunion
and Spring C linical Day in April
1990 and had a ball. Will :me nd
in 1995, God willing." Abram-

:-PRINUl'l'll

Bert A. Lies, Jr. ' 64 ► of Santa
Fe, New Mexico, continues to
practice orthopaedic surgery with
a special interest in disability evaluation aml rehabilitation. He is
presently the orthopaedic consultant for the Aspen Ski Company,
and is joining the Orthopaedic
Associates of Aspen on a pare-time
basis as a consultant in rehabilitation and disability evaluation.

Saar A . Porrath '6 1 ► of Beverly
Hills, Calif., \vaselected president
of the National Consortium of
Breast Centers .

Murra y A. Yos t Jr. '66 ► has
been elected vice chairman of the
Buffalo Section of The American
College of Obstetricians
and
Gynecologists. Yost is an associate
clinical professor of obstet rics and
gynecology and assistant clinical
professor of psych iatry at the UB
School of Medicine.

J ohn L. Kiley ' 6 2 ► is medical
director of Charter Hospital in Las
Vegas, Nev.

John E. Spoor '6 6 ► was named
a fellow of the American College
of Emergency Physicians, appoint-

tee Forum.

1960s

Mar vin
Ku r ia n '6 4 ► has
been named to membership on
the Board of Governors of the
American Biographical Institute
Research Association . This prestigious board position carries with
it the tide of Deputy Governor.

ed assistant clinical professor of
medicine at Columbia Un iversity
and listed in Who'sWhoin rheEast.
T homas P. O'C onn or '67 ► has
returned to Western New York
to become directo r of radiation
therapy at Western New York
Medical Park, a new facility in
West Seneca .
Paul S. Schu lman '68 ► of El
Cajon, Cal ifornia, was named a
fellow of the Ame rican College of
Radiology.
S.K. Bosu '69 ► has returned to
the United States after serving as
a consultant to the Lagos State
Government in Nigeria.
Da vid M. Sherer '69 ► writes,
"Took a trip around Lake Erie last
summer with my 13-year-old son,
saw baseball in Cleveland, Detroit
and Toro nt o and stopped in at
Capen Hall. Had a brief reunion
with professor Milgrom. Otherwise
l'm involved in our Credit Union
Board,ski patrol, Golf Club Board
and have sung with the Seattle
Opera. Am having fun with my wife
Barbara and th ree chi ldren. I love
Scanle." Sherer isdirecto r of Clinical Laboratories, Group Health
Cooperative of Puget Sound.

1970s
Elliott Brender '70 ► was elected
chief of the depa rtment of surgery
at Garden Grove Hospital, Garden Grove, California.
Jam es M. Bak er '7 0 ► writes,
"Besides a small town family practice, I am do ing phase Ill cli n ical
studies for phannaceutical companies in development of new drugs.
Miko, my wife, and two children
are doing well."

BUFFALOPHYSICIANAND BIOMEDICAL
SCIENTIST

�________________
_______,....
....

39

I ra L. Salom '77 ► was elected
a fellow of the American Co llege
of Physicians and certified in geriatric medicine.
Russell J. Van Coevering II '77 ►
was elected president of the New
York State Society of Obstetr icians and Gy neco logists.

Salvalore
A.DelPrete
, M.D.,'78

Leela nd A. J ones '73 ► after
completing a residency in psychiatry, Jones left his North Caro lina
family practice to return to Buffalo, where he was named director
of the medical-psychiatry unit at
Buffalo General Hospital.
Michael Rad e '75 ► has been
elected to the Board of Governors
of the American Co llege of Su r•
gcons as a Governor-at-Large from
Western New York. He is a clinical instructor in surgery at the UB
School of Medicine and Biomedical Sc iences.
Elaine S. Chirlin '77 ► has a private practice in chi ld, adolescent
and adult psychiatry in Cincinnati, Ohio, where she also works
in pub lic sector mental health.
Ch irlin has three daughters.

OrestesG. Rosabal '77 ► waschosen to represent the State of Florida
as Co uncilor for the Southern Medical Association, a multi-specialty
associat ion providing continuing
medical education and practicerelated benefits for physicians.

Salvatore A. DelP rete '78 ► of
Fairfield, Connecticut, was the
1990 recipient of the Dr.Melville
G . Magida Award, presented
annually to a Fairfield Cou nt y
physician fo r "demonstrated
notable capability in patient rre-at•
menr and care."

1980s
Robe rt Brac o '80 ► is the occupatio nal medicine physician at the
SW Center for Occupational
Health and Safety of the University of Texas School of Public
Health in Houston.
William N. Capicotto '80 ►
of Buffalo is a fellow of
the Ame ri can Academy of
Or th opaed ic Surgeo ns.
Daniel Paul Schaefer '81 ► has
written rwo chapters in che new
Adas of Con t emporary Op h tha lmic Surge ry.
He is an assistant clinical professor in the department of ophthalmology and assistant clinical
professor in the department of ear,
nose and throat at the State University of New York at Buffalo.
Mark Ch ung '82 ► is in private
practice as a pulmonologis t in
Lo Alamitos, California. He is
a lso a lieutenant commande r
with the U.S. Naval Reserve
Medical Co rps.

BUFFALO PHYSICIAN ANO BIOMEDICAL SCIENTIST

Mich elle D. Leon '82 ► is the
new assistant program director of
the integrated reside ncy in eme r•
gency medicine currently being
establis hed at the University of
Co nn ecticut Medical Cente r.
Paul N. Rosenberg '82 ► writes,
''Living happily in Rochester, New
Yorkarea with my wifeSuzanne and
d1ildren,Aaron, 6,andShelby,3. My
practice is limited to oculoplascic,
reconstructive and orbital surgery."
Adolph Soto Jr. '83 ► of Bronx,
New York, was recentl y appo inted
unit chiefoflinco ln Hospital, the
city's first bilingual, bicultu ra l,
inpatient psychiatric program.
R obe rt W. Lasek '84 and Colette
► arc living in Danville, Pennsy lva ni a.
"Colette has com pieced her cardiology fellowship at Geisinger Medical Center and joined the staff,
specializing in echocardiography,
rransesophageal echocardiography
and imraopcrative echocardiography. I comp leted a fellowship in
medical educa t ion at the University ofTexas-Southwesrem Medical
Cente r (sponsored by the Emergency Medicine Found ation and
the American Co llege of Emergency Physicians). I am active ly
involved in teaching eme rgency
medicine at Geis inger Med ica l
Cente r. We recently celebrated our
fifth wedding ann iversary."

R. (Pruefer) Lasek '84

Joh n J. Picano '84 ► has completed a two-year clinical fellowship in neuroradiology at Massachusetts General Hospital and
is now in private practice in New
Hartford, New York. He and his
wife, Lynn, have rwo children,
John, 3, and Cara, 1, and are
expecting their third child in May

Marc J. Koblick '84 ► moved to
Daytona Beach, Florida after completing an opht halmology fellowship in New Orlea ns, Louisiana.
He proudly annou nces th e birch
of a daughter, Jacqueline Ann,
born July 13, 1990.
Andrew C . Friedman '85 ► finished a ge n eral surge ry res idency in Buffalo and has started
a plastic surgery residency at Case
Western Reserve.
Mark Ross Comaratta '85 ► has
return ed co Buffalo afte r comp let•
ing a retina fellowship. He and his
wife Kate have two childre n.
Kevin L. Donovan '85 ► was
appo inted chief of the anes th esiology serv ice at VA Hospi tal in
Nashville, Tennessee. He and his
wife, Shar, are expec tin g their
fourth child in March 199 I.
Nicholas D' Avanzo '86 ► is
enjoyi ng private pediatric practice with two partners in the
H amptons, N.Y.
Jean Ann (Comaratta) Marfurt
'86 ► proudly anno un ces the
birth of her son, Ryan William,
born on August 25, 1990. She is
practicing pediatrics with two
partners at 1630 Maple Road,
Williamsville, New York.
Debra Ann Gould '87 ► finished
a family practice reside n cy in
Rochester,New York,
andhasaccepred a two-year position as National
ResearchService Awa.rdprimarycare
fellowwith the department of family
medicine at the UniversityofWashington, Seatt le, Washington.
Jill E. Koeh ler '87 ► ann ounces
the birth of a daughter, Alaina Joy
Moreno-Kochler, on December 17,
SPRING 1991

�------------------------

::,~

,:.:----------------------

---

s 11

40

D avid R. Bl oo m '89 ►
announces the birth of a baby son,
Annunzio Joseph, 7 lbs. 6 oz. on
November I , 1990. Bloom is an
assistant clinical instn1ctor of family medicine and clinical assistant
for undergraduate affair; at the
University of California at Irvine.
Ca rlos Robe rto Jaen '89 ► is
senior clinica l instructor and resident in the department of family
medicine at CaseWestern Reserve
University School of Medicine.

Donnico
L Moore
, M.D.,'78
1990, weight 7 lbs. 11 oz. Koehler
1san attending physician at Hurley
Mec.licalCenter in Flint, Michigan.
Do nn ica L. Moore '87 ► writes,
"Robe rt Man ella '88 was recently
hired by Sandoz Pharmaceuticals
as an assistant director of medica l
operations in rhe cardiovascular
area - the fourth UB MD to be
hired by Sane.lo: in three years!
(Other;: Evan Dcmest ihas '87,
now at Bristol-Meyers-Squibb;
Michael Sabo linski '88, a=iate
director, medica l operations am!
myself). Perhap;, this rrcnJ has to
do with the required Medical Care
Organization courses we cook."
Moore now heads a new Jepartmcnt within Sandoz Pharmaceuticab - The Medical Educmion
Center. The Center will develop
eJucarional programs for physicians and medical student;, on
osteoporosis anJ rdatec.l metabolic
bone disorders. "My husband
(Stan Bernard, MD, MBA) ,me.I!
have settled in central New York
and love the rural lifestyle while
being close to New York City and
Phi ladelphia. Sec y'all at our Fifth
Reunion!"

SPRINt11991

D ebra M. Omi atek ' 89 ► transferred from the program at St. Elizabeth's in Utica to finish two years
of family practice residency in
Niagara Falls at the Niagara Falls
Memorial Medical Center.
C harles Eve rett '89 ► and his
wife, S,mdra Everett '88, and their
son Kristian, delight in announcing the new addition, Nicholas,
horn, August I 7, 1990.

Obituaries
Fr ancis M. C rdge ' 19 ► of Santa
Barbara, California, died October
17, 1989 at the age of 95.
Au gustus ]. Tranella '39 ► died
October 30, 1990 at his home in
Greece, New York, after a long illness. An obstetrician, Tranel!a
delivered more than 2,000 babies
at Highland Hospital before his
retirement in 1978.
John F. Moran, Ph.D. , associate
professor of biochemistry at UB,
died Wednesday, Feb. 20, 1991 in
hi; home in Snyder. He was 55.
Moran served from 1983 co
L988 a;, assistant to the dean for
facilities planning at rhe medical
schlx&gt;I. In that capacity, he wa,

the coordinator
between the
school's faculty and the architect
on plans for renovation of existing
facilities and the construction of
a $30 million addition to the medical school, completed in 1988.
A native of Cleveland, Moran
joined the UB faculty in 1964 as
a research associate in the Department of Biochemical Pharmacology in the School of Pharmacy.
He was named an assistant professor in the medical schoo l's Department of Biochemistry in 1967 and
associate professor in 1970.
From 1975 to 1976, he w,1sa
visiting associate professor in the
Department of Physiology at the
Case Western Reserve University
choo! of Medicine.
Moran was the recipient of a
Chancellors Award for Excellence
in Teaching, Distinguished Service Award from the UB medical
school and a Siegel Award Commendation for excellence in
teaching medical students.
Murray J. Ettinger, acting chair
of the UB Department of Biochemistry, noted that Moran "put
endless hours, energy and empathy
into coume lling students. He was
the sta lwart of the undergraduate
biochemistry program and, more
recently, the advanced biochemistry course for medica l and graduate students. Whatever he did,
he put his heart, soul and humor
into it. His persona l efforts helped
countless students over the years."
Director of undergraduate studies in the UB Department of Biochemistry from 1968 to 1984,
Moran haJ served on the UB Faculty Senate, the medical schoo l's
Faculty Council, the steering committee of the UB Department of
Biochemistry and the curriculum
committee of the UB School of
Pharmacy.
Moran also was active at Christ

JohnF.Moran
, Ph.D.
the King Church, Snyder, where
he was head of the usher's organization, a post he held since the late
1970s, and a former officer of the
Christ the King Schoo l Parents'
Guild. He also was a former treasurer of the Parents Guild of Villa
Maria Academy.
A 1958 graduate of John Carroll University, Cleveland, Moran
received a master of science degree
magna cum laude from the Univers ity of Ottawa in 1961 anJ a
doctorate in biochemistry from
McGill University in Montreal in
1964. An expert in metabolic biochemistry, he was the co-author of
more than 30 scientific articles .
He is survived by his wife, the
former Karin Yax; two sons, Kevin
and Patrick, both of Snyder, a
daughter, Megan, of Snyder; and
a sister, Martha O'Donnell of
Cleveland, Ohio.
Contributions in Moran's memory may be made to the University
at Buffalo Foundation, designated
for the John F. Moran Memorial
Fund in the UB Department of
Biochemistry, or the South East
Community \Xlork Center, I 81
Lincoln Road, Depew, N.Y.

lll 'FFALO PHYSIC IAN AND BIOMEDICAL ~IENTIST

��BuffaloPhysicianand BiomedicalScientist
StateUniversityof New Yorkat Buffalo
3435 Main Street
Buffalo,New York 14214
Address
Corre&lt;tioa
Reqwested

958

MR. CHUNG
- KA! HUANG
HEALTH 5CIENCc LI RAqy
A880 TT HALL
CAMP US ,r1AI L

Non-l'ro hc Org.
U.S. l'osc~e

PAID
Buffalo,NY
Pcnmt No. 3I I

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�VOL. 25 , NO. 4

.......................................

. ..........................

. ........

. ....................... AUTUMN

1991

IJ Research
II HospitalNews
II TheResignationof NealRzepkowski.Forced out of
Prescriptions
for pain havechanged, andso
havedoctors'attitudes aboutthis major patient
complain
t. Page20.

Brooks Memorial Hospital in Dunkirk and caught
in the storm of controversy that followed the
release of the CDC's new guidelines governing
HIV-infected
health care workers, Neal
Rzepkowski is a physician at peace with himself
and his life.

IEJInWhoseHands?The Patient Self-Determination
Act should put patients more firmly in control of
their own medical destinies.

m

Congratulations
. YouHaveBeenAccepted!
Getting into

UB medical school is more com petitv e than ever.

E3The Classof 199S. A special photo directory insert
of the School of Medicine and Biomedical Sciences' entering class.

E!J
Ending
the Agony•
epidemic of pain.
EJMedicalSchool
EiJAlumni

TheHopeClinic
lets UB's
medical
studentsgive
backlo their commu
nity.
Page24.

ew techniques to treat the

mPeople
mClassnotes
*TheJamesPlattWhite
Neal Rzepkowski, M.D., speaks out
onthecontroversythat cast himhis
jab. Page 6.

Societylavndtes
its
"'Thotsancl
at a Thotsancl"
campaign.Page28.

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11
., '

.

Studyshowspetdogs
aremorecalming
thanclosefriends

is that subjects with their pets presen t
were apparently less psycho logically
threaU!ned than were subjects with their
friends present or subjects withou t a
comp2mion," the researchers wrote. +

he presence of man 's best friend
- the four-legged variety - is a
more calming influence during
the performance of a stressful,
evaluative task than ,
that of a close human friend, UB research ers have found.
The researchers believe
the resu lts of the
study, published in a
recent issue of the

Journal of
Personality
MyFriend
and Social
Psychology,can be amibuted to the fact
that dogs are seen as non-judgmental
and non-evaluative, while friends are not.
The study was conducted by Karen M.
Allen, Ph.D., director of training for the
Rehabilitation Research and Training
Center on Community Integration of
Persons with Traumatic Brain Injury;
James J. Blascovich, Ph.D., director of
the Center for the Study of Behavioral
and Social Aspects of Health; graduate
student Joe Tomaka, and Robert M.
Kelsey, a post-doctoral fellow.
The researchers measured autonomic
responses of 45 women who reported
close relationships with their pet dogs
during two sessions in which the subjects performed stressful menta l arithmetic tasks.
With pets present, participa nts' autonomic responses remained at baseline
while performing the mental arit hmetic
tasks. BULwith friends present , participants ' autonomic reactivity increased
dramatically.
"Our interpretation of these findings

e

B

U

FFA.

L

O

PHYSIC

I

AN

B

Y

SUE

W

U

ETCHER

UB1~esearcher
receives
gra11t
fromACS
UB researcher has received a
$240,000 grant from theAmerican Cancer Society to study the
relationship between diet and
the development of cancer.
~ Jo Freudenheim , Ph.D., assistant professor of social and preventive
mediC"ine, will conduct three studies
under the two-year grant.
One will examine the role of dietary
intake in the development of premeno pausal breast cancer, endometrial cancer an,d pros tatic cancer by focusing on
information on dietary intake and health
and persona l factors collected in interviews with residents of Erie and Niagara
counties with cance r and a group of
matched controls.
The sLUdywill look at the association
betwe,~n the cancers and the intake of
fat, calories, carotenoids, vitamins, fiber, zinc and cruciferous vegetables .
A second study will focus on 58,000
older, llong-tenn New YorkState residents
who completed a questionnaire in 1980
about their health and personal factors.
"The group is being followed through
the New York State Tumor Registry, "
Freudenheim noted. "Sufficient cases
have now occurred to allow for a prospective analysis of dietary factors in
cancer of the lung, breast, colon, rectum, ovary ,endometrium and prostate. "
The third study '&lt;viiilook at data on
controls from the first sLUdyto examine
the correlation of factors such as energy
expen ,diture, occupational time and lei-

A.NO

B

I

OMEDtCA

L

SC

i

sure time with dietary practices. Smoking, reproductive history and socioeconomic status also will be among the
+
factors to be studied .
-

BY

A

RTHUR

PAGE

Innovative
technique
usedto repairaneurysm
eurosurgeons at the State University of New York at Buffalo
used an innovativeendovascu lar
procedure LO treat a cerebra l aneurysm in a mother of eight ,
eliminating the need for risky
surgery and giving the
woman a "second
chance " at life.
The neurosur geons , led by L.
Nelson Hopkins,
M.0., chair of the
neurosurgery
de partment at UB and
chief of neurosurgery at Millard Fillmore
Hospital, threaded a micro-catheter
through the patient 's blood st ream and
into the aneur ysm . A small coil of platinum wire was placed in the aneurysm
and a low-voltage banery current passed
through the coil , causing a clot to form
and seal off the aneurysm. The coil was
released within the aneurysm and left

I

EN

TI

ST

A

U

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1

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9

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·····················

· ···········································

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m

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WU

..

low-up Clin ic and director of the
oncology section at The Children 's Hospital of Buffalo. Also on the team were
Michael A. Zevon, Ph.D., Geoffrey
Lowrie, NinaSeigelstein and Brenda Hall.
The study focused on 25 male and 35
female former cancer patients 18 or older
who had been diagnosed with cancer five
or more years earlier.
Among the 39 children born to the
male former patients, three had minor
congenital anomalies. The frequency of
BY
ARTHUR
PAGE
single anomalies was 7.9 percent, compared with 13 percent for the general
population, the researchers reponed.
Congenital anomalies occurred in five
of the 63 children born to the female
former patients.
The incidence of venuicular septa! defect
as a single malfom1ation was 3.85
he use of chemotherapeutic agents
per
cent
in female children of the white
to treat children and adolescenLs
with cancer does not appear to female formerpatients,ascompared with
increase the frequency of con- 0.034 percent in white female infants in
genital anomalies in their chil- the general population. The incidence of
tetra logy of Fallot was 2. 78 percent
dren, according to researchers
among
the male offspring of the white
affiliated with UB and Roswell Park
female
former
patients, compared with
Cancer Institute.
0.024
among
white
male infants in the
They report in the lead article in Lhe
July 18 issue ofTlie New Englandjoumal general population.
Both women who gave birth to a child
of Medicine that with Lhe exception of
one agent, dactinomycin, a higher inci- with a cardiac defect had received
+
dence of congenital anomalies was not dactinomycin in chemotherapy.
BY
ARTHUR
PAGE
found in a follow-up study of 60 former
cance r patienLs.
In the case of dactinomycin,
structural congenital cardiac defects were found in 10 percent
of the infants born to women
treated with the drug compared
with a 0.60 percent rate for infants in the general popu laLion.
Daniel M. Green, M.D., professor of pediaLrics and chief of
the oncology secLion in the department
of pediatrics
at
Roswell is principal author of
the study. Green also is director of Roswell's Long-Term Fol-

behind to permanently seal off circula tion and protect against future hemorrhage.
The neurosurgeons from UB and
Millard Fillmore are only the founh
group in LhenaLion to successfully perform the procedure on patients.
"I feel like I'm lucky to be alive," says
Jacqueline Talada, 49, who suffered from
progressively severe headaches and seizures due to a "giant aneurysm" at the
base of her brain. "I feel I got a second
chance to be alive, Lhanks to Dr. Hopkins
and th e medical field."
Talada underwent the procedure July
29 at Millard Fillmore under local anesthesia. Discharged three days after the
procedure, she has had no more seizures
and her headaches have improved tremendously.
The new procedure was developed in
1990 by Dr. Guido Guglielmi, M.D., and
a team of neuro-radiologists at the University of California at Los Angeles. +
SUE

~·
,.

.

BY

·~

sample ofBuffalo households.
Also working with
Trevisan, associate professor of social and preventive medicine and
acting chair of the UB
Department of Socia l
and Preventive Medicine, were Vittorio Krogh, M.D., Linda
Klimowski , Susan Bland and Warren
+
Winkelstein, M.D.

Chemotherapy
in
childhood
notshownto
increase
birthdefects

ETCHER

Lackof siblingsincreases
riskof hypertension
eing an only child increases your
risk for high blood pressure, accordi ng to UB researchers.
Ina study of 1,472 whiteadulLs,
researchers found that the mean
systolic and diastolic blood pressure and prevalence of hypertension were
higher in those without siblings.
In the case of systolic blood pressure
and prevalence of high blood pressure in
both sexes and diastolic blood pressure
in men, the differences were statistically
significant, Maurizio Trevisan, M. D., and
colleagues reported in a letter in The New
EnglandJoumal of Medicine.
The UB study focused on 6 76 men and
796 women, age 20 to 70, who participated in a survey involving a random

BU,.FALO

PHYSICIAN

ANO

BIOMEDICAL

S

CIENTIST

AUTUMN

I

SI

9

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�1&amp;n1··················
....
. ····

~

SistersHospital
begins
modernization
proiect
ork began in mid-October
on Sislers Hospital's $42
million
modernizalion
projecl.
The 28-month project will
provide enhanced patient
treatment areas and improved seuings
for visitors and employees. Major components of the project include new coronary and intensive care unilS, new operating rooms, ambulatory care wing,
emergency depanment, head and neck
center and a new lobby and elevator
bank connecting corridors for easier access to all areas.
The project will also address major
code and safely issues along with increased cool ing capacity and air conditioning and medical gas systems. "Much
of the work will be done within the
existing structures so those passing by
the hospital will not be aware of most of
lhe work," said Timothy J. Finan, Sisters' executive vice president.
The projecl will begin with lhe
addition of lwo floors atop the
hospital's skilled nursing facility to house a
..t;J ....,._I I
new 16-bed ICU and
eight-bed CCU. A
·'
_!
connecting corridor
will allow for direct
.;..W...
access between the
new intensive care
units and operating
suite to be constructed. Sisters will
also consolidate its
laboralories to the hospital's
fourth floor.
The present operating room
space is slated for renovation to
house pre-admission, urology , endoscopy and outpatient surgery.
The project also includes construe-

fl

0

BUf",.A.LO

PHYSICIAN

· ········································

· ·············

tion of a 10, 760-square-foot building
behind the hospital to accommodate the
hospital's information systems and finance depanmenlS.
Also scheduled for renovation and
realignment is a significant portion of
the hospital's first floor. A new main
lobby will be constructed at the present
location of the finance and information
systems departments. Inpatients and
visitors will pass directly through the
new lobby to a new bank of elevators
linking them directly with patient floors,
surgery and critical care units.
OutpatienlS will use the new entrance
and connecting corridor to a completely
remodeled ambulat0ry care wing which
will incorporate the emergency department, outpatient department , women's
services, corporate health services and
satellite radiology and phlebotomy labs.
The emergency department will also gain
a new entrance to enhance traffic flow
for walk-in patients.
The project was designed by the Rochester firm of DeWolff Partnership,
+
Architects.

ffi §~ ffl

--,i~:

Herzigto heodbone
morrowtronsplontotion
unitot Roswell
eoffrey P. Herzig, M.D., has been
appointed
d irector of the
Divisions of Hematologic
Oncology and Bone Marrow
Transplantation, Department of
Medicine, at Roswell Park
Cancer lnstitute.
Former professor of
medicine, division of
hematology/oncology
and head of the bone
marrow transplantation program at Washington
University
School of Medicine in
St. Louis, Herzig is an active member of
many professional organizations, including the American Federation for Clinical Research, American Society for Clinical Oncology, American Association for
Cancer Research and American Society
of Hematology. He has written over 80
scholarly papers, monographs
and book chapters.

j:~:;!;~
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· ·······

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Artist's rendering
of Sisters
Hospitol's
newlobby.

ANO

8tOMC:DICAL

SCIENTIST

AUTUMN

1

9

9

1

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· ············

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A Phi Beta Kappa, Herzig received his
medical degree in 1967 from Case Weslern Reserve Universily in Cleveland and
his medical residency training at Bronx
Municipal Hospirnl in New York. He
also served as senior invesLigator, Pediatric Oncology Branch, at the National
Cancer Institute.
The bone marrow transplant program
performs both autologous and allogenic
transplantations and conducts research
designed to improve long-term survival
rates for transplant palients. The division of hematologic oncology treats pati en ts with leukemia , lymphoma,
myeloma and other hematologic problems and studies the pharmacological
and biological basis of disease progression and response.
+

BGHparticipates
in
JCOAH
test proiect
he Buffalo General Hospital has
been selected to participate in the
field testing of indicators , or "performance measures, " for theJoint
Commission on Accreditation of
Healthcare Organizations.
The Lesting represents the firsl largescale evaluation of theJCOAH 's trauma
care, oncology care, cardiovascular care,
medication use and infection control
indicators. The indicators are designed
to support hospital efforts to assess and
improve the quality of patient care.
Buffalo General will participate in the
testing of infection control indicators.
Testing is expected to last about two
years.
The indicator development project is
part of a JCAHO project begun in 1986
to modernize its accreditation process.
The new process potentially uses both
clinical and organizational performance
data to measure an organization 's ability to deliver quality health care.

BUF'

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BGH joins other test sites selected
from volunteer accredited hospitals
throughout the nation. Test site activities include evaluating hospitals ' ability
to use computer systems to collect indicator data and to transmit the data electronically to the Joint Commission. A
second activit y involves evaluating the
reliabilit y and validity of the indicators
to assess their potential usefulness to
improve the quality of patient care and
services.
+

~

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-

-

-

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-

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• ·····lrBl

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primary physician. Referrals are based on patient need, geographic location and accessibility to
follow-up treatment sites.
Some of the benefits of
the HIP program include
early intervention and
immediate response Lo
potential problems while
patients are still hospitalized, according to program counselor Kathleen
McDonald, R.N.
Early treatment of alcohol-related problems
also reduces the chance of patients developing further physical or psychological complications , McDonald said.
According to statewide data gathered
since H!Ps were implemented in 1989,
approximately 25 percent of patients
admitted to hospitals have alcohol or
drug-related conditions.
+

BGH
adoptsalcohol
intervention
program
uffalo General Hospital is one
of 18 hospitals statewide to
,
developaHospitallnterven~ V
tion Program (HIP) for pa- ,,
./. -~
tients with alcohol-re'
lated problems .
•
f
The new program , the first
in Erie County , offers counseling , education and linkage and referral services based
on inpatient screening on des~~~~
ignated units. Screenings con- ,
~ :: ,.

ff. ~

i~- ·~ff~
~\\'- -

sist ~f. a series of questions
admm1stered by nursmg staff
with the permission of a patient 's
AND

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�I

eal Rzepkowski'.sstory is straightforward and
only slightly bitter.
The 40-year-old UB assistant professor of
medicine spends his days in the Spiritua list
haven of Lily Dale, New York, an oasis of
tranquility amid the storms that have
gripped his life.
Diagnosed in 1985 as being
infected with the human
immunodeficiency virus the virus that causes AIDS Rzepkowski was thrust into the
nationalspotlightlastsummer

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- osit
ive
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�when he became the first physician lo
disclose his HIV-positive status under
new guidelines governing health care
workers infected with the virus. The
Centers for Disease Control issued the
guidelines last July after months of delays and deliberations. As a result,
Rzepkowski was forced lo resign his fulllime emergency room post al Brooks
Memorial Hospital in Dunkirk amid a
nurry of national press coverage.
Rzepkowski does not, al this point, have
AIDS, though he is realist ic about the
likely outcome.
The possibility of an early death, he
says, "hangs over my head like the Sword
of Damocles."
Save for a half-day of work a week at
the Immunodeficiency Clinic at Erie
County Medical Center, Rzepkowski's
practice is non-existent. "l suppose l
could start a private practice. l know I
would get a lot of I IIV-negative palienlS
coming 10 see me. But a private practice
and my past experience of having one means that you're on call with a full-time
work week, on call al nighlS and up
weekends."
So Rzepkowski is careful to gua rd his
resl and nutrilion. "I'm not going to have
a private practice to prove a point."
Monitoring and appropriate medical action, he knows, can delay the onset of
AIDS.
Rzepkowski iscoping with the stresses
of sudden celebrity. He is perhaps a little
weary of questions posed by yet another
interviewer. His story has been reported
by the national press, and further probed
on talk shows by Oprah Winfrey and
Jane Pauley in her "Real Life" series.
Today, Rzepkowski feels fine though
he's occasionally fatigued and does have
hairy leukoplakia - a white, possibly
precancerous, patch-on
his tongue, "a
sign of HIV-positivity/ he relates matter-of-factly. He is above all, an educator
on the AIDS nightmare who doesn't shirk
from the known faclS,even when they so
impinge on the tranquility of the moment. There is no time for easy dissembling when his mission is the truth.
"The average time between getting
infected and becoming seropositive, and
developing symptoms is 10years- that's
the average time. Some people take a lot

o

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longer. But it is thought that more than
90 percent of these people, eventually,
given enough time, will go on to develop
AIDS." Rzepkowski's own frank statistical analysis may mean he has only a few
years left.
So often, he notes, the public con fuses HIV positivity with having AIDS
ilSelf. "l don't have AIDS. I have HIVpositive teslS. A lot of people confuse
that. Like I say, you can be HIV-positive
for 10 years before you have the end
stage of that virus, which is AIDS."
Rzepkowski has owned his small Lily
Dale home for four years, living in the
century-o ld community for metaphysical education for the last year and a half.
He went to high school in Dunkirk, then
moved to Troy where he began studying
Spiritualism and earned his B.S. from
Rensselaer Polytechnic lnsti tute in 1974.
Then came medical school at what was
then SUNY Upstate Medical Center in
Syracuse (M.D., 1978), followed by a
fam ily
practice
residency
in
Schenectady's SL Clare's Hospital and
seven more years as director of the
hospital's Family Health Center.

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BIOMEDICAL

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Board certified in Family Practice,
Rzepkowski was drawn to Boston's
Fenway Community Health Center in
1988, where he could care for AIDS
pa tienlS in the sympathetic setting of a
gay-run institution. Openly gay, he
"wanted to go learn about the virus and
care for these patients." In 1990, weary
of high renlS and neighborhood crime,
he returned to Lily Dale, where he could
tend his garden and consider an uncertain future.
By this time, of course, Rzepkowski
knew he had the virus. "The odds are,"
he says, that he contracted it "in 1981 or
1982," before the human immunodeficiency virus was isolated and "safe sex"
practices were advocated. Slowly he revealed the news to a circle of friends, and
gradually lO professional people he
thought should know.
"In July 1985, I tested positive; the
test first became available to the public
that month. Wi thin a short time, I told
the director of my program and the nurse
epidemiologist at the hospital. They were
the only ones who knew - at the time,
they were the only appropriate people lO

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tell. I also had cared for HIV-positive
patients ever since the test first came
out. I shared the fact that they were not
alone and that I was in their same boat. "
This was the beginning of gradual
disclosures that led to a front-page story
in a New Hampshire paper and later, to
blockbuster announcements in the local
and national media last summer. "It was
open, " Rzepkowski ins ists of the subject. "I also shared it \vith a few of my
HIV-negative patients. When I applied
for the position at the Fenway Community HealLh Center , I told them l was
HIV-positive. "
"At the end of 1988, I decided it was
worth my while to educate the public in
an even more direct fashion than I had.
I had been giving lectures across the
country on HIV-related topics, and had
started to share with public groups that
I, too, was an HIV-positive person and
that peop le needed to put a face on this
condition and see that human beings are
walking around with this and are perfectly healthy. "
Rzepkowski then took up a series of
speaking engagements to public groups
and medical assemblies, including the
New York State Academy of Family Physicians lastJuly. "Just recentl y, I spoke to
the Tennessee Academy of Medicine and
the Tennessee Academy of Family Physicians. '' During these presentations, I
would say, 'I am also HIV-positive.' In
July of 1989, I gave a public forum in
Keene, New Hampshire, sponsored by
the American Red Cross, on AIDS, dealing \vith the blood supply and how you
get the virus and how you don 't. There
were news reporters there who asked if
they could print this, and I said, 'I'm
open about it,' and so I was on the front
page of the Keene newspaper.
"When appropriate, I put this information on my medical applications . The
medical application doesn't ask specifically whether you're HIV-positive or not.
So I didn't need to bother with that
question. They do ask whether I'm capable of performing medical duties which
I am. So that was put down.
"LastJune , I went for a physical exam
which doctors have to do as employees.
I told the doctor in Buffalo that I saw,
'Look I'm HIV-positive and you should

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know that..' When it was time to fill out
my application for work, the question
was, 'Are you capable of performing your
duties medically ,' and he put yes. Asked
for other comments, he said, 'You know
doc, I have to put down that you're HIVpositive.' I said, 'That's fine."'
Rzepkowski 's former employer, Joseph Gatewood, M.D., director of medical services for Spectrum Emergency
Care of St. Louis, which sub-cont racts
out to Brooks Memorial in Dunkirk to
supply them with emergency room physicians, puts it this way: "This is a problem that goes beyond personal freedoms
and rights to know. It's question of physicians and their capability of taking care
of patients. The point is that the public is
so frightened of this as an unknown fear
that their demands to know whet her the
doctor has a particular illness - when
the statistical chance isso small - strikes
me as an irrational reaction. It is much
more dangerous to have a physician who's
suffering a hangover from having had
too much to drink the night before. "
In applying for privileges at Brooks,
Rzepkowski was asked whether he had
been taking any medicine regularly.
"Well, I had put 'no' on my original
application last year. But this year, I am
on AZT regularly. The next question is
why, and I put down, 'because I'm immune deficient with HIV.' So that is
when the administration knew , in April

~

Healtll Care
Workers W'rthAIDS
S ince the epidemi c ~egan .
nearly a decade ago, the..CD C
has reported AIDS in the Jol!owing fl.Umb
ers of health care.
wQrkei·s. ;J"h
e numbers ofH IV~
positive het.ith care workers,
which are not reported here, of
course, .are greater.
Nurses•···-·· ····· .. •··••···· 1,~ ;,-

Health aides ......... ...... 1,101
Technicians •.•..•...•. .. ... ...1'41
Physicians ......... ........... . 703
' Paramedics ......... ... ....... 116
Therapltrts ..... ..... .. ......... ~ 19'
Dentists/hygienists ..••.•• 17 1

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of'91. The direct0r of ER and the appropria te doctors in the hospital knew Jor
over ayear about this and had previously
called the state health department, and
had been reassured that, in fact, I was
\vithin my rights to work, that I was not
a danger to anyone. "
Brooks Hospital Administrator Richa rd Ketcham acknowledges
that
Rzepkowski told the ER director of his
condition shortly after he was granted
privileges there in April of 1990. According to Ketcham , the administration
knewofhiscondition when Rzepkowski
completed his reappointment application in the spring of 1991.
The piccure darkened, though, following the release of new CDC recommendat ions July 12. "I think the hospital administration became nervous at
this point. According to the new recommendations, not law, but recommendations, HIV-positive health care workers
should refrain from 'exposure-prone '
procedures. They ultimately left the definition of exposure-prone up to each
individual hospital. At the time this came
out, I was called by Dr. Joe Gatewood.
He told me that umil we get this straightened out, I shouldn't work. 'We' re put ting you on administrative leave of absence.'"
According to Rzepkowski , Gatewood
requested input from Rzepkowski on
what exactly constitutes "exposureprone " procedures, in view of his expertise on AIDS issues. He met with
Ketcham, Gatewood and other officials
at Dunkirk 's Sheraton Harborfront Inn .
"I thought, this is nice, they're wanting my input on what 's 'expos ure-prone .'
Well, I got to the breakfast meeting and
they said, 'We've come up with a list of
35 exposure-prone procedures we feel
you can't do; therefore you can't work in
our emergency room. Therefore, wesuggesteitheryou voluntarily withdraw your
privileges for an indefinite period of time,
or we can dismiss you. But if we dismiss
you, you'll have to put this on all your
resumes and explain it all if you ever
want to apply for privileges again.
"'What is your decision, doctor? ' So,
of course, my free will decision was to
voluntarily withdraw. This looks nice in
the paper- that 1voluntarily withdrew,

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�bm what would your choice be? 1f I
didn 't voluntarily withdraw, I would have
The possibility
of an early
deal
gotten fired. "
There is some anger in Rzepkowski's
voice as he tells his story, but he claims
to understand the "human emotions"
that precipitated it. "Given the circumstance of a small hospital and their level
of education about AIDS, and not having
e)cpen input into the 35 exposure-prone
procedures, it's understandable that they
didn't want me to work there. "
Asked to comment on Rzepkowski's
story, Ketcham says, "It's a relatively
accurate portrayal. I'd like to reiterate
that Dr. Rzepkowski has handled (the
matter) very well, superbly, in fact. He
was honest and open with the hospital.
We tried to be open with him. "
The hospital 's list of 35 exposureprone procedures was not arrived at by which I'm afraid it is - then it's critical
ln Ketcham 's view, the issue of inofficials at the Harborfront lnn meeting,
that the needs of health care workers be formed consent is a compelling one in
Ketcham states. Rather, they were deter- addressed. Because clearly the risks of the context of exposure-prone procemined before by members of an ad-hoc transmission of communicable disease dures. "Some ER patients are not in a
committee appointed by the hospital 's from patient to health care worker are position to give informed consent. In
medical executive committee. Members much greater than the other way around. other situations, if a patient chooses his
represented "appropriate medical spe"I find it personally very distressing, or her private physician - and knowcialties" Ketcham said, who then pre- as does the board of trustees and the ingly chooses an HIV-positive physician
sented their findings to the medical ex- medical staff involved in this issue, that - that is this person's choice. In ER, it is
ecutive committee and later to the board HIV is not treated in a scientific manner. usually not a matter of choice. Thereof trustees for approval.
Unlike any other disease , it is treated fore, we believe we owe an even higher
In commenting, Spectrum's Gate- through the political process. This has obligation to the community in this rewood cited his own many years as an created a paranoia, hysteria, a level of spect."
emergency physician. "It's not just a fear unlike that for any other disease.
Of the 4,100 individuals who were
business with me. My interpretation as Though much of this is unwarranted,
sent letters alerting them to Rzepkowski 's
an individual physician of the types of the reality is that hospitals must react to condition, 536 chose to be tested. None
procedures that the CDC listed in their public perceptions as much , if not more tested positive, Ketcham reports.
July document is that probably there are so, than scientific facts. Some may see
In Rzepkowski 's view, the public
up to five or six procedures that would this as ducking real issues , not being fair needs to be educated about the disease.
be truly 'expos ure-prone ' by their defini- to the physician, but I also have an "It's transmitted in certain defined ways.
tions, that an ER physician might do."
obligation to the 18,000 ER patients who l think it's fearsome because it's ultiHe noted that he wasn 't criticizing
were served by Brooks last year.
mately so deadly. That's what people
Brooks' list of the 35 procedures, nor the
"We have tried to stress the educa- fear. But if you really think about it in
process used in arriving at them. "I just
tional aspects of this issue and the fact proper perspective , yeah, it's a deadly
think that they 've listed some proce- that the risks are very small. The level of virus, but it's hard to transmit that deadly
dures that , when beuer support and as- awareness is not what it should be. A virus."
sistance is given to hospitals and there is much higher level of awareness is needed
As he continues his battle for more
better guidance from the speciality soci- ifan HIV-positive physician is to work in understanding
of AIDS issues,
eties and the CDC, some of the proce- an ER, particularly if he is the only ER Rzepkowski knows that "at any time I
dures on the list would be taken off."
physician on duty at any one time , as is could get sick. My allergies are acting
For Ketcham , the dilemma posed by the case at Brooks."
up. I ask myself , is this the allergies or do
Rzepkowski'scondition has two aspects:
And according to Gatewood, "Most I have pneumocystic pneumonia? ls this
"First , there is the scientific approach,
probably, of the 5,000 ERs in the coun- the end? Those kinds of things are alwhich would clearly indicate that the try, the vast majority have a single emer- ways lingering. But you have to deal with
risks are so small as to not even exist. If gency room physician. An ER physician it and live one day at a time, live life to its
the move is toward mandatory testingcan't limit himself to certain procedures." fullest."
+

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What

Do You TI1ink?

The Buffalo Physician a11
d Biomedical
Scientist wants LO know its readers'

"Clearly,someth~•Speculiarwasgoing011in
that office.'· Clarissa Cui111inghCl(11
, spohespcrsonfor t11e.AIDSAction Co1111cil,..refer1illgto Acer's,{a~/1 of w1ivetsalpreooutitl1L~
and sterilc·tecff11iq11c.

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11vFloridadentist.Ac~r. 011how s}iewould

•

"ILis 111ucl1
_mo1·edangerousta have &lt;1'17hys'i-thaf .UP,'heldth~ Medical Center at
cian wn~·ssufferinga l_1angover
from having Princeton's policy requiring an HIV1nfected s~rgeoh to seek · informed
had 100 m11cl1ta d~nk thci,ightbef~r'e."·
JosephGatewood,M.D .. directorcf medical consent from his patients, effecscn•icesfarSpectrum£mergotcy Car~ofSt. .tively .-restricting his practice.
Louis, which $1tlJ-comr0;c4·
11utt0 Brooks
MemorialHospitalto supplythemwith emer- "The i11h
ere11trilh1to know-forpaticn(a 11d
e co,ifigency'ro~mphysicia1is,011the risks a pdr,ient doGtoralihe_: always bas ta SUPG{__Sed
. facesfrom bei11gueatedbyan HIV-positive deniiality . •Tl1edoctordoc;sn't hal!e 10e11tup a
signboard,but therehasto be inJonntd consent
ph_y~ician
.•
~le gai11gto do invasive proceduFcs. 'First'.
"Unfortunatl!ly, this dentist ,did dono ha~· is the absolutebedrocnoJmedicine,.
not use very strong aseptic techTIJeKimbei:lyBergalis~sof this~11
orlda,rovoidniques, 'did not use rubber gloves,
ablc.·• SaiifordK1,vi1t,M.D.• vicr.cl1ainnan:of
for in~ance."
Louis _H .. Sulli .van, •the f'lational 'founclation.[or~1ifectious
- Qis· Secretary of He.. h and Human
ease~
Services, referri1'i to Florida de.ntist David J. Acer, who infected
five of his patients with tflY before
t dying of AIDS in Sel?tember 1990 ..

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tho ugh ts on the new CDC gu idelines
on disclosure of HIV-posi tive heahh
care workers under certain circum sta nces.
Please take a few minutes to wr ite
down your comments. We will publish selected responses in an upcomi ng
issue. Please mail responses to:
and BioEditor, The BiiffaloPhysicia11
medical Scientist, State Un iversity of
New York at Buffalo, 136 Crofts Hall,
Bu ffalo. New York l-+260. or fax the m
716-636-3765.

,;avefelt if herf1hysicianrejuseaLope1fon11
r;yesurgeryo11heraftershuo!Jliim$.hewas
HIV-posi¥ve. Her pl1ysicialfdid ;heppera-

"An exposure-prone procedure is
one where- it Is likely, concpivable, possible that the doctor's
blood will g~t into the patient's
circulation. That ~n be through
an open wound on the patie,;t, a
sore on the patient, but the doctor
has to bleed fresh blood ~f his into
fhe patient, or get a~ instrument
bloodied by himseff ;1ndthen, use
it on the patient. Now whether
you're wearing gloves or not, doctors don 't easil1 ble.ed when
tfley're taking care of patients."
N'e~I Rzepkowslti , M.D:
"

"Dcat.his going to catchme with my boo1~0
11.
I'm ,wt going to,sitdown·a11a'dwindl~
away•:,
1 have a messageto pass on. The one 41ing
thaL1 am 11otJoing,11owis the tbl11g1 lov~
most i11life and thµtis taking care ofpeople,
b_fcaustmedicinehas 110placl.']or thosewho.
our tale11.r."
an; HIV t,ifcctep,regtirdlrss of,Y_
Aotm, M.D., o,;
Baltimort carrliologisl'l\_cit,
suffe1ingfi'omJull-blawnAIDS three years
afier a rest tube full of HfV-contaminatcd
bloodbroke and spilled qvel' his cutji,fgcr.
Aoun sued after ad1&gt;1inistr&lt;1tors
al the hospi·
tal where /Je,was l[di11i1rg
refusedco renew
his ~ontract. The case was settledfor al!1111disclosed
.s11m.·

"Ethically
and morally ; I think
I.
.
,
shouldtnot continue with my work
without telling anybody." Dentist lll
David J. Acer to a social worker
during a hospitalization tor pneumonia a few weeks before selling
''Who do , I blame? l?,o I 'blame
his lucrative practice ii:' the SU("~
•
mys~lf? I sure don't. I never used
• mer ot · 1989, but over .a year before telling his patients he had "Doctors .rre afraid. They want to IV drugs, neve~ slept ~ith anyone
AIDS. A few days after telling · know the HIV status of their pa- and never h-?d a blood transfutients-, and doctors who work in slon. I blame Dr. Acer and every
them 6y letter, Acer died .
single _one of you bastards. Anysurgery ask us about it alfthe time.
one that knew Dr. Acer was in"TIie lisFiclosely resembles Lhc-risli of n If we get the patient's permission,
-~hicularfatalflJ' during transpoi'lationto . we give the information, oth~rwise : fected and had f~ll =blown "Jlu&gt;S
it's up to the surgeon to discover it and stood by not doing a' damn '
ahdfrom 1111
;, hospital." Albert~Lowe,ifel ,
thing about it : You are-all just as
.M.D.. of New Yorli'Mcdical College,calcu- on his, own. In many institutions,
lating the risli of transmissionfrom ·a,1HI'v- blood is illegally and surreptitiously . guilty as he was. You've ruhted
infe.:Ledsurgeo·11
t~ a patie11tat las(June's drawn on patients 1o find ou\ Jheir · ·· m]t . life and my .family's." Kiminte,:national~o,iference on AIDS held in status." Paul Rothman, M.D., presi- bedy Bergalis, the first patient to ·
dent -of Search Alliance, an Los An- contract AIDS from h.e( dentist,
Plorcnce,Italy.
•
David Acer, in a letter to Florida
geles . AIDS-res~arch organizatio&amp;
11
:rhe ultimate risk to the \atient is
be~lth officials. In a po,st script,
tot~ll_va11dgo11e Berga I is also wrote, "If laws .are
so abiiolute, so devastating, thfat "I 11ouldhm•e 1111derstot1d
it ls unt'enable to argue against
down to the AIDS clinic. A~d it_wouldn't ha;rc l\dt formed to provide protection,
: inf~fll'led consent;' ; New ' Jersey
botheredme at all to_go-dow11.
I jusl gave him then .my ~uttering and death was
\ Superior
Court Judge Philip
·oicoption. Nobodygaveme the .option." Bar~, ..•~vain.
Ca;at,man, in a· May 1991 ruling
bara Wcbb~_aziotl1er
patient infectedwith 1,;IIV "I'mdying guy,-. Goodbye.:t'

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•
ew legislalion may clarify lhe nation's debale over who makes medical decisions on
behalf of lhe comalOse and lerminally ill, placing the power lO refuse or accepl
lreatment more firmly in the hands of the patient.
According to patients rights advocates, doctors, hospital administralOrs and
auorneys, the Patient Self-Determinalion Acl, which Lakeseffect December 1, 1991
is likely to lead to more compassionate medical care by improving communicalion
between patients and health care providers. Primarily an educational law, the PSDA
mandales that federally funded health care providers publicize state laws on patient
rights to patients and caregivers alike.
But the PSDA also presents logistical, legal and educational hurdles for health
care providers: specifically, how to educate and counsel patients so that their
advance medical directives accurately reflect their unique circumstances and
values.

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��L'sexcellent law from
the perspective thaL
more people will be
infonned so they're
able to make their
own decisions, " says
Daron
Weber,
former spokesperson for the national
Concern for Dying
and the Society for the Right LO Die. "The
PSDA may lead to change by making
people aware. The key factor is going to be
compliance.just how much teeth does the
law have."
Although health care providers that
receive Medicare and
Medicaid funding must
11
comply with the PSDA
Lo receive these monies, the circumstances
under which money
would be withdrawn
have yet to be spelled
out.
Written into law as
parL of the federal Omnibus ReconciliaLion
Act of 1990, the PSDA
mandates that health
care providers give all
patients written information about stale laws
on living wills and their
rights LO refuse or accept medical treatment.
HealLh care providers
must ask incoming patients for advance
medical directives and place them in patients ' medical charts and also publicize
their institution's policy on these state
laws. For stales with few or no such laws
on the books, the PSDA requires that
health care institutions make this known.
Simplifying these mandates, a spokesman for the Health Care Finance Administration (HCFA) recommended that
health care providers develop clear statements of policies on advance directives,
write detailed action plans for staff education and community outreach and decide
logistically how LO enter patients' wishes
into their medical records LOcomply with
the PSDA. HCFA is responsible for writ-

ing the terms of the law into regulations ,
In regulations scheduled to have been
issued in October , HCFA was expected to
specify how providers should comply,vith
the law for patients who are unconscious
at the time of admission as well as define
exactly when hospitals should give patients information about patient rights
laws - before a planned hospital admission, at the registration desk or at the
patient's room.
Other issues related to compliance with
the law may be more difficult to solve.
The PSDA spotlights the difficulties of
obtaining truly tnfonned consent, says
Susan Goldberg, ofMagavem &amp; Magavem,

medical treatment so it's harder for them
to prove they're competent LO make a
decision. There are an awful lot of people
out there without the documentation and
without families to speak on their behalf."
In New York State, the Patient SelfDetermination Act will likely ensure that
hospitals now routinely ask patients
whether they have living wills LOenter into
theu records. Buffalo area hospital administTators say they \viii continue and
improve their ei,.,isting educational programs on patients rights for health care
staff, incoming patients and the community at large.
These educational efforts will focus
mostly on two New
York State laws:
• The Do Not Resuscitate Act of 1988,
referred LO the DNR
law, which mandates
that on admission all
patients receive information on how to place
their wishes regarding
CPR and other "heroic
measures " to resuscitate them in their medical records.
• The Health Care
Proxy Law, effective
January 1991, which requires that all patients
receive at the time of
admission a form and
explanation for how to
designate a proi,.,-yor surrogate decisionmaker LO gu ide their medical care when
they can no longer express their own
wishes .
These laws have already been gradually, a~d occasionally grudgingly, integrated imo hospital procedures. Peter
D'Arrigo, M.D., vice president of medical
affairs at Millard Fillmore Hospitals , recalls that when the DNR law took effect,
doctors disliked discussing it with patients who needed sunple medical procedures such as having a mole removed.
Some patients became alarmed that medical care would be withdrawn unnecessarily or that their health problems were
more due than they believed. The proxy

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legal counsel to Buffalo General Hospital.
"There 's risk - particularly with living
wills - that a person may sign a form
entitled "living Will" and not have really
understood what it might mean in a given
situation. Sometimes a fonn may give
duections that are ambiguous , and people
should not sign them without first discussing the contents with their physicians. "
Beaufort Williams, an attorney and director of Legal Services for the Elder ly in
Buffalo, is frequently appointed to represent patients who cannot adequately express their wishes. He shares a similar
concern . "Poor and uneducated people
can't always articulate their objections to

AND

BIOMEDICAL

SCIENTIST

AUTUMN

I

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1

�law was more readily underst0od.
But the burden of making medical
choices can weigh heavily on prox'Ydecision-makers who now must make decisions on their own that were once made
solely by physicians , observes Michael
Noe, M.D., clinical assistant professor of
medicine and social and preventive medicine and senior vice president of professional affairs and medical director of Buffalo General Hospital.
"The burden of suffering in cenain
circumstances appears to be so great that
withdrawa l of treatment - and we're not
talkingaboutassisted suicide- may seem
to be the only acceptable alternative," he
says. "Before proxy law, certain of these
decisions could be handled by a doctor
with perhaps a broader, more objective
assessment of the medical issues." Hospital ethics committees often help proxy
decision-makers who request additional
legal, medical and ethical guidance.
BGH's nursing, social work and medi-

cal staffs are trained to discuss pro&gt;..')'
forms
with patients. But the hospital strongly
advises that patients discuss DNR forms,
advance medical directives and living wills
with their own physicians. "The types of
decisions a patient has to make require an
opportunity to have questions answered
by a medical person familiar \vith their
situation," says Noe.
Medical professionals also mentioned a
common misconception that educational
efforts mandated by the PSDA may help
correct: many patients don't realize that
the living will is legally recognized in New
York State most frequemly when it is
accompanied by a proxy or DNR document, and it may not have a binding effect
on a particular decision about medical
treatment on its own.
Stephen Wear, Ph.D., a UB professor
who specializes in medical ethics, says,
"The real issue people have to explore is
the complexity of care for people with
chronic degenerative diseases or critical

Most medicalethicists believeNew York State's patients' rights
laws, especially the health care proxy act, are best applied
when physicians discuss them with patients as a matter of
course, beforea hospitalization or crisis. Doing so can prevent
the problems illustrated by the following recent casefrom a
local fwspital.
man in his 80s suffers a heart attack
while watching a Bills game this fall.
911 is called and he is resuscitated at
home and taken to the emergency
__ ...___ ,,__ room of a local hospital where
he is stabilized, placed on a ventilator and admitted to the
intensive care unit.
Subsequently it is found that the patient has suffered
severe brain damage. Among other things, he cannot
breathe for himself. When he is diagnosed in a persistent
vegetative state, the patient 's ·wifeand adult children unanimously request that all treatment be stopped, including
withdrawal of the ventilator.
The physician asks the family whether the patient had
made any prior statements while competent about what he
wou ld or wouldn 't want in such a circumstance. They

8UFF'ALO

PHYSICIAN

ANO

BIOMEDICAL

illness. What does their remaining time
look like, how should their care be managed?" Physicians should discuss with
their patients exactly how the proxy, living will, DNR and advance medical directive forms are used in conjunction with
each other and also how statements on
these forms about specific medical procedures would shape the medical response to theirown specific situation, he
notes.
The PSDA, by tluowing the spotlight
on state patient rights laws, is a strong
indication , at least, that patients need no
longer rely passively on the decisions of
medical providers. Clearly, patient rights
laws vary greatly from state to state. By
providing patients with information about
these laws, the PSDA takes a giant step
toward helping patients retain control over
their medical destinies - even in an era
when medical technology has redefined
the very nature of death and the process
+
of dying.

respond that although he had never talked about it specifically, they are certain he wouldn't want aggressive medical
intervention given his prognosis. The physician advises the
family that without the patient's prior competent statements supporting the withdrawal of the ventilator and
without an appointed health care proxy to make such
decisions on his behalf, this couldn't legally be permitted.
The family is aghast.
The patient remains in the intensive care unit for several
weeks and dies of a second cardiac arrest.
Under two recent New York State laws, the Health Care
Proxy law and the Do Not Resuscitate law, this patiem 's
wishes, if clarified in advance, would have been protected.
However, he had not appointed a health care proxy who
could decide about treatment ifhe lost the ability to decide
for himself. The prox y could have requested the removal of
the ventilator. The Do Not Resuscitate law would have
protected the family's right to decide whether ventilation
could be used to resuscitate the hospitalized pati ent in an
emergency but not whether ventilation could be used to
keep the patiem alive.
A UB professor of medical ethics who attends meetings
of num ero us Buffalo hospital ethics committees says such
heart-wrenching circumstances are not uncommon and
that doctors are learning through these situations the importance of explaining these laws to their patients well in
+
advance of a medical crisis.

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Always prized, an acceptance from UB's School of Medicine and
Biomedical Sciences is more sought after than ever by today 's
medical school hopefuls. "The combination of the med school's
growing national reputation and its affordability are making UB
the school of first choice for most candidates we accept, "
according to Thomas Guttuso, M.D. , assistant dean and director
of medical admissions. "The class of l 995 's rate of 1.9 acceptan ­
ces per seat is the lowest since the early 70s when the medical
school applicant pool peaked.

That means that today more

applicants accepted are saying yes to UB."
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�Maria Bruno, a first-year medical student with a 8.5. in genetics from Purdue,
has a long list of reasons for returning to
her hometown to sLUdymedicine at UB.
"I was impressed with a lot of the things
SUNY Buffalo had to offer over higherranked schools," Bruno said.
Guttusso points to favorable national
rankings as one of the key factors that
favorably disposes applicants toward UB.
"We're rated the best of the SUNY med
schools by The Gounnan Report , which is
considered the leading independent 'authority ' evaluating American medical

BUF'F

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PHYSICIAN

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schools. Nationally, Counnan ranks UB
30 out of 126 medical schools, pulling
us in the top 25 percent of American med
schoo ls." Guttusso also cites a recent
ranking by the Association of American
Medical Colleges (AAMC) placingUBas
third among all U.S. medical schoo ls
based on the AAMC's current institutional goals.
Making UB even more attractive to
prospective medical students is the
school's track record in placing seniors
in their preferred residencies. According to Guttusso, 90 percent of UB medi-

810M£0lCAL

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cal school grads are currently placed in
one of their first three choices, 15 percent to 20 percent above national averages.
For first-year student Lew Foulke, a
better chance at a prime residency was
the deciding factor for coming to UB
medical schoo l, despite the location of
another school closer to his roots in
Central New York. "Of the three schools
I was seriously considering, UB's reputation and ranking were the best, which
will give me an edge when applying for
residencies in whatever my chosen spe-

AUTUMN

1

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41)

�cialty turns out to be."
Cost, boLh from the standpoint of
tuition and area cost of living, also gives
a boost to UB's stature among medical
school applicants. Tuition for in-slate
residents is just over 57,100 which compares to a national average of about
$16,000 for public and private medical
schools; the most expensive schools
charge over $20,000annually. Thecostconsciousness of most medical students
has typically been raised by four years of
undergraduate education, often at much
more expensive private schools.
Lara Akinbami, a Harvard University
economics graduate is typical of this
breed of student, but her career aspirations in medicine also moved her toward
puuing even more emphasis on the cost
of a medical education. "Having spent
two years with the World Bank in Washington , D.C., my interests are in the
public polic y of medicine , particularly in
the areas of access and affordability,"
Akinbami said. "Since this isn't the most
lucrative venue to take in the medical
field, it made good sense to go with a very
good school that was also affordable."
Not surprisingly, being one of the
country's best and most affordable medical schools is making the admission process for UB even more selective.
Guuusso, who chairs the Admissions
Committee noted, 'The Class of 1995
was the most difficult class to be accepted into in almost twenty years. 263
applicants were accepted this year; that 's
the lowest number since 1974." About
one in 10 applicants was accepted to the
Class of 1995.
Given the difficulty of geuing in , how
does the Admissions Commiuee make
its acceptance decisions? "Obviously,
we're seeking people who are talented
academically with ability demonstrated
by both grades and MCAT scores," said
GutLuso. "We also look for the personal
qualities that are important for future
physicians: awareness of problems in the
profession, concern and empathy for their
fellow man, the commitment to being a
doctor. The final decisions are a balance
of all these factors."
The overall demographic composition of this year's first-year class hasn 't

a,

BUFFALO

PHYSICIAN

radically shifted since the mid-70s when
the medical school first started tracking
a wider range of student statistics.
Women and minorities continue Lobe
well-represented,
renecting
the
University"s early commitment in this
area. Over the years, the average age of
the first year medical student has increased to 23.5 years from a low of 22.1
years in 1976. The class of 1995 has 22
people over 25 years old, indicative of a
growing national trend for medical students to pursue other work and academic interests before entering medicine.
Darren Caparaso,a 25-year-old Western New York native, who majored in

VitalStatistics:
Theclassof1995
'

Applicants
................................... 2693
S18
Interviewed..................................

Accepted
....................................... 263
ClassSize...............13SMedical
School
...................................
4 MST
Program
Average
Age............................... 23.S
Men............................................... 79
Women
...........................................S6
Science
Majors
..............................
100
Non-Sci
enceMajors
.........................3S

business at UB as an undergraduate and
completed a masters in biology from
Buffalo Stale College, credits his work
experience in a variety of hospital positions with his decision LO become a doctor. "Wor king in a hospital for several
years helped me to focus in on medicine
as a career. Being a first-hand observer
of what goes on in a hospital environmem also gave me the confidence to
know that medicine is the right choice
for me. "
Although academic performance as
measured by GPAs and MCAT scores
hasn 't changed significantly, one noteworthy change has been a marked increase in the number of non-science
majors, 35 in this year's first-year class.

ANO

SIOMC:OtCAL

SCIENTIST'

Gullusso explained, "More than any one
particular major, we're looking for demonstrated academic excellence along with
leadership, compassion and exposure to
the medical field. This gives students
the opportunity to get a broader undergraduate education. Of course, to be
admitted, non-science majors must fulfill core science requirements and perform well on the MCATs."
Foulke, who studied the classics in
college and worked in a hospital environment before medical school, explains
the seeming discrepancy in his undergraduate and post-graduate fields of
study. "I was drawn to medicine by an
interest in the growing body of research
showing a defin ite mind-body connection which affects personal hea lth. Because I was strong in the sciences during
high school, I opted for a non-science
major to improve and develop my verbal
skills."
Regardless of how favorably the Admissions Committee is impressed by the
quality of candidates interviewed, the
size of the first year class remains constant, having been set at 135 in 1971.
Additionally, a maximum of five applicants are admitted to the Medical Scientist Training Program which prepares
student for careers in academic medicine as well as medical practice.
Guttusso, involved in UB medical
school admissions for 16 years, noted
that the number of applicants to medical
schools has dropped dramatically from
the early 70s at UB from a high of over
5,300 in 1974 to approximately 2,700 in
1990. "l think today 's applicants are
very aware of the negatives affecting the
general atmosphere in medicine: malpractice, government intervention and
control over income and the AIDS crisis," Guuuso said.
"Co nsequently, applications have
fallen off from the early 70s, when.many
students viewed medicine as a career for
those smart in science to make a lot of
money. I see this as a blessing because
every applicant we're now evaluating is
really com mined to being a doctor for all
the right reasons. Ultimately, that 's a
positive trend for the medical school and
+
the profession."

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Dartmouth
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HamiltonCollege

Univer:sily
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longIslandUniversity

CornellUniversily

Scienceand
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ErikJonStumpf
Chemistry

Wng TsangTong

Rolph!Patrick
Tufano

Chemistry

Biology

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HamiltonCollege

SUNYat Binghamton

TimothyE.Von Duzer
, Chemistry
BrighamYoong

DennisDorrWeimer, Jr.

EllenMorie Whyte

Biology

Biochemistry

ConisiusCollege

Universilyof Chicago•

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Andrew
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Bi(?logy

Biology

Biology

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HofstraUniversily

Wendy LynnWeinstein LorraineS. Williams
Biology ,
Psychology

CornellUniversily

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Universily
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SUNYat Binghamton

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o the best of his knowledge,
which
is considerable,
Balamurali Ambati, age 14, is
the youngest medical student
in the history of American medical education. A memberof the
Class of 1995, Ambati was accepted at 13 to the medical
sc hool 's Medical Scientist
Training Program (MSTP),
which on completion simultaneously awards M.D. and Ph.D. degrees.
In discussing the historic acceptance,
Thomas Guttusso, M.D., who heads admissions for the medical school said, "We
believe that Ambati is the youngest ever
admitted anywhere, certainly at UB. His
application came to us through normal
channels and his credentials were excellt:nc. Actually, the academic record for
MSTP applicants must be outstanding;
admission standards are more rigorous
than those for applicants only applying to
the graduate or medical school."
He
added that the one major consideration
given to age was that the MSTP program
takes seven years which would make
Ambati about 20 years old at graduation.
But although Ambati's age makes him
distinctive, Guuusso said he will receive
no special support. "Because the medical
school strives to give a high level of support to all students, I'd expect no more
than we give other incoming students. His
ability to graduate from college with honors in two years is an excellent indicator
that no extra support will be needed."
Ambati, who modestly acknowledges
the recognition and nurturing of his talents he received at an early age, is also
quick to point out that a lot of hard work
has contr ibut ed to th e considerable

BUF"l"ALO

PHYSICIAN

AND

achievements of his short lifteime. A
magna cum laude graduate in biology
from New York University (NYU), Ambati
was on the dean's list throughout his short
tenure at NYUand made USAToday'sAllUSA Academic 2nd Team. He plans to
pursue both research in neuroscience and
a medical speciality in ophthalmology.
In addition to his academic successes,
Ambati has also coauthored AIDS: The
TrueStory, a book primarily aimed at high

B

IOMEDICAL

SCIENTIST

school students, wh ich examines the epidemiology, treatment and ethics of the
disease. His collaborator on this project
was his brother ,Jayakrishna, who started
medical school at 17 and is now in the
fourth year of an M.D./Ph.D. program at
another school.
For hls pan, UB's Ambati, on an even
faster track, is now on his way to becoming
the youngest doctor in the United States. +
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�PRESCRIPTION

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5 C O T T

PAIN

:

T H O M A S

f all the symptoms that physicians

are presented with, pain is the one that troubles the most patients and can be the
most perplexing to treat.

►

Reliable estimates say that one in three Americans

suffers from some form of chronic pain - pain that persists long after its useful
function as a warning sign has passed. Half of them will become disabled for
days, weeks or longer.
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�f pain were a disease, it would be an epidemic.
But, of course, it's a symptom with literally
dozens of diagnoses. Headache and backache
top the list of the most common complaints.
Pain also intrudes in the lives of people with
arthritis, sciatica, degenerative spine disease ,
peripheral nerve damage, stroke, shingles and
whiplash. And people with cane.er must cope
with managing pain which, if left unchecked
in the disease 's advanced stages, can be the
most excruciating agony known to mankind.
Increasingly , physicians in all specializat ions are recognizing pain for what it is: an insidious invader that works in
a thousand ways to not only destroy their patients ' quality of
life, but affect their physical well-being as well. And throughout the medical field, there's a new awareness that pain,
unlike its root causes, nearly always can be controlled.
"Up unt il the last decade or so, doctors were more focused
on cure rather than care," says Mark. J. Lema, M.D. , who
directs the Department of Anesthesiology at Roswell Park
Cancer Institute. Lema , an assistant professor at UB's School
of Medicine and Biomedical Sciences, is director of anesthesia research for the school's Department of Anesthesiology.
"The body 's nervous system is the last medical frontier to
discover, " Lema says. "One engram [a nerve bundle in the
brain that serves as a switching area for pain I is more
complicated than the most complex microchip. "
Increasing the difficulty of assessing and treating pain is
the problem of measuring an individual's pain. By its very
nature , pain is subjective; what one person feels as a minor
irritant, another might experience as an agony. Factors as
diverse as individual biochemistry and cultural differences
all affect what pain feels like and how it is tolerated.
"There 's a sociocultural aspect to it - how does one
respond to pain? - that 's built up in the early stages of life/
says Romanth Waghmarae, M. D., assistant clinical professor
at the medical school and director of pain management
programs at Sheehan Memorial Hospital and Kenmore Mercy
Hospital. "In certain cultures, children are taught to be stoic,
to 'tough it out'; in others, it's considered acceptable to Cl)'
and wail and really feel it."
Research has shown that Americans of Mediterranean
heritage feel pain more deeply than their neighbors whose
ancestors were Northern European. And it's widely acknowledged that most women have a higher tolerance for pain
than most men, perhaps a blessing that toughens them for
childbirth.
But individuals' pain tolerances vary widely, even within
families. The reasons remain a mystery of biology .
Pain specialists, or algologists, sometimes use a simple
10-pointscale, asking patients to rate theirown pain. Though
this doesn't make it any easier tO compare the experiences
of different patients , it helps in assessing an individual

ED

BUFFA

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PMVStCIAN

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B10Mco1cAL

patient's progress during treaunent.
The biochemistry of pain is simple enough: injured nerve
cells transmit a "pain signal" to the dorsal horn of the spinal
column. The signal is then relayed through the spinal cord to
the thalamus, the pan of the brain that recognizes the
impulses as pain.
For people suffering chronic pain, though , the ordeal goes
far beyond chemistry. They may find themselves in a vicious
circle of tension , anxiety and further pain.
Waghmarae says pain works subtly to disrupt the fabric of
relationships, avocations and habits that make up daily life.
It becomes a constant, an uninvited companion that causes
people to function on a lower level. It is always present; even
sleep doesn't bring relief.
"You suddenly become abnormal," Waghmarae explains.
"That in itself works against you." People who become
disabled may develop a whole range of sympt0ms related t0
the pain that put them out of work.
These people may snap at their spouses and children partly from frusuation, partly from edginess related to the
pain itself. They might go out less , insulating themselves
from any activity that might increase their pain.
Their relationships suffer. They become sedentary, causing even more med ical problems , increasing the pain. Depression follows - and so on and on. After a wh ile, pain is
only one part of a complex of misery that it has caused.
"It changes your life," says Vivian Schiferle, a Town of
Tonawanda woman who suffered wiLh chronic pain after a
back injury several years ago. "I couldn't think because of the
pain.
"It's the liule things that change. The way you dress. You
have LO learn LO like low nat shoes. Even· to go out to dinner,
we would go where the chairs were good. We wouldn't go
where maybe the atmosphere was terrific, or to that new place
that jusl opened. It was always where the chairs were comfortable."
Schiferle's pain has been controlled for over a year now,
Lhanks to severa l epidural injections of steroids, a relalively
recent innovat ion in pain therapy generally used for cancer
and other severe, debilitating pain . In this procedure , an
analgesic mixture - most often narcotics or steroids - is
injected into the epidural space in the spinal column, deadening Lhe sensation by blocking transmission of the pain
impulses.
In recognition of pain asa distinctentity , treatable in itself,
physicians and hospitals have begun to establish pain management programs. The goal is not only to eliminate patients '
pain as much as possible, but to teach Lhem how Lohave full
lives despite pain that won't go away.
One such program is the pain managem~nt center at
Buffalo General Hospital. 1ts medical director, Gerald L. Peer,
M.D., is a clinical assistant professor in the medical school's
Department of Anesthesiology.

SctCNTIST

AUTUMN

1991

�ln addition, there are physical benefits. It has been re"It's very individualized," Peer says of the Buffalo General
ported
that patients who use PCA after thoracic surgery or
program and others like il. "We tailor-make the treatment for
repair
of
broken ribs are more likely to breathe deeply each pat ien L"
reducing
the risk of pneumonia - because their chest pain
Peer says such programs may involve not on ly physicians ,
is better comrolled.
but also psychotherapists, occupational therapists, social
"Pain and suffering is second only to incurability when
workers and nurses who specialize in pain managemenl.
people
think of cancer," says Lema, whose practice deals
"Many times, " he says, "we can tell a patient that the pain is
largely
with
cancer pain. "It's not even the prospect of dying
no longer a sign of ongoing physical damage . The:n we find
that
scares
[patients]
so much as the thought of suffering."
the best ways we can to help him live with it. " The solutions
With
some
cancers,
such as leukemia, the patient's pain is
may be as simple as help ing the patient to arrange for
relatively
mild.
But
Lema
says tissue cancers often encroach
ho usehold help, or adjusting his medications , or fining him
on nerves and bone , sparking constant and debilitating pain.
with a body brace to take the pressure off the afflicted area.
In addition, he says, cancer treatments - chemotherapy,
The multifaceted approach of pain management programs
radiation therapy and surgery
is being [eltat the medi - all bear their own costs in
cal school as well, says
severe pain.
Robertj. Schuder, M.D.,
Epidural mJections, he
interim chair and assosays,
work "much of the
ciate professor in the Detime ." But until repartment of Anesthes iolcently,
physicians
ogy.
shied away from prescribing
"We're a pan
these opiates, fearing that
of the team, " Schuder
patients
would become
.,
:says of anesthesiologists.
addicted.
~
"We serve as a buffer be::::"'-..
~,;:;~
For those in end-stage
~
-:.:::::: .:::,
tween the an of medicine
: :::
cancer,
it's a moot point.
-:.:.~ '
and the technology of
But
even
for patients with
·• '· :
medicine.
less advanced cancer, or
"And we bring some
those with non-malignant
humanity to it. You can
chronic pain, studies have
not on ly do [the job I, you
shown that narcotics taken
can empathize as well. "
only to relieve pain are
Schude r says residents
highly unlikely to result in
in anesthesiology deal with
addiction.
a variety of acute and
"It's very awkward some,·
,: -- .....
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..: .• ,,
chronic pain situations in
' ...:.·/~/ ~/
times,
because we have a
' ,,.,.
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their work at Western New
• , , ... II\\'
=
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war
on
drugs right now, "
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Lema says. ''Peoplearesayhospitals. There,
to drugs .' Well , there 's a small minority of us
ing,
'.just
say
no
he says, they are often exposed to what has been ,called the
who are saying, 'Let's say yes to drugs when it's appropriate. "'
most exciting innovation in pain management in decades:
All sons of alternative therapies are availab le as well, from
patient-controlled analgesia, or PCA.
the
widely accepted to the marginal. Besides the holistic
Patient-controlled analgesia is most often used for postremedies some sufferers swear by - hypnosis, massage and
operative patients , people who otherwise would depend on
acupuncture
among them - one frequently prescribed treata nurse and a needle for relief of their acute pain. With PCA,
ment
is
transcutaneous
electrical nerve stimulation, or TENS.
patients regulate their own pain. By pushing a button on a
This
hand-held
device
delivers
a m ild electric shock directly
specialized pump, they self-administer an analgesi,c through
to
the
afflicted
area,
affording
relief by interrupting the
an intravenous line.
nervou
s
system's
"pain
circuit.''
Studies have shown that patients on PCA use less pain
"The fact that you have pain limits you," Waghmarae says .
medication - and receive bener pain relief - than those
"No
matter how hard you ti)' to be normal, your behavior
who must request a shot. Patient-controlled analgesia
changes.
" For the patient , he says, the questio n is simple:
also gives patiems a greater feeling of autonomy and involve"How
do
you manag e?" The answer, as physicians know all
mem in their recovery- invaluable psycho logical assets as
+
too well, takes a little mor e consideration.
they heal.

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year, except for the major holidays, " he
explained. "We really have an overabundance of student enthusiasm for
the projecL."
The attitude of the students is "fantastic" according to Juanita Hunter, pro fessor of undergraduate nurse education, project director for the Nursing
Center for the Homeless and coordinator of the clinic. "It must be understood
that the students generated the idea and
did all the work to get it established," she
explained. "This situation provides a
great opportunity for the students to
understand how health care should be
provided to such less-fortunate groups

Medstudents
establsh
"Hope
Clinic"
attheOtyMission
STUDENTS

JOIN

NURSING

CENTER

group of enthusiastic UB medical
students has joined with the
University's Nursing Center for
the Homeless to provide extended medical care for the less
fortunate of Buffalo. The "Hope
Clinic," which meets every Saturday

EI)

BU

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PHYSICIAN

FOR THE

H OMELESS

morning at the City Mission, has met
with great student enthusiasm, according to, Joseph D. Kay, a second year
medical student and co-director of the
medical student contingent of the clinic.
"We're working on a rotating basis. Four
of us work every Saturday during the

ANO

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in our society."
The ursing Center for the Homeless, a federally funded non-profit organization, was established by Hunter in
1988 to provide free nursing care for the
homeless. The medical students, she
explained, began organizing two years
ago under the direction of Kayand fourthyear student Geraldine Rubin, third-year
students Alissa Shulman, Kristen Paulus
and Anne Comi and second-year studentjennifer Wargula. They joined the
clinic last June. "The advantage of having a medical clinic to go along with the
nursing program is that if you have a
person who needs to cons ult with someone who has greater medical expertise,
you can refer them to the Hope Clinic."
The results have been encouraging so
far, but it wasn't easy getting all the
pieces in place to make the operation a
success, said Kay. ''Our major stumbling block was recruiting community
doctors who would volunteer to work
for a few hours on a Saturday morning,"
he exp lained. "We wouldn't be able to
do what we do here without a licensed
M.D. present."
Kay explained that any physician who
wants 10 be a part of the program simpl y
needs to obtain an adjunct appointment
from th e medical school. "And that 's not
difficult to obtain. With that, the doctor
is covered by UB insurance. "
Anthony Bartholomew, a professor at
UB's medical school, said that the camaraderie established between the stud ents
will be beneficial to them in the future.
"I give them a lot of credit. It's great to
see first and second year medical students working with senior students to
care for patients. They've really made
this work."
Fourth year medical student Patricia
Reddin said that the clients at Hope
Clinic present unique problems for the
stude n ts and doctors. "You see a very
different population here from week 10

..

BUF

fl"ALO

PHVStCJAN

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w e e k .

There a re
often immigrants who
have Iit tie
command
of the language and
that is difficu It," she
said while
preparing to
question a
40 year-old
woman
from Somalia who had never seen a doctor in her
life and was complaining of a non-stop
headache.
Kay said that the range of ailments
exhibited by the patients who frequent
the cliniic are numerous but often predictable, given the conditions in which
they live. "There are a lot of skin problems, especially the feet and fingers, because a lot of these people are outside a
good portion of the time. And of course
we see substance abuse cases. We've

even had a few cases of tuberculosis,
which is really scary."
Elizabeth Brown, who works for the
Nursing Center for the Homeless, said
that the program's success hinges on the
cooperation and stamina of all who take
part in it. "The students are really hungry 10 get some clinical expe rience to go
along with the theory. For the Mission,
it's simply something they've never had
before. It's really needed. And the
potential of the program is just now
unfolding.· •
Part of the cooperative process that
underlies the clinic's success lies in the
generosity of various agencies around
the city according to Kay. "We have an
agreement with the Washington Street
Pharmacy where they provide the medication at wholesale, which makes it cheap
for us. Millard Fillmore Hospital gives
us a lot of supplies that are essential here
as well.··
The Hope Clinic examines between
seven and 10 patients every Saturday,
according to Kay. "But this is as much a
learning tool for us as it is a community
service. If we can incorporate ourselves
into the medical school as a program,
they'll provide us with the stability we
+
need."
-

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1991

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'

I

Dr.James
F.Mohn
Ends
His
Distinguished
Career
atUB
A LONG

TENURE

O F TEACHING

is faLher and grandfaLher were
both opposed LoJames F. Moh n's
choice of medicine as a career.
"They Lhought I was a born
Leacher buL ever since I was a
smal l boy I wanted to be a
physician. 1 just never planned that I
would combine my medical career with
Leaching and thaL iLwould Lum into Lhe
longesL teaching span of a full-time faculLy member in the medical school's
history - 45 years and nine months
to Lhe day."
Mohn relishes recalling the smallesL
details. AfLer graduating from Fosdick
Masten Park High School, he entered Lhe
University of Buffalo - helping pay his
way th rough school by work ing in The
University's maintenance depanmenl. "I
remember I was weeding the peony bed
in front of Foster Hall when I heard that
Germany had invaded Poland."
After only two years of pre-med sLUdies, he was accepted into medical school
and during his freshman year came
under the inlluence of Professor of Bacter iology and Immunology
Ernest
Witebsky who had lled the Nazis and his
German homeland in 1936, arriving in
Buffalo three years later.
"Witebsky was th e most famous person on the staff of the medica l school, a
pioneer in immunology. He took me LO
Buffalo General Hospital and had me
ster ilize boules - he believed in learning about research from the ground up.
1 stayed with him until he died. "
While still in medical school, Mohn
contracted pulmonary tuberculosis -

e

BUFFALO

PHYSICIAN

"They thoughtI was a
born teacherbut ever

, RESEAR C H AND SER V ICE

he says he still remembers the patient
who was the source of his infection.
His internship at Buffalo Gene ral was
cut short and he entered th e Niagara
Sani tarium.
JusL before entering th e sanaLarium
he took Lime out for his wedding to one
of his med -tech sLudents. "We honeymooned on Lake Canandaigua and then
1 went into the sana tarium. It was warLimeand my wife was working at Buffalo
General as Wite bsky's chief technolo gist," Mohn recalls. While recovering
from TB he rebuilt the institution 's
diagnostic laboratory.
On Apri l 1, 1945, UB president
Samuel Capen appointed Mohn instructor in bacteriology and immunology,
officially beginn ing his teaching career.
Mohn likes to joke that he "knew all the
buildings at UB as people - Capen,
O'Brian, Crofts."
As his mentor, Witebsky imbued
Mohn with the ideals that have stayed
with him throughout his professional
career wh ich is s till ongoing despite his
retirement in January, 1991 from his
position as professor of microbiology
and directorof the Ernest Wi tebsky Center for Immunology.
"WiLebsky believed in the troika teaching, research and service as a necessity for Lhe best teaching of medical
sLUdent s," Mohn said.
Mohn 's research has taken him to
Walter Reed Army Center while on active service during Lhe Korean War and
Cambridge Universi Ly where he work ed
wiLh Professor Robin Coombs, inventor

AND

810ME01C.t.L

SCIENTIST

sinceI was a smallboy I
wantedto be a physician. Ijust never
plannedthat I would

combinemy medical
careerwith teachingand
that it would tum into
the longestteaching
span of afull-time
faculty memberin the
medicalschoolshistory."
of th e Coombs test. His blood group
research led him LO make numerous visits to Finland and LO Lhe discovery of a
new blood group variant - AFinn· ln
1988 he received the Nevanlinna
Medal from the Finnish Red Cross for
his co ntr ibuLions LO blood transfusion
services.
Mohn's expertise has been sought ou t
by state, naLional and international leaders. He was one of th e co-founders of the
International Society of Hematology,
started in Buffalo in 1948. In 1974 he
was appointed by the Governor and confirmed by the state Sen ate Lo a council
fonned to regulate statewide blood trans-

AUTUMN

199

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�. .. .... . .... .. .........

. ..... . .... . .... . .. . .. . ... .. ... ... . ... .... .. ... .. .... .. . . ...... . ..

fusion practices. I le remains chairman
of the State Council on Human Blood
and Transfusion Services and director of
Buffalo General Hospital's transfusion
service, named in honor of Witebsky.
His blood research led to an mntation to the etherlands to help celebrate
the 25th anni\'ersary of the Red Cross
BloodTransfus1onScrvicesCentral Laboraton . The court Iv and dapper Buffalo
nati\'e took tea with Queen Juliana. who
was less well -turned out than he - her
slip was showing .
But Mohn doesn't mind donning work
clothes and working as a carpenter and

Bu,-,.Al.0

PMYIICIAN

fl]

the other way. Ifwe didn't have regional
center-,. we wouldn"t be doing transplants and cardiac su rgery."
Hi!&gt;long record of Red Cross ser"ice
includes a term as Greater Buffalo Chapter chairman He is currenth chairman
of the Red Cross Medical-Scientific Advisor) Committee and the chapter fitra\'el
nancial development committee.
He ,s proud of his -f6 years of \"OlunOf all his honors and awards. though,
teer sen 1cc,, Hh the Red Cross In the
\tohn sa,d the highest mbute he ever
earl} days he ,,as opposed to the Red
came when \Vitebskv praised
Cross concept of regional blood ser- received
him the
as a teacher-calling
abilit)
nces. but soon realized the wi.sdom of his
+
known.
ever
had
best teacher he
the approach. "If you're an objective
LLIAMS
WI
DEBORAH
-BY
scientist. vou ha, c to face facts . I swung

painter to restore his 1851 Elma farmhouse,, here he and his wife raised four
children. He collects antiques and art as
well as wines and has been working
throughout the rear on another pct
project of h,s - the Red Cro-.s· \'intage
Affair-an auction ofwmes, dmingand

ANO

&amp;1O,-.iC0ICAL

$CIC:HT

t

lT

AUTUMN

1091

e

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·•····
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[i]
.

'

Firstannual
Southern
Tiersurgery
meeting
heldinOlean
hysicians and professors from
The Cleveland Clini c Founda tion, George Washington University, Hanneman University
Hospital, Buffalo General Hospital, Olean General Hospital and
the State University of New York at Buffalo School of Medicine and Biomedical
Sciences convened for the First Annual
Upda te in General Colon and Rectal
Surgery in October.
Working with chairman and program
director Adil H. Al-Humadi, M.D., adj unct clinical assistant professor at UB
and colon and rectal surgeon at Olean
General Hospital, were Eddie Hoover,
M.D., chairm an of the medical school's
Department of Surgery and Bertram
Portin, M.D., head of the Department of
Co lon and Rectal Surgery, who moderated the symposium.
Designed to apprise primary care
physicians, internists, surgeons and
health care professionals of the most
recent developments in the diagnosis

e

BUFFAL

O

PHYSIC1AN

and management of selected surgical
problems including colon and rectal surgery and gall bladder disorders, the Update was the first conference in general
colon and rectal surgery held in the
Southern Tier area. The program was
designed by the Department of Surgery
as part of its Continuing Medical Education program.
+

James
PlattWhite
Society
seeks1,000
donors

he Schoo l of Medicine and Biomedical Sciences and the James
Plan White Society have launched
a "Th ousand at a Thousand" campaign to raise funds for biomedical and clinical research, scholar ships for needy and meritorious students, state -of-the-an laboratory equip11
ment, educational p rogrammin g and unrestr icted support
for special needs
ichard S. Safeer, a second-year and opportunities.
medical student, has received an
The campaig n
award from the Regional Center was la un ched in
for Clinical Nutrition Education September, accordof The New York Academy of ing to Eugene
Beltrami , M.D. '54,
Medicine for
\\tt,'*/JJ,
James Platt White
a paper on cardio- ~\\!
Society Chairman.
vascular disease. ~The James Platt Jam
es PlattWhite
Safeer, who is~,,~
.: • ~
th eoriginatorand ~
§
White Society was formed in 1986 on
directorofthe"Get ~
~ the 140th anniversary of the founding of
Heart Smart" pro- ~/
~ the medical school to recognize dedigram, won in the Comcated alumni and friends of the medical
munity Work category. +
schoo l who contribute $1,000 annually.
The James Platt Wh ite Society provides vital financial resources to help the
medical school attract the best students,
retain top faculty and strengthen biomedical research, educational and clinical programs , Beltrami said.
James Platt White was one of the
founding members of the University at
BuffaloSchool of Medicine and Biomedical Sciences. An obstetrician and gynecologist, Wh ite contributed important
improvements in the practice and teaching of obstetrics, conducting the first
clinical demonstrations in obstetrics in
the United States and advocating anesthesia in childbirth. He was professor of
obstetrics for 35 years and dean of the
school at the time of his death in 1881.+

Safeerwinsawardfor
GetHeartSmart"
program

fll~

~

'fl//m~~

AND

BIOMEOICA-

SCIENTIST

AUTUMN

1991

�·············· · ······· · ·············· · ···· · ····· · ··· · ··········· ··· · · ············· · ····· · ·■
·

mm
I

Medical
schoolhonors
its
facuitymembers
even faculty members and six resident physicians were honored at
the annual faculty meeting of the
School of Medicine and Biomedical Sciences.
Michael A. Apicella, M.D., director of the Division of Infectious Diseases in the Department of Medicine,
received the Stockton Kimball Award
for excellence in academic achievement.
Apicella, UB professor of medicine and
microbio logy, also serves as co-director
of the UB Center for Applied Molecular
Biology and Immunology . He will deliver the Stockton Kimball Lecture at
next year's ann ual mee ting.
Jacob M. Steinhart , M.D., clinical associate professor of pediatrics, was named
recipiem of the third annual Robert S.
Berkson Memo rial Award in the Art of
Medicine. The award recognizes excellence in patient care and teaching by
volunteer faculty members.
Mary Voorhess, M.D., professor of
pediatrics, received the Dean's Award
for service to the medical school and the
University and outstanding research. Codirector of the Division of Endocrinology at The Children's Hosp ital of Buffalo, she has served on various committees of the medical school and its department of pediatrics.
Louis A. and Ruth Siegel Teaching
Awards for teaching excellence were
presented in the following categories:
pre-clinica l, Charles Severin, Ph.D., associate professor of anatom ical sciences;
clinical, Bradley Truax, M.D., clinical
associate professor of neurology, a nd
volunteer , Christopher Valencia , M.D.,
clinica l instructor of medicine.
House staff awards were presented to:
Maritza Cotto, M.D., resident physicia n
in medicine;John A. Leone, M.D., resi-

HislaAngela
Bates

UBmedical
student
winsNIMH
award
isla Angela Bates, a third-year
medical student, has been chosen one of six medical students
in the U.S. to receive an American Academy of Child and Adolescent Psychiatry James Comer
NlMH Minority Fellowship Award. She
rece ived a $3,000 stipend to support
participation in research in child and
adolescent psychiatry last summer.
Bates, under the direction of Gary
Cohen , M.D., clinical associate professor of pediatr ics and psych iatry, David
Kaye, M.D., clinical assistant professor
of psychiatry and Richard Clopper, M.D.,
clinical assistant professor of psychology and psychiatry , was involved in the
prospective psychosocial screeni ng of
children referred to the Pediatric Endo crine Clinic at Chi ldren's Hospita l for
evaluatio n of growth problems or newly
diagnosed diabetes mellitus.
The Comer Award is funded through
a grant from the National Institute of
+
Mental Health .

BUl"F'

A

LO

PH

Y

SICIAN

ANO

BIOM£01

C

AL

SC

I

ENTIST

I

dent physician in medicine; Michael
Denk , M.D., resident physician in sur gery; Frank Green, M.D., resident physician in medic ine; Nashat Rabadi, M.D.,
resident physician in medicine , and Joseph Cinderella, M.D., resident phys ician in medicine.
A special award was presented post humously toJohn F. Moran, Ph.D., asso ciate professo r of biochemistry and
former assistant to the dean for facilities
+
planning, who died in February.
B y

A R T H U R

P A G E

Schwartz
headsUB
cardiology
division
effrey S. Schwartz, M.D., has been
named chief of the Division of
Cardiology in the Department of
Medicine.
A professor of medicine at the
University at Buffalo and faculty
member since 1987, Schwartz is the
head of the Division of Cardiology at
The Buffalo General Hospital.
Prior to coming to
Buffalo, Schwartz
was associate professor of medicine
and di rector of the
exercise laboratory
at tlheUniversity of
Minnesota Medical
JeffreySchwartz
, M.D. School.
A graduate of
Rutgers Univers ity, he received his medical degree in 1968 from Albert Einstein
College of Medicine and did a cardiology
fellows hip at the University of Chicago.
He also did research on narrowi ng of the
coro nary arteries under a National Institutes of Health Young [nvestigat0r Re+
search Award.
B Y

A R T H U R

AVTU-MN

I

P

9

9

A G

1

E

6)

�Kassirer
receives
-1991

full-time people who were extraordinary teachers and doctors. The environment was very carefu lly designed for the
student. l'm sure it's even more so today .
After l had begun my career, it was
apparent to me that these great teachers
and doctors had become role models
for me."
As an acknowledged specialist in
nephrology and internal medicine,
Kassirer has received national recogn ition for his work on diagnost ic reason ing and therapeutic decision-making .
He is the Sara Murray Jordan Professor
of Medicine and vice chair of the department of medicine at Tufts Universi ty
School of Medicine, Boston, where he
has been on the facu lty since 1961.
Kassirer also is associate physicianin-chief at the New England Medical
Center, Boston . Kassirer has over 100
publications on a varie ty of aspects of
clinical medici ne. A Buffalo native, he
auended UB as an undergraduate from
1950 to 1953, entering medical school
following his junior year.
While attending medical school, he
was named to the Gibson Anatomical
Society and Alpha Omega Alpha and
received the C.V. Mosby Award and the
Roswell Park Award in Surgery. He
received his medical degree magna cum
laude, and did his internship and served
as assistant reside nt in medicine at The
Buffalo General Hospital.
Since 1986, he has served as a regiona l member of the governing board of
the UB Medical Alumni Association.
He said that his multi-faceted career
was a key factor in his securing the
editoria l duties at The New England
Joumal.
"The experiences I had in my early

Distinguished
Alumnus
Award
NEW ENGLAND
MEDICAL

J O URNAL

EDIT O R PR A ISES

UB

SCHOOL

erome P. Kassirer, M.D., editor-inchief of The New England Joumal
of Medicine, received the 1991
Distinguished Medical Alumnus
Award at a Past President's Dinner
on September 19 at the Buffalo
Club.
Kassirer replaced Arnold S. Relman,
M.D., last July as editor. He was named
following an extensive worldwide
search by a distingu ished panel of medical leaders. The New England journal is
the oldest continuously
pub lished
medical journal in the world and is
considered the nation's leading medical
research journal.
Kassirer said that a combination of
research and teaching excellence makes
UB's School of Medicine and Biomedical
Sciences one of the great academ ic centers in the country.

"Buffalo
is obviously
veryimportantto me.

It was herethatI
developedmy idealsand
my knowledgein the

field of medicine."
"Buffalo is obviously very important
to me. It was here that I developed my
ideals and my knowledge in the field of
medicine," he said. "When I was in medical school here, there was a group of

Farleft: Thoma
s Riemens
chneide
r, M.D.
,
associat
e vice president
for clinical
affairsand
associat
e dean. left: James Weerick
, M.D., Class
of 1949

Eit&gt;

BUFFALO

PHYSICIAN

ANO

BIOMEDICAL

SCIENTIST

AUTUMN

I

9

9

I

�Alumni
of theMedical
n, , '77, president
withNedraHarrisoM.D.
, celebrates
of Medicine
Journal
, M.D.,'57, editorof 11,eNewEngland
e .Kossirer
JeromP
.
Award
us
ed
the1991DistinguishAlumn
, afterreceiving
Association
her going, it was what she hadn't done
LS and said that the one fundamental
men
yet that kept her going. That reprcsentS
career, includinga lot of teaching, helped
should be held b&gt;·all docthat
al
pnnc1p
ph) ."
set me up for the Job I haYe now. I tors is to perform services ,, h1ch arc very clearly my philoso
Associauon prei
Alumn
al
interMedic
very
The
me
believe those things made
useful and good for people ~rmsull a
allydcs1gned
aspeci
ith
en,
said.
he
Kassir
sented
esung to the search commntec,
doctor. \1\ responsibility 1sto do good.
tion ofh1s
emora
in
comm
in
gjob
crystal buffalo
"I think that it is the most amazin
This 1san unparalleled opportunity LOdo
ues
colleag
and
friends
award. About 75
medicine that there 1s."
good 11·sa bit awesome to me," he said
+
were on hand to honor him.
Kassircr, who addres!&gt;cd the 145th
"Martha Graham, when she was 80,
R
E
M
H A M
M A R K
B Y
commencement of the medical school in
II wasn't the awards that kept
that
said
Ma}, made light of his own achic\"e-

BurP'A.LO

PHY.IC

I

AN

ANO

e1oiw:CDtCAL

SCICNTl•T

AUTUMN

�..........

. . .. .......................

. ............

. ............

. ........................

..

Spring
Clinical
Dayand
Reunion
Weekend
set
he MedicalAlumni Associationhas seLSaturday, April25, 1992,for its 55LhAnnual Spring
Wilensky,
ClinicalDay. KeynOLespeakerGail
direcLOrof LheHealLhCare Finance Adminisrration,will address "High Technologyand
CosLConLainrnenL
in Lhe1990s."
Reunion Classes of 1942, 1947, 1952, 1957,
1962, 1967, 1972, 1977, 1982 and 1987 will meeL
on Friday, April 24 for CockLail RecepLionsand
Saturday, April 25 for Reunion Dinners. Those
classes will be vying for the Best Attendance Trophy, won lasLyear by the Class of 1941.

CLASS OF 1942
"It's hard LO lx:lievethat 50
years have elapsedsince we
graduated./.£r'smaizethis reunion as meaningful ro us as
tl1c day we received our diplomas!"
RICHARD

AMENT,

M . 0. ,

CHAIRPERSON

CLASS OF 1957
"The more rhc merrier. It's
ce11ai11ly
tme for class reunions. Thoseof 11swho have
a1te11ded
previo11Sreunions
/mowhow mud1fm1theyare.
l l1opeall my classmatesare
pla1111i11gcocomeroour35th
,
in April '92."
SOL

M.0 ..

MESSINGER.

CO -CHAIRPERSON

CLASS OF 1947
"A long rime has passedsince
we fought rl1ebattle of High
Street. Let's relivethosedays
and share new stories at rhe
45th classreunion."
WILLIAM

M . BUKOWSKI.

M . D .• CHAIRPERSON

CLASS OF 1 952
"Comebacl110see how Buffalo, the School and your
classmates have changed in
-f0years.We needyou LOmalie
r!1isthe bestreunionof all."
NEAL

FUHR

. M . 0 .,

CO -CHAIRPERSON

"Don'tyou thinli dra1after40
yew:s&lt;ISphysiciansour whole
classought LOget cogether011
April25, '92 bac/1in B1if{alo?"
ROBERT

BAUMLER

"Dr. Sol Messingerand I are
/oohingfonvard with great
expectationsto our 35tl1reose
union. We hope that 1/1
auend the 30th
who did 1101
will 111al1e
every effort to renewoldfriendshipsandshare
with otherswhat's happened
ro them over t/1eyears."
RICHARD

MILLER.

M . 0 .,

CO -CHAIRPERSON

.

M . 0 .. CO-CHAIRPERSON

"Fony years. Ir's beena long
rime and a greatprofessional
"
career.Comea,u/ celebrate!
BURTON

5TULBERG

.

M . D .• CO-CHAIRPERSON

e

BUFFALO

PHY

S

ICIAN

A

N

0

8t0MEOICAL

SCIENTIST

AUTUMN

1

9

9

1

�.. . ....

.. ..............

CLASS

OF 1962

..............

.....

....

.......

....................

.. ............

"It's hard to believeihatfive
years have gone by. Lei'sall
gel togeiher and renew 1l1e
friendships we had. We hope
to seeyou ihis Spring."

FASANELLO,

M . 0. , CO-CHAIRPERSON
JACK

C . FISHER,

CO-CHA

OF 1 987

CLASS

"Theseare ow·vintageyears.
D011'1
miss your 30th."
SEBASTIAN

.

M . 0.,

IRPERSON

THOMAS

SMITH . M . O ..

CO-CHAIRPERSON
ALAN

BEITLER.

M . O ..

CO -CHAIRPERSON

OF 1 972

CLASS

CLASS

OF 1977

CLASS

OF 1982

"Be an activist again! Co11taC1 your f rie11ds
from rhe
classof '72 and meer them i11
Buffalo. the ci1y of chichen
wings, beef 011 wec/1 and
America's premier football
ream!"

"Fif1ee11
years liavejlow11by!
/-loware our classmatesdoing? Come to the reunion on
April 25th and find out for
yourself"

MAR TIN BRECHER.

"Fifteenyears? It can'! be!
ELIZABETH
BARLOG.
Lei'sge1 togeiherbeforea11y
M.0 .. CO -CHAIRPERSON
more lime passes.Nedraand
I loolifonvard10secingyou." "A special grce1i11g10 all of
my classmaresll'irh the hope
GREGORY
YOUNG.
M . O .,
co-CHAIRPERSON
1ha11992will seeyoubachin
Buffalofor our 10-year reunion."

M .0 ..

CO -CHAIRPERSON
PATRICIA

OUFFNER

.

M . D .. co-CHAIRPERSON

N EDRA

HARRISON.

CO-CHAIRPERSON

M.0. ,

''Tl1esepasi 10 years have
go11eby sofast and so muc/1
has happened in our lives.
Won't ii be grear 10 get 10gether with old friends and
find 0111what's been going
011?See you all al our 10ycar reunion!"

KEVIN

BARLOG,

M.D ..

CO -CHAIRPERSON

CLASS

OF 1 967

"\Ve all have a date with history. I-lopeto see you all at
our 25th re1111
io11011April
25th, 1992. Be there if you
possibly ca11
!"
JOHN

P. KELLEY

. M.O ..

CO-CHAIRPERSON
THOMAS

P. SHEEHAN.

M .0 ., CO-CHAIRPERSON

PHYSICl

A

N

A

N

D

BIOMEDICAL

SCIENTIST

A

U

T

U

M

N

I

II

9

I

E!)

�··············•·····················
[I]
'

.

NoenamedSeniorVP
at Buffalo
General
ichael F. Noe, M.D., M.P.H.,
has been appointed a senior
vice president al The Buffalo
Genera l Hospital.
A clinical assistant professor of medicine and social and preventive medicine at UB and recipienL of the
Dean's Award in recogni lion of ou tstanding service to the
medical
school,
Noe most recently
served as BGH's vice
president for professional affairs. He
will continue to be
responsible for that
deparlment whi le
also serving as the hospital's medical
director.
"He has received this appointment in
recognition of his continued outstanding contributions to this inslitution, particularly with regard to medical affairs,
the University-hospital relationship and
the improvement of quality assurance,"
according to John E. Friedlander, BGH's
president and chief executive officer. +

M

JosephChazen
M.D.
namednational
fund
drivechairman
oseph A. Chazen, M.D., has been
named National Chairman of the
University at Buffalo 1991-92 Annual Fund Drive.
The UB Annual Fund seeks support from alumni and friends across the
country for University-wide needs such
as scholarships, fellowships , classroom
and laboratory equipment, library acquisitions and unrestricted funds.

J

e,

8UFFALO

PHYSICIAN

Chazen received
his undergraduate
degree cum laude
in pharmacy from
the University at
Buffalo and medical degree from the
School of Medicine
and Biomedical Sciences. Currently he is clinical professor
of medicine at Brown University, Providence , Rhode Island, medica l director of
the Artificial Kidney Center of Rhode
Island and head of Nephrology
Associates. He also is co-director of the
Division ofRenal Diseases, Rhode Island
+
Hospital.

Milgrom
awarded
an
honorary
sciencedegree
elix Milgrom, M.D., distinguished
professorof microbiology, has been
awarded an honorary doctor of science degree from the University of
Medicine and Dentistry of New Jersey in recognition of his pioneering work
in basic and medical immunology.
Among Milgrom 's major contributions is research in
the strucLUre and
function ofanLibodies related to rheumatoid arthritis and
the mechanism of
hyperacute rejection in kidney transplants.
A native of Poland , Milgrom joined
the UB faculty in 1958 and served as
chair of the department of microbiology
from 1967 to 1985. He was previously
chair of the department of microbiology at Silesian University School of
Medicine in Zabrze and professor and
acting chair a t the University
of

F

4NO

Bt

OMEOIC

A

L

SCIENTIST

Wroclaw, both in Poland.
Milgrom's scientific contributions
have earned him the prestigious Paul
Ehrlich Prize, the Alfred Jurzykowski
Foundation Award and honorary degrees in medicine from the University of
Vienna, University of Lund (Sweden),
Unive rsity of Heidelberg and University
+
of Bergen (Norway).

Schaefer
succeeds
father
inSt.Jose~hHospital
Ophthalmology
post
aniel P. Schaefer, M.D., will succeed his father, Arthur J. Schaefer
M.D., as director of the department of ophthalmology at St. Joseph Hospital, Cheektowaga.
The younger Schaefer, a UB medical
school graduate, has been a member of
the SL.Joseph Hospital medical staff since
1986. His father
was director of ophthalmology there
since the hospital
opened its doors in
1960.
Daniel Schaefer
served his resident
training in oph thalmology al the New York Eye and Ear
Infirmary , New York City, and was appoin ted chief residem in his third year.
He served a fellowship in ophthalmic
plastic , reconstructive , orbital and lacrimal surgery at Wills Eye Hospital, Philadelphia.
A fellow of the American College of
Surgeons and the American Society of
Ophthalmic Plastic and Reconstructive
Surgery, Daniel Schaefer is a clinical
associate professor of ophthalmology
and assistant clinical professor of
+
otolaryngo logy.

D

AU

TUMN

1991

�-- --------------------

-----

--

-

--

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•

9

1

2

s

0

'27 , of

B . KUITE

GEORGE

I

Conway, New Hampsh ire, is dis ab led due to a fracture of the
spine two years ago.
L. MAXWELL

LOCKIE

'29 , is

retired and lives in Escondido,
California, where he enjoys playing bridge and meeting

new

friends.

1

9

IRVING

3

B . PERLSTEIN

Louisville,

s

0
'39 ,

Kentucky,

of

retired

from practice and teaching in
1989.

9

1

4

HAROLD

0

s

K . PALANKER

'40 ,

has been invited to become a
founding member of the Albu-

left to right:AndyandHelenCappuccino
'88, WayneWaz'88, hiswifeMarijonePetruzzi
'86, TomBellomo
'88, his
wife,Cynthia
Loya
, Loriluizi'88, Margar
et Morey'88, FrankLuzi
, '88, JamieMusiker
'87, herhusband,
Michael
Nemirov
'88.
of

ogy at the University of Texas

for children with cancer in San

Amhers t , New York, retired after

Medica l School, Houston, edited

Diego, which has now been du-

N . LUBIN

ARNOLD

'62 ,

25 1/2 years in the US Air Force

the textbook /mmwrologic Dis-

plicated and spread through-

and is now Erie County Health
Commissioner.

eases of tlte Shin, Appleton and

out California with at least six
other camps having been formed.

Lange, 1991.

I look forward to coming back

querque Academy ofSurgery. He
ROBERTA

has been retired since 1987.

GI L BERT

'62 ,

read

two papers this year: ''Toward a

PAUL

M.

GOLD F ARB

'67 ,

for our next reunion and look
forward to hearing about other

D . WHITE '40 , has been

Natural Systems View of Trans-

writes from San Diego, Califor nia, that he will be taking over as

appointed to the Monroe County,

ference" at the Midwest Sympos ium on Family Theory and
Therapy, Chicago Academy of

Pres ident of the American Can cer Society for the State of Cali-

Sciences, and "Freud, Transfer-

American Cancer Society in the

ence and Differentiation" at the

an

United States . Over the last 11

sor and cha irman of the depart-

Symposium on Differentiation at

Lawrence

years, his practice has been lim-

ment of obstetrics and gynecology at Albany Medical Center,

the Georgetown Fami ly Center,

Andover, Massachusetts, is an

ited to doing surgical oncology.

Washington D.C.

He has been a member of a

JOHN

Florida, Alliance For the Aged
Advisory Committee.
MYRON

GORDON

'48 ,

profes-

will be on sabba t ical from JanuEHRLI C H '63 ,

is now

ary 1992 to June 1992 in Lon-

FRANK

don, England, at Kings College

deputy chairman of the depart-

Hospital.

ment of surgery and director of
the division of surgical critical

1

9

F LOYD

6
H.

LIPPA

0
'61 ,

s
was

care and nutrition at the Graduate Hospital, Philadelphia , Pennsylvania.

fornia, the largest division of the

aviation medical examiner. He
also nies antique aircraft.

versity in San Diego. He is active

specialist, is di rectorof the respi-

COLE

'73

,

a

ratory department and sleep dis-

doing surveys of hospital cancer

orders center at North ridge Hos-

programs. "Of the things that l

pital in

proud ofis having started a camp

PHYSIClAN

at

Hospital ,

with the College of Surgeons

years, the one that I am most

0

surgeon

General

pulmonologist and critical care

pro-

L

'72.

JEREMY

fessorand chairman of dermatol-

A

N . WARNOCK

o rt hopedic

s

0

tained affiliation with the Uni-

ROBERT

I"'

RICHARD

7

fort he last 10 years and has main-

pital, Dearborn, Michigan.

F

9

mu ltispecia lty oncology group

three-year term at Oakwood Hos-

U

1

orthridge, California.

have done over the last several

elected chief of surge ry for a

8

members of my class ."

E . JORDON

A

H

D

'65 ,

BIOMEDICA\.

SC

ENTIST

C . S GALIA '73 , of
Hopedale, Massachusetts, is cur-

AR T HUR

AUTUMN

�■ ··························································································

I

OBITUARIES

rently vice president for medical
affairs and president of the medi-

in 1988 and became board certified in 1989. She i's now medical

Center. I have just published 'On
a Radical Lesbian

MATTHEW L. CARDEN ·19 ,

cal staff at Milford Whitinsville

direCIOr of the young adu lt t reat-

Feminist While Training in Psychiatry' in Women and Therapy.

died August 27, 1991 in Sarasota,
Florida. Dr. Carden practiced

LAWRENCE 0 . RAMUNNO'87 ,

60 years before moving lO Florida.

received an M.P.H. from Johns

While in Buffalo he served as

Regional Hospital. He maintains

ment unit for resistant patients at

a full practice in internal medi-

Four

cine/cardiology, and is a clinical
ins tructor at the University of

Westchester, New York.

Massachusetts.

JoHN

W inds

Hospital

v . Sosso

Remaining

in

medicine in Buffalo for more than

'85 . of

Hopkins and is now in private

Blauvelt, New York writes, "Re-

practice, "near a covered bridge,"

cently completed a fellowship in
allergy/immunology at Scripps

in Conway, New Hampshire.

in Health Policy and Administra-

RONALD DAVID '75 , a lecturer

chief of staff as well as president
of the staff of Mercy Hospita l. He
headed the Eric County Medical
Society in 1954. Survivors in-

tion at Harvard writes, "'I am re-

Clinic in La Jolla, California.

SUSAN L. BEHEN '88 . a fourth-

signing my post as Acting Secre-

Longing for the East Coas t , re-

year general surgery resident at

tary of Health in Pennsylvania 10

turned to open 'Orangetown Al-

Johns Hopkins Hospital writes,

clude a son, Dr. Lawrence M.
Carden of Sarasota.

return 10 academia, write a few

lergy and Asthma' in Rockland

"I will be doing a six-month fel-

JUL IUS T .

books and critically reflect on

County,

ew York. My wife

lowship at Oxford University at

died May 26, 1991. Dr. Markovitz

health and medical care in the

Oanel Piscitelli-Bosso, M.D.) and

John Radcliffe Hospital, Oxford,

had a private practice in Nonh

new millennia."

I recently had our first child,

England fromJanuary'92 toJune

Tonawanda, New York until 1955

Lauren Catherine."

'92. Any fellow alumni welcome

when he moved 10 Lauderda le-

to stop by, if you arc in the area

by-the-Sea, Florida.

DAVIDFORSTER '85 , and Carol
Hammer Forster '85 write, "We

traveling . Sorry 10have lost touch

ticed in Florida until 1980. He is

with my classmates

survived by his wife, Bernice.

friends."

cology.

arc proud to announce the birth
of our first child, Chriswpher

JAMES R . MILLER '79 , was re-

IRA L.

SALOM'77

, ofE!mhursL,

New York, has passed the first
examina tion given by the American Board of Clinical Pharma-

elected president of the New York
State Association

of County

Health Officials. He is Commis-

and old

MARKOVITZ

'28 ,

He prac-

CHARL ES R . LEONE '29 , died
May 4, 1991, in San Amonio

Brandon, on May 18, 1991. We
will be moving back to Northern

MAJOR

J OHN G . CHR IST IE
'88 was deployed LoSaudi Arabia/

while attending a mass for his

Virginia in August after two fun

Iraq/Kuwait with the 1st Infantry

deceased wife. Dr. Leone was an

years in California.

Division during Desert Storm.

auending

Carol con-

surgeon

at Saint

sionerofHealth for the Onondaga

tinues her practice as pediatri-

He is currently

in the M.P.H.

Vincent Hea lth Center in Erie,

County Health Department.

cian, and David will be practic-

Program at Johns Hopkins and

Pennsy lvania, for 40 years. He

has been selected for promotion
rank of Lieutenant Colonel.

His main civic interest for more

ing ophthalmology."

1

9

B

s

O

MIC HAEL E LLIOT CAN E '83 ,
has

a pri va Le p rac1 ice

cardiothoracic

lO

surgery

in
in

Bethlehem, Pennsylvania.

T INA

was president of the staff in 1955.
than 40 years was the Boys and

MAR IE GAR D N E R '87 ,

. writes,

Girls Club ofErie. He was a mem-

Jacob, born July 25, 1990. She is

"A large group of UB Medical

ber of the board of directors for

nowdoingou1pa1ien1 urgent care

School graduates met on the
sunny shores of Redondo Beach

over -+Oyears and in February

10 celebrate the wedding of Tom

bership. He was honored in 1983

announces

the birth of a son,

in Stony Brook, New York.

E . O STROV '83 , an
assistant professor at the Hershey

LAURA

BAR BARA

MARGAR ET MOR E Y '88

1990 was given a lifetime mem -

Bellomo '88 10 Cynthia Loya. 11

with the prestigious Silver Me-

Medical Center, Hershey, Penn-

chiatrist for Operation Concern

was a fantastic evening of cham-

dallion by the National Boys Club

sylvania, announces the birth of

pagne, fresh oysters, stir-fried
shrimp, while being serenaded

of America.

her daughter, Meredith Buckley,

in Alameda, California, writes, "I
completed my psychiatry resi-

inJu ly 1990.

dency at UCSF/Langley Porter

by a Mariachi band. Enclosed is

P OST '87 , a staff psy-

Ins1itu1e, and started a position
CAROL WEINSTEIN '84 . com-

as staff psychiatrist at a Lesbian/

pleted a residency in psychiatry

Gay Community Mental Health

~

BUFFALO

PHYSICIAN

A

N

D

BIOMEDICAL

a photo of all the Buffalo folks."

ALI CE

B E NNE TT

EMMA

MURRAY'37 ,diedjuly3l,

1989,

in Phoenix Arizona.

5C1£NTIST

A

U

T

U

M

N

1

9

9

1

��YORK

AT BUFFALO

Permit
No.311

:c _

, 5--1

L•

Ry

., €PT

�</text>
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                    <text>�...

DEARALUMNI
ANDFRIENDS,

BUFFAlD

PtIY~I~!6N
STAF
F
EXECUTIVE EDllOR
UNIVERSITY PUBLICATIONS
Ro~rt T. Marlett
BUFFALO PHYSICIAN EDllOR
Connie Oswald Stofko
AR:r DIREClOR
Alan ). Kegler

ADVISORY BOARD
Dr. John Naughton, Cluurman
Dr. Harold Brody
M, . Nancy Gheco
Dr. James Kamk1
Dr. Charles Paganelli
Mr. Gregory Zittel
Or. Antoinette Peter-s

Dr. Charle, Pruet
Dr. Luther Robinson
Dr. Thomas Rosenthal
Or. Saleda Suresh
Dr. Burton Sing~rman
Or. Stephen Spaulding
Dr. Nelson Torre
Mr. Edward Wemke
Dr. Paul W1er:b1en1ec
Dr. )trome Yates

T

he school successfully completed its institutional selfstudy on schedule in mid-June in preparation for the
November LCME survey visit.
I am graceful to the department chairmen, faculty
members, students, full-cime and voluntary faculty members,
hospital directors, and board of trustee representatives who
served on the Steering Committee and received the reports
chat emanated from every aspect of the organization. This sixmonth effort served to establish the state of the medical school
today and to develop an agenda of recommendations for casks
which should be accomplished between 1988 and the next
LCME visit in 1995.
Indeed, I chink the process proved that the medical school is strong, the faculty and
student body are committed co the achievement of scholarly excellence and meeting the
needs of society, and chat each wants the school to improve even more in the years ahead.
These are good signals chat the momentum developed over the past several years can be
maintained.
As has always been the tradition at the UB Medical School over the past 142 years,
the multiple constituencies are committed to working harder to attain higher levels of excellence. This should bode well for the upcoming accreditation visit and for our future as
we begin to think more earnestly and intently about medicine in the 21st Century.

Sincerely,
Joh n Naught on, M .D.
Vice Presidentfor Clinical Affairs
Dean, Schoolof Medicine and BiomedicalSciences

WRITERS
Li&lt;a Josephson
Clare O'Shea
Mary Beth Spma
David Snyderman
Ann Whitcher
ILL US TRATOR S
M1chad Gelen
Glyn,s Sweeny
P H OTOG RAPH ERS
Doug Levere
Dan1d Morelli
Ian Rcdmbaugh
T EAC HI N G H OS PI TALS
Batavia Veterans Admini~rrat1on

Medical Center
Buffalo General
Buffalo VeteransAdmm1'-trat1on
Medical Center
Children's
Enc County Medical Center
Mercy
Millard Fillmore
Roswell Park Memorial lnsraute
Sisters of Chamy

Produced~ rhe Di&lt;is,onof Um, en1h Relationsm as.&lt;OCUUwn
u:,rh,he Schoolof Medirine
and BiomedicalSc,ence.s,Suu, Uni,m,r, of
Nru Yorkat Buffalo.
THE BUFFALO PHYSICIAN ANO BIOMEDICAL SCIENTIST (USPS 551-860)
Autumn 1988, Volume 22, Number 3.
Published five 11mes annually: Spring,
Summer, Autumn, Early \\'inter, and Late

Winter - by the School of Med,cine and
Biomedical Sciences, Stare Univermy of
1':ew York a, Buffalo, 3435 Mam Street,
Buffalo, New York 14214.Third class bulk
postage pmd at Buffalo, New York. Send
address changes to THE BUFFALO
PHYSICIAN
AND BIOMEDICAL
SCIENTIST. 146 C.F.S. Addiuon, 3435
Main Sm,et, Buffalo, New York 14214.
Cove r Ph o to: Danit! Mon:11,

DEAR
FELLOW
ALUMNI/
ALUMNAE:

T

his is the time of year when the Alumni Board develops
the program for next year's Spring Clinical Day. Dr.
Nedra Harrison is working with her committee on an
excellent program for our scientific day, and Dr. Joseph Kunz
is working with the reunion class chairmen to gee their plan5
set for their class reunions.
Again this year, l will try to keep you abreast of the happenings on and about the Unive rsity through our newsletter, and I remain open to any suggestions you may have. In
conjunction w1ch the dean's office, we are crying co establish
an award for a distinguished alumnus of our University this
year, and plans are being sec forth with the committee to select
such an individual. If you have any suggestions as co a distinguished alumnus of our University, please forward the name with a brief biography of the person to myself, Dr. Jack Richert
or the dean's office so that person can be brought into consideration.
As this year seems to continue co slip by, I can only look forward co my 15th reunion
this coming May, and I hope that the members of my class will be active and participate
in this reunion celebration.

Sincere/),

Paul H . Wier zbieni ec, M .D.

�Vol. 22, No. 3

Autumn 1988

Features
2 East Meets West. Emerging from years of isolation, China is
reaching out to improve the medical care of its one billion inhabitants.
Under a new exchange agreement, scholars from Beijing study
Western techniques here while Buffalonians learn about Chinese
techniques such as acupuncture.

Page24

10 Medicineandthe Arts.The creativi ty of health-care professionals
was the topic of a summer symposium organized by the UB Health
Sciences Library.
14 TykeTrike
. The colorful tricycle that six-year-old Sarah Tangelder
rides has been modified by UB researchers to give electrical stimula­
tion therapy to her paralyzed legs.

Departments

Page 10

18 Research.The latest developments in organ transplantation and
a new test to diagnose celiac disease were discussed at the 11th Inter­
national Convocation on Immunology sponsored by the Ernest
Witebsky Center for Immunology.
21 Classnotes
.

MedicalSchool.Suk Ki Hong, M.D., discussed his "Thirty Years
Underwater" when he gave the Stockton Kimball Lecture at the An­
nual Faculty Meeting. This year's winner of the Stockton Kimball
Award was John R. Border, M.0.

24

31 People.

Page22

32

Alumni
. News of the reunions.

36

Events.

�2

hinese
B y

CONNIE

edicine
OSWALD

STOFKO

raditional Chinese medicine has been largely
ignored by the west, but seeing it practiced in
Beijing has piqued the interest of a group from Buffalo who
visited China in March.
'~nything that's been going on for thousands of years
must have some usefulness;' reasoned James M. Schlehr, a
medical student who made the trip.
Veronique James, another student, wou ld like to return
to China to learn acupuncture after she finishes her residency
in pediatrics.
"It may be very useful in my practice;' she said.
The two students were part of a group that spent a
month in Beijing as a precursor to a new formal exchange
agreement
among
UB,
Millard Fillmore Hospital,
and the Capital Institute of
Medicine of Beijing.
Other members of the
delegation
were Daniel
Morelli, M.D., vice chairman
of the Department of Family
AUTUMN 1988

BUFFALOPHYSICIANAND BIOMEDICALSCIENTIST

��4

Medicine at UB and director of the
residency program at Millard Fillmore
Hospital; William M. Healy, M.D., then
a resident in internal medicine at Millard
Fillmore Hospital, and medical students
Ira Rock, Jerry Igoe, Charles Everett, and
Wayne Waz.
For treating chronic conditions like
arthritis or curing the common cold,
Chinese traditional medicine does as well
as Western medicine, Waz said. He add­
ed chat there's a push in China to find
which of the traditional techniques have
a good scientific basis and which ones
seem to work only because of a placebo
effect.

AUTUMN 1988

Waz has good feelings about one tradi­
tional technique, acupuncture. Because
he once damaged the cartilage in his
knee, it aches when he walks on it a lot.
While in Beijing, he tried acupuncture
and found it got rid of the pain for three
or four hours.
While it may offer good pain relief,
acupuncture is no longer used in China
as an anesthetic for surgery because it's
not a good muscle relaxant, noted Hea­
ly, the resident.
The herbal medicines hold promise,
but even the Chinese admit that it's
sometimes hard co get as true a dose with
their herbal teas as we do with our pills,

said Healy, who has long been interested
in folk medicine. Sometimes a batch of
tea will lower blood pressure well, but the
next batch will not.
Another traditional technique is cup­
ping. The group saw the treatment per­
formed on a woman with shoulder
problems.
A lighted alcohol wick is inserted in­
to what looks like a small, glass goldfish
bowl. When the air inside the glass is
heated, the wick is removed and the glass
quickly placed on the patient's skin. A
vacuum is formed and sucks the skin in­
to the glass, forming a nasty mark that
can best be described as a giant hickey.

BUFFALOPHYSICIANAND BIOMEDICALSClENTIST

�hina's practice of med•
icine is as
distinctive as its architecture. Physicians con/ er over
medical
records
penned in traditional
Chinese
characters,
lef~
while a patient re•
ceives acupuncture
enhanced by elec •
trical
current,
below.

The technique is believed to draw harmful substances out of the body.
Traditional Chinese massage uses
manipulation to relieve pain and restore
function. Massage is used for ailments
such as arthritis.
Because they were in China such a
short time, the Buffalo visitors saw
techniques being used, but don't know
if they provided lasting results. But the
patients generally reported feeling better
initially, Healy said.

B

oth traditional and Western styles
of medicine are used in the hospitals in Beijing, and patients don't see

BUFFAID PHYSICIANAND BIOMEDICALSCIENTIST

saving?" Healy questioned.
The Chinese doctors read western
medical journals and are up on the latest
techniques. But they can't use many of
those techniques because they just don't
have the resources.
Needles, syringes, IV tubes, and
surgical gloves are washed and reused.
Before surgery, doctors soak their hands
in an alcohol bath because the water isn't
free of parasites . Even photocopy
machines are rare commodities.
"They do a lot with so little," Morelli
said. "They squeeze very hard on every
resource."
Because they don't have the equipment we have here, Chinese doctors
rely almost completely on physical
exams rather than lab tests to make
diagnoses. The Chinese are very skilled,
and the UB students learned a great deal
about techniques such as palpating an
a conflict in combining them, Morelli
enlarged liver or spleen .
noted. A patient may receive a Western
Waz had hoped to talk with a Chinese
pharmaceutical preparation while also faculty member who was an expert in
receiving an herbal preparation.
medical ethics . What he found was that
In rural areas, people often seek out the the Chinese haven't developed ethics intraditional practitioner before they see a to an academic discipline as we have. Inphysician
who practices
Western
stead, Waz noted, they use what you
medicine. The traditional methods pro- might call "medical pragmatism."
bably ease the symptoms, and the peoSince the Chinese don't have our
ple seem satisfied with the treatment. Yet lavish resources, they don't have the
the Buffalonians saw people whose thorny ethical issues chat go along with
disease had progressed beyond any them. They don't have co decide whether
medical care, but who might have been a very sick infant should get intensive
helped if they had had surgery earlier. care; they simply don't have any such
"I wonder how many people were care to offer.
ultimately hurt because they kept going
Yet Americans would consider the
to the traditional practitioner, delaying Chinese lavish in hospitalization policies.
treatment that might have been more life Many people who'd be treated as outpa-

AlJfUMN 1988

5

�6

IJ'lat
~cian

I!'

left, a phy sid em onstrat es tradi-

,.

tional Chin ese massage for a pa tient suf-

/.../
,

f ering low back pain
and, at righ t, a wo man
rece ives a cup p ing

I

treatm ent. Note the
marks tha t remain on
th e w om an 's s kin.
A bo ve, bi cy cl es are a
c omm o n for m of
t ran spor tati o n ,
th ough the numb er of
cars is in creasing.

tiencs here are hospitalized in China.
A nd once in the hospital, patients stay
a long time. For instance, a patient who
has a gall bladder removed in the United
States might stay five to seven days; in
China, he'd be in a few weeks, noted
Morelli.

T

he result is that hospitals run out
of beds. Families keep bringing sick
relatives back day after day hoping they'll
be admitted.
The hospitals also run outpatient
clin ics that are very heavily subsc ribed,
More lli noted .
The Buffalo visitors saw some medical
cond itions that aren't common in the
United States, such as rheumatic heart
disease and hepatit is and liver diseases
that aren't alcohol related.
They got to hea r the heart murmurs

AlJTUMN

1988

associated with mitral stenosis . In the
United States, residents might see one
or two classic cases a year, Hea ly said. In
China, they saw six or seven a day.
"Now I can say I really hear the classic
sounds - just the way it's written in the
textbooks. That was a real thrill;' he
observed .
It was hard to get a hand le on just how
common certain diseases are in Ch ina,
Healy said. The Chinese would claim
that a disease was very rare, then show
them 10 cases of it . Healy wasn't sure if
they were trying to gloss over the situation or if there was simply confusion over
use of the word "rare."
Since no one in the Buffalo group
could speak more than a few words of
Chinese , commun ication was a problem .
Medical termino logy, especially drug
names, was hard to translate . Sometimes

they'd just give up on a point, Healy said.

T

he Chinese have a six-day work
week, but also tried to prov ide relaxation for their guests.
"After six days in the hospital, on the
seventh day we toured," Morelli said.
They visited the Great Wall, the Palace
Museum in the Forbidden City, and
Mads Tomb. The imperial sites are very
colorful, almost gaudy, but it was a
welcome contrast to the gray and dingy
city. Since most people burn coal in their
homes, a brown haze hung over the city
on still days, adding to the March gloom.
"It's a hard life in China overall,"
Morell i said . "They do without a considerable amount of day-co-day things we
cake for granted ." T his includes simp le
things like prepared foods or larger things
like the freedom we enjoy.

BUFFALO PHYSICIA N AND BIO MEDICAL SCIENTIST

�7

#1' eijing

physi-

~ cians struggle
to care for the

city's 10 million in­
At left is
the well-baby nursery
at a bus, • district hospital. After the rigors
habitants.

of a six-day

work

week, the Americans
were escorted to popular
tions
Great
and

tourist

attrac-

such as the
Wall, above,
the

Forbidden

City, right.

"It's like they're black and white and
we're color," Morelli said.
But the peole seem happy and hopeful.
A favorite sight of Waz's was the old men
who take their pet birds for a walk to the
park. They'd hang the cages in the trees
while they chatted with their friends.
High rise apartment buildings are
sprouti ng up all over Beijing. Communism is loosening up; a lot of consumerism is starting . People in the street
are selling things and are allowed to keep
the profits. People can voice disagreement with goverment policies, though
not very loudly.
The thing that stands out most in
Schlehr's mind was the time he met a
Chinese army officer who had a copy of
George Orwell's 1984. The novel, a
parable of the evils of communism, was,
in all likelihood, banned in China. For

BUFFALO PHYSICIAN AND BIOMEDICAL SCIENTIST

the officer to even have a copy means
"things are opening up a lot," Schlehr
said .
The Buffalonians were impressed by
the red carpet treatment they received
from the Chinese. Few people in Beijing
own cars, but the Americans were driven
around in a modern Toyota mini-bus,
belonging to the Capital Institute.
Though it was winter, the Chinese tried
to find the best selection of vegetables
for their guests. The Chinese took them
to operas, concerts, and tourist attractions. They had dinner at the fancy Peking Duck Restaurant with heads of all
the city's hospitals.
The group was photographed and
videotaped at every opportunity . The
process always entailed a bit of seatshuffling because each person had to be
seated in a place that reflected his pro-

per status, Morelli explained.
Even parties in Beijing are very structured. There's generally some chatting,
followed by some speeches, then entertainment. Th e Buffalonians decided to
throw a thank-you cocktail party, but the
Chinese guests were very uncomfortable
because they didn't know what to do in
such an unstructured setting, Waz said.
The Americans salvaged the affair by giving some speeches and singing "America
the Beautiful," "Under the Boardwalk,"
and "Take Me Out to the Ball Game:'
The Buffalonians say they want to go
back to Beijing; some in a few years,
some in a few decades. They fully expect
that things will be different, though it's
hard to say in what way.
"So many things cou ld happen," said
Waz. "They have to try to get the best
of our ideas and avoid our problems'.'
AUTUMN

1988

�eets

8

a nu
Bu
hosp
speci
equi
medi
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right
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big l

est

Buffalo and Beijing exchange scholars in new program
By CONNIE OSWALD smFKO

n

tiom
Ul
with
Hig~

~

lectric acupuncture needles combine the old and the new, the
East and the West. They're a symbol of China today .
China is a country coping with
change . le clings co the traditiona l
Chinese medicine used since ancient
times, using techniques such as acupuncture and herbal medicines. Bue after
years of isolation, the most populous
country in the world is eager to adopt
the medical advances of industrialized
nations.
To accomplish that goal, leaders from
the Capital Institute of Medicine of Beijing on June 7 signed a new exchange
agreement with UB's School of Medicine
and Biomedical Sciences and Millard
Fillmore Hospital.
The agreement allows three faculty
members from Beijing to visit Buffalo.
Two will visit for about two months and
the third will visit for a year.
In return, six senior medica l students
from UB, as well as two residents, will
observe medical care in Beijing for one
month.
The exchange is the result of the opening of China to the outside world, said
Du ]inxiang, the acting president of the
Capita l Institute of Medicine of Beijing.
The Chinese wane to learn the advanced technology of the West in order
co develop their own science and
technology.
"In the past, China was isolated, occluded from the world," explained Gao
Tienxiang, professor of cell bio logy and
microbiology at the Capital Institute. "It's

'8'

ALm.JMN 1988

l

i
ll'

~
Q

i
From left: Peter Ostrow, associate dean for curricular and academ ic affairs at VB;
Jan Jennings , pres ident and chief execut ive officer of Millard Fillmore Hospital;
Du Jinxiang; Gao Tienxiang, and John Naughton.

a pressing prob lem we feel."
Gao is also head of the Institute's
laboratory of electron microscopy and
the laboratory of cell biology. He acted
as the translator for the Chinese
dignitaries during their June visit to
Buffalo.
Du and Gao were accompanied by Li
Hui, Gads wife, who is a professor of
microbiology and immunology at the
Capital Instirue and head of the Department of Microbiology at Shandong
Medical University.

that
the
Cap
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oth~
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The exchange agreement is important
because of the increasing ties between
the two countries, said John Naughton,
vice president for clinical affairs and dean
of the School of Medicine and
Biomedical Sciences at UB.
"As we go down the pike, the U.S. and
China are going to have more intense
relationships," Naughton said. "This exchange gives us an opportun ity to be
part of it:'
The Capital Institute was founded in
1960,said Du. Like UB, it's affiliated with

jing
dim
a ne
Mill
Cap
dela

BUFFAW PHYSICIAN ANO BIOMEDICAL SCIENTIST

BUFF/

198i

�number of hospita ls.
But you'll find things in the Beijing
,spirals chat you don't see in Buffalo:
ecialties in tropical disease, pharmacies
uipped to fill prescript ions for
edicinal teas, and departments of
upuncture .
Chinese students enter medical school
:ht after high school and study for five
ars, then work as residents for 5 to 10
ars. The Institute provides physicians
r Beijing, which has 10 million people.
"Health care for 10 million people is a
g burden for us; Du noted .
The Capital Institute also has affilia)nS in Rochester and Texas.
UB already has a systemic agreement
ith the Beijing Municipal System of
igher Education . UB is the only

university in the U.S. to have an agreement with the entire system, which is
somewhat analogous to the City University of New York. O ther U.S. universities
have exchange agreements with only one
co llege in the system.
About 100 students and faculty have
traveled between China and Buffalo over
the past seven years, studying such
dive rse fields as music, education,
engineering, physiology, and h istory.
UB's Health Sciences Library is also
setting up a cooperative relationship with
China's nat ional medical library, which
is part of the C hinese Academy of
Medical Sciences and Peking Union
Med ical College in Beijing.
In anticipation of the new agreement
with the Capital Institute, UB and

Millard Fillmore Hospital sent a delegation to Beijing in March . In the delegation were Daniel Morelli, M.D., vice
chairman of the Department of Family
Medicine at U0 and dirt:ctur of the
residency program at Millard Fillmore
Hospital; William M . Healy, M.D. , who
was then a resident in internal medicine
at Millard Fillmore Hospital, and medical
students Wayne Waz, James M. Schlehr,
Ira Rock, Jerry Igoe, Veronique James,
and Charles Everett.
"This type of exchange buys us more
goodwill than does military aid or other
types of aid; said Morelli. "It would be
a very productive thing for us as a nation to sponsor. It's a way of sharing the
wealth we have in a way that goes
beyond sharing money."

UB mournstwo killed in trafficaccident
By JIM McMUL LEN
~ Chinese professor and a UB staff

'II member were killed June l while

driving home from a dinner party
1at celebrated the schedu led signing of
1e new exchange agreement with the
:apical Institute of Medicine in Beijing.
Killed were Sun Keji, an exchange prossor in anatomical sciences, and Berice Poss, execut ive assistant to the UB
rovost, the driver . Thei r car was struck
roadside by another veh icle on Maple
oad in Amherst .
Three othe r passengers in Poss's car
ere injured. They are Yong-Huan Shen,
:1exchange scholar in mathematics ; Yahen Gu, his wife, and Xijou Hou , a
-aduate exchange student in education,
ho had attended the dinner as an
1terpreter.
The dr iver and a passenger in the
rher car were also inju red.
Sun, 57, had been at UB since August
}87 under an agreement with the Bei:1gMunicipal System of Education . The
inner party anticipated the sign ing of
new three-yea r agreement among UB,
1illard Fillmore Hospital, and the
:apital Institute . That formalization,
elayed because of the accident, took

JFFALO PHYS IC IAN A N D BIO MEDICAL SC IEN TIST

Sun Keji

place Jun e 7.
Born in Sha nghai, Sun received his
degree in medic ine in 1954. He served as
cha irman of the Department
of

Histology and Embryology at the Capital
Institute of Medicine, where he was
recently promoted co full professor.
Sun was considered the best teacher at
the Institute . Here he was also valued as
an excellent teacher, a meticulous researcher and a friend of rhis Universiry,
said Harold Brody, chair of Anatomical
Sciences .
At UB, Sun conducted research on
neuroendocrine control of liver regeneration. His work will be compiled and
published later this year. He also taught
in a medical and dental histology class.
"His teaching in the lab was interesting," Brody said. "He had some difficulty in communicati ng because his
command of English was not so good.
But he was a kind, patient man, excellent
at working one-on-one or with small
groups of students."
He voluntarily tutored several minority
students in histo logy. As one stude nt
said, "You couldn't help but like him."
Sun was scheduled to return to Beijing in mid-August .
A memorial service for Sun was held
June 7. He is survived by a wife and two
children.
AUTU MN 1968

9

�MEDICINE AND THE ARTS
10

Many health-careprofessionalslead double lives. Not only do they work
in the lab and treat the ill, they also write novels, sing, collect art and
build crystal models of nature. Their creativity was the subject of a
June 4 symposium on "Medicine and the Arts," sponsoredby the UB
Health Sciences Library.

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Easing Pain

hat makes a musician? It is "neither nature nor nurture; said Karen Miller Allen, associate health
sciences librarian and former principal clarinetist for
the Mannheim Chamber Orchestra in West Germany. "Boch
must be present before musical and other abilities can emerge."
A UB doctoral candidate in health psychology, Allen lost
the ability to read music after she suffered a head injury . She
has long been interested in the psychological and physical
aspects of music.
"Twenty years ago it was possible only to speculate why
music such as Bach's Massin B Minor makes most people feel
a certain way. Now it is known that specific chemical changes
are taking place, such as the production of endorphins and
enkephalins.
"Music's role in psychoneuroimmunology is just beginning to be explored, and it is being found that music can influence important changes in this area, too. In Germany, music
often is used during anesthesia and during the post-operative
period . It has been found that, especially when the patients
pre-select their own music and hear it through headphones,
that they require less medication, and report reduced pain
levels."

Alll1JMN 1988

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W. Somerset Maugham
mong the world's physician writers, few are as well
known as W Somerset Maugham, whose writing reflects the "tremendous bitterness and pain in his life,"
said John Gaeta, chief of pathology at Roswell Park Memorial
Institute and professor of pathology in the medical school.
Throughout his life, Maugham was a man of sear ing ambivalence. Born in France of British parents, he was orphaned at IO,taken to England where he was raised by an
uncle, and educated at King's School, Canterbury.
As a youngster, Maugham stammered and endured the
pain of being mocked by other children, said Gaeta. In fact,
stammering was to be a lifelong affliction, so severe that the
author avoided the telephone entirely, Gaeta said.
In Heidelberg, Maugham learned German and acquired
a "tremendous philosophical background ."He decided to study
medicine and graduated from Sr . Thomas' Hospital medical
school in London. His experiences as a young intern in
obstetrics are reflected in his first novel, Lizaof Lambeth(1897),
the modest success of which prompted him to abandon
medicine. The author of novels, short stories and plays,
Maugham is perh aps best known for his semi-autobiographical
novel Of Human Bondage (1915),the story of a medical stu-

BUFFALOPHYSICIANAND BIOMEDICALSCIENTIST

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BUFFAU

�r's painful maturation.
Another famous physician writer, Gaeta said, was Sir Arr Conan Doyle, who created the personality of the ideal
!Ctive in Sherlock Holmes. "The literature is full of detecs but none has had the popularity of Sherlock; said Gaeta .
Yet Doyle created an interested counterweight to this
re of Holmes, who is so smart that his humanity is ques1able, Gaeta noted . "Watson was created for balance.
:ice that he's a doctor. He would bring Holmes down to
:h. The personality of Sherlock Holmes is not so import as the balance between the two men:'
Anoth er writer who infused his writing with observations
ned from medicine was the Scottish physician A. J. Cronin
&gt;6-1981),who was educated at the University of Glasgow
I served as a surgeon in the Royal Navy during World War
:-leis an example of tenacity and optimism; said Gaeta.
medical inspector of mines, Cronin studied occupational
:asesin the coal industry. One of his many popular novels,
· ScarsLook Doum, was set in the Welsh coal mining region.
Cronin began a London practice in 1926 but quit shorthereafter because of ill healch . He then used his free time
vrite his first novel, Hatter'sCastle (1931), which was made
&gt; a film, as were five other Cronin novels. Adventures in
&gt; Worlds is an account of his years in medicine.
As a young man about to begin medical training, William
fos Williams showed his poetry to an MIT professor he
:w. "Stick to medicine; the professor told him. "Your imions of Keats are very good but you'll need co earn a living~
Williams did stick to medicine, and spent a lifetime in
&gt;untry doctor's practice. He also stuck to writing, turning
a lifetime of work that would earn him the title of "the
st influential American poet of the 20th century."
Williams was the subject of the keynote address delivered
(athryn Montgomery Hunter . Hunter is associate professor
1 director of the Division of Medical Humanities at the
iversity of Rochester School of Medicine and Dentistry.
A prolific writer of prose in addition to poetry, Williams
: born in 1883 in Rutherford, N.J., and lived there until
death in 1963. Later that year, he was posthumously awardthe Pulitzer Prize in poetry for his Picturesfrom Brueghel,
' Ocher Poems(1962). His poetry, which often concerned
most ordinary of subjects, benefited from his medical prac·, Hunter said.
"Throughout his life, Williams maintained that his
:lical practice sustained his poetry and that his poetry sus1ed his daily practice of medicine," she said . "He always
med he became a doctor in order to write."
In his autobiography, published in 1967 by New Direc1s, Williams wrote:
"As l say, often after I have gone into my office harassed
:&gt;ersonalperplexities of whatever sort, fatigued physically
1 mentally, after two hours of intense application to the
:k, I came out at the finish completely rested (and I mean
ed) ready to smile and to laugh as if the day were just start. That is why as a writer I have never felt that medicine
:rfered with me but rather that it was my very food and
1k, the very thing which made it possible for me to write."

'ALO PHYSIC IAN AND BIO MEDICAL SCIENTIST

Daily, close observation of the mundane and of the
rhythms of ordinary American speech often provided the poet
with the subject s and themes of his works, as well as the
sounds transferred to the dialogue of his characters.
And somehow Williams found time to gee it all down on 11
paper. That could mean jotting down poems on prescription
pads (some of which are among the 20,000 pieces of Williams'
writing stored in UB's Poetry/ Rare books collection). By keeping a sheet of paper rolled into his typewriter at all times, he
could even snatch a few minutes of writing in between patient visits.
Many important moments of his practice are captured in
poems such as "Complaint" and 'The Last Words of My
English Grandmother~
Bur it is Williams' first-person doctor stories, including
the memorable "Use of Force; that were the most "medical"
of his works, according to Hunter. These short stories, written in the '30s and recently collected in paperback, are often
told from the point of view of"a crusty, curmudgeony pediatrician."

Music Th erapy

usic is an extremely personal yet totally universal experience;' said Jill Scott, a nurse who uses
her voice and guitar to soothe the pain of the
elderly and terminally ill. Interspersing her talk with performances, Scott said "music is a powerful tool char can leave
one defenseless. One must respect a person's right to choose
the type and amount of music, or even not to hear any music
at all.
"Some clients respond superficially, some emotionally; said
Scott, on-site coordinator of the RN Satellite Program at
Fredonia State College . For some it is an intellectual experience, in which the composer's style and technique are
topics for discussion. For ochers, it is a physical sensation in
which they beat time or move their bodies co the music.
The music therapist, she says, "needs to trust music to
perform the healing. When music is chosen carefully, words
can become totally unnecessary~ In using music therapeutically, Scott first tries to "convey a sense of trust." She then attempts to help the patient express his or her needs and desires.
Sometimes, of course, the music is just for fun .
Lastly, Scott tries to help her clients find "self-fulfillment
and some relief, to help them take care of unfinished business
before they die."

AUTU MN 1988

�... .., ..
.

12

.... ~·,\"t

:,

cian. Ac Union College, he was a disc jockey, program director and general manager at the campus radio station. At one
time, he even considered a broadcasting career .

.·.::•-/:\:
-: ·

i, ·,

Singing

aritone Brian Zunner, D.D.S., the recipient of a B.F.A.
degree from UB, performed four songs by Brahms,
accompanied by James M. Bigham. Zunner, who has
been a soloist with the Buffalo Philharmonic, is in the Dental Residency Program at the Veterans Administration Medical
Center of Buffalo.
UB assistant professor of clinical pediatrics and
otolaryngology Joel Bernstein presented a short recital of
diverse works including three lieder by Schubert, arias by
Mozart and Offenbach, and a Rodgers and Hammerstein
song. He was accompanied by pianist Marjorie Lord.
Bernstein is a lecturer and consultant to the Music
Department. He has studied vocal performance for the last
fifteen years and has performed throughout Western
New York.

Jan
ichard (Dick) Judelsohn finds fulfillment in both jazz
and the healing arts. The Buffalo pediatrician, who has
hosted a jazz program on WBFO since 1976, seeks to
educate the public on jazz from 1945-1965, the focus of his
show. Whenever possible, he tries to include commentary
about the artists, sidemen, and arrangers, in addition co the
date of the recording. In shore, he looks for clues that will
give his listeners "optimal enjoyment."
Judelsohn, a 1967 graduate of the Medical School and
associate UB professor of pediatrics, collects his knowledge
through listening to jazz radio programs, talking co musicians,
going to clubs and his own playing of the saxophone. Jazz
has been his passionate interest since high school when he
became interested in the art form as both a fan and a musi-

Atm.J MN 1988

Herbert A. Hauptman

(p/ q) (q/ p)

=

(left)

(-1)1 /2 (p-l)xl/Z(q-1)

he Law of Quadratic Reciprocity, a formula from
number theory, is "the supreme example of the art of
mathematics," according to Herbert A. Hauptman, UB
professor of biophysical sciences.
"Youcan see this beautiful formula has a great deal of symmetry just by looking at it. It is well-worth spending the two
to three weeks it would cake to prove its validity:'
Mathematics is an art, not a science, said Hauptman, who
is also president and research director of the Medical Foundation of Buffalo and a recipient of the Nobel Prize in
Chemistry.
"The great 20th century philosopher and mathematician
Bertrand Russell wrote: 'Mathematics possesses not only truth
but supreme beauty, a beauty cold and austere, like chat of
sculpture, sublimely pure and capable of a stern perfection,
such as only the greatest art can show: "
Unlike any ocher art, however, mathematics appeals not
to the senses but to the intellect, Hauptman pointed out. le
is also a more demanding art.
"It requires nothing less from the viewer but chat he participate in the creative process itself because the act of
understanding requires this participation. The demands on
the viewer are great but the satisfactions and the pleasures
are correspondingly great."
Certain patterns found in the visual, literary, and musical
arts, Hauptman said, which "almost always have a regular or
repeating motif and show varying degrees of symmetry," are
analogous to "the patterns of logical inference, the very essence
of mathematics.
"It is the recognition and appreciation of these patterns
and these symmetries, as well as their significance, which gives
pleasure when viewing a work of arc, listening co a musical
composition or reading a poetic one, or comprehending usually after a great deal of effort - a mathematical exposition."
Hauptman pointed to geometry as a more readily accessible area, combining the intellectual features of mathematics

BUFFAlD PHYSIC IAN AND BIO MEDICAL SCIENTIST

�and the visual appeal of art.
"For many years I've been intrigued by the construction
of these extremely beautiful, fascinating geometric solids; he
said. "I first made them out of cardboard, then I learned co
work with stained glass - using the colors to enhance the
symmetry and beauty of the geometric forms.
"Was it then only coincidence that my life's work as a
scientist was concerned with crystals and their structures
which often mimic their geometric counterparts in the world
of mathematics?"
Transparent models of crystal s created in rose and blue,
pale green and white, were projected in slides during Haupt·
man's speech. Several were also on display at the Health
Sciences Library.

13

Art Collec ting

ow does one build an art collection? In the case of
Donald A. Lar son, UB's associate vice president for
clinical affairs, it came after years of study, observation,
and family consultation. Larson said his collection is varied
in terms of media, artists, styles and origins. It runs the gamut
from comfortably decorative works to tension-producing
abstracts .
In the view of Larson and his wife, Mimi, art serves to
differentiate

Ph ysician Wr iter

o all those physicians leading double lives as artists, what
does the artistic impu lse cost?
It doesn't matter, according to Martin E. Plaut,
novelist and UB professor of medicine .
"le is still better to try than not to try; he said. "Many
people who have somehow suppressed the artistic impulse
have a feeling of loss, of what might have been. To me, the
cost of not trying is greater."
Plaut knows of what he speaks. He has published four
novels, several under the pseudonym Paul Marttin (a scrambling of the letters of his name), including Cocoa Bll1fles,
called
"a stunning novel of love, sex, corruption ." He is also the
author of The Doctor's Guide to You and Your Colon: A Candid, Helpful Guide to our #1 Hidden Healch Complaint. But he's
known failure, too.
"I sent off stories in manila envelopes for years; he said.
"Editors handled submissions like they were samples of stool.
"But there are those little epiphanies, coo; Plaut added.
"Like when you walk into a library and find your book listed
in the card cata logue."
The artistic impulse is not limited co the printed word,
Plaut emphasized - or co any of the so-called arts for that
matter.
"It may be an attempt to grow roses, or to describe a sunset
after four days of clouds . Even if it's the way you tell stories
or sing in the shower - if you possess it and ignore it, it will
cost you more."

BUFFALO PHYSICIAN AND BIOMEDICAL SCIENTIST

the spac e within their home. Accordingly,

said

Larson, "the collection should be controlled in its hanging
to provide that differentiation which supports our various
needs . Without this selectivity, there would be discordancy
both for ourselves and our guests."
From the beginning, the Larsons wanted theirs to be a
teaching collection for their children . The Larson children
would often return to college with a piece of art, bring it back
a year later and take another painting or drawing .
As a result, Larson joked, "we have a satellite collection
in New York City, Austin and Chicago ." Occasionally, the
Larsons' taste diverged, but they were able to find common
ground nonetheless. "We have learned things about ourselves."

Pho tos by Nus baum

xhibitors in the Medicine and the Arts symposium were:
lvan L. Bunnell, UB clinical professor of medicine and
watercolor artist; Karen Flynn-Miller, dentist and mixedmedia artist; Herbert A. Hauptman, UB professor of biophysical sciences and glass sculptor; Anthony Keller, nurse
and harpsichord builder; Sanford L. Nusbaum, UB clinical
assistant professor of oral surgery and photographer; David
]. Triggle,dean of the UB Pharmacy School and photographer,
and Peter L. Weinmann, UB clinical assistant professor of dermatology and photographer . •

AUTUMN 1988

�14

TYKE TRIK E
Patent,pending device makes paraplegic one of the gang

AlITTJMN 1988

BUFFALOPHYSICIANAND BIOMEDICALSCIENTIST

�..

he colorful tricycle chat
perky six-year-old Sarah
Tangelder rides around
her suburban Clarence
neighborhood
looks
similar co ocher "Big
Wheels" popular with kids her age.
But the dark-haired youngster in the
purple sweatsuit quickly explains that
her bike is different,
special,
one-of-a-kind .
Equipped with a device based on a
patent-pending concept developed at
UB, the tricycle provides her with
mobility while simultaneously delivering
physical therapy for her legs, paralyzed
by transverse myelitis.
As she pedals around her driveway, she
gets one hour of electrical stimulation to
her leg muscles each day without having to set aside extra time for her therapy.
Until the UB team, led by Frank
Mendel, Ph.D., and physical therapist
Dale Fish, Ph.D., designed the concept
for Sarah, her mobility was limited to a
wheelchair.
"We felt it would be ideal if she could
have therapy as she played; says Mendel,
an associate professor of anaromica l
sciences in the School of Medicine and
Biomedical Sciences . lc's hoped che
therapy will strengthen her muscles and
cardiovascular system.
Aided by health sciences instrument
shop director William Tanski, Jr., and
retired engineer Robert Kell, the team
studied and modified a child's big-wheel
tricycle .
Handlebars were replaced by hand
cranks, which are connected by chains
ro the foot cranks, allowing Sarah co use
her arms to propel the tricycle. Cams
mounted on the common axle linking
hand and foot cranks activate microswitches that in turn activate a pair of
battery-powered
po rtable electrica l
stimulators which send electrical signals
co selected muscles.
Because the speed at which she turns
the hand cranks controls the pedals and
stimulation co her legs, she can increase
or decrease the speed at which she
trave ls, but her leg muscles will always
be stimulated at the correct arcs of
movement.
Use of electrical stimulation for
therapy is nor new. It's often recommend-

BUFFALOPHYSICIAN AND BIOMEDI
CAL SCIENTIST

ed for individuals who, because of illness
or injury, cannot independently exercise
weakened or paralyzed muscles. As
carefully controlled current flows from a
stimulator via electrodes caped co skin,
underlying muscle is activated.
Although this is an effective form of
therapy, it is often inconvenient for a patient to travel several times weekly to a
hospital or rehabilitation center where
such therapy is typically administered.
Even if portable models are used at
home, the individual usually reclines or
sits during therapy.

"The design can also help prevent
pressure sores, which develop in chose
who sit or lie in a single position for long
periods of time," says Mendel. The sores,
often referred co as "bedsores; occur IS
when lack of body movement cues off
blood supply and nourishment co areas
of the skin.
Sarah's parents, Jim and Melanie
Tangelder, report that her neurologist,
James Teter, M.D., has detected improvement in muscle strength and increased
sensibility since the child began using
her special Big Wheel this winter .
When it's coo cold to ride outdoors,
Sarah switches the tricycle ro a stationary mode, which allows her to ride
in place while her muscles receive their
alternating JO-revolution stimulation
and JO-revolution rest cycles for an hour
daily.
The stimulation-rest cycles and selection of muscles co be stimu lated can be
tailored to the individual's needs . As
Sarah
gains muscle endurance, the
Sarah Tange lder and Frank Mende l, Ph.D.
stimulation cycle will be increased .
"Being able to connect the portable
While Sarah uses her purp le padded
stimulator to a mobile vehicle, which the wheelchair to get about much of the
paraplegic individual can incorporate in- time, she's able to stand with the aid of
to normal activity, encourages consistent
specia l, sturdy braces.
therapy; says Fish.
The UB team estimates that the cost
Because the Big Wheel is inappropriate to equip the Big Wheel, excluding labor,
for older children and adults, the UB ranges from $1,200 to $1,500. The major
team is working on application of their expenditure is for the portab le electrical
design to wheelchairs .
stimulacors priced from $500 to $800
"The hand cranks could be incor- each.
porated near the area of the brake
Fish and Mendel be lieve the patenthand les typically found on the pending concept might also benefit
wheelchair; Mendel explains. The chair's others whose legs have become paraconventional footrest could be replaced lyzed or severely weakened by certain inwith pedals, which would be connected juries or one of a hose of neuromuscular
co the handcranks
and electrical
disorders .
stimulators much as they are on the Big
As long as the nerves from the spinal
cord co the muscle are intact and the
Wheel.
Fish notes the team is particularly en- muscles are healthy, electrical stimulation
thusiastic about chis work because could be beneficia l. People with multiwheelchairs are the primary mode of ple sclerosis, stroke, or other neurologiclocomotion for many paralyzed people. ally induced paralyses may be candidates
Thus, a wide variety of individuals could for this kind of program, they say.
receive electrical stimulation while
The team hopes there will be a way to
engaged in their everyday activities .
produce the design for manufacture so
For the very young, an all-metal tri- it's easily available in the future for others
cycle fitted with the UB design might be like Sarah.
sturdier than the all-plastic Big Wheel.
The concept was presented in a scienAs Sarah rides with sister Grace, 5, and tific session at the American Physical
nine-year-old brother Tom, she's also ex- Therapy Association meeting in Las
Vegas on June 14.
ercising her cardiovascular system.

AUTUMN 1988

�ONE
STEP
FURTHER
16

Electricalstimulationtechnology
movesfrom rehabilitationsetting
into the realmof everydaylife
By MARY BETH SPINA

computer specialist whose
lower right leg was
partially paralyzed
as the result of a
spinal inju ry 32
years ago is now
able to walk more
normally because
of the efforts of a
research team at UB.
The team has adapted existing electrical stimu lation technology, bringing it
from the rehab setting to everyday life,
to benefit UB staffer Jay Leavitt. (The
same team has enabled a para lyzed sixyear-old to ride a tricycle - see accompanying story .)
Despite his spina l cord injury, which
resulted from a freak tumbling accident
in college, Leavitt has maintained an active lifestylebut was somewhat hampered
by an inability to lift his right foot from
floor surfaces as he walked.
"Every 12 days, I had to have the sole
of my right shoe replaced - sometimes
more often if I walked a· great deal on
rough surfaces," he relates.
In addition to the cost of shoe repair,
Leavitt, who trave ls a great deal in his
work, grew impatient with the amount
of time it required for him to cross a
parking lot or a large carpeted area. UB
anatomist Frank Mendel, Ph.D., and
physical therapist Dale Fish, Ph.D.,
worked with Leavitt to reduce his

AlJTUMN 1988

decades-old
pro blem by electr ically
stimulating various
muscles in his partial ly para lyzed
limb.
"We reasoned
that if stimulation
could be activated
by a heelswitch in
his shoe that could cause his affected foot
to clear the floor, he could walk more
normally," said Fish.
"And ... save a lot of shoe leather in
the bargain," added Mende l.
A lthough portable battery-powered
electrical stimulators are availab le, they
are typically used in clinics as individuals
sit or recline during therapy.
The team, which includes retired
engineer Robert Kell and Leavitt himself,
decided to modify a commercial functional electrical stimulation system (FES)
called Respond II equipped with a
heelswitch to activate stimulation duri ng
the "swing phase" of gait wh ich occurs
when the heel is not in contact with the
floor.
The heelswitch is connected to the
electrical stimulator which is in tum connected to surface electrodes applied over
leg muscles and the top of the foot. Electrical pulses cause the muscles to contract
and help lift Leavitt's foot and leg during the "swing phase ."
An associated goal is to improve con -

BUFFALO PHYSICIAN AND BIO MEDICALSCIENTIST

�venience and durability of the system,
says Mendel. Ordinary
modular
telephone cables, equipped with standard snap cpnnectors, connect the
stimulator to the electrodes. The cables 17
and connectors allow fast connection
and disconnection to facilitate dressing
and toileting.
The cable system worn under Leavitt's
trousers connects to the stimulator and
eight AA nickel cadmium rechargeable
batteries which are compactly stored in
an ordinary camera shoulder case. This
arrangement is more convenient than
wearing the stimulator on the belt
because it does not bind while sitting or
block access to pockets.
The team concedes there are still some
"bugs" to be worked out with the
durability of the heelswitch, which must
be replaced every two months .
Although the basic techno logy for th is
system is readily available and used in
clinics, few individuals use such systems
on an everyday basis.
"Companies which developed the FES
did not have a person like Jay Leavitt in
mind - an active person who will subject existing units to heavy-duty use day
after day," says Mendel.

The

UB team notes that Leavitt is able
to walk more normally without lurching
and without his mechanical leg brace.
Further, the stimulated muscles are
becoming stronger and therefore will
continue to improve his gait over time.
Although his physician, James Teter,
M.D., notes improvement in gait and
muscle strength in the affected leg as a
result of using the stimulator, Leavitt will
continue to need the device in the future.
Leavitt, who with his wife, Ginger,
raises Morgan horses on a farm in Elma,
outside of Buffalo, finds the use of electrical stimulation to be a tremendous
improvement.
"Before I began using the device; says
Leavitt, "I was burdened with a heavy
brace, and my foot wouldn't clear the
ground . Walking was time- and energyconsuming."
~
This research was also presented by the
l!I
~ UB team during the scientific sessions of
~ the American Physical Therapy Associa~ tion meeting in June.

!

AUTU MN !988

�18

''

yclosporine
isn't the end of the
(transp lantation) story. The crusade goes
on; according to Thomas E. Starzl,
M.D., who is known for his work in
human organ transplantation .
Starzl addressed approximately 250 immunologists and scientists at the 11th International Convocation on Immunology on June 15, sponsored by the Ernest
Witebsky Center for Immunology at UB.
Delivering the Ernest Witebsky
Memorial Lecture at the event, Starzl

AUTUMN 1988

said that a new drug, FK 506, cou ld
be an improved medication for maintaining the fine line of avoiding donor rejection of the organ without appreciable
toxic side effects.
Both cyclosporine, which is now given
to organ recipients, and FK 506,
discovered only a few years ago in Japan,
are immunosuppressants . Cyclosporine,
however, has severe side effects leading
to kidney damage.
But, Starzl said, cyclosporine and FK
506, used together, promise to be a
significantly improved combination for
treating patients who have undergone
human organ transplants. FK 506 has
not shown toxicity in most animal
studies, including non-human primates.
Starzl, a professor of surgery at the
University of Pittsburgh, noted that one
interesting thing about modem drugs is
that interrelations with other drugs can
be analyzed much faster because of
modern techno logy. Thus a major breakthrough in the technique of assessing
immunosuppressive potent ial of drugs
was the development, by Starzl's collaborators, of a standardized system of
employing cell cultures . Using this
system, all information now available on
FK 506 with cyclosporine A was acquired within six to eight weeks.
Within the first year that liver
transplant
patients
were given
cyclosporine
in combination
with
steroids, the survival rate doubled and
then tripled. There were never any steps
backward, said Starzl.
"I th ink cyclosporine and FK 506 will
be soul-mate drugs because of their
synergism (the interaction of the drugs
produces an improved effect over those
found in each drug separately); he said .
"The 64 dollar question is, is FK 506
toxic in humans?" Starzl said .
According to Starzl, in rats and baboons it isn't, which leads scientists to
believe it won't be toxic in humans .
In vitro experiments strongly suggest
that FK 506 in combination with
cyclosporine A will allow use of both
drugs in such low doses that toxicity is
extremely unlikely .
lmmunosuppression is the part of
transplantation that gives this specialty
a kind of peculiar identity all its own, ac-

ORGAN
TRA

New drug, FK 5(
for avoidin

''I

think c

and FK 50c

because oft

synergism,''1
explained. I

64 dollar qi

is, is FK SC

toxic in hun

BUFFALOPHYSICIAN AN[

�cording to Starzl . There are two other
areas essential for successful transplantation. One is tissue preservation and the
other is tissue matching.
Improved tissue preservation techniques have made it possible to preserve
organs longer so that a possible matching
recipient can be found, and the donor
organ can be transported to the recipient.
In 1959 scientists described an organ
profusion technique (putting fluids
through the organ) by which organs
could be preserved for several hours . This
process has been continually improved.
Donor livers could survive for up to 10
hours in 1976, bur using a new profusion
solution described in 1987, donor livers
now can survive for 24 to 30 hours,
allowing transportation between Europe,
the U.S., Canada, and South America ,
as well as between South East Asia and
Australia and New Zealand.
"The whole conduct of liver transplantation was revolutionized because of this
preservation process; said Starzl.
"Although this is a truly revolutionary
development in liver transplantation; he
added, "it's not the end of the line
because greed is everywhere . I mean
greed in a nice way, beca use no one is
ever satisfied. It should not be long
before donor livers will surv ive for a
week or more.'.'
The th ird essential aspect of transp lantation is tissue matching . However, convent ional matching has gone to the back
burne r with improved and powerful immunos uppressants, such as cyclosporine
A.
A cross-matched test in which the
seru m of t he prospective recipient is
tested with the donor's cells before
transplantation is important in preventing a certain number of very early
rejections.
Starzl pointed out that Felix Milgrom,
disti nguished professor of microbio logy
at UB, contr ibuted significantly to identifying antibodies in the recipient as the
cause for h yperacute rejection; this is rejection of the organ within a matter of
minutes after grafting.
Cyclosporine and FK 506, no matter
how effective in cell-mediated rejection,
cannot prevent hyperacute syndromes .
There cross-matching seems essential.

~$PLANT
ATION
506, shows promise
ing rejection

~

1---1

---- "'fi

-----.!

....;i
~

..,

cyclosporine
06 will be

drugs
their

question

,06
imans?''

/\ND BIOMEDICAL SCIENTIST

T

he final major po int Starzl made
was that there is new hope that
intestinal transplants will be a
19
reality some day.
Prospects for intestinal transplantation
include patients with sho rt bowel syndrome, in which uptake of nutrients is
severely impaired or impossible because
of lack of intestinal mucosa! surface (lining of intestines) .
Altho ugh there have been no completely successful intestinal transplantations, Starz l and his team are working
diligently to find out what the problems
are and how to solve them .
Last November Starzl transp lanted
small intestines into a two-and -a-halfyear-old girl.
The donor intestines, because of the
large number of immu nologically reactive cells present in its tissues, were
pretreated with monoclonal antibodies
to T-cells. The transplant was accepted
and was functioning.
Then, about three months after the
transplant, the child became sick and
doctors discovered lesions in her liver.
Upon biopsy, they found extended lymphomas, usually associated with the
Epstein-Barr virus, a member of the
herpes virus family.
"We have no idea why the little girl
developed the lymphomas in her liver or
if it had any connection
to the
transp lant, but we intend to find our;
said Starz l
It was of interest that the cells of the
lymphoma were of recipient origin . It
could be that reactivity of donor lymphocytes to recipient cells facilitate
development of lymphomas .
T his child was the first one who lived
over six months and had a fully functional intest ina l transplant.
"Everyone loved this child and was
very sad when she died; expressed Starzl.
"Bur I feel at least an attempt was made.'.'
What is the difference between the
bus iness of medicine and the crusade,
asked Sta rzl. Th e business of medicine
is what successful transp lantation seemingly always becomes, he answered, and
the crusade is what hasn't yet been
achieved . Intestinal transplantat ion is
currently one of the transplant surgeon's
majo r crusades .

AUTUMN 1988

�20

to have an allergic reaction to gluten and
muse restrict it in their diets, they do not
form the damaging antibodies which differentiates it from gluten sensitive
enteropathy (celiac disease); Kumar
explains.
There may be many undiagnosed cases
among adults who've never shown
clinical symptoms of the disorder.
"By using our test as a simple screening device, we may find celiac disease is
more prevalent than previously believed;
.,. __
""'1 z Kumar adds . The test may also be used
., __ .. ~ to monitor effectiveness of dietary treac'----l j ment for diagnosed celiac patients.
§ Or. T P. Chorzelski of the Warsaw
~ Academy of Medicine in Poland and his
lllliiiiiiiill
.. ___
.,~ ~ colleagues initially identified the antibody which is triggered by gluten
figures on incidence in the U.S. popula- intolerance.
tion . Studies by others suggest it is more
A long-time collaborator of Kumar
prevalent among certain Israeli popula- and Ernest Beumer, Ph.D., of UB,
tions and may be found in one of every Chorzelski found chat the antibody ap300 persons in Ireland .
peared in the blood of 70 per cent of
To confirm diagnosis, a biopsy is now those diagnosed
with dermatitis
taken of the mucosa lining the small herpetiformis, a rare skin condition
bowel with another biopsy taken six associated with chis specific intolerance .
months after the individual is placed on
"Ou r research together on skin
a gluten-free diet. Additional biopsies disorders with immune system commay be required.
ponents led us to investigate the possibiliThe new test, on the other hand, uses ty the antibody would be detected in
a small amount of drawn blood . Not on- blood of those with celiac disease as well,"
ly is it less painful than a biopsy, it is in- Kumar explains.
expensive and less time-consuming.
Blinded studies conducted in conjunc"With conventional biopsy techniques, tion with Buffalo Chi ldren's Hospita l
alternated with dietary challenges of giv- showed the new test revealed the aning the patient gluten products, diagnosis tibodies in the b lood of two previously
may take 18 months compared co a day diagnosed celiac patients in a group of
or so using our blood test; Kumar 100 persons . Subsequent blood tests on
explains .
ocher groups with unfailing accuracy
Treatment of celiac disease consists of identified diagnosed celiac patients in
putting the patient on a gluten-free diet group studies which included patients
which eliminates the offending protein . with a variety of other disorders.
Those who do not have the autoimmune
Also involved in the ongoing studies
disorder, which appears co run in as well as refinements in the test are
scientists at the School of Medi cine in
families, do not make these antibodies.
"While some people have been shown Haifa, Israel.

TESTDEVELOPED
FORCELIAC
DISEASE
By MARY BETH SPINA

A

safe, accurate, inexpensive blood
test to diagnose celiac disease has
been developed by a team of UB
researchers in collaboration with colleagues in Poland and Israel.
Find ings of studies conducted on the
new test were presented by Vijay Kumar,
Ph.D ., of UB's Departments
of
Microbiology and Dermatology, at the
11th International Convocation on Immunology June 16. The convocation was
sponsored by the Ernest Witebsky
Center for Immuno logy at UB.
The test, which has been developed
over the past three years, has been shown
to be 100 per cent accurate and promises
to replace intestinal biopsies (surgical procedures) now used to diagnose the
disorder .
Kumar says the immunofluorescence
test is now being adapted so it can be
marketed in convenient test kits in the
future . The test is now available at a cost
of $40 through UB and a few other
medical centers. Test results are generally available within 24 hours, he said.
Celiac disease, characterized by weight
loss and diarrhea, causes changes in the
small intestine due to a reaction to certain proteins called glutens found in
wheat and other types of grain. 1n
medical terms, the disease is known as
a gluten sensitive enteropathy .
The test detects antibodies formed in
the small incesti!"}ein reaction to the
gluten protein. The antibodies appear as
cell-tale markers only in blood of celiac
patients and those with a rare skin
disease called dermatitis herpetiformis.
Primarily a disorder found in infants
and young children, celiac disease is considered rare, but there are no accurate

AlTl1JMN 1988

BUFFALO PHYSICIAN AND BIOMEDICAL SCIENTIST

i

�21

small general hospitals in rural
communities. Or. Nelson is now
living at 2734 Miradero Or. in
Santa Barbara, Calif. 93105.

Steven G. C line (M' 4 7) • of
Atlanta, Ga., has retired after
serving as chief of radiology at
South Fulton Hospital for 25
years.

M. Luther Musselman (M'3 7)

John C. Inman (M'33) • writes,
"I would enjoy news from
classmates." Or. Inman retired in
1971due to a coronary. His winter
address is 18 Palm Drive, Lake
Worth, Fla. 33461.

M. Luther Musselman (M'37)

i

• is president of the Medical
Society of the County of Erie for
a one-year term . He is also the
president of the Buffalo Academy
of Medicine. Dr. Musselman is
director of medica l education at
Millard Fillmore Hospital and an
associate professor of Medicine at
UB.

Carl

J.

lmp e llitt er (M'46) •

writes, "Following a 27-year
thoracic surgical practice in
Scottsdale, Ariz ., l have been invited to join the Mayo Clinic,
Scottsdale, Department of Ca rdiovascular Thoracic Surgery."

Linc o ln D . Ne lson (M'46) •
has retired after serving 35 years
as a medical missionary in the
Philippines, where he was directly involved in establishing th ree

Raphael S. Goo d (M'48) • was
recently elected vice president of
the South Florida Psychiatric
Society. Or. Good is professor of
psychiatry and obstetrics and
gynecology at the University of
Miami School of Medicine.

Yale So lomon (M'50) • a New
York ophthalmologist, periodically takes time off from his busy
practice
and his work at
Southside Hospital, where he's
chief of ophtha lmology, and his
teaching at the State University
of New York at Stony Brook
Medical School, to go to India,
Thailand, and the Caribbean,
where, paying his own way and
operating gratis, he has restored
sight to hundreds of indigent people. Or. Solomon is the founder
of a tax-exempt organization,
Volunteer Eye Surgeons International (VESl) - with the express
purpose of raising funds to cover
the costs of travel and living expenses for eye surgeons on onemonth assignments to needy
areas of the world. "VESl is
unique among the large number
of groups involved in providing
eye care in developing countries
in that it's the only one to cover
volunteer expenses." For further
information about Volunteer Eye
Surgeons International, contact
VESI, 375 East Main Street,
Bayshore, New York 11706.

BUFFALOPHYSICIAN AND BIOMEDICALSCIENTIST

Stephen C. Scheiber (M'64)

And rew Norr is (M'82)

Myra R. Zinke (M'SO) • writes,
"I am home on disability because

professor of medicine in the
University of Texas, San Antonio
Family Practice Department.

of cancer and would love to hear
from friends and colleagues." Dr.
Zinke resides at 4401 Roland Ave.,
Baltimore, Md . 21210.

Andrew Nor ris (M'82) • of

Stephen C. Scheibe r (M'64) •
professor of clinical psychiatry at
Northwestern Medical School, is
president-elect of the Association
of Academic Psychiatry . Or.
Scheiber is also chairman of the
APA Committee on the Impaired
Physician, co-chairman of the
Fellowship Committee of the 11linois Psychiatric Society, and has
been elected a member of the
Committee on the Study of
Evaluation Procedures of the
American Board of Medical
Specialties .

Fort Co llins, Colo., has published "Cyclotorsional Oiplopia
Following Retinal Detachment
Su rgery" in the journal Pediatric

Ophthalmologyand Sirabismus.
Jos eph Ke ith Miller (M'83) •
writes, "I have completed a
fellowship in EEG and epilepsy at
the Un iversity of Illinois at
Ch icago. I will be joining the
Johnson Neurological Clinic in
High Point, N.C. in June."

Joseph P. Ri enzi (M'85) •
writes that after three years of a
genera l diagnostic radiology
residency, he began a fellowship
in nuclear radiology on July I at
Yale-New Haven Hospital, Yale
Univers ity School of Medicine.

Kenneth Lee Gayles (M'73) •

M ichael S. Mill er (M'86) •

has been elected to fellowship in
the American College of Cardiology. Or. Gayles is an assistant
professor of medicine at UB.

writes that he is a psychiatry resident at the Medical College of
Virg in ia H ospitals . His wife
Pamela has just received her
master's degree in mental health
nursing from the Medical College
of Virgin ia.

Tone Johnson, Jr.(M'75) • has
been appointed clinica l assistant

AUTUMN 1988

�22

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fessio1
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vance
years:
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AlJl1JMN 19&amp;

BUFFALOPHYSICIANANO BIOMEDICALSCIENTIST

BUFFAL

�23

IBSIDENTS
SUPPORT
LIFE
&gt; Gettinghands-ontrainingin advanced cardiac life supportwasone of the best
r

1rtsof a new orientationprogram,say UB residents i ~ UB placeditself one step
1ead of State regulation
s by requiringthe trainingof all of its residents. ~ ·~
r

r

a common myth that all doctors know

'R, noted Glenda Donoghue, M.D., direcof continuing medical education and pro;ional development at UB.
~he UB School of Medicine and
,medical Sciences gives training in basic life
)port skills, but not all medical schools do.
It's our perception, and the State's, that
idents should know not only basic, but ad1ced cardiac life support," she said . "No
teer what your specialty is, you should be
pared."
ihac's why advanced cardiac life support
, one of the topics covered by the medical
,ool's new orientation program for residents
d in June . Advanced cardiac life support
!S beyond CPR and uses methods such as
ubacion, IVs, and medications to keep the
:ly functioning for a prolonged period after
m failure.
XlhileUB's medical school has offered ad1ced cardiac life support for a number of
1rsand it has been required in some specialprograms, chis is che first time it has been
1uired of all residents in all programs.
lt's virtually unheard of for a schoo l co reire it of all of its residents," Donoghue said.
JB is getting a jump on Scace regulations.
It isn't required by the State yet, but there's
ise chat it will be," Donoghue explained .
ihe new residents were enthusiastic about
'. advanced cardiac training, calling it the
;c part of a fine orientation .
It totally demystified a code," remarked
1ry Ann Millar, M.D.
You definitely need it," added David
:hatko, M.D. "I thought we needed it at

FAI.O PHYSIC IAN AND BIOMEDICAL SCIENTIST

the end of the second year" of medical school.
The orientation was offered through the
graduate medical education program, which
operates under the auspices of the Graduate
Medical-Deneal Education Consortium .
ln order to attend, residents had co arrive
for work a week early and the hospitals agreed
to pay them for an extra week.
"The hospitals are behind it 100per cent,"
Donoghue said.
The purpose of the program was co prepare
the residents for their work in the affiliated
hospitals by educating them on the particular
issues of practicing medicine in New York
Seate, she explained. That includes:
Creating a cohesiveness among the
residents, who work in several different
hospitals.
"They're often confused about their relationship to the Un iversity," Donoghue explained. "They know intellectually they're in
a University-related program, but they hardly ever see anything of che University."
The program also aims co help the residents
gee to know each other . Data suggests that
if they' re brought into the hospitals as
strangers, it takes a week or 10 days for them
co function efficiently. If they know each
ocher, they work in teams from day one, she
explained.
"That may be one of the biggest pluses,"
Donoghue noted.
All of the residents from both halves of che
orientation were invited to a picnic reception.
It was a hot blustery day and the residents
joked and mingled and noshed their way co
peak efficiency.

"It's a good way to get co know each other
before you start the rigors of residency," Dennis Dejesus, M.D., a resident in general
surgery, said of the orientation .
Between sips of an icy drink, Constance
G reene, M.D., a family medicine resident,
noted that getting co know the other residents
was especially helpful to her because she'll be
working with so many of them from different
departments .
Teaching chem to be teachers.
In the past, residents went from being
students co being teachers overnight without
any training. Now they get intensive training.
The small-group teaching sessions and
presentat ions on how co evaluate students
were effective, said Jeff Sceinig, M .D., a resident in surgery. The orientation also
videotaped the students to show them using
good techniques and co point out flaws.
Making su re the residents are aware of
the regulatory climate in New York State. The
Health Department regulations and credentialing requ irements may be much more
stringent than in other states, Donoghue
noted.
"For a person from outside the country like
me, the re was a lot of information," said
Bharat Jain, M.D., who is from India. He
found the discussion on defensive medicine
versus cost control "very progressive."
Even American students are unfam iliar
with things like DRGs and cost containment .
"The nurses would always yell at us about
how much money we were running up with
these tests,"said Millar. "Nobody ever cold us
how much they cost . Now we know."

AVTUMN 1988

�THIRTY
YEARS
UNDERWATER

24

By CONNIE OSWALD SlDFKO
olding
her
breach, the
woman plunges below the
surface of the
frigid ocean
water, swimming deeper
and deeper in
search of abalone, snails,
sea urchins,
and seaweed.
She is one of the Arna - the professional women divers who harvest the
fruits of the seas that surround their
homelands of Korea and Japan. They
may dive as deep as 15 to 30 feet while
holding their breach for as long as a
minute.
Bue what was fascinating co Suk Ki
Hong, M.D., Ph.D., a professor of
physiology at UB, was the Ama's indifference to cold. In the winter, the water
is as cold as 50 degrees Fahrenheit, yet
the Ama would wear only cotton bathing
suits.
About 25 years ago, Hong began co
study the Ama . After a decade of
research, he demonstrated that they had
indeed become acclimatized to the cold,
something that physiologi sts had
doubted was possible.
Hong discussed his findings on the
Ama and his other research when he
presented the Stockton Kimball Lecture
at the Annual Faculty Meeting of the
School of Medicine and Biomedical
Sciences on May 25.
There are 30,000 professional women
divers called Arna in Japan and South
Korea. The profession has existed for
2,000 years, Hong explained, showing a
slide of an ancient Japanese print which
depicts an Ama with an abalone knife

AUTUMN 1988

clenched in her teeth.
Just as their predecessors had done, the
Ama studied initially by Hong wore no
protective clothing, just cotton bathing
suits. Even in the summer, the water
never gets warmer than a cool 75 degrees
Fahrenheit .
"They're exposed to cold all year

round," Hong noted. "I went in the water
to measure the temperature. I wore a wet
suit, but I still felt cold, though the
women didn't seem bothered by it."
Hong and his colleagues estimated the
Ama's daily heat loss to be about 1,000
kilocalories a day. That's an enormous
amount - about a third of their daily
caloric intake.
"This amount of voluntary heat loss is
the largest ever measured in human subjects and provided strong rationale for
our subsequent studies on human acclimatization to cold;' he explained .
The women would voluntarily leave
the water when their body temperatures
reached about 95 degrees Fahrenheit,
Hong said. If asked to stay in the water,
they slowly lost consciousness.
Hong measured the Ama's critical
water temperature, that is, the lowest
water temperature the subject can
tolerate for three hours without shivering. In general, the fatter the subject, the
lower the critical water temperature.
Yet the critical water temperature of
the Ama was low even if there wasn't a
thick layer of fat under the skin, he
found .
Hong also found that the blood vessels
in the divers' hands constricted more
quickly in icy water and remained constricted longer than did the blood vessels
of those in a control group .
Another finding was that these divers
had 30 per cent greater basal metabolism
rate in winter than did non-divers.
All of these factors created a pattern
that indicated that it's possible to become
acclimatized to the cold. But to be convinced, the researchers had to show that
these unique deviations from the norm
disappear when cold is removed.
In 1977, the divers in Korea began
wearing wet suits to insulate themselves

BUFFALO PHYSICIAN AND BIOMEDICAL SCIENTIST

�25

I

Suk K i Hong, M.D., Ph.D.
from the cold. This created the perfect
laboratory for the second part of the experiment. Through a grant from the National Science Foundation, Hong stud ied
the women again and found that by 1982
they
had
indeed
lost
their
acclimatization.
Hong dubbed his talk "Thirty Years
Underwater." His career, devoted to studying humans' adaptation to life underwater, has divided itself rather neatly into
decade-long segments.
In the second decade, he examined the
mechanism
unde rl ying hyperbaric

BUFFALO PHYSICIAN AND BIOMEDICAL SCIENTIST

diuresis, which is the increased urination
that occurs when the body is subjected
to high atmospheric pressure, as occurs
underwate r, for long per iods . T hese experiments were conducted in highpressure chambers in Hawaii and Japan.
The diuresis was puzzling because the
divers didn't increase their fluid intake
to make up for the increased urination,
yet the total amount of body fluid remained the same.
Hong fo u nd that the primary
mechanism for chis diuresis is a suppression of the process called insensible water

loss. Normally, peop le lose water vapor
through their skin. Hong found chat at
higher pressures, the divers lost less water
vapor through their skin.
His third decade of research centers on
explaining, at the cellular level, how the
mechanism causing hyperbar ic diuresis
works . He and his colleagues at UB have
constructed a specia l mini-hyperbaric
chamber to study sodium transport in
cells under high pressure. The experiments so far indicate that high
pressure may indeed interfere with active
sodium transport, Hong said.

AUTUMN 1988

�26

ext
year's
Stockton Kimba ll Lecture
will be delivered by this
year's winner
of the Stockton Kimba ll
Award, John
R.
Border,
M .D., who is
acknow ledged as one of the fathers of
modern trauma surgery.
Border, a professor of surgery at UB,
pioneered ground-breaking treatment
methods that dramatically improve the
chances of surviva l of patients who suffer severe multiple trauma, such as occurs in traffic accidents .
"Few surgeons are recognized as having ch anged a n d imp roved their
disciplines; said Lewis M . Flint, Jr., professor and chairman of surgery, as he
presented the award. "Dr. Border has improved his discipline nationally and internat iona lly."
Several other awards were presented
during the annual meeting. Michael E
Noe , M.D., clinical associate professor in
social and preventive medicine and
clinical assistant professor in medic ine
and family medicine, received the Dean's
Award for his leadership in the Graduate
Medical-Deneal Educatio n Consort ium,
for his leadership at Buffalo Genera l
Hospital , and fo r h is teaching
contributions .
Distinguished Service Awards went to:
Glor ia L. Roblin, Ph.D., clin ical professor of psychiatry;
John W. Cudmore, M.D., clinica l
associate professor of surgery;
John E Moran, Ph.D., associate professor of bioc hemistry; and
Peter Nickerson, Ph.D., professor of
pathology .
The first Robert S. Berkson Memor ial
Award in the Art of Medicine was
presented to James E Phill ips, clinical
professor of medicine . T he award
recognizes a volunteer faculty member
for excellence in patient care and
teach ing.

AWARD-WINNING
PROFESSORS
By CONN IE OSWA LD STOFKO

"Few surgeonsare recognized as having changed
and improved their disciplines,"said Lewis M .
Flint. "Dr. John Border
has improved his discipline nationally and internationally." Border,a
fat her of modem trauma
surgery, received the
Stockton

Kimball

Award at the annual
Faculty meeting.

AUTUMN 1988

BUFFALOPHYSICIANAND BIOMEDICALSCIENTIST

�27

John R. Bord er, M.D.
Phillips said he was very deeply
honored to accept the award in the name
of all the great teachers who went before
him.
he Louis A. and Ruth Siegel
Teaching Awards were presented in
four categories:
The preclinical award went to John
R. Wright, M.D., chairman and professor
of the Department of Pathology. Commendation letters were given to Alexander C. Brownie, Ph.D., professor of
biochemistry; Murray Ettinger, Ph.D.,
professor of biochem istry; Leon E. Farhi,
M.D., professor of physiology, and

T

BUFFALOPHYSICIAN AND BIOMEDIC AL SCIENTIST

Charles M . Severin, Ph.D., associate professor of anatomical sciences.
The clinical award went to Margaret
W. Paroski, M.D., assistant professor in
neurology. Commendation letters were
given to John A. Brach, M.D., clinical
assistant professor of medicine; Ralph J.
Doerr, M.D., assistant professor in
surgery, and Frederick Munschauer Ill,
M.D., research assistant professor m
neurology .
The volunteer award went to
Thomas A. Raab, M.O., clinical assistant
professor in medicine . A commendation
letter was given to Takuma Nemoto,
M.D., research associate professor in

surgery.
House staff and special awards went
to Matthew Antalek, M.O., clinical assistant instructor in medicine; Jon B.
Bishop, M.D., clinical assistant instructor in surgery; Robert A. Gianfagna,
M.D., clinical assistant instructor in
medicine, and Sathyazathi Reddy, M.D.,
clinical assistant instructor in medicine.
Also at the meeting, Mrs . Char les
Schen, president of the Auxi liary of the
Erie County Medical Society, presented
a $10,000 check to the school. The
money was raised by the wome n's auxiliary for scho larships and unrestricted
funds.

AUTIJMN 1988

�28

'DEMYSTIFY
SCIENCE:
GRADUATES
ARETOLD
By DAVID M. SNYDERMAN

B

ecause physicians are the health scientists who most regularly come in
contact with the lay population,
the UB Medical Class of '88 must do their
best to demystify science, according co the
noted evolutionary geneticist Rebecca Cann.
Cann, an assistant professor at the University of Hawaii, was part of the ream char formulated the "Eve Hypothesis~ the theory that
claims that all humans share a common
ancesror. She addressed the 142nd commencement of the School of Medicine and
Biomedical Sciences on May 22.
President Steven Sample also addressed the
graduates, reminding them how much they
are indebted to their parents for making their
college and medical school educations
possible.
The class speaker was Stephen Hughes,
who delivered a farewellco and from the class.
Along with 140 doctor of medicine graduates,
there were 25 doctor of philosophy degrees
conferred.
At the University's General Commencement, held earlier in the day, National Heart,
Lung, and Blood Institute director Claude
Lenfant received an honorary Doctor of
Science degree. Lenfant, who received his
M.D. in Paris, did postdocroral work at UB
during the late 1950s. He did work on
pulmonary physiology under Hermann
Rahn, distinguished professor of physiology
emeritus in the UB medical school.
Commencement speaker Cann emphasized
the need for physicians co be educators. This
need exists, she said, because mosr Americans
lack scientific knowledge.
This knowledge gap is seen in the inability of many Americans co understand scientific theories, including Cann's own research
on evolution.
Cann recently was part of the team which
"concluded that modern humans can trace
the evolution of (mitochondrial) genes to a
single female who lived in Africa around

AlJfUMN 1988

200,000 years ago; she told the graduates.
Known popularly as the "Eve Hypothesis~ the
theory indicates that all mankind shares a
common ancestor.
Cann noted that "mitochondrial genes differ from classically defined genetic systems in
that they are exclusively maternal in their
mode of inheritance; meaning that all of an
infant's mitochondria and their accompanying genetic material come from the mother.

BUFFALOPHYSICIAN AND BIOMEDICALSCIENTIST

�29

A bove, Rebec ca Cann, a memb er of the
t ea m t hat f o rmulat e d the "E ve
Hypot hesis," spoke at th e 142nd comm en cem en t of th e m edi cal sc hool.
evidence of our own evolutionary history better known as biological certainty to the
general public; Cann said . She also noted
that specialists have developed different
"jargons and a vocabu lary that provide an efficient mode of communication benveen peers
but that also provide an effective barrier quite
impenetrable" to understand ing the developments by non-specialists .
Physicians "play an important role in the
struggle for scientific literacy in the Ame rican
public. Your daily activities will affirm the importance of science and techno logy on
B human society today," Cann emphasized .
;
She also noted that many college biology
~ students form their attitudes about science
i very early in life. "These attitudes largely stem
from their exposure to TV and their family
physicia ns; she said .
Cann instructed the graduates to "use your
cited the Office of Technology Assessment's
special ab ility and your everyday working
report for the National Science Foundation
know ledge of the human body to help foster
that states that "somewhere between 43 and
a bette r understanding of the biolog ical
45 per cent of high school-educated
closeness which we humans share."
Americans do not believe in human
In order to help educate as many peop le as
biological evolution and estimates that even
possible, Cann urged the physicians to "read,
about 25 per cent of college educated
travel widely, and talk, not just to your colAmericans hold similar views."
leagues but to community organizat ions,
It is in light of this that physicians shou ld
do everything possible to "make the physical school boards, polit icians, an d lawyers about

i

Mitochondrial genes "code for a small
number of proteins that function in the production of energy for the cell."Cann said the
importance of this is symbolized by biological
essayist Lewis Thomas's statement that "you
cou ldn't lift a finger or think a thought
without those genes."
However, Cann noted, much of America's
population can't fully understand the implications of this type of scientific research. She

BUFFALO PHYSIC IA N AND BIOMEDI C AL SCIENTIST

AUTIJ MN 1988

�30

your informed (scient ific} opinions."
Sample reminded the graduates of the large
debt chey owe their parents for encourag ing
them co pursue an education as well as seeing them through their schooling, both financially and emotionally.
According co Sample, graduation "is an excellent time for you co express appreciation
to the many individuals whose leadership,
loyalty, and support have played such a
significant role in helping you co reach your
goals~
Sample feels chac it is imporcant to
recognize thac "che individuals who are unquestionably rhe most important members of
chis team, and who are deservedly the proudest of all on chis wonderful day are your
parents, who throughout your lives and your
lifetime educational process have provided
direction and support."
His sentiments were echoed by the dedication of the annual yearbook, The Iris, to "our
parents" by rhe student body. The dedication
was presented by yearbook co-editors Lisa
Benson and David Brock and accepted on
beha lf of all parents by Dr. and Mrs. Dav id
Greene, rhe father and mother of a member
of the graduating class.
Brock said that the graduating class decided co dedicate the yearbook to parents "for
instilling the values of caring and self-sacrifice
and nurturing our love of learning; for pro•
viding emotional and financial support and
encouraging us when we needed it most, for
giving of your selves so chat we could give to
ochers and for just being the re."
The class speaker, Stephen Hughes, suggested chat graduates shou ld link their alumni
donations co pet causes.
"For four years we have complained about
our lack of power as medical school srudents;
Hughes said. "Each of us has things in the
curricu lum or about our education we would
like co see improved. I am suggesting thac
when you give - and I do encourage you co
give - you make your suggestions known,
and judge your futu re donations by che
response to your suggestions."
The graduates were welcomed into the
alumn i association by Franklin Zeplowicz,
president of the organization .

AUTUMN 1988

The Hippocratic Oath was administered to
t he new physicians by John Naughton, vice
president for clinical affairs and dean of the
School of Medicine and Biomedical Sciences.
The 165 proud new graduates received their
diplomas and joined the ranks of more than
4,500 alumni.

"This bu ilding is impo rtant if we're going
co continue to develop as a majo r biomedical
research center; said John Naughcon, vice
president for clinical affairs and dean of the
medical school. "\Y/eneed facilities and equipment that will provide for ou r immediate
needs for development and for a possibility
of expansion over a 10-year period or so."

SCHOOL
PLANS
NEWLABBUILDING

T

By LISA JOSEPHSON

J

use when you thought the sawdust had
seeded, the UB School of Medicine and
Biomedical Sciences is planning co
build a $50 million research building that will
contain approximately 150,000 nee square
feet.
The building will be 50 per cent larger than
the Cary-Farber-She rman addition, which
was completed in August 1986. Ir will be
almost as large as UB's Recreation and
Athletics Complex.
The new building will consist primar ily of
laboratory and research space.
The building probably will be located
somewhere co the south of the present
medical school complex. It will connect to the
Cary-Fa rber-Sherman complex, but there is
almost no vacant land nearby, so exactly
where to locate che new building poses some
problems. Valdemar lnnus, UB associate vice
president for resource planning, said the
specific site will be decided by the architectural firm.
Medical schoo l officials are currently in the
process of developing an outline describ ing
what activities will be housed there, said
Innus .
The Ca ry-Farber-Sherman addition, which
cost $19 million, was said to be "the cornerstone of the medical schoo l's expansion
program ."
Alchough medical school officials had
hoped che addit ion would satisfy che school's
needs well into the 21st century, it does not
have the facilities, equipment or space needed for the schoo l co become the major
research institution that officialswant it to be.

he University had planned a major
renovation of the Cary-Farber-She rman complex, but the comp lex doesn't lend
itself to the type of renovation requ ired, Innus said. For example, there isn't enough
room between the ceiling and the floor for
all of the pipes for electricity, gas, water,
sewage, heating, cooling, and ventilat ion . Wee
labs, which use special fume hoods and sinks,
need mo re pipes than office buildings do.
Officials want to hurry the building project along because there's a growing need for
research space in the medical school. To speed
up the process, they've set some guidelines for
construction.
One is chat the new building shou ld be
designed co allow any space to be converted
into wet lab space if needed . Another is there
should be minimal finishes co provide
flexibility.
The planning process is expected co be completed sometime this fall, according co lnnus .
Ac chat time an archi tectura l firm will be
chosen.
The schedu le for construction of the
building depends on the complexity of the
outline given to the architect. Usually co nstruction of a facility of chis type cakes about
three co four years.
Officials say the building could be completed in as sho re as four co five years or as
long as eight years.
"le really depends on how long we cake co
design the building; said lnnus . "Our approach is co move as quickly as possible
through the design process. We will sec ambitious timetables to make the building
availab le as soon as possib le."
"This is an exciting addition chat makes it
possible for us to move forward on plans we've
had for a number of years," remarked
Naughton .

BUFFAIDPHYSICIANAND BIOMEDICALSCIENTIST

�31

Frank Schimpfhauser,
Ph.D. , assistant
dean and director of the Medical School's
Education Development and Research Unit,
received a 1988 Chancellor's Award for Excellence in Professional Service.
A member of the UB staff since 1976, he
has helped his faculty apply for federal grams,
including several subsequently awarded for
research in cancer education and cancer
prevention.
He served as Faculty Senate secretary for
two years and chaired the senate's teaching
quality committee for two terms. He also
oversaw a review of the Gifted Math Program.
Schimpfhauser has co-directed the summer
development program for new and recently
hired faculty for the past five years. He has
published articles on medical education and
evaluation and teache s two graduate courses
through the Department of Social and
Preventive Medicine, where he is associate
professor.
Schimpfhauser holds his Ph.D. and M.A.
degrees from Ohio State University. He
received his B.S. from UB in 1965.

Russell W. Bessette, M.D., D .D.S., has
been appointed head of the Division of Plastic
Surgery at the Buffalo General Hospital and
UB.
A member of the Buffalo General medical
staff since 1981, Bessette has broad clinical
and research experience and an avid interest
in re-establishing graduate education programs in plastic surgery.
Bessette will continue his active role in UB's
Health-care Instruments and Devices Institute
(HID!) as director of the IDEA laboratory at
Buffalo General. He also holds faculty appointments in the Department of Surgery and
the Departments of Oral Medicine and Oral
Pathology at the University.

C h ar les F. Dewitz (M'14) • who practiced medicine until the age of 100, died June
29 at the age of 103.
As a teenager, he worked for one of the
doctors who assisted in treating President
William McKin ley when he was shot in 1901,
and who treated Mrs. Jefferson Davis, the wife
of the president of the Confederacy, in 1903.
Dewitz opened his own practice in 1921.He
closed his office when he was 92, but continued to see a few patients for eight more
years.
He is survived by two sons, Charles S. and
Robert G.; a daughter, Esthe r D. Eddy; nine
grandchildren, and nine great-grandchildren .

Frank Schimpfhauser,

Ph.D.

Peter T. Ost row, M.D. , was moderator for
the 22nd annual John J. O'Brien, M.0.,
Research Symposium held at Mercy Hospital.
He is associate dean for curricular and
academic affairs and associate professor of
pathology at UB.
The patient medication information sheets
written by sophomores Craig Na rin s and
Laura Nic ho lso n were the top entries in the
annual c,ompetition held in the spring by the
Department
of Pharmacology
and
Therapeutics.

Eugene R. Mindell , M.D. , professor of orthopaedic surgery, was named president-elect
of the Musculo skeletal Tumor Society at the
society's recent annual meeting in Minneapolis .
DEATHS

Linda Hawkin s, M.D. , Ph.D. , assistant
professor of psychiatry, received the 1988
Hyman L. Levin Award at the annual luncheon of the Mental Health Association of
Erie County. She is a psychiatrist U and director of the Department of Psychiatry's Education and Training/Medically Ill Chemical
Abuser s Program at the Buffalo Psychiatric
Center.

BUFFALOPHYSICIAN AND DIOMEDICALSCIENTIST

Francis R. Daniels (M'24) • died suddenly
Oct. 20, 11987,from a heart attack at his home
in Sama Ana, Calif. Dr. Daniels practiced
general surgery in Rochester, N.Y., until 1954.
In 1955, he moved to Sama Ana, where he
practiced until 1981. He is survived by his
wife, Irma, a son, Dr. Mar cel F.Danie ls, and
a daughter, Chantal.

Mauri ce B. Gordon (M'34 ) • died on
July 31, 1987, in Brunswick, Maine. He was
superintendent of Cleveland State Hospital
until 1951 when he became director of the
Veterans Administration Mental Hygiene
Clinic in Newark, N.J. Or. Gordon maintained a private practice and served as assistant director of social rehabilitation at the
Postgraduate Center of Mental Health. He is
survived by his wife, Ellen, and daughters,
Marcia and Judith.
Donald M. Secr ist (M'65) • died of cancer
on Dec. 6, 1987. After serving as a captain
in the U.S. Air Force, he began a private practice in gastroemerology in Aspen, Co lo., in
1973 and continued that practice until his
death. Or. Secrist is survived by his wife,
Maryellen; a son, Peter, and two daughters,
Jennifer and Katie.

Georg e W. Fugitt (M'45) • died May 30.
The Kenmore urologist was on the staff of
Kenmore Mercy and OeGraff Memorial
hospitals and had served as president of the
medical staffs of both facilities. F-orfive years
he was chief of the medical staff at DeGraff
and was a member of its board of trustees.
Fugitt was chie f of urology at Kenmore Mercy. At UB he was a clinical associate professor
of urology. H e is survived by his wife, Betty;
two sons, Or. Robert G. Fugitt and David P.
Fugitt; a daughter, Diane Fugitt Pugh; a
broth er, Warren Fugitt, and two grandchildren.

AUTIJMN 1988

�32

TOTAL
1988 AWMNI DONATIONS
SPRING
$77,980AT ANNUAL
REUNION
/CLASS
DAY
CLINICAL

he class reunions are a high point
of the annualSpringClinicalDay held
each year by the School of Medicine 1928
Fromleft, seated: Thelma Brockand RaymondRick/off.Standing:Bmno
and Biomedical Sciences. It's a time Schutkeker
and Walter King.
for chatting about family and mutual
acquaintances; catching up on
classmates'careers,and talking shop.
It's also a time for the traditionalgifts.
This year the anniversary classes
generously donated $77,980.
. $5,750
Class of 1938: .........
$11,460
Class of 1943: .........
$6,900
Class of 1948: ..........
$10,930
Class of 1953: .........
$14,400 1938
Class of 1958: .........
seated:Eustace c. Phillies,Leo]. Doll, Walter z. Schwebel,
$8,725 Fromleft,Lieberman,
Class of 1963: ..........
L.
]. Foit, and \\1/alter
,
ClarenceStraubingerNorman
Samuel
5&gt;·doriak.Standing:Charles Donatelli, Vincent L. Rutecki, Russell].
Cla5S Of 1968: · · · • · · · · • · $7, 575 Catalano,SanfordUllman,H. RobertOehler,Carl Hertz,JohnH. Geekier,
Harry C. Law, CharlesF. Becker,William H. Tatem, Harold]. Elliott,
RichardTerry.
and
$8,200
..........
Class of 1973:
$3,525
Class of 1978: ..........
$515
Class of 1983: ...........
AUTUMN 1988

BUFFALO PHYSICIAN AND BIOMEDICAL SCIENTIST

�33

1943

1953

Fromlefc,seated:Erwin R. Chillag,Kevin M. O'Gorman, Morris Unher,
amd EdmundM. Tederous.Standing:Marvin L. Bloom,PaulJ. Wolfgruber,
Ivan L. Bunnell, Joseph]. Ricotta,CharlesJ. Tanner,PaysonB. Jacobsen,
JohnC. Ninfo,JohnR.Williams,AnthonyJ. Marano,and RobertW. Moyce.

From lefc, seated: Herbert W. Simpkins, Marvin Wadler,JosephF. Ruh,
Thomas E. Comerford,Molly SeidenbergPanner,Jack Gold, RichardJ.
Nagel, and Donald L. Ehrenreich.Standing:Thomas G. Geoghegan,John
N. Strachan, Curtis C. Johnson,John W. Handel, Milford C. Maloney,
Howard C. Smith, Bertram A. Partin, Michael A. Sullivan, Robert A.
Peacock,ReinholdA. Ullrich,RobertS. Sobocinski,StanleyL. Cohen,James
M. Orr, James R. Coleman, FrancisT. Oliver, Donald 0. Rachow,Harley
D. Lindquist, James W. Carlin, and Raymond M. Smith.

1948
From lefc, front row: Lester H. Schiff, Raphael S. Good, Norman Paul,
Albert P.Sutton,Darwin D. Moore,EdgarC. Smith, and CliffordW. Gates.
Secondrow:JamesG. Borman,Michael Dzubaty, Norman Minde, Judith
B. Landau, Oliver P.Jones, Leon Graff, Mary Alice Smith, and David
P. Buchanan.Third row: Warren L. Hollis, Cletus J. Regan, Vernon C.
Lubs, FrancisPeisel,SeymourZola,Daniel J. Fahey,Robert]. Hall, Myron
Gordon,Harry C. Essig,Glenn B. Doan, Ansel R. Marcin, RichardProplesch, B. Edward Heckmann, and Thomas J. Enright.

BUFFALO PHYSICIAN AND BIOMEDICAL SCIENTIST

1958
From left, front row: Richard Romanowski, Michael Mazza, Frederick
Dischinger,GaspareAlfano, RichardRahner,RichardC. Boyle,and Joseph
Bellanti.Secondrow: John W. Float,JohnArmenia,JerryWeisberg,Samuel
Shatkin, Marie L. Kunz, Melvin Brothman,Jacques Lipson, and Roger
M . Baretz.Third row:JosephZizzi, HaroldZimmerman,ReinhardtWende,
Alfred Stein, Gerard Guerinot, Franklin Zeplowitz, Eugene Friedberg,
RichardD. Wasson,John J. Giardino,Leo Kane, Dominic Falsetti,James
S. Williams, RobertC. Dickson, ElroyE. Anderson,John P.Murphy, Lucien Potenza,and Lloyd H. Leve. Fourthrow: RobertJ. Perez,Franklyn
Campagna, Thomas G. Cummiskey, BensonEisenberg,Morton Spivack,
and Michael Genco.
At.rrUMN

1988

�34

1963

1973

Fromleft, front row: JosephC. Tutton,John Schriver,Mike Sullivan,George Fromleft, seated:RobertLaMantia, PaulKuritzky,SharonKuritzky,Jeremy
Lockie, and Joseph Herbstrict.Middle row: Albert Maggioli, Anita ]. Cole, and Stephen Nash. Standing: LeelandJones, RobertFugitt, Patrick
Herbert,FrankV DeLaus,AnthonyFoti,CharlesS. Tirone,David Malinov, O'Connor, David H. Breen, and Joseph Mylotte.
Robert8. Spielman,and Donald Levine.Back row: John LaMar, Richard
B. Narins, William Heyden, LawrenceSobocinski,John R. Fanelli,John
Wadsworth,Jason E. Rudisill, Stephen Joyce,and Ernest Fatta.

1968

1978

Fromleft, front row: RaymondMarlin, Thomas]. Cumbo, Sara R.Sirkin,
RobertA. Milch, BruceGesson,and GeorgeCohen. Middle row: PaulS.
Schulman,Kenneth Jewel, John Gold, Stephen Edelstein,Julian Karelitz,
Harold Kulman, and Kenneth Eckhert. Back row: Peter A. Mansk)',
Jonathan Reynhcut, Lawrence]. Dobmeier,Brian Joseph, Robert White,
and Gerald Daigler.

Fromleft, front row: PaulParoski,Mathew O'Brien, RonaldSomogyi,and
John R. Valvo. Second row: Richard Elman, Gregory Roberts, Roberta
Meltzer, Elizabeth Doherty, Lois Polatnick,Judith Baron-Stone,Franklin
Gillig, and Covia L. Stanley. Third row: Gary Eggleston,Steven M. Seidman,]. Thomas Amo, Mario Santilli, FredH. Geisler,RichardSternberg,
SimonShaham, PaulWopperer,and Nelson Isada.Back row: HarveyGutman, Stewart Altmayer, Stephen Gawronski, and Alan Koslow.

AUTUMN 1988

BUFFALOPHYSICIANANO BIOMEDICALSCIENTIST

�35

1983
From left, front row: Galvin Andmon, Borys Loza, JonathonA. Graff,
ElaineHuber,Sue MeyersTanbakuchi,and FrankMezzadri. Secondrow:
Gwen Nichols, PatriciaFlanagan,Jill Lindner, Andrea Manyon Wild,
SharonAlger, YoungheeLimb, CatherineGood/ell.cw,
and KarenHorowitz.
Thirdrow: Mark Schwager,RichardAmiraian,MelindaS. Cameron,Robert
Smolinski,Stephen Kinsman,James E. Wild, RobertStall, Kenneth Zimmerman, Neal Smith, RichardCollins, Michael Michotek, PeterAccetta,
Kevin Ferentz,John Feldenzer,Carl Grant, Michael Cane, Marc Levine,
and Ronald Marcus.Back row:Allen Rosen,Mark Venditti,and Frederick
McAdam.

NEWOFFICERS
ELEOED
TO MEDICAL
AWMNI GROUP
aul H. Wierzbieniec (M'74) ha s been
elected to a one,year term as president
of the UB M edical Alumni A ssociation.
Other officers are Joseph L. Kunz (M'56),
vice president, and Charl es S. Tirone (M'63),
treasurer. Wierzbieniec, an orthopaedic
surgeon , is clinical instructor of orthopaedics
at UB . Kunz, a clinical assistant professor
of medi cine at UB, is a specialist in interna l
medicine
with
su bspecialties
in
gastro enterology and endoscopy. Tirone is
a clinical assistant professor of radio logy at
UB.
BUFFALOPHYSICIANANO BIOMEDICAL SCIENTIST

From left, Eugene Be l trami, Robert Patt e rson, and Harold
Brod y .

JAMESPLATTWHITESOCIETY
FORMSEXECUTIVE
COMMITTEE
he James Platt White Society has formed
an execut ive committee made up of
society members .
T he purpose of the comm ittee is to help
guide the society in the nurturing of the
medical school, both financially and
emotionally.
Dr . Robert Patt erson ha s been named
chairman . He is joined by Dr . Eugene
Beltrami, Dr . Harold Brody, Dr. Marvin
Kurlan, Dr . Richard Narins, D r. Clayton
Peimer, Dr. Richard Romanowski, and D r.
Robert Bernot.
Membership in th e society is open to
those contrib uting $1,000 to the schoo l an,
nually . Currently, ther e are 66 member s.
Those interested in mo re information
regarding the society can contact any board
member .
AlJfUMN 1988

�36

OCT.13

OCT.20 ...................

T he H arrington Lecture will be held at 4 p.m.
T hursday, Oct . 13, in Butler Audito rium . Edwin
D. Kilbourne, M.D., Distinguished Service Professor
of Microb iology at Mt . Sinai School of Medicine,
will speak . Kilbou rn e is a member of the National
Academy of Sciences .

"Elevated Cho lesterol: A Public Health Crisis?" will
be the topic of a conference sponsored by the UB
Schoo l of Medicine and Biomedical Sciences. It will
be held from 1 to 5 p.m. Thursday, Oct . 20, in Butler
Aud itorium. Registration is at 12:30 p.m . For more
information, call 831-3714.

.

AD IMPLIEDNO ENDORSEMENT
he Buffalo Physician and Biomedical Scientist, Volume 21 #5,
carried an advertisement for Ph ysicians for Social Respon,
sibility that caused concern among some readers.
While we have previously covered the activities of this group,
to which a number of Medical School faculty belong, we had
never before run an ad of thi s nature that invited membership .
Did this constitute an endorsement of the group on the part
of the University, we were asked?
The answer to that, of course, is no.
The ad was run through a misunderstanding on the part of
the Director of University Publications who at that time was func,
tioning as interim editor of the Physician. The ad was brought
in by a faculty member and the interim editor assumed that since
the professor has been referred by the Medical School Office that
referral somehow indicated an approval to run it . This was an
error because when the magazin e appeared, the dean was sur,
prised to see it. In any case, the respon sibility is that of the in,
terim editor and the appearance of the ad was not meant to state
or imply an endorsement on behalf of the Univer sity or the
School of Medicine and Biomedical Sciences.
•

T

��BUFFALO

PtiX§!~~
State University of New York at Buffalo
3435 Main Street
Buffa lo. New York 14214

c.

K.

HUANG BA

57 TREESROOKer.
WILLIA SVILLE NY 14??1

--

Address Correction Requested

Non-Prof
U.S. Po"
PAID
Buffalo.l
Fnm11 N

�Profit Org.
Postage
lo, N.Y.

, No. 3JJ

�</text>
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                    <text>Selections from the Wisdom Mind Series
Read by Gail Sher
(recorded 11 May 2017)
Introduction:
“Between 2009 and 2013 I wrote a series of eight books, beginning with The Tethering
of Mind to Its Five Permanent Qualities, and culminating in The Twelve Nidanas and
Mingling the Threefold Sky that are rooted in Tibetan Buddhist philosophy and dedicated
to “stretching” English in order to create gaps so that Wisdom Mind might flow through
to the reader. The idea in these poems is to not-quite-make-sense. The beauty
(hopefully) of the surface language plus the strategy of “approaching narrative” first
intrigues, then holds a reader, allowing, in stillness, the dawning of a new kind of
intelligence. As a poet, I feel that this body of work is my most important.”

Print source:
Sher, Gail. Reading Gail Sher. Night Crane Press, 2016, pp. 3-4.
File name:
sher gail intro wisdom mind.mp3

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                    <text>Mingling the Threefold Sky

Gail Sher

night crane press
2013

�Y E L L OW

7

�A vein of sun hits a woman’s cheek. What is her
face, she wonders, a blush of cheek beneath the
long hair of her goldenness.
How sunlight fills the sky is how the mind
myelenates appearances to her.
Whose milt is on the edges. It stands in front of
sky such that all she sees is sky.
The absolute knowing of sky, weather and sky, like
a prerogative that’s said against which she may
stroke her child.

8

�Though she sits facing away, as if it is in her, one
feels the age of this away as her.
The painter paints time locked away from its
material, like her own personal face exiled from
her face.
As if away without location is the real time, the real
completion, a recrement of sky, the other loneliness
of sky.
Rangjung dorge’s face. Its light is not what is in me
that way.

9

�As the moon releases into sky, shedding yellow
back to sky, you see a person’s face deep in the
heart of the eye of one.
Day walks out of day losing track of its intelligence,
the part of day held back from day or the end of
his life which is so heartbreaking.
Sound at a distance extends from in front of him.
The arc of his face leaks into shape.
The space between her face, the moon’s display of
face. (The features of her belie her apparent face.)

10

�*
The color of day, two figures in a plain, as if two
were possible outside of itself as a number.
As if day were a point dabbed like paint onto the
brief cortex of togetherness.
A pattern of her in yellow, such that she too,
though he, the he of how they came to be here
forever.
Where clouds are yellow and birds are yellow, a
double portrait of her, which is them as who she is.

11

�It’s like these two things, the way light throws itself
over land, them as a pulse, a stream of apposite
colors.
The metaphysics of grey within a yellow space, or
closeness, the duo of her body coming to be the
grey.
For this she’d received an empowerment. A
doleful space of air. A prosody of air.
The belly of the mind leaks the containment of
them, as how the painter lifts the them of them and
simply puts it on a piece of paper.

12

�Waiting is the movement. Waiting is not resting
because the aspect of pair, a person’s hat of hair,
the tip of the world at the edge of his hair.
The man is not. He is thinking about something
else. His hat facing light holds the tension of his
being there.
The skirl of light obscures to fading light. A vague
sense of waiting hangs over his elbow.
Now he is home listening to its softness as if inside
me I have finally found my bedfellow.

13

�*
The fold of a tree over light on a road, if she is in
the road, the sense that she would be there
anyway.
An old live tree, like the life of someone screaming,
is the language of the tree pushed outside its form.
What colors grow untouched in her, her and her,
what she sees on the Paris streets.
Old registers hard even in a bit of shade.

14

�What is it in a tree that seems to be erased, as if
emotion were space, and the subtlety that is part
of the tree, the great washing over of space.
The way time holds light on the inside of her which
is how color organizes itself toward a person.
It makes me question whether sky is the same
since movement is not limited (I begin to see sky as
limited).
Fifty three skies settle in my backyard may simply
be sky pouring out sky.

15

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                    <text>The Twelve Nidānas

Gail Sher

night crane press
2012

�III
I walk through trees, a series of squat willows, and
see the space between the willows as time.
Because it’s not the space, it’s the emptiness of
mind (whose energy is grounded to its darkest
possible color).
Taking birth beneath a tree, I want to feel my
longing for the tree, my deep thought of you in its
disentangled precision of stillness.
One bends, taking its time, a full earth of time.
How do I wander into its leaf?

9

�Merely touching earth, gently touching the
awareness of earth, like the beginning of day in
earth.
Leaves stretch to sun, the full breath of sun, but I
am left gasping.
My reference point is fading. The underleaf is
blank. But blank itself catches me in a kind of
double-take.
A gap exists but she refuses to see it, which is a
third sort of fuging, like the darkly yellow on the
leaf ’s bottom.

10

�That yellow cala lily, earth and earth-consecutivewith-darkness, a coincidence of blood and dark and
color, such a yellow, heavy and unknown.
Indexed to light, this card of light folds around the
sleeve of your body.
We take shelter in abyss, which looks like a color,
magenta calligraphed in a cala lily’s cup, deep in the
cup, its fire.
Color filters light is not the net color that the cala
lily tells by way of its earth sign.

11

�IV
Night is her skin, its pleats the quiet fold of her.
Background and foreground are the memory of a
skin wearing dynasties of her.
A bird touches night and her skin moves as if it
were tied to this.
As if a mass accumulates in a narrative of space.
Now preserves as a robin opening out of its
capacity in me.
I want to pet it. I want to cry. The intimacy of a
word before it is a word, so that it’s now, in the
interval, wears its own full body.

12

�How many tiers live in a word and the hues of the
tiers in the space of the word’s awareness.
I, the word, in the space of my form, imaging my
form, like a lion in its death throes.
I swallow you and emergence in a word. (The word’s
shape is how death looks like this image.)
A cold press of wind through a word’s tired body
could be hell or a word separate from its word.

13

�To feel into a word, which may be neutral, but may
be like an animal who gets the word, as if the word
were a lesion in its body.
The lesion could be freedom because a word has
no location, like a break in the hills. (Mostly our
words are skeletons of themselves.)
One senses the transparent quality of its body, an
unchangeable power that runs alongside its body.
I am a word. I am the ultimate fearless word,
beauty or sky so that there is nothing in the way.

14

�A word lands on her cheeks. Unspeakable is the
word. Unspeakable is the crutch, the cane of the
word, the transparency of the word that relates to
her as a body.
As how several letters cast a sense of time, like a
painting casts depth, which is the image of death in
a room.
Then the dream of the word amalgamates. First
there’s sky, then the full comportment of a body.
Sky-swaddled words catch the light of death.
I want to believe each word, like pray to the word,
because you want to believe in its denial,
forgiveness, everything.

15

�A word lay in snow. If you lift the snow and
suspend your idea of the possible, it’s like space
linking space to all constellations of that word.
The sheer resplendence of a word, as how the
daughter of a word, a whole lineage pouring out
from its god-father.
A child picks up a word. It’s the enjoyment of the
word, the shape of all commodious expressions
that the mind living in that word carries.
In a tapestry of texts, I am in the moment of one,
as if I had gone to sleep.

16

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Gail Sher

night crane press
2012

�DAFFODILS
A woman alone at a large open window gazes at
the sky. The soft flesh of her arm folds around a
basket. If she is dead, the colors may be alive.
Her soft flesh holds a premonition of her, calls its
form within the form of its space in sky.
She is miming sky with her body. Taming its color,
like a double her of color.
There is a sense of intense activity in the buildings
and neighborhood, so familiar, yet her skin is not
that.

1

�Angst from the street, but what prevails is the face
of a person waiting.
An agony of light chugs through her body.
If she could roll out her body, like make a road of
her body, there is the sense of that being all there is.
As if her flesh were a habit, a woman stands in sky,
catching it in the drape of her dress.

2

�As she rests in the bare window she is dead. I (am
dead) she says. It stands like a point of view.
A strip of death is on the woman’s arm.
She wants the death eagerly, like time tucked in her
arm. On the crest you can just touch death, she
feels.
She sees an arm (the boundless ordinary nature of
her arm) in a gown, in the sky, wrapped in a column
of the unsaid.

3

�Sky like sea, around a woman hugged by sea.
A man is a response (like sky and a sea wall). The
float of him sinks, then appears on the horizon.
I am exempt from sky if I empty myself toward it.
The flaccid man’s ribs absorb the thick musculature
of her arm.
Daffodils range, placated by time, but it is the habit
of deep slumber.

4

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                    <text>The Bardo Books

Gail Sher

night crane press
2011

�Bathing Suit

�A woman begins, is the value of space, like a child
in a pool, shuffling air in which hard wood is air.
She breathes through wood, taking sharp quick
breaths. I want the soft cloth of children, she’s saying.
Her breath has height and the texture of children
swimming, new swim, out and out, yet clearly
touching the bottom. The mind of wood may rest
itself to completion, she murmurs.
Wood and air is swimming there, in the space of
air filtered through a dark forgotten memory.

16

�She is complete air. She tucks herself in air, as in
the taste of breath, the babysteps of breath.
She is anterior to her air and tries to tie air like a
ball.
Someone gives me a ball and I tie up the ball. I feel
certain that I want to tie the ball.
She calls it air because it’s there like air, but
actually it’s a kind of stupidity.

17

�Swimming is like a captivity in its body. Every
minute in a row I am swimming everywhere and
wanting to spend my time swimming swimming
swimming.
Because death, too, is an integer. I say ‘grass’ and it
follows me into longevity.
The absence of time, like grass without time, or a
lizard in its skin but outside time so that its purity
lay in its body.
The brain of the sky snaps an instant to its purity
because everything perceived is Buddha
Vairochana.

18

�My mind vanishes then. Inside its skin it has its
male and female aspects.
A pool of mind is a passage of light, raw light, the
membrane between the watery part of light.
A person flows through wood and is the breath of
a swimmer, like two dead people in love.
Air in a heart is the same air resting there.

19

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                    <text>White Bird

Gail Sher

Q

night crane press
2010

�1
A man wearing birds, sitting in birds, inside the birds’ flow.
Together they’re called White Bird.
White Bird grows tall. White Bird hugs his own legs back.
The meditation of sky streams into his heart so there’s a
passage of heart into which he may relax.
White Bird relaxes back into his heart, breathing white, like
the beauty of a seed or wind in a bird’s hair.
A man sits in wind wearing few clothes, but the birds
come and sit on him like clothes.

57

�White Bird stops. Summer light swarms his shell and the
blue shell breaks.
The beauty of his wing fills with sky.
A gull too drags its sky. As if it were an ear gathering in
sky.
Beauty is sky. Beauty is rain in sky’s past sky.

58

�My mother’s arm is pure, its curve of sky seeping into
structures.
Then later someone says, That person is a dead person. So
then I think, The beauty of sky’s color flows from her arm
reminding me of her arm.
I want to wear sky, I holler. (I am in tune with degrees of
my mother hanging from death like a soft shoe.)
Her yellow armpit sags, like old newspapers would be lying
fallow as they do on distant fields.

59

�A man buys socks but it is really death lurking in sky. I
want to dust sky out so that my limbs swallow themselves.
He looks, passing by death, as if he is new, in sky now, as he
puts it.
O look at the birds! They’re combing each other’s hair! (He’s
watching a bird gather its gorgeousness.)
My mother is a line. Within the death-lines she is one.
But a node on her blackens and then she is not my
mother.

60

�I know a bird whose color is sky before the sky admits
itself. Like the brain of a color if sky admits the bird.
A mountain is visible inside the bird then. Its color dies
then.
A queen bird releases into sky. There’s the sky! someone
says, as if there is sky, the location sky.
That bird knows me well, I’m thinking, because the bird is
mostly dead.

61

�Here is a corner of sky, mother says, fondling a dead bird
wrapped up in her pocket. (The bird had lost sky. That’s
why it died.)
I am the oscillations of a flower, inside, like a flower’s brevity,
she whispers.
A tall bird tumbles through sky. The touch of its voice is
like a raw egg folded into zero.
My mother feeds me air, the tablature of air, doubling air,
forcing it to become air to something.

62

�I dream of air (a box of air) because I conflate air with my
dead mother. She could taste the flavor of the box and in
her mind suck out the box. (Secretly she criticized people
who didn’t suck.)
Her feet swell in air. The ascending foot, like you could
crawl inside the foot.
Who is the end of my mother? Who is the end of my death?
(I am organizing myself backwards.)
Flowers fall, but mountains blossom in air. Born in air, I’m in
air already, like a broken piece of air.

63

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                    <text>Mother’s Warm Breath

Gail Sher

Q

night crane press
2010

�ii
My mother is a place. And a being from there having
qualities, as if she is also from there.
From the inside of her being her, gradually becoming her in the
same taste as russet-pink.
Russet-pink is a field carrying one’s pure essence, like a
whiff, oh! that’s her! Maybe some pawmarks.
Totems of her gaining belly from herself.

83

�A place is by chance (like pain is a guess).
Like a lid with its definite jar, she’s attached to this, thinking
maybe there’s no other jar.
The lid has a slogan, which she wears and thinks it’s not right if
her family does not.
Like a birth word, say. Every person has one word.

84

�Held adrift by old old hearing.
Don’t touch you! says her own face. (For she recognizes the
previous resentment and its marks on her old face.)
As if spring follows summer and we are already at the beginning.
If my father is murdered, does that mean I am dead or (like
one’s face in sound) about to be dead?

85

�A legacy of light is separate from reflection, like a legacy of dog
only sees itself.
So there is mourning but not knowing. She could be a dog
thinking she’s a dog.
Her formless growl cracks like a flower, like shards of voice but
one hears only the thinnest outermost skin.
I harbor myself in the familiarity of something, air, leaves,
peacocks running across a field.

86

�People coming in like the last second of her knowing.
As if she’d snapped her teeth. Stealing knowing, she becomes
simple.
In the interstices of a plan, like knowing skips to what’s
there anyway.
The value of her in the real actual sitting down, till she rests.

87

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                    <text>The Tethering of Mind
To Its Five Permanent Qualities

Gail Sher

Q

night crane press
2009

�ii
A gull circles a wedge of water, marking the water with her eye. The
memory of her skin is limitless, like the memory of her cry, before a
kill or later for the sake of others.
Wind, too, gains qualities by its forcefulness with things, its hand,
say (a piece of sun cut off).
A crack in light, like a painting of light.
The palette of wind is gold, she mutters, the boundary of a man
playing chess in light being the dead person.

65

�A flower emits voices behind falling sun.
A flower is soft and the pain of soft reminds her of a sea of heads.
As if her life dreams its own violence. If a bird disappears, she may
have asked for this to happen.
She begins to think that mountains wash out mountains. That
the sea of heads form a land on which to walk, which she calls the
isthmus of larks.

66

�So a bird flies flat and what is it about its sleek blue mind.
Is a bird a bird or quality of place dawned by the bird? you mutter.
You look at a chirp, though it could be surreal. A tree comes just at
the point of sky.
Phenomenology of the tree rides not so much on the stature of the
tree but like the tap of a cane, where it goes after it is hidden.

67

�A sycamore branch in late light sheds, as if sun splashes scattered
shards of larks through needles of light-fall.
Time is little drops like from a spout drip-dropping the bough.
Its stem is underground, someone says, and I have a memory of a
double stream flowing deep beneath the earth.
You tap on the stream to awaken the stream so that the leaves stop
shaking their light out of it.

68

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                    <text>though actually it is the same earth

Gail Sher

Q

night crane press
2008

�Tiger Dream
Sun from behind the mountain falling on the
threshers and reflecting from the lake gains
depth from the sound of falling.
The sound of water over stones at the lake’s edge is
like a darting bird.
If she wakes, she couldn’t say the bird disappears,
but its breath dissolves, like an undertow at sea.
How igneous (fiery) and lucid are the bodies of tigers,
she muses.

21

�Commentary
Each day the sun slips over the crest of the hill and
lights the yellow grass.
A cat climbs the hill as though dawn were in its
head, entwining pieces (petals in branches).
A day-moon slides below low tide. Fall-out from
one’s skin protects it from further harm.
Tide emits tide as she wanders down the coast,
empty as a battered jug.

22

�A woman carries a jug dexterously embroidered on
silk. The woman’s skin shines like the interior
pink of a river.
The dimensions of the jug’s magenta is implicit yet
exacting.
Out is not a direction but an aspect of conference
around the jug’s battered aggregates.
Bringing yellow out, where out is a structure of color
and light, intensifies out, as if its DNA changes.

23

�There is an hour in which her memory will be there,
where light falls in rain on a tiger’s flickering
head.
A stone woman prays, hearing sun in sun. (She
dreams its precise nest.)
A magenta flower glows so that I feel free at last. A
magenta flower glows, disappearing in its skin.
Light jumps back as if she has that person again.

24

�Death is color-added-to-color.
Color learns color by touch, like the feel of rain from
one’s bed.
What if the occurrence of harm refers to the
difficulties of offering the harm? In the broad
space of an animal, a wound in a woman’s
thumb feels like embroidery of jasmine and
honeysuckle.
The necessity of something and its form is the tiger
sleeping, tail to tail, in tandem with something.

25

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                    <text>Mary’s Eyes, a new voice in the radical language experiments
Gail Sher has been exploring since 1981, joins the ancient
passion of devotion to the cutting-edge linguistic so
characteristic of her work.

In addition to her poetry, Gail Sher is the author of One
Continuous Mistake: Four Noble Truths for Writers (Penguin),
the first of a widely-praised series of books on the craft
of writing, informed, as is all her work, by the practice of
Zen Buddhism, Tibetan Buddhism and Yoga. Her poetry is
archived in the Poetry Collection of the University at Buffalo,
library.buffalo.edu/collections/gail-sher. For more information
and to read her poetry online, go to gailsher.com.

Gail Sher Mary’s Eyes

�Mary’s Eyes

�Also by Gail Sher
PROSE
Reading Gail Sher
Poetry, Zen and the Linguistic Unconscious
One Continuous Mistake: Four Noble Truths for Writers
The Intuitive Writer: Listening to Your Own Voice
Writing the Fire: Yoga and the Art of Making Your Words Come Alive
From a Baker’s Kitchen
POETRY
Elm
Early Work
Pale Sky
Five Haiku Narratives
Ezekiel
Sunny Day, Spring
Mingling the Threefold Sky
The Twelve Nidānas
Figures in Blue
The Bardo Books
White Bird
Mother’s Warm Breath
The Tethering of Mind to Its Five Permanent Qualities
The Haiku Masters: Four Poetic Diaries
though actually it is the same earth
East Wind Melts the Ice
The Copper Pheasant Ceases Its Call
old dri’s lament
Calliope
Who, a Licchavi
Watching Slow Flowers
DOHA
Birds of Celtic Twilight: A Novel in Verse
redwind daylong daylong
Once There Was Grass
RAGA
Look at That Dog All Dressed Out in Plum Blossoms
The Moon of The Swaying Buds
Marginalia
la
KUKLOS
Cops
Broke Aide
Rouge to Beak Having Me
(As) on things which (headpiece) touches the Moslem
From another point of view the woman seems to be resting

�Mary’s Eyes

Gail Sher

night crane press
2018

�Copyright 2018, Gail Sher
gailsher.com
All rights reserved
Night Crane Press
1500 Park Avenue, Suite 435
Emeryville, California 94608
No part of this publication may be reproduced or
transmitted in any form without permission
in writing from the copyright owner and publisher.
ISBN: 978-0-9978313-2-0

�For Brendan

��contents

Mary’s Eyes 1
Sing 13

��Mary’s Eyes

��i
cold and snow. the sound of snow falling. the young
novice’s eyes
it’s (the) forgiveness that she notices
(an old noticing) she feels
thinks about Christ. will she marry him. she has already
married him (she feels)
asks if she is sure

[bells sound in the background]
figures appear. the clink of plates, spoons,
hush of nuns eating
the rule of the meal (omitting) the meal
the weight of the prioress’s eyes
readings turn to time (the word Mary repeated)
verse empty of her suddenly

3

�ii
a tall girl and her girl (their “astrology” of brotherhood)
the eyes of one watching from a second-floor window
what the watching girl is thinking versus the couple—
walking, carrying books, talking
loneliness and time. more loneliness and time
“crippled time” she muses opening the sash for a better
view
as if time and her ribs—as if time stopped her ribs
“see” she presses placing a hand on one
a girl within the girl arrives behind the color orange
“break it” she is yelling, throwing food at birds
(she is always throwing food at birds)
“grandpa fed the birds” she explains
she says “the” as if the birds were his or always the same
(or something)
“the” (the article) making the thing “definite”
pinning it down like a thumbtack

4

�orange and birds all curly like his hair
mishmash of thoughts underneath
grandpa’s car, intelligence, newspapers, noise
the grinding of sound inside his head
[inside her the smear of his aloneness or what must have
been his aloneness]
maybe he felt the birds would understand—if they would
die or if HE would die
“my feelings belong to sky
they go up and are swallowed by sky” he would rail
(being a person inside out or that his gravitational pull was
wrong)
as if words were too tight for his body
or that he’d say, but instead of words there’d be sadness
“the infant Jesus screams
can’t you hear him screaming” he’d cry
(actually I think I did hear)

5

�iii
lines &amp; squares, the enchantment of their honesty
the certitude of straight untarnished by thought
carves one on her thigh like a symbol of something
important
then forgets the thing that was important
the mark (tattoo) is blue
stands for Christ’s feet that eventually turned that color
the turning of one color into a second color
the brown of his feet still in Mary’s eyes
the transmutation of space infected by what happens in it
or the imbuing of a form with the means of a previous
form
touches a line forcing it to speak
to say what she forgets (because she really can’t
remember)
the violence of gone (actually gone is impossible)
what is its shape before it becomes its line
or if the line is an amulet holding (probably-irrational)
reverence
beauty this thorough
6

�the image of his feet nailed to the sun
its ball of red rising
[here the landscape becomes an action that moves
aggressively toward her]
cups her ears so that it’s paused
thinks of the letter F then E E and T
summoning them to her so that she is not alone
“with a letter I can be WHEREVER I want
when I hold one in my mind I forget everything else”
[the alchemy of WHERE versus the unawareness of a leg
(for example)
as if the leg were a mermaid’s rubbery tail (i.e.) a memory
from the past trying to be from some other past]
“maybe words are stars secretly” (she is thinking)
turning one around (handling) it carefully
because lightly let go a word suffers
“words glitter and shine all by themselves in the middle
of the night (seemingly)
like a winter star all by itself (hanging by itself) seemingly”

7

�interlude
alone in an open room
water and wind (their) hardness in time
wearing out time replaced she feels with time
the freshness of wet blows around her lightly
[her sense of the sea (awareness) of time (her presence in
the room) co-adjacent with time]
her dog too on the rug below
one eye opening then closing (seemingly) content
the sand covering its body and what the sand says about its
life
the dog’s ear and what the dog is noticing (waiting) for
something to end
sees the waves of the sea melt into sea
its song vanishing to nothing
the rhythm of the vanishing repetitive (prayerful)
the earth (too) which the sea hears

8

�listens to sea (the sound of the sea breathing) the
implacability of sea time
its power and its blueness circling her like a tiger
the tiger’s immaculate stealth

9

�iv
blue late-April sky, sound of waves lashing
the girl’s jaw remembering something ungraspable
the sea itself ungraspable
thin (soft) time which she dreads
the coming of harm, ripening and then, moonlit
coming to know (coming being its own naked color)
“soon” she thinks but it’s vague
the upshot of vague like a portion of a color
notices sky, a shadow of a tree, the mind of the tree
transferred to a form
what the form may imply and whether or not she
generalizes its significance
reads the clothes for clues

10

�sees Jesus in his robes rising a little (bowing) toward her
(slightly)
sees herself seeing the vivid reality of his form
the body of Christ (touching) it with sight
(its) aperture and tone with regard to so much happening
the event—Jesus rising—and then again rising—
“toward her” had been there the first time (she is realizing)
as if his life took place
(in her mind a lion yawns)
[but it’s clapping. someone is bowing to an act seemingly
ended
the impossibility of blue (since it stands for itself) ending]
authority of blue (standing for itself) attentive (to) what we
call color
which may have taken place previous to time or even in
some other time
“what is my color before there was color”
ransacks blue as if it were light instead

11

�she is what one is inside of
drawn to what is known
also sense of fallowness
even her hair as if once it was some other color
such that it’s cheap
the slut factor of hips
seeing the calling flammulated then, covered with feathers
her name flying away
away = coherence (as in food afterwards)
the aura of a plate lingering there
but in her mind it’s the girl’s blue-feathered shoulders
“an owl at night, me the shrew”
her shrew has no snout however

12

�Sing

��i
a cow hangs toward the end of sky
its green moo dead
(a social cow) the archer thinks
splotches of blood recede into sky
his bow too recedes
holds feelings of cow
cordons off sky so that cow can rest
“wipe the blood off ” someone says
the cutting of time as if time comes in the slow tones of a
woman
the subterfuge of having it
leans into seriousness (as if) time is a joke then “getting”
the joke
“what about eggs” someone says, pretending time is a
koan

15

�“mind may eat without time
mind may eat with neither food nor time”
(as if food were time told by the throat making her have
some)
pleading YES as a motion
citing this or that as others pass unnoticeable in her mind’s
eye
intends again, to eat (again)
[a fool eats in slow-motion footage, reel continuous
maybe something crawls out of tight dark space]
the bag of her (she feels) socks in a silly pile
burglars appear. what should she do
is someone there. am I there
police fence her yard barring her off, warning her
probably. hoarding occurs probably
+ images of climbing—there’d be rain—without
footholds, without grab-able bars

16

�reflected in (slight) convexity of ovary area
(eating) off the knife, laughter off the knife
the pregnancy of knives, cans wrapped in paper or things
wrapped in whitish paper

17

�ii
a bluebird’s song and then the sky afterwards
propelled through time as if they were together
blocked by shade, the shade carrying light anyway
(its bullying white getting in anyway)
its white versus ordinary white
white releasing white such that the white of white is freed
(white separate from “white”) releasing significance nonverbally
white without releasing significance
[having freed a color (separate from freeing)
refers to alaya of existing
like the black part of white such that snow exists for
black also]
scabs of snow on tree tip also
the way it bunches on a branch, a bird in the branch
if it moans (in the extreme heart of a woman)

18

�“the sound of snow could be air weeping”
as if music were there but then it is over
“over” as an idea
turns into sky, the gray of mouths opening
sings sky forward into treetops
the method of sky, voice, snow in choral time
no sound but sky
the liturgy of sky (and before sky)
mimes the One in a row
silent canticles in a row

19

�iii
moments of snow devolve into blue
asleep to itself as if its brain were blue also
slow (into the basket)
slow into her (as if) trees are following her
but the trees are narrowing up to her
she will be a bird (she is saying)
an ultra bird thought by one in pain
one bird walks from shadow into shade tipping the balance
slightly
one bird versus no bird or if the bird doesn’t sing or fails to
sing
creates an absence of the bird
loops of birds fight
wears necklace of birds-in-a-row fighting
wears necklace of birds-in-a-row dead

20

�an abstract bird clears in her mind
[GEORGIE but her voice is slack]
solemnly (solemnly) ice + the vague marrow of its bones
“was there time”
like a swan (leaves) its name in the air
feathers &amp; bones mute
“lay dead, lay dead”
snips time touching its feathers
“poor Georgie” said (a bit bleak)
sings in wind (adds it to the bird)

21

�iv
[fades to black winter lake, swan (in it) swimming
the midriff of the lake (its) hollowness in space]
“look a crane” someone says taking out binoculars
she turns to see the crane but SHE is the crane
the hood of her head covered with snow
offers condolences to her but SHE is the one offering
condolences
“cranes are always offering condolences”
dancing in snow with their tracheas screeching
bony rings rattling
the emblem of her throat arched high in the full moon
escutcheon of moon with medallion of her throat
sings to moon which she feels is SO watching
(hopes to hear the moon)

22

�the sound of a thumb presses back softly, the silence of a
thumb in the pit of her stomach
the sound moves to her throat
its thumb speaks in her throat like a second throat
aware of a thumb as a mouthpiece of pressure
sees with her mind it being in a grave
the lowering of the thumb (loaning color to earth)
frill of snow covering it up
[a drawing of the thumb:
graphite on paper 1963 is written near the bottom
the writing is cracked though]

23

�Mary’s Eyes
is set in Minion, a typeface designed by Robert Slimbach in the
spirit of the humanist typefaces of fifteenth-century Venice. Minion
was originally issued in digital form by Adobe Systems in 1989.
In 1991, Slimbach received the Charles Peignot Award from the
Association Typographique Internationale
for excellence in type design.

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                    <text>Gail Sher interviewed by James Maynard,
Curator of the Poetry Collection at the University at Buffalo,
Emeryville, California, March 19, 2018

JM:

Well, to begin today, this is Jim Maynard, Curator of the Poetry
Collection at the University at Buffalo, home of the Gail Sher
Collection, interviewing Gail Sher at her studio in Emeryville,
California on Monday, March 19, 2018.
Gail, we are having this conversation at what I think is a very
interesting point in your writing career, in that you have recently
been consciously reflecting on your development as a poet and
reissuing some early work, while also, simultaneously, producing
new writing, which I know you do on a daily basis. I think this
provides us an excellent opportunity to talk about your poetry and
poetics, as they may have changed over time to where you are
today.
After studying music for several years, followed by undergraduate
and graduate work in English and Middle English, and then 11
years of practice between Tassajara and the San Francisco Zen
Center, you made the conscious choice to focus your attention on
writing. Your first published poems appeared in the magazine
Credences in 1981, followed a year later by your first book, From
another point of view the woman seems to be resting.
Since then you have published a total of 37 books of poetry and
several works of prose, including in 2016 Poetry, Zen, and the

�Gail Sher-James Maynard
Page 2

Linguistic Unconscious and Reading Gail Sher. Both of these, and
especially the latter, provide your readers with a remarkably useful
set of contexts for exploring your work and its “habitats,” as you
say. And my questions here today in many ways depart from these
two texts.
In Reading Gail Sher you describe your work in retrospect as taking
shape in four phases: Radical Language Experiments, 1982 to 1997,
Asian-Influenced Work, 1997 to 2008, the Wisdom-Mind
Collection, 2009 to 2013, and Late Work, 2014 to present. When
discussing the first, you write that early on you realized that your
“concerns” as a writer were “of a poet, not a novelist, short story
writer, or essayist.” And that you “came to understand that [you
were] a poet because [you thought] like a poet.”
What I wanted to ask you first is, what does it mean to think like a
poet?
GS:

Poets care about language. That may sound simple, but it's a life's
preoccupation. So when I hear anything, even you reading that
introduction, I hear the particular choices of words, like you used
“depart” in an interesting way a few sentences ago. And there will
be rhythms that are particular to who you are as a person and
onomatopoetic inflections that typify who you are and where you're
coming from. And that's what I hear.

�Gail Sher-James Maynard
Page 3

And then later I'll go back to the import of what you are saying,
which is what most everybody else would hear. It's like a giraffe is
oriented in the world in a very different way from a lion. And I'm
like a giraffe, in the sense that I just don't function, I don't receive
my experience in the same way as other people. And it's a constant
problem.
JM:

Well, the word that keeps coming up for me, and I think I'll come
back to a couple of times in these questions, is attention, which I
can't hear the word attention without also hearing the word tension
inside of it. So based upon what you just said, then, how would you
say poetry, then, differs from prose or fiction or nonfiction?

GS:

Well, I can't speak for poetry in general because I don't think all
poets come from the same place. And I'm not saying this place is a
better place to come from. I'm saying I can't help it. It's just like
who I am. But it differs in the sense of a novelist is thinking about
character development and ethics and who is going to fall in love
with whom, and who is going to reject whom, and how subtly all of
these things take place in society. None of those things are my
concern.
In fact, in my poetry I have to bend over backwards to leave the
story out so that people will pay attention to the language.

�Gail Sher-James Maynard
Page 4

JM:

That brings me to my next question in terms of thinking about
language, in hearing it first before understanding, as all good
giraffes do.

GS:

Right.

JM:

I know from early on you were very actively engaged with music,
having played piano and harpsichord and having studied music
theory and composition. How do you think these experiences may
have shaped this thinking about poetry and, in particular, your own
reimagining of Eastern literary and musical forms from your Asianinfluenced work?

GS:

I actually formally gave up music when I was a Zen student at
Tassajara, so that I could use all of my musical ability for writing.
And I believe that I do do that. And it's only been in the last few
months that I've taken up a musical instrument, but it's also only in
the last few months that I've consciously ended my career as a poet.
And in order to emphatically do that—because I did that once
before and it didn't work; I ended up writing yet another poetry
book—so I decided to write a novel.
I used to hate poetry. And, in fact, I distinctly hated poetry and all I
read was novels and literature that wasn't poetry. And so when I
took up writing, my idea was to be a novelist. And I only had to
learn later by default that my interests just weren't that of a novelist.

�Gail Sher-James Maynard
Page 5

And so now you're probably wondering, "How can I write a novel
then?" Well I hired a tutor and I'm taking lessons.
JM:

So have you found yourself, then, inverting what you just said?

GS:

No. What I'm actually finding is that the lessons are completely
boring, and I can't do anything that they're really asking. And I've
got it down to sort of the way they've got it organized. And so I just
flip to the back page and I read what the assignment is, and I hand
them not the assignment, but I hand them what I've written already
in between when they read my work the last time until I'm going to
turn in this batch.
They really want my next chapter and I'm really sending them an
array of pieces that sporadically cover, basically, what this story is
going to be about. It is not really a story, actually.

JM:

So how do you feel having so long tried to suppress that narrative in
your radical language, to now be jumping in that side of the pool?

GS:

Here's what I really think. I think that the best novels are actually
poetry anyway, but they're not language-based poetry. They're more
maybe rhythm-based poetry or meaning-based poetry, which I have
never written. So in a way, you could say I'm just writing a different
type of poetry. But this is not my passion. I better stop and say
something else. And this may be because you haven't gotten to the
Wisdom Mind part yet.

�Gail Sher-James Maynard
Page 6

JM:

My next question.

GS:

Okay. Well, I'm going to answer that question right now. That's
really important. It's why I can stop. It's why I can officially say I've
done everything I set out to do as a poet and I don't need to do it
anymore. What I set out later to do as a poet, when I realized that it
was my job and it kind of fell to me to do, uniquely, because of my,
not only Zen background, but even more particularly Tibetan
Buddhist background, I became aware that other languages like
Tibetan and Sanskrit have the ability to convey wisdom in such a
way that English can’t.
For example, in Tibetan there are 15 words for love, and in English
there's like one. So I set for myself the poetic task of enlarging
English. So I feel like what I've accomplished as a poet, primarily,
is stretching the English language. And the way I've done that is by
leaving meaning out, but using language so that it implies a
meaning, that it makes you think there's going to be one there any
second.
So if you sit with a very open mind, almost like a meditative mind,
and read my Wisdom-Mind poems, you will find yourself going
beyond the language into some other place. And that other place
could be a wisdom-based place which is beyond language; whatever
it is that's beyond language. And that's what I've strived to do. And

�Gail Sher-James Maynard
Page 7

by the time I got to The Twelve Nidanas, I felt like I had done that
exponentially.
The Twelve Nidanas takes place on about five different levels. And
I felt like I was never going to do it any better than that. And there
are a number of books leading up to The Twelve Nidanas, and
there's one that follows it that's sort of a coda [Mingling the
Threefold Sky]. I felt like I don't need to do this anymore. This is
really, really hard. And the pitfalls are, since it doesn't quite make
sense, it can also sound like nonsense, or it can sound silly or
something like that. And that's not what I was after.
So I had to toe this really careful line to neither be silly nor
nonsensical, and also not quite make sense, so that the reader would
make his own sense, but beyond language sense.
JM:

This always reminds me of, I think you find it in both Eastern and
Western discourses that there is this long-time animosity between
poetry and philosophy. That poetry makes a kind of experience
possible. That philosophy wants to valorize and describe.

GS:

Yes, that's right.

JM:

But in describing it it cuts it off from its life force.

GS:

That's right. Because wisdom can't be described in language.
Wisdom goes beyond language. So that's where my way of being a

�Gail Sher-James Maynard
Page 8

poet can do that. If you were like a novelist you wouldn't be able to
do that, or if you were a regular poet who talked about anything.
Really, I'm not talking about anything. I'm making something
happen for the reader by the way I use the language. So I'm
distinctly not talking about anything.
So when I stopped writing that kind of poetry, the first thing I wrote
was Sunny Day, Spring, which is way more prose-like. But what I
loved about that book is that I said to my friends, "So it's 113 pages
and it doesn't say anything." And so I was very happy about that.
But then later I was still determined not to write poetry.
And then I wrote Mary's Eyes, which, actually, I'm very fond of that
poem, and it is a poem. And it took a year-and-a-half to write those
22 measly pages. But it's unique in a completely different way from
my other poetry.
JM:

Just hearing you speak now I'm reminded, too, of the great Cage
line, "I have nothing to say and I'm saying it."

GS:

Right, right. Yes.

JM:

This notion of interrupting the mind's habitual activities of sensemaking, that, for me, when I talk about that as a reader, both your
attention and your use of tension, that's the tension.

GS:

That is the tension, right.

�Gail Sher-James Maynard
Page 9

JM:

This demarcation between making sense, but deferring it, and kind
of going back and forth.

GS:

Exactly.

JM:

So this space for wisdom that can be possible through language, do
you think of it as a non-conceptual type of knowing?

GS:

Yes.

JM:

It's hard to talk about outside of its performance, but could you say
a bit more about that space?

GS:

Well, that space, what got me started on that was the 12 years I
spent, or 11 years or whatever it was at Zen Center sitting a lot of
zazen and feeling at the end like, ugh, this is a total waste, basically.
And then later I had a glimmer, actually. When I was at Zen Center
I actually had a glimmer of, "Oh! I know what this is about. This is
about the body. The body is what is understanding here. If there's
anything to be understood you do it with your body."
I had flickers of that when I was at Zen Center, but nothing like that
was ever talked about, and so I never dwelt on it. But later I realized
for absolute sure that it was the body that understood Zen practice,
and that I actually had gotten everything. I actually had gotten
everything. And I feel that was later confirmed, and I won't go into

�Gail Sher-James Maynard
Page 10

that story. You asked me how Zen practice and Tibetan Buddhist
practice informed . . .
JM:

Uh-huh, and just to hear you talk more about this, what I think of as
kind of a non-conceptual or non . . .

GS:

It's not conceptual. My first glimmer into non-conceptual came with
the understanding that it was the body that got this kind of
knowledge. And then my second, not just glimmer, but in depth
round of it came with Tibetan Buddhist spiritual practice, which is
very emphatically non-conceptual. And there's a huge portion of it
that's just simply rote practice. Like to do the ngondro, which in
Tibetan Buddhism you aren't even given your first anything until
you complete what's called the ngondro.
And each lineage has its own ngondro, so there are different
ngondros. But the ngondro that I was given has five practices that
you repeat 100,000 times.

JM:

Wow.

GS:

That's a lot. It took three-and-a-half years. These are called
preliminary practices, before you even get to the first real practice.
And so throughout all of that, and then also finally getting to the
real practice, one gets a feel for where this wisdom lives. And it's
that that I was working with in the Wisdom Mind series.

�Gail Sher-James Maynard
Page 11

JM:

Do you think there is a connection in any way for yourself between
writing and Buddhism and psychotherapy? Is that too much of a
leap to make?

GS:

I would say the connection is there, but it goes from Buddhism to
psychotherapy, and Buddhism to writing. I don't know that it goes
full circle like that. Buddhism, definitely, informs my
psychotherapy practice, absolutely 100 percent. More so than any
theoretical model or this and that. It's informed me and I'm the tool
for psychotherapy and that is how I work.
And so not everybody likes me and so be it. But the people who do
really do and their lives really change for the better, and I see it
every day. And Buddhism informs writing in the way we've already
talked about, like this whole Wisdom Mind thing. I don't know if
there's like a circle there.

JM:

But it sounds like Buddhism is the key.

GS:

Buddhism is the key. But I've practiced Buddhism at least 40 years
pretty intensely. So you can't be that intense about something and
not have it be in your blood. It's the way I live, really.

JM:

That kind of study must re-hardwire your brain and your attention
patterns.

�Gail Sher-James Maynard
Page 12

GS:

It does, even to this day, when I'm not doing formal practice
anymore. I made a conscious decision to just accept that writing
was my way. And poetry is a Way with a capital W. And so I
finally came to peace with that.

JM:

Thinking about poetry as a Way, I've heard many writers talk about
their feelings, however sometimes vague, that all of their books, no
matter how different they may be from one another, are somehow
all part of an overall or overarching continuing project that they see
taking shape through different parts or fragments. As we talk here
today, do you have that sense of your own trajectory as a writer, or
do you think of these four phases as distinctly separate periods of
your work?

GS:

No. I definitely have the sense of them building, and then
culminating with the Wisdom Mind series. And I feel like that
book, The Twelve Nidanas, is the culmination of my writing
practice, plus the one right after that [Mingling the Threefold Sky].
And from there, I decided to just have fun after that. The only book
that I would put in a serious poetry category after that is Mary's
Eyes. The others [“Late Work” 2014-2016] were just fun and I'm
doing fun now.

JM:

I'm quite fond of Mary's Eyes. I think through the language there is
a real construction of a space for contemplation in that book that I
find quite powerful, actually.

�Gail Sher-James Maynard
Page 13

GS:

Thank you.

JM:

Almost in an artistic sense, in that there is something almost
dramatic about it. It's as if you're creating a stage for something to
happen, for something to take place, a performance.

GS:

Yes, I was. That voice is different from all my previous work. And
that's what I'm so pleased with, that it is distinct, and that I felt it
was successful. But it took everything out of me, and so I'm writing
a novel now.

JM:

And here's a question that I've actually wanted to ask you about for
a long time. I've always been struck at how across your work these
37 years I keep coming back to use of parentheticals. And in
Reading Gail Sher you say the “parentheses don't contain, they
shield.” And then quote Kathleen Fraser on their ability to
destabilize a text. Could you talk a little bit more about your use of
these parentheticals in all of your work as both sheltering and
disrupting something.

GS:

Correct. And, interestingly, for the very first time in my whole
writing career, in my novel, I'm not using parentheticals at all. And
every time I'm tempted to, I go, "No, no. It's not right." Isn't that
interesting? It's interesting to me. I think parentheticals were right
all the way from my very first work. I bet you, when we discover
that first piece, whatever it is.

�Gail Sher-James Maynard
Page 14

JM:

We'll track it down.

GS:

I bet you're going to find parentheticals there.

JM:

Well, I read them all so differently. Sometimes for me, as a reader,
they give a multivoicedness to the text, as if there's a different voice
speaking. Sometimes they have a tendency to shift the point of view
from an interiority to an exteriority.

GS:

Yes, correct.

JM:

And sometimes they seem to shift things altogether in terms of
register and tone and voice.

GS:

It does all of the above, yeah. I know. That's why I'm shocked it's
not happening in this book that I'm writing now. It's not happening.

JM:

Well, I'll be curious to see how the novel ultimately ends up. In
addition to always being interested in your use of parentheses, from
the first time I read it my absolute favorite line of yours from
Poetry, Zen and the Linguistic Unconscious is the following: "My
biggest responsibility to myself as a poet is to remain in the realm
of the unknown."

GS:

Yes.

�Gail Sher-James Maynard
Page 15

JM:

"I don't write from an idea or concept or from any other analytical
place. My writing arises, and I am constantly surprised by it." Now,
I have to admit as a long-time reader and enthusiast of Robert
Duncan's, this seems where you and Duncan are almost sitting in
the same chair together. And this, certainly, I think, has many
indications for thinking about the Buddhist element you've been
talking about, as well as the psychotherapeutic, but could you talk
about writing as a process of discovery?

GS:

Oh, yes. That is what it is, which adds another dimension to
everything I said about the Wisdom Mind series because it is about
the unknown. And even in doing it, you're dealing with that every
single day. I don't have this difficulty anymore because I've been
doing it for so long, I think. But I know for my students the hardest
thing is to keep them not knowing because they want to know. "We
have to have a plan for this and we need an outline and we need dada-da-."
And then I tell them, "No, no. Just stay where you are and just see
what happens." And they'll say yes, and then the next time they
come in they'll forget they said yes and they'll go back to, "Well,
but you know, I can't figure out . . ." But it takes place on a whole
lot of levels. There's that level of what's going to happen next, so to
speak. But there's also the level of just the mystery of language and
your psyche and “allowing” in silence and allowing space for
anything to happen.

�Gail Sher-James Maynard
Page 16

Not to mention, a skillset that's developed over many years. And
then you put all that together in a set period of time on a regular
basis and something does happen. Mary's Eyes just happened
though it took a long time. Something does happen. I almost can
say that it's just impatience at this point that keeps me from—I'm
sort of almost tired of sitting there. And I'm still sitting there--and
more is happening.
JM:

Duncan has a great line for it. He calls it the intellectual adventure
of not knowing.

GS:

That's right. That's good.

JM:

But it's difficult.

GS:

It's very difficult. It's like the artist's blank page.

JM:

Well, I think of Dickinson’s “I dwell in possibility,” or Keats’s
“negative capability.”

GS:

Yes, negative capabilities, exactly.

JM:

This is something that poets and artists come back to quite a bit.

GS:

Right.

�Gail Sher-James Maynard
Page 17

JM:

I'm hoping we've got time for just a few more. I know we've been
talking a lot about more theoretical considerations and your
approaches to poetry and language. And I wanted to take a minute
or two to talk about what your practice might have looked like in
the past or now. You've talked a bit about exercises and activities as
a way of preparing oneself to write. But for yourself, how does a
poem begin?

GS:

Oh. It doesn't begin. The whole thing is a process and you just start
wherever it happens to come out. And then it keeps coming out dayafter-day as you're sitting in your writing practice. And then you go
back at a certain point with a different state of mind, with an editing
state of mind. And you start finding where the energy is in the
language. And then you throw everything else away that's not those
parts that are marked with energy.
And then from there, you start building a piece. And it's actually the
writing that does the writing. The writing puts together the piece.
The writing tells you, if you listen, "Oh, I don't need to come last. I
need to come first." Like, "Oh! Really? Well, let's see." And then it
either works or it doesn't. But usually it does if the language is
saying so. And that's completely how I -- I never know what the
piece is until it's the piece. I actually am the last to find out.

JM:

That sounds very different to me than other Buddhists' approaches,
which I think sometimes put the emphasis on first word, best word.
As if that extemporaneous outpouring is somehow purer.

�Gail Sher-James Maynard
Page 18

GS:

Yeah, no. No. I totally disagree with that. In fact, I would go so far
as to say that, unless it's crafted, it's not writing. Because who
wants to read that kind of junk that just comes out? It's just junk that
comes out.

JM:

My last question. I think we've been talking about this a couple of
different ways, but I'll end with this. It's another line of yours that I
really am quite fond of. You've written that poetry is dangerous.
Do you want to say anything at the end here about the dangers of
poetry for hapless readers like myself?

GS:

Well, I don't remember saying that. (I'm still back on the last
thought, actually.) This idea of if it's not crafted it's not writing.
The craft part of it is what identifies the voice. And so when I'm
crafting, I don't even know when I first start what voice this poem is
going to assume. And then as I'm crafting, the voice identifies itself,
and then it takes over. And so then it tells you what's allowable to
be in this piece and what isn't, and what's going to be first and last,
and so forth.
So the only danger would be forgetting to let the poem write itself.
Then you could fall into the trap of thinking that you know what the
poem is. And as soon as you do that, you fall into your mind. And
regular mind is not as powerful as wisdom mind. This is my beef
with academics.

�Gail Sher-James Maynard
Page 19

JM:

Get in line.

GS:

Yeah, I'm sure. What's most important to know can't be known with
the mind. And so it's all just chatter, really. So that's why I feel my
poetry is so important, because I'm using language to get beyond
language, which is where all the important stuff is.

JM:

The way I've interpreted that remark of yours, to go back to this
notion of Wisdom Mind, and I think it's in Reading Gail Sher, you
say, "Poetry is dangerous, after all.” It's our vulnerability before
language.

GS:

Yes, exactly.

JM:

Language has the capacity to change us, or to become a
transformative experience. It isn't premeditated; it can't be
controlled.

GS:

It's raw, and it's really like being naked. And so that is vulnerable.

JM:

Well, Gail, thank you very much. This has been an absolute
pleasure to speak with you today. And I can't thank you enough for
your time and your generosity.

GS:

Well, thank you. It's been my pleasure, too.

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                    <text>From another point of view
the woman seems to be resting

•Gail Sher

�Trike • San Francisco •1982

�From another point of vie\N
the \Noman seems to be resting

�Naive or feelings of isolation
and at the same time naive.
The same woman only a feeling
of sun now arrested on the floor
near her chair. Rocking and
making various gestures in
concentrated posture.
From another point of view the
woman seems to be resting.
Perhaps this resting is what brings
the fields into play. Figures appear.
The sky and the woman each
unsurrounded. The sound (of no
concern to anyone else) into
which she feels drawn suddenly.
This scene gives the impression
of fields. Separated from fields
by a porch.

�Settles in watchful
gesture.
Gradual ability. Settles
in place for reading and
life of reading as
insisted internal thing.
Speaks about it softly.
Volition as a kind of
thought. Attributes of
body (sun) and muscles
of body. (Also light in
marked relationship.)
Somewhat confused sense or
some boastfulness coupled
with something else.

�Time and also clouds.
Texture of clouds
and so forth in a
continuous line or
pattern.
Landscape and trees.
(Haze of trees.)
Shoulders arms or
occasional repetitive
thought.

�Now reads. Imagines
herself in the dark
room.
Something recognized
as dark. Shouts for
the little girl.
Presses forward to
some extent.

�Moments held clean and intact
no\N appears as a \Nail. (Method
and exposure to first thought.)
The expression fixed.
Points of softness
absolutely seen by
someone else.
Seeing heavily or seeing
effects of kno\Nn sedentary
person. (Inclusive of her
in an early period.)
Provides a certain luminosity
of detail. At the same time
balance.

�Suggestions in this vein.
(Objects) existing in
unheard sound. (Both color)
and the boundaries of all
objects hitherto mentioned.
Trees but basically the
house is the same.
Reads with attention on
trees shifts entering into
balanced reading.
Or woman lying reading.
Paraphernalia of mind seen
as objects coming to a
complete rest.

�Also as a child she had
wanted to eat

�Also as a child she had
vvanted to eat.
Without particular motive
(to be) on her ovvn crossing
the street on her ovvn or
going through the door
making an effort to buy
food.

�Always with amount of energy
she could spend with that
person (son) or even possibly
some other people.
Even simply listening. Not
urged to but that that had
already occurred.

�Seen by the other people
(during) the day or sometime
during the course of the
day (the driver) calls out
something.
To be phased by this. To
appear calm but actually
to imagine herself
quarreling.

�Intense expression in
striving for something
(intake) of food
(inheritance) of
something.
Having asked for something
to eat (in) one process
to eat one (particular)
part.

�In bed for example (always)
perpetuating (striving) in
the midst of any room.
Which (she) as a lonely
person appreciated.
Avenues and walking with
such &amp; such emotion (buses)
where they seem needed.

�Reversing her terminology
and tendency to want
something from him. (To)
supply food here. (Not)
to move or feel like moving.
With others like her
in the same mood (hiding)
something received from
her.
Delicate relation to her
(discerned) (quarter) of
mind.

�Children &amp; events of the
day enter her mind. Once
while eating (in) quiet
manner of saying something.
Or being in a hurry to get
somewhere. Arrangement of
food at (moment) of giving
it to her.

�Even the lady's pressure
next to her

�Povverful inner lapse or
undivulged sense. (Also)
him in the capacity of
boy.
Pictures of him. Related
in vvay of terrific scene
(bed) or vvarm vvith hand in
book of him.
Through caring charged tone.
Age &amp; body as vvell as
also this caring.
Days later in place of
children (to) see in others
the possibility of her
body.

�Receptive position requiring
this blessing. Short breaths
of sun (minerals) in lap of
her.
Always eats (sings) walks
near river humming &amp; singing.

�Focused on point of
milling crovvd (assembly)
of persons Cvvindovvs) doors
&amp; many people in them
looking avvay.
(Conversation) of vvoman
in curious posture.
COne) face (eventual)
eloquence of her.
Which moves in her. This
abstraction Cvvhich) this
pain vvas.

�Even the lady's pressure
next to her.
(Roughness) of feet also
some cleaning of the room.
Slender girl or (old)
purpose of united her.

�With spread of her (sings)
probing also words.
Waits for bus. Borrows man's
capacity (what) lay behind
in pastime of several minutes.

�Quantities of people among
them (visualized) poised
person (alert) posture of
gratitude.
Or in tovvards her. To utter
it (to) please refurbish
life compelling in this
respect.
Kneels before him (hovv) he
felt alone. Fragrance of
vvood (nails) appealing to
her.

�Travels in sphere of white
or unhappy face . (Ignites)
death response (her) in
group of waking men.
Defining it Cor) reads about
rapture to break this
pattern.
To be awake like this if
not disappointment to be
aware of them redeeming
themselves.

�Perhaps there is no
content paint or sun

�Perhaps there is no content
paint or sun. Wood or light.
1 ) Makes loving motion as of
kissed one 2) Achieves
resistance on a black surface .

�Private inner weight. Conceives
reality of strokes placed on the
paper carefully. Somewhat
revised circumstance (temper) of
hand.

�(Will) mesh in with only
one passively assembled
tone. 1 ) Elements of brown
(tree) (justifiable) pitch
2) As a novelty or given
content in the dress of a
woman.

�Concentrates on pattern vvith
(repetitious) conception of
her eating.
Conception of her addressing
someone. Percentage of vvords
(invvard breathed vvords) along
these lines.
Joined by points though
propelled in free-floating
something (vvhich is) hovv
color vvorks.

�As within sleep something
including him sleeping in
the other room. Also the
woman on the bed. Easily
takes suggestion from the
girl writing. 1 ) Whether
from frightening circumstance
2) Short pause imposed from
without 3) Repeats this
constantly.

�Completes act of eating
(alone) tired &amp; depressed
before eating. 1 ) Only
certain portions of this
2) This and religion
(certain) rosaries.

�A wedge or sound no one
notices. Like a lot of
red (in restful building)
or drives up very
solemn.
Which turns into eating
or ability of someone
with talent.

��© copyright by
Gail Sher 1982
Painting © copyright
by Patty Arnold 1982
Published by Trike
277 23rd Avenue
San Francisco.
California 941 21
ISBN 0-917588-09-6
First edition of 400 copies
Book design by Patty Arnold

��</text>
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                    <text>�THE BUFFALO PHYSICIAN
AND BIOMEDICAL SCIENTIST

Volume 26. '\umhcr I
DIRECTOR OF PUBLICATIONS

Nancy Tobm
EDITOR

Nanette Trd::1l PI kolhg, R..
ART DIRECTOR

Alan

J

k g1er

ASSOCIATE ART DIRECTOR
~con Robert f rit ker
STATE UNIVERSITY OF NEW
YORK AT BUFFALO SCHOOL
OF MEDICINE AND
BIOMEDICAL SCIENCES

Dr john "'Jugl";;on, 'vice t'&lt;r"de·" or
( hmcal \ffa1rs Dean
EDITORIAL BOARD

Dr
Dr
Dr
Dr
Dr
~lr

Dr
Dr
Dr

john A R.• hen Chs ma.,
liar &gt;l&lt;:l Brodv
(,Jcn (Jresham
'\cdr 1 Ha7nson
james Ka~skt
Harok L t
( har cs Pag~nelli
Antui· cttc Pflc·s
L~· her Rohmson
Thomas RPsenthal

Dr
Dr 'iakda
Dr
Dr
Dr
:'&gt;lr
Dr

Surr~r:

Smgerman
Stephen 'ipaulding
'\elson Tc rr
I dward \\"c-uke
jerome )ates

UlLrlO:l

TEACHING HOSPITALS AND
LIAISONS

Ibtana \' ·\ \h:di ... a. Center
Buffak• C.cner.&gt;l Ho,pllal
\lidwel Shaw
Buffatc&gt; \'A ~edicat Ccnte•
( h&gt;ldrcn's lie spital of C:.. '·•lo
K.:rrn Dryja-Swit'r\hl
tnc Ccuntv ~Icc! .cal (enter
.\fwv ,\'orthrrn
\lercy HC'pitJI
\Iillard fillmore llosp11als

Dear Alumni and Supporters of the UBMedical School:

P

rogrammatJc mitt. a~ivcs often r~quirc an extended._Iead time before thetr values ~an be
recognized and their opportumucs brought to frunwn Such IS the situation with the
medical school's development of a centralized mformation system and computer
assisted education &lt;CAl). In the early 1980s, the school embarked on projects
designed to meet ib operatwnalwmputer requirements and to become a leader m CAl.
L ndcr the leadership of Dr Alan Reynard and Dr. john Loonsk, the gains hoped for have
been rcahzed UB represents one of only a few medical schools that offers a required course
m med1cal computmg to ib students and requires medical computer literacy for graduation. [hanks to Alan's and John's leadership we were prepared to computerize all medical
student and resident credcntialing information within 18 months of implementation of
New York State's new 405 Code requirements; LB IS no\\ considered
a model for others to emulate. And we arc considered leaders at the
forefront of CAl.
I he foregoing developments and successes set the stage for even
more exciting opportumues in tht commg years. During 1990 and
the early part of 1991, the Graduate I:ducatton Consortium conducted a wnsultant study rcgardmg destrcd future directions for the
school and the teaching hospitals. That report, conducted by a
consultant staff from Coopers and Lybrand was completed and
accepted by the Consortium in 1991. Soon after its acceptance,
representatives of the Digital lqUipment Corporation learned of our progress and
expressed an mtercst Ill using the Consortium as a model for developmg a truly
community-wdc medical-educatton-health care communicatiOn system. Under Dr
Thomas Riemenschneider's leadership, a planning program involvmg consortia! member~. D1g1tal, IBM. NY" EX and Siemens is now in place, and there is every reason to be
opttm1stiL that UB and its consortia! members will become acttve participants in an
adventure that can serve to move our efforts forward and to showcase Buffalo as a leader
m these important areas It should enhance the quality of medical education and health
care for years to come Both the Physician and I will keep you abreast of future
dewlopmenls.
'&gt;mcercly,

~
(•

0J

~ 1"john i'.aughton, M.D .

Vice Pres1drnr for Clinical Affairs
Dean, School of Medicine and Biomedical Sciences

I-rani&lt; Sava
Roswelll'a; k (anccr lnstitutt:
juJ!Ih RICe
"'''""of ( harit) llosptc 1l
DrnniS \fcC arthv
© I he ~tAte L ,.- ver,llv ol "Jew YJr'&lt; "l
Buffalo
rhc Hu((.. :o Phvs.c &lt;liWild BiomrdtC.II ~(ICII·
liSt ts '?Ubltshcd quarterly hv t~c ''""
L mver&gt;II\ cf "'ew Ycrk ll Bt:!' 1lo 'ic' c PI
of Mcd ;ctnc and Biomedic~: ~cic,ces and
the Office &gt;I Puhhca•tn,s. It is sent 'rce of
c'1Jrgl' tt" odumni, fac11 i 1v ... tuclcnts. rcsl·
dePts "nl! !nerds fhc st~lf reserves ;.he
rag; to edn 4lll c&gt;pv 2.:-:d ~ubmiss..:;'l;:•;; J.c
ccpted for ~L.~Iication

Address quest .c·ns. {.,.)r;:T"' 1.cnts dnd sub,,-; 'i~lons to: l'ditl r. The Bu([ulo Phv&lt;i.·can
cmd Bilnnedical ')dtnt;st ...,t~uc l mver~;~v
ol 'Jew Yo:k at Buffalo l nt\'crs··v •·ubh
cat Lens, I ~t (rAts Hall BuffJio ...... wYcrk

14loO
Send addrc" chan~c' t&lt;&gt;c rl1r lluJ]al·, Phy
sloan antl Bwrm:dica! '\ocntisl. l tf. C P~
Ad&lt;!. lion, H 15 Main S~rcct Buffalo. ~ew
York 14!1 t

Cover Illustration by Jay Lincoln

Dear Fellow Alumni:

D

on't le.t the wmtcr doldrums get you down 1 The Alumm. Assouation is offering some
warmmg and cheerful events.
On january 18, 1992. we held the Senior Reception for our future alums. As in years
past, It was greatly appreciated and enjoyed by the scmors alums and faculty
The Chairpersons for the Reunion Classes arc busy making plans for an exctttng
n:umon weekend in Buffalo on April 25. You will be heanng more from them during the
commg weeks.
\Ve have a lot to be proud of in our medtcal school and our strong
and active Alumni Association This is due to the strong support from
vou, our alums'
' If you have any questwns, please feel free to call me at my office.
':imcerely

~~· ~
Nedra]. Harrison, .\1.D., '77

�WIN T ER 1992

VOL. 26 , No . 1
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........... . .. .. .......... . . . .. . .. . .... .. . . ..... . .. . ..... . . .. ...... . ......... . .. . .. . ...... . ...

Research
Hospital News
Further Notes on 11 The Other Classroom" • The School
of Medicine and Biomedical Sciences' dean,John
Naughton, M.D. , looks at the advancement of the
medical school's teaching hospital relationships.

Journey to the Top of the M.D. Ladder • For women,
UB researchers have developed a "smart
pill" that knows where to go and what to
do when it gets there. Page 3.

according to some, it's a longer climb.

ASpoonful of Humor • A West Coast pediatrician
and University at Buffalo graduate prescribes it
for his patients and peers alike.

Medical School
People
Alumni
Classnotes
The neurologic problems of musicians and
singers ore the subject of a lecture by
neurologist Alan Lockwood, M.D. Page 2.

Dean Naughton's further notes on
"The Other Classroom." Page 6.

* Millard Fillmore Hospitals opens its new podiatry clinic. Page 4.

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Success of new biotech
drugs depends on
prescreening patients

Lecture focuses on problems
of musicians and singers
eurologic problems that tend
to strike singers and musicians
were the main topics of an
evening of medicine and music
held in early December at UB's
Baird Recital Hall.
The combination lecture and recital
featured performances of various instruments, followed by a brief presentation on the injuries that typically are
found in matching performers.
University at Buffalo neurologist Alan
Lockwood, M.D., internationally known
for his research and clinical treatment
of musicians and vocalists who incur
neurologic problems as work-related
disorders, discussed clinical case studies. Lockwood is a professor of neurology and nuclear medicine.
Edward]. Fine, M.D., clinical associate professor of neurology, explained
the roles of electromyography and
electroneurography in the diagnosis of
music-related neurologic problems.
An estimated one-third of professional
singers and musicians likely will expe-

8

BUFFALO

PHYSICIAN

rience some neurologic problem related
to their work at some point during their
careers. While a large percentage of
these involve peripheral nerves, others
may be traced to the central nervous
system.
Although surgery is indicated in a
small percentage of the cases, a greater
number can be treated effectively with
physical or occupational therapy.
"Although most people are aware of
work-related disorders that can occur in
various occupational groups, those
among musicians and singers are not as
well understood in the general population," Lockwood said.
UB faculty who performed included
Stephen Manes, chair of the department
of music, piano; Ronald Richards, a lecturer in the department of music, oboe;
Deborah Chung, professor of mechanical and aerospace engineering and
Niagara Mohawk Chair of Materials Research, piano and voice, and graduate
student Patti Cudd, percussion.
The event was co-sponsored by the
Buffalo Chapter of Sigma Xi and the UB
departments of music and neurology.+
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he success of expensive new
biotech drugs that are nearing
government approval will depend
in large part on identifying the
patients most likely to benefit
from them, according to a UB
professor of pharmacy.
Speaking at the annual meeting of the
American Association of Pharmaceutical Scientists in November, jerome ].
Schentag, who is also director of the
Clinical Pharmacokinetics Laboratory
at Millard Fillmore Hospital, referred to
E5 and Centoxin, both costly new treatments for the often fatal gram negative
sepsis infection, as cases in point.
"The challenge with these new products is going to be proving that they
work and communicating to physicians
~hich patients will clearly benefit from
the treatment," he said. "If given indiscriminately, the cost to the health care
system for the sepsis drug alone would
approach $1 billion. When you're talking about $4,000 to $5,000 for a single
dose, you need to pick your patients
carefully."
Each year, gram negative sepsis infection strikes 500,000 patients, most of
whom are
already

SPINA

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�···· · · ·· ··· ····· · · · ····· ·· ······· ···· · · ··· · · · · · · · ···· ·· ·· ·· · ·· · · · ··· · · · · ··· ·· ·· ·· ·· · · · · · · · ·
·~

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ill with cancer, heart or liver disease or
who have just had major surgery.
New treatments for sepsis block the
action of endotoxin, the product of bacteria that causes most of the
injury. In some cass, the new
biotech treatment has completely cured patients. But
other patients have seen little
or no improvement following
treatment.
According to Schentag, this
discrepancy in how the new
drug affects patients is what
makes vigorous prescreening
of patients so necessary.
+
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geting drugs in the GI tract involve
intubation. In contrast, the new targeted capsule is swallowed and its
progress monitored by use of a tracking

··'

GOLDBAUM

Smart pHI" knows
where to go after
it's swallowed
11

"smart capsule" that
allows researchers to
precisely direct nearly
any medication to a
specific place in the
gastrointestinal tract has been
developed by scientists and engineers at
the State University of New York at Buffalo and Millard Fillmore Hospitals.
Described at a meeting of the American Association of Pharmaceutical Scientists in Washington, D.C. , the ingestible capsule and its microelectronic technology have important implications for
treating patients who require repeated
delivery of a drug, such as insulin, to a
small area of the intestine where it can be
absorbed.
David T. D'Andrea, director of the
Engineering and Devices Laboratory of
Millard Fillmore Hospitals, is co-investigator on the project.
Schentag, who also directs Millard's
Clinical Pharmacokinetics Laboratory,
explained that current methods of tar-

BUFFALO

PHYSICIAN

device worn as part of a vest. The vest
houses a computer monitor about the
size of a Walkman.
As the capsule, which contains a tiny
radiotransmitter, passes through the GI
tract, it sends out a continuous radio
signal as the computer monitor system
computes the position of the capsule
and triggers release of the drug when it
gets to a predetermined spot in the intestinal tract.
Schentag noted that the technology
would allow for the intact delivery of
drugs such as insulin and some of the
new biotech drugs, which are large proteins that are usually degraded by the
acid in the stomach or the enzymes in
the intestine.
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UB surgeon performs
world's first splenectomy
by laparoscopy at BGH

..

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surgical procedure
known as a laparoscopic
splenectomy was performed for the first time
on October 10 when a
University at Buffalo
surgeon removed the spleen of a
24-year-old woman at Buffalo
General Hospital.
Scott A. Tulman, M.D., clinical assistant professor of surgery, says the clinically experimental technique was made possible by the development of new
tools for advanced laparoscopic
surgery by U.S. Surgical Co.
According to Tulman, the
woman was suffering from hereditary spherocytosis, a congenital condition that causes severe,
hemolytic anemia. The woman's
gallbladder was also removed
during the surgery, which lasted
two and one-half hours.
"Although the condition is rarely fatal,
it is extremely debilitating and requires
numerous blood transfusions or removal
of the spleen, depending upon the severity of the condition in the individual
patient," Tulman said.
During the laparascopic splenectomy,
small, half-inch punctures were made in
the patient's abdomen and the recently
developed
laparoscopic
instruments
were
inserted.
The surgery was
performed
with
no
complications.
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MDiard Fillmore
Hospitals podiatry
clinic opens at Gates
illard Fillmore Hospitals now offers
specialized
podiatric care in its
newly opened Foot
Clinic in its Gates
Circle facility.
The clinic offers routine
podiatric services as well as preventive foot care for patients
with diabetes and peripheral
vascular disease, according to
David M. Davidson, D.P.M.,
chief of the podiatry section at
Millard Fillmore Hospitals.
"In addition to meeting the
community's growing need for
podiatric services, the Foot
Clinic helps contribute to the
comprehensive, quality health
care services at Millard Fillmore
Hospitals," Davidson said.
The Foot Clinic is staffed by
American Board of Podiatric Surgery
board certified podiatrists from the
hospital's medical staff.
+

PET imaging center to
bolster research and
enhance patient care
he opening of the new Positron
Emission Tomography (PET) imaging facility at the Buffalo VA
Medical Center marks completion
of the first phase of a cooperative
effort between the hospital and
the University at Buffalo to bolster medical research and patient care in Western
ew York.
The center will be completed in 1993
with the opening of a cyclotron facility

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that will manufacture radionuclides for
use with the scanner. Work on the
cyclotron facility, to be located in renovated space on UB's South Campus, began last summer. Until it is completed,
materials used in scanning at the hospital will be provided by outside sources.
Once the cyclotron is operating, underground pneumatic tubes connecting
the hospital and Parker Hall will be used
to transport radionuclides produced by
the cyclotron facility for use with the
PET scanner.
Because of its unique ability to visualize and quantify complex physiological
processes occurring in the human body,
PET imaging has potential for important
advances in the understanding and treatment of major ailments, including heart
disease, stroke, cancer, epilepsy and

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Alzheimer's disease.
The first one in Western New
York, the PET scanner at the
Buffalo VA Medical Center is
one of only four in the state and
one of two approved for use
with patient care.
While there are several dozen
PET imaging centers in the U.S.,
the UB-VA center will have
clinical and research capabilities shared by only a few PET
imaging centers located at other
major research institutions, according to john Naughton,
M.D., UB vice president for
clinical affairs and dean of the
medical school.
"This project will put the UB
medical school at the very edge
of a new frontier of diagnostic
medicine," aughton said.
While located at the Buffalo
VA Medical Center, the PET
scanner will be available to veterans and other patients
throughout Western New York
through a shared services agreement between the University at Buffalo
and and VA Medical Center.
The center is being funded through a
$3.4 million federal grant from the Department of Veterans Affairs, with the
balance of the $12 million cost of the
center provided by UB, state grant support and private support. Funding includes a $1 million grant from the james
H. Cummings Foundation in the form of
a contribution to the
University
at Buffalo
Fotmdation's
"Pathways
to Greatness Campaign." +
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�First Stereotadic Radiation
Therapy performed at
Roswell Park Institute

most effective
for the treatment of target areas up
to three cen56-year-old Tonawanda, New
timeters in
York, man became the first pamaximum ditient in Western New York to
ameter. The
be treated with Stereotactic Raprocedure
diation Therapy of the Brain
gives access to
(SRTB) for a recurrent malig- deep-seated lesions which were formerly
nant brain tumor.
inoperable or could be reached only by
The procedure, which uses sophisti- extensive surgery, according to West.
cated digitized computer targeting, was
"The precise, pinpoint accuracy of this
performed by Kyu H. Shin, professor and procedure enables us to deliver a high
chairman of the department of radiation dose of radiation in single or multiple
medicine at UB's School of Medicine and doses to a well-defined, small intracraBiomedical Sciences and head of the de- nial area without delivering significant
partment of radiation medicine at Roswell radiation to adjacent normal tissue," Shin
and Charles R. West, M.D., research as- said.
sociate professor of neurosurgery at UB
SRTB requires a high degree of posiand head of the department of tional accuracy. CAT, MRI scans or
neurosurgery at Roswell. Roswell Park angiographic studies are performed to
Cancer Institute is one of 28 National determine the center and dimensions of
Cancer Institute-designated Comprehen- the target and compute the isodose dissive Cancer Centers nationwide.
tribution. Treatment is first simulated
The patient, who was diagnosed with a to ensure accuracy. The procedure,
highly malignant, very advanced which usually takes about one hour, is
glioblastoma, had already undergone then performed using the photon beam
surgery and conventional radiation which of the high energy linear accelerator.
had failed, according to Shin. The suc"We couldn't be more pleased with
cess of the new procedure, Shin said, will this first procedure," said West. "The
not be known for several months until a dose of radiation was delivered to the
repeat CAT scan is performed. "It takes tumor exactly as the computer had caltime to know," Shin explained. "The culated. The future for this therapy is
mass is still there and there is no way of exciting and promising for patients. " +
knowing whether it's dead or alive until
we see no tumor on subsequent CAT
scans. With highly malignant tumors ,
the response is somewhat quicker. "
The noninvasive procedure, which can
be performed on an outpatient basis, has
been used in other centers to treat a
variety of benign and malignant lesions,
such as arterio-venous malformation ,
acoustic neuroma , pituitary adenoma,
craniopharyngioma, single metastatic
lesions and malignant brain tumors. It is

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BGH and ECMC announce
plans for computer services
in a new ioint venture
he Buffalo General Hospital and
Erie County Medical Center have
announced plans to join forces to
develop and install a fully integrated computerized information
system at the medical center.
Under terms of the collaborative agreement , Buffalo General will provide
ECMC with a variety of services, including the computer capability required to
process ECMC data volumes and operational statistics; installation/systems development; staffing and services; training, and ongoing operational support as
well as hardware, software, database and
communications support.
The ECMC system will be implemented in phases with the first "go live"
date tentatively scheduled for early january. The final phase of the project is
scheduled to be implemented in january
1994.
Under the agreement, ECMC admissions, registration and patient accounting information will be stored in separate data banks at Buffalo General and
transmitted to ECMC via a microwave
connection. Hospital officials noted that
it will be a controlled process to ensure
total patient confidentiality between the
two institutions.
+

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�The following is a continuation of
Dean John Naughton's paper, "The
Other Classroom," published in the
Late Winter 1988-89 issue of
Buffalo Physician and Biomedical Scientist •

Copies of the earlier paper are
available from the medical school.

PHOTOS
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uring the Fall of 1988 a major retreat was held at the Buffalo General Hospital focused in
its continuing relationships with the medical school. A number of perspectives were
presented and positive communications developed considering existing and future relationships. My presentation concerning the development of cooperative arrangements
through the formation of consortia, entitled "The Other Classroom," was printed in The
Buffalo Physician and Biomedical Scientist. 1 A manuscript detailing the role ofUB's medical
school in regional economic development is being published this winter in, Metropolitan
Universities .2 This paper will expand on the earlier publication and present some more
contemporary views abou t how the University at Biffalo and its affiliated institutions
strengthened their relationships through cooperative planning and programmatic sharing.

[urrent [onsortial ~trategies
GRRDURTE HEDICRL DEHTRL EDUCRTIOH
COHSORTIUH OF BUFFRLO
The medical school and its teaching
hospitals entered into their first consortium in 1983 to respond in an efficient
and cohesive manner to the new guidelines promulgated by the Liaison Committee in Graduate Medical EducationJ
A major leadership role was provided by
Michael oe, M.D., senior vice president for professional affairs and medical
director at Buffalo General Hospital; he
has been an active leader throughout its
development and evolution. This organization , the Graduate Medical Dental
Education Consortium of Buffalo
(GMDECB), governs all residency training programs in Western ew York. The
organization's institutional members
include the affiliated teaching hospitals,
the schools of medicine and biomedical
sciences and dental medicine, all residency training program directors and
one resident representative from each
program. The work is conducted through
a series of committees, i.e., Administrative, Program Directors, Residents and
Coordinating. Over the past eight years,
the GMDECB has been developed as an
alternative model for other medical
schools and their affiliated institutions
to consider when dealing with the need
to change their approaches to managing
graduate medical education (GME). The
GMDECB is now positioned to deal institutionally with the many issues that

0

BUFFALO

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ono~~ue.
m.~., t~e ~rfmf mrector for

[ontinuin~ menical fnucation.

~rouinen t~e leaners~i~ for t~is
im~ortant innouation.
AND

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face the medical education and health
delivery systems. For example,
GMDECB responded rapidly to the new
requirements imposed by ew York State
imposing the credentialing of medical
students and residents. The program
directors worked cooperatively to develop the required programs and reporting mechanisms, and with support made
available from the Information Service
system under the leadership of Alan Reynard, Ph.D. , a computerized reporting
system was operational systemwide on
July 1, 1990. The total time between the
announcement of the new requirements
and implementation was about 18
months.
Institutionally, GMDECB has moved
forward to change the method of orienting new residents. The usual one- to
three-day hospital orientation was replaced by a comprehensive week-long
curriculum. Its course contents include
the usual personnel issues; completion
of the required history and physical examination at a single site; training and
certification in advanced cardiac life support; learning and evaluation of bedside
teaching skills and lectures and small
group sessions dealing with medicolegal,
record keeping and ethics.
Glenda Donoghue, M.D. , theAPFME
Director for Continuing Medical Education, provided the leadership for this
important innovation. 4 A total of 125
individuals representing specialties in
medicine, law, nursing, medical record
librarians and hospital administration
participate as faculty for this unique and

SCIENTIST

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�important function.
The GMDECB responded to the initiatives of the YS Council on GMP·6 ·7 •8
by committing to a ratio of 50 percent
distribution of resident positions to primary care (family medicine, internal
medicine and pediatrics) by 1994; recruiting and retaining representation
from
minority
and
socially
underrepresented representatives of at
least 11 percent of the total pool , and
evaluating and studying the strengths
and weaknesses ofconsortia! governance.
The Council's subcommittee in Consortia evaluated GMDECB's progress in 1989
and 1991 and reported to the Council
that we were meeting its definition and
criteria for an operational consortia.
The GMDECB's most recent accomplishment was the pooling of resident
salaries into a single organization. This
has enabled the teaching hospitals to pay
all residents across the system one equitable salary and common fringe benefit

BUFFALO

PHYSICIAN

rates. The residents have a consortialwide annual dinner dance, and each
receives a UB certificate upon graduation with all member institutions listed
on it.
These
changes together
with other attempts
at standardization
of the education
programs are serving to confirm that
GMDECB is indeed
the "institution of
record" for graduate medical education in Buffalo and
Western ewYork.

vices was formed in 1987. This organization, the Western New York Health
Sciences Consortium (W YHSC), has a
membership similar to thatof GMDECB.

UJESTERH HEUJ YORK
HEHLTH SCIENCES COHSORTIUH

In addition there are those representatives from the business community and
each board chairman of an affiliated hospital and the president ofUB. This organization is incorporated and is not a
membership body as is GMDECB.

A second consortium designed to
emphasize the need to cooperate and to
enhance the quality of health care ser-

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Above, Millard Fillmore

i'-11!11111•

Suburban Hospital's
newborn nursery, now
under the diredion of
Children's Hospital's
Division of Neonatalogy. Left, Buffalo
General Hospital's
designated Heart
Transplant Center.

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The formation ofWNYHSC was more
difficult than was that of GMDECB because its focus affected more constituents. It originated at the institutional
levels and was perceived as a "top-down"
organization. The rapidity with which it
formed and the breadth of the agenda
caused a great deal of consternation for
full-time and voluntary faculty alike.
The approach taken to accomplish its

--------------------------------~-

constituents was high, and too little preparatory work was performed to decrease
existing tensions and to facilitate the
necessary work and leadership.
evertheless, a number of significant
and positive outcomes can be ascribed to
W YHSC during the course of its short
history. Among these were: (1) awarding of a Bone Marrow Transplant Center
to Roswell Park Cancer Institute (RPCI);
(2) completion of a clinical affiliation
agreement and faculty contract between
UB and the RPCI; (3) designation ofBGH
as the Heart-Lung Transplant Center, (4)
the formation of a single Division of
Neonatology in Pediatrics to coordinate
neonatal care at Children's Hospital of
Buffalo (CHOB) , BGH, Sisters Hospital
(SH) and Millard Fillmore Hospitals
(MFH); (5) rationalization of an integrated psychiatry program; (6) securing
of a shared agreement between the Buffalo VAMC and UB for a center in Positron
Emission Tomography (PET)imaging,

goals was to use task forces usually
chaired by a UB clinical department chairman or a department's division chief.
The composition of each task force included full-time and volunteer faculty,
representatives of hospitals, the school
and the business community. Most task
forces proceeded to achieve their intended outcomes. Three others had more
difficulty because tension among the
Left, the VA Medical
Center's new PET scanner
will provide enhanced
medical imaging for
Western New York
through a shared
agreement between
VAMC and the University

...____ _ --~-......-II!Ci::!!C;,;_:E::::::...::::::__ _ _~--_. at BuHalo.

Above, Erie County Medical Center's designated Trauma-Burn Center.

«&lt;)

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�and (7) the designation of the regional
Trauma-Burn Center at Erie County
Medical Center (ECMC).

lion dollars, and the scales of economy
for BGH will be significant.
UB's Health Sciences Library belongs
to a regional health library consortium
and services the Western New York region. The school has a major computerassisted educational capacity. lt is envisioned that these systems will be added
to the other networking activities, thus
bringing educational and informational
services directly to the bedside and clinical settings in the years ahead. There is
no doubt that Buffalo's willingness to
enter into more and more cooperative
planning has served to move the school
and the community into a leadership
role in these areas.

IHFOJUtJlnOH HET\UORKIHG
ll of the above activities serve to
network the institutions around
the mutual purposes which each
shares. One of the beneficial byproducts has been the ability to
develop a computer network
which links the medical school
with each department and each
teaching hospital. This network
has matured to the point that it is attracting national interest as a model which
can be emulated in other regions of the
country. Thomas Riemenschneider,
M.D., associate vice president and associate dean for clinical affairs, is providing valuable and constructive leadership in this area. In 1990, theW YHSC
received a consultant's report from Coopers and Lybrand which will serve as a
blueprint to future planning and implementation of this network. Several commercial firms have indicated their interest in pursuing a partnership in moving
this system forward since no comparable program with this potential exists
in any other community in the United
States at the present time. Since UB is
also developing unique strategies for
interactive computerized education under the leadershipof]ohn Loonsk, M.D.,
has a networked community-wide system in place and has an outstanding
Health Sciences Library which serves
medical students, residents, full-time and
volunteer faculty and each hospital in
Western ew York, the consortium is in
a unique position to provide a model of
delivery information to a broad range of
constituencies in the region.
Another example of cooperative planning is that Buffalo General Hospital and
Erie County Medical Center (ECMC)
are working collaboratively to establish
a single computer mainframe for patient
billing and medical record keeping. In
this model the mainframe will be owned
and operated by BGH and services will
be purchased by ECMC. The potential
savings to ECMC will total several mil-

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[urrent ~tatus

~iemensc~neiner. m.~ .. associ-

ate uice presinent ann associate
nean for clinical affairs. is
prouining ualuaMe ann construehue leaners~ip to neuelop a
computer networ~ lin~ing t~e
menical sc~ool wit~ its teac~ing
~ospitals.
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While it is apparent that UB and its
affiliated hospitals have taken steps to
enhance cooperation and sharing, more
needs to be accomplished to ensure quality medical education and patient care at
a time when the health care system is
undergoing rapid, sometimes unpredictable change. Since many constituencies
must be represented in the decisionmaking process, yet some decisions must
be made expediently, UB's former president, Steven B. Sample, recommended
that the WNYHSC model be strengthened through a mechanism of increased
centralized control with UB assuming a
more authoritative role. This plan, the
University ofBuffalo Health System, Inc.
(UBHS), received considerable public
discussion within UB and the State University of New York system, the New
York State Department of Health and at
each involved Buffalo institution. While
considerable support for a strengthened
consortia! model exists, it was clear that
progressing toward a cooperative model
in which each member enjoys a partnership role is preferred. To that end, UB's
president, William Greiner, has offered
an alternative plan, now identified as the
University at Buffalo Affiliated Hospital,
lnc. (UBAH). The affiliated hospital
CEOs and the medical school leadership
are engaged in developing a plan that

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can be acceptable to SU Y, UB, hospital
boards and the full-time and volunteer
faculty. The tenets of common agreement and need are being developed; by
late 1991 the process of muerging the
two consortia into a single organization
could begin. It appears that the medical
education and health care communities
which serve to form UB's other classroom, a "medical school without walls,"
are committed to increasing cooperative
activity in an era of declining resources
and changing patterns of rendering medical education and health care. If these
institutions and constituencies continue
on these vectors, then UB and its affiliates could provide important, necessary
leadership for other sectors in New York
State and the nation.

[ondusions
n important lesson learned from the various consortial experiences is that meeting the challenges that face our institutions
requires the work of multiple constituencies coordinated by a
responsible leadership group. The medical school and UB have
an important, but not singular role in that process. Given the
history of the medical school and its teaching hospitals, UB must
be committed to achieving its major academic goals in an
environment committed to taking advantage of diversity and
through a philosophy of inclusion rather than exclusion. The
GMDECB has served to demonstrate the value of cooperative
management, planning and execution. WNYHSC served to
demonstrate the need for institutional cooperation and sharing.
Although the pressure to render decisions precisely and expeditiously
will continue to occur, it appears that the cooperative, multiconstituent
model will work more effectively than a strongly centralized, "top-down"
organization.

1. Naughton,]. , The Other Classroom, The
Buffalo Physician and Biomedical Scientist,
Late Winter 1988-89.
2. Naughton, ]., "The Impact on Regional
Health Care By A Medical School And Its
Affiliated Teaching Institutions: A Potential Model For Other Academic Health Center," for publication in Metropolitan Universities late 1991.

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3. 1980-81 ACGME Guidelines, The Essentials of Accredited Residencies in Graduate Medical Education , Feb. 24, 1981.
4. Donoghue, G.D., Glieco, . Flint, L.M. ,
Naughton, ]. "A Core Curriculum for Entering Graduate Medicine Education Trainees" to be published in Teaching and Learning in Medicine later this year.
5. Report of the New York State Commission on Graduate Medical Education, Feb.

First Reportofthe Council, Volume I, 1988.
7.
ew York State Council on Graduate
Medical Education, Second Annual Report,

1989.
8.
ew York State Council on Graduate
Medical Education, Third Annual Report,

1990.
9. Pristach , C. , Donoghue, G. , Sarkin, R.,
Wargula, C. , Doerr, R., Opila, D., Stern, M.,
Single, G. , "A Multidisciplinary Program
To Improve The Teaching Skills Of Incoming Housestaff," Academic Medicine, 1991.

1986.
6. Council on Graduate Medical Education

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�The Burn Treatment Center at Erie County Medical Center, one of the significant achievements of the Western New York Health Sciences Consortium.
4. Report of the National Advisory Commission on Health Manpower, Washington, D.C.: Gov Printing Office, 1967.
5. Sickness and in Wealth, ewYork: Basic
Books, 1989.
6.
Caring for the Uninsured and
Underinsured (several articles) , The journal of the American Medical Association,
May 15, 1991 , Vol. 265 , No. 19, (pgs. 2491+
2566).

l. The New York State Council on Graduate Medical Education, First Annual Report, 1988.
2. Chapter on Consortia, ew York State
Graduate Medical Education Councils' Third
Annual Report, 1990 (In Press) .
3. Public Health Policy Forum, American
Journal of Public Health, April 1991 , Vol.
81, o. 4 (pgs. 418-420).

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ECMC's designated Levell Trauma Center serves
the eight county Western New York area.

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By Lois Baker

When top administrators at

the University of Iowa

For women)

Medical School met for a

presentation on a new

security system, the marketing

representative turned to the

group of distinguished profes-

sionals, which included two

longer climb
women, and asked, "Why

don't one of you girls come

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�Mary Ann Bishara, M.D.

medical establishment's upper echelons.
Aschenbrener instead described her treatment throughout her career as a "day-today kind of minor assault," manifested in
this instance by a boorish salesman's offthe cuff comment.
The presence of Aschenbrener, Conley
and a small number of other female physicians in the top ranks of the formerly all
male medical establishment is a sign that
women are breaking through societal barriers which in the past forced those inter-

ne of the "girls" was neuropathologist Carol Aschenbrener,
M.D ., the highest ranking
women in academic medicine in
the U.S. today.
Aschenbrener, executive associate dean at the University of
lowa Medical School, perhaps is
lucky. She has not experienced the overt
discrimination or sexual harassment, such
as Stanford neurosurgeon Francis Conley,
M.D., reported, during her climb into the

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ested in healing the sick to become nurses,
not doctors.
But unlikejoshua fighting the battle of
jerico, their assault on the medical status
quo has not brought the walls of inequity
tumbling down ; it has created only a small
breach, leaving women physicians, after
years of proving themselves accomplished,
and often brilliant, still struggling for equal
opportunity and respect in their profession.
"l am troubled ," Aschenbrener said,

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�"by the persistence of subtle expressions,
from men and women both, that indicate
still an underlying belief that women are
second class, and that yes, they can succeed, but their real place is in the home. I
perceive this societal pressure as being
more intense now, at least in the media ,"
she added, "than I did 20 years ago. "
Statistics certainly do not paint a glowing picture:
• A year ago there were three women
deans in the nation's 127 medical schools.
Today there is none.
• A report published last fall by the American Medical Women's Association and the
Feminist Majority Foundation showed that
today women make up 36 percent of medical school students but hold only 2 percent of the department chairs.
• In 1990, 20 percent of all medical school
faculty were women - only a 7 percent
increase in l3 years.
"At that rate," the report stated, "women
will not reach parity on medical school
faculties until the year 2077. "
Men also outnumber women in the
higher faculty ranks. Statistics compiled
by the Association of American Medical
Colleges show that in 1991 nearly three
times as many men than women were full
professors.
That gap can be attributed in part to
women's later entry into the profession.

But when the Association followed promotion records of full-time faculty first
appointed in 1976, it found that by 1991 ,
more than twice as many men as women
had been appointed full professor.
Inequities follow through medical specialities - women are clustered in the
lowest paying fields ; through wages- the
American Medical Women's Association
reports female physicians receive 62.8
cents for every dollar earned by their male
counterparts; and through medical organizations- the American Medical Association finally put a women on its board in
1989.
By many indications, male and female
physicians in this country are not treated
equally. The medical profession appears
to feature a so-called glass ceiling that
prevents women in substantial numbers
from reaching the top.
How could this situation persist in the
enlightened 1990s?
For Eileen McGrath, the answer is clear.
"I think the only reason for a glass ceiling
in any group would be discrimination,
and I think discrimination exists because
of ignorance." McGrath is executive director of the American Medical Women's
Association. "It is clearly documented
that a glass ceiling exists," she said, "particularly in academic, but in all aspects of
medicine."

Nancy E. Gary, M.D.

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iscrimination against women is
partly deliberate, partly unconscious, she said. "Most of the
injustices we see are probably
the result of unconscious acceptance of values in which one
group is privileged at the expense of another group ,
whether it's race or gender. But the effect
is the same, so it is sort of immaterial. I've
known very few intelligent men who
could defend it logically. "
Frances Conley at Stanford has become the standard bearer for women physicians who are frustrated by their treatment at the hands of male colleagues and
the medical establishment. Conley's oped piece in the San Francisco Chronicle
last june, following her resignation from
Stanford Medical School's neurosurgery
faculty, detailed years of indignities and
sexual harassment, including male colleagues calling her "honey," running their
hands up her leg in the operating room
and commenting on her breasts. Her
public statement shocked the campus
and raised a furor in the national media.
Conley eventually rescinded her resignation, electing to work within the medical school to bring about change. She
continues to press for equal, dignified
treatment for women at Stanford and elsewhere.
''I'm here as a conscience," Conley said.
"To remind people every time they see my
ugly mug that there's some unfinished
business."
Conley thinks wide spread bias against
women exists in many occupations. "Our
society has a mind-set," she said. "We've
been taught ever since we were small
children that women were not quite as
good as men. The thing that is most
depressing to me is the stereotypical response from institutions to women who
make an issue of it. They get rid of them."
As a tenured professor with a wellestablished reputation, Conley can't be
"gotten rid of. " But she admits her future
at Stanford Medical School is not bright.
"Things are relatively hostile," she said.
"What I did is not exactly an acceptable
behavior pattern for women. My department will never forgive me I'm sure."
Olgajonasson has not experienced the
kind of sexual harassment Conley de-

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�scribes, but she believes it happened to
Conley, and says similar things happen to
women in medicine all the time.
jonassonchairs the DepartmentofSurgery at Ohio State University College of
Medicine, one of two women surgery department heads in the U.S., as of july
1991. She has held the position for four
years.
"I think it is just constantly part of daily
living," jonasson said. "I don't believe
women are given the credence that men
get. We tend to be ignored, passed off."
She has dealt with such treatment in
the past by ignoring it, but for young
women physicians today she has other
advice. "In the past I would have said just
swallow it and make do," she said. "I don't
know that that is practical, possible or
reasonable these days. We have to make it
clear we won't put up with these things."
"It is not possible as a woman to go
through medical school without some
discrimination," stated Paula Clayton,
chair of the Department of Psychiatry at
the University of Minnesota Medical
School. Clayton, a specialist in mood
disorders, is the only female currently
heading a department of psychiatry in the
U.S., although the field has been popular
with women for some time.
She describes her own experience with
discrimination as "little things- more in
whether you deserve the same office" but tells about the complaints of a friend,
a top researcher at Yale. "She has had
trouble getting promoted, so there must
be some bias against promoting women."
Not all women physicians agree that
discrimination is a problem in medicine.
Nancy Gary, a nephrologist, is former
dean of Albany Medical School. She left
that position 17 months ago to become
senior medical advisor to the administrator of the federal Health Care Financing
Administration.
Gary said she does not think a maledominated medical establishment prevents women from advancing. She thinks
women are underrepresented in the top
ranks of medicine because they are latecomers to the profession.
"It's a time-related aspect," Gary said.
"Women have only been entering graduateschool in any significant numbers since
the 1970s. Then you have to add three to

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Pat Duffner, M.D.

seven years of training and getting started
in the lower academic ranks. Only now do
you have a significant number of women
reaching the maturity in their profession
to realize such opportunities as chair positions."
If a glass ceiling exists, it is caused by
personal choices, not by institutional discrimination, she feels.
"I think there may be limitations on
opportunities various people can achieve
by virtue of their preparation, their willingness to take risks, their willingness to
go on divergent paths to reach certain
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a very individualized pursuit of a career
that determines whether there is a glass
ceiling."
Clayton agrees that the choices women
make may contribute to their concentration in medicine's lower ranks.
"I think we have to take some responsibility for not getting ourselves promoted, " Clayton said.
"My experience as chairman, and even
before becoming chairman, is you have to
be a researcher to get promoted. I don't
think women are as intense about their
research as they should be. They tend to
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and it's instantly gratifying.
things are good, you are not going to make to identify the unique barriers women face
"The feedback in taking care of people it in academic medicine.
in using the system, and find out how to
is so much quicker than planning a re"You have to be comfortable with your- get leverage from women colleagues and
search project, executing it, writing it up self," Duffner added. "I think if women sympathetic male colleagues."
·and getting it published, that we tend not would just relax to some extent and not
Mentoring is indispensable for women
to do those things," she said.
fight it so hard, and feel comfortable in in medicine, Gary emphasized. "People
Clayton speculated that women also their expertise, things would be better. are identified to move on because they've
had their career shaped by someone in a
may not be advancing as fast as they But that's easier said than done. "
Clayton said that if women want to position to guide them and advise them.
should because they are not as mobile as
men . "There are many women associate advance they have to publish. "And not Then they need the contacts, so when an
deans, but why those women aren't being just books," she emphasized. "It's easier opportunity becomes available, someone
promoted, that's the disturbing question. to write a non-refereed book than to pub- thinks of them as a potential candidate. "
Practical advice notwithstanding, mediSometimes it's tough to get promoted from lish in respected refereed journals. Women
within. You have to be able to move. And also have to protect their time, so they can cine remains a demanding profession. For
women may not be as flexible. I know of do the research necessary to publish, she many reasons the burden seems to be
a woman whose husband
greater for women.
"I think one ought not
told her when they got
to have to be an exceedmarried: 'You can move
once."'
ingly strong person to
On the other hand,
succeed," Aschenbrener
UB's School of Medicine and Biomedical Sciences
women may simply be
said, "but I think someranks 25th among the nation's 147 medical schools
times with women that
more particular about the
in the number of -women in its student body. A study
is the case. There are
jobs they take. Jonassen
conducted by the Association of American Medical
Colleges in 1990 sho-wed that 41.5 percent of UB's
still an awful lot of socisaid she has had several
medical students -were female .
etal factors that are baropportunities to be a canToday the percentage is even higher. This spring
riers to women. They
didate for a deanship, but
73 -women- 4&amp; percent of the class- -will receive
turned them down bestill have to do more
medical degrees from UB. The follo-wing table
cause the offers didn't
work. They still have
tracks female graduates for the past 10 years.
come from the right place.
responsibility for home
and children."
Clayton too said she has
50% ------------------------------------------;---Aschenbrener has
been asked many times,
but isn't interested in bethrived
in a difficult ca40%
;---;---h
;---;---..... 7
coming dean.
reer
by
following
the ad14&lt;-'
"Being a dean is more
vice
of
her
grandfather
- 30%
47
4,~
4~
~ ~
nurturing, and I don't
- "Do whatever your
want to take care of more
task is as well as you can,
20%
people," Clayton said. " !
and everything else will
want to be involved with
fall into place." To that
10%
philosophy she adds
psychiatry and research,
some wisdom of her
or something bigger than
0
1983 1984 1985 1986 1987 1988 1989 1990 1991 1992
dean ."
own: develop strong values, stick to them and
But statistics tell us
that most women in medicine do not have said. "You can't be the token member of reflect on them often.
Despite the difficulties women in medithese options. Many are strugglingjust to too many committees. You'll be asked to
do that. You have to work the same kind cine face today, the future will be brighter,
make it out of the lower ranks.
What, then , should women physicians of hours that your peers work. If you have Aschenbrener predicts.
"Things are definitely improving," she
children, you have to have shared respondo to bring about change?
said. "There are more male physicians in
"You have to find an area you can excel sibilities."
in and focus your interest," said Patricia
McGrath, at the American Medical positions of power who are really making
Duffner, chief of the medical staff at The Women's Association, said women need a great effort to help women along, who
Children's Hospital of Buffalo. Duffner to learn how to use the system to their take delight in seeing women succeed.
was one of the early specialists in pediatric advantage. "Doing a good job just isn't I've been very fortunate to have a number
brain tumors.
going to get you there. Women have to of very fine men assist me in ways I never
"If you do good work in a focused area, look at the political mechanisms men use asked for and in ways I wasn't aware of.
it's hard to be ignored," Duffner said. "If to get on committee, be appointed to And I've seen peopledoitforotherwomen.
you do a lot of little things, even if the committee chairs, get visibility. They have That is very gratifying."
+

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�WE~TERN NEW YORK WOMEN ~EE GAIN~
omen may be gaining power
ancy ielsen, M.D., paved the way
and influence in the medical for Western ew York's women physiprofession, if Western ew cians to be more involved in organized
York is an indication. The medicine by becoming the first woman
Erie County Medical Soci- president of the Erie County Medical Soety and the Eighth District ciety in 1989.
ielsen is a specialist in
Medical Society both are internal medicine and a clinical assistant
headed by women.
professor of microbiology at UB. She also
Mary Ann Bishara, M.D., is associated with the Buffalo Medical
was elected last May to represent physi- Group.
cians in the eight Western New York
"Once someone has been the first
counties that make up the eighth district. woman to do anything, it's easier for othBefore that, Bishara was president of the ers coming behind," ielsen said. "I don't
iagara County Medical Society for two have this load I carry around of blazing
years. She is chief of anesthesia at Mount trails" - among her other accomplishSt. Mary's Hospital in Niagara Falls.
Bishara said being a female has not
hindered her advancement in her field.
"I've always been accepted as an equal,"
she said. "I've never noticed any problems."
As head of the eighth district, Bishara
monitors problems that develop in the
member counties, acts as liaison between
the county societies and works with the
state medical society.
Amy Early, M.D., a specialist in
oncology and a clinical associate professor
in the Department of Medicine at UB, is
-Amy Early, M.D.
president of the county group. She practices with the Buffalo Medical Group.
"If someone had told me 15 years
ago I would be doing this," she said,
"I wouldn't have believed them. "
The local medical community is
very receptive to women, Early said.
" l think men for the most part have
been very supportive. The two people
who were most influential in my
career have been men. They have
gone out of their way to promote my
career. "
Early said the medical profession
could be perceived by women as a
large old boys network, which might
make them reluctant to jump in. But
that is changing, she said. "In medical organizations, men have gone
out and recruited women. The
American Medical Association is very
interested in female members. "
Amy Early, M.D.

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ments, Nielsen was the first woman chief
resident at Buffalo General Hospital. "But
one thing I did do as president of the
medical society was make sure young
talented women physicians interested in
the society had opportunities to sit on key
committees. That's what it's all about. "
Medical societies are still remarkably
male dominated, ielsen said, but not
necessarily because of conscious discrimination. "People in positions of power did
not know there were women interested in
being involved ," she said. "Once that
barrier was broken, ina couple of years the
executive board of our society was 50
percent female. That's how quickly it can
change."
Today, opportunities for women in
medicine are wide open, in Nielsen's opinion. "Women have always gravitated toward specialities such as pediatrics, obstetrics/gynecology and psychiatry," she
said. "But they are now going in to in temal
medicine, family practice and the last bastion- surgery. The surgical ranks, even
the traditionally male-dominated
subspecialities such as colo-rectal and urology, have female residents. There has
been enormous improvement compared
to a few years ago. "
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«&gt;

�BY ROBERT 5. WIEDER

When Dr. Stu Silverstein is examining an undressed patient, he likes to
save the balance test for last.

ttAs

they open their eyes, I tell them,
'You're fine- but somebody just stole
your
clothes.'"

A Spoonful of

Whensuturingminorlacerations.

Humor

he tries out standup comedy routines
on his patients. ttThey can't walk out
on me, and they don't dare heckle."
Moretothepoint, theyusuallylaugh,
and sail through the procedure before they know it. (We'll avoid any
puns on ttkeeping them in stitches.") •
EI!)

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aughter can play an important role in pain-control by distracting patients from pain and discomfort'," Univer_ _ _. .
_ sity at Buffalo

1

graduate (1981) Silverstein
says. In fact, as he wrote recently in California Physician,
he believes that "in the appropriate doses and settings, humor can help in the healing
process. It should be part of the
plan."
The role and application of
humor in medicine has been
widely discussed since publication of orman Cousins'
"Anatomy Of An Illness" but
Silverstein has taken it to heart
as a practitioner, advocate,
teacher - and comedian. A
pediatrics resident at San
Francisco's Children's Hospital, he is also a professional
stand up comic, a regional winner of the 1990 Merit Comedy
Competition.
Physician-comedian may not
be a traditional career combination like poet-musician or author-historian, but it has
worked well for him , as a physician, a
lecturer- he presents "Stand up Medicine Seminars" for physicians on the
virtues and uses of humor in medicine
-and an instructor, conducting workshops on comedy writing techniques for
health care and other professionals. He
also writes jokes tailored for medical
personneL
Silverstein represents an emerging
school of thought whose principle hypothesis is that humor can be a beneficial tool for the healing arts in a variety
of ways:
~ Humor can psychologically enhance the doctor-patient relationship and
the efficacy of treatment;
~ Humor provides discernible physiological benefits to the patient in several
clinical areas;
~ Humor is a mnemonic aid in giving
instructions to patients and in imparting

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information to students and lecture audiences;
~ Humor can improve the outlook
and productivity of medical staffs and, as
an emotional release valve, help reduce
stress overload among health professionals.

Patient Morale And
Cooperativeness
Humor helps to alleviate the feelings
of anxiety, apprehension and helplessness that patients experience in clinical
and hospital settings. A laugh can ease
tension and put a "serious" situation
into perspective. Silverstein recalls one
colleague who kidded patients as he
handed them their dressing gowns by
saying, "These quality designer gowns,
if purchased from Macy's, would go for
twice what we pay for them at the Men's
Wearhouse, allowing us to pass the sav-

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ings on to you ... "
Lightening the moment with obvious
parody made it easier for patients to don
this particularly grim and depersonalizinggarment, Silverstein notes.
"Sharing a laugh also makes it easier for
them to bring up their fears about more
serious issues - such as the bill," he
adds.
Humor also works to "socialize the
situation," by establishing the doctorpatient relationship in warmer, less formal terms. Given the current atmosphere of biotech medicine and industrialized health care, the healing process is
probably more in need of humanizing
than ever, and there is no more distinctively human activity than laughter.
Nothing enhances a doctor-patient
relationship, Silverstein suggests, like
the ability to laugh together and kid one
another. The end result, he feels, is

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�increasedpatientcomplianceandcooperation. To paraphrase Mary Poppins,
"just a spoonful of silliness helps the

me~~ci~~!~ ~~~e:~·,

clinical treatment
seems to be more effective when dispensed by someone the patient trusts,
likes .and feels close to. .And almost
mvanably, we are more mclmed to trust,
like and feel close to persons who add
laughtertoourlives. Humorthushelps
establish a bond between previously unrelated individuals in circumstances
where such a bond is most needed. As
Victor Borge says, "A laugh is the closest
distance between two people."
A joke made at the expense of the
clinical :ituation adds a "we're in this
together camaradene to a settmg otherwise characterized by inequality and

~,:0~;:~:!:\',:"~~~n~~~;'.:~~~~~~:~:l
BUFFALO

PHYSICIAN

Humor also works to
"socialize the situation," by establishing
the doctor-patient
relationship in
warmer, less formal
terms. Given the current atmosphere of
biotech medicine and
industrialized health
care, the healing proc e s s is p r 0 b a b l y m 0 r e
d f h u man l.z l n nee 0
1• ng than ever
and
t h ere l•s n 0 m 0 r e dish
1
tl n c t l v e y u man a c ti vi ty than laughter.
•

1

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BIOMEDICAL

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@)

�Top 10 Oscarwinning movies
if selected by
the "Academy"
of Pediatrics
By Stu Silverstein, M.D.

lQ
I

Indianna Jones and the
Precipitous Delivery

9
8
7
6

Saturday ight Fever ...
without Origin
Dirty Harry in "Tell me
that it's just the flu
doctor and I'll blow
your head clean off."
Sophie's Choice ...
Augmentin
The Man Who Fell to
Earth on Librium

s

ET makes a Child
Protective Services referral

4
3
2
l

Sally Field in "Not
Without My ... Lawyer"
King Kong Rules Out
Sepsis

Godzilla vs. Fecal
Impaction
Rosemary's Baby Gets a
Psych Consult

sphere, lending a note of easy familiarity
to impersonal protocol. It leavens uneasiness with laughter.
Humor can be a lighthearted
acknowledgement of the loss of privacy
and control that patients are subjected to
by medical procedures. This isn't to
suggest that practitioners incorporate
handpuppets, novelty bow-ties or five
minutes of bedpan gags into their exami-

~

BUFFALO

PHYSI

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nations or instructions. It is to suggest deal" matters, especially when patient
that the inclusion of banter, such as cooperation is essential. And when im"These jokes are free, but we do have a parting instructions for self-medication
two-enema minimum," can bring a valu- and self-monitoring, a joke or two may
able humanizing quality to an otherwise be an important mnemonic aid. A patient too disconcerted by the gravity of
dreary medical context.
the
situation to remember specific proAfter all, underlying the increasing
cedures
might very well recall a joke
corporate formality, esoteric technology
and confusing protocol of modern medi- designed to remind him or her of those
cine, the fundamental task of the healer procedures.
For example, when prescribing mediremains to make the patient feel better.
And few things accomplish this more cation that may impair the patient's motor
immediately than the simple act oflaugh- functions, the warning "Don't operate
any vehicle, machinery or sexual partter.
ner over 300 pounds" - can engrave the
PhysiologicalBenefits caveat into the patient's memory more
Silverstein doesn't actually extol hu- deeply than a dry recitation of the stanmor as a clinical panacea, but if laughter dard precautions. Humor, in short, can
were a pharmaceutical, he'd attract the put things in more engaging, and memoattention of the FDA. "For bedridden rable, terms.
When it comes to delivering a progpatients, it can improve the circulation
nosis,
if the situation is not all that serialmost like an aerobic workout. It stimuhumor
is the most immediate and
ous,
lates the diaphragm and can induce
coughing, which is important to pneu- persuasive way to underscore that fact.
monia-prone patients in stasis, and more Conversely, if the situation is serious,
fun than a respiratory therapist. Muscle- humor can help soften the impact of that
tension headaches often disappear after reality, can provide comic respite from
laughing at comedy. Laughter can lower intense emotions and can be a vital tool
blood pressure, improve digestion by for managing or minimizing the resultstimulating GI blood flow - important ant anxiety or despair. "At best, you'll
when you're dealing with hospital food live a long and normal life. At worst,
- and as a distraction from pain, can you'll have the satisfaction of making
your health insurance salesman wish
reduce the need for medications."
he'd never met you ."
Humor similarly helps to convey
Instructional And
boilerplate
data and terminology to lisMnemonic Aid.
teners
during
lectures, seminars and
Humor can do wonders for doctorrounds,
according
to Silverstein, a vetpatient communication by getting the
patient's attention, by helping to express eran of all three. "The professors,
things in a more comprehensible way attendings and presenters who work
and as a memory facilitator. Given that humor into their material are the ones
the diagnosic interaction is often com- we usually remember best. They keep us
plicated by the distraction of patient interested and attentive. ln fact, the
apprehension, a lighthearted note can more serious the message, the more imalleviate patient misgivings, and thereby portant humor can be."
make procedures and instructions less
formidable. For instance, the declara- Stress Reduction For
tion that, "We'll need samples of your Health Professionals
stool, blood, semen and urine," can beMedicine's very intensity, Silverstein
come far less stark and ominous an an- feels, makes humor a vital mechanism
nouncement if followed by, "Gee, maybe for decreasing the stress inherent in its
I should just take your underwear. "
practice: "A sense of humor helps keep
Humor can convert impersonal de- us from being swallowed up emotionmands made on the patient into "no big ally." The simple ability to joke about

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---~~~

crisis situations, wo rkload pressures and
bureaucratic frustrations can foresta ll
burnout and discordant overreaction.
Studies of hum or in non-medi cal
workplaces show it boosts productivity,
aids mental acuity and dimi nishes alienation , conflict and absenteeism. Most
importantl y, it can make th e cl in ica l en-

vironment less a source of dread and
depression.
There is, of course, so me antipathy
among pro fessio nals toward compromising th e "serious business" of medicin e with "undignified" lightheartedness. But, Silverstein poi nts out, "Humor has always been part of our profes-

~

tu "Schrick Doc" Silverstein,
M.D., a University at Buffalo
grad (1981) , began doing comedy as a student here , back when
medicine was still a gleam in his
agenda.
"I lived in Ellicot Complex, and
I knew I'd need humor when they
passed out Elavil along with the
dorm keys. ln Ellicot, people would
turn the sound down on the TV and
have me do the dialogue. I did
impressions of professors, Jimmy
Carter, Menachem Begin, Mick
Jagger. People said l should do
comedy, so l went on at the Rathskeller in Squire Hall, which I think
is now a dental school; somehow
appropriate. I did mock press conferences, I did a lot of material about
Buffalo- I was from Brooklyn and
used to wonder what people meant
by, 'Do you drive a kerr? '"
Now a pediatrics resident and
working comic, Silverstein has combined his two vocations into a flourishing enterprise, delivering what
he calls Standup Medicine Seminars on "The Power of Humor in
Medical Practice" to groups of medical professionals, often for Continuing Medical Education credits,
and conducting workshops on comedy writing techniques for physicians wishing to integrate humor
into their practices and presentations. His "seminar circuit" ranges
from California to the east and
midwest, and he has been featured
in newspapers and magazines, and
on ABC's World News Tonight. +

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sional lives, and it's usually a welcome
relief. "
The "pro-humor" advocates might argue that it is precisely because medicine is
both serious and a business that it stands
to benefit fro m those humanizing, comforting and even tranquilizing qualities
that "comic relief' so uniquely provides. +

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.

I

Buffalo Academy of Medicine
presents Kart Haas
OF MEDICINE , MUSIC AND THE HUMANTIES

arl Haas, the radio host of the
popular "Adventures in Good
Music," must know that there
always are doctors in the concert
hall. And not just because he
hears their beepers. Doctors are
there because medicine and music have
a common theme, which is healing. They
are there too because to be effective
physicians they must not shut themselves in a diagnostic world.
"Medicine is life," Haas told an audience oflargely physicians who had come
to his piano recital and lecture last October in UB's Katharine Cornell Theatre.
"Medicine is life-healing," he said, expanding his theme. "So is music."
Haas's appearance was the opening
event in the Buffalo Academy of
Medicine's Centennial Lecture Series, a
series which this season is prescribing
doses of the humanities. Haas' topic was
"Medicine, Music and the Humanities."
During the course of it he examined
several of the great composers, and named
a number of scientific and medical discoveries that were footnotes to his text of
musical appreciation.
"A musician is the poorer for going
through life only as a musician," Haas
said. "And physicians, too." The "kinship" of music and science, he said, is
"creativity." "Medicine," he dared say,
"is as much a matter of talent as music."
Haas chose to begin his musical examination with Bach, the composer who
lived from 1685 to 1750, whose music
summed up the achievements of the baroque period in music, and who, as Haas
fl)

BUFFALO

PHYSICIAN

"Medicine is life.
Medicine is life-healing.
So is music. A musician
is the poorer for going
through life only as a
musician. And physicians, too. The kinship
of music and science is
creativity. Medicine is as
much a matter of talent
as music."

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reminded, produced in addition to great
contrapuntal works, 20 children. The
piece he played by Bach was chosen for
its "melodious beauty" rather than its
intellectual rigor.
The scientific achievement that Haas
chose for his footnote to Bach was the
first recorded attempt to measure the
rate of the heartbeat- a very appropriate choice, for one of the notable characteristics of Bach's music is its strong and
steady rhythmic pulse.
During Bach's lifetime scientists were
first envisioning a vaccine for smallpox.
During the lifetime of Mozart they were
discovering a way to fight dropsy. Mozart
died mysteriously, perhaps as the result
of an epidemic. He lived to be 35, and
died 200 years ago. Since then, it might
be argued, there has been more good
medicine than good music.
For Haas, Mozart represents a psychological advance in music. He played
the D minor Fantasia by Mozart, in which
he believes the composer bares his soul.
"He wasn't a regular guy," Haas said,
"and we can only understand him
through his music."
Haas remarked that each time he plays
Mozart he discovers something new
about the composer. And he suggested
that a physician too should find something new each time he treats a patient.
The other composers examined by
Haas were Beethoven, Schumann,
Gershwin and Debussy. Haas mentioned
a few scientific discoveries during their
lives. The vaccination against smallpox
was discovered, and the stethoscope was
invented, during the time of Beethoven,
and penicillin was discovered during the
lifetime of Gershwin.
Beethoven was going deaf, and he was
dejected, Haas said, when he wrote his
last will in 1802. "Music was the refuge
from all the tribulations that befell him,"
Haas said. He played the slow movement of the Pathetique Sonata, which

SCIENTIST

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• • • • •••• •
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Karl Haas presents uMedicine, Music and the Humanities" as the opening event of the Buffalo Academy of Medicine's Centennial lecture Series.

romanticism: "There is no such thing as
a creative mind working in a vacuum,"
Haas said.
At the piano Haas did not venture
beyond Gershwin, who died in 193 7 of a
brain tumor. (He did, however, make
passing praise of Leonard Bernstein and
Aaron Copland, whom he called great,
and he told especially of his admiration
for Bernstein, who once impressed him
at Tanglewood by being able to sing all
the roles of Carmen during a class for
conductors.) Haas played a piano blues
by Gershwin, and he made it sound
urgent.

happens to be the theme he has used for
his radio program, ever since it first aired
in Detroit 32 years ago (one year for each
of Beethoven's piano sonatas).
Haas gave a heartfelt performance of
an Arabesque for piano by Schumann,
the great romantic composer who suffered from mental disorders. If you
would understand Schumann, Haas suggested, you would best listen to the dual
personality expressed in his music. Footnotes to Schumann were not scientific,
but included fleeting references to other
romantic artists, such as Delacroix, Hugo,
Goethe and Schiller. They were all on to

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The "vague chords" and impressionism of Debussy's Prelude from Pour le
Piano concluded the musical part of the
program, with wonderful washes of notes
and harmonies.
The harmonies of music do go far in
making us whole, Haas suggested. At
the close he told of a period of suffering
in own life, when his sister was dying,
and he found strength in the music of the
slow movement of Beethoven's Emperor
Concerto. It was for him a powerful
example of the healing effect of musicof the composer as physician.
+
-BY

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THOMAS

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PUTNAM

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$

�•

... . ............................ ... ............. .. .... . .......... . .............. .. ... ... . .

.

I

SSOO,OOO grant received
to estabfish supercomputing
network for research

Med school oHers unique
medical computing course
he practice of medicine, like
nearly every other profession, has
been revolutionized by computers. A dazzling array of computer
programs is available to the physician at the touch of a keystroke,
providing access to everything from full
medical texts to electronic mail consultations with colleagues.
Students at the School of Medicine
and Biomedical Sciences are learning
how to use this computer wizardry in a
course unique to medical schools across
the country. The course is distinctive in
two ways: it is mandatory for students
and it allows them to apply all the technical tools, interactively, to real-life cases.
"What we're doing now is quite different from what most schools are doing," said john Loonsk, M.D. , director of
academic computing. "There are some
schools with electives in medical computing, and some schools that have mandatory computer literacy courses. But
what we've been doing is requiring a
course specifically oriented to the use of

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BUFFALO

PHYSICIAN

computers in medicine."
Each student is assigned a case to
diagnose and treat using the full array of
computer-based records and medical
information systems that will be available in hospitals in the future. Students
have access to the patient's computerized medical records and laboratory and
drug reports, as well as computer images
of X-rays or CAT scans.
Students can use a medical expert
system that helps interpret findings and
make decisions; a data base of medical
literature; full texts of reference books,
clinical manuals and journal articles; the
full Physicians' Desk Reference of drugs; a
program that identifies interactions between food and drugs, and electronic
mail for soliciting opinions from other
physicians.
Loonsk said the students respond well
to the new technology. "The time spent
on computers is definitely very beneficial," he said. Many come back to us and
admit that they had to struggle some, but
now that they're in a clinical setting and
are seeing some of these tools at work,
they're glad they had the experience." +
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he State University of New York
at Buffalo has received a $500,000
grant to set up a supercomputing
network that will place it at the
vanguard of the emerging field of
biomedical supercomputing.
The funding comes as a $300,000
grant from the National Science Foundation and a $200,000 contribution from
the University at Buffalo.
The new system, which is 500 times
faster than the current system, will allow
faculty to intensify their work in two
important research areas: biomedical
imaging and the study of ion channels,
tunnel-like structures that control the
electrical behavior of cells.
"Only a handful of medical schools
have this kind of facility available for
biomedical research," said Anthony L.
Auerbach, professor of biophysics and
director of the supercomputer project.
"And I'm not aware of any other research
university in the country having this
level of research power available for ion
channel studies."
Knowledge of how ion channels work
can provide new information on brain
and muscle function and the causes of
certain diseases.
"This supercomputer will allow us to
do experiments we could only dream of
doing before," saidjoseph T. Spence, associate dean for research
and graduate studies
for the medical school.
The supercomputer
will support the work
ofbiophysical sciences
professor Frederick Sachs, physiology professor Donald S. Faber and Auerbach. +
-

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••••~•
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UB's rural training track in
famUy medicine accredited

in rural areas, where the need for primary care physicians is great.
The rural campus currently is staffed
by two physicians and two resident physicians. It will eventually accommodate
four physicians and resident physicians,
plus a number of medical students who
will rotate through the center. The practice will serve parts of two counties with
a population of 21,000. Two private
physicians, neither of whom offers prenatal care, currently practice in the area.
By 1992, rural campus visits are expected to reach 18,000 per year.
The Residency review Committee of
the Accreditation Council on Medical
Education has accredited similar programs at the University of Washington
+
and the University of ebraska.

he rural training track in family
medicine at UB has been accredited by the Residency Review
Committee of the Accreditation
Council on Medical Education,
making it one of three universities in the country approved to train
primary care physicians
to be country doctors.
The rural training program is part
of a three-year program. Resident physicians spend the
first year in Buffaloarea hospitals and
clinics affiliated wit
the medical school,
and the remaining
two years at UB's
Rural
Health
Campus on the
grounds of Cuba
Memorial Hospital in Cuba,
ew York. Cuba is a community of about 1,700 people 70 miles
south of Buffalo in sparsely populated
Allegany County.
The resident physicians live and practice in the area, seeing patients at the
rural campus and Cuba Memorial Hospital and Olean General Hospital, cosponsors of the project.
"Residents tend to practice near the
area where they did their training," said
Thomas Rosenthal, M.D., clinical associate professor of family medicine and
director of the project. "For the past 40
years, the American medical training
system has focused on large urban institutions. "
Rosenthal hopes exposing residents
to a country practice will help reverse
that trend and encourage them to settle

BUFFALO

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This year's forum featured the work
of 93 students, the largest field since the
competition began.
Projects ranged from a study of the
effects of cocaine on the brain of a rat, to
an analysis of heart disease risk factors in
an old order Mennonite community. One
student's research took him to Kenya,
where he studied health and disease
among the Rendille.
Most participants conducted their
research with the help of summer research fellowships, working at UB and
other institutions.
Forum particpants presented their
research in poster form . UB faculty
served as judges; each display was reviewed by three judges. More than 60
UB faculty took part in the judging. +

AKER

Research forum features
wen of 93 medical students
B medical students vyed for
$500 prizes and the chance to
take their research to a national
competition during the 11th
annual Medical Student Research Forum in early December.

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Medical students present their research during the
11th annual Medical Student Research Farum.

ENTIST

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�rfi,iil".... ............ .... ..... ..... ................ ........................ .. ......... ... .... .
~
Fisher wins award for
excellence in writing

N

adine Fisher, Ed.D. , a research
scientist in rehabilitation medicine, recently received the 1990
Sidney Licht Award for Excellence in Scientific Writing from
the American Congress of Rehabilitation Medicine. The award was presented
in late October.
Fisher received her doctorate last May ~
from the Department of Exercise Sci- ~
ence. Her research has been published v;
Nadine Fisher, Ed.D.
extensively in the Archives of Physical
Medicine and Rehabilitation Medicine.
Fisher received the award along with
fellow authors professor David R.
Pendergast, Ed. D., and professor emeriames H. Cosgriff,
tus Evan C. Calkins, M.D. , for their
Jr. , M.D. , was recarticle "Maximal Isometric Torque of
ognized for his
Knee Extension as a Function of Muscle
contributions to
Length in Subjects of Advancing Age ,"
trauma care at a
published in the September 1990 issue
dinner in November at
+ the Hyatt Regency Bufof Archives.
falo. Nationally known trauma surgeon, James]. "Red" Duke, Jr. , M.D.,
delivered the keynote address on the
effects of traumatic injuries and the ecoradley P. Fuhrman, M.D., was re- nomic factors of trauma care. Orgacently appointed chief of the divi- nized by the Medical Society of the
sion of critical care at The County of Erie and co-sponsored by the
Buffalo Medical Group and IndepenChildren's Hospital of Buffalo.
Fuhrman, a UB medical school dent Health, the event was a fundraiser
professor, is responsible for overseeing for Mercy Flight, Western ew York's
clinical research and training programs emergency medical care helicopter serin the pediatric intensive care unit. He vice.
Cosgriff, an assistant clinical professor
will also participate in
of surgery since 1962, has served as
the modernization of
director of Mercy Flight, chief of trauma
the unit and impleservice at Sisters of Charity Hospital and
ment new medical
chairman of the New York State Commanagement promittee on Trauma.
grams as well as build
Duke, a Texas native, is a nationally
a fellowship program.
recognized
authority on trauma care.
Fuhrman was previously assistant director of the intensive care unit at Pitts- He established Houston's Hermann Hosburgh Children's Hospital.
+ pital Life Flight and help found the

Cosgriff honored at
Mercy Flight benefit

J

Fuhrman appointed chief
of critical care at CHOB

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OMEDICAL

American
Trauma Society .
A
1989 candidate for the
position of
Surgeon
General of
the United
States , he
was host of
the PBS prog r a m
Body watch .
He currently serves as professor of surgery at the University of Texas Medical
School at Houston.
+

Bettigole named Red Cross
blood services director

R

ichard Bettigole, M.D., an associate professor of medicine and
clinical associate professor of pathology , has been named medical
director of the American Red
Cross Blood Services Buffalo Region.
Bettigole previously served as head
of hematology laboratories, blood bank and
clinical hematology at
Erie County Medical
Center. He is a graduate of Yale University and Columbia
University Medical School.
+

John Naughton, M.D., right, dean of the medical
school, receives an Award of Excellence at the 19th
Annual Black Achievers Dinner held last October.

SCIENTIST

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James Platt White
Societr holds
annua meeting
embers of the
james Platt White
Society were honored
at
the
society's sixth annual meeting held
last October 18 at the Country Club of Buffalo.
joseph T. Spence, Ph.D.,
associate dean for research
and graduate studies, delivered a slide presentation on
plans for the medical school's
new biomedical sciences
building.
The dinner dance was held
to honor society members,
who have made annual contributions of $1,000 of more.
The members of the james
Platt White Society for 1991
are:
Dr. Kenneth Alford
Dr. William S. Andaloro
Dr. Kenneth Z. Altshuler
Dr. Amos Ar
Drs. Kevin and Elizabeth Barlog
Dr. jared Barlow
Dr. Charles D. Bauer
Dr. Richard A. Berkson
Dr. Willard Bernhoft
Dr. Russell W. Bessette
Dr. Theodore Bistany
Dr. Dennis L. Bordan
Dr. and Mrs. Harold Brody
Dr. Robert L. Brown
Dr. August A. Bruno
Dr. Elaine M. Bukowski
Dr. and Mrs. Irwin Burstein
Dr. David W. Butsch
Ms. janet F. Butsch
Dr. john L. Butsch
Dr. Evan Calkins
Dr. icholas]. Capuana

BUFFALO

Dr.
Dr.
Dr.
Dr.
Dr.
Dr.
Dr.

.fl l

Michael E. Cohen
and Mrs. joseph A. Chazan
George H. Christ
Daniel E. Curtin
Roger S. Dayer
Carlo E. DeSantis
PeterS. D'Arrigo

Dr. Edward Diao
Dr. Thomas A. Donohue
Drs. Thomas C. Doolittle and Leslie
Doolittle
Dr. Kenneth H. Eckhert
Dr. Robert Einhorn
Dr. and Mrs. George M. Ellis
Dr. Leon Farhi
Dr. Daniel Fahey and Dr. Marie
Runfola
Dr. Donald M. Fisher
Dr. Grant T. Fisher
Dr. jack C. Fisher
Dr. Richard R. Gacek
Dr. Matthew A. Gajewski
Dr. Kenneth L. Gayles
Dr. john W. Gibbs, jr.
Dr. Allen Goldfarb
Dr. Seymour Grauer
Dr. Harvey Greenberg
Dr. Mala Gupta
Dr. Thomas]. Guttuso
Dr. Eugene Hanavan
Mr. and Mrs. Edward Hansen
Dr. and Mrs. Gerald Hardner
Dr. Reid R. Heffner, Jr.
Dr. Orvan W. Hess
Dr. Takeshi Homma
Dr. Bradley Hull
Dr. Annabel M. Irons
Dr. and Mrs. Kenneth L. jewel
Dr. Charles Alexander joy
Dr. Herbenjoyce
Dr. Stephen T. joyce
Dr. james R. Kanski
Dr. Ivan W. Kuhl
Dr. joseph L. Kunz
Dr. Marvin Z. Kurian
Dr. Andre Lascari
Dr. Eugene V. Leslie
Dr. Lawrence M. Lesser
Dr. and Mrs. Harold]. Levy
Dr. Stanley Lewin
Dr. jack Lippes

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The James Platt White Society's sixth annual meeting was held in October.
Dr.
Dr.
Dr.
Dr.
Dr.

Don L. Maunz
Robert C. McCormick
William . Mcintosh
Harry L. Metcalf
Merrill L. Miller
Dr. Eugene R. Mindell

Dr. joseph F. Monte
Dr. john D. Mountain
Dr. Richard L. Munk
Dr. Arthur Mruczek
Dr. Dennis adler
Dr. Richard]. agel
Dr. Masao akandakari
Dr. Richard B. Narins
Dr. and Mrs. john Naughton
Dr. David H. ichols
Dr. john]. O'Connor
Dr. Benjamin E. Obletz
Dr. Yasuyo Ohta
Dr. Elizabeth P. Olmsted
Dr. Arthur Otis
Dr. Donald N. Pachuta
Dr. and Mrs. Robert]. Patterson
Dr. and Mrs. joel Paull
Dr. Deming L. Payne
Dr. Clayton A. Peimer
Dr. Victor L. Pellicano
Dr. james F. Phillips
Dr. He rbert S. Pirson
Dr.
Dr.
Dr.
Dr.
Dr.
Dr.

Ben Rappole
Frederic D. Regan
Albert C. Rekate
Frank T. Riforgiato
Alben G. Rowe
Richard R. Romanowski

BIOMEDICAL

SCIENTIST

Dr. and Mrs. Charles H. Rosenberg
Miss Thelma Sanes
Dr. Arthur]. Schaefer
Dr. Robert . Schnitzler
Dr. Roy E. Seibel
Dr. joseph I. Schultz
Dr. Elizabeth G. Serrage
Dr. Edward Shanbrom
Dr. and Mrs. Samuel Shatkin
Dr. john B. Sheffer
Miss Alice Simpson
Dr. Richard A. Smith
Dr. John E. Spoor
Dr. William Sternfeld
Dr. Gerald Sufrin
Dr. Eugene M. Sullivan, Jr.
Dr. Michael A. Sullivan
Dr. Hiroshi Tazawa
Dr. MichaelS. Taxier
Dr. Charles S. Tirone
Dr. W . William Tornow
Dr. Anthony C. Trippi
Dr. Ronald H. Usiak
Dr. john P. Visco
Dr. Barbara Von Schmidt
Dr. Philip Wels
Dr. Paul H. Wierzbieniec
Dr. Gary]. Wilcox
Dr. james S. Williams
Dr. john R. Wright
Dr. Hajima Yamabayashi
Dr. Tetsuro Yokoyama
Dr. Wende W . Young
Dr. Franklin Zeplowitz
Dr. and Mrs. David C. Ziegler

WINTER

1992

ED

�•

········ · · · · · ····· · ········ · ····· · ···· · ······ · ··· · ····················· ·· ······ · ········ ··

I

1

9

2

s

0

ROSARI E ROSSELL BENDER

medical director of the Urgent

Maryland. Theyhavefivedaughters (including five-year-old trip-

'20 , of Ft. Lauderdale , Florida, is

Care Department of the Western

lets).

JOHN

published in 1991.

9

JOSEPH

3
R.

0

SAAB '34 ,

ANDERSON

'67 ,

ew York Medical Park, was Board

the author of Don't Say Goodbye

1

R .

partment of Medicine at johns

in 1989.

Hopkins.

1

WALTER Z . SCHWEBEL '38 ,

is

9

7

0

s

ROBERT P . GALE '70 , of Los
Angeles, California, is a section

from general practice and is living
in Hamburg, New York

editor of a new journal entitled

Robert Gole, M.D.

and is an instructor in the De-

certified in emergency medicine

s
retired

He is in private practice

Cell Transplantation.

JAMES A . SOLOMON '79 ,

is

assistant clinical professor of dermatology and director of the International Centre for Applied Immunologic Principles at Tufts
Medical School/Bay State Medical

still active in pediatrics and is the

Center.

has

MELVIN POHL '76 , has returned

been appointed to the senior-acLive staff at the Memorial Hospital

to Las Vegas as a family practitio-

of Salem, New jersey (thisappoint-

author of The Caregivers' jour-

JANET M . WILLIAMS '88 ,

ment is only possible after 25 years

ney, When you Love Someone With

her husband john ]. Barbaccia

of service to the hospital).

Aids, published by Harpers.

'88, announce the birth of their

tired in 1982 and enjoys living in

STEPHEN C . SCHE I BER '64 ,

ORESTES G . ROSABAL '77 ,

Jupiter, Florida for six months

the executive vice-president of the

who serves the Southern Medi-

each year.

liams is an attending in emer-

American Board ofPsychiatry and

cal Association as Councilor for

gency medicine at Allegheny

director of the Physically Handicapped Children's Program of
Rennsselaer County, New York.

1

9

4

0

s

A . ARTHUR GRABAU '45 ,

re-

MYRON E . W ILLIAMS , JR . , '46 ,

tells us that he retired in july from
Family Practice and Geriatrics.

1

9

5

0

s

JOHN J . LAMAR , JR . , '63 ,

ner and addictionist. He is the

1

9

8

s

0

and

daughter , Katherine Moore
Barbaccia onjuly 17, 1991. Wil-

Neurology, serves on the Edito-

the State of Florida, attended their

General Hospital; Barbaccia is

rial Board of Academic Psychiatry

85th Annual Scientific Assembly

chief resident in anesthesiology

and is a member of the Board of

in Atlanta , Georgia during

at Mercy Hospital.

Trustees for the Group for the

November.

Advancement of Psychiatry.
JAN ICE DENISE W IL LI AMS '77 ,

OBITUARIES
HENRY J . WISER '34

died in

has a

ROBERT M . TABACHNIKOFF

private practice in neurology in

'66 , was deployed inAugust1990,

gynecology at the U.S. Naval Hos-

Winter Park, Florida August 22 ,

Honolulu, Hawaii, and is doing

while chief of the Obstetrics and

pital in Patuxent River, Maryland.

1991.

research in the epidemiology of
stroke and Parkinson's Disease.

Gynecology Departmental Keller
Hospital, West Point, New York,

R ICHARD F . BUSCH '78 ,

and served with the 46th Combat

assistant clinical professor of sur-

Harry 0. Westphal '58, of Palm

Support Hospital in Saudi Arabia

City, Florida, retiredjuly, 1991.

until mid-Aprill99L

gery (otolaryngology) at the University of California at San Di-

JORDAN S . POPPER '56 ,

is an attending in obstetrics and

ego, School of Medicine.

1

9

6

0

s

MICHAEL I. WE I NTRAUB '66 ,

is

His

article "Intermaxillary Fixation

THOMAS J . KAISER '43

died in

May, 1991.
diedjuly
15, 1991, at his home in

JOHN WILLIAMS '43 ,

Cassadaga, New York, after a battle
with cancer.

com-

co-edited a book with Arthur E.

pleted the three-month Advanced

Fass, M.D. ,onthecombinedmedi-

with Intra Oral Cortical Bone
Screws" was published in the

Management Program at the

cal disciplines of neurology and

December 1991 issue of The

july 11 , 1991 following a six-

Harvard Business School in No-

cardiology, Heart and Brain: In-

Laryngoscope.

year battle with lymphoma.

vember, 1991. He is medical di-

teractions of Cardiac and Neur·o-

rector of Kaiser Permanente in

logic Disease. Weintraub also co-

KENNETH GLICK '78 ,

Orange County, California

authored one of the book's chapters with Allan Rothman, M.D ..

wife Sandy live in Baltimore,

KENNETH E . BELL '61 ,

G

BUFFALO

PHYSICIAN

A

N

0

BIOMEDICAL

HARVEY Z . KLEIN '57 ,

died on

and his

SCIENTIST

WINTER

1

9

9

2

��BUFFALO PHYSICIAN AND BIOMEDICAL SCIENTIST
STATE UNIVERSITY OF NEW YORK AT BUFFALO
3435 MAIN STREET
BUFFALO NEW YORK 14214

ADDRESS CORRECTION REQUESTED

Non-Profit Org.
U.S. Postage
PAID
Buffalo, NY
Permit No. 311

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                    <text>�THE BUFFALO PHYS I CIAN
AND BIOM E DICAL SCIENTIST

Dear Alumni and Supporters of the UB Medical School:

Volume 26, Number 2

N

DIRECTOR OF PUBLICATIONS

NancyTobm
EDITOR

Nanelte Tramont Kolhg, R.N.
ART DIRECTOR

Alan J. Kegler
ASSOCIATE AR T D I RECTOR

Scolt Robert fricker
CONTRIBUTING EDITOR

Arthur Page
STATE UN I VERS I TY OF NEW
Y ORK A T BU F FALO SCHOOL
O F M E D I CINE AND
BI OM E DICA L SC I ENCES

Or John Naughton, V1ce President for
Clmical Affairs, Dean
EDITOR I AL BOARD

Or John A Richert, Chairman
Or Harold Brody
Or. Glen Gresham
Or. Nedra Hamson
Or. Jame&gt; Kansk1
Mr. Harold Llll
Or. Charles Paganelh
Or. Luther Robmson
Or. Thomas Rosenthal
Or. Saleela Suresh
Or Burton Singerman
Or. Stephen Spauldmg
Or Nelson Torre
Mr Edward Wenzke
Or. Jerome Yates

ineteen ninety-two is off to a busy and difficult start. The good news is that the
demolition project of the back-end of Harriman Hall is almost completed and
construction of the new 110,000-square-foot research building should be underway
by April1. Already one can sense the "campus-like" quality that will exist once these
projects are completed. Indeed, UB will have a core medical-health-science campus of
which we all can be proud.
The bad news is that New York State's fiscal crisis will take yet another toll on
the level of available state operating revenues. The reductions for 1992-93 will approximate $1.5 million and 25 full-time equivalents. The cumulative reductions since 1990 will
total almost $3.5 million by March 31, 1993. lt is very fortunate that we experienced
necessary growth and program development throughout the 1980s.
O nly through the mechanisms of increased private giving, an expanded research program and the institution of the faculty practice
p lan ar~ we able to cope wtth such large reductions in state funding.
Even wtth these resources we w1ll be hard pressed to maintain the pace
that 1s needed to be a med1cal school of top-rank. We are committed
to do our best. Your help and support will be even more important in
th_e months and years ahead. The faculty, students and 1 know you
w1ll contmue to prov1de tt. We commit ourselves to maintain
educational quality and to strive to keep your medical school among
the leaders in the country.
Sincerely,

j ohn Naughton, M. D.

Vice President for Clinical Affairs
Dean, School of Medicine and Biomedical Sciences

T E A C HIN G HOSPI T ALS AND
LI AI S ON S

Batavia VA Medical Center
Buffalo General Hospital
Michael Shaw
Buffalo VA Medical Center
Paula Pcdene
ChHdren's llosp11al of Buffalo
Karen Dryja-Swiersh1
Eric County Med1cal Center
Mary Northen
Mercy Hospital
MHiard f'Himore llosp1ta!s
Frank Sava
Roswell Park Cancer Institute
judith Rice
S1sters of Chanty llospnal
Dennis McCarthy
© The State University of 1\ew York at
Buffalo
The Buffalo Physician and Bwmed1cal Scientist IS published quarterly by the State
Umversity of New York at Buffalo School
of Med1cinc and Biomedical Sciences and
the Office of Pubhcauons. ll "sent, free of
charge, to alumm, faculty, students, residents and fncnds. The staff reserves the
right to ed11 all copy and submisSions accepted for publication.
Address questions, commenlS and submissions to: Editor, The Buffalo Physician
and Biomedical Scienllsl, Stale University
of New York at Buffalo, Umversity Pubhcallons, 136 Crofts Hall, Buffalo, New York
14260
Send address changes 10: The Buffalo Physician and Biomedical Scientist, 146 CFS
Addition, 3435 Main Street, Buffalo, New
York l4214

Dear Fellow Alumni:

W

ith an exciting and informative Spring Clinical Day and Reunion Weekend just
pa~t, I would hke to thank all of the board members who made ita reality. Dr. Mary
Altce Kelly, as Program Cha1r, Dr. Margaret Parowski as Exhibits Chair and all of
the others, made this event a big success.
'
I would like to thank all the alumni who supported the many activities of the
Association. You helped not only the medical school, but many medical students in their
educational pursuits.
We are a strong and healthy Alumni Association because
you have shown that you care.
Best wishes for a wonderful and healthy summer!
Sincerely,

J

~~·~
Nedra ]. Harrison, M.D., '77

�VOL . 26 , No . 2
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SPR ING 1992

..... . . . . ..... . . . .....

II Research

IJ Hospital News
IJ Perspective on Healing e A pictorial feature on UB's
Smokers who quit
smoking after bypass
surgery were more
interested in saving
money than their lives,
according to UB
researchers. Page 3.

Robert L. Brown History of Medicine Collection.

DJ ASpoonful of Humor

m

Charting the Secrets of Life e As part of the Human
Genome Project, researchers at Roswell Park Cancer Institute are unraveling the mysteries of our
genes.

~~ It Hurts to Be Beautiful e Once nearly exclusively the
UB researchers see a relationship
between lower blood pressure
and people with extensive social
networks. Page 2.

province of women, cosmetic surgery is fast becoming an equal opportunity operation as more
and more men flock to surgeons than ever before.

m
m

Medical School
People

• An early 1900s gas X-ray tube
from UB's History of Medicine
Collection. Page 6.

EZJ Classnotes

After a fouryear hiatus to
do standup
comedy, a
physician returns
to residency.
Page 14.

* C

0

V

E

R

Apottery phrenology bust,
ca. 1855, from the Robert
L. Brown History of
Medicine Collection.

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"

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North American Symptomatic Carotid
Endarterectomy Trial to determine if
patients with 30 to 69 percent narrowing
of the arteries would also benefit from
surgery.
+

National Eye Institute
funds UB retina research

VA study shows vascular
surgery may help prevent
strokes
Department of Veterans Affairs
cooperative study concludes
that carotid endarterectomy surgery should be performed on
patients who are at high risk for
stroke.
Linda Hershey, M.D., chief of neurology at the Buffalo VA Medical Center
and UB associate professor of neurology,
is one of the authors of the report published in December in the journal of the
American Medical Association.
"This validates the usefulness of surgery in high-grade stenosis, which can
lead to strokes," Hershey saicJ. She added
the study results showed that half of the
patients who were randomly selected
and treated with surgery and aspirin
therapy had fewer strokes than those
who were receivingaspi rin therapy alone.
Thirteen patients from the Buffalo VA
Medical Centerwereenrolled in the study
that included 189 patients nationwide.
The Buffalo study group will join the

8

BUFFALO

PHYSICIAN

alcolm A. Slaughter, Ph.D.,
UB associate professor ofbiophysical science and ophthalmology, has received a
$143,000 grant from the National Eye Institute to continue research into how the retina functions.
Specifically, he will study how neurons in the retina interact with one another. "There have been a lot of advances in eye research in recent years,"
Slaughter said, "but when it comes down
to understanding the retina, we are just
getting some real questions answered."
Slaughter and his colleagues have been
studying retinal function for nearly a
decade. One of their discoveries revealed that the eye sees a light going on
and a light going off in different parts of
theretiM.
+

Study finds relationship
between social contad and
lower blood pressure
UB study of social interaction
and its relationship to blood pressure shows that people with extensive social networks have
lower blood pressure than people
with little social contact.
And while connections with others in
general were associated with lower blood
pressure, certain aspects in particularthe number of siblings for women and
household size and club participation
for men - appeared to affect blood

AND

BIOMEDICAL

pressure more than others.
The study was conducted by researchers in the University at Buffalo's Department of Social and Preventive Medicine,
headed by Maurizio Trevisan, M.D., using data from the 1960 Buffalo Blood
Pressure Study. Results of the research
were published in the ovember-December issue of Psychosomatic Medicine.
To assess the effect of social interaction on blood pressure, researchers selected five categories of social encounters - household size, number of siblings, participation in social clubs and
meetings, religious service attendance
and maritalstatus-andcompared them
with adjusted mean blood pressure levels for the 656 men and 753 women in
the study group.
Among women, the only category that
showed a significant relationship to blood
pressure was number of siblings. Those
with six or more brothers and sisters had
significantly lower blood pressure than
those having five or less. Among men,
significant correlations with blood pressure showed up only with size of household - the larger the better - and club
participation - the more active the better.
The researchers were surprised to find
no significant relationship between blood
pressure and church attendance since
other research has shown an asso~iation
between attendance at religious services
and longer life, less hypertension and
better health in at least some segments of
the populations studied.
+
By

SCIENTIST

LOIS

BAKER

SPRING

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�. ... ........ . .... . ........... .. ..... .. .... . ... . . . ......... . .... . ........ . ...... . .

Money more important in
motivation to stop smoking

quit smoking and 13 had not.
The smokers listed lack of will power,
having nothing to do with their hands and
nervousness as the most important rea+
sons for resuming their habits.

mokers who quit smoking after
bypass surgery considered saving
money, not improving their health,
the most important reason for kicking the habit, researchers in the
University at Buffalo School of
Nursing have discovered.
And patients who returned to smoking
did so within the first three months, they
reported
in an article in
the Journal
of
Cardiopu l m onary RehabilitaLion.
The
survey of 46 people taken five years after
surgery to determine the perceived benefits and barriers to stopping smoking
showed that being more healthy wasn't
even the second most important reason
for remaining smoke-free. "Feeling better
emotionally" (no smoker's guilt) held that
position.
one of the other potential benefitsfreer breathing, less coughing, feeling better physically- were listed often enough
to be statistically significant. Further, the
severity of their disease had no effect on
p·atients' smoking behavior after the operation.
Thestudytracked 197 patients who had
coronary bypass surgery at Buffalo General Hospital in 1985. Of that group, 112
were smokers when they entered the hospital. All participated in post-operative
programs to help them stop.
The smokers' group was resurveyed after five years to find out how many were
still smoking and why. Of the 46 who
returned the survey, 33 had successfully
BUFFAL

O

PHYSI

C

IAN

By

LOIS

BAKER

Roswell Pen to concUt
Plme II breast aner study
oswell Park Cancer Institute will
conduct a Phase ll clinical trial of
liposome-encapsulateddoxorubicin
(TLC D-99) to treat women with
advanced breast cancer who have
not had prior chemotherapy.
Doxorubicin is a widely used anticancer
drug that has proven effective in treating
solid tumors- carcinomas of the breast,
lung and bladder-as
well as lymphomas ,
leukemias and soft tissue sarcomas. Although effective, doxorubicin has been limited by the side effects
it can cause, particularly damage to the
heart, which may be
irreversible and can be
fatal.
"Since the first chemotherapeutic agents
were introduced," according to Ellis Levine,
M.D. , assistant professor of medicine and the
principal investigator
of the study, "their inability to differentiate
between malignant
cells and healthy cells
has resulted in potentially life-threatening
side effects that have
limited the dose that
A

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[I]

could be safely given to patients."
Encapsulating the chemotherapeutic
agent could reduce its toxicity and target
the drug to the tumor, according to Patrick
j. Creaven, M.D., Ph.D. , associate research
professor, who was among the investigators completing Phase l clinical trials of
TLC D-99 in 1990. Those trials demonstrated that the toxicity of doxorubicin
was reduced to a point where it may be
possible to expand its use.
When TLC D-99 is administered, its liposomal structures shields the body against
many of the toxicities of the enclosed doxorubicin. lt is thought that TLC D-99 accumulates at the sites of tumors and avoids damaging tissue. The liposome breaks down after it
reaches the targeted sites and releases the
+
doxorubicin.

I

IENTIST

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· · · · · · · · · · · · · · · · · · · · · · · · · · · · · · · · · · · · · · · · · · · · · · · · · · · · · · · · · · · · · · ·· · · · · · · · · · · · · · · · · · · · · · · · · ·

~

BuHmo Genetd flies pm1 i1

study to cid stroke victins

issue plasminogen activator, tPA, the clot-dissolving agent that
provides hope [or many heart attack victims, is now being studied at The Buffalo General Hospital for its effectiveness in offering
similar results for stroke patients.
Buffalo General is one of l3 facilities
nationwide involved in the study to determine if t-PA can increase recovery
chances for stroke patients. The purpose of the study is to investigate whether
t-PA can improve recovery by opening
blocked arteries from strokes caused by
a clot in an artery leading to the brain.
"The use of agents like t-PA in acute
stroke represents a new exciting chapter
in stroke therapy," said Patrick Pullicino,
M.D. , UB assistant professor of neurology and chief neurologist for the local

0

BUFFALO

PHYSICIAN

arm of the
study. "Until
now , there has
been no effective therapy for
a stroke. T -PA
promises to be
the first drug
that will reduce
the
amount
of
brain damage
caused by a
stroke. "
To be effective, t-PA must
be administered within
six hours of the
onset of stroke
symptoms.
Pullicino
emphasized
doctors' attitudes about
stroke, as well as those of the general
public, would have to change if drugs
like t-PA are to be useful. "The lack of
treatment for stroke in the past has meant
a pessimistic attitude and usually a long
delay from the time of stroke onset to the
time of arrival at the hospital. "
The first BGH patients in the study,
sponsored by the California pharmaceutical firm , Genentech, have experienced
positive results [rom the drug.
+

clothing items to first-time pregnant teenagers who receive regular checkups
through the Prenatal Care Assistance
Program (PCAP) or are in Medicaid assistance in the Sisters Hospital Outpatient Program. PCAP provides free prenatal care to women who have no health
insurance.
The new program provides a "credit"
each time the patient visits the prenatal
clinic at Sisters for her scheduled
checkup. After eight visits, she qualifies
to receive a layette package that includes
a variety of baby clothing items, receiving blankets and a specially designed
diaper bag.
+

VA Medical Center one of
14 to receive HUMOR
Proiect grant

he Buffalo VA Medical Center has
been awarded a grant to establish
a Humor Resource Center within
the medical center
The grant, awarded by the HUMOR Project in Saratoga Springs,
New York, was one of 14 awarded nationwide from a total of over 100 applicants. According to Michael Ackerman,
R.N. , Ph.D. , director of the medical
center's grant-writing team , "The Humor Resource Center is part of a larger
project at the VA aimed at instilling a
sense of humor into the health care
setting. These are very difficult times for
health care centers, and we feel that by
providing an avenue for humor and creativity , there can only be one benefit and
that is improved patient care."
An integral part of the program is the
isters Hospital has begun a pro- use of a hospital-wide humor cart,
gram to offer incentives for first- dubbed "The Chuckle Wagon, " which
time pregnant teenagers to seek will make a variety of items, including
prenatal care.
books, videotapes , toys, puzzles, etc.,
Called "New Beginnings," the available to patients throughout the
program provides basic infant medical center.
+

Sisters Hospital program
offers incentives for early
prenatal care

AND

BIOMEDICAL

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�. .. . . . . . . . . . . . . ... . . .... . . . . . . .. . ... ..... . . . . .... . [1]
CHOB purchases area's first
fully computerized obstetric
management system

ultrafast CT scanner - an !matron can screen for coronary artery disease by
detecting calcifications in the arteries
associated with atherosclerotic plaques.
Imatron scanners are ultrafast, taking
images in one-tenth of a second as opposed to the two seconds required for
conventional CT imaging. Because it is
so fast, !matron scanning freezes the
action of the heart's beat, resulting in
clear, precise images that show calcifications. Images taken by traditional CT
scanning can be blurry.
Studies have shown that when I matron
scans show no calcification , the patient
is free of coronary artery disease. The
presence of calcifications, however, may
indicate the presence of CAD.
According to Alan S. Brody, M.D.,
director of the CT Section of the Department of Radiology at Children's and

he Children's Hospital of Buffalo
has become the first area hospital to
offer a fully computerized obstetrical management system in its labor
and delivery suites.
Purchased with proceeds from
its 1990 and 1991 Golf Classic, the
hospital's new system provides the staff
with vital information on both the maternity patient and her
::~ -~-=-=-=
. ./ '_...,.- ~- . .~....ro&lt;t"·-··-:'' baby. From a central
station, the system allows ll patients to be
monitored at the same time on a single
screen display, providing an instant overview of each patient in the system with
immediate warning of critical conditions.
The hospital, the region's designated
high-risk maternity center with 5,000 deliveries annually, also purchased a new
technologically advanced ultrasound for
labor and delivery.
Lawrence Romano, chairman of the '91
Golf Classic, notes "The new computerized monitoring system will enable the
hospital to continue offering the highest
quality care to maternity patients throughout Western New York. The Golf Committee is very proud of the business
community's commitment and support of
Children's Hospital. "
+

assistant professor of radiology at UB ,
"The Imatron has probably had the very
best results in early evaluation of coronary artery disease than anything that's
been tried previously.
"The !matron scan is a screening test.
If the Imatron shows that you have calcifications, it doesn 't always mean that
you have coronary artery disease; but if
the I matron shows no calcifications, you
do not have CAD. In cases where no
calcifications are present, an invasive
angiogram should not be necessary. "
Brody added, "Children's shares its
technology and expertise with the community. We have an adult medicine
department, and can cure adults as well
as children ."
In addition to being much faster than
traditional CT scanning, !matron scanning
uses a much lower dose of radiation.
+

ChUdren'sHospital
becomes first in state to
oHer ultrafast a scanning
he Children's Hospital of Buffalo
has become the only hospital in
ew York State to offer ultrafast
CT scanning.
Research being conducted nationally indicates that use of an
BUFFALO

PHYSICIAN

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'
The Robert L. Brown History of Medicine Collection
Housed in UB's Health Sciences Library, the Robert l. Brown
Robert l. Brown, M.D., medical school archivist and professor
History of Medicine Collection offers an unrivaled perspective
of medicine emeritus. The collection has grown, and continues
into the evolution of the art and practice of modem medicine.
to grow, in both scope and breadth with acquisitions and
From its pre-Civil War lithotomy instruments to its assortdonations each year.
ment of rare books dating back nearly half a millennium, the
The instruments collection includes a range of dental tools,
collection chronicles the progress of medicine
stethoscopes, surgical kits, bloodletting devices,
through the tools of its practitioners. One of
..-microscopes, lithotomy tools, obstetrical inonly three formal history of medicine collec- _,.__.,..~------- _:Struments, splints and early X-ray tubes. The
tions among medical schools in New York State,
oldest instrument - a Roman surgical clampthq:ollection at UB was formally established in
dates back to the first century A.D. In 1985,
1972.
Annette Cravens established the Edgar R.
Before that, it existed as an aggregation of
McGuire Historical Medical Instrument Fund
donations to the medical school and volumes
in honor of her father, a 1900 medical school
acquired for the school's library from 1846.
alumnus and chair of surgery from 1914 to his
One of the first donations was the 1 ,070-voldeath in 1931. The fund supports the purchase
ume private library ofUniversity founder james
of historical medical instruments.
Platt White, M.D. The medical school also
Here, The Buffalo Physician and Biomedical
acquired Roswell Park, M.D.'s entire 3,000Scientist presents a sampling of items from the
volume collection when he died in 1914.
Robert L. Brown History of Medicine CollecIn 1986, the collection was named after
tion.

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BUFFALO

PHYSICIAN

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�'A 19th century Staffordshire leech jar. cupping set and lancets. The practice of bloodletting reached a high point in

the early 19th century .

BUFFALO

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This Naval
surgical
kit . manufactured by

w. and H .
Hutchinson
of
Sheffield.
contains a
trephine.
tooth keys
and forceps. as
well as an

This Powell

amputation

and Lealand

saw and

"No. 1" stand

surgical

microscope.

knives. Gift

manufac-

of Theodore

tured in
England in
1884. represents the
height of
microscope
design and
craftsmanship in the
19th century .
Gift of William
H . Merrilees.
M.D.

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This un iden tified
art ifact was
made by
Maw and Ca.
of London . a
med ical
instrument
manufactu r er.

*

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A set of

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Lealand "No.
Humani

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Gravidi.

microscope.

originally

*

published in
1774. was
donated by
James Platt

..

White. M.D. It
is shown here
with early 19th
century
obstetrical
instruments.

*

This set of
dental
instruments
with ivory
handles (ca.
1850) is
similar to a
set made for
the Great
Exhibition of
1851. Gift of
L .L . Mulcahy.
Jr.. D .D.S.

*
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The staff of The Buffalo

Phys1nan and Bwmedical
Scientist gratefully
acknowledges collecuon
curator Lilli Sentz for her
mvaluable help m
producing this feature.

'A trephina-

tion set (ca .
1760). 'A
trephine was
a circular saw
used to
remove a
disc of bone

Post mortem

from the

instruments

skull.

(ca. 1870).

*

This set was
manufactured by Luer
in Paris.

*
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'A homeo-

pathic drug
kit. Founded
by Samuel
Hahnemann
in the early
19th century.
homeopathy
as a system
of medicine
was based
on the
doctrine that
diseases can
be cured by
administering
minute doses
of a drug
which in
larger
amounts
cause the
symptoms of
the disease.

*
BUFFALO

PHY

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AND

BI

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SCIENTIST

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I{}on't know
how I got
here, but I
couldn't
get up. I
wa\, pinned
to the asphalt
of Market
Street, my
legs were
moving but I
w~sn't going anywhere. ThiswasMarket Street in San
Francisco, so why
was the Empire
State Building looming in the horizon? It
was all so strange. Vice President Dan
Quayle was dressed in white culottes,
playing the accordian. It was more than I
could take. But as hard as I tried I couldn't
get up. Suddenly I could hear the beeping
of a dump truck backing up, heading right
for me .. The beeping got louder and more
piercing, and wouldn't stop. It was then
that I woke up.
I was in the Newborn Intensive Care
Unit call room, my first night "on," after
taking a four-year leave of absence to
perform standup comedy. I glanced at my
glow-in-the-dark watch (which retails for
$295, according to my father. He picked
it up for $39.95 and had the slashed sales
slip to prove it). It was 7:15 a.m. I
managed to sleep until 7:15 on my first
night, on call? I thought, "not bad" until
G)

BUFFALO

PHYSI

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I remember that I went to sleep at 6:45
a.m. Better call that number, see what's
the problem.
"Hello! This is Dr. Silver ...
"MEC!!! OR3!!!" CLICK!!
No good morning? MEC!!! What a
great medical euphemism. Makes me glad
I didn't become a plumber, which according to my father wasn't a "dignified job."
You spend your life up to your elbows in
... 'mec!"'

Fortunately I don't have to get dressed.
I never intended to sleep. I just collapsed
in my scrubs and shoes.
So I just drag myself down the hall to
OR 3, wearing what amounts to pajamas
and slippers (no bathrobe, though). I'm
still waiting for the day when someone
will notice this and say, "Hey Stu, get out
of those pajamas and put on some clothes.
You're a doctor, for God's sake!"
Of course before you enter the hallowed ground of the OR, you must cover
your shoes with the "shoecovers." I must
admit that I was never quite sure whether
we do this to maintain sterile conditions
or to protect our shoes from falling "mec."
(Since surgeons and anesthesiologists
wear these covers and their showercaps in
the cafeteria, I've always assumed it was
for the latter.)
I must admit this was my first delivery
alone in a long time and I am quite nervous, but just like in comedy one must
"never let them see you sweat."
At least there aren't any hecklers, but I

AND

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OMEDICAL

I

of

Humor

still imagine the anesthesiologist yelling
from behind the drape.
"Hey Silverstein, YOU SUCK! " Where'd
you get your medical license from? A
raffle? Would you look at him intubate!
I'm waiting for Alfred Hitchcock to walk
through this scene!"
Relieved that this probably won't happen in a medical setting (with the possible
exception of quality assurance meetings) ,
I relax and enter the OR. I begin by
casually checking out the equipment on
the table as recommended by
NAl.Scourseand realize that some
things have indeed changed. The
NBICU nurse who will serve as
my assistant, informs me that
we are no longer required to"'
suck the meconium into our
masks through a Krazy Strawlike apparatus. It is now done with
wall suction.
Finally we've entered the "safe mec"
era in medicine.
The delivery goes well. I'm tempted to
say, "Thank you! Good night! Drive
home safely and don't forget to tip your
circulating nurses, they worked hard for
you tonight." Luckily, I keep this one to
myself.
BackintheNursery, l(;~~a:;;Zf£{jjd
it was the usual rounds:
"This is hospital day 4 forT win
A, who is now a five-cell morula, up
from two cells yesterday, tolerating
masked CPAP with good gases. Twin B

SCIENT

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�©

Stu

Silverstein,

M.D

.

..
is still a zygote and is dependent on hyperal.
He took in l20cc/kilo/day, urine output 2
cc/kilo/hour and a surprising three runs
batted in. "
The day was relatively uneventful except when the post call intern desaturated
into the '80s. Fortunately he came around
with vigorous stimulation and some bagging.
And so my final year of pediatric training was finally underway. Starting in the
NBICU was my choice; I figured it was one
of the tougher rotations, yet it was a "controlled environment," with a finite number of problems and finite number of
solutions. On day one, I
sounded like a veteran fielding questions from the
nurses. "OK, just turn the
ratedown,getagasandcall me
with the results. Yea, just go up
on the PIP and increase the rate and
get a gas ... " Oh! "Sorry, didn't
realize this was a bili baby. "
Ina way,standupdid prepare me
for this return appearance on
theresidencystage. Here,
too , we must
p e r -

BUFFA

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PHYSICIAN

Perform
procedures,
perform on rounds,
and, of course, perform for parents while
examining their children to show that we
take their concerns very seriously no matter how trivial they appear to us:
"Yes, I realize that your son has had
abdominal pain since birth, and I AM
concerned, however, since your child is
35 years old, I'm going to refer him to a
specialist. "
I did, indeed, learn some lessons in the
comedy world that would come in handy
here. I realize that rounds aren't "ExConvict Night" at the local comedy club,
and I won't be heckled by a cyanotic
mouth breather with no neck. However,
medicine does have its version of the
heckler and heckling, i.e. , the attending
and pimping.
I learned in comedy that one must
always be prepared for difficult situations
in advance. We comedians do this by
preparing what the unsuspecting audience perceives as "ad Jibs," i.e., if a couple
in their sixties should walk out while I'm
performing, I can't rely on luck. I must
allow them to get within five feetoftheexit
so everyone can see them and pause before
saying, "Mom! Dad! You promised that
THIS TIME you'd stay for the whole show! "
Likewise the performer, I mean resident, must be prepared with "ad Jibs" for
rounds. Standard comedian retorts like, "I
like the haircut, didn't realize Supercuts

AND

BIOMEDICAL

had a drive-thru window"
probably won't work on
rounds. Ad Jibs must be more subtle. For
example, when discussing the incidence
of various diseases, I bear in mind
"LaCombe's Rule of Percentages" (Hospital Physician, 1971, 7(2);102), whichstates
that the incidence of any disease is either
15 to 25 percent or 80 to 90 percent. Even
if I'm wrong, I'll be right if I finish my
answer with, "depending on the study. "
There are many others, however, since
I still have another six months to go and
some of my attendings might be reading
this, I will keep them to myself for now.
And so I am the comedian returning to
complete my medical training after starting and establishing my second career as a
standup comedian. I couldn't have done it
any other way. I feel the same toward
comedy that William Carlos Williams felt
toward poetry when asked how he reconciled such an unusual combination. They
both require an understanding of what
people are feeling and fearing in their
lives. In both cases it is my job to relieve
suffering, and in both medicine and comedy, timing is everything. And my time is
up. Thank you! Good night!
+
Stu Silverstein, M.D., president of Standup
Medicine Seminars of San Francisco, California , lectures nationwide on the role of
humor in medicine.

SCIENTIST

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•
•••
•
• • ••
• •••
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••

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�Roswell Park research team unravels the human oenome

Like a kaleidoscope, the Human Genome Project looks a little different to everyone _
who spends some time observing it. The view depends on the spin thats put on it.
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�o physicians and genetic counsel-

genes that, when altered through mutation, can cause disease. The lab has identified, among others on Chromosome 11,
the genes that cause aniridia, a form of
blindness resulting from a complete or
partial absence of the iris; Wilms' tumor;
diabetes, and albinism. Teams working on
other chromosomes have met with similar
success; a recent breakthrough was the
discovery, on Chromosome 7, of the gene
that causes cystic fibrosis.
The physical mapping is a tedious process of chemically breaking the DNA into
manageable pieces of 300,000 to 400,000
base pairs, then assembling the information into a continuous strand of information - a seemingly endless string of permutations of A, T, G and C.
But even success at this gargantuan
task, Shows says, will be only the beginning of understanding how genes work; it
won't mean that every genetic disease can
immediately be eliminated.
"It should not be construed that once
we know this sequence, this is the prescription of life," he says. "This is just the first
step in the long process of understanding
the information in the genome.
"How they function, how they are.controlled- all these are questions that have
to be taken up."
Because the Roswell Park lab has the
computer capabilities to maintain the physical map, Shows said, biologists - about
200 a year - often write to ask for help in
situating a gene they've extracted. The
Roswell Park researchers can analyze a
sample, match it against the DNA sequence
they've stored in the computer database
and tell the correspondent that the gene is
situated, say, in position l3 on the short
arm of Chromosome 11.
And so another bit of the human genome code is penciled in.
"Here's what I can picture," says Shows,
whose enthusiasm for the project is prodigious: "Once we get the physical map and
know what genes there are and know what
the characteristics of genes are, all of this
will be stored on computers. The time will
come when biology will be done sitting at
a terminal, instead of in the laboratory.
"The amountofinformation is astounding. After all, this genome we have sitting
here is the product of the universe."
Decoding that information doesn'tcome
cheaply. It now costs about $5 to pin down
each nucleotide base pair; if that figure

ors, the project is rich with promise for
endinghumanmiseryfromawiderange
ofgenetic diseases. To philosophers and
medical ethicists, it~fraught with perilous implications for social policy. To
pharmaceutical companies, it~ a potential bonanza ofgene therapies, a whole
new industry of genes as drugs.
The goal of the Human Genome Project, of nucleotide bases. The average chromohowever, is not complex: working in teams some contains 120 million base pairs; the
in laboratories throughout the United entire human genome contains 3 billion.
States, scientists are seeking to codify the
The project, begun in 1990 and expected
sequence of nucleotide "bases" that makes to cost U.S. taxpayers $3 billion by the end of
up the genes in each of the 23 chromosome its 15-year life, has been compared to taking a
pairs in the human body.
census ofeveryone on Earth -and getting all
The structure of the human genetic their addresses right.
code was discovered by James Watson and
About 2 percent of the total number of
Francis Crick in 1953 when they deter- human genes have been mapped thus far.
mined the configuration of the DNA (de"You could argue, why do this? " says
oxyribonucleic acid) molecule that is the Thomas B. Shows, Ph.D., an adjunct profundamental molecular unit of life. The fessor at the University at Buffalo School of
molecule is a double helix- shaped like a Medicine and Biomedical Sciences and diladder that is twisted. The sides of the rector of the genetics department at Roswell
ladder are composed of a sugar-phosphate- Park Cancer Institute. "But to me, it's out
sugar-phosphate polymer. The rungs are there to be understood. And what a thrill
made up of the four nucleotide bases it will be to understand the human getwo purines, adenine and guanine, and two nome. "
pyrimidines, cytosine and thymine. Each
Shows' 20-person lab at Roswell Park is
rung is formed by one purine and one involved in two aspects of genetic mappyrimidine; adenine always pairs with thy- ping. First is functional mapping - idenmine (A-T) , and guanine always pairs with tifying chromosome sites where diseasecytosine (G-C). Each side of the DNA related genes are located. He said the lab
ladder is complementary to the other.
has mapped about 400 genes- more than
The D A (about six feet of it) is located any other group in the world.
in the 46 chromosomes that are found in
And then there's physical mapping, the
the nucleus of every cell in the body. A primary goal of the Human Genome Project.
gene is a chromosome segment that con- Working with a computer database, the
tains specific genetic information, such as Roswell Park lab has concentrated its efeye color or the expression of certain dis- forts on the physical map of Chromosome
eases. The 23 chromosome pairs are esti- l l, which is estimated to contain 2,500
mated to contain 100,000 genes and each genes.
gene contains from 2,000 to 200,000 pairs
Chromosome 11, Shows says, is rich in

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doesn't fall to less than 50 cents per base
health care and health insurance; the
pair, the comprehensive project could be
• • effect of genetic testing on parent-child
doomed since the amount of money origirelationships .
nally allocated is not enough to decode all
"We're now moving into the area of
of the nucleotides at the present $5 per
insurance and insurability," Erbe says. "A
base pair cost. The Department of
lot of people are very concerned about
Energy and the ational Inemployment. But other than the
stitutes of Health, the major
occasional horrible case there
government sponsors of the
hasn't been much in the way of
project, are counting on developpre-employment screening yet."
ments in robotics and other technologiShows, at Roswell Park Cancer
cal improvements to make the process
Institute, says the concerns about ethical
cheaper before the money runs out.
• •
and social issues, although valid, are
Cost considerations aren't the only
• overestimated.
aspect of the Human Genome Project that
• "I get a lot of calls from ethicists and
• philosophers who want to know what's
has observers worrying. What about the
ethical and social implications of this newgoing to happen once the genome is
found knowledge? Like the design for a
sequenced," he says. "They're all connuclear weapon, the genetic code is somecerned that there's going to be a real probthing that, once discovered, can never be
lem quickly. We don't have a real problem
unlearned. The world will have to live with
quickly. We have a lot of work to do.
its effects.
"There will eventually be a blood test
Writers of science fiction and newspawhere your entire genome is analyzed. It
per "think pieces" have found much grist
won't be soon , but it will happen.
for speculation in the possibilities of the
"There's no question that my insurance
genome project:
company could look at that and, if I had
What will it mean for the insurance indussusceptibility to asbestos dust or whatever,
try, they ask, when it becomes possible to
they could decide I'm uninsurable. You bet
identify an apparently healthy person as carrythat's a genetic issue," Shows says.
ing the gene for a deadly disease?
"But to me, the ethical issues are not as
Who will have the right to study an
important as the risk/benefit ratio of getindividual's genome?
ting that physical map of the genome and
Can potential criminals be identified
discovering how to treat all those diseases. "
through a simple blood test?
What does the Human Genome Project
Will D A testing create a "genetic
mean for the practicing physician? Evenunderclass," shunned in their search for
tually, it may make all the difference. In a
jobs and health insurance?
book by Leon Jaroff, "The ew Genetics:
Richard W. Erbe, M.D., a UB medical they would abort a fetus if tests showed the The Human Genome Project and Its Imschool adjunct professor and director of baby would be born with CF.
pact on the Practice of Medicine," molecuthe Division of Genetics at The Children's
These parents' attitudes, they say in a lar biologist Leroy Hood is quoted as deHospital of Buffalo, knows the range of paper published in the May 1992 American scribing an exacting new world of doctorquestions that are being raised. For two journal of Human Genetics, may be indica- patient relations. After an analysis of a
years he has chaired the study group that tive of those of parents faced with similar patient's genome, he says, "the computer
reviews all grant applications for proposals choices about bearing children with other will give you a printout of the potential life
to study social-policy issues of the Human disorders.
history of that individual. ... You'll also get
Genome Project.
ElSI project proposals range widely in a printout that says, 'You should avoid
The project has allocated a generous 3 subject and originate both individually and overexposure to the sun, change your diet
percent of its budget to fund the study of jointly from theologians, scientists, actuar- at age 13, etc.' The focus of medicine,
the ethical, legal and social implications ies, historians and philosophers- groups basically, will be on keeping people well,
(ElSI) of its results. As a result, Erbe finds with little or no experience working with on making predictions about the difficulhis group in an unusual position: it has each other and often little or no knowledge ties people will run into and then avoiding
more money to fund research projects than of each others' fields. The concerns they those problems by manipulating their diet,
there are research projects to fund.
raise are just as diverse: such issues as their environment or their immune sys"In certain respects, the many real is- religious implications of genetic knowl- tems, or applying molecular pharmacolsues are no different for genetics now than edge; professional standards for the use of ogy."
Until then, we can only watch as the
they've been all along," Erbe says. "But D A typing in police work; the history of
now the public awareness is huge, because how people with genetic disorders have pieces of the human genome, one by one,
only one in seven of the fertile couples said been stigmatized; the problem of access to fall neatly and inexorably into place. +

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�IN AN 1\I'I'EMPT
TO LOOK
TIIEIR BEST,
MORE AND MORE
MEN ARE
UNDERGOING
COSMETIC SURGERY
THAN EVER BEFORE

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�lastic surgery, the equal opportunity operation, has come of age. Once the exclusive
domain of women, it is becoming more
and more popular among men as they flock
to surgeons in record numbers for chin implants, facelifts, eyelid tucks and liposuctions.
And although women still account for 90
percent of plastic surgeries performed, the increasing numbers of men who seek cosmetic surgery prove that women no longer have an exclusive
right to vanity.
After 17 years in the business, Hanley M. Horwitz, M.D.,
has witnessed a change in the type of
patients coming into his Williamsville
office seeking cosmetic surgery. Ten
years ago, he said, 2 percent of his
practice was male. Today men represent 33 percent of his patients.
What drives a man to seek cosmetic surgery?
"A very strong ego to start with,"
said Horwitz, a 1969 graduate of the
State University of ew York at Buffalo School ofMedicine and Biomedical Sciences. "And they can't be
easily embarrassed. They also must
have an overwhelming desire to have
something corrected."
Women also are important factors.
"Wives are significant," Horwitz
said, "very frequently young wives.
Men feel it's good for the relationship."
With society's intense focus on youth, there is no mistaking that this, too, plays an important role in their decision to
seek cosmetic surgery. But that influence, according to
Horwitz, is vastly overplayed.
"That's one way to look at it," he said, but overshadowing
this search for youth is simply the fact that people want to look
their best.
"Males age better than females," Horwitz said. "They don't
get those little crow's feet and spiders all over their faces
because their skin is thicker. And they don't get all the
wrinkles on their upper lip."
A man and woman walk into his office, both seeking a facelift.
"Most of the time, they don't need it. Most of the time, they
need something done with their eyelids" to achieve the results
they want, Horwitz explained, adding that most men are well

into their 50s, possibly their early 60s, before they need facelifts. Women, he said, usually need face-lifts 10 or 15 years
earlier in life than men , usually in their late 40s.
Buffalo surgeon and 1981 UB medical school graduate
Bruce J. Cusenz, M.D. , has noticed that in men seeking
cosmetic surgery, the aging process, regardless of the age, is
more advanced.
"Eyelids tend to hang more in men," he said.
jack Fisher, M.D., a 1962 UB medical school graduate and
professor of plastic surgery at the University of California, San
Diego, estimates lO to 15 percent of his patients are male.
"Many more men are coming in who feel fine , but look awful
with folds and bags of skin."
Not everyone who enters a plastic
surgeon's office ends up having surgery. Most surgeons have extensive
screening systems to weed out potential problem patients who have
unrealistic expectations about how
plastic surgery will change their lives.
Horwitz schedules three office visits for his patients before performing surgery.
"The first time I talk," he said.
"The second time I listen. I have to
flush the type of person he is out. If
he can't come in three times before
surgery, I won'tdo the surgery, even
if l'm doing a doctor- someone I
know well."
Based on the initial sessions, a good
portion of the problem patients are
weeded out. "If they had expectations beyond what I could do, I
won't even consider performing surgery," Horwitz said. For
men , he said, a frequent request is a face-lift that will help
them "to get their wife back or they want a job promotion,"

liON A MALE, YOU
WANT TO LEAVE
TH:E FEATURES ON
TH:E HEAVIER SIDE.
FULLNESS GIVES AN
IMPRESSION OF AUTH:ORI1Y, AND YOU
WANT TO LEAVE
SOME WRINKLES."

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he added.
Overall, the most frequent reason for turning someone
away is an unreasonable demand, like obese people wanting
liposuction to shed unwanted pounds. "They want to be
skinny," Horwitz said, "and you can't do that" with an obese
person through liposuction.
Enhancing the diagnostic techniques of some cosmetic
surgeons is computer imagery, where a patient can actually
visualize what he or she will look like after the surgery is
completed.
But Horwitz calls this method unfair.
"If you're showing it to the patients, you're potentially
implying a result. You're also giving them unrealistic expec-

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�tations. If you're using it to analyze things for yourself and not
showing it to the patient, you probably don't need it."
Horwitz further explained his aversion to the method.
"You can take away the bump on their nose with a
computer picture, but it isn't the way a nose is going to look,
because you'll have scar tissue and contracture. It's not going
to look like that anyway," he said.
Women on the whole don't experience as much dissatisfaction as men do after cosmetic surgery. Again , the selectivity of the surgeons comes into play, as those patients with
underlying psychological quirks are more apt to be dissatisfied.
As a rule, patient satisfaction with plastic surgery is quite
high, with more than half of Horwitz's patients returning for
more.
Both McKissack and Horwitz themselves have had eyelid
surgery and are pleased with the results. And both men said
they would have it again.
But gender is an important factor , as more women than
men seek further surgery.
"It's much more prevalent in women," Horwitz said.
"They have their eyelids done; a year goes by and their face is
sagging. It's not unrealistic that they would return for more.
"Men get something done, and they're done," he said.
The kinds of operations Horwitz performs on his men and

Bruce J. Cusenz

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women patients are basically the same - rhytidectomies
(face-lifts), rhytidectomies with liposuctions, rhinoplasties
-but the techniques employed on men and women differ.
"On a male, you want to leave the features on the heavier
side," he said. "Fullness gives an impression of authority, and
you want to leave some wrinkles. On a female you want more
of a sculptured look, and you want to remove every wrinkle."
Horwitz shares a philosophy held by many plastic surgeons: because of differences in skin thickness and texture,
and due to the increased presence of hair follicles, cosmetic
surgery on men can bring a worthwhile improvement. On
women the results can be spectacular.
According to PaulK. McKissack, M.D., a '56 graduate of
the University at Buffalo medical school, men are not as good
candidates for plastic surgery as women, especially when it
comes to facial surgery.
"Men's facial skin is a lot thicker than women's because it's
hair-bearing," he said. "They also have a stormier course
because they bleed more" due to the increased vascularity of
the hair-bearing skin, he added, explaining that because of
this, control of blood pressure is particularly important in
surgery on men.
"Women are easier to do," he said. "Their bones aren't
[hard] like marble."
Men also pose challenges when it comes to hair placement
and concealing scars. For example, a face-lift on a male
could cause his hairline to
migrate behind his ear. To
avoid this, hair follicles are
destroyed in some cases. Doctors point out that on men it is
much more difficult to conceal scars after surgery because
they don't wear makeup.
Nose surgery differs among
men and women, too. "If you
overdo it on a man, you can
make him look effeminate,"
McKissack said.
Surgeons also cite personality glitches as another source
of complication in male cosmetic surgery.
"Men are impatient," said
james Wells, M.D., chairman
of the public education committee for the American Society of Plastic and Reconstructive Surgeons. "And from that

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�Hanley M. Horowitz
and female patients.
"Men come in just as tentative as the women, and they take
a little more time beating around the bush. It takes them
longer to open up," Cusenz said, "but once they get going ... "
McKissock, who practices in the Los Angeles suburb of
Torrance, California, has experienced a marked increase in
face-lifts among his male patients. "It used to be considered
a feminine operation," he said, "but especially here in Los
Angeles, it's quite common."
Some procedures, McKissack added, such as pectoral
implants for men, are a very small and insignificant pan of
plastic surgery. They appeal, he said, to "a certain type of
man," such as the body-builder type.
"I wouldn't even know who to send a patient to who
wanted them . It's a stupid operation," McKissack said. It's a
fly-by-night thing, and it will come and go along with a lot of
other dumb things because they're a male fad ."
"It's frivolous, " he said, "and for a plastic surgeon to call
something frivolous .. . but this really is."
+

standpoint, they are more difficult to deal with than women.
"Women are much more attuned to the length of time it
takes to recover. Men think they are indispensable," he said.
"Before they get out of the recovery area, they have a phone
screwed into their ear. "
Horwitz described his typical male candidate as a business
executive with limited time.
"They look at it like this: 'I want to buy a new car. I want
to buy a new suit. I want to have my eyes done.' It's just one
of many things."
And before surgery, Horwitz, said, men are more demanding.
"The male comes in and says: 'I have three days off and I
want this done.' I say, 'But it isn't what you need.' If he still
wants it done, I won't do it.
"The female comes in and says: Just do anything you can;
I want to look better."'
When the surgery is completed, Horwitz added, "males are
the most cooperative and the least demanding."
By contrast, Cusenz sees few differences between his male

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~
I

UB medical school ranks
high in terms of minority
graduates

years."
Many of the programs for minority
students - such as the Federal Health
Centers Opportunity Program, the Minority High School Student Research
Apprentice Program and the summer
enrichment programs - have been
funded by grants received by Wright. +

nderrepresented minority students represent a higher percentage of graduates of the School of
Medicine and Biomedical SciB Y
M ARY
B ETH
S PINA
ences than at medical schools at
Medical students learn how to set up a private or
other public universities in ew
group practice at UB' s Prep for Practice program.
York, according to a survey conducted
dents some sort of benchmark from
by the American Association of Medical
which to make decisions about things
Colleges. The medical school ranked
like where to geographically set up a
16th in the survey of the 126 accredited
practice or buy into one, what some of
medical schools in the U.S. Cornell
raduating medical residents the facility requirements are for differUniversity's medical school, ranked
have rarely received sound ent kinds of practices and how best to
ninth, was the only one in New York
practical management training handle their own personnel," Richert
ranked higher.
in
how to set up a private or added.
The survey showed that students in
The program attempted to give resigroup practice once they leave
this group made up 12.2 percent of the
their residencies. But a new dents further options concerning join704 students graduating from the school
from 1986 to 1990. During the period, program at UB, called Prep for Practice, ing an HMO as well , he said. "For
the University at Buffalo medical school is helping to change that, according to example, a doctor doesn't have to worry
graduated 86 students in the john Richert, associate dean for alumni about getting malpractice insurance if
underrepresented category, consisting of relations in the School of Medicine and he works for an HMO. He's already
covered. And he receives a guaranteed
African Americans, mainland Puerto Biomedical Sciences.
salary.
I think it's important for a young
"We've long been wanting to do someRicans, American Indians and Mexican
thing for graduating residents. It's really physician to understand these types of
Americans.
Maggie S. Wright, Ph.D., assistant long overdue," he explained. "This pro- things."
Richert gave an example of how imdean of student affairs, attributed UB's gram touches on things that are never
outstanding ranking to a number of fac- taught in medical school about what it portant geographic placement of a pracmeans to begin a practice. This program tice is by pointing out that if a young
tors.
is
practical preparation for someone doctor chose to begin a general practice
"For the past decade," she said, "we
who's
not going into academic medi- near the site of a military base, where
have built and maintained a highly succine.
"
most of the people in the community
cessful and comprehensive pipeline for
Richert said that the program, which would already be cared for by the base
early identification of talented minority
students in Western New York and en- took place last November at UB and was doctors, the new practice would unrichment programs for middle and high sponsored by the Medical Alumni Asso- doubtedly fail. "These young doctors
school students as well as undergraduate ciation, is designed to help graduating want to be able to make a living. I think
and pre-med and accepted medical stu- residents make intelligent decisions this program teaches them and also takes
about criteria such as malpractice insur- some of the pressure off by giving them
dents."
Wright noted that "faculty have par- ance, establishing a market for a prac- options."
While practical knowledge was
ticipated in summer minority research tice, banking and financing and risk manprograms at the school and have been agement. It was a single-day, eight-hour stressed during the program, Richert
extremely enthusiastic and cooperative seminar. "We (Medical Alumni Asso- said that another purpose of the seminar
in working with minority student en- ciation) were working in concert with was to present a myriad of possibilities
richment programs and projects over the Syntax Laboratories. It gave the resi- to the residents from which they could

Prep for Practice
program helps residents
set up new practices

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make decisions based upon their own
needs and wants. "Do you want to
practice alone? Do you have the start-up
costs involved in a solo practice7 Or is
an HMO the best way to begin? And
where do you want to live? These are all
important questions, " he said.
Ninety residents attended the inaugural seminar last fall and there was
nothing but praise for the program, according to Richert. "It really was a
smashing success. All of the evaluations
were very positive. lthink that anybody
who wants to go into some son of private, non-academic practice should be
exposed to a program like this before
leaving medical school. "
+
-BY

MARK

HAMMER

UB to estabHsh nation's
first comprehensive nuclear
imaging training center
he State University of New York
at Buffalo will establish the first
comprehensive training center for
nuclear imaging in the United
States, funded by a three-year
grant from Siemens H.G.
The grant is the result of two years of
discussions between UB and Siemens.
The training center, to be headquartered in the Department of uclear Medicine, will concentrate on positive emission tomography.
"We're in the process of organizing a
core curriculum to train everyone from
the PET technician who assists the chemists, through all of the higher levels of
science right up to a director of PET
operations," said JosephA. Prezio , M.D. ,
UB chair of nuclear medicine. " o one
is doing that anywhere in the United
States. "
Siemens needed a center that could
train its people in depth in this new

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field, Prezio said, and UB already had a
well-regarded program in nuclear medicine and is establishing a major PET
facility. The University , in conjunction
with the Buffalo VA Medical Center,
will be operating one of the most advanced PET imaging centers in the world
by 1993.
"The problem throughout the U.S. ,
and probably the world, is that training
for PET has not been organized
appropriately, or in enough depth , so
that you can send someone to one site
and have them come back seasoned
and trained, " Prezio said. "Our goal from
the beginning," he added , "in addition
to establishing the PET imaging center
for research and clinical use, was to set
up a national educational program that
would be unrivaled in the United
States. "
The center will be organized around
four major training groups - technicians, radiochemists, nuclear physicists
and physicians. Training of PET technicians will begin this spring. Other programs will accept enrollees as the
curriculum is finalized. Training periods will vary from a month for technicians to two years for physicians being
trained to interpret PET images.
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Ri(hard Safeer, right, distusses his poster with
Murray Murphy at the Researth Forum.

AND

BIOMEDICAL

Congratulations to the
winners of the 11 th annual
Student Research Forum
irst Honors Winners
Richard Safeer: The effect of the
"Get Heart Smart" curriculum on
middle school students.
Diana Sanderson: Urine sorbitol
excretion reflects blood glucose
level in diabetes mellitus.
Second Honors Winners
Keung Lee: Characterization of a eDNA
clone that encodes a Schistosoma mansoni
antigen that may play a role in immunity.
Harold Lilt: An integrated physician
workstation: Digital patient records and
the medical desktop.
Atif Zafar: The temporal dynamics of
scoliosis: Visualization of spinal geometry.
Ann Comi: Copper toxicity and the distribution of copper in normal and
Menkes lymphoblasts.
Third Honors Winners
Shane Ferguson: A controlled comparison of four different surfactant preparations in surfactant-deficient preterm
lambs.
Andrew Michel and Myron Glick: Cardiovascular risk factor
analysis of an old order Mennonite community.
Gina Marrero: Effect of
combination photochemotherapy and
hyperthermia vs. rotenone on human squamous carcinoma.
Kristine Tenebruso:
~ Knowledge, attitudes
~I and practices of
:= women over age 50
regarding breast cancer screening and
breast cancer screening practices.
+

SCIENTIST

SF&gt;RING

I

9

9

2.

ED

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[1]
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American Board of Pediatrics and its
sub-board of pediatric nephrology. He
is a diplomate of the American Board of
Medical Examiners and a member of the
American Pediatric Society and the executive councils of the American Society
of Pediatric Nephrology and the Eastern
Society for Pediatric Research.
+

Children's Hospital appoints
Alon Co_ppens to Department of Radiology

T

he Children's Hospital of Buffalo
has appointed Alon Coppens,
M.D. , to a fellowship in its Department of Radiology.
Coppens received his medical
degree from the State University of New
York at Buffalo School of Medicine and
Biomedical Sciences. He received
his postgraduate
medical training at
Mary
Imogene
Bassett Hospital in
Cooperstown, New
York, and completed his residency
in diagnostic radiology at the University
of Arizona School of Medicine.
+

-BY

.
F

Bruder Stapleton, M.D. , A. Conger
Goodyear professor and chair of the
Department of Pediatrics, has been
appointed by the executive board of
the American Academy of Pediatrics to the academy's Council on Pediatric Research.
Stapleton is also pediatrician-in-chief
at The Children's Hospital of Buffalo.
The Council on Pediatric Research
was established to provide a forum on
pediatric research; its objectives include
promoting pediatric research through
the identification of major researchable
questions, recognition of important completed pediatric research and the development of statements or other publications on pediatric research.
Stapleton, a fellow of the American
Academy of Pediatrics, is certified by the

BUFFALO

PHYSI

C

PAGE

Raghavan appointed
division hea~ at Roswell
Park Cancer Institute

D

Stapleton ap~ointed to
councU on peCiiatric research

6)

ARTHUR

IAN

erek Raghavan , M.D. , Ph.D. , has
been appointed professor of medicine at UB and chief of the divisions of solid tumor oncology
and investigational therapeutics
in the Department ofMedicine at Roswell
Park Cancer Institute.
Raghavan earned his medical degree
from the University of Sydney, Australia, and his doctoral degree in experimental pathology from the University of
London, England. He completed his
residency in general medicine at the
Royal Prince Alfred Hospital and served
a medical oncology fellowship at the
Royal Marsden Hospital, Ludwig Institute for Cancer Research, Surrey, England , and a research fellowship in medical and urologic oncology at the University of Minnesota.
Prior to taking the position at Roswell,
Raghavan served as senior medical
oncologist as well as research director of
the Urological Cancer Research Unit,
Royal Prince Alfred Hospital, Sydney,
Australia.
Raghavan has published over 150 articles in peer-reviewed journals and presented over 100 papers at national and
international meetings. He serves on the
editorial board of the journals The Prostate, The Breast and The European journal of Cancer.
+

AND

BI

O

MEDICAL

Head of rehabilitation
medicine named at BGH

G

ary S. Clark, M.D ., a UB associate professor of rehabilitation
medicine , has been appointed
head of the Department of Rehabilitation Medicine at Buffalo
General Hospital.
Clark earned his medical degree at
jefferson Medical College, Philadelphia,
through a five-year premedicaVmedical
accelerated program with Pennsylvania
State University. He is a diplomate of the
American Board of Electrodiagnostic
Medicine. Most recently, he served as
medical director of Rehabilitation Services at Park Ridge Hospital, Rochester.
A fellow of the American Academy of
Physical Medicine and Rehabilitation, Clark
is also a member of the board of trustees of
the Association of Academic Physiatrists.+

Chddren'sHospital names
attending physician in
otolaryngology department

T

he Children's Hospital of Buffalo
hasnamedMichaelP. Pizzuto, M.D. ,
to the Department of Otolaryngology as an attending physician.
Pizzuto will manage all aspects
of pediatric otolaryngology with special
interest in pediatric airway and voice.
After receiving his medical degree
from the State University of New York
Upstate Medical Center, Pizzuto completed a residency in otorhinolaryngology at the UB Graduate Medical!Dental Education Consortium. He completed
a fellowship in pediatric otolaryngology
at Children's Hospital of Michigan.
Pizzuto is a member of the American
Board of Otolaryngology, Head and Neck
Surgery and the American Medical Association.
+

SCIENTIST

SPRING

1992

�·········· · ················· ···· ·························· · ······························ •

1

9

3

0

Hospital (Co rnell University

5

Medical College).

WILLARD G . FISCHER'36, fully re-

SEBASTIAN CONT I '70 ,

cine on July 1, 1991, after 54
years.

9

4

0

9

ROBERT

8
J.

0

5

BRACO '80,

an-

nounces that he is beginning a

tired from the practice of medi-

1

1

5

has a

private practice in vascular sur-

new practice in occupational and
environmental medicine in

gery in Sacramento, California,

Appleton, Wisconsin. Braco re-

and is an associate clinical pro-

ceived his M.P.H. in 1990.

fessor at the University of Cali-

JOHN D . WHITE '40, is serving on

fornia at Davis.

R ICHARD

A.

SMI T H '81 ,

has

the boards of the Older Americans Council and the AARP in

ELLIOTT BRENDER '70 ,

is as-

moved to Boston (Jamaica Plain),
Massachusetts, to become an at-

Tavernier, Florida.

sistant clinical professor in sur-

tending pathologist at the

gery at the University of Califor-

Faulkner Hospital.

FRANK

A.

PFALZER '46 ,

has

David H. Nichols '47

nia at Irvine, and chief of surgery

been retired since july 1989. He

1

9

6

0

5

at Garden Grove Hospital, Gar-

HOWARD WALDMAN '81 ,

den Grove, California.

his wife,jan, announce the birth
of t h eir daughter, Alanna

and

now lives at 2 Laurel Oak, Amelia
Island, Florida, and spends sum-

ROBERTA M . GILBERT ' 62 ,

mers in Western

Falls Church, Virginia, informs

RETA D . FLOYD'73, announces

Denbrook,onSeptember9, 1991.

us that her book, "Extraordinary

the opening of her new office for

Waldman is director of the car-

Relationships, A New Way of

the practice of psychiatry at 924
Buena Vista, Duarte, California

diac catheterization lab at Salem

ew York and

Muskoka, Canada.
DAVID H . NICHOLS '47 ,

has

of

accepted an appointment as Vis-

Thinking About Human Connectedness," will be published in

iting Professor of Obstetrics, Gy-

June 1992.

Hospital.

91010.
D O U G LA S
MELVIN R . PRATTER '73 ,

necology and Reproductive Biol-

is

AN D

PLESKOW '82 ,

RANDI

announce that

ogy at Harvard University School

JEFFREY

of

head of the division of pulmo-

Rebecca Danielle, born on Sep-

of Medicine and Head of the Di-

Brewester, New York, writes, "1

vision of Gynecologic Pelvic Surgery at the Massachusetts Gen-

have achieved no positions of
prominence, written no notewor-

nary and critical care at the Robert Wood johnson School of
Medicine, Camden, ew Jersey.

tember 10,1991, has joined her
sisters Sara, 5, and Heather, 2 V2.

eral Hospital.

thy medical articles and am di-

S.

CARR

' 64 ,

vorced. 1 am very happy. "

1

9

5

0

5
JOHN J . BIRD ' 65 , ofWilmette,

BERNARD H . SKLAR ' 56 ,

Fair Lawn,

of

ew Jersey, retired

from active practice October 31,

lllinois, is an associate professor
of ophthalmology at

orthwest-

ern University.

1991.
ROSS E . MCRONALD ' 66 ,
BEN CELNIKER ' 56

and his

wife, Ilene, announce the birth of

was

medicine at Rutgers University.

1

9

7

0

his wife Debbie have five chil-

Community Hospital of

Shore University in Lattingtown,

li na, School of Medicine.

of directors of the American Lung

of

D E NNI S L. B O RDAN '70 ,

was elected vice president of the
board of directors of the Ameri-

Port Washington , New York, was
recently named associate chair-

can Diabetes Association , Western ew York Chapter.

man of the department of surgery at North Shore University

PHYSICIAN

A

N

D

orth

New York.
R ICHARD L . C OLLINS '83 ,

has

recently been elected to the board
Association of Western New

DAVID M . K E NTON '79 ,

and

their second child, Michael An5

is a vas-

cular surgeon at Glen Cove's

dren ages 15, 14, 13, 12 and 6.
Neuberg is an associate professorof pediatrics in the division of
pediatric hematology-oncology
at the University of South Caro-

his wife announce the birth of

CHARLES F . O ' CONNO R ' 57 ,

BuFFALO

and

recently named director of sports

their son,Jared Brandon, on November 17, 1991.

G E RARD VI T A LE '82 ,
RON W . NEU BE R G '77 ,

drew, on September 3, 1991.
Kenton is a practicing cardiologist in Deerfield Beach, Florida.

BIOMEDICAL

York. Collins also recently joined
Buffalo Medical Group.
R E NATA WAJ S MAN '83 , writes,

"We have just returned to the
USA after spending a year and a
half in Israel. Ourfirstson, Oren
Sharabi, was born in Israel in

SCIENTIST

SPRING

1

9

9

2

til

�••

........................................................................................

OBITUARIES

July 1991. I am now joining a

V I NCEN T J . FASANEL LO '86 ,

group in Cainsville, Florida, in

and his wife Donna proudly an-

gastroenterology."

nounce the birth of their son,

died December 26, 1991 in St.

Vincent John , on February 3,

Paul , Minnesota.

ROBERT

LASEK

' 84 ,

and

COLETT E ( PRUEFE R ) LASEK
'84 ,

announce the birth of their

BRINA KESSEL RICHTER ' 25 ,

1992. Fasanello is a psychiatrist
with Westfall Associates in Roch-

JOHN J . CONNELLY '42 ,

ester,

January 3, 1992, in Buffalo , New

ew York.

first child, Christopher Ryan
Lasek, on December 10, 1991.

died

York.
SANFORD LEVY '86 ,

writes,

"After travelling the world for

GEORGE J . ALKER , JR. , ' 56 ,

LINDA PETERSON MANDANAS

two years, I have settled back in

former chair of the Department

was recently inducted as a

Buffalo and have joined the Cleve-

of Radiology, died December 31,

fellow of the American Academy

land Hill Medical Group, prac-

of Family Practice at the annual

ticing internal medicine."

'84 ,

AAFP meeting in Washington ,
ART H UR WE ISSMAN '86 ,

D.C.
GRACIELA

has

1991 , in his home in Williams-

George J. Alker, Jr., 'S6,

ville, New York , following a

burgh as assistant professor of

lengthy illness. He was 62.

radiation oncology.

Alker, who worked actively to

joined a private practice in gen-

promote passage of

( CONSTANTIN O)

era]surgeryinBuffa]o, ewYork,

State's mandatory seat belt law,

writes, "jim

with jonathan Reynhout '68.

DESEMONE ' 85 ,

1

9

9

0

HEIDI DEBLOCK

s

'90 , and her

and I have recentl y moved to the

Weissman 's

Berkshire, Massachuseus, area,

Zachary Arthur, was born on

husband announce the birth of

but more importantly, our daugh-

April 12, 1991.

Elizabeth Wende DeBlock on

second

child,

February 2, 1992.

ter, Marcela Grace, was born SepJOHN

tember 8, 1991. "

E.

ZVIJAC '86 ,

com-

pleted an orthopaedic surgery
of

residency at the University of

Norfolk, Virginia, has started a

Miami's jackson Memorial Hos-

plastic and reconstructive sur-

pital in june 1991. He is cur-

gery fellowship at Eastern Vir-

rently doing a one-year fellow-

ginia Medical School.

ship in sports medicine at the

MICHAEL JON DENK '86 ,

American Sports Medicine InstiANDREW GIACOBBE '86 ,

of

tute in Birmingham, Alabama.

was honored by Governor Mario
Cuomo two years ago for his
service on the Governor's Coalition on Traffic Safety.
Alkerwas chair of the Department of Radiology from 1981
until he retired in September
1991. During the same period,
he served as director of the Department of Radiology at Erie
County Medical Center, where
he was a neuroradiologist from
1963 until his retirement.
He was honored last year as

Richmond, Virginia, writes, "My
wife, Laura, and I became the
proud parents of our new baby

ROBERT F . CAFARELL

'87 ,

writes, "I have combined an aca-

daughter, Cristina Maria, on No-

demic practice in anesthesiology

vember 20, 1991." Giacobbe is

at the University of Rochester's

currently a plastic surgery fellow

Strong Memorial Hospital with

at the Medical College ofVirginia.

ew York

Physician of the Year by Erie
County and ECMC.

private practice at Rochester General. My wife, Brenda, and I are

DEIDRE GREENE '86 , of Allen-

town, Pennsylvania , writes, "My

expecting our first child in March
1992."

husband, Rob Dixon , and I are
thrilled to write of the birth of

RUS S ELL FUHRER ' 87 ,

mar-

our second child, a daughter,

ried Nancy in January and has

Aurora, born August 8, 1991."

joined the University of Pius-

ti)

BUFFALO

PHYSICIAN

A

N

0

BtOMEOICAL

SCIENTIST

SPRING

1

9

9

2

��BUFFALO PHYSICIAN AND BIOMEDICAL SCIENTIST
STATE UNIVERSITY OF NEW YORK AT BUFFALO
3435 MAIN STREET
BUFFALO NEW YORK 14214

ADDRESS CORRECTION REQUESTED

Non-Profit Org .
U.S. Postage
PAID
Buffalo, NY
Permit No. 311

�</text>
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                <text>Copyright 1992 University at Buffalo, State University of New York </text>
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                    <text>�THE BUFFALO PHYSICIAN
AND BIOMEDICAL SCIENTIST
\c umc 2~ "" mhcr l

r"'"'"'lld m the bst ts.sue of the P/1\~.n.:n that thl' propili&gt;Cd nC\\ research bu1ldmg was

DIRECTOR OF PUBUCATIONS

"lancv T

L ....

EDITOR
""~

rue

rr

m &gt;nt lolhg

r.: "'

ART DIRECTOR
A An I &amp;.cj:,' r

r "kcr

STATE; UNIV£RSITY OF NEW
YORK AT BUFFALO
&lt;;chool of !'.lrd•&lt;mr ~nd B•omrd~ral
~lfDCCS

Dr 1.&gt;!: 1 "'au~hton 'V
( hntc \I -'" f.'lr11r.

Prt

nt lor

EDITORIAL BOARD

Or J &gt;h
D
D~

Dr
Dr
M•
Dr
D
Dr

D

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r, l h
'd ru BrH hu
II rr I r r I)
Ra , 1td ~ ol I"
~- ~ JplcR
[' \ l
\ _ J [l nn-n
T1 &gt;th) '' bnrl
~olen

&lt;r

m !"'ot\\ 'tork C:.t..1tc o; buJgct Th(' offt tal grcundbreakmg a ma;L~r hLstoncal
t:Bovent'i I ~6-)C.UCXISI('n&lt;c \\.:sheldon 11.1ay.! IQQ1 Ihcfa~..tht) \\til pro' 1dc
nC\\, st.:tc or th(' an rusK rC'K'".trch l.tbor.non('&lt;; dcs1gned to be operated as a
. non-d('panmcnt.Jih ilSSt ncd untl It \\Ill al,o serve to umte the Health
as envtsioncd .Ls long ago ._, I CJ6l
""=--,....,....,.~,....;..-....,
fhe buildmg wtll straddl(' the "p&lt;:~e bel\\een the 'x.hool of Dental
Medion(' and th· rnrd•tal o;chool'" Am mal f .1oim AdJmmng the wcc;t
side of the lampu.:; \\ t'l beth(' clcgantllc.tlth C,Cicnce&lt;&gt; library and foster
Hall, the dental c;lhool"s b.L&gt;~c sctc.nlc fac1hty. On the ea.o.;t s1dc wtll be
the med1ca: sdtool complex Hamm.m (Old Nonon) Hall wtll be
rcnov.ard for the slhool c; .tdmmtstr.lllvc offu.:es later m th1s dcc.ade .md
w:r.nt:ltcd to 1hc new fa~.1ht) When completed Hamman \\ill be
bounded on each '&gt;ide by qu.tdr.mgles, and h) 1')&lt;)'), th(' campus w11l
1: \e ho•h pre• ntl' .md the l pacnv to conunuc lOntnhutmg toNe\\
York &lt;.t.!le'" needs,., bH.mied~t~l n.'sl'"ar~h The £acuity and I appreciate
L nt\t.T-.;ll\ admtnt ... tr.ttwn 'tl'~'r tl•est.:k slt..:Jcrshlpdnd the\\esteml\oew
,,..,, ........
,
m d1d on ou~ bdmlf Thanks
'tmccn:l\',
0

ASSOCIATE ART DIRECTOR
''-C"h 1 l"''ltrt f

and Supporters of the UB Medical School:

1

r.

~LJL-.~

a

&lt;I a 1.- '1

Jr.o
0• &lt; nl.- P • ~ I
Dr L uthc Rc ""'
D• Th&lt;'
P r'lthal
Dr ..,a t• .a ' u~•
D &lt;;trp r .,,,a ld n
Dr
&lt;.'It\ T r
X
Dr )ncmc ~at

John 'Iaughton. M.D.
far ( lmu:al Afjatr~
Dca'l, &lt;, h110l c( \ftd1une and BwmtdiCtJI ':lctrna•s
\ ltC Prt~tdtnt

rr

TEACHING HOSPITALS AND
LIAISONS
~· n u \ \ "tr , I ( cntr

L' flak• t.cncr I It&lt; i'' al
M chad ~"-""
flu I' o \ \ \1rJ I ( c " '

,,.,.u,emi, wheel comes round uga

rr...ula l'cdtt
( 1;, Jrrn, lie&lt; pi al

&lt;! u'i I&lt;
E nr ( o·ml\' \1cJ•c
( rntr•
Marv ft.trlflttl
\{&lt;!&lt;Y H&lt;&gt;Spll
M1l arJ ~, I re llr&gt;pll h
t r.,rrk ~a&gt;u
f&lt;os" rl
J k l 1
rr Ins 11 1
juduh ""
~· tr•• d &lt;t- ••II&gt; II&lt; p.t I
Otnnt)

\1 ( ''

Burr.·

\ddrcs~ t; t

In

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fl'c '' tr

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"'w hrk

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u

d suh

r ' em~ tr 1 ~ &gt; rhr C.4J~' H1&gt;~t1•
and Btomt'dJ,al 5dmrw C.t.•, l mvcrsll)
c£ Ill~ \ rk Bull• &lt;' l , \CI&gt;II) Pt:"
Ull&lt;'m I lt'lr,&gt;fhll"' [_•, 1lo."'~

~

11, bnngmg wuh 11 u l'C\\ \1edtc.tl \lumm &amp;ard of
rm cnthus• ,u._ .tbout !&gt;C'rvmg .h) our new pre&lt; 1dcn• La'&gt;t &gt;car's Board under
Hamson set the htghtst .,!a"ldards for us to emulate. In lQ92 1991 we will
such pre\ wusl} "-UCl"l''i~£ul .1c uvmco; ,,., the ph~ stCtan c.trcer presentations to
sophomon mcdKal sllld('nts, .md the onent.tuon scssrono; for freshman
restdem doctor; \\ l pbn .mother )Jnuarv rcccpuon for c.cmor &lt;;tudcnt&lt;,, along
Jar out of-tO\\ n rrccptiott- for alumm m oth::r c tlle&lt;.. &lt;.)ur C,pnng Chmcal Day
promtses.t forum cl ...ontcmpon.tl)" medtc.tl cone em, mtxc:d \lo ith the pleasures
old fnends Our I1tsrm1:m&lt;.hed \1edKal Alumnu&lt;&gt; Award will he presented in
'-",,,.,mh..dl:•n Yale Emcntu~ Profc-,.&gt;&lt;&gt;r Dr \!£red L,,m.
&lt;.urrc'lth \\c .1rc \\orkmg on some nt-v. tde.lS for the commg )car
mdudmg.tn IPR&lt;.) rmx k tnal '&gt;t.lntnar and a M.tt&lt; h Da\ &lt;elcbration for
scmor., \\ ( '' tll conunuc our ltat"&gt;&lt;m \\ 1th the Mcchwl AdmissiOns
( ommlllrc to fL•IIO\\ our lf'J.'fiC.\ stud... nts In addiuon, \lof' f'xpcct to
recogmze unsung hlll dl'&gt;Cr"\'ll'J;alumm \lolth a ne\\ catcgorv of Alumm
t\thtevement r\\\ards to be presented at a &lt;:.pcctal spnng luncheon. We
are seeking opponumucs to suppon and acknowledge our hardworkmg volunteer fawh~ \\care also cono;rdcnng a Medical Alumni
Who's Who to help '&gt;pread the \\ ord about our more promment
da~mates fhc \car ahe.td prom o;cc; all the cxcuement and mnovauon
together our far-flung medtcal school fam1ly.

1k

'"""'·"
&lt;;end address change• w n.r llu[jalfiPh}
siCtull and Bwmrdual ~nrnllsr. 14f\ ( f'&gt;
Addu'"" H\5 !l.tJm 'ltrru. Buffalo New
Ycrk 14214

Don Copley, M.D., '70

D(JY\ oJ..d. P. ee,

rtto,

MD .

�VOL26,No.3

5UMMER1992

II Research
II Hospital News
IJI Country Doctors
C. K. Huang, diredor of the Healtll Sciences

Library, re&lt;eived the first John and Margaret
Naughton Spe&lt;ial Recognition Award at the
meiKal school' s annual fCKulty meetilg. Page 22

Rural physicians see more patients, work longer hours and earn less money than
their urban counterparts. So, why do they do it?
Diane Zwirecki finds out.
Dr. Muse In an age of scientific specialization,
some physicians find inspiration and expression
in the humanities. Mark Hammer examines the
phenomenon.

_..,m

--.111

m

ASpoonful of Humor

Stu Silverstein, M.D., learns
about political correctness.

m

MeaKal School

* Buffalo Gueral
Hospital sends
badly needed
meiKal suppttes to
Third World
nations. Poge 4.

Aguide to
pahtically
corred
medspeak.
Page 18.

The School of MeiKine and
Biomedical S&lt;iences graduates Its
146th dass. Page 25.

�[1]

. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . ..

..

Exercise no substitute
for not smoking
n a collaboranve effort to determine
the connecuon between hfestyle habits and blood levels of htgh-density
lipoprotein cholesterol, researchers at
UB and the University of Naples have
found that smokmg and intensive exercise affect HDL in the body, but with
opposite results.
Based on an analysis of the habits of797
men who participated m the Olivetu Heart
Study in aples, Italy, they found that
nonsmokers who paructpated in vtgorous
sport acti\ity- at least four hours a week
for nine months a year- expenenced an
average lO percent increase m levels of
HDL, the c;o-called Mgood cholesterol.M
Smokers, however, showed no statisticall&gt; relevant mcrease m HDL levels, no
matter how hard the&gt; exerciSed.
Results of the study were
recently published in Preventive Medicme.
"From a prevention potnt of
view, this clearly says that you
cannot run and sttll do everything else you want, because
physical activity will not be
able to overcome other bad
habits," satd Maurizio
Tre\isan, M.D , intenm chair
of the Umversit) at Buffalo
Department ofSocial and Preventive Medicme and one of
the pnnctpal authors of the
StUd).
It has been known for some
time that smoking is an tmportant nsk factor for developtng
heart diSeaSe and that smokers
have lower levels of HDL tn
their blood than non-smoker...
Meanwhile, studies have
shown that high-density lipoproteins help protect against
heart disease and that vigorous

f)

BU~,ALO

PHVStCIAN

exercise mcreases HDL levels.
~It appears that smokmg and physical
activity act on high-denSH) ltpoproteins
by the same mechanism, but have opposite effects," Trevisan said. "Mostltkely,
they affect a number of enzymes, primarily lipoprotein lipase, a key enzyme in
HDL metabolism. Smoking may decrease its activity, while exercise may
increase it."
The Findings were part of a larger study
of the effect of lifestyle habits on HDL
levels.
The UB-UniversityofNaplesstud) supported previous findmgs that smokmg
and being overwetght decrease HDL levels. Moderate alcohol consumpuon and
\igorottS, sustained exercise increase H D L
while low and moderate levels of phystcal
+
activity have no effect.
BY

LOIS

BAKER

Internationa I rehabilitation
assessment standard

developed at UB
he first international standard for
measuring the effectiveness of
medical rehabilitation, developed
by a University at Buffalo research
group, could launch international
research in the field and lead to
refonns in the way Medicare reimburses
the multi-million dollar rehabilitation industry for its services.
The Uniform Data System for Medical
Rehabilitation was developed through a
three-year, $330.000 grant from the , ationallnsutute for Disability and Rehabilitation Research.
The keystone of the system, e11:plained
Carl V. Granger, M.D., professor in the UB
Department of Rehabilitation Medicine
and one of its principal developers, is the functional independence measure, or FIM, an
easy-to-use instrument that allows trained personnel to assign a numerical value to a
patienl's ability to function
based on the performance of 18
physical and mental tasks that
are part of a typtcal daily routine. By assessing pattents
throughout treatmem and after
diSCharge, their progress, outcomes and cost of treatment
can be measured.
The method has been embraced enthusiastically:
-.r More than 150,000 patients m 337 facilities in 47
states have been assessed since
its introduction in 1987.
._;. FIM has been translated
~ into five languages.
~.;.. Twenty-five facilities in
~ Aust~alia and five in Canada arc
~ sendmg data to UB's Center for

i

ANI)

BtO..-£DICAL,

SCt&amp;HTIST

I

lit

lit

2

..

�·························································································· m

r3

m

Functional Assessment Research, with
japan expected to come on-line next.
.;. Seventy-five VA rehabilitation centers will jom the system shortly
Data collected from participating facilities are fed into a spectally destgned database that generates reports for each facility
to compare its performance with similar
facilities regionally and nationally.
In addition, UB has opened a new database to serve skilled nursing facilities, and
another is being developed to process
information from m-home therapy services. Researchers have also adapted and
are currently tesung the assessment
method for pediatnc application, calling it
WeeFlM.
+
BY

LOIS

BAKER

Muscle rehabilitation with
non-aerobk exercise can
improve aerobic fitness

..

VB study that used persons with
osteoarthritis of the knee as subjects has shown that strengthening weak knee muscles with nonaerobic exercise also improves
cardtovascular fitness.
adtne M. FISher, Ed. D.,and colleagues
in the departments of rehabtlitative medicine and physiolog} tested the subjects'
aerobic fitness before and after three
months of ISOmetric and endurance knee
f!exton and extenston exercises known as
quantitauve progre$tve e.xerctSe rehabilitation.
After the program, the participants
gained 65 percent more aerobtc power
and could walk faster and exercise longer
than previously. The study showed that,
for this populauon at least, muscle rehabilitation alone can improve aerobic fitness. The findings were reported recently
+
in Gerontologist.
BY

LOIS

BAKER

nme percent having it in at least one meal
per week
._;. Those with a higher frequency of
eatmg the fish tend to eat larger serving
sizes at one meal.
._;. Blacks and Native Americans, along
with anglers with fewer years of education
and lower LOtal household income, reported the most frequent consumption of
~ fish from Lake Ontario.
~
~There is still a large percentage of people
S using thiS resource, despite the warnings,··
~ said john E. Vena, Ph.D., principal invesugator and associate professor of social
and prevenuve medicine at the Universll)
at Buffalo.
•
•
Funded by a grant from the Great Lakes
Protection Fund, the study was based on
questionnaires returned by 11.717 anglers
bile more than 90 percent of who purchased fishing licenses in 16 upanglers in upstate ew York state counties from October 1990 to Febare aware of the state's health ruary 1991.
For six counties that border Lake
advisory warning that fish
Ontario,
more than 10 percent of the anin Lake Ontario are chemiglers
reported
consumption of fish from
cally contaminated, most
have not changed their fishing habits or Lake Ontario at least once a
fish consumption, according to prelimi- week.
Venahasbeenfunded
nary results from the largest study ever
conducted on the health impact of eating by the Great Lakes
ftSh from the Great
Lakes.
The study of more
than 11,000 anglers
by UB researchers
showed that less than
half have changed
their fiShing habits
and only
20 percent have cut their consumption of
Protection Fund
fish from Lake Ontario, the most chemifor
follow-up
studies. incally contaminated of the Great Lakes.
cluding
those
of
birth outThe study also found that:
comes
m
female
anglers
and wives of an._;. Sixty percent reported consummg
about the same amount of ftSh from Lake glers, and a study that '.viii focus on 350
Ontario in the last year as m prevtous anglers in the responding group that will
years, while 30 percent reported eating mvolve taking blood and hair samples to
determine who much of the chemicals are
less.
+
.._;. One-third reported consuming the being absorbed by their bodies.

Eight out of 10 anglers
1gnore wam1ngs
about Great Lakes fish

fish in at least one meal per month, with

B

Y

L

OIS

BAKER

�s

······ · ···· · ··· · ······························ · ··············· · ···························

Buffalo General Hospital
shi ppi~ bad~ needed
medkal supplies overseas
uffalo General Hospital has
launched a project to ship badly
needed medical supplies and
equipment to hospitals in Guatemala and the Philippines.
Known as the Overseas Medical
Assistance PrOJCCt (OMAP), the program
was orgamzed b) BGH surgeon F fero
Sadeghian , M D , and NanC} E.
\ltazuchowski, assiStant admmiStrator for
professional affairs.
~While traveling in different pariS of the
world, I found that so many countries are
in dire need of the type of medtcal and
surgical items that we discard," Sadeghian
The St. Louise West Side Health Core Center, site of Sisters Hospital's new OB/ GYH cfini&lt;.
satd. As an example, the BGH surgeon
explamed that once a package ofsutures is goal is to conunue sending these types of counsel.
Mazuchowski said support for OMAP
opened and parually used, New York State ttems, but also to provtde hosp1tals with
larger
equipment
whtch
is
no
longer
in
usc
has
come from several sources, including
health department codes do not permit it
here," she explained.
the hospital's medical and dental staff
to be resealed and used
In addition to the two organiz- which donated money to cover shipping
elsewhere. He noted
ers, other BGH staff mvolved charges for medical and surgical
that a disclatmer ac+
in OMAP include Lynne supplies.
companies each package advising
Blanchard, R.N.,
sterilization of the supplies,
if appropriate.
Linda Butterfass,
R.N., Mal) Ann
The OMAP commmee
meetsquarterl) to evaluDannenhoffer,
ate the proJect, explore
Phann. D , Charles
,
\
ways to expand the
Lakso. \thchael
program and to
\
'
F "oe. ~1 . 0..
prepare pack~
~'~~.:;;.~.......
'vttchael
H.
ISters Hospital has opened an obages for shtp- ............_ •
stetncs/gynecology clmic featurl ping. To date,
mg a wtde range of women's health
t threeshtpments ·
senices and a bilingual nursmg
~
have been sent - staff at 209 Niagara Srreet, Buffalo.
to Roosevelt
The clinic is located at the St. Louise
Hospital, a
Also on the West Side Health Care Center, one of the
2,000-bed facthty
commtttee are Rtchard hospttal's satellite facilities.
Moore and Susan Regan,
in Guatemala, and
"We serve women of all age categories
several to St. Martin de
who
are
providing
pro
bono
with
various needs, including teenagers,
I
Porres Charity Hospital in
legal services in connection with menopausal women and geriatric pathe project. They represent Magavern tients," notes joyce D. Heath, M.S., comManila.
"As we proceed with this project, our and Magavern, the hospital's general munity services coordinator.

Sisters Hospital opens
obIgyn servke on
Buffalo's west side

l

.

0

8U,.P'AL0

PHYSICIAN

AND

BIOMI[O

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SC.I:HTIST

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..

�. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . [1]
The clmic 1s also a site for the SISters
Hospital Prenatal Care AssiStance Program.
The center's staff includes an obstetrician/gynecologist, a registered nurse. a
nurse practitioner, a social worker, a nutritionist and a financial advocate.
The clinic also serves chemtcally dependent and high-risk pregnant women. +

ment of radiation medtcme at Roswell, "It
takes less than lO minutes, seems to be
more effective, offers greater patient safety
and convenience and significantly reduces
length of hospitalization. And the potential uses of this treatment seem to be
limited only by our imaginations."
Shin and his colleagues arc currently
administering brachytherapy to patients
with recurrent, inoperable lung cancer,
particularly those who have failed to respond to conventional radiation therapy.
Patients with tumor obstructions in the
esophagus may also benefit from this treatment, Shin said, as well as pauents with
prostate, breast, head and neck, cervical
and endometrial cancers.
+

Sisters Hospital plans to
open ambulatory care
center in Amherst
Roswell Park Cancer
Institute first to offer
high-dose brachytherapy
igh-dose brachytherapy-a new.
more efficient method of delivering radiation d1rectly to tumors
- is now being offered to area
cancer patients at Roswell Park
Cancer Institute
Brachytherap). m which a radioacuve
pellet is attached to a thin, fieXlble catheter
and placed directly on or near the tumor.
has man) advantages over convenuonal
radtauon therapy The procedure allows
the dehvery of a very htgh dose of radiation that rema1ns essenually confined to
the LUmor area, sparing the surrounding
healthy tissue. In convenuonal radiation
therapy. radiation IS delivered indirectly
from outside the paucnt's body.
According to Kyu Shin, M.D., chair of
radiation oncology and head of the depart-

he Amherst Planning Board
has approved a Sisters Hospital plan to open a fullservice ambulatory
care center on
Harlem Road at
Sheridan Drn•e in
Amherst.
The Sisters Amherst ""
Health Center will occupy approximately
15,000squarefeetof
a four-story, 40.000square-foot medical '
office
building
planned by Ftrst
Amherst Development
Group.
The center will provide
mammography, X-ray and CT scanning,
laboratory and blood draw station and a
full range of outpatient primary•care services.
The hospital's Corporate Health Ser-

vices division will also be a part of the
Amherst complex. as well as a medical
reference materials room and conference/
classroom areas for medical meetings and
seminars.
Ststers Hospital medical staff will also
maintain offices for specialties including
08/GYN, cardiology, orthopedics, internal medicine and family practice at the
center.
"The building of the Sisters hospital
ambulatory care center results from the
hospttal's need to bring many of its outpauent senices closer to the consumer. Our
location will pro,ide easy and quick access from all the northern suburbs,~ said
Sr Angela Bontempo. president of Sisters
Hospttal.
The remainder of the space in the medical office butlding , ...;JJ be leased to physiCians and other health care specialists
whose practices are compatible \\.ith
the Sisters Hospital facility. The
medical office building will be
located direclly at the
Harlem-Sheridan Drive
exit of the Youngmann Memorial
Highway. It
is scheduled
to open this

fall.

Artist's rendering of
Sisters Hospital's planned
ambulatory care center.

+

���•

"Most of these people are my patients, if
not friends, then acq11aintances. I just enjoy the
rural setting, the people and the attitude. "
Rural phvsrcrans sec more patients,
work longer hours and cam less money
than their counterpart~ m maJOr cities.
The\ are more sevcrd) affected b\ shonagesof con~ultants, nu~es, thcraprsts and
social support agcnw:., So, why do they
do it? And why do other doctors opt for
an urban practice?
For many, the choiCe b based on their
upbnngmg. For others, lb srmply a lifeume dream come true.
Ask farmh pracuuoncr Wallace alter
wh) he chose a rural practice and he's at
a loss to answer- verbally. Instead, he'll
rm,te you to hop m hrsjeep and maneuver through the 35 acres oft and he and his
,,;fe Debra O\\ n m the lulls of Boston,
1\Je,-. York. From therr mountainside
home which ha~ the look and atmosphere
of a ski chalet they overlook a breathtak-

0

8U,P'AL0

PHYSICIAN

ing scene of foliage and wildlife. from
lheir living room, you can sec the renovated 170-year-old farmhouse a quarter of
a mile mva) which houses their JOint practice.
Debora and\\ allacc. one of the the first
husband-and-\\ife teams to complete residenc&gt; trainmg at the State UmvcNl\ of
'\ew York at Buffalo. clear!)' arc dchghtcd
"ith thetr choice ofa practtcc locauon. In
Wallace's opinion, they ha,·c the best of
both worlds, ,,;th ready accc..,., to care m
Buffalo. where ~children·s Hospnal 1s a
17-min.ute \-1edE,·ac awa} \\ c're luck)
here."
In Boston, '\e"' '\ ork, and the ncrghboring hamlet ofPatchin, C\'CT} bod) knO\vs
evef}rbody else and adults and children
alike are on first-name bases. An hourlong visit for breakfast at a local restaurant

AND

BIOMEDICAL

brings in at least a half-dozen guests who
stop and chat ''ith the doctors. Referring
to the restaurant's clientele, Wallace Salter
notes that "most of these people are In)
pauents. if not friends, then acquaintances. I just enjO) the rural seuing. the
people and the attitude...
If the Boston hills are off the beaten
path, then the Salters' ex'J)Crience as resrdents m Point Barro". Alaska, was downright Siberian. Point Barrow is a town of
4,000 located 330 miles north of the Arctic
(rrclc Its people are mega-miles from the
nearest Cit). m geographic location as well
as in mind-set. '-:otes Debra Salter, "The)
still have their medicine women ... The)
still do things like cupping (placing heat
cups on the back) and burning to remove
bad sprrits." Both Debra and Wallace
spent time in Alaska caring for the resi-

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�dents of Point SarrO\\ and se,·en outlying
\'Hlages \\ithin a 300-mtle rad1us Wallace
made two mps from Buffalo to Pomt BarrO\\, Debra. one, accompamed on her
venture b\ the1ro:.onjcremy, who was two
year.; old at the ume. The family lived at
the 14-bed hospital where the doctors
worked and Jeremy burned off toddler
steam by running in the corridor.; (At 70
degrees belO\\ zero. planng outdoor.; was
out of the quesuon ) Many of the Salters·
pauents were Alaskan p1peline workers
and their famJI1es. Complex cases had to
be transferred to Anchorage. 700 miles
and two-and-a-half hours away by jet.
Wallace Salter recalls treating a head injury on a pipeline worker: he was a1rlifted
to the scene of the injury and mformed by
his pilot that he had 11 minutes to disembark. suture h1s pauent and return to the
plane before fuel ran out (at 70 degrees
below zero. the temperature IS too cold to
restart the plane) I accomplished ll m 13
minutes and ....-e made it back safclv,'' he
recalls.
Home for mam a Point Barrow family
was a tarpaper shack. and basic necessities
such as indoor plumbing often simplv
were not available "\\ e·d treat a chtld
\Vith an ear mfecuon and recommend a
humidifier and the qucsuon wasn't, 'Do
you have a humidifier?' The question was,
'Do you have runmng water or electricity?"' says Debra Salter. 'They melt icebergs for fresh water," adds Wallace. Tuberculosis, syphilis, hepatitis and other
infections ran rampant man area where a
sanitation truck visited homes datlv to
empty out waste.
In sharp con~t to the1r Alaskan e.'.-penence and ultimate choice of a rural practice,
the Salters both have experience m urban
mechcine, ha-.ing worked in \'arious Buffalo
hospital emergenC\ departments. For eight
years. they res1ded in the inner cil) and are
convmced that their urban medicine counterparts could •keep ~anhattan,just give me
that coumn'Slde"
"It wasn't neccssanh the pauents as
much as ll .... as the hfcstvle," explams
Debra. "I JUSt never had the mner-cily
attitude. Part of the d1fference for me was
my upbringmg. I was ra1sed on a 6,000acre cattle ranch m ew Mex1co. I was just
much more used to rural-type living in the
first place."

�Recent studies show that two trends
related to phys1c1ans choices of a practice
location arc similarity to their 0\\11 home
town and spousal preference. In the Salters' case. both these theories appl). and
their decision to open a practice in a
country scuing ,.,.as mutual To sa\ thev
are happ)''"ith their choice of both profession and lifestyle c, an understatement
Ther speak enthus1asucally about every
aspect of it, even cham sa\\ season "We

have things that walk mto our office that
I would nner get 1fl '"as practicing in the
city... says \\ allace. "Last fall ''as chain
saw season. 'HO\\ do) ou get those annoying blood stains out of vour chain saw?'~
Catherine Weeden. \t D also !)C~ her
share of chain saw injuries. &lt;l'&gt; well as
farmingaccidentsandsimilar mediCal miShaps. Weeden completed her famll~ practice training at UB in june 1992 and became medical director of the Unt\'Cr'&gt;ity's

Rural Health Campus in Cuba, 70 miles
south of Buffalo. The campus was funded
b\ a 1988legislative grant from 'iew York
State. sponsored by the state's Corrurus'&gt;IOn on Rural Resources. Physicians began seemg patients at the campus, located
on the grounds of 26-bed Cuba Memorial
Hospital. mjuly 1991. In less than a vear.
'&gt;taffed by a medical director and t\\."0
re'&gt;idents. the campus has handled 4,000
patient ,;sits Thomas Rosenthal. M.D..
director of the rural campus, comments
that "we're where we'd normally be after a
couple of years an urban site."
''I'm not sure why I chose a rural practice,'' says Weeden. "I've just always
dreamed of being a small-town country
doctor."
In contrast to Debra Salter. Weeden's
upbringing does not mirror her choice of a
rural area in which to live and work. She
grew up in suburban Orlando. Florida,
and attended the University of Tampa
College of 'vtedicine. Her link to :-.le"
'r ork's heartland is her husband. M1chael.
a minister in Olean- at 15 miles away the
nearest Cit\ to Cuba. She describes her
patients as ~farmers and small busmessmen. Animal bites, rabies vaccinauons
and farm-related accidents are common,"
she notes, as are injuries to boaters on
nearby Cuba Lake. Recently, Weeden treated
"horrible lacerations" on
a gentleman whose face
was caught in a barbedwire fence. "It's not really
very glamorous," she
says. "He was wrestling
with his dog."
like her peers from UB,
Weeden spent the ftrSt
m·oyearsofherres1dency
training at the Deaconess
Family Medicme Center,
an inner-city subsidiary
of The Buffalo General
Hospital. She sees hkenesses, as well as stark
differences, bet\veen her
urban and rural pauent
experiences.
..Actually, they're very
similar populations in
some ways," she notes.
"Both are largely Medic-

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�aid patient~. The difference 1s that here,
moreofthcmarC\\OrkmgMcdicatdpcople.
The) work hard. but don't cam enough to
get med1calmsurance.
Referring to her adopted rural hfestyle,
Weeden says, "It's been a pleasant surprise
working here. More and more, I can't go
anywhere without ~omeone knO\\ing my
name."
Access to mcd1cal tcchnoloro , circa
1992. is nota problem. "In th1sage,you're
not a.., isolated as you u..,cd to be," she
commenLs. One of her colleague:, m Cuba.
Kimberle\ \tarkowsk1. \-1 D , echoes
\\'ecdcn ~ op1mon Dbtance hasn t Jeopardized an) cases, note'&gt; \-tarkowski. "In
an emergenC). v. hen atrtransport becomes
necessary, any tunc seems to long. But in
all reality. it's reasonable."
Born in the tin\ communit) of~ewfane.
t\ew York, and raised 111 the nearby to\m
oflockport, Markowski d1dn't thmk t\\ice
about JOinmg her husband Geoffrev in
family pracuce and movtng to a spre;d of
land that measured "257 acres, at last
count." When they're not treating animal
bites or gunshot wounds, the Markowskis
raise three daughte~. 14 head of cattle,
fi"e rabbits and a dog.
Their work represents "famih practice
in itsenuret)," &lt;&gt;avs Kimberlev Markowski.
"The best place for famth pracucc IS m a
rural setting, where there s more of a need
than there is in the cit\ In the Cll), there
are specialists for e'wythmg. Specialists
tend to cluster in the cll~ where thev can
be reimbursed for thc1r ~pecialue:, ..
Rural or urban. canng for people. building relationships and '&gt;culpting a hfest\·le
rooted m personal cxpcnence is what choosmga practice locauon ult1m.11ely
comes down to. And for
some of toda) \recent medical school graduates, mral
medicine is the right choice.

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t's a long, long way from
modem medicine to Point
Barrow.
Traveling to this Alaskan outpost 330 miles
above the Arctic Circle,
Drs. Debra and Wallace
Salter may as well have
entered a time warp. Traditional native medicine in
Point Barrow borders on
the prehistoric; for many an Eskimo,
the first line of care is a medicine
woman who uses techniques such as
burning the skin's surface with coins or
metal cups to ward off evil spirits that
are believed to bring disease.
"The people there equated their
medicine woman with a witch doctor.
She was very highly regarded ," says
Debra Salter. The Salters spent several weeks during their residency training living in and working from a 14-bed
Point Barrow hospital. " If the traditional means of treatment provided by
the medicine woman didn't work, then
they'd seek us out for care."
In a procedure commonly known as
cupping, Eskimo medicine women heat

BIOMEDICAL

metal objects and place them on the
back. "Evil spirits are associated with
illness. If they can get the evil spirit to
leave the body, they believe the illness
will go with it," Debra Salter explains.
The Salters saw four or five cases a
month, many of whom were children,
brought to the hospital only after such
traditional native techniques had failed
to cure fevers, ear infections and similar childhood maladies. But not all the
natives' medical problems were minor.
"Some of the disease processes in
children and in the population in general were similar to those you'd find in
a third-world country ... advanced tuberculosis, hepatitis B... it was amazing," says Debra Salter.
Amazing, perhaps. to the physician
educated in a major American university. Buttothe Eskimo bred in Alaska's
most remote geographic comer, it was
a simple matter of respecting timehonored traditions passed down through
the generations.
One man's witchcraft is another
man's cure. Perhaps it's just a matter
of what you believe in.

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In

an age of specialization, n1any p/,ysicians find

inspiration /ronz tlze arts.

By Mark Hammer
ver the last 50 years or
so, American cuilure
has come to celebrate
s pectahzauon, not
only in medtcme, law
and academic pursuits,
but in virtuallr every arena of human
acuvity from mortgage banking to cosmetologr, ,..·here an electroly:.ist can seldom
give r ou a good pedicure.
In the field of medicine, specializauon
is eptdemtc Where once the GP tripped
up and d own the statrways of our hves,
humming a tunc of his own creation,
painting a hulc on thcstde, writing poetry,
perhaps doing an autopsy now and then,
there now gallops a he rd of
otolaryngologists, orthopedists (and orthopedic surgeons), neurologists (and

neurosurgeons) , urinary incontinologists,
endometrial samplers, comeaologists and
investigators into the structural relationships of dihydorpyridine-l)'Pe calciUm
channel antagonists.
Perhaps because we cast individualism
in a sacred light, Americans denve great
comfort from the label ~expert." After all,
who do you want to sew up your aorta?
One way for practitioners to augment
the narrow focus of thetr scienufic pursuit
is to explore a different creative realm
entirely, giving free reign to the intuitive
process in a relief from the sctentific. We
know the dogmas and strictures that define the realm of the mcdtcal expert can
accommodate the errant muse, and have
often enough. The world of medicine has
yielded great poets, authors and compos-

ers. And sometimes, the arts have yielded
a physician or two.
Anton Chekov (1860-1904), the Russian playwnght who wrote such dramatic
masterpieces as The Seagull and The Cherry
Orchard, was a (sporadically) practicing
physician who lived a life devoted to the
arts. He wrote his first short stories as a
medical student at Moscow University to
help pay off family debts. Although his
reputation as an artist far exceeds his work
m medicme, Chekov's writing continually encounters and questions the human
spirit and the motivations which produce
the emotional and physical environments
within which the Russian people lived at
the tum of the century. His characters
continually face a moral struggle in finding their true selves, only to find that the

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�tragic aspects of life are often comed1c as
well.
Another example of a man of medicine
who devoted his life to the arts ts the
American poet W1lham Carlos Williams
(1883-1963) 'low v1ewed as a major
contributor to American moderniSt artistic ach1evement, \o\lilliarrJS was a general
practitioner m Paterson, '\ie,... jerse}. for
most ofh1s adult hfe He spumed the large
city of New York, both arusucally and
medically, in favor of a small commumty
where he did everything from setting broken arms and treating chronic headaches

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to perfonrung emergency appendectonues
and making house calls to deliver babies
And yet Williams produced a bo&lt;h of
work that includes over 1,000 pages of
poetry, se,·eral plays, collections of short
stories and books of essar:. and an autobiography. An annual poet!) contest, open
to medical students around the country, is
sponsored by the Human values m Medtcine program at Northeastern Oh10
University's College ofMedtcmc in honor
of Williams.
Williams was presented with an honorary Doctor of laws degree by UB during

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its centennial celebration in October 1946
(sees1debaron Williams). His sponsor for
that degree, then-Dtrector of Universit)
Libranes Charles D. Abbou. sa1d at the
ume that Williams had encountered and
celebrated ordinal)· American life both
wtth his wnung and his medical practice.
~He has been able to see, understand
and to express the larger unities of American hfe," Abbou said. '·Like the Universit}. whose hundredth year we celebrate,
he too began in medicine, kept faith with
all that it demands and sought beyond to
that large store of knowledge that fits

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�man's mind to grasp the ends of thought."
Williams was also a celebrated participant 10 the Niagara Fronuer Convocation
in Buffalo m 1951, whtch explored the
possibilities of Amenca m the Iauer half of
the 20th century A large collection of lus
papers is owned by the Universny as well.
Williams and Cheko", and numerous
others like the Enghsh poet, dramaust and
physictan Thomas Campion (1567-1620)
and the Austnan doctor and composer

understand a great deal of disparate information.
-1 believe that doctors think in a way
that is amagonistic to poetry," he says.
~because phystctans are often mflextble m
their thinking. 'My Simple premLSe IS
doctors aren't trained broad!}· m the liberal arts. Their educauon IS generali}' very
specialized. Poetic thought goes 360 degrees. And the process of poeuc th10kmg
brirlgs the poet mto other mtellectual ar-

the physician, or the poet, to encounter
new prirlciples that become universal, according to Charles Bernsteirl, a prominent
American poet who holds the David Gray
chatr ofPoetry· and Lettersat UB. Bernstern
has wnuen and edited over 20 books of
poell) and essays on language. As a ghost
wn ter for 15 years, Bernstein wrote monographs for physicians for medical education publications and abstracts about new
experimental drugs and procedures for

'~ grounding in science alone won 't make anyone a doctor.
There also needs to be an understanding of the intuition that
tells us what the whole individual is."
Peter Lichtenthal (1867-1924), spent a
great deal of their hves pursuing artistic
beauty while adhering to their calling in
medicine. One reason for tlus lies m the
process of commumcauon that underlies
much of what an arust does, accordmg to
Wilham Coles, M.D., chatrman of the
depanment of ophthalmology at lJB's
School of Medtcine and Btomedical Sciences. Coles is an accomplished poet published wide!&gt; 10 Buffalo and in magazines around the country - who holds
Wilharns as a maJor mfluence on lus 0\\-'11
writing. He 1S also a Jazz mustctan who
bills himself as "Doctor jazz," specializing
in heritage jazz and blues on the banjo and
vocals.
"I started writing creatively after Igraduated from medical school. I went imo
poetry because 1 was very interested m
idea transfer as an educator as well as a
public speaker," explained Coles, who has
also taught Life Workshops m poetry at
UB and won the Callenwold Poetry prize
in Atlanta. "Poetry 1S appeal10g because tt
is made up of very• concentrated and well
thought out tdeas. It's what 1 call the
process of poetry, and u centers on communicauon. My medical school trammg
left out that kind of process-onented thinking. Let's admu It, most doctors are not
very communicauve."
The poeuc process brirlgs the poet into
various areas of thought, according to
Coles, who has also taught poetry·at Emory
University in Atlanta, Georgta. And it is
through that kind of intellectual diversity
that the poet is invested with the ability to

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eas continually. Poetry is the new sensitivity forme, the seventh sense, if you will,
that also allows me to reach people across
a universal spectrum."
An intense attention to detail is what
makes creative photography and surgery·
complementary, according to NanC}
Stubbe. M.D., a clinical physician at UB's
University Health Services and a facult}
member at the medical school "Wllh
photography, you need to spend a great
amount of attenuon to set up a good stillhfe scene, for example. If the least thing is
wrong, the picture is ruined," she explained.
"In that respect, it's very simtlar to
medicine, where a physician must be very
conscious of detail in her work. And with
both, you must devote yourself entirely to
the task at hand."
Another parallel between med1cine and
photography is in the intricate observation essential for both, said Stubbe, who
regularly enters her photographs of nature in local photo competitions and has
had some of her work published in a local
medical newsletter, Medical News. "As a
physician, you're taught how to observe a
patient very· carefully. whether before,
during or after treatment. The same goes
for photography. But being a photographer made me learn how to observe without someone speaking about symptoms.
In that way, photography has made me a
better clinical observer."
Changing focus, using the mformation
from one field to shed light or bring new
intellectual possibility to another, allows

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pharmaceutical companies. He also edIted the Canadian edition of Modern
Medicme and wrote and edited over 20
books of poetry and essays on language.
•J loved the precision of the medical
nomenclature in that it was very specific.
But thewritingl was asked to do was often
relatively dry·. and most of it was recycled
mformauon. And that writing.~ he explamed, "earned a sense of neutral descnpuon, which is the exact oppostte of
m} poetry~
Bernstein said he began to notice that
his medical writing began toaffectlusown
wnting and thinking. He maintair!S that
medical writing both altered and expanded
his perception of language. ~I found that
the medical terminology, the phrasing,
staned to creep into my creative work. For
example, I wrote a piece about
'dysraphism,' which means the congenital
mis-seanung of body parts. And that
description seems to have caught on regarding what my creative work does, in
general. It's like bad stitching. I'm generalh fascmated by any descnption of abnormality"
It IS the large spectrum of feeling that
gives doctors-as-writers their field of exploration, accordmg to Richard Seltzer,
M.D ,a retired professorofsurgeryatYale
Umverstty's School of Medicine and author of six books of shon fiction and
essays. His most recent work, Down From
Troy, a memoir about lus boyhood in
Troy, NewYork,duringtheDepression, is
forthcoming this summer from William
Morrow Publishers. "I've worked very

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�hard to transfer the feeling of surgery mto
my writtng. And there is a strong similarity between the two for me Both are
techniques, crafts." he c;rud won a very
simple level, you have a scalpel that draws
bloodandapenthatdraw.. mk ln\vnung.
you're suturing words together and \\'lth
surge[}. you resutunng together the body.
I want to report, m the most compelling
language that! can use,the suuauon of the
human bod)."
11

Tommy Dorsey, Benny Goodman, Glenn
Miller, and we do a few modem tunes as
well." he said. WThe number one reason
why we do thiS is for the fun of it. It gtves
us a chance to do somethmg outside of
medicine that we all enjoy"
\Vhile Schiller finds music to be an
escape from the daily rigors and pressures
of being a ph)'sictan, a way to enJO}' the
com pan) of his colleagues. the technical
aspects ofbeing a musician resonate much

Washmgton for a year. ~A grounding in
sctence alone won't make anyone a doctor There also needs to be an understandmg of the mtUttion that tells us what the
whole individual is.··
She also points to the technical expertise associated with both fields as bemg a
point of convergence, although she admtts that the basic discipline she gained
from studying music for most of her life
has made her a better physician. MThere 1S

0n a t'ery simple let•el, you lzat'e a scalpel that draws blood

and a pen that draws ink. In writing, you're suturing words
together and with surgery, you're suturing togetlter the body."
Seltzer, who didn't begm wnting until
the age of 40 (he's now 64), satd that once
he became entranced with language, his
abthty to sense and empathtze with his
patients mcreased dramaucally. "In making myself mto a writer, I became a better
doctor I saw that! \\.'as much more in tune
with my pauents as human bemgs," he
explamed. "Because with things like compassion and pll), some people have it
naturally and others get it b~ enduring
thetr own suffering. I found ll through
wntmg
In his forthcommg memOir, Seltzer
writes of his boyhood and the stress of
having parents who had very dtfferent
career choices in mind for their son; his
father was a doctor and his mother was a
singer. "My father wanted me to be a
physician and my mother wanted me to be
an artist. I guess at 64. I've finally satisfied
both of them," he laughed.
And satisfacuon, whether personal or
otherwise, 1S often mouvauon enough lO
want to create provocau"e prose or a
prisune photograph, or mterpret a !)'tiCal
ballad by Benny Goodman. says Sheldon
Schtller, M.D., an ophthalmologtSt from
LoutSvtlle. Kentuck), and the onginator
of WThe Doctor's Band," a popular 25piece dance band there. He plays the
saxophone "I started ll over 25 years
ago," he satd.
WThtS band allows us to do something
wewouldn'totherwisedo. lt'sareleasefor
our own stress, kmd of group therapy for
us. We're a dance band. We play a lot of
music from the big band era, people Like

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deeper while offering a sense of commuruty not found in the medical profess1on
according to Deborah Shuster, M. D , a
graduate of UB's School of Med1cme and
Biomedical Sciences m Ma) 1992, and a
pathology resident at Stanford liniverstt}
She is an accomplished \iOilSt who has
played in orchestras m New York and Italy
and has a master's degree m mus1c from
the Cruvers1ty of Colorado
"There is definitely too much speclaltzation in medicme. As a pathologist. rm
outside the realm of patient care, but it
doesn't have to be that wa)," she explained.
"There seems to be no conversauon
between the primary care doctors and
myself. 1 don't like that at all." Shuster
said she wants to be a part of a working
community of physicians that is similar to
the community she enjors when plaring
in a symphony.
"Being an artist, marbe I bring a vision
of the whole individual to m) work m
pathology. Because what finall} makes
someone an anist is thatthe) begm to trUSt
an innate sense of intulllon when performing or creating." she sa1d
~And medicine is defmuel&gt; more of an
art than a sc1ence, because there needs to
be a lot of intuition mvolved on the part of
the physician. And a pathologiSt can't
exist without other physicians, and a
musician, at least m my case, can't exist
without the rest of the orchestra. Each IS
one pan of the whole," said Shuster, who
has played in the prestigiousSpolctto Opera
in Italy and the Spokane Symphony in

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a large amount of minute attention needed
to function in both fields. With pathology. I may spend hours looking at one or
two cells in hopes of getting a better sense
of the whole cause of death," she said. "In
mus1c, there is a tremendous amount of
practice, sometimes several hours on one
series of notes, m order to be able to play
a beautiful piece of music."
Bemg able to perceive one's singular
function wilhin a whole structure, mustcall)' or medtcall), is essential to understanding the entire structure, according to
Harold Utt, a French hom player and
currently a student in the M.D./Ph.D. program at UB. "To find the value of what
you're doing means that you must understand how what you're doing fits in with
the whole.
"It's the same in art as in medicine," he
explained. "When looking at a medical
problem, it's very important to identify the
underlying causes. And similarly, in order
to understand the one part you're playing
m a symphony. you must understand the
whole p1ece of music."
He stressed that there needs to be a
dichotomy between the technique and the
art of medtcme. "To be a great anist, you
must do more than play all of the right
notes. You must transcend the ordinary."
said Liu, who studied classical music with
members of the Philadelphia Philharmonic
when he was a teenager. "And it's the same
m medicine. A doctor needs to have
compassion and an intuition regarding his
patients, which leads to a transcendent
understanding of the human animal." +

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and the UB connection
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he lJnivers1ty at Buffalo"s sored Williams for the honorary doctorsupport and recognition ate he received from VB m 1946 at ItS
of William Carlos Williams, Centennial Celebration.
M.D.'s work as a creative artist is
It was also a dose connection to the
made clear by the University's University that enabled Williams to take
massive holdings of Williams' papers. part in The Niagara Frontier ConvocaOver 20,000 documentS in the Williams tion in December 1951, when for two
collection are housed in the University's days, hundreds of scholars and intellecPoetry/Rare Books Collectuals from across America descended
tion, inupon BuiTalo to probe ~The Outlook
cluding letFor Mankind in the Next Half
ters, manuCentury."
scripts,
Williams
working
w a s a
draftS of postrong
ems, notes
critic of
and other mas o m e
terials. The maAmeriterials span
more than 30
years of Williams' career as a
writer-from the \Y';//;am
1920s to the
Carlos \fT;//;ams' poem
1950s.
Williams re- "Lear," u•riften on ltis
ceived his medi- prescription pad- part
cal degree in 1906 o/ UB's collection.
from the University ofPennsylvania. After an internship can artists
in New York and graduate study in the ~Expatn­
pediatrics in Leipzig, he returned to his ates," such as Ezra Pound and Ernest
hometOY.'Il of Paterson, New jersey, in Hemingway - who left their counl910,determined to care for those m his try to go to Europe during the 1920s
own community. Here was a man, as and 1930s. ln his speech at the Convowriter and physictan, who had a strong cation titled ~will the ArtS Thrive or
sense of responsibility to community Degenerate During the Next FiftyYearsr
and country. He would focus his cre- Williams lamented that American wntaU\'e and medical talentS m Paterson for ers had too often harkened back to Euthe durauon of htS hfe.
rope for enlightenment and knowledge,
lt was Williams' close relationship instead of focusing on Amencan mtelwith Charles Abbott, the former direc- lectual and artistic achievementS.
~Our first comers, while their bodies
tor of Umversity Ubraries for the thenUniversity of Buffalo, which brought went forward into the wilderness, turned
much of the material to Buffalo in the back in their minds to Europe,M said
1940s. And it was Abbott who spon- Williams. "After the first burst of

BU,.,AL..O

flHY81CIAH

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BIOMIIOICAL

affirmation at the time of the Revoluuon, and as wealth increased and the
spiritual and Intellectual gradations between individuals became more and
more apparent, the trend of mind back
to Erope and the past grew in appeal."
The second half of the twentieth century could prove to be the period during
wh1ch the American artistic genius
would shed itS dependency on past European associations and become disunct and smgular, said Williams. The
ume, he said, was ~now~ for transformation, for creating a distinctly American
literature.
"Fifty years is a small space of time. It
wdl be hard to say whether we have gone
forward or shpped back during that
ume, but the way tS dearly indicated. I
do not thmk that we shall fail.M
Withams' reputation as a wnter has
grown steadily since
.....
his death
in 1963
when he
was posthumously
awarded
the Pulitzer
Prize in poetry for his

Pictures from
Brueghel, and
Other Poems.
His struggle to propose and define a
literature that would reflect at once both
the s1mple and complex themes played
out m the Amen can experience has been
recognized and applauded by a new
generation of American writers and
scholars. His attitude of looking to the
future to defme people's relationships to
thetr country and itS history continues
to compel and challenge American writers to observe and defme their country's
+
heritage. - Mark Hammer

5CtCNTl8'f

SUMN£11t

1882

G

�A

Spoonful

Po

of

Humor

ically
rrect

Medical Terms
for the
Last

week I was informed by one

of my colleagues that I can no longer use
lhe words "woman~ or "female~ because
lhey contained lhe words "man~ and
"male," which implied a subservient status. From now on she insisted on being
referred to as a "Gyno-American." I said,
"That would be fine, Dr. Zimmerman ...
er, Dr. ZimmerPERSON."
Welcome to lhe "Politically Correct
(PC)" world of the '90s. PC "newspeak" is
no longer just the domain of college campuses and the West Coast. I must learn it,
or risk being seen as a "phallocenoist
impenahst." For example, someone who
is "smelly and dirty" is now considered
"hrgterucally challenged." Someone who
IS lazy is actually "motivationally dispossessed."
If 1t hasn't already happened, we will
need to rethink and rephrase medical jargon so as not to offend patients and politically aware colleagues alike. With this in
mmd, we are proud to present a primer on
"politically correct medspeak." In using
these updated terms, you will be looked
upon as an enlightened man ("testosterone poisoned human") or woman

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..,.. dead :&gt; metabolically challenged

..,.. preemie :&gt; gestationally challenged newborn

After trying to resusCitate ~ir. Da\ 1dson for
over one hour, we declared h1m "metabolicall) challenged" and called off the code.

TillS IS a 27-\"eek

..gescacionall.&gt; challenged
newborn," born to a 27-year-old G2 P2
"Gyno-American."

..,.. drug abuser :&gt; recreational
pharmacologist

..,.. psychotic C&gt; neurotransmitically
challenged

Sub-acute bacterial endocarditis is common
among "recreational phannacologists."

The murderer's lawyer tried to get him offby
claiming he was temporarily "neurotransmitically challenged."

..,.. fungus C&gt; Fungo-American (a
fungus that resides in the United States)

..,.. sociopath C&gt; ethically diverse

Coccidioides is the "Fungo-American" that
causes San joaquin Valley fever.

Charles Manson's swatisha tattoo on his
forehead is a manifestation of his "ethical
diversity"

..,.. hernatopoeisis C&gt; he!shematopoeisis
Her retic. count was up, indicating that

"shematopoeisis" \Vas not impaired

"L\tetabolkall_~

Challenged"

..,.. lice infestation C&gt; pedicular
enhanced
The presence of nits on his halT shafts sug-

gested that he '~as ..pedicularly enhanced "
(~womyn M)

and a role model for future

..,.. male pattern baldness C&gt; reverse
Mohawk

generauons.
On the left are the pohucall} mcorrect
terms. On the right, the latest politically
correct replacement terms. We have also
included a sentence to illustrate proper
usage.

I don't know wh.&gt; men are so self-consoous
A "reYerse Mohawk" malles a man looll so

..,.. amnesia C&gt; memory-tested,
Reagano-centrist recollection

..,.. morbid obesity C&gt; verticulohorizontally enhanced

His "Reagano-centrist recollective" abilities
suggested a worll-up for organic brain syndrome.

1 suggested that he was dangerously

sexy.
..,.. menses C&gt; femses

Fill in your own sentence, please.

"verticulo-horizontally enhanced" and ought
to go on a diet.

..,.. autism C&gt; ce.rebro-centricindividual

Dustin Hoffman's portrayal of a "cerebrocentricindl~idual~wasmagnificent in "Rain
Man ...

W.

hope this guide is helpful. Bring
1t with you to your next QA meeting or
when you give a talk at your next conference. We also welcome additional political corrections.
Author's Note: After this guide went to
press, I was mformed that the term ~poliu­
cally correct" is no longer politically correct Therefore, when you receive this
arucle, please cross out all references to
PC and replace them with "multiculturally
assessed. I apologize to those offended
by my use of the term ~politically correct."

..,.. boring C&gt; REM sleep enhancer
That lecture on the '"or k-upfor slwrt stature

("vertically challenged~) children was sure
an "R£\4 sleep enhancer "

M

..,.. cocaine addict C&gt; cocainist
As a "cocainist," he was at risll for becoming

REF Tilt Ojjat1al Polatuall~ Corrtct DICUon&lt;U) and Hand!AA&gt;.
Htnl") Burd and Chns!oph&lt;r Ccrf

motivationally dispossessed

Vallard Booi&lt;s

..,.. colicky newborn C&gt; infant of choler

Stu Silverstein, M.D., president of Standup
Medicine Seminars of San Francisco, California, lectures nationwide on the role of
humor in medicine.

No matter what we do, this kid will not stop
crying. This "rnfant of choler" is driving me
up the wall.

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" Recreational Pharmacologist"

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1882.

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'1he sky's the hmit" for UB and Roswell Park's

1

new radiation oncology department

--

hen Kyu Shin, M.D., talks about 1nedicinc as his
mission, lle stresses that he was "taught to be a
good physician, not a just a good clinician." Th£
distinction, he says, is an imp01tant one. "Sometimes, tlte human factor is ~issing."

For l.he chatrman of l.he deparLment of
radiation oncology at a large medical school
and maJOr cancer center, l.he disuncuon
could eastly get lost in the technology.
Not so for Shm.
'" I regard medtcine as my mission not as my JOb," he says. "I like to use my
expertise to help l.hcse unfortunate cancer
patients.
"A good physician looks after patients.
It's not just 'nine to live' and then drop it.
lt's important. That's why I chose to specialize. I always feel if there's a need I will
be there."
Shin, who was recruned by UB and
Roswell Park Cancer Institute last year to
estabhsh a radtauon oncology program,
has filled such needs before - creatmg
preeminent radiation oncology departments at such presugtous msutullons as
the Cleveland Clinic and Lhe Tom Baker
Cancer Center m Calgary . Alberta, Canada.
He auns to do the same Lhmg for UB.
Roswell and the other consortium hospitals - and is well on l.he way, having
already introduced several innovauve treatments and applied for residency program
accreditation.
"This is really an exciting lime," Shin
says. "So many positive things are happening here. This is exactly what Dr. (Tho-

uons. Buffalo people always go elsewhere
to learn Now, they are coming here."
Part of Shin's efforts at establishing the
radiation oncology program at UB includes
building a residency program.
"We began l.he recruionent process for
a deparLment chair for radiation oncology
as far back as 1987," saysjohn Naughton,
M.D.. vice president for clinical affairs and
dean of the medical school. The department is new to UB, established after the
faculty council researched the program.
"Radiation oncology is seen nationally
as a separate residency program,"
Naughton explained. "Our policy is if a
program has independent status, we consider establishing a deparunent. Obviously, wil.h Roswell Park here, we should
take advantage of that."
Shm and his deparunent are now drafting curriculums for Lhe three-year residency program, scheduled to begin in
1993. The consortium program will also
train two post-graduate fellows. A clinical
traineeship was established last fall.
The department already provides major traming for Erie Community College's
two-year radiation therapy technician program, and works with both medical and
tugh school students during the summer.

mas) Tomasi (director of RPCI) and the
entire institute are trying to do - make
Roswell a leader on an international level.
~we can achieve that by having quality
programs, and we can actueve quality programs from a quality staff supported by
clinical research, patient care and education. And that is exactly what we have here.~
Shin doesn't conceal his enthustasm,
and it has spread throughout Roswell's
revitalized radiation oncology deparLmenL.
Since he arrived a year ago the department
has tripled the number of patients it treats
each day. last year, l.he radiaoon oncology
department logged 16,525 pauent visits.
The treatments offered are often the
~last resort" for some, proffered only after
ol.her treatments have proven ineffective.
One recent success, Shin notes, IS total
electron skin radiation.
~Treating the entire skin only IS a techUndergraduate medical teaching (as a
nical nighonare,~ Shin explatns. But with third-year student selective) has already
Roswell's new low-dose, computer-con- begun. "We intend to go into first and
trolled, after-loadmg system - the only fourth year selectives as we expand our
one in Western NewYork-Shinand hiS staffing,~ Shin said.
colleagues recently treated a patient from
Roswell's radiation oncology departSyracuse with mycosis fungoides whose ment has three divisions-clinical, medi"lesions are now completely gone. One of cal physics and radiobiology. "We have
the doctors from Syracuse came to team been able to recruit many new staff to
the technique," Shin relates, adding "we implement many new programs," Shin
have an obligation to teach other institu- says proudly. "The most important role

"RGOOD PHYSICmn LOOHS

RfTfR PRTifnTS. IT'S nOT

JUST \nlflf TO fiVf' RnD THfn
DROP IT. IT'S lfnPOfURnT..

�the University has played has been to
allow us to recruit a first class staff."
One of the most exciting new developments in the depanment is tts computer
netv,rork system, scheduled to go on-line
this fall. The program, which wHI be a first
in New York and probably m the U.S.,
Shin says, will completely automate all
patient record-keeping m the department
- from the time patients are referred,
through thetr treatment and to follow-up
back to the referring physicians. The
system will enable physicians to see patients, dictate findings to the computer
and send the results to the referring physicians by fax automatically.
"just imagine the dynamics of the referring doctors getting their mforrnation
the same day," Shin marvels. "Iu s a dream
come true." He envisions the system will
eventually be hnked wuh the Umverstty's
and other area hospttals' systems
Another mnovauon Shm has brought
to VB and Roswell tS stereotactic radiotherapy-"a prectSton bramsurgel') without a knife and without bleedmg," Shin
explains. The procedure, which uses sophisticated digitized computer targeting
and planning, "destroys the part of the
brain already destroyed by the tumor without any significant side effects," Shin says.
The noninvasive procedure, which can
be performed on an outpatient basis, is
used to treat a variety of benign and malignant lesions, including glioblastoma,
arterio-venous malformations, acoustic
neuroma, pituitary adenoma, craniopharyngioma, smgle metastatic malignant
tumors and solitary. base-of-the-skull
metastatic lesions. Most effective for the
treatment of target areas up to three centimeters in maximum diameter, the procedure giVes access to deep-seated lesions
which were formerly inoperable or reachable only by extensive surgery. Although
many centers in New York State are gearing up to do the procedure, Roswell Park
is the only one currently performing it.
Shin is characteristically already looking ahead. "We're now looking one step
further," he says, "using MR1 spectroscopic technology research to find out
exactly what happens metabolically when

8U,.P'AL0

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"IRfGMO mfOICinf HS mY miSSIOn
-noT HS mY JOB. IUHf TO USf
mY fXPffiTISf TO ~flP T~fSf
UnfORTUnHTf CHnCfR PHTifnTS.N

Kyw Shill, M.D.
patients are treated by means of
megavoltage radiation therap} How does
the tumor disappear? Can we predict the
radiation response by monitonng the exact metabolic changes? For the first time
ever," Shin says, "we may be able to explain why radiation works." Preliminary
research, he adds, has already begun.
Shin has a great deal of pride in his
department, in the University and in
Roswell Park Cancer 1nstitute. He is also

AND

BIONEDIC:At..

grateful for the support he has garnered
from each. and mindful the accomplishments realized belong to the
multidisciplinary environment that fosters innovation and quality patient care
and education.
"We are building a very nice department as a group and a family. And that is
possible because of Dr. Tomasi and Dr.
Naughton. This is an exciting time. The
+
sky is the limit."

SCt&amp;NTIST

SU""'WII."

1882

fJ)

�University at Buffalo med
students win •• I1Cifiotd
research awards
hree Umversny at BufTalo medical
students have won top national
research awards.
Arlene Lobo, a second-year student, was named a Howard Hughes
Med•callnsutute Research Scholar
at the National Institutes of Health from
the Howard Hughes Medical Institute in
Bethesda, Maryland
Yvette Vinson
and Andrea Williams, also both
second-year students, were selected as fellows in
Lhe Fellowship Pro- -=-,._..gram in Academic
Medicme sponsored b}
Bristol-Meyers Squibb Company and The
Commonwealth Fund. The fellowships
carry$6,000awards. Vinson received hers
for her "lnvestigauon of Haemopllilus
ducreyi" (memored by Michael A. Apicella,
M.D., professor of med1cme and microbiology); Williams received hers for her
"Nasopharyngeal colonizauon m otitis
prone and non-otHIS prone children"
(mentored by Howard Faden, \1.D., professor of pediatncs and co-director of the
divisiOnofinfectiousd~SCaseS).

+

Alums rjve back with
generous endowments
oscph A. Chazan, M.D., '60,and hiS
wife, Helen, have made a pledge to
the ~hool of Medicine and Biomedical Sciences' Pathways to Greatness Campa1gn. Their g1ft will be
used to endow the Dr. and Mrs.
joseph A. Chazan Scholarsh1p Fund es-

fl)

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~HVS ICI AN

tablished in 1985 to provide full tUition
scholarships.
Chazan is the 1991-92 national chairman ofUB'sAnnual Fund Drive He LS also
a member of the medical school's Advisory Board.
Paul K. Bin ch, M.D.;43, chmcal associate professor emeritus of gynecology
and obstetrics, has made a gift of$1 00,000
to the medical school to endow the Paul
Binch, M.D., Endowment Fund. The
fund will provide general suppon for research, visiting speakers, equipment and
scholarships in the field of reproducuve
endocrinolog} .
+

C. K. Huang honored at

annual medical school
faculty meeting
ix faculty members, e1ght r~1dem
physicians and the director ofUB's
Health Sciences Library were honored june 3 at the annual faculty
meeting of the School of Medicine
and Biomedical Sciences.
C. K. Huang, director of the UB Health
Sciences Library, received the first john
and Margaret Naughton Special Recognition Award. Naughton, vice president
of clinical affairs and dean of the med1cal
school, and his wife established the award
to recognize significant comnbuuons to
the advancement of the medical sc hool
by a staff person or member of the community.
Huang, library director smce 1970, IS
credited \\ith bringing nauonal recogmtion to the library for its mnovauons and
SCT\'!ce. He is a fellow of the Upstate and
Ontario Chapter of the Medical Ubral"}
Association and a distinguished member
of the Academy of Health Informauon
Professionals.
Robert A. Klocke, M.D., professor of
medicine and physiology, rece1ved the

AND

B

IO

MCO

IC

AL

~

Stockton K1mball
Award for excellence in academic
achievement. The
award recognizes
contributions to
research, teaching
and
service.
Klocke, chief of
UB's Pulmonary
(. K. Huang
Division, is also
editor of American
Review of Respiratory Diseases.
He Vl-'ill deliver the
Stockton Kimball
lecture at next
year's
annual
meeting.
Milford
C.
Maloney . M 0
Robert A. Kladte, M.D.
clinical professor of
medicine, received
the fourth annual
Robert S. Berkson
Memorial Award in
theArtofMedicinc.
The award recognizes excellence in
patient care and
teaching by volunteer faculty.
Robert J. Ge11&lt;o, D.D.S.
Robert]. Genco,
DDS., Ph D., distinguished professor
and chair of oral biology in the School of
Dental Medicine, was the first person
outside the medical school to receive the
Deans A\\ard for outstanding leadership and academic excellence. While
noting Genco's numerous contributions
to the health sciences at the univerSity,
the dean lauded him in particular for
assuming the mterim chair of the medical school's Department of Microbiolog} wh1le mainLaining his demal school
responsibilities.
Louis A. and Ruth Siegel Teaching
Awards were presented in four categories:

'

Q

Q

2

�•
pre-clinical, for basic sciences teaching;
clinical, for in-hospital instruction; volumeer, for unpaid faculty, and house staff,
for resident physicians. Winners were
selected from nearly 200 faculry nominated by students.
The recipients were:
.,;. Alan Lessc, M.D., assistant professor of pharmacology and therapeutics,
pre-clinical category. Lesse also won this
award in 1990.
-.r Fred Luchette, M.D., assistant professor of surgery, clinical category.
Luchette also won this award in 1990.
-.r Steven lana, M.D., clirucal assistant professor of pedtatncs, volunteer
category.
-.r Alon Coppens, M D., radiology;
Kathylynn Pietak, M.D., med1cme;
Ramanathapur Natesha, M.D., surgery;
Bruce Solomon, D.O., neurology;
Mattheos Falagas, M.D., medicine;
Siddhartha Shah, M.D., medicine;
Edgardo Salvador, M.D., medicine, and
Dawn Hrab, M.D., med1cme, all received
house staff awards.
+
B

Y

LOIS

BA

Thomas F. Frawley,
M.D., "44, chairman of
Graduate Med1cal Education. St John's Mercy
Medical Center, Emeritus
Professor of \fedicine. St.
Louis University School
of Medicine, St. Louts,
Missouri, and national
chairman of the UB medical school's 1991-92 Annual Fund, "''as inadvertently omiued from the list
of members of the James
Piau White Society in the
Winter 1992 cd1tion of

Buffalo Physician and Biomedical Scirnlisl.
+

KER

Match Day 1992: most
UB med students get
their top choice
atch Day - that nail-biting
time when fourth-year medical students learn where they
will spend the next three years
as resident physicians- was
overwhelmingly successful
this year for UB's medical students as 84
percent of them received one of the1r top
three choices.
Sixry-eight percent of the 141 students
who participated received the1r topch01ce.
10 percent received their second choice
and 9 percent received their third cho1ce
Eight percent were unmatched. In addition, six military matches were made
Although a majority of the students (56
percem) will venture out of state for the•r
residency training, a full 25 percent of
UB's medical students will remain in Buffalo and take their training at the Graduate
Medical Dental Education Consortium
of Buffalo.
+

�[1]

. . . . . . . . . . . . . . . . . . . . . . . . . . . .. . . . . . . . ..... . .. . . . . . .

~

I

Medical school alunri
feted at receptions
in Florida cnl Indiana
he University at Buffalo's medical
school recently honored its graduatesatalumnieventsheld in Florida
and Indiana.
Florida alumni were feted at
two separate receptions in February. William Boardman, M.D., '44, and
Barry Weiss, M.D., '67, hosted a reception
in Tampa at the Westwood Hyatt whtle
Thomas Rodenberg M D , '51 , and his
wife, joan, hosted East Coast alumni at
the Tower Club in Ft Lauderdale.
Alumni from various classes attended,
mcluding Thomas Bumbalo. MD . '31 ,
and hiS wife, Ednh Bumbalo's grandson,
Thomas Bumbalo,jr., tS a member of the
medical school's Class of 1992.
Also in February, George Ellis, M.D.,
'45, hosted a luncheon at the Radisson
Plaza Hotel in Indianapolis, Indiana. Thomas Riemenschneider, M.D., M.B.A. , associate vice president for
clinical affairs and associate dean of the mcd1cal
school , discussed the
Western New York
Health Sciences Consortium and the lnformaoon Network System that
will soon lmk the medical school with its affiliate hospitals and rural
health care sites.
On hand at the
events
in
Florida was
john Naughton, M.D., dean
of the medical
school , who
spoke about the
many new developmentsand

II

programs currently underway at UB.
1 aughton told the groups about the construction of the new biomedical research
complex to be completed in 1993 and the
Western New York Health Sciences Consortium and its Information Network System. He also talked about the continued
recruitment of some of New York State's
most talented students and UB's unique
uclassroom without walls" clinical training setting.
+

Medical school begins
department chai' secl'ches
earchesare underway for the cha1rs
of two clinical departments and
one basic sc1ence department m
the School of Medicine and BIOmedical Sciences.
Department heads are expected
to be chosen toward the end of the summer for the departments of anesthesiology, radiology and biochemistry, accord-

mg to john Naughton, vice president for
clinical affairs and dean of the medical
school. ~we have outstanding candidates
for all posts," a ughton said, adding that
UB has been able to attract well-recognized academics of national prominence
vying for the positions.
In addition, search committees have
been formed to chose the city-wide head
of cardiOvascular surgery and the director
of the Dent Neurologic Institute. aughton
said several prominent prospects are in
the running for the cardiovascular post,
wh1ch is expected to be filled by the fall.
The post at the Dent will be filled next
summer.
+

UB med student selected
for Ameriam Meclcal Student Association felowslip
hristopher Wood, a second-year
medical student at UB, has been
selected to participate in the American Medical Student Association
Foundation's Washington Health
Policy Fellowship Program
(WHPFP).
Wood isoneoflS
medi cal students
chosen for th1s
summer's fellowship
fromapoolof74cand!dates. The fellowship is associated with
thiS summer's American College of Prevenuve Medicine.
In its founh year, the Washington
Health Policy Fellowship Program IS
designed to introduce promising
medical student leaders to the health
policy process, current topics in
health policy and their role as advocates. The program combines an orientation and weekly seminar &lt;;f'ries
with a field placement experience.+

�[I]
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he School of Medicme and Biomedical Sciences graduated Its
146th class during ceremonies held
in May. Here, fnends and families
celebrate with the graduates as they
receive their degrees.
The Class of 1992 includes 150 students- 146 who earned medical degrees
and four who earned combmed M.DJ
+
Ph.D.s.

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�Alunri meet il Apri for Spri1g
Ciicm Day cnl Reurion Weel(end
he School of Medicme and Biomedical Sciences held tts Spnng Chmcal Day and Reunion
Weekend on Apnl 25. The events, which
included a day-long seminar and cocktail receptions, were well-received, as evidenced by
thts photo montage.

BU
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1992

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�CLASS

OF

1942

~ First row, left to right: George L Eckhert,
Richard Mnauo, Vincent Cotroneo, Howard
Frederickson
~ Second row: Urban L Throm, Richard Ament,
Boris Marmolya, Charles A. Baudo, Ivan Bunnell, J.
Walter Knapp
~ Third row: Richard Jones, Kent L Brown, Francis
Clifford, Vincent Parlante

CLASS

OF

1947

~ First row, left to right: Frecleridt Whiting,
Wilrtom S. Edgecomb, Robert M. Jaeger, Hans F.
Kipping
~ Second row, Robert Ehrenreidt, Wil~am C. Baker,
Wilrtam M. Bukowsk~ Arthur J. S&lt;haefer, Ridlard J.
Kenr.ne
~ Third row: Ferdinand Paor.n~ Robert J. Dean.
Russell J. Sacco, John B. Sheffer, Carl J. Nicosia,
HenryS. Gardner, Daniel R. Curtin. James F. Stagg,
Peter J. Jurtan, Elbert Hubbard

CLASS
~

OF

1952

First row, left to right: Colin C. Madead, Eugene
Sigman. Kenneth Altshuler, Barbara G. Coriey, Burtoa
Stulberg, Donald F. Doha
~ Second row: John J. Banas, Aaroa Simpson.
Robert A. Baumler, Alvin J. Brown
~ Third row: Roy J. Thu111. Kurt J. WegDer, Oliver
J. Steiner, Vidor Panaro
~ Fourth row: James N. Schmitt, Bernie P. Davis,
Bruce F. Connell. Alfred Lmarus
~ Fifth row: Donald J. Spredter, Eugene W. Loeser,
Wilbur S. Schwartz, John Y. Rllllchoff, Travers
Robbins, Ralph M. Obler, Neal W. Fuhr

�··········································································· · ···················· ~all

•
CLASS

OF

1957

..,. First row, left to right: Btn Celnilter, Robert B.
Sussmcm, Sol Messinger, Arthur L Btdt, Ross
Marltello, Frank J. Chafel
..,. Se&lt;ond row: Herbert Metsch, Robert Carpenter,
Donald R. Hauler, Sherman Woldmon, Joseph I.
Schultz
..,. Third row: Paul Archambeau, Edward
Welsenheimer, Bronson Berghorn, Charles F.
O' Connor, Richard F. ~iller

CLASS

OF

1962

..,. First row, left to right: Charles G. Adams, Ronald
Dozoretz, Joseph P. Amenia, Josepla R. Gerbas~ Paul
J. LorH
..,. Se&lt;ond row: Robert G. Ney, Morton E. Wei&lt;hsel.
David E. Carlson, Phitlp D. Morey, George R. Tzetto,
Sebastian FasaneUo
..,. Third row: Seth A. Resni&lt;off, Owen G. Bossman,
Alan L Pohl, Morlt Peter Heilbrun, Morton P. Klein,
Melvin J. Steinhart, Joseph A. Cimino, Roberto J.
Gnbert, Anthony Morkella, Robert Goldstein, Harold
Brody
..,. fourth row: Jack C. fisher, Philip Weisinger,
Gerald Patterson, Martin F. Abbert, Oscar
Oberkircher

CLASS

OF

1967

..,. First row, left to r¥rt: Jonathan ~ J. Brian
Sheedy
..,. Second row: David C. Stephens, Barry M. fpstein,
Barry M. ~ Thomas P. Sheehan, vn&amp;c.n Burie9l,
Lon C. Ouem:Jer, John P. Kely, Docdd l Mler
..,. T1Wd row: David FugcrnoHo, Jacob Kritemc~~~, Arthur
C~ Ronald Josephson, John B. Keiser, Robert M.
Benson, Douglas M. Sirlti1, Trevor Robinson, David R.
Dantzker, James Gicrirone, Ridtard Judelsohn, Thomas
Augustine, Robert J. Brown, George S. StilT
.... Fourth row: F11111kln H. Splm, Arthur C. Sosis, David
L Larson, Norman Berltowih, Anthony l.oGallo, Cart W.
Ehmann, IInKe Etmger, Alan R. Salmnan, Rocco C.
Vetwto, Thomas O'Comor, Douglas Gerstein, Arnold Z.
Gold, John J. Teanor, Midtoel !'haps

�CLASS

OF

1972

..,.. First row, left to right: Martin T. Hoffman,
Steven J. Rosansky, George E. Lundgren. Ywginia F.
Howley, lon M. Frankfort, Robert fmhorn
..,. Se&lt;ond row: George Kotlewsk~ Ridlard S.
Goldman. Martin Brecher, Edwin A. Salsitz, Richard
A. Savage, Stephen J. levine, Murray A. Morphy

CLASS

OF

1977

..,.. First row, left to right: AntoineHe Wozniak,
Chem1 A. Thorpe, HelenS. fmdlay, Nedra J. Harrison.
Undo L Benjamin
..,. Second row: Albert Sddisserman. Carl J. Schmi«,
Thomas H. Botsford, Alan S. Kuritzky, Dirk H. Dugan.
Richard P. Newman. Joseph Byleby~ Reginald B.
Stdes, Eugene A. Paul

CLASS

OF

1982

.... frst row, left to r9rt: Men CJtuns. waam
Schedrter, £Jon Healy, Pilip Steget~~C~~~n. tmo
RIDnowitz, Bet+nin Confesso, Y~rginio Keane, Joseph
P. leberer, Ancho Abati-Scon, Debbie L K~
fhabetla Bartog, Nancy Peters, Susan fasd!beck. Richard
A. WoH, David I. Kuru, Joseph F. Gioia, Gen*l F. Ylfale
..,.. Second row: Jessial Roc:kwel, Robert ~
Stephen Donovan, Robert C. Thomas, Potridl T. Hurley
..,.. T1n row: Michele Leon, An«ew R. Hordes, Robert
P. Dudek
..,. Fourth row: Marcia McAvoy, Gerold A. Hinter,
Joseph Gelonnini
..,. fifth row: Mary ASce Kely, Kevil J. Bartog, Joseph
T. Wayne
..,. Sixth row: Eliot Chartash, David Weldon, Michael A.
Cesar, Ivan A. Bcalmwel, fmotlay Geemg

�CLASS

OF

1987

..,. ftrst row, left to right: Camille Buonocore,
Marina Cotto, Patrick Shaughnessy, Jennifer Cadiz,
Bonnie Orzech-Mixon, Kevin Quinlivan
..,. Second row: BrU&lt;e Mac:KeUcr, John O' Brien,
Thomas Smith, Michael Rudnidt. JiB Koehler, Timothy
Bukowski, Douglas Katz

TWs sigaecl origillal
of a po&amp;tical

Dr. &amp;ush finally arrives
YE:.S, I
BELIE.\/~

IT
IS A Rt.ct.SSION...

c.tooa, •Dr. Bnh
finaly arrives,"
donated to tlte
medical school by
Plllitzer Prizewinning Buffalo
News cartooftist
Tom Toles, was
won by Robert
Reisman 'S6 in a
siletlt auctiall held
d.ring spn.g
Oilical Day.

�•
1

··························································································

-

I

9

3

0

cology at the Umvef!&gt;ll}' of Pillsburgh C.Chool of Medic me.

5

MAURICE B . FURLONG '35, of
jame:.town, New \ork mforms
us that hts book, How To Gtt rour
Baby To 5/tep, ha!&gt; JUSt been published.
A VROM M . GREENBERG '36,

of Tucson, Arizona. was named
Phystctan of the Year by the Ptma
County Medtcal Society. Hts hfe
story. "Reflections of an Old Curmudgeon.~ was featured m the
Februarv pubhcauon of the
Societ\ .

1

9

4

0

5

W . WILLIAM TORNOW '4 6 , IS

pre:.tdent of the Hobart Club of
Buffalo and mus1c eduor of a
weekly newspaper, "The
Southtowns CitiZen." Tornow tS
an assistant chnical profes.sor of
medicine (pcdtatrics) at the Umversity at Buffalo School of 'vi edtcine and B10medtcal Sciences.

1

9

5

0

5

ROBERT E . PLOSS '5 1 , writes,
"Iam ahve and well after the Oakland firestorm of October 20.
1991, that burned m~ home to the
ground along \\ith 3,000other!&gt;. I
w1ll rebutld."
ANTHONY P

SANTOMAURO

'56. was elected a delegate from
the State ~ledtcal SoCiety to the
house of delegate!&gt; of the Amencan Medical As&lt;,ocmuon A past
pres•dent of the ~1edtcal Soctety
of the County ofEne. he current!\
serves as a representative from
Western ew York on the Council of the Mcdtcal SoCiety of the

wntes,
"After two \·ear!&gt; of pcdiatnc residency at The Chtldren's llospttal
of Buffalo, I transferred to a surgery residenc&gt; at the Eastern Yirgmia Graduate School of "v1edtcme m Norfolk. Vtrgmta Presently I am a second year resident
insurgef). I have JUSt matched for
a plasuc surgerv restdenc} at the
Pennsylvania State Umver!&gt;llY beginmng in 1993.
JOHN S . AKER '88,

John S. Alter '88
State of '\ew York. He is a member of the board of directors of the
.\.1edtcal Uability .\.1utual Insurance Company and IS a member
of the State ~1edtcal Soctety'sState
Legl!&gt;lanon Commmee. He tS also
an officer of the E•ghth OtStnct
Branch "v1ed•cal Society which
comprises the eight Western New
York counues.

1

9

7

0

5

H UGH A . SAMPSON 75, was
recently promoted to professor of
pedtatrics at Johns Hopk•ns Universll) He is co-editor of the new
JOUrnal, Pedimric Allerg&gt; and lmmunolog&gt;. and co-editor of a book.
Food A/lug&gt;. published by
Black\\ell in 1991.

1

9

8

0

5

ARLENE ROSE CURRY '82,

and her husband.john Hntes, are
the proud parentS of a baby gtrl,
Alyssa Rose, born Januaf) 20,
1992
CHERYL A . KUBISTY '86, tSan

J!&gt;ststant professor of medtcine in
the Center for Clinical Pharma-

A

N

0

B

tO

M

NARINDER SHALLA '88.15 now

chtef restdent of mternal medicine at '\ew York Umver!&gt;ll}'. He
and hts wtfe. \1arva KaltSh. announce the bmh of a daughter.
Son) a Shalla, on june 30. 1991.
CLIFTON WOODFORD '88 ,

vmtes, "I've been in San Otego for
two years takmg care of dtvers
and submarmer&lt;,. We (my wire
Kelly and three chtldren) wtll be
here ror tWO more years while I
complete m\ medtcme restdency
at the San Otego 'laval Hospttal "

RusseU Van Coeveriag II, ' 77
OBITUARIES
ROY E . REED '32, died sudden)} or a heart attack on Februaf}' 2. 1992.
MELBOURNE LENT '4 3 , dted
Apnl 11. 1992. after suffenng a
heart attack.
JOSEPH A . VALVO '4 3 , died
on March 13. 1992. in Pinehurst,
North Carolina.
R OY S WARTOUT Ill '4 5 , died
of cancer onjanuaf)' 1, 1992, m
Temple City. California.
RUSSELL VAN COEVERING II ,

1

9

9

0

5

MATTHEW J . CYWINSKI '91 ,

'77. rued unexpectedh on May 2,
1992

rnamed Bonme Zmuda on Februaf} 29, 1992. He tS a general
surgef)' hou!&gt;C offtcer at Hen'}
Ford Hospual. Dearborn ,
\11chtgan.

Call for nominations
Don·t forget to cumplete and matl the attached postcard for
OtStmgUtshed Medical Alumnus/a Award. Nominations will
be accepted unul March I, 1993.

C:OICAL

SCtlrHTtiT

1

9

g

2

�I

:

�Buffalo, NY
Permit No. 311

1773

HEALTH SCIEf.tCES

SERIALS DEPT
ABBOTT HA-L
CAMPUS f·A:L
4

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                    <text>�BUFFALO PHYS I C I AN

Volume 26, Number 4
EDITOR

Nanette Tramont Kollig, R. N
ART DIRECTOR

Alan J. Kegler
ASSOCIATE ART DIR E CTOR

Scott Robert Fricker
STATE UNIVERSITY O F NEW
YORK AT BUFFALO SCHOOL
OF M E DIC I NE AND
B I OMED I CAL SC I ENCES

Dr. John aughton, Vice President for
Clinical Affairs, Dean
ED I TOR I AL BOARD

Dr. J ohn A. Rtchert, Chairman
Mr Ric hard de Asia
Dr Martm Brecher
Dr Harold Brody
Dr. Rtchard L. Colhns
Dr. Donald P. Copley
Dr. Alan J Dnnnan
Dr. Ttmothy Gabryel
Dr. Glen Gresham
Dr. Charles Massa ro
Dr. Charles Paganelh
Dr. Luther Robmson
Dr. Thomas Rosenthal
Dr. Saleela Su resh
Dr Bradley T Truax
Dr. Ste phen Spauldmg
Dr Jerome Yates
TEACHING HOSPITALS AND
LIAISONS

Batavia VA Medtcal Center
Buffalo General Hospttal
Michael Shaw
Buffalo VA Medical Center
Paula Pedene
Children's Hospttal of Buffalo
Ene County Medical Center
Mercy Hospital
Millard Fillmore Hospitals
Frank Sava
Roswell Park Cancer Institute
judith Rice
Sisters of Charity Hospital
Dennis McCarthy
© The State Umversity of New York at
Buffalo

Buffalo Phvsicwn is pubhshed quarterly by
the State UmversnyofNew York at Buffalo
School of Medicine and Biomedical Sciences and the Office of Publications. It is
sent, free of charge , to alumni , faculty ,
students, reSidents and friends . The staff
reserves the nght to edit all copy and
submissions accepted for publication .
Address questions, comments and submissiOns to: Edttor, Buffalo Phystcian, State
University of New York at Buffalo, University Publications, 136 Crofts Hall , Buffalo,
New York 14260
Send address changes to: Buffalo Physician, 146 CFSAddition , 3435 Mam Street ,
Buffalo, New York 14214

Dear Alumni and Supporters of the UB Medical School:

T

he medical school and its teaching hospitals together with the faculty have made a
major commitment to promote the education and training of an increased number of
generalists for Internal Medicine, Family Medicine and Pediatrics. Throughout the
past year, significant changes and accomplishments have been made in the governance
of the graduate medical education programs and a mandatory two-month long clerkship
has been initiated in comprehensive ambulatory care education.
Through the recently funded Reimbursement Demonstration Project, six coordinated
projects in primary care were funded together with a major project in geriatrics and
minority recruitment and retention. These changes have positioned the medical school
to address needed reform in undergraduate medical education. While some changes are
already planned, UB has applied for a major grant for the training of
generalists from the Robert Wood johnson Foundation. The school
was visited by an external review committee in july, and we hope to
be membered among the 18 awardees when the Foundation announces its choices in mid-November. The next challenge will be to
compete successfully to be one of the l2 schools funded for a period
of five years commencing in mid-1994. These two initiatives are
accompanied by another complementary award. Dr. Thomas
Rosenthal of the Department of Family Medicine was a successful
winner of a major five-year grant from Health Resources and Services
Administration to study the ways in which to develop and promote primary care in rural
areas.
I hope you are pleased by the commitment to this needed part of medical education and
care that UB has made. We will keep you posted on the school's progress in this important
area in the years ahead.
Sincerely,

john

aughton, M.D.

Vice President for Clinical Affairs
Dean, School of Medicine and Biomedical Sciences

Dear Fellow Alumni:

T

his is the ~ear of Professor William Greiner's inauguration as the thirteenth president
of the Umversny , an ausptc~ous event for those of us who support the continued
growth and ~ttahty of our medtcal school. Prestdent Greiner has long been a friend of
. the_ bwmedtcal soences and has been conststently vigorous in his support of our
objectives. For example, Prestdent Gremer and Dean john Naughton recently announced
a target of 50 percent pnmary care phystctans by the graduating class of 1995, thus placing
us m the vanguard of Amencan medical schools in meeting our
country's health care needs.
Your Alumni Association has presented the Distinguished Medical
Alumnus Award to Dr. Alfred Evans, Yale Emeritus Professor of
Epidemiology and UB Class of 194 3. We have also met our Rochester
alumni at the Richardson Canal House for an informal renewal of
friendships. Support for our current medical residents has continued
wtth another "Prep for Practice" seminar. Our Community Physician
t.
for
series on career choices has reached many students p
· c1· · 1D
d
. repara wns
Spnng
.
t_mca ay an Reunion Weekend are well underway toward
· n
a hvely
program abou t phystctan
.
.
. . performance and competence . 0 ur c1ass reumo
to
organize
spring
reun
d
1
·ft
chatrmen. have been workmg dthgently
· 0 n d.
1
. .
mners an c ass gt s.
We cenamly have reason for pnde m our school and its successful alumni/ae!
Yours truly,

Don Copley, M.D., '70

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Research
Hospital News
The Graying of Medicine e Changing the practice of
medicine to meet the challenges of a burgeoning
elderly population.
Rehabilitation Comes of Age e UB's new Center helps
an aging population reclaim its lost abilities.

UB' s new SS million
demonstrotion project to
eose the primary care
shortage could become a
model for the nation.
Page 26.

Conquering Ojos del Salado • UB's William Carl, D.D.S.,
on his mountain-climbing adventure in the Andes.
UB medical
students wm
soon see
patients who
aren't really
sick at all.
Page 28.

, Medical School
People
Alumni
Classnotes

*[limning

t~e secono·

~ig~est eleuation int~e

Western ~emisp~ere.
Harold Brody steps down as chair of anatomical sciences after over two
decades. Page 30.

~age 1~.

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UB-NASA experiments yield
unexpected results
n experiments with potentially far-reaching
ramifications for the U.S. space program,
University at Buffalo scientists have
found that the human body regulates the
cardiovascular system in a totally unexpected
manner in the weightless environment of space and
takes at least a week to return to normal functioning
after even short flights.
The cardiovascular research, conducted
on NASA's first Spacelab Life Sciences
Mission last june, showed that astronauts
could not perform some routine tasks at
their full capacity for the first days after
returning to Earth. And in what the researchers term the most surprising finding
of the study, results showed that in space,
the human body uses a previously unobserved mechanism to regulate the cardiovascular system.
David R. Pendergast, Ed. D., professor of
physiology and one of the investigators,
presented the findings at a special two-day
meeting on cardiovascular response to
exercise sponsored by the American Heart
Association in Chicago injune.
The experiment, funded by a $2.3 million grant from ASA, was developed by
Leon E. Farhi, UB distinguished professor
of physiology. It was one of three studies
on the mission focusing on astronauts'
cardiovascular function in zero gravity
and under normal gravitational forces once
they return to Earth - the first comprehensive human cardiovascular experiments conducted in space.

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"These results will change the way ASA
isthinkingabouthumansurvivalinspace,"
Pendergast said. " ASA had thought man
could adapt readily to problems of space
flight. This research shows that some
functions remain compromised to some
extent for at least seven days after a short
flight.
"This was only a nine-day flight,"
Pendergast added. "On a much longer
flight, the effects could be much more
pronounced, or last considerably longer."
The project was designed to determine
how the heart and lungs perform during
weightlessness, and after adjusting to that
environment, how they function when resubjected to Earth's gravity or a stronger
gravitational force.
This knowledge is important, Pendergast
.
explamed
because the success of future
'
. depen d on the travelers'
space travel Will
.
.
. norma lly during travel
ab1hty to funcuon
.
as well as when they reach their destma· anotherplanet
tion-beitaspacestauon,
or Earth.
, mechanisms and neural
"Our bo d ys
d
reflexes are esi·gned to control blood

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pressure
at 1-G ,"
Pender-gast said. "One of the major
concerns regarding the body's adaptation
to space flight is that the adjustments the
cardiovascular system makes during flight
to maintain blood pressure in weightlessness may compromise its ability to readjust to gravity upon return."
UB researchers, using equipment engineered by UB technicians Richard A. Morin
(U.S. . ret.), Christopher G. Eisenhardt
and Claude Miller, took readings of three
astronauts' cardiac output, oxygen consumption, mean blood pressure and heart
rate five times during the six months before the flight. They calculated stroke
volume, total peripheral resistance and
the amount of oxygen extracted from the
blood.
The astronauts conducted the same experiments during the nine-day space flight,
and UB researchers took readings again on
the first seven days after the astronauts
returned, as well as on the 45th post-flight
day.
Cardiac output was expected to increase initially in space, and then drop to
normal in the weightless environment, as
it does in experiments conducted on Earth
under simulated weightlessness. During
space flight, however, cardiac output went
up and stayed up.
When cardiac output increases, the body
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1'3

.~
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attempts to maintain blood pressure; previous experiments had suggested the body
reduces the amount of plasma in the
blood to regain cardiovascular balance,
freeing up water from the plasma and
eliminating it in the urine.
But because cardiac output did not
come down in space and blood pressure
remained stable, the researchers speculated a previously unobserved adjustment
mechanism was apparently at work. And,
in fact, calculation of the other cardiovascular variables showed that in space, the
body had maintained blood pressure
through hyperperfusion- engorging organs and tissues with blood.
"This type of regulation of blood pressure was completely unexpected ,"
Pendergast said.
"The
system's failure to
reduce cardiac
output and its
ability to accept
the
hyperperfusion are hard
to reconcile
using current
physiological
thinking."
The researchers
now theorize that
this phenomenon
is at the crux of the
cardiovascular
difficulties astro-

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reentering gravity. It will be the central
focus of their research on future space
flights.
Post-flight data showed the ability of
astronauts to perform work was severely
limited immediately after leaving the
weightless state and reentering gravity.
"On the day they returned, the cardiovascular system was very compromised,"
Pendergast said. "Stroke volume was
low, heart rate was high. The system was
trying to compensate for the stress of
gravity, but it couldn't.
"By post-flight day one, the astronauts
were able to perform exercise, but the
body was not stable. They could do 30
minutes of exercise but the body was
stressed. They couldn't have done more."
The astronauts' ability to respond to
stress remained compromised
for seven days.

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"This is a significant problem that needs
to be corrected if we are serious about
longer space flights," Pendergast said.
"Some more creative thinking has to come
into play."
All readings were back to normal by the
45th day.
Pendergast praised the astronauts for
their skill in conducting the experiments
under demanding conditions. 'The crew
did a phenomenal job getting data," he
said. "It's an incredible testament to what
humans can do."
UB researchers have already begun training more astronauts to perform the same
experiments on a Space Shuttle mission
tentatively scheduled for next summer. +
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Area's first ECMO opens
at Children's Hospital

. . . . . . . . . . . . . . . . . .. .

mained on ECMO for six days and finished recovering in the hospital until he
was able to go home several weeks later.
As many as one in every 4,000 to 5,000
newborns could benefit from the treatment, according to Robin Steinhorn, M.D.,
director of the ECMO Center. "With the
establishment of an ECMO Center here at
Children's we're taking on the challenge
of caring for these desperately ill babies.
We hope to be a resource for the local
community as well as the entire state,"
Steinhorn said.
+

he Children's Hospital of Buffalo
has opened the area's first extra
corporeal membrane oxygenation
(ECMO) service.
Open since late june, the ECMO
Center is one of only two in the
state (the other is at Columbia Presbyterian Medical Center in ew York City).
The state-of-the-art heart-lung machine,
used for infants and children with lifethreatening lung or heart failure, completely takes over heart and lung function,
enabling the patient's heart and lungs to
rest and recuperate on their own.
Housed in its pediatric intensive care
unit, Children's ECMO service is manS Senator Alfonse M. D'Amato
· ·
aged by an interdisciplinary team consistrecently
announcedthattheSening of an ECMO physician, coordinator,
ate VAIHUD!lndependent Agen.
. tions Subcommlttechnician, pediatric surgeons, attending
cies Appropna
tee has approved his request for
physicians and pediatric intensive care
.
to renovate The
nurses. The unit's first patient, a newborn
$2 m1.11 wn
.
.
of
Buffalo's
Regional
1
with sepsis, was placed on ECMO within Children's Hosplta
.
his first 18 hours of life. The infant re- Pediatric Intensive Care Umt.

.

. .. . . . . . . .. . . . . .. . . . . . . . . . .

"Children's Hospital is
a national leader of health
care for our children, providing cutting-edge scientific discoveries and stateof-the-art medical treatments for seriously ill and
injured children, regardless of their ability to pay,"
said D'Amato.
"Our children deserve
the very best health care
available. These funds will
ensure that the badly
needed renovation of the
PICU will go forward
without delay to provide
for the health care needs
of the community's families."
Work on the $8.7 million renovation is scheduled to begin next year, pending approval
by the State Department ofHealth's Office
of Health Systems Management and the
completion of additional fundraising efforts.
The project includes expanded space
for each PICU bed, expanded isolation
rooms, enhanced nurses' and physicians'
stations, an on-site satellite pharmacy and
laboratory and enhanced storage and ad+
ministrative space.

$8.7 mORon renovations
proceed at Children's

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Legislature authorizes
funding for RPCI maior
modernization proied

tion of a pedestrian
walkway system to unite
the campus;
replacement
and modernization of inpatient beds;
correction of
life safety ,
health code
and infrastructure deficiencies ,
and restoration of structured parking.

he New York State Legislature last
March passed legislation that would
authorize bonding for a major
modernization ofBuffalo's Roswell
Park Cancer (RPCI) Institute.
Thomas B. Tomasi, Ph.D., M.D.,
RPCI president, said he felt tremendous
"relief, elation and gratitude" as he watched
ew York State Governor Mario M. Cuomo
sign the bill which would appropriate
$241.5 million to rebuild the nation's oldest cancer center. "Relief," he said, "because we had won a long hard fight. Elation because we had taken a giant step
toward accomplishing what we had set
out to do. And gratitude to the many
individuals whose response to "it can't be
done" was always "it will be done."
Roswell Park's current campus comprises 19 buildings with approximately
one million square feet on 25 acres. The
major modernization program calls for
the construction of a new diagnostic and
treatment center for radiation therapy,
diagnostic imaging, nuclear medicine and
surgery with its related post-anesthesia
care unit and central sterile supply. Construction of the center will begin next
year, with completion scheduled for early
1996.
A new vivarium - which would centralize disparate animal facilities presently
spread over five buildings on campus and
two off campus - will be completed in
1995.
The plan also calls for the construction
of a new laboratory building and renovation of other laboratory space to remediate
obsolete mechanical and electrical systems and to provide additional space to
meet the needs of the institute's basic
science programs.
Other priorities include the construe-

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The legisla- Artist's rendering of Roswell Park Cancer Institute's major modernization.
tive
bill
passed in March, which is the final legisla- delays in renovations required to repair
tive approval required before the project its deteriorating infrastructure, correct
can commence, also authorizes the estab- code deficiencies, support competitive
lishment of a Roswell Park Practice Plan to programs and facilitate recruitment, were
enable the institute to add 30 new physi- chipping away at the institute's oncecians over the next few years without solid reputation as a major national canincreasing state funding. It will also pro- cer center.
vide opportunities to develop joint venCuomo made a commitment to reverse
tures with other health care facilities , in- these trends and pledged in 1989 and
cluded Roswell-owned and operated fa- again in 1991 to do "whatever it would
cilities outside the Buffalo area.
take" to modernize the Institute.
Funding for the project, which took
The major modernization formally beyears to obtain, began in 1984, when gan in 1989 when a team of architects,
Cuomo appointed a Blue Ribbon Com- planners, engineers and market and fimittee to assess conditions at RoswelL nancial analysts headed by Bohm • BBJ
The committee stressed the national im- was selected to conduct the planning
portance of the institute's scientific and project. An interagency core committee
clinical programs, but underscored the of key management from the Institute,
critical need for capital improvements to the Department of Health, Office of Genthe physical plant it found fundamentally eral Services and the Dormitory Authorinefficient and dehumanizing.
ity was established to review and approve
In the past, Roswell Park- part of the the plan in progress.
ew York State Department of Health
The combined direct and indirect ecosince 1911 - received approximately 45 nomic impact of Roswell's major modpercent of its funding from the state. ernization program on Western New York
Today, the institute receives less than 30 is estimated at $511 million, with over
percent from ew York State. That, plus 5,000 new jobs expected to be created. +

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s the baby boomers age, a demographic tidal wave will reshape the structure and culture of
medical care for the elderly Already, physicians are learning to care for an older populationsome of whom are astonishingly able while others are remarkably frail- that is relatively new
on the planet. Human life expectancy at birth has virtually doubled since the mid-19th century
from 40 years to near 80.
In fact, since 1900, the number of Americans 65 years and older has grown tenfold, from 3.1
million to 31 million today By the year 2040,68 million people will be older than 65, an estimated
22.2 percent of the U.S. population at that time, as compared with 12.5 percent now.

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�ere, more than 15 percent of the community is 65 years and older,

A preview of the medical community's competitive grant process.
The program emphasizes clinical trainresponse to the nation's aging population
maybefoundinWestem ewYork. Here, ing, aughton says, because, "The most
more than 15 percent of the community is effective part of our education is the in for65 years and older, approximating the ratio that will prevail in the country as a whole in
another 15 years. Responding
to the needs of this community, the University at Buffalo
School of Medicine and Biomedical Sciences is taking a
leadership role in training physicians to respond to the needs
of older patients.
This year the medical
school initiated a three-year
trial program, the Indirect
Medical Education (I ME) Demonstration Project, through
which the region's consortium
of six teaching hospitals pools
Graduate Medical Education
(GME) payments from area
medical insurers and redirects
these funds to train more residents in geriatric care. Funds
are also set aside to train residents in primary care and to
recruit and retain more minority residents - a strategy recently cited in Hospitals, as a
national model for promoting
primary care and reshaping
graduate medical education.
"We're using this as as tim ulus to move us institutionally
mal methodologies and patient demonto help in these missions, " says john P.
strations.
Changes in the curriculum reNaughton, M.D., vice president for clinical affairs and dean of the School of Medi- lated to the medical problems of an aging
cine and Biomedical Sciences. During the population will occur as the faculty develnext three years, the IME will provide ops interests and integrates them into the
between $4 million and $5 million for curriculum."
Already, Susan H. Schwartz, M.D., diresident training in geriatric and primary
care, disbursing funds through an internal rector of UB's third-year medicine clerk-

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ship and assistant head of medicine at
Buffalo General Hospital, has altered the
medicine rotation to include outpatient
exposure to the elderly this year for the
first time. "Compared to their
current exposure, this will
change medical students' attitudes tremendously," Schwartz
says. "The in-hospital exposure to the elderly is an unfortunate one. For students on inhospitalrotation, the elderly are
the people who are in the hospital to die. They [the patients]
are at their worst in an acute
setting, away from home, where
they're disoriented. It can be
very frustrating for students to
deal with. "
Next year, Schwartz says,
four of the 11 weeks of the
medicine rotation will beat outpatient sites such as nursing
homes and day care centers for
the elderly. "It's important for
medical students to see older
patients in outpatient settings
where they're walking, talking
older people who may have assorted medical problems but
are still functioning," she says.
"They will see being elderly does
not mean being completely infirm, and that there is a reward,
clearly, for dealing with the elderly. It's both an emotional
reward of just interacting with
older people, and it's also the reward that
you can make people better, that there are
curable or chronic illnesses you can modify
if not totally cure. ,
The geriatric initiatives funded through
the IME Demonstration Project also reflect the progress of physicians' understanding of the needs of the elderly -

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�approximating the ratio that will prevail in the country as a whole in another 15 years.

emphasizing preventive and chronic medical care, outpatient care for ambulatory
older patients and interdisciplinary geriatric teams.
Until recently, many physicians assumed that increased physical frailty was
inevitable as aging progresses. A more
current approach, often referred to as "successful aging," in reference to the landmark article in Science, "Human Aging,
Unusual and Successful" byjohn W. Rowe
and Robert L. Kahn, is gaining credence as
research indicates that a healthy lifestyle
and prevention of conditions such as heart
disease and osteoporosis that are often
present in an older population lead to
increased longevity and a higher quality
of life in later years.
john Feather, Ph.D., director of the
Western ew York Geriatric Education
Center, which serves as a regional
resource for geriatric education,
observes, "If you think of
aging as an inevitable
degenerative process, then what's the
point of trying to
help people? You
should just try to make them
as comfortable as possible. However, if
the frailties associated with old age are
really disease-specific, then you should
aggressively treat disease at any age. The
truth probably falls somewhere in the
middle; even if you solve every disease,
that person isn't going to live forever. "
june I. Chang, M.D. , who coordinates
the education and training programs in
UB's Division of Geriatrics/Gerontology,
concurs. "A middle ground might be
described as progressive aging, making
people as healthy as long as possible, but
accepting that some physical changes are
going to occur."
These philosophic approaches to medi-

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cal care of the elderly have real consequences, she says. For example, though
there is some senescence in aging, Chang
says, people shouldn't forget important
things like their child's name or someone
who is a close friend. She observes, 'Tve
had patients with memory loss say there's
nothing

sume that some surgical procedures or
aggressive treatments would not be appropriate; but in many of these instances,
treatment might extend life by another 10
to 15 years. Typically, students may not
be aware of the importance rehabilitative
therapy or assistive devices could have in
improving the quality of life for older
patients, she says. And they often
Number of c ertl·r·led Geriatricians
aren't aware of how changes re40,000 lated to aging affect which medications should be prescribed.
Even practicing physicians have
....---.~ 30,000 a tendency to misdiagnose the
symptoms of older patients, frequently failing to diagnose the treat_ ____, 20, 000 able medical problems that affect
the health of older persons, Chang
says.
Medicine's approach to older
patients will clearly receive more
and more attention in the decades to
come due to the sheer numbers of
patients living to their "golden years. "
T. Franklin Williams, M.D., the immediate past director of the ational Institute
that on Aging and a professor of medicine at
can be the University of Rochester, says, "Bedone, that's cause of the rapidly increasing numbers of
normal with ag- older people in our society and especially
ing. But this symptom really should be the very old, there's no question but that
looked into. It could be a problem with the predominant amount of medical pracmedication, depression, a stroke or tice in essentially every field will be with
Alzheimer's disease. Likewise, sleeping olderpatients-orthopedics,generalsurproblems that patients typically attribute gery, urology, family practice, internal
to age could be symptoms of congestive medicine and cardiology, and so on,
heart failure which gets worse at night, through every medical specialty.
depression, improper medication or uri"The team approach is the key direcnary problems."
tion for geriatrics, and specifically for the
Chang works closely with medical stu- most complicated patients," Williams
dents to address common misconceptions says. "That's true because the most comabout older patients. She says medical mon situation is a relatively older patient
students frequently have a mistaken im- who may have two or three different morpression that people in their 70s or 80s bid medical complications, and may have
don't have long life expectancies, and as- depression, dementia, plus social prob-

Jo,ooo

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�related to care of the elderly with practicfor Graduate Medical Education.
lems and functional losses as a result.
"These
two
settings
will
expose
resiing
physicians and medical educators in
"This is not only recognized in acavirtually
every specialty.
dents to the practices and principals of
demic circles, but many community hosChang concurs. "Our goal for geriatpitals recognize that they need geriatricall y geriatrics with an emphasis on continuity
specialized physicians, or geriatricians, on of care for elderly patients. These are real rics in general should not be training
experiences in alternative settings away geriatric physicians, but to accept a role
staff. They also recognize that in order to
be known in a community as the right from acute care facilities, " says David W. as teacher and distributor of information
place to come if you're a frail older person Bentley, M.D., head of UB's Division of to our colleagues. " Part of this mission,
Geriatrics/Gerontology and the project she adds, is to convince medical stuwith complicated problems, you've got to
director for the Geriatric IME Demonstra- dents that care for the elderly is chalbe well-staffed."
lenging.
An integral element in the develPopulation in Millions, 65
"Attitudes are changing,"
opment of needed geriatric experand older
10 she says, "but they're changing
tise at UB's affiliated teaching hospitals, the Indirect Medical Education
very slowly."
Demonstration Project this year proIn the absence of a single
60
vides $130,000 in funding from the
university-affiliated teaching
=
seven-hospital consortium for two
hospital - which elsewhere
t-_
- ____ ,
new interdisciplinary team initiatives
have been criticized as being
-~
overrun by medical specialists
to train UB residents in geriatric
~~£40 and isolated from their commucare:
nities- six of the teaching hos• Beginning in October, 1993, a
30 pitals affiliated with the UB medinew, mobile geriatric assessment
team will treat older persons who
cal school produced the bluelive in the community at ambu20 print for this first three-year
latory care sites at area hospitals.
phase of the IME DemonstraThe team, composed of a geri- 19--~:::-:--k:::
J0
tion Project.
atrician , nurse practitioner and
90 2000 ~ k::
Based on the project's ansocial worker experienced in the care of
201 0
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ticipated success, UB medical
older persons, will provide consultauons
'n::AI{
2030 ~
school was asked to make a
20 40 presentation to the U.S. Congressional
as requested by;residents and their intertion Project.
nist-preceptors. Resident training will be
ationwide, the demand for geriatric- Commission on Health Care Financing.
aughton and senior staff associate
provided through these consultations, as
trained physicians has already outpaced
ancy Gleico represented UB at the hearwell as through team conferences and supply. The Alliance for Aging Research
recently asserted that the U.S. , which now ings that explored ways to change the
seminars for approximately 40 residents
during the first year.
has 4,084 physicians certified in geriat- direction of graduate medical education
• A new Geriatric Evaluation and Manage- rics, falls far short of the 20,000 needed to for which the federal government spends
ment Unit, located at the VA Medical deliver medical care to the nation's 30 $5 billion a year.
"We're ahead of where the country
Center, will provide rehabilitative assessmillion persons over 65. This Washingment and care for frail elderly patients.
ton-basednon-profitorganizationprojects should be going," aughton says, adding
Theinterdisciplinarymembersofthis unit that by the year 2030, when there will be that for UB and other medical schools
will also provide consultations to the VA
more than 65 million Americans over 65, "One of the challenges for physicians wili
MedicalCenter'sacutehospitalunits,adult more than 36,000 geriatricians will be be to coordinate medical care with specialday health care program and the geriatric needed.
ists from the allied health professions.
However, it will not be possible to keep Another challenge will be to integrate care
ambulatory clinic. This program is expected to train approximately 20 Departpace with this projected demand. Instead, and prevention.
ment of Medicine residents next year in a Bentley, who is also director of UB's
"As the reemphasis on developing more
proposed, required geriatric module rec- Multidisciplinary Center on Aging, sug- generalists occurs, and we turn around
ommended by the Accreditation Council gests that geriatricians should share data our specialty model, it can be done. " +

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�lRf~li~G l H[ flDfRl~
arion Z. Goldstein, M.D., receives equate severity to require treatment, and
nearly two calls a week from nearly 63 percent of this group receive no
women who are concerned about treatment. Among persons over 65 living
the quality of medical care pro- in institutions, an estimated 65 percent of
vided to their elderly mothers.
older persons require mental health serOften, the calls come as a com- vices, yet 91 percent of them receive no
plaint, says Goldstein, director of the UB treatment.
medical school's division of geriatrics. "The
Team care is well suited to older paprimary care physician has just relegated
whatever symptom is presented as just 'old
age' or 'confusion."'
A board certified psychiatrist with added
qualification in geriatric psychiatry,
Goldstein describes the common scenario:
"The physician sent the elderly and their
families away, saying you're just getting
confused, getting old- without making
distinctions between what is treatable and
what is related to getting old. The stereotyping is horrendous. It's a matter of
perceiving treatable, potentially reversible
conditions as normal when they could be
treated."
She notes, for example, that if the symptom is memory loss, physicians need to
conduct a differential diagnosis of the nature of the memory loss to identify how
severe it is, whether it's something the
person needs to adapt to, whether it's
progressive or whether the anxiety and
depression associated with it are treatable.
A complicating factor: older patients
are also often reluctant to acknowledge
mental health problems, she adds. "They
often are unaware of treatable mental health
issues or attach a great deal of stigma to it.
There's a great deal of fear of the mental
health field by this elderly group. They're
afraid their independence will be taken
away."
Depression is by far the most common
complaint among an older population.
Other typical mental health problems
among older persons include dementia,
anxiety, paranoia and alcohol abuse.
In fact, research indicates that 7.8 percent of adults over 65living in the community have psychological disorders of ad-

1111111•

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tients, Goldstein observes. "We need to
address the specific needs of each individual much more adequately than we
have so far. Our whole society needs to do
something about the fragmentation of care.
Hopefully the next generation will find it
much more easy to seek out and find
services they need. "
+

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�ul G. Bulger, 68, was reading a report at work one day, rubbing his eyes, when
suddenly a giant black blotch covered the right side of the paper. When he looked
up, the dark spot remained in his right field of vision. Alarmed, the former president
of Buffalo State College had an assistant rush him to his ophthalmologist. There
he learned that the condition in his right eye, age-related macular degeneration,
would soon affect his left eye as well. Two years later, in 1988, while relaxing with
his family at a wilderness summer cottage near Albany, the prognosis came true.

�hough laser treatment in his left
eye preserved some peripheral
vision , Bulger was now legally
blind. His ophthalmologist told
him nothing more
could be done to restore his vision , and
sent him on his way.
Bulger, frightened by
his loss of vision , soon resigned
from his position as interim director of the Buffalo &amp; Erie
County Historical Society. He
became increasingly irritable, dependent on others, and subject
to depression.
Anticipating the needs of a
growing population of elderly
disabled persons like Bulger, a
group of clinical and research
faculty at the University at Buffalo recently founded a rehabilitation , research and infom1ation
center for me elderly known as
the Rehabilitative Engineering
Center on Assistive Technology
and Environmental Interventions for Older Persons with Disabilities.
The center is the first of 18
national rehabilitative engineering centers to focus exclusively
on ilie needs of the aging. It
officially opened in September
1991 wiili the initiation of a fiveyear, $2.5 million grant from the
Department of Education's ationa! Institute on Disability and
Rehabilitation Research. An additional $2.5 million in matching funds were provided by UB
and oilier sources for the center.
William C. Mann , Ph.D. , director of
the center known informally as the REC
on Aging, says, "We have a unique service
orientation. The ultimate goal of the
center is to improve me quality of life by

helping people maintain independence in
the face of the aging process. While the
physician is more typically involved with
disease and medical treatment, we are

addressing issues of long-term disability,
and providing solutions ilirough assistive
devices and environmental interventions."
Referred by his physician shortly after
the REC on Aging received funding in
1991 , Bulger visited the center for a full

diagnostic review. The age-related macular degeneration that he suffers from occurs among an estimated 17 percent of
Americans who are 60 years and older,
and 30 percent of those 75
and older. Specialists identified two devices that would
be of use to Bulger: a portable reading device and a
computer with voice playback software.
Though he remembers his
early days ofblindness as, "A
low spot that was pretty
rough on me, and on other
people around me, especially
mywife,"Bulgersays. "With
these devices, there is a tremendous elevation of the
psyche. I have relatively few
days of depression anymore."
The REC also helped
Bulger apply for financial
support for me new devices,
and provided six weeks of
instruction on the devices.
Bulger hopes to establish a
consulting business, and is
already using a desktop device that enlarges print for
reading and writing that the
Blind Association of Westem New York helped him
obtain in 1989.
Emmett Turner used the
center's services to obtain a
wheelchair specially molded
to his body. Turner was 58
years old when he fell down
a flight of steel stairs on ilie
ship he was working on and
broke his back.
The former construction firm owner
and port authority foreman couldn't sit for
long periods of time in his first wheelchair
and found it painful to ride over bumps.'
In ilie new wheelchair, Turner can sit

"

nstead ofpatients who need treatment, older persons should be viewed as consumers who

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�process, accidents, developmental disabilities or disease. Among the medical conditions typically associated with aging that
predispose to disability are arthritis,
Alzheimer's, osteoporosis, cancer, heart
disease, the inability to regain balance and
neurologic diseases such as Parkinson's.
Another REC client, john See!, a 71year-old information systems specialist who
became legally blind from macular degeneration in 1988 now uses a voice-activated,
specialized software package for a new
computer that the center helped him obtain and learn to use.
See! says if he had known of the center
when he was first diagnosed, "It would
have made all the difference in the world."
Using this equipment, See! works from
his home as a computerized maintenance,
inventory and purchasing specialist for
area corporations. He works for the income, and also because, "I would have just
dried up and blown away if I didn't have
something to keep me active."
One of the RECs goals is to bridge the
divide between geriatric specialists and
rehabilitative engineers. "The technology
people are not focusing on aging, and the
aging people are not focusing in on rehabilitative technology and the applications
of assistive technology and environmental
interventions," says Mann, a licensed occupational therapist. "Perhaps we can
bring them together."
The center's cross-disciplinary team
includes UB faculty in the School of Medicine and Biomedical Sciences, the School
of Engineering, the School of Architecture
and Planning, the Department of Communicative Disorders and Sciences, the School
of Health Related Professions' Department
of Occupational Therapy and specialists
from UB's teaching hospitals and numerous state and local service agencies.
In conjunction with their research efforts, these varied specialists provide wideranging, individualized client services that

for nearly l2 hours, and is comfortable
riding over uneven surfaces. "I go more
places, and stay longer," he says. "It makes
me feel a lot better."
The medical community is on the front
lines as the aging of America takes its
financial and emotional toll. Currently,
one in five Americans is older than age 55,
as compared to one in 10 in 1910. By the
year 2050, Census Bureau projections indicate this ratio will be one in three.
Physicians are accustomed to providing medical solutions to health problems.
However, as the nation's elderly population grows, the medical community is
becoming increasingly aware of the need
for non-medical approaches to improving
the quality of life for older patients, many
of whom face disability or loss of function
to one degree or another as they age.
While advancing age isn't always accompanied by disability, there is a strong
relationship between age and disability or
the need for assistance with the basic
activities of daily life.
A U.S. Census survey of non-institutionalized people conducted in the mid1980s found that 9.3 percent of persons 65
to 69 years old needed assistance with one
or more activities such as dressing, eating,
personal hygiene, housework, keeping
track of finances or getting around outside
the home. This rate rises steadily with age
to 10.9 percent of persons 70 to 75, 18.9
percent of persons 75 to 79, 23.6 percent
of persons 80 to 85 and 45.4 percent of
those 85 years and over.
These rates were significantly higher
among persons living in an institutional
setting.
The research and service activities of
the REC on Aging focus on restoring a
measure of independence to those older
persons whose limitations to mobility,
speech, vision, hearing, strength, coordination or mental acuity are caused by
normal changes associated with the aging

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�he ultimate goal of the center is to improve the quality of life by helping people

include in-depth assessments of each
client's functional abilities, limitations and
goals; identification of technologies that
meet clients' needs, and assistance coordinating third-party payments for purchasing and training on new devices.
The center also features a full-scale
interior design testing center where
changes in the layout of a home or office
are tested before expensive modifications
are made. lt also boasts computer and
device laboratories where clients choose
devices that will be most useful.
The research component of the REC
focuses primarily on persons 60 years and
older. Interviews with about 600 of the
center's clients will be used to identify
which assistive devices on the market are
most u eful for older persons, whether
new devices should be created to meet
their needs and how to make their living
and work space more functional.
Based on this input, the REC on Aging

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will design devices that are not currently
commercially available to disabled older
persons.
Items the REC has already invented
include a "smart" microwave oven that
reads cooking instructions off bar codes
and a motorized wheelchair testing platform to which a conventional wheelchair
is attached, providing a cost-effective
means to evaluate different models of
motorized wheelchairs.
The survey will also be used to identify
and meet the needs of the older disabled
person's family members and professional
care givers. Survey respondents will be
interviewed over regular intervals during
the the REC's five-year education department grant, enabling the center to evaluate the long-term effectiveness of its services and the usefulness ofspecific assistive
devices and modifications in living and
work space.
In keeping with a national trend to-

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ward patient empowerment, joseph P.
Lane, an associate director of the center,
observes that, "Instead of patients who
need treatment, older persons should be
viewed as consumers who need information to make rational choices. They have
a role to play in decision-making. "
Glen E. Gresham, M.D., chairman of
rehabilitative medicine at UB and medical
director at Erie County Medical Center,
shares this perspective. just as internists
consult with a surgeon if they think a
patient needs an operation, he recommends that physicians with older patients
with disabilities should consult with rehabilitative and geriatric specialists as well as
the REC on Aging.
"If physicians have patients who have
functional problems that are limiting their
lives, they shouldn't just say, 'You have to
live with it,"' says Gresham. "The focus
should be to help people stay functioning
and independent as long as possible." +

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�maintain independence in the face of the aging process.

to mobility, vision, speech and hearing to
read, write, control their environment and
communicate in person and over the
phone.
* Inspection of home and work settings,
full-scale testing of recommended modifications such as the enlargement of doorways or installation of hand rails.
* Assistance coordinating funding from
state agencies, insurance companies and
employers. (The REC on Aging's fee-based
services are covered by many insurance
plans.)
And for service providers and care givers for older persons with disabilities, the
center provides:
*Training and informational seminars for
rehabilitative engineers, occupational
therapists and institutional care givers for
the elderly.
* Presentations to residents of nursing
homes and self-help groups for the disabled.
* Presentations to advocacy groups for the
aging, hospitals and church groups aimed
at attracting clients who may regain independence with the center's assistance.
For more general information, contact
information coordinator Thomas Burford,
Ph.D., and forreferrals for services contact
Peggy Strassheim, social worker, at (716)
831-3141.
+

he University at Buffalo's new Rehabilitative Engineering Center on
Aging offers wide-ranging services.
For the medical community, the
REC on Aging provides:
* A center to which patients may
be referred for evaluation and assistance.
* Information about the effectiveness of
more than 20,000 assistive devices and
modifications to home and work settings.
*Training for rehabilitation medicine residents, participants in UB's geriatrics/gerontology fellowship program, nurses,
counselors, social workers, engineers, occupational and physical therapists and
speecManguage pathologists.
Because the REC on Aging shares the
facilities of the University at Buffalo's Center for Therapeutic Applications of Technology, the following services are available to disabled persons of all ages:
* Free information and referrals.
* In-depth evaluation of needs and abilities, including identification of helpful
devices and environmental modifications
and installation and training on new
assistive devices.
* Custom modification of wheelchairs.
* Computer facilities where clients may
sample hardware and software designed
to help people with significant limitations

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�•

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''
•

n the centennial a iversary of the
founding of th Sch l of Dental
Medicine and the 25 year since
graduated from it, Ros ell Park Cancer
Institutes William Carl, D.D.S., climbs
Ojos del Salado, the second-highest eleva. in the Western Hemisphere.
This is his story.

xl &amp;Photos By
illlam Carl D.D.S.

�•

�he world looks warm and
pleasant through the windows of the Restaurant
Miramare in Caldera,
Chile. In the harbor, pelicans dive for fish. Small
boats sway gently in the
water. Beyond the bay,
small houses, painted
white and green, with flat
roofs, cling like aphids to
the desert slopes. The sun warms my back
and face and drives the last of the lingering
cold out of my body.
Forty-eight hours ago, I stood on the
crater rim of Ojos del Salado and shivered
in the summit wind and fog. But now the
Atacama Desert and its high plains and
mountains are memories of an adventure
into a great and unique wilderness.
The Atacama Desert in northern Chile
is one of the driest deserts in the world. It
begins along the Pacific coast as gentle,
sandy slopes and terminates inland in
snow and ice-covered mountains of more
than 20,000 feet high. No rivers flow
through this desert; no rain wets the
parched earth. The merciless sun during
the day, the ever blowing wind and the
bitter cold of night, have reduced all life to
a minimum. What does grow in that
desert of sand plains, saline lagoons and
dry salt basins hugs the sterile earth firmly
as tufts of coarse yellow grass.

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��THE CLIMBERS ENJOYING A BATH IN THE LAGUNA VERDE HOT
SPRINGS AT 15.000 FEET .

he creatures that inhabit
this barren, desolate region reflect its colors in
their feathers or furs. The
few Oamingos on the
shores of the saline lagoons
don't have the bright pink
shades of their African
relatives. The furs of the
occasional guanacos blend
in with the maize of the
salt flat grass, and the small lizards here
and there scurry like fleeting shadows
over the gray and brown sand. But then
there are the rare humans wearing bright
blue and red Goretex clothing in this
endless wilderness: miners and adventurers searching to fulfill their ambitions and
explore where few have tread before.
What brought me to this end of the
world? Once a year I feel the urge to get
away from it all, leave civilization behind
and test myself against the adversities of
nature. I had climbed Kilimanjaro,
Aconcagua, Cotopaxi and Chimborazo.
But all of these mountains had the marks
of tourism on them. Probably half a
million people had climbed Kilimanjaro
by the time I did.
On Aconcagua - the highest mountain in the Western Hemisphere - the
base camps were cramped with climbers
from around the world and littered with
garbage. Cotopaxi and Chimborazo were
covered with snow and ice. That made
them a little le s attractive to the average
amateur climber.
This time I was looking for something
different. When I contacted Greg Wilson,

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my guide from Aconcagua, he immediatelysent mea list ofout-of-the-wayplaces.
I picked Ojos because at 22,000 feet, it is
the second-highest mountain in the Westem Hemisphere. Fewer than 150 people
have climbed it. Climbers like those credentials.
Besides, in 1992, the School of Dental
Medicine in Buffalo celebrates its 100th
birthday. I promised Dean Feagans to take
the banner of the school to the top.
There were four of us, all veterans of
many mountains, waiting anxiously in
Miami in March for the flight to Santiago,
Chile: Peter Spatt, an internist from Colorado; Thomas Sieben, a pharmacist from
Connecticut; David Hersey, a psychiatrist
from Michigan, and me, a dentist from
Buffalo.
We had a specialist for any potential
physical and emotional problems. In addition, there was Greg Wilson, our guide
from Idaho who had recently climbed Mt.
Everest and met Fernando and Missal, our
Chilean drivers and part-time guides.
From Copiap6, we headed north-east
into the plains and canyons of the Atacama
desert with two, four-wheel drive vehicles,
leaving civilization behind. Life on land
seemed to die. Clouds of dust and endless
sand flats and dunes surrounded us. On
the eastern horizon, rugged mountains
met the blue sky in sharp silhouettes.
The sun was only a few inches above
the far horizon as we reached the first
saline lagoon. The few flamingos munching in the shallow water took off as soon as
we approached the shore. By now we were
12,000 feet high and the cold crept in

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closer as the sun dipped.
That first night was a restless one; I
never sleep well at high altitudes.
The heat already made the air shimmer
over the salt flat as I opened the tent flap
the next morning. In the east, the three
crosses - snow-capped mountains of
about 21,000 feet altitude - suddenly
loomed on the horizon. The Argentinean
border was not far away.
We camped for three days at 14,000
feet altitude to acclimatize to the altitude
and then moved up to 17,000 feet. The
best insurance against altitude sickness
and pulmonary edema is gradual adaptation. Because the mountain air is cold and
dry, hydration is crucial. Our high camp
was at 19,000 feet, immediately at the foot
of Ojos del Salado. Everything around
oozed barrenness and isolation. On one
side was the mighty massif of Ojos; on the
other and below stretched the magnificent
Atacama Desert with its canyons, driedout riverbeds and endless chains of snow-

,

W ILLI AM
C ARL . D .D .S ..
DESCE N D ING
F ROM HIGH
CAMP A T
19 .000 FEET .

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�capped mountains.
We had been at high altitude for more
than a week and I was anxious to get to the
top after a few hours of rest at high camp.
But Greg decided to allow for another rest
day before our ascent. Finally, March 21st
arrived - the first day of autumn in the
Southern Hemisphere and the day we
made our first attempt for the summit.
We had packed ropes, crampons, provisions, water bottles and extra clothes the
evening before. The anticipation was palpable. At 4 a.m., there was something
different about Ojos. The top had an
ominous white cap with a tail pointing
toward the east. The cloud lingered at first
on the summit ridge and then enlarged.
Still, in the silvery moonlight, we continued in countless switchbacks up the scree
slope until we reached the lower edge of
the glacier at 20,000 feet.
With the rising sun came the first gusts
of wind carrying crystals of ice and snow.
Above, the mountain top melted into

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dense, fast-drifting clouds. Reluctantly,
we turned back to the refugio hut. Cold
and miserable, we sat around and cursed
the weather. "You pay for the summit in
the currency of toil," Greg philosophized.
But in this weather, you couldn't even see
the summit, let alone toil for it.
All day the wind rattled the hut and
snow showers alternated with moments

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of brilliant sunshine. When night came,
no silvery moonlight illuminated the slopes
of Ojos; its head remained in the clouds
and our dreams of the summit began to
evaporate. But weather in the mountains
is unpredictable. I fell asleep in the small
hours of the night and dreamed I flew a
small airplane from mountain range to
mountain range. It was 4 a.m. again when
Greg called, "The top is clear, the wind has
died." We rolled out of our sleeping bags
and in the narrow space between the bunks
fum bled around for our climbing gear. At
this altitude, any exertion, like putting on
boots and gaiters, is torture.
At 5 a.m. we started to retrace our steps
up the mountain. By the time the sun was
well up we had reached the level of the
glacier where we had to cross it. We
strapped on crampons and roped up. The
surface broke in large slabs, the snow
underneath the ice sheet was soft and
deep, up to the knees. Lifting your legs for
each step out of a hole just to advance
another 10 or l2 inches is agony at this
altitude. Soon I measured my progress in
half-boot lengths. "Breathe harder," I
heard someone yell from above. I tried to
answer, but no sound came out of my
mouth, only a cloud of vapor that warmed
my face momentarily. I concentrated on
pressure breathing; breathe in deeply and
let the air out with an explosive burst. The
slope ahead looked steeper than anything
I had ever climbed before. I conjured up
the image of the little airplane that took me
so effortlessly to the mountain tops in my
dream and struggled on. The pain in my
legs and the continuous gasping for air
eventually gave way to my renewed deter-

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�summit of Ojos del Salado. To climb it,
some technical know-how with ropes,
jumars and descenders was required. I
did not have that skill; besides, being
scared of heights, I did not want to dangle
from a rope at that altitude. Twenty-two
thousand feet is respectable.
The descent was long and slow, almost
as tiring as the ascent. We met the sun
again at the upper edge of the snow field
and I had a picture taken with the centennial banner of the School of Dental Medicine. We had climbed and descended
from 5 a.m. to 5 p.m.- a full day's work.
I squeezed a few drops of water out of my
frozen bottle and then dropped into my
sleeping bag. I left summit jubilation for
thenextdayand the long trek back through
the desert.
Climbing a mountain like Ojos is more
than just physical toil - you have to be
prepared for conditions that are not on an
ordinary day's schedule. One thing is
cleanliness. If you are obsessed with it,
forget an adventure like this. I didn't wash
my hands, let alone the rest of me, for two
weeks. There is sand everywhere - in
your clothes, in your sleeping bag and
between your teeth. The toilet is the far
side of a designated big boulder. It offers
privacy, plenty of sand and lots of ventilation. You have to bring your own toilet
paper and shovel.
ights can be difficult on high mountains. You wake up out of a half sleep and
your tongue sticks to the roof of your

mination. Mini-breaks, while I waited for
the slack of the rope ahead of me to pick
up, sometimes allowed me to catch two or
three breaths before the next step. That
was sheer luxury.
he steady deep breathing,
the exertion and the dry
air of the high mountains
made my tongue and
throat raw and painful. A
short break, only a short
break to get a drink of
water, kept racing through
my head.
We reached the end of
the snow field by early afternoon. Willpower and physical strength
shriveled down to two and three breaths
for each step of progress for the last few
hundred vertical feet to the crater. We
struggled up the ridge toward this almost
imaginary point, so close to the eye, yet so
far for the tired and aching muscles and
oxygen-starved lungs. And then suddenly
the ground leveled and we were there, on
top of our world.
I knew from other summits that there
would be no magic insight into man and
nature, no voice from heaven at that moment. My only thought was: I have to
climb no more.
The sun was by now behind the clouds
and fog rolled in. From the rim, the
depression of the crater stretched beyond
the rocky elevation that was the actual

mouth. You fumble around for your
water bottle that's not frozen and squeeze
out a few drops. And then you have to visit
the far side of the boulder. At first you
think about not getting up and going out
into the cold for a while, but then nature
demands action. You crawl back into
your sleeping bag and a little while later it
starts all over again. Some nights I had to
get up five or six times. That's the price of
hydration on high mountains.
Physical fitness is essential for climbing. For a couple of months before I left
for Chile, I toted heavy loads up and down
Omphelius and Pfamer Roads in the Boston Hills, collecting curious looks from
people in passing cars. But Ojos del Salado
is different from the Boston Hills. As you
struggle higher and higher, your back-

THE UNIVERSITY OF ATACAMA·s .. REFUGio·· HUT AT 17.000 FEET .

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�The memories of the
cold, the wind, the sand
and the toil faded as
the snow-covered peak
of Oj os vanished on the
horizon.
But the
memory and the glory
of having made it to
the top always linger
for a long time. And
since this was our centennial year at the
School ofDental Medicine in Buffalo and a quarter of a century
since I graduated from that school, the
summit of Ojos was a particularly memorable experience for me.
But this was really more than just a
mountain climb. It was an adventure into

pack feels as if it weighs a ton and the
straps cut mercilessly into your shoulders.
Every muscle aches; your lungs never
seem to get enough oxygen. You want to
get to the top, butgravitywants you down.
It becomes a balancing act. And then you
begin to wonder what you are doing here.
If you have any quit in you, the mountain will find it.
When you set one foot in front of the
other for hours and hours, you need something to occupy your mind. I wrote a few
acid letters to people I didn't like. I counted
from one to 100 in three languages, then
did the multiplication tables and recited
poems I had learned in school many years
ago. I always knew they would come in
handy some time.
We left the mountain in high spirits.

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the unknown. Even Greg had not been to
this part of the Andes before. For a directional guide he used an article someone
had written a few years ago for a magazine.
That's the kind of stuff great adventures
+
are made of.

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'

Proied aims to ease shortage
of primary care physicians
MODEL PROGRAM ESTABLISHED AROUND CONSORTIUM

$5 million demonstration project that could
become a model for easing the nations current
and projected shortage of primary care physicians is being initiated by the School of Medicine and
Biomedical Sciences, six of its affiliated teaching
hospitals, theNew York State Department of Health,
Jour private health insurance payers and Medicaid.
The unique project is organized around UBs Graduate Medical Dental Education Consortium ofBuffalo
(GMDECB).
"The Reimbursement Demonstration
Project represents a major cooperative
effort on the part of our teaching institutions and graduate medical education directors to respond to known problems
that face medical education, the medical
profession and health care," said john
aughton, M.D., vice president for clinical affairs and dean of the medical school.
aughton, who chairs the GMDECB,
will direct the three-year project, which
also could pave the way for the more
efficient use of graduate medical education dollars paid to hospitals. The project
will also address ew York State's press-

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ing need for more physicians to care for its
growing elderly population as well as
increase its pool of minority physicians.
"We will strive to increase our commitment to the educational preparation of
more generalists, and to attract increased
numbers of underrepresented graduates
from minority and socio-economically disadvantaged populations," augh ton said.
"This effort shows the importance of
cooperation by a number of diverse constituencies, each of which is involved in
graduate medical education in some way,"
he noted. "Each has a responsibility to
provide the innovative leadership this

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project represents," he added.
William R. Greiner, UB president, said,
"The project is a clear and exciting example of the way in which we at UB and we
in Western ew York can lead in a time
when extraordinary new steps and unprecedented collaborations are called for.
"It's a network of partnerships within
our academic community; it's a way to
address critical needs here at home, as well
as a model for efforts throughout ew
York State and across the nation. It will
serve as a template for all of us here at UB,
too, as we focus our attention on developing such experiments and leadership
throughout our university's endeavors,"
Greiner noted.
Eight new health care initiatives - to
begin this fall - form the centerpiece of
the project, for which $1.13 million is
budgeted for start-up. Funding for the
remaining two years is set at $1.7 million
and 2.27 million. The funding is provided by the six hospitals through reimbursement from the insurance payers. The
hospitals, which currently are reimbursed
directly for their indirect medical education costs, will receive increased reimbursement rates and contribute a portion
of these reimbursements into a pool to
support the eight initiatives.
A primary goal of the demonstration
project is to increase the number of residents enrolled in the primary care specialties to 50 percent of the GMDECB's total
by 1994. Currently, 35 percent of the
Consortium's residents are enrolled in family practice, pediatrics or internal medicine.
A Primary Care Resource Center, to be
located in Beck Hall on the South Campus,
will house five health care initiatives aimed
at making primary care medicine - historically not as attractive professionally or
economically- more appealing to medical students.
ationally, less than 20
percent of medical school graduates enter
primary care - down from 50 percent in

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�without walls"- is fairly atypical of most
of the nation's medical schools, which
generally run their own medical centers.
The Graduate
Medical Dental
ten have longer
....~~~~~~~~~~~~~~. .r1~~~~"~~~~~~~~
Education Conand less predictsortium of Bufable hours.
falo came into
The Reimformal existbursement
ence in 1983
Demonstration
when the mediProject's prical school and its
mary care initiateaching hospitives would seek
tals entered into
to increase the
its first consorGMDECB'scadre
tium. Consisting
of primary care
of all affiliated
residents by:
teaching hospi4 Recruiting
tals, the Schools
medical students
of Medicine and
into primary care
Biomedical Sciresidencies
ence and Den4 Developing
tal Medicine, all
community sites
residency trainwhere medical
ing program diresidents can
rectors and one
practice
resident from
4 Developing a
each program,
medical school
the Consortium
curriculum track
governs all resiaimed at training
dency training
primary care leadprograms
ers
through a se4 Designing a
ries of comprogram to immittees.
prove the teachThe unique
ing of primary
program has
care faculty, and,
~
emphasized
0
4 Developing re~
cooperation
search opportuni~ rather than
ties and fund recompetition
search fellowamong
its
ships in primary
teaching hospicare.
tals , many of
Other aims of the
which were once consentation in its residency programs is 9
demonstration project insidered competing institutions.
+
clude incorporating geriatrics and the care percent.
UB's medical school teaching hospital
of patients with chronic conditions into
- BY NANETTE TRAMONT KOLLIG
model
itself- labeled a "medical center
residency training as well as reaching and

1963. Primary care physicians currently
earn about one-third to one-half the salary
their specialist colleagues do. And primary care physicians of-

maintaining an 11 percent minority representation in residency programs. UB's
current minority repre-

�•

..................... . ......... . ................... . ... . .... . ...... . ... . .. . .............. . ... . ..

.

I

Ador'' patients to be
used to test competency
of medical students
11

B medical students
\
soon will be ,
\
I
\
I
I
seeing pa~,
\
I
\
f
tients
' ' '•
''
w h 0
...
won't
besickatall. The
patients will be
faking - to test
how compassionate, caring and competent medical students are.
UB is joining Albany
Medical College, the
State University of
ew York Health Sciences Center at Syracuse and the nursing
program at Regents
College in a pilot program to uses tandardized
patients - healthy people
trained to portray the symptoms and characteristics of real patients - to test medical students' skills.
The project is funded by a two-year,
$200,000 grant from thejosiah Macy,jr.
Foundation. To carry it out, the schools
have formed the Upstate ew York Clinical Competency Center, one of six such
groups funded by the foundation nationwide, for a total of $1.5 million.
Using standardized patients allows examiners to compare and rate performances of students as they diagnose and
treat the same patients. Students know
when they are being tested with standardized patients, but the encounters take place
under true-to-life conditions.
"Many of us in medical education have
become increasingly concerned about the
use of standardized pencil and paper tests
I

.. .. .

as the primary, and at times, only measure
of physician competence," said Dennis
adler, M.D, associate dean and head of
medical education at the UB medical
school.
"This grant will allow us to start developing tools to assess a much broader
spectrum of attributes and skills a physician

..

should
have.
Knowledge,
critical
thinking,
f
\
I
\
sensitivity, social
skills and the
ability to communicate are just some of
the many components of competence we
hope to address in this new interactive
manner."
The program will begin in January
1993. By the end of the two-year grant
period, all fourth-year students in the three
medical schools will be required to pass
this new performance-based examination
by working with eight standardized patients.
Albany Medical College will set up the
patient training program during the first
year of the grant. The program will ex-

--

pand to the other campuses during the
second year. The ational Board of
Medical Examiners is expected to add a
clinical skills exam to its licensing process in 1995.
+
BY

LOIS

BAKER

Knight named chair of
Anesthesiology
Department
au! R. Knight, M.D.,
professor in
Department of
Anesthesiology at the
University of Michigan Medical Center,
.. has been named chair and
•• - - - professor of the medical
, \ ' ' .. school's Department of Anesthesiology.
A University of Michigan faculty member since 1977,
Knight also served as assistant and associate professor in the department of anesthesiology and an assistant research scientist in the department of epidemiology
there.
Before going to the University ofMichigan, he completed a residency in the departments of anesthesiology and surgery
at the Milton S. Hershey Medical Center
in Pennsylvania. Knight did graduate
fellowship training in
the department of microbiology at the
Pennsylvania State
College of Medicine.
Knight has authored
numerous journal articles and has delivered
many presentations. He
is a reviewer for thejournal Anesthesiology.
+
-

BY

MARK

POLLIO

�· · ·· ·· ·· · ······ ·· ··· · ······· ·· ·· · ·· · ·· ·· ····· · ··· · ····· ·· ······· · ········· ·· · ·· ··· ·· ··· ·· ·· ·· ··· •

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UB app6es for
maior Robert
Wood Johnson
Foundation grant
he University at Buffalo School ofMedicine and Biomedical Sciences has applied for one of 18
Robert Wood johnson Foundation planning
grants aimed at increasing
the number of medical
school graduates entering
generalist physician residency programs and practicing generalist physicians.
Under project director
john aughton, M.D., vice
president for clinical affairs
and dean of the medical school, UB's proposal uses its unique Consortium teaching hospital structure to improve the quality and numbers of primary care physicians it produces by effecting long-term
changes in recruitment, training and support of the generalist physician.
The planning grant is for one and onehalf years.
+

ers to receive the award in 1992.
Robert Adams of the IH's Cancer
Training Branch said career development

UB researcher studying
diet and cancer Bnk
wins NIH award
o L Freudenheim, Ph.D., assistant
professor of social and preventive
medicine, has received a $325 ,000
Research Career Development
Award from the National Institutes
of Health to support her research
during the next five years.
Freudenheim is one of eight research-

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grants are awarded to promising young
investigators who have established themselves in their fields.
Freudenheim has published articles
in professional journals on her research
into diet and osteoporosis and diet and
cancer.
Her work over the duration of the
grant will involve further investigations
into the effects of diet on breast and
endometrial cancers, as well as a study
of diet in Italy and its relation to cardiovascular disease and cancer.
A University at Buffalo faculty member since 1988, she received a bachelor's
degree in human nutrition from the
University of Michigan, master's degrees in nutritional sciences and epidemiology from the University of Wisconsin at Madison and a doctorate in
nutritional sciences from the University of Wisconsin .
+
B

Jo L Freudenheim, Ph.D

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�Harold Brody steps down as
chair of anatomical sciences

When the war was over, Brody was
assigned to a VA-type hospital on Staten
Island, where he worked in the OR until
he was discharged. From there, he returned to his hometown of Cleveland and
entered Western Reserve University "while it was still pure," Brody jokes about
WILL REMAIN ACTIVE IN MEDICAL SCHOOL TEACHING
what is now Case Western Reserve University- to study biology.
"While I was there," he says, "with my
ot only is UB's Harold Brody tor, but Haynes told me that unless I knew
probably the only chair of any the anatomy, I wouldn't be a help to him experience with the medical unit and all
the studying - I had kind of fallen in love
department of anatomical sci- ... and told me to leave the room.
ences who was kicked out of an
"From then on," Brody said, "I memo- with anatomy. I wanted to do something
operating room for not knowing rized Gray's Anatomy at night until1 a.m. with it, so I finally decided to go fora Ph.D.
anatomy, but he readily re- I would know what the [surgical] cases in anatomy," which he received from the
counts the incident and fondly recalls it.
would be the next day so I studied the University of Minnesota in 1953.
In 1950, Brody went to the University
In fact, he says, it is the catalyst that anatomy the night before." Haynes was
began his passion for anatomy and led to pleased. "He had kind of expected it," of North Dakota to head the teaching
program in neuroanatomy for 40 firsthis still-ongoing distinguished career as a Brody recalls.
"Gradually, I became more and more year medical students.
teacher and researcher in the field .
While there, his reputation as a reknowledgeable. And I never got kicked
Here is what happened.
searcher
and instructor spread, and with
Itwas 1944and Brody was in the Army out of an OR again. "
Brody eventually became so knowl- only one neurosurgeon in the state at that
medical corps. His outfit was stationed in
Southern England at one of a cluster of five edgeableand proficient that Haynes would time (and no neurologists) , he served as a
general hospitals set up there in anticipa- assist him. "I did a couple of craniotomies source for general practitioners on infortion of the French invasion. Brody and for shrapnel in the brainandaboutadozen mation on the nervous system.
"There was so much to learn," hereseven others had been working as surgical nerve repairs," he remembers.
members,
adding that he had a couple job
technicians and were trained to assist in
offersone
from Buffalo after a "hallway
and perform the closure of wounds, apinterview
by
Dr. 0 . P. jones" at a conferplying casts, passing instruments, etc. "At
ence in Galveston.
least from a mechanical point of view,"
"And so we came here," he says.
Brody says, "the enlisted men could close
That was in 1954, and Brody and his
wounds as well as the surgeons."
wife, Anne, had a one-year-old son, David,
It was about the time the Allies broke
now an attorney in Buffalo. Their second
through in ormandy and the surgical
son, Evan, who just completed his Ph.D.
suites of the general hospital were busy,
in exercise physiology, was born in 1957
handling as many as 50 cases a day.
while Brody was in his first year as a
"We were joined by a neurosurgeon
medical student. A year earlier, Stockton
from the University of Illinois - Walter
Kimball, the dean of the medical school at
Haynes. He was put in charge of developthe time, had asked Brody to consider
ing a neurosurgical unit. "
obtaining a medical degree.
Haynes chose Brody as his assistant.
Brody managed to complete his degree
"The first time I scrubbed with him was
five
years- all the while teaching gross
in
for a sciatic nerve repair. He asked me if I
anatomy and neuroanatomy and doing
could describe the anatomy of the sciatic
research. "I would teach when I had to
nerve," Brody recalls.
teach and attend class when I could."
''I'd never been expected to do anyChairman of UB's department of anathing but tie a knot fast and hold a retrac-

"With my

experience with the

medical unit and all
the studying- I

kind of fell in love
with anatomy. I
wanted to do

something with it."

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tomical sciences since 1971, Brody was marked by his ability to take it in new
one of the first people john aughton, directions in response to the burgeoning
M.D., vice president for clinical affairs and knowledge and changing aspects the field
dean of the medical school, met when he has taken. "Anatomy was almost exclusively teaching, rather than research,"
visited Buffalo in 1974.
"He was very warm, gracious and sen- Naughton recalls. "Brody recruited a fine
sitive," Naughton says, adding that Brody's faculty- good researchers as well as fine
tenure as chairman of the department was teachers. He has been a stalwart supporter

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of the University and the medical school
as he continued his own scholarly interests.
"He is well regarded as a teacher and
committed to the needs of his students.
His sense of humor and warmth have
served him well. His students feel very
good about the education they get in

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· ··· ···· · ··················· ··· ········ ·· · ····· · ·· ·· · ·· ···· ···· ··· · ····· ·· ··· ·· · · ·· ·· · ···· ·· · ···

.

'

n anatomy, you have a

"

very different and unique
relationship with your
students. You don't see
them just in lecture. The
faculty struggles through
with them. You come to
know your students
much better over a
dissecting table."
determine whether there is an optimum
number of cells necessary for activity to
take place."
With widely published journal articles
and book chapters, Brody, former editorin-chief of the journal of Gerontology, is an
editor of eurobiology of Aging and an
editorial board member of five other journals. President of the Gerontological Society of America and a founding member
of the ational Advisory Council of the
ational Institute on Aging, he continues
to be active in professional and community organizations, as well as on several
medical school committees. He is also
spearheading the development of an
anatomy museum "where everything will
be on display for the students to use. "
Brody, who was aided by Dr. Chester
Glomski, professor and vice chairman of
anatomy during his tenure, sees more
changes ahead- not the least of which is,
he hopes, another name change that better

anatomy, and," aughton adds, "it is not
an easy set of courses to teach."
Indeed, Brody's--relationship with his
students has, in many ways, been shaped
by the very nature of the anatomical sciences courses.
"In anatomy," Brody says, "you have a
verydifferentand unique relationship with
your students. You don't see them just in
lecture. The faculty struggles through
with them. You come to know your
students much better over a dissecting
table and at the microscope."
Brody's major research interest has been
in studies of normal aging in the human
central nervous system. He is presently
working on the effects of aging and alcohol on the cerebellum, a study in which
Dr. Roberta Pentney, interim chairman of
anatomy, is the principal investigator. "I
have always been interested in cell numbers," he says.
"Ultimately, my interest is in trying to
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reflects the scope of the activity the department engages in. "One of the first things
I encouraged the department to do when
I became chair was to change its name. We
were responsible for teaching and research
in several subjects; I got tired of people
saying, 'Oh, you only have one course.'
We had not only gross anatomy, but neuroanatomy, histology and embryology.
"We've been the anatomical sciences
since then."
Brody has worked to change the
department's name to "anatomy and cell
biology" to reflect the additional focus of
neurobiology, cell biology, reproductive
biology, hematology and functional morphology. The change, suggested by Dr.
Barry Eckert, associate professor of
anatomy, and approved by the medical
school, is stalled at higher levels, but Brody
is hopeful it will move forward soon. +
-BY

NANETTE

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KOLLIG

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�....... . ... . ........... . ....... . ............. . ... . ....................... . .. . . . . . .... . ....... . .

1973 graduate appointed
U of Connecticut Health
Center interim chief
eslie Cutler, who received his Ph.D.
in pathology from the School of
Medicine and Biomedical Sciences
in 1973, has been named interim
vice president and provost for health
affairs and executive director of the
Farmington facility , including john
Dempsey Hospital, for the University of
Connecticut Health Center.
Cutler joined the
University of Connecticut School of
Dental Medicine's
department of oral
biology in 1973 and
has been associate
vice president and
associate provost for
health affairs since 1991. He previously
served as associate vice president for administration and research.
He is currently a professor of pathology
in the School of Medicine and a professor
of oral diagnosis in the School of Dental
Medicine. Cutler is also on the attending
+
staff of john Dempsey Hospital.

Cosgriff elected vice
president of New York
State medical society

state delegate to the
American Medical
Association. He is a
past president of the
Medical Society of
the County of Erie.
An attending surgeon and chief of
trauma services at
Sisters of Charity Hospital, he has been
active in numerous medical organizations
locally and at the state and national levels.
He is a fellow of the American College of
Surgeons, a fellow of the American Association for the Surgery of Trauma, a member of the American College of Emergency
Physicians, a founding member of the
ew York State Society of Surgeons and a
member of the Buffalo Surgical Society of
which he is a past president.
Cosgriff serves on the state medical
society's professional medical liability insurance and defense board. He is also a
member of the American Medical Association.
A diplomate of the ational Board of
Medical Examiners and the American Board
of Surgery, Cosgriff was recently honored at
a benefit dinner for Mercy Flight. He was
recognized for his contributions and dedicated service toward the improvement of
trauma care services in Western ew York.
Cosgriff has served on the board of directors
of Mercy Flight and is a past director of the
American College of Surgeon's Advanced
Trauma Life Support courses for ew York
State.
+

New officers elected to
M111ard Fillmore Hospitals

ames H. Cosgriff, Jr., M.D., a UB
clinical assistant professor of surgery, has been elected vice president of the Medical Society of the
State of ew York. The election
took place at the society's 186th
annual meeting held in ew York City.
Cosgriff had been serving as the state
medical society's treasurer. He also served
as assistant treasurer and is currently a

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ndrasj. Vari, M.D. , was recently
elected as president of the medical staff for Millard Fillmore
Hospitals. Vari, a clinical assistant professor of medicine, will
serve a two-year term.

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Other newly elected officers include
Thomas S. Cumbo, M.D., clinical assistant
professor of medicine, president-elect;
Thomas A. Lombardo, M.D., clinical instructor oforthopaedics, secretary; Sanford
R. Hoffman, M.D., clinical assistant professor of otolaryngology, treasurer, and
Robert M. Barone, M.D., clinical assistant
professor ofsurgery, immediate past president. Each will serve a two-year term. +

Taheri develops FDAapproved device to treat
hardening of the arteries
he Food and Drug Administration
recently approved a new device to
assist in the treatment of femoral
artery occlusion.
Called the Taheri valvulotome,
the device was developed by Syde
A. Taheri, M.D., clinical assistant professors of surgery at the University at Buffalo
and a thoracic and vascular surgeon at
Millard Fillmore Hospitals.
One of the common treatments for
symptomatic femoral artery occlusion is
vein bypass surgery. The Taheri
valvulotome allows surgeons to remove
the valves inside the vein used to bypass
the patient's femoral artery.
The device also permits simultaneous
measurement of the blood pressure
through the bypassing vein, Taheri explained.
"In addition to removing valves and
measuring blood pressure, the Taheri
valvulotome also allows for detection of
any abnormal communication between
the artery and vein, and can effectively
locate valves inside the vein," said Taheri,
who spent two years developing the instrument. He has performed more than 25
procedures using the new technique, all at
Millard Fillmore Hospital.
+

�•[21

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.

UB researcher to head
awision of prosthetic
materials at Sisters
nne E. Meyer, Ph.D., has be n
named head of the division of
prosthetic materials of the Head
and Neck Center in the department ofotolaryngology/head and
neck surgery at Sisters Hospital.
Recently appointed research assistant
professor in the School of Medicine and
Biomedical Sciences, Meyer is renowned
for her research in surface science. She
received her undergraduate degree from
the State University of New York at
Potsdam and earned her Ph.D. in surface
science, prosthetics, at Lund University,
Sweden. She formerly served as section
head of the surface science section at
Calspan Advanced Technology Center.
Meyer is also principal research scientist for UB's Industry/University Cooperative Research Center for Biosurfaces, as
well as a graduate faculty member in the
School of Dental Medicine's oral sciences
program and a research assistant professor in the department of biophysical sci+
ences in the medical school.

ology, will serve a two-year term as vice
president. Pieroni is a professor of pediatrics at UB and has been with Children's
since 1976.
Ehsan Afshani, M.D. , director of education for radiology and a clinical associate professor of radiology and pediatrics,
will serve a one-year term as secretary/
+
treasurer.

Sisters Hospital names
chainnan of obstetricsI
gynecology department

Alumni named department
heads at St. Joseph
ruce]. Cusenz, M.D., has been
appointed director of the plastic
and reconstructive section of the
department of surgery at St. joseph Hospital in Cheektowaga.
A 1981 graduate of the School
of Medicine and Biomedical Sciences,
Cusenz is an adjunct assistant professor of
surgery and dermatology at the University. Heisamember
of the American Society of Plastic and
Reconstructive Surgeons of Upstate
ew York and the
Buffalo Plastic Surgery Society.
Gerald
V.
Schwartz, M.D. , has been named chairman of the department of radiology at the
hospital.
Schwartz, a 1961 graduate of the School
of Medicine and Biomedical Sciences, has
been a staff radiologist at St. joseph since
1968. Board certified by the American
College of Radiology, he is a member of
the Buffalo Radiologic Society.
+

ichael Ray, M.D., has been
appointed chairman of the
department of obstetrics/gynecology at Sisters Hospital.
Ray had been acting chairman
of the department since 1991
and vice chairman since 1986. He is director of the hospital's antepartum fetal testing laboratory.
A clinical associate professor in gynecology and obstetrics, Ray is a graduate of
Georgetown University and earned his
medical degree from the School of Medicine and Biomedical Sciences at UB in
1965. He completed a fellowship in
perinatal medicine at the University of
Southern California and has done extensive post-graduate work specializing in
obstetrical ultrasound and antepartum fetal testing.
ormal]. Sfeir, M.D. , clinical asRay is a diplomat of the American Board of
sistant professor of medicine, has
ames E. Allen, M.D., a professor of Obstetrics and Gynecology, a member of the
been installed as president of the
surgery at UB's School of Medicine American College ofObstetricians and Gynemedical staff at Sisters Hospital.
and Biomedical Sciences, has been cologists, the Erie County and ew York State
Also installed were Paul Burstein,
elected president of the medical staff medical societies, the Buffalo Gynecological
M.D., clinical assistant professor
and
Obstetrical
Society,
the
American
Instiof The Children's Hospital of Buftute
ofUltrasound
in
Medicine
and
the
Ameriof gynecology and obstetrics, presidentfalo. Allen, acting head of Children's
Hospital's Department of Pediatric Sur- can College of Physician Executives. ln addi- elect; Daniel Castellani, M.D., clinical ingery and an attending surgeon there for 27 tion, he is a site visitor for the ew York State structor in neurology, secretary, and EdDepartrnentofHealth/ACOG District II Com- ward Bartels, M.D., clinical instructor in
years, will serve a two-year term.
Daniel R. Pieroni, M.D., chief of cardi- mittee to Reduce Cesarean Section Rate. + gynecology and obstetrics, treasurer. +

Medical staH officers
elected at Children's
Hospital of Buffalo

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�.. ... . . . ......... ............ . .. .... . .. ..... ........ .. ... ..... ........ ..... ................. . .

[I]

CLASS OF 1 953

"Can't believe it's 40 years!
See you in May."
M ICH A EL A . S ULLIVAN,
M .D., CHAIRPERSON

CLASS OF 1943

MARCH
"Don't miss our 50th Year
Reunion. Lookingforward
to seeing you."
D UNCAN K . M ACLEOD ,
M . D ., co-CHAIRPERSON

CLASS OF 1 943
D E CEMBER

"Please circle the weekend
of May 1, 1993. Plan to
celebrate our 50th graduation anniversary. Hope to
see you there."
MORRIS UNHER, M . D .,

"Half a century - our 50th
Reunion! A special time for
all of us. We want to see
you. Please try to make a
special effort to attend."
R ICHARD

J.

CO-CHAIRPERSON

"]oinusforthecelebration!"
IVAN L . BUNNELL, M . D .,
CO-CHAIRPERSON

CLASS OF 1948

"Don't miss our 45th. We
need you to make it a success. Please come. We can
promise a happy time. "
HAROLD L. GRAFF, M .D. ,
CO-CHAIRPERSON

"Two-thirds of us made it to
the last reunion. Hopingfor
100 percent attendance at
our Spring Reunion!"
DANIEL

J.

FAHEY, M . D .,

CO-CHAIRPERSON
BUCKLEY,

M . D ., co-CHAIRPERSON

IN

MEMORY

Long-time Reunion
Co-Chairperson of the
March Class of 1943,
William H. Georgi,
M.D. , died last July
after a long illness.

CLASS OF 1958

"Our 35th Reunion will take
place on May 1,1993. Mark
your calendar, reserve the
date; great plans are underway! We look forward to
seeing you."
M ICHAEL T . GENCO. M . D .,
CO-CHAIRPERSON

I

ALFRED M . STEIN , M . D .,
CO-CHAIRPERSON

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CLASS OF

1973

CLASS OF

"It's hard to believe that 20
yeras have elapsed since we
graduated. Now that we're
all settled and 'huge successes,' let's get reacquainted
at Spring Clinical Day this
coming May."

1988

"May 1st- Our Five Year
Reunion. Don't miss out on
the fun for everyone!"
FRANK A . LUZI , M .D ., CoCHAIRPERSON
LORI GUTTUSO-LUZI ,

M.D. , CO-CHAIRPERSON

MICHAEL A . SANSONE,
M . D ., CHAIRPERSON

CLASS OF

1963

1 968

CLASS OF

"Put the routine aside for a
weekend. Come back and
enjoy the warm companionship and memories of your
classmates and friends at
our 30th Reunion. "

"It's hard to believe that it's
been25 years since we went
our separate ways. We
really would like to see a
tremendous turnout on May
1,1993. Come together and
relive some of the special
times we all shared. Please
try to join us and make this
a truly memorable time for
all of us."

ANTHONY M . FOTI , M.D. ,
CO-CHAIRPERSON

"Each reunion has been rewardingtoall who attended.
Let's make our 30th the best
yet! Reserve the weekend of
May 1, 1963 and renew our
friendships. Makeourday!"

THOMAS J . CUMBO, M . D .,
CO-CHAIRPERSON

"We are lookingforward to
seeing you for our Silver
Anniversary!"

JOHN R . FANELLI , M .D .,
CO-CHAIRPERSON

ROBERT A. MILCH , M .D .,
CO-CHAIRPERSON

CLASS OF

1983

"Let's get together and renew our friendships at our
lOth year reunion."
RICHARD L. COLLINS ,

M .D ., CO-CHAIRPERSON

"/ am really lookingforward
to getting together with those
we have lost touch with. I
hope you all make it!"
JAMES G . CORASANTI ,

CLASS OF

1978

M .D ., CO-CHAIRPERSON

"Medicine's changed a lot in
the past 15 years. Let's get
togetherfor Spring Clinical
Day and see how much we've
all changed. Looking forward to seeing all ofyou in
May of'93!"
STUART L. DORFMAN ,

M .D ., CHAIRPERSON

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•
172

19

Connecticut ••••...•••••••••.• 123
District of Columbia •••.•••• 19
he 4,924 graduates ofUB's School ofMeclicine Delaware ........................ 9
and Biomedical Sciences are scattered far and Florida ......................... 270
wide across the United States.
Georgia •.•••••••••••••••••••.••• SS
Here, Buffalo Physician lists its medical Hawaii .......................... IS
school graduates state-by-state and in the Dis- Iowa ............................... 6
trict of Columbia and Puerto Rico. The ll Idaho .............................. ]
alumni listed in the "Other" category represent physi- Illinois ........................... 63
cians in Canada, England, Africa and other countries.
Indiana .......................... 22
Alaska ••••••••••••.••••••••.••••••• 2 Arizona ......................... 84 Kansas ............................ 8
Alabama ........................ I 0 California ••.••••.••••.••••••.. S02 Kentucky ....................... 20
Arkansas ••.••••.••••.•••••••••••• 4 Colorado ........................ 48 Louisiana ...........•••••••••••• 17

Mapping our medical alumni

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Massachusetts .•..••••••••• 172
Maryland ..................... 16S
Maine ............................ 36
Michigan ........................ 6S
Minnesota ••..••••••••.•••••••• 3S
Missouri ••.•••••••••••••••••••.• 20
Mississippi ••••...••••••••••••••• 3
Montana .......................... ]
North Carolina ••••••••••••••• 66
North Dakota ••••••••••••••••••• S
Nebraska ......................... 3
Nevada ••••••••••••••••••••••••. 22
New Hampshire •••.••••••••• 26
New Jersey •••••••••.••••••• 119
New Mexico •••..••••••.•••••• 18
New York •••.••••••••.•••• 2,06S
Ohio ............................ l36
Oklahoma •••••••••••••••••••••• II
Oregon .......................... l2
Pennsylvania •••••..•••••••• 239
Puerto Rico •••.•••••••••••••••••• S

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Rhode Island •.••••••••.••••••• 33
South Carolina •••.••••••••••• 29
South Dakota •••••••••••••••••• 1
Tennessee ••••••••••••••••••••• 19
Texas ............................ 91
Utah ••••••••••••••••••.•••••••••• 11
Virginia ••••••••••••••••••••••• II 0
Vermont ••••.•••.••••••••••••••• 13
Washington ••••.•••••••.•••••• SO
Wisconsin •••••••••••••••••••••• 27
West Virginia ••••.••••••••••• II
Wyoming •••••••••••••••••••••••• 4
Other ............................ 11

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............................ . ............. . . . ............................. . . . .. . ....

. .

....

I

niversary with a cruise from

IRA L . SALOM '77 ,

Venice to the Black ea and the

june 1992, I received a Master of

Mediterranean. "

Science in Management from the

writes, "In

s

Wagner Graduate School of Public Service, ew York University.

an-

I had been enrolled in the Ad-

nounces his retirement after 30

vanced Management Program for

1

9

5

JOSEPH 5 .

0

DAVID '53 ,

years in practice at Children's

Clinicians, a W. K. Kellogg Foun-

Hospital in Orange, California,

dation-sponsored program in

where he served as chief of sur-

health care policy and manage-

gery and chief of staff. He now

ment studies."

resides in Sun Valley, Idaho.

John Ambrusko '37

1

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6

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Harry L. Metcalf '60,

9

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MICHAEL D . RUDN ICK '87 ,

of
ew York, was

fellows named by the College's

completed a fellowship in Adoles-

Board of Chancellors during their

cent Health in 1991 and was ap-

elected president of the American

annual meeting held in Septem-

pointed director of the Westside

cepted an appointment as surgi-

Academy of Family Physicians

ber in Phoenix, Arizona.

cal consultant for the Qualitative

Foundation.

HARRY L . MET CALF '60,

1

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JOHN AMBRUSKO '37 ,

Williamsville,

has ac-

Assurance Program at Manatee
Memorial Hospital in Bradenton,
Florida.

ROB E RT

BARRYS. 5HULTZ '68,
J O RDO N

'65 ,

chairman of dermatology at The

Ambrusko served as

University of Texas Medical

medical executive director of the

School at Houston, was elected

Manatee County Public Health

chairman of the National Advi-

Department from 1977 to 1990.

ofWest

Reading, Pennsylvania, has been
elected president of the Urological
Association of Pennsylvania .
Shultz is chief executive officer of
Genito-Urinary Associations, Ltd.

sory Board for the National Insti-

The Doctor john Ambrusko Public Health Complex is named in

tute of Arthritis, Musculoskeletal

his honor. From 1950 to 1977,
Amrusko served as chief of surgery and chief consultant in surgery at Kenmore Mercy Hospital ,
Kenmore,

E.

Teen Clinic of Denver's Health

ew York.

1

9

7

s

0

and Skin Diseases. Jordon also

THO MAS

serves on various commiuees and

'71 ,

boards of such professional orga-

profes or of pediatrics and ap-

G E RALD DISESSA

was recently promoted to

and Hospital System. His wife,
Ann Smith-Rudnick '87, is in private family practice.
JOHN CLAUDE KRUSZ '83,

is

on the executive board of the
orth Texas Multiple Sclerosis
Society and has served as chairman of the Professional Advisory
Commillee for three years. He
has a private practice in neurology in Dallas.

nizations as the ociety for Inves-

pointed division chief of pediatric

tigative Dermatology and the

cardiology at the University of

American Academy of Dermatol-

Tennessee College of Medicine,

writes, "Marc Levine '83 and I are

DEBORAPH L. FELDHEIM '84 ,

FRANK T . RIFORGIATO '39 ,

ogy. He is also chief of dermatol-

Memphis, Tennessee. DiSessa is

celebrating our eighth wedding

retired in january. He informs us

ogy at Hermann Hospital and a

medical director of the cardiac

anniversary and have been living

that he is the last of the Italian-

consultant to The University of

catheterization laboratory and the

in the Washington, D.C., area.

American physicians on Buffalo's
West Side, saying, "there are none
left."

Texa M. D. Anderson Cancer
Center and St. Luke's Episcopal

non-invasive laboratory at
LeBonheur Children's Medical

and psychoanalysis in private

Hospital.

Center.

We are both practicing psychiatry
practice and are expecting our
second child in October."

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4

C HAR L ES J . S MITH '66 , ofBay

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Shore, ew York, has been named

of
West Palm Beach, Florida, writes,
WILLIAM J . FOLLE TTE '42 ,

a fellow of the American College
of Radiology. Smith, selected for

"My wife, Della (Walters) , and I
celebrated our 50th wedding an-

6

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is now
chairman of the section of general

Z I NA

surgery at Scripps Memorial Hospital, La jolla, California.

writes, "After five
years in Iowa (where we had a

DANA P . LAU N E R '73 ,

( DM YTRIJUK)

HAJ -

DUCZO K '84 ,

his contributions to the field of

son, Alex, born in May, 1989),

radiology, was one of 144 new

we're back in Buffalo. I am the

p

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�··· · ···· · ··· ·· ··················· · ··· · ··········· · ·· · ·············· · ·· · ·············· · ····•

•
'

new director of echocardiography

MICHAELJ . 8ARTISS '87 ,com-

1991. Bhayana is currently a third

retired in 1986 from X-Ray Associates, a private practice in iagara
Falls. He practiced radiology at

at Buffalo General Hospital and

pleted a fellowship in pediatric

year resident at Francis Scott Key

was recently inducted as a fellow

ophthalmology at Wills Eye Hos-

Hospital.

of the American College of Cardi-

pital, Philadelphia, Pennsylvania,

ology in Dallas in last March."

I

Children's Hospital and Sisters

and has joined a private practice
in Rochester, New York.

ANDREW FR IEDMAN '85 ,

OBITUARIES

Hospital in Buffalo and DeGraff

CARL A. STETTENBENZ '35,

Memorial Hospital in Kenmore.

of Snyder, ew York, died in Feb-

He is survived by his wife, the

writes, "My wife, Susan, and I

JOHN J . O'BR IEN '87 , has

have two children: jacob, 3, and

started a plastic and reconstruc-

William, l. I started a hand fel-

tive surgery fellowship in Hous-

PAUL V. DOWNEY '36, died

lowship at the University of Pitts-

ton, Texas,aftercompletingagen-

july 20, 1992, in his Kenmore

WILLIAM H. GEORGI '43 , died

burgh july 1, 1992."

eral surgery residency in Buffalo.

home after a long illness.

in july after a long illness.

AMY (MILLER) O 'DONNELL

THOMAS P . SMITH , JR . '87 ,

'85 , writes, ''I'm moving back to

announces the birth of Sean

Buffalo from the University of

Patrick on june 5, 1992. He is

Michigan with my husband jack

welcomed by his sister Megan, 7,

and two children, Sara and jef-

and brother, Tommy, 3 1/2.

former Mary Agnew Cain, a son

ruary, 1992.

and six daughters.

He

Help us find your classmates

frey, and will be on the staff in
endocrinology at VA Medical Center. I hope to get back in touch
with my classmates in Buffalo. "

R ICHARD SCARFONE '87 ,

I
rl

writes, "Karen and I have recently

veryone likes to read about

relocated to Philadelphia and are
expecting our first child in Octo-

LISA BECHTEL '86 , writes, "Un-

ber. In May, I was awarded the

expectedly, I'm back in Las Vegas,

Society for Pediatric Research's

coordinating HIV ambulatory care

Fellow's Research Award for the

at the University Medical Center.

study of the use of corticosteroids

Most importantly, my spouse and

to treat moderate to severe asthma

I have two wonderful daughters,

in the emergency room setting. "

what their fmmer colleagues

r

JJ

Scarfone is an associate professor

Mariah and Rose. "

Medicine at St. Christopher's Hos-

accepted a position as chief of the

pital for Children.

classmates are doing.

division of internal medicine and
assistant director of the residency

HOWARD CHANG '89 , informs

program at Mt. Sinai Hospital in

us that he has moved to Los Ange-

Cleveland , Ohio. Pamies has a

les with his new wife, Dawn, and

faculty appointment with Case

will be beginning a fellowship in

Western Reserve Medical School.

pulmonary/critical care medicine
at UCLA Medical Center.

If you

orthopaedics in the department
of orthopaedic surgery at the
George Washington Medical Center.

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know. just use the attached post card

s

and we'll print the infonnation as

RANJ AN BHAYANA '90, ofPerry
Hall, Maryland, announces the

soon as we can.

birth of a daughter, Monisha Maria
Bhayana, born November 27,

p

h

know where they are and

what they're doing - please let us

JOHN K. STARR '86 , has been
appointed assistant professor of

Buffalo Physician better by

telling us what you and your

of Pediatric Emergency Room
RUBENS J . PAM IES '86 , has

Help us make

are doing.

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Spoonful

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Humor

© Stu

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M.D .

Top 10 things overheard in the OR afternational health care reform
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I've got a plane to catch in 15
minutes, let's get started.

Sw Silverstein, M.D., president of Standup
Medicine Seminars of San francisco ,
Californ ia, lecwres nationwide on the role of
humor in medicine.

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                    <text>State University of New York at Buffalo School of Medicine and Biomedical Sciences, Winter 1993

Problem Patients 8 'A Thorny Issue

�THE BUFFALO
PHYSICIAN AND
BIOMED I CAL SCIENT I ST

\olume 27 -.;umber I
DIRECTOR OF
PUBLICAT IONS (A CT ING)

Dr Carole Smith Petro
EDITOR

-.;anelte Tramont Kolhg. R.:\
ART D I RECTOR
~Ian

J Kegler

ASSOCIATE ART DIRECTOR

Scott Fricker
STATE UNIVERSITY OF
NEW YORK AT BUFFALO
SCHOOL OF MEDICINE
AND BIOMEDICAL
SCIENCES

Dr john -.;aughton \ice President
for Chntcal Affa'"· Dran
EDITORIAL BOARD

Dr john ·\ Richert Chairman
\lr Richard de Asia
Dr \!arlin Brecher
Dr Harold Brad\
Dr. RIChard L Colhns
Dr. Donald P Copley
Dr. Alan j . Dnnnan
Dr. Ttmoth,· Gabryel
Dr. Glen Gresham
Dr. james Kanskt
Dr. Charles \lassaro
Dr. Charles Paganelli
Dr. Luther Robmson
Dr. Thomas Rosenthal
Dr. Saleela Suresh
Dr Bradlev T. Truax
Dr Steph~n Spauldmg
Dr jerome Yates
TEACHING HOSPITALS AND
LIAISONS

Bata\la \A \ledtcal Center
Buffalo General Hospital
\fichacl Shah
Buffalo\',\ \led teal Center
Paula Prdmr
Children's Hospital of Buffalo
Ene Count\ \lediCal Center
\lerC\· Hospital
\hllard Fillmore Hospitals
franl1 Sam
Roswell Park Cancer Institute
Sisters of Charity Hospttal
Dmnis .\ lcCartln
'c The State Lnt,·erstty of""' York
at Buffalo

Buffalo PlnSICian IS published
quarterly b' the State Lni,·ersity of
-.;ew York at Buffalo School of
\ledtcme and BIOmediCal Sctences
and the Office of Publications. It IS
sent free of charge, toalumnt, faculty,
students, reSidents and fnends. The
staff resen-cs the nghtto edtt all copy
and subm1ssion~ accepted for
pubhcauon
\ddrcss quesuono; , comments and
submiSSions to · Editor. Buffalo
Physician. State Lni,·ersitv of "\c,,
York at Buffalo, C~i\'CrSll\
Publications. 136 Crofts Hall, Buffa!~ ,
"o;ew York 1-+260

Send address changes to:

Dear Alumni and Friends,

D

r. Elizabeth Olmstead, an alumna, class of '39, has established a significant endowment designed to support the school's educational efforts m the area of medical
informatics. The endowment principal of$1.5 million will generate an annual income
to support the continued development of computer-assisted learning for medical
students and to deliver ongoing educational information to residents, faculty and practicing physicians in Western New York. We believe this is the first such endowment of its
kind in the United States. Dr. Olmstead has been a loyal, dedicated
volunteer faculty member of the school for man} years. She established this important gift to memorialize the memory of her late
husband, Dr. Ira Ross, who was an engineer at Calspan and who
served as its administrative leader from 1958 until his retirement in
1969. The medical school is committed to expanding Its role in this
important area as part of its commitment to keeping all of its
constituencies involved in ongoing, life-long learning. Under the
capable leadership of Dr. John Loonsk, UB is on the cutting edge of
this Important educational technology. Thanks to Dr. Olmstead, this
program will be enriched and we will all benefit from her generosity and kindness.
On behalf of the administration, faculty and alumni, I am pleased to express our
heartfelt gratitude to Dr. Olmstead.
Sincerely,

J ohn aughton , M. D.
Vice President for Clinical Affairs
Dean, School of Medicine and Biomedical Sciences

Dear Fellow Alumni:

W

e're all excited about a high profile idea that should put your Alumm AssoCiation
in the spotlight again. We have begun accepting contributions to a $1 million
Alumni Scholars Fund to support worthy medical school applicants. This is a way
to consolidate our class gifts so we can all pull together for a highly visible
objective. Dean Naughton has expressed his full support for this major endowment fund
that will accumulate principal over a five-year cycle so that each class has a chance to
participate. The admissions department will assist us in picking two
or three students each year. The awards will be presented at our
Spring Clinical Day reception. We intend to follow our Alumni
Scholars through the school year and keep you informed of their
progress.
Another major innovation for 1993 will be our new Alumm
Achievement Awards, to be presented to a select group ofUB medical
alumni who, although perhaps not universally famous, have nevertheless made their mark in a particular area of medical endeavor such
as research, teachmg, technical innovation, private practice, community service and school administration. We are soliciting nominations from all over the
country including both rural and urban locales. These Achievement Awards will be
presented at our Spring Clinical Day luncheon.
We are also sponsoring a Visiting Alumni Lecture Program to encourage the return of
qualified alumni to lecture to peers, residents and students. We will contribute an
honorarium to defray travel expenses. We also plan informal receptions to allo"" the
lecturers a chance to meet old and new friends.
Yours truly,

Buffalo

Plnsician. 146 CF~ \ddnion, 3435
\lamStreet , Buffalo, :\c" York 14214

Don Copley, M. D., '70

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Hospital News
I

Problem'Patients e T:Pe experts sa managing
them takes a :mu self- Xami ation as
patient-exami ati9n.

Taking the Stand e As the need for medical experts
In courtrooms grows, and in the absence o( stand,ardiz-ed pro(essional guidelines-, testifying in court
can be a contro ers~al practtce.

ASpoonful of Humor
Medi,al s,hool
People
Alumni
NCI' s Breast Cancer
Prevention Trial still
open to area women.
Poge 2.

Classnotes

fflillarn ann
~r~lin forge

joint seruice
agreement.
New findings on electric blanket use and breast cancer. Page 2.

rage~-

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....................................................................................

Overall, electric blanket use did not
increase the risk of breast cancer, the
study found. But there was a slightly
elevated, although not statistically significant, risk associated with sleeping with
the blanket on all night throughout the
season, suggesting the need for further
study. Vena continues to investigate the
risks of electric blanket use among premenopausal women.

Electric blankets do not
increase breast cancer risk
urling up under an electric blanket
ward off winter's chill may not
pose an increased cancer risk , according to UB researchers.
john Vena, Ph.D., and colleagues
in the Department of Social and
Preventive Medicine have shown that using an electric blanket does not increase
the risk of breast cancer in post-menopausal women, the population group most
likely to develop the disease.
The study was published in the Americanjournal of Epidemiology.
The breast cancer investigation compared electric blanket use over 10 years in
382 post-menopausal women with the
disease and 439 with no known cancer.
Scientists have hypothesized that chronic
exposure to electromagnetic fields , such
as those produced by electric blankets,
increase breast cancer risk by suppressing
the normal nighttime rise in the level of
. the hormone melatonin. Melatonin regulates the hormone prolactin , known to
influence breast cell growth.
to

6

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BY

LOIS

The study is designed to determine
whether the drug tamoxifen is effective in
preventing breast cancer in women at a
high risk of developing it. Tamoxifen has
been used for 20 years to treat patients
with advanced breast cancer. Since 1985,
it has also been recommended as an adjuvant therapy for early-stage breast cancer.
"With the latest statistics showing that
one in eight women will develop breast
cancer at some time in her lifetime, the

BAKER

Breast cancer
study open to
WNY area
women
he Breast Cancer Prevention Trial announced last April by
the ational Cancer
Institute's ational
Surgical Adjuvant
Breast and Bowel Project is
still accepting women in
Western New York.
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�... . .... . ................................................................. . ..............

tamoxifen
study could
potentially mean the reversal of
this frightening trend and the saving of thousands of women's lives,"
said Stephen Edge, M.D., chief of
breast surgery at Roswell Park
Cancer Institute's Breast Center.
The study will involve
16,000 women who will be
randomly assigned to either tamoxifen or a placebo.
Women 60 years and older are
eligible to participate in the study
based on age alone. Women aged
35 to 59 arc eligible to participate if
they have an increased risk for
developing breast cancer
based on certain factors.
Western
ew York
women interested in participating in the study or
obtaining further information should contact
Roswell Park Cancer Institute at845-7667.

opinion turned up first
on the list.
\

ommunities trying to attract family physicians may get better results if they woo the doctors'
spouses rather than the doctors
themselves, a UB researcher has
found.
ln a survey designed to determine the
factors that influence a doctor's decision
concerning where to practice, the spouse's

u

0

0

p

Personal income , on
the other hand, ranked

lOth .
Results of the survey cond uctcd by Thomas Rosenthal , M.D. , associate professor
of family medicine, were reported in the
journal of the American Board of Family

Spouse's opinion means
most in practice location

B

'
'

h

Practice.
Family practice is one of the most heavily
recruited specialties due to existing and
projected shortages of primary care physicians, a diminishing number of medical
school graduates entering these fields and
a high turnover rate among those who do.
To better understand why a family physician selects one community over an-

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other ,
Rosenthal surveyed physicians
who graduated from
family practice residencies between
1970 and 1989. Data were analyzed
collectively, as well a by year of graduation , community size and in-state versus
out-of-state location.
The survey asked respondents to rank
24 factors known to influence a physician's
decision about where to practice.
Spouse's opinion was rated "most important" or "important" by 86 percent,
with little change across year of graduation, community size or other variables.
"Public policies and medical school
experiences can have an impact on physician specialty and distribution ,"
Rosenthal said , "but the ability of an
individual community to attract physicians will rely on how well it can confront
problems and take action."
The next three factors receiving the
highest percentage of importance were
hospital-related - hospital consultants
(73 percent), hospital services (71 percent) and colleague interaction (70 percent). umber five on the list was afterhours coverage with 70 percent.
Other factors rated important or most
important by a majority of doctors were:
quality of schools (67 percent), proximity to hospital (6J percent), family health
and education need (60 percent), personal income (59 percent), employment
for spouse (56 percent) and cultural opportunities (53 percent).
BY

e

LOIS

BAKER

9

9

0

�a

··························································· · ······· · ··············· · · · ···

the hospital's ties with the School of Medicine and Biomedical Sciences, and forging
an agreement that made Millard Fillmore
Hospitals one of the medical school's major teaching affiliates, with 16 residency
programs based there.
jennings was also instrumental in establishing in 1987 the Western ew York
Health Sciences Consortium - an association of representatives from the medical school and its affiliated teaching hospitals, business and government designed to
emphasize the need for cooperation and
enhance the quality ofhealth care in Westem ewYork.
"One of the most rewarding aspects of
my experience in Buffalo," jennings said,
"has been working with the University at
Buffalo School of Medicine and Biomedical Sciences in the formation of the Western ew York Health Sciences Consortium.
"One of the best secrets in Western ew
York is the quiet but measurable leadership of Dr. john Naughton. He has in this
tenure taken the University's medical
school to the top quartile of all U.S. medical schools. In several key areas of measurement, the UB medical school is clearly
within the top lOin thecountry,"jennings
said.
"This achievement is directly related to
Dean aughton's commitment to excellence and perseverance," he added.
Under jennings' stewardship, Millard
Fillmore Hospitals established five primary care sites in medically underserved
areas, established its successful Sleep Disorders and Hand Center specialty services, forged an agreement between its
3,342-birth Suburban Hospital maternity
service and The Children's Hospital of
Buffalo for neonatal coverage, established
its $4.5 million Baird MS research center
and developed the nation's largest freestanding ambulatory care center.
The hospital also recently broke ground
for a $60-million expansion and renovation project. The project, one of the

Jennings leaves Mnlard
post for Chicago ChUdren's
an R. jennings, president and chief
executive officerofMillard Fillmore
Hospitals for the last 10 years, was
recently named president and chief
executive officer of the Chicago
Children's Memorial Medical Center. He took over his new post january 15,
1993.
"Having securely positioned Millard
Fillmore Hospitals to meet the health care
needs of this community for many
generations, the climate was appropriate to accept the position at the Chicago
Children's Memorial
Medical Center, considered the 'crown
jewel' of the U.S. child advocacy movement," jennings said.
"During my nine years as president of
Millard Fillmore, we have achieved every
strategic objective charted. Millard
Fillmore Hospitals has become one of the
leading health care facilities in ew York
State," he said.
"The numerous successes achieved by
Millard Fillmore during these nine years
could not have been accomplished without the cooperation and dedication of the
hospitals' board of directors, medical and
nursing staffs, administration, employees
and volunteers," jennings added.
jennings took over as president ofMillard
Fillmore Hospitals in 1983. The twohospital system had, at the time, lost $20
million over the previous l3 years. With
several additions to a newly built administrative team, jennings turned Millard's finances around, with it emerging as the
only major teaching hospital in the state to
have maintained a positive bottom line for
the past eight consecutive years.
jennings is credited with strengthening

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largest in its history, includes the addition
of 43 beds to Millard Fillmore Suburban
Hospital and major renovations to both
the Gates Circle and Suburban facilities.
The Chicago Children's Memorial Medical Center, founded in 1882 for poor children and affiliated with orthwestem
University Medical School, is a multicorporate entity with its 265-bed facility
as its centerpiece.
A national search to find a new presidentand chief executive officer for Millard
Fillmore Hospitals is already underway.

New surgery chief named
at VA Medical Center
illiam Lynn Weaver, M.D.,
has been appointed clinical
associate professor of surgery and chief of surgery at
Buffalo VA Medical Center.
A native ofKnoxville, Tennessee, Weaver graduated from Howard
University in Washington, D.C. , with a
degree in pharmacy. He attended Me harry
Medical College in ashville and completed his internship, residency and nine
years in the Army.
"I think this is a tremendous challenge
because of the history of the surgical department of this VA and all it stands for ,"
Weaver said. "The important name that
the Buffalo VA and University at Buffalo
medical school have developed in the national medical community gives me the
opportunity to work with some of the
brightest minds in the country," he added.
Weaver hopes to increase the visibility of the surgery department by highlighting some of its
past accomplishments, including its
leading role in the
development of cardiovascular technology.
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Sisters Hospital announces
change in leadership
isters of Charity Hospital has announced that Sister Angela
Bontempo, hospital president and chief executive
officer, is leaving Sisters
Hospital for other duties
within her religious order, the
Daughters of Charity of St.
Vincent De Paul.
With the change in Sister
Bontempo's status effective in October, a search process for a new
chief executive officer is now underway under the direction of the
regional office of the Daughters of
Charity National Health System.
"Being missioned is part of life
in our religious community," Sister Bontempo said. "I've been at
Sisters Hospital for six years and
that's probably about an average
stay for sisters in our order. But
whether it's six, 16 or 60, moving
on is never easy," Sister Bontempo
said.
"I will carry Buffalo and its
people in my heart, always. Like
so many others who have come to
this beautiful area, Buffalo has captured me and I'll always be a Buffalo booster."
Sister Bontempo took over Sisters Hospital in December 1986. "When I came
here," she said, "the hospital needed major work. We had an old facility that
begged for attention and was dangerously
close to slipping into financial disaster. "
Sister Bontempo brought in a new administrative team and the hospital has
finished every year of her tenure with a
positive bottom line while its fund balance
has doubled.
Among her accomplishments have been
the establishment of new women's services, satellite primary care and chemical
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In 1990, Gov. Mario Cuomo named
Sister Bontempo to the ew York State
Pubic Health Council. She was also
named to the Board of Trustees of the
Western ew York Public Broadcasting
Association.

dependency centers and the hospital's $42
million modernization project, slated for
completion in 1994. The project includes
a new emergency department, family care
center, operating rooms, intensive and

-----

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Mnlard and BryUn
announce ioint
service agreement
illard Fillmore Hospitals and Brylin
Hospitals recently
announced the establishment ofa formal medical ser-

vices exchange agreement and
the appointment of a jointly
recruited physician to head
Millard's psychiatry department
and serve as associate medical
director at BryLin.
The agreement provides psychiatric consultation services
for all emergency room and
inpatients at Millard's Gates
Circle and Suburban facilities
and inservice educational programs for the nursing and support staffs. It also will foster a
more coordinated care effort for inpatients at Brylin who need acute medical
care and treatment.
Under th e agreement, Ellen S.
Dickinson, M.D., clinical assistant professor of psychiatry, was named chairperson
of Millard's psychiatry department and
associate medical director at BryLin.
Board certified in psychiatry and neurology, Dickinson was an assistant professor of psychiatry at Albert Einstein College ofMedicine, Yeshiva University, ew
York. She also served as the unit chief of
psychiatry at North Central Bronx Hospital in ew York.

coronary care units, head and neck center,
urology and ambulatory care areas as well
as a new entrance way and lobby.
Sister Bontempo was the first woman to
serve on the board of directors of M&amp;:T
Bank and currently sits on the board of the
bank's parent company, First Empire State
Corporation. In 1987, she received the
Clifton C. Thorne Award for outstanding
achievement in health care and human
services.
She received the 1989 Brotherhood!
Sisterhood Award in health care by the
National Conference of Christians and
jews.
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Problem Patients
Every
physician
has
themhere's
how
he patient, a

some
doctors

woman, came to Suzanne K.W. Anderson, M.D., with
a complaint beyond the l&lt;en of any diagnostician.

deal

"I feel

with

"I just feel so empty."

empty inside," she said.

them.

Then she came again. And again.
Soon, the patient was seeing Anderson every couple
of days. "She really glommed onto me," says Anderson, now a family phy~ician and a clinical assistant
professor of family medicine at the UB medical school.
"She told me I was the only doctor who would ever tal&lt;e
care of her, who would ever love her."
Buff

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�Anderson tried to set limits- and the
young woman turned violent. She cut
herself with razor blades, showing the
doctor her scars as punishment for her
"rejection. " She invented a wild story
about being kidnapped and raped, saying
the rapist had carved an obscenity into her
abdomen.
The word was there, all right, but it was
the woman's own knife that had done the
carving.
"Over time we did manage to establish
some limits and got her into counseling,"
Anderson says. "And she actually ended
up having astable relationship with a man
after a couple of years."
Problem solved.
But for physicians struggling to treat
difficult patients, rarely is the solution so
neat. From dependent, fawning persons
to the hostile and delusional , problem
patients are a continual source of frustration for the caring doctor. Treating them
means negotiating a fine line between
empathy and effectiveness. And, perhaps
most difficult to acknowledge, problem
patients can point up a physician's own
subconscious prejudices and shortcomings.
"In a way, every patient is potentially a
problem patient," Anderson says. "If their
problems aren't treated respectfully, they
can be a problem."
"Compassionate objectivity" is how
Jamie Shiffner defines that line between
getting too involved with a patient and
staying too distant. Too close, he says,
and the physician can get caught up in the
patient's emotions and stresses. Too far ,
and it's impossible to treat a patient with
the empathy essential to proper diagnosis.
Shiffner, a psychologist with a doctoral
degree, teaches a Behavioral Sciences Seminar in the medical school's Department of
Family Medicine. As part of that seminar,
he delivers an annual lecture on problem
patients- who they are and how to cope
with them. There are no easy answers; the
lecture consists of a series of video clips of
patients, followed by students' discussion

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hysician A might have no
problem with a patient
Physician B finds
highly annoying- a
difference that's rooted in
the doctor's own subconscious.
"There are certain kinds of personalities
that we have trouble with, just because they
remind us of people we've had bad experiences
with in our own lives. You can use your own
response as a diagnostic tool."
of how they might handle the situation.
One thing he has discovered, Shiffner
says, is that "Know thyselr' is the first rule
for dealing with problem patients.
"Rather than being focused outwardly,
pay attention to yourself," he says. "Know
when you need to excuse yourself and get
a cup of coffee, then come back. ... Give
yourself time and space. Often it feels like,
'I've got to do this now, in my office, this
second.' But there are very few things
other than a code that you have to do right

people who are excessively concerned
about why I'm prescribing this drug, and
does it have side effects. I also have a
problem with excessively dependent
people, and I can use my own annoyance
as a signal that this is a dependent person.
You can use your own response as a diagnostic tool."
One place where problem patients congregate is hospital emergency departments.
Close to the street, often serving as primary care providers for people without a
regular physician, ERs play host every day
to a wide-ranging drama of human misery.
"There are hundreds of different reasons that people have stress that may
ultimately result in a visit to the emergency department," says Steve Lakomy,
M.D., who practices in three Western ew
York ERs - at St. joseph and Sisters
hospitals and the Erie County Medical
Center-and is a clinical assistant professor of emergency medicine at UB . "There

now. "

Anderson notes that Physician A might
have no problem with a patient whom
Physician B finds highly annoying - a
difference, she says, that's roo ted in the
doctor's own subconscious.
"There are certain kinds of personalities that we have trouble with,just because
they remind us of people we've had bad
experiences wi th in ou r own lives," she
says. "I tend to have a problem wi th
people who challenge authority a lot -

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�are people who come to the emergency
department because they're depressed and
have a physical manifestation. Or they
have a lot of stress at home or on the job,
and they come in with an ulcer or high
blood pressure.
"There are people who just have emotional insecurity and can't deal with their
problems; they don't have the coping
mechanisms. It's a very wide range of
people, and a wide range of problems. We
kind of lump all these people together as
hypochondriacs, when in fact there are all
sorts of reasons. "
One problem endemic to emergency
rooms is the drug-seeking person. 'Tve
had a patient come in and complain of a
crushing chest pain, and gave him morphine for what could have been heart
attack pain," Lakomy says. "It turned out
he was faking it.
"Or you have people from out of town
who present with pain and say they need
Demerol. But most area little more tactful.
They have a whole list of drugs they can't
take because (they say) they have an allergic reaction. Basically, it narrows down to
one or two narcotics that they can take.
"Sometimes they walk out of the department when they realize you're not just
going to give them medication.
"Butl always try to err on the side of the
patient. l would rather be fooled several
times, and actually give narcotics to a
patient who's not being honest, than send
somebody home in pain."
Then there are the characters - not
too sick, not too crazy,just enough of both
- who keep life in the ER interesting.
Lakomy tells of one patient, an asthmatic
man in his late 40s, who sometimes shows
up every day for two weeks with an exacerbation of his condition. While he's
being treated, he regales the staff with his
intentions to marry famous exMouseketeer Annette Funicello - who,
of course, knows nothing of the sort. But
he has this plan, see ...
The patient has refused psychiatric
counseling, Lakomy says, "but he's still a
very functional individual."

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here~

a reporting system for doctors -

if we commit a violation or have a
lawsuit against us, it gets recorded
and gets reported to the physician registry. But patients who have seen doctors multiple times or who have had
multiple surgeries, and never had any
positive findings - we don't know about those
patients. We become their victims."
Anxiety, in all its forms, surfaces again
and again as an underlying cause of patients' problem behaviors. Anderson, the
family physician, tells of a recent patient
who imagined that his head was Ooating
up to the ceiling, and that electric shocks
were shooting from his head to his toes
and out his anns.
Such symptoms, she noted , don't correlate with any known organic illness. So
she spent some time talking with the patient. lt turned out that he had recently
emigrated from Cuba, had a big family to
support, had no job and no health insurance. "The symptoms were all related to
this tremendous anxiety he had," Anderson says. "The thing is, he had been to an
internist who had put him through a whole
lot of tests, and spent a lot of his personal
money, without result. "
ln such cases, she says, "it's really a
challenge to get them to see they don't
have a physical illness. You have to bring
this on very slowly and carefully, not too
abruptly.
"Often, just the awareness (that the
symptoms are anxiety-related) makes the
symptoms disappear or become a nonconcern to the patient."

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Dentists, especially, find fear and anxiety epidemic among their patients- often stemming from fear of the dentist
himself. The effects can be crippling.
SanfordL. Nusbaum, D.D.S. ,a l960graduate of the UB dental school, tells of one
patient.
"Open, please," Nusbaum said to the
patient, who would not.
"We talked about it. l said, 'Can you
open7'
'"Yes.'
"'Do you want me to examine you and
see what the problem is?'
'"Yes.'
'"Well , open.'
'"I can't."'
'Tve seen patients that, when you start
explaining to them what has to be done,
they'll pass out just listening to it. There's
all this psychological, emotional baggage
they're carrying with them that makes it a
problem.''
Despite the time pressures on every
physician, Howard Lippes, M.D. , '77, a
clinical assistant professor of medicine at
B, says the doctor's time is what fearful
patients need most.
"If you can possibly spend the time to

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"

many problem patients who ought to be problem
patients, because they're not given the information
that the patient should be receiving."

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"If you can't find something physically patient on, you're almost acknowledging
wrong with them, they're almost angry at the wrongs of the prior physician."
you . And they'll go to another doctor.
All this is moot, he says, if the patient is
"There's a reporting system for doctors not physically ill. Abandonment is rarely
- if we commit a violation or have a charged, he says, "but physicians worry
lawsuit against us, it gets recorded and anyway."
gets reported to the physician registry. But
Also , Albert notes, "Not all problem
patients who have seen doctors multiple patients are in the wrong. There are many
times or who have had multiple admis- problem patients who ought to be probsions and multiple surgeries, and never lem patients, because they're not given the
had any positive findings - we don't information that the patient should be
know about those patients. We become receiving. "
their victims. "
And just because a patient presents sympCan a physician who finds a patient toms that have grown in the mind, endocriunbearable sever their professional rela- nologist Lippes notes that doesn't mean he
tionship? The answer is yes, but the isn't sick in body anyway. He tells of a patient
legalities can be dicey.
he saw while an intern- "an elderly woman
UB Law School Professor Lee A. Albert, who complained of chest pain on a daily
a specialist in medical-related legal issues, basis. All the physicians who took care of her
says ending a doctor-patient relationship were rather exasperated; her pains were atis legally risky when the patient is ill and tributed to depression.
has nowhere else to go.
"But one day she explained that her
"A doctor may not deny services to that chest pain was really due to a heart attack.
patient without being sure the patient has And it really was. The attending physician
access to a substitute physician," Albert told me, 'Even the crocks get sick somesays. "If she does refuse services after a times.' The lesson being that even the
patient-physician relationship is estab- hypochondriacal patients can get real illlished, without reasonable assurance that nesses. You really have to be tuned in."
a substitute physician is available, that's
Despite the frustrations , Campagna and
called abandonment, and it's tortious con- other physicians say dealing with problem
duct. The patient can sue for damages. " patients is just part of the territory in a
But,Aibertsays, "reasonable assurance" human science like medicine. "If you
is a gray area. "It's often not very easy to conquer the challenge and ultimately
find a substitute. When you go to a new things turn out well for them , it's a victory
doctor, he asks whom you've been treated and it's a wonderful feeling," she says.
by and what happened. There's a kind of "But sometimes the pain of getting there is
collegiality that says if you do take that more than you want to bear."

sit down and explain to the patient what it
is you're doing or what it is you think the
patient has, you're most of the way there,"
Lippes says. "The more suspicious and
anxious the person is, the more time it
takes."
But the physician can talk until he's
three shades of blue, and he won't talk
some patients into doing what's best for
themselves.
on-compliance, or nonadherence, is one of the thorniest issues
confronting physicians with a sincere interest in their patients' well-being.
Ida M. Campagna, M.D ., '79, apracticing OB/GYN who is a clinical assistant
professor in UB medical school's Department of Gynecology and Obstetrics, cites
the case of a young patient she has now:
pregnant, diabetic, but who refuses to take
insulin.
"We're going to try to do some outreach to this girl," Campagna says. "Get
on the horn, call her, see if we can convince her how serious this is. A lot of
things can happen with this baby. You
have to pull at the heartstrings of the
mother and say, This is what's best for
your baby.'
"Sometimes you have to do what your
mother did, which is to administer an oldfashioned dose of guilt."
Campagna also says she is troubled by
"doctor-shopping," where patients go to
one physician after another in search of a
diagnosis that fits their own idea of what's
wrong. "There are people who are really
delusional about their ailments," she says.

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�'A roster of difficult patients
Jamie Shiffner, a psychologist with a
doctoral degree who teaches a Behavioral Sciences Seminar in the UB medical school's Department of Family
Medicine, delivers an annual lecture
on problem patients- who they are
and how to cope with them.
Shiffner has summarized the range
of problem patients - a range as
broad as humanity itself - into a
dozen categories. They're a laundry
list of the people who can ruin a
physician's day. Perhaps you've encountered:
Overly dependent people who
have trouble making decisions .
"They're the ones who call up at 3 in
the morning and say, Tve got a runny
nose, do you think I should take an
antihistamine?'" Shiffner says.
Seductive patients, both those
who approach a physician sexually
and patients who wheedle and flatter the physician in order to obtain
narcotics.
Aggressive patients. "Some get

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downright nasty," Shiffner says.
Threatening people, who know what
they want- for the doctor to sign disability papers, for example - and threaten
force to get it.
Suicidal or self-mutilating patients.
Antisocial personalities, whose problem behaviors include lying, cheating and
stealing. One antisocial patient is the one
who never pays his bill.
Patients who withhold necessary information, out of distrust or shyness.
"Sometimes," Shiffner says, "people expect that doctors should be magical, and
figure out what's going on without any
information."
Those with psychotic delusions. Arguing logic with them gets the physician
nowhere.
Passive-aggressive persons - tho e
who say yes but mean no. Into this category fall all those patients who say they'll
take their medication , lose weight, whatever, but don't follow up.
People who are disgusting for some
reason. Their appearance may just pro-

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voke strong emotion in the physician -or they may not have showered in weeks. "They can be lovely
people," Shiffnersays, "but it's really
hard if you can't sit there without
passing out from the aroma."
Extremely attractive people.
"Feelings don't just go away because
you're a doctor," Shiffner says.
And finally, patients suffering
from a borderline personality disorder, generally people who have been
abused as children. These patients,
Shiffner says, are both dependent
and standoffish - a contradictory
set of behaviors difficult to resolve.
In addition, Shiffner mentions a
seemingly innocuous behavior that
can turn into a problem: the patient
who's exceedingly nice. "Maybe they
talk and talk," he says; "maybe it's
hard to deliver difficult news to them.
What if you have to talk to them
about their drinking too much? That
can be as difficult as the person who
comes in and yells at you."

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��BY

ANDREW

DANZO

he said he raped her. He said she consented.
The physical evidence couldn't say who was
telling the truth.

Thats where Raphael S.

Good, M.D., came in.

"My testimony was

that the way she described the event, rape was
not possible -

or at least entry was not

possible," recalled the University at Buffalo
medical school graduate. "That was the bottom line. "

He never said in so many words

that William Kennedy Smiths accuser was
lying, but Good gave the jury in West Palm
Beach, Florida, reason to doubt her. And in
December 1991 , thefourwomenandtwomen
found Smith innocent.

I)hysicians (L' I
ILLUSTRATION

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�Lastly, taking the stand isn't always
fun.
"It's very intimidating to be a witness,"
said Brian S. joseph, M.D., a psychiatrist
who graduated from the UB medical school
in 1968. "You're playing by different
rules, and while they're always respectful,
they don't always treat you like you know
everything."
But the American College of Physicians maintains testifying in court is part
and parcel of a higher calling. In its 1990
statement, which accompanies guidelines
for medical expert witnesses, the college
said: "Physicians, as members of society
and as professionals, have a duty to testify
in court as expert witnesses . . .. Nonpartisan and scientifically valid expert testimony not only assists the deliberations in
a particular case, but also can establish for
the record applicable standards of care."
Some physicians say an occasional
court date can be a gratifying teaching
experience that helps keep them sharp.
Others say there are personal rewards,
especially in medical malpractice cases
where they can help weed out incompetents or come to the aid of a wrongfully
accused colleague.
And, while it's not for everyone, cross-

be to get more physicians into the courtroom.
"Small numbers of physicians should
not spend disproportionate amounts of
time testifying; rather, more physicians
should try to be available to serve as experts as a component of their professional
activities," the American College ofPhysicians proclaimed in a 1990 statement.
How can practitioners obliger
"They might make it known to their
local medical societies," said Lois Snyder,
].D., manager of health and medical-legal
policy development for the college. "Some
societies are becoming interested in pulling together an information bank of people
who could be experts."
But, she added, "I don't know who is
doing this with regularity. "
Physicians have plenty of reasons for
avoiding the courts. Many cite the time it
takes from their already busy schedules.
And things can get messy if arrangements
with the lawyer aren't spelled out. In
Buffalo, so many disputes over issues like
fees and canceled court dates have arisen
that the county medical society has been
working with the local bar association to
develop a model witness agreement for
members.

ood is among the large
number of physicians
who go into the courtroom as expert witnesses.
Many more serve as experts in cases that never
reach court, either because the cases are settled
beforehand or because the
physicians convince the
lawyers that there really
isn't a case.
Many lawyers say their
need for medical experts
has grown, and with that
growth has come controversy. Court rules for the
use of medical experts are
vague, and professional
guidelines vary among
different medical organizations. Some physicians
turn up so frequently on
the witness stand that they have little or no
time to actually practice. Some of their
colleagues refer to them as "hired guns,"
the medical equivalent of the ambulancechasing lawyer.
The best way to reduce the reliance on
experts with questionable expertise may

"THE PEOPLE
WHO TESTIFY
FREQUENTLY,
MANY OF US
THINK OF THEM
AS WHOREs.••
Rapna I(, t&gt;d \1 D.

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�"YOU'RE PLAYING
BY DIFFERENT
RULES, AND
WHILE THEY'RE
ALWAYS RESPECTFUL,THEY
DON'T ALWAYS
TREAT YOU LIKE
YOU KNOW
EVERYTHING."

-Bnanjoseplt, M.D.

examination can be as invigorating as a
good game of tennis.
"Listen," said Good. "I don't do anything I don't enjoy. I've been around too
long."
Good, a member of the UB medical
school's Class of 1948, said he was brought
into the William Kennedy Smith case by
defense attorneys seeking a rape expert.
Board certified in OB-GY and psychiatry, both of which he teaches as a clinical
professor at the University ofMiami medical school, Good helped establish one of
the nation's first rape-treatment centers in
Miami in the early 1970s. He also is coauthor of a book chapter on rape.
But Good's testimony ended up centering on the physiology of sexual response,
and for that he was also qualified as a
former vice president of the American
Association of Sex Educators, Counselors
and Therapists, and as the organizer of a
human sexuality course at the University
of Miami. He also maintains a psychiatric
practice in Miami.
Before trial, he reviewed voluminous
records, including the depositions, police
statements and polygraph tests of Patricia
Bowman, the woman who accused Smith.
"I would guess the stack was close to two

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feet high ," Good said.
On the witness stand, he said, he was
given a hypothetical situation mirroring
the alleged circumstances- that the rape
occurred even though the victim was fighting off the attacker, the victim was not
sexually aroused and the attacker had
only a partial erection. Good said it didn't
add up.
Under cross-examination, he said, the
prosecuting attorney kept hammering
away at the fact that there was semen in the
woman's vagina, so there had to have been
intercourse.
"I kept saying that under the conditions described, she could not have had
intercourse," Good said. "The prosecutor
said intercourse did occur. 1 said, 'Well,
there must be some discrepancy."'
The physician said he enjoyed verbally
dueling with the assistant prosecutor who
questioned him.
"She tried to downplay my clinical
experience, saying 1 was busy reviewing
journals and giving talks around the country, implying I was not clinically involved
with patients," Good said. "1answered by
saying, 'Yes, it's true I am a very busy
doctor.' She was very frustrated. "
For all his cool, Good had been on a

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witness stand only twice before. Once he
testified about behavioral responses to
pornography in an obscenity trial, and
another time about marital relationships
in a case involving an abortion law's spousal-notification clause.
Like many medical experts, Good has
worked with attorneys much more frequentlyoutside the courtroom. He said he
is often called upon to review records in
medical malpractice and personal injury
cases, but the cases are usually settled or
dropped before court, based on his conclusions.
Good emphasized, however, that it's
only a sideline. "The people who testify
frequently, many of us think of them as
whores," he said. "It's not an unusual
experience, the same people are testifying
all the time. I'm not sure they are dishonest, but they may see things a little differently."
Few formal restrictions, however, govern the use of expert medical witnesses.
"Generally, the relevant guidelines are
the federal rules that govern court proceedings, and they are very broad about
who can testify," said the American College of Physicians' Snyder. "Physicians
sometimes see that as a problem."

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�Various medical organizations have
their own guidelines. The American Association of eurological Surgeons, for instance, says members who testify should
be practicing surgeons or those who "can
demonstrate enough familiarity with
present practices as warrant designation
as an expert." The American College of
Physicians suggests that witnesses "should
be actively involved in the clinical practice
of the specialty or the subject matter of the
case for three of the previous five years at
the time of the testimony." The Medical
Society of the State of ew York says
witnesses should be practicing in the specialty at issue, but if they are already
retired, it shouldn't be for more than five
years.
Not only do guidelines vary, but there
are also gaps. For example, one pediatrician wrote in a letter to the journal Pediatrics last year that he would like better
criteria for testifying in medical malprac-

"YOU CAN'T
SURVIVE FOR
VERY LONG AS
AN EXPERT
WITNESS IF
YOU'RE A HIRED
GUN, BECAUSE
YOU'D BE
EXPOSED."

They don't teach "Expert Testimony" in
medical school. Yet some believe more physicians should lend their expertise to the legal
system as a matter of professional duty
Here are some tips for those who get involved:
GET IT IN WRITING

Many physicians become expert witnesses on the basis of little more than a
phone conversation. That's a mistake,
because there is ample room for misunderstanding.
The Medical Society of Erie County
and the Erie County Bar Association have
been working on a model document to
use in drafting expert witness agreements.
For more information on the model, contact the medical society at (716) 8521810.
WHAT To CHARGE
A general rule of thumb is, charge
whatever the value of the time taken from
your practice.

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Keep in mind, the American College
of Physicians and others consider it unethical for experts to take a fee contingent
on the case's outcome.
One physician, however, has proposed
an interesting twist on the contingency
fee. In a letter in the May 20, 1992,
journal of the American Medical Association ,]. Terrence Coyle, M.D. , a physician
who practices at the Eye Clinic ofBellevue,
Washington, writes that when he is asked
to review a medical malpractice case and
finds no merit to it, he asks no payment
as long as the case is dropped. That, he
writes, "has saved several physicians unnecessary stress from unfounded malpractice suits."

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PRACTICE WHAT YOU
PREACH

One of the top criteria for a medical
expert is clinical experience in the subject. The American College of Physicians, for instance, suggests active clinical practice for three of the previous five
years.
Consult your state medical society
and your specialty organization -there's
a good chance they also have guidelines.
And once you take the stand:
DON' T SPECULATE

ln the William Kennedy Smith rape
trial, Raphael S. Good, M.D. , testified
that sexual intercourse could not have
occurred under the circumstances de-

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�Lice cases.
lt is unclear how many different professional guidelines have been issued. Only
late last year did the American Medical
Association survey specialty societies to
get a handle on the patchwork of rules.
ln the meantime, the classified pages of
law journals are filled with ads for medical
experts seeking work. One ad in a recent
issue of the National Law joumal states:
"Neurologist. On faculty of prestigious
university. Head injury and other expertise. " The ad lists a Boston-area telephone
number.
There are also services that provide
medical experts. ln another National Law
]oumal ad, the Medsearch etwork lnc.
offers "Prompt initial case assessment$495" for medical malpractice attorneys.
Medsearch advertises that "Our expert
panel consists of 15,000 board certified
medical specialists nationwide" who provide reports, depositions and testimony.

scribed by the accuser. Good says the
prosecuting attorney kept asking how
that could be, since physical evidence
showed that intercourse had occurred.
"The prosecutor would have liked me
to say she (the woman) must have been
lying. Butthat's a trap. Once you say that,
they ask you how do you know someone
is lying," Good recounts. "When they
asked how do you explain it, l said, 'Hey,
there's some discrepancy."'

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ATTITUDE IS EVERYTHING
"You can't be arrogant and you must
understand where you are," advises
Franklin Zcplowitz, M.D. "Many times
they (lawyers) get after physicians that
come into the courtroom with a hostile

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manner."
A past president of the UB medical
school alumni association (Class of'58),
Zeplowitz is a Buffalo surgeon who has
testified in the past as an expert and now
testifies regularly as the treating physician when his patients pursue personal
injury cases.
BE CLEAR

"lt's not unlike giving a lecture to a
class, to the extent they can understand
what you're saying," says psychiatrist
Brian S. joseph, M.D., '68.
"You'vegota lay jury," addsZeplowitz.
"You've got to answer questions at their
level so they can understand what you're
talking about."

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o one suggests that such witnesses
will say anything for a price. But some
question the expertise of physicians who
spend more time in court than at the
bedside. Others point out that in court, it's
not always what you say but how you say
it, and some experts might be more willing
than others to tailor the way they answer
questions.
Good said a close friend of his is an
attorney who handles personal injury
cases. Years ago the lawyer had Good
review a worker's compensation case. "I
told him my opinion," Good recalled. "He
thought I could say ita different way. I did
not feell could say it another way." The
two have remained friends, but the lawyer
has never again sought Good's medical
expertise.
Many attorneys, however, say the only
thing they want from an expert is an
honest, unslanted assessment. Lawyers
are becoming more thorough in research-

COACHING

Lawyers won't tell you what to say (at
least they shouldn't). But they may want
you to emphasize some things and
downplay others. The best way to deal
with the gray areas is to stick to your
notes.
"You just bring the facts out as you see
them," says Zeplowitz.
DON ' T BE FOOLED

Advises joseph: "When you go to
court and the opposing attorney says,
'Good morning, doctor,' it's important to
know he doesn't mean it. "
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••H ..

"OFTEN YOU
ARE CONTACTED
BY ATTORNEYS
BY VIRTUE OF
THE PAPERS YOU
HAVE WRITTEN."

-]ach Fisher, M.D.

ing the history of their opponent's expert
witnesses, and they will seize on anything
that helps them paint the witness as a
hired gun. A lawyer can raise questions in
jurors' minds about a psychiatrist who
always finds criminal defendants insane
or an obstetrician who always testifies for
malpractice plaintiffs but never for defendants.
"You can't survive for very long as an
expert witness if you're a hired gun, because you'd be exposed," said Charles P.
Ewing, J.D. and Ph.D. , a UB professor of
law and psychology who has testified as a
forensic psychologist.
"You want someone who is rigorous
and fair," said Gregory Stamm, j.D., a
Buffalo-area attorney who frequently represents physicians before government
agencies and sometimes represents medical malpractice plaintiffs.
"If you have a doctor who's willing to
testify about gynecology one day and psychology the next day and internal medicine the next day, he's going to be exposed,
so you haven't done yourself any favors
hiring him," said Stamm, a 1971 UB law
school graduate.
Lawyers usually can find experts without
resorting to the full-time professionals.

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"Often you are contacted by attorneys by
virtue of the papers you have written," said
jack C. Fisher, M.D., head of the division of
plastic surgery at the University of California,
San Diego, Medical Center.
Fisher, a 1962 UB medicalschoolgraduate, served as chairman of a Plastic Surgery
Educational Foundation committee on
silicone implants in the late 1980s. He
later wrote about the issue in the New
England journal of Medicine.
ow he is
working with several attorneys defending
physicians against silicone breast implant
lawsuits.
"So when you put a summary of an
issue in the New Englandjoumal of Medicine, there are a lot more eyes on that
summary than just the subscribers to the
journal," Fisher said.
In cases involving quality of care, Stamm
said lawyers first look for experts within
the community who can address local
standards. "If you're representing the
physician, it's very easy to find someone,"
he said. It's much harder to find local
experts willing to testify for plaintiffs
against physicians, he added.
lf no local physicians will testify, Stamm
said a lawyer will look to nearby communities. "What you're looking for is an

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expert who at least practices in the same
state as the defendant," he said.
After a while, attorneys develop their
own lists of experts who are willing to
testify, though they try to avoid using the
same ones over and over. Lawyers will
occasionally give a colleague the name of
one of their own experts as a professional
favor.
In the William Kennedy Smith case,
Good said defense lawyers first enlisted a
friend of his, a pathologist, in their search
for a rape expert. The pathologist called
around the country, unaware that his friend
had a reputation in the field. "People said,
'Hey, there's somebody there in Miami,"'
Good recalled.
In the end, Good said, he felt his testimony carried a lot of weight with the jury.
But, he added, "There were many other
aspects of the case that resulted in the not
guilty verdict, l'm sure."
And Stamm noted that as important as
experts are, they usually don't make or
break a case by themselves.
"Good cases will tend to win regardless
of experts and bad cases will tend to lose
regardless of experts," he said. "I've had
jurors tell me they didn't listen to the
experts."

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�A

Spoonful

of

Humor

©

Stu

Silverstein,

M.D .

hou hts on avisit to our nation's ca ital
Before addressing the physicians of the
D.C. Medical Society, l got to see the
happenings of Washington first hand. l
was welcomed to the D.C. area by all of the
soon-to-be-unemployed Republicans at
the exit ramp holding their "Will forge
passports for food" signs.
After living the past few years in California and growing accustomed to its casual ew Age attire, like tie-dyed lab
coats, l was overwhelmed
by the sea of blue and gray
suits - more than I saw
during the entire 15 days of
the PBS series on the Civil
War.
Aides say they are concerned with how Bush will adjust to just sitting around with no
defined job or agenda doing nothing
during the next few months. Cmonhe's been doing that for the past four
years.
Bush is getting ready to move
out. Barbara is out house-hunting
for a nice place in George's hometown ...
just as soon as they figure out which state
it is in.
Secretary of State james Baker, who has
always bolstered his career by associating
with winners,justsigned on as the mascot
of the '49ers (sorry, Bills fans!).
The Democrats are taking over the city,
and with President-elect Clinton's drive
for ethics in government, startingjanuary
20th you could easily get pulled over for
driving under the influence of a lobbyist.
ow, Arkansas "chic" is in. (An oxymoron, like congressional ethics.) l caught
an early sign of this when I saw a young
civil servant drive by in a Chevy pickup
with a wine rack on the back.
Clinton says he will involve Americans
from all sectors of society in his administration. He's considering giving Gennifer
Flowers a position . .. as First Bimbo.
Bill and Hillary's daughter, Chelsea, is
back at school. Her principal said she will

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be treated "just like any other student" ...
ow that the Church of England is
yeah, any student who has the bomb squad allowing female priests, l guess it's only a
matter of time before we start seeing male
opening her Cheese Doodles!
AI Gore will supposedly have a more nuns at the airport.
active role than he did at their first press
And, of course, baseball player Steve
conference where he looked like a cadaver Howe, who was thrown out ofbaseball18
on line at the ATM machine.
times for using drugs, just signed with
the Yankees. A spokesman for the
We now have two women senaYankees said that despite his probtors from California.
they were introduced to the
Q~[~t\ !ems and difficulties, "gram for
senate floor, Senator Bob
gram" he's still one of the best
PackwoodlMMEDIpitchers in baseball.
ATELY
Seems like someone forgot to
tell Bill Clinton that he won the
election because he's still on
the campaign trail. Responding to the death of
Superman, he claimed it
could have been avoided if
Bush had implemented humane health care reform . The
election year brought some interesting issues to the ballot. ln Northern
California there was the controversial
"Doctor-Assisted Suicide" Bill and in
Southern California, the "Police-Assisted Suicide" Bill.
But most of all , we are probably going to face some kind of government-mandated health care reform , leaving a lot of doubt and
uncertainty in the medical community.
Many wish we could just run things
involveour way. In this spirit, I would like to leave
ment!
To get some relief from politics, last you with the Top 10 Current Movies- if
week l watched the Frank Sinatra and the AMA were in charge of Hollywood.
Michael jackson specials back-to-back. l
Malcolm XXY
soon realized that they actually do have a
In House Alone 2
lot in common - they both grab their
A Broviac Runs Through lL
crotches and are willing to have their
Beauty and the Plastic Surgeon
noses broken to further their careers!
Th e Last of the Meconiwm
Back home, I discovered that the City
Bram Stol?er's Dracula's lnservice
of San Francisco is now being sued by
on
Exchange Transfusions
Tampa Bay because they didn't get the
Of
Murine and Men
Giants. Several local law firms are going to
Informed Consenting Adults
donate $3 million worth of legal services,
A La Leche League of Their Own
which works out to about three hours of
Three Ninjas On Rounds
work.

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"For his many scholarly contributions in genetics in general and to medical genetics in particular and for his
many personal contributions through
generations and generations of geneticists, young physicians and others, we
honor today Victor A. McKusick with
the bestowing of the D.W. Harrington
Award. "
McKusick was founding president of
The Human Genome Organisation from
1988 to 1990 and a founding member of
the American Board of Medical Genetics.
"Through his writings, courses, conferences and his personal example through
his relentless activities, he has organized
and called attention to important genetic
disorders that result from alterations in
fundamental biological processes. He has
been a major contributor to making possible the more recent applications of powerful molecular genetic technique to the
human disorders," Erbe said.
Editor-in-chief of Medicine and founding editor of Genomics, McKusick talked
about the international effort to map and
sequence the human genome.
"Thegoalofthe human genome project
is to locate all of these genes, to identify
them and to discover upon which chromosome they are situated and where on
that chromosome, and to determine the
full sequence of nucleotides from one end
of genome to the other," McKusick
explained.
"There was an influential editorial in
Science in March of 1986 suggesting that
the way to solve the problems of cancer is
to complete the sequence of the human
genome," he said in regard to the significance of the study of the genome.
The ational Academy of Science
committee recommended that a special
project was warranted and that it should
have add-on funding so there would be
no "robbing of Peter to pay Paul." Estimates of funding necessary to complete
the project approximate $200 billion

The Human Genome Proiect:
unraveling its implications
VICTOR MCKUSICK DELIVERS HARRINGTON LECTURE

he ~ddcning gap bt.&gt;t~H.'etl Hhat ph_';si( ians
kno1-v h(nv to diagnose and H· hat thn

hnov~.

haw to tnat ""'ill he inten~ified b1r the luto""' ledg£ gleaned front tlu I Iuntan (,enome Ptoject.
ptedic ted 1enowned geneticist\ idot A. tvkKusic h.
~1.IJ.,

'&gt;c. D., cL~ he delhCJrd the 1992 I).\\.

Ilanington I ccttoe. "I he llunu.ut C1enonte PJV)CCt:

Bachgnntnd,

~tat us,

Ptosp£ cts and bnplic ations. ··
members , quickly and unanimously,
reached a decision to give the award today
to Victor A. McKusick."
Erbe, who is director of the Division of
Genetics at The Children's Hospital in
Buffalo, chairs the study group that reviews all grant applications for proposals
to study social and policy issues of the
Human Genome Project. The massive
project to codify the sequence of nucleotide bases that makes up the genes in
each of the 23 chromosome pairs in the
human body has allocated a generous 3
percent of its budget to fund the study of
the ethical, legal and social implications of
its results.
Erbe lauded McKusick by saying, "Dr.
McKusick is a name really synonymous
with clinical genetics and ... a major figure
in American medicine.

McKusick referred to subjecting D A
to study as the diagnostic biopsy of the
gene- an approach that will be increasingly used to identify specific neoplasms
and their dispositions. But the knowledge
that comes from this study raises "ethical
and social issues" such as privacy and
confidentiality that are being given a great
deal of attention, he said.
And although some may try to make
connections between the genome's "constitution" and issues such as criminality,
McKusick said many of these associations
will be "spurious."
Richard Erbe M.D., UB professor of
pediatrics and medicine and chair of the
Harrington Lecture selection committee,
introduced McKusick, saying that although few geneticists have been chosen
for the Harrington award, "the committee

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(m 1988 dollars).

I

Also codtfted ts a growing hst of dtseases

anatomy. He explained that while
three categories of
genetic disorders

~~-~t~r'
/,I

feet. The first of
these diseases,
McKusick related, was

Huntington's disease , which was
f
mapped on the short arm o Chro~'1.~~~.,
mosome 4 in 1983.
"This type of mapping is useful because once one knows where the gene is
on the chromosome, one can hope to
design a diagnostic test," McKusick explained.
Of the 2 million plus genes in the
human genome - 2,600 have been
mapped. The genes for diseases such as
cystic fibrosis , one form of Alzheimer's
and Duchenne muscular dystrophy have
been identified.
McKusick said genes express disease

·: ·
f&gt;

.

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A graduate of Tufts University and
johns Hopkins' School ofMedicine where
he received his M.D. in 1946, McKusick is
a professor of medical genetics at The
johns Hopkins University.
- s v c A R R 1E A . L 1a E R A N T E

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Dean Naughton receives
Distinguished Service
Award from Sickle Cell
Disease Association

School of Medicine and Biomedical Sciences, the School of Social Work and the
Institute for CBO Education and
Training.

ohn P. Naughton, M.D., vice president for clinical affairs and dean of
the School of Medicine and Biomedical Sciences received a Distinguished Service Award along with
the medical school from the iagara
Frontier Association for Sickle Cell Disease at its twenty-fifth Anniversary Dinner
held last September.
Naughton was cited for "his notable
contributions to,
and support of,
the agency's
unique
health service to promote and ensure the well-being of the sickle
cell affected and
at-risk populations
ofWestern New York from 1981 to 1992."
During that time, a ugh ton provided a
quality of material assistance that substantially contributed to the association's survival, according to the citation he received.
He was also lauded for his active involvement in the creation of the Sickle Cell
Center of Western ew York at The
Children's Hospital of Buffalo, as well as
his "always available advice and counsel
on programs and problems."
The University was cited for "its invaluable contributions to, and support of,
the agency's unique community service
work." Individual units of the University
that provided singular contributions were
also cited. They include: the Student
ational Medical Association, the Black
Student Union, the Equal Opportunity
Program, the Office of Urban Affairs, the

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........ . ................. . ........... . .. . ........

idly growing field of medical information
into its curriculum, according to John
aughton, M.D., vice president for clinical affairs and dean of the School of Medicine and Biomedical Sciences.
"Ira was a visionary - always looking
two decades ahead," Olmsted, his wife of
39 years, said. "With medical informatics
the wave of the future, this chair, one of
the first of its kind in the country, represents an appropriate tribute to him."
The use of medical informatics is not
far off for UB's teaching hospitals, which
are working with the medical school to
develop an Information Systems etwork
to link health care facilities and physicians
in Western ew York.
The network will provide a national
and international prototype for medical
education and health care delivery, according to Thomas A. Riemenschneider,
M.D. , chair of the Western ew York
Health Sciences Consortium Information
Systems Council and associate vice president for clinical affairs and associate dean
of the medical school.
"The new Information Systems Network will place Western ew York on the
cutting edge of this medical technology.
The Ross chair in Medical Informatics
adds significantly to that impetus," said
Dr. Riemenschneider.

Medical informatics chair
to be estabhshed with gift
in honor of Ira Ross
ne of the nation's first professorships in medical informatics has
been established at the School
ofMedicine and Biomedical Sciences through a $1.5 million
gift in honor of the late Ira G.
Ross by his widow Elizabeth Pierce
Olmsted Ross, M.D., '39. Olmsted is a
practicing ophthalmologist and UB clinical professor of ophthalmology. The endowed chair will be known as the Ira G.
and Elizabeth Olmsted Ross Chair in Medical Informatics.
Ross, a distinguished aeronautical engineer, former president of Cornell Aeronautical Laboratories (later known as
Calspan) and a dedicated Buffalo community leader, died january 3, 1991.
The chair in medical informatics will
help the medical school integrate the rap-

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Correction
Our sincerest apologies to Robert A.
Klocke, M.D., for printing a photograph of Francis Klocke, M.D., (instead of Robert) in an article about
the medical school's annual faculty
meeting in the Summer 1992 issue.
Robert Klocke, a professor of medicine and physiology and chief of the
pulmonary division, received the
Stockton Kimball Award for excellence in academic achievement.

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Lore honored for oncologic
surgery contributions

project progress reports, Fish received
the 1985 Outstanding Teacher Award
and the 1987 Francis
V. Hanavan Outstanding Teacher
Award from the
SchoolofHealth Related Professions.
In 1985 , 1987 and 1988 he received
the Faculty Recognition Award from the
University's physical therapy program.
Fish is a member of the American
Physical Therapy Association, a manuscript reviewer for Physical Therapy and
Physical Therapy Practice and a member of
the MedicaVProfessional Advisory Committee of the Visiting Nurses Association of
Western New York

ohn M. Lore , Jr. , M.D., professor
and former chair of the Department
of Otolaryngology, has received the
Presidential Award of the American
Society for Head and Neck Surgery,
for "his leadership in raising the
quality and measurement of fellowship
training in Head and eck Oncology ... "
He is also the recipient of a Special
Recognition Award from The Society of
Head and eck Surgeons for his "untiring
service as chairman
of the joint council
for approval of advanced training in
head and neck
oncologic surgery."
Lore, the author
of An Atlas of Head
and Nech Surgery, is
a senior member of the Commission on
Cancer and a fellow of the American College of Surgeons. He holds dual certification by the American Board of
Otolaryngology and the American Board
of Surgery.

Bissonette re-elected head
of UCPA of WNY board
aymond P. Bissonette, Ph.D. , associate professor of family medicine at UB, has been re-elected
president of the board of directors of the United Cerebral Palsy
Association ofWestern ew York.
Also re-elected to the board was
Kathryn A. Sawner as vice president, executive assistant in the Office of the President and G. Alan
Stull, dean ofHealth
Related Professions
at the University at
Buffalo.
The UCPA of
W Y volunteer
board of directors
governs the policies
and procedures of
the agency which provides a comprehensive range of services locally to 1,200
adults and children with disabilities.

Fish wUI head physical
therapy/exercise science
ale R. Fish, associate professor of
physical therapy and exercise science, has been named to a threeyear term as chair of the Department of Physical Therapy and
Exercise Science in the School of
Health Related Professions.
Fish has been a UB faculty member
since 1974. He is also a clinical assistant
professor in the Department of Anatomical Sciences.
Author or co-author of numerous abstracts, book chapters,journal articles and

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Roswell doctors named
11
best" cancer specio6sts
ive physicians from UB and Roswell
Park Cancer Institute were selected
as among the 419 "best cancer specialists in the United States" in a
survey conducted by Good Househeeping magazine. The results were
published in the magazine's October 1992
issue.
Over 350 department heads and section chiefs at 110 major hospitals and
comprehensive cancer centers nationwide
were asked to name doctors they considered "outstanding" in treating the most
prevalent cancers.
Cited by their peers were Roswell Park
surgeon and research associate professor
of surgery Harold Douglass, Jr. , M.D., for
gastrointestinal cancer; surgeon and clinical professor of surgery Constantine
Karakousis, M.D. , for melanoma; surgeon
and clinical professor of gynecology and
obstetrics M. Steven Piver, M.D. , for gynecologic cancer; medical oncologist/hematologist, chairman of Roswell's Department of Medicine and professor of medicine Clara D. Bloomfield, M.D. , for leukemia, and medical oncologist/hematologist
and professor of medicine Geoffrey P.
Herzig, M.D.

GYN and OB managers
nome local editor
oni Canazzi has been named editor
in chief of AMGO News - the
newsletter of the Association of
Managers of Gynecology and Obstetrics.
Canazzi is a senior staff assistant
in the Department of Gynecology
and Obstetrics at The Children's Hospital
of Buffalo.

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Q
Evans receives Distinguished
Medical Alumnus Award

cation that l got at the University at Buffalo
and that my father got."
He said he would have liked the award
to have been given to his late father, a
graduate of UB's medical school and professor of anesthesiology, whom he described as a "pioneer" who established the
first anesthesia training program in the
country.
After graduating from UB medical
school in 1943, Evans interned at Philadelphia University Hospitals, Philadelphia
and Goldwater Hospital in New York City.
He then served two tours of duty in the
U.S. Army- the first as a post-World War
11 public health officer in japan and the
second as chief of the Hepatitis Research
Center in Munich, Germany.
Evans was appointed deputy chief of
preventive medicine and consultant in
epidemiology to the Army Surgeon General after his discharge from the Army. In
1987, he received the john R. Seal Award
from the Society of Medical Consultants
to Armed Forces, that organization's highest tribute.
In 1977, Evans, who majored in English as an undergraduate at the University of Michigan, received the Best Book
award from the American Medical Writers
Association for his textbook Viral Infections of Humans. The book is currently in
its third printing.
Evans has published more than 200
articles in professional journals and spent
his 43-year career studying the relationship of viruses to cancer and other chronic
diseases, focusing his interests on infectious mononucleosis and the Epstein-Barr
virus.
About80 people attended the dinnerto
see Evans receive his award, a specially
designed crystal bison, from Donald
Copley M.D., president of the Medical
Alumni Association.

LAUDS HIS LATE FATHER IN ACCEPTING AWARD

lfredS. Evans M.D., '43, consultant to ASA's Manned Space
Program and an infectious diseases expert, received the School
of Medicine and Biomedical Sciences' 1992 Distinguished Medical Alumnus Award on September 24 at a
dinner in his honor at the Buffalo Club.
"I am very proud to be the recipient of
this distinguished award," Evans said.
"You have a very distinguished group of
medical alumni. I am happy to be among
them. I am happy to be a member who has
been trained by this fine medical school."

Evans,john Rodman Paul professor of
epidemiology at Yale University for 20
years, was professor and chair of the Department of Preventative Medicine at the
University ofWisconsin until he retired in
1988.
A fellow and past president of the
American College of Epidemiology and
past president of the American Epidemiology Society, Evans served as editor in
chief of the Yale journal of Biology and
Medicine for three years.
On accepting his award, Evans said, "I
appreciate very much the wonderful edu-

-

BY

CARRIE

A

.

LIBERANTE

Alfred S. Evans, M.D., '43, (center) receives the 1992 Distinguished Medical Alumnus Aword, a
specially designed crystal bison, from Donald P. Copley, M.D., '70 (left) and Dean John Naughton, M.D.

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Annual James Platt
White meeting held
he james Piau White Societyof the School ofMedicine and Biomedical Sciences held its seventh annual meeting October 23.
The event included a
talk by joseph Prezio,
Chairman of the Department of
uclear Medicine, on the introduction of the medical school's
new Positron Emission Tomography Center as well as a tour of
the facility and the new cyclotron.
A reception and dinner dance
were held later that evening at
The Saturn Club.
The event honors members of
the society, who make annual
contributions of $1,000 or more
to the medical school.
The membersofthejames Piau
White Society for 1992 are:
Dr. Kenneth Z. Altshuler
Dr. Richard Ament
Dr. WilliamS. Andaloro
Dr. jared S. Barlow
Dr. Horace L. Banaglia
Dr. Charles A. Bauda
Dr. Barry Benisch
Dr. Richard A. Berkson
Dr. Willard Bcrnhoft
Dr. Paul K. Birtch
Dr. Theodore S. Bistany
Dr. Dennis L. Bordan
Dr. Willard H. Boardman
Dr. Martin Brecher
Dr. Harold Brody
Dr. james B. Bronk
Dr. Robert L. Brown
Dr. Melvin M. Brothman
Dr. August A. Bruno
Dr. Elaine M. Bukowski
Dr. Thomas S. Bumbalo
Dr. William M. Burleigh
Dr. David W. Butsch
Ms. Janel F. Butsch
Dr. john L. Butsch
Mr. David N. Campbell
Dr. Nicholas j. Capuana
Dr. Ben Celniker
Dr. and Mrs. joseph A. Chazan
Dr. Michael E. Cohen
Dr. Donald P. Copley
Dr. Daniel E. Curtin
Dr. Edward Diao
Dr. PeterS. D'Arrigo
Dr. Richard Daffner
Dr. RogerS. Dayer
Dr. Alfred H. Dobrak
Dr. Stuart L. Dorfman
Dr. Sterling M. Doubrava

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Dr. Ronald I. Dozorctz
Dr. Patricia K. Duffner
Dr. Kenneth H. Eckhen
Dr. Robert Einhorn
Dr. and Mrs. George M. Ellis
Dr. Alfred S. Evans
Dr. john A. Feldenzer
Dr. Donald M. Fisher
Dr. jack C. Fisher
Dr. Eugene S. Flamm
Dr. Thomas F. Frawley
Dr. Richard Gacek
Dr. Man A. Gajewski
Dr. Penny A. Gardner
Dr. Robert A. G1anfagna
Dr. john W. Gibbs
Dr. Mala Gupta
Dr. Thomas Gunuso
Dr. Theodore R. Hall
Dr. Eugene Hanavan,jr.
Mr. Edward Hansen
Mrs. Edythe T. Harris
Dr. Re1d R. Heffner,jr.
Dr. Orvan W. Hess
Dr. Williamj. Hewell
Dr. joseph M. Hill
Dr. Annabel M. Irons
Dr. Stephen joyce
Dr. james R. Kanski,jr.
Dr. john P. Kelly
Dr. Richard j. Ken line
Dr. Kenneth Kim
Dr. Hans F. Kipping
Dr. Arthur C. Klein
Mrs. jean L. Klein
Dr. Monon P. Klein
Dr. jacobS. Kriteman
Dr. joseph L. Kunz
Dr. Marvin Z. Kurian
Dr. Gordon R. Lang
Dr. Andre Lascari
Dr. Eugene V. Leslie
Dr. Lawrence M. Lesser
Dr. Harold Levy
Dr. Stanley B. Lewin
Dr. jack Lippes
Dr. Hing-Har Lo
Dr. Gary H. Lyman
Mrs. GraceS. Mabie
Dr. Michael M. Madden
Dr. Milford C. Maloney
Dr. Boris L. Marmolya
Dr. Don L. Maunz
Dr. Robert C. McCormick
Dr. Harry Metcalf
Dr. Merrill L. M1ller
Dr. Eugene R. Mindcll
Dr. joseph F. Monte
Dr. john D. Mounlam
Dr. Arthur W. Mruczek, Sr.
Dr. Richard L. Munk
Dr. Richard j. Nagel
Dr. Masao akandari
Dr. Richard B. Narins
Dr. and Mrs. john a ugh ton
Dr. Robert ey
Dr. john D. orlund
Dr. Timolh)' T. Nostrant
Dr. Ralph M. Obler
Dr. Benpmin E. Obletz
Dr. john j. O'Connor
Dr. Thomas P. O'Connor
Dr. Yasuyo Ohta
Dr. Carrie P. Ogorek
Dr. Elizabeth P. Olmsted

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[!]

Mrs. Rose Marie L. Wong
Dr. john Wright
Dr. HaJIIlla Yamabarashi
Dr. Gregory [. Young
Dr. Wende W. Young
Dr. Syedc r. Zafar
Dr. franklin Zeplowuz
Dr. and Mr;. David C. Z1egler

Dr. Dean E. Orman
Dr. johnS. Parker
Dr. Gerald E. Pancrson
Dr. and Mrs. Robenj. Pallcrson
Dr. Clayton A. Primer
Dr. Victor L. Pellicano
Dr. james F. Phillips
Mr. R. Willis Post
Dr. Linda Rabinowitz
Dr. Ben Rappole
Dr. Alben C. Rekate
Dr. Frank T. RiforgialO
Dr. Charles Riggio
Dr. Richard R. Romanowski
Dr. Charles Rosenberg
Dr. Alben G. Rowe
Dr. Eric j. Russell
Miss Thelma Sanes
Dr. DavidS. Schreiber
Dr. joseph I. Schultz
Dr. Roy E. Seibel
Dr. Elizabeth Serrage
Dr. Arthur j. Schaefer
Dr. Robert N. Schnitzler
Dr. Edward Shanbrom
Dr. john B. Sheffer
Miss Alice Simpson
Dr. john [. Spoor
Dr. William C. Sternfeld
Dr. Eugene M. Sullivan, Jr.
Dr. Michael A. Sulivan
Dr. MichaelS. Taxier
Dr. Charles S. Tirone
Dr. Edward A. Toriello
Dr. Anthony C. Trippi
Mrs. johnnie Vinson
Mrs. Yvelle Vinson
Dr. john P. Visco
Dr. Barbara Von Schmidt
Dr. Franklin Waters
Dr. Harold j. Weinstein
Dr. Virginia Weldon
Dr. Philip B. Wels
Dr. and Mrs. llarold F. Wherley
Dr. james j. While, j r.
Dr. Gary j. Wilcox
Dr. james S. Williams
Dr. Richard G. Williams

a

. . .

1993 Spring

Clinical Day and
Reunion
Weekend Set
Mark your calendars and
make plans to attend the
56th Annual Spring Clinical Day and Reunion
Weekend. The program
features cocktai I receptions
for reunion classes on Friday, Apri130, and james S.
Todd, M.D., executive vice
president of theAMA, speaking on "The ame of the
Game," and Reunion Dinners on Saturday, May l.

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�[!!·····························
Brown pub6shes history
of area medicine
rom the natural medicine of the
native Americans to the hightech practices of 20th centu!}'_
surgeons, KentL. Brown, M.D.y
'42 , has chronicled the extensive history of medicine in the
Westfield, ew York area.
His recently released book , A Medical History of Westfield, New Yorh, not
only recounts the history of nearly
100 doctors who practiced medicine
in the area , but captures the striking
evolution in the art of caring for the
sick over the last two centuries.
Brown's history , illustrated with the
drawings of jane E. Nelson, is a record of
those who tended the ill from the early
1800s when the Westfield area - then
called Cross Roads - was first settled.
The history begins with Westfield's
first physicians and continues to the
present. The
book features an
ex tensive

on the Civil War brings to life the
{). horror of that conflict.
Not only has Brown captured
the history of medicine in the
Westfield area, but his chapters
on what he believes was the first
autopsy in Westfield, Prohibition
Days, the !lu pandemic, the Lydia
Warner atrocity and many other topics
offer a unique microcosmic look at the
growth of the medical profession in
America.
Brown practiced medicine for
38 years in Cleveland before retiring to
his native Westfield. An assistant clinical professor of surgery at Case Western
Reserve University Medical School, he
has written and lectured extensively on
medical-legal problems. He is the author
of Medical Problems and the Law and The
Medical Witness , as well as several scientific papers.

subject index to help readers pinpoint
specific people and topics.
A detailed chapter on the remedies and
practices of the native Americans includes
a fascinating discussion on natural cures.
Brown also includes intriguing chapters on root and herb doctors and
homeopaths. A chapter

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~

Brown's Medical History of Westfield, New York is illustrated with the drawings of Jane E. Nelson.

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�································· · ······························································[ ! ]

Phrnp B. Wels, M.D. '41,
named chair of UB CouncH
hilip B. Wels, M.D., '41, has been
appointed chair of the University
at Buffalo Council by Governor
Mario M. Cuomo.
Wels, a clinical professor of
surgery at UB and distinguished
alumnus, has served on the council since
1980 and last year was named its vice
chairman. He succeeds M. Robert Koren,
who was chairman from 1981 until his
death last March.
"Dr. Wels has been a part of our university community for more than half a century. He knows UB inside and out, and has
a great deal of insight into the university's
relationship with the Western ew York
community," said B President William
R. Greiner.
Wels holds a bachelor's, master's and
medical degree from UB.
A founder of UB's fencing team , Wels
was a member of the United States Olympic fencing team in 1936 and served as
coach of the UB team from 1938 to 1940.
He was a member of the UB Athletic
Council and an original inductee into the
UB Athletic Hall of Fame in 1965.
He received the Distinguished Alumnus Award in 1979 and the Samuel P.
Capen Award in 1981. A trustee of the
University from 1972to 1976, he has been
a trustee emeritus since 1979.

Wels, a founder of the UB fendng team and its coach from 1938 to 1940, was a member of the U.S.
Olympic fencing team in 1936.
ciated with Hospice Buffalo - and the
hospice concept- since its inception in
Buffalo in the mid-1970s. Acting as its
first medical director on a voluntary basis,
Milch was pan of the group of health care
and commLtnity leaders that first introduced the concept to the area and focused
the attention of an international American
Cancer Society conference held here on it.
Milch also worked to educate health care
professionals as well as the community at
large about the benefits of hospice to both
patients and their families.
Milch served as medical director of the
Palliative Care
Unit at Buffalo
General Hospital, and has been
a staunch advocate for Hospice
Buffalo. On the
national level ,
he has acted as
co-founder of

Milch appointed full-time
medical director of
Hospice Buffalo
oben A. Milch , M.D., '68, has
joined the medical staff of Hospice Buffalo as its full-time medical director.
Milch , a clinical assistant professor of surgery, has been asso-

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Children's Hospice International and is a
member of that organization's scientific
advisory board. In 1988, he was given the
prestigious British Ambassador's Award
for his service to dying children and their
families.

Medical Alumni
Association estab&amp;shes
Achievement Awards
he Medical Alumni Association announces the creation of Alumni
Achievement Awards to honorthose
physicians who have demonstrated
uncommon dedication in research,
teaching, technical innovation, private practice, community ervice and
school administration.
The newly created awards will be presented annually at the Spring Clinical Day
luncheon .

e

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b::J
division of laparoscopic surgery,

a
retired psychiatrist writes, "In
three international photo salons
sponsored by the Photographic
Society of America, my stereo
slides won awards. Because most
of my photographs are close-ups,
I do not use a stereo camera; I use
two 35mm single lens reflex cameras whose shutters are synchronized electronically. The electronic flash units that I use are
also synchronized at speeds up to
1/50,000 of a second. lam over80
years old, so l find it easier to set
up my photo equipment on our
backyard patio than to travel to
some out-of-the-way place to get
unusual pictures. At present,
l have a Diamond Star in PSA
Competitions.
owl am accumulating credits for the
next PSA Stereo Division
Award, Master Stereographer l."

further development of the resi-

BERNARD S . STELL '36 ,

ARTHUR J . SCHAE FER '47 ,

was a member of the faculty for

dency training programs and enhancement of research activities.
He is an avid sailor and serves as
the Fleet Surgeon of the
Knickerbocker Yacht Club in Port
Washington, New York.

ELLIOTT BRENDER '70 ,
~ 11.

Elliott Brender '70

American College of Surgeons.
sor of surgery at the University of

retired from active family prac-

California at Irvine and chief of

tice. He has been promoted to

surgery at Garden Grove Hospi-

clinical assistant professor at the

ROY M . OSWAKS '71 ,

lege of Medicine and Dentistry.

cal College of Hampton Roads.

of

KENNETH P . SUN '89 ,

informs us that he and his wife are

Insurance

expecting their fifth child. He is

pital Center,

Company

DONALD SCH ERTZMAN '82 ,

and

lntracorp.

vania, had his fourth textbook,

Clinical Radiology: The Essentials,
published byWilliams&amp;:Wilkins,
ovember 1992.

minutes south of jerusalem, Israel on a West Bank settlement.

BURTON L. HERZ '67 ,

died May 9, 1987.

lem.

JOHN K . CU S ICK '57 ,

Schertzman's address is:
orthern

judean Desert, Israel.
com-

pleted three years in adult psy-

been appointed Director of Sur-

chiatry at Massachusetts General.

gery at New Rochelle Hospital

He is currently finishing a two-

Medical Center. Herz is respon-

chiatry at Massachusetts General.

administration of the department

5

His wife is at 5080

Lemon Bay Drive, Venice, Florida
34293.
ER IC ARNOU '91 , died

in Ari-

automobile accident.

ued growth and expansion of the

h

children.

zona on November 5, 1992, in an

of surgery, including the contin-

p

Talbott Recovery Center. He is
survived by his wife Pat and six

year fellowship in children's psy-

sible for the overall direction and

a

died

August 27, 1992. Prior to his
death he spent six months at the

ROY J . BOORADY '87 ,

has

RAY MONDW. M ITCH ELL'44 ,

He practices anesthesiology at
Bikur Cholim Hospital, jerusaMaalie Amos #109,

ptosis and acquired involutional

a

ew York.

practicing family medicine 30

in September. Schaefer lectured

B

is

currently an anesthesiology resident at St. Luke's Roosevelt Hos-

Hospital in Lexington, Kentucky

Association.

is currently a pediat-

for Health Care Compare and the
Southwestern Division of Cigna

a professor of radiologic sciences
at the Medical College of Pennsyl-

Minnesota, has been elected treasurer of the Minnesota Medical

LYN '88 ,

ton, Texas.

come the orthopaedic consultant

presented by the Center for Advanced Eye Surgery at Humana

ERI C K REE S E R '56 , ofBagley,

M ICHELLE V . ANDERSON -

rics emergency fellow in Hous-

ew Mexico, has be-

RICHARD H . DAFFNER '67 ,

ptosis."

jor 'project.'"

appointed assistant professor of

the Sixth Biannual Multispecialty

for the correction of congenital

was

clinical surgery at the Eastern Virginia Medical School of the Medi-

Oculoplastic Surgery Symposium

on "Levator aponeurotic surgery

writes, "I am continuing as an
urgent care physician in Miller
now two-years-old and is my ma-

ew jersey Col-

BERT A. LIES JR . '64 ,

T I NA MARIE GARDNER '87 ,

Place, New York. My son jake is

tal.

Robert Wood johnson School of

Santa Fe,

Roy J. Boorady '87

He is an assistant clinical profes-

BERNARD H . SKLAR '56,

Medicine of the

re-

cently became a fellow of the

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��BUFFALO PHYSICIAN
STATE UNIVERSITY OF NEW YORK AT BUFFALO

3435 MAIN STREET
BUFFALO NEW YORK 14214

ADDRESS CORRECTION REQUESTED

Non-Profit Org.
U.S. Postage
PAID
Buffalo, NY
Permit No. 311

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                    <text>State University of New York at Buffalo School of Medicine and Biomedical Sciences, Spring 1993

.

'•

B~~a~·se of it,
7,367 .Americans
will die this year.

�Dear Alumni and Supporters of the UB Medical School,

BUFFALO PHYSICIAN

\ olume

~7

1\ -be-

T

DIRECTOR OF
PUBLICATIONS (ACTING!
)- C m 'e ~m1th Pet o

he facultv of the Department of Social and PreYentn·e \ledKme and Gynecolog) and

Obstetri~s are pursuing the possihilit\· of bemg designated a \'anguard Center for the

EDITOR

-..anette Tramo;- r_,

g, R

ART DIRECTOR

\!an ] Kegler
ASSOCIATE ART DIRECTOR

Soa R f rich.
STATE UNIVERSITY OF
NEW YORK AT BUFFALO
SCHOOL OF MEDICINE
AND BIOMEDICAL
SCIENCES
1
John "\~mg',~ );--. \ L ~: Prcslc ~nt
fc r Climcal -\ffz s, D.· Jlt

EDITORIAL BOARD
)r )0hn \ Rich t C

r• ..,.." •

Wvmen s Health Initiati,·e Clinical Trial sponsored b' the :\atioroal Institutes of
Health.
This m1tiat1Ye ''as approYed by Congress and is designed to eYaluate the health status
vf women and the effect of a selected number of interYentions important to the health of
women. Dr. \laurizio Tre\isan and Dr. \lyrosla\\ Hreshchyshyn
haw proYided excellent leadership for this important multidisciplinaf\
effort TwentY-four organi::ations are being site-Yisited and it is
expected that 15 wtll recciYe the designation of a Vanguard Center
UB 1s wn excited about th1s possibdn' because clinical trials arc an
important component of our research portfoho, and thts trial in
particular, serws to complement our other inil!al!Yes re:.ned to
pnman health care, health promotion and d1sease preHntion The
staff of the Buffalo Physic tan and 1
keep you abreast of our
progress in this Important area

''ill

Sincere!~,

~~- R charc de Asia
Dr \lo t - r ec ·or
!.)r HOl old Bn""~d\
D• R charL Lolhns
!), Donald P (.&gt;:&gt;lev
'"lr I !an J Dnnnan
L&gt;1 fi -"'C'l \ ual-rvc

Dr Glen ( res',J-,
]a -es Kd. 1s"'i

john ;'&gt;.aughton, ~!.D.
\'ice Prcstdcnt for Cli111cal 4.ffairs
Dean, Sdwol of \fcdiCIIIL cwd Bio111cdical Sciences

L)r

harles \lassar ..l
( harles Poganelh
L utrc Rc bnson
T cmas Rcse ·hal
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Bra&lt;llrv
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s, phen Snaul&lt;ung
jerome\ •• .:s

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Dr
Dr

Dear Fellow Alumni,

TEACHING HOSPITALS AND
LIAISONS

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\ddr&gt;ss &lt;JU stions, wmments and
submis'i&lt;.."- ~ ~o
F c! tor b.IJJ.l'~
Pin s.(.UHl State l nivercoih of t\,;.c''

' ' k Jt BuffJIJ
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Send address changes to:

BuJ ,•
PII) '" an 14f ( FS \J&lt;.htwn. l h
\1ain~t eet Puffalo,"'cw\or' 1+21+

Cover llluslrolion by Ted Pitts

T

he excitement mounts as we approach the focal pomt of our -\lumni war- our 56th
annual Spring Clinical Day on \lay 1, 1993 at the Buffalo \Iamott. \\'e are expLcting
~arucularly good att.endance this ,·ear for our C\-cle of class reumons going back o\'er
)0 years. As) ou h.n e come to expect, we w11l also be presentmg another proYocatl\ e
and challengmg cducauonal program that this Year is entitled "Doctor Watchers." This
program will highlight the Yarious agencies that monitor physiuan performance and
suggest \\a\·s to aYoid unwarranted scrutin). Our energetic ch:urpcrson, Dr. \largaret Paroski, has obtained commitments from an
outstanding group of knowledgeable speakers. From Rochester
comes Dr. Charles\ acanti, who is presentlY ser\'lng as Chairman of
the '\Je\\ York State Board of Professwnal Conduct. Another speaker
wlll be '\Janq ' iclsen, \\ell-known Buffalo internist and currenth the
Regional ~led !Cal Coordinator of the Office of Professional Conduct.
Other local speakers will include Dr Ross Hewitt from the AIDS
ser\'lce at Erie Count\ \ledical Center and Dr. \lichael Horan clinical
mstructor in pediatrics at The Children's Hospital of Buffalo Our
d,stinguished Stockton Kimball lecturer thisyearwill he the American Medical -\ssociation's
Dr James Todd, talking about "The '-Jame of the Gaml" As alwaYs, thts program carries
four hours of Category 1 C\IE credit.
Be sure to look a gam this year at the full Yaricty of Spring Clinical Day poster displavs
summari::ing much of the current medical research being done at the UniYersity. \\ e are
also Yen· pleased this year to be presentmg for the first time a group of Alumm
Achie\·ement Awards at the afternoon luncheon honoring alumni who haYe made
outstandmg contnbutions in partJCular fields of medical endeaYor or communit) sCf\"lce
And don't forget our popular fridav night reception April 30th at the Center 'or Tomorrow
thM th1s year wdl recognize our Reunion Chamnen as thev present for the first time our
\lumni Scholarship awards to desen·ing medical students. This Year"s Spring Clinical Da\
\\ill certain I) be memorable and I urge you all to attend.
'I ours truh,

Don Caple). \I D .. '70

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IJ Research
IJ Hospital News
II Cluster lllnessese

UB med student wins American Public
Health Association award. Page 22.

Sorting through one
of the most vexing
phenomena in medicine.

m

The Waiting Game e Despite advances in transplant
technology, one-fourth of the people waiting for
organs will die because of a shortage of donors.

Leaving them laughing using humor in talks and
presentations. Page 25.

m

Medical School

ASpoonful of Humor
, Alumni
Classnotes

~tanoaro

antibiotic
therap~ for ear
infections calleo
ineffectiue.
rage ~.
New Roswell Park testing helps ensure
safety of donated tissue. Page 20.

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girls, he points out, and bottle feeding blood flow, " said Alan Lockwood, M.D.,
appears to be associated with increased UB professor of neurology and nuclear
medicine and director of PET operaotitis media with effusion.
In addition, the earlier in life children tions at the Buffalo VA. "This will
octors know that ear infections in develop ear infections, the greater their expand the capability for existing and
children rise as the temperature falls. risk of suffering recurring infections future PET system," he added.
+
But what they don't know, says a UB throughout childhood. Other factors such
researcher and physician, is how to as family history, allergic conditions and a
effectively treat the condition, de- mother's cigarette smoking might increase
spite decades of antibiotic use.
the risk of otitis media.
'The very fact that otitis media ... in the
The standard treatment for ear infecantibiotic era, has emerged as a disease of tions is successive doses of antibiotics, an
overwhelming, epidemiologic importance, approach that has resulted in increasing
he National Cancer Institute has
awarded five multi-year grants totalmust indicate that the treatment of this populations of resistant bacteria, Bernstein
ling$1,566,723, to UB-Roswell Park
condition has been somewhat of a fail- notes.
+
BY
LOIS
BAKER
Cancer Institute researchers.
ure," saidjoel M. Bernstein, M.D., clinical
Richard Bankert, an associate reassistant professor of otolaryngology and
search
professor from Roswell's depediatrics.
Otitis media accounts for more pediatpartment of molecular immunology, received a fourric visits to doctors' offices than any other
year, $572,764
infectious disease and is the most common cause of hearing loss in children,
grant to assess
he Buffalo VA Medical Center will Epstein-Barr ViBernstein writes in Hospital Formulary.
receive more than $I50,000 to de- rus (EBV) vacciSome children have ear infections more
velop software for its new Positron nation strategies
than others- a result, he says, of characEmission
Tomography (PET) scan- to determine their
teristics or conditions that seem to predisner through a grant developed un- ability to induce
pose certain children to the condition.
der a cooperative research and de- immunity in laboBoys tend to be more susceptible than
velopment agreement
ratory mice from
between the VA and SieEBV-induced disseminated lymphopromens Medical Systems.
liferation.
The three-year reBonnie B. Asch, Ph.D., an assistant research project, formed
search professor from Roswell's experiunder the auspices of the
mental pathology department, received a
four-year, $421,795 grant to investigate
federal Technology
Transfer Act, will allow
mammary cell markers in different stages
the development of two
of progression to malignancy.
Carleton C. Stewart, Ph.D., a UB renew software modulesone to compute blood search assistant professor, received a fourflow and one to describe year, $239,499 grant to conduct a multiparameter flow cytometric analysis of
metabolism in the brain
solid tumors. Stewart, from Roswell's flow
using mathematical
cytometry facility, also received a threemodeling of biochemiyear, $158,574 grant to study the role of
cal reactions.
flow cytometryin molecularphenotyping.
"Right now there is
Thomas S. Mang, Ph.D., a research assono software in our computer system that enciate professor from Roswell's radiation
ables a user to measure medicine department, received a three-

Standard antibiotic treatment for
ear infections labeled ineiTective

NCI awards $1.5 million in grant
money to UB-Roswell researchers

VAMC receives cooperative grant
to develop new PET software

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women and 239 Italian
women with relation to
16 symptoms during
three phases- premenstrual (defined as the week
before menstruation),
menstrual and the
remainder.
Results showed that
omen from different cultures, livAmerican and Italian
ing vastly different lives, experiwomen experienced
ence many of the same menstrual
nearly the same amount
and premenstrual symptoms, a
of symptoms overall,
State University of New York at
while Bahrainian women
Buffalo researcher has found.
reported fewer symptoms.
The study is the first large-scale, popuWomen's experiences
lation-based comparison of menstrual
across cultures were most
cycle distress across cultures.
similar during the men"Margaret Mead suggested cramps are
strual phase, and least
trans-cultural symptoms," said Lisa A.
similar during the remainder phase.
Monagle, Ph.D., clinical assistant profesSymptoms reported during the premensor of social and preventive medicine and
strual phase were revealing, Monaglesaid,
lead investigator in the research. "Our
because they show that the condition
study confirms this, and also suggests that
known as premenstrual syndrome (PMS)
other symptoms, such as water retention,
is not, as some people have suggested, a
emotional distress and decreased activity,
media-created phenomenon. Premenare experienced trans-culturally as well."
strual symptoms common to all three
The study compares the experiences of
cultures were fatigue, anxiety and cramps.
179 American women, 172 Bahrainian
Generally, Monagle found as many differences as similarities between cultures
in the prevalence ofindividualsymptoms,
but found consistent symptom groups
+
across all three cultures.

.

' .

year, $174,091 grant to investigate the use
of photodynamic therapy in the treatment
of pancreatic cancer.
+

Menstrual symptoms experienced
across cultures,UB study shows

BY

LOIS

BAKER

Tacrine found to reduce some
early Alzheimer'ssymptoms
UB researcher is one of six authors
of a study published in the ovember 11, 1992 issue of the journal of
theAmericanMedicalAssociation that
shows the drug tacrine is effective in
reducing some of the symptoms of
early Alzheimer's disease.
Linda A. Hershey, M.D., associate pro-

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fessor of neurology and chiefof the Buffalo
VA's neurology service, performed the
study at the Buffalo VA Medical Center
with Kerry Donnelly, Ph.D., assistant professor of psychology, and Karen Burch,
R.N., clinical nurse specialist.
The 20 patients in the Buffalo component of the study were among 468
Alzheimer's patients at 23 outpatient centers nationwide enrolled in the trial.
The study involved men and women
over 50 who were mildly to moderately
impaired due to probable Alzheimer's disease, but otherwise in good health. During the 12-week trial, patients received
either a placebo or a daily dose of tacrine.
Tacrine-treated patients showed significantly more improvement in memory and
language than those receiving a placebo.
Physicians and caregivers also noted
greater improvement in behavior in the
tacrine-treated patients than those on placebo. Patients taking tacrine should be
closely monitored for side effects, including liver toxicity, nausea and vomiting,
diarrhea, abdominal pain, dyspepsia and
rash, Hershey cautioned.
+
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Deaconess establishes area'sfirst
pediatrtc long-term care unit

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couraged to participate in formulating care
plans, as appropriate.
The 21 pediatric S F beds are being
filledinstages,withoccupancyofthefirst
two-thirds already completed and the last
third anticipated by June.
Jan Valencourt, R. ., is the unit coordinator.
+

he only long-term pediatric care
unlt m upstate ew York opened
late last year at The Deaconess Center, a division of The Buffalo General Hospital.
The 21-bed unit will
care for children with congenital defects, specialized medical
problems and head trauma. It is
the seventh such facility in ew
York State.
The pediatric unit is the final
link in an $8 million renovation
and construction project at Deaconess that began in 1989. An
earlierphaseoftheprojectadded
38 geriatric beds to the facility,
which now has 200 geriatric
skilled nursing beds, 21 adult
long-term care head trauma beds
and the pediatric unit.
"A serious shortage of skilled
nursing beds for children in the
state prompted Buffalo General
to develop this specialized unit,"
said Marilyn ]. Gibbin, BGH
vice president for long-term
care. "Because of this scarcity,
we anticipate referrals from local agencies, as well as downstate and out-ofstate," she added.
Gibbin noted that The Children's Hospital of Buffalo served as an early catalyst
for the project and trained the unit's nursing staff. Linda A. Kam, M.D., medical
director for the new unit, has privileges at
both hospitals.
In addition to physicians and nurses,
the unit's multidisciplinary team includes
social workers, audiologists, leisure time
activities and educational personnel, nutritional services staff and occupational,
speech and respiratory therapists. Families, and the children themselves, are en-

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sliding glass door to allow for both continuousobservationandquietprivacywhen
desired. Each patient room also has a large
window to allow for ample natural
lighting."
The new ICU connects directly to Sisters' new surgical unit, slated to open in
March. A new on-call physician room
adjacent to the unit has also
been added.
The renovated units feature
time-elapse clocks in patient
rooms and nursing stations to
facilitate code and drug administration record-keeping, air
mattresses with pumps, scales
mounted directly onto the beds
and hemodialysis hookups at
each bed.
+

Edge appointed chief of
Roswell Park breast
surgery division
tephen B. Edge, M.D., has
been appointed head of
the Division of Breast Surgery, Department of Surgica I Oncology, at Roswell
Park Cancer Institute.
Before assuming his position at Roswell
last summer, Edge served as assistant professor of surgery at the University of Virginia at Charlottesville since 1986. He is
a graduate of Case Western Reserve University Medical School and completed his
internship and residency in general surgery at the University Hospitals of Cleveland. He served a threeyear fellowship in surgicaloncologyatthe ationa! Cancer Institute,
Surgery Branch.
Edge is a principal investigator with the a-

Sisters of Chanty Hospital opens
renovated critical care units
s part of its $42 million renovation
project, Sisters Hospital has opened
its newly modernized 16-bed intensive care and eight-bed coronary
care units.
"Both new critical care units offer
patients and staff a much larger area," said
Sister Mary Kelley, vice president for asset
management. " ursing observation stations with recessed lighting and large
counter areas overlook generous patient
care rooms. Each patient room has a

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A topographic corneal scan, showing (at right) an essentially normal eye with mild astigmatism and (at
left) an eye with keratoconus (pre-corneal transplant).

assigned to a certain power range to produce a color-coded contour map of the
cornea.
One of the main diagnostic advantages
of the new analyzer, Reidy said, is its
ability to confirm the presence of certain
conditions that previously could only be
speculated, such as early corneal abnormalities.
Special software added to the $30,000
analyzer allows operators to produce computerized spheric or aspheric contact lens
fittings for difficult-to-fit patients. Millard's
Eye Department, which has been doing
five to 10 exams a week since it obtained
the analyzer about a year ago, takes referrals from eye care professionals throughout Western New York, Reidy added. +

illard Fillmore Hospitals' Gates
Circle facility has become the only
facility in Western New York to
offer topographic corneal scans
using newly developed computerized technology.
The hospital's corneal analyzer uses
concentric rings of light focused on the
cornea to map its shape. Used to determine the presence of certain corneal conditions such as keratoconus, astigmatism
and post-corneal transplant torsion, as
well as for contact lens fittings and preradial keratotomy mapping, the analyzer
uses video technology to capture the rings
of light reflected off the cornea and then
digitizes the image to produce a full-color
print out, according to James]. Reidy,
M.D. , assistant professor of ophthalmology and director of the cornea service at
Erie County Medical Center. A mathematical formula translates the distance
between the individual rings and transforms those distances into corneal power.
"The rings are traced by computer, as
well as each space between each of the 15
rings along 270 different meridians, and
translated into the corneal curvature,"
Reidy said. The results, he added, are

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Millard oiTers first topographic
corneal scans in WNY area

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tiona! Surgical Adjuvant Breast and Bowel
Project- a group of cancer researchers
that receives support from the ational
Cancer Institute. A leader in breast cancer
research, the group was a dominant force
behind the widespread use of less extensive surgical procedures for breast cancer.
A fellow of the American College of
Surgeons, Edge is also a member of the
American Society of Clinical Oncology,
the American Federation of Clinical Research and the Southeastern Surgical
Congress.
+

-

B Y

N ANETTE

T RAMONT

KOLLIG

Buffalo General Hospital names
new head of orthopaedic surgery
enneth A. Krackow, M.D. , an
orthopaedic surgeon who specializes in hip and knee replacements,
has been named head of the Department of Orthopaedic Surgery
at The Buffalo General Hospital.
Krackow, also named professor of
orthopaedic surgery at the University at
Buffalo, succeeds Edward H. Simmons,

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M.D. , who had served as head of BGH's
orthopaedic surgery department since
1983 before retiring from the position late
last year. He remains an active member of
the orthopaedic surgery staff.
Immediately prior to accepting his new
position at BGH, Krackow was a professor, full-time faculty, Department of
Orthopaedic Surgery at
Johns Hopkins University Medical School.
He was also a member of the active
orthopaedic surgery
staff at Good Samaritan
Hospital, Children's
Hospital and Union Memorial Hospital,
all in Baltimore.
Krackow has authored numerous journal articles for peer and non-peer review
publications, written four books and chapters for many others. His 1990 book, The
Technique of Total Knee Arthroplasty, is
used by most of the nation's orthopaedic
surgery residents.
A member of the American Orthopaedic
Association, he is also a diplomate of the
ational Board of Medical Examiners, a
member of the American Academy of
Orthopaedic Surgery, the Orthopaedic
Research Society, the Knee Society and the
American Medical Association. He is board
certified by the American Board of
Orthopaedic Surgery.
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Since the childhood diabetes cases a
decade ago in Poland, researchers have
found other outbreaks, and the World
Health Organization now hopes that further study can identify environmental
agents at work in the disease.
But cluster investigations aren't easy,
and for every one that adds to medical
understanding, many, many more raise
unanswered questions, hit dead ends or
simply prove to be matters of coincidence.
"The cluster phenomenon is very difficult to evaluate," said Alfred S. Evans,
M.D. , a 1943 graduate of the UB medical
school, winner of the school's 1992 Distinguished Medical Alumnus Award and
Yale University professor emeritus of epidemiology.
In the UB incident, there were 15
Hodgkin's disease cases among 5,708 faculty, staff and students who once used a
building at 4230 Ridge lea Road in
Amherst. The New York State health department labeled it a true cluster, noting
that the cases occurred at more than four
times the national rate. But it also found
that the people with Hodgkin's had a
number of demographic and medical char-

ln midwest Poland, physicians notice
an upsurge in childhood diabetes so striking that it looks for all the world like a
communicable epidemic.
In a building once used by the University at Buffalo, worried faculty and staff
members tally the number of Hodgkin's
disease cases among their colleagues, then
call in the state Department of Health.
Clusters of chronic disease are among
the most vexing phenomena in medicine.
Communicable diseases are by definition
subject to outbreaks. But tumors? Multiple sclerosis? What is the small-town
pediatrician to make of the third patient
this month to be diagnosed with childhood leukemia?
Chronic disease clusters are rare, but
hardly unheard of. And in some cases,
they can yield significant medical insights.
After dogged field study, some good
hunches and a little luck, the strange jaw
tumors noticed in Africa by Denis P.
Burkitt, M.D. , in the late 1950s contributed not only to the discovery of the
Epstein-Barr virus, but also to theories on
relationships between the virus ,
immunodepression and cancer.

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acteristics closely associated with the disease. ln essence, investigators said the
cluster was one of risk factors and probably would have occurred if the same
group of people came together anywhere.
Unusual? Yes. Reason for alarm? o.
ot everyone is satisfied.
"I think it was kind of a pat on the head,
you know, 'Don't worry,"' said Joel S.
Rose, who once worked at 4 230 Ridge lea.
"I have colleagues who worked in that
building, and I'm concerned about their
welfare. "
The public in general has grown more
concerned about clusters in recent years.
Hardly a day goes by at many large public
health agencies without a call from someone who's noticed that there's an awful lot
of cancer in the neighborhood lately. Many
in public health think people have every
right to be concerned, and government
has been devoting more resources to cluster investigations. But physicians and
policymakersstillgrapple with how much
to spend in light of other needs.
"It's a very important question because
the past experience has been that they
(cluster investigations) tend to be

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�unrewarding," said Curtis Mettlin, Ph.D. ,
UB research associate professor and director of cancer control and epidemiology at
Roswell Park Cancer Institute in Buffalo.
"There have been very few instances where
a cluster aha lysis has led to disease prevention or control. More often they end up
unexplained. There are some cases historically, though, which turned out to be
so rewarding. "
Cluster investigations are nothing new
to medicine. In fact, since john Snow
noticed 139 years ago that a London cholera outbreak was concentrated suspiciouslyarounda public-water pump, clusters have been at the heart of epidemiology. And just as that case contributed to
the understanding of infectious disease,
researchers have long hoped cluster investigations could shed light on diseases like
cancer. As far back as the late 19th century
there was a cancer-cluster study in Buffalo; a map from it remains on display in
the Roswell Park library, Mettlin said.
Over the last two decades, cluster cases
have jumped from the medical journals to
newspapers and television. After the ational Cancer Institute showed with maps
in the 1970s that clusters were present in
the Northeast, the ew jersey Turnpike
would forever be known as "Cancer Alley." In 1978, the ew York State health
department found that people living next
to iagara Falls' Love Canal appeared to
be at heightened risk for miscarriages and
birth defects and sent panic through the
community when it recommended pregnant women and children under two years
leave the area directly adjacent to the site.
Residents subsequently did their own
health surveys, and under the glare of
network television lights successfully
pushed for evacuation of the wider neighborhood.
john E. Vena, Ph.D. , associate professor in the UB medical school's Department
of Social and Preventive Medicine, began
his epidemiological work at Love Canal.
"It made people aware that there are problems out there that aren't figments of their
imagination," he said.

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�cause, and the exposures are often high. In
neighborhoods, however, the number of
cases tends to be relatively small, people
move in and out and exposure levels are
much lower.
"We feel people do have a right to know
what's going on in their communities,"
said Philip C. asca, Ph.D. , director of the
New York State health department's Bureau of Cancer Epidemiology. "But I will
say this up front- it's very difficult with
these methodologies to pinpoint an exposure. "
With a five-decade-old cancer registry
and cluster investigation units dating to
the 1970s, New York is considered one of
the leaders in the field. But efforts have
been growing nationally.In 1989 the Centers for Disease Control and Prevention,
the Association of State and Territorial
Health Officials and the Agency for Toxic
Substances and Disease Registry held a
two-day conference on clusters. They followed up with a set of guidelines for health
agencies, published in the CDC's july 27,
1990, Morbidity and Mortality Weekly
Report supplement.
According to the guidelines, clusters
that might yield important findings share
several characteristics: "Usually such a
cluster has a definable health outcome,
either new or rare; a potential exposure or
agent is suspected, along with a connection between the exposure and the health
event; the situation is highly unusual, and
statistical testing confirms the investigator's
impression; and the short-term public
health impact is immediate and self-evident. "
Few clusters make the grade.
"More clusters are due to a chance
occurrence of rare events, what I've heard
some people call the 'expected unexpected,"' said Ward Cates, M.D., M.P.H. ,
director of training in the CDC's Epidemiology Program Office. "just by chance
alone, these things are going to occur."
Some initial cluster reports come from

Frequently it is related to the environment, or at least to where people live.
Many chronic diseases do follow geographic patterns. Multiple sclerosis is more
common in temperate climes. So is
Hodgkin's disease. But why? Is it something in the air? Better diagnosis and reporting of cases? Or something else?
Burkitt found that his jaw tumors occurred only below a certain altitude, later
realizing that temperature was the critical
factor. He also found correlations with
rainfall. Then someone suggested he compare his maps of tumor incidence with
maps of intense malaria cases.
Bingo.
Eventually Burkitt came to believe that
the Epstein-Barr virus, in the presence of
immunodepression brought on by longterm malaria, could cause "Burkitt's
lymphoma."
Today, the relatively frequent clustering of diseases like multiple sclerosis and
Hodgkin's have bolstered theories that
viral agents are at work there, too.
In many cluster cases, pollution is also
a suspect. Animal tests have linked anumber of chemicals to cancer. And some
studies have found a correlation between
high cancer rates and proximity to chemical plants, hazardous waste sites or ground
water contamination.
"There's no question that clusters could
occur with an appropriate exposure,"
Evans said.
Proving it is another matter.
To document an environmental connection to a cluster, he said investigators
should show a relationship between incidence and the duration of and proximity
to the suspected cause. They should also
study a large, comparable area that is free
of the suspected cause. All in all, he said,
it's a daunting task.
In occupational cases, particularly industrial ones, investigators can at least
document how long a person has worked
and been exposed to a suspected disease

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physicians, but the vast bulk are made by
the general public. In New York State last
year, the health department's Bureau of
Cancer Epidemiology received 328 phone
inquiries.
"We've always sworn that right around
Christmas time, when people get together
at parties, we tend to get a lot," said Nasca,
who earned his Ph.D. in epidemiology
from UB's Department of Social and Preventive Medicine.
Of the hundreds of cluster reports annually, asca said about three-quarters go
no further than the initial call. The department has an ombudsman to handle the
reports, many of which involve a variety of
cancers. After asking some questions, the
ombudsman is usually able to tell the
caller that there's nothing unusual going
on.
"Lay people have the idea that no matterwhat the disease is, it must all be caused
by the same thing," said Brix. "We have to
do health education and explain to people
that first of all, cancer is very common,
unfortunately. One-third of Americans will
get cancer at some point in their lives and
one-fourth will die of cancer."
If there does seem to be something
unusual, the department will check its
cancer registry, and that often resolves the
issue. For instance, asca said, a report of
four brain tumors on one block will raise
eyebrows, but on checking the registry
investigators may find that the tumors all
metastasized from different sites, greatly
reducing the likelihood of a true cluster.
If the registry confirms the report and sometimes it reveals even more cases
-the department calculates whether the
number of cases really are more than
would be expected. Nasca said investigators work with local citizens and health
officials to draw boundaries for the study
area, taking local concerns and scientific
needs into consideration.
"If it looks like nothing is going on, we
write up a long report as well as a simpler

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�executive summary," he said. The reports
go to local health officials and concerned
citizens.
When a study confirms there are more
cases that expected, investigators interview the patients, asking about medical
history as well as lifestyle, occupation and
where else they have lived.
In eight cases last year the department
went at least as far as checking whether the
observed cases were more than expected,
and as of early this yearthere were 19 other
such studies under way. "In some cases we
have confirmed some excess," asca said.
"The real problem is trying to confirm
some etiology."
Given that, resource allocation is one
of the biggest issues facing cluster investigators.
asca feels that as long as clusterinvestigation units carefully target their
studies and help educate the public in
cases that don't merit investigation, their
cost is well worth it. But he notes that the
state is also working on cancer research,
intervention and prevention. "I would not
want to see cluster investigations draw
staff from those other important areas," he
said.
+

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still remain

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relations aspects of their task as well as the and indicators of pre-existing immunological problems, also risk factors. And
scientific issues.
At Ridge Lea, things got off to a bad several had family members with
start. The investigation officially began in Hodgkin's. All were at risk for the disease
1989, but after two years little had hap- before ever setting foot in the building.
pened. Two people with Hodgkin's died
"We don't think there's anything in
without being interviewed by the health that building that would make it unfit for
department, Hastrup said. And people human occupancy," Brix said. "These
who had used the building were not alerted people had a very high prevalence ofknown
to seek early treatment if they had
risk factors associated with Hodgkin's disease. I'll be honest, I was surprised at how
Hodgkin's symptoms.
After a letter from 50 faculty, staff and well they fit the pattern. "
students and some pressure from the adHastrup doesn't buy it. 1f you had a
ministration, the health department as- group with an unusually high rate ofbreast
signed Brix to the case in 1991.
cancer, she asks, would you be satisfied
She documented 15 Hodgkin's cases simply to know that the victims were
among the 5,708 faculty, staff and stu- women? She said the cluster can't be exdents who used the building the most plained by risk factors without knowing
while it was part ofUB's temporary Amherst how common those factors were among
campus from 1969 to 1986. The incidence everyone who used 4230 Ridge Lea.
"I don't think the health department's
was more than four times the rate for the
nation as a whole and more than three explanation is sufficient," she said.
"What they're basically asking us to do
times the rate for upstate New York, where
Hodgkin's is more prevalent than it is is a 45-minute interview on over 5,000
people," responded Brix. "It's an enornationally.
The health department tested the build- mous use of state resources, and there's no
ing for chemicals, ionizing radiation and scientific reason for it whatsoever. "
Clifford B. Wilson, UB associate vice
magnetic fields. It found nothing unusual.
But, Brix said, she did find something president for student affairs, said he acunusual among the people with Hodgkin's. cepts Brix's conclusion. He said he would
They were of higher than average socio- rest easier if there were something more
economic status, which previous studies concrete than risk factors to explain the
have found to be common in people with cluster. But, he added, ''I'm not sure what
+
the disease. Many had had mononucleosis more one does. "

Overtheyears,janicel. Hastrup, Ph.D.,
sensed that something was wrong.
In talking with other UB faculty, staff
and students who used the temporary
building at 4230 Ridge Lea Road in
Amherst, Hastrup heard about four with
Hodgkin's disease. It seemed like a lot.
Then, in 1989, there were two more
cases. Hastrup, an associate professor of
psychology, called the ew York State
Department of Health.
Last summer the health department
confirmed that there indeed had been a
Hodgkin's disease cluster at 4230 Ridge
Lea. But it said the cluster had more to do
with the backgrounds of those who were
sick than with the building they shared.
UB accepts the findings. Hastrup and
several others who used the building don't.
"It's better to say you don't know than
to say you've explained it when you
haven't," she said.
"We did a very thorough investigation
both on the health side and the environmental side," countered Kelley Ann Brix,
M.D. , of the health department's Bureau of
Environmental and Occupational Epidemiology.
Cluster investigations frequently fail to
satisfy the people who requested them.
Cover-up charges are so common that
guidelines published by the Centers for
Disease Control and Prevention suggest
investigators be sensitive to the public

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It will be a
deadly one
for 7,3&amp;7 of
the 29,4&amp;9
Americans
waiting
for organ
transplants.

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�odern medicine has come a long
wa~ Docto~

but in this day of xe-

nograft transplants from baboons
and microscopic cookie cutters
for replacing human corneas) a
frustrating dichotomy exists.
Under its end-stage renal disease program, the federal government spends $3.5
billion a year to treat patients who could
be taken off dialysis if donor kidneys could
be found. And, the average ICU patient
awaiting a liver transplant runs up costs of
between $1 ,000 and $2,000 a day.
The donor shortage, according to kidney transplant surgeon Sidney Anthone,
M.D., needs to be addressed from both an
educational and a legislative point of view.
Anthone chairs an ad hoc committee for
the United etwork of Organ Sharing
(U OS) - made up of the country's 75
regional organ sharing centers and their
computer networks- which has among
its goals the integration of the organ
donation process into medical school
curriculums.
"Curriculums are crammed already,"
notes Anthone, professor of surgery at UB.
"But a curriculum has been written by
U OS for nurses, medical students and
neurosurgeons. It is now a matter of
putting it into the schools and promoting
it, having somebody who will go around
and stampede for it."
Indeed, the organ procurement movement needs a P.R. boost. It's a life-anddeath matter for the 22,415 Americans
who, as of]anuary 1993, were waiting for

Tremendous diagnostic, surgical and
treatment advances have brought organ
transplantation into a new era. But the
single biggest obstacle to hope for the
nearly 30,000 Americans awaiting organ
transplants is a shortage of healthy individuals willing to make the vital choice to
donate such organs when they or their
loved ones die.
In the laboratory, enhanced tissue preservation media and immunosuppressive
drugs are developed. Dramatic methodologies for accurately matching donor and
recipient cells are devised. Twenty-first
century surgical instruments and techniques are mastered. But in hospital intensive care and hemodialysis units, the number of patients whose survival depends on
new organs swells by 5 percent each year.
All the milestones and medical advances
in the world simply don't work without
organ donors.
Transplant surgeons and organ procurement officials agree that despite required request laws and similar recentlyenacted measures, a critical donor shortage remains. The average wait for a kidney
transplant increased from 126 days in
1988 to more than a year in 1991. Some
potential kidney recipients wait more than
five years for the right donor to surface.

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donor kidneys, the 2,321 awaiting liver
transplants and the 2,686 who needed
new hearts. Add to these statistics 127
patients in need of a pancreas, 775 who
needed joint kidney/pancreas procedures,
964 awaiting lung transplants and 181
who needed heart/lung procedures.
The numbers are sobering, even more
so when one considers that 25 percent of
these patients will not live to realize a
second chance at life.
"The waiting lists are so long because
individuals are being diagnosed more rapidly with end-stage organ disease," according to Elizabeth A. Me amara, R.N. ,
M.S.N. , director of procurement at The
Upstate ew York Transplant Services,
Inc. "More patients are coming in sicker
and being diagnosed quicker.
"Individuals waiting for heart, lung,
liver and heart/lung transplants usually
end up becoming very ill before their
transplant. Sometimes, they're too ill to
undergo the surgery," she adds.
jacob Bergsland, M.D., assistant professor of surgery at UB, is a cardiac transplant
surgeon affiliated with the Buffalo Heart
Surgical Associates. He echoes Anthone's
concerns about the donor shortage and
elaborates on an added wrinkle for patients
awaiting hearts instead of kidneys.

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"The nature of the ..
problem for cardiac
patients is that, unlike
dialysis for kidney patients, we don't really
haveaback-upsystem,
except for mechanical
devices which are not
perfected. Our patients tend to die
within one or two
years unless they're
transplanted. Also,
each donor has only
one heart, versus two
kidneys," says
Bergsland.
While Bergsland
sees a "stagnation" in
the number of potential heart donors, he
adds that "the number
on the waiting list
slowly goes up, though
it is limited due to the
nature of heart
disease."
Further contributing to the problem,
according to the cardiacsurgeon, has been
the recent explosion
in the number of heart
transplant centers nationwide. Of the approximately 2,000 cardiac transplants perfomedannually, about
75 percent are done in the United States.
As of December 1987, there were 114
heart transplant centers in the country,
according to U OS. By 1988, the year the
first ew York State-certified center was
established at The Buffalo General Hospital, this number had grown to 135. Today,
there are 158 cardiac transplant centers.
"There are too many centers," emphasizes Bergsland. "Fifteen hundred transplants ... is not enough [per center] to
keep people in shape to perform these
operations. Also, the cost goes up with

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fewer numbers, and it's more difficult to
answer key scientific questions. For a
successful clinical study, you need more
patients per center. It is society's responsibility to make sure this is handled properly. Transplant centers can't be used for
advertising or prestige purposes."
The cloud hanging over progress in
transplantation does, however, have a silver lining. Several of them, in fact, as
illustrated by recent technological breakthroughs in such areas as tissue matching,
surgical procedures, tissue and bone
preservation and immunosuppressive

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agents to battle organ
rejection.
Kathleen Polanski,
a Buffalo-area school
bus driver, was diagnosed with systemic
Iu pus erythematosus at
the age of 16. Within
six years, her disease
had caused kidney
damage so severe that
dialysis was the only
answer. Standing in the
way of a successful
transplant was the fact
that her lupus produced various antibodies that reacted not only
with potential donor
tissue, but with her own
as well. Three times,
positive crossmatches
between Polanski and
potential donors ruled
out transplant surgery.
Crossmatch procedures to manually and
visually measure antibodyreactivity failed to
distinguish between
antibodies related to
the patient's lupus and
· those which could have
caused rejection of a
donor organ.
The answer to this
dilemma and an increasing number of
perplexing cases-lies in flow cytometry,
a process of tissue matching that uses laser
beams to measure the light properties of
various types of tissue cells. Only 12
facilities nationwide are accredited by the
American Society for Histocompatibility
and Immunogenetics to use flow cytometry
as a predictive index in transplantation.
One is at Buffalo's Erie County Medical
Center and directed by Thomas C.
Shanahan, Ph.D., associate professor of
microbiology at UB.
In addition to lupus patients in need of

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�ecause it offers this heightened
degree of sensitivity in detecting
immune responses and helps eliminate some candidates from unfair
exclusion from organ transplants)
flow cytometry is a giant step in addressing the organ donor shortage.
techniques for pancreas implantation as
the most promising area of development
in his field. Utilizing a process known as
the bladder drainage technique, in which
the duodenum is anastomosed to the bladder, surgeons are now able to implant the
pancreas along with a section of the duodenum. This has resulted in reduced rates of
post-operative complications and improved chances of detecting early organ
rejection. Kidney/pancreas transplants,
performed routinely for only the past five
years, are vital to approximately 4,000
Americans each year, most of whom have
been diabetic since their youth.
Breakthroughs in surgical technology
have led to new promise for patients who
need cornea transplants, as well. Transplant surgeon james]. Reidy, M.D., cites
the example of the surgical microscope
and the trephine blade, the latter of which
is now used in 75 percent of cornea transplant cases.
"The trephine blade is basically a hightech cookie cutter," explains Reidy, assistant professor of ophthalmology at UB. "It
looks like a small, round cutter with a
razor-blade edge, and it cuts a circular

transplants, flow cytometry is effective in
cases ofindividuals who take certain drugs,
such as hydralazine for hypertension and
procainamide for heart disease, which
produce antibodies similar to those lupus
patients produce.
"Old methods [of tissue matching]
couldn't distinguish between harmful and
non-harmful antibodies. Therefore, some
patients were unfairly excluded," explains
Shanahan. "In some cases, patients' antibodies may react against tissue, but this
may not rule out a transplant. These
patients may produce antibodies which
mimic rejection."
Because it offers this heightened degree
of sensitivity in detecting immune responses and helps eliminate some candidates from unfair exclusion from organ
transplants, flow cytometry is a giant step
forward in addressing the organ donor
shortage. In Polanski's case, it allowed her
surgeons to perform a successful kidney
transplant in 1989.
Rabie Stephan, M.D. , a transplant surgeon and clinical assistant instructor who
is working to establish a kidney/pancreas
center based at UB, sees new surgical

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hole in the cornea. It is used to cut out
damaged corneas and replace them with
donor corneas, which are sewn in with
stitches one-third the diameter of a human hair. "
The story of a patient who literally has
a brighter outlook on life as the result of
these amazing instruments is perhaps their
best testimonial.
Marilyn Foit, a suburban Buffalo
woman in her mid-40s who is working
toward a masters degree in special education, literally couldn't see to read the blackboard before Reidy transplanted her left
cornea in 1987. Five years later, she
underwent a transplant in her right eye.
She had suffered since her childhood from
keratoconus, a cornea disease that causes
progressive astigmatism and had rendered
her legally blind.
Following the success of her first transplant, Foit returned to school. "I started
school 20 years ago and I've finally been
able to return," she says triumphantly.
A year after the first transplant, when
her cornea had sufficiently healed, Foit
was fitted with a standard contact lens to
replace the cumbersome, uncomfortable

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�"The donor situalens she had been
tion
is pretty good in
forced to wear to corBuffalo,"
says Edward
rect her vision. "I
H.
Simmons,
M.D., UB
looked in the mirror
professor
of
orthopedic
and started laughing
surgery. "Thesupplyis
and said to the techniapproaching the decian, 'I've aged 20
mand, within reason.
years!' I could finally
Once bone is tested, culsee! It was the same
tured and frozen, it can
What this country needs is more of a "can-do" attitude about
feeling l had when getbe
kept indefinitely. "
tingglasses at age nine.
organ and tissue donations. Misconceptions such as these are
Bone
allografts are typiAll of a sudden, life
cally
either frozen or
a big part of the reason why nearly 30,000 Americans can only
became easier," she
freeze-dried,
depending
recalls.
wait - and hope for a second chance at life:
on
whether
or not the
Fait's right eye is
accompanying cartilage
still healing; in her left
MYTH: ''I'm too old to be a donor. "
must be preserved.
eye, she enjoys 20/20
FACT: Organ and tissue donors range in age from newborn to 70
Bone grafting is
vision with a standard
years.
probably
the oldest
contact lens.
form
of
transplantation,
MYTH: "My loved one's body will be disfigured. "
Compared to the
according to Simmons.
FACT: Skilled surgeons harvest organs and tissues in such a way that
dire shortage of organs
He notes that autothe body is in no way visually marred by the surgery.
such as kidneys and
genous spine fusion
hearts, donor corneas
MYTH: "He never signed a donor card, so we can't agree to give up his
procedures were perare relatively easy to
organs."
formed in the United
find. Because tissue
FACT: Signing a donor card is important, but not necessary. ext of
States
as early as 1911.
matching generally is
kin have the final say regarding organ and tissue donation.
"When bone graftnot required because
ing was first being done,
the cornea is avascuMYTH: "It's against my religion. "
all
grafts were autoglar and corneas may
FACT: Today, every major U.S. religion supports the concept of organ
enous, and a patient's
be preserved for up to
and tissue donation.
own bone continues to
two weeks after harbe the gold standard
vesting, a generous
MYTH: "Organ donation is expensive."
against which all others
number of eligible
FACT: A donor bears no financial responsibility for the costs related
are judged," notes Euto transplant surgery. -Diane Zwirecki
donors exists. Each
gene R. Mindell, M.D. ,
year, 40,000 corneas
professor of orthoare transplanted in the
plant patients is the fact that, although 10 paedics and director of UB's division of
United States.
"Corneas may be harvested up to six to 20 percent of patients suffer rejection orthopaedic oncology. "However, 20 to
hours after death," Reidy says. He sees the episodes, 90 percent of these can be treated 30 years ago , it was discovered that the
development of specialized preservation with topical eye drops that are not only sites from which grafts were taken somemedia as a milestone and describes this effective but inexpensive. The drops cost times had residual disease symptoms. And,
media as "similar to that used by scientists between $5 and $30 for a month's supply there were situations oflarge defect where
- compared, for instance, to immuno- much bone was needed. Then, surgeons
to grow cells outside the body."
Unlike organs that derive their nutri- suppressive agents for renal patients that began to use bone allografts. "
Allografts are common in cases oflimb
tion from the body's blood supply, cor- may cost in excess of$100 for 100 tablets.
cancer,
severe trauma and total joint failSupply
and
demand
come
close
to
a
neas derive oxygen from the atmosphere
balance
for
patients
who
need
bone
graft
ure.
"In
order to save a tumorous limb,
and glucose from inside the eye itself. It is
this difference in makeup that makes this procedures to treat cancer, trauma, failed surgeons dissect 10 to l2 inches of that
joints or similar orthopaedic problems, limb and fill the defect with cadaverous
type of preservation possible.
bone," explains Mindel!. "If a total hip or
Also working in favor of cornea trans- according to UB surgeons in this field.

Organ Donations

~e~un~ln~ t~e m~t~s

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�knee which has been in place for 10 to 15
years fails, reconstruction is done to avoid
a shortened leg after joint removal. The
use of allografts in these cases is increasingly common."
Fresh-frozen grafts are necessary in
cases where cartilage as well as bone must
be preserved to ensure a successful transplant. lf cartilage is not needed, freezedried bone is sufficient.
Approximately 25 bone banks nationwide provide both large bone and bone/
cartilage allografts. In Buffalo, Mindell
performs a bone graft every one to two
weeks, includingseverallimb-sparing procedures each year.
Transplant surgeons in various disciplines agree that improved immunosuppressive agents, several of which have become available only during the past few
years, have led to great strides in the success of organ transplantation procedures.
Kidney recipients usually rely on one
of three kinds of immunosuppressants:
cyclosporine, steroids or imuran. A new
weapon in the arsenal is known as OKT3 .
"OKT3 is directed against cytotoxic lymphocytes, as opposed to other immunosuppressive agents which are non-specific
to the lymphocytes that cause rejection,"
says Anthone.
In the realm of cardiac transplants, a
new drug known as FK 506 bears some
similarity to cyclosporine, according to
Bergsland, who notes "most patients have
some type of rejection, usually during the
early phases following a transplant."
A single donor can help as many as 200
people in need of new organs and tissue.
Technological history is made over and
over via the introduction of new equipment, new drugs, new talent and new
techniques. But for those who are waiting,
the numbers and the scientific breakthroughs often don't add up to a healthy,
hopeful future. Unless more people are
willing to donate organs and promote the
concept of organ donation, the waiting
game for many potential organ and tissue
recipients will be lost.
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�Roswell Park uses
PCR diagnosis to
help ensure the
safety of potential
organ donations

n a first-of-its-kind agreement in
New York State designed to ensure
that transplanted organs and tissues are HIV-free, Roswell Park
Cancer Institute has recently been
commissioned by Upstate New York
Transplant Services (U YTS) to
perform polymerase chain reaction
(PCR) diagnosis on all potential
donor specimens.
"Concerns about undisclosed
HIV infection were underscored earher this year in reports published in
the New England journal of Medicine and the journal Lancet, which
documented cases of HIV -infected
individuals who had tested negative on
serological examination and who were
inadvertently used as tissue or organ donors," according to Steven]. Greenberg,
M.D., UB assistant professor of neurology
and chairman of the Roswell's neurology
department.
Greenberg, who came to UB two years
ago from the National Institutes ofHealth,
says that with PCR testing, "basically, we
can ask, 'Is there a retrovirus present?'
Unfortunately, if an individual is HIVinfected, it can take up to six weeks before
an antibody level can be detected by normal serological techniques. This is a more
sensitive test which can be done rapidly
with a turnaround time of only about eight
hours."
Steven J. Greenberg, M.D., in
his lab at Buffalo's Roswell
Park Cancer Center.

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Greenberg attributes the relatively recent capability to test potential donor tissues and organs not on the PCR technique
itself- which already existed and, in fact,
is routinely used in forensic science to
type blood products and semen - but
rather, on "a rather ingenious application
of existing methodologies and an existing
understanding of how molecular engineers put things together.
"What has helped to automate the process and make it more widespread,"
he adds, "have been the more recent developments. The technology had to play
catch up. "
Greenberg credited the development
of the automated DNA thermal cyclerwhich runs the PCR based on a software
program the investigator downloads and the cloning and production-scale availability of a thermal-stable polymerase
enzyme.
Consisting of three separate reactions
"repeated ad nauseum ," according to
Greenberg, PCR "allows one to take a
needle in a haystackandamplifyit to make
a haystack full of needles." The "haystack
full of needles" is the amplified genetic
material- be it virus, bacteria, fungus or
protozoa- of whatever the investigators
are testing for.
In the first step of the reaction, performed at high temperatures , duplex
strands of DNA are melted apart. The
second - or annealing step - "allows
primers to anneal with either strand of the
DNA to , therefore, frame the genetic tar-

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get of interest," according to Greenberg.
The final step is the polymerization step,
in which DNA is synthesized for the ends
of both primers, using DNA as a template.
The reaction doubles the amount of
existing material, which then is synthesized exponentially. The amount of material- of "haystacks full of needles" depends on the amount of cycles the
reaction is programmed for. For 30
cycles, for instance, the material- synthesized exponentially - is multiplied
by one billion.
"There are two main reasons for using
this," Greenberg explains. "It is excruciatingly sensitive, and independent of a
host immune response. "
That independence from the host immune response will help eliminate the
"window of vulnerability" between the
time a person is actually infected and his
immune response is activated that often
exists in the screening process for donor
organs and tissues.
According to Eugene R. Mindel!, M.D. ,
director of UB's division of orthopaedic
oncology, "the number-one question I
hear from patients is 'will I get AIDS from
my allograft?"' And though the safety of
this and other transplant procedures has
greatly increased, the AIDS question continues to permeate all aspects of medicine
- transplantation being no exception.
Answering this query can only help to
enhance the overall success rate of organ
and tissue donation.
+
- N AN ET TE TRAM O N T

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lie health professionals.
Mahoney wrote his doctoral dissertation on temporal mortalitypattemsamong
the Seneca Nation oflndians, the first such
study to have been done wi.th the Senecas.
The study compares the mortality rates
among specific age groups within the Seneca Nation to the mortality rates of other
New York State residents in the same age
groups. The research found unusually
high mortality rates among the Senecas,
especially due to cancer.
The study has lead to a refinement and
refocusing of the Seneca ation's public
health programs, pinpointing specific areas, such as cancer, which wi.ll receive

Med student winsAmerican
PublicHealth research award
artin C. Mahoney, Ph.D. , has won
the 1992JayS. DrotmanMemorial
Award from the American Public
Health Association for his work in
public health.
Mahoney, a member of the class
ofl995, received the award and presented
his research at the APHA's annual meeting last ovember in Washington, D.C.
The award, established in 1979 by
Peter Drotman in memory of his late
brother, recognizes promising young pub-

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more attention and further research.
Mahoney earned his master's and doctoral degrees from UB.
He has been a research scientist with the
New York State Department of Health Bureau of Cancer Epidemiology and director of
the bureau's Cancer Surveillance Program.
He is a founder and member of the
steering committee of the ational Cancer Institute's Network for Cancer Control Research in American Indian and
Alaska ative Populations, and has initiated a survey of state public health agencies' sponsorships of cancer prevention
and control services for Native
Americans.
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�Donald Rennie,M.D, senior UB
counselor and vice presideni dies
onaldW. Rennie,M.D.,67, a former
UB vice president and vice provost,
died December 28, 1992, in Myrtle
Beach, South Carolina, while on
vacation.
A senior counselor to UB President William R. Greiner, Rennie had served
as a faculty member in the department of
physiology at the medical school for 34
years. He was named vice president for
research in 1980 and assumed the additional responsibilities of vice provost for
research from 1990 until last December,
when he was named a senior counselor in
the areas of research and sponsored programs, a position of cabinet rank.
Greiner described Rennie as "a wonderful, sensitive and wise person; a man
who all of us really admired. Don was our
senior counselor for the last 10 years,
someone Steve Sample and I wanted at the
table for his wisdom."
Rennie joined the UB faculty as an
assistant professor of physiology in 1958.
He was promoted to associate professor in
1962 and named a professor in 1966.
Rennie was a visiting professor at
Laboratorio di Fisiologia at the University
of Milan, Italy, from 1966 to 1967. In
1968, Rennie assumed the responsibilities
of associate chairman of the UB physiology department, was named acting chairman in 1971 and served as department
chairman from 1973 to 1980. While serving as a vice president and vice provost, Rennie continued to teach
physiology.
Rennie received
his medical degree
and a master's degree in physiology
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of Oregon School of Medicine. He did a
postdoctoral fellowship there as well as at
Harvard Medical School.
A member of the editorial boards of the
American journal of Physiology and journal of Applied Physiology, Rennie had
served on the Porter Fellowship Committee of the American Physiological Society,
Test Committee for Physiology of the
ational Board of Medical Examiners and
as an ex-officio member of the Educational Committee of the American Physiological Society.
Donations in his memory can be made
to the Donald W. Rennie Memorial Fund,
in care of the University at Buffalo Foundation, and sent to the Department of
Physiology, University at Buffalo, 122
Sherman Hall, Buffalo, NY 14214.
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needed for optimal function.
A member of the American Institute of
Nutrition, the American Association of
Cancer Research and the American Heart
Association's Basic Science Council,
Spence joined the UB faculty in 1980. He
was appointed associate dean in 1988 and
held a joint appointment as research asso+
ciate professor of nutrition.

Above, about 50 physicians attended the second
annual "Prep for Practice," held last October.
Below, about 200 students, staff and alumni
attended this year's senior reception at the
Marine Midland (enter.

Spence leaves UB to head USDA
research center in Maryland
oseph T. Spence, Ph.D., former associate dean for research and graduate
studies, has become the new director
of the U.S. Department ofAgriculture's
Beltsville, Maryland, Human utrition Research Center.

Below, faculty and staff view the exhibits
entered in the 12th annual Medical Student
Research Forum.

ter - one of five nutrition research centers
operated by the USDA's
Agriculture Research
Service. He oversees
nutrition studies ranging from how many
calories are burned in
today's lifestyle to how
much of the ultra-trace
elements chromium
and selenium are

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UB wins Robert Wood Johnson
Foundation planning grant
B's School of Medicine and Biomedical Sciences has received a
$150,000 grant from the Robert
Woodjohnson Foundation to plan
new ways to select and train students to become primary care physicians.
UB is one of 18 medical schools, selected from 83 applicants, participating in
the first phase of the foundation's Generalist Physician Initiative to increase the
number of pediatricians, general internists and family practice specialists.
As a recipient of a planning grant, UB is
in a strong position to secure a $2.5 million implementation grant from the foundation.
"UB's medical school and teaching hospital system are honored to be numbered
among the 18 recipients of a Robert Wood
johnson Generalist Physicians Grant," said

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others about their use.
joseph L. lzzo, Jr. , M.D., professor of
medicine and pharmacology and program
director, said specialists with a knowledge
of drugs and drug interactions are in critically short supply.
"The shortage of clinical pharmacologists is occurring at a time when the number of new drugs under development and
the need for drug-related education are at
an all-time high," lzzo said.
The program - one of four nationwide - is expected to grant two or three
fellowships for the first year. The fellowships are aimed primarily at physicians
who would choose clinical pharmacology
as a subspecialty, but qualified doctoral
candidates also will be considered, lzzo
said.
The UB program offers two avenues of
entry: a two-year certification program
following a residency or other postdoctoral
training, or a unique four-year program
combining a residency in internal
medicine with a clinical pharmacology
+
fellowship.

john P. aughton, M.D., vice president
for clinical affairs, dean of the medical
school and director of the project.
"The faculty is committed to developing an outstanding educational experience to help correct a major manpower
deficiency in American health care. This
grant will help develop throughout our
region those programs necessary to encourage future medical students to become generalist physicians."
The medical school launched its own
primary care initiative in graduate medical education last September, unveiling a
$5 million demonstration project involving six Buffalo teaching hospitals, Medicaid and four private health care insurers.
The Robert Wood johnson initiative aims
to reach students even earlier, starting at
the high school, undergraduate and medical school levels.
One project involves working with the
14 area hospitals to identify promising
high school students to work during the
summer with community physicians.
Projects are also underway to increase the
emphasis on primary care in the medical
school curriculum and add more out-ofhospital teaching sites.
The Robert Wood johnson Foundation, headquartered in Princeton, ew
Jersey, is the nation's largest philanthropic
organization dedicated to improving health
+
care in the United States.
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UB receives clinical pharmacology
grant to launch pilot program
he University at Buffalo has received
a $3 million grant from the U.S.
Food and Drug Administration to
establish a pilot program in clinical
pharmacology aimed at relieving
the shortage of specialists trained to
develop and test new drugs and teach

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�A

Spoonful

of

Humor

©

Stu

Silverstein,

M.D .

Leaving them laughing
Think back to the last conference you
attended. That first lecturer, he watss~t~h~e;::::;::;::;:;;::;::::=;
obel Laureate from ew Zealand ..
you came to hear. His CV is recited
in a British accent by the chairman of
neurology (who was raised in Brooklyn) . This world-renowned speaker
approaches the podium and begins to
speak. You become intrigued by the
stain on his jacket and obsessed with the
phone bill you forgot to pay, or did you
pay it ... or didn't you?
The lights go out, the slides go up. You
close your eyes for "just a second" because
of the lead in your eyelids. It's now 11:30;
the lecture ended 45 minutes ago. All you
remember is his bowtie and your
drool-covered collar.
What went wrong? Why do
some people grab the audience's attention from the start? Chances are they use
humor in the form of appropriate, wellplaced jokes, anecdotes and asides. But
most people claim they can't use humor
in their talks for a number of reasons.
Theoneihearmostis, ''I'm not funny ,"
or, "Ican'tcomeupwithmaterial." While
it's true most people are not naturally
funny, most don't know how to ice skate
erence becomes
naturally either (including members of
How do you
the Buffalo Sabres), but it is something make a small fortune in medical practice?
that can be learned. And coming up with Start with a large one.
the material is not as hard as you think.
The same can be done with anecdotes.
One of the easiest ways is to "switch" an Here is a switched joke to a medical theme.
old joke and replace the details with mediAt the circus, a strongman takes a lemon
cal references. The result is a new joke that and squeezes it. At first, the juice dribbles
is essentially original. Comedy writers did out quickly, then slows down until not a
this during the past four years, when Pol- single drop comes out. The ringmaster
ish jokes were switched to Dan Quayle offers $200 to anyone who can squeeze
jokes. Andbytheway, virtually all "ortho- even one more drop from the lemon. Two
paedic" jokes are restructured Polish jokes. pumped-up bouncer types step up and
Suppose you want to comment on the squeeze until they're red in the face. otheconomic hard times of medical practice ing comes out. "Does anyone else wish to
today. Followingisanexampleofaswitched try," says the ringmaster.
joke. The originalis from jewish Humor by
A frail-looking man steps forward. The
joseph Telushkin (Morrow 1992).
crowd begins to snicker. He picks up the
How do you make a small fortune in lemon, squeezes it and a cup ofjuice pours
Israel? Come up with a large one ... with out. Stunned, the ringmaster asks, "Who

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are you? What do you do? "
"Arnold Mills, Blue Cross
claims department. "
If you were using this joke to
begin a talk on collecting from third
party payers, you could add, "Billing
and collecting from third party payers
is difficult and sometimes you have to
be a little like Arnold Mills to make it in
practice. Making it in medical practice in
the '90s is what I'll talk about today. "
When using a "funny story," it's best not
to begin by saying, "Here's a joke." It's better
to say, ''I'd like to start with a story." The joke
you start with should relate to your topic.
Following is a joke derived from old
jokes and how to use this to lead into a
serious talk.
A young man walks into an internist's
office, rushes up to the receptionist's desk
and says, "I understand my father has
owed you for an office visit for three years
now. " The receptionist replies, "Yes, have
you come to settle the account? "
"No," says the man. "I've come to get
health care on the same plan he has. "
"The cost of health care- and paying
for it - are uppermost on the minds of
most Americans. Today, I'd like to discuss
ways we can make it more affordable ... "
Here's another joke with a medical
theme. In hospitals in heaven, internists
order the fluids , orthopods set the fractures, psychiatrists do the talking, gynecologists do the pelvics. In hospitals in
hell, orthopods order the fluids , gynecologists set the fractures, internists do the
talking, psychiatrists do the pelvics.
If you look at every joke as an opportunity to come up with a funnier one with a
better theme, you will soon have more
jokes than you know what to do with. +
References:
A Funny Thing Happened on th e Way to th e Boardroom,

Michaellapoce (Wiley 1988)
Us ing Hum or f or Eff ecti ve Business Spealling, Ge ne Perrell
(Sterling 1989)
Stu Silverstein , M.D., president of Standup Medicine
Seminars of San Francisco , California , lectures nationwide on humor in medicine.

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�Gianturco named chair of St
Joseph department of surgery
ichael]. Gianturco, M.D., a 1955
graduate of the School of Medicine and Biomedical Sciences, has
been appointed Chairman of the
St.Joseph Hospital Department of
Surgery.
A board certified general surgeon,
Gianturco has been on staff at St. Joseph
Hospital for 29 years and is currently
medical staff president. He is a member of
the Buffalo Surgical Society, Western New
York Vascular Society, Baccelli Medical
Club, Erie County Medical Society, ew
York State Medical Society and American
+
Medical Association.

Michael J. Gianturco, M.D.,'SS, in his Amherst restaurant, Michael's Plum.
Wels, a clinical professor of surgery at
UB and distinguished alumnus, was recently appointed chair of the University at
Buffalo Council by Governor Mario M.
Cuomo. Chairman of the department of
surgery at Millard Fillmore Hospitals from
1987 until1989, Wels completed his residency in surgery at the former E.]. Meyer
Memorial Hospital, Buffalo, New York.
He received the Distinguished Alumnus
Award in 1979 and the Samuel P. Capen
Award in 1981. A trustee of the University
from 1972 to 1976, he has been a trustee
emeritus since 1979.
Hess, director of the Perinatal Monitoring Program at Yale- ew Haven Hospital (Y NH), Yale University School of
Medicine, completed his residency in
surgery, gynecology and obstetrics at
New Haven Hospital, ew Haven, Conn ecticut. He is also co-director of the
Y HH Fetal Heart Institute and Fetal
Cardio-Vascular Center. Hess is a diplomate of the ational Board of the American Medical Association, past-president
and a member of the Connecticut State
Medical Society, a fellow of the Ameri-

Alumni Association announces
first Achievement Award winners
our UB physicians will receive the
first annual Alumni Achievement
Awards - one of them posthumously- at this year's Spring Clinical Day luncheon.
The awards, which recognize a
select group of UB medical alumni who
have made their mark in a particular area
of medical endeavor, will be given to Philip
Wels, M.D., '41; Orvan Hess, M.D., '31;
Kenneth Altshuler, M.D., '52, and posthumously to 0. P. Jones, M.D. ,'56.
In establishing the awards, the Alumni
Association wants to laud alumni who
have distinguished themselves in areas
such as research, teaching, technical innovation, private practice, community service and school administration, according
to Donald P. Copley, M.D., '70, Alumni
Association president. In each case this
year, he added, the recipients have made
outstanding contributions in one or more
fields.

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can Board of Obstetrics and Gynecology
and the American College of Surgeons
and a fellow of the American College of
Obstetrics and Gynecology and pastchairman of that organization's Committee on Anesthesia and Analgesia.
Altshuler, professor and chairman of
the department of psychiatry at the University of Texas Southwestern Medical
Center, completed residencies in psychiatry at the Bronx Veterans Administration
Hospital, Bronx, New York, and the ew
York Psychiatric Institute. A fellow of the
American Association for the Advancement of Science, the American College of
Psychoanalysts and the American College
of Psychiatrists, Altshuler is also a member of the American Medical Association
and a life fellow of the American Psychiatric Association.
0. P. Jones, UB professor emeritus of
anatomyandassistantmedicalschooldean
who died in 1989, was recognized as one
of the world's experts on the morphology
of red blood cells. He also received the
Distinguished Research Award from the
Buffalo Chapter of Sigma Chi for pioneer-

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�ing the use of advanced microscopic techniques in hematology.
The awards will be given prior to the
Stockton Kimball lecture on Saturday,
+
May l.

Alumni Association establishes
scholarship endowment fund
o help further the medical school's
goal to seek students of all means,
the Medical Alumni Association has
announced it is establishing an
Alumni Scholars Endowment Fund
out of donations received from reunion classes at Spring Clinical Day and
Reunion Weekend.
"This year's donations will be pooled
together in one fund," explained Alumni
Association President Donald P. Copley,
M.D., '70. A goal of $1 million, to be
collected over five years, has been set,
Copley added; the interest would be used
to fund 10 scholarship awards one
made for each of the 10 reunion classes.
"The size of the award would likely be
$1,000 per year for four years," Copley
said. "There would be 40 such awards at
any one time- and we hope to continue
them indefinitely," he added.
The first awards will be given April30
at the Reunion Class Cocktail Receptions
+
held at the Center for Tommorow.

Spring Clinical Day and Reunion
Weekend set for April30, May 1
he Medical Alumni Assocation has
set Saturday, May 1 for the 56th
annual Spring Clinical Day. Mark
your calendars and plan to attend!
jamesS. Todd, M.D., executive vice
president of the American Medical
Association will deliver the keynote address, "The Name of the Game."
Reunion classes of 1943, 1948, 1953,
1958,1963,1968,1973,1978, 1983and
1988 will meet for Cocktail Receptions on
Friday, April 30, at UB's Center for Tomorrow, and on Saturday, May 1 for Reunion Dinners. Those classes will be vying
for the Best Attendance Trophy, won last
year by the Class of 1952.
+

1992 Reunion Class Donations

New med school alumni directory
to be published in June 1994

Donations from last year's Reunion
Classes totaled nearly $80,000.
Following is a summary of the gifts.

he Bernard C. Harris Publishing
Company, Inc., will produce a new
medical alumni directory.
Scheduled for publication in june
1994, the directory will contain facts
on over 5,200 medical school graduates, including their current names, addresses and telephone numbers as well as
academic and career information. The
Harris Company will begin mailing questionnaires to alumni in the near future; if
you prefer not to be listed in the directory,
please contact the Alumni Affairs Office in
writing as soon as possible.
+

Class Year .. #in Class .. #of Dooors ...... Total Gifts

1942 .........41 ........... 18 ................. $8,077.13
1947 ......... 52 ........... 12 ................. $5,850.00
1952 ......... 54 ........... 26 ............... SI 0,225.25
1957 ......... 61 ........... 22 ................ $ 5,925.00
1962 ......... 66 ........... 19 ............... $13,875.00
1967 ......... 92 ........... 42 ............... S14,525.00
1972 ......... 117 ......... 31 ................ $ 9,425.00
1977 ......... 134 ......... II ................ $ 3,925.00
1982 ......... 138 ......... 18 ................ $ 4,625.00

s

1987 ········· 144 ......... 27 ................ 2,050.00

B

u

0

0

p

h

y

o

n

5

p

James S. Todd, M.D.

AMA executive to deliver Spring
Clinical Day keynote address
ames S. Todd, M.D., executive vice
president of the American Medical
Association, will deliver the keynote
address for this year's Spring Clinical
Day lecture.
A general surgeon from Ridgewood, New jersey, Todd joined the AMA
in 1985. Before that, he was a member of
the organization's board of trustees as well
as a commissioner to the joint Commission on Accreditation of Hospitals.
Todd graduated cum laude from
Harvard Medical School and interned and
served his residency at Columbia Presbyterian Medical Center. A diplomate of the
American Board of Surgery and a fellow of
the American College of Surgeons, he has
been a director of the Institute of Society,
Ethics, and the Life Sciences (Hastings
Center) and has published numerous articles dealing with health care and professional liability.
On May 1, he will talk about 'The
Name of the Game" at Spring Clinical
+
Day.

9

9

3

�•

··························································································

I

1

9

3

s

0

won the APA's Newsletter of the
Year in 1992.

CARLJ . STREICHER '35 ,

is enjoying retirement in Lake
Havasu City, Arizona. He plays
golf five times a week and has a
new home built on a golf course.
BERNARDS . STELL '36 ,

a retired psychiatrist writes, "In
three international photo salons
sponsored by the Photographic
Society of America, my stereo
slides won awards. Because most
of my photographs are close-ups,

ARTHUR J .

tion of the various mal positions of
the eyelids.

tronic flash units that I use are
also synchronized at speeds up to

DONALD

practice in thoracic and cardiovascular surgery in Cincinnati,

1

9

5

s

0

F. DOHN '52 ,
reports that he is busy with coastal
cruising (sailboat) , camping and
travel after retiring from the practice of neurosurgery in july 1991.
EDWARD W. HOHENSEE
'54 , retired in June from the

have a Diamond Star in PSA Competitions. ow I am accumulat-

ogy. After a total hip replacement

private practice of ophthalmol-

HILLIARD

1

9

4

s

0

THEODOREW . KOSS '4 1 ,

writes, "I am comfortably retired
nearCenterhillLake,Tennessee. "
GILBERT

B .

TYBRING

'45 ,edits the Wisconsin Psychia-

trist, the Wisconsin Psychiatric
Association's newsletter, which
B

a

' 58 ,

book co-authored with his wife,
Jane Westberg, Ph.D., Collaborative Clinical Education: The Foun-

died December 1, 1992. A tuberculosis researcher after his graduation from medical school, he did
private practice in Buffalo for
nearly half a century, retiring in
the early 1980s.

dation of Effective Health Care,
published by Stringer Publishing
Company in 1992. Jason is currently executive director of the

died October 3, 1992. Slocum

Center for Instructional Support
(a non-profit educational service)

system. Heleft Texas in 1952 and

in September, he reports that he is
enjoying retirement and visiting

and clinical professor of family
medicine at the UniversityofColo-

his eight offspring.

rado School of Medicine.

ERNEST H . MEESE '54 ,

retired three years ago after 50
years of practice and is keeping
busy sculpting and writing books.

JASON

announced the release of a new

Stereographer I. "
IRVING PERLSTEIN '39 ,

OBITUARIES
CLYDE W . GEORGE '29 ,

Ohio.

some out-of-the-way place to get
unusual pictures. At present, I

ing credits for the next PSA Stereo
Division
Award,
Master

Hilliard Jason '58

Ernest H. Meese '54

physiology and surgical correc-

I do not use a stereo camera; I use
two 35 mm single lens reflex cameras whose shutters are synchronized electronically. The elec-

1/SO,OOOofasecond. Iamover80
years old, so I find it easier to set
up my photo equipment on our
backyard patio than to travel to

SCHAEFER

'4 7 , a UB clinical associate professor, attended the Advisory
Board meetings of the American
Society of Ophthalmic, Plastic and
Reconstructive Surgery and the
American Academy of Ophthalmology, in Dallas, Texas, as a
member of a team of physicians
who gave a lecture on the patho-

1

was presented the 1993 Swords-

9

6

s

0

HARVEY C . SLOCUM '32 ,

was the first professor of anesthesiology in the University of Texas
spent approximately 10 years in
military service at Walter Reed
Army Medical Center. Upon retirement from military service, he
returned to the University of
Texas; in 1979 he was named
Professor Emeritus.

man Award given by the American Cancer Society at the Annual

Beverly Hills, California, writes,

Swordsman Ball on January 16,

"My associate in practice and I

1993. This prestigious award recognizes his outstanding service
and leadership in the field of can-

have scheduled 17 radiology technology courses for mammography

EDMUND M . TEDEROUS

techs around the country. "

'43 , died December 19, 1992.

SAAR PORRATH '61 , of

cer for the past 30 years. He has
beenontheBoardofTrusteesof
the Ohio Division of the Ameri-

STEPHEN

can Cancer Society since 1979
and served as the Board's president in 1990. Meese has a private

0

p

y

5

E .

RICHARDJ . MILAZZ0 '42 ,

died October 26, 1992.

LANGER

GEORGE BISGEIER '50 ,

'67 , of Berkeley, California, has
recently been named medical director of the Wellness International etwork.

died of a brain tumor on ovember 5, 1992.
DANIEL

A .

RAKOWSKI

'60 , died December 8, 1992.

c

a

5

p

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9

��BUFFALO PHYSICIAN
STATE UNIVERSITY OF NEW YORK AT BUFFALO

Non-Profit Org.
U.S. Postage

3435 MAIN STREET

PAID

BUFFALO NEW YORK 14214

Buffalo, NY
Permit No. 311

ADDRESS CORRECTION REQUESTED

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                    <text>State University of New York at Buffalo School of Medicine and Biomedical Sciences, Summer 1993

�Dear Friends,

BUFFALO PHYSICIAN

Volume 27, Number 3
ASSOC I ATE V ICE
PRESIDENT FOR
UNIVERSITY
ADVANCEMENT

Dr Carole mtth Petro
D IRECTOR OF
PUBLICATIONS

Timothy J. Conro)
EDITOR

anette Tramont Kollig, R.N.
ART D IRECTOR

Alan J. Kegler
ASSOC IATE ART D l RECTOR

Scott Fricker
PRODUCT ION MANAGER

Ann Raszmann Brown
STATE UNIVERSITY OF
NEW YORK AT BUFFALO
SCHOOL OF MEDICINE
AND B IOMEDICAL
SCIENCES

Dr john Naughton, Vice Prestdent
for Chmcal Affans, Dean
EDITORIAL BOARD

Dr. john A Rtchert, Chatnnan
Dr. Martm Brecher
Dr Harold Brody
Dr. Rtchard L. Collins
Dr. Alan j. Dnnnan
Dr Timothy Gabryel
Dr james Kanskt
Dr Charles Massaro
Dr. Charles Paganelh
Dr Robert E. Retsman
Dr Thomas Rosenthal
Dr Stephen Spauldmg
Dr Bradley T Truax
TEACHING HOSP ITALS AND
LIAISONS

Batavia VA Medtcal Center
Arlene Kelly
Buffalo General Hospttal
Mtchacl Shaw
Buffalo VA Medtcal Center
Chtldren's Hospttal of Buffalo
Ene County Medtcal Center
Mercy Hospttal
Mtllard Fillmore Hospttals
Franl1 Sava
Roswell Park Cancer Institute
Ststers of Chanty Hospnal
Dennis McCarthy
©The State Umversity ofr\ew York at

Buffalo

Buffalo Phys1c1an IS published quarterly
b)' the State Umverstty of f\,;ew York at
Buffalo School of Med1cmc and
BiomediCal SCiences and the Orfice of
Publications. It is sent, free of charge,
to alumni, faculty , students, resadents
and fnends. The staff reserves the
right to edit all copy and submissaons
accepted for publication.
Address quesuons , comments and

I

n july, a very concrete example of the benefits of Buffalo's consortia! efforts will be
realized. The University, its Health Sciences Schools, the Health Sciences Library, and
seven of the eight teaching hospitals will upgrade the availability of reference materials
for students, residents and physicians who are based in or who use these faClhlles. This
project will be jointly funded by UB and the hospitals and will bring the total MEDline
reference system plus other biological reference systems directly to each hospital. In
addition, a large number of actual text materials and graphics can be
transmitted to the end-users or consumers. Because it is a joint
venture of all of these partners, common equipment will be used
across the educational system and the costs of adding to existing
computer information capacities, while not insignificant, are much
less than if developed in another manner.
The services will improve education and information availability
at all levels - undergraduate, graduate and continuing medical
education. My office is grateful for the leadership provided by
individuals such as john Hammond,john Loonsk and jerry Wilson,
to name just a few of the many people involved, and for the cooperative input among the
many units of UB and the teaching hospital system, which helped make this important
project a reality. Literally everyone involved in medical and health education in all these
institutions will benefit directly from this effort.
At this time, l would like to take this opportunity to announce that Buffalo Physician
magazine will begin accepting advertisements in our next issue. We are pleased to be able
to offer our readers this additional benefit of informing them of various services and
products that might be useful to them.
Sincerely,

john Naughton , M. D.

Vice President for Clinical Affairs
Dean, School of Medicine and Biomedical Sciences

Dear Fellow Alumni,

T

he Medical Alumni Association had a most successful1992-1993 year. Congratulations and sincere thanks to Don Copley, who guided the organization with wisdom,
tact and boundless energy. The basic goals were met- addressing many of the needs
of the medical students, alumni and medical school. In addition, the Medical Alumni
Board, under Don's leadership, established new alumni recognition awards, first presented at the 1993 Spring Clinical Day, and a new medical school
scholarship fund, which should serve as an acceptable and appropriate conduit for reunion class contributions to the medical school.
Spring Clinical Day, as usual, was educationally enlightening and
socially, a warm pleasurable event particularly for those celebrating
five-year reunions. We are indebted to Margaret Paroski, Class of
1980, for her direction and organization of this superb program.
With the help of an enthusiastic, dedicated Medical Alumni
Governing Board, I hope to continue to support the standards set by
my predecessors. I hope you will continue to support the Medical
Alumni Association which provides very special services, particularly to the medical
students.
Best regards,

submtss10ns 10
Editor , Buffalo
Physician, Stale Umversity o[New York
at Buffalo, Umversity Publications, 136
Crofts Hall, Buffalo, ew York 14260

Send address changes to:

Buffalo
Physician, 146 CFS Add1t1on , 3435
Mam Street, Buffalo, l'ew York 14214

Robert E. Reisman, M. D., '56

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II Research
II Hospital News
He captured my heart in a way that patients aren't
D supposed
to." • Doctors affect patients every
11

Health care reform it's no joke. Page 42.

day. But sometimes, patients profoundly affect
their physicians.

IIJ Managed Care e Containing health care costs or
physicians' autonomy?

EJ Medical School
~~ Graduate Education

Social and Preventive Medicine's Maurizio
Trevisan studies dietary habits. Page 22.

IJ Alumni
IIJ ASpoonful of Humor

m

Classnotes

*managing
rnanageo care.
rage lt
Med student Andrea Williams wins
National Medical Fellowships award.
Page 33.

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Skin cancer is the target of NIH's $5 million grant to Roswell Park Cancer Institute.

Roswell gets $5 million NIH grant
to study photodynamic therapy
esearchers at Roswell Park Cancer Institute have received a $5
million grant from the ational
Institutes of Health to conduct
in-depth clinical and basic science studies of photodynamic
therapy and skin cancer.
Pioneered at RPCI in the 1970s by
chemist Thomas Dougherty, Ph.D., photodynamic therapy (PDT) has been shown
in clinical trials conducted in the United
States and abroad to shrink or eradicate
certain solid tumors, especially those of
the bladder, breast, brain, lung and head
and neck. PDT has also become an option
for thousands ofcancer patients for whom
surgery is not possible or who cannot
tolerate additional chemotherapy and radiation. A large percentage ofPDT "cures"
have been skin cancer patients.
"An epidemic of 600,000 new cases of
skin cancer are reported in the United
States each year," said Allan R. Oseroff,
M.D., chief of Roswell's Department of
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Dermatology and principal investigator of
the IH study. "For large skin tumors,
especially those appearing on the face,
surgical removal may result in extensive
reconstruction and in some cases, disfigurement. Chemotherapy and radiation
may have a cumulative toxic effect."
PDT virtually eliminates the drawbacks
associated with more conventional treatments, without toppling the cure rates.
Over the next five years, the Roswell
researchers will assess the effectiveness of
PDT against the most common type of
skin cancer and scrutinize the mechanisms and dynamics of PDT as they explore strategies to perfect the treatment. +

Selenium-enriched garlic is just one of the
"designer foods" being tested as a cancer
preventative by Clement Ip, Ph.D., a breast
cancer researcher in Roswell Park Cancer
Institute's Division of Breast Surgery.
These days, Ip's laboratory smells like
an Italian restaurant.
In one recent study, Ip discovered that
garlic- enriched by the anticancer agent
selenium - protected animals against
breast tumors.
Selenium - a non-metallic element
that resembles sulfur - has been Ip's
major research interest for the last 15
years. "My studies and those of others,
have shown that selenium protects against
breast cancer. My goal has been to find the
best ways to incorporate sufficient quantities of selenium safely into foods. "
His choice of garlic is a natural, since the
vegetable is abundantly rich in sulfur and
has moderate anticancer activity. "Plants
convert inorganic selenium in soil to organic selenium analogs of naturally occurring sulfur compounds," Ip said. "By
substituting sulfur with selenium, we had
hoped to produce more powerful
anticancer agents in garlic."
Ip compared garlic grown in seleniumenriched soil to garlic grown in normal
soil. The selenium-enriched garlic was
far superior to regular garlic in suppressing breast cancer in experimental rats
treated with a carcinogen to induce breast
tumors.

"Designer foods"being tested as
cancer preventatives at RPCI
picures may call it the "stinking
rose," but garlic by any other name
will still carry that heady aroma potent enough to keep vampires,
and perhaps even a disease or two, at
bay.
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Garlic by any other name will still carry that
heady aroma.
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"Our research shows that by incorporating selenium into a plant that is already
rich in sulfur, the potential for cancer
protection is significantly enhanced," lp
said.
+

Agrowing population of children may be at risk
for long-term school problems.

Half of veiY premature infants
need special education services
alf of extremely premature infants
who survive into childhood may
need special education services
when they enter kindergarten.
Another 15 percent are on the verge
of needing special help, a study
conducted by UB researchers has found.
And children whose families had limited resources were seven times more
likely to need help than those in more
affluent households. Being non-white or
male each increased the risk two and onehalf times.
The study, headed by Michael E. Msall,
M.D., associate professor of pediatrics and
rehabilitation medicine, was published in
the American journal of Diseases of Children.
The research constitutes one of the first
school-readiness studies of children born
extremely prematurely during the 1980s
and treated with calf-lung surfactant extract to prevent respiratory distress syn-

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The study, headed by Carl V. Granger,
M.D. , professor of rehabilitation medicine, appeared in the journal Stroke.
Granger speculated that older patients may
be discharged from rehabilitation earlier
because they reach a plateau sooner or
because other medical problems may limit
their ability to participate vigorously in
rehabilitation.
He also raised the possibility of a bias
against older patients on the part ofyounger
care providers, who may speed up discharge because they feel older patients
+
have less potential to benefit.

drome. The treatment has dramatically
increased the survival rates of extremely
low birth weight infants.
With more children surviving prematurely, especially those weighing under
three pounds, Msall said, researchers have speculated there
is a growing population of children at risk for long-term physical problems and school difficulty.
Msall and his research team
set out to assess the kindergarten
readiness of children who survived extremely premature births
to determine factors that identify
children who might need extra
help. The cohort of 149 children
born at 23 to 28 weeks gestation
were between four and five years old at the
time of the study.
Of the 149 children, 35 percent were
observed to be ready for regular public
school kindergarten. Fifteen percent were
considered at risk of requiring special
education resources, 4 2 percent were classified as requiring modified classrooms
and 9 percent as needing extensive rehabilitative therapies and special education
resources.
Low socioeconomic status was the most
significant predictor of the need for special education help among the children
studied, followed by being non-white or
male.
+
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Older stroke patients fare worse
than younger ones,UB study finds
lder stroke patients don't recover as
well as younger ones and spend less
time in rehabilitation than do the
younger patients, according to a UB
study of the rehabilitation history of
7,905 stroke patients.

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Other health problems may limit the recovery of
older stroke patients.

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aspirin bind to the same receptor in the
platelet.
"But aspirin can't produce its effects if
ibuprofen is already there," Gengo said.
"If both drugs are taken together, the
patient will get the temporary effect of the
ibuprofen, rather than the permanent effect of the aspirin. "
The researchers are now expanding their
study to include older subjects taking
both aspirin and ibuprofen for several
+
weeks.
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OLDBAUM

Ibuprofen and aspirin don't mix.

UB team uses DNA to recreate key
Ibuprofen may diminish aspirtn's proteins to prevent tooth decay
beneficial eftects on platelets
B scientists have used recombinant
eople who take aspirin regularly to
prevent stroke and heart attack may
need to be careful about how- and
especially when - they take
ibuprofen, according to a UB study.
Published in the journal of Clinical Phannacology, the study demonstrated
that in healthy, young volunteers who
took a single dose of ibuprofen and then
took an aspirin an hour later, the ibuprofen
markedly shortened the duration of
aspirin's effect on blood platelets. But the
ibuprofen did not have the same effect on
blood platelets if taken after the aspirin.
"Both ibuprofen and aspirin inhibit
platelet activity," said Terence Fullerton,
Pharm. D., UB clinical instructor of pharmacy and director of the study conducted
at Millard Fillmore Hospital. "But aspirin
does so irreversibly for the life of a platelet
- about seven to 10 days - while
ibuprofen does so for only four or five
hours."
According to Francis M. Gengo, Pharm.
D., UB associate professor of pharmacy,
director of neuropharmacology at Millard
Fillmore and co-director of the study, the
working hypothesis is that ibuprofen and

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called mucins, that lubricate the mouth
and tooth surfaces, minimize the abrasion
of enamel and provide a moisture-rich
environment that discourages the proliferation of harmful bacteria and fungi.
Histatin possesses antifungal and antibacterial properties, Levine said, attacking the outer membrane of fungi or bacteria. While Levine said the mechanism of
cystatin is not yet clear, it also possesses
antibacterial and antiviral properties and
halts the proliferation of microorganisms.
Both proteins can help prevent the decay of tooth enamel, as well as infections
that eat away at soft tissue and bone.
Although future mou thrinses and toothpastes containing these proteins will not
replace chemical antibacterial drugs,
which, in tandem with the body's immune
system, attack colonies of several types of
microorganisms, "they'll be important in
preventing or fighting the growth of these
+
microorganisms," Levine said.

D A techniques to recreate key proteins in human saliva that help fight
bacteria, possibly paving the way
for over-the-counter products that - B Y
would help prevent tooth decay.
"Inexpensive products containing these
salivary proteins will
be used in toothpastes,
mouthrinses and oral
sprays by the turn of
the century," predicted
Michael j . Levine,
D.D.S. , UB professor
of periodontics.
The two proteins in
saliva recreated by the
UB team - cystatin
and histatin - inhibit
the reproduction of
microbes or interfere
with their activity,
which contributes to
oral diseases.
The team also is
working to recreate
two glycoproteins, Using DNA to fight tooth de&lt;ay.
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MARY

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�. . . . . . . . . . . . . . . . ... . . . . . . . . . . . . . . . . . . ... . . ... . . . . [1]
Tucker appointed director of WNY
Regional Poison Control Center

r

effrey R. Tucker, M.D., has been appointed medical director of theWestem ew York Regional Poison Control Center at The Children's Hospital of Buffalo. Tucker is a staff member at CHOB in its emergency medicine department and has been the associatedirector for the Poison Control Center.
Tucker's responsibilities include providing medical advice to the poison specialists at the Center and educating residents and medical students about toxicology. Tucker is currently involved in several research projects, including a study of
Albuterol- the medicine commonly used
to relieve wheezing in children.
Tucker graduated from Boston University School of Medicine and completed his
residency at Boston City Hospital.
He completed fellowship training
in pediatric emergency medicine
in Brown University's program
at Rhode Island
Hospital.
+

radiation over a 40- to 60-hour time period. Radiation from the pellets remains
essentially confined to the tumor area,
sparing the surrounding healthy tissue.
Roswell Park's first patient to receive
low-dose radiation using the new remote
afterloading system was diagnosed with
stage IlA cervical cancer. She had been
treated with conventional external radiation prior to this treatment.
Conventional intracavitary brachy~ therapy- the use of which was pioneered
"'~ for gynecological cancers at Roswell to
achieve the highest cure rate in the country following hysterectomy- carries with
it certain risks for those treating the paLast year's record loss exceeded $29 million.
tient. "Any persons having contact with
the patient during treatment are exposed
to be the most difficult in recent years, the - although briefly - to the radiation
report said. The overall operating loss of source," said Kyu Shin, M.D., chairman of
$7.9 million was posted in 1989; that loss the Department of Radiation Medicine.
grew by 68 percent to $13.3 million in "The risk," he added, "is minimal, almost
1990 and increased by 30 percent to $17.3 inconsequential, but our new method
million in 1991.
eliminates any potential risk of exposure."
The current loss of $29 million repreA computer-controlled robotic system
sents an increase of 68 percent over the loads and unloads the radiation sources.
previous year. Proposed ew York State "Before a person enters the patient's room,
budget cuts for 1993 would mean an addi- the robot will remove the radiation imtional revenue loss of$41.4 million, while plant and place it into a vault. When the
proposed Medicare cuts would result in a visitor leaves the room , the radiation
further revenue loss of over $20 million to sources are replaced in the patient."
Western New York hospitals. Combined
Shin and his colleagues are currently
with the 1992 operating loss, the pro- using the new procedure on patients with
posed Medicare and Medicaid cuts could gynecologic cancers.
account for a collective loss of$93 million
For more information on brachytherapy
in 1993.
+ or to refer a patient, call Roswell Park
Cancer Institute's Department of Radiation Medicine at 845-3172.
+

Western New York hospitals post
record-high operating loss for '92 RPCI oiTers computer-controlled
estern ew York Hospital Asso- low-dose radiation therapy
ciation member hospitals posted
a record-high operating loss of
$29,023,000 for 1992, resulting
in 759layoffs in 1992, according
to a report by the Western ew
York Hospital Association.
The financial performance of Western
ew York's hospitals has been declining
over the past four years, and 1992 appears

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oswell Park Cancer Institute is now
offering computer-controlled lowdose brachytherapy - a safer, more
efficient way to deliver low-dose radiation directly to tumors.
The procedure uses robotics to
implant radioactive pellets directly on or
near the tumor to deliver low doses of
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psychiatric beds at BGH to 107, including
4 7 in the main hospital building and 60 in
the hospital's Community Mental Health
Center (CMHC). Buffalo General now
operates 74 2 beds.
Philip C. oe, assistant vice president
and CMHC administrator, said the hospital has also opened two new specialty
units, one for senior adults and the other
for mentally ill chemical abuse patients.
Each unit contains 20 beds.
"Putting the 22 psychiatric beds in the
tower will help maintain a close affiliation
with medical units in the hospital," oe
said. Additional multidisciplinary staff
have been hired, including nurses, social
workers and occupational and recreational
therapists.
Opening of the new units completes the
final phase of a project begun in 1989. The
first phase, a lO-bed medical psychiatric
acute care unit, was completed in 1990;
the second phase, a 15-bed affective disor+
ders unit, was opened in 1991.

Sisters Hospital opens new lobby
and 10-unit surgical department
isters of Charity Hospital is heading
for the three-quarter mark of its 28month, $42 million modernization
project with the opening of its new
operating rooms and lobby.
The new 10-suite surgical department, which opened in March, is located
on the hospital's fifth floor next to its
recently opened intensive care unit. "It's
quite an exciting change from the old
area, which was built in 1948," said Gino
Pazzaglini, executive vice president at
Sisters. "The new space provides us with
a modern, efficient area which will allow
our surgeons and nurses to offer the best
and safest possible care to our surgical
patients."
The new rooms are larger and equipped
with the latest in surgical support systems.
The new lobby, with its heavy emphasis on glass architecture and natural lighting, features stained glass artwork, high
ceilings and banners carrying pastoral
themes of hope, peace and joy.
"From the beginning we felt the lobby
should be seen as a special place to greet
the general public, a place where they will
be made to feel comfortable and at ease,"
+
Pazzaglini said.

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Van Vorst named new Millard
Fillmore Hospitals president

Sisters Hospital nears &lt;ampletion of its $4 2
million modernization proje&lt;t.

BGH opens 22 psychiatric beds to
complete $1.6 million project
he Buffalo General Hospital has completed the final phase of a $1.6 million project with the opening of 22
psychiatric beds in its medicaVsurgical tower.
The new beds increase the total of
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illard Fillmore Hospitals' ChairmanoftheBoard, Edward T. Hunt,
announced that Charles B. Van
Vorst has been appointed the new
hospital president and chief executive officer. He succeeds jan R.
jennings, who was recently named president and chief executive officer of the
Chicago Children's Memorial Medical
Center.
VanVorst most recently held the position of president and
chief executive officer
of the Santa Rosa
Health Care Corporation of San Antonio,
Texas. The corporation is a regional, notfor-profitmulti-hospi-

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tal system consisting of seven hospitals
with 1,166 licensed beds.
During his tenure at Santa Rosa, Van
Vorst's accomplishments included the development of a new long-range strategic
plan and the implementation of a total
quality management structure.
"We are extremely pleased that Mr. Van
Vorst will be leading our hospitals and
look forward to his contributions toward
the continued success of our health care
delivery system," Hunt said. "While his
philosophies are very similar to those of
the hospitals' board, we anticipate that he
will add a new dimension which can only
serve to further enhance the level of care
we currently provide," he added.
Prior to his position at Santa Rosa, Van
Vorstspent l l yearsaspresidentandchief
executive officer of The Carle Foundation
in Urbana, Illinois, a not-for-profit health
care-related holding company that owns
and manages a number of health care
entities including two hospitals, a nursing
home and retirement center. Additionally, he held the position of vice president
for operations for Methodist Hospital of
Indiana for seven years.
"I look forward to the opportunity to
continue the momentum set forth by Mr.
jennings and lead Millard Fillmore Hospitals to even greater heights and national
prominence," VanVorst said.
+

MFH' s Hertel-Elmwood Internal Medicine Center.
diagnostic services. Thomas Small, M.D.,
has been appointed medical director of the
center.
The center will operate under a preventive medicine philosophy, administering
immunizations and vaccinations and providing information on health maintenance.
A major goal of the center is to avoid major
health problems in its patients through
+
early and ongoing intervention.

New technique for liquid breathing
discovered by UB research team
simplified technique for liquid
breathing discovered by a team ofUB
researchers could significantly improve treatment of premature infants,
children and adults with lung diseases. It could also help cut this
country's annual $5 billion price tag for
treating adult respiratory distress syndrome.
Bradley P. Fuhrman, M.D., UB professor
ofpediatrics and the team's chiefinvestigator,
has pioneered an inexpensive way to enable
the body to "breathe" perfluorocarbon. The
technique is known as perfluorocarbon-associated gas exchange, or PAGE.
Liquid ventilation shows great promise
for treating premature babies with hyaline
membrane disease and other patients with
adult respiratory syndrome. Widespread
testing of liquid breathing in humans has
been impossible in the past, Fuhrman
said, because a suitable, high-purity, me-

he medically underserved community of Black Rock/Riverside is the
location of a new primary care center run by Millard Fillmore Hospitals in conjunction with UB's School
of Medicine and Biomedical Sciences.
The Hertel-Elmwood Internal Medicine
Center offers patients 16 years and older
convenient access to medical care and
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MFH opens primary care center in
medically underserved community

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dicinal grade of perfluorocarbon did not
exist and the procedure required special
equipment.
Fuhrman's technique uses a standard
respirator, rather than a specially designed
liquid ventilator. In PAGE , the
perfluorocarbon remains in the lung while
the respirator delivers breaths of oxygen.
In standard liquid ventilation ,
perfluorocarbon is cycled into and out of
the lungs using a specially designed liquid
ventilator, which oxygenates the liquid
and purges it of carbon dioxide. When his
liquid ventilator broke down in the midst
of research on piglets, Fuhrman decided
to hook up an animal with a
perfluorocarbon-filled lung to a standard
respirator. "When I saw it worked,"
Fuhrman said, "I was exhilarated."
PAGE is significantly less expensive
than other methods of liquid ventilation
since it uses readily available equipment.
It is also kinder to damaged lungs because
it is effective at lower pressure and may
allow the use of lower oxygen concentra-

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nhalation

halation

Liquid breathing technique holds great promise for
treating children and adults with lung disease.
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�"He captu
my heart in a

way that
patients aren t
SUptxJSed to."
•

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tors affect patients every day.
But sometimes, patients
profoundly affect their
physicians. Here are their stories.

0

Buffalo

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1993

�Illustrations by Glyn

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remember my patientstheir grace, dignity and humor and triumph over adversity. Their stories are legion
and what we have to do is
train ourselves to listen and
see. They're all out there and
each has a moral of its own."

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and they couldn't come to visit him. He
was all by himself.
"So the nurses and physicians who
took care of him became his parents.
"The barriers of how I was going to deal
with this little boy were quickly broken.
He captured my heart in a way that patients aren't supposed to.
"He always wanted people to stay with
him and although he was in a lot of pain,
he rarely, if ever, cried.
"We were constantly trying to figure
out ways to try to relieve Rodney's pain.
We tried everything.
"We used to just carry him around. He
always wanted to be carried, so we would
just take turns carrying him.
"Once he wanted to know why I had to
leave- I remember this very vividly.
"He finally died and we all cried together about his death.
"That child made a very big impression
on me. He was always upbeat, always
happy to see you and always asking to go
on a trip around the ward. And he could
always con one of us into carrying him
around.
"He's probably the first patient who I
knew intimately who died. And I did
grieve for him. I have lost other patients,
and I think I remember the names of all of
them - a little bit of you dies with them
each time- but this boy taught me there
are ways you can comfort patients and
make their time more meaningful."

probably the first
patient vvho I
k.ne\v intimately

Bob Milch, M.D., '68, was
talking about his patients who
have changed him.
"You know what the definition of a minor procedure
is?" he asked. "It's a procedure that's done on someone else.
"Stories not memorable to the physician are to the patient. That's what it's all
about - minor procedures and memorable stories."
The physician-patient relationship is a
complex one -and by its very nature, one
in which it is the patient whose life is most
affected.
But sometimes, it is the physician who
is changed by a patient who shows remarkable courage, or humor, or strength,
or spirit, or pure force of will in the face of
illness and adversity.
And different patients affect their physicians in different ways- changing the
way they see or practice medicine, or
changing the way they see themselves.
These are the patients whose stories are
chronicled here.

\vho died. And I
did grieve for
him. I have lost
other patients,
and I think I
remember the
names of all of
them - a little bit
of you dies \vith
them each tin1e
-but this boy
taught n'1e there
are vvays you can

Virginia Weldon, M.D., '62,

con1fort patients
and make their

vice president for public pol icy at Monsanto.
"He was a little boy about two. I was an
intern atjohns Hopkins Hospital. He had
a neuroblastoma and it had metastasized
to his orbits and his face had become
deformed.
"I knew I was going to be on the service
he was on and i was worried about how I
was going to take care of this little boy.
"His parents lived in rural Maryland

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Donald P. Copley, M.D., '70,
past president ofUB's Medical Alumni Board
of Directors.
"I first saw KathyFreerin May ofl989.
The last time I saw her was April 13. She
was a young teacher who had had an
extremely bad heart attack in May of '89.
I never thought she'd leave the hospital, let
alone go back to teaching. We did an
echocardiogram on her which showed an
ejection fraction of 15 percent, which is
about as low as I've ever seen in anyone

time more
rneaningfu l. "

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�who's alive.
"She had a prolonged hospitalization
-at least 10 days - and I sent her home
with trepidation. Her echo was slightly
improved when she went home but still
very bad.
"We did a stress test, at least we tried,
and she did poorly - she couldn't walk
very far at all.
"She had been a busy, active teacher,
with no prior medical findings - no smoking, a family history of coronary disease,
but not remarkably bad.
"But she may be the type that goes with
blood clots rather than atherosclerosis.
We did an angiogram just before she went
home and found a single occluded artery.
My best guess is she had an atherosclerotic
plaque that produced a clot that closed the
vessel rather abruptly.
"She went home and went into a rehab
program that lasted a long time- at least
six months. She started slowly and we
weren't optimistic.
"I had thought she was close to dying in
the hospital - maybe a 50-50 risk - and
I had told her husband things were grim.
"But she is a very positive, jocular,
bubbly person. In fact, she's been accused
of being kind of cavalier- cracking jokes
about dying early. People who don't know
her accuse her of being flip.
"She has what I would call an extreme
form of an optimistic attitude. Whenever
I would describe to her the possible outcomes, she would focus on the positive.
She always passed over the negative.
"And that's the way she was in rehab,
too. She was very helpful to the other
patients. She was even ready to get on with
her life, without going back to work, which
was always very important to her. And she
was always very well-liked by the kidsshe taught middle school- and also very
highly regarded by her peers.
"She is very energetic- a Type A, an
intense coronary factor- but with none
of the hostility you associate with Type As.

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"It was a full year before she could
consider going back to work full time. And
her echo is not normal now, it still shows
the scar clearly. Her ejection fraction is
doubled what it was when she was in the
hospital and she still has a rather dilated
heart. But she's found ways to cope with
the disability."

one had ever
done exercise
testing after a

John aughton, M .D., vicepresident for clinical affairs and dean of UB's
School ofMedicine and Biomedical Sciences.
"I had one patient, Mr. Douglas Cordon, during my residency and fellowship
training at the University of Oklahoma,
who was the first to undergo exercise
testing and training after a heart attack. It
was because of him that we [Bruno Balke,
Francis agle, Michael Lategola and
aughton] developed a strategy for exercise testing and physical reconditioning
for cardiac patients.
"In 1964, Mr. Cordon indicated to me
he wanted to get into some physical activity after his heart attack. He was 54 at the
time. Two months earlier he had wanted
to enter a physical therapy program- he
had high blood pressure-and was one of
a group of healthy volunteers we were
studying. So we had the data on him
before his MI. And so two weeks post-MI
we first did an exercise test and measured
the loss. We put him on a training program. He had a higher capacity after the
training program. His work capacity increased.
"He lived another 15 years after that and always kept fit.
" o one had ever done exercise testing
after a heart attack. We had him walking
on a treadmill, and as we got more comfortable with him, we increased to 50
patients. It's an example of how you make
a change by studying one individual patient, and then adding groups of patients.
"My efforts grew from studying Mr.
Cordon well to the development of group
programs for heart attack patients and

heart attack. vVe
had him \·valking on a treadmilt and as vve
got n1ore comfortable \ vith
him , \veincreased to 50
patients. It's an
exan1ple ofho\v
you make a
change by
studying one
individual patient, and then
adding groups
of patients."

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�then to the development ,
implementation
and completion of the ational Exercise
and Heart Disease Project. ln essence, he because l don't think she looks at it as
changed my whole world. "
terminal.
"She faces the future with a realistic, yet
Roseanne Berger, M.D., associ- optimistic point of view. She's very calm
ate dean for graduate medical education.
and brave and even at times when she is
"Her name is Frieda Bair, and l remem- uncomfortable or in the hospital.
ber her for a number of reasons. She is an
"l have to feel her attitude is certainly
accomplished poet. She is an elegant, ar- contributing in a lot of ways to the way she
ticulate, very attractive elderly woman is coping with a very serious illness .
who has a terminal disease ... rather, Even when she is in the hospital, she
cancer ... l don't want to say terminal, has the ability to reach out to other

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people
e v e n
though she
has a very good reason to be introspective
and self-centered. But despite all that she's
interested in and concerned with other
people. Whenever l see her, before l even
have a chance to say a word, she asks me
how I am. And it's not just me- she's like
that with other people.
"She's always been an observer of life.
She has these inspirations, or muses ...
"l first saw her about two years ago. She
was diagnosed with cancer [pancreatic]
that first visit. But her illness is only a small
part of this woman - her creativity and

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�11 -relegance are central to her.
"She has always been a teacher, formally, and she has allowed me to share her
story with fourth-year medical students,
so her case has been examined in detail by
several seminars of medical students and
she has been more than willing to allow
me to do that- and has always been very
gracious about allowing them to examine
her and ask her about what she was feeling
and what was happening with her life.
"Her poetry has given me an insight
into this person. She writes about very
tangible things that people can relate to
easily, like home. And she has a lovely
little poem about red mittens ... the Buffalo Blizzard ... pollution ... and this one
that I use for the medical students.
"She is very much at peace with herself,
and has that calm and confidence that
comes from having led a full life. She is at
ease and peaceful with what is happening.
She is ready to accept death if it happens,
but she's not just going to give up. She
wants to live every day as well as she can."

Ji first
sa\v her about
t\vo years ago.
She \vas
diagnosed \ vith
cancer
[pancreatic] that
first "risit. But
her illness is

Robert Milch, M.D., '68, medical
director of Hospice Buffalo.
"There are so many patients in my line
of work who are recollected for different
reasons. And it's good that we try to recollect as many as possible - each of them is
part of the fabric of us.
"I remember a patient with cancer of
the pancreas who was referred to us after
discharge from one of our teaching hospitals. His wife was given a prescription for
demerol and syringes to inject him with.
"And we were told that he was a
'troubled patient' because at the height of
one of his pain episodes, he bent the
siderails ofa bed. We got him offinjectables
to a more appropriate medication and he
lived a comfortable and pain-free life for
the remainder of his five months.
"His gratitude was matched only by
ours.
"I remember seeing patients who point

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out just how fallible all the things we
learned in medical school are regarding
the use of pain medication.
"I remembera39-year-old woman with
cancer of the pancreas. As her disease
progressed, she would take four grams of
morphine every four hours. Do you know
what the normal dose is?
"We brought her into the hospital and
gave her an epidural of morphine of just
four milligrams. And all her pain disappeared.
"We had to actually convince her to
take small amounts of morphine to prevent withdrawal.
"All the things we learned about addiction and dosing are not always applicable.
"I remember a young man of 28 who
was dying of Hodgkin's. Every day I
came in to see him he was wearing a
different t-shirt- whether it was U2,
Jefferson Airplane, The Who - he always had some t -shirt from a rock group.
As he got thinner and thinner, one day
he was wearing one that said 'Hoots and
the Geraltones.' So I said, 'Who are
these guys?'
"And he said, 'We got you!' He was
Hoots and his wife was Geraldine and they
just had one made up because they finally
ran out.
"I remember a man who was 50 and
dying of cancer of the thyroid. When he
and his wife had gotten married they had
been very poor together for a long time. By
dint of hard work, their marriage had
worked out successfully - their children
were healthy, they had sacrificed a lot in
their early years.
"The one thing she had wanted, but
never had got, was a pair of diamond
earrings. He was going to die before their
next anniversary, and did, in fact, die
about six months before.
"But on the day before that anniversary, he had delivered to her a pair of
diamond earrings."
+

only a small part
of this \voman
- her creativity
and elegance are
central to her. "

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�By

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Andrew

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o

There was a time when organized medicine didn't think
much of managed care. In fact, it tried desperately to stamp
out, or at least contain, the health maintenance organizations
that were spreadingfrom the west coast.
Managed care won.
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��ne in five insuredAmericans now
belongs to
an HMO .
At least half
the nation's
physicians are
believed to be affiliated with HMOs and related entities, and the majority at some point encounter utilization review, part of managed care's widening spectrum. The American Medical Association last year went so
far as to acknowledge the "legitimacy" of
HMOs. ow, organized medicine is even
getting into the game- the Medical Society of the State of ew York is forming a
statewide physician network to compete
on the managed care field as early as this
year.
Health care reform will only accelerate
the trend. While details remain to be hammered out in Congress, the Clinton
administration's reform plan relies heavily
on managed care to deliver health services. In New York State, Gov. Mario
Cuomo is also pushing a reform initiative
emphasizing managed care principles.
Once the dust settles, several trends are
obvious: greater demand for primary-care
physicians, the backbone of managed care
plans; a continued erosion of the solo
practice as more physicians are pushed
into groups, and further diminution of the

~~FOR THE

autonomy physicians have traditionally
enjoyed.
"For the individual physician, I think
it's a very disquieting time," said UB School
ofMedicine and Biomedical Sciences Dean
john aughton,M.D. "We'vehadthroughout the history of medicine in the United
States the fee-for-service system and the
solo practice. Clearly the forces are to
encourage physicians to practice more in
groups than in the past."
In 1980, 4 7 percent of ew York State
physicians were in solo practice. By 1988,
the latest year for which figures were
available, the percentage had dropped to
41 percent overall and to only 27 percent
of doctors under 40 years old.
Only 2 percent of New York doctors
listed HMOs as their primary practice in
1988. But many more are affiliated with
non-staff HMOs and similar plans, the
fastest-growing segment of the managed
care sector. o one knows exactly how
many, but nationally it's estimated to be at
least half of practicing physicians.
"In some communities, every doctor is
involved," said Kathryn Allen, executive
director of the New York State HMO Council.
And HMOs are scooping up more and
more patients. During the 1980s, national
HMO enrollment nearly quadrupled to 40
million. In ew York State it tripled and
now stands at about 3.5 million. Health
care reforms are expected to drive the

numbers up dramatically, though ew
York State Health Commissioner Mark
Chassin, M.D., said that if federal rules
permit, he favors a flexible approach based
on the needs and resources of different
regions of the state.
" etworksandhealthplansandHMOs
are part of the solution, but forcing consumers into one of the health plans, forcing physicians and hospitals into one of
the health plans is not what we want to
do," he said.
However reforms play out, there will
be greater emphasis on primary care physicians.
"It can't be successful unless there is a
larger pool of generalists available," said
UB's Naughton.
About one-third of the approximately
56,700 practicing doctors in New York are
in primary care. It's the same proportion
nationally, and the exact opposite of the
generalist-specialist ratio in most other
nations. Since managed care programs
rely on primary care physicians to coordinate and control patient treatment, it's
estimated that at least half of all physicians
should practice the primary care specialties to make the programs work effectively.
In ew York's inner cities and rural
areas, there aren't enough physicians now,
said Richard Kirsch, chairman of the ew
York State Health Care Campaign, a coalition of groups pushing reform. "The

INDIVIDUAL PHYSICIAN, I

THINK IT'S A VERY DISQUIETING
TIME."
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�said aughton. Last year UB, in consultation with its consortium of teaching hospitals, set a goal of getting half its residents
into primary care by 1995. However,
aughton noted, even if all the nation's
residency programs went to the 50 percent goal, the proportion of practicing
generalists wouldn't reach 50 percent until the year 2035.
In the meantime, some specialists might
find themselves in the same boat as the
laid-off factory worker.
"People for the first time in recent
months have been talking about the issue
of retraining," said Edward Salsberg, director of the ew York State Department
of Health's Bureau of Health Resources
Development. "If you have a large supply
of specialists and managed care comes
into place and the use of specialists is
decreased, then the demand and need for
specialists should be dropping. In a specialist-rich state like New York, there's the
question of what they will do. "
Psychiatrists are already feeling the
managed care crunch. Faced with premium complaints from employers, the
Blue Cross and Blue Shield HMO in Buffalo , Community Blue, last year hired an
outside health management company to
oversee its mental health-substance abuse
benefits. The company revised Community Blue's provider list, cutting the number of psychiatrists from 99 to 31. lt also
reduced the number of Ph.D. psychologists from 141 to 93. The number of
master's-level psychologists, social workers, psychiatric nurses and addiction counselors rose from 94 to 166.
"They cover a broader range and there
is not as heavy a concentration of psychiatrists," said Lynn Sidare, Community Blue
spokeswoman. "We felt there were other
specialties in mental health that could
provide good, effective treatment."
She said anyone who was seeing a
psychiatrist removed from the list was
given a grace period to wrap up treatment

main thing New York needs to be doing is
building up its capacity to provide primary care to its citizens," he said.
Cuomo's initiative acknowledges that
-proposing incentives to steer more
medical students to primary care
and financial help to open primary care practices.
"l think we're a
school that has been
looking at the problem for quite
some time, "

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�and make the switch.
"The medical community obviously
thinks this is very wrong," said H. John
Rubinstein, M.D., president of the Medical Society of the County of Erie and a
1966 UB medical graduate. The society
protested to the state, which ruled that
Community Blue was within its rights.
The tate, in fact, did the same thing
last year with its own insurance plan,
farming out management ofmental healthsubstance abuse benefits for 395,000 state
and local government employees. "On an
annualized basis, the program has saved
us $30 million," said Priscilla Feinberg of
the governor's Office of Employee Relations.
any physicians are
frustrated
and angry,
feeling that
while the
profession
bears some responsibility, they've been
made the scapegoat for a health care system that is far too expensive and far too
inequitable. They agree that some kind of
change is needed, but worry about the
details.
"My fear is we'll be left with even more
administration and more micromanagement than we have now," said Amy P.
Early, M.D., an associate clinical professor
in UB's oncology division.
The Medical Society of the State of ew
York is hoping to maintain more control
for physicians by taking a lesson from the
labor movement and organizing, not as a
union, but as a network of doctors who
can negotiate from a position of strength
in the expanding world of managed care.
"Like it or not, the pressures faced by
private practicing physicians in their efforts to compete effectively in the health
care arena will be overwhelming and many
physicians will lose the struggle to main-

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tain their private practices," ancy H.
Nielsen, M.D., SU Ytrusteeand the plan's
coordinator, wrote in a report to the medical society's house of delegates this year.
"When these challenges are added to the
growing problems of a crushing bureaucracy and significantly decreased payments, it is evident that for the physicians
of ew York State, 'business as usual' is no
longer possible."
The MSSNY Physician Network would
provide medical services for insurers,
employers and HMOs, with the state medical society negotiating statewide contracts
and local medical societies handling local
contracts. The network, which would have
its own utilization review and quality assurance programs, would require an unspecified financial commitment from
members.
"It is clear that if these initiatives are
uniformly implemented, physicians will
gain immeasurably in their ability to compete effectively in the future managed care
market," ielsen wrote.
The medical society is also fonning a
second network to compete in New York's
Medicaid Managed Care Program, which
seeks to get half the state Medicaid population into managed care by 1996.
By and large, physicians have come to
accept HMOs and managed care arrangements as part of the health care landscape.
Early, an oncologist with the Buffalo Medical Group, said she has had occasional
problems getting HMO approval for specialized cancer treatments in facilities outside the area. But overall, she feels she has
a good relationship with her group's HMOs.
"If I, as the primary doctor, have a problem
or recognize that my patient has a special
need, I can call someone," she said. "I may
not always get approval, but I have a line
of communication open."
The real hassles, she said, are with the
long-distance utilization reviewers. "For
me to call an 800 number to someone in
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clue about to seek hospital admission for
my desperately ill patient is ludicrous,"
she said.
Chassin, who was most recently senior
vice president of a utilization review company before becoming New York's health
commissioner, agreed that there is both
good and bad under the managed care
umbrella.
"In its best incarnation it can be a very
effective way to maintain quality or improve quality at the same time costs are
being controlled," he said. "But it's not
always implemented that way. In other
implementations it is micromanagement
and throwing obstacles in the way of physicians trying to provide quality care for
their patients."
Chassin favors a flexible approach to
reform in ew York, one that allows a
variety of arrangements for health care
delivery and compensation. He wants the
state's rate-setting power expanded to
physicians so there will be more uniformity and fewer inequities, like Medicaid
reimbursements that discourage doctors
from serving poor neighborhoods. But he
would like different cities and regions to
use the payment system that works best
for them, whether it be salary, capitation
or fee-for-service. "We want to have a
statewide approach that encourages diversity," he said.
John Rodat, an Albany health care consultant who has served in a variety of state
positions, said perhaps the biggest trick in
reform will be finding a way to accommodate the organizational impulses of the
reformers and the independent nature of
medicine.
"The knowledge and skills and temperament and perspective that good physicians can and should have are ones which
cause them to focus totally on the individual patient and not to see the organizational context around them," Rodat said.
"These are not folks in gray flannel suits,
and they should not be."

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�But those traits, he said, have made the
medical community slow to deal with
restructuring, to see it as someone else's
problem.
"My very strong fear is that those who
are going to impose reform, because they've

B y
nan age when care is "managed"
and physicians are "providers,"
everyone complains about the
bureaucracy. But to Robert A.
Milch, M.D., it was something a
little more unsettling. It was the
feeling that medicine was surrendering its humanity to a cold
ethic of efficiency.
He wanted out.
Unlike many frustrated physicians, the
1968 UB medical graduate didn't retire
early. But he did give up his surgical
practice to become medical director of
Hospice Buffalo on january l. He's much
happier now.
"What I found was, I think, a microcosm of the best that medicine has to offer,
which is humane, appropriate, cost-effective care," Milch said.
It's unclear how many physicians are
fed up and making a change. "At this point
it's still primarily anecdotal," said Edward
Salsberg, director of the ew York State
Department of Health's Bureau of Health
Resources Development. In 1990, the latest year for which figures were available,
only 52,722 of ew York's 70,080 licensed
physicians were active in patient care, but

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make things worse for many folks .... To
do it right, it seems to me we have to have
some kind of common language for solving the problem."
Will that happen?
"I think it's possible," he said.
+

grown impatient and the public has grown
impatient, have a completely different set
of perspectives," he added. "Even though
they also may be perfectly wellintentioned, it is my great fear that their
organizational perspectives are going to

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to specialized treatment.
"What a terrible word," Rodat said.
"What's terrible about it is that it is, in fact,
descriptive of what the role is.. .. This is
somebody whose primary role is to decide
whether or not you go on, and if so, what
price you pay. Wait a minute! "
For Milch it was seemingly small things
that added up. Like the surgery schedules
that left residents little time to interact
with patients, to gain some understanding
of their hopes and fears before the anesthesiologist arrived. "This system conspires against humanity in the name of
perceived efficiency," he said.
He blames insurance companies. But
he also blames medicine itself. "You've got
to recognize truth when it's staring you in
the eye," he said. "We have so many
problems with health care delivery. So
many of them are societal and the practitioner is the convenient whipping boy.
But so mu.c h of the criticism is well-deserved. We have abdicated so many of our
responsibilities. We have closed our eyes
to questionable practices. Once you lose
your deserved stance of moral rectitude,
you can't be surprised when those who
you should be serving tum on you." +

the proportion doesn't seem notably different from past years, Salsberg said.
Still, everyone seems to know someone
who couldn't take it anymore. "I have seen
some people who have just gotten out of
practice and taken administrative jobs
because the bureaucratic morass has gotten so bad," said H. john Rubinstein,
president of the Erie County medical society.
"I think it's fair to say that practicing
medicine is probably not as much fun as it
once was, when there wasn't a lot of regulation," said john aughton, M.D., UB
medical school dean. "I think most physicians are very well motivated and committed to providing good care and dedicated
to the needs of patients. But the emphasis
on more external review and documentation of what we do, those are hard habits
to take on. It does create a climate of
distrust between physicians and patients,
and vice versa. "
john Rodat, a health care consultant in
Albany, thinks the lexicon of contemporary health care tells a lot about it. Take,
for instance, "gatekeeper," the term managed care plans use for primary care physicians, who control their patients' access

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········· · ··················· · · ····· · ·· ··············· ·· ·· ·· ····· · ·· · ··· · · · ····· ·· ·· · · ··· ···· ···

~
I

tiative.
"In addition to benefiting women living in Western ew York," he said, "this
program will accelerate the role of the
school's Department of Social and Preventive Medicine in epidemiology, preventive
medicine and community medicine. Italso
will complement the medical school's efforts to train a larger number of primary
care providers."
The UB Women's Health Initiative will
be headquartered in Farber Hall on the UB
South Campus. A 24-hour hot line will be
established later this summer to answer
questions about the study and to take the
names of women who wish to participate.
Trevisan said he is convinced that one
of the major reasons UB was selected to
participate in the study is because the

UB selected as vanguard center for
national Women's Health Initiative

Maurizio Trevisan, M.D ., chair of sohe University at Buffalo has been
selected to be a lead research center cial and preventive medicine, is UB's primary investigator.
in the $635 million Women's Health
"This is a wonderful occasion for UB
Initiative- the largest clinical trial
and Western ew York," Trevisan said.
ever undertaken in the United States.
"This was a very tough competition and
UB will aetas one of 16 vanguard
clinical centers; its share of the project will UB fared very well. "
john P. aughton, UB vice president
total about $11 million over 12 years.
The Women's Health Initiative is being for clinical affairs and dean of the medical
undertaken to learn how to reduce the risk school, said, "UB is very pleased to be
of coronary heart disease , breast and among the institutions selected to be vancolo rectal cancers and osteoporosis in older guard centers in the Women's Health Iniwomen. Approximately 160 ,000
postmenopausal
women between
the ages of 50 and
79 will be recruited
by the 45 research
centers throughout
the country participating in the study.
A pproxi rna tel y
3,500 women will
be recruited from
Western ewYork.
As a vanguard
center, UB will help
design the study
and establish operating procedures
that other centers
will follow . Clinical trials are expected to begin at
the vanguard centers this fall. The
remaining
39
clinical centers are
expected to be anJean Wactawski-Wende, M.D., dinical assistant prafessar of Gynecology and Obstetrics, and Maurizio Trevisan, M.D., chair of
nounced this fall.
Social and Preventive Medicine, at a news conference announcing UB' s vanguard center designation.

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entire community supports the effort.
Ph.D. , and Terry Pechacek, Ph.D., all from
"We were able to offer a package not the UB Department of Social and Prevenmany institutions could match," he said. tive Medicine.
"This effort involved the departments of
Also participating are Myroslaw
gynecology and obstetrics, medicine and Hreshchyshyn, M.D., chair, and jean
medical technology. We had the support Wactawski-Wende, M.D., from the Deof the deans of the medical school and the partment of Gynecology and Obstetrics;
School of Health Related Professions and Robert Kohn, M.D., Susan Graham, M.D.,
the UB provost. We had the support of the June Chang, M.D. and Paresh Dandona,
medical community, the political commu- M.D., from the Department of Medicine,
nity, the health-care providers and civic and Donald Armstrong, Ed. D., chair of the
and religious organizations.
Department of Medical Technology. +
"This is a very complex study, involvB
Y
LOIS
B
AKER
ing recruiting volunteers, retaining them
and arranging for reimbursement,"
Trevisan said. "Because everyone was behind us, we were able to address all of these
issues."
The study itself will be conducted in
two parts - clinical and observational.
he United State's first comprehenThe clinical component will involve three
sive
training center for nuclear iminvestigations:
aging
has been established
• A test of the effectiveness of hormone
at the Univerreplacement therapy in reducing the risk
sity at Buffalo,
of coronary heart disease, osteoporosis
funded by a
and endometrial cancer.
• A study of the effect of a low-fat diet $450,000, three-year
on the risk of cardiovascular disease and grant from Siemens
H.G.
breast and colorectal cancer.
The grant is the re• An investigation of the effectiveness
of calcium and vitamin D supplements in sult of two years of
reducing osteoporosis, colorectal cancer, discussions between
UB and Siemens, an
blood pressure and breast cancer.
The trials will begin in August or Sep- international contember in Western New York. The obser- glomerate headquarvational study will follow about 2,200 tered in Germany and a
women from 12 to 17 years of age to try to major supplier of
determine physiological and lifestyle fac- nuclear imaging equiptors that can affect the health of women. ment worldwide.
Under the grant,
Participants in this phase initially will give
detailed medical histories and then will be the training center- to be headquartered
contacted every three years to update their in the medical school's department of
nuclear medicine- will concentrate on
information.
Co-principal investigator on the study positron emission tomography (PET).
"We're in the process of organizing a
is james Marshall, Ph.D., UB professor of
core
curriculum to train everyone from
social and preventive medicine.
Otherinvestigatorsarejo Freudenheim, the PET technician who assists the chemPh.D.; Alma Blake, Ph.D.; Diane Hayes, ists, through all of the higher levels of

science right up to a director of PET operations," said joseph A. Prezio, M.D., UB
chair of nuclear medicine. " o one is
doing that anywhere in the United States. "
Siemens needed a center that could
train its people in depth in this new field,
Prezio said, and UB already had a wellregarded program in nuclear medicine
and is establishing a major PET facility in
conjunction with the Buffalo VA Medical
Center. The new facility will be one of the
most advanced PET imaging centers in the
world.
'The problem throughout the U.S. and,
probably the world, is that training for
PET has not been organized appropriately, or in enough depth, so that you can
send someone to one site and have them
come back seasoned and trained," Prezio
said. "Siemens liked what we were doing
here. They were looking for someone willing to put the effort into it.
"Our goal from the beginning,"
he added, "in addition

UB establishes comprehensive
nuclear imaging training center

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valed in the United
States," Preziostated.
The center will be
organized around four
major training groups
-technicians, radiochemists, nuclear
physicists and physicians, according to
Prezio. Training of
PET technicians began this spring. Other
programs will accept enrollees when curriculums are finalized. Training periods
will vary from a month for technicians to
two years for physicians being trained to
+
interpret PET images.
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Maurizio Trevisan is poised to expand
SPM's role in both scope and breadth
he first thing that struck Maurizio
Trevisan, M.D. about this country
after he came here from his native
aples, Italy, was Americans' penchant for eating large breakfasts
with meat every day.
"My parents used to have a cup of
coffee- maybe toast and jelly- but no
meat," he recalls.
ow, the chair ofUB's Department of
Social and Preventive Medicine (SPM) is
putting that observation - and many
more about the American lifestyle - to
work, studying dietary habits with an eye
toward reducing the incidence of the number one and two killers of Americans,
cardiovascular disease and cancer.
Trevisan believes that the key to changing the bad habits that contribute to the
deaths of over 1.2 million Americans each
year is "to focus more on societal problems. The largest impact will come not so
much from focusing on the individual,
but by influencing the market for foodby lowering fat, eating leaner meats.
"And the market," he notes, "has responded to consumer demand. The largest impact will be the change in labeling,"
soon to be phased in by the Food and
Drug Administration.
"Increased awareness has created a
change in consumer awareness that has
resulted in producers changing their packaging."
Trevisan, who originally came to this
country in 1979 to study at orthwestern
University, talks about his former boss in
Chicago, a leading authority on diet and
heart disease. "He shows slides of two
meat cows - one from years ago and one
from now. There is a huge difference in

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the sizes. And now the one that wins the
competitions is leaner. People used to
look for the steak with all the marbling.
ow they're looking for the leaner meat.
"We tend to consume what's available," he notes, adding, "I was lucky
enough to grow up in a place where you
didn't use butter on your bread and you
didn't eat meat every day. We would only
eat meat once a week.
"Lunch was the major meal, and always with pasta. I'm still not used to a cold
lunch," even after eight years.
In 1982, Trevisan returned to the University of aples, where he obtained his
medical degree, before coming to UB as an
assistant professor in 1985.
He notes that since he's lived in the
United States, "dietary habits have changed
tremendously," resulting in decreased incidence since 1970 in heart disease and
stroke. "And they're still changing for the
better."
And that is his ultimate goal, of course
- to be able to influence peoples' habits
and lifestyles to improve the quality of
their lives.
To that end, Trevisan and Social and
Preventive Medicine are carrying on the

work of Saxon Graham, emeritus professor and former chair of the department.
Graham and his groundbreaking work
in epidemiology and diet and disease were
key to Trevisan's decision to come to UB.
He was, at the time, being wooed by two
other institutions.
"One of the reasons I came here," he
recalls, "was I fell in love with Saxon
Graham. I thought he had tremendous
vision for the department.
'Td like to continue what Saxon started.
I want to maintain and continue to
strengthen the department in the field of
diet and chronic disease. And I'd like to
expand it and continue to include environmental and occupational research. "
Another ofTrevisan's goals is to make
SPM more clinical. "My background," he
explains, "is in internal medicine.
Trevisan moved closer to this goal last
March when UB was named a vanguard
center in the ationalinstitutes' ofHealth
landmark Women's Health Initiative.
UB, under the auspices of SPM, along
with the Departments of Obstetrics and
Gynecology and Medicine, will look at a
number of factors affecting women's
health. Among those to be investigated in
the observational study that will look at
over 100,000 postmenopausal women are
diet, physical activity, smoking, estrogen
replacement therapy, alcohol use and
psychosocial factors, including social networks, personality, depression and role
satisfaction.

"At some time, I'd like to expand our definition of
Social and Preventive Medicine by being more closely
in contact with the community I don't want to be an
Ivory Tower scientist. We need to participate more and
be more aware of the needs of the community"
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Maurizio Trevisan, M.D.
UB will also participate in the initiative's
clinical trials to determine whether ERT
for postmenopausal women is ultimately
beneficial or not. [See the previous story in
this section for more information on the
Women's Health Initiative.]
Trevisan acknowledges the chairs of
the other departments involved for their
support and involvement in obtaining the
prestigious IH designation, as well as
that of john Naughton, M.D., vice president for clinical affairs and dean of the
School of Medicine and Biomedical Sciences.
"The IH people said, 'It's the first time
we've ever seen a dean so involved.' If we

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his department is relatively small, it is
thriving under the medical school's primary care recruitment and women's health
initiatives and poised to enjoy an even
larger role in the future.
"At some time, I'd like to expand our
definition of Social and Preventive Medicine by being more closely in contact with
the community. The medical school has a
responsibility for the health of its community.
"I don't want to be an Ivory Tower
scientist. We need to participate more and
be more aware of the needs of the community."
+

make it, it's a great end to the efforts of
many people involved," Trevisan said,
referring to one of the IH's last site visits
before awarding the vanguard clinical center designation to UB.
Naughton has similar praise for
Trevisan. "Maurizio is a very broad thinker.
He is committed to epidemiologic and
clinical research, and is a good leader of
the faculty. His strong leadership, particularly in the area of primary care and interaction with other departments, make us
fortunate to have him here."
Trevisan officially took over SPM on
january l after serving as interim chair
after Saxon Graham retired. And although

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I

Suraj A. Acharya
Family Practice, UniversityofCalifornia-San Diego
Medical Center, San Diego, California

Match Day '93 aresounding success for
UB'sgraduating medical students

Shabi na Ahmad
Gynecology/Obstetrics, University at Buffalo
Graduate Medical/Dental Consortium, Buffalo, ew
York

atch Day went well for UB's medical students this
year- with 84 percent of the graduating seniors
accepted into one of their top three residency program choices.
Dennis Nadler, M.D., associate deanfor curricular and
academic affairs, said that this year saw 63 percent of
UB's medical students accepted by their first choice of
residency programs, 11 percent by their second choice
and 10 percent by their third choice.
In the highly competitive surgical specialties, 10 of 11
UB students who applied were accepted. "The usual
match in these specialties is 50 percent," Nadler said. "So
to get 10 out of 11 is excellent."
Nearly one-third of the students will remain in Buffalo
to continue their training- an increase of7 percent over
last year. Twenty percent will go to other New York State
programs, while about half were matched with out-ofFollowing is a list of the medical school's Class of '93
matches.
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ancy A. Allen
Gynecology/Obstetrics, University at Buffalo
Graduate Medical/Dental Consortium, Buffalo, ew
York
Jewel D. Alleyne
Surgery, University at Buffalo Graduate Medical/
Dental Consortium, Buffalo, ew York
Matthew E. Alter
Surgery, University at Buffalo Graduate Medical/
Dental Consortium, Buffalo, ew Yorlz
Pavan Anand
Anesthesiology, Albany Medical Center, Albany,
ew York
Gregory A. Andrews
Obstetrics/Gynecology, Sisters ofCharity Hospital,
Buffalo, ew York
Michael]. Aronica
Med!Peds, University at Buffalo Graduate Medical/
Dental Consortium, Buffalo, ew York
Behnam Asgharian
Surgery (Prelim), University of Louisville,
Louisville, KentucJzy
Hisla A. Bates
Intemal Medicine (Primary), Yale-New Haven
Hospital, ew Haven, Connecticut
Ophthalmology, Yale University, ew Haven,
Connecticut
Andrew J. Bauer
Pediatrics, Madigan Army Medical Center, Tacoma,
Washington
Elyssa A. Blissenbach
Intemal Medicine, Medical University of South
Carolina, Charleston, South Carolina
John S. Brebbia
Surgery, University at Buffalo Graduate Medical!
Dental Consortium, Buffalo, ew York

state residency programs.

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Elizabeth A. Allen
Gynecology/Obstetrics, University at Buffalo
Graduate Medical/Dental Consortium, Buffalo, ew
York

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Jon M. Bruce
Surgery, University at Buffalo Graduate Medical!
Dental Consortium, Buffalo, ew York

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AnneM. Comi
Pediatrics, University at Buffalo Graduate MedicaV
Dental Consortium, Buffalo, New York
Thomas A. Coppola
Internal Medicine, University at Buffalo Graduate
MedicaVDental Consortium, Buffalo, New York
Andrew C. Corsello
Internal Medicine, Strong Memorial Hospital,
Rochester, New York
Vanessa L. Crothers
Obstetrics/Gynecology, Ohio State University
Hospitals, Columbus, Ohio
Joan C. Davis
Obstetrics/Gynecology, Baystate Medical Center,
Springfield, Massachusetts
Michael L. DuBartell
Family Practice, Middlesex Hospital, Middletown,
Connecticut
Karen M. Duguid
Obstetrics/Gynecology, Strong Memorial Hospital,
Rochester, ew York
John A. Dzik
Pediatrics, University at Buffalo Graduate MedicaV
Dental Consortium, Buffalo, New York

Congratulations abound as over 60 percent of the
class members are accepted into their top choice.

Tricia L. Eisenstein
Surgery (Prelim), Mt. Sinai Hospital, New York,

ew York
Julene 0. Evansmurage
Obstetrics/Gynecology, Maimonides Medical
Center, ew York, New York

Lisa A. Cardamone
Surgery (Prelim), University at Buffalo Graduate

ALL

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TONG

Thomas G. Burke
Internal Medicine (Prelim), St. joseph Hospital,
Denver, Colorado
Emergency Medicine, Denver General Hospital,
Denver, Colorado
Craig]. Burrows
Family Practice, St. Vincent Health Center, Erie,
Pennsylvania
Heather R. Campbell
Pediatrics, Children's Hospital of Philadelphia,
Philadelphia, Pennsylvania
Jean M. Cange
Family Medicine, University at Buffalo Graduate
MedicaVDental Consortium, Buffalo, ew York
Rodney Capiro
Obstetrics/Gynecology, Harlem Hospital, ew York,
New York

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MedicaVDental Consortium, Buffalo, ew York
Orthopaedic Surgery, University at Buffalo
Graduate MedicaVDental Consortium, Buffalo, ew
York

Gil M. Farkash
Obstetrics/Gynecology, University at Buffalo
Graduate MedicaVDental Consortium, Buffalo, ew
York

Richard M. Chemelli
Pediatrics, University at Buffalo Graduate MedicaV
Dental Consortium, Buffalo, New York

Paul Favorito
Surgery (Prelim), UniversityofMinnesota Hospital
and Clinic, Minneapolis, Minnesota

Elaine H. Cheon
Obstetrics/Gynecology, Strong Memorial Hospital,
Rochester, ew Yorl1

Ilana L. Feinerman
Otolaryngology, Tufts ew England Medical
Center, Boston, Massachusetts

William F. Chlosta
Surgery, St. Mary's Hospital, Waterbury ,

Michael S. Ferguson
Emergency Medicine, University of Massachusetts
Coordinated Programs, Worcester, Massachusetts

Connecticut
Josephine Cho
Internal Medicine (Prelim), Staten Island University
Hospital, New York, New York
Radiology - Diagnostic, Einstein Affiliated
Hospital, ew York, New York

David M. Fisher
Surgery, University at Buffalo Graduate MedicaV

Dental Consortium, Buffalo, ew York
David K. Frey
Psychiatry, SUNY Health Science Center at
Syracuse, Syracuse, ew York

Judine C. Coggins
Obstetrics/Gynecology, Sisters ofCharity Hospital,
Buffalo, ew York

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Allen Friedland
Med!Peds, University of Cincinnati Hospital,
Cincinnati, Ohio

Timothy D. Haley
Surgery, Medical College of Pennsylvania,
Philadelphia, Pennsylvania

Wallace E. Johnson
Internal Medicine, Strong Memorial Hospital,
Rochester, ew York

Myron L. Glick
Family Practice, Lancaster General Hospital,
Lancaster, Pennsylvania

John D. Hall
Obstetrics/Gynecology, University at Buffalo
Graduate Medical/Dental Consortium, Buffalo, New
York

Saidat T. Kashimawo
Psychiatry, Beth Israel Medical Center, New Yorh,
ew Yorh

Charles R. Gray
Psycl1iatry, Thomas jefferson
Philadelphia, Pennsylvania

Hospital ,

Betty B. Gregoire
Psychiatry, University at Buffalo Graduate Medical!
Dental Consortium, Buffalo, ew York
Kathleen T. Grimm
Med!Peds, University at Buffalo Graduate Medical!
Dental Consortium, Buffalo, New York

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Richard E. Hall
Surgery (Prelim), University at Buffalo Graduate
Medical/Dental Consortium, Buffalo, ew York
Honora M. Heffner
Patholog,, University of Minnesota Hospital and
Clinic, Minneapolis, Minnesota
James M. lsemia
Internal Medicine, Healtheast Teaching Hospital,
Allen10wn, Pennsylvania

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Robin M. Kass
Internal Medicine (Prelim), Faulhner Hospital,
Boswn, Massachuseus
eurology, Columbia University, New York, ew
York
Lisa F. Keicher
Pediatrics, Hershey, Pennsylvania State, Hershey,
Pennsylvania
Kevin J. Kelleher
Family Practice, Franklin Square Hospital,
Baltimore, Maryland

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Theodore J. Kolias
Internal Medicine, Hershey, Pennsylvania State,
Hershey, Pennsylvania
Joseph M. Kowalski
Surge1y (Prelim), University at Buffalo Graduate
MedicaUDental Consortium, Buffalo, New York
Paul M. Kozlowski
Surgery (Prelim), Strong Memorial Hospital,
Rochester, New Yorlz
Urology, Strong Memorial Hospital ofthe University
of Rochester, Rochester, ew York

UB' s graduating medical students getting the
good news: 84 percent were accepted into one of
their top three choices for residency programs in
this year's Match Day.

Brian J. Krabak
Internal Medicine (Prelim), Sinai Hospital,
Baltimore, Maryland
Physical Medicine and Rehabilitation, New England
Medical Center, Boston, Massachusetts

Jonathan R. Kemp
Internal Medicine (Prelim), University at Buffalo
Graduate MedicaUDental Consortium, Buffalo, ew
York
Ophthalmology, Louisiana State University Eye
Center, ew Orleans, Louisiana

J . Christopher Kuhn
Pediatrics, University at Buffalo Graduate MedicaU
Dental Consortium, Buffalo, New Yorlz

Cathy Kim
Surgery (Prelim), Barnes Hospital, St. Louis,
Missouri
Urology, Washington University, St. Louis, Missouri

Tracy]. Lathrop
Internal Medicine (Prelim), Einstein Affiliated
Hospitals, New York, ew Yorlz

Elizabeth H. Kim
Internal Medicine (Preli m), St. Vincent's Hospital,
ew Yorlz, ew York
Anesthesiology, Brigham and Women's Hospital,
Boston, Massachusetts

David]. Lee
Transitional Year, Presbyterian/St. Luke's Medical
Center, Denver, Colorado
Anesthesiology, Dartmouth-Hitchcoclz, Lebanon,
New Hampshire

Jeffrey 5. Kingsbury
Surgery (Prelim), University at Buffalo Graduate
MedicaUDental Consortium, Buffalo, ew York

Kewjung Lee
Family Practice, orthwestern University/St. joseph
Hospital, Chicago, Illinois

Ricardo A. Knight
Physical Medicine and Rehabilitation, Temple
University Hospital, Philadelphia, Pennsylvania

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Charles H. Lieu
Internal Medicine, Barnes Hospital, St. Louis,
Missouri

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.................... .... .... ...... .......... .....

An ebullient Jon
Brute reteives
tongratulations
from his
tolleagues.

Jeffrey R. Parnell
Internal Medicine (Primary), University at Buffalo
Graduate Medical/Dental Consortium, Buffalo, ew
Yorh
Ophthalmology, University of California-Los
Angeles, Los Angeles, California
Vikram . Patel
Surgery (Prelim), McGaw Medical Center,
orthwestern University, Chicago, Illinois
Otolaryngology, orthwestern University, Chicago,
Illinois

Francis R. Pallerson
Orthopaedic Surgery, SUNY Health Science Center
at Syracuse, Syracuse, ew York
Kristen L. Paulus
Internal Medicine, Georgetown University Hospital,
Washington, D.C.

Randall J. Loftus
uclear Medicine, University at Buffalo Graduate
MedicaVDental Consortium, Buffalo, ew York

Andrew C. Michel
Emergency Medicine, Geisinger Medical Center,
Danville, Pennsylvania

Karen M. Maier
Family Practice, Harrisburg Hospital, Harrisburg,
Pennsylvania

Rogena L. Miller
Pediatrics, Emory University School of Medicine,
Atlanta, Georgia

James K. Mantone
Orthopaedic Surgery, Grace Hospital, Detroit,
Michigan

David A. Milling
Internal Medicine, University at Buffalo Graduate
MedicaVDental Consortittm, Buffalo, ew York

Gina M. Marrero
Pediatrics, Yale- ew Haven Hospital, ew Haven,
Connecticut

Lomelle B. Mills
Internal Medicine, George Washington University,
Washington, D.C.

Bruce B. Marshall
Emergency Medicine, Carolinas Medical Center,
Charlotte, orth Carolina

Daniel]. Mollin
Internal Medicine, University of orth Carolina,
Chapel Hill, orth Carolina

Christina L. Master
Pediatrics, Children's Hospital , Philadelphia,
Pennsylvania

Michael]. a ugh ton
Internal Medicine, Barnes Hospital, St. Louis,

Edward F. Math
Internal Medicine (Prelim), University of
California-Irvine, Irvine, California
Radiology-Diagnostic, Duke University Medical
Center, Durham, orth Carolina

Jennifer A. ordby
Pediatrics, University at Buffalo Graduate MedicaV
Dental Consortium, Buffalo, ew York

Fiona A. McConnell
Pediatrics, University of Colorado, School of
Medicine, Denver, Colorado
Kevin C. McMahon
Family Practice, St. Vincent Health Center, Erie,
Pennsylvania
Claudia F. Michalek
Psychiatry, University at Buffalo Graduate MedicaV
Dental Cons01iium, Buffalo, ew York

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Katherine A. O'Donnell
Surgery, University at Buffalo Graduate MedicaV
Dental Consortium, Buffalo, ew York
Sanjay R. Ogra
Internal Medicine (Primary), University at Buffalo
Graduate MedicaVDental Consortium, Buffalo, ew
Yorh
William E. Ottowitz
Internal Medicine (Prelim), University at Buffalo
Graduate Medical/Dental Consortium, Buffalo, New
York

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Laura]. Pierce
Med!Peds, Strong Memorial Hospital, Rochester,
ew York
James D. Pile
Obstetrics/Gynecology, University at Buffalo
Graduate Medical/Dental Consortium, Buffalo, ew
Yorh
Michael D. Rabice
Pediatrics, University at Buffalo Graduate MedicaV
Dental Consortium, Buffalo, New York
Arlene E. Ricardo
Surgery, University of Texas Medical School,
Houston, Texas
Gloria Richards
Internal Medicine C., Georgia Baptist Medical
Center, Atlanta, Georgia
Marcus R. Romanowski
Surgery (Prelim), University at Buffalo Graduate
MedicaVDental Consortium, Buffalo, New Yorh
Orthopaedic Surgery, University at Buffalo
Graduate Medical/Dental Consortium, Buffalo, ew
York
Leon Ronen
Family Practice, aval Hospital Charleston,
Charleston, South Carolina
Paul B. Rosenthal
Family Practice, UniversityofCalifornia-San Diego
Medical Center, San Diego, California
Mark A. Runfola
Surgery, Good Samaritan Regional Medical Center,
Phoenix, Arizona
Richard S. Safeer
Family Practice, Franklin Square Hospital Center,
Baltimore, Maryland

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Diane M. Sanfilippo
Obstetrics/Gynecology, University at Buffalo
Graduate Medical/Dental Consortium, Buffalo, New
York
Frank M. Scappaticci
Internal Medicine, Hospital of the University of
Pennsylvania, Philadelphia, Pennsylvania
Eric]. Schneider
Family Practice, University of VirginiaCharlottesville, Charlottesville, Virginia

Jeffrey A. Senall
Orthopaedic Surgery, Henry Ford Hospital, Detroit,
Michigan
Jeffrey Seymour
Surgery (Prelim), University at Buffalo Graduate
Medical/Dental Consortium, Buffalo, New York
Peter U. Shen
Internal Medicine, The
York, ew York

1

ew Yorh Hospital,

ew

Andrew L. Sherman
Physical Medicine and Rehabilitation, University
of Washington Affiliated Hospitals, Seattle,
Washington

Julie M. Sicilia
Transitional Year, Mary Imogene Bassett Hospital,
Cooperstown, New York

Patricia Sticca
Pediatrics, University at Buffalo Graduate Medical!
Dental Consortium, Buffalo, 1 ew York

Michel E. Wild
Obstetrics/Gynecology, ew Yorh Downtown
Hospital, ew Yorh, ew Yorh

Michael F. Sweeney
Obstetrics/Gynecology, Akron City Hospital, Akron,
Ohio

Kelly A. Wood
Internal Medicine, Barnes Hospital, St. Louis,
Missouri

Brian Szymanski
Physical Medicine and Rehabilitation, University
at Buffalo Graduate Medical/Dental Consortium,
Buffalo, New York

Thomas]. Yacovella
Medicine C, University of Minnesota Hospital and

avy

+

Clinic, Minneapolis, Minnesota

aval

Heather Campbell phones home.

Courtenay C. Watt
Emergency Medicine, Allegheny General Hospital,
Pittsburgh, Pennsylvania

Samiris Sostre
Psychiatry, Einstein Affiliated Hospitals, ew York,
ew York

Michelle A. Webb
Internal Medicine, Medical College of Virginia,
Richmond, Virginia

Anthony M. Spina
Surgery (Prelim), University at Buffalo Graduate
Medical/Dental Consortium, Buffalo, New York

h

Edward R. Stephenson
Surgery, Hershey, Pennsylvania State, Philadelphia,
Pennsylvania

Christopher R. White
Internal Medicine (Prelim), Sisters of Charity
Hospital, Buffalo, New Yorl1
Radiology-Diagnostic, University Health Center
of Pittsburgh, Pittsburgh, Pennsylvania

Anil K. Vaidian
Internal Medicine, Montefiore Medical Center,
Bronx, ew York

Michael K Soeder
Med!Peds, Baystate Medical Center, Springfield,
Massachusetts

p

Thomas C. Wheatley
Pediatrics, University Hospital of Cleveland,
Cleveland, Ohio

Mary C. Totten
Otolaryngology, Loyola University, Chicago,
Illinois

Christina A. Smith
Psychiatry, University Health CenterofPittsburgh,
Pittsburgh, Pennsylvania

0

Judy A. Wesolowski
Obstetrics/Gynecology, SU Y Health Science
Center at Syracuse, Syracuse, ew Yorh

Kristine L. Tenebruso
Internal Medicine (Primary), Rhode Island Hospital,
Providence, Rhode Island

Gail H. Smallen
Pediatrics, University at Buffalo Graduate Medical!
Dental Consortium, Buffalo, ew York

a

icho\as A. Stathopoulos
Internal Medicine (Prelim), St. Mary's Hospital,
Rochester, ew York
Ophthalmology, Pennsylvania State University,
Hershey, Pennsylvania

Guy A. Taylor
Internal Medicine (Prelim), University at Buffalo
Graduate Medical/Dental Consortium, Buffalo, ew
York
Anesthesiology, Presbyterian Hospital, New York,
New Yorh

Alissa M. Shulman
Surgery, University of Texas Medical School,
Houston, Texas

u

Jonathan I. Weinstein
Pediatrics, Children's Hospital National Medical
Center, Washington, D.C.

Robert W . Tahara
Family Medicine, United States
Hospital, jacksonville, Florida

Mansour V. Shirbacheh
Surgery, assau County Medical Center, East
Meadow, ew York

e

Christopher D. Sprowl
Family Practice, St. joseph Hospital, Denver,
Colorado

Irwin C. Steinberg
Obstetrics/Gynecology, Winthrop Universi ty
Hospital, Mineola, New York

Paul D. Seeman
Family Practice, United States avy aval Hospital,
jacksonville, Florida

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•

Maria New, M.D~ thanks her patients as
she delivers 1993 D. WHarrington Lecture

common symptom of the disorder) aggravated by stress.
In her study of this disorder, ew
identified its "nonclassical" form- a late
onset hyperplasia in which the patient
acquires the symptoms of the disease after
HLA-TYPING LED TO DISCOVERY OF NONCLASSICAL
birth, rather than in utero. ew became
FORM OF CONGENITAL ADRENAL HYPERPLASIA
aware of this form using HLA-typing to
identify carriers in a specific family. Up to
this point in herresearch, HLA-typing had
en owned pediatric endocrinologist and then a male until adulthood, when the
predicted every outcome in her patients.
Maria I. ew, M.D., delivered the victim fell in love with and tried to marry
"It was all fine until we hit this family, "
1993 D. W. Harrington Lecture, a maid. "The maid was dismayed and ran
where ew noted that the deficiency wasn't
away," when the unfortunate patient pro"Congenital Adrenal Hyperplasia:
being passed on the way it was predicted
From the Laboratory to the Bed- duced a birth certificate that was for a baby
to .
girl rather than a boy. Although it was
'
~ side," recounting her research on
"We were very disappointed in the
believed "he died of a broken heart," in
the nonclassical form of the disorder.
nonconcordance of the HLA prediction."
Alexander Brownie, Ph.D., UB profes- fact, she said, he died of salt-wasting (a
ew discovered one particular family
sor and research professor in pathology,
member - a male with a mild deficiency
introduced ew, chair of pediatrics at
on one of the sixth chromosome pair and
Cornell Medical College. A friend of ew's
a major deficiency on the other. She defor over 20 years, Brownie described her
scribed the man's son "like no patient I
dedication to the field of pediatric endohave ever seen," noting that the son should
crinology, recounting how she always
have had the deficiency at birth but in fact
wanted to have a positive impact on childid not, nor did his sister who had the
dren suffering from endocrine disorders.
same HLA gene type.
ew thanked many for their help in her
Symptoms of the nonclassical form inresearch , but she made a special point to
clude
infertility and rapid growth. One of
100
thank her patients, "some of whom I have
the most common symptoms is frontal
followed from the time they were born
hair loss. Treatment can help eliminate
until they were parents."
many of these symptoms.
Pediatrician-in-chief and director of
Statistics show that the severe classical
the pediatric metabolism clinic at The
disorder occurs in one in 14 ,554live births,
ew York Hospital, ew has concenalthough there are some geographic variatrated her studies on the 21-hydroxylase
tions; Alaska's Yupik Eskimos show the
deficiency, which along with the 11-hyhighest frequency of the classical form.
droxylase defect, is one of the most comew described how she "never exmon forms. The deficiency causes an inpected what I got" when she tested the
creased secretion from the adrenal gland
genetic axiom that mild disorders occur
of cortisol precursors and androgens, remore frequent than severe ones. She said
sulting in masculinization of the female
she expected the frequency of the mild
external genitalia during intrauterine life.
deficiency of congenital adrenal
First described in 1854, the disorder
hyperplasia to be somewhere around one
can lead to female infants being sexually
in 13,000 live births, and was shocked
misassigned at birth, as well as precocious
when she realized it was much higher. A
sexual maturation in boys. New told the
11
test on Eastern Europeanjewsshowed the
story of that case, in which an Italian
frequency to be one in 27 and a test on
patient- raised as a female until age four,
Hispanics in New York showed a fre-

~I

Overall, the frequency

average of congenital

adrenal hyperplasia is

one in

who shows

symptoms, while one in

seven is a carrier, making

it the most common

autosomal recessive

defect. New called for

universal testing, but

lamented the fact that

only

states have

mandated it thus Jar.

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�quency of one in 40. Overall the frequency
average of congenital adrenal hyperplasia
is one in 100 who shows symptoms, while
one in seven is a carrier, making it "the
most common autosomal recessive defect. " ew called for universal testing, but
lamented the fact that only 11 states have
mandated it thus far.
Treatment begins in the womb as fetal
cells are Hl.A-typed. "When you get a
diagnosis by amniocentesis, it's already
too late," ew said. Dexamethasone is
used to treat the fetus at risk even before
the gender has been determined. If it is
later found the fetus is a male, treatment is
ended; females are treated until term. ew
said treatment can lead to recovered fertility and the lessening of other symptoms
"without causing complications.
"It's still a very experimental procedure," explained ew, "but I am very
respectful of human life."
The author of more than 400 research
papers on abnormalities of the adrenal
gland, New is immediate past presidentof
the Endocrine Society. In 1988, she received the society's Robert H. Williams
Distinguished leadership Award in Endocrinology. She has received the New
YorkAcademyofMedicineMedalofAward
and the Due Case award from the Office of
the Governor of ew York. She was elected
a fellow of the American Academy of Arts
and Sciences in 1991.
The Harrington lecture is sponsored by
the School of Medicine and Biomedical
Sciences. As Harrington visiting professor, ew spent two days meeting with
faculty and medical students in hospital
grand rounds, at clinics and in informal
discussion groups.
The D. W. Harrington lecture Fund
was established in 1886 by Devillo White
Harrington, M.D. , an 1861 graduate of the
UB medical school and a professor of
genito-urinary and venereal diseases from
1886 to 1905.
+

r'

Maria New, M.D.

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OLLIO

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~
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The aim of both initiatives is to provide
cooperative patient care networks for diverse specialty services to residents of the
West Side close to their homes as well as to
develop cost-effective access to University-affiliated tertiary care services to medically underserved communities.
Prenatal services will be provided at the
Buffalo Columbus' Family Care Center by
clinical faculty of the department of gynecology and obstetrics. Women receiving
prenatal care at the Buffalo Columbus
facility will be referred primarily to CHOB
for deliveries, as well as for any specialized
pregnancy-related care.
Additionally, women seen for gynecological services at the Family Care Center
will be referred to either Children's or Erie
County Medical Center.
The agreement was
forged
through the
joint efforts
of john P.

BlFFALO COL.lMIUS
HOSPITAL

UB-Columbus agreement provides cooperative
patient-care services for West Side residents.

UB-Columbus Hospital linkage to
provide prenatal care services
new agreement to enhance access to
women's health and AIDS services
to residents of Buffalo's West Side
community has been inked between
the School of Medicine and Biomedical Sciences, The Children's
Hospital of Buffalo, Erie County Medical
Center and the Buffalo Columbus Hospital.
The agreement, which establishes a
primary-tertiary care network to provide
comprehensive women's services, includes
provisions for delivering early prenatal
care to an area with some of New York
State's highest infant mortality rates. The
agreement also provides for the training of
local medical and nursing staff by specialists ofECMCS AIDS program to administer routine primary medical and specialized ambulatory care to AIDS and HIVpositive patients.

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president
for clinical affairs and
dean of the medical school,
and the hospitals. At a
press conference and luncheon announcing its es-

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UB oiTers GRATEFUL MED through
National Library of Medicine grant
B's Health Sciences Library has been
awarded a 15-month outreach contract to promote library services to
75,000 health care professionals
throughout Western and Central
ew York.
The library will do this through its
Western New York Outreach Program,
which began in August1992 and will run
through this October, funded by a
$159,699 ational Library of Medicine
(NLM) contract awarded through the ew
York Academy of Medicine. The program will introduce its audience to
GRATEFUL MED, a software package that offers desktop access to biomedical information and will link unaffiliated health professionals to

library services.
Cynthia Bertuca, head of information
dissemination services for the Health Sciences Library, said the program currently
targets more than 10,000 pharmacists and
dentists in a 25-county area. The counties
involved are the eight counties ofWestern
ew York, plus Steuben, Livingston, Mon-

GRATEFUL MED reaches out.

5

tablishment, Naughton was lauded by Columbus Hospital board members for his
community service and efforts on behalf
+
of Buffalo's West Side.

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�. .. . . . .. ... ..... .... . .. .... . . . .... . .... ... ...... .... ......... . . ..... . ... . ..... ... . . . . .. ....

••• ••~
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roe, Ontario, Wayne, Cayuga, Yates, Seneca, Schuyler, Chemung, Tompkins,
+
Cortland and Tioga.

New plan turns private practices
into formal classrooms in WNY

the memory of the associate professor of
medicine at New York University School
of Medicine who served as a member of
MF's board from 195 2 until his death in
1979.
+

The Graef Memorial Scholarship was
established by the ational Medical Fellowships (NMF) board of directors and
endowed through a gift from the Irving
Graef Medical Fund. The award honors

our doctors' offices, an inner-city
health clinic and an HMO in Western ew York are becoming the
nation's first private medical practices to function as formal training
sites for medical students and resident physicians studying to become primary care physicians.
The program is called the Community
Action Practice (CAP) project, a cooperativeventure of the Graduate Medical Dental Education Consortium ofBuffalo. CAP
is part of a $5 million primary care initiative unveiled by the Consortium last fall ,
designed to increase the number of resident physicians training in primary care
from 35 to 50 percent by 1994. The new
program will allow aspiring doctors to
study primary care medicine where it is
practiced- in doctors' private offices and
walk-in clinics rather than in hospitals,
the traditional training ground for all fields
of medicine.
Computer software and hardware will
also be provided on-site as part of the new
program.
+

UB medical student wins Irving
Graef Memorial National Medical
Fellowships scholar award
ndrea Williams, a University at Buffalo medical student, has been chosen as the 1992-93 Irving Graef
Memorial Scholar. As the Graef
Scholar, Williams will receive
$2,000 during her senior year.

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Andrea Williams

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�. . . . .

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••••••••••••••••• ••••••••••

. . . . .... . . . . . . . . . . . . . . . ..

. . .

UB'sOffice of Graduate Medical
Education is key to excellence in
Consortium residency training
oseanne Berger, M.D., UB's new
associate dean for graduate medical
education has her capable hands
full. Her office - the Office of
Graduate Medical Education and
House Staff Affairs - is charged
with overseeing not only the education of
over 700 resident physicians, but the many
functions associated with coordinating
their education through the school's
Graduate Medical Dental Education Consortium of Buffalo (GMDECB).
Founded 10 years ago in an effort to
respond to new guidelines issued by the
Liaison Committee on Graduate Medical
Education, the GMDECB consists of the
School of Dental Medicine, the School of
Medicine and Biomedical Sciences and its
nine affiliated teaching hospitals, all residency training program directors and one
resident from each program.
Before her office was established last
October, Berger says "graduate medical
education was spread among the hospitals, with some residents sent to multiple
hospitals without any coordination between them. One resident may have gotten a salary from one hospital and rotated
to three hospitals and his or her colleague
might have received a different salary from
another hospital and essentially do the
same thing. And benefits were a problem,
too."
In addition, Berger adds, the accrediting body for graduate medical education
"required an institution of record to hold
responsible for ensuring the quality of the
programs. In Buffalo, we had eight hospitals - and who was responsible for the
quality?
"That function is now focused out of
this office."

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Roseanne Berger, M.D.
The office also serves as a clearinghouse for Consortium residency program
directors to learn about accreditation information and other issues affectinggraduate medical education. "For example,"
Berger explains, "the impact health care
reform being anticipated from Washington will have on graduate medical education- that type of effort comes out of this
office."
Issues common to all residency programs are coordinated through the medical school's graduate medical education
department. "Because there are multiple
residency programs, there are certain issues common to all programs that are
managed more efficiently if coordinated
through one office," Berger says, and cites
the Consortium's one-week residency program orientation as an example.
'The residents learn about communication skills, teaching skills, issues in
medicine such as advanced directives,
documentation, medical records, and also
receive training in life support and advanced life support- all issues common

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....................................

to all programs and important for the new
house staff to know. "
As the medical school's chief liaison to
the Consortium, Berger's office is poised
to take an even broader role, given the
current climate of health care reform that
is likely to touch not only practicing physicians, but both graduate and undergraduate medical education as well.
That climate, Berger notes, will probably result in striking changes in the way
physicians- particularly resident physicians- are trained in this country.
And UB and its Consortium- having
committed to achieving 50 percent of its
residency positions in primary care "are on the forefront of change because we
are a Consortium and in the future graduate medical education will look toward
developing more. We are the oldest and
we are looked at as a model for the nation,
having worked collaboratively with the
hospitals. "
The 50 percent primary care residency
goal is only one objective of a three-year
ew York State Department of Health
demonstration project Berger's office also
has responsibility for. That demonstration project is aimed at easing the nation's
current and projected shortage of primary
care physicians.
"We've made a commitment to make
changes in graduate medical education in
exchange for more favorable reimbursement rates. This is a key reason why this
office was established," Berger said.
"We have to demonstrate we're making the changes we've committed to making. And these are exactly the kind of
changes the government and health care
planners feel need to be made in this
country in terms of health care delivery
and medical education.
"We have a leg up on things because
we've already committed to making these
kinds of changes."
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II
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Listing of Consortium residency programs demonstrates
expanded specialty scope as well as focus on primary care
he Graduate Medical Dental Education Consortium of
Buffalo is responsible for the education of over 700
resident physicians. Following is a listing of the programs
the Consortium runs, including the affiliated hospitals,
program directors and number of positions in each
program.
ALLERGY AND IMMUNOLOGY

Hospitals
Buffalo General Hospital
The Children's Hospital of Buffalo
Erie County Medical Center
Program Director
Dr. Mark Ballow
umber of Positions - 4
ANESTHESIOLOGY

Hospitals
Buffalo General Hospital
The Children's Hospital of Buffalo
Erie County Medical Center
Millard Fillmore Hospitals
Roswell Park Cancer Institute
VA Medical Center
Program Director
Dr. Richard Ament
Number of Positions - 52

VA Medical Center
Program Director
Dr. Clara Bloomfield

E DOCRINOLOGY AND
METABOLISM
Hospital
Erie County Medical Center
Program Director
Dr. Stephen Spaulding

EPHROLOGY
Hospital
Erie County Medical Center
Program Director
Dr. Rocco Venuto

GASTROENTEROLOGY
Hospital
Erie County Medical Center
Program Director
Dr. Milton M. Weiser

INTERNAL MEDICINE PROGRAM A

Hospitals
Buffalo General Hospital
The Children's Hospital of Buffalo
Erie County Medical Center
VA Medical Center
Program Director
Dr. Robert Scheig
Number of Positions- 156
(iJicludi,gfellowships )
Programs
CARDIOVASCUlAR
DISEASE
Hospital
Erie County Medical Center
Program Director
Dr. Avery K. Ellis

PULMONARY DISEASES
Hospital
Erie County Medical Center
Program Director
Dr. Alan R. Saltzman

HEMATOLOGY-MEDICI E
Hospital
Erie County Medical Center
Program Director
Dr. Gerald Logue

RHEUMATOLOGY
Hospital
Erie County Medical Center
Program Director
Dr. Floyd A. Green

INFECTIOUS DISEASES
Hospital
Erie County Medical Center
Program Director
Dr. Timothy Murphy

INTERNAL MEDICINEPROGRAM B

MEDICAL ONCOLOGY
Hospitals
Buffalo General Hospital
Roswell Park Cancer Institute

Hospital
Millard Fillmore Hospitals
Program Director
Dr. joseph lzzo
umber of Positions- 3 7

DERMATOLOGY

Hospitals
Buffalo General Hospital
The Children's Hospi tal of Buffalo
Erie County Medical Center
Roswell Park Cancer Institute
VA Medical Center
Program Director
Dr. Stephanie Pincus
umber of Positions- 10
FAMILY PRACTICE

Hospitals
Buffalo General Hospital
Cuba Memorial Hospital
Erie County Medical Center
Millard Fillmore Hospitals
Olean General Hospital
Program Director
Dr. Daniel Morelli
umber of Positions - 52

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VA Medical Center
Program Director
Dr. George Simpson
Number of Positions -

PSYCHIATRY

Hospitals
Buffalo General Hospital
The Children's Hospital of Buffalo
Ene County Medical Center
VA Medical Center
Program Director
Dr. Seung-Kyoon Park
Number of Positions - 26

12

PATHOLOGYANATOMICAL CLINICAL

Hospitals
Buffalo General Hospital
Erie County Medical Center
Roswell Park Cancer lnslllute
VA Medical Center
Program Director
Dr. Reid Heffner
umber of Positions - 19

CHILD PSYCHIATRY

PEDIATRICS

NEUROLOGICAL SURGERY

Hospitals
Buffalo General Hospital
The Children's Hospital of Buffalo
Erie County Medical Center
Program Director
Dr. L. Nick Hopkm
Number of Positions - 7
NEUROLOGY

Hospitals
The Children's Hospnal of Buffalo
Buffalo General Hospnal
Erie County Medical Center
Millard Fillmore Hospnals
VA Medical Center
Program Director
Dr. Michael Cohen
Number of Positions- 16
CHILD NEUROLOGY

Hospitals
The Children's Ho pnal of Buffalo
Erie County Medical Center
VA Medical Center
Program Director
Dr. Michael Cohen
NUCLEAR MEDICINE

Hospitals
Buffalo General Hospnal
Mercy Hospital
Roswell Park Cancer lnslllute
VA Medical Center
Program Director
Dr. joseph Prez10
umber of Positions - 6

Program Director
Dr. Myroslaw Hreshchyshyn
umber of Positions - 40
OPHTHALMOLOGY

Hospitals
Buffalo General Hospital
The Children's Hospital of Buffalo
Ene County Medical Center
VA Medical Center
Program Director
Dr. William Coles
umber of Positions - 12
ORTHOPAEDIC SURGERY

Hospitals
Buffalo General Hospital
The Children's Hospital of Buffalo
Ene County Medical Center
Mercy Hospital
VA Medical Center
Program Director
Dr. Lawrence Bone
umber of Positions - 16
Programs
HA D SURGERY
Hospitals
Millard Fillmore Hospitals
Erie County Medical Center
Program Director
Dr. Clayton Peimer
umber of Po it ions 3
PEDIATRIC ORTHOPAEDICS
Hospital
The Children's Hospital of Buffalo
Program Director
Dr. Robert Gillespie
umber of Positions- 1

GYNECOLOGY AND
OBSTETRICS

Hospitals
Buffalo General Hospnal
The Children's Hospnal of Buffalo
Erie County Medical Center
Millard Fillmore Hospitals
Roswell Park Cancer Institute

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Hospitals
The Children's Hospital of Buffalo
Ene County Medical Center
SISters of Charity Hospital

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Hospitals
The Children's Hospital of Buffalo
Erie County Medical Center
Mercy Hospital
Roswell Park Cancer lnslllute
Program Director
Dr. Gerald Daigler
Number of Positions - 71
(includi ngfellowships)
Programs
EO ATAUPERJ ATAL
MEDICI E
Hospital
The Children's Hospital ofBuffalo
Program Director
Dr. Frederick Morin
PEDIATRIC EPHROLOGY
Hospital
The Children's Hospital ofBuffalo
Program Director
Dr. Leonard Feld
PEDIATRIC HEMATOLOGYONCOLOGY
Hospitals
The Children's Hospital ofBuffalo
Roswell Park Cancer Institute
Program Director
Dr. Martin Brecher
PEDIATRIC ENDOCRINOLOGY
Hospital
The Children's Hospital ofBuffalo
Program Director
Dr. Margaret MacGillivray
PHYSICAL MEDICINE AND
REHABILITATION

Hospitals
Buffalo General Hospital
The Children's Hospital of Buffalo
Ene County Medical Center
Mercy Hospital
Sisters of Charity Hospital
VA Medical Center
Program Director
Dr. Kyu Ha Lee
Number of Positions - 13

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Hospitals
The Children's Hospital of Buffalo
Western New York Children's
Psychiatric Center
Program Director
Dr. David Kaye
umber of Positions - 6
RADIOLOGY

Hospitals
Buffalo General Hospital
The Children's Hospital of Buffalo
Erie County Medical Center
Millard Fillmore Hospitals
VA Medical Center
Program Director
Dr. Angelo De!Balso
umber of Positions- 18
Programs
PEDIATRIC RADIOLOGY
Hospital
The Children's Hospital of
Buffalo
Program Director
Dr. jerald Kuhn
SOCIAL AND PREVENTIVE
MEDICINE

Hospitals
Buffalo General Hospital
Program Director
Dr. Michael oe
Number of Positions - 7
SURGERY

Hospitals
Buffalo General Hospital
Erie County Medical Center
Millard Fillmore Hospitals
VA Medical Center
Program Director
Dr. Eddie Hoover
Number of Positions - 72
Programs
COLO AND RECTAL
SURGERY
Hospital
Buffalo General Hospital
Program Director
Dr. Bertram Portin
umber of Positions - 1
PEDIATRIC SURGERY
Hospital
The Children's Hospital of
Buffalo

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Program Director
Dr. james Allen
Number of Positions - 2

Erie Count)' Medical Center
VA Medical Center
Program Director
Dr. joseph Margarone
Number of Positions - 8

VASCUlAR SURGERY
Hospitals
Buffalo General Hospital
Millard Fillmore Hospitals
VA Medical Center
Number of Positions - 2

PEDODO TICS
Hospital
The Children's Hospital of
Buffalo
Program Director
Dr. joseph Bernat
umber of Positions- 4

THORACIC SURGERY

Hospitals
Buffalo General Hospital
The Children's Hospital of Buffalo
Millard Fillmore Hospitals
Roswell Park Cancer Institute
VA Medical Center
Program Director
Dr. Eddie Hoover
umber of Positions - 4
UROLOGY

Hospitals
Buffalo General Hospital
The Children's Hospital of Buffalo
Millard Fillmore Hospitals
Roswell Park Cancer Institute
VA Medical Center
Program Director
Dr. Gerald Sufrin
umber of Positions - 9

AFFILIATED PROGRAMS

MERCY HOSPITAL
Program
Internal Medicine
Program Director
Dr. Thomas Raab
umber of Positions -

23
NIAGARA FALLS MEMORIAL
HOSPITAL
Program
Family Practice
Program Director
Dr. M. Oyster
umber of Positions - 12

Program
Gynecology and Obstetrics
Program Director
Dr. Michael Ray
umber of Positions- 8

SISTERS OF CHARITY HOSPITAL
Program
Internal Medicine
Program Director
Dr. elson Torre
Number of Positions- 20

DENTAL PROGRAMS

GENERALPRACTICE DE TISTRY
Hospital
Buffalo General Hospital
Program Director
Dr. Alan Drinnan
umber of Positions - 6
GENERALPRACTICE DE TISTRY
Hospital
Erie County Medical Center
Program Director
Dr. Stuart Fischman
umber of Positions - 6
GENERALPRACTICEDE TISTRY
Hospital
VA Medical Center
Program Director
Dr. Gene lnneo
Number of Positions- 5
GE ERALPRACTICEDENTISTRY
Hospital
Millard Fillmore Hospital
Program Director
Dr. Sanford usbaum
umber of Positions - 3
ORAL AND MAXILLOFACIAL
SURGERY
Hospitals
Buffalo General Hospital

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I

�"The Name of the Game" in health care
reform today is reasonable change
JAMES TODD , M .D. , GIVES STOCKTON KIMBALL LECTURE

s he spoke in sports analogies and
anecdotes,] ames Todd, M.D.'s message was clear: any change in the
American health care system will
have to be "slow and reasonable. "
Executive vice president of the
American Medical Association, Todd delivered the Stockton Kimball Memorial
Lecture- "The arne of the Game" - at
this year's Spring Clinical Day, held May 1.
Margaret Paroski, M.D. , '80, assistant
professor of neurology and Spring Clinical Day chairperson, introduced Todd to
an audience of about 300. "If you read
Time or Newsweek , I don't need to introduce you to Dr. Todd, because every time
you hear anything about Hillary Clinton
dealing with theAMA,you'llsee Dr. Todd's
name."
Todd explained how he sees health
care as a game, with "rules, regulations,
goals, winners and losers. Meanwhile, we
and our patients are out on the playing
court, fighting our way to a goal that
sometimes seems only we continue to see.
But unlike any other endeavor, there are
also some rules, in this case called antitrust, that prevent doctors from working
out their own team game plan. "
Todd called UB "a grand example of
how you can coordinate the education of
students, the needs of the community and
become a very cooperative activity to teach
and advance the art and science of medicine."
He lauded Stockton Kimball by saying,
"Dr. Kimball was noted for many different
achievements: for his knowledge of tropical disease, for his dedication to improving the physical facilities of your campus,
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nity of ew York State.
"His involvement, his brand of humanitarianism, his
genuine caring, personify the characteristics, the kind of personal concern which
draws us all when we think about going to
medical school."
Todd said he saw a connection between Kimball's work and the theme of
this year's Spring Clinical Day lecture,
noting that in 1950 Kimball chaired a
special AMA committee to study medical
training in times of war and crisis called
the joint Committee on Medical Educa-

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tion at the Time of National Emergency.
"How appropriate that is. And how
very germane that is to my being with you
this afternoon. Because if there was ever a
time of national emergency in health care,
we're facing it today. "
The crisis is so compelling, Todd said,
that "Mrs. Clinton has assembled a committee of 500 to find a solution. I'm not
telling you it's a professional emergency
-although it is that- nor is it a patient
emergency- but it is that, too. The state
of health care in this country is a national
emergency-one that touches every single
citizen of the United States," Todd said.
"It touches the 87 percent for whom
the current system has essentially been
working pretty well. And it especially
touches the 3 7 million people who are
denied access to the system because of
insurance regulations, loss of jobs or a
dozen other quirks and loopholes.
"These have rendered the
basics of health care out of
reach for too many for too
long. And it is not a secret to
anyone anymore that the
present system is unsustainable.
" either patients nor doctors can stand too much more
of our present system. "
Todd explained how he
thought that the "future in the
medical sciences will be limited only by our imaginations.
Indeed, if the Clinton administration does the job that all of
America hopes they'll do, I
think we will have a lot to look
forward to as far as returning
to the goals that motivated us
as physicians. "
Todd warned of the dangers of mixing politics and
medicine. "If Clinton and
Clinton get stuck in the thicket

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�of political and practical miscalculations,
we will all suffer-especially our patients.
"The stakes are even higher than our
own professional standing. And the name
of the game I am talking about is patient
care. Rules are being written even as we
speak," Todd said.
"Well, I'm no slam-dunker myself, but
I do know this: there's not a coach in the
world who doesn't try to improve on player
performance."
Todd noted that various strategies for
rescuing the American health care system
have already been proposed, adding that
the AMA was one of the first organizations
to put forth a plan.
"We put a plan on the table known as
Health Access America. It is the American
way to reform the health care system. It
seeks to bring to patients an essential set of
benefits, universal access, cost containment, equity - while at the same time
working to bring doctors relief from regulations."
Todd believes the key to reforming the
health care system is "not just change, but
reasonable change.
"Responsible change is the winning
strategy. Today, patients are sent into a
system so wrapped up in red tape they can
hardly maneuver. Doctors half the time
are playing with one hand tied behind our
backs. We are coming under scrutiny that
seeks to punish and not to educate, sending us racing full-tilt into the shelter of
defensive medicine, so we don't get sued
or worse," Todd said.
''I'm sure all of you would welcome a
world in which you could follow your best
clinical judgment and return the profession to the ability to discipline itself."
But change will not occur, Todd said,
unless "we show restraint in our behavior
in what's going on around us. We have to
focus on responsibility to our nation. We
cannot afford to think of medicine as a
spectator sport. We have to have active
participation."
+
BY
B

u

CARRIE

a

Calls for membership in the James Platt White Society went out from medical ~chool ~lumni during a
special membership drive held last April. From left are: Albert G. Rowe, M.D., 61; R1chard R.
Romanowski, M.D., '58; Michael A. Sansone, M.D., '85; Angelo M. DeiBalso, M.D., '78; Lawr~nce E.
Mervine, assistant dean and senior development officer with the University at Buffalo Foundation;
Arthur W. Mruczek, Sr., M.D., '73, and Elizabeth P. Olmsted, M.D., '39.

Frawley '44 receives prestigious
Alfred Stengel Memorial award
homas F. Frawley, M.D., '44, has
been awarded the 1993 Alfred
Stengel Memorial Award. The
American College of Physicians
award, established in 1947, is given
to a Master of the College who has
exhibited "unusual loyalty and exceptional
contributions to the aims and purposes of
the College as well as outstanding influence in maintaining and advancing the
best standards of medical education, medical practice and clinical research."
Frawley, the 1989 recipient of UB's
Distinguished Medical Alumnus Award,
is a professor emeritus and chairman of
the Department of Graduate Medical Education of St.john's Mercy Medical Center,
St. Louis, Missouri.

A governor of the
American
College of
Physicians,
he served as
that group's
president
from 1981
to 1982.
Frawley ,
who has
been active
on research
and evaluation committees of the ationallnstitutes ofHealth,
the ational Academy of Sciences and the
American Medical Association, received
his award in March at the American College of Physicians' Convocation held in
+
Washington, D.C.

LIBERANTE

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�hkhert

Kenneth Eckhert M.D~ Sr~ lauded
by Niagara Lutheran Home
he iagara Lutheran Home Foundation presented Dr. Kenneth
Eckert, M.D., '35, with its 1993
Humanitarian Award at a special
dinner in his honor last April.
Eckhert, a lifelong Buffalo resident, played a key role in the establishment of the Health Service Agency- the
first of its kind in Buffalo and the first to
receive federal funding. Eckhen served as
president of that agency, which was a
forerunner of today's Health Systems
Agency.
Eckhert and his long-time friend, the
Reverend Dr. Ralph Loew, were instrumental in the establishment of Trinity
Tower, a senior citizen residence developed in conjunction with Holy Trinity
Lutheran Church.
Eckhert is a member of the board of
trustees of the Niagara Lutheran Home
Foundation and currently serves on a
number of boards and medically related
associations. He served as chiefof surgery,
chief of staff and president of the executive committee of the fomer Deaconess
Hospital.
+

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American Academy of Family
Physicians honors UB physician

Harrts Directory begins survey of
UB medical school alumni

arlos Roberto jaen, M.D., '89, UB
assistant professor of family medicine, was one of eight physicians
honored recently by the American
Academy of Family Physicians for
their contributions to medicine and
public health.
Jaen received the Academy's McNeil
Clinical Research Award for his work,
"Symptoms Associated with Middle Ear
Effusion in Children: A Basis for Quantifying Clinical]udgment."
jaen came to the University at Buffalo
in October 1992
after completing a
fellowship and
residency in family practice at University Hospitals
of Cleveland, affiliated with Case
Western Reserve
University. He
holds a doctorate
in epidemiology
and a medical degree from the UB
School of Medicineand Biomedical Sciences. He
completed his undergraduate and
master's degree
work at iagara
University.
jaen's research
on tobacco dependence and
bladder
and
colorectal cancer
has been published in various
scientific journals.
+ Carlos Roberto Jaen, M.D.

s preparation for publishing an extensive medical school alumni directory, the Harris Company will begin
sending questionnaires to all alumni
with current addresses.
Please be sure to complete and
return your directory questionnaire as
soon as possible to help make the School
of Medicine and Biomedical Sciences' new
directory as complete as possible.
Alumni who fail to return their questionnaires may be inadvertently omitted
from the directory.
+

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�A

Spoonful

of

Humor

©

Stu

Silverstein,

M.D.

Health Care Reform It's No Joke • • •
Stu Sil\'erswn, M.D., prrs1drnl of Slandup Med1c1ne

Unless You Make It One

Srm1nars of San Franmco, Califorma, lee lures nal!onw1de
on humor in medicine

In the previous issue of Buffalo Physician we talked about the technique of
revamping old jokes with medical
themes for appropriate use when
addressing medical audiences.
Here are a few jokes and
anecdotes about an issue that
seems to be appearing everywhere- in the news, on these pages, in our nation~ capital, and
maybe even in our practices-the managed care movement in health
care reform.
• Recently, I was sitting in the doctors'
lounge, reading the AMA ews and Buffalo Physician. I spotted a friend reading a
government report on health care reform.
I asked him why he was wasting his time
reading that crap. He looked at the AMA
News I was reading and said, "What are
you reading about in there? How medicine is changing for the worse- managed
care is placing unrealistic restrictions on
us, our incomes will be going down, we won't
be able to practice the way we used to.
"You read that and get all depressed. I
read this and find out we're all millionaires, play golf on Wednesdays and will
continue to get rich despite health care
reform."
• I'm not sure ifl feel so good about two
lawyers revamping the health care system in this country. Do you get the
feeling that after four years in office
we're going to get a bill for 35,000 hours
for Hillary's services?

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''Asking the
government for
advice on how to
run health care is
like asking Sylvester
Stallone for acting
lessons.''

• Asking the governmentforadviceonhow
to run health care is like
asking Sylvester Stallone
for acting lessons.
• Hillary Clinton reminds me
of someone who takes your watch
off to tell you what time it is.
• I told my son that I wanted him to be
a partner in my practice, but it seems the
government will beat him to it.
• When I played hockey in high school,
I spent most of the time sitting on the
bench. In the last game of the season, we
were down by one goal with one minute to
go and no time outs left. The coach called
my name to send me in. I turned around to
get my instructions and he said, "We're
out of time outs and can't stop the clock.
Go in there and get hurt. "
As a doctor facing health care reform, I
feel as if I'm reliving that experience. +

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�• . ........... ... ... ..... . .................... ... ..

. . .. . .. . ......... . ......... . .........

medical practice, and clinical re-

governor to the American College

search ." Frawley served as presi-

of Surgeons for North Carolina.

dent of the College from 1981to
EUGENE A . PAUL '77 , writes,

1982.

"My time is divided between a

1

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full-time position as chief of the

5

medical clinic at Harlem Hospital

ROBERTA GILBERT '62 , in-

and a private general internal

forms us that the first printing of

medicine practice in Jamaica, ew

her new book, Extraordinary Re-

York. "

lationships: A ew Way of Thinking About Human Interaction, sold
out; the publisher is already be-

ORESETES G . ROSABAL '77 ,
Southern Medical Association's

ginning the second printing.

Bernard S. Stell

1

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State Councilor for Florida, reScientific Assembly of the Asso-

laboratory dire ctor at Coastal

0

5

BERNARD 5 . STELL '36, of

cently attended the 86th Annual

Mi(hael Rowland

CALVIN MARANTZ '65 , is now

ROBERT B . KROOPNICK '72 ,

Communities Hospital in Santa
Ana, California.

Sun City, Arizona, has received

was elected to fellowship in the

Rosabal, a specialist in orthopaedic

American College of Physicians.

and traumatic surgery, is in private practice in Hialeah, Florida.

the Diamond Star Award in the

DONALD J . WALDOWSKI '65 ,

Kroopnick is board certified in

Stereo Division of The Photo-

has a solo private pediatric prac-

internal medicine with additional

graphic Society of America.

tice at850 West High Street, Lima,

qualifications in geriatric medi-

Ohio.

cine.

pediatrics in Troy, ew York. "

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THOMAS F . FRAWLEY '44 ,

DOUGLAS H . MOFFAT '79 ,
recently assumed the position of
chief of medicine at Buffalo Psy-

WALTER Z. SCHWEBEL '83 ,
writes, "I am still in the practice of

ciation held in San Antonio, Texas.

ANTHONY B . SERFUSTINI '66 ,

RETA D. FLOYD'73,announces

chiatric Center.

is chairman of the department of

the opening of a new office at 924

orthopaedic surgery at the Uni-

Buena Vista, Suite 204, Duarte,

versity Medical Center in Las Ve-

California 91010. Outside of work,

EDWARD ROCKWOOD '80 ,

gas, evada.

Floyd is active in her church where

practices ophthalmology at Cleve-

she is a Sunday school teacher.

land Clinic Foundation. He and

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chairman of graduate medical

JOHN E . SPOOR '66 , writes, "I

She also is active in the Pasadena!

education at St. John's Mercy

his wife Joan (former Millard

have been named the editor of the

Altadena chapter of Links -

Medical Center and emeritus pro-

Fillmore Medical Education sec-

Section on Rural Emergency Medi-

women's civic organization. Floyd

fessor of medicine at St. Louis

cine Newsletter- ACEP."

lives in Altadena with her hus-

University School of Medicine,
was the 1993 recipient of the Alfred
Stengel Memorial Award presented by the American College of
Physicians. The award is given
periodically to a Master of the
College who has exhibited "unusual loyalty and exceptional con-

a

DANIEL P . SCHAEFER '81 , a

band and two children.

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retary) have three daughters.

UB clinical assistant professor,

5

ELLIOTT SCHULMAN '74, has

RONALD H . BLUM '70 , has
been appointed deputy director
of the Kaplan Comprehensive
Cancer Center at New York University Medical Center.

been elected a fellow of the Ameri-

attended the American Society of
Ophthalmic and Plastic Recon-

can College of Physicians. In ad-

structive Surgery meeting in Dal-

dition to lecturing extensively on

las, Texas. A member of the Edu-

headaches, he is co-director of the

cation Committee, he assisted in

Comprehensive Headache Cen-

giving written and oral examina-

tributions to the aims and pur-

BRUCE M . PRENNER '70 , was

ter at the Germantown Hospital

tions to the candidates for mem-

poses of the College as well as

in Philadelphia, Pennsylvania.

bership in the society.

outstanding influences in main-

invited to present clinical research
on asthma before the European

taining and advancing the best
standards of medical education,

Respiratory Society in Vienna ,
Austria, in August.

MICHAEL ROWLAND '75 , of
Pinehurst,

orth Carolina, was

elected to a three-year term as

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II
•

DEIRDRE GREENE '86 ,

Elliott Schulman

writes,

JEFFREY WASSERMAN

'82 ,

writes, "Vickie and I now reside in

doing pediatrics. My husband,
Rob Dixon, and I now have two
kids - Patrick,3, andAurora, 16

Rochester, ew York, with our
two sons, Robb, age 6, and Steven,
age 4. After my residency in anes-

months."

thesiology, I spent one year as an

MICHAEL S .

academic anesthesiologist at the
University of Rochester's Strong

MILLER

'86 ,

writes, "I am an assistant profes-

Memorial Hospital. I am now in

sor of psychiatry and a full-time
faculty member of the University

private practice at Rochester General Hospital."

of Texas Health Science Center at
San Antonio. My wife, Pamela,

MARGARET

and I have two beautiful children

writes, "I completed my pediatric

-

Laura L. Post

Matthew, age 3, and Jeffrey,

D . JENKINS

a senior fellow in the Robert

TINA GARDNER '87 ,
ROSLYN
'86 ,

R.

ROMANOWSKI

sion of hematology/oncology and

Washington, will receive her MPH
in Epidemiology in June 1993.

Harvard Medical School instructor, received a five-year Clinical

SARAH MURRAY WHITE '85 ,

Investigator Development Award
(CIDA) totaling $385,000 from
the National Heart, Lung and

writes, "I have recently joined an
Washington, D.C., where I practice rehabilitation medicine and
perform electrodiagnosis. We are
at the Washington Hospital Center. My husband, Bill, son
Cameron, two and one-half years
old and I live in Annapolis, Maryland. I recently spoke with
Gretchen Pankow '87, who will
be doing an endocrine fellowship
at Massachusetts General (unless
she changes her mind)."
KARIN E . CHOYS '86 ,

writes,

''I'm a practicing pediatrician with
the Kaiser Permanente HMO in
the Hartford, Connecticut area. I
am also happily divorced and enjoying 'flying solo!"'

address is St. Regis Mohawk Tribe
Health Services, do Community
Building, Hogansburg, ew York.
LAURA L. POST '87 ,

SHAUGHNESSY '86 ,

writes, "I have moved back to
Boston with my partner, Rick, and
combine private practice, mental
health center work and a teaching
appointment at Harvard Medical
School and McLean Hospital."
RAY 800RADY '87,

has been

medical director of Operation
Concern, a lesbian/gay community mental health and services
agency in San Francisco. She is
active in research on lesbian mental health in addition to having a
prolific writing career in women's
music and culture. Post and her
partner, Judith Avery, R.N.C. ,
have two sons and one grandchild, Karen, who is 18 months

Blood Institute to investigate the
erythropoietin receptor - how
red blood cells are produced.
JAM E S

writes, "I

have moved to northern ew York
and am working for the Mohawks.
It's beautiful up here! " Her new

a staff physician in the divi-

Wood Johnson Clinical Scholars
Program at the University of

orthopaedic surgery group in

old.

currently

chief of the psychiatry clinic at
Massachusetts General Hospital,
completed four years in youth psychiatry and will finish a two-year

STEPH E N C . SORENSON '87 ,

informs us that he completed an
emergency medicine residency in
Louisville, Kentucky, and is pres-

fellowship in psychiatry in June.
He has accepted a two-year staff
position at Harvard. Boorady re-

ently in private practice. He marriedJudith Bellville on September
19, 1992, in Louisville.

cently attended an international

A . MOREY '88,

residency at Rainbow Babies and
Children's Hospital, Cleveland.
After a much-needed hiking trip
in New Zealand, I'm beginning a
fellowship in adolescent and
young adult medicine at the
Children's Hospital in Boston."
is
now director of clinical and regulatory organogenesis in CamM ICHAE L SABOLI NSK I '88 ,

bridge, Massachusetts.
PAUL SHIELDS '88,

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has a pri-

vate practice in internal medicine
in Naples, Florida. In October he
joined the aples Medical Center, specializing in internal medicine.
CHARLES S . P . J E N KI NS '89 ,

of Chapel Hill, North Carolina,
informs us, "Got married. Doing
well. Will be hearing the pitterpatteroflittle feet soon. Seeya'll."
KENN ETH P . SUN '89 ,

is cur-

rently an anesthesiology resident
at St. Luke's Roosevelt Hospital
Center, ew York.
TRAC I TROUP '89 ,

has joined

the department of family practice

convention in Paris.

e

'87 ,

"Still in Allentown, Pennsylvania,

age 17 months."
LAURACINNIE

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.. . . . . . ...................................................................................

I

at Group Health , Inc.'s St. Paul
Medical &amp;: Dental Center, in St.
Paul , Minnesota.

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ELI Z ABETH CONROY

5

'92 , and

her husband jeff, announce the
birth of their son, Dylan Reid, on
january 8, 1993. She is currently
in a dermatology residency at the
Cleveland Clinic Foundation .

OBITUARIES
RUTHERFORD
FORD

5 .

RUTHER ·

'41 , died in Dillon Beach,

California,

ovember 27, 1992,

after a long illness. Rutherford
was chief of staff and founder of
Marin General Hospital in 1955;
founder of Marin Organ Bank and
Marin County Heart Association.
He was the author of over 100
scientific and medical papers.
L L OYD

M.

LEHRER

'79 , died

February 22, 1993, due to the
effects of Behcet's Syndrome. In

Beginning with our Autumn 1993 issue, our readers will hove the opportunity to learn more about
products and services of interest to them. We ore happy to provide advertisers the opportunity to
shore their product information with our unique readership who number more than 10,000.
For additional information, please contact our Advertising Manager.

addition to his private practice in
Houston , he served as an assistant
clinical instructor of medicine at
Baylor College of Medicine , chair-

•

man of the department of medicine at Bellaire General Hospital
and chairman for public education for the American Cancer So-

University ot Buffalo Publications Deportment

ciety, where he was honored for
his work by the State of Texas. He

136 Crofts Hall

is survived by his wife, Susan, and
his sons, Benjamin and Michael ,

Buffalo, New York 14260

of whom he was so proud.

Phone: (716) 645-2626
FAX: (716) 645-2313

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��BUFFALO PHYSICIAN
STATE UNIVERSITY OF NEW YORK AT BUFFALO
3435 MAIN STREET
BUFFALO NEW YORK 14214

ADDRESS CORRECTION REQUESTED

Non-Profit Org .
U.S. Postage
PAID
Buffalo, NY
Permit No. 311

�</text>
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                <text> "He captured my heart in a way that patients aren't supposed to."</text>
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                <text> Graduate Education</text>
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                    <text>Biomedical Sciences, Autumn 1993

�BUFFALO PHYSICIAN

Volume 27, Number 4
ASSOCIATE VICE PRESIDENT
FOR UNIVERSITY
ADVANCEMENT

Dr Carole Smith Petro
DIRECTOR OF PUBLICATIONS

Timothy J Conroy
EDITOR

anette Tramont Kollig, R.N.
ART DIRECTOR

Alan J. Kegler
ASSOCIATE ART DIRECTOR

Scoll Fncker
PRODUCTION MANAGER

Ann Raszmann Brown
STATE UNIVERSITY OF NEW
YORK AT BUFFALO SCHOOL
OF MEDICINE AND
BIOMEDICAL SCIENCES

Dr John Naughton, Vice President for
Clinical Affairs, Dean
EDITORIAL BOARD

Dr John A. Richert, Chairman
Dr Martin Brecher
Dr. Harold Brody
Dr Richard L. Collins
Dr. AlanJ. Drinnan
Dr. Timothy Gabryel
Dr. James Kanski
Dr. Charles Massaro
Dr Charles Paganelli
Dr Robert E. Retsman
Dr Thomas Rosenthal
Dr Stephen Spauldmg
Dr Bradley T Truax

Dear Friends,

T

wo major milestones are reported in this issue of Buffalo Physician. The first relates
to the dedication of the Center for Positron Emission Tomography that occurred m
mid-May. That dedication served to culminate several years of effort between the
Department of Veterans Affairs and UB with the installation of the area's first PET
camera. The Buffalo VAMC and the Cummings Foundation were included in the
activities. The latter provided a $1 million grant that served to ensure the success of the
project. Dr. Joseph Prezio provided exemplary leadership for this project and organized
an outstanding scientific symposium.
The second event was the celebration of the lOth anniversary of
the Graduate Medical Dental Education Consortium of Buffalo
(GMDECB). The organization has become the institution for governance of graduate medical education in Western ew York and it is
membered by ll participating institutions- the medical and dental
schools and nine affiliated teaching hospitals. The GMDECB has
been instrumental in providing stronger training programs and in
developing new direction and new emphasis for graduate medical
education. The organization has committed to achieve a 50 percent
distribution of trainees to the primary care specialties of family
medicine, internal medicine and pediatrics over the next few years. It has also become a
model that might serve to provide some guidance to national health care leaders as new
initiatives in health care reform develop. Dr. Michael oe, executive vice president and
medical director at The Buffalo General Hospital and program director of the preventive
medicine training program, in particular, has provided extraordinary leadership to the
GMDECB effort.
Sincerely,

John aughton, M.D.
Vice President for Clinical Affairs

TEACHING HOSPITALS AND
LIAISONS

Batavia VA Medical Center

Arlene Kelly
The Buffalo General Hospaal
Michael Shaw
Buffalo VA Medical Center
The Children's Hospital of Buffalo
Erie County Medical Center
Mercy Hospital
Millard Fillmore Hospitals
Fran I• Sava
Roswell Park Cancer Institute
Sisters of Charity Hospital
Dennis McCarthy
~ The State University of ew York at
Buffalo

Buffalo Physician IS published quarterly
by the State University of New York at
Buffalo School of Medicine and
Biomedical Sciences and the Office of
Publications. It 1ssent, free of charge, to
alumm, faculty, students, residents and
friends. The staff reserves the nght to
edit all copy and submissions accepted
for publication.
Address questions, comments and
submissions to : Editor, Buffalo
Physician, State University of ewYork
at Buffalo, Umversity Pubhcauons, 136
Crofts Hall, Buffalo, New York 14260

Send address changes to: Buffalo Physician,
146 CFS Addition, 3435 Mam Street,
Buffalo, New York 14214

Dear Fellow Alumni,

T

he beginning of anew academic year brings another cycle of activities for the Medical
Alumm AssocJatwn, with the goal of enriching the experiences of medical students,
house officers and alumni. We have greeted the incoming house staff and will shortly
sponsor another one-day session on "Prep for Practice," a practical practice
management introduction (recognizing the current uncertainties of future practice). We have welcomed the entering freshman medical class and during the academic
year will continue our support for a variety of student projects. In particular, the Alumm
Association will continue to organize three sessions, with presentations by community physicians devoted to differing types of medical
practice.
In September, the annual award honoring an outstanding alumnus was presented to Dr. William Balistreri, Class of 1970. Dr.
Balistreri is professor of pediatrics and medicine at the University of
Cincinnati College of Medicine and is an internationally recognized
pediatric hepatologist. We are especially pleased that Dr. Balistreri
participated in the teaching program at Children's Hospital; his
participation provided a wonderful opportunity for our medical
students, house officers and faculty to benefit from his presence.
Alumni receptions have been planned in neighboring Rochester and at several
national medical meetings. Local alumni again will be guests at our annual reception.
Your support for these most worthwhile activities is needed and appreciated.
.,,,,,.,,d,,
~

(aver: The photograph of Dr. Joseph
Prez10 was created by Collignot0arosz
LTD.

Robert E. Reisman, M.D. '5 6

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1993

IJ Research
IJ Hospital News
IJ The Center for Positron Emission Tomography e
"Then and Now" heralds the
Sesquicentennial. Page 29.

Dedicated to patient care, research and education.

m

10 Years of Cooperation over Competition e

The Graduate Medical Dental
Education Consortium of Buffalo
celebrates a decade of progress.

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Alumni
Graduate Education
Medical School
Classnotes

ASpoonful of Humor

11

Shake and Bake." Page 3.

*

[~il~ren' s
~ospital ~egins
~W uaccine

trials. ~agel.

11

ln Sickness and in Health." Page 28.

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Study subjects must have well-documented HIV infection but no symptoms of
HIV disease other than swollen lymph
glands or a mildly swollen liver or spleen.
Subjects also cannot have received any
anti-retroviral or immune-regulating drugs
within one month before their entry into
the study.
The Centers for Disease Control and
Prevention estimates 10,000 children in
the U .5. are infected with HIV. By the end
of the decade, the World Health Organization projects 10 million children will be
infected worldwide.
For more information about trial sites
or eligibility for enrollment, call the AID
Clinical Trials Information Service at 1800-TRIALSA, or call the PACT program
+
at Children's Hospital at 878-7908.

Children'sHospital selected for
experimental HIV vaccine trials
he Parents and Children's Together
(PACT) program at The Children's
Hospital of Buffalo is one of 12 sites
nationwide coordinating the ationallnstitutes' of Health first trial
of experimental HlV vaccines for
children.
"This trial is the first step in developing
a vaccine thatmaypreventordelaydisease
progression in children with HIV," notes
Cynthia zelc Kelly, M.D., director of the
pediatric AIDS program at Children's.
The study, which will compare the safety
of three experimental vaccines in 90 children, will enroll children between the ages
of one month and 12 years. At least half of
the children in the nationwide trial will be
two years of age or younger to enable a
comparison of the immune responses of
the younger and older participants.

Tying cholesterol testing to being
overweight may miss many at risk

Children's Hospital will help (Oordinate HIV va((ine trials.

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electing patients for cholesterol testing merely because
they are overweight is a poor
practice and may cause primary care physicians to miss
many high-risk people, a University at Buffalo study has found.
Neither weight nor body mass
index is associated with high cholesterol levels, suggesting that
screening should be offered without regard to weight, the study by
Barbara A. Majeroni,M.D., UBclinical assistant professor of family
medicine, determined. The study
was reported in The journal of Family Practice.
Majeroni reviewed the charts of
604 patients selected randomly from
her group practice; 196 of the patients had had their cholesterol levels determined.
Results showed a trend toward
less screening of people with a low
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Neither weight nor body mass index is assodated
with high (holesterol, the study found.
body mass index and more screening of
persons with a higher body mass index.
But the overweight people were no more
likely to have high cholesterol levels than
+
patients who weren't overweight.
BY

LOIS

BAKER

Nitric oxide treatment used for
persistent pulmonary hypertension
esearch at The Children's Hospital of
Buffalo with nitric oxide ( 0) may
pave the way for breakthroughs in
the treatment of persistent pulmonary hypertension in newborns.
" itric oxide research and therapy
may be the biggest step yet in the treatment
of persistent pulmonary hypertension,"
said Frederick Morin, M.D., UB associate
professor of pediatrics and division chief
of neonatology at Children's Hospital.
Treatment with 0 selectively dilates
the vessels to the lungs-increasing blood
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flow to the lungs and oxygen in the blood
within minutes - to stabilize the newborn.
Preliminary indications show that 0
treatment may be a much less expensive
and less risky treatment than extracorporeal membrane oxygenation - a fairly
new treatment form itself.
itric oxide treatment is being conducted on a trial basis for persistent pulmonary hypertension at Children's Hospital and four other medical centers across
+
the country.

New software will allow rapid
solution of complex molecules
cientists who design new drugs will
soon have at their disposal an extremely fast software package that
solves complex molecular structures
on a workstation, sometimes in minutes or hours.
The new software, called "Shake and
Bake," was developed by researchers at
the University at Buffalo and the Medical
Foundation ofBuffalo, and has developed
from basic research to viable product in
less than one year.
Led by
obel Laureate Herbert
Hauptman, the research team invited researchers doing rational drug design and
other work involving complex molecular
structures to sign up for an initial test
phase of the package during the summer.
General distribution is scheduled for the
fall.
"'Shake and Bake' will solve structures
that no one's been able to solve,'' said Russ
Miller, Ph.D., UB computer science professor and a member of the research team.
The software is the first that can routinely
solve structures of up to 300 to 400 atoms
if high-quality X-ray data are available.
The user-friendly, menu-driven package has taken only hours or days to solve

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Bake" can
solve complex
molecular
structures in
minutes or hours.
very complicated structures, including
structures that previously took more than
a decade to solve using other methods,
and others that had previously been unsolved.
Two versions of the software are available: one that runs on aU IX workstation
and one on a massively parallel Thinking
Machines CM-5 supercomputer.
+
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ELLEN

G

OLDBAUM

Method for synthesizing promising
new cancer treatment developed
niversity at Buffalo scientists have
removed a major obstacle to the
synthesis of an extremely promising cancer treatment that would inhibit uncontrolled cell division.
A paper that describes the new
approach to synthesizing potential protein kinase inhibitors, which is orders of
magnitude faster than previous ones, was
published in the May issue of The journal
of Biological Chemistry.

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"This will allow scientists to survey a
much wider range of candidate inhibitors
in a much shorter amount of time, including compounds that were just not synthetically accessible before," said David
Lawrence, Ph.D., UB associate professor
of chemistry, who led the research team.
Protein kinase inhibitors, which inhibit
the formation of the enzyme kinase that
signals cells to divide, are generally recognized as potentially "a very novel family of
chemotherapeutic agents," Lawrence said.
Synthesizing such compounds in the
lab, however, has been a difficult hurdle
for scientists to overcome.
Because of this, the UB scientists focused on developing protein kinase substrates rather than inhibitors. Both substances bind to their target enzymes substrates temporarily and inhibitors permanently - to inactivate the enzyme.
Lawrence explained that focusing on substrates enabled the team to rapidly determine the types of chemical structures the
enzyme would recognize.
Lawrence said that both substrates and
inhibitors must contain a specific amino
acid within a peptide- a string of amino
acids - that is recognized by the target
enzyme, to be effective. He added it was
generally accepted that the key amino acid
had to be contained within the string,
rather than on the end because this was
observed in natural proteins.
"Because the critical component is often
very chemically sensitive, the process of
attaching other amino acids to it often
triggers unwanted chemical reactions
which can ruin the critical compound,';
Lawrence said.
In what he described as "an act of desperation," the UB team attached the key
component at the very end of the chain of
amino acids.
"To our amazement, we found that such
compounds served as extremely efficient
substrates for enzymes,'' he said.
+
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GOLDBAUM

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able, as well.
The program is
closely affiliated with
Roswell Park Cancer
Institute and The
Children's Hospital of
Buffalo as well as other
area health care facilities that offer pediatric services. It is one of
only a few pediatric
z
hospice programs in
3
~
the country that main§
tains swing beds in an
~
acute care hospital.
Hospice Buffalo begins its home-based, comprehensive pediatric service.
For more information or patient referral, call838-4438, Ext.
219.
+

.

Comprehensive pediatric service
established by Hospice Buffalo

ECMC achieves lowest trauma
mortality in New York State

ECMC had 3,386 trauma admissions over
the past 18 months with a total mortality
rate under 2 percent- the lowest mortality rate in the state for a regional trauma
center. For treatment of adolescents 10 to
15 years old admitted for trauma, the
hospital achieved a 0 percent mortality
rate.
" o one component of the trauma system, whether it be police, fire, medical
care or pre-hospital community care, can
exist separately," said ECMC administrator Thomas Faith. "The truly regional and
comprehensive nature of theW estern ew
York Trauma System is a model that everyone who is associated with it can be
proud of."
+

Buffalo General'sLancaster
Alcoholism Clinic extends hours

ospice Buffalo has established "The
Carousel Program for Children and
Families," a comprehensive pediatrie County Medical Center's Regional
he Buffalo General Hospital's
ric service for children and adolesTrauma Center has the lowest reLancaster
outpatient alcoholism
cents with life-threatening illnesses
gional mortality statistics in the state,
clinic
has
extended
its hours of opand their families.
and with the exception of the region
eration.
The interdisciplinary home-based prothat encompasses ew York City
Alcoholism Outpatient Services,
gram provides coordinated, comprehenand Long Island, the most trauma
11
West Main Street, Lancaster, is
sive care under the direction of the child's
patients.
open
from
9 a.m. to 8 p.m., Monday
physician, according to Eva Rubinstein,
According to statistics compiled by the through Thursday, and from 9 a.m. to 5
R. . , J.D., director of pediatrics for Hosew York State Department of Health, p.m. on Friday.
pice Buffalo. Caregivers work closely with
Services include
Robert Milch, M.D., Hospice medical di- ~
assessment
to derector, other area physicians, nurses and ~
termine if an alcoallied health care professionals to meet the *
hol
or drug probphysical, psycho-social and emotional ~
lem
exists; indineeds of children and their families. Chilvidual,
group and
dren are not required to give up curative
family
counseling;
therapy or have a limited prognosis to be
education and readmitted into the program.
lapse intervention
The Carousel Program offers homecounseling, as well
based pediatric skilled nurses, medical
as services for adult
social workers, child life specialists, art
children ofalcoholspecialists, music therapists, speech theraics.
pists, occupational therapists, pastoral
For more inforcaregivers, volunteers, bereavement counmation,
call 681selors, dietitians and home health aides.
4957.
+
High-tech home care services are avail- ECMC's Trauma Center mortality rate was less than 2 percent.

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Buffalo General opens East Side
adult ambulatmy care program

Amsterdam named director of
laboratory medicine at ECMC
aniel Amsterdam, Ph.D., professor
of microbiology and associate professor of medicine, has been appointed director of the department
oflaboratorymedicineat Erie County
Medical Center.
Previously, he was
director of clinical
microbiolgy and im.....
munology there.
Amsterdam
earned his doctorate
,.,,;)!'•
..
.. ·.'...:·'
from ewYorkUni"'~
versity. Before joiningECMC,heheaded
the human cell biology program at the
euroscience Center of the Kingsbrook
jewish Medical Center and was on the
faculties of Long Island University and the
Mount Sinai School of Medicine.
Amsterdam is a member of the American Association for the Advancement of
Science, the American Association of Pathologists, the American Society for Cell
Biology, the American Society for Microbiology and a fellow of the American
Academy of Microbiology, the American
Association for the Advancement of Science and the Infectious Diseases Society
of America.
+

Children'sHospital appoints new
director of pediatric surgery

~ ,. ~

ichard Azizkhan, M.D., has been
appointed surgeon-in-chief and director of the department of pediatric surgery at The Children's Hospital of Buffalo and professor of surgery and pediatrics at the School of
Medicine and Biomedical Sciences.
Azizkhan was formerly associate professor of surgery and chief of pediatric
surgery at the University of orth Carolina at Chapel Hill School of Medicine.
He earned his medical degree from the
Milton S. Hershey Center of Pennsylvania
State University College of Medicine and
completed a residency in general surgery
at the University of Virginia Medical Center. Azizkhan did his pediatric surgical
training at johns Hopkins University.
Board certified by the American Board
of Surgery in general surgery, pediatric
surgery and surgical critical care, Azizkhan
is a member of the American College of
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Surgeons, the American Pediatric
Surgical Association, the Association
for Academic Surgery, the Society of
University Surgeons,
the American Association for Surgery
of Trauma, the American Medical Association and the American Academy of Pediatrics.
+

he Buffalo General Hospital has
opened an adult primary care center
on Buffalo's East Side.
The 1490 jefferson Health Services at 1490 jefferson Avenue will
offer general medical care, health
screenings, podiatry care, nutritional counseling, health education and wellness programs and social work counseling for
people who require referrals to social and
human service agencies.
The new facility includes five examination rooms on the first l1oor of the 1490
Enterprises Community Center, where it
is housed.
All private insurance as well as Medicaid and Medicare are accepted.
+

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Chairman of pathology appointed
at Roswell Park Cancer Institute
ohn]. Brooks, M.D., has been appointed chairman of the department
of pathology at Roswell Park Cancer
Institute and professor and vice
chairman of the department of pathology at UB.
A graduate of jefferson Medical College, Thomas jefferson University, Philadelphia, Brooks completed his residency
in pathology at the Hospital of the University of _Pennsylvania School of Medicine, where he was chief resident and
assistant instructor of pathology. He was
associate director of the section of surgical pathology, director of the immunohistochemistry laboratory and professor of
pathology and laboratory medicine at the
Hospital and School of Medicine at the
University ofPennsylvania, Philadelphia.
In 1987, he served as a visiting professor
with honorary clinical status at the Royal
Marsden Hospital and Institute for Cancer Research, London and Surrey, England.
Brooks also has subspecialty training in
hematopathology, soft tissue pathology,
immunohistochemistry, in situ hybridization and the ultrastructure, cytogenetics and growth of soft tissue tumors.
The author of more than 100 original
scientific papers and 50 scientific abstracts,
editorials, reviews, book chapters and
letters, Brooks holds editorial positions
on the journals Surgical Pathology, Modem
Pathology and Applied Immunohistopathology. He is a reviewer for the journals Cancer, Ameri-

can journal of Pathology, Cancer Research and the European journal of
Cancer Research
and Clinical Oncology.
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Cooperative efforts between UB and the

Department of Veterans Affairs become a reality

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�On May 14, 1993, the University at Buffalo joined a select group
not awarded its $3.4 million federal funding package until1988.
"We didn't get it in the first round, but we did in the second,"
of nuclear medicine centers of excellence when it formally
dedicated its $12 million Center for Positron Emission
aughton says of the VA grants awarded on an annual basis. The
Tomography- one of the most advanced in the country and
grant was one of only four high-technology projects the federal
one of the few with clinical, research and educational applicabody awarded that fiscal year.
But with minimum PET startup costs estimated at between
tions.
The multidisciplinary center, which integrates medical spe$7 and $10 million, the federal grant was only a start for UB's
cialties and subspecialties within its three functions , has been
ambitious project.
the result of collaborative efforts between the federal and state
Funding ultimately came from diverse sources: $1.6 million
governments and private foundations and corporations since its
from UB itself, 6 million from ew York State, $1 million from
the james H. Cummings Foundation in the form of a contribuinception. Indeed, even physically, the center consists of two
distinct entities- UB's Parker Hall, the site of the cyclotron, and
tion to the University at Buffalo Foundation's "Pathways to
Greatness Campaign" and the VA award.
the Buffalo VA Medical Center, 3,000 feet across the street,
PET technology is considered one of the most advanced in
where the PET scanner itself is housed - connected by an
underground pneumatic tube system.
medical imaging, distilled from a number of scientific disciThe center's origins date back to the mid-1980s,
\l ucE sMA
plines. It enables the visualization and quantification
VI 11
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when congressional legislation made it possible
c:, \\\
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of complex physwlogiCal processes on a chemifor certain grants to be used to fund both ...,~'\
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Department ofVeterans Affairs facilities and ,$'•
~ physiologically compatible positron-emitthe communities they serve to develop and ~
~.,., ting radionuclides synthesized into phar~ maceutical drugs that are administered
share scarce medical resources. The UB- ~
VA PET center accepts both veterans and :
~ to patients and read by a scanner. The
non-veterans.
~
~ infonnation the scanner reads is then
"The VA was instrumental in the de- "'
~ fed into a computer to produce three%!
velopment of this technology," says john ~
~ dimensional images of physiological proaughton, M.D., vice president for clini- ~
cesses.
cal affairs and dean ofUB's School ofMedi- ~
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PET technology uses radioactive nu?'
cine and Biomedical Sciences. "There are ,;
c,
elides of elements commonly found in the
several PETS in the country located in VAs. "
body, such as oxygen, nitrogen and carbon,
The PET center now serves four to six patients
that are administered to the patient. Because they
each week. "A fair number of those referrals are from
are physiologically compatible, the PET radionuclides
Rochester," aughton says.
actually follow true physiological and metabolic processes,
Cooperation between the different entities that comprise
rather than mimic biological pathways as other nuclear mediUB's PET center has been the byword from the start of the
cine imaging technology tracers do.
PET imaging produces images of the functioning of the body,
project.
augh ton praised the joint relationship between the univerrather than its structure, as more traditional forms of medical
sity and the Buffalo VAMC in both the ownership and manageimaging technology- CT scanning, for instance- do.
The technology, which can afford physicians a cellular view
ment of the PET facility.
"The cooperative venture allows the VA to do something it
of biochemical processes, shows promise in a number of disciplines and applications, among them, cardiology, neurology,
couldn't do itself and the SU Y system to do something it
couldn't do by itself," says Alan Lockwood, M.D. , director of
psychiatry and oncology.
The key to UB's successful PET center, according to aughton,
PET center operations for the VA and UB professor of neurology
and nuclear medicine. "This is a very rich intellectual environwas "developing the cyclotron"- the specially designed electromagnetic device that accelerates charged particles or ionized
ment for something like this to take place in. UB is the flagship
atoms to very high velocities. The high-speed particles then
institution of the SU Y system and the Buffalo VA Medical
collide into targets - physiologic elements- to produce the
Center is one of the major VA hospitals in the country."
radionuclides.
"There was no space at the VA for the cyclotron," aughton
says of the arrangement. "So we used a bay in Parker Hall to
UB's cyclotron is one of the more advanced in the country.
Manufactured by the Belgian firm , Ion Beams Application, it is
house it.
"Parker Hall not only houses the cyclotron now, but it serves
the largest and most powerful of its type manufactured today.
as a base for the nuclear medicine department. The arrangement
From its specially designed bay in Parker Hall, it manufactures
has enabled us to centralize that department. "
radionuclides that are converted to radiopharmaceuticals by the
UB entered the competition for PET grants in 1987, but was
chemistry function of the nuclear medicine department in

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�Parker and then transported via pneumatic tubes to the PET
scanner suite at the VA.
It takes the radio pharmaceuticals- many with a half-life of
slightly more than two minutes, according to Lockwood- 80
to 90 seconds to travel the 3,000-foot distance.
The scanner portion of the center has been in operation since
October 1991; before UB's cyclotron went on-line during the
summer, the center purchased radionuclides from Hamilton,
Ontario, a ugh ton says. ow, the university is in a position to
supply some of the "longer" short-lived radionuclides to other
PET centers, he adds. UB's PET center is the only one within a
150-mile radius; it is one of only four in the state and one of two
approved for use in patient care.
PET technology has been in existence since the mid-1970s,
according to joseph Prezio, M.D., chair of UB's department of
nuclear medicine, director of the PET center and one of the
driving forces behind the university's entree into PET technology. "But it was so technically poor and cumbersome and
atrociously expensive, no one could get involved except for a
few well-financed research centers," he explains.
"As the equipment matured," he continues, "the cost, though
still prohibitive, got a little better.
"And," he explains, "there were clinical reasons to continue."
Those clinical reasons include hopes for improved treatment
outcomes and better understanding of a number of diseases and
conditions, including epilepsy, coronary artery disease, schizophrenia, Alzheimer's disease, Parkinsonism, brain tumors and
cancer.
PET imaging in cardiology detects coronary artery disease
earlier and with greater sensitivity than more traditional diagnostic procedures, often precluding the need for cardiac
catheterization and other procedures that involve patient risk.
At the VA Medical Center, patients with ischemic coronary
artery diseases- about 100 so far- are scanned to determine
whether an area of the heart with poor blood flow is still alive
and capable of benefiting from certain treatments or dead and
not capable, Lockwood says.
"Current tests available primarily measure flow . We help sort
out the difference between low-flow live muscle and low-flow

An underground pneumatic tube connects the cyclotron boy in Porker
Hall to the PET scanner suite at the Buffalo VA Medical Center. The tube
system provides high-speed transfer of rodiophormoceuticols for use in
medical imaging. The rodiophormoceuticols- some with a half-life of
just over two minutes - travel the 3,000-foot route in 80 to 90 seconds.

PET Scanner Suite
Buffalo VA Medical Center

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�dead muscle to determine the best candidates for bypass or
angioplasty and to avoid expensive and risky procedures," he
adds.
The technology is revolutionizing the way patients are
chosen for angioplasty and coronary bypass surgery or medical
treatment.
The technology is also revolutionizing oncology treatment
decisions-enablingphysicians to evaluate the effectiveness of
chemotherapy within a matter of days rather than months.
At the VA, it is also being used to successfully pinpoint the
site of electrical outbursts in the brains of epileptics as part of
presurgical evaluations to determine whether seizures emanate
from a single spot in the brain. "Around half the patients are
seizure-free after surgery," Lockwood says. "And a substantial
portion of the other half get substantial improvement. lt makes
an enormous positive impact on the patient's life. "
And although there are no clinical applications in psychiatry
yet, UB's center already has garnered research awards with
strong clinical applications, among them , grants to look at brain
injury after minimal trauma and study brain pattern abnormalities after severe liver disease. The minimal brain trauma study,
Lockwood says, involves collaborative work between the VA
and UB's departments of psychiatry, neurology, internal medicine, nuclear medicine and emergency medicine at Erie County
Medical Center.
Lockwood says the PET center is beginning clinical studies
of patients with colorectal cancer to detect recurrences. Other
research involves collaborations with the university's linguistics department to try to determine which areas of the brain are
involved with specific functions of speech.
In addition to its clinical and research applications, UB's PET
center is the first comprehensive training center for PET
imaging in the United States, thanks to a three-year, $450,000
grant from Siemens H. G. , a major supplier of nuclear imaging
equipment.
The center is equipped to train the range of personnel
needed to operate a fully functioning PET center - from the
technicians who assist the chemists to the physicians who
specialize in nuclear medicine. It is organized around four

Winspear Ave.

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Porker Hall
University at Buffalo South
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major training groups: technicians, radiochemists, nuclear physicists and physicians.
"The problem throughout the U.S. and, probably the world,"
Prezio says, "is that training for PET has not been organized
appropriately, or in enough depth, so that you can end someone to one site and have them come back seasoned and trained.
Siemens liked what we were doing here. They were looking for
someone willing to put the effort into it.
"Our goal from the beginning, in addition to establishing the
PET imaging center for research and clinical use, was to set up
a national educational program that would be unrivaled in the
United States."
In addition to that Siemens grant, the Buffalo VA Medical
Center will receive more than $150,000 from the corporation to
develop computer software for the PET scanner.
Two new software modules will be developed: one, with both
research and clinical care applications, will compute blood flow;
the other will describe metabolism in the brain using mathematical modeling of biochemical reactions.
"Right now there is no software in our computer system that
enables a user to measure blood flow ," says Lockwood. 'This
will expand the capability for existing and future PET systems,"
he adds.
The grant was developed through a Cooperative Research
and Development Agreement. The agreement, which falls under
the auspices of the federal Technology Transfer Act of 1986,
allows both federal and private corporations to work together to
develop new technology.It is only the second time in VA history
such an agreement has been reached.
"This is an example of a new trend in funding of medical
research where there's cooperation between public and private
sectors," Lockwood says. "This will be an increasingly important aspect to funding future research of all types. "
On the downside, "PET studies are expensive [currently
running over $2,000 per procedure] and not generally covered
by health insurance in this country. In Buffalo, however,"
aughton says, "payment arrangements are made on a case-bycase basis. Many of the area's major third-party payers have
negotiated rates to cover the studies."
To ensure coverage, Lockwood says that patients at the PET
center are carefully screened to meet certain criteria. "We study
patients only with specific indications for the procedure, rather
than as an open-ended diagnostic procedure.
"This is a very deliberate step we've taken because of our
commiunent to provide cost-effective services to the public," he
notes.
"We request reimbursements only for procedures judged
likely to be cost-effective. And because of this, we've had good
relationships with insurers in this area.
"After all, insurance companies will want to pay $2,400 for a
study if it will save them $40,000 down the road."
And although neither Medicaid nor Medicare reimburse for
PET scans, national efforts are underway to change that.
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PET center dedication culminates two decades of
planning and development for the future

oe Prezio, M.D.'s singular vision of making the
University at Buffalo a major force in nuclear
imaging became a reality on May 14, 1993, when
the University formally dedicated its Center for
Positron Emission Tomography (PET) that is one
of the most advanced in the country.
It was a vision that began in the mid-1960s and
took root two decades later when congressional
legislation made it possible to award grants that
would aid both federal Veterans Affairs hospitals
and the local communities they served. And it was
a vision that Prezio -as both chairman since 1985
and professor of nuclear medicine - is largely
responsible for nurturing.
According to john Naughton, M.D. , vice president for
clinical affairs and dean of the School of Medicine and
Biomedical Sciences, Prezio has helped build a department
"always strong in the research arena and with a fine clinical
presence."
Prezio came to UB first as an internal medicine resident
in 1959 and then as a clinical assistant professor and
assistant director for medical education at Mercy Hospital
in 1964. Over the next nearly 30 years he has served the
university, he has seen both the department of nuclear
medicine and the specialty itself grow and expand at the
undergraduate and graduate levels as well as in its clinical
and research functions.
Prezio's love of nuclear medicine and the city in which
he's realized his dream began rather circuitously with a
rotating internship in internal medicine at Mercy Hospital.
The Georgetown University Medical School cum laude
graduate's strong interest in endocrinology- he eventually completed both a clinical and research fellowship in the
field at Georgetown - developed into an even stronger
interest in nuclear medicine as Prezio used radioactive
iodine to treat thyroid patients.

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�programs filled by international medical school graduates is
about 60. Since 1985, UB's national graduate enrollment
average has been greater than 90 percent.
Part of what makes UB's nuclear medicine residency
programs so attractive is that some combine nuclear medicine with another specialty- such as internal medicine and
radiology- to allow graduates to get both boards in a shorter
period of time than they would if they completed two separate
residencies.
"The programs are so successful," Prezio says, "that we're
now offering a five-year program with the PET and neurology
and psychiatry. That's five years versus six or seven years.
And both the job market potential and academic career
potential are outstanding.
"We're the only university in the country offering the
combined programs- except for a smaller, not-as-mature
program at the University of orth Carolina."
Prezio has also focused on major educational programs to
increase community awareness and extend the university's
concerns about the quality of nuclear medicine.
"We want to expand our educational services beyond
Western New York to become a national training site- not
only for conventional nuclear medicine, but especially for
PET training.
"We've just completed a training program for endocrinologists to familiarize themselves with radiation safety
techniques in their practice. We want to expand on that. "
The PET center figures heavily in Prezio's plans for the
future- he wants to establish it as a major research center,
and is well on the way to accomplishing that goal already with
the acquisition of grants to use PET technology to look at
brain injury after minimal trauma and brain pattern abnormalities with severe liver disease.
Prezio also wants to develop and enhance the department's
attractiveness to industry. "I want to use the PET center and
department as a resource and evaluation site for new drugs. "
Taward this end, Prezio is recruiting an expert in nuclear
pharmacokinetics.
Prezio's final goal- at least for the present- is to further
expand the multidisciplinary approach the department of
nuclear medicine has taken in the past 10 years.
"We want to continue to work closely with neurology and
psychiatry to assist in research where PET technology can be
applied. We want to bring all these research activities into this
department. "
Prezio credits Michael Cohen, M.D. and Murray Morphy,
M.D. -chairs of neurology and psychiatry respectivelyfor spearheading the effort and for the successes they have
already achieved. "They took a 'what's good for everybody'
attitude rather than 'what's good for me' attitude and they
deserve a lot of credit.
+
"We led the way in these jawboning techniques,'' he says.

"That's how it all
started," he relates.
In fact , Prezio merged
those interests when he
started the clinical radioisotope program at the South Buffalo hospital nearly three
decades ago.
At that time, nuclear medicine was in its infancy- its first
identification as a specialty, in fact, was in the late 1950sbefore the technology revolution that saw its knowledge base
expand almost exponentially.
"As the field became more complex, with the development
of new imaging technology and new radiopharmaceuticals, it
came into its own," Prezio said. "The idea to start a separate
specialty," he adds, "was born in Buffalo, with Dr. Merrill Beader
at Roswell Park Cancer Institute. He worked feverishly and with
considerable aplomb to establish a forn1al residency program in
1971. It was the first in the country. In 1972 the boards were
offered for the first time. "
In 1972, nuclear medicine's technology consisted pretty much of
a "scanner device and early scintillation gamma camera,'' according
to Prezio. Applications consisted of lung, bone, thyroid and
brain- the cardiac applications that are a mainstay today had
not yet become a reality. And at the time, both the technology and
its applications were directed at in1aging.
"The direction today,'' Prezio explains, "is not just imaging,
but the functional analysis of actual biochemical processes.
"The next step is the cellular processes. We can look at these
with the PET."
And with UB's sophisticated new PET center- one of the
few in the country with the capacity for both patient care and
research- the department of nuclear medicine is positioned to
become a national leader in both.
Under Prezio's stewardship, the department has accomplished several goals.
"The major thing," Prezio says, "is the centralization of the
department from Diefendorf Annex. " Its recent consolidation
to Parker Hall "is the first time in its history that it is totally
centralized in one place.
"All major educational activities for training medical students, technicians, nuclear medicine residents , are all here in
Parker Hall.
"Our grand rounds," he adds, "draw 90 people. They are
always very well attended. We draw physicians and technicians
from Rochester, Hamilton- the whole Western ew York
area. It [the centralization and resulting consolidation] is an
outstanding success.
"And psychologically, it's better," he says, noting "neutral
territory. "
Making the nuclear medicine programs more attractive to
American graduates has been another accomplishment.
ationally, the percentage of nuclear medicine residency

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�The
Consortium's
structure
emphasizes the goal of improving educational quality, not
meddling in the member hospitals' operations, and giving the
members on
equal voice in
decisions.

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NECESSITY, THE UNIVER-

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TEACH I G HOSPITALS ARE Fl
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AS THEY

JVERSARY OF THEIR I STITUTIONAL

ALLIANCE.
Through the Graduate Medical Dental tion of American Medical Colleges.
"People are coming and looking at
Education Consortium of Buffalo, the assortment of residency programs scattered what we're doing with the Consortium,"
among area hospitals has been brought said William D. Pike, president of the
under an organizational umbrella, giving Western ew York Hospital Association.
the university greater control over gradu- "It is unique and something we should be
ate medical education without threaten- proud of."
aughton is
ing hospital auclearly proud of the
tonomy. The arrangeconsortium he was
ment has fostered
instrumental
in
greater cooperation at
"If I had to describe it in
forming 10 years
a time of increasingly
ago. "We're probstrained finances, and
a word, I'd say
ably the most soit has taken on some
phisticated and
of the thornier policy
'consensusbuilding .' I
complex consorquestions in health
tium that exists in
care, such as the need
would say no one has lost
the country," he
to tum out more prisaid. "I don't know
mary care physicians.
"There have been
that we necessarily
any autonomy."
a lot of positive
are the model, but
outcomes ," john
we are a model."
Richard Braun, vice
aughton , M.D. , asSitting back in
sociate vice president
shirt-sleeves behind
president of finance and
for clinical services
his wide desk,
and dean of the mediaughton recalled
chief financial officer of
cal school, said simthat it wasn't always
ply.
easy. Some resiAnd witl1 the nadencyprograms had
The Buffalo General
tion bracing for major
to be reorganized,
upheavals in health
with responsibilHospital
care and medical eduities and resources
cation, the Consorshifted among diftium is also being
ferent hospitals.
viewed as a model.
And, he notes, bu"When people talk about GME con- reaucratic turf battles haven't been comsortia, they all talk about Buffalo," said pletely relegated to history.
joyce Kelly, Ph.D., associate vice presi"It'll lead to some testiness from time to
dent for clinical services with the Associa- time," he said. "It'll lead to some issues.

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But it works out."
In fact, Naughton said, he was surprised there weren't more problems in
bringing the university's teaching hospitals together. "Amazingly enough, given
the magnitude of it, the difficulties were
relatively modest," he said. "The main
difficulties were in visualizing the needs
and in bringing everybody into it so they
filled their proper roles. "
The goals behind the Consortium are
better education for residents and better
coordination among the participating institutions.
"Most university medical centers are
single centers that report back to one
university," said Richard Braun, vice president of finance and chief financial officer
of The Buffalo General Hospital. "What
we have is a consortium of eight hospitals
that divvy up the teaching."
The idea for the Consortium came in
the early 1980s when the Accreditation
Council for Graduate Medical Education
issued new guidelines requiring greater
institutional management of residency
programs. At the time there was little
coordination between the Buffalo programs, with some controlled by the university and some by the hospitals - The
Buffalo General Hospital, The Children's
Hospital ofBuffalo, Millard Fillmore Hospitals, Erie County Medical Center, Sisters
of Charity Hospital, Buffalo VA Medical
Center, Mercy Hospital and Roswell Park
Cancer Institute.
UB was not the only medical school in
the nation without its own medical center.
But even among schools relying on community hospitals, the UB-affiliated residency programs were notably scattered,
said Michael F. oe, M.D. ,BGH executive
vice president and medical director.
"We did not have the university or a
university hospital identified as the sponsor of the programs," recalled oe, who
worked with Naughton to forn1 the Consortium. "We had multiple hospitals identified
as the sponsor of individual programs."

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oe described the situation as "fragmentation to the extreme." In some cases, he said,
program directors found themselvesjuggling
the conflicting interests of several hospitals
involved in the same program.
"The hospitals each had their own house
staff, their own payroll and benefit package for the residents. There was no uniformityeveninthatarea," headded. " ordid
we have any common operating policies
that applied across the entire system."
David M. Crossland, M.D. , chairman
of the Consortium's residents committee,
agreed. "There was no organization. They
competed with one another and didn't
trust one another," he said of the hospitals. "Residency programs were as good or
as bad as the institution had them be."
Said aughton: "We had had prior to
that time a fair amount of problems with
the various accrediting bodies."
When the new ACGMErulescamealong,
"We had to respond," aughton said.
One of the first signs that the Consortium
would workcameearlyon, during seemingly
mundane discussions about designing a letterhead for Consortium stationery.
"There was always a little tension in the
communityaboutownershipoftheseresidencies," aughton recalled. "The question was, having made that bigjump, how
would we identify ourselves."
The dean said he was sure the hospitals
would balk at putting the medical school's
name anywhere prominent. He was happily mistaken.
"It was pretty clear that the hospital
directors thought the university should
have the lead in it," he said.
aughton credits several factors for
the Consortium's success, including its
design as a voluntary membership organization rather than a formal entity like a
corporation. The structure emphasized
the goal of improving educational quality,
not meddling in the member hospitals'
operations, and giving the members an
equal voice in decisions. "We weren't
merging anything," aughton said. "Ev-

ery institution was going to maintain its
integrity."
oe agreed. "I think our success in
establishment, as well as in the continued
operation of the [organizational] model
we decided upon, was first of all that it was
a fully participatory governance process,"
he said.

"You still have the individual tension,
obviously," Naughton said. "But the decisions are made collaboratively, not by any
single institution."
Members meet regularly and lines of
communication are kept open. The Consortium has three committees: administration, which includes deans, hospital

�heads and hospital medical directors; program directors, which includes university
department heads as well as the directors
of each residency program, and residents,
composed of elected representatives from
each program.
In addition, each committee elects a
representative to sit on the other two

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committees. "All of our dealings are public within the organization," oe said.
Program directors retain responsibility
over the residencies, and medical school
graduates still apply to individual residencies rather than the Consortium. But the
Consortium is the sponsoring institution,
and application forms and many other

PER

facets of the programs are now standardized.
"What we did was to externalize the
governance of all those programs from all
those hospitals to a central body," oe
said. Buffalo General CFO Braun said that
while the Consortium's course is clearly
set by aughton and the chief executive
officers of the member hospitals, its decisions are group efforts.
"If I had to describe it in a word, I'd say
'consensusbuilding,"' he said. "I would say
no one has lost any autonomy. "
Consortium members point to a number of achievements, including:
• Centralized record-keeping
Resident records were previously kept
by the individual teaching hospitals. Bringing them under one roof is more efficient
and has saved money, aughton said.
• Resident salaries
In the past, residents received different
salaries and benefits depending on which
program and hospital they were in. "Before
there were different arrangements between
hospitals ," aughton said.
Even residents in the same program
could receive different salaries if the program was spread over more than one hospital, oe said.
Consortium members spent a number
of years working on the problem. Along
the way they encountered complications
caused by the fact that some member hospitals- the VA and Erie County Medical
Center - are run by government, oe
said. "There were also union issues," he
added.
Two years ago the Consortium finally
succeeded in forming two independent
corporations to administer compensation
packages for medical and dental residents.
The corporations pool funds from the member hospitals and have eliminated most of
the variations in resident salaries and benefits.
• Orientation
There is now a single week-long orientation program for residents, which in-

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�eludes training in bedside manner and
certification in advanced life support.
• Grievance procedure
The establishment of a Consortium
procedure for appealing disciplinary actions has been a major stride for residents,
according to Crossland. "We've got much
better due process in place now," he said.
• Program reviews
The Consortium itself reviews residency programs for potential accreditation problems before the ACGME arrives
for its triennial checkup. "They do just as
good a job as the outside body," said M.
Luther Musselman, M.D., director of medical education at Millard Fillmore Hospitals.
any of the
Consortium's
initiatives, such
as pooling salaries and creating
a combined orientation program, represent efficiency
gains, said Diane Linskey-Hauser, executive director of the New York State Council on Graduate Medical Education. "There
are lots of economic reasons for doing
this," she said.
Crossland said the Consortium also
has worked to improve residency programs. Residents traditionally have been
burdened with heavy workloads that cut
into their time for study and research, he
said, adding, "That's beginning to change
and I'm impressed that they're serious
about it."
But some feel the Consortium's greatest achievement has been its willingness
to tackle wider medical issues, such as the
need for more primary care physicians.
"It's really seeking to address some of
these broader policy goals, well beyond
these day-to-day operational issues," said
Kelly.
The emphasis on turning out more
primary care physicians has become one
of the Consortium's top priorities. It has

set a goal of increasing the proportion of 13,000 residents, more than any other
residents in primary care specialties to half state and nearly double the number in
the total number of residents, and it has California. Buffalo itself has slightly more
also pledged to cap the resident popula- residents than does all of Kansas.
Buffalo's is neither the only nor the first
tion at 750 medical and 32 dental, roughly
teaching
hospital consortium in the nathe present number.
"That probably would be much more tion. The Association of American Medidifficult without some sort of consortia! cal Colleges tried to find out more about
them this year by sending questionnaires
effort," Braun said.
Any proposal to start a new residency to about 400 teaching hospitals, accordprogram in a field outside primary care is ing to Kelly. The survey identified about
met with heated debate at Consortium 40 different consortia around the country, though Kelly said
meetings, he added.
there are more, exMembers of the
plaining that the
Consortium are
survey's
purpose was
presently involved
to
learn
about
the orin a demonstration
"We're probably the most
not
to
ganizations,
project aimed at
count
them.
boosting the numsophisticated and complex
"Our preliminary
ber of residents in
findings
suggest that
the primary care spefor the most part the
consortium that exists in
cialties, the number
consortia
outside New
of minority physiYork
State
do not share
cians and the numthe country.
of
producing
the
goal
ber of physicians in
more
generalist
phyunderserved geoI
don't
know
that
w
e
sicians,
more
minorgraphic areas.
ity physicians and
Because of its efnecessarily
ore
more
physicians servforts, the Buffalo
ing underserved arConsortium is ateas," Kelly said.
the model, but
tracting national atThose other contention. "There are a
sortia
are geared more
lot of organizations
we ore a model."
toward
issues like resithat are interested in
dent
recruitment
and
trying to reform
John Naughton, M.D.,
coordinating
benefits,
medical education,"
she said. "Buffalo is
said Kelly. "Right
vice
president
fo
r
clinical
way ahead of everynowit'skindofheatbodyelse," she added.
ing up because as
The Buffalo Conaffairs
and
dean
of
the
folks are thinking of
sortium
has taken its
medical reform ,
cue
on
the broader
they're also thinking
School of Medicine and
social issues from the
ofmedical education
state, which has been
reform."
Biomedical Sciences
advocating greater use
ew York State
of consortia to implays a unique role
prove
medical trainin graduate medical
ing since the report of
education because
the state Commission
it has more than

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on Graduate Medical
care, underserved
Education in 1986.
populations and miThe Commission's
nority recruitment.
"We did not hove the
work led to creation
Another consorof the state Council
tium has been
on Graduate Medical
university or o university
formed around AlEducation, which has
bany Medical Colcontinued to push the
lege and Albany
hospital identified as the
consortium idea.
Medical Center, but
"The advantages
while its plan was apsponsor of the [residency]
would be that it alproved by the state
lows the opportunity
Council on GME
programs. We hod multiple
for regional planning
three years ago, the
and looking at sociorganization has
hospitals identified as the
etal needs rather than
been hampered by fiwhat the department
nancial problems
of medicine needs in
and it continues to
sponsor of individual
tenns ofstaffing," said
exist mostly on paLinskey-Hauser.
per.
programs. It was
In its Fourth AnAs time goes on,
nual Report, the Counhowever, and there
fragmentation to the
cil states: "Through
is more pressure for
consortia, medical
changes in medical
extreme. In some cases,
schools, their affilieducation and the
ated hospitals, and
health care system,
other teaching sites
there will be more
program directors found
can jointly define the
need for consortia.
educational needs of
"The point is that
themselves juggling the
residents and coordimedical schools and
nate the development
their teaching hospiconflicting interests of
of core curricula,
tals are going to have
placement of resito network better,"
several hospitals involved
dents and allocation
said aughton.
of educational re"A lot of coordisources in a way that
nation is going to be
in the some program."
is both efficient and
required among the
responsive to the
medical
schools and
Mi(hael F. Noe, M.D.,
needs of society."
the affiliated hospiSo far , the only
tals," agreed Linskeyexecutive vice president
other operating conHauser. "Right now,
sortium in the tate is
Buffalo is a very clear
and medical director of The
one organized by
model for how conew York Medical
sortia might be modCollege and nine afeled."
Buffalo General Hospital
filiated hospitals in
Kelly said there
the late 1980s. In adhave been consortia
dition to fostering
around since the
quality education, that consortium's goals 1960s and '70s, but now "they are being
also include more emphasis on primary created at an increasing rate."

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"The most common model for consortia is not the way it operates in Buffalo,"
she added.
Most consortia now follow the "integrated program" model, Kelly said. These
consortia are typically corporations set up
to take over the residency programs. The
member institutions give up their right to
sponsor programs, and instead, the corporation becomes the sponsor. Kelly pointed
to McGaw Medical Center at the orthwestern University School of Medicine.
Contrary to what the name implies,
McGraw Medical Center is not itself a
hospital, but a consortium covering several member hospitals.
Buffalo's consortium is an "independent" model, a less rigidly structured
umbrella organization that lets member
institutions retain a significant role in the
residency programs.
"There is no dominant hospital," said
Musselman.
"That's probably the biggest difference
between Buffalo and other consortia."

elly said that neither
structure is particularly better suited than
the other to pursue the
widersocietalgoals for
which consortia will
be needed, but the Buffalo model makes it
easier to get hospitals together in the first
place. "It means you can maintain your
independence," she said.
One manifestation of that independence
is in internal medicine, which is split into
two programs within the Consortium.
"Program A," with about 140 positions, is
based at Buffalo General Hospital, Erie
County Medical Center and the Buffalo
VA Medical Center. The smaller "Program B," with about 40 slots, is based at
Millard Fillmore.
Even though Millard Fillmore was a
Consortium member, it was reluctant to
give up its own internal medicine pro-

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�gram. "We didn't think it was good for
residents to have two months in five different hospitals," Musselman said. "They
finally agreed with us and allowed us to
keep our program."
Crossland said the Consortium's voluntary nature can be a disadvantage, limiting its ability to make changes. "It takes
a lot of time and persuasion," he said.
In general, however, the Consortium
has fostered greater cooperation among
its members.
"I think we generally feel now that in a
sense we have equal input into a decisionmaking process, that the unilateral decision-making that is sometimes not in the
best interest of the educational objectives
isnolongeraproblem," said oe. "Weare
equal participants in a planning process
that helps us assure the stability of our
educational relationships. There is no question that sometimes decisions that are
made don't go the way of one or more
hospitals, but on balance I think everyone
would agree the procedures set up have
brought more advantages than disadvantages, more wins than losses."
The primary care demonstration project
i one of the more notable examples of
cooperation through the Consortium.
Under the project- initiated by the Consortium and the medical school, six of the 1
Consortium hospitals, the ew York State
Department of Health, four private insurers and Medicaid- the hospitals involved
pool about 15 percent of the indirect medical education reimbursements they receive from the government and insurers.
The reimbursements are meant to help ,
compensate the hospitals for the costs of
their teaching programs, and the 15 percent they are pooling is money that would
otherwise have gone into the hospitals'
general budgets, Braun said.
The Consortium redistributes the
pooled funds , which amounted to about
750,000 last year, to the hospitals for use
in primary care training and other programs consistent with the demonstration

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project's goals.
The Consortium also makes it easier
for member institutions to respond to
changes, as they did several years ago with
a new state requirement involving resident credentialing. The Consortium
brought the proper people together to
establish a credentialing process, which

now includes a system for forwarding
records from one hospital to the next as
residents rotate, aughton said.
Crossland said that from the perspective of the residents themselves, the Consortium has been a "mixed bag." He said
it has helped by making salaries and benefits more unifom1, but he adds quickly

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that salaries should be higher.
"Overall in the ortheast, we're
in the lower 25 percent," he
said.
l n general, however,Crossland
said he is pleased with the
Consortium's goals and believes
its members are making a good
faith effort to improve educational programs.
But he said he worries that
financial problem could be an
obstacle. "The hospitals, I can't
overemphasize how much pressure they're under," he said.
Last year wasn't a good one
for the Consortium's hospitals.
"ln total, the six hospitals that
reported unaudited numbers
showed a substantial loss, $8
million, I think," Braun said.
"It's indicative of the environment and the problems we read
about in the papers every day. It
has nothing to do in a direct
sense with the Consortium, but
it influences people's ability to
participate and the needs that
they have."
Braun said it hasn't kept the
consortium from undertaking
any new programs so far, but,
"It's a consideration every time
we sit around the table and talk
about what new and innovative
programs can be tried."
Crossland said the hospitals
are hampered by low reimbursement rates for graduate education. "Some of the reimbursement is going to have to be improved," he said.
aughton agrees that the financial situation is serious. But
he remains optimistic about the Consortium .
"I think the threat is less if we continue
to share resources as we do," he said. "l
think the Consortium is a pretty good
response to the economic climate."
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"There is no dominant hospital. That's probably the biggest difference between
Buffalo and other consortia."

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Luther Musselman, M.D., director of medical

education for Millard Fillmore Hospitals

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�-PAYING OFF FOR
THE FUTURE, TOO

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ears ago, hospitals in Buffalo and

less serious now," said Andrew J. Rudnick, president

''There's always been a little bit of disquiet

elsewhere tended to look on other

of the local business group called the Greater Buffalo
Partnership.

about it," he added.
Now work is underway to form a new organi-

health care institutions as rivals.

They were motivated more by their own selfinterest than by what was best for the region.
While the Graduate Medical Dental Education

The business community pushed for creation of zation to replace the WNYHSC with a consortium
the WNYHSC because it was concerned that local

more directly under the control of the university

hospitals were duplicating services and spreading

and local medical community. The new consortium

Consortium of Buffalo didn't set out to solve that

some specialties too thinly over multiple institutions.

would include the GMDECB, which would continue
problem directly, it did help set the stage for anew As a result, there were inefficiencies and some pa- to operate without significant changes.
After several years of the WNYHSC, Rudnick
way of thinking and a new era of cooperation.
tients were traveling to other cities for treatment they
said, cooperative efforts have become institution"It helped to provide the mechanism for an should have been able to get in Buffalo.
Through the WNYHSC, UB and the area hospitals alized and business leaders no longer feel a need
evaluation," said medical school Dean John
Naughton, M.D.

now engage in more joint planning. Among other to be involved in the process. "We're not academic

"Getting the parties to the table served as a things, Naughton and others credit the Consortium medical people," he said. ''We're not clinicians.
springboard toward dealing with alarger agenda," with bringing a Trauma-Burn Center to Erie County We're not researchers. Ultimately it's got to be
agreed Michael F. Noe, M.D., executive vice president and medical director at The Buffalo General
Hospital. "Out of that, in 1987, the Western New

Medical Center, a Heart-lung Transplant Center to

turned over to them."
In addition to encouraging cooperation, the
The Buffalo General Hospital and a Bone Marrow
Transplant Center to Roswell Park Cancer Institute. new consortium will also focus on issues such as

York Health Sciences Consortium was formed."

Forming the WNYHSC proved more difficult than

new information systems and closer collaboration

The Health Sciences Consortium took the

the GMDECB because medical people were uneasy

betweentheuniversityandcommunityphysicians,

GMDECB concept one step further, going beyond

with the central role played by the business commu- Noe said.

the focus on training to look at the broader issue

nity. "It was a little bit more controversial because it

of providing quality care at low cost.

was threatening to physicians and faculty as well," will be in place by the end of the year.

Traditional hospital rivalries "seem to be far

Naughton said.

Naughton said he hopes the new consortium
-A

NDREW

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DANZO

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Spring Clinical Day and Reunion
Weekend '93 successfully staged
his year's Spring Clinical Day and
Reunion Weekend, held on April
30 and May 1, marked a time to
reminisce, renew friendships and
review health care practices today.
lt was, as always, a rousing
+
success.

From left to right- First row: Ronald
E. Martin, Victor Guarneri, Richard].
Buckley, r. , Gertrude Swarthout

Second row: Walter R. Peterson,
Kenneth Bone, Alfred S. Evans,
Duncan K. Macleod, Eugene M. Farber,
athan P. egel

From left to right- First row:
Thomas Grayson, Morris Unher,
Anthony Marano
Second row: Thomas Heineman, B.
joseph Galdys, Marvin Bloom, Harold
Feldman, jane Freiberg, George Heus,
William Keenan, Paul Wolfgruber, Ivan
Bunnell, Ralph Behling, Edward Crohn,
Richard jones
Third row: Louis Ciola, Edward Tracy,
Charles Tanner,john Ninfo

From left to right- First row: Harold
Graff, Daniel Fahey, Vernon Lubs
Second row: Edward Heckman, Raphael
Good, Myron Gordon , Daniel Miller,
Robert Hall
CLASS OF

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�CLASS OF 1 953

From left to right- First row:
David Batt, jacob Shammash, Richard
agel, joseph Ruh, Marvin Wadler,
Donald Ehrenreich, Thomas Geoghegan
Second row: Herbert Constantine, john
Strachan, Reinhold Ullrich, james
Coleman, Molly Seidenberg Panner,
Thomas Comerford, Howard Smith,
john Volunan, Milford Maloney, james
Orr, Ronald Garvey
Third row: Harley Lindquist, Curtis
johnson, Stanley Cohen, Donald
Rachow, john Handel, Bertram Portin,
Raymond Smith, Michael Sullivan,
Sander Fogel, Herbert Simpkins,john
Fenger

CLASS OF 1 958

From left to right- First row:
Melvin Brothman, Richard Rahner,
Thomas Cummiskey, Richard Wasson
Second row: Richard Romanowski ,
John Armenia, Marie Leyden Kunz ,
Lucien Potenza, Michael Mazza,joseph
Bellanti, jason Reder
Third row: William Glazier,john Float,
Michael Genco, Carl Contino, Donald
Ginsberg, jacques Lipson , Domonic
Falsetti, Robert Dickson, Bernice
Comfort, Ronald Batt, Franklin
Zeplowitz, Franklyn Campagna,
Joseph Zizzi, Samuel Shatkin, Alfred
Stein, Eugene Friedberg, Leo Kane,
Richard Boyle, Robert Perez, Gerard
Guerinot
Fourth row:David Koretz, Morton
Spivack, William Deverell, Gary Cohen,
Gaspare Alfano , Reinhardt Wende,John
Giardino, Elroy Anderson

CLASS OF 1963

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�CLASS OF 1 968

i

From left to right- First row:
john hields, Gary Karch, jeffrey Stoff
Second row: Bruce Gesson, Katherine
Dowling Schlaerth, Barbara Blase Sayres,
Sara Gerstman Sirkin, Thomas Cumbo,
Ronald Friedman, Morris Stambler,
Leonard Argentine
Third row: Lawrence Baker, Gerald
Daigler, Robert Baltimore, Albert Biglan,
Robert White, Lesbia Fernandez Smith,
Robert Rodner, john chlaerth, Geoffrey
Clark, Elias Rosenblatt, Harold Kulman
Fourth row: Bruce Rabin, jonathan
Reynhout, Brianjoseph, Lawrence
Dobmeier, julian Karelitz,john Bivona,
Robert Rosen,julian Offsay, Robert
Milch, Paul Murphy, Robert Dickman,
William Clack

From left to right- First row: David
Breen, Frederic Buchwald, Robert
Lamantia, Lynda Young, Sharon
Kuritsky, Paul Kuritsky, Thomas
Wasser, William Ackerman
Second row: Frederick Beck, Michael
Haberman, john Klimas, Michael
Sansone, Charles McAllister, Arthur
Mruczek
Third row: jacob Rozbruch, john
Przylucki, Dana Launer, Daniel
McMahon, Andre Raszynski, Charles
Wiles, Raymond Dattwyler, Arnold
Scherz, Demetrius Ellis, Thomas Dwyer
CLASS OF 1973

From left to right- First row: Michael
Blume, Ronald Somogyi, Elizabeth
Doherty,judith Baron-Stone, Richard
Elman
Second row: Stuart Dorfman, Kenneth
Glick, Matthew O'Brien, Stephen
Gawronski
Third row: teven Kaplan, Paul
Wopperer, Stewart Altmayer

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�CLASS OF 1 983

From left to right - First row: Robert
Smolinski, eal Smith, Richard Collins
Second row: Melinda Cameron, Mary
Lee, Suzzanne Tanbakuchi, Deborah
Korwin, Younghee Limb, Gwen
ichols, Andrea Manyon-Wild, Patricia
Flanagan
Third row: Ephraim Back, Kenneth
Zimmerman, James Koness, Daniel
Murak, Robert Rosen,jonathan Graff,
Gregory Zuccaro, Borys Loza, Michael
Chaskes, Kenneth Roth, Victor
Chehebar, Therese Giglia , Peter Accetta
Fourth row: Ross Greenberg, Lonny
Behar, Robert Stall, Carl Grant, James
Corasanti, Galvin Anderson, William
Hanavan, Kevin Ferentz, Mark
Schwager
Fifth row: Charles iles, icholas
Aquino, Frank Mezzadri, Frederick
McAdam, James Wild, Mark Venditti,
Allen Rosen

SPRING CLINICAL DAY

From left to right - First row: Judith
Hays, Lisa Benson-Guterman, Stephanie
Christenson, Ellen Adler-Weinberg,
Janet Williams-Barbaccia, Norah
Lincoff, Ann Marie Levine, Margaret
Morey
Second row: Kathleen O'Leary, Robert
Mennella, Paul Shields, Helen HessCappuccino, Lori Guttuso-Luzi,John
Barbaccia, Constance Greene-Klocke,
Lisette D'Eon , Ralph Pothel, Thomas
Bellomo
Third row: Charles Everett, Lisa
Guttuso-Klenk, Stephen Hughes,
Andrew Cappuccino, Wayne Waz ,
Frank Luzi, Dawn Hrab, Mark Klocke

Winners of the class with the highest percentage
of attendees pose for a picture.

The AMA's Dr. James Todd
lectures on health care reform.

Orvan Hess '31, wins an Alumni Achievement
award.

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lEI

Kathleen A. Lillis, M.D.

Lillis '87,appointed attending
physician in emergency medicine
athleen A. Lillis, M.D. , '87, was
recently appointed attending physician to the division of emergency
medicine at The Children's Hospital of Buffalo.
Her responsibilities include supervising resident and medical student
teaching in addition to overseeing all incoming patients.
Lillis is also medical director of the
stabilization and transport team, as well as
a child abuse and toxicology consultant
for the hospital and medical director of
Mercy Flight.
+

Frawley establishes endowment
for residency research fellowship
homas F. Frawley, M.D., '44, chairman of Graduate Medical Education at St. John's Medical Center
and Emeritus Professor of Medicine at St. Louis University School
ofMedicine, has established a charitable remainder unitrust through a gift of
securities valued at $50,000 to the University at Buffalo.
The unitrust will establish the Thomas
F. Frawley, M.D. Residency Research Fellowship in the School of Medicine and
Biomedical Sciences. The endowment will

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provide a stipend for a resident to perform
r search for one year before deciding to
follow primarily a medical re earch career
or elect to go into clinical practice.
Frawley received the Distinguished
Medical Alumnus Award in 1989 and
served as chairman of the medical school's
annual fund drive in 1992.
He served as president of the American
College of Physicians from 1981 to 1982
and recently was the 1993 recipient of the
Alfred Stengel Memorial Award presented
to a Master of the College who has exhibited "unusual loyalty and exceptional contributions to the aims and purposes of the
College as well as outstanding influence in
maintaining and advancing the best standards of medical education, medical practice and clinical research."
+

Two annual awards endowed for
graduating medical students
enjamin E. Obletz, M.D. , '32, retired
Buffalo surgeon, and his wife, Lila,
have established the Dr. Benjamin
and Lila Obletz Fund to support a
prize in orthopaedic surgery to be
awarded annually to a graduating
senior.
Obletz received both his undergraduate and medical degrees from the University at Buffalo and has served as a clinical
professor of orthopaedic surgery from
1956 until the present.
Mrs. june Alker has endowed a fund in
memory of her husband, George]. Alker,
M.D., '56, chairman of the department of
radiology at UB from 1985 to 1991. The
fund will provide an annual award at
commencement to an outstanding student in the area of neuroradiology.
Dr. Alker, who died December 31, 1991,
was born in Budapest, Hungary, and immigrated to the United States in 1949 as a
refugee. He was director of radiology at

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Erie County Medical Center and a member of the American Society of
euroradiology.
+

Lillian Ney'64,named diplomate
of medical management board
illian Vitanza ey, M.D., '64, vice
president for medical affairs and
medical director ofW.C.A. Hospital
in jamestown, ew York, has been
designated a diplomate of the American Board of Medical Management,
the national certifying agency for physician executives.
ey, who has been with W.C.A. Hospital for 19 years, is board certified in internal medicine and cardiovascular disease.
She is a fellow with the American College
of Physicians, the American College of
Cardiology and the Council of Clinical
Cardiology of the American Heart Association. She is also a member of the American College of Physician Executives. +

Reisman '56,named master in
American College of Physicians
obert Reisman, M.D. , '56, has
been named a master in the
AmericanCollege of
Physicians.
Reisman,
UB clinical
professor of
pediatrics, is
currently
President of
the Medical
Alumni Association.
+

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Innovative palliative care training
program begins at Hospice Buffalo
or the first time, fellows from the
Graduate Medical Dental Education
Consortium of Buffalo are receiving
training in palliative care at Hospice
Buffalo.
The eight-week rotation, under
the auspices ofUB and the ational Institutes of Health Summer Program, emphasizes attitude, knowledge and skill.
Under the leadership of Robert Milch,
M.D ., medical director of Hospice Buffalo,
the fellows examine the interdisciplinary
approach of palliative care and how the
therapeutic process involves more than
diagnosing and attempting to revert advanced disease. Emphasis is placed on
interventions as they relate to the patient's
needs , desires and beliefs, and assuring
patients have as much control as possible
over decisions that affect them. The fellows are also involved in discussions on
the ethical aspects of caregiving, including
euthanasia , resuscitation , paternalism,
aggressive versus palliative interventional
therapy, incompetent patients, fairness in
the health care system and strategies for
resolving ethical issues.
The curriculum covers common symptoms in patients with advanced chronic
disease along with suggestions of appropriate techniques to combat them. Elements of grief reactions and preventive
techniques for adverse reactions are also
addressed. The rotation identifies various
organizational arrangements for the delivery of palliative care and their relationship
to the health care system, including community resources available to patients with
advanced illnesses and their families .
The fellows rotate through each clinical discipline of hospice care, examine
methods used in nursing homes and accompany counselors on social work and
bereavement visits.
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The training follows an interdisciplinary approa(h to palliative (Ore that re(o.gnizes the therapeuti(
pro(ess involves more than diagnosing and attempting to revert advan(ed d1sease.

Pediatrtc fellow receives research
award from national association
elawati Yuwono , M.D., a fellow in
the division of pediatric gastroenterology/nutrition at The
Children's Hospital of Buffalo has
received a Glaxo Fellow award for
her abstract, the "Role of Promoter and Suppressor Genes During
Adnomidis Polyp Development in Familial Polyposis Coli."
Yuwono presented her data at the annual
meeting of the American Gastroenterological
+
Association.

"Membership in the consortium
strenothens
and improves the quality of
b
Memorial's family practice residency program through increased coordination with
the State University of ew York at
Buffalo's medical and dental schools and
other area teaching hospitals," Memorial
president Timothy]. Finan said.
"Our participation will cement an effective working relationship and improve
communication to the benefit of our resident physicians, the hospital and the community. "
+

Niagara Falls Memortal Medical
Center joins Buffalo Consortium
iagara Falls Memorial Medical Center has joined the Graduate Medical
Dental Education Consortium of
Buffalo to strengthen and enhance
its family practice residency program.

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Resident training at Niagara Falls Memorial
Medi(al Center will be enhan(ed.

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"In Sickness and in Health" chronicles
the plight of Alzheimer's disease victims
he Western ew York Chapter of
Alzheimer's Disease and Related
Disorders Association has found
an unusual way to raise money for
its support services and promote
awareness of the disease.
lt has hired Buffalo Ensemble Theatre,
a downtown professional company, to
produce In Sickness and in Health, a new
play about a family struggling to cope with
the advancement of the disease.
The play, by Donna Marie Vaughan,
will be presented ovember 4, 5, 6 and 7
at Lancaster Opera House. All proceeds
will benefit the local chapter.
In Sickness and In Health, which is expected to receive national coverage, opens
with Cecilia, a mother of four now in her
late 50s, rummaging for her mislaid checkbook, which her husband, Emmet, eventually finds in the icebox. As the play
progresses, Cecilia's condition steadily
deteriorates, and Emmet alternates between shielding the severity of the disease
from the children and visitors and grappling with the temptation to give his wife
up to professional care.
"Losing a person so gradually is more
painful than death," said Marion Goldstein,
M.D. , UB principal investigator of psychiatry who sits on the Alzheimer's Disease Association's Board ofDirectors. ''I've
known a lot of people [who have] run
away from it. But living to the fullest with
a partial mind is something we should all
know and share in - it enriches us."
In Siclmess and In Health throws an
unusual and sensitive spotlight on the
other victims of the disease that afflicts
four million Americans: their families. lt is
the hope of the Alzheimer's Disease

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Association's Western ew York chapter
that the play will heighten awareness of
both the severity of the disease and of the
day-to-day struggles of the husbands,
wives, children and friends- "caregivers"
-who also live with it.
"Donna came to us with the script in
1991 and consulted with our education
director," said Sharon Ross, the chapter's
executive director. "We've been looking
for ways to produce it ever since.
"What we're excited about is the opportunity for an innovative way of entertaining and educating people about
Alzheimer's through the medium of theatre. "
Ross said that she would be bringing
the actors into contact with Alzheimer's
sufferers so that
they could stud)
the symptoms o
the disease.
The local Alzheimer's Disease
Association is one
of 215 chapters
working to alleviate the burden
of the disease on
victims and their
families.
Western New
York's Chapter is
armed by 100
volunteers who
serve Allegany,
Chautauqua,
Erie, Genesee,
iagara, Orleans and Wyoming counties.

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The support groups reflect a national
web of interest and research that provides
assistance for both those suffering from
the disease and the next of kin who must
continue to provide care as the disease
takes its confusing and frequently devastating toll on daily life. The Western ew
York Chapter's newsletter, for example,
carries the advice, "You never win an
argument with an Alzheimer's patient,"
from the Association's San Francisco chapter; the Greater Washington chapter offers
tips "On Hiding Things."
The association has also developed a
program called "Safe Return," which helps
locate patients who have wandered off
alone (59 percent of sufferers are afflicted
with what can be life-threatening wandering, and 70 percent of patients surveyed
indicated wandering was a frightening
factor in their lives.) The program, the
impetus for which was the death of a
wandering Buffalo patient in October of
last year, enrolls patients in a national
database and issues identity tags and brace-

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l§JJ
lets for a small fee. It also trains those who
may not have had contact with the disease
- and especially police and emergency
crew members - in recognizing and responding to its symptoms.
Information on Alzheimer's Association Western ew York support groups
and its "Safe Return" program may be
obtained by calling (716) 873-1335 or 1800-273-6737; information on purchasing tickets for In Siclmess and In Health
may be obtained by calling (716) 8731335 or (716) 855-2225 .
+
-

B Y

R O B ERT

W AT ERH OU SE

PranikoiT elected asecretary of
Amertcan Urological Association

"Then and Now"will chronicle 150 years of
medical school history

evin Pranikoff, M.D., associate professor and vice chair of urology,
has been elected secretary of the
Northeastern Section of the American Urological Association for a
five-year term.
As secretary to the association, Pranikoff
will coordinate its affairs as well as sit on
its executive committee. He is the first
urologist from the Buffalo area to be elected
to the position.
+

n 1996, the University at Buffalo- and its founding School of Medicine
and Biomedical Sciences- will celebrate 150 years of service.
Beginning with its next issue, Buffalo Physician will commemorate the
Sesquicentennial with the inauguration of o special series called "Then and
Now," which will look at various aspects of what the medical school was like
over the post 150 years. The series will toke both o historical perspective and o personal one with articles about what life was like for early medical students, clinicol "firsts," personol "firsts"
and the history of the affiliated hospitals.
In addition, Buffalo Physicianwill excerpt articles from The Buffalo Medical Journal, first
published in 1845, and keep its readers abreast of the various events and exhibits scheduled to
celebrate the Sesquicentennial.

Stapleton appointed chair of
pediattic nephrology sub-board
Bruder Stapleton, M.D. , A. Conger
Goodyear professor and chair of the
Department of Pediatrics, has been
named chair of the sub-board of
pediatric nephrology of the Ameri1can Board of Pediatrics for 1993.
The six-member board is responsible
for certifying pediatric kidney specialists
in the United States.
Pediatrician-in-chief at The Children's

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Examiners, a member
of the American Pediatric Society and sits
on the executive councils of the Eastern Society for Pediatric Research and the American Society of Pediat+
ric Nephrology.

Hospital ofBuffalo, Stapleton recently was
named assistant secretary general of the
International Pediatric ephrology Association.
A fellow of the American Academy of
Pediatrics, he is certified by the American
Board of Pediatrics and its sub-board of
pediatric nephrology. He is also a diplomate of the American Board of Medical

y

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[1]
~

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Two UB professors elected to
Amertcan Pediatric Society
aniel Green, M.D., and Bradley
Fuhrman, M.D., UB professors of
pediatrics, have been elected to the
American Pediatric ociety for outstanding contributions to the field
of pediatrics.
Green, professor of pediatrics in the
division of hematology/oncology, is chief
of the oncology section in the department
of pediatrics at Roswell Park Cancer Institute.
He is also a member of the Scientific
Committee of the International Society of
Pediatric Oncology and the Society of
Pediatric Research.
Fuhrman heads the divisions of critical
care medicine at The Children's Hospital of
Buffalo and in the department of pediatrics at the medical school. He is a member
of theNorthwestPecliatricSociety, the American Academy ofPediatrics and the Society of
+
Critical Care Medicine.

Congratulations abounded as
the S(hool of Medidne and
Biomedkal Sden(es' Class of
199 3 attended its (Ommen(e·
ment (eremonies in May.

editorial board of thejoumal of Urology.
Mark Ballow, M.D., professor of pediatrics and chief of the division of allergy/
immunology at The Children's Hospital of
Buffalo, has been appointed to the editorial board of the ]oumal of Clinical Immunology.
Donald Opila, M.D. , clinical assistant
professor of medicine, received the "Young
Internist of the Year" award from the
American Society of Internal Medicine at
+
their recent national meeting.

chair of medicine and microbiology and
chief of the division of infectious diseases
at UB untillastjanuary.
The vaccine was judged the most promising invention among 40 entrants selected from more than 300 inventions
receiving patents in 1992 in Western ew
York. If it proves effective in humans, the
vaccine will be a major medical breakthrough in the treatment of ear infections.
The vaccine may also be effective against
+
lung infections in adults.
B

UB researcher Murphy named
Inventor of the Year for 1992
wo researchers who developed a
vaccine with the potential to provide immunity against middle ear
infections were selected iagara
Frontier Inventor of the Year for
1992 by the Technical ocieties
Council of the iagara Frontier and the
iagara Frontier Patent Law Association.
Timothy Murphy, M.D. , UB professor
of medicine and microbiology and director of its microbial pathogenesis graduate
group, and Michael Apicella, M.D., professor and chair of the department of
microbiology at the University of Iowa
College of Medicine, were honored for
their work. Apicella was professor and

Bradley Fuhrman, M.D.

UB physicians honored by award
and journal board appointments
hree UB physicians have been honored for their expertise in their repective fields.
Gerald Sufrin, M D., professor
and chairman of the department of
urology, has been appointed to the

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LOIS

B

AKER

Life Technologies donates labware
for use in cell culture research
abware valued
at $45,000 for
use in cell culture research
recently was
donated to the
medical school b y
GIBCO Life Technologies, Inc.
Life Technologies,
headquartered in Niagara Falls, ew York,
develops, manufactures and sells molecular biology products and cell culture products under the BRL and GIBCO brand
+
names.

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director of the Delhi and Stam-

structive pelvic surgery.

George A. Gentner '41, of Phoe-

'85, is presently a fellow in neonatology at the SU Y HSC.

ford offices of the Mary Imogene

nix, Arizona writes, "I have been
retired for several years now and
enjoy coastal cruising on a sailboat off southern California."

John E. Shields '68, is medical

particularly in the field of recon-

s

I

Raymond Moffitt '48, retired in

Bassett Hospital of Cooperstown,

1989 as chief emeritus of gastroenterologyatSt.Joseph's Hospital

New York.

Jeffrey G. Straus '84, writes, "I
am a contributing author to the
text Ophthalmic Anesthesia (Slack,

in Providence, Rhode Island. He

Sogba K. Bosu '69, is a pediatri-

Inc., 1993); thechapterisonStraus

William D. Loeser '45, of Young-

now enjoys golf and working part-

cian/neonatologist with the

Retrobulbar

stown, Ohio, closed his practice

time

elderly in

Southern California Permanente

nique, U.S. Patent#4,759,746."

arragansett, Rhode Island, and

Medical Group, Orange County,

in 1989; he is currently medical
director of a preferred provider

with

the

California, assistant chief of pediatrics and director ofNicu-Kaiser

Sarasota, Florida.

organization.

1

9

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Hospital, Anaheim, and chairman

s

Robert A. Benninger '50, of Cape

of the pediatrics department, West

Coral, Florida, informs us that he

Anaheim Medical Center.

Allyn, are expecting a second child
in September.
Paula Rothman '85, has joined a

1

9

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s

orthopaedic surgery and is cur-

Maxine Hayes '73, is assistant

rently helping to build a church.

secretary of health for Washington State. She is president elect for

tice in Birmingham, Alabama.
Michael]. Bartiss '87, has joined
the Carolina Eye Associates in

the Association of Maternal Child

Southern Pines/Pinehurst,

of radiology at the Medical Col-

Health Programs. Hayes received
her MPH from Harvard Univer-

Carolina, as a pediatric ophthal-

lege ofWisconsin, has been elected

sity School of Public Health in

to the board of trustees of the
American Board ofRadiology. His

1977.

James E. Youker '54, professor
and chairman of the department

six-yearterm beganJuly l. Youker
practices at the Milwaukee County

1

Medical Complex and Froedtert
Memorial Lutheran Hospital,
ichols '47, chief of

where he specializes in chest radi-

gynecologic pelvic surgery at Mas-

ology, cardiac radiology and

sachusetts General Hospital, was

mammography.

David H.

Kevin M. Miller '85, ofWoodland
Hills, California, and his wife,

reproductive endocrinology prac-

sold his airplane but still has a
sailing sloop. He retired from

David H. Ni(hols

eedle and Tech-

1

9

6

0

mologist.
MarkS. Courey '87, has joined
the faculty of Vanderbilt Univer-

9

8

0

s

sity,

ashville, Tennessee, after

completing a fellowship in voice

George C. Geraci '80, is now board

disorders and care of the profes-

certified in medical management,

sional voice.

emergency medicine and family

named Outstanding Surgeon of
the Year at the annual meeting of

orth

s

practice. Geraci is medical direc-

Robert H. Goldklang'87, received

tor of primary and urgent care for
Capital Health System in Harris-

a Clinical Research Award from

burg, Pennsylvania.

Health in 1992 and was selected

the Glaxo Institute of Digestive
to receive a renewal of the grant in

the Society of Gynecologic Sur-

Alan L. Pohl '62, informs us that

Andrew M. Knoll '84, having suc-

1993. Goldklang is a junior fac-

geons, held in PhoenLx.

his son, Andrew, graduated from

cessfully delayed his residency

ulty member in the department of
internal medicine at the Univer-

ichols,

formerly a professor and chair-

the University ofWisconsin Medi-

until the enactment of Section

man of obstetrics and gynecology

cal School and is a radiology resi-

405, is completing his final year of

sity of California at San Diego

at Brown University, is currently a

dent at Michael Reese Hospital in

training as chief resident in inter-

School of Medicine/San Diego VA

visiting professor at Harvard Medi-

Chicago.

nal medicine at the SUNY HSC in

Medical Center. Currently, he is a

cal School and Massachusetts

Syracuse. He has accepted a posi-

General Hospital. He is known for

William M. Burleigh '67, of

tion as attending physician in the

his innovative surgical contribu-

Rancho Mirage, California, in-

Emergency Department at St.

tions to the health care of women,

forms us his daughter, Jennifer,

Joseph's Medical Center in Syra-

was born March 11, 1992.

cuse. His wife, Maritza Alvarado

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trainee member of the American
Gastroenterological Association
and a member of the American
College of Physicians.

�•

····························· ······ ········ ··· · ········ ·· ·································
.

'

Deborah Shalder '87, writes, "I
won a fir t place in watercolor at
the annual exhibit of the American Physician AnA ociation held
in San Antonio, ovember 1992."

joseph Aferzon '89, announces
the birth ofRacheljessicaAferzon
onjanuary 11 , 1993. Aferzon is a
third year neurosurgery resident
at Hartford Hospital, University

Stephanie is now Child Care Director at the YMCA."

Scott Svitek '90, is chief resident
in pediatrics at Long Island jew-

of Connecticut.

Ronald A. Alberico '90, was
picked as one of the 40 best sec-

ish Hospital.

Debra M. Omiatek '89, is currently employed as clinical director at the Tuscarora Indian Health
Center.

ond-year radiology residents in
the country. He has two children:
Zachary Ryan, two, and Karissa
icole, 11 months.

Matthew]. Phillips '91, and his
wife, Toula, announce the birth of

Stuart Varon '89, has been appointed chief resident of child and

Ronald Palazzo and Ellis Gomez
Palazzo '90, announce "our new

Richard G. Bennett '92, is cur-

adolescent psychiatry at the West-

addition, Ana-Maria Elaina, was

psychiatry at Case Western Re-

born September 17, 1992. Both of

serve University Hospitals in
Cleveland, Ohio.

David]. Pochatko '88, completed
an orthopaedic surgery re idency
injune and began a foot and ankle
fellowship at Emory Univer ity.
Pochatko plans on practicing in

us completed family practice residencies in june."

very helpful bigsisterjanee.Janee
was three years old in February.

theirson,JamesMatthew,onApril
7, 1993.

Buffalo.
Helen Cappuccino '88, a general
surgeon, and Andrew Cappuccino '88, an orthopaedic surgeon,
proudly announce the birth of
their fourth child, Nicholas An-

em Psychiatric Institute and Clinic
of the University of Pittsburgh,
Pennsylvania, for 1993-1994.

rently in the residency program in

thony.

1

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Ranjan Bhayana '90, announces
the birth of his second daughter,
Brittney Paulina, on March 4,
1993. Bhayana has relocated to
the Buffalo area.
Daniel F. Klee '90, began a cardiology residency at Good Samaritan Hospital in Phoenix in july.
Pierre]. Moeser '90, of Chesterfield, Missouri, writes, "I will be in
the citizen ambassador program
rheumatology delegation to Russia and the Czech Republic in
October 1993."

Anna Kristina E. Hart

Anna Kri tina E. Hart '89, writes,
"I am still on active duty in the
navy as a flight surgeon, currently
in Pensacola, Florida. In earlyJune
I'll be transferred to Whidbey Is-

land, Washington , for one additional year before resuming re idency."

B

a

William F. Balistreri '70, has been
named the recipient of the Distinguished
Medical Alumnus Award for 1993.

5

Ronald Alberico '90, is chief resident in radiology at Long Island

0

BIT

U

ARIES

Evelyn Heath Jacobsen '24, died April 12, 1993, after a long
illness. She worked for almost 50 years at The Children's
Hospital of Buffalo, both full-time and part-time, until her
retirement at age 70. The jacobsen Ambulatory Care Center at
Children's Hospital was named for her and her husband, the late
A. Wilmotjacobsen, M.D.
Arthur C. Hassenfratz '28, died December 13, 1992. Hassenfratz
was in private practice in Buffalo for 52 years.
Rutherford S. Gilfallan '41, died in Dillon Beach, California,
ovember 27, 1992, after a long illness.

jewish Hospital.

john F. Perry'S!, died December 25,1992, in Gilroy, California.

William Palmer, Jr., '90, writes,

James M. Garvey '55, died of emphysema at his home in Olean,

"My wife, Stephanie, and I an-

New York, March 8, 1993.

nounce the birth of our second
daughter, jilian, on October 11,
1992. She joins her proud and

a

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james]. Freeman '74, of Medford, New York, died of a heart
attack April 18, 1993. Dr. Freeman worked for the assau
County Health Department.

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Spoonful

of

Humor

©

Stu

Silverstein ,

M.D .

Future Perfect?
THE TIMES THEY ARE A 'CHANGIN FOR HEALTH CARE

eligious friends of mine tell me that we are living in the
Messianic Era. With the scores of changes occurring
recently, I remain open to this possibility, for these are
indeed strange times. It's either that, or virtual reality
scientists are playing a clever trick on all of us.
Recently, we have seen the almost unthinkable - the
death of Superman, and over the summer Charlie Brown
finally hit that elusive home run after years ~f striking out. A
colleague of mine just informed me that john Bradshawemperor of the dysfunctional family, admiral of the good ship
healthy functioning- is getting a divorce (which sort of begs
the question, "who gets custody of his inner child?").
The changes are particularly frightening for those of us in
health care. And if all these changes aren't enough, we are
facing the specter of two lawyers determining the
economics of health care for the coming century
-one lawyer who spent $200 at~~=-~~Z
airport for a haircut and one, it
seems, who spent 2 at the
supercut drive-thru window. I am
waiting for Hillary to actually bill us for
35,064 hours of service in 1996. Indeed, I
am hoping that she doesn't expand the
concept to "drive-thru" short-stay surgery
to cut down on health care costs.
When I decided to become a pediatrician, I did so despite warnings that I
Would end up standing at the entrance to U.S. l 0 l holding a "Will do
LPs for food" sign to make ends meet
and pay off my student loans.
At times I've thought about it, but
resisted the temptation (primarily because
there is barely room with all those unem~loyed lawyers holding up signs expresstug their willingness to litigate for the same).
ow it seems that those who decried my
going into primary care - my colleagues who
chose careers in radiology and dermatology Will soon find that the real prestige will rest with those of us
who chose primary care. According to Hillary Rodham Clinton,
we're going to be the darlings of the new health care plan
they're generating.
At last I'll never again be asked to sit at the kiddie table
during staff meetings, or play miniature golf to match my

miniature salary.
The possibilities are excitmg. We could soon see
orthopaedists ordering "total" malleus, incus and stapes replacements to treat chronic otitis media, or perhaps general
surgeons performing below-the-cochlea amputations for the
same ... call it the van Gogh procedure- CPT code number
9990.
Pathologists will prove what most of us suspected all along
-that they know it all and this time they won't arrive when
it is too late. Yet, this is perhaps what is awaiting us under the
"managed competition" now being proposed by the Clinton

administratio::,n~.-~~""

Managed competition is
one of those oxymorons we've seen
over the years, like "military intelligence," "government help" and "Super
Bowl champion Buffalo Bills."
What is managed competition anyway? I envision patients comparison-shopping from city to city,
and hospitals setting up cubicles like those seen at
car dealers. "OK Mr. Goodname. We'll throw in the
epidural and the appendectomy, but the vasectomy
will take me below cost - might have to call in a
urologist, or even a plumber if you're willing to pay
the difference. Let me check with my manager
first!"
President Clinton has promised us universal health coverage with acceptable quality,
but he didn't mention that he will be using
virtual reality technology to do it. This may
not be such a bad idea, and actually may be
the way to obtain not only universal health
care coverage, but universal satisfac' tion in life-disgruntled postal workers could express their dissatisfaction
while firingvirtualreality guns, Ross Perot
could fulfill his megalomaniacal fantasies
and actually become CEO of the country if not
the universe in the privacy of his own home
while leaving the rest of us alone. And maybe through the
wonders of virtual reality technology, we can even see the
unthinkable- the Bills winning a Super Bowl.
Well, some things even in these times remain virtually
+
unrealistic.
Stu Silve~tem, M.D., president of Stoooup Medicine Semino~ of Son fmocill:o, Colifom~. lectures nationwide on humor rn medi&lt;ine.

�BUFFALO PHYSICIAN
STATE UNIVERSITY OF NEW YORK AT BUFFALO

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I

I

State' Unive!sity, of New York at . Buffal~ School of Medicine and Biomedi~al Sciences, Spri.ng 199.4

�BUFFALO PHYSICIAN

Volume 28, Number 2
ASSOC IATE VICE
PRES I DENT FOR
UN IVERS ITY
ADVANCEMENT

Dr. Carole Smith Petro
DIRECTOR OF
PUBLICATIONS

Timothy j Conroy
EDITOR

Nanette Tramont Kollig, R.N.
ART DIRECTOR

Alan j Kegler
ASSOCIATE ART DIRECTOR

Scott Fricker
PRODUCTION MANAGER

Ann Raszmann Brown
STATE UNIVERSITY OF
NEW YORK AT BUFFALO
SCHOOL OF MEDIC I NE
AND B IOMED ICAL
SCIENCES

Dr john Kaughton , Vice President
for Clinical Affairs, Dean
EDITORIAL BOARD

Dr. john A. Rtchert, Chairman
Dr. Martm Brecher
Dr. Harold Brody
Dr. Richard L. Collins
Dr. Alan j. Dnnnan
Dr. Timothy Gabryel
Dr. james Kanski
Dr. Charles Massaro
Dr. Charles Paganelli
Dr. Robert E. Reisman
Dr. Thomas Rosenthal
Dr. Stephen Spaulding
Dr. Bradley T Truax

Dear Friends,

C

hanges in medical education and health care are occurring at breakneck speed! UB's
medical school and its affiliated teaching hospitals fortunately began developing a
strategy for coping with the anticipated adaptations in the mid-l980s. Some of the
required efforts were made possible through the development of a demonstration
project that served to modify the priorities and directions of the graduate medical
education programs. This has been largely accomplished through the Graduate Medical
Dental Education Consortium of Buffalo. In the late 1980s, the school's faculty agreed to
pilot a comprehensive two-month ambulatory clerkship in the fourth year.
During the past two years, the Curriculum Committee has begun
its re-evaluation of course offerings to ensure that future graduates
will be properly prepared for national health care reform. This effort
has been enhanced by the planning grant received from the Robert
Wood Johnson Foundation and the school has submitted its final
proposal to the foundation in the hope that UB will be among the l2
finalists to receive its support over the course of the next five years.
These funds will be directed to assist the faculty in making the
required changes in curriculum offerings and to assist in the adaptations in educational technique and support that must be forthcoming. Already, some significant changes are occurring. For example, beginning this fall, a
formal clerkship will be offered in family medicine; the departments of medicine and
surgery will modify their clerkships so that each department will offer new one-month
courses in the fourth year. The Curriculum Committee, faculty and students have initiated
their evaluation of years one and two, and obviously new innovations and designs should
be forthcoming for these academic calendars in the years ahead. We hope to be able to
position the school and its affiliates so they can respond positively to the changes that lie
ahead and to maintain our commitment to excellence in teaching, research and patient
care.
Sincerely,

John aughton , M. D.
Vice President for Clinical Affairs
Dean, School of Medicine and Biomedical Sciences

TEACHING HOSPITALS AND
LIAISONS

Batavia VA Medical Center
Arlene Kelly
The Buffalo General Hospital
Michael Shaw
Buffalo VA Medical Center
The Children's Hospital of Buffalo
Erie County Medical Center
Mercy Hospital
Millard Fillmore Health System
Frank Sava
Roswell Park Cancer Institute
Sisters of Charity Hospital
Dennis McCarthy
«:&gt;The State University of New York
at Buffalo

Buffalo Physician is published
quarterly by the State University of
New York at Buffalo School of
Medicine and Biomedical Sciences
and the Office of Publications . It is
sent, free of charge, to alumni ,
faculty , students, residents and
friends. The staff reserves the right
to edit all copy and submissions
accepted for publication.
Address questions, comments and
submissions to: Editor, Buffalo
Physician, State University of New
York at Buffalo, University
Publications, 136 Crofts Hall,
Buffalo , New York 14260

Dear Fellow Alumni,

T

he 57th Annual Spring Clinical Day, the traditional highlight of the Medical Alumni
Association's activities, will take place on April30 at the Buffalo Marriott Hotel. The
general reception for all Reunion Classes will be held on Friday evening, April 29,
at the Center for Tomorrow. The five-year class reunion chairs have planned their
Saturday evening receptions, a unique and ever more meaningful time to renew
"old" close acquaintances and rehash unforgettable memories.
This year, we have a most exciting and innovative program, addressing current and
future issues in medical education- a subject that should be interesting and appealing
to all attendees. The complete program can be found on the Alumni
Section pages of this issue. The morning presentations set the basis
for the Stockton Kimball Lecture, which will be presented by Jerome
P. Kassirer, M.D., '57 , editor of The New England journal of Medicine,
and a premier medical teacher and educator. His topic will be
"Clinical Reasoning: Teaching it and Learning it. " As a personal note,
I thank Dr. Kassirer for accepting this invitation. He is a past recipient
of our Distinguished Alumnus Award and holds one of the most
prestigious positions in American medicine.
Thi• •hou\d b• '" ou~&lt;anding w"~

Send address thanges to:

Buffalo
Physician, 147 CFS Addition , 3435
Main Street, Buffalo, New York
14214

Robert E. Reisman, M.D., '56

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Five of the six new
Consortium hospital CEOs. From left,
Robert V. Stanek, Charles Van Vorst,
Lynn Brown, Joseph Ruffolo
and Paul Candino.

Research
Hospital News
Leading Buffalo's Changing Health Care Scene e Six
Dr. Roswell Park performs surgery. From
The Pictorial History of the Medical School
collection. Page 25.

of the nine affiliated teaching hospitals have
new CEOs. What will the changes mean?

Changing the Face of Medical Education e The School
of Medicine and Biomedical Sciences is moving
steadily toward a new way of teaching that stresses
analysis over memorization and patient interaction over crowded lectures.

Medical School
Alumni
ASpoonful of Humor
Graduate Education
Classnotes
Going home. Page 34.

Alum Jack Coyne blends
two callings. Page 30.

�.... . .. . . .. . .. . .. . .. .. .. . . . ... . . ... . .. . ..... . . .. ... ... . .. ... . .. .. . . ...... ... .. . . ... .. . .. . .

.'
.

UB research continues on NASA's
Spacelab Life Sciences 2mission
B research done on the first
Spacelab Life Sciences mission that
showed the body regulates the
cardiovascular system in a novel
way, continued on last October's
Spacelab life Sciences 2 mission
with three more astronauts over a longer
period of time. The research was designed by a team of scientists headed by
leon E. Farhi, M.D., distinguished professor of physiology.
Results from the first mission showed
that during space flight the cardiovascular system adjusts vascular tone to
maintain blood pressure in the face of
elevated cardiac output.
"This type of regulation ofblood pressure was completely unexpected, " Far hi
says. "The system's failure to reduce
cardiac output surprised us."
Earthbound research in simulated
weightlessness has shown that when
gravity is eliminated, the heart pumps
more blood initially, but the body eventually reduces total blood volume by
eliminating blood plasma through urine
to maintain normal blood pressure.
Astronauts on the Spacelab missions
used special equipment designed by UB
technicians to determine how the heart
and lungs perform in and adapt to the
weightless environment of space during exercise and at rest and how that
adaptation affects the astronauts' readjustment to gravity. Results from the
initial study found that astronauts did
not regain normal cardiovascular balance and could not perform the
experiment's exercises fully for at least
seven days.
UB researchers speculate that even
five more days of weightlessness in space
could cause more pronounced and
longer-lasting effects on the heart and

lungs. The experiment was one of three
studies conducted during the mission
that focused on the astronauts' cardiovascular functioning in zero gravity.
Astronauts David Wolf, M.D. , Shannon lucid, Ph.D., and Martin Fettman,
Ph.D. , trained for more thana year a tUB
and the johnson Space Center in Houston to learn how to conduct the
experimets in the confines of the Space
Shuttle Columbia.
-

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Highest sepsis mortality rates
found from respiratory infections
lderly patients who develop sepsis
from respiratory infections while
hospitalized have higher mortality rates than patients who develop sepsis from all other infection groups , according to a study
by UB's Center for Pharmacoepidemiology Research.
Sepsis is the most common cause of
death in intensive care units, according
to Thaddeus H. Grasela , Pharm. D., assistant professor of pharmacy and director of the Center. Grasela was the principal investigator on the I, 758-patient
study that revealed mortality rates that
varied widely depending on the source
of the sepsis infection.
Patients with sepsis acquired from

respiratory tract infections had the highest mortality rate at 59.3 percent. The
lowest mortality rate was reported in
patients who developed sepsis from a
community-acquired urinary tract infection.
Mortality rates for patients who acquired sepsis from other infections were:
• 46.4 percent for hospital-acquired
urinary tract infections.
• 45 .8 percent for patients with abdominal infections.
• 36.7 percent for patients with skin
infections.
• 35 .9 percent for gram-negative
bacteremia inclusive of all sources.
• 28.3 percent for respiratory tract infections acquired in a nursing home.
• 24.6 percent for urinary tract infections acquired in a nursing home .
The multi-center study followed patients receiving antibiotics for suspected
or documented cases of gram negative
infections that can lead to sepsis from
the beginning of their treatment until
their discharge from the hospital or
death.
+
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Liposomes curb taxol's toxicity
sing liposomes to deliver taxol has
allowed researchers to control resistant tumor growth in animals
with doses of the drug that would
be lethal if delivered traditionally.
UB and Roswell Park Cancer
Institute scientists reported in the December 15, I993 issue of Cancer Research that the liposome delivery system may overcome some of the major
obstacles to the more effective use of
taxol in fighting cancer.
"Taxol has two problems," said Robert Straubinger, Ph.D., assistant professor of pharmaceutics and lead author of
the study, "The drug itself is toxic and

�·············· · ············································· · · · ······················ · ····~

the solvent in which it is administered is
also toxic."
Straubinger's experiments showed that
the use of liposomes to deliver taxol allowed it to be administered rapidly and in
doses between two and seven times larger
than those the animals would have been
able to tolerate as free drug.
"We're quite encouraged, " said
Straubinger. "By encapsulating taxol in
liposomes, we have caused a marked
decrease in toxicity and increased the
drug's potency.
"Right now," he added, "patients who
take taxol have to be treated heavily
with antihistamines and steroids. That
controls the side effects, but some of
these supplementary drugs may interfere with the same systems that transport or metabolize taxol within the
body."
Liposomes, he explained, although
they are essentially fat-soluble, are also
very stable in water and thus provide a
way to dissolve fat-soluble drugs such
as taxol in the body.
"Liposomes are particles with an oily
core, and a fat-soluble drug like taxol
tends to stay with them," Straubinger
said. "As a result, we have reduced the
massive wave of free drug that causes
some of the side effects."
The UB researchers compared the
conventional delivery of taxol against
taxol in liposomes in animals with colon cancer, even though the drug has
not shown to be effective in controlling
colon cancer growth.
"We were able to see control of tumor
growth in animals given multiple injections of liposomes containing 40 milligrams of taxol per kilogram of body
weight," Straubinger said. "If you gave
that amount as free drug, it would have
killed the animals. But in liposomes, it
didn't. It just controlled the tumors
nicely."
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UB'sDrug Surveillance Network
tracks drug reactions nationwide
he University at Buffalo's Drug
Surveillance Network (DS ) is the
only network of hospital pharmacists in the U.S. designed to rapidly track and share information
about how patients react to drugs.
Established by UB's Center for
Pharmacoepidemiology Research with
grants from pharmaceutical companies,
and supported with a grant from the
Food and Drug Administration, the DS
includes more than 1,100 clinical pharmacists in 522 acute-care hospitals.
"We have the unique ability to get a
peek at what goes on in hospitals across
the country," said Thaddeus H. Grasela,
Pharm. D., director of the center and
assistant professor of pharmacy. The
network places Grasela virtually at the
bedside of patients in hospitals from
~ :•

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The network of hospital pharmacists tracks and
shares information about adverse drug reactions.
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Miami, Florida, to Anchorage, Alaska.
Currently, clinical pharmacists from six
UB teaching hospitals- Mercy Hospital,
The Children's Hospital of Buffalo, Erie
County Medical Center, Roswell Park
Cancer Institute, The Buffalo General
Hospital and Millard Fillmore Suburban
Hospital- participate in the network.
According to Grasela, one or two cases
of adverse effects from a drug over a
period of months or years in a single
hospital may not attract concern. By
combining information from hundreds
of hospitals, however, the DSN provides
a much faster way to spot problems with
specific pharmaceuticals.
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UB scientists awarded $1.5 million
in Veterans Affairs grant funding
our UB researchers at the Buffalo
VA Medical Center have received
Department of Veterans Affairs
grants totaling $1.5 million.
John Canty, M.D., associate professor of medicine , received
$606,600 to explore how nitric oxide
affects coronary artery blood flow in
conditions of underperfusion.
Alan Lesse, M.D., assistant professor of
medicine and pharmacology, received
$174,100 to explore how changes in a
surface protein on Haemophilus influenzae
affect its virulence.
Jeffrey Mador, M.D., assistant professor
of medicine, received $175,600 to investigate the causes of respiratory fatigue.
Timothy Murphy, M.D., professor of
medicine and microbiology, received
$533,700 to explore the causes of exacerbations of chronic obstructive pulmonary disease. He will also establish a
Chronic Bronchitis Study Clinic to follow patients before, during and after
exacerbations.

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~
Holmlund treats about 60 patients in
Western ew York.
The treatment, done on an outpatient
basis, involves injecting the toxin directly into the overactive muscle ,
Holmlund says. The toxin, he explains,
blocks the nerve impulse to effectively
relax the muscle.
"The nice thing about it," he notes, "is
that we can grade the weakness" to
tailor the response to each patient. The
effects ofbotulinum toxin are transient,
lasting several months - about three
each in laryngeal dysphonia and spasmodic torticollis treatments and about
six months for blepharospasms ,
Holmlund adds.
"It has been a truly wonderful experience to help patients with disorders we
previously could not help. We can finally do something positive for them,"
he says.
In addition to facilities in Albany,
Rochester and New York City, the treatment is only available at about 20 to 30
centers nationwide, Holmlund says.

vices there. She holds a master's degree
in health systems administration from
the University ofLouisville in Kentucky,
as well as both bachelor's and master's
wo new CEOs have been ap- degrees in English from orth Texas
pointed at University at Buffalo State University in Denton, Texas, and a
medical school affiliated teaching bachelor's degree in nursing from Spalding
hospitals.
College in Louisville, Kentucky.
Joseph A. Ruffolo has been appointed president and chief executive officer of The Children's Hospital of Buffalo and Evelynn G. Brown has
been appointed as the new vice president and chief executive officer for
hysicians at Millard Fillmore
Millard Fillmore Suburban Hospital.
Health System's Dent Neurologic
(For more changes at the teaching hospiGroup are one of only four groups
tals, see the cover story on Page 6.)
in New York State using botuliRuffolo previously served as vice presinum toxin to treat patients with
dent of corporate finance for Millard
dystonias.
Fillmore Hospitals, where he was reTomas Holmlund, M.D. , assistantprosponsible for financial leadership of
fessor
of neurology and an attending
Millard and its affiliated health care subat the Dent, has been using
physician
sidiaries, including corporate restructuring, medical staff development, merg- botulinum toxin successfully in patients
ers and acquisitions, programmatic de- with blepharospasms , spasmodic
velopment and expansion as well as torticollis and laryngeal dysphonia since
1991.
fiscal operations.

New CEOs appointed to head two
UB affiliated teaching hospitals

Dent physicians use botulinum
toxin successfully for dystonias

Ruffolo was credited with
playing a significant role in
Millard's financial turnaround.
The organization had lost over
$20 million in operations over
13 years before Ruffolo joined
it in 1984 and enjoyed operating surpluses in nine consecutive years after that.
Brown most recently held the
position of senior vice president and senior administrator
for Eastern Maine Medical Center in Bangor, Maine. She also
served as senior vice president
for corporate services at North
Colorado Medical Center, Inc.,
in Greeley, Colorado as well as
director of professional and
technical services and director
of nursing and patient care ser-

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Mercy Hospital'striplehead nuclear camera is
first in WNY area
ercy Hospital of Buffalo has recently acquired Western New
York's first triple-head
nuclear imaging camera.
The new camera provides
superior quality images in
shorter scan times and offers
enhanced computer capabilities to address difficult processing demands. Compared
to single-head, conventional
nuclear medicine cameras,
Botulinum toxin, injeded diredly into the muscle, blocks the nerve impulse. the triple-head is more effi-

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cient, acquires three times
the amount of information
in the same amount of time
and offers superior image
resolution.
"The recent acquisition
of the triple-head camera
will allow Mercy Hospital
to provide our patients
with the latest in nuclear
medicine imaging techniques, " said Fazalur C.
Rehman, M.B.B.S., clinical
associate professor and
chairman of Mercy's department of nuclear medicine.
The flexibility of the
triple-head camera allows
it to handle all types of
planar and SPECT studies
as well.

Suburban completes Suburban's new additions will add approximatelylOO,OOO square feet of space to the ISO,OOO-square-foot facility.
phase one of its $60
will feature a dedicated X-ray room , two cystography rooms and an exam
code room and 20 exam rooms when room . An additional six ambulatory surmillion modernization project
illard Fillmore Suburban Hospital has completed the first
phase of its $60 million modernization project, which broke
ground in September 1992, with
the opening of its orth and
East additions.
The new additions, which add approximately 100,000 square feet to the
150,000-square-foot facility, house a 20bed critical care unit, a 32-bed medicalsurgical unit, expanded emergency and
radiology departments , new cardiology
and respiratory therapy services and a
new medical library, medical records
and medical staff lounge.
Suburban's new emergency department - with 50 percent more space
than its busy 30,000-plus-visit ER -

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renovation of the original, adjacent ER
space is complete.
The 151-bed hospital's radiology department, now doubled in size, accommodates nuclear medicine, fluoroscopy
and the addition of angiography. The
department features two dedicated
mammography units, two ultrasound
rooms and two SPECT cameras.
The 20-bed critical care unit, with 10
each CCU and ICU beds, consolidates
the hospital's four intensive care beds,
four coronary care beds, a satellite pharmacy and a satellite laboratory. The new
32-bed medical-surgical unit includes
16-patient telemetry capabilities.
The new construction also adds an
additional OR room to Suburban's four ,
and three more recovery beds to its
original six. The OR suite also features

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gery beds have also been added to
Suburban's original six.
"The expansion and renovation
project will help Suburban Hospital to
meet the health care needs of
Williamsville, Amherst, Clarence and
surrounding communities well into the
future . This also provides our physicians, nurses and other medical professionals with state-of-the-art facilities to
care for their patients," said Lynn G.
Brown, vice president and chief executive officer of Millard Fillmore Suburban Hospital.
Renovation work continues on the
original building, constructed in 1974.
The $60 million project is the most
extensive modernization project in Millard Fillmore Health System's 121-year
history.

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LEADING

'
NOTHING IS CERTAIN BUT CHANGE- ESPECIALLY, IT SEEMS, IN HEALTH CARE. IN THESE TIMES OF SHIFTING POLITICAL

SANDS AND AN EXPLOSION OF KNOWLEDGE ABOUT THE HUMAN BODY AND ITS SYSTEMS, THE EDUCATION OF FUTURE

PHYSICIANS IS NEVER STATIC.

THAT'S TRUE, TOO, OF THE INSTITUTIONS WHERE THOSE FUTURE PHYSICIANS PUT INTO PRACTICE THEIR RIGOROUS

EDUCATION. SIX OF THE NINE HOSPITALS THAT ARE PART OF THE GRADUATE MEDICAL DENTAL EDUCATION CONSORTIUM

OF BUFFALO -

THE TRAINING GROUND FOR ABOUT

700 MEDICAL RESIDENTS -

HAVE NEW CHI EF EXECUTIVE OFFICERS,

ALL WITHIN THE PAST 15 MONTHS.

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�e're living in an era where both
medical education and health care
will change considerably," said
John P. Naughton, M.D., vice
president for clinical affairs and dean of
the University at Buffalo School ofMedicine and Biomedical Sciences. "The
people coming in new will bring some
new ideas, and if those ideas are worth
testing, we'll probably test them.I think
they'll contribute to positive change."
The new CEOs have come to Buffalo
from areas as diverse as Virginia and
Indiana, Texas and Maine. Their backgrounds as businesspeople and health
care administrators provide a wealth of
experience that becomes a further resource for the education consortium.
"It's something of an added learning
curve for them," Dean Naughton said.
"After all , they came here primarily to
manage their hospitals, and now they
find out that they have to work with
each other. .. . It's been a learning process in the past six months, but I think
it's been going very well. "
Buffalo Physician caught up with
these six newly appointed chief executives to ask about medical education,
running a hospital and the unique demands that New York State places on
the challenge of providing medical care.
To a person, they were enthusiastic
about the consortium's work in training medical residents. And they see
more change ahead as the hospitals and the school - cope with a new era
in health care.

sity hospital , but that structure may
turn out to be a long-term positive. The
key to it is how well we work together.
There's a tremendous give-and-take.
''I'm extremely supportive of the affiliation and want to continue to
strengthen it. It's a real opportunity for
practicing physicians, hospitals and the
university to continue to come together
in a cooperative way."
VanVorst sees Millard Fillmore as a
hospital system in a good position to
adapt to the trend toward decentralized and outpatient care. "We need to
continue to position Millard as an integrated delivery system," he said.
"If you want to cling to the anchor of
the past, this is a very troubling time. If
you see it as a bridge into transforming
our industry into even more of a positive force for society, it's a very exciting
time. It's white-knuckle at times, but
you just have to have faith that it will all
come out appropriately."

with sparking a dramatic turnaround in
Buffalo's second-largest hospital system.
Under his leadership , the formerly
money-losing system ran consistently
in the black. In addition, jennings formalized the hospitals' relationship with
the university and many of the residency programs it operates. He left Buffalo last year to become president of the
Children's Memorial Medical Center in
Chicago.
VanVorst came to Millard Fillmore
in May from San Antonio, Texas, where
he headed the multi-hospital Santa Rosa
Health Care Corp. At Santa Rosa , he
developed a long-range strategic plan
and a quality management plan. His
previous positions included president
and CEO of the Carle Foundation, in
Illinois, a not-for-profit health care holding company with hospitals and other
facilities, and vice president of operations at Methodist Hospital of Indiana.
Van Vorst has received the World
Health Organization Fellowship and
was appointed to the National Advisory
Council on Public Health Training. His
master's of business administration in
health care administration is from
George Washington University, in
Washington, D.C.
"New York is a much more regulated
state" than hts previous locations, Van
Vorst said. "It has unique nuances in
terms of how health care is delivered."
And the medical school's relationship with its consortium of hospitals,
he said, also is unusual in American
health care.
"What is exciting and, frankly, I think
is avant-garde about Buffalo, is the fact
that there is a pluralistic approach many hospitals working with the university, a joining together of community resources. I think it may be a structure that's ahead of its time.
"It starts from a level of collaboration and coordination that we have to
do, because there is no (single) univer-

Charles B. Van Vorst is the new
president and chief executive officer of
the Millard Fillmore Health System,
which comprises the 443-bed Gates
Circle and 151-bed Millard Fillmore
Suburban hospitals.
His predecessor,] an] ennings, served
for a decade starting in 1983. Active in
the community, Jennings is credited

Lynn G. Brown joined Millard
Fillmore Suburban Hospital on Nov. 3
as vice president and chief executive
officer.
She succeeds Albert L. Fritz, whose
two years at the Amherst hospital ended
when he returned to his hometown
Baltimore to establish a health care
consulting firm.
During Fritz's tenure, the suburban
hospital embarked on a major expansion necessitated by its burgeoning business in delivering babies as well as
increased services, patient visits and
occupancy that consistently approaches
100 percent. Millard Fillmore Suburban handles more than 3,000 obstetrical cases each year, reflecting its location in the youthful and populous Town
of Amherst.
Fritz redefined the hospital's approach to providing a "quality life experience" to couples at the birth of

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practice residency programs are the
core of Millard Fillmore Suburban's
role in the consortium, Brown said.
The coordination of several teaching
hospitals , she said, "certainly adds a
layer of complexity. On the other hand ,
I believe there is tremendous value for
a hospital to be affiliated with the medical school. It kind of forces everybody
to stay on the cutting edge.
"If you're there teaching residents
and have residents in the building, it
says that everybody there has to stay on
their toes. It's a very positive growth
experience, and really sets the stage for
people to stay current in the field. "
Brown said Eastern Maine Medical
Center has affiliations with Tufts University, for the teaching of pediatric
medicine, and the University of New
England, an osteopathic program. "It's
a very similar situation here ," she said.
"Obviously, the more residencies you
have, the more complicated it gets.
"It's verymucha balancing act, too, "

their children, instituting a wider spectrum of before- and after-delivery educational classes for new parents.
Lynn G. Brown comes to the hospital from Eastern Maine Medical Center
in Bangor, Maine, where she was senior
vice president and senior administrator. During four years there, she implemented a total quality management program , brought 17 patient response
teams on line and established a management development program.
Previously, Brown worked for eight
years at North Colorado Medical Center in Greeley, Colorado, serving as
senior vice president for corporate services as well as director of professional
and technical services and director of
nursing and patient care services. Her
master's degree in health systems administration is from the University of
Louisville, Kentucky. She also holds a
bachelor's degree in nursing from
Spalding College in Louisville.
Obstetrics/gynecology and family

she said. "When you commit to being a
teaching hospital, it is more work. A lot
of times it would be faster to just do
(some procedure) yourself rather than
teaching someone. But it's really the
questions, the answers and the interaction that helps us to grow. The patient,
in the long run , will benefit because
they are the recipient of having a
well-attuned medical staff."
Recognizing the hospital's "very attractive" suburban location, Brown says,
"We're all looking toward becoming a
more integrated health care system. As
health care changes and evolves, a lot
more emphasis is being placed on primary care. Family practice and obstetrics are both generally regarded as primary care practices.
"We have a very strong focus on the
health care of the future . Basically, we're
a full-service community hospital. We
want to look at more preventive medicine and the community's health in
general. "

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last October ,Joseph A. Ruffolo simply
altered his daily commute. He had
served as vice president of corporate
finance at Millard Fillmore Hospitals
since 1984.
His predecessor at Children's, john
P. Davanzo, saw the hospital come increasingly to handle high-risk deliveries; it also dominates the Buffalo market in pediatrics. During his two years
at the helm of the West Side hospital,
he grappled with a decrease in
Children's patient load attributed to
the population shift to the suburbs and
severe competition for the obstetric
market from other hospitals - most
notably, Sisters and Millard Suburban.
The resulting financial problems forced
the layoffs of about 60 employees in
1992.
At Millard Fillmore, Ruffolo played
a significant role in that system's return
to profitability. He also worked with
the medical school to establish a Department of Rehabilitative Medicine.
His previous health care administration experience includes positions
at Sheehan Emergency Hospital and
iagara Falls Memorial Medical Center. In 1990 he won the Cain, Shattuck
Co. Award, a prestigious national award
that provides the winner a fellowship
in corporate financial management at
Harvard University.
Now, Children's financial picture
has improved, and Ruffolo says the
hospital's 125 residents in all specialties of pediatric medicine are keeping
physicians up on the latest methods of
caring for the tiniest of patients.
"What (the consortium) enables us
to do is to really stay on the cutting
edge of new technologies and treatment modalities," he said. "Participating in these teaching programs allows
you to develop protocols that can monitor behaviors much more effectively
than if you were trying to do that using
When he became president and chief community hospital physicians. "
executive officer of Children's Hospital Ruffolo says he wants Children's Hos-

regulated health care environment challenging.
Here, "providers operate under a
much more regulated environment,"
Maher said. "The options on what you
can strategically do tend to be much
more limited."
He also cited the difficulties an administrator faces in a state that tightly
regulates the fees hospitals can charge.
"It's created a system where hospitals
have a difficult time maintaining financial solvency," he said. "It makes it
much more difficult for hospitals to
have the capital to restructure and retool for the future. "
About the medical school consortium, though, the new CEO is nothing
but positive. "For a hospital like Sisters,
it really opens up a lot of avenues for
being able to work with the university,"
he said.
"If you think about hospitals that are
outside the opportunities a consortium
provides, they're not able to access the
educational resources that we're able to
access. The consortium, for us, provides that opportunity, that avenue to
benefit from resources that, without
the consortium, frankly, we wouldn't
have. "
Sisters has about 48 residents in such
programs as internal medicine, obstetrics/gynecology, otolaryngology and
family practice.
The Main Street hospital's future ,
Maher said, will be "very much involved in trying to not simply take care
of the patients that arrive at our front
door, but rather reaching out to the
community and enhancing the health
status of the community. It's something
we can't do by ourselves, but only by
working collaborativelywith other providers. "

john]. Maher, Sisters Hospital president and chief executive officer, last
April became the first lay president in
the hospital's 145-year history.
The hospital, part of the Daughters
of Charity ational Health System, had
been administered for the six years
before that by Sister Angela Bontempo.
Taking office at a time when the hospital needed renovation and was facing
pressing financial problems, Sister
Bontempo helped increase the hospital
foundation's assets to more than $3
million, and directed the establishment
of new women's services, chemical dependency centers and satellite primary
care offices throughout Buffalo. She
also was the force behind the hospital's
$42 million modernization project.
Sister Bontempo left to take on other
duties in her religious order, the Daughters of Charity of St. Vincent de Paul.
Maher previously was executive vice
president of the St. Vincent Hospital
and Health Care Center, in Indianapolis, also a part of the Daughters of
Charity hospital system. There he was
responsible for day-to-day operations
at the hospital's three acute-care facilities, a regional referral center, a smaller
community hospital and a mental health
facility.
He also managed a $100 million
construction program and helped institute a program in which nurses and
other staff members play a more active
role in defining their care units - a
program that cut costs, increased satisfaction among patients, physicians and
staff and improved patient outcomes.
Prior to his six years in Indianapolis,
Maher worked in health care administration in Tacoma, Washington; Richmond, Virginia; and Chicago. He has
master's degrees in business and in
hospital administration from Ohio State
University.
He, too, finds NewYorkState's highly

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ficulties occasioned by stiff competition, fewer admissions and an increase
in the average length of time patients
stayed in the hospital. Mercy's financial
picture improved after 81 positions were
eliminated late in 1991.
In Virginia, Stanek was responsible
for all hospital operations, including
finance and marketing. His previous
experience included serving as executive vice president and chief operating
officer of Good Samaritan Hospital, in
Pottsville, Pennsylvania.
His master's in business administration and administrative management is
from St. joseph's University, in Philadelphia. His original training was in
pharmacy, at the Philadelphia College
of Pharmacy and Science, and in chemistry, at East Stroudsburg University,
East Stroudsburg, Pennsylvania.
Stanek says Eastern Virginia Medical
School worked with DePaul Medical
Center in much the same way the UB
Medical School works with the hospitals in its teaching consortium. "It really
is a major medical school," he said of
UB. "The residents have the ability to
experi~nce different environments. They

pital to reach out to the community,
"moving toward ambulatory settings
so that residents have more exposure
to ambulatory medicine. And we are
beginning to develop more outreach
initiatives in preventive medicine."
Ruffolo says Children's seeks to encourage residents to choose primary
care as a specialization, recognizing
that primary care is increasingly essential to an integrated health care system.
"I want to build Children's Hospital
as more of a regional and statewide
tertiary center for cardiovascular, thoracic and neurosurgery, hematology
and oncology," he said.
MERCY HOSPITAL

Robert V. Stanek comes to Buffalo
from orfolk, Virginia, where he was
executive vice president and chief operating officer at DePaul Medical Center.
He succeeds Sister Sheila Marie
Walsh, who had been administrator of
the South Buffalo hospital since 1976.
Sister Walsh, like many local hospital
executives, struggled with financial dif-

also have exposure to not only full-time
faculty members, but also with volunteer and part-time faculty members (at
the hospitals). There's a richness and
diversity there, and that's a major advantage that this type of consortium
approach brings to the table."
About34 residents, Stanek said, serve
in the internal medicine, physical medicine and pediatrics programs at Mercy
Hospital.
ew York, he agreed, is a unique
environment for the health care administrator. "It's driven to a large degree by
this being a very regulated state health
care environment. In Virginia it was
very deregulated. Here, reimbursement
rates are very regulated by the State of
New York; in Virginia, it's much more
a competitive situation, similar to the
Clinton managed care environment.
"I find the hospital providers in Buffalo to be very collaborative in nature,
and I find that very helpful. The level of
collaboration can help achieve a better
quality of care for the people we serve.
It becomes more cost-effective over
time."
In South Buffalo, Stanek said, "our

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overall direction is to make sure that we
are meeting the needs of the community. We try to make a commitment to
servicing employees, patients, physicians-- we look at all of those as people
whose needs we are challenged to meet."
He points to gall bladder surgery as
an example of how new technology is
radically changing the way hospitals do
business. "A few years back, you'd be in
the hospital10 days to two weeks. Now
it's laparoscopic; patients stay for a day
or two.
"We're watching the transition from
care being provided in an inpatient setting evolving to outpatient settings. It's
less expensive that way.
"And there's a very strong evolution
in the health care environment to really
deal very heavily with preventive medicine rather than just the traditional
delivery of health care. We want to
develop an integrated, seamless delivery system. We want you to have the
ability to get into the system and have
your health care needs met."

Wyoming County Community Hospital , where as CEO he guided the 102bed hospital to its first years in the
black since its founding. Hired in 1990
- a year in which the hospital lost $2.3
million- he led it to profitable years in
1991, 1992 and 1993, with no financial
assistance from the county.
At ECMC, Candino said, his mission
will be to bring the medical center into
similar financial stability, while at the
same time developing long-range plans
for the way it delivers health care.
"I think that ECMC and all the consortium hospitals have to begin looking
at the overall delivery system and the
health care community in the Buffalo
and Western ew York area, " Candino
said. "It's difficult to do, because there
are all sorts of pressures on hospitals
right now- reimbursement pressures,
health care reform pressures.
"It would be very easy for the CEO to
continually focus on what's going on
within the internal operations of the
hospital he's in charge of, but if that's all
the CEO does, then the overall world
will change, and where the medical
center fits into that will be up to someone other than the CEO. He has to
make decisions for what makes sense
for the community.
"I think we have to work together
and start making some decisions , not
only what makes sense for our particular hospital, but what makes sense for
the community."
The appointment of ECMC's new
chief executive officer was fraught with
political controversy as the hospital's
board rejected County Executive Dennis Gorski's candidate. The board has
the sole authority to hire the county
hospital's chief executive officer, but
since the county executive appoints 10
of the board's l3 members, Gorski had
argued he should have a voice in the
selection process.
With the selection process narrowed
to three candidates, Gorski had sup-

Paul Candino began work on February 14 as chief executive officer of the
Erie County Medical Center, succeeding George H. McCoy, who had led the
Grider Street facility since 1986.
McCoy resigned effective April 1 to
take a position with the government of
St. Croix, in the U.S. Virgin Islands. As
chief executive officer of St. Croix Hospital, he will oversee the rebuilding of
the hospital, severely damaged by Hurricane Hugo in 1989.
During his tenure, ECMC was named
a regional center for the care of trauma,
burns and AIDS. McCoy also is credited
with buttressing the hospital's troubled
cardiovascular surgery service and finances as it entered the 1990s. Nevertheless, it remains beset by financial
and political troubles.
Candino comes to ECMC from the

ported Sushil C. Sharma, head of
Buffalo's Columbus Hospital, over the
other two, one from Washington, D.C.,
and one from Ohio . The board rejected
Sharma, saying his experience at the
helm of tiny Columbus Hospital didn't
qualify him to lead giant ECMC. That
decision set off a firestorm of protest, as
supporters of Sharma pointed to his
exemplary record at Columbus and his
strong credentials.
Candino maintains a firmer financial footing for ECMC will ease some of
its political pressures.
"We have to gain, as an institution,
any efficiencies we can gain," he said.
"Once we do that, a lot happens and a lot
of opportunities will be presented. All of
a sudden government is not as interested
in the day-to-day operations of the medical center. As long as government is footing the bill in terms of a large subsidy,
then they're going to want to have a say.
That's their job. They're elected to serve
the taxpayers' interests.
"But once we can get beyond that,
once we can generate a gain or a breakeven situation without a county subsidy, then we'll be able to look at the
long-term picture of delivery of health
care in the Western New York area , and
work in more of a collegial environment with the other hospitals, work
toward some mutual goals."
OfECMC's part in graduate medical
education, Candino said that's "a part
of our overall mission.
"In addition to providing high-quality care at the lowest cost possible, it's
also a medical center that has the responsibility to provide teaching and
research for the overall good of medicine," he said. "Somebody has to supply physicians to the community, especially the Western ew York community and especially primary care physicians, in the future. And somebody has
to do the research and look into cures
for the future.
"I look at it as a challenge. "
+

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DANZO

It used to be fairly cut and dried. Two years of basic science. Two years of clinical experience. Then
the M.D. Those days are over.
The UB School of Medicine and Biomedical Sciences is moving steadily toward a new way of teaching
-one that stresses analysis over memorization and patient interaction over crowded lectures. Proponents
hope it will bring the art and science of medicine into more meaningful focus, providing future physicians
with cutting-edge computer skills while re-emphasizing the people skills of old-fashioned doctoring.
Many changes are being implemented or planned, but the central ones involve a problem-solving
emphasis in basic science courses, earlier introduction to clinical skills, the creation of a clerkship in family
medicine and a shift to ambulatory settings for other clerkships.
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basic science
faculty, which
he described as
"excellent."
"It's a difficult line we're
walking here,"
said Loonsk, a
1986 UB medical
school
graduate. "By
no means are
we trying to imply that what
they're doing is not superior."
The proposals not only
would make changes in the
way the basic sciences are
taught, but they would also
establish a closer link to the
clinical training that is the
core of the second two years.
"One of the ideas put forward is to focus the curriculum in the first two years
around clinical education
and experiences," said Dennis A. Nadler, M.D., associate dean for curricular and
academic affairs.
adler declined to predict the final outcome. He did say,
however, that the ideas under discussion would "drastically"
change the way medicine is taught at UB.
Bone said it would be a "significantly" different education
than the one he received when he attended the medical
school more than 20 years ago. "We had no clinical correlation," said Bone, who graduated in 1973. "We had no
interdisciplinary approach and we didn't see patients , except
for an occasional visit with a preceptor, until the third year."
The new proposals include an earlier introduction to
clinical courses and improvements to the first-year
preceptorship program. "The experiences the students had
with the preceptor program vary, and that's a concern," said
Loonsk, explaining that some students haven't had enough
contact with their preceptor.
One idea is to have students follow a single patient or
family all the way through medical school. "That's a difficult
one," Loonsk admitted.
Nadler said the second-year family medicine course might

The new approach is not so much a single effort
as a group of ideas that have evolved independently
in recent years. But many of those ideas are now
coalescing under the umbrella of the medical school's
primary care initiative. "The reason is that the forces
of health care reform and national need are such that
we don't need larger numbers of specialists, we need
larger numbers of generalist physicians," said dean
and vice president for clinical affairs john aughton,
M.D.
The medical school
hopes to be chosen by the
Robert Wood
johnson Foundation in late
spring for a $3
million grant to
help implement
the changes. If
it wins the
grant, and administration officials are
optimistic, the funds could
speed the changes, though
no one has yet put a precise
timetable on them.
Naughton said UB isn't
the only school making
such efforts, but it's at the
forefront. "We've moved a little faster than certainly most of
the eastern schools have," he said.
UB already has made some of the changes. It has started
moving medical clerkships, for instance, from hospital bedsides to ambulatory settings, such as physician offices and
clinics. It also has introduced a family medicine clerkship for
third-year students. And some basic science classes have
begun introducing problem-solving and clinical-correlation
approaches.
"The whole idea of medical school is to become a doctor
and take care of patients," said Lawrence Bone, M.D., cochairman of the school's Curriculum Committee. "That's
what we're trying to do , make doctors."
Many of the changes that are still in the proposal stage
focus on the first two years, where students traditionally
have been immersed in basic sciences.
john Loonsk, M.D. , the other Curriculum Committee
cochairman, said that while the changes are significant, they
are meant simply as improvements, not criticism of UB's

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techniques almost to the exclusion of traditional didactic teaching. UB
doesn't intend
to go that far.
"We hope to
strive for a balance ," he said.
"We believe
both are important teaching tools , and we
hope to achieve a balance. "
Rosenthal said the techniques already have been introduced as a "clinical correlations " component in
some courses, particularly
microbiology and biochemistry. The teaching often is
done in a team , with a clinical faculty member on hand
to present the case, say, of a
patient who has walked into
a doctor's office with fever
and chills. What might have
been a purely scientific discourse on bacteria is transformed into a give-and-take
exercise. Instead of- or in addition to - simply listening
to a lecture, the students find themselves pondering the
patient's chest X-ray.
"What we hope to do is give the student the opportunity
to recognize the relevance of what's being taught and give
them the discipline to ask their own questions ," Rosenthal
said.
The teaching techniques would most likely take final
shape around an "interdisciplinary medicine" course, a twoyear track that would integrate related aspects of basic
science courses now taught separately. Among the many
details still to be resolved are just which course components
to move , and where.
Rosenthal said there is no single model for what UB wants
to do with its curriculum, but medical school officials have
been exchanging ideas for several years with representatives
of five other schools, including Harvard. "This has been an
evolutionary process that comes into focus in 1994 with the
Robert Wood johnson Initiative," he said.

be expanded into the first year , using many of the
same sites, as well as some additional ones, now
used in the second-year preceptorships. Students
might spend one or two half-days a week at the same
site, following patients and seeing how a generalist
practices, Nadler said.
The second-year clinical introduction course also
might be shifted to teach first-year students interviewing and diagnostic
skills ,
said
Thomas
Rosenthal , M.D. , project director of the Robert Wood
] ohnson Generalist Initiative.
Ideally, said
Rosenthal, "by
the time they hit
the third year,
they have some
of these basic
clinical skills
developed and are able to
take better advantage of the
clinical experiences."
While clinical experience
would be accelerated and
expanded under the proposals, the approach to teaching basic sciences also is in
for some revision. Nadler
said the catch-all phrase for the change is "self-directed
learning," a central element of Harvard's New Pathway program. Essentially, it makes the student a more active participant.
"The traditional curriculum at this school is a very didactic one," Nadler said. "Students go to lectures and laboratories and are taught."
Self-directed learning is based on two techniques , casebased and problem-based teaching, which are similar. In
problem-based teaching, basic science students are presented with a question that relates to a common medical
problem, such as diabetes or cerebral palsy. The students
break up into groups, decide what they must do, research the
issue, discuss it, then present their findings . It's similar to a
seminar.
In case-based teaching, the process is about the same, but
instead of being presented with an abstract problem, students are faced with a patient case.
Nadler said Harvard's New Pathway program uses the

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find the1r own
UB was one of 18 medical schools that received
answers rather
Robert Wood johnson grants several years ago to
than be told .
search for ways of turning out more primary care
Smith, who
physicians.
attends many
Rosenthal said that the original Robert Wood
Curriculum
johnson grant of $150,000 expires in May. If UB is
Committee
among the l2 medical schools that win new $3
meetings
but is
million grants from the foundation~
, U~B~w~ou~ld!!h!av~e:._~~~~~.J._L___ 1w~..,.;
not
a
member,
"the resources to accomplish
said the combiin a couple years what would
nation of stu(otherwise) take us a much
dent-based
longer time ."
learning and earlier clinical
It would also elevate UB's
exposure should give stunational stature,
dents a greater appreciation
not only among
for what medicine is all
schools emphaabout. "The students will
sizing primary
perceive from early in their
care, but among
careers the relevance of what
those breaking
they're learning to medical
new ground in
care," he said. "Some stumedical curricudents always understood
lum innovation.
why they were learning what
While the package of prothey were learning. Other
posed changes has come unstudents
did not. "
der the primary care umpart of the apA
key
brella, there's a broader raproach is research, not the
tionale as well.
scientific laboratory kind,
"What is being proposed
but the sort that's traditionwill be good for all doctors ,"
ally done in libraries. Exsaid Cedric Smith, M.D ., a
cept now it's done more readily by computer and it's often
professor in the department of pharmacology and therapeureferred to as "accessing information."
tics .
Bone sees it in terms of fostering a "lifelong pursuit of
"There are many reasons ," said Nadler. "But maybe the
knowledge.
most important reason is we have discovered that students
"As a physician, you don't stop learning the day you
who know how to think, how to solve problems and access
graduate from medical school," he said. "It's the obligation of
information are more effective physicians than the ones who
the school of medicine to help students develop those skills
just memorize."
... in this day and age , the use of computers as a tool as well
Murray Ettinger, Ph.D. and distinguished teaching proas an instrument for learning is very important."
fessor of biochemistry, agreed.
Already, vast amounts of information are available in
"One goal is to try to give students a chance to learn more
computer data bases, many of which can be tapped through
on their own and to tie things together more on their own,"
said Ettinger, a member of the Curriculum Committee. "Up
the HUBNET system operated by the medical school and its
consortium hospitals. And electronic medical records will
to now, a lot of medical school education in this school and
most schools is an awful lot like undergraduate education,
become more common, replacing traditional written records .
"The electronic medical record is going to have terrific
where people just go to lectures and take exams."
The new curriculum may be more like traditional graduramifications in patient care," said Loonsk, who is the medical school's director of medical computing.
ate education, where students are expected to conduct their
Some proponents envision storing a patient's full medical
own research , then present their findings and argue their
history, right down to the X-rays , in computer data bases
conclusions in seminar discussions. In short, students would

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from which the information can be easily retrieved
and transferred. That could also have tremendous
implications for clinical researchers, who currently
must go to hospital record rooms and wade through
stacks of patient charts.
UB has been trying to familiarize medical students with computers and make them aware of the
machines' potential since 1986, Loonsk said. It is
one of the few schools that
require computer training,
though that's done now as a
component of biophysics in
the second year.
One of the
curriculum
proposals now
under discussion would create a first year,
first semester
course devoted
to medical computing.
"Actually, here at Buffalo,
we're way ahead of the game
compared to many schools
because of the HUB NET system," said Loonsk.
Through HUBNET, students and faculty can get into
data bases like MEDLINE,
where they will find information pertinent to both clinical
care and research. Many of the data bases contain complete
articles, and even textbooks are available on-line.
"One of the problems with medicine for a long time was
that it was becoming increasingly specialized, partly because
there is so much information, it was difficult for the generalist physician to stay current in all these areas," Loonsk
noted.
Not any longer.
"The implication to medical school," added Loonsk, "is
that we should teach people how to access the information
well."
Specialists, of course, will always be needed. And physicians will always have to carry a lot around in their heads. But
with medical knowledge expanding daily, some medical
educators have come to the conclusion that it's better to
stress thinking over memorization, because physicians who
are well-versed in the principles can now more readily look
up the detailed information they need for a specific case. And

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that information will be
more current
than something
they learned
years ago.
"In the past
we taught students much
more to memorize," said Susan
Schwartz,
M.D., a Curriculum Committeemember. "Butit'simpossible to define anymore
a body of knowledge they
should have by the time they
leave medical school."
With problem-solving
and research skills, she said,
"they can become experts."
The 25-member Curriculum Committee has
been discussing many of the
changes for several years
and is just beginning to take
the broad themes to the faculty at large. Before implementation, proposals must
be approved by the Faculty
Council, then go to course coordinators for more detailed
development. Loonsk said they probably would not take
effect until the 1995-96 academic year, at the earliest.
Some significant related changes already have occurred,
however. The biggest is the family medicine clerkship for
third-year students. A major part of the Robert Wood johnson
Generalist Initiative, it was approved by the Faculty Council
in 1993 and will be instituted with the 1994-95 academic
year.
At the same time, the traditional clerkships are shifting
away from hospitals toward ambulatory settings.
"In medicine, the big change that we introduced over the
past year was a four-week block of ambulatory medicine,"
said Schwartz, who is clerkship director for medicine.
There are related goals. As medicine in general has shifted
toward more ambulatory care, the educational experience
for students in hospitals has narrowed. They've been meeting
only the sickest patients, limiting their bedside interactions
with patient and physician alike.

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solution, she added , means that many students will take part
two of their boards in senior year before finishing the full
medicine and surgery clerkships. "That may be a problem,"
she said.
The shift to ambulatory settings also has some students
worried. "It's not a concern on my part, but for the students
I think it seems a lot more intensive in the hospital setting,
and they need to be reassured that they're learning as much
in the ambulatory setting," Schwartz said.
When the first group of students in the new ambulatory
medicine rotation took their exam last fall, they did as well
as previous groups, she noted .
The ambulatory emphasis also means lining up new
training sites and more community-based volunteer faculty .
"That type of educational experience is basically one-onone," said Rosenthal. "It does represent a challenge to the
departments of pediatrics and medicine to develop that
volunteer faculty. "
Other challenges lie ahead. For one thing, curriculum
planners must decide which components of basic science
courses should be integrated into the new interdisciplinary
and problem-based approaches, and which should be left
separate. There is consensus on the concepts - "We're
trying to teach the science basic to medicine, rather than
teaching basic science," said adler- but the devil is in the
details.
Also, some faculty members are uneasy with the uncertainty of the whole situation and the implication that the old
ways were a failure .
Naughton said that while UB is at the forefront of medical
curriculum innovation, "most medical schools are going to
make these same kinds of changes in the next few years ."
"It will require a lot of faculty cooperation," he added. It
is possible the new teaching approaches could take time from
faculty who already are stretched between classes and their
own research. Then again, the approaches could be easier to
teach, since they delegate more of the responsibility for
learning to the students.
Either way, things are changing.
"It will put a lot more stress on the primary care facultythey'll have to participate in courses they never thought
about participating in before," said Rosenthal. "It will put the
basic science faculty in a position where they'll have to
interact more with clinical faculty ... it'll require change on
both our parts, and change is stress."
Ettinger agreed that faculty will be affected. "It's a different kind of teaching," he said.
But, he added , "I think it may be less painful than people
think."

"The student wasn't getting a chance to do their own
personal history and physical the way they were supposed
to," said Schwartz.
In a doctor's office or a clinic, Rosenthal said, students
encounter patients "who present earlier in the disease process and with a condition that is not acutely life-threatening.
So your diagnostic work-up is done not only at a different
pace, but it's done with a different approach."
Besides encouraging more students to choose primary
care, he added, it will give future specialists more exposure
to generalist physicians, which can only help interactions
between the two groups.
As faculty members ponder curriculum, some administrators have been thinking about the admissions side of
things . adler said there have been efforts to identify demographic characteristics of medical school applicants most
likely to choose primary care careers. "There is some literature on the subject, though it's pretty scarce," he said. "There
is a sense that people from rural backgrounds are more likely
to choose generalist medicine and return to rural areas ."
But Thomas]. Guttuso, M.D., assistant dean for admissions, said the effort is limited. "We're looking for those
people who have the personal qualities that we think will
make them become outstanding practicing physicians," he
said. "If it fits primary care, fine. But it doesn't have to be
primary care."
Meanwhile, said Guttuso , the number of applicants has
increased from a low of about 2,250 in 1988 and 1989 to
about 3 ,600 for the 1994-95 class. "There's definitely been an
increase in the number of people applying who don't have
pure scientific backgrounds," he said. "But still, the vast
majority of the pool is scientifically oriented."
While there is a sense of enthusiasm about all the changes,
a lot of dust is still to settle.
"These things come at a price, and they don't come easily,"
said Naughton, noting that introduction of the new family
medicine clerkship resulted in scaled back third-year
clerkships for medicine and surgery.
The family medicine clerkship will be seven weeks, while
medicine and surgery are being reduced to eight weeks from
the previous 11 weeks. To compensate, students will take
four weeks of a new Medicine 2 and Surgery 2 in the fourth
year .
"I was not happy about it," said Schwartz. "Not at all." She
said planners considered a "screw everyone" solution that
would have cut a week off all clerkships, but that would have
disrupted the system of teaming students up with residents
and interns on four-week rotations .
"It was really a fierce battle for a year," Schwartz said. The

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$7.5 million establishes new center
ENTERPRISE WILL CONCENTRATE ON DEVELOPING AND
MANUFACTURING REHABILITATIVE ASSISTIVE DEVICES

he University at Buffalo has re- ogy Evaluation and Transfer "expands Assistive Technology and project direcceived a five-year, $7.5 million significantly the capabilities of the Cen- tor of the new initiative. The co-direcgrant from the National Institute ter for Assistive Technology, already a tors of the project are William C. Mann,
on Disabilities and Rehabilitation visible leader in the field.
professor and chair of the UB DepartResearch to establish the first na"It promises to increase our collabo- ment of Occupational Therapy and ditional center for advancing new ration with consumer-based agencies rector of the Center for Assistive Techassistive devices from the inventor's and private businesses in the commu- nology, and Kenneth ]. Ottenbacher,
workshop to the manufacturer's assem- nity and nationally. It offers a promising professor of occupational therapy and
new model of cooperation between uni- associate dean of the School of Health
bly line.
The Rehabilitation Engineering Re- versity, business and public interests." Related Professions.
search Center on Technology EvaluaThe new center will help close the
Five to 10 devices per year- items
tion and Transfer is a collaboration be- - supply-demand gap in assistive devices that likely would not reach the public
tween the Independent Living Center of existing nationwide, notes joseph Lane, otherwise - are expected to become
Western New York, an agency that as- associate director of the Center for available to people with disabilities as a
sists people with disabilities;
result of the center's work.
the Western New York Tech"We plan to bring into the
nology Development Center,
marketplace products that
Inc. (TDC), a corporation that
will make a difference in
helps create, expand and dipeople's lives," Lane adds.
versify technology-related
"We hope to reach the inbusiness in Western New
ventor working in the family
York; and UB's Center for
garage, as well as the estabAssistive Technology, a
lished designer.
multidisciplinary group that "Really helpful products
provides research, education
often never see the light of
and service in the field of
day because many designers
assistive technology.
and inventors don't have reThe center, which began
sources to develop their ideas
operating last fall, screens
and make them marketable,
prototypes for new assistive Above, Steve Bauer, director of research and development for the center,
and don't know how to link
works on an electronic data acquisition system. Below, Dale Johnson, design
devices from across the
up with the manufacturer,"
engineer associate, works on a powered mobility simulator.
United States, selects those
he said. "On the other hand,
with the most market potential, evalumanufacturers often lack knowledge
ates and refines them and establishes
about consumer needs and product repartnerships with commercial firms to
quirements. Our new center will promanufacture and market the products.
vide the resources and become that missG. Alan Stull, dean of the UB School
ing link."
of Health Related Professions, in which
Lane notes that the "military research
the Center for Assistive Technology is
and development of the past decade
housed, says the Rehabilitation Engigenerated a wealth of new technologies
neering Research Center on Techno!that are pending declassification. They

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hold great promise for assistive technology applications.
"The facilities now at UB, along with
resources in Toronto, Rochester, Pittsburgh and Cleveland, make this region
uniquely positioned to become the national center for research and manufacturing in assistive technology. We are
definitely the leading region in the field."
The Center for Assistive Technology
currently houses the national Rehabilitation Engineering Research Center on
Aging, which develops and evaluates
assistive devices for disabled older
adults.
The Center for Assistive Technology
also encompasses the Developmental
Disabilities Assistive Technology Institute, which designs and produces lowdemand assistive products; Project
LINK, a national clearinghouse that connects consumers who need assistive
products with appropriate device manufacturers; Rehabilitation Technology
Services, which designs and builds customized seating and positioning devices,
plus a wide array of services for people
with sensory, physical and cognitive
impairments.
The new center uses a five-stage evaluation process to ensure resources are
expended on products with market
value. Prototypes are analyzed by technical, user and marketing groups at each
stage, and are either withdrawn or advanced, depending on the results of the
collaborative evaluations.
Organizers expect the center to be
self-sufficient within five years, generating future operating funds through a
percentage of the revenues from sales of
devices licensed to manufacturers, partial ownership of some patents and fees
for services charged to some inventors
and corporations.
A new not-for-profit company will
eventually take over the center's technology evaluation and transfer functions.

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Above, Johnson welding in a lab at the center.
The UB Center for Assistive Technology will continue new device research
and development as well as grant procurement to fund the manufacture of
"orphan" products- devices that would
substantially enhance the lives of those
who could use them, but that have little

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commercial value to manufacturers.
A 10-member board of directors with
representatives from national consumer
associations, private corporations, research
centers and technology-transfer agencies
oversees the work of the new center.
-

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UB begins joint study of addiction

that 75 to 90 percent of the alcoholic
population never enter an alcohol treatment program," Blane explains. "Thus,
UB JOINS WITH RESEARCH INSTITUTE ON ADDICTIONS there is a strong need for populationbased studies like the ones we will conTO ESTABLISH ALCOHOL RESEARCH CENTER
duct."
RIA will conduct a study of why
he School of Medicine and BioThe grant will create approximately some alcoholics seek treatment while
others do not, and why some alcoholics
medical Sciences and the Buffalo- 30 new jobs.
"This is the first NIAAA Alcohol Re- appear to recover without treatment.
based Research Institute on AdTrevisan notes the grant offers a
dictions (RIA) have received a joint search Center dedicated to studying the
$8 million grant from the National clinical and medical epidemiology of unique opportunity for alcohol researchInstitute on Alcohol Abuse and alcoholism. The new center adds an ers and clinical epidemiologists to work
Alcoholism to establish the nation's first important, substantive direction to al- together to conduct research into
Center for the Clinical and Medical Epi- cohol research in this country," Blane alcohol's relationship to chronic dissays. "These studies will significantly ease.
demiology of Alcohol.
"The study concentrating on coroHoward T. Blane, Ph.D., RIA direc- expand our knowledge of the natural
tor, will direct the new center and Marcia history of alcoholism and the relation- nary heart disease will look in detail at
Russell, Ph.D., RIA senior research sci- ship between alcohol use and health drinking patterns- not just the amount,
but the way people consume alcohol entist, will serve as scientific director. disorders.
"Most of what we know about alco- as possible risk factors," he adds. "We
Maurizio Trevisan, M.D., chair of social
and preventive medicine, will direct re- holism is based on studies of alcoholics will also look at the interaction between
in treatment, but it has been estimated alcohol and other nutritional factors."
search conducted at UB.
The UB study on alcohol and
The grant will fund three major
~!l!!fJ~IF~~;;;~II!I'I-,~Itll!!~ lung cancer will be the first to conresearch studies and one pilot protrol for possible confounders such as
gram that will run concurrently
over the next five years. The renutritional status and passive smoking - a particularly important facsearch programs will study the epitor to consider, Trevisan notes, since
demiology oftreated and untreated
alcoholism, the epidemiology of
a great deal of alcohol is consumed
alcohol and coronary heart disease
in smoky bars.
and the epidemiology of alcohol
Other UB researchers involved in
and lung cancer. The pilot prothe project includejo Freudenheim,
gram will involve the development
Ph .D.; james Marshall, Ph.D .;
of a computer-based geographic inManavela M. Desu, Ph.D.; jeffrey S.
formation system on alcohol conSchwartz, M.D.; Donald Armstrong,
Ph.D.; Elisa V. Bandera, M.D.; Terry
sumption to serve as a basis for
Pechacek,
Ph.D.;johnE. Vena, Ph.D.;
further epidemiological study. The
Lucy Campbell, Ph.D., and Paula
grant also provides funds for a naMuti, M.D.
tional conference on alcohol epiAdditional RIA researchers indemiology to be held in its fourth
year and the establishment ofa blood
cludeGerardj. Connors, Ph.D.; Kenand specimen bank that will allow
neth E. Leonard, Ph.D., and Michael
~
~ future researchers to explore the role
R. Frone, Ph.D.
~
j of genetic markers and individual
RIA is a research institute affiliated
~ susceptibility and to assess the interwith the New York State Office of
u
action between alcohol consump- The NIAAA Alcohol Research Center will be the first to study
Alcoholism and Substance Abuse Sertion and these markers.
vices.
the clinical and medical epidemiology of alcoholism.

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�···-·--·-·--·---·-------------·----------------·-·---------- ----··----·-·-·············· a

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1993 is strongest yeM

ever for school's James
Platt White Society
he James Platt White
Society capped its
strongest membership
drive ever last October
with a special reception at the Park Country Club.
Membership in the organization, which recognizes
donors to the School ofMedicine and Biomedical Sciences
of $1,000 or more, rose to
more than 180 alumni, faculty and friends.
Organized in 1986 on the
medical school's 140th anniversary, theJames Platt White
Society is a distinguished
leadership organization based
on the values and principles
of James Platt White, M.D.,
one of the founders and a
former dean of the medical
school and a pioneer in the
field of obstetrics. White's
vision, intellectual vigor and
moral courage represent the
qualities of the society's membership and leaders.
Gifts to the medical school
by members of the society
have helped fund biomedical
and clinical research, provide
scholarships, purchase stateof-the-art laboratory equipment and maintain innovative programming.
Members of theJames Platt
White Society for 1993 include:
Dr. Bruce Abramowitz
Dr. Kenneth Alford

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Dr. Kenneth Z. Altshuler
Dr. Richard Ament
Dr. William S. Andaloro
Drs. Kevin and Elizabeth Barlog
Dr. jared C. Barlow
Dr. Ronald E. Batt
Dr. Ralph T. Behling
Dr. David A. Berkson
Dr. Richard A. Berkson
Dr. and Mrs. Willard H. Bernhoft
Dr. Theodore Bistany
Dr. john C. Bivona, Jr.
Dr. Willard H. Boardman
Dr. Martin Brecher
Dr. and Mrs. Harold Brody
Dr. Melvin M. Brothman
Dr. Robert L. Brown
Dr. August A. Bruno
Dr. Elaine M. Bukowski
Dr. Ivan L. Bunnell
Dr. David W. Butsch
Ms. janet F. Butsch
Dr. john L. Butsch
Mr. David N. Campbell
Dr. icholas]. Capuana
Dr. Peter A. Casagrande (deceased)
Dr. and Mrs. Norman Chassin
Dr. and Mrs. joseph A. Chazan
Dr. Michael E. Cohen
Dr. Robert]. Collins
Dr. Donald P. Copley
Dr. and Mrs. William R. Cromwell
Dr. Daniel E. Curtin
Dr. Richard Daffner
Dr. Peter S. D'Arrigo
Dr. Roger S. Dayer
Mrs. Carlo E. DeSantis
Dr. Edward Diao
Dr. Stuart L. Dorfman
Dr. Sterling M. Doubrava
Dr. Ronald I. Dozoretz
Dr. George L. Druger
Dr. Kenneth H. Eckhert
Dr. Robert Einhorn
Dr. and Mrs. George M. Ellis
Dr. Alfred S. Evans
Dr. john A. Feldenzer
Dr. Donald M. Fisher
Dr. jack C. Fisher
Dr. john W . Float
Dr. Thomas F. Frawley
Dr. Vincent]. Fuselli
Dr. Richard R. Gacek
Dr. B. joseph Galdys
Dr. Ronald F. Garvey
Dr. john W . Gibbs
Dr. Gerard Guerinot
Dr. Thomas]. Guttuso
Dr. Ralph R. Hallac
Dr. joseph V. Hammel
Mrs. Gilda L. Hansen
Dr. Reid R. Heffner, Jr.
Dr. Orvan W. Hess
Dr. William J. Hewett
Dr. joseph M. Hill

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Dr. Fredric Hirsh
Dr. john M. Hodson
Dr. Robert M. jaeger
Dr. Kenneth L. jewel
Dr. Stephen T. joyce
Dr. james R. Kanski, Jr.
Dr. julian R. Karelitz
Dr. john P. Kelly
Dr. Kenneth Kim
Dr. and Mrs. Paul S. Kruger
Dr. Marie Leyden Kunz
Dr. and Mrs. Marvin Z. Kurlan
Dr. Francis]. La Luna
Dr. RobertS. LaMantia
Dr. Gordon R. Lang
Dr. Andre D. Lascari
Dr. Dana P. Launer
Dr. Won Yub Lee
Dr. Sanford Leff
Dr. Eugene V. Leslie
Dr. Laurence M. Lesser
Dr. Paul A. Lessler
Dr. and Mrs. Harold]. Levy
Dr. jack Lippes
Dr. Hing-Har Lo
Dr. Thomas A. Lombardo, Jr.
Mrs. GraceS. Mabie
Dr. Milford S. Maloney
Dr. David L. Marchetti
Dr. Don L. Maunz
Dr. Michael A. Mazza
Dr. Margaret McAloon
Dr. Charles]. McAllister
Dr. Margaret P. McDonnell
Dr. Harry L. Metcalf
Dr. Francis C. Mezzadri
Dr. Merrill L. Miller
Dr. Eugene R. Mindel!
Dr. joseph F. Monte
Dr. john D. Mountain
Dr. Arthur W. Mruczek, Sr.
Dr. Richard L. Munk
Dr. Richard]. Nagel
Dr. Masao Nakandakari
Dr. Richard B. Narins
Dr. john Naughton
Drs. Robert and Lillian Ney
Dr. Charles R. Niles
Dr. john D. Norlund
Dr. Benjamin E. Obletz
Dr. Patrick L. O'Connor
Dr. Thomas P. O'Connor
Dr. Carrie P. Ogorek
Dr. Yasuyo Ohta
Dr. Elizabeth Olmsted
Drs. Dean and Donna Orman
Dr. johnS. Parker
Dr. and Mrs. Robert]. Patterson
Dr. orman L. Paul
Dr. Clayton A. Peimer
Dr. Victor L. Pellicano
Dr. james F. Phillips
Dr. Daniel A. Pietro
Mr. R. Willis Post
Dr. Richard A. Rahner

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Dr. Bert W. Rappole
Dr. Albert C. Rekate
Dr. Frank R. Riforgiato
Dr. Charles j . Riggio
Dr. Richard R. Romanowski
Dr. and Mrs. Charles H. Rosenberg
Drs. Robert Smolinski and
Claudia Fosket
Dr. Albert G. Rowe
Dr. jacob D. Rozbruch
Dr. Eric]. Russell
Miss Thelma Sanes
Dr. Michael A. Sansone
Dr. Robert N. Schnitzler
Dr. David S. Schreiber
Dr. joseph I. Schultz
Dr. Roy E. Seibel
Dr. Molly Seidenberg
Dr. Elizabeth G. Serrage
Dr. john B. Sheffer
Dr. john E. Shields
Dr. Timothy S. Sievenpiper
Dr. Roger M. Simon
Miss Alice Simpson
Dr. Arthur C. Sgalia, Jr.
Dr. Raymond M. Smith, Jr.
Dr. Morton Spivak
Dr. john E. Spoor
Dr. john]. Squadrito
Dr. Richard J . Sternberg
Dr. William Sternfeld
Dr. Eugene M. Sullivan
Dr. Michael A. Sullivan
Dr. MichaelS. Taxier
Dr. Charles S. Tirone
Dr. john P. Visco
Dr. Franklin E. Waters
The estate of Mrs. Pauline E. Watson
Dr. and Mrs. Arnold Wax
Dr. and Mrs. Harold F. Wherley
Dr. james]. White, Jr.
Dr. Gary]. Wilcox
Dr. james S. Williams
Dr. Richard G. Williams
Dr. and Mrs. Marvin Winer
Dr. john R. Wright
Dr. Gregory E. Young
Dr. Wende W . Logan-Young
Dr. Syeda F. Zafar
Dr. Franklin Zeplowitz
Dr. and Mrs. David C. Ziegler

Editor's Note: While every effort is made to ensure the accuracy of this listing, omissions and
misprints may occur. This report
lists all members between October 24, 1992 and October 22,
1993. If you have any questions,
comments or concerns, please call
Michael E. Benzin, Acting Director of Annual Giving, at (716)
645-3312. Thank you.

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Sesquicentennial committee begins events planning
MEDICAL SCHOOL FOUNDING ALMOST

150 YEARS AGO

MARKS UNIVERSITY AT BUFFALO'S BEGINNING

ith a little more than two years
before the University at Buffalo
and its School of Medicine and
Biomedical Sciences celebrate
the 150th anniversary of its
founding, the History of the
Medical School Committee is already
busy planning celebrations and events
to commemorate the historic occasion.
Composed of representatives from
both the medical school and the university at large, the committee meets
monthly as a whole; its task forces focus
on specific aspects of the Sesquicentennial Celebration.
In the planning stages are a symposium series, the medical school's annual
Spring Clinical Day, various medical
school and community-wide exhibits
featuring medical school memorabilia,
a special sesquicentennial logo and the
Annual Meeting of the American Association for the History of Medicine,
scheduled from May 8 to May 12, 1996.
The group is also working on anumber of special publications, including A
Medical History in Buffalo 1846-1996:
Collected Essays, A Pictorial History of
the Medical School, Selected Writings of
Austin Flint and an alumni directory.

Douglas Bacon, M.D.

SCHOOL OF MEDICINE

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Committee members include:
Harold Brody, Ph.D., M.D., Co-chair
Professor, Department of Anatomical
Sciences
Ronald E. Batt, M.D., Co-chair
Clinical Associate Professor,
Department of Gynecology-Obstetrics
joyce Vana, Ph.D., Secretary
Clinical Assistant Professor, Social and
Preventive Medicine

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Assistant Professor, Department of
Anesthesiology
James Bono, Ph.D.
Assistant Professor, Department of
History
Ivan Bunnell, M.D.
Clinical Professor Emeritus,
Department of Medicine
Leon Farhi, M.D.
Distinguished Professor, Department
of Physiology
Shonnie Finnegan
University Archivist
David Gerber, Ph.D.
Professor, Department of History
Nanette Tramont Kollig
Editor, Buffalo Physician
Richard Lee, M.D.

UNIVERSITY AT BUFFALO

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Professor of Medicine, Pediatrics and
Obstetrics
john Naughton, M.D.
Vice President for Clinical Affairs
Dean, School of Medicine and
Biomedical Sciences
Carole Smith Petro, Ph.D.
Associate Vice President for University
Advancement
Office of the Vice President for University Advancement and Development
jack Richert, Ph.D.
Associate Dean for Alumni Affairs
Mildred Sanes
Lilli Sentz
Curator, History of Medicine
Collection

Library of Anatomy and Cell Biology
Dedicated -John Naughton, M.D., vice
president of clinical affairs and dean of the
School of Medicine and Biomedical Sciences,
speaks at the dedication of the school's
anatomy and cell biology library last
October. At left, Irene DeSantis, widow of
Carlo DeSantis, Clarice Bernhoft and Dr.
Willard Bernhoft, after whom the library is
dedicated, look on.

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· · · · ··· · · · · · · · ·a

Medical school memorabilia
sought for pictorial history
o celebrate the l50th anniversary
ofits founding, the medical school
will publish a pictorial history.
Already being compiled, the history will feature articles and
memorabilia about the school, its
students and the historical events that
have made it what it is.
Connie Oswald Stofko, former Buffalo
Physician editor, who will edit and compile the publication, asks for help from
anyone who might have a contribution
to it:
"We need pictures, lots and lots of
pictures, to make our pictorial history
shine. We're looking for anything visual: photos, paintings, drawings, commencement programs, award certificates, perhaps even an antique that we
could photograph. We need pictures
from every time period , but we expect
we'll have the hardest time finding things
from the 1800s.
Don't send any original! We'd hate
for an heirloom to get lost in the mail.
Describe to us what you have, or perhaps photocopy it. Please include the
names of people in the picture, the date,
wh ere it was taken and any other information you have. If you can't identify
the picture, maybe we can help.
Send the information about your
picture to:
Connie Oswald Stofko
Editor, Pictorial History of the
Medical School
History of Medicine Collection
Health Sciences Library
South Campus
3435 Main Street
Buffalo, New York 14214
Please remember to include your
name, address and telephone number
so we can contact you .

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Items already
from the Pictorial
History of
Medicine
Collection, to be
published for the
Sesquicentennial
Celebration in
1996. Above, Dr.
Roswell Park
performing
surgery, circa
1898. At left, the
University of
Buffalo's 1894
football team.

Pictu re guidelines:
Photographs: Any size, color and
shape is fine. We can have a print made
from a slide. Photos from programs and
other publications could be copied. Photos from old newspapers might work.
Paintings, drawings: Oil paintings,
charcoal sketches, pen and ink drawings, pastels and other artwork are all
possibilities. Maybe you have artwork

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of an old building or a sketch of a piece
of equipment or the readout of some
pioneering piece of equipment.
Other: Look for programs from lectures, commencements or other ceremonies; award certificates; pins or buttons, or perhaps early items used in
your field.
Thanks, but we don't need yearbooks.
We've got those."

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�THEN-NOW

Anesthesiology at the University at Butfalo:
FROM ITS ROOTS IN 1913 TO TODAY , US'S DEPARTMENT OF ANESTHESIOLOGY
HAS MADE NOTEWORTHY CONTRIBUTIONS TO THE SPECIALTY

was a pivotal year in
the history of medicine both locally and
nationally. On May
l l , 1846 the University of Buffalo School
of Medicine was founded. Almost five
months later, on October 14, 1846, William Thomas Green Morton used the
vapors of sulfuric ether to anesthetize
Gilbert Abbott for the removal of a jaw
tumor in the first public demonstration
of surgical anesthesia.
One hundred forty-eight years later,
Paul R. Knight, Ill , M.D. , Ph.D., chairman ofUB's Department of Anesthesiology, oversees a branch of the medical
school with more than 80 faculty members. The anesthesiology department
supports 52 residents and fellows in six
clinical sites scattered across the Buffalo
metropolitan area, administers anesthetics , cares for patients with pain and
manages critical care. Its anesthesiologists actively investigate problems in
basic science and clinical and historical
research, as well as give lectures in basic
science and clinical demonstrations for
the medical students.
The Department of Anesthesiology
has not always been so substantial. It
originally was part of the Department of
Surgery; its first appointment, John
Henry Evans , was nominated in 1913 by
the world renowned surgeon, Roswell
Park, as an assistant in anesthetics. Over
the next 40 years, Evans would bring
anesthesiology in Western New York
and the University of Buffalo to international prominence as he developed the
country's first department and residency

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training program .
While remaining in
active clinical practice all his professionallife, Evans also
published 29 papers
over the length of his
career in the leading
journals of his day .
John Henry Evans
was born on September 24, 1876 to
Welsh immigrant parents in the Southern Tier community of Freedom, New
York. He learned English at the age of 10
when his family moved to Machias and
his father established a general store. He
attended the Ten Broek Academy in
Franklinville and graduated from Ithaca
High School.
Evans spent six years in the Merchant Marine before resettling in Western New York and enrolling in the University of Buffalo School of Medicine.
After graduating with honors in 1908 at
the "advanced" age of 32, Evans spent
four years at The Buffalo General Hospital as a house officer, giving anesthetics
as part of his duties .
Evans returned to Machias in 1912 to
set up a general practice. But he returned to Buffalo within a year after his
brother was killed in a train accident.
Evans' interest in the administration
of anesthetics and his work with Roswell
Park during his days as a house officer
led to his faculty appointment. From
then until the First World War, he was
paid $2 per student for teaching anesthesiology. On May 15, 1917, the chairman of surgery promoted Evans to instructor in anesthetics.

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The First World War interrupted his
academic career, when he was commissioned as a captain in the United States
Army Medical Corp . He returned to
Buffalo after his discharge in 1919 and
began to resurrect both his academic
and political career by becoming active
in the organizations of the specialty.
During the 1920s, Evans helped establish two societies devoted to advancing the then-fledgling specialty of anesthesiology. In 1922, he was elected president of the Board of Governors of the
International Anesthesia Research Society, an organization over which he would
preside for the next 20 years. The group's
mission was to promote scientific inquiry into anesthesiology across the
world. In 1923, the Eastern Society of
Anesthetists was founded by Evans and
two nationally prominent ew York City
anesthesiologists,] ames Gwathmey and
Adolf Erdmann , to promote anesthesiology along the Eastern seaboard. Evans
presented a paper at the ftrst meeting of
the society entitled "Blood Pressure
Guides and Safety in Anesthesia. " In
1927, he was elected president of the
Associated Anesthetists of the United
States and Canada, the only national
anesthesiology organization at the time .
The July 1927 issueoftheBritishjoumal
of Anesthesia was dedicated to Evans
and listed his many accomplishments.
In 1928, Evans was elected as the
Eastern Society's president and helped
present a bust of Morton commemorating the first public demonstration of
ether anesthesia to the Massachusetts
General Hospital. Photographs of the
event were published in Current Re-

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�THEN-NOW

his career. Convinced that oxygen injected subcutaneously could improve
wound healing and eliminate arthritic
pain and improve function, Evans spent
long hours testing his theories. Years
after, former medical students still remember Evans' demonstration of the
technique.
In addition to pain management,
Evans was embroiled in a scientific debate over how much oxygen could safely
be used to treat pneumonia. Evans advocated the use of a high enough inspired oxygen concentration to abolish
cyanosis - a radical thought for the
day. Many others felt that permanent
lung damage would occur when oxygen
was inspired in concentrations greater
than 60 percent. Evans clearly demonstrated this was not the case, and developed an apparatus for oxygen administration by face mask that today would be
recognized as continuous positive airway pressure ( CP AP). When Boston's
Coconut Grove Night Club burned in
1942, Evans was called in as a consultant to administer supplemental oxygen
to the victims of that fire.
The University of Buffalo should be
proud of its long tradition in anesthesiology and its first chairman,] ohn Henry
Evans. His attitude and his efforts have
made possible much of what has become routine academic practice in the
81 years since Roswell Park made his
initial appointment.

Above, Evans, shown ot left ot his office in Mochios, New York. Below, the University of Buffalo
medical school classes of 1907 through 1911. Evans is the first person in the second row at left.

-

searches in Anesthesia and Analgesia, the

Department of Anesthesia; full recognition of anesthesiology as a medical specialty had materialized in Buffalo. Residency training in the field was initiated
that year when Rose Lenahan accepted
a position as hospital assistant in anesthetics (the equivalent of resident today) at The Buffalo General Hospital.
Research into the effects of oxygen
captivated Evans for the last 20 years of

only American medical journal devoted
to the field at the time, and Evans was
pictured among the leaders in the field .
In 1932, he was appointed professor
of anesthetics. Four years later, a publication of Evans' originated at the Department of Anesthesia. The 1938 edition of the University of Buffalo Bulletin
cited Evans as professor and head of the

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BY

DOUGLAS

BACON ,

M.D .

About the author: Douglas Bacon, M.D., is an
assistant professor in the department of anesthesiology and director of resident education at
Roswell Park Cancer Institute.
The author would like to thank Chris Densmore
and Shonnie Finnegan of the University at Buffalo
Archives, Alfred S. Evans, M.D. and Ann Stewart
(Dr. Evans' children), Richard N. Terry and
Patrick Sim of the Wood Library-Museum of
Anesthesiology fo r their help in preparing this
manuscript.

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Members of the IH study sections
are selected on the basis of their demonstrated competence and achievements
within their scientific fields. Achievements taken into consideration include
the quality of research accomplishments,
publications in scientific journals,
achievements and honors.

UB professor authors several
sections for the Merck Manual
ames B. Lee, M.D., UB professor of
medicine has updated the prostaglandins, thromboxanes and
leukotrienes sections for the recently published 16th edition of
The Merck Manual of Diagnosis and
Therapy.
Lee, who is an alumnus of]efferson
Medical College in Philadelphia, is director of the Erie County Medical
Center's hypertension program.
Lee is one of 300 scholars and specialists who have contributed to The
Merck Manual.

Schimpthauser elected to head
medical education research group
rank Schimpfhauser, Ph.D., UB assistant dean and director of educational evaluation and research, has
been elected president-elect of the
Society of Directors of Research in
Medical Education.
The Society of Directors of Research
in Medical Education, which
conducts and promotes medical education research and
acts as liaison and
consultant to other
medical groups, is
composed of professionals in the
field from U.S. and
Canadian medical
schools.
Schimpfhauser,
a 1965 UB graduate, has been active in the society
for nearly two decades, serving as
membership committee chair in
1991 and treasurer
in 1992.
Schimpfhauser's
research in medical education has
included topics on Frank Schimpfhauser, Ph.D.

Murphy chairs NIH subcommittee
imothy F. Murphy, M.D., professor of medicine and microbiology, has been appointed chair of
the Bacteriology and Mycology
Study Section, Subcommittee 2,
Division of Research Grants for
the National Institutes of Health.
Murphy is chief of the infectious diseases divisions of the medical school,
the Buffalo VA Medical School and Erie
County Medical Center.
He co-developed a vaccine with the
potential to provide immunity against
middle ear infections and was recognized as Niagara Frontier Inventor of
the Year for 1992 by the Technical Societies Council of the Niagara and iagara
Frontier Patent Law Association.
Director of the UB microbial pathogenesis graduate group, Murphy heads
two five-year projects totaling $2.5 million in funding from the National Institute of Allergy and Infectious Diseases
to study organisms that cause childhood middle ear infections and adult
lung infections.

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cancer education, student career choice
and decision making and most recently,
on the use of standardized patients for
the assessment of clinical competence.
An associate professor of social and
preventive medicine, he holds master's
and doctoral degrees from Ohio State
University. He administers program
evaluation activities for the School of
Medicine and Biomedical Sciences and
is the coordinator of the third and fourth
year academic programs. He also chairs
the Association of American Medical
Colleges' mini-workshop program and
is a member of that organization's national planning committee.
He has published more than two
dozen articles in professional journals
and has made presentations at more
than 30 conferences in the U.S. and
abroad.

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····················· · ················ · ··· · ·····················[!]
lii'J

Spring Clinical Day agenda set

AGENDA

he Medical Alumni Association
has set the agenda for its 57th
Annual Spring Clinical Day, to be
held Saturday, April 30, at the
Buffalo Marriott.
This year's program - Medical Education Into the Next Centuryfeatures Jerome P. Kassirer, M.D., '57, as
its keynote speaker. Kassirer, who received the Distinguished Medical Alumnus Award in 1992, is editor-in-chief of
The New England journal of Medicine
and professor of medicine at Tufts University School of Medicine. He also lectures at Harvard University. Kassirer
will deliver the Stockton Kimball Memorial Lecture, "Clinical Reasoning:
Teaching It and Learning It."
The program, designated for up to
3.5 hours of category credit toward the
Physician's Recognition Award of the
American Medical Association and 3.5
prescribed hours by the American Academy of Family Practice, will present
new approaches to the teaching of medicine. Faculty will explore ways to improve patient-physician communication
and investigate its impact on the practice of medicine. Medical informatics
and its effect on medical education will
also be discussed, as well as the use of
standardized patients in medical education.
In addition to Kassirer, the faculty
includes John W. Loonsk, M.D., '86,
UB's director of the office of medical
computing and assistant professor of
biophysical sciences; RichardT. Sarkin,
M.D., coordinator of UB's teaching effectiveness program and director of pediatric medical student education; and
Paul::; L. Stillman, M.D., provost and
dean of the Medical College of Hampton
Roads, Eastern Virginia Medical School,
Norfolk, Virginia.

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7:30a.m. Registration and continental
breakfast
8:15a.m. Welcoming Remarks
Robert Reisman, M.D., '56
President, Medical Alumni Association
John Naughton, M.D.
Vice President for Clinical Affairs
Dean, School of Medicine and
Biomedical Sciences
8:25 a.m. Introduction to the day's
interactive program
Frank T. Schreck, M.D. '79
Program Chairman
8:30 a.m. "The Science of Listening"
RichardT. Sarkin, M.D.
9:15a.m. "Information at Clinical Fingertips: Moving Beyond the Promise of
Medical Informatics"
John W. Loonsk, M.D. , '86
10 a.m. Coffee break and exhibit review
10:30 a.m. "The Use of Standardized
Patients for Teaching and Assessment"
Paula L. Stillman, M.D.
11:30 a.m. Business meeting
Noon Annual Medical Alumni Luncheon
and Stockton Kimball Memorial
Lecture "Clinical Reasoning:
Teaching It and Learning It"
Jerome P. Kassirer, M.D. , '57

Andersen '47,and Zizzi '58,
lauded by UB and ECMC
urray N. Andersen, M.D., '47,
and Joseph A. Zizzi, M.D ., '58,
were honored for their long-time
work at Erie County Medical
Center.
Officials from the School of
Medicine and Biomedical Sciences as
well as county and hospital officials,
cited the physicians last year at the
hospital's annual Springfest dinner
dance. The event is held to benefit employee education.
Andersen is former chief of thoracic

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and cardiovascular surgery at ECMC.
He also served two years as president of
the medical-dental staff at the former
E.]. Meyer Memorial Hospital.
Zizzi is director of clinical cardiology. He has also served as assistant medical director, acting medical director,
medical director and deputy medical
director at the hospital.

Celebri-tees- Stephan Commins '74, and Jan
Nathanson '74, at last October's Walt Disney
World's Pro-Am Golf Classic.

LincoiT '88,authors JAMA article
orah Lincoff, M.D. , is one of the
co-authors of a "Letter from Havana - 'Outbreak' of Optic and
Peripheral Neuropathy in Cuba?"
published in the July 28, 1993
edition of the journal ofthe American Medical Association.
The article concerns a disorder first
recorded by Cuban physicians in January 1992 and subsequently spread
throughout Cuba. Lincoff and fellow
authors Jeffrey G. Odel, M.D. , and
Michio Hiano , M.D., of the College of
Physicians and Surgeons of Columbia
University, studied 20 patients ranging
in age from 19 to 63 years afflicted by
the disorder, the symptoms of which
include decreased vision and sensory
symptoms (paresthesia, burning and
dysesthesia) predominantly in the feet.
Lincoff currently is a neuro-ophthalmologist at Buffalo General Hospital.

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Q
to Grenada and then I got accepted to
UB," he says.
Deciding to pursue pediatrics, he
trained at The Children's Hospital of
Buffalo and eventually accepted the position of medical director of the hospital's
Roberto Clemente Health Center on
Buffalo's West Side.
Prior to his arrival, a physician would
spend three hours a day seeing patients
at the center. "My idea was to offer
continuity in a full-time position there
and set up a system where we could have
a nutritionist and social worker and
build up the community so that our kids
could stay out of the hospital emergency room," Coyne explains.
The effort was a success. When he
started at the center in 1988, patient
visits averaged 4,000 per year. By the
time he left last September, the annual
total had grown to 22,000.
Last fall, Coyne accepted a position
with Niagara Falls Memorial Medical
Center, taking on much the same challenge he did at Clemente. He was put in
charge of the Kids Clinic at the Hamilton
B. Mizer Primary Care Center- a place
where a physician came in three or four
days a week for three hours at a time.
Coyne quickly added two full-time physicians, a nurse practitioner and a social
worker.
He credits Memorial Medical Center
President Timothy J. Finan for taking
the initiative in extending continuity of
care at the primary care site that has just
opened 10 new pediatric rooms and has
since been renamed Memorial Pediatrics.
"Forty-seven percent of the community in Niagara Falls is on public assistance. Most of those children do not
have a physician. Tim Finan felt that
was not appropriate and that we needed
to do something different," explains
Coyne.
Services provided by Memorial Pedi-

Prtest doctor, advocate for the poor
FROM NORTHERN KENYA TO NIAGARA FALLS ,
JACK COYNE '85 , TREATS THE UNDERPRIVILEGED

ost people follow one vocation
at a time. Not Jack F. Coyne,
M.D. He is both pediatrician and
priest. The 1985 graduate of the
School ofMedicine and Biomedical Sciences, however, considers
himself primarily in social work.
"There are those who feel that the
priesthood is more sacramental. I honestly believe that the role of the priest is
to be a social worker," he says.
This view proved to be a renegade
attitude with the Church in St. Louis
where he was a graduate student in the
late 1960s. So Coyne became part of a
small group of fellow seminarians who
decided to start a new religious community.
"There was a full-page article in
Newsweek when we made the break in
1968 for doing things differently- not

dealing with the liturgy so much as
dealing with inner city problems,"
Coyne recalls.
Coyne added another vocation at the
time as the group used music to express
its work in the inner city, forming a
folk-rock quintet known as "The Mission" that made appearances on national TV talk shows hosted by Dick
Cavett, Steve Allen and Mike Douglas.
The quintet also made an album for
Warner Brothers Records with Mary
Travers of "Peter, Paul and Mary."
In 1981 - 10 years after he was
ordained a priest- experiences in Cambodia, Haiti and Borneo convinced
Coyne that he needed a knowledge of
medicine to continue his work with the
poor. "Because of those experiences, I
applied to medical school and I got
lucky. I had my airplane ticket set to go

Jatk Cayne, M.D., and two very satisfied patients, Jeremy and Harvey Brundidge.

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In 1984, Coyne switched from the Roman to Eastern rites, joining the Greek Orthodox Church.
Coyne observes, adding, "To get the
right mental health services, to get the
right counseling, to get a child who's
eight or nine through the system now
and get the help he or she needs will
help prevent them from becoming a
painful survivor at 30. This is really a
goal of mine and something that child
advocacy is dedicated to as well. "
Coyne added yet another vocation in
1987 when he became a husband and
then a father. Having a continuing problem with the church law of celibacy, he
switched from the Roman to Eastern
rites in 1984, joining the Greek Orthodox church, which allows priests to be
married.
"There is no relationship in my mind
between priesthood, service and celi-

atrics include well child care, sick care,
immunizations, sports and school physicals, lead testing, birth control, teenage
counseling, 24-hour emergency coverage and supportive services for physical
and sexual abuse.
In fact , Coyne is the medical director
of child advocacy teams in Erie and
Niagara counties that investigate sexual
abuse. "We see about three children a
week who are sexually abused ," he says.
He is pleased with Erie County's commitment to revamp a floor of the Prudential Building at Delaware Avenue
and Allen Street as an advocacy center
for young sexual abuse victims.
"I find that a real expression of pediatrics because many of these children
are forgotten - not just medically,"

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bacy. I still think that might change in
the Catholic church but I'll probably be
long gone when that happens. That
brought me to where I am today - to
keep my priesthood but be able to get
married and have a family," he states.
Two years ago , Coyne fulfilled a lifelong dream and journeyed to Africa to
set up a clinic in the bush of Northern
Kenya for the nomads . "We did some
HIV testing and worked with the (missionary) nuns there to create some medical services that could be performed on
a regular basis ," he explains.
It was a brief visit before his return to
Buffalo. "I always thought I would eventually stay in Africa to work but as I grew
up and had more responsibilities, such
as a family , going to Africa wasn't as
easy. My way of expressing the same
need was to work in the inner city here, "
Coyne declares .
It has truly been a multi-vocational
road for this Long Island native with a
lifelong commitment to working with
the poor. "I always wanted to be a priest
but I didn't want to be in a parish," he
concludes.
Instead of administering in a parish,
jack Coyne has acted as a shepherd of
health care continuity in communities
where such enrichment has been rare.
And that's good for both the body and
soul.
-

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CORRECTION
In the last issue of Buffalo Physician,
Dr. Franklin Zeplowitz' name was
inadvertently omitted from the 1993
Reunion Class donors. Dr. Zeplowitz
should have been included with his
1958 graduating class. Our sincerest
apologies!

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it is about the only occupation for the
people. A coffee picker may earn 11
quetzales ($1.70) a day," Schaefer said.
Approximately 2,500 people live in
the village, with about 25,000 more in
surrounding villages and coffee plantations, Schaefer said. Transportation is
difficult in the mountainous region.
"Patients often have to walk many hours
or days to reach the hospital," he added.
The Hospital de la Familia receives surgical patients from all parts of Guatemala and the surrounding areas of southern Mexico, El Salvador and Honduras.
Schaefer said the most prevalent diseases there are malnutrition, respiratory ailments, gastrointestinal infections,
congenital malformations and traumatic
injuries. The region's infant mortality
rate is approximately 80 percent, although a substantial improvement in
that figure has been reported over the
past five to 10 years in the area served by
the Hospital de la Familia.
Schaefer was accompanied by operating room nurse Karen Kumar and
operating room technician Geraldine
McGuire. During their two-week stay in
Nuevo Progresso, they performed 140
eye surgeries.
The ophthalmology team was part of
a larger medical group that covered a
variety of specialists, including
otolaryngologists, general surgeons, OBI
GYN and general plastic surgeons. This
was Schaefer's second visit.

Carolyn Bessette, M.D., in NASA's zero-gravity simulator.
surgeries as well as defibrillation and
mechanical ventilation.
Bessette has completed a flight
surgeon's training course offered at the
johnson Space Center and is currently
pursuing an aerospace medicine residency.

Carolyn Bessette completes NASA
aerospace medicine fellowship
arolyn Bessette, M.D., a recent
medical school graduate, recently
completed a NASA aerospace medicine fellowship at the johnson
Space Center in Houston.
She was one of four senior medical students selected to participate. The
four-week intensive program included
lectures on topics such as cardiovascular reflex responses to microgravity,
pharmacodynamics in zero-gravity, controlled ecological life support systems
aboard a space station, the mechanisms
of decompression sickness, vestibular
adaptation to space flight and muscular
atrophy and adaptation to microgravity.
The fellowship also included zerogravity simulation flights as well as visits to NASA's Space Station Freedom
mock-up's medical operations module.
The unit is equipped to perform minor

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Daniel Schaefer '81, volunteers in
Guatemala with medical team
aniel P. Schaefer, M.D., '81, director of the ophthalmology section
at St. joseph Hospital, was a member of a volunteer medical team
that traveled to the Hospital de la
Familia in Guatemala last spring
to administer services to the poor.
About 2,500 people live in the Nuevo
Progresso, a mountain village about 170
miles northwest of Guatemala City.
"The town lies at an altitude of about
2,500 feet in a nearly impenetrable rain
forest. This is a coffee growing area and

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The Strasenburgh Planetarium, in Rochester,
New York, was the site for a recent Medical
Alumni Association reception.

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�Dear Colleague,

Donnica Moore '86, honored by
Amertcan medical women'sgroup
he American Medical Women's Association (AMW A) honored
Donnica L. Moore, M.D., '86, at
last year's 78th annual meeting,
"Women Promoting Women's
Health: Prevention Through Research and Education." Moore was presented with the Calcium Education Nutrition Award, sponsored by Proctor and
Gamble Pharmaceutical
Company. The
award is presented annually
to the AMWA
member who
has done the
most to educate
physicians ,
medical students and the
lay public about the importance of
osteoporosis and treatment.
Moore is currently the director of
medical education at Sandoz Pharmaceuticals. She has spearheaded development of the Sandoz osteoporosis computer education program, a comprehensive, state-of-the-art, multimedia
self-directed learning program designed
for medical students. She has also been
involved in developing AMWA's master
faculty training program in osteoporosis
and in establishing the Sandoz
postdoctoral fellowship in bone metabolism.
The AMWA event also marked the
first time the association featured a UB
School of Medicine and Biomedical Sciences alumni reception at its annual
meeting.
Moore, who is also AMWA regional
governor for New York and New] ersey,
organized the reception.

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THEY SAY YOU NEVER CAN - B U T IT'S STILL FUN TO TRY
sis my tradition, I returned to
my roots in New York City for
New Year's.
I never enjoy the ew Year's
rituals, since traditionally by
12:45 a.m., you've been asleep
for 10 minutes with a pointy
noisemaker protruding from
your pocket.
For the past 10 years, my
friends from med school and I
have always celebrated the "Third
Alternative" party (the first alternative is the usual New Year
activity and the second is to stay
home or go camping in Central
Park) .
At this particular party ,
watches are checked at the door
and we have random countdowns
on the dance floor and show a
video loop of the ball dropping
throughout the evening (from
1961, of course, since Dick Clark
had the same formaldehyde look
then he has today). The goal is to
avoid the mechanized rituals of the holiday and still have fun .
A trip toN ew York is never complete
without a trip to the old neighborhood.
People there still know me because I
went to medical school.
The first person I see is the man

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across the street with the clever mustache and stretch pants with bass and
treble control.
"Hi, how's it going in CaliF AWNYA?
Are you still interning?"
He doesn't ask if I'm an intern, but if
I'm still interning. I believe the verb

In thi.s old, entrenched,
working-class
jewish neighborhood,
everyone has a
doctor who is the ,,best"
in their field.
"intern" means to confine or impound,
especially during a war- which, come
to think of it, is not unlike what it feels
like to be an intern and go three and a
half years without sleep.
This guy (for the life of me I have no
idea who he is or how he knows me)

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next says to me, "Tell me something ... "
(Already I know I'm in trouble.) "My
wife sprained her ankle. What's good
for it? Dr. Marvin Schanker on the radio
says milk is good for this sort of thing. "
I'm thinking Dr. Schanker certainly
should know since he learned so much
about medicine while earning his
Ph.D. in communications.
Against my better judgment, I
continued this conversation and
told him milk will help a broken
bone but not a sprain.
He broke in with, "Oh, what
do you know. Dr. Schanker has
been around a long time- you're
young yet."
Dr. Schanker may have been
around a long time, but so has
Charles Manson and I don't usually ask him for advice on ethics
cases. Maybe it's time for Dr.
Schanker to be interned.
In order to gain brownie points
with me , everyone from the old
neighborhood tells me about
the doctors they know. "My
daughter-in-law's brother is
married to a doctor. He is
doing very well as a plumonologist"- which I believe
is either a French expert on
ball-point pens or an author-

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�jewish neighborhood, everyone has a
doctor who is the "best" in their field.
When pressed as to why their doctor
is the best, they tell you, "everyone says
so," and, "he's so busy you have to make
an appointment to make an appointment. He's the best 'eye man' in Brooklyn. "
The truth is, nobody knows how well
their doctor did in medical school. How
many even look to see where the doctor
went to school. Does anybody actually
know how well their doctor did in biochemistry? obody looks!
I have a friend, a podiatrist, who
actually hangs his dog's pedigree on the
wall.
For his patients, he's the best "foot
man" in Bensonhurst.
I even went back to the hospital
where 10 years ago I spent
my first days on
the ward. I
recalled

my first time in the hospital wearing my
white coat that came out of the package
five minutes earlier with eight other
things, including two stethoscopes, an
eye chart and a rectal thermometer key
chain. I looked more like a roofer on the
way to an insurance inspection.
At this point, I don't know anyone
who carries that much equipment. But
when you're a student and you don't feel
like a doctor, you need to at least look
like one (orTrapperjohn). I recall standing there with all this equipment on
while residents whirled by picking off
stethoscopes and eye charts saying 'can
I borrow this , can I borrow that?' I felt
like a gingerbread man Christmas
morning. Of course they
never returned
any of the
equipment,

so after a half hour I was picked clean
down to my boxer shorts ready to see
my first patient.
I felt so awkward. I was 22 years old.
I wasn't shaving yet, and here I was
doing procedures on people, examining
patients. You can never say touching or
feeling in the medical profession; they
teach you very early on it is always
"examining, probing, palpating," never
"touching." That's too offensive.
But it felt good to see old friends and
colleagues and to see that I'm not the
only one unbuttoning my pants while
sitting down to dinner because my pants
are shrinking. Happy ew Year.
Stu Silverstein, M.D., president
of Stondup Medicine Seminars
of Son Francisco, California,
lectures nationwide on
humor in medicine.

ILLUSTRATION BY JAY LINCOLN

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search fellow at the Buffalo Institute of Fetal Therapy.
Karamanoukian received
the award , presented last summer at the society's annual international meeting in Washington, D.C. , for his research
combining nitric oxide and
surfactant for the treatment of
diaphragmatic hernias in newborns. Last year marked the
first time ever the Society of
Pediatric Research presented
the award to a surgeon.
Karamanoukian's research
suggests combining nitric oxide with surfactant may lower
the mortality of newborns with diaphragmatic hernias and significantly
decrease morbidity. Further prospective clinical trials to examine the effect
of the combined modality are planned.
Karamanoukian is working in the
laboratory of Philip Glick, M.D., assistant professor of surgery and Children's
pediatric surgeon.

Frances Nesti, M.D.

Children'sfellow wins crttical care
medicine research training award
he Society of Critical Care Medicine In Training Award has been
awarded to Frances Nesti, M.D., a
fellow in critical care medicine at
The Children's Hospital of Buffalo
and UB's department of pediatrics.
The award recognizes excellence in
critical care research. Nesti was chosen
specifically for her research presentation in the area of perfluorcarbon liquid
ventilation.
Nesti received an engraved plaque
and $2,000.

Annual Incoming Residents
Week set for June 13 -18
The School of Medicine and Biomedical Sciences will hold its annual Incoming Residents Week
Monday through Saturday, June
13- 18.
Approximately 150 residents
will participate in the program
about communication skills, teaching skills and issues in medicine
such as advanced directives , documentation and medical records.
The residents will also receive life
support and advanced life support
training.

Nitric oxide/surtactant research
garners national research award
he 1993 National Residency Research Award , presented by the
Society of Pediatric Research, has
been awarded to Hratch
Karamanoukian, M.D ., a general
surgical resident of the department
of pediatric surgery at UB and The
Children's Hospital of Buffalo and re-

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Lalley,Ph.D~ '74,tapped to head
HIT student center for the deaf
eter Lalley, Ph.D., has been selected to head the Center for Baccalaureate and Graduate Studies at
the ational Technical Institute
for the Deaf ( TID), a college of
Rochester Institute of Technology
in Rochester, New York.
Lalley, a 1974 graduate of the school
of medicine's doctoral program in human genetics, was named to the position last]une. The recently established
center is a comprehensive, student-oriented service that offers such programs
and services as academic advising, tutoring, notetaking and interpreting as
well as pre-baccalaureate discipline-related courses.
A geneticist, Lalley has achieved national and international prominence.
From 1985 to 1991, he was chairperson
of the International Committee on Comparative Gene Mapping. He has served
on numerous national and international
advisory panels and has written more
than 80 research journal articles. He is
on the editorial board of Clinical Biotechnology and has been subject area
editor of Genomics. He is a former editorial board member of the journal of Experimental Zoology and Cytogenetics and
Cell Genetics as well as a reviewer for
numerous other publications.
The NTID is the world's largest technological college for deaf students. It
was created by Congress and is funded
primarily by the U.S. Department of
Education.
NTID represents the first effort to
educate large numbers of deaf students
within a college campus planned principally for hearing students. More than
1,100 deaf students from across the
United States and other countries study
and live there.

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�·························································································[! ]
Rehabilitation Center in Clarence,
New York, where he served as
medical director. His portrait will
be displayed in the center to honor
his many years of dedicated service. Dr. Paolini was instrumental in the creation of the Broth-

ROSARIE BENDER ' 20, is retired and living in Fort Lauderdale, Florida. Dr. Bender, who
was one of the first women plastic surgeons, practiced plastic

and reconstructive surgery for
50 years. She is the only living
member of her class.

ers of Mercy's 40-bed rehabilitation unit. He plans to enjoy retirement with his wife, Emily, eight
children and three grandsons.

writes,
"Surviving: two bypasses, cataracts. Keeping busy, would like
to see more entries from my class.
Where are you? How are you?"

David S. Ba[hman '47

BERNARD S . STELL '46, of
Sun City, Arizona, informs us

retired surgeon, is a columnist
for several newspapers, and the
author of a recently published
book, Thoughts and Musings of
an Arkansas Country Doctor. He
also co-authored the book ,

MAX A. SCHNEIDER '49, received the Silver Key Award from
the National Council on Alcoholism and Drug Dependence
for "outstanding service in the
field of addiction medicine."

HENRY H . HAINES '33,

that his article "Stereomacrography - The Water Droplet
Lens" appeared in the December 1993 issue of Stereoscopy,
published by the International
Stereoscopic Union.

DAVID S . BACHMAN '47 ,

a

with his family and three little
grandsons.
HERBERT W . SiMPK INS ' 53 ,

of West Orange, New jersey, retired from practice in December.
PAUL

L.

of Tarzana,

California, retired last]uly after
38 years of practice in internal
medicine.

Breaking the Smoking Habit.

informs us he is now fully retired
and plans on spending more time
BURTON STULBERG ' 52 ,

FERDINAND A. PAOLINI '47,

retired in December from the
Brothers of Mercy Nursing and

HERBERT A .
'55 ,

LEONHARDT

of Florham Park, New jer-

sey, informs us that he retired in
1993. He has six grandchildren.
J . SULLIVAN '55 ,

writes, "Still working full time
with my practice restricted to
forensic psychiatry. My wife,
Carol, and I recently purchased
a new, large motor home; we are
enjoying traveling throughout
the West, Canada and Mexico in
it."

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V
o 10% IRS Penalty On Withdrawals Before Age 59-1/2
V
o Forced Distributions At Age 70- 112
V
Flexibility To Fit Your Changing eeds

B

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' 54 ,

lished in the Fall1993 PHAROS
(the AO medical honor society
magazine). His paper explains
the 10 biblical plagues.

WILLIAM

DAVID HERTZ '52 ,

WEINMANN

wrote a paper, "The Tenth Plague
-Deathofthe ewborn? " pub-

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was re-

CAPTAIN ELIAS ROSENBLATT

director of clinical services in

elected to a second term as treasurer of the Minnesota Medical
Association.

'68 , writes , "I have been living

the department of radiology at
the University of Iowa. He has
six children and one grandchild.

ERICK REESER ' 56 ,

in Potomac, Maryland for almost
10 years now, long enough to
appreciate some of the better
parts of the Washington, D.C. ,
area, and to avoid all the rest. My
wife, Ruth, is administrative director of physical medicine and
orthopaedics at Suburban Hospital in Bethesda. Our son , Jeremy, is in his junior year at the
Bullis School. Our daughter ,
Alison, graduated from there a
year ago and is a sophomore at
Kenyon College. Their brother,
Michael, graduated from Cornell
in 1991 and is now working in
the hotel appraisal business in
Miami. I'm a captain in the Navy
medical corps , currently assigned as the director of the
Naval Medical Doctrine Center
on the Marine Corps Base at
Quantico, Virginia. This assignment followed my graduating
from the Naval War College. The
center develops, analyzes and
tests the doctrine of the utilization of medical assets in support
of Naval, joint and combined
(i.e., NATO) operations. It's very

WILLIAM E . ABRAMSON '60 ,

writes, "On July 31 , 1992, Iretired after 28 years as a staff
psychiatrist at Sheppard Pratt
Hospital in Towson , Maryland. I
have remained in private practice , with my office in the hospital , and on the courtesy staff. I
love my new boss !"
presented
papers on attention deficit disorder in young adults at the University of Massachusetts MediHARRIS FAIGEL '60 ,

cal Center, American College
Health Association. He is president-elect of the New England
Chapter of the Society for Adolescent Medicine. His granddaughter, Madeline, was born
January 10, 1993.
RONALD S . MUKAMAL '64 ,

retired from private practice and
moved to Baltimore, where he
works part time.
writes,
"Although I returned to Ghana
in 1968, I have tried to keep in
touch with a few classmates over
the years. Notable among these
are Charles Ladoulis , Michael
Taylor and Steve Scheib~r. From
1968 to 1978, I taught epidemiology and control of tropical
endemic diseases in the Department of Community Health of
the Ghana Medical School. I
joined the World Health Organization in 1978 and served as a
senior epidemiologist at the
FRED K . WURAPA ' 64 ,

B

u

a

Irving S. Kolin '65
Tropical Disease Research and
Training Centre in Ndola, Zambia. Since 1986, I have been reassigned to the WHO Regional
Office as the Regional Adviser
on Control of Parasitic Diseases."
AUGUST

J . D ' ALESSANDRO

' 65 , retired in 1992 from the state

of Connecticut after 25 years. He
is medical director of Catholic
Family Services in Danbury,
Connecticut, and a psychiatrist
with the New York State Department of Mental Retardation .
IRVING S . KOLIN ' 65 , successfully completed the examination of the American Board of
Adolescent Psychiatry for certification in adolescent psychiatry
last May 20. Dr. Kolin is board
certified by the American Board of
Psychiatry and eurology and
in the past year has also successfully completed examination for
added qualifications in geriatric
and addiction psychiatry. He is
also certified by the American
Society of Addiction Medicine
and the American Board of Quality Assurance and Utilization Review.

0

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exciting work. Not only are my
clinical and operational experiences utilized , but so are the
academic and communication
skills learned in undergraduate
and prep school years. "
IAN

M .

SCHORR

' 69 ,

of

Englewood , New Jersey , announces a new grandson , born
February 4, 1993.
is professor of radiology and pediatrics and vice chairperson and

WILBUR L. SMITH ' 69 ,

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RONALD H. BLUM '70,

was

appointed deputy director of
NYU's Kaplan Cancer Center.
His wife, Diane, is executive director of Cancer Care , Inc.
ROBERT DIBIANCO '72 ,

and

his wife, Joan, announce a new
addition, Regina Marie DiBianco,
born August 1, 1993. The family
now consists of David , l2;JohnMichael, 8; Regina Marie, 1/2!
DR .

ROBERT

KROOPNICK

was elected a fellow of the
American College of Physicians
in January 1993. Board certified
in both internal medicine and

'72 ,

geriatric medicine, he practices
in Randallstown , Maryland.
is director of the Englewood Hospital hemodialysis unit. He has a
12-year-old son and two collegeage sons; one attends the University of Vermont and one attends the University of Arizona.
RALPH R . HALLAC '73 ,

RICHARD LEE '74 , writes he
has been named medical director of Sierra Summit Rehabilitation, an outpatient facility in
Reno, Nevada. A fellow of the
American Academy of Neurology and certified by the American Academy of Pain Management, he was recently appointed
a fellow of the Royal Society of
Medicine, London , U.K. Dr. Lee
has also been involved in locum
tenens work for the past three
years in clinical neurology.

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- !
n

'

ton and his wife, Katie, are the

R ICHARD

I

A. WOLF '82 , writes,

proud parents of a son, James

"still in cardiology at Grand

Cody, born in October 1992.

Forks Clinic in Grand Forks,
North Dakota." He wonders if
anyone knows where Rob

MARK 5 . BORER '80 ,

is presi-

Dudek, Roger Beneitone and

dent of the Psychiatric Society of

Ivan Baumel! are?

Delaware and co-founder and

PATRICK E . RYAN , JR ., '83 ,

medical director ofMeadowwood

is currently in fellowship in

Intensive Treatment Options.
GASPERE

Barlow Lynch '77

C .

cardiothoracic surgery at SUNY

GERAC I '80 ,

Syracuse. He is married with

writes that he is currently em-

three children: 4 l/2 years, 21

ployed by Capital Health Sys-

months and 4 months.

tem as medical director of pri-

NORA MEANEY-ELMAN '84 ,

mary and urgent care. He reBARLOW LY N CH '77 ,

is presi-

dent-elect of the Washington
Urological Society. Dr. Lynch is
a clinical assistant professor of
urology at Georgetown and

cently received board certification in medical management in
addition to board certifications
in family practice and emergency
medicine.

George Washington University.
He lives in Silver Spring, Mary-

JAMES B . BRONK '81 ,

has

land, with his wife, Pauline, and

been installed as the 67th presi-

son, jason.

dent of the Solano County Medical Society. He is a partner in a

ORESTES G . ROSABAL '77 ,

is

the

Southern

Medical

Association's state councilor for

and Vacaville, California.

Florida. In October, he attended
the association's 87th Annual
Scientific Assembly in New Orleans. Dr. Rosabal maintains a
private practice in orthopaedic
surgery in Hialeah, Florida.
TERENCE

CHORBA

' 79 ,

writes, "I received an M.P.A.
from Harvard's JFK School of
Government in June before returning to the National Center

' 81 ,

an

had a great time in Cambridge. "
BRUCE J . NA U GHTON '79 ,

is

returning to Buffalo as chief of the
division of geriatrics at The Buffalo General Hospital. Dr. Naugh-

B

u

a

0

Electrodiagnostic Medicine

Megan Elizabeth, on June 25 ,

meeting. Robin is a neurologist

1993. She continually amazes
us, as well as her brothers, Daniel

in Pittsburgh; Sarah, Maria and I

and Ryan."

Arbor, respectively. "
is as-

practice-in D.C.,Buffalo,and Ann

DE I DRE GREENE '86 ,

writes ,

sistant director of psychiatric

"Accepted a part -time faculty po-

emergency services at Montefiore
Hospital, Bronx, New York.

sition with Egleston Children's

was

Atlanta. We celebrated the birth

elected chairperson of the Chesa-

of our third child, Timothy Elvis

peake Bay Alcohol and Substance

Dixon, in August 1993. "

Abuse Program Advisory Board.

CARLOS M .

ophthalmologist in Amherst,

Hospital at Emory University in

ISADA '86 ,

re-

com-

cently joined the staff of the Cleve-

new company, Energy Systems
Associates, specializing in elec-

pleted a five-year general surgery residency at St. Luke's-

land Clinic Foundation in the de-

tromagnetic medicine and bio-

Roosevelt Hospital in Manhat-

His wife, Loretta Isada, is in pri-

FRANK

New York, recently founded a

LACQUA '85 ,

partment of infectious diseases.

logical hazards consultations. He

tan and a one-year colon-rectal

vate practice in Akron, Ohio, as

and his wife, Diane, announce the

surgical fellowship in Houston,

a noninvasive cardiologist.

birth of their son, Michael) oseph,

Texas. He is in private practice

GLENN

on May 29, 1993. He joins proud

in Brooklyn and Staten Island,

Lithonia, Georgia, and his wife,

sisters, Erica and Sarah.

New York. He has married Eva

Carla Hackett Paris, announce

for Injury Prevention and Control at CDC. My family came and

at the American Association of

DENISE M . DAVIS '85 ,

ology group based in Fairfield

DAV ID J . RODMA N

writes, "My husband, Richard
Elman '78, and I had a daughter,

CAROL W E INSTE IN '84 ,

private practice diagnostic radi-

James B. Bronk '81

GERALD HARSTER '82 ,

was

PARRIS

'87 ,

of

Acosta and resides in Brooklyn.

the birth of a daughter, Stephanie

writes ,

Delyse Parris, on September 17,

JON M . WARDNER '85 ,

appointed director of laborato-

R.

ries at jeannette District Memo-

"There was an impromptu Class

1993. Dr. Parris is a rheuma-

rial Hospital, near Pittsburgh,

of '85 mini-reunion in

Pennsylvania. He has two sons,

leans this October. I enjoyed run-

tologist in private practice at the
Gwinett Arthritis Center; his

Ryan, 10, and jesse, 6.

ning into Maria Labi, Robin

wife is administrator at Grady

Con wit and Sarah Murray White

Hospital.

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�[! ] ·············································· ····································· · ····
and
his wife, Marcia, announce the
birth of a daughter, Rachel, in
DAVID ROSENBLUM '87 ,

December 1993. She joins her
brother, Daniel, 4. Dr. Rosenblum
is chief of medical staff at Gaylord
Hospital in Connecticut and codirector of its spinal cord injury
unit. Active in clinical research,
including clinical trials in multiple sclerosis, he also holds appointments at Yale and Columbia-Presbyterian Medical Center.
will

R ICHARD GILBERT '88,

M ICHAEL HALLETT '89 ,

was

recently appointed associate
medical director for adult psy-

CARLOS C . ALDE N '39, died
January 14, 1994. The Army's
most decorated surgeon, he was
a senior psychiatrist at Buffalo
Psychiatric Center for more than
a decade before his retirement in
1976.

chiatry at Brylin Hospitals. Dr.
Hallett completed his psychiatric residency at Erie County
Medical Center. He also maintains consulting privileges with
Millard Fillmore Health Systems
and has established a private
practice. In addition to general
adult psychiatry, his interests
include obsessive/compulsive
disorders, mood disorders, anxi-

NAT HAN I EL J . P U LVER '48 ,

Lidia Palcan '90

join the Buffalo Medical Group
after completing a urology residency at Georgetown Medical

ety disorders, dual diagnosis and
schizophrenia.

Center in June. He has three
children: Ricky, 4; Chelsea, 3;
and Alexis, 2 months.

pleting a residency in otolaryngology at the University of Pennsylvania. He and his wife, Michelle,

WILLIAM PALM ER , JR ., '90,

completed a
residency at Duke University in

proudly announce the birth of a
son, Michaeljoseph, on April22,
1993. They have a daughter, Molly
Bess, born May 19, 1991.

was appointed chief resident of
physical medicine and rehabilitation at the University of Pittsburgh.

DAVID KATZ '88 ,

neurology and a fellowship in
neuro-ophthalmology at the
University of Michigan at Ann
Arbor. In july 1993, he joined a
group of neurologists in private
practice as a junior partner with
the subspecialty of neuro-ophthalmology.
an ophthalmologist, is a member of the
medical staff at ColumbiaGreene Medical Center in
Hudson, New York. Dr. Kraus
has joined the practice ofSanford
Ullman '38.

WAYN E Z I MMER ' 89 ,

Hopkins Hospital. Her husband
is an orthopaedic surgery resident, also atjohns Hopkins Hospital.

is com-

is a
third-year resident pursuing a
dual certification in internal
medicine and pediatrics at University and Children's Hospitals,
Cincinnati, Ohio.

JOSEPH BARROCAS , ' 91 ,

finished residency at The Children's
Hospital of Buffalo and joined the
Delaware Pediatric Group in
Buffalo.
HARR IET TE

F EIE R

' 90 ,

writes, "I
am completing a residency in
neurology at UCLA with an eye
toward an academic career in
neuroimaging. I married Lorain

DIANE KRAU S '88 ,

ANT H O NY L. CAPOCELLI, JR.,

completed a neurosurgery
fellowship at Long Island jewish
Memorial Hospital in june 1992.
He and his wife, Christy, announce the birth of a son, Bryce
Anthony, born September 14,
1992.

' 89 ,

B

a

ROHIT BA K S HI '91 ,

JONAT HAN

O ' BRIEN

' 90 ,

completed internal medicine
residency and started a gastroenterology fellowship at Albany
Medical Center in july 1993. He
has five children: Nathana, 5;
William, 4; Shoshana 3; Rebecca,
2; and Eli, born july 21.

Baeumler, R.N., daughter ofUB
med school alumnus George R.
Baeumler '59, on july 17, 1993
in Delaware Park - what a
catch! "

LI DIA PALCAN '90, announces
her marriage to james Wenz,
M.D., in Baltimore, Maryland,
on June 5, 1993. Lidia is currently a fellow in child and adolescent psychiatry at johns

0

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JOSE P H

M . ACCURSO

' 92 ,

recently reported for duty with
Naval Support Force Antarctica
in Port Hueneme, California.

c

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p

died last March in Cincinnati,
Ohio, of coronary heart disease.
Dr. Pulver was in the private
practice of pediatrics in White
Plains, ew York, for 20 years
before moving to Israel, where
he managed the health care of
children in the development town
of Hazor. He practiced pediatrics
with the Group Health Cooperative in Madison, Wisconsin after
returning to the U .5. A long-standing member of the Academy of
Pediatrics, he retired in 1989.
R OY J . THURN ' 52 , died on
September 12, 1993. His wife
writes, "Roy loved medicine and
finally retired at age 71 so we
could do some traveling, etc.,
that his commitment to medi-

cine postponed. He retired on
April 2 as medical director at
Bethesda Hospital, St. Paul, Minnesota, and on April 7 was diagnosed with inoperable small cell
cancer of the left lung. We attended his class reunions and were
looking forward to the next one."
D EAN

ALLE N

LES HER ~2 ,

of Newark, died oflungand heart
failure on August 12, 1993. Before retiring in 1992, he was a
researcher at the Ciba-Geigy
Corporation where he spearheaded the development of
Lopressor.

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��BUFFALO PHYSICIAN
STATE UNIVERSITY OF NEW YORK AT BUFFALO
3435 MAIN STREET
BUFFALO NEW YORK 14214

ADDRESS COR~ECTIOf'j R

The only
with thi~

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Society of the S
Since its fou
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review of claim
Calll-800-A
1-800-356-4056
mation and an &lt;

Our def€

2 Park Ave., Nev.
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90 Merrick Ave.
© 1993 Medical

Liabili~

�Non-Profit Org .
U.S. Postage

PAID
Buffalo, NY
Permit No. 311

' REQUESTED

S C I EI'; C E~

ri.\L L
~: L

ly liability coverage
is seal of approval.

jability Mutual Insurance
[LMIC) is the only professional
rer approved by the Medical
eState of New York.
:ounding in 1975, the physicianaanaged company has success~d more physicians than all
1le insurers combined.
lly, MLMIC has the largest
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nanagement department of
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we., East Meadow, NY 11554
bility Mutual insurance Company

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ADDRESS CORRECTION REQUESTED

The only liability coverage
with this seal of approval.
Medical Liability Mutual Insurance
Company (MLMIC) is the only professional
liability insurer approved by the Medical
Society of the State of ew York.
Since its founding in 1975, the physicianowned and managed company has successfully defended more physicians than all
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Additionally, MLMIC has the largest
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largest risk management department of
any New York State professional liability
insurer, and the state's only true peer
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Call1-800-ASK-MLMIC (metro) or
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Permit No. 31 1

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                    <text>State University of New York at Buffalo School of Medicine and Biomedical Sciences, Summer 1994

�BUFFALO PHYSIC I AN

Volume 28, Number 3
ASSOCIATE VICE
PRESIDENT FOR
UNIVERSITY
ADVANCEMENT

Dr Carole Smith Petro
DIRECTOR OF
PUBLICATIONS

Timothy j Conroy
EDITOR

Nanette Tramont, R.N.
ART DIRECTOR

Alan j. Kegler
ASSOCIATE ART D IRECTOR

Scott Fricker
PRODUCTION MANAGER

Ann Raszmann Brown
STATE UNIVERSITY OF
NEW YORK AT BUFFALO
SCHOOL OF MED ICINE
AND B IOMEDICAL
SCIENCES

Dr. john Naughton, Vice President
for Clinical Affairs, Dean
EDITORIAL BOARD

Dr. john A. Richert, Chairman
Dr. Martin Brecher
Dr. Harold Brody
Dr. Richard L. Collins
Dr. Alan J. Drinnan
Dr Timothy Gabryel
Dr. james Kanski
Dr. Charles Massaro
Ms. Melanie McNally
Dr. Charles Paganelli
Dr. Robert E. Reisman
Dr. Thomas Rosenthal
Dr. Stephen Spaulding
Dr Bradley T. Truax
TEACHING HOSPITALS AND
LIAISONS

The Buffalo General Hospital
Michael Shaw
Buffalo VA Medical Center
The Children's Hospital of Buffalo
Erie County Medical Center
Mercy Hospital
Millard Fillmore Hospitals
Frank Sava
Roswell Park Cancer Institute
Sisters of Charity Hospital
Dennis McCarthy
©The State University of New York
at Buffalo

Buffalo Physician is published
quarterly by the State Umversity of
New York at Buffalo School of
Medicine and Biomedical Sciences
and the Office of Publications. It is
sent, free of charge, to alumni, faculty,
students, residents and friends. The
staff reserves the right to edit all copy
and submissions accepted for
publication.
Address questions, comments and
submisstons to· Editor, Buffalo
Physician, State Universtty of New
York at Buffalo , University
Publications, l36 Crofts Hall, Buffalo,
New York 14260

Dear Alumni and Friends,

C

oncerns about the cost of health care in the United States also must include concerns
about the cost of educating medical students. The SUNY system has sought to
maintain tuitions that ensure students from all socioeconomic backgrounds access.
Despite this, the base annual tuition for New York State residents exceeds $8,000, and
most students require, seek and obtain major levels of financial assistance. UB's medical
school has addressed its commitment to alleviate students' financial pressures by encouragingscholarship support for meritorious and needy students. Thanks
to the generosity of many alumni. and friends, direct scholarship
support approximates $200,000 each year. But these funds provide
only 3 percent of the financial support required by UB's medical
students. For example, in the 1992-93 academic year, 88 percent of
UB's 555 medical students received some level of financial support
from scholarships, grants or loans. Total financial aid from all sources
approximated$ 7.5 million. In the 1993 graduating class, 25 students
had amassed accumulated debts of $50,000 or higher and one
amassed a debt that exceeded $80,000. The average debt for the class
neared $30,000.
This year's Class Reunion Campaign dedicated its donations to the Medical Alumni
Scholarship Fund, as will the next three campaigns. It is anticipated that over five years,
a principal of $500,000 will exist; its annual revenues will be used to enrich existing
scholarship support. The 1993 campaign provided a fine beginning to this goal with total
contributions of about $90,000. These funds not only recognize academic merit and
financial need, but reduce our students' debt burdens considerably.
The students, faculty and I are thankful for your continued interest in UB and in the
well-being of its medical student body.
~
Sincerely,
(.
J

0

~, ~
j ohn Naughton, M.D.
Vice President for Clinical Affairs
Dean, School of Medicine and Biomedical Sciences

Dear Fellow Alumni,

W

ith the beginning of a new academic year, your Medical Alumni Board looks
forward to providing experiences that enrich our medical students, house officers
and alumni. Recently, we welcomed the incoming residents and the freshman
medical class. During the year, we hope to impart to these physicians and
physicians-in-training a sense of camaraderie and a feeling of trust for one another that will
help the profession go forward. Activities such as the community physician program and
career presentations to freshman and sophomore students offer
guidance by established physicians in the difficult choice of career
planning. We plan another January reception for senior students, as
well as a Match Day celebration for seniors, along with out-of-town
receptions for alumni in other cities and at major medical meetings.
The 1994 Distinguished Alumnus Award will be presented in
September to Dr. Noel Rose. Dr. Rose's achievements in immunology
have been the cornerstone of many techniques and developments
utilized in daily clinical practice. His recognition is a source of pride
for all our alumni. The flagship event of our alumni year is Spring
Clinical Day and your board is busy putting together another informative event that will
also give us an opportunity to renew old friendships. Again on this day, Alumni
Achievement Awards will be presented.
As your new Alumni Association president, I look forward to this year and I ask for
your support in our endeavors. Please feel free to contact me with any of your suggestions.
Sincerely,
~

Send address changes to:

Buffalo
Physrcian, 146 CFS Addiuon, 3435
Main Street, Buffalo, New York l4214

&lt;

===-

Russell W. Bessette '76

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Research
Hospital News

II An Investment in the Future •

UB's medical scholarships benefit the students,
their benefactors and the profession.

m

Going Beyond the Curriculum e

Today's medical students focus their free time on
research and community service.

E!J ASpoonful of Humor

Using spare time wisely.
Page 14.

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Alumni

EZJ Medical School

IJ Classnotes

*

~n t~e ~ouer:

ffiilnren ~anes
ann t~e first
~anes ~c~olar.

~arnara ~earne~.
Mat'h Day '94: It was a very gaad year! Page 38.

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Buffalo General Hospital to join in
national stroke research study
he Buffalo General Hospital's neurology department is participating in nationwide research comparing the effectiveness of aspirin
with the anticoagulant Coumadin
in preventing strokes among patients who have already suffered them.
"The data should give doctors clearer
scientific guidance about which treatment will best protect patients from a
second stroke," said Patrick Pullicino,
M.D., the study's principal investigator.
The study will last two years and will
enroll 2,000 patients in more than 30
centers throughout the United States.
The Buffalo General Hospital study
team, which includes collaborating investigator Frederick Munschauer, M.D.,
and study coordinator Margaret Hens ,
R.N., Buffalo General stroke projects
coordinator, hopes to enroll about 60
patients. Patients eligible for the study
must have had a stroke within 30 days
and be between the ages of 30 and 85.
Patients with cerebral hemorrhage, or
who are unable to take Coumadin, are
not eligible to participate.
For further information, contact
Pullicino at 845-3703.
+

New anesthesia regime reduces
high-rtsk cardiac complications
hanging the type and method of
administering anesthesia and pain
medication to high-risk surgery
patients can dramatically reduce
the risk of postoperative cardiac
abnormalities and possibly lessen
the chance of a heart attack, University
at Buffalo researchers have found .
A team of anesthesiologists led by
Oscar de Leon-Casasola, M.D., UB asB

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The study will compare the effectiveness of
aspirin with Coumadin to prevent second strokes.
sistant professor of anesthesiology, followed the surgery and early recovery of
198 patients admitted during one year
to Roswell Park Cancer Institute for
upper abdominal cancer surgery.
One group of 88 patients received
standard general anesthesia during surgery and morphine for pain after surgery, self-administered through an intravenous line.
Another group of 110 patients received combined anesthesia therapy
using bupivacaine and morphine via
epidural. After the operation, the same
two drugs, adjusted to pain control,
continued to be administered by epidural.
All patients had an electrocardiogram
every 12 hours for three days following
surgery to detect cardiac abnormalities.
Results showed that patients in the
epidural group had 51 percent fewer
incidents of tachycardia (15 versus 58) ,
12 percent fewer episodes of ischemia
(five versus 15) and suffered no heart
attacks. Three heart attacks were reh

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ported in the general group; none was
fatal.
De Leon-Casasola said about 40 percent ofhigh-risk patients suffer ischemia
after surgery; 8 to 20 percent suffer
heart attacks.
When surgeons at Roswell reported a
significant drop in heart attacks following major cancer surgeries, a team of
anesthesiologists began to investigate why.
"We had been using combination
therapy for about five years ," de LeonCasasola said, "and there was much data
suggesting that patients receiving a combination of anesthesia agents via epidural had better outcomes. So we decided
to take a look at that issue."
Researchers theorize that the epidural anesthesia dilates the coronary blood
vessels to help prevent ischemia and the
morphine better controls pain to prevent nervous system stimulation. +
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BAKER

Smokers at rtsk for pertodontal
disease,separate UB studies find
making may be a key risk factor in
periodontal disease , University at
Buffalo researchers have concluded.
Results of separate studies by Joseph Zambon, D.D.S. , Ph.D ., and
Robert ]. Genco , D.D .S., Ph.D .,
found that smokers experienced less
attachment of tooth to bone and more
bone loss around teeth than non-smokers.
In a study of 1,426 adults ages 25 to
74, Zambon found that the loss offiber
attachment of tooth to bone was three
times greater among current smokers
- 12.03 percent vs. 4.28 percent compared to non-smokers.
Zambon, professor of periodontics, also
reported a 120 percent increased risk of
infection with bacteria that cause periodontal disease for every step in levels
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from light to heavy smoking. He reported
current smokers had higher levels of Actinomyces actinomy-cetemcomitans,
Bacteriodes forsythus and Porphyromonas
gingival is- all of which cause periodontal disease- than non-smokers.
Genco, chair of oral biology, studied
1,361 adults ages 25 to 74. He found
that smoking increased bone loss around
teeth, a risk that increased from 3.34 to
7.35 times from light to heavy smokers.
Researchers included Sara Grossi,
D.D.S., senior research scientist; E. E.
Machtei, D.M.D., visiting associate professor; Alex W. Ho, research support
specialist; Robert Dunford, senior scientific programmer; and Ernest
Hausmann, D.M.D., Ph.D., all with the
+
department of oral biology.
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"We are making new versions of human hemoglobin by growing the pro- _
tein in bacteria and doing site-directed
mutagenesis," he explained. "We can
change any amino acid in a protein into
any other amino acid we choose. In this
way, we hope ultimately to design a
molecule that will function optimally as
a blood substitute."
+

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The grant will allow UB researchers to continue
developing a synthetic form of hemoglobin.

that will function outside a red cell,
explained that when hemoglobin is removed from red cells it binds oxygen so
tightly "a person could have a generous
supply of oxygen and still suffocate because the oxygen wouldn't be released
to the tissues."
Noble's approach involves manipulating the amino acid sequence of the
hemoglobin molecule and observing
how its structure affects its function .
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multi-center study in which UB
researchers from The Children's
Hospital of Buffalo participated,
has found that high-dose intravenous respiratory syncytial virus
immune globulin is a safe and effective means to reduce the severity of
the disease in children.
The three-year study involved 249 highrisk children in Buffalo, Rochester, Boston, Washington, D.C. and Denver.
Debra A. Tristram, M.D., and Robert
C. Welliver, M.D., of the center for
infectious diseases at Children's, were
supporting investigators for the study,
published late last year in The New England journal of Medicine.
Tristram said between 35 and 40 children have been treated with RSV immune globulin at Children's. "Overall,
the treatments had good benefits for the
children in the study. They had less
respiratory ailments and were less likely
to acquire severe RSV," Tristram said.
The new treatment compound uses
antibodies extracted from the blood of
volunteers such as pediatric nurses who
have been exposed to RSV and have
high RSV antibody levels.
"Children were hospitalized less often and required less intensive care treatment than· children without the infusions," Welliver added.
+

UB receives $1.1 million grant to
continue hemoglobin research

B

LOIS

New treatment compound found
eiTective in reducing RSV severity

PINA

esearchers at UB have received a
$1.1 million grant to continue
developing a synthetic form of
hemoglobin, joining researchers
from five other institutions participating in the $6 million, fiveyear study funded by theN ational Heart,
Lung and Blood Institution.
Robert Noble, Ph.D., professor of
medicine and chief of the laboratory of
protein chemistry at the Buffalo VA
Medical Center, is principal investigator on the UB project.
The new funding will allow the team
to continue research begun with a $1.3
million grant in 1988.
"We are trying to obtain the fundamental knowledge that will enable us to
design a molecule that will serve better
as a blood substitute than normal hemoglobin," Noble said.
Noble, whose team is concentrating
on developing a form of hemoglobin

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�"Chemo Coach"program begins
in Western New York hospitals

RPCI opens area'sfirst regional
Brain Tumor Treatment Center

he American Cancer Society's
"Chemo Coach" program, which
matches chemotherapy patients
with one-year post-chemo patients
for support, has begun in Western
New York hospitals.
The program, developed by ACS's Erie
County Unit, recently won the society's
award for being the most innovative
program in the nation.
"The program is based on
the belief that someone who
has 'been there' will encourage and empower the patient.
Healing and wellness is promoted by motivation, encouragement , caring and support," said Hillary Ruchlin,
director of patient services for
the Erie County Unit of the
ACS.
All coaches are trained not
to dispense any medical information or advice and have
completed volunteer training.
The program, begun last August after nearly two and a half
years of development , has
served 275 patients to date. It
will be introduced nationwide
this year.
"We match patients and
coaches according to age and
type and location of cancer. The
coaches then meet the needs of the patients by providing information and support and showing them that there is life
after chemo," Ruchlin added.
Seventy-five chemo coaches have been
trained and are available through the
Erie County ACS office. The program is
available through patient or physician
referral.
For more information, call689-6981. +

n recognition of the somewhat
higher incidence of brain tumors
in Western New York than in the
nation, Roswell Park Cancer Institute has opened a Brain Tumor
Treatment Center- the area's first
major regional referral center for the
multidisciplinary management of patients with brain tumors.

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national Chemo Coach program was
developed by the ACS' s Erie County Unit.
"The Brain Tumor Treatment Center
will provide for comprehensive treatment of all types of brain tumors in
adults at one centralized location in
Western New York," said Kyu H. Shin,
M.D., professor and chairman of radiation oncology at UB and chairman of
the department of radiation medicine at
Roswell. Shin is one of the founders of
the new center.

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The center - headed by neurooncologist Laszlo Mechtler, M.D. , clinical assistant instructor and assistant
professor of neurology- is a collaborative effort between Roswell, The Buffalo
General Hospital, The Children's Hospital of Buffalo, Millard Fillmore Health
System and Erie County Medical Center.
"By combining these resources and
expertise, the scope of care provided
goes far beyond what is available in
community hospitals and at
other regional teaching centers," noted Shin.
The center provides diagnostic, treatment and surgical
services in multi-specialty areas.
In neuro-oncology, under the
direction of Mechtler, neuroimaging, chemotherapy (including intra-arterial and intrathecal),
neuro-oncological care and neurooncologic pain management are
offered.
In neurology and neuroimmunology, under the direction of Steven
Greenberg, M.D., assistant professor of neurology, microbiology and
immunology and chairman of the department of neurology at Roswell, services offered include neurological care,
molecular diagnosis and a tumor tissue repository.
In neurosurgery, under the direction of Walter Grand, M.D., clinical
professor of neurosurgery, and Charles
R. West, associate professor of neurosurgery and chairman of neurosurgery
at Roswell, services offered include stereotactic biopsy and surgery, both invasive and superselective neuroradiology
and photodynamic therapy.
In radiation medicine, under the direction of Shin, services offered include
radiosurgery, interstitial brachytherapy
of brain tumors, photodynamic therapy,

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�intracavitary radiation therapy and cerebral spinal axis radiation.
Patients may be referred to the Brain
Tumor Treatment Center by calling the
Patient Referral Office at 1-800ROSWELL.
+

must be screened and cleared by their
physicians," Ward noted.
Since the startup of Western New
York's only lithotripsy service in December 1986, urologists have performed
nearly 7,000 non-invasive treatments
on kidney stone patients at The Buffalo
+
General Hospital.

Memorial Pediatrics provides wellchild care, sick care, immunizations,
sports and school physicals, lead testing, birth control, teenage counseling,
supportive services for physical and
sexual abuse and 24-hour emergency
coverage.
+

iagara Falls Memorial Medical
Center has opened a pediatric
primary care center.
Formerly known as the "Kid's
Clinic," Memorial Pediatrics, at
501 TenthStreetinNiagaraFalls,
has evolved from a part-time clinic to a
full-time pediatric service to improve
the quality and continuity of care for
families living in the Niagara Falls area.
"Our goal is to serve the people in this
community who don't currently have
physicians," saidjack Coyne, M.D., the
program's medical director. "We're here
to offer comprehensive, quality health
care for families in a pleasant, sensitive
atmosphere."

appointed president of the medicaVdental staff at Buffalo Columbus Hospital.
A native of Cuba, Perez-Bode
earned his doctorate of dental
surgery at the University of Havana's
School of Dentistry. After coming to the
United States as a refugee in 1968, he
received his New York State dental degree from the University at Buffalo
School of Dentistry.
He has been on the staff of Columbus
Hospital since 1989. A member of the
Cuban Dental Association in Exile, he
served as vice president of the medicaV
dental staff at Columbus before his appointment as president.
+

Buffalo General introduces new
"waterless"lithotripsy technology Niagara Falls Memorial Medical Perez-Bode named president of
Columbus Hospital medical staff
he Buffalo General Hospital, which Center opens Memorial Pediatrics
pioneered the use of extra-corpoene Perez-Bode, D.D.S. , has been
real shock wave lithotripsy in
Western ew York, has added
waterless technology to the water
bath lithrotripsy it introduced
more than seven years ago.
The move is expected to reduce a
patient's length of stay to less than one
day in most cases and minimize the pain
associated with the procedure.
During a "dry" lithotripsy procedure,
a gel-like substance is applied to the
patient's back, which is then positioned
against a small water-filled cushion.
"Because there is less pain associated
with the new technology, the need for
general anesthesia is eliminated in most
cases. An intravenous sedation is used
instead, allowing the patient to return
home the same day," said Phyllis Ward,
nurse coordinator of lithotripsy services
at BGH.
"Since the patient is no longer immersed in water, the visualization of the
kidney stone by X-ray equipment is
dramatically improved and the length
of time to localize the stone also is
decreased," Ward added.
Ward also said that a patient's sizean important consideration in water
bath lithotripsy - is no longer an issue.
Even with the new technology, she
noted, some of the previous eligibility
criteria still apply. "Pregnant women
still are not candidates for the procedure, and people with cardiac problems
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Memorial Pediatrics will provide full-time pediatric services to families in the Niagara Falls area.
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�Investing in the

U:U'8 med:ieft;I 8ehoift;:r8h:ip8 p8;y
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In the 0 ffices of the University at Buffalo
Foundation, there is a list. On the list are a couple
of dozen names. And on those names hangs the
educational fate of a great many future physicians.

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�It's the listofpeople
who have made a commitment to the
next generation of healers: they've
endowed scholarships for students
learning their craft at the UB School
of Medicine and Biomedical Sciences.
Some are alumni of the medical
school, giving back a token of what
their education has made it possible
for them to earn. Some are former
faculty members who've seen firsthand the bright, committed young
people who continue to enter the
profession. Some are just interested
citizens who know that, despite UB's
relatively reasonable tuition costs,
some students would not be able to
make their dreams happen without
significant financial aid.
And some who have endowed these
scholarships, it must be said, are no
longer with us.
It's an irony of charitable giving
that so often a gift is made in the form
of a bequest - a provision in one's
will. Such support, of course, can be
vitally important in building up the
endowment funds that are the basis
for the medical school's scholarship
programs.
But other donors have found that
there's nothing so satisfying as actually watching your money go to work,
seeing the good that you can do in
individual lives.
Ask Thelma Sanes.
A handful of years ago, Sanes established the Harold Sanes and
Thelma Sanes Medical Scholarship
with a major donation to the school.
The scholarship- named for Thelma
and her late brother Harold- was in
recognition and memory of their late
brother Samuel, professor of pathology at the medical school for many
years and head of pathology at the
former Meyer Memorial Hospital
(now Erie County Medical Center).

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�Harold Sanes

had
passed away in 1986. ButThelmaSanes
can watch with pride the results of
their living gift to the future of the
medical profession their brother loved
so much and gave so much to .
This year, the first of the "Sanes
Scholars" graduated from the medical
school; at any one time, four such
students receive aid from the Sanes

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grant. The scholarships, which nearly
cover the school's $8 ,450 annual tuition, are renewable for each year of a
student's education.
"I had written up how I wanted the
scholarships to be paid," Sanes said.
"They're given every year, but the students who get them, get them for four
years. I felt that anybody who met the
criteria of the scholarship is someone

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who is in need , and I didn't want to
dump them after freshman year. "
The scholars have a genuine affection for their benefactress. "Most of
the winners have written me letters of
appreciation," Sanes said. "Occasionally I even get a Christmas card from
one of them. They're very nice people. "
There's an annual luncheon as well,
she said, at which donors and scholar-

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�ship winners can meet.
Sanes said she has made provision
in her will, as well, for an additional
donation- "to cover inflation."
"I figured, there's going to be
enough left. Part of it should go where
it will do some good."
That it has. The first Sanes Scholar,
Barbara P. Kearney, graduated on May
15, having had the scholarship for all
four years of her medical education.
"It was wonderful," Kearney said
of the day she learned she had won the
scholarship. By invitation, she had
written a brief essay about her accomplishments and stated the case for her
financial needs. The good news came
in a phone call from Thomas ] .
Guttuso, M.D., assistant dean for admissions.
Between then and graduation, of
course, were the strenuous four years
that begin to turn scholars into physicians. But through all the work that
those years entailed, Kearney said,
she knew that the endowed scholarship - in her case, $5,500 annually
-was there to help make it possible.
A lot of her fellow students, she
pointed out, will leave UB medical
school with crushing debt burdens.
"I still have some loans that I've
taken out," she said. "I had to buy a
car, and there are the books. But it's
only about half of what I would have
had to take out."
What that means, she said, is flexibility in choosing a field of practice.
(New residents who are tens of thousands of dollars in debt can feel pushed
into a high-paying specialization.)
Kearney began her residency in pathology with the Graduate Medical
Dental Education Consortium of Buffalo onjune 12.
"A lot of my friends have parents
and relatives who've helped them
along through school," she said. "But
that's not possible for everyone.

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"Any scholarship or any kind of
grant that can be made available, I
strongly encourage (potential donors)
to do that."
Even gifts of smaller scope can make
a significant difference in the scholarship aid the school can distribute, said
Guttuso.
By pooling smaller gifts, the medical school can assemble scholarships
for those in need. Right now, he said,
about 35 students are benefiting from
scholarships that total around $60,000
annually. "It's our hope," Guttuso said,
"that we can build a scholarship fund
that will enable us to help close to half
the class each year." Each class of the
medical school has 135 students.
Guttuso said students are considered for aid based both on their academic promise and on their financial
need. Twenty "scholar incentive
awards" are given to applicants solely
on their academic promise, he said"we're trying to attract the most intelligent students to come to our institution." But for all other scholarships,
need is a factor in the decision.
Each spring, Guttuso said,
his five-person scholarship
committee sits down and sifts
through the applicants for aid.
It's a wrenching process.
"It's kind of tough sometimes, when
you get down to 50 or 45 students," he
said. "To eliminate some is hard, because they all really need it. That's
why we're hoping that we can expand
the program to help a greater proportion of the students."
Except for the minimal Regents
Scholarships, New York State provides
no money for scholarships, notedjohn
A. Richert, Ed.D. , associate dean for
alumni affairs at the medical school.
"Monies are few and far between," he
said.
One major initiative to expand
scholarship assistance is the establish-

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ASSISTANT DEAN
FOR ADMISSIONS

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�ment of Medical Alumni Scholarships,
to be funded by those who know best
how expensive it can be to go through
medical school - the alumni themselves.
Dr. Donald P. Copley, a cardiologist who was president of the Medical
Alumni Association last year when
this plan took shape, explains.

"Last vear

when we
began organizing for the reunion class
spring session, I brought this idea up
to all the (class reunion) chairmen at
the same time," he said. "The question I posed was, if we pull together
and all of the classes got together
quite a few thousand dollars, and the
(Medical) Alumni Association promised to retain an identity for everybody involved- that is, identify particular students and maybe associate
them with particular classes and link
up person-to-person - would the
chairmen and their constituencies be
interested?
"It turned out there was a pretty
universal enthusiasm for the idea."
So for the '93 class reunions, again
this year and for the next three years,
alumni class gifts to the school will be
funneled into what promises to become a major scholarship endowment.
(The five-year cycle was established
to give members of every class the
opportunity to contribute. Some individual classes, notably the Classes of
1957 and 1973, already have established scholarship funds; but this is
the first time all the classes together
have the opportunity to contribute to
a combined fund.)
Class gifts to the school have averaged around $100,000 each year,
Copley said, and planners of the Medi-

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cal Alumni Scholarships hope to ex- books," says Claudia Jaramillo, anpand on those figures . "We're shoot- other alumni scholarship recipient.
ing for $1 million," he said, "but at "That's usually what it comes to for a
this point it's awfully hard to tell year (of books).
(whether that goal is attainable). If we
"The budget usually fora (UB) medigot to $500,000 or $600,000, we'd cal student is about $20,000 a year,
still be quite happy about it."
especially if you're not living at home.
There was some controversy, he But still, anything you can get, espenoted, over whether recipients of the cially $1,000, is definitely helpful."
scholarships should be chosen on acaFellow recipient] eannie Kao notes
demic merit or simply on need. "Half that her student loan was reduced by
the people I talked to thought that the amount of the alumni scholarneed should be a major consideration, ship, "and to have that be $1,000 less
so that people who had no resources is really nice." With interest, of course,
or very little resources would be the loan repayment can be much greater
ones who were offered the scholar- than the principal borrowed, so a
ships," Copley said. "An equal num- $4,000 reduction (the scholarships
ber of my constituency thought that are for all four years) is a major benefit
merit should be the only criterion."
down the road.
The outcome: a time-honored com"As a medical student," says scholpromise, in which academic merit arship recipient Frank M. Lee, "you
will be the primary focus in half the really don't have the time to take on a
scholarships, financial need the de- job except in the summertime. The
termining factor in the other half.
scholarship does cover my books at
"The idea," Copley said, "is to carry least, which is nice.
each of these individuals through four
"Since UB is not really that expenyears of school." He noted that john sive to start off with, you do come out
P. aughton, M.D., dean of the medi- with a debt, it's not in the hundreds of
cal school, has supported the alumni thousands but still it's something you
initiative with some discretionary have to think about. The scholarship
money he has available. "Dean makes more of a difference in a school
Naughton was particularly enthusi- like ours," because it represents a
astic and helpful," Copley said.
greater portion of the cost of medical
Already the Medical Alumni Schol- education.
For those with the means to make
arships are providing significant support to first-year students. "It's a great a major gift of scholarship money, UB
feeling to pick up that $500 check at offers two possibilities: an annual
the start of each semester," says one scholarship or an endowed scholarsuch student,]ason M. Andrus. "It's a ship, both of which can be established
couple months' rent. It's a terrific through the Office of University Defeeling to think that your school thinks velopment.
An annual scholarship is a gift of
that you're unique and they're going
out of their way to assist you like about $8,000 or more for one year, or
that. "
annually for several years, to support
"Definitely it helps, especially with a student's educational expenses for

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�those years.
By contrast, an endowed scholarship is a gift of at least $150,000 that
is then permanently invested and the
income used as scholarship assistance.
It's a gift that continues beyond the
donor's lifetime.
Michael E. Benzin, associate director of special, annual and regional giving for the University at Buffalo Foundation, noted that the foundation has
experience in handling gifts of all sizes.
The endowment managed by the foundation for the university is now $40
million. (Donations earmarked for the
medical school are managed by the

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foundation, but the school itself decides
who is to receive the scholarship money
they generate.)
Unrestricted gifts are encouraged,
because they afford the most flexibility in meeting students' scholarship
needs. But major donors , Benzin said,
can structure their gifts in any number of ways. For example, if a surgeon
wants to endow a scholarship that
would go only to students who aspire
to surgery, that's entirely possible. Or,
he said, "if (the donor) worked his
way through medical school and
would like to assist a student who's in
that situation, you can do that, too ."

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Benzin said endowment money is
invested conservatively and that a part
of the interest is channeled back into
the principal so that its "buying
power" isn't eroded by inflation.
And he reminded potential donors
about the james Platt White Society,
founded in 1986 to honor donors to
the medical school of$1,000 or more.
Named after a founder of the school,
the society has about 200 members.
As Barbara Kearney , the new pathology resident, said of her Sanes
scholarship: "There's just so many
people out there who could benefit
from something like this. "
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��o
ree time is a scarce commodity for medical students. But one Saturday morning this spring,
Amy Ferry was spending some of hers with a homeless man in Buffalo's City Mission. The pain in his
feet and knees had gotten so bad he was having trouble walking. And he was feeling run down and
depressed.
"Any drugs?" asked Ferry, who was completing her fourth year at the UB School of Medicine and
Biomedical Sciences. Not any mor_e, the man said, but he still drank.
"Do you see your drinking as a problem?" Ferry asked.
"I see me as a problem, period," the man replied.
After the man had been referred for further treatment, Ferry reflected on why she was devoting this
morning to Project Hope, the weekly City Mission clinic run by student volunteers from the UB
medical school. "Doctors are expected to be involved in the community," she said simply
It's the same reason she spent last summer on Capitol Hill, lobbying over tobacco and mammographies.
"It's part of learning to be a doctor," she added.
Ferry is among the large number of medical students who take it upon themselves to extend their
educations beyond the curriculum requirements. Some work in clinics with underserved populations.
Some teach health lessons to school children. Others spend long hours in the laboratory helping to
carry out research.
They do it to varying degrees and for a variety of reasons: a sense of social responsibility, intellectual
curiosity, clinical experience, diversion, career advancement or just the challenge.
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�~

~ese are talented kids in many
respects, and they do a lot of things, "
said Richard] ones, Ph.D., medical school
registrar .
No one keeps tabs on exactly how
many students take part in activities
that aren't required but are professionally relevant. Thomas Flanagan, Ph.D .,
chairman of the Student Research Committee, said that at last count, several
years ago , more than 300 UB medical
students were involved in research. Recent projects include investigations into
DNA, the epidemiology of neuroblastoma in New York State, alcohol-related
injuries in children and adolescents and
the exposure of medical students to
blood and body fluids .
And student leaders estimate that
half to three-quarters of their classmates
get involved in some type of voluntary
service activity, from medical clubs to
clinic work. Among the larger student
initiatives are Project Hope and a pair of
programs that put medical students into
the schools to teach children about AIDS
and healthy diet.
"Most students will get involved even
at a peripheral level in something," said
Melanie McNally, 1993-94 president of
Polity, the medical school's student government council. Those who do get involved may spend less than an hour a
week on outside activities. Research,
however, can easily take several hours a
week. And some students find themselves with the equivalent of a part-time
job.
"I think a lot of it depends on how
you handle your own stresses," said
Eileen Killackey, a Project Hope volunteer who is going into her third year. "I
think it depends on what you're most
concerned about doing while you're in
medical school. .. . In a way, it's something to keep you going. It gets you out
of the classroom and in touch with what
you're actually going to be doing at the
end of four years. It's like light at the end
of the tunnel. "
But getting involved at more than a
peripheral level can force students to
make tough choices.
"Your grades can reflect it," said

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ence on match day. "If you're visible , it
does go down in your dean's letter," said
McNally. "Right now, that's the only
non-personal benefit you get out of it. "
But it's the personal benefits that
often matter most. It's not uncommon
for students to describe their volunteer
work in terms of social and professional
responsibility. Many see the work as a
way of helping others while preparing
themselves to become better physicians.
"It's definitely a two-way street," said
Sarah Ballow, a Project Hope volunteer
going into her third year.
"Most of the people who get involved
in these activities have a desire to do
something," said McNally. "That's why
they got into medical school in the first
place - because they wanted to do
something for their community."
Flanagan said that while many student researchers take on their projects
with an eye toward honors and residencies, a good number do it out of simple
intellectual curiosity. "Some have a specific disease interest that they want to
pursue," he said. "Some kids have had
no research experience and just want to
see what it is. "
The research projects cover a broad
spectrum, from laboratory "bench" research, to clinical investigations and
even health policy work.
Every year, the medical school supports about 20 students in its 10-week
Summer Research Fellowship program.
Applicants must submit detailed proposals, and only about half are accepted,
said Flanagan.
But in most cases, student researchers get started simply by talking to a
professor and signing on to projects
already under way. Many do it in the
summer after their first or second year,
when there's a little more time. And if
there's a grant supporting the project
and some money to spare, there may be
a stipend in it for the student.
Tom Guttuso,jr. , said that when he
started medical school he didn't plan to
become a researcher, but he became
engrossed in the laboratory after his
first year and the experience has "completely changed" his medical education.
Guttuso received a summer research
fellowship in 1992 to work with physi-

Michael Landi, M.D., a Class of 1994
member who conducted several research
projects. "I know my first-year and second-year grades were probably a little
bit lower because of the time I put into
research ."
McNally said her student government work has forced her to manage
time better - to a degree. "You make
the time, you really do ," she said. "Then
you go and beg your professors to have
mercy. "
Dennis A. Nadler, M.D., associate
dean for academic and curricular affairs, said UB encourages students to go
beyond the classroom. "Our university,"
he said, "stands on a three-legged stool
-academics, research and service."
Official encouragement, however, has
been somewhat uneven. Some students
who participate in research can garner
extra points toward Latin graduation
honors . But no points are awarded for
those who participate in community or
university service, such as volunteering
at a clinic or serving as a student representative on a university committee.
That may be changing. Nadler recommended last year that service activities be rewarded with graduation honors, and as early as this fall- depending
on the outcome of a faculty council
meeting in late May- a revised honors
system could take effect. Under it, new
categories of diploma honors would be
created for research and volunteer service. Latin honors would revert to the
traditional system, in which they are
bestowed strictly for academic achievement.
"We really feel that we have a commitment to serve the community as a
medical school, and that extends all the
way down to the students," said Nadler.
"What we haven't had in the past was an
adequate way of rewarding the students."
Even without honors, extracurricular work can mean career benefits.
"So many residency programs are
interested in whether students have done
any research," said Flanagan, a microbiology professor who oversees the medical school's Research Forum and Summer Research Fellowship programs.
In some cases, community and university service could also make a differ-

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�ology professor Susan Udin, Ph.D., on
visual plasticity in frogs. "We were working on basically trying to get the visual
nervous system to reorganize and heal
after it's been damaged and I just kind of
fell in love with it.
"I ended up really digging it so much
that I did it through the second year of
medical school - before classes, after
classes, during some of the more boring
classes."
Then he took off the 1993-94 academic year, which
would have been his
third, for full-time
study of the hormone
melatonin with a
$23,000 grant from the
Howard Hughes Medical Institute.
Guttuso was unable
to prove an effect on
frog visual systems, so
he switched gears to
pursue his theory that
melatonin could prevent or slow the development of Parkinson's
Disease.
"It's been a lot of
work to get this model
up and running," he
said. But, he added, the
results could be much
more clinically relevant than his original
line of inquiry. His results, unfortunately,
have been "inconclusive," but because of a
design flaw in the experiment rather than
his theory. Guttuso
"hopes to do it again
this summer."
Ultimately, Guttuso
said he would like to make research part
of his career, mixing it with clinical
practice, possibly in neurology.
"It's put the thought into my head
that I'm going to do something that I
never expected to do when I entered
medical school," he said.
"Once a student gets involved in research, they very frequently will continue," said Flanagan. "They will do it in

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gery residency at Mercy Hospital in Buffalo this year, has been involved in several research projects, including a study
into the exposure of medical students to
patient blood and body fluids. He said he
found that about 30 percent ofUB's class
of 1993 was exposed through needle
sticks, mucous membrane splashes and
other means during third-year rotations.
"That's pretty consistent with the class
of 1994, too," he added.
The study began when Landi read a
letter in the medical
school newspaper
from a former student
who had contracted
hepatitis during her
rotations. A snafu left
the woman unaware
for several weeks that
she had tested positive
for hepatitis, prompting Landi to look into
student exposure rates
and the policies for
dealing with such
cases.
"It was just because
I was kind of offended," he said.
Landi, who is submitting the UB study for
publication, is still reviewing results from a
larger subsequent survey he conducted with
another UB student of
exposure rates at seven
medical schools across
New York State. He
also helped develop a
comprehensive policy
for UB's consortium of
teaching hospitals to
handle student exposure cases. Previously,
there was no consortium-wide policy.
Landi never calculated how much time
he put into his research, but he remembers spending a lot of evenings and weekends with it. "I wouldsayit'sagood parttime job," he said. "It gets kind of labor
intensive when paper writing comes
around. "
Students who take on significant extracurricular responsibilities say it forces

their free time during the school year.
They don't have a lot of time, but they
make time."
Under the graduation honors policy
in effect in recent years, students could
earn Latin honors points if their work
was accepted for presentation at the
annual Research Forum, and their supervisor approved.
"A lot of the work is very good and
leads to publication," Flanagan added.
The medical school encourages re-

search, partly to make students aware
of the career possibilities, but also to
turn out more rounded clinical physicians. "It's one thing to read the outcome of research and another thing to
actually conduct it, to confront the solving of problems, to be frustrated by
things that don't come out the way you
expect them to," Flanagan said.
Landi, who is beginning a neurosur-

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�them to set prionttes. "Some people
manage to pull off the top grades even
with this, but most of us are in the B
range," said McNally, the Polity leader.

Many students describe their extracurricular activities as a good way to
experience a broader world that will be
relevant to their professional futures.
McNally said that in being responsible for the $88,000 in student activity
funds distributed by Polity, she's learned
something about accounting. "I have
become very interested in the administrative side of medicine," she added.
"I've found that I'm very good at this,
and I'm hoping to make it part of my
career."
At Project Hope, students deal with

unteers how to take histories and talk
with the homeless patients.
"I've always been interested in serving underserved populations ," said
Ballow, who worked in a soup kitchen
during her high school years in Connecticut. This summer, she will conduct
US-sponsored research at a Navaho reservation in Arizona. She has also managed to keep up a relationship with her
boyfriend, who lives four hours away in
Pittsburgh. ''I'm a very organized person," she said with a smile.
Project Hope began several years ago
as an outgrowth of a City
Mission clinic run by the
School of Nursing. "We just
wanted to do more outside
the classroom, to use what
we were learning," said Joe
Kay, M.D., who graduated
this year to begin a residency
in internal medicine and pediatrics.
Kay said he enjoyed his
time with the clinic. "You're
doing it because you want to,
rather than being evaluated
all the time," he said. "It's a
different atmosphere than the
hospital. It gives you an idea
of the problems with the
health care system, too ."
Many students involved
with Project Hope agree that
the experience has affected
them. "I always find that
talking to the patient is a
very humbling experience,"
said Killackey. "Medically
speaking right now, I don't
know how best to help
people because I don't have
the clinical skills. But with
situations they might not see on hospi- these community projects, you find out
that your just being attentive and listental wards.
"If someone comes in with a simple ing to these men and women can make
foot fungus, you tell them to clean their a big difference." There are limits, howfoot and change their socks," said Cook. ever, to how much students can take on.
"Then you find out they only have Ferry, who will begin her residency this
one pair of socks."
year in obstetrics and gynecology, served
About 60 students are involved in two years as regional student co-coordiProject Hope, according to Ballow, who nator for the American Medical Women's
helps administer the program. Each of Association. "They wanted me to run
those students spends at least one Satur- for national co-coordinator," she reday morning at the clinic. Ballow is called. "I said not while I'm an internthere once a month, showing new vol- no way, no how."
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think there is definitely a
trade-off," said Stephen Cook, who in
his first two years has been involved in
Project Hope, a pair of Buffalo pediatric
clinics and the Primary Care Club. Recently, he also initiated an undergraduate
clinic for Niagara University students interested in medicine.
"I enjoy doing these
things," he said. "It's time I
could spend learning gross
anatomy or biochemistry, but
that's the type of person I am.
I'm a more humanistic person. I like dealing with
people."
Noah Sabin, a 30-yearold attorney who just finished his first year at UB
medical school, has been adding to his list of responsibilities. During his first year,
Sabin was elected vice president of the American Medical StudentAssociation chapter. He also signed on to a
national AMSA task force on
tort reform, and will work on
environmental health issues
with Rep. David Obey, DWisconsin, in Washington
this summer as an AMSA fellow. In addition, Sabin said
he tries making time to exercise and keep up on his nonmedical reading and current
affairs.
He described time management as
something that's subject to amendment
as exam results come back.
"I sort of have a sense from looking
back at law school of how much those
grades really meant in the long run," he
added. "They meant a lot if you're looking for a certain amount of prestige in a
certain field . ... (But) the people defining what's most prestigious have spent
their entire lives in those environments,
and they don't really know what else is
out there."

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edical school makes a lot of
demands, but it doesn't demand that
students volunteer their time for
research or public service. Yet many
do . Here are some of the things
they're involved with:
RESEARCH

"The student research at UB takes
a number of faces, " said Luther
Robinson , M.D. , assistant dean of
student affairs.
Student work ranges from basic
biology to the genetic basis of cancer. "The spectrum of research in
medicine contributes to the intellectual climate in medical school,"
Robinson added.
Students most frequently get involved by approaching a professor
already carrying out a research
project. Some departments have
grants to sponsor research opportunities, as well.
And each year the university supports about 20 students in its Summer Research Fellowship program.
Applicants must submit detailed
proposals to a faculty committee for
the full-time, IO-week program.
In addition, student researchers
can apply to present their work at
the annual Research Forum. At the
last forum, in December, more than
70 students made presentations.
"This is not the science fair ,"
said Thomas Flanagan, Ph.D. , chairman of the Student Research Committee. "This is real research. "
PROJECT HOPE

About 60 students are involved
in this Buffalo City Mission clinic,

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American Medical Student Association, the AIDS-prevention program
began at UB last year. Since then it's
reached nearly 10,000 students in
Buffalo-area junior high and high
schools. About 55 first- and second-year medical students take part.
"We talk about the biological
aspects of AIDS- transmission and
prevention," said Beth MacDonald,
who just finished her second year
and is STATS coordinator.
"The questions are usually very
specific and very explicit," she
added. "The questions show that
the kids obviously need to learn."

which is an expansion of a clinic
started earlier by UB's School of
Nursing. Each Saturday morning,
four or five first- , second- and fourthyear medical students attend. They
are joined by a nurse and physician.
The first- and second-year students take histories and vital signs,
then observe as the fourth-year student conducts an examination. They
present their findings to the physician, who then conducts a final examination.
Among the administrative problems faced by student organizers has
been a lack of insurance for physicians who volunteered to attend.
Recently, Project Hope became affiliated with Sheehan Memorial Hospital, which has been rotating physicians to the clinic every other week.
"The credit goes to the medical
students," said Raul Vazquez, M.D.,
of Sheehan's Family Care Center,
who was attending the clinic one
day this spring. Vazquez, a member
ofUB's Class of 1989, said that while
students were interested in such
volunteer work when he was in
medical school , programs like
Project Hope didn't yet exist.

GET HEART SMART

In this four-year-old program,
medical students visit local fifthgrade classes in teams of four or five
to deliver presentations on avoiding heart disease. The 70 participating students, mostly in their first
year, reach several thousand 10and 11-year-olds annually.
"That's the age to get them, when
they're still impressionable and don't
have any heart disease," said Brad
Davis, who ran the program i.n 199293. "We really consider it the purest
form of preventive medicine."
PEDIATRIC CLINICS

STATS

Teen-agers don't like listening to
those they see as adults. But if they're
told something by another student,
particularly if that student is wearing jeans and a t-shirt, the message
might get through.
That's the theory behind Students
Teaching AIDS To Students.
Launched several years ago by the

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About 20 to 30 students per
semester attend pediatric clinics
at the Roberto Clemente and jesse
E. Nash health centers in Buffalo.
They're mostly in their first and
second years, and they help the
health center staff with growth
charts and sometimes with immunizations.
+

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Spoon

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Humor©

ADVICE FROM SOMEONE WHO ' S BEEN THERE

ince this issue of Buffalo Phy sician features topics
on medical school, I started thinking back to those
days. Despite their complications, intricacies, similarities and differences, professors can basically be
divided into five categories:
tf . MIGHTY FAMOUS BIG SHOT

~ - THE DISDAINFUl EGGHEAD
Advantages: His course includes attach-

Advantages: Draws in grant money

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and monolith residents to the
department.
Disadvantages: Speaks with a difficult-tounderstand South African accent,
despite having spent all his life in a
suburb of Cleveland. Choice in
clothing qualifies him as legally blind.
Warning: May be hazardous to your
health.

ing state-of-the-art electrodes to
the lacrimal glands of domestically
raised coyotes, making for interesting chit-chat at family gatherings.
Disadvantages: Hates M.D.s and considers them technicians.
Warning: Sit in the back row and avoid
making eye contact.

A ·THE NOVICE DRONER
Advantages: Meticulously organized

~.PROFESSOR IN TRUCK DRIVER OUTFIT
Advantages: Chain-smoking genius. Car-

handouts make going to class very
unnecessary.
Disadvantages: Includes material that nobody ever heard of, including the
people she is citing. Includes material nobody cares about.
Warning: This is what the boards and
cocktail parties are like.

ries lecture notes in a Metallica
lunchpail.
Disadvantages: Cyanotic mouth breather,
occasionally desaturates while lecturing.

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/!; . PSYCHIATRIST FROM liCHTENSTEIN
Advantages: His three lectures can be

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D.

~ The social worker making rounds
spontaneously combusts from boredom.
~ The patient loses patience and presents hmself to the housestaff.
~ The attending asks you to pull his
finger.
~ Alfred Hitchcock walks through the
group.
~ The team breaks up into small discussion groups in the stairwell.
+

FOR THOSE OF YOU who have friends or relatives
about to attend medical school, here are some
basic rules for success:

summed up in one sentence:
People who are terminally ill often
get depressed.
Disadvantages: See above.
Warning: When you get depressed you
will wait in line with your classmates to see him.

,

~ Avoid

lecture halls.
on rounds, start each sentence with "According to the literature,
occurs in 5% (or 95%)
of the cases."
~ ever say, "I didn't get the lab
results." It's always, "They're not back
yet."
~ Begin rounds by handing out articles , nobody will read them anyway,
so just randomly photocopy them.
~ Grow a beard with no mustache and
nod your head up and down like a toy
dog. (Males only please.)
~ Keep repeating, "great case, good
pathology," until somebody notices
you're naked from the waist up.
~ Offer to look at the smear several
times during rounds while staring at the
lab reports.
~ ~eep referring to your stethoscope
as your pal Hector.
~ When

Stu Silverstein, M.D., president of Standup Medicine
Seminars of San Francisco,
California, lectures
nationwide on
humor in

SIGNS THATYOU ARE BORING ON ROUNDS:
~ You

are a medical student.
~ Twenty minutes into your
presentation the attending
says, "how old was that
patient? "
~ The patient asks you to
leave the bedside because
everyone else left for GI rounds
20 minutes ago.
~ When you present the lab results,
the intern punches a bunch of numbers into his pocket calculator, looks
up and asks if you also get expensive
phone bills.
~ The chief resident pulls you aside
to tell you you're too intense, relax or
he'll give you a wedgie.

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�Mixing medicine and business
VIRGINIA WELDON '62, USES BOTH HER MEDICAL EDUCATION AND CORPORATE
EXPERIENCE AS SENIOR VP FOR PUBLIC POLICY FOR MONSANTO COMPANY

fter listening to a description of
her assignments at the Monsanto
Company, one of the nation's
largest multi-billion dollar enterprises, you might think Virginia
V. Weldon possesses degrees in
chemical engineering, international diplomacy and marketing rather than a
doctorate in medicine from UB.
"I'm expecting a phone call from the
FDA during the interview. If the call
comes, I've got to take it, but I will call
you right back."
Indeed, Virginia Weldon is a busy
person.
As senior vice president, public
policy, for the St. Louis-based company,
the class of '62 alumna is responsible for
corporate communications and government affairs, devoting most of her hectic
schedule to opening new markets and
winning government approval and public acceptance for emerging technologies and products.
"Monsanto markets its products
worldwide, and I have the responsibility to help sell our products and to get
new products approved for sale by the
government," Weldon explains. The
Monsanto Company manufactures and
markets agricultural and chemical products and pharmaceutical and food ingredients. Some of its best known products include Roundup herbicide, Ortho
lawn and garden products and
NutraSweet.
Weldon never saw herself abandoning the operating room for the corporate
boardroom. "When I went to medical

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school, I was thinking about being a
practicing physician. I loved surgery. I
really enjoyed surgery in my junior year
at the E.]. Meyer Memorial Hospital,"
Weldon said.
"And we had wonderful people teaching physiology. I remember going to
parties and on picnics with Dr. john
Boylan and with other faculty and students. It was a wonderful time. The four
best years of my life," she adds.
Following an internship and residencyin pediatrics at The johns Hopkins
Hospital in Baltimore, Weldon completed a three-year fellowship in pediatric endocrinology at The johns Hopkins
University School of Medicine.
Shortly thereafter, Weldon joined the
faculty of the School of Medicine at
Washington University in the department of pediatrics. It was there that her
interests in medicine began to shift to
matters of public policy.
"I became involved with public affairs as a member of the Endocrine Society and the Society for Pediatric Research with issues concerning funding
for research and the ethical treatment of
human subjects," Weldon says. After
serving as co-director of the division of
pediatric endocrinology and metabolism, Weldon was appointed assistant to
the vice chancellor of medical affairs.
The metamorphosis from physician
to businesswoman was well underway.
Weldon was named deputy vice chancellor for medical affairs and vice president of the medical center at Washington University School of Medicine and

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Medical Center in 1967. She joined
Monsanto as vice president, scientific
affairs and was quickly promoted to vice
president, public policy, serving in that
capacity from August 1989 to October
22, 1993, when she began her present
position with Monsanto.
One of the greatest challenges facing
Monsanto, Weldon says, is to build public trust.
"Science-based companies like
Monsanto have a responsibility to assure
the public that the science on which new
products are based is of the highest caliber. It is imperative that our science and
assessment procedures are beyond reproach in order to be credible and
trusted."
Weldon's education and experience
as both a physician and corporate executive have helped shape her views regarding health care and, in particular, with
the congressional debate regarding health
care reform. "It's a very complicated subject, partly because of the size and complexity of the health care system, the
entrepreneurial spirit of our country and
the public's expectation for continual
improvement of medical care."
It will be very hard, she adds, to
reform the nation's health care system in
"one fell swoop." Instead, Weldon said
attention should be paid to aspects of the
system that are "broken."
"We need portability of insurance
coverage and we need to provide insurance for those who don't have coverage.
And it must be affordable," she maintains.

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"One of the issues being overlooked
in this debate is the jobs involved with
health care services. No one is considering the consequences to the academic
medical centers, pharmaceutical companies and insurance companies,"
Weldon says.
When asked specifically about regulatory delays that affect the timely approval of new pharmaceuticals, Weldon
said, "One way to help this country
maintain its competitive edge in pharmaceutical discovery is to provide the
FDA with enough funds to work efficiently and effectively, to give them resources to hire the scientists they need
to evaluate new drug petitions, and to
make sure the agency is free from political influence."
But, she added, "Our congressional
leaders have not seen fit to provide the
additional funds the FDA needs. There
are numerous, geographically separate
facilities for the FDA in Washington,
many of them antiquated. There is certainly a need for more resources."
As a spokesperson and policymaker
for a major international company,
Weldon has become, by default and not
by design, a high profile example of a
successful businesswoman and she has
strong opinions regarding opportunities afforded to all individuals within
corporate America and within her own
company.
"What happens to you, whether you
succeed or fail, depends upon you as an
individual.
"I don't believe that women who become militant about their role can contribute effectively. Women who make
positive contributions make it easier for
other women who will come after them,"
Weldon said.
"My guess is that women who employ 'sharp elbows' in an attempt to
further their careers actually make

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" SCIENCE-BASED

COMPANIES LIKE

MONSANTO HAVE A

RESPONSIBILITY TO ASSURE

THE PUBLIC THAT THE

SCIENCE ON WHICH NEW

PRODUCTS ARE BASED IS

VIRGINIA WELDON

OF THE HIGHEST CALIBER. "

that was purposeful- it happened because, historically, medicine was dominated for so long by men."
ot surprisingly, Weldon has taken
an active role in promoting the national
effort on women's health issues and, in
1993, was appointed by the National
Institutes of Health to serve as Chairman of the Women's Health Initiative
Program Advisory Committee.
UB is one of 16 vanguard clinical
centers participating in NIH's landmark

things harder ," Weldon continued.
"Monsanto is trying to find qualified
women and minorities in order to
achieve a diverse work force and to
provide an opportunity for everyone to
succeed. Monsanto is very serious about
diversity. "
But Weldon also acknowledged the
difficult role many women face in advancing their careers. " ... probably every woman in any kind of job that is
viewed as non-traditional has felt
marginalized or overlooked .. .. we must
work very hard to change the culture in
our (nation's) businesses and institutions, but it takes a long time."
An area in which Weldon sees steady
progress, however, is in women's health
initiatives. "Women's health has been
neglected for a long time. I don't think

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studyofwomen~h~hh .

As for the future, Weldon says she is
constantly challenged in her job at
Monsanto and is not thinking about any
more career changes. "Someday," she
said wistfully, "''d like a little more time
+
for golf and travel. "
-

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SIGURDSON

�~-··········· · ···········································································

IE

Kasstrer '53, delivers Stockton Kimball Lecture
1991 DISTINGUISHED MEDICAL ALUMNUS RETURNS FOR SPRING CLINICAL DAY
TO SPEAK ON " CLINICAL REASONING : TEACH I NG I T AND LEARN I NG IT"

"

espite or perhaps because of all
sorts of technological advancements, our cognitive skills remain
the preeminent part of our work
as physicians,"] erome P. Kassirer,
M.D., editor-in-chief of The New
England journal of Medicine, told the
audience gathered to hear him give the
annual Stockton Kimball Memorial Lecture at this year's
Spring Clinical Day,
held April 30 at the
Buffalo Marriott.
"But despite the
importance of the
diagnostic process,
we spend precious
little time trying to
understand it," he
said.
Kassirer's talk,
"Clinical Reasoning:
Teaching It and
Learning It," focused on what he
called "the mental
process that physicians use when they
perform the task of diagnosis."
Robert Reisman, M.D., president of
the UB Medical Alumni Association and
a longtime friend and schoolmate of
Kassirer, introduced Kassirer and praised
him as "everything a physician should
be- a clinician, teacher and researcher
who is dedicated to medicine. He's an
excellent physician, often referred to in
those most admirable of terms as a
'physician's physician,"' Reisman told
the more than 300 people, including UB

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President William Greiner, who attended.
Kassirer, a 1953 UB alumnus who
earned his medical degree from the UB
School of Medicine and Biomedical Sciences in 1957, began by pointing out
that he felt it was a great privilege to be
giving the Stockton Kimball Memorial
Lecture partly because Kimball was dean

of UB's medical school when Kassirer
had been a student there. Kassirer praised
UB and the Buffalo area, saying "I treasured my experience in medical school
and the two years I spent at Buffalo
General Hospital."
Regarding the diagnostic process,
Kassirer said, "The more we study it, the
less likely we are to make errors. I want
to explain how the process goes, as well
as the faults that affect even the best of us."
Kassirer pointed out that while phy-

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sicians often think of themselves as the
only people who use diagnosis, nothing
could be further from the truth. Diagnosis is a process used by all sorts of
people, from politicians to mechanics,
Kassirer said.
The diagnostic process involves, first
of all, inferences that are made from
observable facts about the nature of a
system malfunction,
Kassirer said. Such
inferences yield "a
series of provisional
approximations that
are revised continually," he said. But he
added that it was important to pay attention to the distinction between a perception and an inference, and to note
how much inference
goes on in any act of
perception. "As an
example, if you see a
ball bounce into the
street, that perception may cause you to immediately slow
down your car because of your inference that the ball could be followed by
a child," Kassirer said.
Kassirer pointed out that there are
two basic types of problem-solving
methods, which he termed "weak" methods and "strong" methods. Weak methods are general problem-solving methods that do not depend on a particular
domain of expertise, are widely applicable across different problem areas and

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are characteristic of novice rather than normal and abnormal findings. The com- ciples for teaching clinical problem-solvexpert behavior, Kassirer said. Strong peting hypotheses also have to be proved ing, which included using case presenmethods, he said, are methods used by false at this stage, Kassirer said.
tations and giving students data in
domain experts and involve rapid recResearch on the diagnostic process "chunks" that allows them to particiognition of patterns and efficient for- has a number of important uses in edu- pate in the diagnostic process. Kassirer
mulation of problems in "semantically cation, Kassirer said. It enables better stressed the importance of using real
meaningful chunks." Such methods go teaching of that process, and helps stu- cases in order to reflect what he called
directly toward the solution of particu- dents learn how to recognize clusters of "the messiness of clinical medicine."
lar problems and are domain-depen- cues at the beginning of the process. Other basic principles included stressdent and narrowly applicable, Kassirer Research on diagnostics also helps ex- ing causal relations when possible, and
said.
plain the rationale behind the tradi- identifying for students the reasoning
Kassirer said four basic components tional routine "workup" with which strategies employed, as well as potential
comprise the diagnostic process: hy- physicians prepare for every diagnosis, errors in reasoning.
pothesis generation, context formula- Kassirer said.
It is essential, Kassirer said, to teach
tion, hypothesis refinement and hypothBut research on diagnostics also helps by example. Students learn reasoning
esis verification.
teach students that in certain cases it by seeing others reason, he said.
Generating the initial hypotheses and may be appropriate to skip around, to
The clinical reasoning process can
formulating a context for those hypoth- start from laboratory data, or, in the help minimize errors at all points in
eses provide a model for gathering more case of urgent problems, to interrupt diagnosis, and can help avoid such coninformation about the problem, Kassirer normal processes of information, sequences of error as delays in treatsaid. Often based on minimal cues that Kassirer said.
ment, unnecessary exposure of patients
come in clusters, these initial hypothFurther, students can be taught to to various tests, inappropriate treatment
eses "can range from the general to the avoid certain heuristics that can lead to and the anxiety that results from each of
specific," Kassirer said. "At this stage, error. Teaching the quantitative ap- these consequences, Kassirer said.
hypotheses are intermingled in a pecu- proach to combining clinical data, as
"All this will hopefully lead us to a
liar sort of way."
well as the use of pre-compiled, condi- general model of problem-solving that
After developing a context for un- tion-action pairs, can also be improved can help us identify good or bad reasonderstanding why one has come to these by research on diagnostics, Kassirer said. ing," Kassirer said.
+
initial hypotheses, the problem solver
Kassirer listed a number of basic prinBY
MARK
W
ALLACE
enters the stage of hypothesis refinement, Kassirer said. At this stage, various hypotheses are deleted, added or
made more specific. This phase is dominated by probabilistic reasoning as the
problem solver tries to determine which
of the generating hypotheses are most
likely correct, Kassirer said. By using
pre-compiled rules and information
about the source of various problems,
the problem solver tries to achieve a
hypothesis that has near certainty, he
said.
When one hypothesis clearly begins
to dominate, the problem solver has
reached the stage of hypothesis verificaThis year's senior medical students were honored by the Alumni Association and President and
tion, Kassirer said. The hypothesis has
Mrs. William Greiner at the annual Senior Reception last february 26 at the Buffalo Hilton.
to be tested for coherence and accuracy,
and to see whether it explains both

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.

I

• A test of the effectiveness of hormone-replacement therapy in reducing
the risk of heart disease and osteoporosis.
• A study of the effect of a low-fat diet
on the risk of cardiovascular disease and
breast and colorectal cancer.
• An investigation of the effectiveness
of calcium and vitamin D supplements
in reducing osteoporosis and colorectal
cancer.
In Western New York, 14,000women
will be recruited over three years to take
part in the clinical trials.
The observational study will follow
women over eight to 12 years to try to
determine physiological and lifestyle
factors that can affect health. Participants in this phase - about 2,200 of
them in Western New York - initially
will give detailed medical histories and
then will be contacted every three years
to update their information.
Women interested in volunteering
for the study should call the Women's
Health Initiative clinical center at
(716)829-3128.
+

Women's Health Initiative begins
MEDICAL SCHOOL AMONG 16 VANGUARD CENTERS TO
PARTICIPATE IN LANDMARK STUDY OF WOMEN

Trevisan. "We will be taking part in a
history-making study that will answer
very important questions regarding the
well-being of women.
"In addition, information we gain
from the central study will be the seed
for other studies that will contribute to
the knowledge of women's health. It is
also creating a number of new jobs, and
more jobs will be created as other studies are generated.
"This is a massive undertaking," he
added, "and we will need the cooperation of many people, particularly the
women volunteers, to make the study a
success."
The study itself will be conducted in
two parts- clinical and observational.
The clinical component will involve
three investigations:

esearchers at UB kicked off the
major recruitment drive for the
Buffalo portion of the $625 million Women's Health Initiative
with the February 25 grand opening of the new women's clinical
center.
The Women's Health Initiative,
funded by the National Institutes of
Health, is the largest clinical health study
ever undertaken in the United States.
Approximately 160,000 women between
the ages of 50 and 79 at 45 centers will
take part in identical studies designed to
investigate the causes of heart disease,
breast and colorectal cancers and
osteoporosis in older women and test
the effectiveness of various treatments.
UB, selected as one of the 16 lead
research centers in the 12-year study,
will receive $11 million over the life of
the project.
Headquarters for the UB clinical trials is a newly renovated 5,700-squarefoot clinical center in Farber Hall on the
South Campus. The grand opening featured a ribbon-cutting ceremony with
UB provost Aaron N. Bloch; John
Naughton, M.D., vice president for clinical affairs and dean of the School of
Medicine and Biomedical Sciences;
Mauriz\_9 Trevisan, M.D., principal investigator for the UB portion of the
study ana chair of the Department of
Social and Preventive Medicine; Jean
Wactawski-Wende, Ph.D., professor of
social and preventive medicine and one
of the UB investigators; and Congressman Jack Quinn, R-Hamburg.
"This is a wonderful opportunity for
Western New York and UB," said

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Women's Health
Initiative

MaurizioTrevisan,M.D.,andJeanWadawski-Wende,Ph.D.,atthenewdinicalcenter.

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Dean honored by Asian Amertcan
Physicians'Association recently
avid C. Dean, M.D., clinical professor of medicine , received the
Asian American Physicians'
Association's first "Friend of the
Asian American Physicians' Association" award at a dinner held
last fall.
Dean, who is
also chief of cardiac rehabilitationatBuffalo VA
Medical Center
and co-medical
director of the
cardiac rehabilitation unit at The
Buffalo General Hospital, is a fellow of
the American College of Physicians, the
American College of Cardiology and the
College of Chest Physicians.
+

Lockwood assumes new PSR post
he board of directors of Physicians
for Social Responsibility (PSR) has
named Alan H. Lockwood, M.D.,
UB professor of neurology and
director of the Buffalo VA Medical
Center's Center for Positron Emission Tomography, its 1994 president.
Founded in 1961, PSR is a leading
national organization of more than
20,000 health professionals and supporters working in 90 chapters across
the country for the elimination of nuclear
and other weapons of mass destruction,
the achievement of a sustainable environment and the reduction of violence
and its causes. PSR is the U.S. affiliate of
International Physicians for the Prevention of Nuclear War, recipient of the
1985 Nobel Peace Prize.

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Lockwood has been a member of
PSR for over a decade , serving in its
house of delegates from 1986 to 1989,
and as chair of that body from 1987 to
1989.
He was elected to the national board
of directors in 1989 and served as its
treasurer for two years before being
selected as president-elect in 1993 .
Lockwood also serves on the editorial
board of The journal of Medicine and
Global Survival.

Lockwood has been a leading PSR
spokesman against the Strategic Defense
Initiative. He has also been instrumental in the development of PSR's programs to address environmental health
+
threats.

Curtis Mettlin, Ph.D., (left) receives award fram
Irvin Fleming, M.D., ACS president.

Curtis Mettlin receives prestigious
ACS Volunteer Leadership Award
urtis ]. Mettlin, Ph.D., chief of
epidemiologic research and director of the department of cancer
control at Roswell Park Cancer
Institute, received the National
Volunteer Leadership Award from
the American Cancer Society (ACS) .
The award is given annually to ACS
volunteers whose service to the national
organization has been long and distinguished.
Mettlin has written more than 180
articles, chapters and books on cancer.
He was the principal investigator of the
ACS's multi-institutional study that
found the use of ultrasound and the
prostate-specific antigen blood test in
conjunction with digital rectal exam
significantly increases the detection rate
for prostate cancer.
Mettlin has served on many national
ACS committees and task forces dealing
with issues as diverse as cancer detection
and treatment, public and professional
cancer education and developing strategies for all Americans to gain access to
+
cancer treatment and prevention.

Carl Granger wins Frank Krusen
Award for rehabilitation medicine
arl V. Granger , M.D., associate
chairman of the department of rehabilitation medicine, has been
awarded the Frank H. Krusen
Award for outstanding contribution to the field of rehabilitation
medicine by the American Academy of
Physical Medicine and Rehabilitation.
Granger, who is also director ofUB's
Center for Functional Assessment Research and co-director of the Multiple
Sclerosis Center, was presented the
award at the academy's annual meeting
last November. The award was established nearly 25 years ago to honor one
of the academy's founding fathers.
Granger served as president of the
academy from 1975 to 1976. He is the
author of more than 90 publications
and co-developer of the Functional Independence Measure and the Uniform
Data System for Medical Rehabilita+
tion.

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�developed a powerful system that mimics many types of brain damage ."
Langan observes that the close resemblance of the cultures to damaged
$534 ,000 WILL FUND RESEARCH INTO ASTROCYTE
brain was "a fortunate surprise. "
GROWTH AND RECOVERY FROM BRAIN DAMAGE
But his lab's efforts to sort out the
biochemical controls were even more
niversity at Buffalo neurologist percent of all approved grants, resulting surprising. Studying a class of cell-signaling proteins known as G proteins,
Thomas]. Langan, M.D., has re- in five years of funding.
The NIH reviewers described the researchers discovered that the modiceived a $534,000 National Institutes of Health grant to explore Langan's application as a "very strong fication of these proteins by by-prodthe link between astrocyte growth proposal which emphasizes a very im- ucts of cholesterol metabolism deterand recovery from brain damage. portant aspect of astrocyte cell biology. " mines whether the astrocytes divide or
Studies by others have shown that differentiate.
"One of the most satisfying (and rare)
"We showed that this modification,
things that can happen in biomedical newborn astrocytes in culture divide on
called
isoprenylation, determines
research is for a focused area of labora- the normal developmental schedule,
whether
the astrocytes commit to divide
tory work to rapidly provide clues to which in the intact brain is the main
several important clinical problems," reason for the growth of the brain after or assume a more differentiated shape.
In other words, there seems to be a
Langan, associate professor of neurol- birth.
common
biochemical control mechaLangan discovered that the cultured
ogy and pediatrics and an attending
nism for these two critineurologist at The
cal aspects of astrocyte
Children's Hospital of
function. "
Buffalo , said.
The NIH grant will
Langan's research foallow
Langan and felcuses on astrocytes, the
low UB researchers
star-like brain cells that
Commitment
RPoint
Ronald Berezney, Ph.D. ,
"are by far the most nuStart Glls
professorofbiology,and
merous cells in the brain,
Robert]. Plunkett, M.D. ,
even though their funcassistant
professor of
Flat,
tions were mysterious
Stellate,
Proliferating
Arrested
neurosurgery
, to study
Astrocyte
until around 20 years
Astrocyte
this
mechanism
and to
ago.
Modification
of
the
cell-signaling
proteins
determines
whether
the
astrocytes
divide.
determine
how
it ap"During the last deplies to the problem of
cade in particular ,"
brain
injury
and
recovery.
Langan explains, "there has been in- astrocytes further resemble their counThe
significance
of the apparent link
creasing evidence that astrocytes may terparts in the intact brain by maintainbetween
the
role
of
isoprenylation in
be involved in controlling the fate of ing the capacity to divide again for many
and
differentiation ,
cell
division
control
neurons , both in terms of normal devel- months.
Langan
says,
"lies
in
the
potential to
opment and response to injury. "
He also found that when the cultured
But, he notes, very little is known astrocytes are stimulated to divide later, manipulate the astrocyte responses once
about what coordinates the complex they act exactly as cells that respond to the control mechanisms have been defined.
behaviors of astrocytes themselves many types of brain injury.
"Since astrocytes play a key role in
an area where Langan's recent findings
"When stimulated," Langan says,
responses
of human brain to many types
lie that has drawn interest from the "these cultured astrocytes express the
of
injury,
ranging
from trauma and mulationalinstitute of eurologic Disor- same proteins on the same time schedtiple
sclerosis
to
Parkinson's
Disease, the
ders and Stroke. At a review meeting last ule as the cells in intact brain that are
autumn , the NIH branch ranked involved in reactive gliosis, the hall- ability to control their actions could
+
Langan's grant application in the top 4 mark of brain injury. Therefore, we have have immense practical benefit."

UB neurologist wins NIH grant

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UB has 28 faculty physicians
listed in this year'sedition of
"Best Doctors in America"
wenty-eight faculty members at
the School of Medicine and Biomedical Sciences have been included in the second edition of
The Best Doctors in America, a directory of the "best and brightest"
in the medical profession.
Best Doctors lists 7,200 physicians in
more than 50 specialties - approximately 2 percent of the nation's 350,000
practicing physicians.
The listing is compiled from interviews with thousands of specialists
throughout the country who were
asked to rate the clinical ability of their
peers.
UB faculty members who are included
in Best Doctors are Mark Ballow, M.D.,
professor of pediatrics and chief of the
division of allergy and immunology;
David W. Bentley, M.D., former professor of medicine, director of the Multidisciplinary Center on Aging and director
of the division of geriatrics; Clara D.
Bloomfield, M.D., professor of medicine;
Lawrence B. Bone, M.D., associate professor of orthopaedic surgery; Edward L
Bradley, Ill, M.D., professor and vice
chair of surgery; Linda S. Brodsky, M.D.,
associate professor of otolaryngology
and pediatrics; Michael E. Cohen, M.D. ,
professor and chair of neurology; Patrick
Creaven, M.D., associate research professor of pharmacology; Patricia Kresse!
Duffner, M.D. , professor of neurology
and pediatrics; Bradley P. Fuhrman,
M.D., professor of pediatrics.
Also, Robert Gillespie, M.D. , professor and chair of orthopaedic surgery;
Marion Zucker Goldstein, M.D., clinical associate professor of psychiatry;
Daniel Green, M.D., professor of pediat-

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Fuhrman

Gillespie

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Herzig

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Jacobs

Middleton

Min dell

Nemoto

Pincus

Reisman

Rossi

Stapleton

Voorhess

Ballow

Bentley

Cohen

Creaven

Green

MacGillivray

orthopaedics; Takuma emoto, M.D.,
research associate professor of surgery;
Stephanie Pincus, M.D., professor and
chair of dermatology; Derek Raghavan,
M.D., professor of medicine; Robert
Reisman, M.D., clinical professor of medicine and pediatrics; Thomas M. Rossi,
M.D., associate professor of pediatrics; F.
Bruder Stapleton, M.D., A. Conger
Goodyear professor and chair of pediatrics; and Mary Louise Voorhess, M.D.,
+
professor emeritus of pediatrics.

rics; Saul P. Greenfield, M.D. , associate
professor of urology; Geoffrey P. Herzig,
M.D., professor of medicine; L elson
Hopkins, M.D., professor and chair of
neurosurgery; Lawrence D.jacobs, M.D.,
professor of neurology; Kenneth A.
Krackow, M.D., professor of orthopaedics;
Margaret MacGillivray, M.D., professor of
pediatrics.
Also, Elliott Middleton, Jr., M.D.,
professor of medicine and pediatrics;
Eugene R. Mindel!, M.D., professor of

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.

I

Judah Folkman, M.D, delivers 1994 Harrington Lecture
NOTED RESEARCHER DISCUSSES GROUNDBREAKING THEORY OF ANGIOGENESIS
AS WELL AS CLINICAL BREAKTHROUGHS USING ANGIOGENESIS INHIBITORS

udah Folkman, M.D. , whose research led to the development of
the theory of angiogenesis, delivered the 1994 D.W. Harrington
Lecture, "Clinical Applications of
Angiogenesis Research," discussing the history of his work with
angiogenesis, as well as some recent
clinical breakthroughs that saved the
lives of children with tumors which, in
the past, would have been fatal.
Charles Paganelli, Ph.D., interim
chair of the UB Department of Physiology, introduced Folkman, who is the
julia Dyckman Andrus professor of pediatric surgery at Harvard Med1cal
School. Paganelli praised Folkman's interest and achievement in a wide range
of areas, including not only the theory
of angiogenesis but also development of
the contraceptive Norplant and of implantable cardiac pacemakers. Paganelli
further praised Folkman for offering
fundamental insights into the growth of
capillary networks.
Folkman, who is also professor of
anatomy and cell biology at Harvard, is
credited with discovering the mechanisms of angiogenesis, a concept that
holds that solid tumor cancers may develop as a result of chemical signals
released by tumor cells that cause the
blood vessels in surrounding tissue to
grow. Research is under way worldwide
investigating angiogenesis and its relation to cancer and many other diseases.
The theory of angiogenesis has been
guided by two central questions ,
Folkman said. "First is the question of
how angiogenesis, or blood vessel
growth, is turned off in many physi-

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Judah Folkman, M.D.
ological states," he said. "Then there's
the opposite question: why is it not
turned off in many pathological states,
and why does it persist to the detriment
of its host?"
In attempting to answer these questions, angiogenesis research has focused
on three basic areas, Folkman said: what
cancer would be like in the absence of
angiogenesis, what would human tissue
be like without it and what would happen if all communication between tumor cells in the human body could be
stopped, Folkman said.
Folkman began his research into
angiogenesis in the 1960s while serving
a two-year term in the U.S. Navy at the
Bethesda National Naval Medical Center. After completing an experiment to
study hemoglobin solutions by infusing
the thyroid glands of rabbits with those
solutions and then measuring thyroid
function, Folkman and his colleagues
began to ask whether isolated glands

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could support growth, he said.
That research led Folkman and his
colleagues to publish the hypothesis
that tumor growth was angiogenesisdependant, Folkman said. In simplest
terms, he said, that hypothesis stated
that after a tumor exists, every further
increase in tumor mass must be preceded by the proliferation of new capillary blood vessels that converge upon
the tumor. "Our hypothesis led to many
experiments, and the field has now
moved in a number of basic directions,"
Folkman said.
In the 1970s, Folkman began to work
on isolating a variety of angiogenesis
factors. After some years of failed work,
Folkman finally managed to compile a
list of those basic factors . "The list had
great transformative pow ers for
angiogenesis research," Folkman said.
"It transformed my critics into my competitors."
But it wasn't until1990 that researchers finally gained direct evidence that
tumor growth was angiogenesisdependant, Folkman said. "Only four
years ago did our many years of lab
research begin to be translated to clinical trials," he said.
Recent clinical trials have fallen into
three basic categories, Folkman said:
trials of angiogenic peptides that accelerate angiogenesis, the administration
of angiogenesis inhibitors for patients
with tumors and trials that attempt to
understand the principles of prognostic
tests in cancer.
The discovery of angiogenesis inhibitors has taken place "primarily under
weird circumstances," Folkman said,

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tion is a not-for-profit organization that
brings together medical education and
research, health care providers, health
care manufacturers and health care-related businesses to explore issues facing
the industry.
+

Health Care Industries Association
presents Awards for Excellence

suggesting that many inhibitors were
discovered by accident rather than by
controlled experiment. 1989 saw the
first successful treatment of universally
fatal pulmonary hemangioma by the
angiogenesis inhibitor alpha-interferon.
On hearing the news, Folkman and others were understandably skeptical, he
said, but further investigation proved
the treatment was valid.
The administration of alpha-interferon has already saved 53 people, mostly
children, who otherwise would have
died of their tumors , Folkman said. "A
whole series of tumors can now be held
to dormancy by angiogenesis inhibitors," he said.
"We're beginning to think that in the
near future cancer patients, on their
first biopsy, will have angiogenesis profiles perfomed," Folkman said. "They
will also have long-term angiogenesis
treatment to extend the dormancy of
their cancer. "
Folkman served as surgeon-in-chief
at Children's Medical Center in Boston
for 14 years before resigning in 1981 to
conduct research full- time after his 1980
appointment to Harvard. A member of
the National Academy of Sciences,
Folkman counts among his many honors a 10-year Merit Award from the
National Cancer Institute in 1989, the
American Cancer Society's Medal of
Honor for basic science, Israel's Wolf
Prize in Medicine and the Christopher
Columbus Award in Biomedical Research from the National Institutes of
Health.
The Harrington Lecture is sponsored
by the School of Medicine and Biomedical Sciences. The D.W. Harrington Lecture Fund was established in 1886 by
Devillo White Harrington, M.D., an 1861
graduate of the UB medical school and a
professor of genito-urinary and vene+
real diseases from 1886 to 1905.

oswell Park Cancer Institute ,
Herbert Hauptman, Ph.D., and
Wilson Greatbatch were among
the individuals and institutions
recognized by the Health Care Industries Association's first Annual
Awards for Excellence.
The Economic Impact Award for
Excellence was awarded to Roswell Park
Cancer Institute. The award was cosponsored by the Western New York
Economic Development Corporation.
Special President's Awards were presented to Nobel Laureate Hauptman,
UB research professor of biophysical
sciences, and Greatbatch, adjunct professor of electrical and computer engineering, for their dedication to the Health
Care Industries Association and their
overall contributions to the health care
industries of Western New York.
UB President William Greiner delivered the keynote address.
The Health Care Industries Associa-

Nolan named chair of College of
Physicians Board of Regents
ames P. Nolan , M.D. , professor and
chair of the Department of Medicine has been elected to a one-year
term as chair of the American College ofPhysicians Board of Regents.
Nolan has served on the 26member board since 1989 and was vice
chair in 1993. Prior to joining the board,
he was the society's governor for New
York State for four years , winning the
Governor of the Year Award in 1988. He
also served as president of the New York
State chapter from 1987 through 1988.
In addition to his UB appointments,
Nolan serves as director of medicine at
Erie County Medical School.
+

At left, Herbert Hauptman, Ph.D., and Wilson Greatbatch receive Health Care Industries awards.

LLACE

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UB signs unique clinical psychiatry agreement
BUFFALO PSYCHIATRIC CENTER , WESTERN NEW YORK CHILDREN'S PSYCHIATRIC
CENTER JOIN THE UNIVERSITY'S MULTIDISCIPLINARY CLINICAL TEACHING SITES

the state Office of Mental Health; john
Naughton, M.D., vice president for clinical affairs and dean of the School of
Medicine and Biomedical Sciences;
George Molnar, M.D., UB associate professor of psychiatry and executive director of the Buffalo Psychiatric Center;
and Allen R. Morganstein, M.D., clinical director of the Western ew York
Children's Psychiatric Center.
UB, ~rimarily through its department
of psychiatry, has used the two facilities
to train students and residents for some
time, but never had a formal working
agreement with them. As a result of the
agreement, a 10-member committee
from the three institutions will be formed
to oversee the educational and research
programs the facilities operate.

he Buffalo Psychiatric Center and
the Western New York Children's
Psychiatric Center became formal
UB clinical teaching sites in a contract-signing ceremony held in
March.
The five-year renewable agreement
between UB and the New York State
Office of Mental Health opens new teaching and multidisciplinary research opportunities at the centers for UB faculty,
students and medical residents, and provides the centers' physicians and staff
access to UB's faculty and research facilities.
Participating in the signing were UB
President William R. Greiner; Philip B.
Wels, M.D., chair of the UB Council;
Richard Surles, Ph.D., commissioner of

From left: William Greiner; Ri(hard Surles, Ph.D.; John Naughton, M.D.; Philip Wels, M.D.;
Allen Morganstein, M.D.; and George Molnar, M.D., at the March signing (eremony.

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The new contract opens the centers'
doors to the UB schools of dental medicine, nursing, pharmacy and health related professions, as well as to faculty
and graduate and undergraduate students in clinical psychology and social
work. The centers will provide equipment, lecture rooms and laboratories, in
addition to faculty, for teaching and
joint clinical research activities.
"Collaboration with local providers
has already proven to be an outstanding
model for clinical training in UB's School
of Medicine and Biomedical Sciences,"
Greiner stated. "We are delighted that
the Buffalo Psychiatric Center and the
Western New York Children's Psychiatric Center will join UB's group of clinical affiliates.
Greiner praised Surles for his support, adding, "This sort of joint effort of
the state, local providers and the university can do much both to enrich UB's
education and training programs and to
enhance care delivery for our fellow
Western New Yorkers."
Naughton, who will be UB's primary
liaison with the centers and was instrumental in negotiating the agreement,
said the relationship is a welcome step
in the university's efforts to expand opportunities for clinical teaching and research for its students and faculty.
"This contract confirms that these
two psychiatric centers are very important facilities in our community,"
Naughton said. "The opportunities the
agreement presents for interdisciplinary
research and innovative learning are
enormous. The inclusion of these facilities in the university family will add

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�The images
assist in pre-operative planning
of the implant
site, direct visualization of how
well the implant
will fit and ascertain the need
for building up
bone tissue before implantation.
DelBalso is currently president of the
American Board of Oral and Maxillofacial Radiology. He is the only physician
in the U.S. who is board certified in both
medical diagnostic radiology and oral
maxillofacial radiology.
+

significantly to our educational opportunities, particularly in the areas of pediatric psychiatry and in the care of the
chronically ill. "
The affiliation offers a model that
deserves replication in other areas of the
state, Surles noted. "This agreement not
only creates outstanding educational and
research opportunities for university
students and the psychiatric centers'
staffs, it provides the agency with a
formal role in academic training - a
first for the state Office ofMental Health."
Molnar praised the mutually beneficial agreement. "Our expectations are
high ," he said, "and our enthusiasm is
great. We look forward to many new
opportunities for joint teaching andresearch activities , and to increased collaboration with the university's schools
and departments. "
Morganstein said, "The agreement will
be beneficial to the university, as well as
to the Western New York Children's
Psychiatric Center, in providing opportunities for professional growth of staff.
Ultimately, this will filter down to the
community by providing enhanced clinical services."
+
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Convenient Downtown
Location
Quick Metro Ride to
Main Street Campus and
Medical School
'i(

Close to Buffalo General,
Roswell, ECMC and
Children's Hospitals

tephen B. Edge, M.D. , chief of the
breast division of the department
of surgical oncology at Roswell Park
Cancer Institute , has been appointed to a panel of health care
experts and consumers to evaluate
breast cancer treatment in New York
State.
The new Breast Cancer Treatment
Quality Advisory Panel will gather data
on treatment strategies, measure the
quality of breast cancer treatment in
New York and recommend ways to improve its effectiveness.
Edge, the only Western New Yorker
appointed to the advisory panel, has
served as chief of RPCI's breast division
since 1992. He is an investigator with
the National Surgical Adjuvant Breast
and Bowel Project. A fellow of the American College of Surgeons, Edge is a member of the American Society of Clinical
Oncology and the Society of Surgical
Oncology.
+

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Conference Planning
Professionals

Stephen Edge named to state
breast cancer advisory panel

ngelo M. DelBalso, M.D., D.D.S. ,
interim chairman of the department of radiology, recently addressed the Third International
Congress of the Dutch Society of
Oralimplantology. DelBalso, clinical director of Erie County Medical
Center's department of radiology, explained how readily available computer
software can be used for three dimensional imaging in connection with permanent tooth replacements.

u

18,000 Square Feet
of Meeting Space

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DelBalso addresses Dutch Society
of Oral lmplantology Congress

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UB wins federal rehabilitation research grant
$2 .4

MILLION WILL FUND NATION'S FIRST CENTER TO DEVELOP OBJECTIVE
STANDARDS TO MEASURE DISABILITY AND ITS EFFECTS

he University at Buffalo has received a $2.4 million federal grant
to establish the nation's first center charged with developing objective standards to measure disability and its effects, and to assess
the effectiveness of rehabilitation programs designed to treat disabilities and
improve function.
The new Rehabilitation Research and
Training Center on Functional Assessment and Evaluation of Rehabilitation
Outcomes will fund seven research
projects over the next four years. The
work will involve faculty from UB's department of rehabilitation medicine and
its schools of nursing, health related
professions and architecture and planning.
The new center will also collaborate
with five other academic rehabilitation
centers - Craig Hospital in Englewood,
Colorado; Rehabilitation Institute of
Chicago; Kessler Institute for Rehabilitation, Inc., West Orange, New jersey;
The Ohio State University; and Brown
University. D'Youville College in Buffalo will work with the UB center to
develop a curriculum in functional assessment studies.
"Our charge is to introduce a more
scientific approach to measuring the
abilities and limitations of people living
with handicaps," said Glen E. Gresham,
M.D., professor and chair of the department of rehabilitation medicine and the
grant's project director.
"We hope to develop uniform standards for measuring disability and the
methods disabled people use to adapt
that everyone accepts and understands."

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Glen Gresham, M.D.
Currently, there is no system to classify disabilities according to severity, or
to a standard rehabilitation regimen
based on severity, Gresham said.
"In this era of health care reform," he
noted, "the field of rehabilitation medicine must be able to prove the value of
its services. Research conducted through
this new center will enable us to define
disabilities clearly, tell which rehabilitation approaches are most valuable and
will allow rehabilitation workers across
the country to use a common language
to describe patients and their problems."
The center's seven research projects
and the academic rehabilitation centers
involved are:
• Handicap assessment - to improve
the classification of handicaps (UB and

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Craig Hospital).
• Relationship of treatment to outcomes- to determine how much rehabilitation programs help patients (UB,
Rehabilitation Institute of Chicago and
Kessler Institute for Rehabilitation) .
• Measuring handicapping environments - to identify barriers that produce handicaps and measure the extent
of their effect (UB).
• Characteristics of effective, efficient
medical rehabilitation programs - to
determine why one program works better than another (UB, Rehabilitation
Institute of Chicago and Kessler Institute for Rehabilitation).
• Determining which functional assessment measure can best be applied to
persons with traumatic brain injury (UB

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�Msall elected to membership in
Society for Pediatric Research

and The Ohio State University).
• Validity of telephone interview versus personal interview for completing
the Functional Independence Measure,
a score used to follow a patient's progress
and measure the outcomes of a rehabilitation program (UB).
• Determining whether social support
enhances rehabilitation outcomes (UB ,
Kessler Institute for Rehabilitation and
Brown University) .
The grant also calls for developing a
curriculum in functional assessment
studies, which will be offered initially
by UB and D'Youville College; writing a
training manual on using functional
assessment instruments; and hosting a
national conference on functional assessment to be held in conjunction with
the International Rehabilitation Medicine Association's annual meeting.
UB has been in the forefront of medical rehabilitation for the past decade.
UB researchers have led a national effort
to develop the Uniform Data System for
Medical Rehabilitation that includes the
Functional Assessment Measure - a
standard now employed nationally and
internationally by facilities treating severely disabled people to define ability
to perform common tasks.
UB's department of rehabilitation
medicine also established a national
database that currently holds more than
400,000 patient records.
Byron Hamilton, M.D., clinical associate professor of rehabilitation medicine, is principal investigator on the
grant. Nadine Fisher, Ed.D., clinical assistant professor, is program coordinator and james A. Phillips, clinical instructor, is fiscal manager.
The new research and training center
will function within the framework of the
UB Center on Functional Assessment
Research, directed by Carl Granger, M.D.,
professor of rehabilitation medicine. +
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ichael Msall , M.D. , associate professor of pediatrics and rehabilitation medicine, has been elected
to membership in the Society for
Pediatric Research. Membership
in the national organization is
based on research record, sponsorship
by members in one's specialty area and
a vote by the full membership.
Msall's research has focused on the
problems and consequences of extreme
prematurity and functional independence in children with Down 's
syndrome, cerebral palsy and neurodevelopmental disabilities.
His work was published recently in
Clinical Pediatrics and appeared in the
February issue of the journal of
Perinatology.
+

• Apple • IBM • Dell •
Insight • Panasonic • Canon
• TI • Software • Supplies •
Accessories • Audio •
Hands-on Workshops

ATeam Effort -In March, New York
State Assemblyman Sam Hoyt presented
Dean Naughton with the pen Governor
Mario Cuomo used to execute legislation
Hoyt co-sponsored that enabled the
University Medical Practice Services to be
classified as not-for-profit, and therefore,
tax-exempt in New York State.

lml ,Dllltlri
A non-profit University program for students. faculty &amp;
The Commons • North Campus • (7 16) 645 -3554 • Fa x:

AKER

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�THEN&amp;IiiiiNOW

Traditions and training varied for first med students
TWO LECTURE COURSES REQUIRED FOR GRADUATION FROM FIRST CLASS OF
UNIVERSITY OF BUFFALO SCHOOL OF MEDICINE

• '

first medical students
differed from their
counterparts of today in
just about every way:
I
their demographics ,
._
1i
their age , their premedical school training and their medical school training.
Sixty-seven students comprised the
first class of the University of Buffalo
School of Medicine. Students then were
required to be at least 15 years old,
although the majority of the class were
18 to 21. All 67 students were white
males and many were already apprenticed to a "competent physician licensed
by a county medical society." Three
years of such apprenticeship were required before the degree of doctor of
medicine was awarded.
Like students now, students then paid
fees-$2 for matriculation, $5 for graduation and $10 each to six of the seven
professors who gave lectures or demonstrations. The professor of chemistry
was paid $12 from each student because
they used his equipment.
But unlike today, UB had "no provision for gratuitous aid" - no scholarships.
The school's first classes were held in
a wooden building (formerly the First
Baptist Church) on the corner of Seneca
and Washington Streets in downtown
Buffalo. Sold by the church in 1836, the
building was used successively since
then as a customs house, post office and
police court.
The university paid $700 to renovate
the church for its use. The yearly rent
came to $300. A library of 519 volumes

~

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The school's first
classes were held in
a wooden building
(formerly the First
Baptist Church) on
the corner of Seneca
and Washington
Streets in downtown
Buffalo.
was valued at $829.96; its museum of
anatomical, pathological and surgical
preparations and drawings cost $250.
An amphitheater accommodated 200.
Instruction nearly 150 years ago was
primarily by "lectures, demonstrations ,
clinical illustrations and recitations."
Students weren't required to take notes ,
but that method of learning was highly
recommended.
Lecture courses lasted 16 weeks. Two
such courses were required for graduation. Students often audited the same
course twice.
Most clinical experience was gained
through apprenticeships in the dispensary of the school and the county

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�THENI!IiEIN 0 W

..............................

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.----on
..._

free to indigent patients and others willing to be observed by students.
Students were allowed into the wards
of the almshouse at no charge "at such
hour of each day as the several medical
officers are in attendance."
And students then not only had to
meet the school's academic standards,
they had to be "of good moral character"
to qualify for a diploma. The council of
the university's first report to the Regents of the State of New York notes that
the faculty can "exercise the power of
expulsion for crimes of immoral conduct." But, it added, "no occasion for
the exercise of this power occurred during the last year."
Three weeks before the close of the
lecture term, students in the university's
first class delivered to the dean or registrar a dissertation "on some medical
subject which must be examined and
approved by the faculty previous to the
examination for the degree" before they
could receive their diplomas.
Diplomas then were licenses to practice. It was required, however, that they
were deposited on file with the Erie
County Clerk.
Specialists, of course, didn't exist
nearly 150 years ago and most students
set up their own offices or went into
joint practice with an older, experienced
physician. Surgery then was confined
largely to emergency procedures.
In his centennial address in 1946,
George W. Thorn, M.D., a UB alumnus, pointed out that 100 years earlier
only seven specific medications existed for disease - digitalis or foxglove for heart disease, quinine for
malaria, cowpox vaccination for smallpox, vermifuges for intestinal parasites, mercury for syphilis, iron for
hypochromic anemia and iodine, which
had proved important in preventing
goiter.
+

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···················· · ······ · · · ········· · ········· · ···· ·· ···· ·· · · ·· · ······· · ····· · ·· · ··· ·
.

I

Francis P. Alcedo , Internal Medicine, Yale-New
Haven Hospital, New Haven, Connecticut

Class of '94 wins big in Match Day

Robin] . Arent, Pediatrics, Eastern Virginia
Graduate School of Medicine, Norfolk, Virginia

87 PERCENT OF US'S GRADUATING MEDICAL SCHOOL

Kenneth] . Baker , Obstetrics and Gynecology,
St. Barnabas Medical Center, Livingston, New
jersey

SENIORS GET ONE OF THEIR FIRST THREE CHOICES

Daniel] . Barbero, Medicine/Pediatrics, Ohio
State University Hospitals, Columbus, Ohio

raduating seniors from UB's medical school fared well in this year's national
match for residencies.
A full 87 percent of the students who participated in the program were
matched with one of their first three choices for residency programs, and 67
percent of them got their first choice, according to Dennis Nadler, associate
dean for curricular and academic affairs.
Forty-four percent of the class will pursue a residency in one of the primary care
specialties: 10 in family practice, 32 in internal medicine, 18 in pediatrics and seven
in combined medicine/pediatrics.
Thirty-four percent of UB's graduating seniors will stay in the Buffalo area and
14 percent will remain elsewhere in the state to pursue their residencies. Fifty-two
percent will pursue residencies out of state.
Following is a list of students from the Class of '94 and their matches.
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Chad L. Beatty, Surgery (Prelim), University at
Buffalo Graduate Medical Dental Consortium
Martha I. Bennett, Family Practice, University
Hospitals of Cleveland, Cleveland, Ohio
Paula A. Bennett, Family Practice, University of
Maryland-Baltimore, Baltimore, Maryland
Jennifer J . Bergoine, Pathology, Medical College
of Virginia, Richmond, Virginia
Antonio M. Bird, Psychiatry, University of
North Carolina Hospital, Chapel Hill, North
Carolina
Joel S. Brenner, Pediatrics, Eastern Virginia
Graduate School of Medicine, Norfo lk, Virginia

G

Brian P. Brett, Medicine/Pediatrics , Morristown
Memorial Hospital , Morristown , New jersey
Tracy L. Brobyn, Family Practice, Mountainside
Hospital , Verona, New jersey
Daphine A. Brown, Internal Medicine,
Oakwood Hospital , Dearborn, Michigan
Gregory M. Bugaj , Internal Medicine, Mt. Zion
Medical Center of the University of California at
San Francisco, San Francisco, California
Thomas M. Burnette, Internal Medicine,
University Health Center-Pittsburgh, Pittsburgh,
Pennsylvania
Enrico Caiola, Medicine/Pediatrics, Baystate
Medical Center, Springfield, Massachusetts
Maria T. Cartagena, Surgery (Prelim),
University at Buffalo Graduate Medical Dental
Consortium, Uro logy, University at Buffalo
Graduate Medical Dental Consortium
William L. Cecere, Surgery (Prelim), University
at Buffalo Graduate Medical Denta l Consortium
james F. Chmiel, Surgery (Prelim), University
Hospitals of Cleveland, Cleveland, Ohio
Scott P. Cholewinski, Internal Medicine
(Preli m), University at Buffalo Graduate Medical
Denta l Consortium , Radiology - Diagnostic,
Strong Memorial Hospital, Rochester, New York

James Chmiel is congratulated by assistant dean Frank Schimpfhauser.

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�................................

Below, Charles Rocci looks on as Christian DeFazio
and his fiancee, Elizabeth Olson, open his match.
Left, DeFazio, who will study emergency medicine
at the University of Illinois, is congratulated by
Olson and
Falsone.

Dennis B. Chugh, Internal Medicine, St.
joseph's Hospital and Medical Center, Phoenix,
Arizona
Lynn M. Cieslak, Internal Medicine, St. joseph's
Hospital and Medical Center, Phoenix, Arizona
Kelli A. Cooney, Pediatrics, All Children's
Hospital, St. Petersburg, Florida
Devin A. Coppola, Family Practice, St. joseph's
Hospital Health Center, Syracuse, New York
Edwardj. Cosgrove, Internal Medicine
University at Buffalo Graduate Medical ~ental
Consortium
Kirsta Leale Craig, Family Practice, Southside
Hospital, Bay Shore, New York
Joseph P. Cronin, Medicine/Pediatrics
University at Buffalo Graduate Medical,Dental
Consortium
Ketan C. Dave, Surgery, Providence Hospital,
Southfield, Michigan
Maria L. Davis, Emergency Medicine, HarborUniversity of California at Los Angeles Medical
Center, Los Angeles, California
Christian R. DeFazio, Emergency Medicine,
University of Illinois College of Medicine at
Chicago, Chicago, Illinois

Glen T. Feltham, Orthopaedic Surgery,
University Hospitals of Cleveland, Cleveland,

Tracey I. Demino, Surgery (Prelim), North
Shore University Hospital, Manhasset, New York

Ohio

Nita K. Divan, Physical Medicine and
Rehabilitation, University at Buffalo Graduate
Medical Dental Consortium

Amy E. Ferry, Obstetrics and Gynecology, St.
Luke's Hospital of Bethlehem, Bethlehem,
Pennsylvania

Todd A. Dorfman, Surgery, Maine Medical

Sarah G. Finnegan-Sloan, Internal Medicine
(Prelim) , University at Buffalo Graduate Medical
Dental Consortium, Neurology, University at
Buffalo Graduate Medical Dental Consortium

Center, Portland, Maine
Winston G. Douglas, Internal Medicine,
University at Buffalo Graduate Medical Dental

Consortium
Mark D. Fisher, Internal Medicine (Prelim),
University at Buffalo Graduate Medical Dental
Consortium , Anesthesiology, University at Buffalo
Graduate Medical Dental Consortium

Brian C. Dowdell, Internal Medicine (Prelim),
Sisters of Charity Hospital, Buffalo, New York,
Physical Medicine and Rehabilitation, Stanford
University Hospital, Palo Alto, California

Lorna K. Fitzpatrick, Pediatrics, St. Louis
Children's Hospital at Washington University
Medical Center, St. Louis, Missouri

john L. D'Souza, Internal Medicine (Preli m),
Strong Memorial Hospital, Rochester, New York,
Radiology- Diagnostic, Rochester General

David S. Foley, Surgery, Bowman Gray School
of Medicine/North Carolina Baptist Hospital,
Winston-Salem, North Carolina

Hospital, Rochester, New York
Darlene A. Durkin, Pediatrics, University at
Buffalo Graduate Medica l Dental Consortium

Maura P. Foley, Internal Medicine, University of
Virginia, Charlottesville, Virginia

joseph M. Falsone, Internal Medicine,
University at Buffalo Graduate Medical Dental

Deborah L. Delozier, Obstetrics and
Gynecology, Strong Memorial Hospital,
Rochester, New York

Patricia A. Geil, Pediatrics, University at
Buffalo Graduate Medical Dental Consortium

Consortium
Maureen A. Fay, Internal Medicine, University
of Connecticut, Farmington, Connecticut

Petros Ghermay, Psychiatry, University of
California at San Francisco, Fresno, California

Gloria M. del Valle, Pediatrics, University at
Buffalo Graduate Medical Dental Consortium

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�Michael T. Giovanniello, Physical Medicine

Presbyterian-St. Luke's Medical Center, Denver,

Albany Medical Center Hospital , Albany, New

and Rehabilitation, Ohio State University

Colorado, Radiology- Diagnostic, University of

York , Radiology- Diagnostic, Albany Medical

Hospitals , Columbus, Ohio

Co lorado, School of Medicine, Denver, Colorado

Center Hospital , Albany, New York

Douglas J. Golding, Family Practice, University

Horacio Gutierrez, Internal Medicine (Prelim),

Diane R. Heimback Morrison, Obstetrics and

at Buffalo Graduate Medical Dental Consortium

Sisters of Charity Hospital, Buffalo, New York,
Radiology - Diagnostic, University of Colorado

Gynecology, University at Buffalo Graduate

Mabel P. Gong, Obstetrics and Gynecology, New

Medical Dental Consortium

School of Medicine, Denver, Colorado

York Downtown Hospital , New York, New York

Idalia M. Gonzalez, Pediatrics, University at
Buffalo Graduate Medical Dental Consortium

james D. Gould, Internal Medicine (Pre lim),

Geoffrey G. Hobika , Internal Medicine,

Sandra M. Gutierrez, Surgery , The Brooklyn

University at Buffalo Graduate Medical Dental

Hospital Center, Brooklyn, New York

Consortium

George E. Haddad , Internal Medicine,

Karen L. Houck, Obstetrics and Gynecology,

University at Buffalo Graduate Medical Dental
Consortium, Anesthesiology, Duke University

University at Buffalo Graduate Medical Dental

University at Buffalo Graduate Medical Dental

Consortium

Consortium

Medical Center, Durham, North Carolina

Tegest F. Hailu, Family Practice, University of

Carline T. Hyppolite, Internal Medicine

Theodore S. Grabow, Transitional Year,

California at San Francisco, Fresno, California

(Prelim), North Shore University Hospital,
Manhasset, New York

Hennepin County Medical Center, Minneapolis,
Minnesota, Anesthesiology, The University of

Medical Center of Eastern Carolina, Greenville,

Patricia E. Allen Iheke, Obstetrics and

Chicago Hospitals, Chicago, Illinois

North Ca roli na

Gynecology, University at Buffalo Graduate

Kim S. Griswold , Family Practice, University at

Christian H. Hansen, Pathology, Georgetown

Buffalo G raduate Medical Dental Consortium

University Hospital, Washington, D.C.

Geoffrey M. Gullo, Tra nsitional Year,

George]. Hatsios, Interna l Medicine (Pre lim),

Steven D. Hammel, Pediatrics, University

Medical Dental Consorti um

Gregory T. jehrio, Internal Medicine, Mary
Imogene Bassett Hospital, Cooperstown , New
York

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�.. . ...... . . .. .... . . . ..... . .. .. . . ...... . . .. ..... . ... .. .. . . . .. . . . ....... . ... . ...... . ...

•

~

Above, Todd Schlesinger, left, and Atif Zafar get
the good news. At left, Charles Rocci, Stephen
Machnicki, Michael Giovaniello, Joseph Falsone
and Glen Feltham celebrate.
Andrew D. jenis, Surgery, University at Buffalo
Graduate Medical Dental Consortium
Jeffrey W . Kanski, Internal Medicine (Prelim),
Roger Williams Hospital, Providence, Rhode
Island
Joseph D. Kay, Medicine/Pediatrics, University
of Michigan Hospitals, Ann Arbor, Michigan
Barbara P. Kearney, Pathology, University at
Buffalo Graduate Medical Dental Consortium
Glenn E. Kershen, Surgery (Prelim), Temple
University Hospital, Philadelphia, Pennsylvania,
Urology, Temple University, Philadelphia,
Pennsylvania
Carol Ann Killian, Emergency Medicine,
University Health Center of Pittsburgh,
Pittsburgh, Pennsylvania
Richardj . Kozak, Emergency Medicine, Oregon
Health Sciences University , Portland, Oregon
Michaelj . Krabak, Internal Medicine, Barnes
Hospital, St. Louis, Missouri
David G. Kupkowski, Internal Medicine,
United States Naval Medical Center, Portsmouth,
Virginia
Michael K. Landi, Surgery (Prelim), University
at Buffalo Graduate Medical Dental Consortium ,
Neurological Surgery , University at Buffalo
Graduate Medical Dental Consortium
Timothy J. Larosa, Psychiatry, University
Hospitals of Cleveland, Cleveland, Ohio
Christian D. Lates, Pathology, University at
Buffalo Graduate Medical Dental Consortium

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janet M. Lawrence, Medicine/Pediatrics,
University at Buffalo Graduate Medical Dental

Lauraj. Nicholson, Internal Medicine, Strong
Memorial Hospital, Rochester, New York

Consortium
Paulj . Lee, Internal Medicine, Albert Einstein
Affiliated Hospitals, Bronx, New York

Michael P. O'Neill, Radiology- Diagnostic,
University of South Florida College of Medicine,
Tampa, Florida

Wendy L. Leffel, Family Practice, Forbes Health
System , Pittsburgh, Pennsylvania

juliana S. Paik, Pediatrics, University of
California at San Fra ncisco, Fresno, California

Chien H. Lin , Surgery, Nassau County Medical
Center, East Meadow, New York

Michaelj. Pelechaty, Jr. , Internal Medicine,
Guthrie Healthcare System/Robert Packer
Hospital, Sayre, Pennsylvania

Stephen C. Machnicki, Internal Medicine
(Prelim) , Winthrop-University Hospital, Mineola ,
New York, Radiology- Diagnostic, Lenox Hill
Hospital , New York, New York

Michelle D. Penque, Pediatrics, University at
Buffalo Graduate Medical Dental Consortium
Sean Perini, Internal Medicine (Prelim),
University of Washington, Seattle, Was hington,
Radiology - Diagnostic, University of California
at San Francisco, San Francisco, California

Andres M. Madissoo , Surgery (Prelim) ,
University at Buffalo Graduate Medical Dental
Consortium , Urology , University at Buffalo
Graduate Medical Dental Consortium

Richard G. Pinckney, Internal Medicine,
Medical Center Hospital of Vermont, Burlington,

Stacey A. Madoff, Obstetrics and Gynecology,
George Washington University, Washington, D.C.

Vermont
john Pollina, Surgery , University at Buffa lo
Graduate Medical Dental Consorti um

Rita M. Malvaso , Internal Medicine (Prelim) ,
Baylor University Medical Center, Dallas, Texas,
Physical Medicine and Rehabilitation, University
of Texas Southwestern Medical School , Dallas,

Ulka Prakash, Internal Medici ne (Prelim),
University of Mary land School of Medicine,
Baltimore, Mary land, Anesthesiology, johns
Hopkins Hospital , Baltimore, Mary land

Texas
Frankj . Mascaro, Internal Medicine, University
at Buffalo Graduate Medical Dental Consortium

john Pryor, Surgery, University at Buffa lo
Graduate Medical Dental Consorti um

john R. McArdle, Internal Medicine, Yale-New
Haven Hospital , New Haven, Connecticut

Nasser Razack, Surgery (Preli m), No rth Shore
University Hospita l, Manhasset , New York

Elizabeth A. McClintick, Internal Medicine
(Prelim), University at Buffalo Graduate Medical
Dental Consortium , Anesthesiology, University at
Buffalo Graduate Medical Dental Consortium

Edward D. Reidy, Internal Medici ne (Preli m),
Sisters of Charity Hospital, Physical Medicine
and Rehabilitation , New England Med ical Center,
Boston, Massachusetts

Lisa L. Miller, Pediatrics, Rhode Is land Hospital ,

Providence, Rhode Island
Stephanie C. Mitchell, Internal Medicine,
Overlook Hospital, Summit, New jersey

Cindy D. Repicci, Physical Medicine and
Rehabili tation, Univers ity at Buffalo Graduate
Medical Dental Consortium

Paulj . Mus tacchia, Internal Medicine (Prelim),
Presbyterian Hospital, New York, New York

Charles A. Rocci, Emergency Medici ne, Albany
Medical Center Hospi tal, Albany, New York

Erns t Nanor, Internal Medicine (Preli m),
Norwalk Hospital , Norwalk , Connecticut,
Anesthesiology, Tula ne University School of
Medicine, New Orleans, Louisiana

Thomas Romanelli, Internal Medici ne (Preli m),
University Hospitals, SUNY at Stony Brook,
Stony Brook, New York , Anesthesio logy,
University at Buffalo Graduate Medical Dental
Consortium

Michael A. Nasiak, Internal Medicine,
University at Buffalo Graduate Medica l Dental

Consortium

Paul J. Sagerman, Pediatrics, St. joseph's
Hospital, Phoenix, Arizona

Tung V. Nguyen, Internal Medicine, Kaiser
Foundation Hospital, San Francisco, California

Diana R. Sanderson, Psychiatry, University at
Buffa lo Graduate Medical Denta l Conso rtium

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~

I

jennifer M. Thompson, Obstetrics and
Gynecology,]ersey Shore Medical Center,
Neptune, New jersey
Gregory V. Tobias, Internal Medicine (Prelim),
University at Buffalo Graduate Medical Dental
Consortium, Anesthesiology, University at Buffalo
Graduate Medical Dental Consortium
Madonna R. Tomani, Obstetrics and
Gynecology, University at Buffalo Graduate
Medical Dental Consortium
jennifer M. Tufariello, Obstetrics and
Gynecology, Ohio State University Hospitals,
Columbus, Ohio
joseph S. Valenti, Obstetrics and Gynecology,
University at Buffalo Graduate Medical Dental
Consortium
Yvette M. Vinson, Surgery (Prelim), Strong
Memorial Hospital, Rochester, New York,
Otolaryngology, University of Rochester,
Rochester, New York

From left, Carhne Hyppohte, Paula Bennett, Andrea Withams, Gloria Del Valle, Jennifer Thompson and
Patrida lheke share their joy.
Pina C. Sanelli, Anesthesiology, Albany Medical
Center Hospitals, Albany, New York

james W. Spain, Radiology -Diagnostic,
Milton S. Hershey Medical Center of
Pennsylvania State University, Hershey,
Pennsylvania

Paul Sansone, Internal Medicine, DartmouthHitchcock Medical Center, Lebanon, New
Hampshire

Michael Stanton, Internal Medicine, University
of Michigan Hospitals, Ann Arbor, Michigan,
Neurology, University of Michigan Hospitals, Ann
Arbor, Michigan

Mark W. Sheldon, Internal Medicine, Hospital
of the University of Pennsy lvania, Philadelphia,
Pennsy lvania

Donna M. Stawasz, Medicine/Pediatrics,
University at Buffalo Graduate Medical Dental
Consortium

john T. Sherwood, Internal Medicine, johns
Hopkins Hospital, Baltimore, Maryland
Donna G. Sinensky, Transitional, Mercy
Catholic Medical Center, Darby, Pennsy lvania,
Physical Medicine and Rehabilitation, New
England Medical Center, Boston, Massachusetts

Gregory H. Stiller, Surgery (Prelim), University
of Colorado School of Medicine, Denver, Colorado
Mary E. Stock, Internal Medicine, University at
Buffalo Graduate Medical Dental Consortium

Donald M. Slate, Pathology, University at
Buffalo Graduate Medical Dental Consortium
Sisters of Charity Hospital, Buffalo, New York,
Anesthesiology, McGaw Medical Center of
Northwestern University, Chicago, Illinois

Sharon A. Szukala, Pathology, Duke University
Medical Center, Durham, North Carolina

Wendy I. Snyder , Pediatrics, University at
Buffalo Graduate Medical Dental Consortium

Behzad Tabibian,Internal Medicine, CedarsSinai Medical Center, Los Angeles, California

Kenneth A. Sobel, Pediatrics, University at
Buffalo Graduate Medical Dental Consortium

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Amy L White, Pediatrics, University at Buffalo
Graduate Medical Dental Consortium

Andrea M. Williams, Surgery, University at
Buffalo Graduate Medical Dental Consortium
Douglas W. Wisor, Transitional, Reading
Hospital and Medical Center, Reading,
Pennsylvania, Physical Medicine and
Rehabilitation, Medical College of Virginia,
Richmond, Virginia

Theodros Yohannes, Surgery, University of
Louisville School of Medicine, Louisville,
Kentucky, Urology, University of Louisville
School of Medicine, Louisville, Kentucky
Atif Zafar, Internal Medicine, University of

+

Cincinnati Hospital, Cincinnati, Ohio

Debra R. Tarantino, Surgery, University
Hospitals of Cleveland, Cleveland, Ohio

p

Christina G. Weston, Psychiatry, United States
Air Force Medical Center (Wright-Patterson),
Dayton, Ohio

Christopher F. Wood, Internal Medicine
(Prelim), Strong Memorial Hospital, Rochester,
New York, Ophthalmology, Loyola University
Hines VA Hospital, Maywood, Illinois

Thaddeus E. Szarzanowicz, Surgery (Prelim),
University at Buffalo Graduate Medical Dental
Consortium, Orthopaedic Surgery, University at
Buffalo Graduate Medical Dental Consortium

J. Paul Sla venas,Internal Medicine (Prelim),

u

jennifer C. Wargula, Pediatrics, University
Health Center of Pittsburgh, Pittsburgh,
Pennsylvania

Maya D. Srivastava, Pediatrics, Cleveland
Clinic Foundation, Cleveland, Ohio

Todd E. Schlesinger, Dermatology, Cleveland
Clinic Foundation, Cleveland, Ohio

B

lauren j . Vriesenga, Family Practice, Riverside
Regional Medical Center, Newport News,
Virginia

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11
'

is free from Boehringer
Ingelheim Pharmaceutical representatives. Dr. Bianco and his
wife, Joan, have a new addition,
Regina-Marie, born August 1,
1993. She joins David, 12, and
John-Michael, 8. "We're all fantastic!! "

tinguished Alumnus Award in
1989, received the award as part
of the Sixteenth Annual Meeting of the St. Louis Metropolitan Medical Society.

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was reelected treasurer of the Minnesota Medical Association last
September.
ERICK REESER '56,

MICHAEL A . SANSONE '73,

JOHN R . ANDERSON '57, was

Thomas F. Frawley '44
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gives seminars on "Living With Low Vision" as part of the Mariners
Hospital Community Lecture Series. Dr. White has low vision
and his experience provides the
visually impaired with techniques to increase their independence. His program includes
a presentation on closed caption
TV enlargers and talking books.
In March Dr. White received certificates of appreciation from
Florida's Department of Elder
Affairs and the Alliance for Aging for his volunteer service.

named medical director of the
Brothers of Mercy Nursing and
Rehabilitation Center, Clarence,
New York.

Frankhn Zeplowitz '58
by the Buffalo News in its 45th
Annual Awards for Outstanding
Community Service.

JOHN WHITE '40,

THOMAS F. FRAWLEY '44,

chairman of graduate medical
education at St. John's Mercy
Medical Center, St. Louis, Missouri, was awarded the Robert
E. Schlueter Award for "demonstrating excellence in clinical
practice, promoting advocacy for
patient care in socioeconomic
and political matters and for representing the medical profession
in community service." Dr.
Frawley, who received UB's Dis-

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FRANKLIN ZEPLOWITZ '58,

was elected chief of staff of Our
Lady of Victory Hospital, for
1994-96. He is an attending surgeon at the Lackawanna hospital and a past president of its
medical staff. He is a UB clinical
instructor of surgery.

1

9

6

1

HARVEY LIEBESKIND '63,

writes, "Hoping to retire this
year, move to California, travel
with my mate, buy and sell thoroughbred horses for a living.
My oldest son, Louis, trains
horses, middle son, Neil re-

•

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5

LAWRENCE ZEROLNICK '72,

atrics to join Kaiser Permanente
in Baltimore. He and his wife,
Barbara, announce the birth of
their son, Matthew, on November 8, 1993.
of
Washington, D.C. , just completed a book for patients with
arrhythmia entitled, You Can
Live With It! This 66-page book
ROBERT DIBIANCO '72,

cal director of Hospice Buffalo,
was named a Citizen of the Year

II

0

has left private practice in pedi-

ROBERT A. MILCH '68, medi-

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7

recently was honored by theN ew
York State Ophthalmological
Society for "leadership and commitment to organized ophthalmology in New York State." He
is a past president of the state
society and has been a member
of the Federal Economic Committee, which advises Medicare
on health-care reform. Sansone
is chairman of the New York
State Managed Care Committee.
JOHN KEYES '75, is secretary-

treasurer of the medical staff at
Lake Shore Hospital in Irving,
New York.
married attorney Carol Siravo in Cranston,
Rhode Island, in April.
ALAN PERL '77,

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s

JOSEPHT. WAYNE'82, is pro-

searches horse pedigrees, youngest son, Stuart, is a movie
stuntman and bartender. Lee
Baumel '63, moved to Hawaii in
1993. Paul Lessler '63 retired
and is doing financial consulting work."

p

9

MICHAEL BARON '71 , writes,
"I have recently had two positive events occur in my career
which I would like to share with
the Alumni. I received the
Inpatient Teacher-of-the-Year
Award, 1992-1993, from the
Family Practice Residency Program of the University of Massachusetts Medical Center. In addition, I am now a diplomate in
critical care medicine."

s

0

I

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gram director of the combined
internal medicine-pediatrics
training program at St. Louis
University. He announces the
birth of his son, Gregory Joseph,
on January 9 , 1994.
HERBERT NEWTON '84, is
assistant professor of neurology
and director of the division of
neuro-oncology, Department of
Neurology at Ohio State University Medical Center.

9

9

4

�•

······· · ······ · ··· · · · ···· · ··· · ···· ··· ············ ··· ··············· · ···· · ···· ·· ···· · ······

I

my general surgery internship
in Denver, I spent two years as a
brigade surgeon at Ft. Bragg,
North Carolina, 82nd Airborne
Division. We moved back to
Buffalo,july 1993, at which time
I started my orthopaedic residency. I married Anita Pantera
in August 1991. We were introduced by our fellow classmate
Virginia Beerel Campion '90.
She and my wife went to high
school together. We have two
beautiful sons, Ryan Douglas,
20 months, and Connor Matthew, 6 months.

MICHAELS. WATSON'87,an
anesthesiologist, is vice president of the medical staff at Lake
Shore Hospital in Irving, New
York.

Brian Moore Bernard
ROBIN CONWIT '85, has
moved to Baltimore and is now
an assistant professor at johns
Hopkins and director of the EMG
Lab at the Francis Scott Key
Medical Center.
MICHAEL SANSANO JR. '85,
has opened his own practice in
ophthalmology at 515 Abbott
Road, Buffalo, New York. He and
his wife, Claudia, have four
daughters.

HELEN CAPPUCCINO '88, has
opened an office in Lockport,
New York for the practice of general, thoracic and laparo-scopic
surgery. Andrew Cappuccino '88,
is completing a spine fellowship
with Paul McAfee at johns
Hopkins and will be practicing
in Amherst and Lockport injuly.
The Cappuccinos are the proud
parents of four children:
Jacqueline, 13; Mac, 5;jake, 2;
and Nicholas, 1.

M

DAVID I. KOLE '90, of Santa
Maria, California is in private prac-

tice and is chief of pediatrics at
DAVID R. BLOOM '89, is now
a partner of Beach Physicians
and Surgeons Medical Group,
Inc., Huntington Beach, California. He is also the team physician at Orange Coast College.
"Doug Sillart '89, is a travelling anesthesiologist extraordinaire.

Marian Medical Center. He has two

children, Ben, 6, and Emily, 4.

KRISTA M. (PRIGG) KOZACKI
'91 of Florence, South Carolina, is finishing a family medicine residency in 1994 and is
considering private practice or
a faculty position opportunity.
She is the recipient of the
McLeod Regional Medical Center Merit Award. Her twin sons,
Stefan jerome and jacob Scott,
were born on February 18, 1993.

M

DONNICA L. MOORE '86, and
her husband, Stan Bernard, M.D.,
M.B.A., are delighted to announce the birth of their son,
Brian Moore Bernard, on Labor
Day, 1993. As is obvious from
this photo, he is eager to follow
in Mommy's and Daddy's footsteps, although with the directions their careers have takenDonnica is associate director,
professional relations at Sandoz
Pharmaceuticals and Stan is director, pharmacoeconomics at
Bristol Myers Squibb Company
- a briefcase might be a more
appropriate prop!

B

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5

MARK A. FLANZENBAUM '90,
is completing a residency in
combined internal medicine and
pediatrics at the Medical College ofVirginia. He has accepted
a position as attending physician in emergency medicine
beginning in August 1994.
Flanzenbaum is engaged to be
married inN ovember to Christie
R. Boyd, a neonatal intensive
care nurse at the Medical College of Virginia.

RICHARD G. BENNETT '92,
is a second-year psychiatry resident at Case Western University Hospitals. He married
Dawna Lynch on july 9, 1993.

p

h

II

•

CURZON CADY FERRIS, JR .
'46, died in july, 1993. He was
71 years old. Dr. Ferris retired
from the Hendrick Medical Center in Abilene, Texas, in 1988.
LINDA SHRIRO SCHENCK
'77, an adjunct professor at the
University of Minnesota's
School of Public Health, died of
complications from an autoimmune disease in December 1993.
ESTER MARIE PONCE
GRIMALDI '89, was killed on
January 18, 1994, when the car
she was driving hit a patch of
ice, and slid over an embankment. She was six months pregnant with her second child. Dr.
Grimaldi had just completed her
residency in pediatrics and was
working for a health maintenance organization in Michigan.
Besides her husband Thomas
Grimaldi '89, she is survived by
her daughter, Sarah Marie.

Buffalo Physician Goes Electronic

Now you use the Internet to
send classnotes or other
information to Buffalo
Physician. Our address is:

OBITUARIES

HOWARD CRAIG KEYES '28,
died in Bellingham, Washington, July 8, 1993, three days
short of his ninetieth birthday.
Until his retirement in 1974,

DoUGLAS PATRICK PREVOST
'90, writes, "After completing

a

Dr. Keyes practiced at the Keyes
Clinic, consisting of a father and
three sons, all of whom graduated from the University of Buffalo Medical School- William
Chauncey Keyes in 1896,
Roswell Park Keyes in 1926 and
Donald Keyes in 1928.

c

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Notes@pub.buffalo.edu
We'd love to hear from you
via e-mail or snail mail!

m

e

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4

��BUFFALO PHYSICIAN
STATE UNIVERSITY OF NEW YORK AT BUFFALO
3435 MAIN STREET
BUFFALO NEW YORK 14214

2194

ADDRESS CORRECTION REQUESTED

ME DICAL HISTORICAL LI 3RARY
ABBOTT LI BRARY SERIALS DEPT
CA PUS MAil.

The only liability coverage
with this seal of approval.
Medical Liability Mutual Insurance
Company (MLMIC) is the only professional
liability insurer approved by the Medical
Society of the State of New York.
Since its founding in 1975, the physicianowned and managed company has successfully defended more physicians than all
other available insurers combined.
Additionally, MLMIC has the largest
and most experienced professional liability claims department in the country, the
largest risk management department of
any New York State professional liability
insurer, and the state's only true peer
review of claims experience.
Call1-800-ASK-MLMIC (metro) or
1-800-356-4056 (upstate) for more information and an application.

MLM~C
~
Medical liability
Mutual Insurance Company

Our defense never rests.
2 Park Ave., New York, NY 10016
2 Clinton Sq., Syracuse, NY 13202
90 Merrick Ave., East Meadow, NY 11554

«:&gt; 1993 Medical liability Mutual Insurance Company

Non-Profit Org.
U.S. Postage
PAID
Buffalo, NY
Permit No. 311

�</text>
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                    <text>State University of New York at Buffalo School of Medicine and Biomedical Sciences, Autumn 1994

UB'S FACULTY PRACTICE MANAGEMENT PLAN MAKES SENSE FOR ITS FACULTY MEMBERS AND
THE PATIENTS AND STU DENTS THEY SERVE

�BUFFALO PHYSICIAN

Dear Alumni and Friends,

\olume .!8, \iumber 4

T

ASSOCIATE VICE
PRESIDENT FOR
UNIVERSITY
ADVANCEMENT

Dr C" ole ~m!lh Petro
DIRECTOR OF
PUBLICATIONS

flmothv ). C mwv
EDITOR

..1ne·te

Ird.:-::.c~,:

R l\1

ART DIRECTOR
Ala,., I. Kcglr•
ASSOCIATE ART DIRECTOR

xonl

rl(l

er

PRODUCTION MANAGER
Ann R~\slm~mn Br..&gt;wn
STATE UNIVERSITY OF
NEW YORK AT BUFFALO
SCHOOL OF MEDICINE
AND BIOMEDICAL
SCIENCES
l'r 'vim aug; t.m. V 1ce Presd•nt
for C •• meal Affd: cs. Dean
EDITORIAL BOARD
Dr john \ Riche t l h~"nn"
Dr Russell \\ Bessette
Dr \hnm Bul.bc:
Dr ll n ld D:--)c.h·

Dr
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Dr
Dr
Dr
Dr
Dr
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Rich.:d L ( .Ji ms
Ra' i DrsJi
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l.tmes Kntskt
~I 1zabet h Olmsted
Ll·arlrs Pa~•. clli
i ho"'as Ra.;~

hts tssuc of Buffalo Phvstcian reviews t\vO activllies of singular importance ~o L B\
medical ~chool- the proposed Academic Medtcal ( ollegmm and the lOth ann!\ ersarv of the operation vf the ~Lhool sF acuhy Practice Management Plan (F PMP, The
latter was m:mdated b) the state legtslature to ensure that full-time and geographical
full time chmca: faculty members met &lt;.ducauonal and research responsibtliues to Slt Y
,md to dewlop a mechanism to employ talented fa&lt;.ult) at competiuve compensatwn :evels.
Such organizations are alwavs dtfficult to implement, It IL'ok t.B
almost l 0) ears to wmplv with the legislauve in illative and the '&gt;l ''t
Trustees" pohc1es. But the FP\IIP has proven its potenual to cement the
tnstltutional rclauon'&gt;hip of a clmi...a' fa&lt;.ulty dispersed throughout
\\estern "\e\\ York The 1991 audn mdkates this decentralized plan
ts functionmg well Of a tot.1l revenue ha'&gt;t of approximately $70
mtlhon, almost half went 10 support f&lt;~cult\ sala!"ics and $2 9 millio~t
.md '&gt;2.7 mil11on respeLt:\el) \\tre returned to the hospitals for overhead and to the school for academtc program developrrent.
The \cad(:m1c MedKal (ollegmm represents a broader umverSil\ -cL&gt;mmunlt) effort to mvolve the school, tea&lt;.hiPg hospllals, cimical fac ultv ,md
hospital ph\ st.:ian staffs m more cooper&lt;~ the plannmg and work .ts the needs to meet the
extgcnnes related to health care an&lt;l medt&lt;.al edu&lt;.atlon reform becomt reality fhts
orgamzatwn 1s working to defme its prmuples of orgamzation and w tll follow"' tth more
speulk orgamzatlonal planmng. Gtvtn the su&lt;.cec;s ol some ol l B sand the community s
&lt;.on~orual expenenees. this new c&gt;rgamzauon could lorm a model from whkh !le\\
c:ooperatl\ e ventures de\ clop m \Ve'itern "le\\ 'r ork, and on-.e o.~g.:~in, .tn orgamzauon that
wuld sene as a model for those vther aL.:~demicallv onented medtcal&lt;vmmunmes that
are struggling to deal with the c..omplex tssuec, of health care ard health edu&lt;.ation refvrm.
Smcerd),

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T ; r ax

john "\aughton, \1.0.
for Chmull \jfa:r~
Own ';c hool of \Jcdrcinr and Biomedtcal -'&gt;ucnLn
\'1&lt; c Prc~ident

TEACHING HOSPITALS AND
LIAISONS
fhc r 1iliO (.Je""IC'r"-. Hospll.ll
\fi, had ~haw

Buffa!&lt;'\\ Vdi"" Center

Dear Fellow Alumni,

\~knr kt!~v

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The U1: ld:e:o s H•&gt;Si&gt;" !I of Buff.
Ene Cvuntr ''~dh.~. Ccntc·
"'er,) H"s"l:-Jl
~!tllarJ f til more llospuals

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qu:~rtc1~y b,· thr ..,Ute l nh~ r;:'"' ·&gt;f
!'.rw )ctk Jt Bulf.,Io School ct
\1c&lt;i.~ont:: anti F10medacal &lt;;ocf\C("S
and the Ltft h r ef i 'uf"'.l,cJtlons. h

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SLnt free vi (hargc w.Ilumni, :.tt ultv
Stude:1h, Tt.:.SilkntS .md fn·~"nJs. fhc
5taP rescn.ec;. the nJI'-t t.)edatall ... op)
Jnd SlibtnJSstons a.ccpteJ fc.r

publa.. Jta_ 11
\ddrcc;s q:~C"&gt;Ilons, ~o..cmmc~lh and
s.ubmiSS~&lt;)nS to:
[d .. tor L:uf(ult,
Ph)'')tl~un, ")LJ.tc l mvcrsuy of "l'"w

)c•rk Jl Buflalo
L'nl\crsttv
PuhlcJtHll:S.I ~{&gt;( r.·'t,llJll,U;.:!IJ:u.
"'cv. )Jrk 142o(' orb~ .•. r-o~JI Jt
notesu-'; &gt;t: h. bu ff~lo.eue&gt;.

Send address &lt;hanges to:

flu/Jul.•

Ph}llc&gt;an. 14 ( l"&gt; \ddittc•o

l41j

Mam ~t: ec! f.uffJic· "'cw h·rk d 2 I I

our alumni board recently held tb mtd-&lt;.ummer me~ting ..1nd pLm&lt;. are well
undt:rwav for the upLc'mt.ng medical &lt;&gt;chool year \Vekommg rec ~puons were held
for !re'ihm.m and junior students ro1l0w mg form:d pre&lt;;entaticms, the \lumm
\s.,ouauon sponsort:d a c;octal event for stud~n•s
I he SULLC~sful &lt; ommumty Phv-.toans' Progr.tm w 11l be contmued fhe \t:Jr&lt;. aclt\ 1·
ues, '' hKh mclude mtroducing &lt;&gt;tudents to the dJtl) praw,e ol d1ffermt mediul-.peualt.e'&gt;.
'' :P be &lt;.o-&lt;.haired bv Dr&lt;;. Roger Daver 'oO, .tnd Beth \tah.:r '85.
fhe board arranged for the p""esident of the Mcdicai "&gt;tudent Pol:t) h.&gt;
.:mend se\er.tl mectmgs, allowing for mort .:arrfulh C\aluated requesb
and opponunitt.:s forLooperauon betwet:n the student bod\ and A.lumm
AssL'Uatwn
Plans for '&gt;pnng (. hmcal Da) and Reumon Weektnd ,tre begmnmg
to sohdify under the dtre.:tk&gt;n of c hJtrperson Dr. j.:~ck ( m ne 8) ln
'&gt;epttmbu, \\ e pre~ented the D snnguished \kdical J\lumnus A'' ard
to Dr '\Joel Rose '64 Hts achtevementc, are -nHmati&lt;'nalh recognized: 11 IS an honor to have pre.,ented thts award to him
ln'-.: ,tgain 'our '\lumm Assocuuon seeks to provide \\ays to a&lt;.si&lt;.t bt&gt;th th nc.:nt
and &lt;ocnivr members. II you ha\ e &lt;IllY 1dea&lt;. that' ou \Hsh to sh..1re, plea~c d~' not hestt.tte
to LOntact me
Smcerelv.

~
c:::::

Russell \V Be&lt;;~ette, D D '&gt;, \1 D. '76
P,-esrdmt, \lcdical Alumm As~L'&lt; iatwn

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Where's the beef?
Page 2.

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Research
Hospital News
Practice Makes Perfect e After 10 years, UB's
Faculty Practice Management Plan makes sense
for its faculty members and the patients and
students they serve.

m

Equal Time e The new Academic Medical Collegium

gives its members an equal say in the future of
health care in Buffalo.

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Medical School

Then and Now

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Alumni

Then and Now. Page 26.

ASpoonful of Humor

m

Classnotes

*

l~e new
~cafiemic

ffiefiical
[ollegium
ta~es s~a~e.

rage lt

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Roswell researchers arrest human
cancer xenograft in scid mice
B and Roswell Park Cancer Institute scientists have been able to
arrest the growth of human lung
cancer xenograft in severe combined immunodeficient (scid)
mice by administering a long-circulating liposome formulation of doxorubicin known as Doxil.
By doing so, Richard B. Bankert, Ph.D.,
D.V.M., associate research professor and
principal investigator on the study, and
colleagues, have reported the first direct evidence that antitumor drugs delivered in sterically stabilized liposomes
are more effective at halting the growth
of human tumors than more conventional systems. Bankert's research also
establishes the scid mouse as a viable
model in which to study novel chemotherapeutic approaches to treating human solid tumors.
"The scid mouse appears to be an
excellent model for in vivo testing the
activity of anticancer agents on solid
tumors due to its ability to produce
tumors that retain the histological characteristics and metastatic potential of
the original human specimen," Bankert
said.
Administering drugs in liposomes to
reduce toxicity and target the drug to
the tumor has been under investigation
at Roswell for 20 years. The effectiveness of conventionalliposome preparations has been limited by their brief
circulation time, as well as their susceptibility to uptake and clearance by the
liver and spleen, and the binding of
plasma components to their surface,
causing the liposomes to break down
and leak before reaching the tumor.
Bankert and his team used sterically
stabilized liposomes, which exhibit an
enhanced ability to accumulate within

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The fatty acid found in meats and dairy products may offer some protection against breast cancer.
solid tumors in vivo. The researchers investigated the antitumor effects of Doxil,
doxorubicin encapsulated in conventional
liposomes ( C-DOX) and free doxorubicin
against a human squamous cell carcinoma of the lung grown in scid mice.
"Doxil completely arrested tumor
growth in all of the mice tested , while
free doxorubicin only slightly delayed
tumor growth and C-DOX was ineffective at arresting tumor growth , although
some decrease in growth rate was observed," Bankert said.
Clinical trials for patients with lung
cancer res is tan t to first -line chemotherapy are underway.
+

Where'sthe beef?
esearchers at Roswell Park Cancer Institute have found that conjugated linoleic acid (CLA), a
minor fatty acid found preferentially in meats and dairy products , offers some protection
against breast cancer in animal models.
"Unlike most fatty acids , CLA prevents rather than stimulates cancer development," said Clement Ip, Ph.D., UB
assistant research professor from

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Roswell's division of breast surgery.
Meat from ruminants contains more
CLA than meat from other animals; bacteria from the ruminant's stomach can
convert linoleic acid, an essential polyunsaturated fat, into CLA.
"Dairy products and cheeses are also
good sources of CLA," explained Ip, whose
two recent studies provide strong evidence
of the fatty acid's anticancer properties.
Ip found that rats whose diets contained 0.1 percent CLA by weight - the
equivalent of about four times the amount
consumed in the everyday diet of the
typical American- developed just twothirds as many breast cancers as rats
given no CLA. In his paper published
recently in Cancer Research, Ip further
suggests that CLA may reduce the susceptibility of breast tissue to malignant
changes.
Of the large number of naturally occurring substances that have demonstrated
anticancer activity, all but a handful are
plant-derived. CLA is unique because it is
present in food derived from animals, and
its effectiveness is seen at dietary concentrations that are close to the levels consumed by humans.
"We just do not know the impact that
CLA alone has in the context of a high fat

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�·························· · ································ · ·············· · ·· · · · ·········· g]
. ·~"

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illegal cigarette sales net state,
federal governments big revenues
orty-six states garnered $71 million in taxes from the illegal sale of
cigarettes to minors in 1991, and
the federal government took in an
additional $51 million, according
to a study led by UB researchers.
California topped the states in illgotten tobacco revenues with an estimated $10.2 million, the data show,
followed by Texas at $8.2 million, ew
York at $7.2 million and Florida at $4.1
million.
Louisiana, Missouri, Montana and
ew Mexico were not included in the
illegal tax-revenue statistics because
these states had no law restricting the
sale of tobacco to minors as of 1991.
Since then, all 50 states and the District
of Columbia have passed laws banning
the sale of cigarettes to minors.
The report, recently published in

Are babies who are nursed protected later in life?

Women breast-fed as infants may
have lower risk of breast cancer
ew research from UB indicates that
women who were breast-fed as
infants may experience a measure
of protection against breast cancer later in life.
The UB study, involving 1,130
women from two counties in Western
ew York, indicated that women who
were breast-fed had a 25 percent lower
risk for developing breast cancer than
women who were bottle-fed as babies.
The study appeared in the May issue
of Epidemiology.
"There is growing interest in exposures in early life, including diet, and
their relationship to breast cancer risk,"
said jo Freudenheim, Ph.D., associate
professor of social and preventive medicine and the study's principal investigator.
"There has to be some sort of environmental component to explain the geographical variation in breast cancer rates.

American journal of Public Health,

tracked the illegal sale of cigarettes to
minors , by state, using a variety of national reports and studies.
It was authored by K. Michael
Cummings, Ph.D., associate research
professor and senior research scientist
at Roswell Park Cancer Institute; Terry
Pachacek, Ph.D., associate research professor of social and preventive medicine; and Donald Shopland of the ational Cancer Institute.
Other findings included:
~ Approximately 2. 7 million teenagu

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ers smoked an estimated 516 million
packs of cigarettes in 1991.
~ Federal and state governments
collected a total of more than $240
million on the sale of cigarettes to teens
12-18 years old.
~ Cigarette companies earned $190
million in profit from sales to teenagers
94.8 million of it from illegal sales
to minors.
Cummings said the report was intended to send a message to state governments.
"Despite laws prohibiting the sale of
tobacco products to minors, it's clear
teenage smokers can still buy cigarettes
easily. Studies show that when these
laws are enforced, illegal sales to minors can be reduced dramatically,"
Cummings said.
+

intake in humans," said Ip, who added
that the challenge of future research will
be to define the potential benefits of
CLA in the human diet, to characterize
its anticancer activities, to elucidate its
mechanism of action at the subcellular
level and to design new strategies for
enriching foods with CLA.
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Risk factors relating to exposures in
adulthood don't explain all the variation we see. This finding of a possible
protective effect from having been
breast-fed could be significant, and it is
certainly worth looking at further. "
Freudenheim and a team of researchers collected data on an array of potential risk factors from 528 women newly
diagnosed with breast cancer and 602
women with no cancer who were randomly selected from the same population and matched for age. The women
were between the ages of 40 and 85
during the time of the study, from 1986
to 1991.
After controlling for age, education, age
at menarche, age at first pregnancy, number of months they nursed their own
children, number of pregnancies, family
history of breast cancer, history of benign
breast disease and body-mass index and
height, the researchers found that one
aspect of early nutrition - whether a
woman had been breast-fed- was asso+
ciated with a decrease in risk.
BY

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�Buffalo General initiates third
state lung transplant program
he Buffalo General Hospital, in
cooperation with the School of
Medicine and Biomedical Sciences,
has become the third hospital in
ew York State to initiate a lung
transplantation program.
"This new service is an extension of
our heart transplant program and its
primary focus will be patients with endstage lung disease who reside in Upstate
New York (west and north of Albany),"
saidJoginder N. Bhayana, M.D., associate professor of surgery and director of
BGH's Heart/Lung Transplant Program.
In ew York State, only Columbia
Presbyterian Medical Center and The
Mount Sinai Medical Center in ew
York City offer lung transplantation in
addition to Buffalo General.
oting that more than 80 heart transplants have been performed by BGH
surgeons since 1984, Bhayana observed,
"Our team has extensive transplantation experience and is well-prepared to
perform lung transplants. "
According to Bhayana, by late April ,
28 people had already received preliminary evaluations for lung transplantation, and six were on the United etwork for Organ Sharing (U OS) list of
patients awaiting donor organs.
Bhayana said his transplant team
hopes to perform six to eight procedures annually.
"Obtaining lungs is more difficult than
hearts because many potential donors
are on respirators for several days prior
to dying," he noted, adding that the
chances of lung infection increase after
a patient has been on a respirator for 48
hours.
Unlike heart transplants, where organ rejection is the most critical postoperative factor, infection is the most

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serious concern after lung transplantation, he said.
Bhayana observed that a multi-disciplinary team was developed to manage
the evaluation, transplant surgery and
post-transplant care in cooperation with
the patient's primary care physician.
The team consists of representatives in
cardiothoracic surgery, pulmonary
medicine, cardiology, infectious disease,
psychiatry, nursing, pharmacy, pathology, rehabilitation medicine, nutritional
+
services and social work.

edge and technology of genome science.
"This very generous gift from the
Palisano family will allow Roswell Park
to endow its new program in cancer
genetics and to use the interest the funds
generate to support the research activities of its laboratory," said Thomas B.
Tomasi, M.D. , Ph.D. , president and CEO
ofRPCl.
Roswell now houses several hereditary cancer registries, including the Gilda
Radner Familial Ovarian Cancer Registry and the Familial Cancer Syndrome
Registry, and has plans to add three new
ones.
+

$1 million gift to Roswell will fund
new cancer genetics laboratory Medical/Dental staff officers
Buffalo family who lost six of its elected atteaching hospitals
members to cancer has pledged $1
million to Roswell Park Cancer
edical and dental staff officers
Institute to establish a cancer gewere elected recently at several
netics research laboratory.
DB-affiliated teaching hospitals.
The laboratory will be dedicated
At Sisters Hospital, Daniel A.
to the memory of John and Santa
Castellani, M.D., clinical instrucPalisano, whose first born, Vincent, at
tor in neurology, was elected
age l3 started a delivery business with a president. Also elected were Edward
horse and wagon that later spawned a Bartels, M.D., clinical instructor in gynumber of highly successful transporta- necology and obstetrics, president-elect;
tion companies, including Boss Linco Kenneth]. Eckhert, Jr., M.D. , clinical
Lines.
assistant professor of surgery, secretary;
Roswell received the gift from the and Nady Shehata, M.D. , treasurer.
Charles and Charlotte Palisano family
At The Buffalo General Hospital, Scott
and from the Vincent and Harriet A. Tulman, M.D. , clinical assistant proPalisano Foundation.
fessor of surgery, was elected president.
"lt is both a privilege and an honor to Also elected were Daniel A. Mariniello,
have a cancer research laboratory at M.D. , clinical associate professor of gyRoswell Park carry the name of my fam- necology and obstetrics, president-elect;
ily, said Charles ]. Palisano, whose Nancy Nielsen , M.D., SUNY trustee and
mother, Santa, three of his brothers, clinical assistant professor of microbiolVincent, Victor and Samuel, a sister, ogy and medicine, vice president; Daniel
Virginia, and niece, Diane, died of can- S. Camara, M.D., secretary; and john
cer.
DeBerry, M.D. , assistant professor of
The laboratory will be located within urology, treasurer.
Roswell's new Cancer Genetics and Gene
At The Children's Hospital of Buffalo,
Therapy Program, established to capi- Daniel Peroni, M.D. , professor of peditalize on the explosive growth in know!- atrics, was elected president; Russell S.
y

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Vaughan, M.D., clinical assistant professor of pediatrics, was elected vice
president; and Ehsan Afshani, M.D.,
professor of radiology and pediatrics,
was elected secretary-treasurer.
At Millard Fillmore Health System,
Thomas Cumbo, M.D., clinical associate professor of medicine, was elected
president. Also elected were Thomas
Lombardo, M.D., clinical instructor in
orthopaedics, president-elect; james
Burdick, M.D., clinical instructor in
anesthesiology, secretary; and Evan
Evans, M.D., clinical instructor and
Buswell fellow in surgery, treasurer. +

Children'srecruits nationally
renowned heart surgeon

Eliot Rosenkronz, M.D.

liot Rosenkranz, M.D., has joined
The Children's Hospital of Buffalo
to head its division of cardiovascular surgery.
Rosenkranz, who was recruited
from The Cleveland Clinic, holds
the position ofUB associate professor of
surgery. He will participate in clinical
and laboratory cardiovascular research
at both the medical school and
Children's.
"The successful recruitment of Eliot
Rosenkranz is a coup for Children's
Hospital," said joseph A. Ruffolo, the
hospital's president and chief executive
officer. "By leaving The Cleveland Clinic
and joining the staff at Children's Hospital, Dr. Rosenkranz is making a strong
statement as to his future investment
and commitment to the success of the
hospital."
A native of Glen Clove, ew York,
Rosenkranz is a graduate of the University of California at San Diego School of
Medicine. He completed his general residency at the University of California
and Los Angeles Medical Center.

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Rosenkranz was the head of the section of congenital heart surgery at The
Cleveland Clinic, responsible for pediatric and adult congenital heart surgery,
pediatric heart transplants and
arrhythmia surgery, as well as clinical
and laboratory research.
+

NFMMC wins Preferred Prtmary
Care Provider DOH designation
iagara Falls Memorial Medical
Center has recently been designated a Preferred Primary Care
Provider by the ew York State
Department of Health. lt is one
of only two hospitals in the eight
county Western ew York area Erie County Medical Center is the
other- to have won the designation.
Criteria to qualify for a Preferred Primary Care Provider include provisions
for preventive and interventive health
services, including immunizations and

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cervicaVbreast/colon cancer screening,
in addition to standard services such as
radiology, pharmacy and clinical laboratory.
The designation carries with it enhanced Medicaid reimbursement rates.
DOH also mandates that each Preferred Primary Care Provider hospital
establish a quality assurance program to
determine patient satisfaction and continuity of care. The program includes
development of an in-depth patient
tracking and referral system, a 24-houra-day telephone service for patient health
care inquiries and extended operational
hours.
The hospital 's primary care
resources include its Hamilton B. Mizer
Primary Care Center, which houses
18 programs, including Memorial
Pediatrics, its family practice residency
program, prenatal care assistance
program and numerous specialty care
clinics; the Summit Immediate
Treatment Center; and the Tuscarora
Health Center.
+

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PRACTICE MAKES
PERFECT
AFTER

10YEARS, US'S FACULTY

PRACTICE MANAGEMENT PLAN MAKES

SENSE FOR ITS FACULTY MEMBERS AND

THE PATIENTS AND STUDENTS THEY SERVE

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Buff

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Because so many different groups and individuals were
involved, and because negotiations were so complex, it
has taken a long time, much hard work and a great deal of
cooperation to make the University at Buffalo Faculty
Practice Management Plan into the efficient, cutting-edge
system its proponents believed it could be. But a decade
after its implementation, that's what the plan has become.
Mandated be ew York State legislature in the midl970s and implemented on january l , 1984, the practice

plan manages the income ofUB's widely varied and expert
medical and dental faculty in 20 different departments,
many of whom are widely dispersed at the school's
affiliated teaching hospitals.
"The plan has been extremely important to the development of the School ofMedicine and Biomedical Sciences,"
says] ohn aughton, M.D., vice president for clinical affairs,
dean of the School of Medicine and Biomedical Sciences
and chief administrative officer of the UB practice plan.

PAUL C. HOLMWOOD,

M.D.,

ASSISTANT

PROFESSOR OF
OPTHALMOLOGY , AT
LEFT, WITH MEDICAL
STUDENTS JOEL
SHAPIRO (SITTING)
AND ANDREW
FEINBERG , AT
MILLARD FILLMORE
HEALTH SYSTEM ' S
GATES CIRCLE EYE
CENTER. AT RIGHT,

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WITH RESIDENT
ESTHER SANTOS,

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M.D.,

DEMONSTRATING

A PROCEDURE.

L _______ __ _____________________ _ _________ _

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----,

the medical school together. Given where we are in
medicine right now, without the plan we would be
completely disorganized , not knowing how to respond
to many concerns," aughton says.
The practice plan better defines the role of departmental chairs, creates common ground rules for faculty and
provides funds both for the medical school and for
hospital overhead, aughton says. "The practice plan
brings about a more fairly shared enterprise," he says.
The practice plan organizes, limits and audits the
amount of money faculty physicians earn from clinical
practice. Earning limits are based on faculty rank. Under
the plan, physicians are allowed to earn no more than 250
percent, or in some cases 275 percent, of the maximum
base salary allowed to a professor of their rank. Physicians also contribute to the fund of the chief administrative officer of the plan. SUNY Central sets a new salary
cap every year.
"The cap presents different concerns for different
types of physicians," says ancy Glieco, assistant vice
president of clinical affairs and administrative staff person to the plan since its implementation. "For instance,
a family medicine
doctor is not going
to reach the salary
cap, whereas for an
orthopedic surgeon
the cap may be an
issue. " At the time of
its implementation,
the plan was highly
controversial because it controlled
physician incomes ,
Glieco says.
o one is more
aware of the complexity of the plan's
history than William
Dillon, M.D., an associate professor of
gynecology/a bs tetrics located at The
Children's Hospital
of Buffalo . President

UB's practice plan is its application of the State University of New York (SU Y) Faculty Practice Management
Plan. Covered by Article 16 of the policies of the board of
trustees of SU Y and negotiated by contract between the
Union of University Professors and the Office of Employee Relations , the SU Y-wide plan includes all of the
medical schools and dental schools in the SUNY system,
as well as the School of Optometry. The plan mandates
that all full-time and geographic full-time SU Y faculty
(those based at affiliated hospitals) must be members. The
plan is not required for volunteer or part-time faculty. At
each SUNY institution with a medical faculty, the plan is
administered by a governing board of that faculty .
The fact that UB faculty do not work at only one nearby
hospital, such as at SU Y-Stonybrook, but are dispersed
among eight area hospitals, makes the management of
UB's practice plan more complex than others in the SU Y
system.
"Without a centralized clinical faculty, and existing in
various places in the Western ew York community as we
do , the plan defined and brought together those who
make up the full-time faculty ofUB.lt's the glue that holds

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to have the honors and accolades associated with fulltime appointment to a medical school and the time to gain
professionally and in administrative ability."
According to Glieco, the plan has evolved significantly
over the 10 years it has been operating at UB. "When we
first started, we almost didn't know who all the people
involved were," she says. "The organization was very
loose - we collected money and patients however we
could.
"We've gone from being disorganized to being a department-centralized system with 20 departments and
very few compliance problems," Glieco says.
"The plan forces a member to have an organized
practice, so we know who's doing what and where they're
based," Glieco says. "Financing medical education has
become a much more important issue in the last 10 years,
and medical schools have changed from an unstructured
environment to becoming a real business. We negotiate
with teaching hospitals and each department, and this is
the fifth year of the department-by-department audit.
Here in the dean's office we think it's one of the best
things to happen in medicine in the last decade. "

of UB's Faculty Practice Management Plan governing
board since 1986, Dillon has been on the board from its
inception.
"In the beginning, it took a lot of work by the governing
board to educate faculty as to exactly what the practice
plan was, to answer their concerns and objections and to
work towards full compliance with the plan," Dillon says.
"It was a learning process for the board also," Dillon
says. "We needed to develop policies and procedures,
certain guidelines under which the departments would
function, and have the departments develop their own
plans for the management of clinical income while seeing
to it that those plans were consistent both with the overall
UB plan and with Article 16. It was not an easy feat, and
took a lot of talk and education over several years. "
For Dillon, all the work has been necessary and significant because of the plan's importance. "As state employees in a university system, there must be an accounting of
our income to the public," he says. "It's important that
some limits are placed on the amount of income generated
by one's private practice within the plan. Just as there are
benefits for being a faculty member of the SUNY system,
some of those benefits must be
referred back to the school, and
back to individual departments
also.
"The plan tries to allow SU Y
faculty members to make competitive earning with other peers
and yet do all the things a faculty
member does which are not income generating," Dillon says.
Although he admits that perceptions of the importance of being a UB faculty member may vary
among physicians, for Dillon that
importance seems clear. "I view
my employment as a teacher, researcher and administrator of a
medical school as a privilege," he
says. "It's a profound responsibility - the privilege of seeing to it
that a new generation of physicians are properly trained. With it
comes the chance to be at the
cutting edge of one's profession,

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manner," he says.
Currently, the plan gets good cooperation from the
departments, Dillon says. There's more centralization
within departments of their own finances , with reporting
on a monthly basis to the office of clinical affairs flowing
more freely and in a timely manner. The dean's tax
computation, which provides money for the chief administrative officer of the plan, is done on a uniform basis, as
is the computation for hospital overhead payment. Com-

Beginning with a 1990 audit of 1989 earnings, audits
have been done each year on a department-by-department basis by the accounting firm Levin and Associates.
As the plan geared up for that first audit in 1990, there
was a lot of concern about the cost of the audit procedure,
and more effort and education needed to be provided to
the departments, Dillon says. "Since that time , what
we've seen is that the yearly audit process has become
standardized, moves easily and is completed in a timely

LEONARD

FELD ,

ASSOCIATE

M.D. ,

PROFESSOR

OF PEDIATRICS , AT LEFT ,

WITH

RESIDENTS

ROB-

ERT WORONIECKI , M.D .,

( LEFT ) AND RANDY CAN-

TOS , M.D. , AT AN OUTPA-

TIENT

CLINICS

CHILDREN ' S

OF

AT

HOSPITAL

BUFFALO,

RIGHT,

WITH

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PATIENT

ANI BAL LARACUENTE AT

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THE CLINIC.

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pliance problems have decreased, and the vast majority of
faculty now fund their retirement plans directly through
the practice plan.
Dean aughton says that the practice plan has defined
much more clearly the role of department chairs from the
standpoint of operating the various clinical sites of the
medical school. "It gives department chairs the ability to
manage their faculty," aughton says. "Before the plan,
department chairs tended to have responsibility without
much authority. The practice plan has helped them
organize their faculty, and makes their position as department chair more secure."
The plan has led to the formation of a number of
facilitating organizations and legal entities to ensure its
proper functioning. One such organization is University
Medical Physicians Services (UMPS), which is the facilitator for the University Physician's Office, an ambulatory
multi-group practice site that operates at two campus
locations- the ground floor of the Cary-Farber-Sherman
Annex and a sports medicine site in Farber Hall- as well
as out of various offices in the teaching hospitals. Currently about 30 practice plan members see patients at the
University Physicians Office. The office also provides UB
medical students the opportunity to work directly with
patients. UMPS received not-for-profit status in 1993,
saving UB a great deal of money in state taxes.

Most UB departments have become more formalized in
their operations and have formed professional corporations, Dillon says. "Many of the more informal agreements between the hospitals and various departments or
individuals have been done away with," he says.
One department that has formed a professional corporation is the department of medicine, which currently has
faculty at five affiliated teaching hospitals. The University
Medicine Services Professional Corporation (UMSPC) is
a departmentally centralized plan, with the same rules
and goals for department faculty at all hospitals. Members
of all hospitals, as well as representatives of all specialties,
are represented on the department's practice plan governing board. The corporation is governed by the overall
umbrella of the UB-wide and SU Y Faculty Practice
Management Plan governing boards. The corporation has
a ceiling less than the 250 percent mandated by the overall
plan.
With the exception of a small group of on-campus
faculty, faculty in the department of medicine tend to be
hospital-based at one area hospital, according to james
olan, M.D. , president of the UMSPC, chair ofthe department of medicine and director of medicine at Erie County
Medical Center. "Since I took over as chair of the department in 1978, an increasingly large percentage of salary
dollars have needed to come from practice," olan says.

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want to say he had to be limited. If there's someone we can
recruit who is going to help patients in Buffalo, we should
work together to make sure the cap is not a stumbling
block. I think people are coming to understand that. "
Despite such issues, Feld agrees with Dillon that on the
whole the plan has been a great
success. "It's appropriate to have
a plan that covers all departments, and this plan is individually tailored to meet the needs of
various departments ," he says.
"For all practical purposes it's
worked pretty well. People will
always have complaints, and no
document is perfect for everyone. But if a majority like it,
then it's been successful.
"The practice plan provides a
system that allows faculty members to supplement their incomes in the academic environment so we can be competitive
and keep the people we want,"
Feld says. "In a university environment there have to be rules
so that people can better work
together. The practice plan gives
UB a team approach , and that's
what has made us so successful. "
aughton agrees with Nolan
that the issue of managed care
will be a key challenge for the
practice plan in the next decade.
"As we experience changes
in health care reform and financing, we will have to become more group-oriented,"
aughton says. "We will have to think as a group about
how we interface with the changing financial environment.
"We want to make sure the practice plan serves our
mission of education and research , and generates the
needed patient care activity," a ugh ton says. "The plan is
in place, has matured and is functioning well. There are
some real challenges out there , no doubt about it, but I
+
believe we can-face them. "

"This has made it necessary for faculty to do a lot more
practice, and has often put them in competition with the
larger community for patients.
"It's important to recognize that the practice plan only
organizes income, and is not a plan for organizing the
clinical practice of UB faculty, "
olan says. "We do not have a
university-wide group clinical
practice. But having such a practice will be very important as we
get into managed care, in which
people will want to work with
total care and not just particular
departments.
"Since UB faculty work at so
many area hospitals, we have to
be very attentive to the practice
of our various hospitals , each of
which has its own clinical
culture ," olan sa y s. " Our
department's faculty is spread
out between competing institutions , and our faculty have to
support the goals of their hospitals as well as [those] of UB."
Although Dillon admits that
a number of critically important
issues still need to be dealt with,
he believes the practice plan has
come a long way. "Continuing
issues will come up ," he says.
"But we have a very good track
record , and a responsive system
that can deal with those issues. "
Leonard Feld, M.D ., a member of the governing board from
1987 to 1990 and vice president of the board and chair of
finance and policy from 1989 to 1990, says one of those
key issues is how income limits will affect UB's ability to
be competitive in recruiting physicians in certain fields .
"There does need to be some flexibility on the limit," says
Feld, who is an associate professor of pediatrics and
physiology.
"If UB wants to recruit certain individuals, income
limits should not be a factor ," Feld says. "For instance, if
we wanted to recruit a top transplant surgeon, we wouldn't

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�II
THE NEW ACADEMIC MEDICAL COLLEGIUM GIVES ITS MEMBERS
AN EQlJAL SAY IN THE FUTURE OF HEALTH CARE IN BUFFALO

ANDREW

T'S MORE THAN JUST ANOTHER institutional name. To
people like Charles B. VanVorst, President of the Millard
Fillmore Health System, "Academic Medical Collegium"

*

says a lot.

"If you go back and look at Webster, the definition of

'collegium' is people sharing power on an equal basis."

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�W
LE IT'S STILL A WORK IN PROGRESS, the
proposed Academic Medical Collegium holds the promise of creating a strong but flexible alliance among the
University at Buffalo, its schools of Medicine and Biomedical Sciences and Dental Medicine and the eight
area hospitals already affiliated with the university for
graduate medical and dental education. There's also a
seat at the table for medical staff and faculty in the novel
organization, which proponents see as a vehicle for
taking the region's health care and medical education
systems into the next millennium.
"We're trying to get up a step and do more for the
community in a collaborative way," said Thomas R.
Beecher Jr. , former Buffalo General Hospital chairman
and a key player in the effort.
Medical school dean john Naughton, M.D. , a prime
mover behind the nascent organization, is optimistic.
"There's been a broad foundation of principles to
which most people have agreed," he said.
"The good news," aughton added , "is everybody
sees the appropriateness of moving toward cooperative
interfaces in an era of reform directed at health care and
health education that can be an overwhelming challenge to existing programs of quality."
By incorporating broad representation from the university, hospitals and physicians, the Academic Medical Collegium hopes to build on the success of the
existing Graduate Medical Dental Education Consortium, but to overcome the tensions that plagued a
previous cooperative project, the Western ew York
Health Sciences Consortium . If successful , the
Collegium would enhance the region's medical education and health care systems to a point where Buffalo
could become a national center of medical excellence.
At the moment, the Collegium is more concept than
concrete, but the concept is bold and its architects hope
to move from artist's rendering to actual blueprints this
autumn. The resulting structure would be something
of a meeting hall from which members could launch
collaborative efforts to enhance their academic and
health care missions. "The question ," said VanVorst,
"has got to be, how do you develop that forum with
institutions that are not merged or economically linked
to one another? I don't think it's a problem. I think it's
a challenge. "

Dean John Naughton, M.D., a prime mover behind the nascent organization, is optimistic it is •moving toward
cooperative interfaces in an era of reform directed at health care and health education."

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�Thomas R. Beecher, former Buffalo General Hospital chairman and a key player in the effort to build the Collegium, believes
the organization could harness "a powerful force in the community" to meet the challenges that health core reform will bring.

CCORDING TO THE
Collegium's statement of m1sswn and
principles, its focus would include everything from training and research to
quality, cost and access to care.
"There's a powerful force in the community if you
take these eight institutions and the university medical
complex to solve problems," Beecher said. It's too early
for the Collegium to be planning any specific projects,
but Beecher said there's no lack of possibilities. "If you
put the weight of the university and all these hospitals
into preventive medicine," he suggested, "a lot could be
accomplished. "
The Collegium would also serve as a communication
forum for member institutions and practitioners, whether
they be academic or community-based. And organizers
want to keep the doors open for non-member institutions and practitioners to collaborate, too.
"It's a very positive, almost ecumenical concept,"
said Gerald Sufrin, M.D., professor and chairman of
urology and chairman of the medical school's Council
of Clinical Department Chairpersons. "It's to improve
health care delivery in a broader sense. Packed into that
goes education and research, making young people the
best they can be. "
The organization would include the same institutions that make up UB's Graduate Medical Dental Education Consortium: the medical and dental schools, The
Buffalo General Hospital, The Children's Hospital of
Buffalo, Erie County Medical Center, Mercy Hospital,
Millard Fillmore Health System, Roswell Park Cancer
Institute, Sisters of Charity Hospital and the Buffalo VA
Medical Center. aughton said plans call for the
Collegium's board to include three people from each
institution, including the chief executive officer or
equivalent, the chief operating officer or designee and a
medical staff or faculty representative. UB will be represented by its president and vice president for clinical
affairs and chairman of the clinical council.
Some see the Collegium as a natural next step in the
development of cooperative efforts that began more than a

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�Charles B. Van Vorst, president of Millard Fillmore Health System, sees the Collegium as a forum from which member "institutions that are
not merged or economically linked to one another" can launch collaborative efforts to enhance their academic and health care missions.

decade ago with formation of the graduate medical education consortium, the organization that serves as the sponsoring institution for the numerous residency programs
spread among UB's affiliated hospitals. While many had
once viewed Buffalo's lack of a single university medical
center as a drawback, the consortium has come to be seen
as a model for other communities and a promising arrangement for implementing graduate medical education reforms , such as greater numbers of primary care slots. "It
has drawn national attention," said William D. Pike, president of the Western ew York Hospital Association.
The graduate consortium also got the university and
the region's traditionally competitive hospitals used to
working more closely together. In 1987, they formed a
second alliance, the Western ew York Health Sciences
Consortium. Its goal was to enhance the quality of
health care in the region, and it was soon credited with
several high-profile successes, including establishment
of the Bone Marrow Transplant Center at Roswell Park,
the Heart-Lung Transplant Center at Buffalo General
and the Positron Emission Tomography center shared
initially by UB and the Buffalo VA Medical Center, and
now the Millard Fillmore Health System. Unlike the
graduate consortium, the health sciences consortium
was incorporated, giving it a more formal structure. And
the Buffalo business community, interested in keeping
health costs under control, played an important role in
its formation and operation, so much so that the organization was headed by a bank executive.
Despite its successes, the consortium ran into trouble.
"There was always tension about how much involvement the business community should have in decisionmaking," recalled aughton. To make matters worse,
physicians felt excluded. And hospitals, ever mindful of
their own autonomy, were edgy about being absorbed
into a de facto university medical center. Former UB
President Steven B. Sample suggested that the consortium could solve some of its problems by putting the
university in a stronger leadership position. The idea
was seriously considered, but it didn't make nervous
consortium members any more comfortable.
"Eventually that organization went on the back
burner," aughton said. "It hasn't been formally dissolved. But by gentleman's agreement, we decided to
strike out in new directions to form a more mutually
compatible organization."

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�LKS TOWARD THAT END have been going on at various levels for four years.
UB's new president, William Greiner, also became involved, and by this summer the
Collegium reached the point where everyone was preparing to sign off on a statement
of mission and principles. It's an ambitious document that targets four areas: medical
education; health care delivery; biomedical research; and the region's national standing.
The document states that the Collegium would "Enhance the ability of its members to fulfill their respective
academic roles, including those related to education of
health care professionals .... " While it goes on to indicate
that the Collegium would absorb the graduate education
consortium, Beecher said that issue will remain uncertain until members get to work on specific operating
plans.
As for health care, the statement charges the Collegium
with developing "organized approaches to meeting community health needs that strike a balance between collaboration and competition in addressing major health
care issues, including quality, access and cost of care."
Among other things, it says the Collegiu m would: facilitate availability of the best preventive, diagnostic and
treatment modalities; foster efficient resource use and
avoid unnecessary duplications; promote primary care
access for underserved groups in the region; and encourage, where appropriate, resource sharing and joint support of activities.
"I think this complements wherever health care reform takes us," said Robert Stanek, chief executive of
Mercy Hospital. "But more importantly, it's good for the
community."
The mission and principles statement also says the
Collegium would bolster biomedical research, partly by
creating alliances of common interest that would "gain
from clinical and organizational diversity among programs, departments and institutions." Such efforts might
not only advance the body of health sciences knowledge,
but could also help the area compete more successfully
for research funds and establish it as a national biomedical research leader.
The document also says the Collegium would encourage health services research into issues of quality,

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access, cost and appropriateness. In addition, the organization would develop collaborative information systems, which could also serve educational and administrative needs.
"We can do very collaborative research among institutions," said Edwin Mirand, M.D., Roswell Park's vice
president for educational affairs and dean of its graduate
division of the UB medical school. "We can get greater
numbers into the treatment schedules. You're always
looking for patients to come into protocols, and one
institution may not have one type of patient, but a group
of institutions might. "
Finally, the Collegium would work to advance the
regional and national reputation of not only its members, but of the entire local health care community. In
particular, it would identify collaborative opportunities
to retain patients within the region and encourage "services of excellence."
To answer physician concerns, Collegium planners
added a section to the mission and principles statement
in May that provides for proportional representation
among institutions, medical and dental staff and UB
faculty.
"I think some of the nervousness between the volunteer faculty and the full-time faculty has been diminished because a representative voice has been assured,"
aughton said.
Sufrin said the medical school's clinical department
chairpersons were among the first to endorse the
Collegium document. "In a sense, the faculty at large
could be considered another institution," he said. "From
our standpoint, we look upon the Collegium as an
extraordinary opportunity to work with the other health
care institutions in the system."
The mission and principles statement also says, among

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�Gerold Sufrin, M.D., professor and chairman of urology and chairman of the Council of Clinical Deportment Chairpersons, describes the
Collegium as "a very positive, almost ecumenical concept" that will "improve health core delivery in a brooder sense."

other things, that faculty appointments will not be universally required for medical and dental staff appointments to all teaching hospitals, and that the Collegium
itself will not enter arrangements to provide patient care
or other services unless all members and their staffs
agree.
"Keeping the physicians involved helps to round out
the system," said Stanek.
With Collegium participants concerned about their
autonomy and everyone uncertain about the direction of
health care reform, it hasn't been easy getting to this
point. But many are optimistic. "I think it's good and it'll
help health care delivery, research, education," said
Mirand. "Yes, you'll lose some independence. But it'll
also give us more opportunities. "
"There's no question that people are looking out for
their turf," said VanVorst. "But I do sense a broader winwin, a broader sense of community. I see a broader vision
or need emerging. I think it's good, and I hope we find a
way to build on that."
If all goes according to expectations, Collegium organizers will work this fall on an organizational structure to
carry out the lofty generalities of the mission and principles statement. Will the Collegium be incorporated?
Will it absorb the graduate education consortium? What
exactly will it do , and who will do it? It will probably be
the most difficult part of the process, Beecher said.

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VanVorst said he thinks the Collegium can avoid the
tensions that troubled the Health Sciences Consortium.
"I think it's a lesson," he said. "Also, that was several
years ago .... The environment has changed, the leadership of most of the hospitals has changed. I see that as
an opportunity. " The trick, he added, will be to move as
quickly as possible "without fracturing the process or
creating mistrust."
Stanek said member institutions shouldn't feel threatened as long as the Collegium takes a "planned, rational
approach." The organization may eventually try to reduce service duplications and encourage specialization
among hospitals, but some of that is happening already,
he said, pointing to developments like ECMC's traumaburn unit. Collegium or not, he added, downsizing is
occurring, and the Collegium could help member institutions cope with it better.
a ugh ton said he doesn't expect the Collegium to be
finalized overnight. "We're in a preparatory phase," he
said. "The actual formal organization may take another
year or two. We're in a process of evolution."
Still, he said, he sees the organization as being on the
leading edge of a trend that will grow, especially if the
basis of the Clinton health care plan is adopted. "I don't
think there is any doubt that the managed competition
theme will push every community to do more to develop
+
cooperative strategies for survival," he said.

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Moncada gives Harrington Lecture
INTERNATIONALLY RENOWN RESEARCHER FOCUSES ON
CLINICAL APPLICATIONS OF NITRIC OXIDE RESEARCH

alvador Moncada, M.D., who is
internationally known for his pioneering studies of nitric oxide and
its clinical applications, delivered
the D.W. Harrington lecture, " itric Oxide: Physiology, Pathophysiology and Therapeutic Implications,"
discussing the history of nitric oxide
research and some recent research on
nitric oxide that suggests significant
clinical possibilities.
Paresh Dandona, M.D., UB professor of medicine, introduced Moncada,
research director for the Wellcome
Research laboratories in England since
1986. Dandona praised Moncada as
"one of the most unique and creative
minds of our time," saying his work
"has inspired generations." While nitric oxide research was initially focused only on prostacyclin and related issues, Moncada helped expand
nitric oxide research to all areas of the
body, Dandona said.
Moncada, a member of England's
prestigious Royal Society who has received their gold medal, is credited with
the discovery that nitric oxide is the
endothelium-derived relaxing factor.
The author of more than 550 publications on vascular physiology and pharmacology, including seminal work on
modulation of prostaglandin release and
action by blood vessels, platelets and
endothelium, he is also a member of this
country's ational Academy of the Sciences.
Moncada said the determination that
vascular endothelial cells generated nitric oxide was made in 1987. A year

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later, researchers determined brain synapses also generated nitric oxide, leading to the suggestion that the formation
of nitric oxide from l-arginine, the synthetic precursor to nitric oxide, was a
widespread pathway for the regulation
of cell function and communication. It
was determined that nitric oxide acts as

MONCADA , A MEMBER O F
ENGLAND'S PRESTIGIOUS
ROY AL S OC IETY , IS CRED ITED
W ITH THE DISC OVERY
T HAT N ITRI C O XI DE IS T H E
ENDOTHELIUM· DERIVED
R ELA X ING FACTOR .

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an intermediary in such functions.
The discovery that l-M A (methyl
nitroso arginine - a derivative of larginine) was a selective and competitive inhibitor of the generation of nitric
oxide proved the most important tool
for the investigation of nitric oxide,
Moncada said. l-MNA produces a longlasting hypertensive response and
causes such effects as significant loss of
blood flow. Such effects can be immediately reverted by the injection of larginine, Moncada said.
The most interesting part of such a
finding, Moncada said, is that l-M A
does not increase blood pressure by
inducing vascular construction, but by
blocking the production of nitric oxide. Thus, in its normal physiological
state, the cardiovascular system is in a
state of active vasodilation, and a balanced system tends toward normal vasodilation.
Such research shows nitric oxide is
the endogenous dilator in the system,
Moncada said. itro-vasodilators act
the way they do because they are transformed into nitric oxide.
itric oxide, he said, performs numerous functions within the body, interacting with prostacyclin and inhibiting platelet aggregation and white cell
activation to regulate platelet and white
cell activity within the vessel wall. Evidence is also growing to suggest that
nitric oxide modulates vascular smooth
muscle cell proliferation via a cyclic
GMP-related mechanism , Moncada
said.
" itric oxide is a general regulator
that plays many different roles, "
Moncada said. "An interesting question is whether we can make compounds
that might be different from normal
vasodilators, which can lead to our selectively targeting specific vasodilators."
itric oxide is widely distributed in

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··· · ·~-·
I

in biological fluids may serve as a general marker of disease , Moncada said.
"All these functions of nitric oxide
are being established," Moncada said.
"How could we have understood blood
pressure before knowing this? Itnc
oxide, which in the atmosphere is known
as a pollutant, is also the first known gas
to act as a biological mediator. Could it
be that other gases also play a role in

the nervous system, he said, where neurons are highly interconnected, and nitric oxide neurons are very resistant to
processes of neurodegeneration.
Moncada said this further suggests that
nitric oxide may play a role in longterm potentiation - a major factor in
memory.
itric oxide may play many other
roles in the central nervous system as
well , Moncada suggested, including the
regulation of cerebral spinal fluid.
Research has discovered that white
cells also release nitric oxide, Moncada
said. Thus, while nitric oxide acts as a
biological mediator for physiological
purposes, when released by white cells
it has defensive purposes.
Nitric oxide is cytostatic and cytotoxic for tumor cells, bacteria, fungal
cells and protozoan parasites, Moncada
said, adding that activated white cells
release nitric oxide for a very long time.
At the moment, clinical applications
of nitric oxide research are focused on
the vessel wall area , Moncada said,
where nitric oxide-mediated vascular
relaxation can help regulate blood pressure. Also, it is clear that excessive
nitric oxide production can produce
hypertension in cases of septic shock.
itric oxide synthase inhibitors can
potentially manage such shock ,
Moncada said. "Whoever has been in an
intensive care unit trying to reverse the
effects of septic shock will agree this is
very important," he said.
Recent research has found an increase in nitric oxide production in all
parts of the body during pregnancy,
Moncada said. Such increased production could cause the decrease in vascular tone in pregnancy and other effects,
as well as help prevent heart disease in
pre-menopausal women.
Other research has suggested that
the breakdown products of nitric oxide

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animal systems? "
The Harrington Lecture is sponsored
by the School of Medicine and Biomedical Sciences. The D. W. Harrington Lecture Fund was established in 1886 by
Devillo White Harrington, M.D. , an 1861
graduate of the UB medical school and a
professor genito-urinary and venereal
diseases from 1886 to 1905.
+
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MARK

WALLACE

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3:

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Shirley Sampson, deputy director of Health Systems Agency, and Herbert Hauptman, Ph.D.,
president and scientific director of The Medical Foundation of Buffalo, speak at a health care
reform forum sponsored by Rep. Jack Quinn, R-Hamburg, held at the medical school in May.

Ebsary appointed assistant dean
and director of development
tephen Ebsary, Jr. , has been appointed assistant dean and director
of development for the School of
Medicine and Biomedical Sciences.
He has served the university in
various capacities
since 1988, including as
director of planned giving for the University at
Buffalo Foundation, Inc.
"Steve will help us
continue to build on our

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strong base of philanthropic support,"
said john aughton, M.D. , vice president for clinical affairs and dean of the
medical school. "We want to increase
the school's endowments and unrestricted support so that we can continue
to provide the excellent education for
medical and graduate students that has
earned us national prominence."
Ebsary, a graduate ofMuskingum College in ew Concord, Ohio, is a native of
East Aurora, ew York. Active in numerous fund-raising organizations, he is president of the Western ew York Planned
Giving Consortium and chairman of the
SUNY Task Force on Planned Giving. +

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· · ··········· · ··· · ·· · ··· ·· ·········· · ·· · · · ····· · ········ ··· · · ············ ·· ··· ·· ·· · ·····

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32 medical students receive
awards at commencement

don S. Ehrlich Award, the Mark S.
Petrino Award and the American Academy of Family Physicians President's
Award
hirty-two UB medical students
• Thomas Burnette, of Briarcliff
were honored during the school's Manor: the Baccelli Award and the Bercommencement held on May 15. nard H. Smith Memorial Award in CliniAmong the recipients were cal eurology
eight multiple award winners:
• Karen Houck, of Snyder: the Dr.
• Sean Perini, of Buffalo: the Cyrenius Chapin Award and the Hans
Dr. George Alker Award, the Robin M. ]. Lowenstein Award in Obstetrics
Bannerman Memorial Research Award,
• Christopher Wood of Williamsthe Dr. Cyrenius Chapin Award and the ville: the Dr. Thomas]. Guttuso Award
Upjohn Award
and the E.]. Weisenheimer Award
• Martha Bennett, of Cleveland, Ohio:
Other graduates receiving awards
the Charles Bauda Award, the Dr. were:
Cyrenius Chapin Award and the Stephen
• Diana Sanderson, of Tonawanda:
]. Paolini Award
the Gilbert M. Beck Memorial Prize in
• Steven Hammel, of Tonawanda: Psychiatry
the Buffalo Pediatric Society Award, the
• Katherine O'Donnell, of Buffalo:
David K. Miller Prize in Medicine and the Buffalo Surgical Society Prize in
the Morris and Sadie Stein Neuurgery
roanatomy Award
• joel Brenner, of Williamsville: the
• Andrea Williams, of Buffalo: the Children's Hospital Prize
Dean's Award, the orman Haber Me• Richard Kozak, of Buffalo: the Somorial Award and the ational Medical ciety for Academic Emergency MediAssociation Award
cine Award
• Kim Griswold, of Buffalo: the Gor• Todd Schlesinger, of Cleveland,

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Ohio: the Dr. Austin Flint Award
• joseph Kay , of Amherst: the
Bernhardt and Sophie B. Gottlieb Award
• Michael Krabak, of Buffalo: the
Francis]. Klocke Award
• Debra Tarantino, ofBuffalo: the Dr.
Heinrich Leonhardt Prize in Surgery
• Elizabeth McClintick, of Buffalo:
the Lierberman Award
•j ennifer Tufariello, ofWilliamsville:
the Maimonides Medical Society Award
• joseph Valenti, ofBuffalo: the Medical Society of the State of New York
Award
• Michael Landi, ofBuffalo: the Medical Alumni Association Award
• William Cecere, of Kenmore: the S.
Robert arins Memorial Award
• Douglas Golding, of Kenmore: the
G. orris Miner Memorial Award
• Glen Feltham, of Amherst: the Benjamin E. Obletz, M.D., Award
• john Pryor, of Buffalo: thejohn R.
Paine Award in Surgery
• Madonna Tomani, of West Seneca:
the Clyde L. Randall Society Award in
Gynecology-Obstetrics
• Mark Sheldon, ofBuffalo: the Emilie

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Lambert retires as Red Cross
Blood Services principal officer

nize those who donate six or more times
per year.
Under Lambert's direction, the Red
Cross' Buffalo laboratory consistently
eginald Lambert, Ph.D., has re- extracted the highest number of prodtired his position as principal of- ucts per donated unit of blood in the
ficer of Blood Services, Buffalo Red Cross system. In 1993, the national
Region after 21 years of service to component production average was 2.6
products per donated unit. The Buffalo
the American Red Cross.
Lambert, professor emeritus of Region amassed 3.6 products per unit
microbiology, achieved many accom- average- enabling one unit of donated
plishments during his tenure- among blood to assist up to four patients and
them, the establishment of seven fixed fully maximizing each blood donor's
blood collection sites throughout West- time and efforts.
Also under Lambert's stewardship,
ern New York. As a result, the Buffalo
Region has consistently had the highest Buffalo was an early leader in the collecratio of donor per 100,000 population tion of platelets, pheresis in the early
of any large region in the Red Cross 1970s and was the first Red Cross blood
region to utilize a blood product irradiasystem.
One of Lambert's proudest moments tor.
Donald Dudley, an 18-year veteran
came in the early 1970s when he led the
Red Cross to adopt a "community re- of the American Red Cross, has been
sponsibility" philosophy rather than the named Interim Principal Officer for the
former "credit" system of blood dona- Buffalo Region. Dudley, who has served
tion. Lambert also fully understood the in a variety of positions at both the
strong personal commitment blood do- regional and national level, is currently
nors feel to the program, and in 1986 he serving as Interim Principal Officer for
established the "Sixer Club," to recog- the Rochester Blood Region as well. +

Davis Rodenberg Memorial Award
• Donna Stawasz, of Cheektowaga:
the PhilipP. Sang Memorial Award
• john Sherwood, of Buffalo: the john
Watson Award in Medicine
• john McArdle, ofYonkers: the john
Watson Award in Medicine
• Geoffrey Hobika, of Grand Island:
the james Platt White Society Award
• Michelle Penque, of Grand Island:
the Frederick B. Wilkes Pediatric Award
• Antonio Bird, ofBuffalo: the Farney
R. Wurlitzer Award
+

SMILES ABOUND AS THE MEDICAL
S C HOOL HELD ITS 148T H C OM·
MENCEMENT I N MAY. FROM LEFT TO
RIGHT , JEFFREY SEYMOUR , M . D .,
' 93 , CONGRATULATES NEW GRAD
P I NA C . SANELLI , M . D .; J O S E PH J .
FA LSON E. M . D ., MAKES HI S MOT HER
MARYANNE PROUD ; AND BEHZAD
TABIBIAN ( STANDING) AND MICHAEL
LANDI ENJOY THE CEREMONIES .

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Kristen Schenck-Robillard

Med student takes first place
honors in AAFP research forum
B medical student Kristen SchenckRobillard was the recipient of the
First Place Research Forum Award
at the ew York State Academy of
Family Practice's annual meeting
May 8, 1994, in Saratoga Springs,
ew York.
The title of Schenck-Robillard's research paper was "Predictors of First
Contact Care in a Poor Urban Census
Tract. " She competed against other
medical and biomedical sciences students, as well as residents and attending
physicians for the award.
Carlosjaen, M.D., senior clinical investigator and clinical assistant professor of family medicine, is SchenckRobillard's research faculty leader, supervising her research endeavors.
"If Kristen has expressed interest in
becoming a family doctor, the specialty
would be lucky to have her," jaen said.
Schenck-Robillard, a native Buffalonian who attended Canisius College for
her undergraduate education, is a member of the Class of 1996. She is expecting
her first child in October.
Schenck-Robillard will also present
her paper to a national audience at the

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American Academy of Famil y
Practice's scientific assembly held
in September in
Boston , Massachusetts.
Two other UB
medical students
presented papers
at the Saratoga
Springs conference. jennifer
Zubler, Class of
1995 , presented "Use of Ultrasonography."
Patricia Krebs , also a member of the
Class of 1995, presented "Violent Acts
in Rural Settings. " Krebs will also present
at the AAFP's scientific assembly in Boston.
+
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EBECCA

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RIERLEY

Rosenthal named chairman of
family medicine department
homas C. Rosenthal , M.D., associate professor of family medicine
and a 1975 UB medical school
graduate, has been named chair of
the department of family medicine.
Rosenthal has served as interim chair
for the past year. A member of the department since 1978, he was instrumental in establishing the division of rural
health, the medical school's rural health
campus in Cuba , ew York, and its
residency program in rural health, one
of four in the country.
Through his initiative, UB was named
a ew York Rural Health Research Center in 1992, and one of five universities
in the U.S. designated as national rural
health research centers. He received the
1992 Distinguished Educator Award
from the ational Rural Health Associah

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tion for his work in expanding and improving rural health care.
Rosenthal also
is founding director ofUB's Primary
Care Resource
Center, headquarters for projects
implemented
through the school's
primary-care initiative, a cooperative
effort begun in 1992 to increase the number of medical school graduates entering
primary-care practice.
Rosenthal is project director of the
Generalist Physician Initiative grant
from the Robert Wood johnson Foundation.
+

Sarkin elected chair of pediatric
association education group
ichard Sarkin, M.D., clinical assistant professor of pediatrics, has
been elected chair of the Ambulatory Pediatric Association's Special Interest Group for Medical
Student Education.
Sarkin also is a member of the executive committee of the council on medical student education in pediatrics. +

Departmental name changes
better reflect academic disciplines
o better reflect the scope of their
disciplines and missions , two
medical school departments have
recently undergone name changes.
The department of pharmacology and therapeutics is now officially the department of pharmacology
and toxicology, and the department of
anatomical sciences is now officially the
department of anatomy and cell biology.
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�ity, cost-effective, efficient care to all of
the country's citizens in a larger variety
of community-sited environments. This
can be done only if more physicians are
prepared to work in new settings and to
focus on our many unmet needs.
"UB is proud to be included among
the schools that will provide the needed
leadership for change in the years ahead,"
he added.
The grant will support the following
activities:
• Recruiting underserved and rural
students
• Pairing promising high school students with primary care faculty during
the summer
• Restructuring some courses to include more emphasis on primary care
clinical approaches, as well as developing new courses
• Teaching information management
skills to medical students
• Training medical student in
multidisciplinary teams with nurse practitioners, physician's assistants, therapists and social workers
• Moving primary care medical
clerkships out of hospitals and into clinics
and doctors' offices in the community
• Hiring a director of education development to help design new courses
and programs, and a medical education
specialist to train faculty to implement
the initiatives
"The Robert Wood johnson granl
offers us a tremendous opportunity to
unite the goals of the primary care departments and to produce high-quality
clinical graduates who will be more likely
to enter primary care," said Thomas
Rosenthal, M.D., chair of the department of family medicine and the grant's
project director. "Those who don't enter primary care will have a better understanding of the challenges patients
face in our health care system."
The medical school has set a goal of

UB wins $60,000 Robert Wood
Johnson Foundation grant
he School of Medicine and Biomedical Sciences will receive approximately $600,000 over three
years from the Robert Wood
johnson Foundation to support
the medical school's efforts to redesign its medical education curriculum and to increase the number of primary care physicians it graduates.
In three years, after a successful evaluation, the foundation will continue to
support UB's primary care education
efforts through a non-competitive threeyear grant.
UB is one of 14 U.S. schools to receive a Generalist Physician Initiative
implementation grant. The money will
allow the university to carry out recommendations developed during an 18month planning period, funded in 1992
through a $150,000 award from the foundation.
The Generalist Physician Initiative
grant will enable the medical school to
begin its primary care recruitment efforts in high school, and to develop
projects and programs that will give
medical school students early hands-on
experience in primary care. Studies have
shown that early positive exposure can
influence students to choose careers in
primary care medicine .
"The faculty and I are elated by the
designation from the Robert Wood
johnson Foundation to participate further in the Generalist Physician Initiative," saidjohn P. aughton, M.D., dean
of the medical school and vice president
for clinical affairs.
"Medical schools and their teaching
hospitals have done much since World
War II to improve the quality of patient
care and to eradicate curable diseases.
Today, the challenge is to provide qual-

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having 50 percent of its graduates eventually practicing in primary care fields.
In September 1992, the school
launched its own primary care initiative
devoted to graduate medical education
when it unveiled a $5 million demonstration project involving six Buffalo
teaching hospitals, Medicaid, four private health care insurers and the ew
York State Department of Health.
That effort concentrates on recruiting medical school graduates into primary care residencies, improving faculty and resident teaching, setting up
community academic practice sites and
developing primary care research opportunities.
The Robert Wood johnson Foundation, headquartered in Princeton, New
jersey, is the nation's largest philanthropic organization devoted to improv+
ing health care.
BY

LOIS

BAKER

Ginsberg receives Triological
Society Presidential Citation
rwinA. Ginsberg, M.D. ,adjunctclinical professor, has been awarded the
Presidential Citation of the American Laryngological, Rhinological and
Otological Society. The founder and
president of the Buffalo Oto laryngology Group received the award
for his internationally recognized contributions to the research, diagnosis and
treatment of hearing disorders. The Society, also known as the Triological Society, presented the citation at its annual conference in West Palm Beach,
Florida.
Ginsberg received the award for his
pioneering research and practice in
middle ear microsurgery and cochlear
implants, as well as his work in the
education of the deaf.
+

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�Roswell Park Cancer Institute founded as part of UB

NATIONAL CANCER INSTITUTE-DESIGNATED COMPREHENSIVE CANCER CENTER
HAD ITS ROOTS AS A THREE-ROOM LABORATORY AT 24 HIGH STREET

he first government-supported get into the business of disease research.
cancer research laboratory in the
But a year later when the bill was
world had its beginnings in three passed a second time, he changed his
rooms of the old University of mind and signed it. The state continued
Buffalo building at 24 High Street. to support the laboratory until 1903
The laboratory, then known as when another governor, Benjamin B.
the ew York State Pathological LaboOdell, faced with a shortage of funds,
ratory of the University of Buffalo, had
threatened to veto the appropriation.
been set up under a grant of
$7,500 from the state legislature in 1898.
The enabling legislation
specified that the money was
to provide for "the equipment and maintenance of a
laboratory devoted to an investigation into the causes,
nature, mortality rate and
treatment of cancer."
Today, it is Roswell Park
Cancer Institute, named for
the UB professor who fought
for its creation and served as Roswell Park Cancer Institute, circa 1935
its director for its first six years.
Again, Butler exerted his considerable
Park had come to Buffalo as profesinfluence until the bill was signed. State
sor of surgery at the 4 7-year-old unisupport was never in doubt again, though
the amount was sometimes in question.
versity. One of the first things he noted
In two years the laboratory outgrew
was the greater incidence of cancer here
than in Illinois, where he previously
the medical school space. With money
publicly raised, land was purchased on
practiced and taught. He called the disease "the pathological mystery of the
High Street across from The Buffalo
ages. " Despite that, the University of General Hospital, and the first building
in the world constructed solely for canBuffalo had no funds for cancer research, so Park turned to the state.
cerresearch was opened in mid-1901.It
He enlisted the support of Edward
was named the Gratwick Research Laboratory of the University of Buffalo in
H. Butler, editor and publisher of The
Buffalo ews, who wielded consider- recognition of Mrs. William Gratwick,
who underwrote it with a $25,000 grant.
able influence with the legislature.
In 1911, Roswell Park, no longer
The legislature approved a grant,
but Governor FrankS. Black vetoed the
director but still actively interested in
bill,questioningwhetherthestateshould
the laboratory, led a move to have it

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taken over by the state and it became the
ew York State Institute for the Study of
Malignant Diseases. In 1946, its name
was changed to the Roswell Park Memorial Institute, in honor of its founder.
During its early UB years, the laboratory had a staff of l 2 - five of them
professionals. In 1903, they published
five scientific papers.
The laboratory maintaineda colonyof3,000 mice
and 300 rats for research in
spontaneous and transplantable tumors, and studied antibodies in mice recovering
from experimental tumors.
George ] . A. Clowes,
M.D. , a member of the early
staff, introduced experimental drugs in the treatment of
cancer for the first time in
the U.S. Later, working for
Eli Lilly &amp; Co., he helped
develop methods for the commercial
manufacture and use of insulin, for
which he received the Banting Medal of
the American Diabetes Association. Because of his work, four of his former
faculty associates at UB were among the
first to get insulin for their patients.
Today, Roswell Park Cancer Institute is no longer officially a part of UB,
although they are both ew York State
public institutions. The institute serves
as a teaching arm of the university the RPCI Graduate Division; students
rotate through it for experience in treating patients with cancer. It was recently
designated a Comprehensive Cancer Center by the ational Cancer Institute. +
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�Spring Clinical Day and Reunion
Weekend held April29 and 30

At left, University at
Buffalo president
William R. Greiner, and
below, John M. Canty,
M.D., ' 79, associate
professor of medicine,
address the gathering.

his year's Spring Clinical Day
and Reunion Weekend, held
April29 and 30, was a resounding success that saw friends and
colleagues come together to
reminisce and renew friendships.
As these photographs of the events
attest, a good time was had by all! +

At left, this year's Reunion Classes
enjoying the festivities. Above,
outgoing Medical Alumni Association
president Robert Reisman, M.D.,' 56,
presents an Alumni Achievement
Award to James F. Mohn, M.D., '44,
as Jerome P. Kassirer, M.D.' 57,
editor of the New England Journal of
Medicine, looks on. Other Alumni
Achievement Award winners were
Andrew A. Gage, M.D., '44; William
R. Kinkel, M.D., '54; and Max
Schneider, M.D., '49. At right, Paula
L. Stillman, M.D., former provost
and dean of Eastern Virginia Medical
School, speaks to participants at the
program.

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�Reunion Portraits: Pictures of 55 Years of Success
ere, Buffalo Physician presents the 10 classes that were
honored at this year's Reunion Weekend, including
the Class of 1939, which met informally to celebrate

+

55 years of medicine.

LEFT TORIGHT- FIRST ROW: Frank T. Riforgiato, Elizabeth Olmsted Ross
SECONDROW: Anthony V. Postoloff, Roy E. eibel, George C. Brady, john H.
Geckler

LEFTTO RIGHT- FIRST ROW: Richard Egan, Paul Weygandt, Sidney chaer,james
F. Mohn , Irwin Ginsberg

SECOND ROW: Anthony Aquilina, Willard Boardman, Raymond Hudson,
Frank H. Long, Jr. , Herman Edelberg, Howard Barnett, Helmut Mueller,
Sam Cassara, Newland Fountain, Francis Marchetta, Casimir Pietraczek

THIRD ROW: Clinton Strong, Raymond Bondi, Frank T. Frost, james Sullivan,
Robert G. Wilkinson,

Jr. , Theodore Prentice, William Potts, Thomas

Frawley, Andrew A. Gage, Edmund Collins, William Nowill

LEFT TO RIGHT- FIRST ROW: Carmelo Armenia, jacqueline Paroski, julia M.
Cullen, joseph Bradley Aust, Jr.

SECONDROW: Ralph S. Canter, Richard Schwanz, james Werick, George
Erickson, Paul T. Buerger,john T. Sharp, Pierce Weinstein, Max Schneider,
Harold Bernhard

THIRD ROW: Charles Bathrick, Philip C. Dennen

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•
lEFT TO RIGHT- FIRST ROW: Edward Wenzlaff, Charles Marino, Allen Lesswing,
Paul Weinmann, Robert M. Oshrin,

icholas Carosella, Donald Murray

SECOND ROW: jacob Lemann, Jr., Donald Wilson, Byron Genner, William
Howard,

orbert Kuberka, john L. Conboy, Robert Miller

THIRD ROW: Richard Mayer, William Kinkel, Edward Rayhill , Alfred Wolfsohn

lEFT TO RIGHT -

FIRST ROW: Daniel Kozera, Elton M. Rock, andra Wilt e

Leininger, Eli M. Isaacs

SECOND ROW: Constantine]. G. Cretekos,johnj. McMahon, William Blaisdell,
joseph F. Monte, George Baeumler, Thomas Doeblin, james M. Cole,
Richard A. Falls, Daniel Ninburg

lEFT TO RIGHT- FIRSTROW: joseph DiPoala, Anthony Ferrari
SECOND ROW: james Tibbetts, Jr., David Weinstein, john A. Manzari,
Elizabeth Serrage, Michael Goldhamer, Charles LaDoulis, Gerald Goldstein

THIRD ROW: George Glowacki, Stephen P. Katz, Irving Sterman,]. Frederick
Painton, Jr. , Marvin Z. Kurian , Richard Wolin , Bela F. Ballo, David A.
Leff, Michael Feinstein, Lawrence Casazza

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LEFT TO RIGHT- FIRST ROW: Dorothea Downey, Penny A. Gardner, Moira J.
Burke, Marion Wind-Pisick, David M. Sherer, Evelyn Hirschorn Roisman,
Madeline White, Barry Weinstein
SECOND ROW: Joel B. Bowers, Robert]. Gibson, Michael Pugliese, Michael
Pisick, Hachiro

akamura, Robert Hartog, louis Hevizy, Gerald Stinziano,

James Cavalieri, Samuel Weissman, Bernard Muscato
THIRD ROW: David F. Hayes, Timothy Harrington, Daniel Mandelbaum,
Hanley Horwitz, James Patterson, Douglas Roberts, Thomas Scanlon,James
White

LEFT TO RIGHT- FIRST ROW: Lawrence Oufiero, Diane Matuszak
SECOND ROW:James A. Smith, Paul Wierzbieniec, Stephen Yerkovich,John H.
Clark, Richard]. Buckley, Jr., James l. Budny, Joseph P. Lemmer, Bruce
Middendorf, Bradley T. Truax, Roy E. Seibel,Jr. , Thomas l. Walsh, Edward
Valentine

LEFTTO RIGHT- FIRST ROW: Peter E. Shields, Sonia L. Wornum, Ivonne Cellino,
Robin H. Adair
SECOND ROW;John Canry, Donald Armenia, Joh n Corbelli , Arth ur Rosiello,
joseph Buran, Jr., Michael Cellino, Charles Francemone, Walter A. Balon,
Ramon]. Pabalan, Andrew ]. Majka, John W . Crofts

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�··· ·· · ·· ·· ·· ·· · ···· ·· ······· ·· ·· · · ··· ·· ·· ·· · ·· · · ··· · ··· · · ···· ·· · · · · ····· · ··· ·· ······ · ··· •

ij

LEFT TO RIGHT- FIRST ROW:

Benson Zoghlin. Michael McMullen, Andrew

LEnTO RIGHT -FIRSTROW: Amy R. Jeffery, KaraM. Kelly, Diane M. Cicatello,

Knoll, David Pfalzer, Laurajo Booth, Raymond Chan SECOND ROW: Susan

Rodney j. Voisine, Mary Schamann, LoriAnn Fraas-Burns, Richard E.

Abbott, Evelyn Hurvitz, MoritzaAlvarado, Amy Schueckler, Mark Billinson

Ferguson, Debra M. Omiatek, Carolyn]. Piver, Lee R. Guterman SECOND

THIRD ROW: Fitzroy Dawkins,john McLaughlin,julie Dressloch, Mina Ohm,

ROW: David R. Bloom , Kristina E. Han, Andrea L. Messina, Douglas Sillart,

ora Meaney-Elman, Madeline Lalia, Kevin Rosteing, Paul Greenberg,

Pamela D. Reed, Dawn A. Gais, Mark Pundt, Thomas Grimald i THIRD

Seth Matarasso, William Healy FOURTH ROW: Thomas Mahl, Douglas Bates,

ROW:Kevin M. Senn, Raul Vazquez, Michael Licata, Wayne A. Forde, Leonid

Kenton Forte, Marc ]. Kublick,John A. Brach , Herbert

Shkolnik, Paul]. Lecat, Eric R. Southard, Henry M. Stachura

ewton,John G.

Dyster,john Lupiano, Paul Misthos, And rew Tanner, Randall A. Solomon

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Pl iO phone from Cellular One. Simple as that.
ow, owning a cellular phone from Cellular
One never felt so good. To contribute to the
Ronald McDonald House* and get your free
cellular phone, visit any Cellular One store or
participating dealer or call 861-9680. But hurry,

Buffalo's Ronald McDonald

though. This offer expires September 30, 1994.

'-l.~ff.~;;;;~~o..1J House*, one of 160 facilitie

CELLUlAR ONE.

around the world, each providing a
seriously ill children being treated at local hospitals. At
the same time, your donation also gets you a free NEC

861--9680
contact Paula Omicioli

Make your check payable to: Ronald McDonald House•
• Offer conun,amt upon new acovauon, equtpmmt contract and cm:ltt approval w1th Cellular~ m the aevm-county Westttn Nc.- Yorit area. Cellular c::&gt;nt
reserves the rteht to substitute equ1pmem. A one-t~ acovaoon fee apphes. EqUipment conmcu and rate plans vary. Certam temu and c.ondiUON apply.

�~ -· · · ······· · · · ··· · ········ ·· ····· · ······· · ··· · ···· · ······ · · ·· ·· ·· · · ······ · ··············

1181

Eugene Farber '43, focused his career on integrating
clinical specialty of dermatology with basic science

B UFFALO NATIVE SPENT 37 YEARS AT STANFORD AS A C LI NICIAN , EDUCATOR
AND ADMINISTRATOR , AND FOUNDED T HE PSORIASIS R ESEARCH INSTIT UTE

uring a guest lecture at the Central
Research Institute of Dermatology in Soviet Georgia in 1977,
Eugene Farber, M.D., attempted
to inject some humor into his presentation by projecting pictures of
California, his adopted home. One by
one, Farber held up pictures of famous
West Coast attractions: Fishermen's
Wharf, Chinatown, the giant redwood
trees.
"My interpreter repeated that the
redwood trees are so tall that when
Sputnik flew over it almost hit the top of
the trees," Farber recalled. " obody
laughed."
It was probably the only "bomb"
dropped in Cold War history.
Although Eugene Farber may not
ever be recognized for his stage presence, the accomplished physician-researcher can be credited with helping to
transform dermatology from a clinical
specialty to a discipline with a close
integration with basic science.
A native of Buffalo, ew York, Farber
received a B.A. degree from Oberlin
College in 1939, his M.D. degree from
the University ofBuffalo in March, 1943,
his M.S. degree from the University of
Minnesota in 1946 and served his residency at the Mayo Clinic from 1944 to
1948.
From 1949 to 1986, Farber served at
the Stanford University School of Medicine as a clinician, educator, research
investigator and administrator. He completed his career at Stanford as a profesB

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sor of dermatology and chairman of the
department of dermatology, a position
he held from 1959 to 1986.
It was at Stanford where Farber began to pioneer independent departmental status for dermatology. "In order for
dermatology to grow as a specialty, with
its own individuality and greater room
for development, I believed it was necessary to have equal status with other
clinical disciplines," Farber said.
This desire for independence can be
considered the landmark in the evolution of dermatologic research on both
the basic science and applied levels,
specifically in the study of psoriasis.
Until well into the 20th century, published knowledge of this disease was
almost entirely descriptive. From the
genesis of his career, Farber linked clinical observations with laboratory studies.
"I enjoyed teaching the longer I was
in it. My professorship at Stanford included teaching combined with patient
care and research. When I visited my
patients, I would always have three or
four students with me. It was important
for them to actually see patients and to
get first-hand experience with different
maladies," Farber said. "The research
part occupied my nights and weekends.
I worked at least 60 hours per week
during my career, but I enjoyed it."
It was his desire for expanded knowledge and increased research that led to
the First International Symposium on
Psoriasis, held in 1971. Three more were

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to follow at five-year intervals. Throughout his career, Farber has lectured in 44
different countries and has received
honorary memberships and awards from
more than 26 foreign dermatology societies. He is the author of several hundred scientific publications and four
books.
He recalls that one of his most memorable collaborations was in ewfoundland, British Columbia, where Farber
teamed up with Dr. Wayne Gulliver, a
professor of dermatology at St. John's
University. Farber and Gulliver were
investigating a five percent prevalence
of psoriasis in a population that was
considered to be a closed community.
"There was a very low rate of divorce
and most of the people living there are
married within the community," Farber
said. "We had an excellent opportunity
to undertake genetic analysis of entire
families," Farber said. "Evidence pointed
to the sixth and seventeenth chromosomes, which demonstrated linkages in
the family studies."
Upon his "retirement" from Stanford,
Farber co-founded the Psoriasis Research Institute, a non-profit foundation in Palo Alto. Originally established
with a skin biology unit specializing in
psoriasis, the institute expanded in 1989,
adding a clinical-pharmacology division
and a psoriasis medical treatment center. Although the main emphasis of the
institute's work is research, Farber said
that patients receive treatment daily at
the facility.

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"We have a large program in
Farber also recalled Abraham Aaron,
psychoneuroimmunology, a field of M.D. , a professor of gastro-neurological
great pertinence to people who have medicine, whose strict style of teaching
diseases of the skin," Farber said. "We was respected and admired by the stuare investigating biochemical and im- dents.
munological mechanisms which account
"We were afraid of him, but his discifor the so-called mind-body relation- pline as a physician was exemplary,"
ships.
Farber added.
"Seventy-five percent of psoriasis is
In 1993, Farber returned to Buffalo
stress-related. We are, therefore, look- to attend his 50th class reunion. "I could
ing at the sensory nervous system of the hardly believe how old we had become,"
skin with particular attention to neu- he quipped.
ropeptides," Farber said. Theresearch, he said, is aimed at identifying antagonists to the neuropeptides, the suspected trigger of psoriasis and other skin
diseases, in an effort to block
their release and prevent the occurrence of the skin condition.
The Institute also provides a
total care program to individuals
suffering from skin disorders.
Farber believes it is important
for patients and family members
to learn about their disease. The
total care concept includes access to educational materials and
conventional and non-traditional Eugene Farber, M.D.
treatment, such as auto-hypnosis, re"I was pleased to know what fine
careers my classmates had. When I
laxation techniques and diet.
"After a period of total care, the need graduated from Buffalo and went to the
for aggressive skin treatment is less- Mayo Clinic, I found that what Buffalo
ened," Farber said.
taught allowed me to compete successThroughout his career Farber has fully with students from the top medical
assumedleadershippositionsinnumer- schools in the country," Farber said.
ous dermatologic societies and organiLooking back to his early days as a
zations. He is past president of the Soci- medical student, Farber observed draety for Investigative Dermatology, the matic changes in the way medicine is
Pacific Dermatology Association and the taught today. "Medical school faculties
Association of University Professors. He have advanced beyond having their stuis an honorary member of the Buffalo dentssimply memorizeGray'sAnatomy,
for example."
Chapter of AOA.
Farber credits his initial interest in
"There is much more practical applidermatology to Earl Osborne, M.D., a cation in the teaching of medicine toUniversity ofBuffaloprofessor, who was day," he said. Yet for all the progress in
"dynamic and exciting in his teaching of medicine and medical schools, Farber
dermatology."
laments the "tough choices" facing the

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medical students of today.
"Medical students are faced with paying off huge debt. This shortens their
career expectations because they can't
hang on to specializing. It's just too
expensive," Farber said. "The coming
government requirements on how many
specialists can be permitted to enter any
particular field will also affect career
choices and the possibly the quality of
medical care.
"The government wants medical
schools to produce more family
doctors, but medicine is too
complicated today, and we need
specialists. You can't be a jackof-all-trades," Farber said.
Many UB stude nts and
alumni will recognize Farber
Hall on the University's South
Campus. The building, however, is named after the late Dr.
Sydney Farber, the noted
dermatologist's brother, who,
after graduating from the University of Buffalo, taught at the
Harvard University School of
Medicine for 4 1 years and
founded the Dana Farber Cancer Center.
There is a long association between
the Farber family and UB.Jason Farber,
M.D., was clinical researcher of chest
medicine at University of Buffalo, while
Marvin Farber, Ph.D., headed the
university's philosophy department.
Another brother, Seymour Farber,
served as vice president for graduate
education at the University of California in San Francisco.
These days, Eugene Farber has reduced his work schedule to five days a
week, devoting more time to leisurely
reading and other pursuits. "I will take
early retirement when I am 100," Farber
said. However, there's no sign of the
+
good doctor slowing down.
-

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SIGURDSON

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ml
48 UB alumni listed in
"Best Doctors in Amertca"
orty-eight alumni from the School
of Medicine and Biomedical Sciences have been named in the second edition of The Best Doctors in
America, a directory of the best in
the profession as chosen by their
peers.
Best Doctors lists 7,200 physicians in
more than 50 specialties - approximately 2 percent of the nation's 350,000
practicing physicians. UB has 28 faculty
members in the listing, compiled from
interviews with thousands o f specialis ts
throughout the country who were asked to
rate the clinical ability
of their peers.
UB alumni included
in Best Doctors are: Bernard S. Alpert, M.D. ,
' 74 , Reco n structive
and Microsurgery, San
Francisco, Ca.; Kenneth Z. Altshuler,
M.D., '52, General Psychiatry/Psychoanalysis, Dallas, Tx.; Joel M. Andres,
M.D., '68 , Pediatric Gastroenterology,
Gainesville, Fl.; William Balistreri, M.D.,
'70, Pediatric Gastroenterology, Cincinnati, Oh.; Karl R. Beutner, M.D. , '79,
Dermatology/Herpes Virus Infections,
Vallejo, Ca.; DavidA. Bloom, M.D., '71 ,
Pediatric Urology, Ann Arbor , Mi. ;
Marlene Bluestein, M.D., '76, Geriatric
Medicine, Tucson,Az.; Philip A. Brunell,
M.D., '57, Pedatric Infectious Disease,
Los Angeles, Ca. ;Joseph Caprioli, M.D.,
'79, Ophthalmology/Glaucoma, ew
Haven, Ct.; Antonino Catanzaro, M.D.,
'65, Pulmonary and Critical Care Medicine, San Diego, Ca.; Carl I. Cohen,
M.D., '71 , Geriatric Psychiatry, Brooklyn , .Y.; David Cohen, M.D., '89,
ephrology, ew York, .Y.; Michael

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E. Cohen, M.D., '61, Pediatric eurooncology, Buffalo, .Y.; D. ]. Coleman,
M.D., '60, OphthalmologyNitreo-Retinal Surgery, Haworth, .]. ; Bruce F.
Connell, M.D., '52, Facial Aesthetic Surgery, Santa Ana, Ca.; David R. Dantzker,
M.D. , '67, Pulmonary and Critical Care
Medicine, Roslyn, .Y.
Also, Raymond]. Dattwyler, M.D. ,
'73, Infectious Diseases/Clinical Immunology, Stony Brook, .Y.; Patricia
Duffner, M.D., '72, Pediatric eurooncology, Buffalo, .Y.; Demetrius Ellis,
M.D., '73, Pediatric ephrology, Pittsburgh, Pa.; Eugene S. Flamm, M.D., '62,
Vascular eurosurgery, Philadelphia,
Pa.; John F . Foley,
M.D. , ' 55 , Medical
Oncology/Hematology, Omaha, e.; Richard R. Gacek, M.D. ,
'56, Otology/ eurotology, Syracuse, .Y.;
Robert E.Jordon, M.D.,
'65, Dermatology/Cutaneous Immunology,
Houston, Tx.; Louis
Kavoussi , M.D ., '83 , U rology/
Endourology, Baltimore, Md.; Douglas
W . Klotch , M.D. , '71 , Head and eck
Surgery, Tampa, Fl. ; Thomas ]. Lawley,
M.D., '72, Dermatology/Cutaneous Immunology, Atlanta, Ga.; Richard ].
Lederman, M.D., '66, eurology/Electromyography, Cleveland, Oh.; Stephen
R. Marder, M.D., '71 , Psychiatry/Psychopharmacology, Los Angeles, Ca.;
James R. Miller, M.D., '79, eurology/
Infectious and Demyelinating Diseases,
Skaneateles, .Y.
Also, Stan ley L. Olinick, M.D., '40,
Psychiatry/Psychoanalysis, Washington,
D.C. ; Linda Paradowski, M.D., '80, Pulmonary and Critical Care Medicine,
Chapel Hill, .C.; Donald Pinkel, M.D. ,
'51 , Pediatric Hematology/Oncology,
Houston, Tx.;Anthony A. Portale, M.D.,
'74, Pediatric ephrology, San Fran-

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cisco, Ca.; Cary Amet Present, M.D. ,
'66, Medical Oncology/Hematology, Los
Angeles, Ca.; Linda Rabinowitz, M.D.,
'82, Pediatric Dermatology, Milwaukee,
Wi.; Robert E. Reisman, M.D., '56, Allergy and Immunology, Williamsville,
.Y.; Hugh A. Sampson, M.D. , '75, Allergy and Immunology, Baltimore, Md.;
elson B. Schiller, M.D., '66, Cardiology, San Francisco, Ca.; John B.
Schlaerth, M .D. , '68, Gynecologic
Oncology, Los Angeles, Ca.; Max A.
Schneider, M.D., '49, Addiction Medicine, Orange, Ca.; Arthur Skarin, M.D.,
'61 , Medical Oncology/Hematology ,
Boston, Ma.; Kenneth Solomon, M.D. ,
'71 , (deceased), Geriatric Psychiatry, St.
Louis, Mo.; Paul Stanger, M.D. , '61 , Pediatric Cardiology, San Francisco, Ca.;
Morton A. Stenchever, M.D. , '56, Reproductive Surgery, Seattle, W a.; Robert C. Stern, M .D., '82, Pediatric
Pulmonology, Cleveland, Oh.; Virginia
P. Sybert, M.D., '74, Pediatric Dermatology, Seattle, Wa.; Stanley]. Szefler, M.D.,
'75, Allergy and Immunology, Denver,
Co. ; and Lawrence W . Way, M.D. , '59,
Gastroenterologic Surgery, San Francisco, Ca.
+

Medical school receives gift to
create student scholarship fund
he School of Medicine and Biomedical Sciences has received a
$508,000 gift from a trust created
by Helen Hekimian.
The gift will be used to fund
scholarships for students demonstrating academic merit and financial
need.
Helen Hekimian was the daughter of
the late W illiam Crosby, a prominent
Buffalo businessman active in university affairs earlier in this century. She
married Ivan Hekimian, M.D., a 1927

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�..... .... .. ...... .... .. .. .. .. .... ..... ..... ... ... .. ... ... .... .... . r-------------.

NEW
OPPORTUNITIES
FOR FAMILY
PRACTITIONERS
Hassanali, who practices dermatologic cosmetic surgery, originally had
planned to fly to Sarajevo, Bosnia/
Hercegovina, but was turned back. Instead, his group traveled to Zagreb, visiting the main hospitals and rehabilitation centers that house many refugees
and war-injured patients. Hassanali,
himself a refugee from Uganda, donated
$30,000 worth of medical supplies to
the Zagreb hospitals and rehabilitation
centers.
Hassanali plans to bring one 17-yearold patient to Buffalo for reconstructive
surgery. The girl, injured in an explosion in which she lost both parents,
suffered severe burns on her face and
hands.
+

graduate of the medical school who
founded the local Red Cross Regional
Blood Program, taught at the medical
school and maintained an active practice in Buffalo.
+

Time to renew James Platt
White Society memberships

r,

he Jomes Plott While Society - ooiSiinguished
leodersh~ orgonizotion bosed on the values ond
principo~ of the former deon ond founder of the
School of Medicine ond Biomedicol Sciences4 ~ is oleoding suppporter of the school'smission of
providing the highest quorlly educofion, reseorch ond ~
lient core.
Through its membels' generous, choritoble member·
ship pledges, the School of Medicine ond BiomeOICol
Sciences confinues its leodel5hip role os one of the premier
medico! schoo~ in the counhy-one poised to reoctto the
dxJIIenges of heolth core refonn ond the burgeoning
technology revolution through the use of innovative educooonol ond orgonizofionol progroms !hot benefit the next
generotion of both physicions ond their potients.
nyou hoven'tolreody, pleose renew your membership
pledge for this yeor.And fyou oren'tolreody omember, but
would like to join the medico! school'sprincipol supporting
orgonizotion, pleose coli Michoel E. Benzin, Director of the
Annuol Appeol, ot (716) 64 5-3312.
+

ynette ieman, M.D., ' 78, has
been appointed clinical director of the ational Institute of
Child Health and Human Development.
She has served as deputy
clinical director of the agency since
1990, and more recently as acting
clinical director. Board certified in
internal medicine , endocrinology
and metabolism, Nieman has served
on the institute's IRB since 1988 and
on a number of clinical center committees focused on issues of patient
care. She has been an invited speaker
at many symposia and grand rounds ,
and has offered testimony concerning RU 486 to Congress on a number
of occasions. Nieman's research has
focused on attempts to improve diagnostic precision in Cushing's syndrome , the evaluation ofluteal function and the uses of antiprogestins
in the reproductive cycle.
+

iyaz Hassanali, M.D., '86, recently
returned from a humanitarian
mission to Zagreb, Croatia, he coordinated to bring medical supplies and drugs to refugees of the
war in Bosnia.

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W e provide everything you
need to build a successful
practice, as well as an
enriching work environment.
Salary is highly competitive.
Benefits include retirement
plan , license fees, health and
malpractice insurance, ample
vacation and CME time, and
research opportunities. Area is
eligible for loan forgiveness
programs. Call coverage is
very good and is managed
effectively. Managed care
programs are already in place.

Lynette Nieman '78,appointed
clinical director of NICHD

ftiyazHassanali '86,spearbeads
humanitarian mission to Zagreb

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BEIBC family practitioners
needed to staff new family care
sites to be opened by ECMC
and SUNY at Buffalo
Department of Family
Medicine.

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Responsibilities include
clinical work and teaching of
residents and medical students.
Administrative duties are
flexible. Physicians must be
willing to perform obstetrics.
(With in-house OB back-up.)
Please contact Rebecca
Brierley, Family Medicine
Recruitment Coordinator,
Erie County Medical Center,
462 Grider Street, Buffalo,
NY 14215, (7 16) 898-4797,
fax (716) 898-4750.

ERIE COUNTY

~fMEDICAL CENTER

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MUSINGS ON THE WAY TO

of

©

Humor

L.A .

finally bought myself a new car. First time! I had always avoided it for fear
of having to bargain with the salespeople. But first, of course, you have
to deal with the receptionist. I called and said, ''I'm looking for
Michael," and she asked, "Is that a two-door or a four-door?"
The salespeople always want to know
your last name, so they can repeat it over
and over to lure you into a feeling of
false security. When I was looking I
always told them my last name was" o
Sale Today."
"Will you be buying the car today,
Mr. o Sale Today?"
" o! And that's Dr. o Sale Today."
That's not true. I would never tell
these guys I'm a doctor. Then they'd see
me as a six-foot chicken on a rotisserie.
I decided to take a trip down to L.A.
to break the car in and visit a friend . I
had a lot of time during the drive to
think about things, not the least of which
were the present inhabitants of the White
House - two lawyers. I liked it better
when we had an actor, a diet pill addict
and Frank Sinatra doing naked pushups in the Lincoln Bedroom. At least
you knew what you were dealing with
and they entertained you all the time.
As I got closer to L.A. (you can always tell from the lovely red haze in the
air) I called ahead to let my friend know
that I would be there in a half hour. I was
only two miles away, but this was L.A.

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Great times we live in- to be able to
make calls from the highway - and I'm
thinking, "Wow! I'vegotacellularphone
in the car," which means I no longer
have to stop at a gas station to make
phone calls. ow if they could come up
with a cellular toilet, that would be
great.
Cellular phones are still somewhat
affordable - especially if you only use
them on weekends. I try to avoid the
"airphones," though. On a recent flight
they announced a contest: make a call
on the airphone using your credit card,
and you have a chance to win $50,000
-or spend $50,000 if you stay on more
than 10 minutes.
Before arriving at my friend's house I
decided to pick up a bottle of wine. I
handed the clerk a 20 bill and he placed
it under the drawer. I thought, "Why do
they place the $20 under the drawer?"
That's the first place a hold-up artist is
going to look ... unless he's stupid. What
are we dealing with here - remedial
criminals? "Gee, all I see are ones and
pennies . . . where could the big bills
possibly be?"

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.

I also glanced through People magaThat day, the headline of the newspaper (well not the newspaper - USA zine. They had a quiz titled "Are you a
Today) said that Congress was hoping genius?" You can pretty much be sure
to pass a bill that would ban all assault that if you're reading People magazine
weapons. I thought, "well let's see, we've and taking that test - you're not ...
got Uzis, AK 4 7s, HMOs and grenades." although I did score pretty high.
When l finally got to LA. , one of the
Kaiser Permanente is big in Sou them
first
things my friend and his wife asked
California. I believe one-third of the
me
was
how to choose the right doctor.
insured population there is with Kaiser.
This, in fact, is the model the govern- With the new government health plan
ment is following. In order to keep pace looming on the horizon, many people,
I heard that Kaiser is thinking of install- including your friends and relatives,
ing an outpatient drive-thru window. will be asking you for the same advice.
Having recently faced this many times
First in the country, in fact.
myself, I never know what to say, but do
offer to tell people how not to choose
the "wrong" doctor. I've even prepared
a little handout. Feel free to copy it and
do the same.
Tips on Choosing Your Doctor
• Do not choose a doctor whose office
is on a Greyhound bus.
• It is probably not a good sign if for
every prescription of Prozac your docThe sports page announced that
tor writes, he gets 100 frequent flyer
Darryl Strawberry signed with the Gimiles.
ants. Yeah, I suppose if he gets in shape
• If he says, "OK, up on the table and
he can lead the league in free-basing.
take off my clothes." Stay away! !!
And for you real couch potatoes who
• Watch out if he keeps referring to his
can't program a VCR, now there's a new
stethoscope as Hector.
device that allows you to command
• Ladies, it is not good if there is a sign
your VCR. You just lie there on the
on the wall that reads, " o Shoes. No
couch and say, "Tape Seinfeld. Channel
Shirt. No Cervix."
4. 8:30." and it will do it for you. The
• Be careful if the fish tank in the waitdeluxe version has an additional feature
ing room is labeled "Exhibit A."
that lets you say the words, "I have no
• Most importantly, leave his office
life," and it lifts your skull off and sucks
immediately if he asks you to turn your
out your brain and you become a huhead and pull his finger.
+
man futon.
And apparently Bill Clinton cel- Stu Silverstein, M.D., president of Stondup Medicine Seminofl ci Son fmncisco,
ebrated his SOOth day in office by gain- Colifomio, ledures notioowide on hun101 in med"Kine. He recently published his
first book, What About Me?, about growing up with a developmentnDy
ing his SOOth pound .
tfiSObled sibling, c~H~Uthored with BfYTKI Siegel, Ph.D.

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Tran fers arranged \vithout loss.

(71 6) 856-1234
EXTENSION 6142

ACADEMIC HEALTH
PROFESSIONALS
INsURANCE AssociATION

has
been elected president of the William A. Little Obstetrical and Gynecological ociety, the association of faculty and alumni of the
Department of OB-GYN at the
University of Miami(Jackson Memorial Medical Center. It is of

a

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Complete legal service
~

RAPHAEL 5 . GOOD '48,

u

of Meeting Space

~

~

writes, "Five years after closing
my private practice, I am again
retiring, this time as medical director of a preferred provider organization. Our plans are to spend
more time with children and grandchildren, distributed on the east
and west coasts, but Youngstown,
ew York remains our home."

B

18,000 Square F eet

Comprehensive coverage

grandchildren and one greatgrandchild, Helen (Tweet) and I
are looking forward to celebrating our Golden Wedding Anniversary, both of us in good health.
We hope the other newlyweds of
June 1944 will celebrate their anniversary with joy also."
WILLIAM

~

Rewarding educational programs

HYATT.
WE'VE THOUGHT OF

EVERYTHING~

Empire State Building
350 Fifth Avenue, Suite #1512
ew York, ew York 10118
Ph. 212-947-4541
Fax 212-947-4572

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~- -~-

'

particular note that Dr. Good is
a past president of the South

He is a fellow of the American

Florida Psychiatric Society.

president of the Georgia Psychi-

I

Psychiatric Association and past
atric Physicians Association. Dr.

9

5

0

'51 ,

Haberman is clinical associate
professor of psychiatry at Emory

received the degree of Doctor of
Science, Honoris Causa on May

and Morehouse University

1

EDWARD SHANBROM

5

University School of Medicine
School of Medicine.

22, 1994, from Allegheny College. Dr. Shanbrom has published over 100 scientific articles

D IANE

and is the author or co-author of
over 20 patents. In the 1960s he
collaborated with Dr. Kenneth
Brinkhous to establish a technique that allowed concentration and purification of factor
VIII. Besides funding scientific
endeavors, Dr. Shanbrom and

his wife, Helen, have also been
supporters of the arts and education in their Orange County,
California community.
HILLIARD JASON

' 58 ,

has

hosted, co-written, and produced more than 50 educational
videos in the field of medical
education for national distribution. Springer Publishing Company has recently released a new
book written by Dr. Jason and
his wife (Jane Westberg, Ph.D.)
titled: Teaching Creatively with
Video: Fostering Reflection, Communication and Other Clinical
Skills. Both this new book and a

prior book, Collaborative Clinical Education: The Foundation of
Eff ective Health Care, are part of
the Springer Series on Medical
Education.
is
now retired, after practicing general surgery in ew Mexico since

deputy director, Community
Health Surveillance within the
Maryland Department of Health
and Mental Hygiene. Earned my
MPH at Johns Hopkins University School of Hygiene and Public Health and am board certified in general preventive medi-

Hilt.ard Jason '58
1971. Dr. Wilbee was recently
appointed to membership on the
State Board of Medical Examiners. He is a former president of
the State Medical Society and
past president of the
ew
Mexico chapter of the American
College of Surgeons.

1

9

JOHN

6

0

JOHN C . S T UBENBORD '75,

has been practicing internal
medicine and family medicine
in East Aurora for 10 years. He

5

was appointed a fellow of the
Royal Society of Medicine, London, in July 1992. He has three
boys, Derek, 6, jess, 3 and
Wesley, l.

SHIELDS '68, of
ew York, is medical

E.

Delphi,

director of Bassett Health Care
of Stamford-Delhi. Dr. Shields
is a member of the American
College of Physician Executives.

1

7

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0

5

GEORGE Y . LOHMANN , JR.

'72 , is listed in Compton-

Connally Guide to Best Doctors
in ew York Metro Area, Who's
Who in the East, Science and Engineering and World, Business
and Finance. His daughter,

orelle Christa Victoria, was
born October 15, 1991.

u

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MICHAE L A . HABERMAN 73,

u

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ROBERT J . BRACO '80, of
Springfield, Missouri, has joined

the Springfield Clinic to do in-

PAB LO

RODR I G UEZ

' 81 ,

writes, "I have been awarded the
'Community Service Award' by
the AMA young physician section for my work with the Minority Health Advisory Committee to the Rhode Island Department of Health. I have two boys,
ages 3 and 5; my wife and I have
become avid windsurfers."

University and is practicing with

term. His 7-year-old son, Keith,

Kaiser in Fontana, California. She

won first place in the National
Radiant Peace Foundation's essay contest for the Midwest region. Besides a cash award, his

is an associate GI fellowship director and assistant clinical professor of medicine at Lorna linda
University. She and her husband,

essay will be considered for publication in a book about children
and their contribution to world
peace.

Chiayu Chen, have a daughter,
Katherine, born January 17,
1993.

Medical Association of Atlanta.

h

1

RONALD A . V IDAL 77, was
elected president of the medical
staff of Samaritan Health System
of Clinton, Iowa, for the '94-'95

was installed as president of the

p

Ronald A. Vidal '77

dustrial consulting.

cine and public health."

ROBERT H . WILBEE '59,

B

L. MAT USZAK '74 ,

writes, "Recently appointed

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PAT RICIA HSIA '85, completed
a GI fellowship at Georgetown

NIC HOLAS D 'A V ANZ O '86, is
practicing pediatrics in a [ourman group in Raleigh, orth

n

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. .. .. . ... . ... . .......................... . ....... . ... .. ....

I

Peggy Morey
Stager '88, was
married October
30th to Richard
Stager.

Carolina. He and his wife have two children, Stephen icholas, 10 months and a 3
V2-year-old daughter.

1

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FAITH F R ANK E L '91 , completed apediatric residency at Georgetown University Hospital and is now in private practice in Virgm ta. She and her husband, Douglas

'88, was married October 30th to Richard Stager. Friends
PEGGY MOREY STAGER

Power Mac 7100 includes:
• 15" Color Monitor
• ClarisWorks
• CD ROM Bonus:
Microsoft Bookshelf

Frankel, M.D., have a 1-year-old son, Maxwell Shane Frankel.

from near and far joined the special celebration at the Buffalo Hyatt Regency. Mary
Davitt and Mitch Tublin arrived from Pittsburgh, Nancy Lisch cruised in from Cleveland, and Cindy and Tom Bellomo road
tripped from Milwaukee. The local attendees included Lori and Frank Luzi, Lisa
Benson and Lee Guterman ('89) and Helen
and Andy Cappucino. A fantastic time was
had by all! The newlyweds reside in Cleveland Heights, Ohio. Peggy is an adolescent
medicine attending at MetroHealth Medical Center.

C

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66 MHz, PowerPC 601 RISC-based processor, 8MB
RAM, 250MB hard drive. Macintosh Color 15" display,
AppleDesign keyboard, built-in Ethernet, at:ive
ClarisWorks 2.1, and the Apple Student Resoun:e Set
which includes: The Macintosh Writing Companion;
Student Assist; The Internet; Microsoft Bookshelf; The
Voyager Offer (a coupon offer to pun:hase interactive
CD ROM discs for just $9.95 (normally sold for $24.95
to $79.95)).

( LEBER MAN )
JENSON

' 92 ,

writes, "Curren tly
co mple ting fi rst
year of anesthesiology residency at the
University of Pittsburgh . Mark and I
are celebrating our one year anniversary,
May 15, 1994."

MI.L.

$2358
• 15" Color Monitor
• Pentium Upgradeable

THOMA S GRIMAL DI '89, writes, ''I'm com-

OBITUARIES

pleting urology training at the University
of Michigan and plan on joining the UB
Urology faculty at the Buffalo VA Medical
Center. My 1-year-old daughter, Sarah, and
I are coping with the death of my wife,
Ester Ponce Grimaldi '89. Thank you classmates for all the support. Ester died suddenly in an automobile accident injanuary
1994. A medical school graduation award
is being established in her name, to recognize a compassionate and positive approach
to clinical medicine."

8

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66 MHz 486DX processor, 8MB RAM, 340MB hard
drive, SVGA 15" color monitor, 3.5" floppy drive, full
size keyboard, DELL System mouse, DOS 6.2 .
Windows 3.1, and 1 year next business day on-site
service.

died on March
23, 1994, in Buffalo. Before retiring in 1985,
he practiced internal medicine and was
associated with Millard Fillmore Hospital.
After retiring, he and his wife, Lois, spent
winters in Florida, where he enjoyed fishing and golfing.
RUSSELLS. K I DDER '41 ,

KENNET H

SOLOMON '7 1 ,

• Apple • IBM • Dell • Compaq
• Panasonic • Hewlett Packard
• TI • Sony • Software
• Supplies • Accessories • Audio
• Hands-on Workshops

died unex-

pectedly last spring.

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�BUFFALO PHYSICIAN
STATE UNIVERSITY OF NEW YORK AT BUFFALO

3435 MAIN STREET
BUFFALO NEW YORK 14214

Non-Profit Org.
U.S. Postage
PAID
Buffalo, NY
Permit No. 311

ADDRESS CORRECTI O N REQUESTED

1773

EALTH SCIE CES
SE
LS DEPT
ABBOTT HALL
CAMPUS
IL
4

The only liability coverage
with this seal of approvaL
Medical Liability Mutual Insurance
Company (MLMIC) is the only professional
liability insurer approved by the Medical
Society of the State of ew York.
Since its founding in 1975, the phy icianowned and managed company has successfully defended more physicians than all
other available insurers combined.
Additionally, MLMIC has the largest
and most experienced professional liability claims department in the country, the
large t risk management department of
any ew York State professional liability
insurer, and the state's only true peer
review of claims experience.
Call1-800-ASK-MLMIC (metro) or
1-800-356-4056 (upstate) for more information and an application.

MLM~C
~
Medical Liability
Mutual Insurance Company

Our defense never rests.

2 Park Ave., New York, NY 10016
2 Clinton Sq., Syracuse, NY 13202
90 Merrick Ave., East Meadow, NY 11554
tO 1993 Medical Liability Mutual Insurance Company

--Oo&lt;- M--Oo&lt;

��\

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~ach
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year, the University at

Buffalo School of Medicine
and Biomedical Sciences ad,
mits 135 new students.

I

Over the next four years,

I
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they will learn both the art
and science of medicine as
they realize their calling and
form lasting relationships that
will enrich their lives.

J

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Here, Buffalo Physician pre,

I
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sents the Class of 1998 and
wishes them well on this, the
beginning of their four,year
journey to become physicians.

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LUNA BAilEY

LESliE BARR

Duke Uniwrsity

L:nn·ersity 1t Bufralo

Bzology/Chemmry

Psychology

Bwlo~·

LORI BOWMAN
SU. 'r J.t Geneseo

RICHARD BREMER
Clarkson UniversitY

Bwlogy

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YVONNE BOBEK
Cornell Uni\·ersit~

• · · · ·· · · · · · ·· ·· · · · · · · · ·· · · · · ·· · ·

ERIC BONENBERGER
orth Carolma State University

Bzology

:oology

STEPHEN BEKANICH
,j Scranton

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ROBERT BURNS

TERRI CAliGIURI

EMilY CAlKINS

Gannon Umver&gt;~t\

Gannon lJmveut~

UniversitY at Buffalo

Biology

Biology

Anthropology

APRil CAMPBEll

JOHN CARTER

CAROl CHEN

Princeton Lmversity

SU Y at Plattsburgh

Johns Hopkim University

CONNIE CHEN
Cooper Union

History

Biology

Biology

Elecmcal Engmeering

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ew York Universtty

PETER COBB
Davidson College

SETH COHEN
Yeshiva Umversity

JEANINE COOLEY
Umversity at Buffalo

Biology

Biology

Biology

Health Sc1ences

PAM CROWELL
Mercyhurst College
Sports Med1cme

MICHAEL CUMMINGS
Cornell Umversity

GUL DADLANI
Umversity at Buffalo

JONATHAN DANIELS
University at Buffalo

Nurririon

Biology

Psychology

CHRIS DEAKIN
Umversity at Buffalo

MARYANN DEAN
West Liberty State College

BARBARA DEGUISEPPE
Saint Francis College

CLAUOIA DEYOUNG
Northeastern University

Busmess

Art/Psychology

Biology

Mechanical Engineering

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New York Umversity

STACEY DIMARTINO
Universit} of Rochetser

VAMIL DIVAN
University of Pennsylvania

JANE DOPKINS
Harvard-Radel iffe

Policies

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Women's Studies

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CRYSTAL DYER

JASON EHRLICH

ANDREW ESCH

Colgate University

CUNY City College

Umvemty at Buffalo

Universitv at Buffalo

Bwlogy

History

Busmess Admmistranon

eurosCience

JOHN FANTON

TODD FEHNIGER

CHARLES FETTERMAN

MELISSA GARDNER

SU Y at Binghamton

Uni,·ers1ty at Buffalo

Cams1us College

Hartwick College

Philosophy and Bwlogy

Bwlogy

Biology

Psychology

RICHARD GAYlE

JENNIFER GEORGE

THOMAS GERGEL

ROBERT GERSTENBLUTH

Cams1us College

Fordham Univer ity

University at Buffalo

Biology

Chemistry

Biology

U

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Bwlogy

YOUSSEF GHAL Y

HARI GOPAL

CHRISTINE GORDON

LISA GREEN

CU Y Queens College

Cornell Umvemty

CUNY Lehman

UniverSlty of Rochester

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Anthropology

Cell and Developmental Biology

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PETER JANES

THERESA JARMUZ

LAWRENCE KANNER

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LORI KWAN

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TOM MALINICH

MICHELLE MANG

Bucknell University

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PENELOPE MARTIN

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GEORGE MOYNIHAN

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JENNY OH

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Univers1ty or Notre Dame

Tufts University

Johns Hopkms Umverstty

University at Buffalo

Business Administranon

Psychology

Biology

Physical Anthropology

PRASHANT PARASHURAMA
Cornell Umvers1ty
Phys1cs

VIRESH PATEl
Umvers1ty at Buffalo

NICOlE PAZZAGLINI
Umvemty at Buffalo
Anthropology

Johns Hopkms Un1versity

Chemical Engineering

ACHINI PERERA

Biology

ClAYTON POlOWY

COLIN POWERS

JOSEPH REBHAN

JAMES REUTHER

M1am1 Univer-ity of Ohw

Cams1u College

SU Y at Plattsburgh

M1ch1gan State

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Biochemistry

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ANNE MARIE REYNOlDS
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Lawrence University

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ANTHONY RICE

JEFFREY RICHMAN

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Cams1us College

Worcester Polytechmc Institute

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Queen's University

ZULMA ROSADO
UniYersity at Buffalo

Boston Umverstty

Life Sctences

Biology

Biomedical Engineering

JENNIFER SCAROZZA
Canisius College
Biochemistry

CHRISTOPHER SCHAEFFER
Harvard Umversity
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University at Buffalo

ANGELA SCHOEP
St. Olaf College

Psychology

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Miami University ofOhw

Mtchtgan tate Univer ity

JOEL SEBASTIEN
D'Youville College

CARL SEON
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University at Buffalo

MACDUFF SHEEHY
Brown Umverstty

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Lehigh University

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                    <text>State University of New York at Buffalo School of Medicine and Biomedical Sciences, Summer 1995

�BUFFALO PHYSICIAN

Volume 29, Number 3
STATE UNIVERSITY OF
NEW YORK AT BUFFALO
SCHOOL OF MEDICINE
AND BIOMEDICAL
SCIENCES

Dr. john a ugh ton, Vice President
for Clinical AffalfS, Dean
ASSOCIATE VICE
PRESIDENT FOR
UNIVERSITY SERVICES

Dr. Carole Smtth Petro
DIRECTOR OF
PUBLICATIONS

Timothy j. Conroy
EDITOR
Nanette Tramont, R.
ART DIRECTOR

Alan j. Kegler
ASSOCIATE ART DIRECTOR

DaVId j. Riley
PUBLICATIONS MANAGER

Dear Alumni and Friends,

T

his issue of Buffalo Physician highlights selected efforts in the national and international
arena of volunteerism in which many faculty and students engage. You are probably
already aware that foreign exchanges designed to enhance research and educational
endeavors have long been a tradition for the school's faculty. Humanitarian efforts toward
aiding the citizens of the global community take that tradition one step further. As the world
becomes "smaller," it is even more important for UB's faculty to develop meaningful
relationships that serve to enhance humanitarian efforts throughout the
world.
UB obviously offers a fine environment in which to train physicians
and scientists from here and abroad, and its faculty and students have
endeavored to "give back"- both to their local and global communities
- a measure of what they have received. In all the exchanges, both the
giver and the rec1pient benefit. We have many examples of successful
exchanges in Europe and Asia, as well as in our own community.
lam sure these will continue in the years ahead and that more will
be added as national and international collaborations increase, and
more physicians become aware of the needs for such humanitarian efforts.
Sincerely,

judson Mead
PRODUCTION MANAGER
Ann Raszmann Bro\vn
EDITORIAL BOARD

Dr. john A. Rtchert, Chairman
Dr. Marttn Brecher
Dr. Harold Brody
Dr. Rtchard L Collins

john aughton, M.D.
Vice President for Clinical Affairs
Dean, School of Medicine and Biomedical Sciences

Mr. Ravi Desai

Dr. Alanj. Drinnan
Dr. james Kanskt
Dr. Elizabeth Olmsted
Dr. Barbara MaJeront
Dr. Charles Paganelli
Dr. Margaret W. Paroski
Dr. Thomas Raab
Dr. Robert E. ReiSman
Dr. Stephen Spauldmg
Dr. Bradley T. Truax
TEACHING HOSPITALS AND
LIAISONS

The Buffalo General llospttal
\fichael Shaw
Buffalo VA Medical Center
Arlene Kelly
The Chtldren's Hospttal of Buffalo
[ne County Medtcal Center
Mercy Hospttal
Mtllard Fillmore Hospttals
Franll Sa\·a

Roswell Park Cancer lnstttute
Sisters of Charity llospttal
Demus McCar·thy
©The State Umvcrstty of New York
at Buffalo

Bufftdo Physician is publtshed
quarterly by the State University of
'lew York at Buffalo School of
Medicme and BIOmedical Sctences
and the Office of PublicatiOns. It is
sent, free of charge, to alumni, faculty,
students, residents and friends. The
staff reserves the right to edtt all copy
and submiSSIOns accepted for
publication.
Address questions, comments and
submiSsions to: Editor, Buffalo
Phystcian, State University of New
York at Buffalo, UniverSity
Publications, 136 CroftS Hall, Buffalo,
cw York 14260

Send address changes to:

Buffalo
PltysiCian, 147 CFS Addttion, 3435
Matn Street, Buffalo, New York 14214

Dear Fellow Alumni,

T

hank you for the opportunity to serve as President of your Medical Alumni Board of
Directors. My predecessor, Dr. Russell Bessette, did an outstanding job and will be a
tough act to follow. This coming year, 1996, will mark the Sesquicentennial
Anniversary of the medical school. Celebration of this event has already begun, with
the conferral of an honorary degree to Dr. Gregory Thorn, one of our most distinguished
alumni, at the medical school commencement this year. We will also be publishing an
updated Medical Alumni Directory, which will include a brief history
of our medical school. We hope you will take advantage of this
directory to keep in touch with o ld friends.
Plans for the 1996 Spring Clinical Day are already under way. Dr.
Beth Maher is planning a promising program addressing issues on
death and dying. The Alumni Association will continue to sponsor a
wid e range of activities for the medical students, including the
Community Physician Program, the Senior Reception and orientation events. This past year we donated funds to furnish the medical
student lounge.
We look forward to a busy and enjoyable year, and hope we can count on your support.
We're always looking for new ways to serve our alumni and welcome your suggestions.
Sincerely,

Margaret W. Paroski , M.D. '80

�8
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Research
Hospital News
Partial liquid ventilation. Page 12.

Giving Back e UB's doctors volunteer their skills
and themselves to communities throughout the
world - including their own.

m

Breathing Life Through Liquid e The new technique
of partial liquid ventilation developed at UB has
the potential to revolutionize the treatment of
respiratory failure.

Medical School
Then and Now
, Alumni
ASpoonful of Humor
Classnotes

*

l~e ~lass of

1~~~. ra~e ~l

Robert L. Brown, M.D. '44,
dies after brief illness. Page 23.

�.
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Study shows no increased breast
cancer-electric blanket use risk
re-menopausal women who sleep
under electric blankets do not significantly increase their risk of
developing breast cancer, a study
conducted by UB researchers has
shown.
The research is a follow-up to an earlier UB study involving post-menopausal
women that also found no increased
risk of breast cancer as a result of electric blanket use. It was published in the
December 1994 issue of the American
journal of Epidemiology.

In the current study, a team of researchers led by john Vena, Ph.D., professor of social and preventive medicine, investigated a possible breast cancer-electric blanket association by comparing electric blanket use in 290 premenopausal women who were newly
diagnosed with breast cancer with a
control group of 289 age-matched
women without cancer.
Results showed that among those who
used electric blankets the most, the percentage of women with cancer and without was identical. In both groups, 8.3
percent said they had used a blanket daily
in season and continuously throughout
the night for the previous 10 years.
"The bottom line," Vena said, "is if
there is an effect, it is likely a weak one.
Some researchers now think that the
pineal-melatonin mechanism [one of
the mechanisms suspected to increase
breast cancer risk] may only operate for
certain types of cancer tumors- those
that are estrogen-receptor positive. The
next phase in our research will be to
look at electric blanket use and certain
types of breast cancer."
Also participating in the study werejo
L. Freudenheim, Ph.D.; james R.
Marshall, Ph.D.; Rosemary Laughlin,
Ph.D.; Mya Swanson; and Saxon Graham, Ph.D., all of the department of
social and preventive medicine.
+
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weren't recommending the back position
despite the AAP recommendation. Parents were getting conflicting advice from
nurses and doctors."
Hudak designed the
study to determine how
physicians feltabout the
issue and how their attitudes influenced what
they told parents.
The AAP recommends the tummy-up or side position.
Reasons given most
often for having reservations about the recommendation were
the lack of published data on the connection between sleep position and SIDS in
the U.S., and past experience. Also menUB study has shown that physi- tioned often was the possibility of aspiracians are reluctant to follow the tion after gastroesophageal reflux.
+
recommendation of the American
Academy ofPediatrics and tell parents to put newborn babies on
their backs to sleep to reduce the
risk of Sudden Infant Death Syndrome.
The recommendation, promulgated
by the Academy in 1992, broke with
University at Buffalo study- the
what had been tradition since the 1930s
first ever to assess the use of
and abandoned the practice of placing
assistive devices by elderly perinfants on their stomachs after studies
sons with Alzheimer's disease and
from Europe, Australia and ew Zealand
other cognitive impairments- has
showed a significant decline in SIDS
found most existing devices for
after physicians there urged parents to patients with dementia aren't designed
put their infants to bed on their backs or to remain useful as mental health detesides.
riorates.
The UB study, reported in the january
Results of the study, conducted by
1995 issue of Pediatrics, involved 121 researchers in UB's Rehabilitation Engiprimary care physicians. Only 24.4 per- neering Research Center on Aging,
cent of them said they strongly agreed showed that elderly persons with cogniwith the AAP recommendation and only tive impairments living at home were
42 percent said they recommended the using fewer devices after one year than
supine position to new parents.
at the beginning of the study, even
Principal author Bonnie B. Hudak, though their need for helpful devices
M.D. , assistant professor of pediatrics, had increased due to declining health
undertook the project as a result of her and cognitive status.
own experience with her new daughter.
"Obviously we are not making de"When I had my baby in 1993, no- vices that are as useful as they should
body talked to me about sleep posi- be," said William C. Mann, Ph.D., direction," she said. "I began talking to other tor of the center, professor and chair of
parents and learned that pediatricians the department of occupational therapy

Physicians reluctant to heed ill
adrtce about infant sleep position

Alzheimer'simpairment outpaces
dertces designed to aid patients

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and lead researcher of the study. "We
need to develop more 'smart' devices
and devices that will remain useful
longer, as cognitive health declines. "
Baseline data from the study, reported
at a recent Gerontology Society of
America meeting, came from a Consumer Assessments Study by center researchers that analyzed the types of
assistive devices used by 90 elderly
people and their caregivers. Mann and
his colleagues based their current findings on a 31-person subset- all with
cognitive impairments living in a home
setting. Twenty-five of the 31 were diagnosed with Alzheimer's disease; the
remainder were cognitively impaired.
The researchers intend to follow this
group for five years to provide direction
for new device development and improvement of existing devices.
+

researchers say fractal geom-

l etry may hold the key to ear-

~l

lier detection of osteoporosis.

The computational technique that tests and characa. Ill terizes bone deterioration
more accurately than methods currently
in use was developed by Raj S. Acharya,
Ph.D. , associate professor of electrical
and computer engineering.
He explained that clinicians who look
at X-ray images of bones have only been
able to track deterioration in bone mass;
deterioration in the honeycomb structure has been too subtle to see.
But Acharya and his colleagues found
a way to examine the fragile interconnections in this tissue , and to determine
the level of deterioration. The technique lets them home in on each pixel
in an X-ray or MRl and assign it a
specific value called a fractal dimension.
"With fractal dimensions , we can compute structural information," Acharya
B

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Genetic evidence of smoking and
cancer rtsk shown by UB study

said. "Together, mass and structural
information give a much better indicator of bone condition. "
Working with animal data obtained
from Merck Corp. , Acharya and colleagues from the School ofDental Medicine used fractals to compare the trabecular tissue of the bones of normal rats
with those of rats with osteoporosis
induced through estrogen depletion or
the immobilization of limbs.
"ln both cases, when we computed the
fractal dimension in these data, we found
there was a significant difference between
the values for normal bones and the values for bones with osteoporosis," he said.
In the early stages of osteoporosis, Acharya
said, "the honeycomb structure might
actually be broken, which would weaken
the bone, but because the mass might still
be the same, a bone density test would not
show anything abnormal.
"The advantage of our approach is
that if you can pick up signs of disintegration before the bone starts massive
deterioration, then you can start
therapy ," he said. "And if you can
catch it at an early stage, there's a good
chance that a deeper osteoporosis will
not develop. "
+

Fractal geometry may aid in
earlier detection of osteoporosis

-

B

Y

ELLEN

esearch has yielded further evidence of a genetic link between
cigarette smoking and breast cancer risk in humans. A study conducted by UB scientists has shown
that female smokers who have the
slow-acting genotype for -acetyl-transferase ( AT2) , an enzyme that detoxifies carcinogenic compounds in cigarette smoke, could have eight times the
risk of developing breast cancer as
women with the fast-acting NAT2 gene.
The research provides new insight
into why previous epidemiologic studies may have failed to show a consistent
association between cigarette smoking
and breast cancer in the face of evidence
that tobacco smoke is a cancer risk factor at many other organ sites.
Other research has shown that smokers with the slow-acetylation genotype
for NA T2 had higher levels of tobacco's
carcinogenic compounds in their bloodstream and were at increased risk of
developing bladder cancer.
The UB researchers - led by postdoctoral fellow Christine Ambrosone,
Ph.D., of the department of social and
preventive medicine - analyzed the
characteristics of the AT2 gene in the
DNA of 159 post-menopausal women
with breast cancer and 203 cancer-free
women in a control group. A strong
association between smoking and breast
cancer in slow acetylators was shown,
with women who began smoking before
age 18 at highest risk. Intensity of smoking at two, 10 and 20 years prior to the
interview appeared more significant than
duration of smoking. Slow acetylators
showed a fivefold increase in risk.
No significant associations between
breast cancer risk and total years smoked,
packs-per-average year or pack-years
smoked were demonstrated among rapid
acetylators.
+

GOLDBAUM

Fractal dimension (FD) graphed for spine (above).
e I'Moftsl

FD

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1.90
1.85 •
1.80

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May 30, 1991

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�The nation's first integrated hospice campus combines inpatient care facilities with a 40-bed residential facility containing a 10-bed AIDS unit.

The lO-bed inpatient unit, which replaces Hospice Buffalo's former Alden
facility, provides care for pain and symptom control, respite , and patients in the
final stages of their disease process. The
unit includes accommodations for family members to spend the night.
Mitchell Campus also serves as a training site for medical and nursing students and allied health professionals
and offers community programs on grief,
loss and living with a life-threatening
illness.
+

Hospice opens unique integrated
residential-inpatient facility
he nation's first integrated hospice campus combining residential and inpatient care facilities
opened in Western New York last
April.
Located in Cheektowaga, Hospice Buffalo's Mitchell Campus was designed by the Hospice Association of
Western New York to meet the growing
need for services to help individuals
and families facing advanced illness.
The innovative campus includes
Kresge Residence - the nation's first
hospice-operated skilled nursing facility-a lO-bed inpatient unit, a 200-seat
multidimensional educational center,
non-denominational pastoral care facilities and centralized offices for Hospice home care and administrative staff.
The 40-bed residential S F provides
advanced care to those who have a
skilled nursing need but a limited
caregiving system, or no home in which
to receive care. lt includes a lO-bed unit
for AIDS patients - the only one in
ew York State outside the ew York
City metropolitan area.
Kresge Residence features a comprehensive activities and recreation program, as well as physical therapy, occupational therapy, speech therapy, mental health services and pastoral care.
Hospice support services include medical social work, volunteer support and
bereavement counseling.

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New book names Roswell one of
North America'sbest hospitals
oswell Park Cancer Institute is
one of the "top-rated medical facilities in the United States and
Canada," according to The Best
Hospitals in America, a new book
published by Visible lnk Press.
Written by john Wright and Linda
Sunshine, the book is a comprehensive
guide to the services offered by the most
prestigious medical institutions in orth
America.
Based on physician recommendations, and supported by information
from government sources , professional
and lay publications, patient satisfaction surveys and interviews with hospital officials, the book identifies for
the public those hospitals whose reputation, personnel , basic and clinical
research, treatment modalities and
other special qualities have earned
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them the highest standing in the medical community.
According to the authors, "these are
places to which physicians in other hospitals send their sickest patients - and with
good reason."
Roswell is the only facility in Western
ew York and one of only 27 nationwide to hold the designation of comprehensive cancer center, awarded by the
ational Cancer Institute.
"We are pleased and proud that
Roswell Park has once again been recognized for its exemplary leadership role
in setting the national standards for
cancer care, research and education,"
said Thomas B. Tomasi, M.D., Ph.D.,
president and CEO of Roswell Park. +

Roswell opens dedicated HIVrelated malignancy center
oswell Park Cancer Institute has
opened its Center for HIV -Related
Malignancies to meet the needs of
patients who have cancer as a
result of human immunodeficiency virus infection.
The new center affords patients access to unique therapies, several of which
have been pioneered at Roswell, said
Zale Bernstein, M.D. , center director.
"These patients require specialized
care and unique approaches to help
prevent and treat malignancies and opportunistic infections," Bernstein said.
"As a major cancer center, Roswell Park
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�. . . . .... . . . . . . . . . . . . . . . .... . . .·. . . . . ... . . . . . . . . . ... . [1]
has the facilities, resources and expertise to provide the intensive care these
patients need. "
A 1994 survey by U.S. News and
World Report ranked Roswell among
the best hospitals in the U.S. specializing in treating HIV-infected patients,
based in part on the design , availability and preliminary successes of innovative treatment protocols the cancer
center offers.
Several current protocols use photodynamic therapy, pioneered at Roswell
in the early 1970s. Others use
Interleukin-2 in self-administered doses
to attempt to ameliorate patients compromised immune systems.
"We have recently completed a study
which indicates that this therapy is easily administered with good comfort and
compliance by the patient," explained
Bernstein. In the patients studied to
date, there have been no opportunistic
infections reponed in over 40 months of
accumulated observation.
Bernstein added that Roswell is one of
only three centers in the nation using
monoclonal antibody therapy to treat
malignant lymphoma in HIV-infected
patients. "We have treated over 15 individuals with this therapy and have witnessed good results, " he said.
"We encourage physicians and HIVinfected individuals to look to our treatment protocols as viable approaches to
cancer care," Bernstein said. For more
information on these and other protocols, call the centerat1-800-685-6825. +

the ew York State Department of
Health.
The heart-lung transplant program
completes and complements the alreadyestablished adult cardiac transplantation program in place at The Buffalo
General Hospital, and is supported by
the School of Medicine and Biomedical
Sciences, as is BGH's. Buffalo General
was designated the area's regional adult
heart transplant center in 1986; its lung
transplant program was developed in
the early 1990s. Children's has maintained a working relationship with the
adult program in an ad hoc role .
Children's has had an active cardiac
program for more than 30 years. The
recent recruitment of Eliot Rosenkranz ,
M.D., from the Cleveland Clinic to head
Children's division of cardiovascular
surgery, has intensified the hospital's
program.
"The designation marks a new milestone in Children's Hospital's more than
103-year history," said joseph A.
Ruffolo, president and CEO of
Children's. "It's about saving lives ...
providing the finest pediatric health care
services well below the national cost
level ... tapping new research doors that
enable us to continue looking for better
treatments and cures to heal our children ... and helping to establish new
referral patterns from throughout New
York State for other specialty pediatric
services Children's offers.
"One of the most pleasing aspects of
this approval process was that Western ew York area hospitals, health
insurers, civic leaders and health care
stakeholders showed unconditional
favor for our effort and participated as
supporters," Ruffulo said.
Children's filed its CON injuly 1994.
At that time, pediatric heart and lung
transplantation in New York State was
primarily provided at adult health care
systems in New York City, or at outof-area pediatric medical centers in
Boston, Pittsburgh and Cleveland. +

Children'swins DOH approval for
heart-lung transplant center
he Children's Hospital of Buffalo
announced it has been designated
Western ew York's regional center for pediatric heart-lung transplants with the approval of its
certificate of need application by

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BGH names Salerno chief of its
division of cardiothoracic surgery
he Buffalo General Hospital has
named Tomas A. Salerno, M.D. ,
chief of the division of
cardiothoracic surgery.
Salerno is internationally
known for his research and the
development of the technique of warm
heart surgery. He has been a visiting
professor worldwide , including at BGH
several times in the past.
Salerno earned his medical degree at
McGill University in Montreal, Quebec.
He received his specia lty training at
Montreal ' s
Royal Victoria
Hospital , where
he became chief
resident in general surgery and
then chief resident in cardiovascular and
thoracic surgery.
Salerno served as professor and chairman of cardiothoracic surgery at the
University of Toronto, Ontario, from
1987 until 1992, and head of the division of cardiovascular and thoracic surgery at St. Michael's Hospital in Toronto
until1993.
He was an honorary professor of cardiac surgery at the University of Chieti,
Chieti, Italy, from 1993 until1994.
ln addition, he has been on the surgical staffs of Kingston General Hospital,
Kingston, Ontario; St. Mary's of the Lake
Hospital, Kingston; Montreal Chest
Hospital; Montreal Children's Hospital;
The Toronto Hospital; and Sunnybrook
Health Science Hospital, Toronto.
He is a member of many national and
international societies, and has published more than 500 papers and abstracts. He is the author of an upcoming
book, Warm Heart Surgery.
+

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"IT IS BETTER TO LIGHT ONE CANDLE," says an old proverb, "than to curse the darkness."
Peter, Paul and Mary made a song of that sentiment back in the glory days of social activism. But 1
volunteer service isn't consigned to the memory of the 1960s. Far from it. As dozens of University at 1
Buffalo medical school alumni, faculty and students demonstrate every day, pitching in with talent and
energy always makes a real difference in people's lives.
From the war-ravaged survivors of the Bosnian civil war, to the rebuilding economies of Vietnam :
and the Ukraine, to the mean streets of our own poorest neighborhoods, volunteerism works.
The darkness around us does seem deep, and there are many who would curse it. For these
physicians, though, there just isn't time to lament the state of the world.
There's work to be done.

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From our own baekyard. to loealrs halfway around thr world. tlw nrrd for mrdieal hrlp is strong.

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IN TilE MIDST OF WAR

some of whom, Hassanali notes, hadn't had a break in two
years.
Fifteen doctors were ready to make the trip in May
1994, but the on-again, off-again war broke out anew in
Sarajevo. "The State Department strongly discouraged us
from going," Hassanali said. "It became a dangerous
situation to bring a big delegation."
Hassanali decided to go alone. He went to Zagreb,
Croatia, and joined the United Nations force there as part
of a group of medics. But the fighting in Sarajevo was too
fierce; the UN could get him into the city, but couldn't
guarantee he'd ever make it out. He stayed in Zagreb,
treating some of the nearly half-million refugees who fled
to Croatia.
Meanwhile, Bergs land, who holds dual orwegian and
American citizenship, was able to enter Sarajevo with a
medical company of the orwegian army. He was in
Bosnia for three months, and spent four days in Sarajevo
just after a major shelling of the city's central fruit market
left 120 dead and scores injured .
"To a large extent those patients had been treated
already," Bergsland said. "We basically did more for the
evacuation. President Clinton had sent a plane to take out

Television images of the vicious civil war in the former
Yugoslavia have horrified the world and sparked compassion for the innocent victims of the fighting. An initial
effort in Buffalo to treat some of the wounds of war now
has blossomed into a large-scale initiative for relief medicine and medical training for Bosnia's physicians.
Called International Medical Relief of Western ew
York Inc., the organization includes about 250 volunteer
physicians and has a corporate office and a warehouse for
supplies. Its president is jacob Bergsland, M.D., an assistant professor of surgery at UB medical school; its vice
president is dermatologist Riyaz Hassanali , M.D. '86.
Several other UB-connected physicians serve as officers or
on an advisory board.
The group began after Hassanali was introduced to the
wife of Bosnia's vice president, herself a dermatologist,
who was living in Buffalo with her children. After hearing
her talk about the situation in her country, Hassanali
organized a meeting of local physicians who wanted to
find some way to help. They decided to solicit medical
supplies and organize a trip to relieve the Bosnian doctors,

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some of the victims, and we had to get them from the
hospital to the airport. " That was accomplished , he
said, in armored ambulances accompanied by armed
guards.
He also practiced in his specialty, thoracic surgery, in
the north-central Bosnian city ofTuzla. Now the contacts
that both Bergsland and Hassanali made have grown into
a continuing relationship with physicians at the Tuzla
Medical Center.
"We had decided that bringing humanitarian supplies
was one thing, but the one group that has been completely
ignored is the doctors and nurses, " Hassanali said.
"Every other organization was helping the victims (of
the war) . But we decided that our efforts would go toward
the medical personnel. These are people who are really
making sacrifices .... We started corresponding with some
of the doctors , and found that they were hungry for
knowledge. "
So International Medical Relief started sending medical textbooks and journals, and put together a shipment
of medical instruments.
The group also began an exchange program, sponsoring Bosnian doctors and nurses to come to Buffalo for
intensive training. The first group includes a cardiologist
and a vascular surgeon, as well as three nurses , all training
at The Buffalo General Hospital.
"Bosnia is not a Third World country by any means ,"
Hassanali said. "But because of the war situation, they
have been completely deprived of outside information
and money to continue their research. You have a very
educated group of individuals who are now just starving
intellectually. "
ln addition , teams of Buffalo physicians - one this
summer, one in the fall- are heading for Tuzla to treat
patients and conduct seminars.
ln the past year, Hassanali said, about $100,000 in cash
has been raised through two dinners and two medical
conferences, and about $500 ,000 in equipment has been
donated. "Our long-term goal," he said, "is to set up a

1

cardiac surgery center in Tuzla. "
For Bergsland, pitching in is a matter of supporting
what's right. "The legal government of Bosnia," he said,
"has a policy that's similar to what we have in the United
States: that people should be recognized as individuals
and not as members of some ethnic or religious group.
The Serbs have this terrible policy of ethnic cleansing and
destruction of other people. Fifty years after the Nazis had
similar policies in Germany, now we have it 400 miles to
the south. This is something that we must do something
about. "
"l can completely identify with what they're going
through ," said Hassanali, himself a refugee from Uganda.
"Somebody was there to help me, to lend me a hand, and
now it's my turn to pay back. ... I don't profess changing
humanity. My goal is to make a difference for one person
in this world. lf we all thought that way, the world would
be so much better. "

SEEING ACR&lt;SS BORDERS
lt was a bit of volunteer work on the Caribbean island
of St. Lucia, back in 1976, that set Yale Solomon, M.D. '50,
to thinking about the rest of the world.
Said Solomon, an ophthalmologist in Bay Shore, .Y.:
"Ophthalmology is the type of work that one can do on
kind of a one-shot basis. l realized that you can go in ,
operate and see patients, and leave, and you don't leave a
trail of half-finished work as you might, for example, in
internal medicine. "
A decade later, Solomon was inspired by a friend who
had done similar work in India to go there. "I met the
doctor in charge, and he was very happy to have the help ,"
Solomon said. "I realized that this could be some sort of
ongoing arrangement, that they could use help beyond
just me for a month. "
That realization has grown into Volunteer Eye Surgeons International Ltd. (VESI) , a group of ophthalmologists who volunteer their expertise to serve month-long

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Scott D. Perrapato , M.D., didn't know what to expect
when he went to Vietnam for three weeks in February.
What he found was both totally foreign - and oddly
familiar.
The Ho Chi Minh Medical School, he said, was built in
the late 1960s by the American Medical Association,
when that city was called Saigon. "It hasn't changed a bit
since then," said Perrapato, who serves as an assistant
professor of urology at the University at Buffalo medical
school. "It was like being in a Southern U.S. medical
school in that time. It's a neat place."
Through the Friendship Foundation of American Vietnamese, an Ohio-based group, Perrapato joined a team of
seven physicians on the trip. They made rounds from 7
a.m. to noon each day , then lectured to medical students
all afternoon. "They have a 200-bed, 350-patient urology
hospital," he said. "To work in that kind of environment
is kind of a dream."
The group also traveled to the provincial city of Nah
Trang, where Perrapato worked with the staff urologists
and saw patients. "''d never been in a place so destitute, "
he said, "but the people showed no animosity (toward
the Americans). From the street people to the government people, they were just gracious. I'm told the Vietnamese and Asian people have always been very open,
and they're certainly not materialistic. . .. There, the
families help give care in the hospitals; they're expected
to, and they love doing it. And really , it's a big advantage
to the patient."
Now Perrapato is on the designing board for a new
hospital in ah Trang, making suggestions for what the
facility should include. He's making a return trip in
February, this time with his wife, Tracy, who did her
residency in family practice at UB.
The hard part, Perrapato said, was the re-entry into
American life. "The quality of the doctors and nurses was
exceptional (in Vietnam) , but the constraints weren't

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'KIND OF A DREAM'

residencies in India, Thailand, Java, Liberia, the East
African nation of Djibouti- and now Vietnam, to which
the group has sent eight doctors in the past year, to see
patients and train the staff physicians there.
"We do not go for volume," Solomon said. "I learned in
India that the doctors there are perfectly capable surgeons
and physicians, and do an extraordinary amount of work.
India has 6 million people with cataracts.
"If we send a doctor there every six months , he's not
going to make a dent in it. We teach some basic material
and do operate, but primarily for demonstration purposes.
"It's amazing how many ophthalmologists- both the
young ones before they really start their practices and the
ones in their later years - have an altruistic sense that
they want to go and do something other than sit in their
office and work for money," he said. "They feel they want
to help and use their unique abilities , and here's an
opportunity. "
The Vietnam project includes bringing a young ophthalmologist from that country, a professor at Hanoi
Medical School , to the New York Eye and Ear Infirmary
for training. "He'll go back with books, supplies, and an
awareness of new techniques that they just don't have ,"
Solomon said. "We're sending him back with a lot of
books which he is going to translate into Vietnamese.
They do not have any medical literature that dates after
1970."
VESI makes it easy to volunteer, making all travel and
living arrangements for ophthalmologists who agree to a
month's service overseas. And the benefits work both
ways.
"It's very rewarding for the doctor who does the work ,"
said Solomon, who has cut his own practice in half to
manage the organization.
"You see cases and see things that you would never
have experienced otherwise. The culture, the way people
react to their physician - the whole atmosphere is so
different. In a sense, this is really fun. "

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�r - - - - - • • • • • • • - - - • - - - - • - - • • • • - - • - - - • • - - - • • • • - - - - - - • - • - • - • • • • - • • - .,

The program also involves bringing Ukrainian physicians to Buffalo for training, as well as an initiative to
translate medical textbooks into Ukrainian. Organizers
also are seeking to install a computer system in the central
medical library in L'Viv, which would make it possible for
physicians to teleconference with their colleagues worldwide.
Sirkin's first trip to L'Viv was in june 1994; she took
with her some donated diagnostic and surgical equipment
and supplies. She taught techniques of anesthesia , cataract surgery and lens implant surgery, as well as such
basics as how to use a microscope.
In March of this year she returned to L'Viv. "They seem
to be doing fairly well," she said. "They're starting to adopt
some of the techniques and some of the equipment.
"But it's very difficult, because you're fighting the
political system within the hospital hierarchy , which is
very patriarchal and hierarchical. Ophthalmology is almost entirely a female specialty there. But the administrators are all male, and the ophthalmologists don't always
get their needs met. "

there. There wasn't the paperwork and all the insurance
overtures. I'd never been in that environment, where you
could just practice medicine. "
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niiTI'IN(l CKRAINE GPTO DATE
There's nothing wrong with Ukrainian medicine that
about 25 years of scientific progress won't cure.
That's what Sara R. Sirkin, M.D. '68, an adjunct professor of ophthalmology at the UB medical school, has found
on two trips to the city of L'Viv in that former Soviet
republic .
"They're very competent people," the ophthalmologist
said of her colleagues there. "The difficulty is , their
medicine is still back in the late '60s. The facilities were
built in the '50s and '60s and are very antiquated. They
don't have access to modern medication or equipment,
and they don't have the money to buy these things.
"Much of their medical care, although adequate , is still
very much Third World. We're trying the best we can to
teach them modern techniques in surgery- in my case,
cataract surgery and lens implants. And we're trying to
upgrade their infectious disease control.
"They're very eager to learn, and there's certainly
nothing wrong with their intelligence. It's just that, under
the Soviet system, they haven't had the opportunity to
learn. "
Sirkin went to L'Viv, an ancient city of 1.5 million
people, as part of the American International Health
Alliance, a joint U.S.-Ukraine effort to improve the medical conditions in the former Soviet republics. "There are
churches that go back to the 13th century," she said. "It's
a beautiful city. " The Buffalo connection was engineered
by Myroslaw Hreshchyshyn, M.D. , chair of gynecology
and obstetrics at UB medical school, through the Millard
Fillmore Health System, for which Sirkin is chairman of
the department of ophthalmology.

ON TilE HOME FRONT
It's not only in far-flung locales that the need for quality
medical care is great. In Buffalo , two initiatives are directed at addressing the health needs of the city's poorest
residents.
At Friends of the Night People, a new medical clinic is
open on alternate Tuesday nights for clients of the soup
kitchen . Its proprietors are M. Steven Piver, M.D., clinical
professor of gynecology and obstetrics and a longtime
supporter of the organization, and Bobby]. Abrams, M.D. ,
an emergency physician who serves as a UB clinical
assistant professor at Erie County Medical Center.
The clinic sees about 20 patients a night, said Abrams ,
who had run a similar clinic in Philadelphia, where she

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�r•••••••••••••••••••••••••••·-------------------------------·-·•
morning clinic for men at Buffalo's City Mission. It's
staffed by physicians from Sheehan Hospital, supported
by volunteer medical students and nurses from the ursing Center for the Homeless, a project of the UB School of
ursing.
"We get a wide range of problems," she said. "In the
winter there are a lot of colds and infections. Overall there
are a lot of foot problems, a lot of athlete's foot, really poor
hygiene. A lot of them are on their feet a lot and don't have
good shoes."
Bonham said about 60 medical students are involved
on a rotating basis, doing initial intake, taking histories
and vital signs. They also solicit donations of supplies
from pharmaceutical companies. She said the clinic sees
15 or 20 people on an average winter morning, fewer in
the summer.
The clients, she said, are just people for whom life has
taken a bad turn. "We had one man who came in, he told
me he had a four-year degree. He was an accountant or
something like that. He said he had been promised a job
in Buffalo, but the job didn't pan out and he had gotten his
wallet stolen. He had no ID, and he found himself on the
street with no job and no place to live. He was very
intelligent and well-spoken, and had all this luggage with
him that he had to carry everywhere.
"A lot of times you find people who've just had bad
luck. The patients generally are quite grateful and very
polite. It's actually surprising to some people. There are a
lot of misconceptions about this population. For the most
part, they're not what you might expect. They're younger
than I had expected, for example. Some of the stories you
hear will break your heart.
"We may not have a lot of skills yet, but we do have
time, so we talk to the patients. Often in an office
setting you're on a time limit, but we tell them if they
want to talk, we'll listen. Sometimes what they need most
is a good listener."
+

served an emergency medicine residency.
"As a physician you have to give back something to the
community, and probably the best thing you can give
back is your skills," Abrams said. "The minute I started
this clinic, I can't tell you how many physicians came,
asking if they could be a part of it. And the medical
students are very eager to volunteer. We can offer them
one-on-one teaching there, and it also exposes students to
working in the community."
Abrams and Piver, with the assistance of medical
students, physician assistants and sometimes volunteer
paramedics, see patients with such complaints as infections, coughs or colds, and perform routine physical
exams. "We don't do anything invasive," she notes- no
needles or scalpels - and they refer plenty of cases to
hospital emergency departments.
"There are whole families that are homeless," Abrams
said. "A lot of my patients are a mother, a father and three
kids. They have no way to get to a doctor and have basic
things done. The kid may have a wound that's almost
infected, but many of them are working people. To sit in
the emergency room for three hours for a kid to be seenthey can't do it."
Part of the job is building trust with patients. Abrams
tells of one man who suffers with a seizure disorder that
began when his father hit him in the head - with a
hammer. The man was institutionalized for 40 years,
she said, and "he was terrified, just terrified. Every time
I saw him, his question was , 'Are you going to put me
back in?' But now he'll come to me voluntarily, looking
for help.
"These people are really going out of their way to be
good patients and help themselves," Abrams said. "And
many of them have said: 'We know you don't have to be
here. Thank you."'
Adrienne D. Bonham is a second-year student at UB
medical school who coordinates Hope Clinic, a Saturday

HPrP in Buffalo. llw JXXlr and llw honwiPss swk medital altPntion at FriPnds of llw ~ight PP&lt;lpiP and llw City Mission.

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�CORINNE LEACH, M . D ., PH.D., HOLDS FOUR-MONTH OLD KENNETH LA BARGE, ONE OF T H E BABIES WHOSE LIVES WERE SAVED BY PARTIAL LIQUID VENTILATION.

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�DuRING THE PAST

DECADE, the University at Buffalo has grown strong among

major medical research centers. Funding has increased, a state-of-the-art research
center has recently been built, and the reputation of UB investigators continues to
develop. But all this pales by comparison with the thousands of lives that will be
saved as the work of these researchers becomes clinical reality. From the tiniest of
premature infants to elderly victims of accidents and illness, society will reap the
rewards as studies that originated in Buffalo reach fruition and are developed into
clinical practice throughout the country, and the world.

At UB and The Children's Hospital of Buffalo , along with
four other centers nationwide, l3 premature babies who
teetered on the brink of death from respiratory failure
earlier this year were treated in the first clinical trial using
partial liquid ventilation led by Corinne L. Leach, M.D. ,
Ph .D., assistant professor of pediatrics and attending neonatologist at Children's. This revolutionary technique was
first described by Bradley P. Fuhrman, M.D.,
chief of pediatric critip LA T
"THE
I
cal care at the hospital
and a professor of pediatrics at UB. All of the
infants responded with
I S
FUTURE
TO
improvement in their
lung function, and
seven ultimately survived . Known also as
A
CHILDREN
perfluorocarbon-associated gas exchange, or
PAGE, partial liquid
ventilation could significantly enhance treatment for not
only newborns, but older children and adults who suffer
from lung disease.
"Treatment is a way of taking advantage ofliquid to make
a collapsed lung available for use ," explains Fuhrman. "It
will be especially effective in situations where there is
generalized lung collapse, such as acute respiratory distress
syndrome and hyaline membrane disease . It showed very
good effectiveness in the trial involving the l3 babies, all of

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whom were expected to die and had failed with all conventional forms of treatment, including surfactant. "
PAGE also has been used to treat children with viral
pneumonia and in patients with bacterial infections that
cause lung collapse. "The plan in the near future is to do this
in children and adults," as well as newborn babies, notes
Fuhrman.
"PAGE is a potentially major breakthrough," according to
NEAR
N
THE
Bruce A. Holm, Ph .D.,
dean for research and
graduate studies at UB.
"Its history lies in anD 0
I N
T HI S
other development: the
development of surfactant. "
The results of the
D
ADULTS "
first clinical trials showing the efficacy of surfactant were published
in Buffalo in 1985. A combination of phospholipids and
proteins, surfactant is normally produced in the alveoli and
secreted into the lung, where it is responsible for lowering
surface tension. The initial production of surfactant in the
laboratory, and later by commercial firms, has changed the
standard of care for the treatment of respiratory distress
syndrome.
PAGE carries the basic concept behind surfactant a giant
step forward.

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�R oge r Kais e r , M.D.

in back g round , and Bhup e ndra Mepani , M . D. , view X-r ays from th e first clini ca l tri a ls .

"It takes a patient who is unstable and poorly oxygenated
and offers a more stable course," says Fuhrman. "We think
we'll reduce the risk of having this kind of lung disease. "
Leach, who collaborates with Fuhrman, and developed
this technique in the treatment of respiratory distress
syndrome, reported the results of the pioneer clinical trial
at the May 10, 1995 meeting of the Society for Pediatric
Research in California. Leach came to UB in 1988 from the
University of Pennsylvania and the Children's Hospital of
Philadelphia , having worked with Thomas Shaffer, Ph.D. ,
of Temple University, who designed an early liquid ventilator, and is considered the modern-day father of total
liquid ventilation. In addition to Fuhrman and Leach , Erie
County Medical Center's Roger Kaiser, M.D., clinical associate professor of anesthesiology and clinical assistant professor of surgery, has been instrumentally involved in
studies using PAGE on adults .
"Brad Fuhrman simplified the entire process of partial
liquid ventilation and launched it into the clinical arena ,"
according to Leach. "While he was in Pittsburgh, he figured
out that partial liquid ventilation could work; at the same
time I was doing total liquid ventilation research here at UB.
We got together, and I modified it to work in the sick
premature lung. Since then , our team at UB , including Drs.
Michelle Papo, David Steinhorn, Lynn Herman and Roger
Kaiser, has developed PLV in the treatment of many dis-

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eases, which has led to subsequent pediatric and adult
clinical trials of PAGE. "
And, as the landmark study of the l3 infants proves, it
does work. Reaching this milestone took approximately 30
years, during which time one of the major barriers to clinical
application was the fact that liquid breathing required a highly
specialized ventilator. Fuhrman successfully leapt this hurdle.
"PAGE requires the standard ventilator already used in hospitals ," he explains. "It doesn't require a shift in the way we do
ventilation. It just makes existing methods work better.
"We think it will make the lung more uniform and therefore
more available for ventilation," he continues. "The spin-off
could be quite large. There are 150,000 ARDS (Adult Respiratory Distress Syndrome) cases in the United States. In addition,
many patients develop lung disease as a component of other
problems. PAGE actually contributes to the treatment of many
different diseases."
Describing his role in the development of PAGE, Kaiser
notes , "my role has been supportive of Fuhrman. Most of my
work has been in sheep, utilizing an acid aspiration lung
injury model. "
Kaiser used sheep in his laboratory trials because initial
work had been done on smaller animals. As a prelude to
human adult trials , large animal trials were conducted. Much
research has been funded by the Alliance Pharmaceutical
Corporation, San Diego , which holds the patent on medicalgrade perflubron, the fluorocarbon commonly used in PAGE.
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�"Brad Fuhrman first discussed PAGE in the
july 1991 issue of Critical Care Medicine. Alliance contacted him immediately and matched
Fuhrman with our chemical, perflubron," according to Hal W. DeLong, executive vice
president of business development/marketing
at Alliance.
"One of the pleasant surprises has been that
humans responded so similarly to animal models, which indicated the efficacy of the technique in treatment," adds DeLong.
Kaiser notes that three human trials for
PAGE- in neonates, pediatric patients and
adults- have been initiated since 1993. "We
are starting Phase II of trials in adults this
summer," Kaiser says. "This will be a controlled
study of two separate groups, one treated with
PAGE and a control group treated with standard
therapy. We will look at a number of different
parameters to see how effective this therapy
really is, whether it lowers the number of days
spent on a ventilator, and whether it affects
outcomes regarding mortality. Then, Phase Ill
trials, which will be more broad, will be done. "
Sites for this summer's adult trials include
ECMC and BGH. Kaiser predicts that ifinvestigators' data work and the PAGE technique are
shown to be of value, actual clinical application in
adult patients could be implemented within the
next two years.
Perfluorocarbon is much less expensive to
manufacture than its predecessor, surfactant.
Other potential benefits to the patient include
a shorter hospital stay and lower morbidity.
And in years to come, the ultimate achieveBR AD L EY P.
F u H R M AN,
M.D.
ment of PAGE researchers could be to prevent
ARDS entirely.
"Once we demonstrate that this is
working the kinks
effective therapy for
out on that," says
" I T TAKeS A PATIENT WHO IS UNSTABLE
ARDS, the next step
Leach. "Partial liqwould be to look
uid ventilation will
into its use prophybe one of the theralactically," predicts
pies available in the
AND POORLY OXYGENATED AND OFFERS
Kaiser. "Preliminary
'90s and in the fudata show that
ture for the treatperfluorocarbon
ment of lung dismay also minimize
ease. We have a lot
A MORE STABLE COURSE. "
inflammatory reof data to show that
sponse; therefore,
other state-of-thewe could actually
art therapies such as
minimize lung damsurfactant have been shown to combine well with PAGE. This
age before it happens. "
gives us every reason to suspect we will use them in combinaCombining surfactant and partial liquid ventilation to comtion in the years to come," she concludes.
+
bat lung damage is also being investigated, although "we're still

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�FuNDING

CUTS

RESEARCH

IMPERIL

look at research sites or the opportunity for investigators
to visit Washington , D.C. , to present their cases.
Furthermore, the effect of federal budget cuts is
discouraging for researchers - new and experienced
alike- whose applications are turned down by agencies
such as NIH.
"Because we have a larger number of investigators and
a smaller number of grants being funded, more investigators tend to reapply. The work load on their part is
tripled. This is demoralizing for young scientists. It has
discouraged people from academic research," says Holm.
"And , we're seeing senior investigators with 25 or more
years' experience being turned down. The statistics are
not flattering for anyone."
UB , however, seems to be an exception to this national
trend . During the past three years the university has seen
a 20 percent growth in extramural grant funding into the
School of Medicine and Biomedical Sciences.
"We've managed to buck the system," concludes
+
Holm, "but how long can we keep it going? "

Thrilling new developments in medical research have
moved major centers like UB into the international
limelight as the wombs , birthplaces and cradles of cure
and prevention for such life-threatening conditions as
lung disease . But how will federal funding cuts threaten
to nip these pioneer efforts in the bud? The outlook is
ominous, according to Bruce A. Holm, Ph.D. , UB dean
for research and graduate studies.
"The rate of growth for funding is not matching the
rate of growth of the body of knowledge or the number
of researchers ," notes Holm.
The future work of the ational Institutes of Health,
foremost agency among research funding in the United
States, is severely jeopardized.
"There have been dramatic cuts in-house at the IH.
It's a matter of time before this impacts on productivity,"
says Holm. For instance, the NIH has completely eliminated research-related site visits as a means of cutting
expenses. Review of applications for funding is now
based solely on the written word, without a first-hand

RESEARCH THAT CHANGES LIVES: A CHILDREN's HERITAGE
with PKU in 19 58- one year before Guthrie discovered the test that screened
Thirty-six years ago, Children's Hospital was the site of another life-saving
for the disease and 10 years before newborn screening became standard
research breakthrough when Robert Guthrie, M.D., who died this year on
hospital practice.
June 24 alter a long illness, changed the nature of newborn screening for mental
PKU babies are born with normal intelligence, but become retarded if they
retardation with his heel-prick blood test lor the presence of phenylketonuria
follow a normal diet. Early detection and treatment with a specialized formula
(PKU).
are essential- and must become a lifelong habit. Today, efforts are focused
Infants born with the disorder are unable to metabolize the essential amino
on caring for older children and adults, as well as
acid phenylaline, which builds to toxic levels and
newborns, affected by PKU. "It's important to treat
leads to mental retardation. If detected at birth,
infants as early as possible to lower the level of
children can lead normal lives if they follow a
phenylketonuria. Within 10days to two weeks alter
special diet that excludes foods containing large
a child is born, the diet begins," notes Georgirene
amounts of protein.
Vladutiu, Ph.D., associate professor of pediatrics
Guthrie's PKU test is now standard for newand neurology at UB and director of the Guthrie
borns in all 50 states and 25 countries, and is
laboratory.
estimated to have spared 30,000 people worldwide
At the laboratory, all PKU patients in
from mental retardation. In Buffalo, his legacy
Western New York- atleast1 00 at any given time
continues through the efforts of the Robert Guthrie
- ore monitored, and a nutritionist studies and
Biochemical Genetics laboratory, located at
modifies their diets as needed. Monitoring for paChildren's Hospital, the site of his original work.
5 Hospital in 1982 •
Dr.
Robert
Guthrie
at
Children'
tienls
in North Dakota and parts of Ohio is also done
Guthrie credited his son, John, and his niece,
there.
Margaret Doll, with being the inspiration for his
research and campaign to get newborn testing widely accepted. John Guthrie,
"Whenever a patient is pregnant, we monitor her PKU level weekly during
who had non-PKU mental retardation, died earlier this year at age 47. Margaret
the entire pregnancy. We also test the baby, of course. Most of the time, if the
Doll is profoundly retarded and lives in a Minneapolis group home. She was born
mother has followed her diet, the baby is line," Vladutiu says.+

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... . ........................................... .. .......... ... .. . .......................

~
I

Naughton to step down as dean after 20 years
WILL PURSUE TEACHING AND RESEARCH AT THE MEDICAL SCHOOL

ohn P. augh ton, M.D., vice presi- the academic side, clinical practice and among the hospitals loosely affiliated
dent for clinical affairs and dean of research . All three activities have devel- with the medical school; residency prothe school of medicine and bio- oped in a very significant way, testi- grams were administered and run by
medical sciences for the last 20 mony to the fact that the medical school them , with little cohesion and consishas risen to become one of the top tency from hospital to hospital.
years , will resign july 1, 1996.
The community's health care sufaughton made the announce- medical schools in the country. "
Naughton said he plans to stay at UB, fered for it, with competition between
ment to a stunned group of colleagues and
well-wishers gathered March 1 in the teaching undergraduate· and graduate the over-bedded hospitals resulting in
atrium of Cary-Farber-Sherman to cel- medical students, pursuing his research splintered services, rising health care
ebrate his 20th anniversary at the medical specialty- cardiac disease exercise re- costs and fiscal woes for all of them.
aughton, in his role as vice president
school. His retirement date coincides with habilitation - and working with the
the school's sesquicentennial celebration. school's faculty on the evolution of an for clinical affairs, is widely credited with
Naughton said he came to his decision interdisciplinary curriculum. Another helping to tum the situation around by
to step down, "by realizing that 20 years is project, he adds, will be capturing his bringing the hospitals together in a coopa long time to be dean. The
erative rather than comthings I'd planned to accompetitive arrangement that
"For 20 years, he's demonstrated a unique and uncanny ability to get parties to the
plish have been accomsaw them enter into a
plished. It's time for the uniconsortia! agreement in
table and work at consensus-building strategies among parties that otherwise would 1983 to respond to guideversity to evaluate the leadership of the school. " He
lines promulgated by the
credited the university for
Liaison Committee on
not. His ability to do this in this environment is going to be greatly missed."
Graduate Medical Eduits continued "support for
cation.
the clinical changes made at
- John E. Friedlander, president and CEO of The Buffalo General Hospital
The Graduate Medithe medical school and its
primary care initiatives."
cal Dental Education
William Greiner, president of UB, "unique experience in Buffalo of col- Consortium of Buffalo has served as a
said, "john has led his school into the laboration and health care change."
model for the nation and achieved sigAnd in his 20 years as dean of the nificant accomplishments , among them
ranks of the nation's top 10 comprehensive medical schools. He has also re- medical school-12 of them also as vice the designation of The Buffalo General
shaped the medical school's connec- president for clinical affairs for the univer- Hospital as the regional heart-lung transtions with the Western New York medi- sity- Naughton has seen a lot of change. plant center; the establishment of a single
A nationally prominent cardiologist, division of neonatology in pediatrics to
cal community at large. He helped to
create extraordinary new relationships he came to UB as dean and professor of coordinate neonatal care, research and
with UB's affiliated teaching hospitals, medicine from George Washington education; the establishment of a PET
relying on a consortia! model that has University School of Medicine and center at the Buffalo VA Medical Center
garnered national attention as a new ap- Health Sciences, where he served as and Millard Fillmore Hospital; and the
proach to medical education."
dean for academic affairs , in 1975. At designation of the regional Trauma-Bum
john E. Friedlander, president and that time , UB's medical school was beset Center at Erie County Medical Center.
CEO of The Buffalo General Hospital, by a lack of direction and leadership ,
The consortium also governs all resisaid, "He's dedicated himself to con- with both morale and research funding dency programs in Western ew York,
tinuing in an outstanding way the medi- support low after the 1962 merger be- serving as the "institution of record" for
cal mission here. Dr. aughton has a tween the once private University of graduate medical education, and is regreat deal of understanding of the three Buffalo and the public State University sponsible for standardizing residents'
important aspects of medical school- ofN ew York. Clinical teaching was split salaries and managing their credentialing.

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medical staff president] ames P.
alan, M.D., BGH president
William V. Kinnard, M.D., and
the immediate past president of
the hospital's board of trustees,
Robert S. Scheu, all of whom
helped draft the plan with
Naughton. Scheu and alan
served as associate directors of
the project; Kinnard chaired a
task force that investigated the
business and legal aspects of the
proposed merger.
The plan was eventually
killed in the county legislature
when that body failed to establish the nonprofit management
corporation that would run the
consolidated hospitals by one
vote- l3 in favor, 7 against.
Perhaps, ironically, many of
the recommendations made in
the report have been borne out
by time - from the closing of
the nursing schools, to the conJohn P. Naughton, M.D., vice president for clinical affairs and dean of the School of Medicine and Biomedical Sciences.
version of the former Deaconess
aughton was appointed vice presi- recommended that Children's be phased Hospital to a skilled nursing facility and
dent of clinical affairs in 1984 after serving into a new nonprofit corporation that the area's decreased inpatient bed capacity.
in that capacity as acting vice president of would manage it along with BGH, Deaa ugh ton accomplished much in his
health sciences for a year. The position coness and Meyer in the county facility 20-year tenure, for both the medical
gave him greater authority over clinical that was under construction at the time. school and its teaching hospitals. His
teaching areas- at UB, without its own The merger plan proposed that acute watch saw the school garner significant
medical center, the affiliated teaching care would be provided by the new research funding and prestigious grants,
hospitals sites- and graduate as well as county hospital and BGH, with the em- among them the Robert Woodjohnson
undergraduate medical education.
phasis at BGH shifted from inpatient to Generalist Physician Initiative, the
But aughton's tenure was not with- outpatient services. It also recommended Women's Health Initiative and the
out controversy. Two years after com- that Deaconess Hospital be converted Markey Trust award. He was instruing to Buffalo, he was asked by officials into a nursing care facility, that the mental in making the School of Mediof The Buffalo General Hospital, The nursing schools at BGH and the county cine and Biomedical Sciences a leader in
Children's Hospital of Buffalo and the be closed and that Columbus and the the push for primary care, and is also
former E. ] . Meyer Memorial and Dea- now defunct lafayette General Hospital credited with unifying the-school's camconess hospitals to head a study into the move into the Children's facility.
pus with the construction of the new
Bolstered by support from a "Citizen's medical research building and the Caryfeasibility of merging those hospitals.
The resulting report- portions of which Committee to Save Children's Hospital" Farber-Sherman complex, as well as inleaked to newspapers months before its that garnered over 200,000 signatures on stituting a consolidated computer netofficial release - set off a storm of a petition to keep the facility open and work among the hospitals and medical
protest within both the medical com- independent, the hospital's medical staff school, now operated by the Health Sciand board of directors voted against the ences library and known as HUB ET.
munity and the community at large.
The report - citing the area's l3 consolidation, as did the medical staff at
percent underutilized bed capacity Buffalo General in a sharp rebuke to Con~nued on page 20

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[1]
~

I

Richard Krugman M.D~ delivers
1995 Stockton Kimball Lecture

Naughton, Continued from page 19

Naughton also instituted UB's medical scientist training program for M.D.Ph.D. students and its successful early
assurance program. His tenure saw steep
increases in the quality of the university's
medical students and an added focus on CHARGES MEDICAL PROFESSION TO MAKE CHILD
minority medical education. He also ABUSE A PUBLIC HEALTH PROBLEM FOR PHYSICIANS
spearheaded increased parental involvement in undergraduate medical education at UB with the formation of a parichard Krugman , M.D. , is a man nation's top childhood diseases. Child
ents council and other programs.
with a mission: to reinvent the abuse affects more than 2.5 percent of
Naughton says, "the job for my suctreatment delivery system for vic- children nationwide each year. As a
cessor will be to help provide creative
tims of child abuse in our society. University of Colorado Medical School
leadership in an ever difficult, con"We must change the focus of intern more than 30 years ago, Krugman
strained environment" anticipated by
child abuse from a social services worked with Dr. Henry Kemp , who conboth federal and state budget cuts. and law enforcement
"There's an awful lot of uncertainty ," he mode to a public health
remarks , "and we haven't seen all the approach concerned with
fallout yet.
preventive treatment ,"
"We've been done dirty in a way. We said Krugman, who shared
were moving on pathways that looked his mission with a crowd
more at regulation and coordination. of hundreds of UB mediAnd now we're caught in a social whirl cal school alumni on Sat- or maybe whirlpool - where we're urday, April 29 .
uncertain of the changes fostered by
Krugman delivered the
competition and withdrawal of support. " keynote address at the
Add to that, he says, the "reductions Medical Alumni Associafrom the hospitals in practice income tion 's Spring Clinical
and research, and medical schools Day, held at the Marriott
throughout the country will have to try Inn in Amherst. Although
to re-sort things. We hope to maintain he is now dean of the Unithe emphasis on what we're all abou t - versity of Colorado Mediquality patient care, education and re- cal School in Denver ,
search. "
Krugman still spends 10
At a Medical School Executive Com- to 20 percent of his time
mittee meeting he attended last spring, speaking on and researchGreiner stated he intends to pursue the ing child abuse and neselection of a new dean and to separate glect, his passion since he
that position from the post of vice presi- was a medical student. He
dent of health sciences. A search com- is a former practicing pemittee will be formed soon to search the diatrician and worked
vice president position.
briefly as an advisor on
In discussing his tenure, Naughton health care issues to
Richard Krugman, M.D.
said, "I think my biggest accomplishment former U.S. Senator David
has to be bringing the hospitals and medi- Durenberger of Minnesota.
ducted a pioneering study on battered
cal school together to see that they could
Krugman explained that child abuse children. "In 1960, we thought we had
work for mutually cooperative goals." + is more prevalent than congenital heart uncovered the scope of the problem
B Y
NANETTE
TRAM ONT
defects or asthma, making it one of the when we found evidence of a few hun-

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dred cases in Colorado," Krugman recalled, "and we thought it would be
relatively easy to take care of." Today,
more than three million reports of child
abuse are filed each year. And 15 percent of all men, and 27 percent of all
women now report some form of sexual
abuse during their childhood, Krugman
explained.
Child abuse is finally recognized as a
problem, said Krugman, but its root
causes are not being adequately addressed. "As a society, we have attention
deficit disorder," said Krugman. "We
are quick to recognize a problem but
long to cure it. We simply move on to
another problem." Increased childhood
and family stress, brought on by a lack
of quality time as a nuclear family and
events like divorce and out-of-wedlock
births (both up 400% since the 1960s,
Krugman points out), contribute to the
high incidence of child abuse in our
society, according to Krugman. "Kids face
increasing isolation and stress," he said.
"What we have is an emergency. We
spend billions of dollars on the downstream effects of not treating child abuse
early," he said, "but it is really quite
extraordinary that, as a society, we are
still in a basic stage of denial regarding
this issue. "
The impact of childhood abuse is
lifelong, linked to an unusually high
suicide rate among pre-pubertal children and contributing to such teenage
and adult complications as eating disorders, developmental disabilities, even
chronic headaches and moderate to severe chronic physical shaking, according to Krugman.
To solve the dilemma, Krugman advocates a system of home health visits to
sufferers of child abuse by trained medical professionals. Currently, abuse victims are dealt with by social service
professionals , who, according to
Krugman, are woefully overworked and
undertrained to deal with the problem.
"Many parts of the country require only

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means a system that makes it easy for a
potential abuser to pick up the phone,
reach a trained professional and say 'I
need help ,"' said Krugman.
Physician advocacy and market forces
will create the environment needed for
real reform in child abuse treatment, believes Krugman. The downstream costs of
these medical issues will force the health
care delivery market to begin making the
types of adjustments it needs in order to
provide preventive care to children
and potential abusers, Krugman predicts.
"Health care reform," he added, "is happening already. It is a market-driven force
moving, like the weather, from west to
east across the country."
Krugman is not the first in his family
to make a medical name for himself. His
father, now retired in Florida, conducted
extensive research which led to the first
vaccine for hepatitis B.
Seated next to UB's long-tenured
medical school dean, john Naughton,
M.D. , Krugman observed that being dean
of his medical school is "not a unique
opportunity. l am the ninth dean in
twelve years." Looking over the list of
past Stockton Kimball speakers,
Krugman even noted that he was not
even the first dean from the University
of Colorado to be featured. Krugman
also joked that, being from Denver, he
shared Buffalo's pain each football season. Despite four appearances each,
neither the Bills nor the Denver Broncos
have ever won a Super Bowl.
The luncheon's namesake, Stockton
Kimball, served as dean of the University
of Buffalo's School of Medicine from 1946
until his untimely death in 1958 at the age
of 55. Kimball's tenure saw the medical
school moved from its old home at Main
and High Streets downtown to its current
location at Main and Bailey, on the southeast corner of the South Campus. The
move poised the medical school, which
was still private, for its later merger with
+
the University ofBuffalo and SUNY.

a high school diploma to become a case
worker," said Krugman, "and their lack
of knowledge is striking."
Krugman believes money to finance
the shift in emphasis in treating child
abuse can be "squeezed out of the already shrinking health care delivery system. " He made an example of two friends
of his from Denver, both doctors who
owned their own HMOs and decided to
merge. "Then another, larger HMO came
in and bought them out. othing
changed as far as service delivery was
concerned, but my two friends split more
than $6 million.
"If the health care delivery field has
enough money out there to make my
two friends millionaires, there is money
out there to fund child abuse treatment," chastised Krugman. He added
that his home health visitation system
would also reduce the number of inappropriate visits to emergency rooms,
the most costly way to deliver public
health services.
Krugman praised the recent opening
of a multidisciplinary Child Advocacy
Center on Delaware Avenue in Buffalo.
Though becoming more common in the
west, it is the first center of its type in
New York State, with the second due to
open soon in Niagara County. The Child
Advocacy Center is a cooperative effort
of representatives from various area social service agencies designed to offer a
single outlet for investigation, support,
advocacy and medical treatment for
sexually abused children and their families. The atmosphere is designed to minimize the amount of trauma involved to
the children and perpetrators of abuse
in seeking treatment.
"Abusive parents love their children
very much,just not very well," explained
Krugman. Abuse is compounded because today's perpetrators were often
abused as children, he added. Early intervention by trained professionals is
the best treatment, he explained. "That's
why I say that preventive treatment

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�Sisters of Charity Hospital history reflects its mission
BUFFALO'S FIRST HOSPITAL BUlLT ON SERVICE TO THE LEAST FORTUNATE

he roots of Buffalo's first hospital Humboldt streets. The 30-acre site was to its present location, absorbing St.
can be traced to the mid-19th cen- purchased from Austin Flint, M.D., the Louise de Marillac Maternity Hospital
tury when the diocese's Bishop, first medical staff chief at Sisters Hospital. into its maternity unit and thus consolijohn Timon, traveled to Baltimore
Land was also purchased at Main and dating all the Sisters of Charity health
to request the services of the Sis- Delavan streets to help meet the grow- care services.
ters of Charity to establish a hospi- ing medical needs of the city. A new
Over the years, Sisters Hospital has
tal for the Queen City of the Lakes, a hospital, accommodating 300 patients, undergone extensive additions, renovagrowing frontier on its way to becoming was completed in 1876. From 1877 to tion and modernization. The first addia major transportation center.
1882, some 4,420 patients were treated tion, built in 1948, housed the emergency
Bishop Timon had purchased a brick there at a total expense of$19,000. About department, family health center, patient
school house and adjoining cottage on half the patients were charity cases.
rooms and outpatient treatment centers.
Pearl Place in the city. The property,
By 1884, four distinct Daughters of
A five-story building added in 1965
which he turned over to the
changed the face of the hossix sisters who traveled to
pital, encompassing its adBuffalo to start the hospital,
ministrative offices and rnabecame the first site of the
ternity service, as well as
Sisters of Charity Hospital in
patient rooms, conference
1848. The Sisters of Charity
areas, the medical records
in America became known
department and physician
two years later as the Daughlounge. Another addition
ters of Charity of St. Vincent
constructed two years later
\"JEW OF TUE llEDlC..!.L COLLEGE, ASD TUE llll:~~~~ll~S~_;-~~F::,T~~-~.o:=u:.:~._._
housed the pharmacy, cende Paul, officially joining with
the order established in France in 1633. Charity hospitals filled specific needs in tral supply, diagnostic imaging and purWithin a year of its opening, Sisters the community - the newly opened chasing departments.
Hospital was faced with its first test with Emergency Hospital at Pine and Eagle
Inl974,theSetonProfessionalBuildthe outbreak of four cholera epidemics streets, Sisters Hospital for the sick at ing and St. Catherine Laboure Health
in Western New York. Patients jammed Main and Delavan, St. Mary's Infant Center additions were completed- the
the hospital; many recovered, but the Asylum and Maternity Hospital for or- Seton Building housing medical and
epidemic would claim 900 lives before it phans and unwed mothers at Elmwood commercial offices along with hospital
subsided.
and Edward and Providence Retreat for extension offices, and the St. Catherine
ln 1854, the Daughters of Charity the mentally ill at Main and Humboldt. facility housing a concentration of rehaexpanded their services to the City of
Established originally as a downtown bilitative services including physical and
Buffalo with the establishment of St. branch of Sisters Hospital, Emergency occupational therapy, social work and a
Mary's Infant Asylum and Maternity Hospital was taken over by the Diocese skilled nursing facility.
Hospital. The facility, which remained of Buffalo in 1954. lt is now known as
Re-Vision 2000, Sisters Hospital's
open for nearly a century at Elmwood Sheehan Memorial Hospital.
major modernization project completed
and Edward streets, cared for orphans
Providence Retreat was closed in last year, added two more stories to the
and unwed mothers.
1940. Two years later, Sisters Hospital main structure as well as new surgery,
In 1860, Bishop Timon felt the dio- opened the St. Louise de Marillac Mater- coronary and intensive care units. The
cese needed an institution dedicated to nity Hospital, which merged with St. project also included the construction
the care of the mentally ill. The Daugh- Mary's Hospital in the Providence Re- of a new building named after Sr. Mary
ters of Charity opened Providence Re- treat building.
Charles Dever, former hospital presitreat the following year on the site of the
Sisters Hospital remained at Main dent, to house the information systems
present Sisters Hospital at Main and and Delavan untill948 when it moved and finance departments.

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baton were designed
served as director of the
and constructed by Dr.
Visiting Nurses AssociaBrown, as well as the
tion from 1975 to 1978
case in which they are
and was a member of the
medical honor society,
displayed, and he also
Alpha Omega Alpha, the
designed the school's
Medical Foundation of
academic gown, a
Buffalo , the Faculty
chandelier and doors
Club, the Medical Hisin the complex to
torical Society, the
which he devoted his
Albright-Knox Art Gallife.
lery, the Museum of SciIn recognition of his
ence, the Buffalo and Erie
strong support of the
County Historical Society
Health Sciences Li- Robert L. Brown, M.D. , 44
and
the Friends of the
brary for 26 years, the
historical and rare book collection was School of Architecture. He was also a long
named the Robert L Brown History of standing member of the Buffalo Club.
He is survived by his sister-in-law,
Medicine Collection in 1985. Upon his
retirement that same year, he was ap- Mrs. Donald (Virginia) Brown; a niece,
pointed consultant to the University Li- LauraMehl;a nephew, Kenneth P. Brown;
braries and continued his close associa- and his good friend , Donald]. Savage.
tion with the History of Medicine Collec- Contributions may be made to the University at Buffalo Foundation, P.O. Box
tion until his death.
Dr. Brown received the Dean's Award 590, Buffalo, New York 14231-0590 for
+
in 1967 and 1973, and the Distinguished the History of Medicine Fund.
Medical Alumni Award in 1974. He - B y L I L L I S E N T Z

In addition to the facilities located on
the hospital campus, Sisters has continually expanded its off-campus sites. In 1981,
it opened the Alden Medical Center; in
1989, it opened an outpatient chemical
dependency STAR unit in Amherst followed by a second a year later in West
Seneca.
In 1992, the hospital opened the St.
Vincent Health Center on Buffalo's East
Side and the St. Louise Health Center on
the city's West Side.
Sisters moved into the north suburbs
with the opening two years ago of its
Amherst Health Center.
From its humble beginnings nearly
150 years ago, the history of Sisters Hospital is reflected in its services to Buffalo's
poor, mentally ill and orphaned. The hospital has grown tremendously from its
one-building roots to a network of health
care facilities encompassing a full range of
acute and long-term care as well as inpatient and outpatient services.
+

Robert L. Brown, M.D, former
associate and acting dean,dies

GRADUATION DAY 1995
It was a day for celebration and

obert L. Brown, M.D. '44, former
associate dean and acting dean of
the University of Buffalo's School
of Medicine, died April 5, 1995
after a brief illness.
Dr. Brown's accomplishments
and contributions to the medical school
weremanyand varied. He was appointed
assistant dean in 1959 and acting dean
in 1960, when he directed the intensive
planning for the university's merger into
the State University of ew York system
two years later. He was the first associate
dean appointed to the School ofMedicine.
In 1974, Brown became the medical
school's archivist, beginning a systematic search for the historical records of
the school that led to the categorization
and preservation of many original
records from the early years of the school.
The medical school's mace and marshal's
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festivities as the School of
Medicine and Biomedical Sciences
graduated its 149th class of
physicians and medical scientists
this past May.

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Match Day 1995: Success and Celebration
UB'S GRADUATE MEDICAL DENTAL EDUCATION
CONSORTIUM RESIDENCIES DRAW 35 PERCENT
OF ITS GRADUATING MEDICAL STUDENTS THIS YEAR

his year's doss of graduating medical students did well on the National
Resident Matching Program, with 67 percent getting their first choice and
83 percent getting one of their first three choices.
Of the 140 UB students participating in the NRMP, 35 percent will
remain in Buffalo in Graduate Medical Dental Education Consortium
residencies; 11 percent will stay in New York State, but outside Buffalo; and
51 percent will do their residencies out of state. Seven students were unmatched.
Primary care residencies drew 40 percent of UB's graduating physicians, down
from last year's 44.1 percent.
Nationally, the program matched 17,858 of the nearly 23,000 students who
competed for the 20,751 first-year residency positions available. More than half
were matched in generalist residencies, including family practice (15.4 percent),
internal medicine (24.5 percent) and pediatrics (11.1 percent).
Omolora J. Akinbomi, Pediatncs, Children's
Nauonal Medical Center, Washington,
DC

George J. Burnett, Psychiatry, Graduate
Medtcal Dental Education Consortium,
Buffalo, NY

Mory J. Ciotoli, Emergency MediCine,
Umverstty of Rochester/Strong
Memorial Hospllal, Rochester, Y

Trine B. Allen, Psychiatry, Duke Umverstty
Medical Center, Durham, NC

Timothy R. Byrnes, Internal MediCine
(Prehm.), Ststers of Chanty Hospllal,
Buffalo, NY

Lori A. Cohen, Internal Medicine, Long
Island jewish Medtcal Center, ew
Hyde Park, NY

Darren M. Coparoso, Family Pracuce,
Graduate Medtcal Dental Educauon
Consoruum, Buffalo, Y

Richard J. DeAsla, Surgery, University of
Rochester/Strong Memorial Hospllal,
Rochester, NY

Michael J. Carlson, Internal Medicine,
Medtcal College of Virginia, Rtchmond,
VA

Tracie l. DiMarco, Family Practice, New
York Medical College Mtd-Hudson
Family Pracuce Serv1ces lnsmute,
Kingston, NY

lhuoma U. Alozie, Internal Medtcine
(Prelim.), Hospllal of St. Raphael, New
Haven, CT
Andrew l. Altman, Urology, Case Western
Reserve Umversity, Cleveland, OH
Barry R. Armondi, Internal Medicine
(Pnmary Care), Long Island jewish
Medical Center, New Hyde Park, NY
Brett D. Arnoldo, Surgery, Graduate Medical
Dental Education Consorl!um, Buffalo,
NY
Robert A. Borroli, Emergency Medicine,
Maricopa Medtcal Center, Phoemx, AZ

Katherine A. Blum, Obstetncs and
Gynecology, Graduate Medtcal Dental
Educal!on Consortium, Buffalo, NY
Miroslav P. Bobek, eurologtcal Surgery,
Universlly of Mtchtgan Hospllals at Ann
Arbor, Ann Arbor, Ml
Maurits S. Boon, Surgery (Prelim.). Thomas
jefferson UmverSily, Philadelphia, PA
Otolaryngology, Thomas jefferson
Umverslly, Philadelphia, PA

Anthony J. Bartkowiak, Internal Medicine
(Pnmary Care), Graduate Medical
Dental Educauon Consortium, Buffalo,
NY

Maria D. Bruno, Internal Medicine (Prelim.),
Graduate Medtcal Dental Educauon
Consortium, Buffalo, NY
Ophthalmology, Graduate Medical Dental
Educauon Consortium, Buffalo, NY

Ross J. Bellavia, RadiOlogy- Dtagnosuc,
Umverslly Hospllals of Cleveland,
Cleveland, OH

Cheryl D. Buck, Medicine!Pedtatncs,
Umverslly of Cincinnal! Hospital,
Cincinnau, OH

Scott J. Belote, Emergency Medicine,
Graduate Medical Dental Educauon
Consoruum, Buffalo, NY

Tony T. Bui, Transitional Year, Wilson
Memonal RegiOnal Medtcal Center
(Unlled Health Services), johnson Clly,
NY
Physical Medicine and Rehabilllal!on,
Universlly of Texas Southwestern
Medical School, Dallas, TX

Kathleen E. Bethin, Pediatrics. St. Loms
Children's Hospllal, St. Louts, MO

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Frank P. Carnevale, Pediatrics, Graduate
Medical Dental Educauon Consoruum,
Buffalo, NY

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liang R. Chang, Obstetrics and Gynecology,
Graduate Medical Dental Educauon
Consorl!um, Buffalo, NY
Craig E. Cheiltez, Internal Medicine,
Georgetown UmverSily Hospllal,
Washington, DC

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C. Dipirro, Pathology, Graduate
Medtcal Dental Educauon Consoruum,
Buffalo, NY

Anthony M. Dirubbo, Medicine!Pediatncs,
Umverstty of Rochester/Strong
Memonal Hospllal, Rochester, NY
Therese M. Duane, Surgery (Prehm.),
Eastern Virginia Graduate School of
Medicine, Norfolk, VA

Karen A. Chojnacki, Surgery, Thomas
jefferson Umverstty, Philadelphia, PA

Karen E. Dull, Pediatrics, Umverstty Health
Center of Plllsburgh, Plllsburgh, PA

Christine M. Chruscicki, Psychiatry, Duke
Umversity Medical Center, Durham, NC

Christopher J. East, Internal Medicine
(Prelim.), Ststers of Chanty Hospllal,
Sebastian J. Ciancio, Surgery (Prehm.), Baylor Buffalo, Y
College of Medicine at Houston,
Anesthesiology, Duke Umverslly
Houston, TX
Medical Center, Durham, NC
Urology, Baylor College of Medicine
Affiliated Urology Program, Houston, TX Daryl R. Ehlenlield, Pediatrics, Graduate
Medical Dental Education Consortium,
Buffalo, Y

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lynelle M. Emery, Famtly Pracuce, Famtly
Practice Residency of Southwest
Washtngton Medtcal Center, Vancouver,
WA
Cynthia E. Epstein, Pedtatncs, Medtcal College
of Virgmta, Rtchmond, VA
AndrewS. Feinberg, Transitional Year, Georgia
Bapust Medtcal Center. Atlanta, GA
Ophthalmology, Emol)' Umverslty School
of Medtcme, Atlanta, GA
Carole Y.Fenton, Emergency Medtcme,
Graduate Medtcal Dental Educauon
Consortium, Buffalo, NY

Faith A. Heavens, Pediatrics, North Shore
Umversity Hospital, ew York, NY
Andrew D. Henry, Internal Medicine,
Umverslty of South Flonda College of
Medtcme at Tampa, Tampa, FL
Nigel I. Henry, Obstetncs and Gynecology,
Brooklyn Hospttal Center, Brooklyn, Y
Aravind Herle, Internal Medtcme, The
Umverslty of Chtcago Hospttals,
Chicago, IL

Huiiung Kim, Radiology- Dtagnosuc,
George Washmgton Umverslty,
Washmgton, DC

Donielle S. Noteboert, Emergency Medtcine,
Graduate Medtcal Dental Educauon
Consoruum, Buffalo, NY

Eric H. Kossoll, Pedtatrics, Eastern Virgtma
Graduate School of Medtcine, Norfolk,
VA

David M. Odell, Famtly Pracuce, St. Joseph
Hospttal, Denver, CO

Shone C. Ferguson, Pedtatncs, Graduate
Medtcal Dental Educauon Consoruum,
Buffalo, Y
Shown P. Ferguson, Pedtatncs, Graduate
Medtcal Dental Educauon Consoruum,
Buffalo, NY

Peter Hertz, Surgery (Prehm.), Graduate
Medical Dental Educauon Consoruum,
Buffalo, NY

Dono lim, Obstetrics and Gynecolog}',
Universtty of Rochester/Strong
Memorial Hospttal, Rochester, :-.JY

Tyrone D. Fillyow, Psychiatry, Sheppard
Prall Hospital, Baltimore, MD

Douglas J. Hickox, Surgery (Prehm ),
Graduate Medical Dental Educauon
Consortium, Buffalo. NY

Arlene D. lobo, Internal Medtcme,
Cleveland Clmic Foundauon,
Cleveland, OH

Meghon A. Higman, Pedtatncs, Unl\·erslty
Health Center at Pmsburgh, Ptusburgh,
PA

Martin C. Moloney, Famtly Medtcme,
Graduate Medtcal Dental Educauon
Consoruum, Buffalo, Y

Evon Hirsch, Family Practice, University of
Cahfornia at San Franctsco, Fresno, CA

Michele M. Manko, Pedtatncs,
Graduate Medtcal Dental Educauon
Consoruum, Buffalo, NY

Jeanne C. Fitzsimmons, Emergency Medicme,
Graduate Medical Dental Education
Consortium, Buffalo, NY
Michelle Game, Pedtatncs, Eastern Virgtma
Graduate School of Medtcme, Norfolk,
VA
Kathy M. Golding, Famtly Pracuce, Graduate
Medtcal Dental Educauon Consortium,
Buffalo, Y
Randy J. Goldstein, Pedtatncs, Medtcal
College of Virgmia, Richmond, VA
JeffreyS. Grant, Internal Medicine
(Prehm.), Ststers of Chanty Hospital,
Buffalo, NY
Physical Medtcme and Rehabtlltauon,
SUNY Health Sciences Center, Syracuse,
NY

James C. Ho, Internal Medtcme (Pnmary
Care), Long Island Jewish Medical
Center, New Hyde Park, NY

Toreq S. Horb, Internal :vtedtcine,
Vanderbtlt Umverslty Medical School,
Nashville, TN

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Michele A. Potempa, Famtly Practice,
Graduate Medtcal Dental Educauon
Consoruum, Buffalo, NY
Susan E. Potts, Pedtatncs, Duke Umverslty
Medical Center, Durham, NC
Kirk Puttlitz, Pathology, Emory Umversity
School of Medicine, Atlanta, GA
lrm R. Roio, Psychiatry, Umverslty
Hospitals of Cle,·eland, Cleveland, OH
Peter D. Roy, Surgery, Umverslty of
Alabama Hospital, Montgomery, AL

Susan M. Noselli, Internal Medtcme
(Prehm.), Jewish Hospttal of St. Louts,
St. LOUIS, MO
Neurology, Washtngton Umverslty, St.
Louis, MO

Helen M. Kim, Psychtatry, Massachusetts
General Hospital, Boston, MA

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Natalie Poppito, Pathology, DartmouthHitchcock Medtcal Center, Lebanon,
NH

James G. Nalbone, Psychtatry, Albany
Medtcal Center Hospital, Albany, NY

Marie I. Kessler, Pedtatrics, Graduate
Medtcal Dental Educauon Consortium,
Buffalo, NY

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Jesslyn l. Perry, Internal Medicme,
Graduate Medical Dental Educauon
Consortium, Buffalo, NY

Brenden M. Miner, Surgery (Prehm.),
Umverslty of Vermont, Burhngton. VT

Heather M. Keene, Obstetncs and
Gynecology, Provtdence Hospital,
Southfield, Ml

James S. Killius, Radiology- Dtagnosuc,
Duke Unl\·erstty Medical Center, Durham,
"iC

Nancy Perez, Pedtatncs, Graduate Medtcal
Dental Educauon Consortium, Buffalo,
NY

Gregory A. McDaniel, Medtcine/Pedtatrics,
Western Reserve Care System/
NEOUCOM,Youngstown, OH

Christina M. Keaney, Pathology, Graduate
Medtcal Dental Educauon Consoruum.
Buffalo, NY

Thomas A. Honno, Famtly Pracuce,
Guthrie/Robert Packer. Guthne, PA

Tushar Patel, Ophthalmology, Scheie Eye
Institute, Unl\·erslty of Pennsylvania,
Phtladelphta, PA

Madhulika Mathur, Pedtatncs, Graduate
Medtcal Dental Education Consoruum,
Buffalo, NY

Jeoneo R. Hundley, Emergency Medtcme,
Graduate Medtcal Dental Educauon
Consoruum, Buffalo, NY

Somir Khonior, Obstetncs and Gynecology,
New Hanover Regwnal Medtcal Center,
Wtlmmgton, NC

Margaret E. Partridge, Pedtatncs, Umverslty
of Rochester/Strong Memonal Hospital,
Rochester, NY

Philip l. Monzonero, Medtcme (Prelim.), St.
Elizabeth's Hospital of Boston, Boston,
MA
Anesthesiology, Oregon Health SCience
Umversity, Portland, OR

David P. Hughes, Emergency Medtcme,
Bowman Gray/North Carohna Bapust
Hospital, Wmston-Salem, NC

Kate l. Guernsey, Pediatrics. Umverslty of
Colorado School of Medtcme at Denver,
Denver, CO

Thomas A. Owens, Medtcme/Pedtatncs.
Duke UniverSit}' :vtedtcal Center,
Durham, NC

Patricio A. Krebs, Pathology, Baystate
Medtcal Center, Spnngfield, MA
Bryon R. lotzmon, Internal Medicme
(Prehm,), Wmthrop-Umversity
Hospttal, Mmeola, KY
Neurology, Mt. Sinat School of
Medtcme, New York, NY

Albert B. Fiorello, Emergency Medtcme,
University of Anzona Affthated
Hospitals, Tucson, AZ

Whitney l. Orman, Pedtatncs,Emory
Unl\·ersity School of Medicme, Atlanta,
GA

Dovid P. Kowalski, Famtly Practice,
Graduate Medical Dental Educauon
Consoruum, Buffalo, NY

Mitchell J. Herr, Internal Medtcme (Prehm.),
Graduate Medtcal Dental Educauon
Consoruum, Buffalo, Y
Anestheswlogy. Umverslty of Cahforma
at San Otego Medtcal Center, San Otego,
CA

Steven M. Finkelstein, Internal Medtcme
(Prehm.), New England Medical Center,
Boston, MA
Anesthesiology, Brigham and Women's
Hospital, Boston, MA

I

Neal T. Reich, Internal Medicme (Prehm ),
Graduate Medtcal Dental Educauon
Consoruum, Buffalo, Y
AnesthesiOlogy, Graduate Medtcal
Dental Educauon Consortium, Buffalo,
NY
Koren M. Roll, Pedtatrics, Hahnemann
UmverSit)-, Phtladelphia, PA

Renee F. Neely, Psychtatry, Graduate
Medtcal Dental Education Consoruum,
Buffalo, NY

Germaine N. Rowe, Internal Medtcine
(Prehm ), Graduate Medtcal Dental
Education Consorttum, Buffalo, NY
Physical Medtcme and Rehabthtation,
Presbyterian Hospital, New York, NY

Gory J. Nielan, Pedtalncs, Baystate
Medical Center, Spnngfield, MA

Amitobh P. Soha, Surgery, Flushmg
Hospttal Medtcal Center, Flushmg, NY

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Theresa M. Sarafin, Pediatncs, Dartmouth-Hitchcock
Medical Center, Lebanon, H

Jeffrey Tessier, Internal Medicine, Portsmouth Naval
Hospital, Portsmouth, VA

Eva H. Sotell, Internal Medicine, Umversny Health
Center at Pittsburgh, Pmsburgh, PA

Edouord J. Trobulsi, Surgery (Prehm.), Thomas Jefferson
Umversity, Pmsburgh, PA
Urology, Thomas Jefferson Umversny,
Pittsburgh, PA

Philip Sauvageau, Medicine!Pediatncs, Graduate Medical
Dental Education Consortium, Buffalo, NY

Bertram Portin '53,to serve on
Sisters Hospital board of directors

Rolph P. Tufano, Otolaryngology, Umversny of
Pennsylvama, Philadelphia, PA

Bethonn Sthober, Pathology, Harbor-University of
Cahforma at los Angeles Medical Center. los
Angeles, CA

Paul F. Updike , Internal Medicine, Dartmouth-Hitchcock
Medical Center, Lebanon, NH

Joel A. Shapiro, Orthopedics, McGaw Medical Center of
Northwestern Umversity, Chicago, ll

Felice Vobnitk, AnesthesiOlogy. Umversity of North
Carolina Hospitals, Chapel Hill, NC

Chondresh A. Shelot, Emergency Medicine, Mt. Sinai
Medical Center, Cleveland, OH

Timothy E. VanDuzer, Emergency Medicine, Graduate
Medical Dental Education Consortium,
Buffalo, NY

Fronk Sindoni, Surgery (Prehm ), Graduate Medical
Dental Education Consortium, Buffalo, NY

Eileen Velez, Pathology, Graduate Medical Dental
Education Consortium, Buffalo, NY

Michael J. Singh, Surgery, Graduate Medical Dental
Education Consortium, Buffalo, NY

Andrew W. Worner, Internal Medicine, Graduate Medical
Dental Education Consortium, Buffalo, Y

Erik D. Skoog, Ophthalmology, Medical University of
South Carohna, Charleston, SC

Theresa M. Wegman, Pediatrics, Graduate Medical Dental
Education C..onsorl!um, Buffalo, Y

Romuold Sluyters, Surgery (Prehm.), Graduate Medical
Dental Education Consortium, Buffalo, Y
Orthopedics, Graduate Medical Dental Education
Consortium, Buffalo, Y

Dennis D. Weimer, Psychiatry, Umversity of Anzona
Affiliated Hospitals, Tucson, AZ

Denise K. Sokolofsky, Pediatrics, Graduate Medical Dental
Education Consortium, Buffalo, NY

Wendy l. Weinstein, Psychiatry, Graduate Medical Dental
Education Consoruum, Buffalo, NY

Stephen P. Sorrentino, Internal Medicine (Pnmary Care),
North Shore University Hospnal, New York, NY

Timothy P. Whelan, Internal Medicine, University of
Colorado School of Medicine, Denver, CO

Taro A. Soso, Internal MediCine (Prehm.), Graduate
Medical Dental Education Consortium,
Buffalo, Y
Anesthesiology, Graduate Medical Dental Education
Consortium, Buffalo, NY

Ellen M. Whyte, Psychiatry, Umversity Hospnals of
Cleveland, Cleveland, OH

Attending Physicians

Matthew Withiom-leitth, Obstetrics and Gynecology,
Graduate Medical Dental Education Consortium,
Buffalo, NY

Peter F. Stengel, Internal Medicine, Umversny of
Maryland, Baltimore, MD

ertram A. Portin, M.D. '53, has
been named to the Sisters Hospital board of directors .
Certified by the American Board
of Surgery and the American Board
of Colon and Rectal Surgery, Portin
is chairman of the hospital's division of
colon/rectal surgery and a past president of the Sisters Hospital medical staff.
"We are fortunate to have someone
of Dr. Portin's leadership ability and
insight join our board of directors ," said
John] . Maher, president of Sisters Hospital. "Dr. Portin's presence on the board
is important to further integrate physician expertise into governance and leadership at Sisters Hospital. "
Portin is a member of the American
College of Surgeons, the American Society of Colon and Rectal Surgeons, the
American Medical Association and the
Accreditation Council for Graduate
Medical Education.
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The award far best reunion class atten-

William J. Wnuk, Medicine/Pediatrics, Graduate Medical
Dental Education Consortium, Buffalo, Y

dance this year goes to the 50-year Class

Andrew N. Young, Pathology, Emory Umversity School of
MediCine, Atlanta, GA

of '45, which, under the stewardship of

Thomas W. Stone, Internal Medicine (Prehm.), Graduate
Medical Dental Education Consortium, Buffalo, NY
Ophthalmology, Duke Umversity Medical Center,
Durham, NC

Brion K. Zebrowski, Surgery, Bridgeport Hospital,
Bndgeport, CT

class reunion choir Herbert Joyce, posted

Erik J. Stumpf, Family Practice, Hahfax Medical Center,
Daytona Beach, Fl

Jeffrey l. Zondermon, Transmonal Year, Carney Hospnal,
Boston, MA
Ophthalmology, Tufts New England Eye Center,
Boston, MA

an approximate

Royte R. Syracuse, Internal Medicine (Prehm.),
Umversity of Maryland at Baltimore, Baltimore, MD
Ophthalmology, Graduate Medical Dental Education
Consortium, Buffalo, Y

Jennifer M. Zubler, Pediatrics, Graduate Medical Dental
Educauon Consortium, Buffalo, NY

dance. Congratula-

Keith A. Zu!!olo, Surgery. St. Elizabeth Hospital Medical

tions to all on a job

lisa l. Stephens, Obstetrics/Gynecology, Baystate Medical
Center, Spnngfield, MA

Eva M. Tokots-Dilorenzo, Obstetrics and Gynecology,
Graduate Medical Dental Education Consortium,
Buffalo, NY

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Center/NEOUCOM, Youngstown, OH

78 percent atten-

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well done!

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�1995 reunion portraits: 50 years of medicine recalled
en classes were honored at this year's Reunion Weekend celebration,
and gathered in Buffalo to reminisce, remember old friends and good
times, and renew acquaintances.

CLASS OF 1945

CLASS OF 1950

FROM lEFT TO RIGHT: FIRST ROW: Richard Adler, Edward Forgrave , john

FROM lEFT TO RIGHT: FIRST ROW: William Webster, Alfred Falcone,

Robinson , Herbertjoyce,jacob Steinhart, Gilbert Tybring, Earl

Robert Bergner , Roland Anthone
SECOND ROW: Henry Pech, Sidney Anthone, Karl Manders, james

Cantwell, Theodore jewett

SECOND ROW: Paul Cotter, Eugene Morhous, William Andaloro,

Dunn , Richard Leberer, Leo Manning, Roy Robinson

Raymond Barry, Genevieve Howen, Vincent Capraro, Ivan Kuhl,

THIRD ROW: Adelmo Dunghe, Eugene Zygaj ,

joseph Sheedy, William Loeser, William Mcintosh

Robert Patterson

THIRD ROW: Charles Wiles, john Fairbairn, Edward Valentine,
john Hartman, Victor Lazarus, Hilton jacobson, john Long,
orman Chassin, George

George Ellis, Richard Greenwald,

Thorngate, Vito Laglia , Adolphe Schoepflin, Leslie Osborn,
Robert Schopp, Peter Terzian, joseph Tannenhaus, A. Arthur
Grabau , Wayne Templer

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Reunion Classes Continued on page 28

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••••••••••••••

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••

•

•

•

•••••••••••

•

•••

w~
There·
Med

Eva H
Cen

Phili!
Den

Beth•
Cal
An!

Joel
No

Chm
Me

fra1

CLASS OF 1955
CLASS OF 1965

De

FROM lEFT TO RIGHT: FIRST ROW: Milton Alter, John Peterson, Leonard
Mic

Schaer, joseph LaMancusa

Ed

SECOND ROW: Bertrand Bell, Ray Schiferle, john Foley, john Baker,

Eril

Frank Gazzo, james unn, Michael Gianturco, Robert Dean,
Robert Pittell, john Kent, james Stengel , john LeValley,
Shedrick Moore

Sc

FROM lEFT TO RIGHT: FIRST ROW: Louis Trachtman, Kenneth Kim,
joseph Cardamone, George Strauss
SECOND ROW: Gary jeffery, W. Scott Walls, Elliott Larson, Antonio
Catanzaro, George Moore, Robert Schuder

Ro
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E

St
1'-

CLASS OF 1960
CLASS OF 1970

FROM lEFT TO RIGHT: FIRST ROW: Harris Faigel, Edward Graber, Algirdas
FROM lEFT TO RIGHT: FIRST ROW: Bruce Prenner, Michael Lippman,
jeffrey Rothman, Bruce Sobin, Laurence Lesser
SECOND ROW: Mary Clemens, Marilyn Kassirer, Roger Forden ,
William Balistreri, Allan Winzer, Arthur Goshin, Lynn Eckhert
THIRD ROW: Dennis DuBois, Seth Craig, Donald Copley, Harold
Vandersea, Brenden Thomson, Thomas O'Connor, Sebastian Conti,
Allen Davidoff, Donald Gabel, Steven Weinstein, jan Novak, Alan
Fink, Arthur Seigel, Shafic Twa!, Elliott Brender

Gamziukas, joseph Antkowiak, Sylvia Sussman, Andre Lascari,
William Abramson, Charles Riggio, Eugene Partridge
SECOND ROW: Marshall Lichtman , Donald Hammel, joseph Chazan,
Harry Metcalf, Donald Donius

THIRD ROW: Harold Brody, james Kanski, Daniel Gianturco,
William Stein, Franklin Glockner, Robert Malatesta, Harris
Kenner, Gerard Diesfeld, Daniel Goldberg, Roger Dayer,
Theodore Bistany, Thomas Guttuso

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�CLASS OF 1975

CLASS OF 1985

FROMLEFT TO RIGHT: FIRST ROW: Shirley Galucki , Barbara Brar , Elaine
Schaaf, Erica Heit Remer, Lynda Stidham , Margaret Reidy,
Roberta Moss, Elizabeth Maher, Lucie DiMaggio , Darlene
Eldredge Fairchild, Amy Miller O'Donnell , C. Adrianna Alvarez,
Donald Tingley, Graciela Desemone , Thomas Cowan
SECOND ROW: David Forster, Carol Hammer Forster, Sabino Torre,
Raymond Meeks, jack Coyne,jacques Hajjar, Susan Bates, Kenneth
Romano, Thomas Szalkowski , jon Wardner, Victor Marino
THIRD ROW: Michael Lahood , Michael ancollas, joseph Zizzi ,
john Leddy, Ira Handler, Blackford Middleton

FROM LEFT TO RIGHT: FIRST ROW: Marvin McMillen , Sylvia Regalia, Leo
liO

Muido , Marguerite Dynski, Ben Echols, Lynne Hochberg-Pace,
Alan Calhoun
SECOND ROW: Marc Colman , Kenneth Anolik, William Cohen ,
Dennis Witehead, William Novak, Thomas Rosenthal , Henry
Tomiak , jack Cukierman , Paul Trautman , john Stubenbord,
Craig Blum, john Hedger, Michael Rade, Peter eumann , jack
Freer, Eugene Hirsh

CLASS OF 1980

CLASS OF 1990

FROM LEFTTO RIGHT: FIRST ROW: janice Errick , Alicia Stanton, Steven
Howard , Suzzette Robinson , Stephen Panebianco , Valerie Vullo,
Harriette Feier, Kimberly Blake, Dianne Jaeger Sutter
SECOND ROW: Marc Klementowski, joseph Murphy, Mary Rita
Murphy, Raymond Paolini , Robert Pitera , Mark agy , joyce
Paterson

FROM LEFT TO RIGHT: FIRST ROW: Thomas Dougherty, Archimedes
Thomas, Edward Rockwood, john Shayne, Constance Lentz ,
Coral Surgeon, Theresa Stephan- Hains, Mary George, Lynn
Steinbrenner
SECONDROW: james Twist, Margaret Paroski , Gaspere Geraci ,
Mark Borer

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�Porrath '61, pioneers integrated care for breast disease
STUDY SHOWS THAT HIS MAMMOGRAPHY CENTERS FIND BREAST CANCERS
EARLIER THAN THE AVERAGE FOR LOS ANGELES PATIENTS

aar A. Porrath, M.D., has known
since he was about four years old
that he wanted to be a physician.
"It was probably the influence of
traveling with my father when he
visited sick members of his congregation that influenced my early career
choice," Porrath explained. His father
was Rabbi Samuel Porrath, a long-time
rabbi in iagara Falls and Amherst.
Ironically, his inital decision to specialize in radiology was made because
he thought he didn't want direct contact with patients.
After graduating from the University
of Buffalo's School of Medicine in 1961 ,
he served his internship and residency at
Mt. Sinai Hospital in Cleveland. Following his military service as the chief of
radiology service at Kenner Army Hospital in Fort lee, Virginia, he moved to
California.
"It was while I was in los Angeles
that I started doing more and more
mammograms and I found that I liked
the patient contact," he recalled.
By 1983, his transformation to direct
patient clinical service was completed
when he founded the Women's Breast
Center in Santa Monica , which has pioneered an integrated care approach to
breast disease and management. In 1990,
he joined the Mammography Center in
Burbank. Both centers are operated under the umbrella of the Women's Breast
Center Group, which also operates the
Mobile Mammography Center in the
los Angeles area . Porrath also organized the Foundation for the Study and
Prevention of Breast Disease, which
sponsored a multitude of county-wide
health fairs , attracting more than

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250,000 people over the two-year period from 1985 to 1987. The two breast
centers are the largest providers of indigent breast health care outside of county
facilities in los Angeles; the foundation
has received grants to help cover the
costs of treating indigent patients.
"My book, A Multimodality Approach to
Breast Imaging, published in 1986, was
panned by some for being what was considered too clinical," explained Porrath, who is
obviously in opposition to these critics.
"Breast cancer is definitely increasing
- basically for two reasons. About 60
percent of the increase is due to the
aging of the population and the other
explanation is that we are simply detecting a lot more cancers," Porrath said.
He believes the current national controversy over the issue of mammogram
screening guidelines for women under
age 50 is largely related to cost issues.
Porrath points out that of the approximately 180,000 women who will

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get breast cancer this year in the United
States, nearly 30,000 will be in the 40 to
49-year-old age group. A total of 40,000
will be under age 50.
"If we send a message to the American
woman that screening has no validity, we
will virtually wipe out the detection of all
Stage 0 and Stage 1 breast cancers almost 20,000 women. There will be at
least 6,000 women who would have lost
the chance to prove that breast cancer is a
curable disease. That is not including the
vast number of people who will automatically jump at the chance of not having a
mammogram because of their innate fears
of breast cancer. "
Porrath acknowledges that detection is
more difficult in women under age 50,
but points out that the lead time between
detection and the spread of cancer is also
less- making early detection all the more
important. He stresses that breast cancer
in the younger woman is a much more
aggressive disease.

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�"Breast centers such as ours are actually quite cost-effective because our statistics from more than 40,000 patients
have demonstrated a significant reduction in unnecessary surgical biopsies. Of
course this reduction also means less
trauma for the patients."
Five hundred of the center's approximately 40,000 patients have been diagnosed with breast cancer. But a study
demonstrated that the cancers found at
the center were smaller and were found
earlier than those in other Los Angeles
breast cancer patients. For all of Los Angeles County, 62 percent of the patients are
Stage 1, I and II, compared to 90 percent of
the Women's Breast Center cancer patients who were Stage 0, I and II.
While he encourages breast self-examination, Porrath isn't optimistic that
its usage will increase greatly.
"Self-examination is based on a psychologically wrong principal- it offers
a negative reward for a positive action by
telling women that they can possibly
find breast cancer by examining themselves," he explains.
Porrath is well aware of the significant emotional issues involved in breast
examination, mammography and breast
cancer. His wife, Toni Bernay, Ph.D., is
a psychologist and a consultant to the
Women's Breast Center and the
Mammography Center.
Porrath has been elected a fellow of the
American College of Radiology and is past
president of The American Branch of the
International Society for Study of Breast
Disease, The National Consortium of
Breast Centers and current vice president
of the World Federation of Ultrasound.
He has taught radiology technology
training courses throughout the country, including Buffalo, and has lectured
widely on breast cancer and detection
issues throughout the U.S. and the
world, including Canada, Mexico , Germany, Argentina, Brazil, Greece and Austria.
+
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ILLIAMS

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cated last September, has received national attention and is being used actively for education and research.
A graduate of Western Reserve University, now Case Western Reserve University, he received a doctorate from the
University of Minnesota.
In receiving his Distinguished Medical Alumnus honor, Brody joins a list of
renown School of Medicine and Biomedical Sciences graduates. He will receive the award at a dinner in his honor
this October.
The SUNY Board of Trustees also
named Suk Ki Hong, M.D., Ph.D., UB
professor of physiology, distinguished
professor in january in recognition of
his reputation and contributions to research.
A UB faculty member since 1975,
Hong also serves as director of graduate
studies in the department of physiology. His research interests lie in the areas

Harold Brody '61,garners two
distinguished UB honors

arold Brody, M.D., Ph.D., has been
awarded the rank of distinguished
professor - the highest in the
State University of ew York system- and elected 1995 Distinguished Medical Alumnus.
The designation of distinguished professor, made by theSU YBoardofTrustees, is an order above full professorship
and has three co-equal designations:
distinguished professor, distinguished
service professor and distinguished
teaching professor.
Brody, professor of anatomy and cell
biology, was named distinguished teachingprofessor. Thedesignationisawarded to persons who have demonstrated
outstanding teaching competence at the
graduate, undergraduate or professional
level. Brody, who joined the
------·- =~
faculty in 1954, earned an
M.D. from the medical
school in 1961; for half of
his 41 years at UB, he served
as chair of the department.
He has done research and
published widely in the field
of neuroanatomy, and has
served on several editorial
boards, including that of BufHarold Brody, M.D., Ph.D.
falo Physician.
As a Fulbright scholar to
Denmark in 1963, he helped establish of renal and environmental physiology.
Hong has authored or co-authored
that country's first cadaver donor pronearly
190 articles for scholarly publigram. He was one of the founding members ofUB's Center for Aging and is past cations and more than 40 textbooks,
president of the Gerontological Society monographs and book chapters, earned
of America. He received the society's numerous academic awards, including
Robert W. Kleemeier Memorial Research the Stockton Kimball Award from the
Award for Outstanding Research in Ger- medical school for excellence in reontology in 1978.
search, education and service, and a
Brody left the anatomy department special citation for distinguished serchairmanship in 1992 to continue teach- vice from the japanese Panel on Diving
ing, do research and to fulfill a lifelong Physiology and Technology of the U.S.dream of establishing a Museum ofNeu- Japan Cooperative Program in atural
roanatomy at UB. The museum, dedi- Resources.
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....,

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�A

Spoonful

of

Humor©

Stu

Silverstein,

M.D.

e've all heard the old joke
about the man who calls in a
plumber and gets presented
with a bill for $400. The customer says, "That's outrageous!
What is your hourly rate?"
"$200 an hour, plus travel
And let's face it, men don't like calling
for help to begin with, but when you are
calling a plumber in, you are not only
admitting that you are asking for help,
but you are essentially saying that your
intestines need to attend a 12-step group.
That's not easy to admit to anyone, let
alone a guy who shows up in overalls, no
socks and asks to use your phone while
spinning a monkey wrench around his
pinkie (no l don't mean an orthopedist).
Why are all plumbers overweight?
Why do they all wear blue overalls. And
even if they aren't overweight they always wear double extra large overalls.
After jiggling the handle for 20 minutes

time," answers the plumber.
"$200 an hour!" the man replies, aghast. ''I'm a urologist. I
went to medical school, residency, did a fellowship and I
only charge $75 an hour."
The plumber just shrugs his
shoulders and says, "Hey, that's
all I charged when I was a urologist."
The disparity is even worse
for pediatricians, and I went

look. nobody hkes their job. That's why

through a similar experience
recently when I had to call in

they call it a"'job." If they loved it,

a plumber. Since I became a

they'd call it something else, like "fun."

homeowner, I can no longer just

"I love my fun." But if It was fun

call the landlord and order him

you wouldn't get paid for it.

over to the house when the
bowl is stuffed up.

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(billed through a lawyer's office) he tells
me l will need to replace the toilet.
A new toilet? ow that is something
you never think about.
How many folks have bought a new
toilet- ever?
And it's not that easy. The plumber
doesn't just say, "Okay, just fetch me a
toilet!"
You have to choose one from a catalogue that he hauls in from his truck.
A catalogue of toilets, now that's what l
call bathroom reading.
So now l have to choose between the
flashy, efficient model, and the standard, family one.
There you are having dinner with
another couple, and the woman says,
"You know, Myron and l are thinking
about trading in our Lexus LS for a
sporty LS 200. "
"Yeah, l know what you mean. My
wife and I are thinking about trading in
our toilet for an intestinal evacuation
system. You won't believe what they're
showing in the catalogue."
Of course everyone always complains that plumbers make too much.
Even doctors complain. lf you break it
down by the hour, the average plumber

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�charges more than the average therapist.
If I was a therapist and spent all those
years in school, I would just go an extra
six weeks and become a plumber.
What the heck! Combine your fields!
Put an ad in the yellow pages: "Purge
your drain and your psyche for one low
price. We'll even throw in the kitchen
sink."
"Copper pipes and crackpots - we
fix 'em all. "
"Whether you're anal-retentive or
your toilet is- no job is too small. "
"Unclog your drains and
your brains - aH our
plumbers are also licensed clinical psychologists. "
It would be great
the plumber
shows up with a
couch and you get
to stretch out and
free-associate.
"So, how do you feel
when your husband ignores you? ... hold on a second, damned tank won't release."
I suppose that being a plumber isn't
the greatest job in the world,
but then again what job
is?
Everyone wants a job
that they will like, so they go
to school for 200 years, borrow $200,000 and then they
realize that every morni'1g
they still have to go to
"work. " You can always
tell when people hate
their jobs, because
theygooutoftheirway
to tell you how much they
like it.
Look, nobody likes their job. That's
why they call it a "job." If they loved it,
they'd call it something else, like "fun ."
"I love my fun. " But if it was fun you
wouldn't get paid for it.
"Sorry Mr. Yakman. You're enjoying
your job too much. I'm afraid we're

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AcADEMIC HEALTH
PROFESSIONALS
INSURANCE
AssociATION

gonna have to stop paying you. "
When I tell people I am a pediatrician
and they say it must be "fun " getting to
"play with kids all day. "
o! I don't get to play with kids all
day. If you consider holding a kid
down while he screams, spits and sees
you as a human rest room with a white
coat, then, come along - it's play
time.
Nobody gets to play with kids all day
except other kids, and if you paid them

Insuring care for those who care

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Owned • Organized • Governed
PHYSICIANS • DENTISTS
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Academic Health Professionals
Insurance Association is a subscriber
owned and organized reciprocal
licensed by the Insurance Department
ofNew York State. Policy and programs
ofthe Association are determined by a
representative Board ofGovernors
elected by subscribers at SUNY
Health Science Centers.
Enrollment open at all times.
Transfers arranged without loss.
AcADEMIC HEALTH
PROFESSIONALS
INSURANCE AssociATION

to do it, eight hours a day and told them
they can't leave, they would hate it too.
In fact they would insist on going to
work.
+

Empire State Building
350 Fifth Avenue, Suite #1512
New York, ew York 10118
Ph. 212-947-4541
Fax 212-947-4572

Stu Silverstein, M.D., president of Stondup Medkine Seminars of Son froncisw,
Colifomio, lectures nationwide on humor inmedkine. He ~also c!Xluthor of What
About Me?, o book oboot growing up with odeveklpmentol~ disabled ~bling.

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THOMAS

3
MARCH

s

0
' 31 ,

of

Tacoma, Washington, has, in his
43 years of practice, tried pri-

vate practice in four locations in
New York State. He also worked
for

ew York State and the VA

before his retirement in 1973 at
age 70. With eight grandchildren and 10 great grandchildren,
he tells us he, at age 92, and his
wife, at age 75, are well (relatively!). He'd love to hear more
of his classmates from 1931.

white photography since he was

at 5 Country Club Lane, Route

medicine in addition to internal

14. He got involved in stereo

11,

photography about 22 years ago

shire 03257.

medicine and pulmonary diseases. He is director of respira-

ew London,

ew Hamp-

and began specializing in pho-

tory therapy services and associ-

1

tographic techniques that involve high-speed (l/50,000'h of

9

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has been

lab. Still actively practicing medi-

a second) electronic flash as well
as electronic sensors and elec-

a professor of pediatrics at ortheastern Ohio Universities Col-

cine, he enjoys skiing and fly
fishing. He writes that his son,

tronic components two years

lege of Medicine since 1985. He

George, is married and living in

ago. Dr. Stell uses two single-

KURT J . W E G N ER ' 52 ,

is director of the residency pro-

Chicago and has blessed him

lens cameras for his stereo work,

gram in pediatrics at Tod

with two grandchildren.

rather than the Stereo Realist

Children's Hospital in Youngstown, Ohio. Still active in pedi-

camera produced some 40 years
ago for that purpose. His spe-

atric consultations in neonatol-

cialization has paid off; he has

ogy and genetics, he has three

of Hol-

won numerous awards for his

sons, including one who is an

lywood , Florida, is understand-

stereograms, including the Best

orthopedist, and two grand-

HAR RY BERG MAN '34 ,

daughters.

Ann B. Matasar, Amoco Distin-

of Show medal from the Chicago Lighthouse International

guished Professor of Interna-

Exhibition of Stereo Photogra-

WILLIAM

ably proud of his daughter, Dr.

ate director of a sleep disorders

J.

S U LLIVAN ' 55 ,

IRVI NG S . K OLI N '65 ,

of Winter

Park, Florida, participated in a
national meeting of clinical investigators working with Revia
(naltrexone HCL) in the treatment of alcoholism. Revia is now
approved by the FDA for the

of

treatment of alcohol dependence. Dr. Kolin served as co-

tional Business at Roosevelt

phy for his strobed photograph

Los Angeles, California, is still

University, Chicago, who has

of a hummingbird at a feeder,

working full-time in forensic

investigator in the national

been elected American treasurer

the PSA Best Coniemporary

psychiatry, focusing on medical

study. He has also been ap-

of the International Federation
ofUniversityWomen Professors.

medal from the Wichita International Exhibition of Photog-

malpractice cases. He recently
became a member of the execu-

pointed to the advisory board of
Dupont Pharmaceuticals for fur-

She is that group's financial vice

raphy for his high-speed stereo

tive board, head of the psychia-

ther study of the drug's use

president, as well. Dr. Matasar

slide of a golf ball landing in

try section, of the American

in the treatment of alcohol de-

will visit Yokohama, japan, for

water, and the Best of Show

Board of Forensic Examiners.

installation before visiting the
group's official office in Geneva,

Salon for his stereogram portrait

Switzerland. Recently, the Uni-

of a young woman. Dr. Stell re-

versity of Paris- Sorbo nne, in-

members that during his medi-

an Innovation in Medical Man-

creased her yearly tenure from

cal school years, he and Ed

agementaward from The Ameri-

six weeks as professor of

Eschner were the only photog-

four

to

finance, and she received an invitation to serve as a visiting
professor of finance at the University of Kiev, Ukraine, as well
as one to lecture at the University of Vienna, Austria.

medal from the Cordova Stereo

Apter served as a resident ad-

tography. Stell, who retired from

junct professor at the oceano-

private psychiatric practice in
Eggertsville, New York, in 1975,

graphic center of ova University in Ft. Lauderdale, Florida.

has had an interest in black and

He has now taken a well-de-

has won

ies of the entire record of their
visit, which resulted in a reduction of health care costs due to a
substantial and sustained drop

cago and as a resource psychia-

ous awards for his stereo pho-

s

patients were given written cop-

turer at the University of Chi-

City, Arizona, has won numer-

0

Health Services program. In it,

practice, as a professorial lec-

Center. From 1984 to 1995, Dr.

6

can College of Physician Executives for his Brandeis University

tired in early 1984 from private

trist at Michael Reese Medical

9

HARRIS C . FAIGEL '60,

re-

of Sun

B ER NAR D S . S TELL '36 ,

1

raphers in the class.
N ATHANI E L S . APT ER '38 ,

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American College of Psychiatrists. The American College of
Psychiatrists includes only 550
members elected from the
40,000 members of the American Psychiatric Association.
Election to the College is based
on peer recognition of accomplishments; elevation to fellowship -

further recognition of

work in psychiatry- is achieved
by less than half of College
members.

in utilization of clinic services
despite increases in student en-

S AMUEL C . A RMSTRO N G ' 67 ,

rollment.

is serving as chief of staff of

GEO R GE B . P FO ERTNER ' 60 ,

Providence General Medical
Center in Everett, Washington.

of Boise, Idaho, was recently
board certified in critical care

served retirement and is living

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pendence, and was recently elevated to fellowship in the

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An internist, hematologist and
oncologist, he has been with the

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•
'

Everell Clinic there for 21 years.
JAMES L.

CAVALIERI

II

'69 ,

was recently awarded the Buffalo Pediatric Society's "Pediatrician of the Year" award. He's

Emory University. His son josh,

Medicine in the Bronx,

16, is getting ready to apply to

York.

falo Pediatric Society, he is a
member of the board of trustees
of The Children's Hospital of
Buffalo.

in private practice in physical
medicine and rehabilitation in

is l2 and his daughter julie is 10.

1

1972. Past president of the Buf-

9

8

Annapolis, Maryland. She and
her husband celebrated the birth

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of their second child, Margot

of Dover,

Leigh White, on April12, 1995.

Delaware, was recently elected

LiLLie Margot joins her older

to a fellowship in the American

brother, Cameron, who is 5.

MARKS . BORER '80 ,

Psychiatric Association.
MARITZA COTT0 '87 ,

of Dover,

IAN M . SCHORR '69 ,

ew jersey, writes that his twoyear-old grandson, who lives in
Chicago, forces him to take
much-needed short vacations!

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she is practicing cardiology at

that he is moving back East to
take a position in Columbus,

Rochester Park Medical Group
and Park Ridge Hospital in Roch-

Ohio with Ross Products Division - Abbott Laboratories, as
director of clinical research.

ester, ewYork. She tells us that
ANTHEA WOODLEY '87 , is also
practicing card iology and
CAMILLE BUONOCORE '87 , is

KEVIN FERENTZ '83 ,

of Balti-

more, Maryland, has a national

Brookline, Massachusetts, was

radio show heard on W EDAM in Buffalo and on 125 stations around the country. He
also has a new son, number three,

J.

TWAROG

'71 ,

listed in Best Doctors in America,
1994-95. He was also honored
by the Asthma and Allergy Foundation of America ew England Chapter- for his contributions to asthma care in 1995.

married and practicing endocrinology, and is the proud mother
of daughter Corinne.
GRETCHEN
EBERHART '87 ,

Noah Samuel, born january 25,

of Clearwater, Florida, has been
appointed medical director of
clinical affairs for Community
Dialysis Center. He writes that
although he has joined the ranks
of physician executives, he still
is able to enjoy a busy clinical
practice. Community Dialysis
Center operates 165 dialysis centers throughout the country.
EUGENE HIRSH '75 ,

is a prac-

ticinggastroenteroJogist in north
Atlanta. Elected chief of the Gl
section at St. joseph's Hospital
there for 1995-96, he is an associate clinical professor of medi-

1994.
is
in private practice with Tri-City

cine in digestive disorders at

Anesthesiologists in Tempe, Arizona, where he enjoys his busy
practice. He was recently board
certified in pain management.
He and his wife, jennifer, have

1

' 84 ,

9

9

finished

his residency in psychiatry at
Yale University and is now happily working in the Boca Raton
Psychiatric Group in South
Florida. His wife finished her
Ph.D. in psychology at the University at Buffalo in 1993 and
gave birth to their wonderful
son , Mitchell , on january 14,

of

Westchester, ew York, is assistant director of psychiatric emergency services at Mon tefiore
Hospital, the teaching hospital

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Claire Anita, on December 3,
1994. She joins her two brothers,
Ryan, 2 1/2 and Connor, 1 1/2.
KRISTA M . ( PRIGG) KOZACKI
'91 ,

of Florence, South Caro-

lina, wonders how everyone is
doing in Buffalo. She writes that
after she finished her fami ly
medicine residency, she opened
a private practice with another
physician she went through residen cy with. They call the practice, "Pee Dee Regional Family
Medicine." Business is great,
she says, and the art and thrill of

join them in September. Her family is doing wonderfully: her husband continues to practice with
the same law firm , and their
twins, Stefan and jacob, turned
two February 18. They talk nonstop, climb the five-foot fence,
play in the dirt and give wonderful hugs. Unique to her practice
is a nursery built into the office

of

daughter, with a private nanny
to care for the children. "It's the

ew York and his wife,

best part of medicine and moth-

DOUGLAS P . PREVOST '90,

of the Albert Einstein College of
B

Anita, had their third child ,

for her boys and her partner's

1995.

Snyder,

Stefan and Jacob Kozacki, 2

family medicine are even more
fulfilling. A third physician will

s

0

BRIAN FELDMAN '90,

for a girl?? " jennifer sends her
best regards to Dr. aughton.
She was his secretary in 1983
and 1984.
WEINST E IN

is doing a fel-

on january 27, 1995.

four boys: Matthew, 7; Brendan,
5 1/2; justin, 4; and joey Jr., l.
"Anyone have the secret formula

CAROL

PANKOW

lowship in endocrino logy at
Massachusells General Hospital
in Boston. She and her husband
celebrated the birth of their first
child , Lindsay Grace Eberhart,

JOSEPH D . CURLETTA '84 ,
CHARLES J. MCALLISTER '73 ,

writes that

writes

ROBERT SHALWITZ '80 ,

of

FRANK

is

SARAH MURRAY WHITE '85,

coaches basketball. His son Ben

been in private practice in
Williamsville, ew York, since

I

ew

colleges and is in his third year
of varsity swimming. He also

.

s

m

m

e

�•

.......................................

.

BACK TO
SCHOOL
SALE

I

erhood," Krista says. "Finally,
it's very exciting to hear and
read all about the growth and
changes at UB med."
CYNTHIA ( LEBER MAN) JENSON

of Pittsburgh, Pennsylvania, writes that she and Mark

'92 ,

had a baby girl, Alexandra
Nicole, on March 8, 1995. She
also tells us that jim and Laura
Krug had a baby girl, Sarah Eliza-

R ICHARD WARREN BR ITT ' 36 ,

died last ovember 4, in Deer
Isle, Maine. Dr. Britt, a
Tonawanda, ew York, native,
was the son of Dr. W. Warren
Britt. He began his medical career in practice with his father
and brother, DR . ROBERT C .
BRIT T ' 42 , in Tonawanda, and
practiced there for 29 years,
where he was a member of the
medical staff of DeGraff Memo-

beth.
CATHY K . NAUGHTON '93 ,

and

MICHAEL J . NAUGHTON '93 ,

are now second-year residents
in the general surgery and internal medicine programs at Washington University/Barnes Hospital. Michael will pursue a fellowship in hematology/oncology
and Cathy will continue at Washington University in the division of urological surgery. Cathy
and Michael were married September 3, 1994, in St. Louis,
Missouri, at the inth Street
Abbey in historic Soulard.
T O DD S C H LES ING E R ' 94 , is
completing an internship in internal medicine and beginning
one in dermatology this summer.

J O HN

OBITUARIES

TIM OTHY

SH E RWOO D

recently completed an internship in internal medicine at
johns Hopkins Hospital. He
plans on making a career change
to general surgery and will start
an internship at University Hospitals of Cleveland, Ohio, this
'94 ,

summer. He and classmate Debra
Tarantino '94, will be married

Performa 5200 CD

Performa 636 CD

rial Hospital, before moving to
Maine in 1966.
IRVI NG WEINER '37 , died May
6, 1994, at age 82. He had been
in private practice in ewburgh,
ew York, since 1938, before he
retired after 50 years of practice.

L EON A RD WOLIN ' 41 ,

PowerBook 520

of Buf-

Power Macintosh
7100CD
$1379

Performa 636 CD

falo, died May8,1995. Dr. Wolin
was the father of DR . MAU R ICE

8MB RAM, 500MB hard drive, CO-ROM drive, 15" color monitor, keyboard, mouse and lots of software.

Performa 5200 CD

$1819

8MB RAM, 800MB hard drive, CO-ROM drive, 15" color monitor, keyboard, mouse and lots of software.

W OLI N '84 .

Power Macintosh 71 00 CD

$2029

8MB RAM, 700MB hard drive, CD-ROM dnve, 15" color monitor, keyboard, and mouse.

died
unexpectedly on Christmas Day
while visiting his daughter in
Colorado.

THOMAS J . ENR IGHT '48 ,

WA L TER

A.

PowerBook 520

$1469

4MB RAM, 240MB hard drive.

PENTIUM NOTEBOOK
DELL Pentium NoteBook
$4089

OLSZEWSK I ' 54 ,

died February 23, 1995. An assistant professor of neurology
and clinical associate professor
of anatomy and pathology at UB,
Dr. Olszewski was board certified in neurology by the American Board of Psychiatry and
eurology and neuropathology
by the American Board of Pathology. He was a fellow of the
Stroke Council of the American
Heart Association and the American Academy of eurology.

16MB RAM, 810MB hard drive, 75MHz, 10.4" Dual
Scan Color Display , Li ion extended life battery.

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~

,,

\!~L ill.\\

- OFFICEI

September 16.
A non-profit University program for students, faculty &amp; staff
The Commons • North Campus • (716) 645-3554 • Fax: 645-3884

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�BUFFALO PHYSICIAN

Non-Profit Org .
U.S. Postage
PAID
Buffalo, NY
Permit No. 311

STATE UNIVERSITY OF NEW YORK AT BUFFALO
3435 MAIN STREET
BUFFALO NEW YORK 14214

ADDRESS CORRECTION REQUESTED

PLANTING

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�</text>
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                    <text>State University of New York at Buffalo School of Medicine and Biomedical Sciences, Spring 1995

�BUFFALO PHYSICIAN
Volume 29, Number 2
ASSOCIATE VICE
PRESIDENT FOR
UNIVERSITY
SERVICES
Dr_ Carole ~milh Pctrl,

Dear Alumni cnl Friends,

I

DIRECTOR OF
PUBLICATIONS
TunOih) ). Conroy
EDITOR
Nant'tlc Tramont. R.
ART DIRECTOR
Alan J. Kegler
ASSOCIATE ART DIRECTOR
D.mdj. Riley
PUBLICATIONS MANAGER
)ud,on Mead
PRODUCTION MANAGER
t\nn Raszm.,mn Brov.n

STATE UNIVERSITY OF
NEW YORK AT BUFFALO
SCHOOL OF MEDICINE
AND BIOMEDICAL
SCIENCES
Dr. John augh1on. Vice President
f"r Chnit:al Affa~rs. Drm1
EDITORIAL BOARD
Dr. john A Richert, Chairman
Dr. Rus.sdl Besseuc
Dr. Martin Brecher
Dr. Harold Brod)
Dr. Richard L. CoUnts
Mr. Ra,; Desai
Dr. Alan]. Drinnan
Dr. james Kanski
Dr. Elizalxth Olmsted
Or. Barbara Majeroni
Or Charles Paganelli
Da·. Thomas Raab
Dr. Stephm Spauldmg
Dr. Bradley T. Truax

t's a tremendous pleasure to inform you that UB's medical school was among those
institutions to receive one of the last gram awards to be funded by the Lucille P. Markey
Foundation. The faculty leadershtp who led thts successful effort, Dr. lam Hay and Dr.
Philip LoVerde in particular, deserve the institution's gratitude for the quality of the
grant proposal submitted to compete successfully in this national arena. The timing of the
award and its announcement could not be better. For example, this issue of Buffalo
Ph~ ~ician emphasizes research activity in the school; the new biomedical research
building opens this ~pring; and the Sesquicentennial activities are
upon t•s.
Although scientific merit was the primary criterion on which the
I~
Foundation based its judgment. the school was certainly benefitted by
' . ~the enthusiastic support and hard work of the University's administrative officers; many of our alumni, especially Dr. Thomas Frawley,
Dr. Virginia Weldon and Dr. Eugene Farber; and the many faculty
who helped make this multidisciplinary effort a success. The funds
from this award will be used to develop further the school's commitment to the area of molei:ular parasitology. It is a tremendous tribute
to the school that the core of this program will be administered bv a basic science
department that has had significant historical import to the school, Mi~robiology. Thus.
the Center will serve to perpetuate the memory of Dr. Ernest Witebsky, the founder of the
department at UB, and his protege who served the school so well, Dr. Felix Milgrom. Both
of these outstanding scientists provide the ideal role models for their successors to
emulate. All in all, the Markey Award designation to UB was a great event and marks UB's
further commitment to pursue its scientific missions in the years ahead.

~·4-.~

john Naughton, M.D.

Vice President for Clinical Affairs
Dean, School of Medicine and Biomedical Sciences

TEACHING HOSPITALS AND
LIAISONS
The Buffalo General Hospital

Michael Shaw
Buffalo VA Medtcal Center

ArlawKclly
The Children's Hospital or Buffalo
Erie County Medical Center
Mercy Hospital
Millard Ftllmore Health System
friDIItSava
Roswell Park Cancer Institute
Sisters or Charity Hospital
Dennis McCardt.Y
() The State Unlverllry of New York
at Bullalo

IJuffalo Physiclo is pu!Jhshed
quanerly by the State Un.iverslry of
ew York at Buffalo School of
Medictne and Blomedial Sciences
and ~ Office of Publications. It is
sent, fret: ofcharge. to alumni, fill:ulty,
students, tcildrnts and l'rlendi.. The
staff reserves~ ri&amp;htto edit aD. copy
and •ubmisslons accepted for
publication.

Address questions. commmts and
submisstons 10. Eduor. Bllffl&amp;lo
Physician, State Umversuy of New
York at Buffalo, University

Publicauons, 136 Crofts Hall, Buffalo.
New York 14260; or by e-mail to
notes@pub.buffalo.edu.

s.-. ....., ..... tc

Buffalo

Physician, 147 CfS Addition, &lt;05
MainStrttt.BulTalo,NewYork Iilli

0. Felew Alanlli,

A

s winter begins to fade and the first suggestions of spring appear, our attention can
tum to the upcoming Spring Clinical Day.
By this time, we on the Board sincerely hope that you have responded to the
AlumniOfficeandarernakingplanstorenewfriendshipsandparticipateintheSpring
Clinical Day program.
The sub-committee of the Board has been reviewing files and
several members from the class reunion years will be chosen for
Achievement Awards.
The senior medical student class will be honored at an upcoming
cocktail reception and we look forward to officially recognizing these
new members into the Alumni Association.
Once again, we look forward to seeing you at Spring Clinical ay.
If there are any matters which we can assist you with, do not hesitate
to contact the Alumni Office.

Russell W. Bessette, D.D.S., M.D. '76

Prnident. Medical Alumni Association

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Research
FDA chief David Kessler delivers
Harrington Lecture. Page 20.

Hospital News
Building the Future of Research

UB's new
research building brings together researchers
in a way designed to produce results far
beyond what they can accomplish alone.

Restructuring Research at UB

The reorganization of
scientists and clinicians promises synergistic
results.

Medical School
Then and Now
ASpoonful of Humor
Alumni
Classnotes

Garden Spots ECMC' s roots. Then
and Now. Page 24.

�E J ··························································································

Landmark UB study shows major
illness in West Side population
esidents of Bqffalo's low-income,
largely Hispanic Lower West Side
are twice as sick as the U.S. population living in poverty, and face
major barriers to receiving adequate health care, according to a
comprehensive health survey conducted
by the UB Center for Urban Research in
Primary Care.
The study is one of the first of the
health status of a pocket of the urban
poor in general, and of an urban Puerto
Rican population in particular.
The study is also one of the first of
Puerto Ricans, who account for threefourths of Buffalo's Hispanics and comprise the major portion of Hispanic populations in ortheastern cities. "Most existing studies of Hispanics have been done
with Mexican-Americans in the Southwest and West," said Carlos Roberto jaen,
M.D., Ph.D., study project director and
UB assistant professor of family medicine
and social and preventive medicine.
Demographics from the study show
the population to be 54 percent Hispanic (three-quarters Puerto Ricanborn) , 29 percent non-Hispanic white
and 17 percent African American. The
number of men and women are nearly
equal. Seventy percent are under 40.
Smoking, alcohol consumption,
asthma and diabetes are major problems
in this population in which conventional written health information isn't
very useful because more than a third of
the residents did not complete high school.
And when members of the Hispanic
population go to a hospital or doctor's
office in Buffalo, they often can't communicate with the English-speaking staff
and physicians, the study noted.
The results also indicate that, contrary to early assumptions, most residents of this low-income neighborhood
have access to health care and are cov6

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Carlos Roberto Jaim, M.D., Ph.D., UB assistant professor and West Side study director.

ered by some type of health insurance.
Bilingual interviewers went door-todoor to gather data for the study, completing interviews at 826 households
representing 1,873 individuals, for a
response rate of about 78 percent.

UB-Roswell researchers win $8.9
million in grants from NCI
rants totaling $8,914,038 have
been awarded by the ational Cancer Institute to UB and Roswell
Park Cancer Institute researchers.
john A. Blessing, Ph.D., UB adjunct assistant professor of statistics of the statistical office of the gynecology oncology group at Roswell, won
a five-year $7,514,692 grant to fund that
group's ongoing work of collecting and
correlating data.
Margot M. Ip, Ph.D., UB research professor in Roswell's department of experimental therapeutics, won a fouryear, 734,752 grant to investigate gene
expression in normal mammary cells
and try to determine the way this expression is disrupted by malignancy.
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Enrico Mihich, M.D., of Roswell's
department of experimental therapeutics, won a three-year, $342,763 grant
to study cancer chemotherapy and immunologic effects. The research will expand previous in vitro work on Adriamycin
and examine its effects in vivo.
Thomas Shows, Ph.D., UB research
professor from Roswell's department of
human genetics, won a three-year,
$321,831 grant to clone chromosome 11
genes.

Questions raised about use of
growth hormone for short stature
ost short children are well-adjusted and have no serious social
or emotional problems, despite
assumptions by some physicians
and parents, a study by researchers at UB and The Children's
Hospital of Buffalo shows.
The research hits at the heart of the
controversy over whether to treat short
children who are not deficient in humangrowth honnone. One rationale to treat
was to improve psychosocial functioning.
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"Shorter-than-normal children may
be teased, and they may be treated as if
they are younger than they are, but,
despite that, they are doing pretty well,"
said David E. Sandberg, Ph.D. , assistant
professor of psychiatry and pediatrics,
B has won a new three-year,
and lead study investigator. "Previous
600,000 grant from ASA to
reports had led us to believe these chilstudy the physiological mechadren were quite bad off."
nisms behind observed cardiovasThe study, published in last
cular regulatory phenomenon in
December's issue of Pediatrics, is based
zero-gravity.
on data from 258 children referred to a
The award is based on research conpediatric endocrine clinic because of ducted on cardiovascular functioning
shorter-than-normal stature. Parents and deconditioning in microgravity on
completed a Child Behavior Checklist; two ASA Space Lab flights that found
children 12 years of age and older com- blood pressure in flight is regulated by a
pleted a comparable questionnaire them- decrease in vascular resistance in reselves. Responses were compared with sponse to an increase in cardiac output
those from normal children and chil- induced by microgravity.
dren referred for mental-health services.
This phenomenon was first observed
Earlier studies reported problems in UB research
among children with moderate to severe
short stature, including socialization based
on height rather than age, stigmatization because of appearance, poor
social skills, social isolation, low
self-esteem and poor academic
achievement. But these data
were primarily from short children with conditions such as
underactive pituitary or chromosomal anomalies.
The UB study showed that parents rated boys somewhat less socially competent with somewhat
more behavior problems than the normal sample, but without major ·~
psychosocial problems. The short boys ."~
were rated as functioning disor
tinctly better than the group referred for mental-health services.
Boys' ratings of themselves mirrored their parents on social activ: -~
ity, but they didn't report having more
behavior problems. Short adolescent boys
rated themselves better athletically than conducted on Space Lab l.
Findings in the second study, conother boys their age. Short girls showed
little difference in social functioning, be- ducted on Space Lab 2, also showed that
havior problems and self-esteem and re- the ability of astronauts to perform work
ported being better at athletics than the when they returned to Earth, as meacomparison group.

UB wins $600,000 NASA grant to
study BP regulation in space

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sured by performance on a specific physical-exercise regimen, was decreased, and
that there was a relationship between
the ability to perform work and time
spent in space.
Astronauts on Space Lab 2, who were
in flight for 15 days, performed less well
upon their return to Earth and remained
limited longer than their counterparts
on Space Lab 1, in flight for nine days.
Both in zero gravity and in readjusting to Earth's gravity, the astronauts'
bodies regulated blood pressure by expanding or constricting blood vessels in
the presence of increased cardiac output, the results showed, a phenomenon
not observed prior to the two UB Space
Lab experiments. The experiments and
equipment used on both Space Lab experiments were designed by Leon E.
Farhi, M.D., UB
dis tin-

· guished
professor of physiology.
The new experiments,
Farhi said, will be conducted in simulated zerogravity environments. "If we
find something interesting
through these Earth-bound experiments," he added, "we will go back to
ASA for another in-flight experiment."
UB researchers involved in the project,
in addition to Farhi were Barbara E.
Shykoff, Ph.D.; Christopher Eisenhart;
Richard Morin; Albert]. Olszowka, M.D.;
David R. Pendergast, Ph.D., and Mary
Ann Rokitka, Ph.D.

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said, "john has demonstrated a remarkable ability to keep
Buffalo General in a
leadership position
in today's increasingly complex health
care scene.
"With the advent
of health care reform
Kinnard
and the need to develop integrated
health care systems, John's business acumen and creativity will serve General
Care Corp. and the hospital well in the
years to come."

Butfalo General'sKinnard and
Friedlander assume new roles
fter serving as president and chief
executive officer of General Care
Corporation since its founding in
1985, William V. Kinnard, M.D.,
has stepped down to devote more
time to his role as president and
chief executive officer of The Buffalo
General Foundation.
Succeeding Kinnard is john E.
Friedlander, president and chief executive officer of The Buffalo General Hospital, the main entity within General
Care.
ln making the announcement, Thomas R. Beecher, Jr., chairman of the
General Care Corp. board of directors
said that Friedlander, a BGH executive
since 1984, will maintain his responsibilities as the hospital's president and
CEO.
Beecher described Kinnard and
Friedlander as "exceptional leaders
whose vision and achievements have
earned them the respect and admiration
of their peers in the health care industry."
Kinnard, who relinquished his General Care Corp. responsibilities last September, noted that the move had been
planned for some time. Kinnard had
served as BGH president and CEO from
September 1975 until March 1990 when
he was named the
hospital's first fulltime board of trustees vice chairman.
He will continue as
chairman of the
board of directors of
Friedlander
WestLink Corporation, a for-profit joint venture involving
General Care and several other Western
ew York health care providers.
Commenting on Friedlander's appointment to lead General Care, Beecher

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work more closely with the most visible
and respected provider of health care
services in the West Side community.
"This merger will enable Buffalo Columbus and Buffalo General to jointly
develop a strategic direction toward providing a comprehensive array of primary ambulatory care services to address the major health problems in the
Hispanic and non-Hispanic communities of the West Side," he added.

BGH first WNY hospital to oiTer
endoscopic ultrasonography
he Buffalo General Hospital now
performs endoscopic ultrasonography (EUS), a new diagnostic technique that detects Gl
tract tumors with greater accuracy.
The technique provides higher resolution images of tumors within the Gl
tract and its adjacent structures.
Buffalo General is the only hospital in
Western ew York to offer the new
technique, according to Siddhartha
Shah, M.D. , UB clinical assistant professor of medicine.
"With EUS , a detailed five-layer
structure of the gastrointestinal tract
wall can be easily visualized," Shah
said. "GI tract tumors distort this normal five-layer structure and can be
detected by this new technique , in
detail. It allows us to visualize with
great accuracy how far the tumor extends through and beyond the wall
and whether it involves lymph nodes
and adjacent structures.
Shah said EUS is superior to CT scanning in staging GI malignancies, with
EUS accurate in more than 85 to 90
percent of cases and CT accurate in
about 50 percent.
The procedure takes one to two hours
and is performed in BGH's GI Laboratory, usually on an outpatient basis.

Buffalo General and Columbus
Hospital begin merger talks
n a move designed to improve the
delivery and expand the scope of
health care services to Buffalo's West
Side, the Buffalo Columbus Hospital, its parent organization, Buffalo
Healthcare Corp., and The Buffalo
General Hospital have agreed to engage
in discussions that will result in a plan
to merge.
Buffalo Columbus president and chief
executive officer Andres Garcia described the discussions as a "dynamic
opportunity" for the hospital to
strengthen its position as the "pre-eminent provider of primary, ambulatory
care and substance abuse services for
the Lower West Side.
"Our aging facility and equipment
have made it increasingly difficult for
Buffalo Columbus and Buffalo
Healthcare Corp. to provide the Hispanic community and all people on the
Lower West Side with the health care
services they expect and deserve," Garcia
said.
john E. Friedlander, Buffalo General
president and chief executive officer,
said BGH "welcomes the opportunity to

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ECMC officials hope the new facility
will provide simpler and faster services
for outpatients using the hospital, including dedicated parking, decentralized, "point-of-service" registration and
improved patient flow from one service
to another.
The facility would be funded through
the sale of general obligation bonds,
with ECMC contributing about $2 million, based on the level of surplus hospital officials expect for 1994. The twostory structure will be the first construction project at the medical center since
it was built in 1978.

Patients are given intravenous sedation.
Routine endoscopy locates the tumor
and the dedicated ultrasound endoscope
examines the area.

Feeley named associate director
at Buffalo VA Medical Center
illiam F. Feeley has been named
associate director at the Buffalo
VA Medical Center. He will be
responsible for all administrative support services at the facility , including human resources, medical ad- .---------.
ministration , fiscal
and acquisition and
rna teriel management. The position
reports to medical
center director Richard S. Droske.
Prior to coming to
Buffalo, Feeley held
associate director
positions at the VA
Medical Centers in orthampton, Massachusetts, and Grand Junction, Colorado.

Hospice Buffalo receives training
grant to support its CHILD Project

fficials at the Erie County Medical
Center have announced plans to
build a $14 million ambulatory care
center r.ext to the hospital.
The 80,000-square-foot building
will house primary care, diagnostic and specialty outpatient services including family and internal medicine,
OB-GYN , pediatrics, chronic dialysis,
laboratory specimen collection stations
and X-ray facilities.
The hospital submitted a CO last
December.

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they support families in their communities.
The CHILD Project team will define
conditions of infants at risk and teach
others to recognize these risk factors in
order to appropriately refer or care for
the infant. Project training will include
the medical and psychosocial aspects of
the problems of prematurity, cocaine
exposure, HIV/AIDS, sickle cell anemia,
developmental disabilities and failure
to thrive.

Buffalo General announces ED
renovation and expansion project

he Buffalo General Hospital has
unveiled plans for a $5.6 million
renovation and expansion of its
he ew York State Department of
department of emergency mediSocial Services has awarded Hoscine.
pice Buffalo a $42,000 grant to
John Friedlander, BGH presiprovide informational and educa- dent and chief executive officer, detional programs designed to im- scribed the project as the "most signifiprove the provision of services to cant construction program" for the hosdisabled infants with life-threatening pital since the mid-1980s when the new
conditions. Hospice Buffalo is one of 16-story medical tower building was
only two organizations in ew York completed.
State to receive grant funding for this
The project, to be accomplished in
program.
phases so as not to disrupt ED operaThe grant was awarded to Hospice's
tions, is expected to be completed about
CHILD Project, a special program intro- mid-1996 .
duced in 1994 as part of a ew York
The initial phase will involve conState Department of Social Service spon- struction of a two-story addition on the
sored initiative to improve services to Ellicott Street side of the ED , including
medically frail infants who are at risk of
a new elevator to operate between the
medical neglect. The grant will be ad- ground floor and the first floor of the
ministered by The Life Transitions Cen- main hospital building.
ter, an agency affiliated with Hospice
Renovation of the first floor , previBuffalo that provides education, counously occupied by same day surgery,
seling and support groups for children,
will occur during the project's initial
adults and families concerned about
phase. In June or July of this year, ED
grief, death and living with a serious or
operations will move from the ground
life-threatening illness. The program,
floor to the first floor until renovations
which began this month, will continue
are complete.
through February 1996.
Temporary relocation will ensure
The CHILD Project will assist and
uninterrupted service for the more than
support social services professionals as
3,000 patients who use the ED.

ECMC submits CON to build $14
million outpatient care center

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PHOTOS BY K.C . KRATT

�UB's new research building brings together researchers in away
designed to produce results far beyond what they can accomplish alone

BY

SCOTT

THOMAS

It looks sharp. It's built for speed
-everything within ready reach, all the amenities for
comfort and efficiency. It's roomier than you'd expect
from the outside.
You might say the new research building of the
School of Medicine and Biomedical Sciences is a
luxury vehicle perfect for the next stretch of the
scientific highway.

The new laboratories combine functionality with beauty in a classical design.

�The new building features standard. institutional-quality
materials used in an innovative and visually pleasing way.
Light-reflective materials open up the interiors: maple casework makes the workspace bright and inviting.

THE RESEARCH BUILD! G is in the final stages of
completion, culminating a project more than five years in the
making. The building provides for 60 wet laboratory units ,
each consisting of a main lab and two auxiliary labs; support
facilities such as equipment rooms , utility rooms, darkrooms
and "environmental chambers" for heated or chilled materials ; 60 offices for investigators; and six spacious conference
areas.
It's a significant advance for a school whose progress in
research- one of the most significant factors in attracting
and keeping high-quality faculty members - had been
squeezed by a severe shortage of laboratory space.
"It was essential that we make a sizable space readily
accessible and functional very quickly ," says Bruce A. Holm,
dean for research and graduate studies at the medical school.
A faculty member throughout the time the building was
being planned, Holm moved to the dean's office in 1993.
joseph T. Spence , Ph.D. , Holm's predecessor as dean for
research and graduate studies, was heavily involved in helping researchers, administrators and building planners reach
a consensus on just what form the new structure should take.
"We very much saw the building as a tool , just as any piece
of equipment in the laboratories is a tool, " said Spence, who
left UB in january 1993 to become head of the Beltsville
Human utrition Research Center, a division of the U.S.
Department of Agriculture's Agricultural Research Service.
"We tried to be one step ahead of where we were today,"
Spence said. "We asked ourselves what people would be

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doing five, 10, 20 years down the road. And we were
particularly interested in coming up with some design concepts that would make it as flexible as possible. "
The existing labs in the Cary-Farber-Sherman (CFS)
complex, Holm said , not only were inadequate for the
number of researchers working , they needed major renovations to bring them up to state-of-the-art standards. "The
problem with that," he says, "was that with the laws concerning asbestos abatement, it was incredibly costly to renovate
those labs. We actually found that it was cheaper to build the
new building. " The old labs will stay, he added , and "we will
renovate them , but now we can do it in more of a piecemeal
process. "
After a competitive bidding procedure, the architectural
firm Helmuth Obata Kassebaum was commissioned to design the building and supervise its construction. HOK is
well-known in architectural circles - primarily for its
sports facilities , including Baltimore's baseball stadium,
Oriole Park at Camden Yards, Buffalo's Pilot Field and UB's
University Stadium.
Andy Wong, a principal at the ew York City office of
HOK , served as the firm's project manager for the research
building, leading a core team of three architects. He says the
job involved drawing people out on what they wanted just as
much as it did drawing lines on blueprints.
"We understood that the mission of this project was to
create more research space," Wong says. "The ability of the
institution to attract research grants and talent is really tied

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�Maintenance-free materials were used to provide longevity as
well as workability. Amenities include special flooring. Corian
countertops. vinyl wall coverings and granite flooring and
sculptured steel walls inthe main elevators.

"Ultima tely, a lab bui lding is about the environment in
into that. But that doesn't begin to define the goals of the
the lab ," he says. "It's about the research environment that
project, everything that's wrapped up in the warm fuzzy
surrounds the investigator. It doesn't work from the outside
stuff, the qualitative issues that need to be addressed. "
in,
it works from the inside out: how the benching works,
In a series of dialogues with investigators and other
how much wet space there is , how that relates to service
faculty , school and campus administrators and State Univerrequirements ...
sity of ew York representatives, the planners defined
"We began to get a sense of the
some of those qualitative issues. Says
academic day there (among
Wong: "They ranged from the
researchers) , what the
global - 'We have X numculture is there. We
ber of dollars , get us the
"THE MISSION of this project was to create more research
discovered
that
most laboratories posspace.
The
ability
of
the
institution
to
attract
research
grants
and
talent
is
really
tied
to
people don' t really
sible' - to the more spewant to hang around
cific- 'We don't have a
that But that doesn't begin to define the goals of the project. everything that's wrapped
in a public space sq
front door to this acaup in the warm fuzzy stuff. the qualitative issues that need to be addressed."
much as have convedemic complex, and we
nient access to their serwould like to create that. '
vice areas. They tend to spend
"The end product, the building,
more time in their research environthe attributes of the building- its modument than in the public rooms. The culture of research is
larity, its flexibility- you just can't take that off the shelf and
more that they need to be in their own spaces. But we built
say, 'Here it is.' You have to tailor those generic approaches,
and that includes siting, circulation , connectivity to the
it to encourage interaction. For example, the conference
existing campus, landscape issues, future connectivity. The
rooms are in an area where there's a lot of circulation. "
CFS complex is a pretty Byzantine maze of things. We didn't
That kind of thinking is evident in the design of the
want to aggravate the circulation issues, we wanted to clarify
completed building. It's eight stories, including a ground
them. "
floor , six floors that house laboratory and office space, and a
And primarily, Wong said , they talked about how to make
penthouse floor with mechanical equipment for the buildthe building work best for the people whose work it was
ing. The laboratory floors are laid out identically to each
intended to further: the researchers themselves.
other- labs , offices, support rooms and conference rooms

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�Outside the laboratories, the floors are built for convenience and easy functionality. Support rooms and equipment rooms hold excess materials and equipment, freeing up
space in the labs. Each floor has two darkrooms for developing photos and X-rays; the darkrooms are at one end of a long
corridor, but an indicator light in the center of the hall shows
whether the darkrooms are in use- saving busy researchers
the long walk to find that out.
In addition, dozens of small touches make the research
building a comfortable place to work.
"We had to use very maintenance-free materials, materials that have longevity," says architect Wong. "We were
really challenged, because normally that grade of material is
not one that the (construction materials) industry features or
focuses on to try to come up with a lot of new colors or
patterns. Our challenge was to use it in as innovative and
visually pleasant a way as possible.
"We did that by choosing very pleasing patterns on the
floor, in the tiles. We took the standard, institutional-quality
things and used them in a different way. We introduced
daylight into the corridors by the placement of the windows.
We chose to use as light-reflective materials as possible to

all located in the same place, making it easy to find one's way
around and easy to service the heating/cooling, electrical,
water, waste, fiber optic and other supply and disposal lines.
The labs themselves combine functionality with a large
degree of beauty. Each laboratory unit consists of a large lab
space (some with a center island) and two smaller adjacent
labs where auxiliary or preparatory work can be done. There
are the usual assortments of taps for purified water, natural
gas and air. The countertops are a black epoxy resin, built to
simulate the old slate tops that researchers have used for
centuries.
Fume hoods allow for work with materials that need to be
vented to the outside. (ln addition, positive air pressure is
maintained in the corridors, and negative in the rooms
themselves, to prevent potentially hazardous airborne materials from escaping into common areas.) Solid maple cabinetry
inset with glass windows gives a classical feeling to the
rooms.
Across the hall from each lab unit is an office space of
about 14 by 15 feet; every office has a window, recessed over
the attractive maple veneer that conceals the room's heating!
cooling unit.

The building completes a circuit with
the Cary-Farber-Sherman complex and
connects Squire and Harriman halls
through tunnels and overhead walkways. The buildings now enclose a
quadrangle of grass. ringed by sidewalks and crisscrossed with lights.

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working with microbes or hazardous chemicals, but it can be
open up the interiors. ln the labs, the maple casework was to
costly in terms of heat loss.
make it as bright and as inviting a space to be in as possible,
To alleviate that costly loss, exhaust air passes over a
because people spend a great part of their day there."
series
of pipes containing glycol; the heated glycol is then
Thus, such amenities as chalkboards scattered throughrecirculated from the top floor down to the
out the corridors for impromptu brainstormbasement, where it heats the incoming sessions, Corian countertops
ing fresh air. "lt probably traps
in the restrooms, vinyl wall
one-third to half of the heat
covering in a pattern of
that would otherwise be
"Ultimately. alab building is about the environment in the lab. It's about the
tiny squares, special
lost," Krygier says.
flooring in the first-floor
research environment that surrounds the investigator.lt doesn't work from the
In addition , to save
animal holding areas beelectricity,
lights in the
outside
in.
it
works
from
the
inside
out
how
the
benching
works.
how
much
cause it's continually
building
are
controlled
being washed down and
wet space there is. how that relates to service requirements."
motion
sensors
- no
by
beautiful granite flooring
need
to
remember
to
flick
and sculptured steel walls in
the switch off when you leave. And
the two main elevators add a sense of
a sophisticated reverse osmosis water purification
comfort and beauty as well as functionality.
system treats tap water to remove sediments and bacteria by
just as notable is the environmental consciousness that
forcing it through a screen at high pressure, running it
went into the building's design.
through a charcoal filter and submitting it to ultraviolet rays.
The air in the building is renewed nine times per hour,
On the outside, the building completes a circuit with
says Theodore R. Krygier, project coordinator for the
the Cary-Farber-Sherman complex and connects Squire
University's Office of Design and Construction. That's necand Harriman halls through tunnels and overhead walkessary for safety, in a building where investigators might be
ways. (A passkey card system will secure the laboratory
floors against intrusion from the common pedestrian
corridor. ) The buildings now enclose a quadrangle of
grass, ringed by sidewalks and crisscrossed with lights.
Andback to the "warm, fuzzy" goals that were estabSchool of Medicine and Biomedical Sciences Research Building
lished at the outset- serve as a front door to the medical
school complex.
Laboratory units ................................................. 60
"The materials that we chose were very quiet, so we
attempted to give a lot of interest to the pattern and shapes"
Equipment rooms ........ ............... .... .............. ...... 12
of the exterior, Wong says. "We chose the glass to be very
harmonious with the brick. We attempted to create a diaUtility rooms ............................................... .. ...... 12
logue. The most prominent windows are for the office areas,
and there are areas of large glass, such as the big vertical
element at the corner of the building near the front entrance.
Common work rooms .. .......... ......... .... ...... .. ......... 6
"In everything we did on the exterior, there was a very
conscious effort to create an articulation of the exterior
Darkrooms .. ... ... ... ...... .. .. .... ... ........ .... ... .... .. .... .. ... 12
walls. Shadow and play give this building a sense of scale. We
chose to use as many of the given elements in as artistic a way
Environmental chambers ................................. .. . 18
as possible.
"We tried to create a sense of balance and harmony with
Conference areas ............ ........... ................. .. ......... 6
the other elements that were pre-existing. The CFS complex
had a fairly warm tone, and we attempted to borrow from
that. The dental school had a palette that was a little more
Offices ................................ .......... .. ..................... 60
rich. We tried to create a sense of harmony that would bridge
all the elements that were there and at the same time create
Laboratory space ....... .............. 110,000 square feet
an identity distinctive to the medical school."
An identity - but as yet, no name.
Building .. .................... ... .. ... ... . 210,000 square feet
"We do hope to name it," Bruce Holm says. "There have
been some ideas. There are lots of people you can name
About $54 million, funded by the State
COST
buildings after. "
For the research building's new tenants, at least, the name
University of ew Yorl? Construction Fund
is excitement.

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�Rror~anization of scientists

anrf rlinicians 111lomises
srner~islic results
t

��"The building is more than just a building," Holm said.
"It's really meant to be a catalyst to put into effect an overall
plan that's part of our mission for the next decade or two. It's
allowed us to bring together people who wouldn't otherwise
have come together. I'm very excited about it."
Much of the school's research is performed at the hospitals of the Graduate Medical Dental Education Consortium
of Buffalo, where many of the medical school's faculty both
teach and practice. That hospital-based research will continue , Holm said ; the new research centers, or "affinity
groups" as they are known, each comprising from 10 to 30
people, will do their work in the new building, and in renovated dry-lab space in the Cary-Farber-Sherman complex.
"What we're moving are highly productive, highly thematic research groups, " he said. "They've actually in large
measure self-formed. We left it to the
investigators to find their own affinities,
and some people are members of more
than one group. "
It's hoped that the new alignments
will help continue a decade-long trend
that has greatly strengthened the medical school's position among major medical research universities.
Holm estimated that during the 199394 academic year, the school's faculty
members brought in $30 million in grant
money- excluding the approximately
200 faculty on the staff of Roswell Park
Cancer Institute. Add in the grants to
those Roswell Park researchers , and the
figure climbs to $58 million.
"It's dramatically on the increase ,"
Holm said. "My guess is that, 10 years
ago , we were lucky if we were talking
$10 million.
"We've recruited new faculty members and initiated some new programs,
and it's taken off in a big way. It's been a
concerted effort to build up the research program in the
school of medicine," he added.
A thriving research program has two major benefits.
Foremost, of course, it advances the frontiers of scientific
knowledge and medical treatment. But it also gets the medical school's name out in front of the national scientific
audience, making it much easier to attract the top-quality
investigators and teachers who , in turn, create the best
education for future physicians.
Holm points out a third advantage, one that directly
benefits medical students: "We have a variety of programs for
the medical students centered around these research activities, that in fact teach them how to think.
"When they go out into a world of medicine which is
constantly changing, their education will be continuing for
the next 30 or 40 years.
"They need to be able to look at the literature and to be

able to critically read journal articles and determine what is
the best type of treatment for their patient. Having a strong
research program means that we're imparting that creative
thinking quality. "
A comprehensive survey of research at the medical school
would fill a book. But a quick overview gives a snapshot of
the variety of projects being undertaken , both in basic
medical science and in the clinical application of that science.
Here, then , are some highlights of the medical school's
research activity:
Thomas]. Langan , M.D., associate professor of neurology
and pediatrics and an attending neurologist at The Children's
Hospital of Buffalo , coordinates an affinity group in Neurosciences focusing on the provocative idea that the brain, long
thought to be unable to repair itself,
"doesn't simply age and deteriorate but
has a potential for a positive kind of
change. "
The eight members of the group , he
says, are looking into such areas as how
the visual system changes over time, and
how it can regenerate and repair itself.
Research on the cellular level, into such
mechanisms as ion channels and protein secretions, seeks to discover how
the nervous system changes with time
and how clinicians might manipulate
that. One member, a neurosurgeon , is
investigating transplantation strategies
to address conditions such as Parkinson's
disease.
Langan , whose own research concentrates on the plentiful brain cells
called astrocytes , says formation of the
new affinity groups can only help researchers' collaborations.
"We don't talk enough to each other,"
he said of investigators in general. "The
kind of exchange that most people find most productive is
running into each other in the hall and talking things over.
This will enhance that kind of day-to-day collaboration. "
And Langan, who sees young patients with such brain
insults as cerebral palsy, mental retardation and epilepsy,
welcomes the alliances between basic scientists and clinicians.
"Scientific illumination has to come before any attempt at
treatment," he said. "The draw really was to try to understand some of these terrible brain syndromes, and by understanding them better, find out how to change things. "
Robert Hard , Ph.D. , and his colleagues in the Imaging Center
are accomplishing what was unimaginable before the invention of the microchip. Using powerful new technologies of
video microscopy and computer methodology, they study
tissues , cells- even individual molecules within cells.
They accomplish that by using fluorescent markers to

The new alignments

continue adecade-long
trend that has greatly

strengthened the medical
school's position among
major medical research
universities.

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�Bruce A. Holm. Ph.D.
Associate Dean for
Research and
Graduate Studies

Associate Professor of
Neurology and Pediatrics

�John A. Krasney. Ph.D.
Professor of Physiology

target molecules , attaching them covalently in a way that
doesn't disturb the molecules' function , and then following
them at low-light levels.
The group has 16 members from five teaching departments.
"There are people doing the same kinds of research in
these different departments , and these interdisciplinary programs afford an opportunity for them to interact on a more
formal basis than usually occurs," Hard , associate professor
of anatomical sciences, said.
Other sophisticated technology that the Imaging Center
has in place or hopes to install: confocal microscopy , which
enables the researcher to collect information in three dimensions and make 3-D computer models of cells; atomic force
micro copy, so incredibly sensitive that it can measure forces
between molecules; and laser tweezers , which use a laser
beam to move parts of an individual cell around, even slicing
chromosomes off a mitotic spindle.
"The idea is to get everybody on a common Ooor and use
(the Imaging Center) as a resource for the whole medical
school, as well as promote more interactions on applying this
technology to a variety of medical problems," Hard said.
The Cardiopulmonary Center was initiated in 1990 to build on
the medical school's diverse faculty interests in cardiovascular and pulmonary physiology. About 40 investigators are
working in three major subgroups- cardiovascular medicine, pulmonary medicine and developmental biology.

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"Over the years here at Buffalo, one of the great research
strengths of this university has been in cardiovascular and
pulmonary research ," saidjohn A. Krasney, Ph.D., professor
of physiology and liaison for the group. "The problem has
been that we've been geographically separated. Many of the
labs are at Erie County Medical Center and at other hospitals ,
and some of us who are doing basic science are here on the
Main Street campus."
ow, bringing together the affinity group can result in
much more convenient and frequent interaction. "We're
interested in the physiologic mechanisms that regulate and
control the circulation in various situations," Krasney said.
He gives as examples the problems of coronary artery disease, pulmonary disease , high blood pressure and changes in
circulation that occur at birth. Cardiopulmonary Center
investigators also are exploring how nutrients are carried in
the blood to the body's organs and cells, and how that
nutrient transfer is accomplished.
One high-profile project under way is a ASA-supported
study of how elevated carbon dioxide affects circulation to
the brain. ln both the U.S. space shuttle and the Russian Mir
space station, carbon dioxide levels have approached a very
high 3 percent.
"This can lead to problems in the ability of the astronauts
and the cosmonauts to function, " Krasney said. One part of
this study is being done in Cologne, Germany, in collaboration with scientists of that nation.

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�----

--

-

Robert Hard. Ph.D.
Associate Professor of
Anatomy and Cell Biology

At the Center for Microbial Pathogenesis, researchers are looking
at parasitic, bacterial and viral pathogens involving such
projects as vaccine delivery systems and vaccine development, host-parasite interactions, the body's immune response to bacteria and how various viruses work in cells.
One development being tested: a vac- .----.-------cine to prevent middle-ear infections
in infants.
The researchers point to four prevalent infectious diseases that have arisen
in the past 15 years - AIDS, Lyme
disease, Legionnaire's disease and toxic
shock syndrome - as evidence of
how much work remains to be done.
This center in january announced
that it has received a $1 million grant
from the Lucille P. Markey Charitable
Trust, which will be used primarily to
hire additional researchers. Medical
school officials hope that funds from
this leading grant-giving organization
for fundamental biological and medical research will contribute to the
school's ability to attract new investigators.
In announcing the award , UB President William R.
Greiner said, "This important award indicates the Markey
Trust's confidence in, and support for , UB's work in

crucial areas of biomedical research. It will be the critical
ingredient that supports major progress in the study of
infectious disease."
'The Markey Trust's award will play a crucial role in the
university's ability to seek matching funds for infectious
disease research from other private and
public foundations and agencies," said
john aughton, M.D., vice president
for clinical affairs and dean of the medical school.
john Hay, Ph.D., professor and
chair of the medical school's microbiology department and a principal investigator for the Markey award, noted,
"This award will allow a marked expansion of the center's important disease investigations. It also will give a
substantial boost to the national and
international reputation of the center
and UB. "
Holm , also a principal investigator
for the award, says the center developed from a collaboration initiated in
1981 by three scientists in different departments in the
medical school. The center now includes 15 senior investigators , as well as support staff, and input from five
departments.

The pmgmms for the
medical students

centered around the
school's research

activities, in fact teach
them how to think.

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�Other research efforts involve basic scientists and clinician scientists:
The Metabolic Regulation Group studies how cells regulate their
metabolism by hormones and other mechanisms. Investigators are looking at how cells use copper, the regulation of
insulin secretion, the mechanisms governing obesity and the
use of surfactants in treating lung disease in newborns.
In the Molecular Mechanisms of Cell Regulation Center, researchers
are investigating how proteins work in regulating cell processes and metabolic pathways, in addition to their function
in such diseases as cancer, endocrine disorders and skin
diseases. An overall goal of the group is to understand how
these proteins affect expression of the genetic code in the
body's development and aging, as well as its pathologies.
Discovering the physical configuration of cells and their
component molecules is the focus of the Structural Biology Center.
Its investigators use X-ray crystallography and nuclear magnetic resonance imaging to discern molecular structures,
including those of proteins, D A and RNA, carbohydrate
and membranes.
The Toxicology Research Center is in its seventh year of
operation. Its focuses include developing in vitro methods
of studying the body's reaction to foreign substances, in
contrast to toxicology's traditional in vivo animal-based
research. For example, in a study funded by the ational
Institute of Environmental Health Sciences, researchers

are seeking to develop biological markers that would
indicate exposure to a particular substance. "The goal,"
says james Olson, M.D. , associate professor of pharmacology and liaison for the group, "is a simple test, like a
blood test, to determine whether someone has been exposed to a substance or is susceptible to damage from
exposure. " The investigators, he said, are looking for
changes in molecules or cells, such as levels of enzymes
or messenger R A.
The group's other main focus, Olson says, is measuring
levels of the chemicals themselves in the blood. For example, toxicologists have monitored the health of people
who live along the Great Lakes and eat fish that may expose
them to such contaminants as PCBs, dioxin and myrex.
Excessive exposure may lead to reproductive and developmental problems.
Initiatives in outcomes research and primary care constitute another major area of medical school investigation.
Several new projects of the Rural Health Initiative study health
policy and practice in the nation's rural areas. One, funded
by the federal Office of Rural Health Policy, looks at the
impact of managed care on rural communities throughout
the United States, and the impact nurse practitioners have
had on health care in rural areas. Another explores how the
spread of AIDS has affected rural health care systems. A
companion study looks at why immunization rates vary

John Hay. Ph.D.
Professor and chair of
Microbiology

�~~~-

~-

--

--

~

James Olson. M.D.
Associate Professor of
Pharmacology

fighting coronary artery disease , osteoporosis and endometrial cancer; studying how a low-fat diet affects risk of
cardiovascular disease and breast and colo rectal cancer; and
investigating whether calcium and vitamin D supplements
reduce the risk of osteoporosis, colorectal cancer, high
blood pressure and breast cancer.
Initiatives in Rehabilitation Medicine include the Uniform
Data System, which is being developed into one of the
largest databases in the world on issues in medicine , pediatrics and gynecology.
"They're able to provide different subsets of this data to
different people who need it for generating policy decisions,
in the clinical management of patients, or to do outcomes
research ," says Holm.
Again , a brief survey only hits the highlights of the wideranging and growing research program at the medical school.
Holm , for one, expects research to remain a strong part of
the school's activity.
"Our IH funding is growing, and it's as high as it's ever
been," he said. "Realistically we're not going to be able to
keep up this level of growth in the current (political)
climate. But even if we were to plateau at the current level,
I would not be unhappy.
"I think it's a very exciting time ."

greatly from county to county.
Thomas Rosenthal, M.D. , chair of family medicine, says a
new Department of Health grant will enable researchers to
study how rural primary care physicians use the government's
medical guidelines in treating the fast-growing illness of
congestive heart failure. "We'll look how closely physicians
in rural ew York State follow those guidelines, and if not,
why not; and what kinds of things could be done to increase
the use of those guidelines, if that's appropriate ," Rosenthal
said.
That's not specifically a rural issue, he acknowledged.
"But there are differences in how medicine is organized in
rural communities and in urban areas. We've developed a
reputation for being able to look at these things in a rural
environment. "
Another initiative in outcomes research and primary care
involve UB as one of 16 vanguard clinical centers nationwide that are part of the $635 million Women's Health
Initiative , the largest clinical trial ever undertaken in the
United States.
Investigators are recruiting as many as 3,500 women from
Western New York, and the study will include both clinical
and observational components. Among the investigations:
testing how effective hormone replacement therapy is in

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FDA chief David Kessler, M.D, J.D,
delivers 1995 Harrington Lecture
SAYS AGENCY HAS A RESPONSIBILITY TO DETERMINE
THE POTENTIAL BENEFITS NEW DRUGS CAN BRING AS
WELL AS THE POTENTIAL HARM THEY CAN BRING

esponding to recent public criticisms that his agency moves too
slowly in approving new drugs ,
Food and Drug Administration
Commissioner David Kessler ,
M.D. , ].D. , told a standing-room
only crowd at the medical school that
the FDA has dramatically increased the
access that patients with life-threatening
diseases have to promising new drugs.
Kessler delivered the D.W.
Harrington Lecture February 9. He said
the FDA has sped up the approval process for new drugs and increased patients' accessibility to new drugs that are
still in the clinical stages of testing.
Kessler, who was appointed by President George Bush in 1990, said the
AIDS epidemic changed the way the
FDA handles the approval process for

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new drugs offering potential treatments
for patients with terminal diseases. He
said in today's world , it is important for
these patients to have the right to take a
chance on a new drug when seemingly
all other treatments have failed.
"Experimental sources of therapy,
such as new drugs , represent a rare
source of hope for those people with
conditions that have seemed to outsmart medical science," Kessler said. He
said he realizes the FDA must address
the unique problems facing those patients who have nothing to lose by trying experimental treatments. "In urgent
cases where people are dying and no
effective therapy exists, something more
is required of the FDA," he added.
The FDA has come under sharp criticism recently from conservative groups

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that believe the government over-regulates the pharmaceutical industry and
hurts its ability to compete globally, as
well as causes unnecessary deaths to
people who could be helped by therapies awaiting FDA approval. Full-page
ads in national newspapers trumpet, "If
a murderer kills you, it's homicide. If
the FDA kills you , it's just being cautious. "
But Kessler points to widespread
misconceptions about the length of time
it takes for the FDA to approve a new
drug. "For most drugs , the average approval length is l3 months, " he said,
"not seven years or 10 years like most
people think. "
Sometimes the agency moves even
quicker. Kessler, a graduate of Harvard
Medical School and the University of
Chicago Law School, said that in the
past few years four new drugs- most
notably the potential AIDS treatment,
DDI - received approval in less then
seven months. Kessler said this kind of
fast-track approval is one of the best
ways the FDA can address the needs of
patients afflicted with life-threatening
diseases.
In 1992, he noted, the FDA also began granting conditional approval to
certain drugs before final confirmation
of direct evidence of their effectiveness
is made. Drug manufacturers now can

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· · · · · · · · · · · · · · · · · · · · · · · · · · · · · · · · · · · · · · · · · · · · · · · · · · · · · · · · · · · · · · · · · · · · · · · · · · · · · · · · · · · · · · · ·a
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"The riskiest thing we can do is to not take risks. Especially since patients have said that they are willing to take the risks."

said it is "not enough for the FDA just to
get new potential therapies to people
who need them. " lt is also its responsibility to "get answers" about the potential benefits a drug may bring as well as
the potential harm it can cause.
"The challenge," he said, "is to strike
the right balance between access and
answers.
"One day we're going to make a mistake ," he said. "But the riskiest thing we
can do is to not take risks. Especially
since patients have said that they are
willing to take the risks."
The magnitude of these risks depends
on the precision of the FDA approval
process, which Kessler said "is only as
good as the scientific research on which
it is based. " Participation in the clinical
trials phase of that research, he said, was
closed to the most seriously ill patients
- ironically, those who might benefit
most from the experimental drugs being
tested - until 1987 when the FDA
opened the doors for tens of thousands
of seriously ill people, mostly AIDS patients, to receive drugs free of charge
while the drugs are in clinical trials
Kessler said the FDA had to realize
that while diseases such as AIDS "have
no geographical boundaries, access to
cuLLing-edge medical technology often
does. "
ln 1992, this program was expanded

"Experimental
sources of therapy,
such as new drugs,
represent a rare
source of hope for
those people with
conditions that have
seemed to outsmart
medical science."
apply for conditional approval if they
prove a drug is "reasonably likely" to
successfully treat a disease.
Kessler said drugs receiving conditional approval are still held to the same
standards as drugs receiving full approval and that manufacturers must
conduct post-marketing studies to ensure efficacy. But, he said, "the less time
a drug is in clinical trials, the less we will
know about it and the more risks we will
take when we make it available." Kessler

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to include even more patients.
"Today, drugs that show promise are
being made available to patients before
they have received final approval from
the FDA and before they are marketed
to the public," said Kessler.
The D.W. Harrington Lecture Series
was established in 1896 by Devillo White
Harrington, an 1861 graduate of the UB
medical school and a professor of genitourinary and venereal diseases from 1886
to 1905.
BY

CHRIS

SHEA

Hershey appointed to Veterans
Affairs Neurology AdrtsoryGroup
inda A. Hershey, M.D., Ph.D., associate professor of neurology and
chief of neurology service at the
Buffalo VA Medical Center, has
been appointed to membership on
the Department of Veterans Affairs eurology Advisory Group.
The appointment was made by john
Booss, M.D., VA's director of neurology
service for the 171-medical center system.
The 11-member advisory group, composed of both VA and non-VA physicians,
will serve as a policy advisory body for the
nation's largest health care system.

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Hauptman-Woodward Institute
honors Kanski and Tomasi

Nolan granted mastership in
Amencan College of Physicians

he Hauptman-Woodward Medical
Research Institute, Inc. (HWl)
honored two local physicians during its Fourth Annual Awards Luncheon held in january.
james R. Kanski, M.D., clinical
associate professor of medicine and a
practicing physician with The Buffalo
Medical Group, received the Helen
Woodward Rivas
Award for service to
HWl.
Thomas
B.
Tomasi, M.D., Ph.D.,
president and chief
executive officer of
Roswell Park Cancer
Institute, received
James Kanski, M.D.
the George F. Koepf,
M.D. Award for his contributions to the
advancement of biomedical research.
The awards were instituted in 1992
to honor the founders of HWl.
Kanski received his medical degree
in 1960 from UB's School of Medicine
and Biomedical Sciences. A member of
the HWI board of directors since 1975,
he served as vice president and chairman of the nominating committee for
most of his tenure.
Kanski
stepped
down from the board
in january after 20
years of service. He
has also served as
chief of the endocrine clinic of The
Buffalo General HosThomas B. Tomasi, M.D.
pital.
Tomasi received his medical degree
from the University of Vermont Medical
School and his Ph.D. from Rockefeller
University. The author of more than
300 publications and abstracts, he also
serves as chairman of Roswell's department of molecular medicine.

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ames Nolan, M.D., professor and
chair of medicine, has been granted
mastership in the American College of Physicians by that body's
board of regents.
Masterships are given to fellows
who have made distinguished contributions to the medical profession because
of personal character, positions of honor
and inOuence, eminence in practice or
in medical research or other attainments
in science or the art of medicine.
olan received the award at the
College's 76th Annual Session in Atlanta this month.

Naughton receives honorary
degree from Kosin University
ohn aughton, M.D., vice president for clinical affairs and dean of
the School of Medicine and Biomedical Sciences, received an honorary degree of doctor of medicine
from the Kosin University in Pusan,
Korea, last month.
Naughton, dean of the school since
1975, is an acknowledged authority in
the areas of exerci e physiology, exercise testing , cardiac rehabilitation,
graduate medical education and
regionalization of health care. His professional training is in internal medicine, cardiology and psychosomatic
medicine.
He holds fellowship status in the
American College of Physicians, the
American College of Cardiology and the
American College of Sports Medicine.
He has authored or co-authored over
120 peer-reviewed articles and two textbooks. He formerly directed the rehabilitation center at the University of
Illinois School of Medicine in Chicago,

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the Division of Rehabilitation Research
and Training Center at the George Washington University Medical Center, Washington, D.C., and the ational Exercise
and Heart Disease Project.

Hui elected to fellowship by
American Physical Society
ek Wen Hui, Ph.D., research professor in the department of biophysics at Roswell Park Cancer Institute, as been elected a fellow by
the American Physical Society.
Each year the society's council
elects members whose distinguished
efforts have advanced physical science
or its applications. Election to fellowship is limited to no more than half of
one percent of the membership, or one
in 200.
Hui, a specialist in electron optics, was
honored for his "innovative application of
electron diffraction and other physical
methods to elucidate membrane and liquid crystal structures, phase transition
and membrane diffuse mechanisms."

Sarkin named to chair pediatric
association'seducation panel
ichard Sarkin, M.D., clinical associate professor of pediatrics and
attending physician at The
Children's Hospital ofBuffalo, has
been elected to the position of
chair of the Ambulatory Pediatric
Association's Special Interest Group on
Medical Student Education.
As chair, Sarkin is responsible for
making recommendations on curricular structure and teaching methodologies for medical students across the country during their pediatric rotations.
Sarkin is also a member of the executive committee of the council.

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· · · · · · · · · · · · · · · · · · · · · · ·· · · · · · · · · · · · · · · · · · · · · · · · · · · · · · · · · · · · · · · · · · · · · · · · · · · · · · · · · · · · · · · · o

March Foundation'ssupport to
school approaches $1 million

loan fund to ensure help is available for
students when unanticipated needs arise.

lara March graduated from the University of Buffalo School of Medicine in 1907 and never treated a
single patient. But she helped thousands of sick and injured people
through her generous support of
education for generations of physicians.
At her death in 1967, the assets from
March's estate were used to create a
foundation for the medical school's benefit. Each year for nearly a quarter of a
century, the Clara March Foundation
has provided significant support for the
school's students. Last year the foundation presented another generous gift of
$65,000 for loans and scholarships, brining its total support to nearly $1 million.
The foundation's annual gifts to the
medical school provide 20 to 39 scholarships a year, in amounts from $1 ,000 to
$10,000. A portion of the foundation's
support is also set aside in an emergency

illS elects RPCI researcher Joel
Huberman,Ph.D, to rank of fellow
oel Huberman, Ph.D., rese~rch professor at Roswell Park Cancer Institute and one of the nation's leading
experts on D A replication, has
been elected to the rank of fellow by
the American Association for the
Advancement of Science.
Huberman, a cancer research scientist
in the department of
cellular and molecular
biology at
Roswell , was honored by the AAAS for
his "pioneering studies of D A replication, particularly for
his discovery and characterization of

eukaryotic DNA replications origins. "
Each year the AAAS elects members
whose "efforts on behalf of the advancement of science or its applications are
scientifically or socially distinguished. "

Brodsky first woman officer of
pediatric otolaryngology society
inda S. Brodsy, M.D. , UB associate
professor of otolaryngology and
director of the pediatric
otolaryngology department at The
Children's Hospital of Buffalo, has
been elected treasurer of the American Society ofPediatric Otolaryngology.
She is the first woman officer elected
to the organization. She has also been
elected to the board of directors of the
Society for Ear, ose and Throat Advances in Children, as well as the American Academy of Pediatrics, Section on
Otolaryngology and Bronchoesophagology.

At a reception for Clara March Foundation staff, trustees and recipients: from left, medical student and scholarship recipient, Aisha Prim; Foundation
accountant M. Jane Dickman, C.P.A.; Foundation trustee Carmella DiPasquale; vice president of clinical affairs and dean of The School of Medicine and
Biomedical Sciences John Naughton, M.D.; Foundation trustee Frank W. Warhus and his wife; and medical student and scholarship recipient James Murray Jr.
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�One of the many
gardens at the Buffalo
City Hospital. Circa
1930.

EtM~ built ~m ~e~
t~
peoJ~e mf its commmmity
MEDICAL CENTER'S ROOTS DATE BACK TO AN
OLD SCHOOL BUILDING REQUISITIONED IN

1909

TO DEAL WITH SCARLET FEVER EPIDEMIC

rie County Medical Center had its roots in two Buffalo hospitals and an old
, school building requisitioned in 1909 as a temporary contagious disease
hospital by the then-commissioner of health Ernest Wende, M.D., and the
mayor of the City of Buffalo,]. N. Adam.

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THEN

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In 1918, the new Buffalo City Hospital and opened in 1951. It was later named
opened its doors; it was one of only 12 in the Donald C. O'Connor Memorial Wing
the country that accepted all diseases for in honor of the hospital's third superintreatment. Later that year, the Erie County tendent.
The last building added to the hosAlmshouse and Infirmary, located on the
pital was the new School
present site of the Univer84
for crippled children,
sity at Buffalo's Main Street
renamed
the ComprehenCampus, burned to the
sive
Care
Center for Chilground. Patients from the
dren, which opened in
Almshouse were moved to
1971.
the new Buffalo City HospiGround was broken
tal - abruptly and unexfor
the
present Erie County
pectedly turning the new
Medical
Center on Octotuberculosis hospital into a
ber
27,
1971,
culminating
public general hospital.
10 years of meetings, disThe original buildings of
cussions, consultations
the Buffalo City Hospital
and planning.
housed administrative ofThe new hospital
fices and patient beds. In
on Grider Street
building
1922, more patient care
became
a
reality
because
of the untiring
space and the original urses Home were
efforts of a group of civic-minded citiopened.
One year later, communicable dis- zens led by then-county executive B.
john Tutuska; Mrs.
ease space was opened. And
Mildred Campbell, chairin 1924, the Crippled
woman of the Meyer HosChildren's School84, a day
pital Advisory Board; and
school for children with the
Dr.
Kenneth Eckert, presiresidual handicaps of polio
dent
of the Comprehenand other crippling diseases,
sive
Health Planning
was opened.
Council of Western ew
The name of the Buffalo
York.
City Hospital was changed
Designed by Gordon
to the Edward J. Meyer MeFriesen Associates of
morial Hospital in April
Washington, D.C., the
1939 in honor of Edward].
new Erie County Medical
Meyer, M.D., a prominent Above, Alpine Sun Lamps
Center was one of the most
were used in the treatment
Buffalo surgeon who served
of
tuberculosis,
rickets,
modern and inefficient,
as president of its board of
scurvy
and
some
skin
novative hospital buildmanagers for 20 years. A
diseases. Below,
ings in the country when
member of the University of
fluoroscopy. Both pictures
it opened its doors on july
Buffalo School ofMedicine's
circa 1930 from "Views of
9,
1978.
class of 1891, Meyer also
the Buffalo City Hospital."
Today, it serves as one
served as an instructor in
of the medical school's afsurgery and adjunct profesfiliated teaching and resor of clinical surgery.
Editor's note: Special thanks
to Ed Leisner of Erie County
In 1946, control of the
search sites, as well as the
Medical (enter's medica/library
Edward]. Meyer Memorial
area's designated Level I
for his help in compiling this
Hospital was transferred
Trauma Center, burn
article.
from the City of Buffalo to
treatment center, AIDS
the County of Erie.
unit and a host of other
The last addition to the
acute care and ambulatory
Grider Street hospital was
services available to the
built for psychiatric patients
community.

n the winter of 1909, Buffalo was gripped by an epidemic of scarlet fever. With
some 3,000 reponed cases
and no contagious disease
hospital facilities in the area,
Wende and Adam, on February 19, 1909, urgently converted an
abandoned school building on the corner ofBroadway and Spring streets into a
temporary contagious disease hospital.
The only other public hospital facility in
Buffalo at the time was the Municipal
Hospital at 770 East Ferry Street. Frequently referred to as the "pest house," it
was operated by the Buffalo Health Department exclusively for the care of smallpox patients.
In 1910, the city saw an alarming
increase in the incidence of tuberculosis.
That year, 561 tuberculosis deaths were
reported, prompting the city fathers to
plan a hospital for the treatment of tuberculosis patients. The 70-acre West Farm
on Grider Street was purchased for
$200,000 as the site of the new Buffalo
City Hospital. It would cost another $3
million to build and equip it.
In 1913, due to the rapid decline in the
incidence of smallpox as a result of the
gradual acceptance of the smallpox vaccine, Municipal Hospital was converted
into a tuberculosis hospital to be used
until the new hospital was erected on the
Grider Street site.
The high rate of tuberculosis in the
city and the total lack of facilities to care
for children with the disease attracted
the attention of Edward H. Butler, Sr., the
founder and publisher of the Buffalo
Evening ews. As a result of Butler's efforts, a temporary tent hospital, large
enough to accommodate 50 children,
was erected on the Municipal Hospital
grounds adjoining the original building.
With the onset of a typically frigid Buffalo winter, the children were moved
inside. Before the Buffalo City Hospital
was completed, three separate units were
added to the Municipal Hospital for the
care of patients suffering from venereal
diseases, alcoholism and psychiatric problems.

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Spoonful

of

Humor©

Stu

Silverstein,

( BUT NOT QUITE AS MODEST AS SOME

ithin the next few months we
will once again have to face the
ugly specter of the health care
debate in the " ew Congress."
As a physician, l feel it is my duty
to give my congressman (whoever he is) my thoughts on the matter. l
plan on making my own proposals.
Here in California we witnessed the
passing of Prop 187, "the illegal alien
initiative. " lam currently collecting signatures in anticipation of getting the
"Silverstein" initiative on the ballot:
anyone in California who tries to start
up another HMO or managed care company automatically qualifies as an illegal alien.
Recycling is important in California,
so my health care package will respect
this by taking the 1,000-page plan that
Clinton came up with and cuLLing it into
16th's to use as prescription pads. We
can use half of them to prescribe sedatives for ewt Gingrich. (You know, if
Elvis were alive today he'd be 60, and
probably look something like ewt.)
The guy is going wild , on the first day
Congress was in session he climbed into
Tom Foley's seat screaming like some
kind of a rodeo clown running away
from Richard Simmons.
ewt is calling for us to sign on with
his "contract with America. " Look ,
Democrat or Republican, you have to
wonder about a guy who is willing to
solve all your problems if you sign a
contract with him. l suggest we shave
his head and see if he's got three 6s
tattooed on his skull. That might even
explain the election results.
"Network marketing" is big these
days, especially among physicians try-

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OF NEWT'S !)

ing to augment their incomes to pay malpractice premiums. l
think we should apply the concept to
health care reform.
For instance, if you
are a patient having
a spinal tap, you've
still got your hands
free , so you'd have the
option of doing a spinal
tap on the person
in the next bed.
Then you can bill
him for your
services, thus
reducing
your health
care costs.
He works on
the person next to him
and so on. The last person out just files for
bankruptcy and even..-.--=~
tually nobody pays,
and (almost)
body gets
hurt.
My plan
would inc I u de

thing from warehouses. The
Clinton plan requires that
states set up large consumer groups called
health alliances to
collect premiums
and bargain with
health care providers.
All companies with
5 ,000 emplo yees or
fewer would have to buy
coverage through an aliiLook, why don't they
just hand over the job to WalMart? Pretty soon everyone
will be employed by
them anyway .

We could call it "The Slice
Club." You walk in to
the shop, pick up a bag
of Almond Joys, leg
warmers and pick a
urologist off the
shelf to fine-tune
your prostate.
We could
even
have a
driv ethrough
out p a tientwindow ....
that's where Ross Perot gets his hair cut
and look what it's done for him.

...

just to make sure it gets approved in the
House and Senate, the definition of
therapy will include chiropractic adjustments at clinics that charge $7 a
drink.
These days everyone is buying everyh

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M.D.

Slll Si /rcrstci11, p•csidc111 of Sta11dup Mcdici11c
Scmi11ars of Sa11 Fra11cisco, lect ures 11aliollwidc
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Stockton Kimball talk highlights annual symposium
MEDICAL A L UMNI ASSOC IATION ' S 1995 SPR I NG CLINICAL DAY PRESENTATIONS
FOCUS ON "THE PHYSIC IAN -

hysicians are men and women of
commitment, conscience and skill
who face some of society's most
challenging problems on a daily
basis. Indeed , life and death issues
are at the heart of medical practice ,
and so even private domestic relationships become part of a history and physical.
The School ofMedicine and Biomedical Science's 58th Annual Spring Clinical Day, Saturday, April 29 , at the Buffalo Marriott, will address a variety of
subjects encountered by physicians and
other professionals concerned with the
field of child sexual abuse, neglect, adolescent trauma and violence to the elderly.
The conference, entitled , "The Physician- Healing the Abuse in Our F amily ," is intended to increase professional
skills in prevention , recognition , assessment and treatment of all forms of maltreatment in the family system.
The pres en lations will emphasize the
awareness physicians need to recognize
abuse in their patients and to encourage
their roles as advocates for their patients.
Specific approaches to these issues
will be offered by the experts who have
been carefully selected to speak at this
year's program , designed to touch both
the heart and the mind.
The program has been designated for
up to four hours of Category I Credit
toward the Physician's Recognition
Award of the American Medical Association and four prescribed hours by the
American Academy of Family Physicians.

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HEALING THE ABUSE I N OUR FAMILY"

Faculty of this year's program inIntroduction
clude:
john
F. Coyne, M.D. '85
"Amy" - Outreach Coordinator,
Program
Chairman
PACT Clinic ofThe Children's Hospital
of Buffalo
Richard David Krugman, M.D. Landmarks in the Field of Child Abuse
Dean and Professor of Pediatrics, School Stephen Lazoritz , M.D.
of Medicine, University of Colorado ,
Denver, Colorado
Stephen Lazoritz, M.D.- Medical Post Traumatic Stress in Abused
Director , Child Advocacy Center , Children and Adolescents
Children's Hospital of Wisconsin ; As- Susan V. McLeer, M.D .
sistant Professor of Pediatrics, Section
Head , Medical College of Wisconsin ,
Milwaukee, Wisconsin
HIV: The Physician Can Make the
Susan V. McLeer, M.D.- Professor Difference
and Chairman, Department of Psychia- "A1ny"
try, School of Medicine and Biomedical
Sciences, University at Buffalo
Kathleen G. Pharris, M.S.W. Coffee Break - Exhibit Reviews
Director of Senior Day Center and Family Focus Program, Catholic Charities
of Buffalo
The Physician's Role as the Child
Robert M. Reece , M.D.- Director,
Advocate
Institute for Professional Education ,
Robert M. Reece , M.D.
Massachusetts Society for the Prevention of Cruelty to Children, Boston,
Massachusetts
The Tragedy That May Be Overlooked
The agenda follows :
Kathleen G. Pharris, M.S.W.
Registration
Business Meeting
Welcoming Remarks
Russell W. Besette, M.D. '76
President, Medical Alumni Association
john aughton, M.D.
Vice President for Clinical Affairs
Dean, School of Medicin e and Biomedical
Sciences

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Annual Medical Alumni Luncheon and
Stockton Kimball Memorial Lecture
Child Abuse Prevention: Is It Too Little
Too Late? Or Is It the Light at the End
of the Tunnel?
Richard D. Krugman , M.D.
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Alumna dedicated her life to helping othe~
LISA BECHTEL '86 , PRACTICED WHAT SHE SAW AS THE IDEAL OF MEDICINE:
A PATH OF SACRIFICE TO HELP THOSE WHO NEEDED IT MOST

he lesson of Lisa Bechtel, M.D.
'86, is one of humility.
She died May 10, 1994, in Las
Vegas, evada, where she made
her home, conducted a private
practice, managed a clinic and
was in the process of raising three children.
She and I palled around in medschool.
What drew us together was what we saw
as the ideal of medicine: a path of sacrifice to help those who needed it most.
She went to Pittsburgh to do her
family practice residency at Shadyside
Hospital and I went to Rochester's Highland Hospital to do mine. Pressures of
residency ate up time for both of us, and
we drifted apart, losing touch. I married,
adopted a child, and- the old storygot pregnant and had a second child.
The majority of my family medical practice centered on inner city clinics in
Buffalo.
What I didn't know at the time was
that in significant ways, Lisa's life was
paralleling mine. She found a spouse,
they adopted three children, and true to
our ideals, she worked where people
needed her most. From a alive American reservation in northern evada, she
moved back to her home town, Las Vegas.
By this time-Ilearned later, almost
too late - her life and work had begun
a new phase. This phase as much as
anything defined the ideal of self-sacrifice - going beyond anything we had
talked over so ardently back in med
school, and the truth is, surpassing anything l had imagined for her or myself.
Lisa was lesbian, so she was well

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ACADEMIC H ALTH
PROFESSIO ALS

I
Insuring care for those who care

Subscriber
Owned • Organized • Governed
PHYSICIANS • DE TISTS
HEALTH PROFESSIONALS
NURSES • RESIDENTS

acquainted with the gay subculture, by
then ravaged and haunted by the AIDS
epidemic. She began working with AIDS
patients, partly because of her innate
sympathies, but largely because they
weren't on top of
doctors' lists. In
fact, the Las Vegas AIDS clinic
was unable to
attract a medical
director - low
pay, very long
hours, draining
work, emotionally costly. The
position was offered to Lisa. She
took it. At once
she became an
indispensable
figure of hope,
charity, comfort
and support, as
well as medical
attention.
And it went
further. Pediatricians asked her
if she would see
HIV -positive
children who
weren't getting
the attention they needed. Way too few
physicians knew how to treat them. She
agreed.
Her partner, Ann, a nurse practitioner who also worked at the AIDS clinic,
was well aware of the need. Together
they took another step. First they
adopted an HIV-exposed baby, naming
her Mariah. A year later she tested negative. Then they took in another unwanted baby - HIV-exposed in utero ,
plus various teratogens such as crack
and alcohol. They not only kept her
alive, but she thrived with them , and
continues to as of this writing. Then a
third baby, ate, was adopted. He was a

year old last December. His HIV results
are still inconclusive.
Then, the wretched misstep occurred.
Cleaning up in the clinic, depositing
syringes in the dirty needle box, Lisa
nicked herself. She
filed a report and
promptly forgot
about it.
That was in
Aprill993.
Six weeks
later she developed a raging fever and viral syndrome. Her T cells
fell so rapidly that
within a few
months she was
diagnosed with
full-blown AIDS.
She grew too
weak to carry on
in medicine. In a
little more than a
year, she died.
But not before the gay community rallied
around her.
By this time,
we had renewed
our contact after
so many years, finding our friendship
intact, reaffirming our beliefs. At a
large, astonishing benefit in Las Vegas, the kind of celebration that snubs
death , Lisa was honored . I attended
and I don't think I've seen such an
outpouring of gratitude and sympathy
for one person.
All good physicians dream of making
a difference. Lisa Bechtel made a difference- a very, very big difference. Her
example continues to make a difference
in me, an object lesson that in this one
profession whatever we think is enough,
is never enough.

All good physicians

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Academic Health Professionals
Insurance Association is a subscriber
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licensed by the Insurance Department
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ofthe Association are determined by a
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Transfers arranged \vithout loss.
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very big difference.

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Four receive 1994 Lifetime Career
Achievement Awards
ifetime Career A hievement
Awards were presented to four
alumni last year.
Andrew A. Gage , M.D ., '76,
William R. Kinkel , M.D ., '5 4 ,
James F. Mohn, M.D. , '44 and

Max A. Schneider , M.D., ' 49 ,
received the Medical Alumni
Association's 1994 Lifetime Career
Achievement Awards at last year 's
pring Clinical Day and Reunion
Weekend celebration.
The awards are presented in
recognition of conspicuous and
outstanding career achievement.

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Andrew A. Gage, M.D.

William R. Kinkel, M.D.

James F. Mohn, M.D.

~

Max A. Schneider, M.D.

\.hi

OFFICH

uestionnaires for the special Sesquicentennial edition
of the alumni directory have been sent out by the
Harris Publishing Company.
Please be sure to complete and return your directory

Call UB

questionnaire before the deadline indicated.

cro to

nqu~re'

• Apple • IBM • Dell • Compaq •
Panasonic • Hewlett Packard • TI
• Sony • Software • Supplies
• Accessories • Audio
• Hands-on Workshops

Prior to the publication date, the Harris Company will
contact you after the data have been compiled to verify the
information in your listing.

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became board certified in critiof
Johns Island, South Carolina,
writes that after interning at
Buffalo's Deaconess Hospital and
HAROLD J . ELLIOTT '38 ,

cal care medicine in addition to
internal medicine and pulmonary diseases. He is director of
respiratory service and associ-

orthern Westchester Hospital,
he practiced medicine for six
years in the mountains of Kentucky, eight years at orthern

ate director of the sleep disor-

igeria Mission Hospital, 18
years in southeast Minnesota and

and living in Chicago.

for the past 23 years in Johns
Island, Charleston County,
South Carolina, in a poor
people's clinic in a church building. At age 80, he's still active

ders lab - still actively practicing medicine, skiing and !ly fishing. His son, George, is married

board certified examiner of the
American Board of Forensic Examiners.
'65 ,

of

STANLEY L. OLINICK '40 ,

Winter Park, Florida, was certified in forensic psychiatry by

points out a crowning irony of

The American Board of Psychia-

his career. In what may be his
final (or nearly so) year of private practice of psychoanalysis,

try and eurology after successfully completing the first exam
given in the field last October.
He has previous certification

he has been included in the second edition of "Best Doctors in
America." He continues to write
papers for psychoanalytic journals, teach and enjoy his family,
tennis, music and reading.
LEONARD

WOLIN

'41 ,

of

was appointed president and

to professor of radiology at
Northwestern University Medical School. He is director of

chief executive officer of the Long

neuroradiology and a member of

Island Jewish Medical Center.

the strategic planning committee
-AS R. His

is a

senior partner at Kenmore Pedi-

was

atric Associates, P.C.; medical
director for ight Call, an afterhours telephone triage service for

elected president of the Chi-

of

JAN

ARTHUR SCHWARTZ

Westwood, Massachusetts, was
elected president of the Massachusetts Academy of Dermatol-

'75,

is a pediatric anesthesiolo-

ROBERT A . KUWIK '72 ,

of

Johnson City, Tennessee, left
private practice to accept a position as assistant professor of psychiatry at East Tennessee State
University Quillen College of
Medicine. His oldest son, Brian,
is a Fulbright scholar in
Cameroon, Africa, until October
1995; middle son, ick, is a junior at Florida State University.

psychiatry since 1992 and is certified by the American Society of
Addiction Medicine and the
American Board of Quality Assurance and Utilization Review.

Rhode Island. He wrote that he
and his wife were expecting their

Marrow and Blood Stem Cell

Severin-Salzman.

third child, a son, in January 1995.

JOHN R . AND E R SON '67,

RICHARD

ofDepew, ewYork, was named
medical director of the Brothers

Sparks,

PFOERTNER

'60, of Boise, Idaho, recently

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BARNETT SALZMAN '65 ,

of Mercy ursing and Rehabilitation Center in Clarence, New

p

ARTHUR C . SGALIA '73 ,

of

Wrentham, Massachusetts, was
named chief of internal medicine
at Rehabilitation Hospital of

S.

LEE '74 ,

of

evada, was appointed

chief of neurology and director
of neurosciences of orthern
Nevada Medical Center.

0

Society.

12; and Meredith, 7.

of
Bowling Green, Kentucky, was
appointed medical director of
the adult unit of Riverdell Psychiatric Hospital as well as a new
member of the American Board
of Forensic Examiners. He recently married Stacy Jean

B.

cal

can Academy of Pediatrics.

he's now "retired" but keeps up
with his computer and the latest
news, including the very latest
from the Los Angeles Times, about
his son, MAURICE J . WOLIN
'84 , of Westlake Village, California, and his work for the
Westlake Medical Center's Bone

GEORGE

cago RadiologiThey have two children: Gabrielle,

ogy. He has two daughters.

with added qualifications in geriatric psychiatry and addiction

recently

New York Chapter 1 of the Ameri-

ALLEN BERLINGER '71 ,

Amherst, New York, writes that

Transplant Center.

K. Fernbach,

physicians; and vice president of

three days a week.
KOLIN

DAVID R. OANTZKER '67 ,

ROGER A . FORDEN '70,

'65 , of Newton, Connecticut,
recently became a diplomate and

S.

ERIC J . RUSSELL '74 , of
Chicago, Illinois, was promoted

wife, Dr. Sandra

AUGUST J . D 'ALESSANDRO

IRVING

York, where he has been a staff
physician for two years.

5

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gist at the Geisinger Clinic, in
Danville, Pennsylvania. She recently spent three months as a
visiting professor of pediatric anesthesiology at the department
of anesthesia of Soroka Medical
Center, Ben Gurian University
of the

egev, Beer-Sheva, Israel.

DENNIS WHITEHEAD '75 ,

chief of emergency services for
Dickinson County Memorial
Hospital in Iron Mountain,
Michigan, is serving a two-year
term as speaker of the council of
the American College of Emergency Physicians. He recently
became the 36th person (and
second physician) to climb the
highest point in each of the 50
states. He writes that he's looking forward to his 20-year class
reunion this spring.
B E NNETT VOG E LMAN '78 ,

was appointed to the University of
Wisconsin Teaching Academy and
promoted to professor in 1994.

g

9

9

5

�~ -··· ····· ··· ········· ······· ····· ·· ········· ······· ···· ······························ · ····

1

9

8

KATHERINE
DECARIA '80 ,

s

0

VINCENT

JASNOSZ -

of Murrysville,

Pennsylvania , is a staff pathqlogist at Allegheny General Hospital in Pittsburgh. She has two
children: Daniel, 5; and Anna, 4.
of

LOIS M . MCNALLY '82 ,

ew York City, was appointed
director of medical student education for the ophthalmology
department of the ew York Eye
and Ear Infirmary where she

JOSEPH

1

FASA -

'86 , and his wife,

NE LL O

Donna, announce the birth of
their second child, Diana Christine, on December 20, 1994.
JESSIE JEAN -RUSH '86 ,

9

9

s

0

of

Cleveland Heights, Ohio, write

ship at Naval Hospital in Jacksonville, Florida. He is now serv-

that joe is currently a fourth-year

ing as a general medical officer

E T resident at the Cleveland
Clinic. Mary completed her pe-

on board the amphibious dock

BONAFEDE

'91 ,

MARY CAPPUCCINO '91 ,

Tucson, Arizona, is a general
pediatrician and major in the
U.S. Air Force at Davis MonthanAir Force Base. She has three

diatrics residency at Children's

landing ship the U.S.S. Gunston
Hall, currently deployed to the

Hospital of Philadelphia in 1994

Mediterranean Sea.

and is currently doing a pediatric
infectious disease fellowship at

beautiful children: Kira, 10;

Rainbow Babies Hospital in

Eddie Jr., 8; and Kesha, 6.

OBITUARIES
BENNIE MECKLIN '35 ,

practiced family medicine in the
Thousand

Islands

T I NA MARIE GARDNER '87 ,

practices ocular oncology and

of Malone,

attended by many classmates. A

Watertown,

ophthalmic pathology.

''I'm a family physician working

great time was had by all.

46 years, died

MARC KOBLICK '84 ,

and his

wife, Helene, proudly announce
the birth of their third child,
EricJordan, born June 21, 1994.

ern New York. We are teaching
.P. students

in our practice. My son jake is 4

of

outdoorsman, with a strong in-

Westlake Village, California, is

terest in plants and trees and

co-director of the Westlake

gardening. I'm expecting my sec-

Medical Center's Bone Marrow

ond child next month. "

of Stamford, Connecticut, joined

ROBERT

HESS

a private practice group of six

'37 , died

ovember 8, 1994 in

pediatricians there. She writes

Oceanside, California. He was
an assistant plant physician and

and sends news about "lots of

surgeon at Bethlehem Steel in

babies

Lackawanna,

to

our

classmates:

a baby girl, Ilana;

has

INGRID

ew York, for 38

years before his retirement in
1972.

has a baby girl, Natalie;

PATRICK E . RYAN , JR . '87 ,

CRUSE

is an associate professor at the

COLLEEN

of Bal-

University Hospital in Syracuse,

ZITTEL

timore, Maryland, is director of

KINGA

the EMG Laboratory at Johns

ew York, where he's been an
in
physician
attending

girl, Alexa.

Hopkins Bayview Medical Cen-

cardiothoracic surgery since last

but a new house desperately in

ter and an assistant professor of

july. His \vife Denise, he writes,

need of a new roof and paint job,

neurology at Johns Hopkins

is staying at home for now, tend-

so lots to keep Joe and me busy."

School of Medicine. Her son

ing to their children: Sean, 5;

Alexander was born March 6,

Erin, 3; and Kieran james, 18

1994. She writes that classmates

months.

ROB I N CONWIT '85 ,

MEHNERT

that she "is really enjoying it!"

ELISSA JAFFE BOOKER

and Blood Stem Cell Transplant
Center.

ovember 14,

JENNIFER F . HENKIND '91 ,

years old and is quite an
MAURICE J . WOLIN '84 ,

and

ew York, area for

1994, at age 83.

for the Mohawk Tribe in Northmedical, P.A. and

who

Cleveland. They were married on
November 19, 1994 at a ceremony

ew York, writes,

com-

and

JOE

of

PAUL D . SEEMAN '93 ,

pleted his family practice intern-

AND

GREG

have a boy, George; and
TIBOLD has a baby
o babies for me yet,

MAT THEW J . PHILLIPS '91 ,

died july 14, 1992.
CHARLES TANNER

~3 ,

a

Buffalo cardiovascular surgeon
and former president of Mercy
Hospital, died December 7, 1994
after a long illness.
WALTER A . OLZEWSKI '54 ,

ew York, and his

assistant professor of neurology

wife, Toula, announce the birth

and clinical associate professor

of

of their second son, Michael

of anatomy and cell biology, died

Ventura, California, has been

Nicholas, born December 12,

February 23, 1994.

and

practicing internal medicine

1994. He joins his brother ,

are

there since August 1992. She

james, who turns 2 on April 7.

expecting second babies this

and her husband Thomas Alfano,

AMY

MILLER

O 'DONNE LL

had her third son, Michael , in
February
RE ICHARD

of Snyder,

VINCENT J . PARLANTE '42 ,

1994;

A L I S ON

PETERSO N

SARAH MURRAY WH ITE

YASMIN

PANAHY

'89 ,

STEPHEN J . KIMATIAN '92 ,

who were married in December

spring.

ANDRE

MIDGETTE

' 79 ,

drowned in Brazil in june 1994
of Navarre, Florida, writes that

1991, welcomed a son born September 15, 1994.

while on vacation with his wife
and daughter.

he is a [light surgeon for the U.S.
Air Force in Special Operations
at Hurlburt field , Florida.

a

a

0

p

h

5

c

a

n

5

p

n

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9

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                    <text>State University of New York at Buffalo School of Medicine and Biomedical Sciences, Autumn 1995

FROM DARI&lt;NESS TO DAYLIGHT
UB's Traumatic Brain Injury Rehabilitation System repairs broken lives

�BUFFALO PH Y S I CIAN

Volume 29,

umber 4

ASSOCI ATE VI C E
PRESIDENT FOR
UN IVERSITY SE RVICES

Dr. Carole Smith Petro
DIRECTOR OF
PUBLICATIONS

Timothy j. Conroy
ED ITOR

Nanette Tramont, R.N.
ART DIRECTOR

Alan J Kegler
ASSOCIATE ART DIRECTOR

Dav1d R1ley
E DITO RIAL MANAGER

judson Mead
PRODUCTION MANAGER

Ann Raszmann Brown

Dear Alumni and Friends,

T

his issue of Buffalo Physician describes the Traumatic Brain Injury Rehabilitation
System that has proven so successful in Buffalo. The story provides yet another
example of how collaborative efforts among institutions can facilitate patient care,
enhance the education of health professionals and promote meaningful clinical
opportunities that can utilize the resources of other institutions to
positive advantage. As importantly, the system has ensured that
patients can be treated in Western New York rather than be transferred to service delivery sites in other parts of New York, or in other
states. The latter actually provides an economic savings for the
citizens of Western New York since such services are more costly, as
well as inconvenient, when patients with head injury are treated in
other states.
We congratulate the medical, hospital and other leadership that
worked to make this system a reality and a success.
Sincerely,

STATE UNIVERSITY OF
NEW YORK AT BUFFALO
SCHOOL OF MEDICINE
AND BIOMEDICAL
SCIENCES

Dr. john Naughton
Vice PreSt den! for Cluucal Affairs

j ohn Naughton, M.D.
Vice President for Clinical Affairs
Dean, School of Medicine and Biomedical Sciences

Dean
EDITORIAL BOARD

Dr. john A. Richert, Chairman
Dr. Marttn Brecher
Dr. Harold Brody
Dr. R1chard L. Collins
Dr. Alanj. Dnnnan
Dr. James Kanski

Dr. Barbara Marjeroni
Dr.
Dr.
Dr.
Dr.
Dr.
Dr.

Elizabeth Olmsted
Charles Paganelli
Margaret W. Paroski
Thomas Raab
Stephen Spauldtng
Bradley T. Truax

TEACH ING HOSPITALS AND
LIAISONS

The Buffalo General Hospital
Michael Shaw
Buffalo VA Medical Center

Arlene Kelly
The Children's Hospital of Buffalo
Ene County Medical Center
Mercy Hospital
M1llard ftllmore Hosp1tals

Frank Sava
Roswell Park Cancer Institute
Sisters of Chanty Hosp1tal
Dennis McCarthy
©The State Umversity of New York
at Buffalo

Buffalo PhySician IS publtshed
quarterly by the State University of
New York at Buffalo School of
Medicine and Bwmed1cal Sciences
and the Office of Publications. It IS
sent, free of charge, toalumm, faculty ,
students, residents and friends. The
staff reserves the right to ed1t all copy
and submissions accepted ror
publicatiOn.
Address questions, comments and
subm1ssions to: Editor, Buffalo
Physietatt, State Universny of New
York at Buffalo , Universuy
Publications, 136 Crofts Hall, Buffalo ,
New York 14260

Send address 1hanges Ia:

Buffalo
Physiciatt, 147 CFS Addition, 3435
Matn Street, Buffalo, New York 14 214

Dear Fellow Alumni,

T

his year is Oying by, and we are rapidly approaching the beginning of our Sesquicentennial. Numerous events have been planned to celebrate the 150th anniversary of
our medical school, and we hope you will be able to join us for some or all of the
festivities.
As you know, this past year the Medical Alumni Association purchased furnishings
for the medical student lounge. The students were most appreciative, and acknowledged
our efforts with a reception and commemorative plaque. Our Alumni
Association was also honored with representation on the newly
formed Dean's Advisory Council, which held its first meeting October 25-26, 1995. The Council has broad geographic representation,
and alumni traveled from as far as California to attend the meeting.
The group toured the new Biomedical Research Building, which is a
spectacular addition to our medical campus. Dr. Beth Maher informs
me that plans for Spring Clinical Day are shaping up nicely. Dr.
Sherwin Nuland, author of How We Die, will be the Stockton Kimball
lecturer. His topic will be "Death, the Doctor and Hope." He wrote
to Dr. Maher, "Your school is a place I have long admired, and the feeling is always
enhanced by my visits."
We hope you will enhance Spring Clinical Day with your presence, and I'll look
forward to seeing you there on May ll, 1996.
Enjoy,

~~

W.

?~~J Ml)

Ma rga ret W. Paroski, M. D. '80
President, Medical Alumni Association

�V

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9

9

N

4

9

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II Resear(h
II Hospital News
GME Maelstrom e UB's graduate medical educaII The
tion consortium girds itself for fundamental
changes in financial support system.

m

Putting Ba(k the Pie(es

e

UB's Traumatic Brain
Injury Rehabilitation System repairs broken lives.

IIJ Medi(al S(hool
EiJ Then and Now

m
m

ASpoonful of Humor

Flying the friendly
skies. Page 21.

Alumni

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Classnotes

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UB biologists build better mouse
model for Duchenne MD research

mark absence of dystrophin and increased mast cell activity characteristic
of the disease, it doesn't exhibit the
progressive weakness that is a symptom
of Duchenne muscular dystrophy. He
said the mice exhibit a degree of muscle
weakness and degeneration , but only
after they are physically stressed by running on treadmills for periods of time or
are injected with chemicals that induce
mast cell activity.
"We wanted a model that would express the full symptoms
of the human disease ,"
Hudecki said. He and his
colleagues bred mice
with the dystrophin deficiency and the exaggerated activity of mast
cells throughout the
body. The findings show
that not only does
d ys trop hin-deficien t
muscle contain a greater
number of mast cells, but
the muscle tissue also
appears to be hypersensitive to mast cell products, he added.

niversity at Buffalo biologists have
developed a new mouse model of
Duchenne muscular dystrophy
that may more accurately simulate the progression of the disease
than current models.
The research, which should also provide an enhanced understanding of the

-

formed about pain management, and
that this lack of knowledge interfered
with the nurses' ability to provide adequate treatment.
The study, which appeared in the May
issue of the journal of Pain and Symptom
Management, points to a problem with
nursing and medical school curricula,
according to lead author Kathleen G.
Wallace, Ph.D., assistant professor of
nursing and postdoctoral nurse fellow
at Buffalo's Department of Veterans Affairs Medical Center.
"Nurses and physicians are not taught
enough about pain management," she
said. "Schools have not made the commitment to teach it. ln the meantime,
the knowledge base of pain management is exploding. "
The pilot study involved 108 staff
nurses selected from a random sample
of hospitals in Georgia, Louisiana, ew
York and Washington , D.C. Since staff
nurses are usually the first on the scene
when a patient is in pain, their sensitivity to, and skill in dealing with, pain
problems is critical for effective pain
management, Wallace said .
Study participants were asked to rate
themselves in several areas related to
pain management-educational preparation, practice skills and knowledge of
legal, financial, political and ethical issues - and to rate the importance of
each area. They also listed the three
most important problems of pain management in their facility.
Undermedication surfaced as the most
significant problem of pain management.
This finding is a step forward , Wallace
said, because previous reports have
shown nurses and physicians generally
did not believe patients were being
undermedicated.
The researchers found that most of
the nurses interviewed thought their
pain management skills were adequate,
even though other studies repeatedly
had found the opposite to be true.

B Y ELLEN GOLDBAUM

The new mouse could provide enhanced understanding of the disease.
role mast cells play in the disease, was
published in the july issue of the journal
of Neurological Sciences.
Michael S. Hudecki, Ph.D. , research
associate professor ofbiological sciences,
ndermedication is the most signifiis the senior author. Coauthors are jocant problem of pain management
seph A. Granchelli, postdoctoral fellow ,
in hospitals, one of the first studies
and Catherine M. Pollina, research asto investigate how nurses assess
sociate. The work was funded by the
their knowledge of pain and their
Muscular Dystrophy Association.
skill in alleviating it has shown.
"There has not been a good model for
The pilot study, conducted by UniDuchenne muscular dystrophy ," versity at Buffalo nursing researchHudecki said. "This specially bred mouse ers , also revealed that nurses think
gives us a very good handle on studying they are adequately informed about
the Duchenne disease. "
managing pain, despite research
Hudecki explained that while the pre- showing they aren' t.
vailing animal model, a mouse deficient
But the nurses interviewed believed it
in dystrophin, closely simulates the hall- was the physicians who were ill-in-

Nurses see undermedication as
major pain management problem

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Rural AIDS cases increasing three Improved survival seen with new
times faster than in urban areas head and neck cancer treatment
IDS cases in rural areas appear to be
increasing at a rate three times faster
than in metropolitan areas, where
health care facilities are better
equipped to deal with the problem.
Rural AIDS cases increased 9.4
percent from 1991 to 1992 - the last
period for which comparable statistics
are available- compared with 3.1 percent in major metropolitan areas , according to a review of scientific literature focusing on rural HIV/AIDS conducted by UB's ew York Rural Health
Research Center.
The review also found that unlike the
typical urban AIDS patient, likely to be
homosexual males, rural AIDS patients
are more likely to be heterosexual females.
"In terms of both total cases and research, rural AIDS remains dwarfed by the
urban epidemic," said Robin Graham,
Ph.D. , senior research scientist at the center and lead author of the study. "But our
literature review indicates that AIDS is a
serious rural problem, with growing numbers of patients requiring services from illequipped local health care systems."
The studies reviewed revealed several distinct characteristics of the rural epidemic:
&lt;§&gt; The rate of increase of AIDS cases in
proportion to the population is much
greater in rural areas.
©&gt; Rural AIDS is distributed unevenly,
with 30 percent of cases concentrated in
the South Atlantic states.
©&gt; Rates are particularly high among
black women , adolescents , ative
Americans and migrant workers.
©&gt; A substantial portion of rural HlV
patients have migrated to metropolitan
areas , returning home to family exhibiting advanced cases of the disease.
&lt;§&gt; Intravenous drug use and heterosexual contact are becoming significant
modes of transmission of rural HlV.
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chemotherapy shrunk it to 1/2 centimeter, we still took it out as if it were two
centimeters," Lore states. Significantly,
all the patients in the study were evaluated and treated by Lore , who resected
the tumors to .5 to 2 centimeters beyond
the point at which they had been marked
by tattoos following diagrams , anatomical stamps and photographs.

new treatment regimen for head
and neck cancer developed at the
Head and eck Center at Sisters of
Charity Hospital could hold promise for some of the estimated
30,000 Americans who are diagnosed with the disease yearly.
The new regimen, which combines
preoperative chemotherapy with an innovative surgical technique , was pioesearchers and clinicians from
neered by John M. Lore, M.D. , medical
several UB departments are orgadirector of the center. Lore presented
nizing a Group for Advanced Vihis research , scheduled for publication
sion
Research to bring together
in the American journal of Surgery, at
people working in the field to
the annual meeting of the Society of
collaborate on research , coordiHead and eck Surgeons last May.
Lore demonstrated a five-year sur- nate funding efforts, share resources
vival rate of 76 percent in one group of and enhance teaching.
93 patients with advanced squamous
William Coles, M.D. , professor and
cell carcinoma of the head and neck he chair of ophthalmology, is the group's
treated over 15 years with one of two executive director. Malcolm Slaughter,
preoperative chemotherapy protocols. Ph.D., associate professor of biophysical
Previous survival rates , as demonstrated sciences and ophthalmology, has been
by the ational Cancer Institute's 1987 named director of basic research , with
Head and eck Contracts Program, av- James Reidy , M.D. , assistant professor of
eraged 35 percent.
ophthalmology, serving as director of
The Head and eck Center's dramatic clinical research.
76 percent survival rate was seen in the 40
Researchers from the UB Departments
patients who received cisplatin and 5-0uo- of Clinical Laboratory Science, Anatomy,
rouracil preoperatively. Another 48 who Pediatrics, Biochemistry and Social and
received preoperative
Preventive Medicine have alcisplatin and bleomycin
ready affiliated with the group.
posted a five-year surCurrent members are conducting funded research 1n- - vival rate of 43 percent.
(Five patients were
diabetic
retinopathy,
noncompliant.)
retinopathy of prematurity,
The crux of Lore's
age-related macular degenregimen is the strict aderation, corneal inOammaherence to preoperative
tion, neuro-ophthalmology
chemotherapy planand outcomes of surgical proning of ablative
cedures in the developmenuncompromised surtally disabled.
gery regardless of a fa- Angiogram displaying abnormal
The group is organizing a
vorable response to the retinal vascular pattern.
research conference for 1996.
chemotherapy. "If the tumor was 2 cen- Periodic grand rounds and continuing edutimeters prior to chemotherapy, and the cation seminars are also planned.

UB researchers,clinicians form
advanced vision research group

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�Buffalo General and Buffalo
Columbus finalize merger plans
merger plan involving Buffalo
Columbus Hospital; its parent organization, Buffalo Healthcare
Corp.; and The Buffalo General
Hospital has been finalized, hospital officials announced recently.
The merger agreement, according to
BHC board chair Vincent]. Muffoletto ,
represents "a major step toward providing vastly expanded services to our medically underserved community. "
The Honorable joseph S. Mattina,
chair of the board at Buffalo Columbus Hospital, observed that board
members had "agonized" over
the future of the institu-

john E. Friedlander, Buffalo General's
president and CEO , praised judge
Mattina, Muffoletto , Garcia and members of the BC/BHC boards for exhibiting "extraordinary vision and determination.
"Columbus represents a critical service provider for the community and
specific patient populations, including
the indigent, people who are HIV-positive , substance abusers, the
chronically ill
and people

noting that Buffalo Columbus has a work
force of 290 and Waterfront 200. "With
approximately 500 staff, the campus will
be a major employer on the WestSide."

Sisters Hospital fights domestic
~olence with Crtsis Services
he Safe Passage Program, Sisters
of Charity Hospital's domestic
violence program, has implemented an innovative working
relationship with Crisis Services,
a nonprofit human services
agency that specializes in crisis response.
The pilot collaborative effort between Sisters and Crisis Services
will provide for the training of
both crisis advocates from
the agency and hospital
staff, beginning with social
workers , to serve as victim
advocates.
"We are training staff who
will respond to victims' needs on
a 24-hour basis," said Kathleen
Slammon, M.S.W. , coordinator
of the Safe Passage Program.
Approximately 50 volunteers
from Crisis Services' Advocate Program previously experienced in
working with rape victims will receive
additional training specific to domestic
violence, including the dynamics of abusive relationships, standards of care for
victims and community resources. The
volunteers will supplement the services
provided by Sisters Hospital social workers, who will also receive training specific to domestic violence.
"The intent of this collaborative effort
is to provide victims with consistent and
comprehensive care," Slammon noted.
Physicians, nurses and other hospital
staff will be trained in domestic violence
identification and intervention following the first phase of instruction for
social workers and advocates.

f

tion for several years.
"This agreement with
Buffalo General will allow ~
us to mamtam our presence
on the Lower West Side, provide better services than ever
before, proceed with construction of a diagnostic and
treatment center, and preserve as many jobs at this
facility as humanly possible,"
Mattina explained.
Earlier this year, the hospitals and
BHC announced that discussions were
under way to develop a merger plan in
an effort to preserve, enhance and expand health care services for the city's
West Side. Under the plan, the current
Buffalo Columbus facility will be replaced
with a diagnostic and treatment center.
"Throughout the negotiations, the
good of the community always came
first ," remarked Andres Garcia , president and chief executive officer of Buffalo Columbus Hospital. "Our foremost
responsibility is to the people of the
Lower West Side, and our goal is to
make this work so that they will have a
community health care facility they can
be proud of. "

?)

with special needs ," Friedlander said.
According to Friedlander, the merger
plans include "the extension of new and
existing services, while moving ahead
with the process of developing a health
care campus, including a diagnostic and
treatment center at the site. "
The 160-bed Waterfront Health Care
Center, a residential health care facility
operated by General Care Corp. , parent
organization ofBuffalo General , has also
been mentioned in the plans to create a
health care campus.
"Currently, we are exploring ways in
which Waterfront and Buffalo Columbus
can work together to create a West Side
health care campus," Friedlander said,

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"The entire hospital staff will be required to receive training. The extent of
that training will depend on a person's
position," Slammon added.
The Safe Passage Program recently
received a $10,000 Legislative Local
Initiative Award from the New York
State Department of Social Services.
Funds from the award will be used to
further develop the domestic violence
program in the areas of intervention,
advocacy and counseling services.

Medical staff reappointments
announced at Mercy Hospital
hree UB physicians have been reappointed to key medical staff positions at Mercy Hospital of Buffalo.
Saleela Suresh, M.D. , clinical
assistant professor of rehabilitation medicine , has been reappointed as chair of rehabilitation medicine, a post she has held since 1979. She
earned her bachelor's degree from the
University of Calcutta, India , and her
medical degree from the R. G. Kar Medical College in Calcutta. She served rotating internships in Calcutta and at the
D.C. General Hospital in Washington,
D.C. Suresh holds membership in the
American Academy of Physical Medicine and Rehabilitation, the Medical Society of the County of Erie, the Medical
Society of the State of New York and the
American Association ofElectromyography and Electrodiagnosis.
Noel Chiantella, M.D. , clinical assistant professor of radiology, has been
reappointed as chair of Mercy's radiology department. He earned his bachelor's
degree from Mount St. Mary's College in
Emmitsburg, Md., and his medical degree from the University of Maryland
Hospital. He served as a lieutenant, general medical officer, in the U.S. avy.
John Fanelli, M.D. , has been appointed chief ofMercy's division of family practice, department of internal
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medicine. He earned his bachelor's degree from Niagara University and was
an Army ROTC Distinguished Military
Graduate. Fanelli earned his medical
degree from UB , and served a rotating
internship at the Ireland Army Hospital
in Fort Knox , Ky.

CHOB wins approval for acute
pediatric inpatient rehab unit
he ew York State Department of
Health has approved The Children's
Hospital of Buffalo's certificate of
need to develop an acute pediatric
inpatient rehabilitation unit.
"There are no certified inpatient
beds for acute pediatric rehabilitation in
the Western ew York area, " said Joseph A. Ruffolo, president and CEO of
Children's Hospital. "The acute needs
of these patients are being met usually
via transfer to acute inpatient rehab
units outside of Western ew York and
often outside of New York State. The
gap in health care delivery results in
fragmented and duplicative care for patients who require intensive rehabilitation services. Patient relocation forces
temporary relocation for the family,
which creates inconveniences and increased cost and stress," Ruffolo said.
The inpatient rehabilitation unit will
provide a multidisciplinary team approach for the treatment of brain dysfunction, traumatic spinal cord dysfunction, stroke, amputation of limbs, congenital deformities , neurological conditions , arthritis and other conditions.
The treatment team will consist of the
following medical disciplines: developmental pediatrics, education, occupational and physical therapy, social work,
psychology, nutrition, rehabilitation
nursing and speech therapy.
"With a strong outpatient rehabilitation unit in place and numerous inpatient
services providing referrals and direct clinical expertise, Children's Hospital demon-

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strates a strong commitment to provide a
comprehensive continuum of care for this
special population. A dedicated rehabilitation inpatient unit will ensure focus on
functional outcome, so as to return each
patient to the most independent setting
possible," Ruffulo added.
The Robert Warner Rehabilitation
Center is the outpatient rehabilitation
component of Children's Hospital.

Grant named chief of pulmonary
and critical care at VA center
rydon Grant , M.D., has been
named chief of pulmonary and
critical care medicine at the Buffalo Department of Veterans Affairs Medical Center.
A graduate of Charing Cross
Hospital Medical School, London, Grant
became interested in research during
his residency and became a research fellow at the Royal Postgraduate Medical
School in London. He continued his clinical training at Middlesex Hospital Medical School in London.
ln 1977, Grant
continued his research in pulmonary
gas exchange and
mathematical modeling at the University of California at
San Diego. In 1979,
he joined the faculty

Brydon Grant, M.D.

at the University of
Michigan. He has
been in Buffalo since 1983 as an attending physician at Erie County Medical
Center in the pulmonary and critical
care division, and as director ofECMC's
pulmonary function lab since 1990.
Grant has served on the editorial board
of Respiratory Physiology and the American Review of Respiratory Disease. He
recently completed a term as an associate
editor of the American]oumal of Respiratory and Critical Care Medicine.

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�n interestin_

times
THE ONLY

CERTAINTY FOR

ACADEMIC MEDICINE

IS FUNDAMENTAL

CHANGE
t

portrait photo s by Robert Walion

EVERY ASPECT OF ACADEMIC MEDICINE WILL BE AFFECTED BY THE FlNA CIAL REFORMS BEING
PLANNED FOR THE MEDICARE A D MEDICAID SYSTEMS -

FROM THE NUMBER OF RESIDE CY SPOTS

AVAILABLE TO NEW PHYSICIANS TO THE PRODUCTIVITY OF THE PROFESSORS WHO TEACH THEM .
AT UB A D ITS AFFILIATED TEACHING HOSPITALS , THE MOOD IS

OT HOPEFUL

�by

Andrew Danzo

THE Fl A CIAL U DERPl
Naughton describes the forces at work: the need for costtion are undergoing a fundamental reorganization. Medicontainment and a more rational approach to medical work
care is being cut back and restructured. Medicaid, too.
force policy; political promises of tax cuts; widening accepGrants are getting harder
tance of business notions
and harder to come by.
of productivity. "These
And in ew York, it's
forces are going to collide
anyone's guess what will
here very shortly,"
happen when the system
Naughton predicts, leanthat has regulated hospital
ing forward during a disreimbursements for more
cussion in the wedgethan a decade comes up
shaped office that he will
for renewal in several
soon leave. He suggests a
months.
label: "Call it the GME
"It's all under attack, evmaelstrom. "
ery bit of it," says john
Graduate medical eduaughton, M.D. , UB vice
cation cost $3 billion in
president for clinical afNew York State in 1994.
fairs and dean of the School
About a third of that came
of Medicine and Biomedifrom Medicare hospital recal Sciences.
imbursements, with most
o one is sure exactly
of the remainder from
how it will play out. The
Medicaid and non-governonly certainty is that
ment insurers. The fundthings will be different ,
ing scheme is complex, to
starting with teaching
put it mildly. Medicare rehospitals and rippling outward.
imbursements are driven by costs
Among the hospital members
in base years updated for inOa.JOHN NAUGHTON, M.D.
tion, calculations of overhead atof the Graduate Medical Dental
tributable to education, estimates
Education Consortium of Bufof illness severity among teachfalo, there is talk of "integraing hospital patients and various
tion " and "downsizing. " Fewer
other factors. Reimbursements
residency slots, perhaps. A testfrom Medicaid and other insuring of relationships among coners are determined by the New
sortium members. Pressure on
York Prospective Hospital Reimfaculty to find time for more
bursement Methodology ( YPHRM), which adheres to
clinical service.
some parts of the Medicare formulas .
"The CEOs know what's going on and know that something will have to give, but they are really unsure ," says Paul
The average reimbursement per resident in 1994 ranged
Candino, chief executive officer of Erie County Medical
from more than $200,000 in the ew York metropolitan
Center. "Once we see what the damage is, we'll be positionarea to about $149,000 in Western New York, a differing for redirecting our strategic initiatives. "
ence that at least partly reOects regional variations in
It may all end up producing something that is more
health care costs. With 788 residents and fellows in the
collaborative and attuned to the needs of a reorganized
GMDECB, it is easy to see how changes in GME reimhealth care system, but the transition will not be painless.
bursement could quickly translate into huge losses for

ult' s all under

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affect medical education, but they are preparing for a
individual hospitals. That could be compounded by
major challenge. Asked what's at stake , Candino reother changes in Medicare, which covers nearly half the
plies , "Everything. "
patients in GMDECB institutions, and Medicaid.
One obvious response would be reducing the number of
Meanwhile, growing proportions of publicly and privately insured patients are
residency slots, and some
in managed care. HMO
hospital executives say
that can't be ruled out. "I
penetration among those
with non-government inthink the decisions will
have to be what can we all
surance in the metropoliafford from an educational
tan Buffalo area is now
about 60 percent, accordperspective as well as an
ing to William D. Pike,
operational one," says Ripresident of the Western
chard Braun, vice presiew York Healthcare Asdent for finance and chief
sociation. HMOs in Buffinancial officer of The
falo have generally been
Buffalo General Hospital.
following the prevailing
He says the consortium
reimbursement rates set
might also have to conunder NYPHRM, even
sider consolidating some
though they' re not reprograms, such as interquired to, Pike says. But
nal medicine, which is
the HMOs are beginning
now split into two parts.
to get more aggressive, he
Naughton agrees that
adds , pointing to one
the government must get
plan's recent exclusion of
residencies under control
hospital labs from a contract for
nationally. In the three decades
outpatient work.
since Medicare began, training
P A U L CANCINO
programs and slots have prolifAs YPHRM approaches its
june 30 renewal deadline , all
erated. The knocks on the system are well known: public
bets may be off. It is YPHRM
funds helping to subsidize a surthat controls the bulk of hospiplus of specialists; geographic
tal reimbursement for such
maldistribution encouraged by
"public goods " as graduate
concentration of residencies in
medical education and indigent
a handful of states- New York
care, and the insurance industry is already pushing to be realone has one-sixth of the
leased from the dictates of diagnation's total; far more residents
nosis-related groups , according
than there are new American
to jeannie H. Cross of the
M.D.s , with programs sucking
Healthcare Association of ew
up
young doctors from counn
York State. "We're moving in
tries where they are needed and
the direction of a more marketmedical schools stymied in their
oriented system ," Cross says. "The question is how fast. "
efforts to rebalance the physician work force .
GMDECB officials warn that there are still too
"Obviously, the feds have a big job to do ," aughton
many unknowns to predict exactly how all this will
says. But Buffalo , he quickly adds , is not the place to do it.

uThe CEOs l&lt;now
what's going on
and l&lt;now that
something will
have to give, but they
are _really unsure.

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The GMDECB has been a national model since it adopted a
self-imposed cap on residency slots several years ago. "We
only have a few programs where we could say in the most
rational sense of the word that we have a few excess
residents," Naughton says.
"We'd rather not lose any
because we think the size
is about right. "
Final decisions on residency slots will be inOuenced by a variety of factors. For instance, disincentives for training graduates of foreign medical
schools would be felt in
the consortium, where
about 45 percent of the
slots are filled by international graduates. And even
though the GMDECB is
committed to training half
of its residents in primary
care (it's now at 43 percent), new disincentives for
specialist training could
pose difficulties. "We have a high
surgical component at Buffalo
WILLIAM
General," says Braun, "and as
you start to cut at that, you tear
away at the whole system."
To some degree, hospitals
have already begun weaning
themselves from their reliance
on residents because the programs have been putting greater
emphasis on the educational
component of resident training.
"They're not the slaves that they
had been," says Roseanne C.
Berger, M.D., associate dean for
graduate medical education.
Nevertheless, residents are
still important. "Of our 21 clinical departments, 19 of them
have relationships with graduate medical programs," says
Michael F. Noe, executive vice president and medical

IN

INTERESTING

TIMES

director at Buffalo General. On average, the hospital has
about 150 residents.
"They are very much involved in patient care in the
course of their learning experiences," Noe says. "Once
they reach a certain level
of competency, they directly provide patient
care, particularly in urgent situations. If we did
not have them here in the
hospital, it would be very
difficult to replace them. "
Eventually, fewer residents could also mean
fewer physicians in Western New York , Noe adds.
"As there are fewer people
in training, there will be
fewer individuals familiar
with the area who have
developed a preference for
this area as a place to practice ," he says. "lt could
have an impact on the
availability of people who
go into practice. "
Even if hospitals did cut back
D. P I K E
on residents, it wouldn't solve
their problems. GME reimbursements have become intricately
woven into teaching hospital
budgets, supporting things that
will continue to run up bills
whether or not the residents are
there. The largest part of the
Medicare reimbursement goes
not to direct costs - resident
salaries and benefits range from
about $20,000 to $60,000 in New
York- but to compensate hospitals for the indirect, and somen
what abstract, cost of being a
teaching institution. Based on the ratio of residents and
interns to beds, the indirect component is designed to pay
for such educational costs as the greater number of tests that

aWe have a very lean
machine as far as
health care delivery in
Western New Yorl~.
But we can do better, and
we can do better by
collaborating for
shared services.

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residents tend to order, as well as for things like greater
illness severity among teaching hospital patients. It is
sometimes called an "add-on " to the direct Medicare reimbursement, which is paid according to diagnosis related
group. "Our add-on is gigantic," says ECMC's Candino,
who administers a hospital that is not only a major
academic affiliate, but also
has regional trauma and
burn units and provides
more than $20 million a
year in indigent care.
In New York, hospitals
also receive indirect education reimbursements
from Medicaid and nongovernment insurers
through NYPHRM, which
uses a formula that is similar to Medicare's but adjusted to encourage primary care residencies. The
total indirect component
is about 57 percent of the
$3 billion in GME reimbursements in ew York.
"A lot of it goes to the bottom
line of the hospitals," says James
RICHARD
olan, M.D., director of medicine at ECMC and former chairman of medicine at UB.
Likewise, other reimbursement streams help to indirectly
support the educational mission
of teaching hospitals. GMDECB
officials say they will have to
consider the potential revenue
losses posed by overall changes
in Medicare and Medicaid as they
reassess their teaching activities.
"If education stayed the same
and you cut out $20 million of
other funds , it's hard to say it would have no impact," says
BGH's Braun. "The reality is, if someone cuts your budget
by 10 or l3 percent, you have to react to it. The reaction

IN

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has to be, what programs can we afford? "
Teachers as well as residents are likely to feel the pinch.
"This , of course, comes at a difficult time for faculty ," says Nolan.
"There's been a decrease in state funding and hospital
funding even without these
cuts," he adds. "The hospitals have had to decrease
the support they can give
faculty. And grant support
also has been decreasing."
The combined effects of
various revenue losses "are
going to make it more difficult for full-time faculty to
be financially supported,"
says oe. "In New York
State in particular, our hospitals have operated very
close to the margin. We have
worked in a very heavily
regulated environment for
many years. The impact in
New York State is going to
be significantly greater than
in other states."
Berger sees that leading to
some tough choices for adminisBRAUN
trators and faculty. "I think there
will be an increase in pressure
for clinical activity, which may
take them away more from the
teaching endeavor," she says.
That pressure had been growing already in recent years, and
clinical practice now accounts
forabout$75 million in UB medical school gross income.
Berger says faculty could also
be affected by financial pressure in the practice environn
ment. "As managers begin observing the clinical productivity of faculty more closely, if
there are no allowances for teaching time built in there ,
the standard will be maintained, whatever level is set for

uTh e reality is, if
someone cuts your
budget by 10 or 13
percent, you have to
react. The reaction has to
be, what programs can
_we afford?

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�ACADEMIC

MEDICINE

FINDS

ITSELF

seeing patients," she says. "You're not going to be able to
teach as much while you're seeing patients if you're expected to see more patients."
The coming year will be a crucial one for the GMDECB as
it reacts not only to the federal changes, but to those at the
state level as well. In addition to NYPHRM, New
York's Medicaid managed
care program is still taking
shape, and another round
of state budget cuts looms.
"People are saying that
next year is going to be a
health care Super Bowl in
New York," says Cross, the
Healthcare Association
spokesperson. "NYPHRM
is a playoff game by itself."
The situation could
present some opportunities. For instance, the current system of GME reimbursement does not pay as
much for ambulatory residencies as those in hospitals. Within the GMDECB,
the salaries and benefits of ambulatory residents are covered, but
RO SE ANN E C.
there is no mechanism to pay the
overhead costs. "Until there is
real reform of financing, it's going to be hard to make the changes
that are needed, shifting the locus from the hospital to the ambulatory setting," says Leonard
A. Katz, M.D., director of research
and education programs at Health
Care Plan, which trains two internal medicine residents a year in the primary care: group
practice!HMO track.
The debate over such issues and the ongoing evolution
of health care delivery are likely to put stress on relationships within the GMDECB. With managed care expanding
and a continued push to replace DRGs with negotiated fees ,
hospitals that make teaching a part of their mission will

IN

INTERESTING

TIMES

have trouble competing unless there are adequate mechanisms to compensate them for their higher costs. "You have
people at the consortium table collaborating for graduate
medical education, but at the same time, these collaborators
are competitors for patients," says Pike, of the Western New
York Healthcare Association. "As competition
heats up more and more,
it's hard to sit down and
say, 'let's work together."'
But Pike and others say
they expect the consortium
toweatherthestorm. Ifanything, cooperative efforts
will become more important. "The consortium is a
good example of how the
market is reacting in general," Pike says. "We have a
very lean machine as far as
health care delivery in
Western ew York. But we
can do better, and we can
do better by collaborating
for shared services."
Examples of new partnerships are already emerging as
hospitals form networks that unite
B E R GER, M.D.
a variety of providers and facilities
to offer patients a "continuum of
care" through a single organization. "l think you're going to see
tremendous changes from a standalone hospital system to an integrated delivery systems environment," says Robert V. Stanek, chief
operating officer of Mercy Health
System, the network that now occupies the Mercy Hospital chair at the GMDECB table.
Stanek says the n ew environment will pose challenges
for clinical education .
"Will it strain the mission? Sure it will," he says. "But in
the long term, we're going to continue to provide services
to the community, and as part of that, an educational
mission needs to be maintained. "

uYou' re not going to be
able to teach as much
while you're seeing patients
if you're expected to
see more patients."

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�PUTTING BACK
THE PIECES
US'S TRAUMATIC BRAIN INJURY REHA

I

ITATION

SYSTEM REPAIRS BROKEN LIVES

BY

PHOTOS

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THOMAS

COLLIGNON/JAROSZ

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�--------

-

HE ACCIDE T ITSELF,
Anthony DeLabio doesn't
much remember.
He and a couple of friends were just
fooling around. Too young to drink in
ewYork State, they had walked across
the Rainbow Bridge into Canada and
spent the evening hitting the bars. Then
they had walked back and were hanging
around in the parking lot of the Rainbow Center mall.
"We started horsing around by the
edge of the parking lot," DeLabio,
now 22, says of that fateful September night in 1992. "I
leaned over ... and I fell. The next thing I knew, when I got

percent of traumatic brain injuries are motor-vehicle-related. If you add in pedestrians who are hit by cars, it's closer
to 60 or 70 percent.
"And now, in some cities (though not Buffalo) , gunshot
wounds are coming close to those numbers. "
The medical school's Traumatic Brain Injury Rehabilitation System is a regional consortium that operates at three
levels: ECMC, with its Level I trauma unit and acute-level
rehabilitation; Our Lady of Victory Hospital in South Buffalo, for intermediate-term rehabilitation; and, until recently, the Deaconess Center ofBuffalo General Hospital, for
long-term in-patient rehab.
Labi says she and her colleagues are working with patients
who , had they sustained such injuries 20 years ago , never
would have survived - people with multiple body traumas

Each year, an estimated half million people nationwide
suffer a head injury; a significant proportion of them will
require a course of rehabilitation. The medical school's
Traumatic Brain Injury Rehabilitation System is a regional
consortium that operates at three levels: acute-level, intermediate term and long-term, in-patient.

from crashes, or horrific gunshot wounds. "In the past," she
says, "most of them would have died of complications from
their injuries. Now the emergency medical services are so
much better. With the use of helicopters, patients are getting
to trauma centers much more quickly. And the earlier we can
treat them, the better. "
But reckless drivers and trigger-happy gunmen aren't the
only risks to gray matter. "just about anything can result in
a head injury," Labi says, and she ticks off some examples:
industrial accidents; falls , particularly among older people;
blunt trauma , such as assault with a baseball bat. All can
damage the brain and its delicate neural pathways - and
forever alter the life of the victim.
Anthony DeLabio says of his time on the eighth floor of
ECMC, the head injury rehab unit: "I was totally confused.
I had no idea what was going on. I remember that a couple

my senses back, I was on the rehab floor (of the Erie County
Medical Center)." He had been in a coma for five days before
he opened his eyes.
"The strangest thing was, for a while after the accident I
had these dreams of people falling. ever me, always other
people. And I'd say to them in the dream, 'Don't worry, you
won't remember it."'
DeLabio's story is in some ways typical of the events that
conspire to injure the human brain. Each year, an estimated
half-million people nationwide suffer a head injury; a significant proportion of them will require a course of rehabilitation. Most such patients are young, male - and have been
around alcohol, automobiles or both.
"We live in a fast world," says Maria L. C. Labi, M.D. ,
Ph.D., medical director of the University at Buffalo Traumatic Brain Injury Rehabilitation System. "More than 50

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�of my friends came to see me; other than that, it was just very
confusing.
"But all the people, the doctors and nurses, were very nice
to me. They calmed me down a lot of times, because I felt like
I was caught in a whirlwind. I didn't know why I was in the
hospital. They told me day after day that I fell, but I just
couldn't make the association. I couldn't remember going
out that night. "
But slowly, in the nine-and-a-half weeks he was in the
hospital , and throughout a long course of outpatient rehabilitation, Delabio made the connection. He worked with
physical therapists to learn to walk again. Occupational
therapists helped him relearn "the day-to-day things" showering, getting dressed. Speech therapists helped him
learn to organize his thoughts and taught him strategies to

course. The brain is a delicate and complex instrument, and
damage may forever wipe out a lifetime of accumulated skills
and memories.
Labi, who is an assistant professor in UB medical
school's department of rehabilitation medicine , makes the
distinction between functional and neurologic recovery.
It's not necessarily true , she says , that the central nervous
system can 't regenerate itself: severed nerves sometimes
reconnect through a process called sprouting. "lt's not
always as efficient as it was before ," she says, "but even if
the injured area does not recover , the brain has a lot of
redundancy in it. Other parts can take over the function of
the injured part. "
Failing that, though, the goal is functional recovery. A
patient may be paralyzed, for example, but if he can learn to

PHYSICAL THERAPIST LESLIE MOREDOCK ASSISTS ROGER HOUSER.

improve his memory. They also worked with him to relearn
how to swallow and eat and talk. He worked painfully to
regain coordination in his left hand that was impaired by the
fall. He tried cooking. He passed his driver's test.
Eventually, he got his life back.
"I think that's one of the finest rehab centers around, "
Delabio says now about the Buffalo TBl system. "Besides
being great physicians and therapists, they have an empathy
for the patient. They try to understand what the patient is
going through. That's important."
Delabio's remarkable recovery is the kind of outcome the
rehabilitation teams hope for. It's not always possible, of

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live independently with the help of a wheelchair and maybe
a part-time aide, he has made a functional recovery. "The
system," Labi says, "is intended to make people as functional
as they can be through excellent and cost-effective care.
"It's very rewarding work," she says. "The perception of most
people is that these patients are hopeless, that if they don't come
out of it right away, they're never going to get better. But with
good, appropriate, timely care, they do get better."
Such as:
{i;l The man in his 40s who was hit on the head by an 800pound weight at work. He was back on the job in six months.
{i;l The patient in his late 30s who was run over by a train.

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�"He pretty much broke every bone in his head," Labi notes.
He, too, was recovered well enough to consider returning to
work in six months.
@ The lawyer in his late 20s who was in a car crash in
California- back practicing law in a year-and-a-half.
These cases, Labi says, are different from stroke, the other
assault on the brain, because with trauma, the damage to the
body is generally much more widespread. Patients come
with fractures, blood clots, multiple traumas. Treating them,
and rehabilitating them, means intervening early so their
injuries don't snowball.
"These cases are not typically one little problem you're
working on," says Carolyn Teter, who administers the head
trauma rehabilitation unit at Our Lady of Victory Hospital.
"We're working on many problems at a time."

they hadn't bargained for; they may have trouble accepting
this changed person. One thing is for sure: The family will
never be the same again.
Richard T. Linn, Ph.D., an assistant professor in the
department of rehabilitation medicine and program director
of the UB Traumatic Brain Injury Rehabilitation System, says
accepting what they've lost can be the most difficult part for
head injury patients.
"Most of these folks , when they're on the inpatient unit,
are very confused and still showing quite a bit of disorientation," Linn says. "Many of them are not really ready for
intensive supportive therapy. It's only when they get better
and realize something of what they've lost that it really starts
to sink in."
Linn performs neuropsychological assessments of pa-

"It's veryrewardingwork.The perception of most people
1s that these patients are hopeless, that if they don't
come out of it right away, they're never going to get
better. But with good, appropriate, timely care, they do
get better."
tients with head trauma, trying to establish a baseline level of
functioning and then, later, to assess the patient's progress
six months to a year after the injury.
He also does some psychotherapy with these patients.
"There aren't many psychologists in town who will do
psychotherapy or supportive therapy for people with a brain
injury," he says. "They may have memory problems, for
example, and how can you do psychotherapy when they have
to be reminded each time where we had progressed to? The
answer is, you adapt your therapy to work more on reintegration issues: How do you get back to work? Isn't it frustrating
not making as much money as you're used to? Maybe you
can't drive, and that's dehumanizing. "
Labi says the TBl system was conceived as a continuum of
care- from the trauma intensive-care unit, through levels
of in-patient rehabilitation, from acute to long-term and on
to outpatient rehab.
It's a system that makes sense economically as well as
medically, says Glen Gresham, M.D. , professor and chairman of the medical school's department of rehabilitation
medicine, and director of rehabilitation at ECMC.
"For years patients were being sent out of state, all over
the place, because there wasn't any coordinated system close

For example, Teter says,
if a patient is immobilized by
his injuries, his joints can
become tight and bent with
muscle contractures, requiring surgery. And the whole
range of skills that often is
lost to a head injury takes
time to relearn.
That's why the TBI system employs a panoply of therapists, working as a team to decide how to work most
effectively with a particular patient. They include occupational therapists, physical therapists, speech pathologists,
recreational therapists , neuropsychologists, social workers,
case managers and the attending physiatrist.
And their work doesn't end at the hospital doors. "The
shortest piece of a rehabilitation is the in-patient program,"
Labi says. That typically is followed by continuing outpatient
therapy and monitoring. And the patient's family becomes
deeply involved, whether or not he ends up living with them.
Head injury happens not just to an individual, but to the
family as well. The person they knew and loved may be
irrevocably altered. They may have new care-giving duties

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�OCCUPATIONAL THERAPIST SANDRA SEILER HELPS CHAD STUDLE Y IN THE K I TCHEN .

to home," Gresham says. "It was just sort of a chaotic situation."
with a lot less care on the outside. "
The TBI rehabilitation system, he says, "put it all on the
"We're working with the insurance companies and the
basis of cooperation, so everyone could win. Particular hospigovernment to make this as efficient as possible," Labi adds.
tals are guaranteed of a role; the health department (which
"The financial climate in medicine with patients like this is very
pays for many patients' head-injury rehab) is pleased because
precarious. But our philosophy is that every patient deserves a
patients are not sent out of state, which is much more costly;
trial of rehabilitation regardless of their insurance source."
and private insurers are pleased because they feel they can
Sometimes that rehabilitation takes a turn even the best
depend on the cost-effectiveness of the care, that this consortium is interested in good
"The financial climate in medicine with patients like this
care and not just interested in
a big profit.
"This is a model of regional
1s very precanous. But our philosophy 1s that every
care that we're very proud of
and that we think can be a
model for the whole country."
patient deserves a trial of rehabilitation regardless of their
james A. Phillips, clinical
instructor and administrator
for the medical school's department of rehabilitation
insurance source. "
medicine, says having the Department of Health and private insurance carriers represented on the system's board of directors brings unity of
therapist couldn't have predicted. Anthony Delabio, whose
purpose instead of squabbling over fees.
parking-lot fall put him into a coma, is back to the books at the
"That's the cosmic glue that keeps things together," Phillips
University at Buffalo. He had been studying environmental
says. "At least we have reasons to communicate, which is not
science, but now he wants to get into a different field: medicine.
necessarily what's been happening elsewhere in health care. "
Delabio, who lives with his parents in Niagara Falls, still
He also notes , "The amount of money that we're spending
has some impairment. "I get distracted easily," he says. "And
in the hospital is only 20 percent of (a head-injury patient's)
memory is a problem. "
lifetime care cost. The real burden of care is when they leave
But he's in great physical shape, having taken up body
the hospital. The amount of care that the family has to give ,
building. He doesn't drink anymore: "I've been working so
or an aide has to give , is really more substantial. We're trying
hard on my rehab, I don't want to jeopardize it. " And the
to make the community aware of alternatives: assisted living
whole experience has changed him, not entirely for the worse.
centers, for example. lf we can improve a patient's function"It's made me grow up a lot," he says. " ow I have
ing by just a little bit, sometimes that means he can get by
direction in my life .... I know what I want to do ."

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�TRAUMATIC BRAIN INJURY RESEARCH FOCUSES
ON FUNCTIONAL OUTCOMES
much care patients will need after they leave the hospital. "
THE CLOSE ASSOCIATION between the medical school's
Labi will report preliminary results from the study at a
Department of Rehabilitation Medicine and the rehab proUB-sponsored international conference on head injury rehagrams in the Traumatic Brain Injury Rehabilitation System
bilitation, to be held at iagaramakes possible some important reon-the-Lake, Ontario, in july 1996.
search into an epidemic problem.
• RichardT. Linn, Ph.D. , under a
Two academic studies in
grant
from the ational Institute
progress:
on
Disability
and Rehabilitation
• Dr. Maria Labi has a grant from
Research
,
an
ann
of the U.S. Dethe federal Centers for Disease Conpartment of Education, is studying
trol and Prevention, now entering
individuals
who have sustained
its fourth year, to study head-injury
mild
head
traumafor example,
patients as they progress through
who
have
lost
consciousness
those
the rehabilitation system. Labi is
for less than 30 minutes after a
looking at the functional outcomes
blow
to the head. About 5 percent
of head injury over a long period of
of
the
people who suffer such ::1
follow-up care, and trying to idenconcussion, he says, continue to
tify risk factors for complications
have problems- attention deficit,
from such injuries.
headache,
fatigue, depression , anxi"By having this regional system,
etya
year
after the injury.
by identifying all the patients comNow
in
the
third year of the
ing into the system, we've been able
project,
Linn
is
seeking a way to
to collect data from the point of DR . MARIA LABI , JAMES PHILLIPS (LEFT) AND
predict
who
will
have such probimpact and follow them out for the RICHARD LINN , PH . D . (RIGHT).
lems and who won't. Patients who
rest of their lives," says james A.
agree to participate undergo a positron emission tomography
Phillips, clinical instructor and administrator for the mediscan within a couple of weeks of their injury, and Linn will
cal school's Department of Rehabilitation Medicine. "That
try to correlate the amount and areas of change in brain
study will be a benchmark for the rest of the country. lt will
function with later problems.
also give back to insurance carriers information on how

CUTHBERT SIMPKINS II , M.D . , {LEFT) ASSOCIATE PROFESSOR OF SURGERY AND DIRECTOR OF THE
VIOLENCE AND VICTIMIZATION PROGRAM , WITH RESPIRATORY THERAPIST JOHN GUAGLIARDI .

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�Michael Msall,M.D, receives 1995
Sir James Carreras Medical Award

in care, clinical research, education and
advocacy
for
children
with
neurodevelopmental disabilities. His
efforts include team approaches, family
supports and developmental interventions for children with Down's syndrome, cerebral palsy, spina bifida, congenital malformations, prematurity and
related neurodevelopmental disabilities.
His work was recently published in Clinical Pediatrics and the journal of
Perinatology. Msall is a member of the
Society for Pediatric Research.
The Robert Warner Rehabilitation
Center is a cooperative effort of families ,
rehabilitators and professional and voluntary not-for-profit community agencies, including Variety Club of Buffalo
Tent #7 and The Children's Guild.
The Sir james Carreras Award was
established in 1986 and honors the name
of Sir james Carreras, MBE, a former
president of Variety Club International
who still serves on its board.

ichael E. Msall, M.D. , associate
professor of pediatrics and rehabilitation medicine, has received the 1995 Sir james
Carreras Medical Award.
The award and an accompanying $10,000 prize are presented
annually by Variety Club International
to the physician who has done outstanding work in the field of pediatric
medicine during the previous year.
Msall was chosen to receive the award
from among 60 physicians nominated
from around the world. He is chief of
the division of developmental disabilities and medical director of the Robert
Warner Rehabilitation Center at The
Children's Hospital of Buffalo.
A UB faculty member since 1987,
Msall received the award for his efforts

UB medical student named to
academic medicine fellowship
niversity at Buffalo medical student Aisha Prim has been named
an Academic Medicine Fellow
by National Medical Fellowships, Inc.
Prim is one of 35 minority
medical students selected for the honor,
funded by Bristol-Myers Squibb Co. ,
and established by The Commonwealth
Fund, from among 90 students nominated by 58 medical schools.
The $6,000 fellowship funded her
participation in a summer research
project at Roswell Park Cancer Institute to study how certain components
of the immune response may help kill
tumor cells.
She worked with her mentor, Richard Bankert, V.M.D. , Ph.D., associate
chief of Roswell's department of molecular immunology and professor of
microbiology.
Prim will present her research findings at a threeday symposium in january.
Prim has received the
Buffalo Urban League
Youth Award and the
medical school's Dean's
Commendation Award
for Academic Excellence.
ln addition, she has received the Buffalo Foundation Award and the Special Merit Fellowship for
1993 to 1995, and is copresident of the UB Chapter of the Student ational
Medical Association.
Two former UB medical students , Andrea
Williams, M.D. , and
Yvette Vinson , M.D. , are
previous recipients of
the national award.

-!11'1'"'--...,..------......

Michael E. Msall, M.D.

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�SUNY trustees
namelJrouy-and-- -versrty~erecei~ed
a doctorate from the
, ,
,
Umversny of Mmnesota.
Hong distmgmshed professors
suk Ki Hong, M.D. , Ph.D., uB professor of physiology, was named a distinguished professor in january in recognition of his reputation and contributions to research.
A UB faculty member since 1975,
Hong also serves as director of graduate
studies in the department of physiology.
Before coming to UB, he was professor and chair of physiology at the University of Hawaii.
Hong's research interests lie in the areas
of renal and environmental physiology.
He has authored or co-authored

wo School of Medicine and Biomedical Sciences faculty members
have been awarded the rank of
distinguished professor, the highest in the State University of ew
York system, by the SUNY Board of
Trustees.
The rank is an order above full professorship and has three co-equal designations: distinguished professor, distinguished service professor and distinguished teaching professor.
The rank of distinguished teaching
professor was conferred upon Harold
Brody, Ph.D., M.D., professor of anatomy
and cell biology. The designation is
awarded to persons who have demonstrated outstanding teaching competence
at the graduate, undergraduate or professional level. Brody is a 1961 graduate of
the medical school, and has been a faculty member for 40 years, serving for half
of that time as chair of the department.
He has done research and published
widely in the field of neuroanatomy, and
has served on several editorial boards,
including that of Buffalo Physician.
As a Fulbright scholar to Denmark in
1963, he helped establish that country's
first cadaver donor program. He was one
of the founding members of UB's Center
for Aging and is past president of the
Gerontological Society of America. He
received the society's Robert W. Kleemeier
Memorial Research Award for Outstanding Research in Gerontology in 1978.
Brody left the anatomy department
chairmanship in 1991 to continue teaching, do research and to fulfill a lifelong
dream of establishing a MuseumofNeuroanatomy at UB. The museum, dedicated in january, has received national
attention and is being used actively for
education and research.
A graduate of Western Reserve University, now Case Western Reserve Uni-

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nearly 190 articles for scholarly publications and more than 40 textbooks,
monographs and book chapters
He has earned numerous academic
awards, including the Stockton Kimball
Award from the medical school for excellence in research, education and service, and a special citation for distinguished service from the japanese Panel
on Diving Physiology and Technology
of the U.S.-japan Cooperative Program
in Natural Resources.
Hong received a medical degree from
Yonsei University in Korea and a doctorate in physiology from the University of Rochester.

1995 Spring Clinical Day Awards given for research presentations

T

HIS YEAR'S FIRST- PLACE SPRING CLINICAL
D AY AWARD WENT TO HANI ABDEL-NABI ,

M . D. , AND HIS TEAM FOR " CLINICAL APPLICA-

TIONS OF W HOLE BODY PET FOG IN CANCER
PATIENTS" ( R IGHT) ; SECOND PLACE WAS WON

BY B IRGIT JURLANDER, M . D . AND HER TEAM FOR
" CORON ARY A NGIOGRAPHY AND B IOCHEMICAL
MARKERS IN UNSTABLE A NGINA PATIENTS"
(BELOW) ; AND T H IRD PLACE WAS AWARDED
TO H RATCH

L. K ARAMANOUKIAN , M . D ., AND

HIS TEAM FOR " D ECREASED P ULMONARY
N ITRIC O XIDE S YNT H ASE A CTIVITY IN THE
R AT M ODEL OF C DH" (R IG H T) .

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�THEN . . . . NOW

Medical school enjoys rtch African-Amellcan herttage
RECENT FOCUS ON UNDERREPRESENTED MINORITIES BUlL T ON A HISTORY OF_
" COLOR-BLIND" ADMISSIONS AND EDUCATION POLICIES FOR MEDICAL STUDENTS

!though early records do not indicate race , it is
University of Buffalo and completed his degree .
clear that black students attended the University of
Dorsette helped organize the ational Medical AssociaBuffalo School of Medicine before the turn
tion for black physicians and was a trustee at Tuskegee
of the century.
Institute in Alabama, which Booker T. Washjoseph Robert Love was described
ington built from a small normal school
in a newspaper article about the
into a nationally known institution with
school's 1880 commencement as an
1,500 students.
Episcopal clergyman who studied
Other early black medical school
medicine as "an auxiliary to his
graduates include Frank L.
ministerial calling," and was
Watkins , who came to the Uniidentified then as the Univerversity of Buffalo from Montsity of Buffalo's first black
gomery, Ala., graduated from
graduate. His intention was
the medical school in 1891 and
"to undertake under Bishop
died in Buffalo in 1921. Henry
Holly of the island of Hayti,
Harrison Lewis, who graduWest Indies, the introducated in 1918, was a member
tions of the church in San
of the university's first class
Domingo ," according to
in the College of Arts and
the commencement arSciences before he transticle. Love's later writing
ferred to the medical school.
exerted an important inPerhaps best known locally was W. Yerby jones , a
fluence on jamaican history, it was indicated.
graduate of the medical
Cornelius
athaniel
school's class of 1924, who
Dorsette, a member of the
lived in Buffalo for 50 years.
class of 1882, was the second
A prominent ophthalmologist, jones served as chief of
African-American to receive a
medical degree from UB. He was
staff of the former E. ] . Meyer
Memorial Hospital.
BookerT. Washington's physician,
and often was mentioned by WashMary B. Talbert, for whom the
ington in speeches as an example of
university's Talbert Hall is named ,
black perseverance and initiative.
was a native of Ohio who graduated
Born into slavery in onh Carolina ,
from Oberlin College in 1885 , married a
Dorsette was separated from his mother at
Buffalo bookkeeper and spent most of her life
two months of age. He was raised by his grandin Buffalo. Active in local and national organizamother and graduated from the Hampton Institute in
tions, she was chairman of the executive board and then
1878. Failing health forced him to
president of the ational Association
resign from the Medical College at
of Colored Women , and vice president
JOSEPH ROBERT LOVE
Syracuse. After regaining his health
of the ational Association of Colored
and being rejected by the University Medical College of
People. In 1922, a year before her death, she received the
New York City because of his race , he came to the
Springarn Medal from the AACP.

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�A

Spoonful

of

he airline industry is in trouble.
With utilization down , and many
airlines cutting back on both personnel and flights , airline executives have looked to successful industries as models for
their reorganization.
Here's what might
happen if airlines were
run like the medical
profession.

Humor

©

Stu

S i lverste i n ,

MANAGED CARE AIRLINES

The terminal is neat and clean, the attendants courteous, the pilots capable.
In the event of an emergency landing,

M . D .

HMO AIRLINES

Passengers arrive eight hours before their
flight after calling an "advice reservation desk" and then carry their seats out
on the tarmac. They then take seats to
the middle of the plane and flap
their arms and hum "Anchors
Aweigh. "
Film: "Any Which Way But
Up. "
MEDICARE AIRLINES

PEDIATRIC AIR

They have the largest budget.
Nobody can find the airport.
There are three committees
working around the clock to
figure out how to make the airport more accessible. Problem
is, the committee can't find the
airport either. All seats will be
first class, as soon as the seats are
installed.

Passengers walk out onto the
runway, a short man with a
bow tie hands them stickers
in between answering advice
calls and running to the back
to help deliver the food . Every
first-class seat is next to a
colicky infant and
breastfeeding mother.
The movie: "Sophie's Choice:
Augmentim"
Complimentary drink : Pediatri c cocktail: amoxicillin
and jack Daniels.

PSYCHIATRY AIR

First-class seats are couches.
Coach passengers break up into
small discussion groups. Flight
destination is "wherever you want
to go." Midway through the flight
the pilot announces "I am experiencing some turbulence, but
we aren't here to discuss me."
The movie: "julia Child: Cooking with
Lithium."

SURGERY AIRWAYS

The cashiers, flight attendants and pilots all wear
shower caps and shoecovers,
even though the flight isn't a
sterile environment. Midwa y
through the flight a steering wheel
and earphone piece are thrown out of
the cockpit, and you hear the pilot admonishing the crew, that "these aren't
the ones I iike to use. "
Th e movie: "A Broviac Runs Through It"
The meal: Nobody has ever eaten it.

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the pilot has to call an 800 number to get
approval to lower the oxygen masks.
They also have a fleet of Lear jets for the
CEO of the airline. The crews receive
lucrative incentives for talking passengers out of flying at all.

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Stu Silverstein , M.D., pres ident of Standup Medicine Seminars of San Francisco, California, and

Stamford, Connecticut , lect ures nationwide on humor and medicin e. He is also co-author of What
About Me?, a booh on growing up with a develop-

mentally di sabled sibling.

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�Fierro '66, inspiration for fictional, best seller M.E.
AS THE REAL-LIFE VIRGINIA CHIEF MEDICAL EXAMINER , MARCELLA FARINELLI
FIERRO SEES HER ROLE IN THE " KAY SCARPETTA" MYSTERIES AS "GREAT FUN"

r. Kay Scarpetta and Dr. Marcella modest about her role as the model for
Farinelli Fierro '66 are both bril- Kay Scarpetta. She is also quick to
liant medical detectives, forensic point out that she doesn't physically
pathologists who are among the resemble the fictional medical exambest in the business at unlocking iner. ''I'm definitely not 105 pounds
the secrets of the dead and letting and five feet tall with blue eyes," she
them tell the tales of how they
lived and died.
The fictional Dr. Scarpetta has
gained worldwide fame as the
heroine of Patricia Cornwell's
best-selling mysteries. The latest, From Potter's Field, follows
Scarpetta from Virginia, where
she is chief medical examiner for
the Commonwealth of Virginia,
to ew York, where she confronts her principal adversary,
psychopathic killer Temple
Gault.
While Scarpetta is fictional ,
she is, according to Cornwell,
based on her mentor, Marcella
Fierro, who is the real-life Virginia chief medical examiner. "1
consider her the best forensic
pathologist in the world, and she
has been a tremendous inspiration to me. "
During an interview promoting her new book, Cornwell told
a national audience how sur- Dr. Marcella Farinelli Fierro '66
prised she had been to discover a
woman serving as a medical examiner says with a laugh.
when she walked into the M.E.'s office
She also doesn' t followthe lifestyle
10 years ago. Cornwell, a former news- of Scarpetta, who is divorced and enpaper reporter, ended up spending five joys affairs with FBI agents. Fierro and
years working as a technical writer in her physician husband have two chilFierro's office and researching the op- dren , neither of whom is following
erations of a real-life morgue for her their parents' medical career path, almurder mysteries.
though their son is in law school and
Fierro considers her role in the best- is interested in criminal law. Their
selling mystery books "great fun" and is daughter is a legislative assistant to a

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orth Carolina congresswoman.
Fierro and Cornwell have become
close friends, and she remains one of
Cornwell's chief advisors, reading every manuscript for factual errors.
Growing up in Buffalo, where she
attended D'Youville College
and the University of Buffalo
School of Medicine and Biomedical Sciences, Fierro never
dreamed of serving as a mystery book heroine , or even
working as a pathologist.
"While in medical school 1
was very interested in internal medicine, but once I did
my pathology rotation I found
this area of medicine fascinating," she recalls. "I was also
inspired by the late Dr. Judith
Lehotay (formerly Erie
County's chief medical examiner), who was one of the first
female forensic medical examiners."
After medical school graduation in 1966, Fierro did her
internship and additional
training in Ottawa, Canada's
capital, where her husband ,
Robert, was in training as an
obstetrician-gynecologist. She
had two more years of pathology training at the Cleveland Clinic,
and another year of forensic pathology training at the Medical College
of Virginia. She was certified in fo rensic pathology by the American
Board of Pathology in 1975, becoming just the ninth woman certified
by the ABP in forensic pathology.
She served as Deputy Chief Medical Examiner for Central Virginia

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�············································· · ·········································· ~

for 17 years, followed by 18 months association's board of directors and
as professor of pathology at East the executive committee. Fierro is a
Carolina University School of Medi- fellow of the pathology-biology seccine, where she taught general and tion of the American Academy of Foforensic pathology. In 1994, Fierro rensic Sciences. She has also served as
returned to Virginia to assume her a consultant to the FBI and on a panel
current positions as chief medical studying gunshot wounds. She has
examiner and chair of the depart- been published in professional jourment of legal medicine for the Com- nals and contributed chapters to sevmonwealth of Virginia, and profes- eral books, and is currently editing
sor of pathology at the Medical Col- the second edition of a text on identification for the College
lege of Virginia.
of American
"Forensic
Patholopathologists.
gists are reAlthough
ally medical
detectives an~M~nr
a l1 o f
who are helpcases ining the living
volve
dead
by uncoverpeople,
she
is
ing the causes
philosophical
of death," she
about her work.
explained.
"lt all
"There are a
depends on
million ways
your focus.
to look at difWithout the
ferent cases,
information
and this field
we
have
requires crelearn
ed
your
focus.
Without
the
ative thinkthrough
paing and is
information we have learned
thology , for
never borinstance,
we
ing."
for
through
pathology,
would
never
Testifying
know what
in criminal
instance,
we
would
never
we know tocases is an
day
about
important
know what we know today
child
abuse
part of a foand how to
rensic
about child abuse and how to
recognize
pathologthe signs of
ist's job, and
recognize the signs of abuse."
abuse.
We
Fierro enjoys
are saving
the experi1 i v e s
ence.
through
our
work
and
that helps
"I regard the court time as an opporus.
We
also
owe
it
to
the dead
tunity to teach, to instruct the court,"
to
find
the
cause
of
death
and
she explained.
discover
the
killer
in
case
of
She is past president of the National Association of Medical Examin- homicide . "
ers and presently serves on the - s v o E a o R A H w 1 L L 1 A M s

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•

Stephen Kimatian '92,is 1994 Air
Force Flight Surgeon of the Year
tephen]. Kimatian, M.D. '92, has
been named 1994 Air Force Flight
Surgeon of the Year.
Kimatian, a flight surgeon with
the 16th Operations Medical Flight,
16th Operations Group, at Hurlburt
Field, Florida, competed against representatives from nine other major air
commands to win the annual competition for the Malcolm C. Grow Award.
Last year, Kimatian spent 189 days
supporting joint special and national
security operations in Bosnia, Somalia
and Haiti.
Kimatian was the first medical officer
to reach the scene when an Air Force
AC-l30H gunship crashed in the Indian
Ocean in March. After triagingand treating the survivors, and transporting them
to a avy vessel for further treatment,
Kimatian returned to the crash site to
coordinate mortuary affairs and collect
information as part of the interim accident investigation board.
Before activation of the 16th Operations Medical Flight, Kimatian evaluated
the contents of medical rucksacks and
medical Rapid Response Development Kits
used during deployments. He served as a
clinical instructor for medical technicians,
advanced cardiac life support instructor
and clinical advisor to joint medical planners preparing for training.
Kimatian entered the Air Force after
his graduation from the School of Medicine and Biomedical Sciences in 1992.
He completed his internship at Wilford
Hall Medical Center, Lack land Air Force
Base, Texas; the USAF Hyperbaric Medicine Course, Global Medicine Course,
Brooks Air Force Base; and Combat Casualty Care Course, Camp Bullis, Texas.
He served with the 55th Special Operations Squadron at Hurlburt Field until
activation of the 16th Medical Operations Flight in October 1994.

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�Arthur J. Schaefer, M.D. '47,wins
Lucien Howe Award

from 1954 to 1956 as chief of ophthalmology at hospitals in Korea and japan.
He was named technical advisor to
japan's first eye bank in 1955.
A specialist in ophthalmic plastic and
reconstructive surgery, Schaefer has
maintained a private practice in Snyder
since 1959. He has been a member of the
medical school's teaching staff since
1952, and is a clinical professor of ophthalmology and a clinical assistant professor of otolaryngology.
Schaefer has published widely in professional journals, and has been an invited guest lecturer in the United States
and abroad. Active in professional organizations, he is past president of the
American Society of Ophthalmic Plastic
and Reconstructive Surgery.
He is a fellow of the American College of Surgeons, the American Society
of Ophthalmic Plastic and Reconstructive Surgery, the American Academy of
Ophthalmology and the European Society of Ophthalmic Plastic and Reconstructive Surgery. In 1989, he was elected
chairman of the advisory board of the
American Society of Ophthalmic Plastic
and Reconstructive Surgery. He has been
a member of the editorial board of the
journal Ophthalmic Plastic and Reconstructive Surgery since 1985.

rthur J Schaefer, M.D. '47, anationally known ophthalmic plastic and reconstructive surgeon, has
received the Lucien Howe Award
for contributions to the field of
ophthalmology.
The award is presented jointly by the
School of Medicine and Biomedical Sciences and the Buffalo Ophthalmology
Society. Recipients are selected by a
national committee. The award was first
made in 1928 to Dr. Edmund B. Spaeth,
director of ophthalmology at the Wills
Eye Institute in Philadelphia.
Schaefer is the
22nd recipient of
the prestigious
award, and the
first Buffalonian.
He received the
award, a specially cast gold
medal, in ceremonies held
this past spring.
Howe was a
pioneering oph- Arthur J. Schaefer, M.D.
thalmologist and
researcher who practiced in Buffalo in
the late 19th and early 20th centuries,
and was a member of the UB medical
school faculty. In 1926, he founded the
Howe Laboratory of Ophthalmology at
Harvard Medical School, known worldwide for its research.
Schaefer graduated from Canisius
College, took his medical internship
and ophthalmology residency in Buffalo hospitals, and has spent most of his
career in Western New York. He started
the oculoplastic, lacrimal, orbital and
reconstructive surgical clinic and service at the former E. j. Meyer Memorial
Hospital in 1961. The service was the
medical school's first subspecialty clinic.
Schaefer served in the U.S. Army

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Paulette Smart '92,wins AMAI
Burroughs-Welcome award
aulette A. Smart, M.D. '92, has
received the 1995 American Medical Association/Burroughs-Welcome Leadership Award for leadership in community service.
A third-year resident in physical medicine at Ohio State University
Medical Center when the award was
made, she was one of 40 residents and
fellows selected for the honor that allows them to participate in the Ameri-

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can Medical Association meetings for
resident physicians.
One of Smart's goals is to be a mentor
to young people. She was active in the
Big Brother/Big Sister program when
she was a student at Pace University in
Pleasantville, N.Y. , where she received
her bachelor's degree in 1988.
While in medical school, she taught
physics on weekends to gifted high school
students, and participated in musical
groups that performed in nursing homes
and children's units. She also spent five
weeks in jamaica, West Indies, providing medical services to the less fortunate.
Smart joined other resident physicians in session at the AMA's annual
meeting in Chicago last june. She will
also attend the group's interim meeting
in Washington, D.C., in December.

Seibel '66,honored for years of
work at ECMC'strauma center
he Erie County Medical Center
Lifeline Foundation recently honored Roger W . Seibel, M.D. '66, at
the foundation's annual black tie
dinner dance. Seibel is ECMC's
clinical director for the department of surgery and also serves as director of trauma services and the burn
treatment center.
Seibel, affiliated with the medical
center since 1973, was influential in the
establishment of one of the first trauma
units in the country there. In 1989, the
New York State Department of Health
recognized the unit as the regional adult
trauma center for the eight-county Western New York area. The unit treats over
1,600 trauma cases annually.
Since 1989, Seibel has also been director of Western New York's regional
burn treatment center at ECMC- the
only one of its kind between Pittsburgh
and Rochester.
Seibel is a clinical professor of surgery

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�and clinical associateprofessor
of orthopaedics.
He has published chapters
in several books
and authored
articles in refereed journals. His
article, "Blunt
Multiple
Roger W. Seibel, M.D.
Trauma, Femur
Traction and the
Pulmonary Failure-Septic State," changed
the way trauma patients are cared for.
A 1966 graduate of the School of
Medicine and Biomedical Sciences,
Seibel began his residency program at
the former E.j. Meyer Memorial Hospital in 1967, and was drafted by the
United States Air Force in 1968. After a
year in Texas and a year in Vietnam, he
returned to Buffalo in 1970 to complete
his residency.

Franklin Zeplowitz '58, chief of staff and medical director of Our Lady of Victory Hospital, was honored
recently for his distinguished service by hospital president and CEO Albert Candino (far left), chairman
of the board, and retired Bishop of the Catholic Diocese of WNY Edward Head (center) and Bishop
Robert C. Wurtz (far right).

Irene Snow '80,among alumni
elected to medical society posts

The third woman physician to head the were Russell W. Bessette , M.D. , D.D.S.
organization since its founding in 1821, ' 76 , president-elect;
Franklin
she succeeds David Scamurra, M.D. Zeplowitz , M.D. '58 , vice president;
edraj. Harrison, M.D. '77 , secretaryeveral alumni of the School ofMedi- Snow is a diplomate of the American
cine and Biomedical Sciences have Board of Internal Medicine, and is cer- treasurer.
been elected officers of the Medical tified by the National Board of Medical
Examiners.
Society of the County of Erie.
As a member of the county medical
Irene S. Snow, M.D. '80 , clinisociety,
she has served as president
cal associate professor and chief
elect,
vice
president, secretary-treaof general medicine for Buffalo Medical
Group , was installed as president at the surer and as chair of the group's pubargaret Paroski , M.D. '80 ,
society's annual meeting held in June. lic health committee. She is also a
president of the Medical
member of the
Alumni Association, has been
Medical Society of
elected a vice president of
the State of ew
Erie County Medical Center's
York, the American
lifeline Foundation , a notMedical Association, the American for-profit corporation that raises
e sure to set aside time to celebrate the
Sesquicentennial at Spring Clinical Day, May
College of Physi- funds to develop programs and encians and the hance patient care at the medical
11 , 1996.
Sherwin B. uland , M.D., author of "How
Women Physicians center.
Paroski is clinical director ofECMC's
We Die ," will deliver the annual StocktonAssociation.
department
of neurology and an associAlso
elected
to
Kimball lecture.
ate
professor
of neurology.
one-year terms

Paroski '80,named vice president
of ECMC'sLifeline Foundation

Mark Your Calendars

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······ · · ····· ·········· ···· · · ····· ··· ··················· ····· · ··· ·· ····· ······· ···· ·····

Sesquicentennial Reunion Weekend set
EXT YEAR 'S REUNION WEEKEND AND SPRING CLINICAL DAY WILL COINCIDE WITH THE CELEBRATION OF THE

MEDICAL SCHOOL'S SESQUICENTENNIAL ANNIVERSARY , WITH REUNION CELEBRATIONS ON FRIDAY ,

MAY 10 ,

AND THE STOCKTON KIMBALL LECTURE ON FOUNDERS' DAY , SATURDAY , MAY 11 .

HAROLD J. LEVY, M.D. '46

Al ROWE, M.D. '46

MARVIN PLESKOW, M.D. '51

AllEN GOLDFARB, M.D. '51

JOSEPH KUNZ, M.D. '56

JOHN HODSON, M.D. '56

ROBERT REISMAN, M.D. '56

MIKE COHEN, M.D. '61

JARED BARLOW, M.D. '66

JOEL PAUll, M.D. '71

DENNIS NADLER, M.D. '71

JOHN BODKIN, M.D. '7 6

STANLEY BUKOWSKI, M.D. '81

BRIAN SAME, M.D. '81

PANO YERACARIS, M.D. '81

SANFORD LEVY, M.D. '86

PAUL HOLMWOOD, M.D. '86

SUSAN llnLER, M.D. '91

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�CLASS OF 1 946

CLASS OF 1981

CLASS OF 1 966

"Fifty years and still going strong!
join us and celebrate. So many
memories to share! "

Harold J. levy

"We would like to see you all back for
the 30th reunion. Looking forward to
reminiscing, renewing friendships and
the fellowship. Please join us. "

Chairman

Jerry Barlow

AI Rowe

Chairman

"It's been a rapid 15 years. Let's get
together and try to catch up. Hope to
see you in May '96! "

CLASS OF 1 971
CLASS OF 1 951

Morv Pleskow
Chairman

AI Goldfarb
Co-Chairman
CLASS OF 1956

Stanley Bukowski
Co-Chairman

Co-Chairman

"Can you believe it? Forty-five years!
Our class reunion- May l l , 1996.
Please, reserve this weekend! It's too
important to pass up. It will be great
fun to become reacquainted , renew
old friendships, and enjoy the warm
companionship we shared in the past.
Do your best to join together for this
very special celebration! "

"Why wait five more years7 Come to
Buffalo in the spring and relax with a
few choice classmates! "

"After 25 years it will be great to see
one another. Looking forward to our
Silver Reunion! "

Brion Some
Co-Chairman

"Enough time has passed so that at
least some of us will have grown up!
Hope that as many as possible will be
able to come and that all are well. "

Joel Poull
Co-Chairman

Dennis Nadler
Co-Chairman

Pono Yerocoris
Co-Chairman

CLASS OF 1 976

"Class of 1976- can you believe 20
years have gone by?! Come back to
your medical beginnings. There will
be only one 20th-year reunion. Don't
miss it! "

"Come back and see how the medical
school has changed and how all of us
have changed in 10 years. "

John Bodkin

Sanford Levy

Chairman

Co-Chairman

CLASS OF 1 986

"Forty years! It is time to celebrate! "

Andrew Gage

Paul Holmwood

Joseph Kunz

Co-Chairman

Co-Chairman

Co-Chairman

John Hodson

CLASS OF 1 991

Co-Chairman

Robert Reisman

"It's hard to believe that five years have
passed since medical school and that
some of us are still residents! I am
looking forward to seeing all of you for
a little wine , a few stories, laughs and
baby pictures. "

Co-Chairman
CLASS OF 1961

"Set aside the time and help us
celebrate the Sesquicentennial at the
school and our 35th reunion in
Buffalo, the weekend of May 10,
1996. "

Susan littler
Chairperson

Mike Cohen
Chairman

Ed Manning
Co-Chairman

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�1995 Alumni Achievement Awards made
IVE MEDICAL SCHOOL ALUMNI
WERE THE RECIPIENTS OF THIS
YEAR ' S ALUMNI ACHIEVEMENT
AWARDS .
ALL PICTURED WITH OUTGOING
ALUMNI ASSOCIATION PRESIDENT
RUSSELL BESSETTE '76 ARE : AT
TOP LEFT , HARRY METCALF ' 60 ;
AT BOTTOM LEFT , THOMAS
GUTTUSO ' 60 ; AT TOP RIGHT ,
ROLAND AND SIDNEY ANTHONE

'50 ; AND AT BOTTOM RIGHT ,
NORMAN CHASSIN ' 45 .

HURWITZ &amp; FiNE, P.C.
I ATTORNEYS AT LAW I
SERVICING THE LEGAL NEEDS OF THE HEALTH SCIENCES COMMUNITY
Managed Care • Purchase&amp;SaleofPractices • Business&amp;Tax.Planning • HCFASafeHarborRegulations
and Physician Self-Referrals • Contracts with Private &amp; Public Entities • Employee Relations Counseling
• Fringe Benefit Programs • Representation Before Government Agencies on Audit &amp; Business Issues
• Facility Finance and Construction • Credentialing and By-Laws • Hospital/Medical Staff Issues

Please contact Robert P. Fine or Lawrence M. Ross at 716-849-8900
1300 Liberty Building • Buffalo, New York

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�Harold Brody, M.D. '61, professor of anatomy
and cell biology and former chair of the
department, received the 199S Distinguished
Medical Alumnus Award from John Naughton,
M.D., vice president of clinical affairs and dean
of the School of Medicine and Biomedical
Sciences. The award, a specially designed
crystal bison, was presented at a dinner
honoring Brody in October.

~niuersit~ at ~uffalo meaical ~lumni ~irector~

UNIVERSITY AT BUFFALO

1

B-MONTH SES~UICENTENNIAL

C:

DESK CALENDAR

TIIE 1996 Universily al Buffalo Medical

elebrate 150 years of tradition with
the University at Buffalo 18-Month
esguicentennial Desk Calendar, an
elegantly designed calendar featuring
illustrations culled fi·om University Archives.
Each month's images-selected for their

Alumni Directory has officially been released!

character and
umguenesschronicle UB's
history. The
calendar comes
with a custommade lucite
holder and stand,
and is gift boxed.

Medical Alumni. Dislribulion has already begun for

Since Lhis is our Sesquicenlennial Edilion, you
won'L want Lo miss oui. It is not too late to order
your own copy of the directory.
This comprehensive new volume is a compJation
of tbe mosl current data avaJable on over 5,300

Lhose who reserved dreir copies early.
If you wish to place an order or have any
queslions about tbe directory, please contact our
publisber directly at the (allowing address:
CUSTOMER SERVIC E D E PARTMENT
B E RN A RD C . HARRIS PUBLISHING Co., INC.

22 KO GE R C E NT E R
NOR F OLK , VA

To order, please
call Stella Ryndak
at (716) 645-6969.

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23502

Or call t/1e Customer Service Department toll /ree at
1-800-877-6554

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�SPRING CLINICAL DAY

Spring Clinical Day and Reunion Weekend '95
EDICAL SCHOOL ALUMNI AND OFFICIALS GATHERED AT THE BUFFALO

MARRIOTT FOR THIS YEAR' S SUCCESSFUL SPRING CLINICAL DAY , FEATURING

STOCKTON KIMBALL LECTURER RICHARD KRUGMAN , M . D .

�AND

REUNION

WEEKEND

REUNION CLASSES FROM THE PAST 50

YEARS CELEBRATED IN GRAND STYLE AS

THESE PICTURES CLEARLY DEPICT .

�•

················ · ·········· · ········ · ··· · ·········· · ······················ · ··········· · ···
.

I

November. In ad-

19505
E

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A

R

D

of

SHANBROM '51 ,

Santa Ana, California, received an
honorary doctor of
science degree from
Allegheny College.
THOMAS
HAMILTON

elected president of the Buffalo

on March 8, 1995. He joins his

Surgical Society and secretary-

sister, Leah, 4 , and brother Paul,

establishing an an-

treasurer of the Medical Society

2 1/2.

nual award in his
name to honor fu-

of the County of Erie. She also
recently became a partner in the

ture leaders in the

formation of Delaware Surgical

field of palliative

Group, P.C.,agroupoffivegen-

pain and symptom

eral surgeons working at Millard

WILBUR
'69 ,

South and South west and Who's Who
in the World.

6

9

IRVING KOLIN '65 ,

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of Winter

Park, Florida, was invited to the

and named professor of pediatrics and radiology and interim
chair of radiology at the University of Iowa. He has six children
and one grandchild.

Governor's Institute in North
Carolina to present recent re-

7

9

0

5

naltrexone in the treatment of
alcoholism. Dr. Kolin also spoke
at Duke University's department
of psychiatry, where he addressed
the topic of neurotransmitter systems and the use of medication in
the treatment of alcoholism.

JOAN G lAM POLl '90 and CRAI G

were recently wed

NARINS '90,

in Scarsdale, New York. Or.
Giampoli completed her resi-

8

9

0

DAVIDS . K OU NTZ '81 ,

5
ofPhila-

Strong Memorial Hospital, in
ew York, where she

Rochester,

delphia, has moved from

was chief resident in pathology.

Hahnemann University Hospital to Temple University as asso-

She is a fellow in surgical pathology and cytology at Strong. Dr.

ciate professor of medicine and

arins completed his residency

director of ambulatory care

at Duke University Hospital in

there. He has two sons, David, 4,

Durham,

and Matthew, 18 months.

cardiology fellow at Strong.

SH I RA R UBINSTEIN '85 ,

search findings on the use of

5

dency at Vanderbilt Medical Center in ashville, Tennessee, and

of Iowa City,

tion of University Radiologists,

0

Fillmore Health System and St.

SM I TH

elected president of the Associa-

9

9

joseph Hospital.

Iowa, has been

new edition of Who's Who in the

third child, Michael Nicholas,

oring Dr. Milch by

II ' 57 ,

oflasVegas,Nevada, Marvin A. McMillen '75
has been listed in the

has been

dition, CHI is hon-

management.

P .

NEDRA HARR ISON '77 ,

directs

orth Carolina. He is a

R OSALIND N OLAN S U LAIMAN

married

of

the Child and Adolescent Out-

'91 ,

Wrentham, Massachusetts, has

patient Psychiatry Clinic at

M . D .,

been appointed chief of internal

Georgetown University, Wash-

cember 1994. She is expecting a

medicine at the Rehabilitation

ington , D.C. She will present a

baby this December. She is com-

Hospital of Rhode Island. Or.

paper at the American Academy

pleting her med-peds residency at

Sgalia currently practices inter-

of Child and Ado-

Baylor this year; her

nal medicine and cardiology in

lescent Psychiatry's

husband is finish-

Hopedale, Massachusetts. He has

annual meeting in

ing his ID fellow-

A RTH UR

C .

S G A LI A

'73 ,

A D E L S U LAIMAN ,

(Georgetown '90) in De-

medical

served on the faculty of the Uni-

ew Orleans. She

ship. They plan to

director ofHospice Buffalo, clini-

versity of Massachusetts Medi-

cal professor of surgery and ad-

cal School since 1978.

writes that she and
her husband love

where his father is

ROBERT A . M I LCH '68 ,

Washington, D.C.
Elaine Ziavras '85,

ambassador, for a

has

been named chief of surgery of

she adds, is in the

settling, probably

Michael Reese Hospital in Chi-

Georgetown

on the East Coast.

cago, Illinois, and professor of

ophthalmology

surgery and physiology at the

department.

junct clinical professor of family
medicine at UB's School ofMedicine and Biomedical Sciences,
has recently been named therecipient of the prestigious Award
for Lifetime Achievement from
Children's Hospice Interna-

practice in Oman,

MAR V IN A . M C M ILLE N '75,

University of Illinois at Chicago.

few years before

NAVY L T. PAUL D .

Rosalind Nolan Sulaiman '91

S EE MAN

'93 ,

is

currently halfway

He has been program director in

J EFFREY

surgery at the Yale Affiliated Pro-

STEI NIG '88 ,

commitment to children's hospice care. The award will be pre-

gram at Bridgeport Hospital, director of the surgical intensive

York, has completed a surgery

ment to the Mediterranean and

residency in Savannah , Georgia,

Adriatic seas and has been serv-

sented at a banquet during the

care unit at the West Haven

and is now a partner with

ing off the coast of Bosnia-

tional. Dr. Milch was recognized
for his personal contribution and

P .

of Lancaster , New

through a six-month deploy-

1995 CHI National Conference

OVAMC and clinical associate

South towns Surgical Associates.

Herzegovina aboard the dock

held in Washington, D.C. , in

professor of surgery at Yale for

He and his wife, Maria, had their

landing ship USS Gunston Hall.

the past eight years.

B

u

a

0

p

y

a

n

m

n

9

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PLANTING

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DR. DEVILLO W. HARRINGTON, class of 1871, knew how to make his money grow. In fact, this man who in 1905 provided $5,000 through
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FOR A CONFIDENTIAL consultation on making a bequest to the UB School of Medicine and Biomedical Sciences, or to receive
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STEPHEN A. EBSARY, JR.
Assistant Dean and Director of Development, School of Medicine and Biomedical Sciences

UNIVERSITY AT BUFFALO
UNIVERSITY AT BUFFALO
SCHOOL OF MEDICINE

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SUNY at Binghamton
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Cornell University
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University of Rochester
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                    <text>State University of New York at Buffalo School of Medicine and Biomedical Sciences, Winter 1996

�BUFFALO PHYSIC I AN

\olumc 30. '\umhcr I
ASSOCIATE VICE
PRESIDENT FOR
UNIVERSITY SERVICES

Dr Carole

~mnh

Petro

DIRECTOR OF
PUBLICATIONS

Timoth) j Conro\
INTERIM EDITOR

judson \lead
ART DIRECTOR

\Ian j hcglcr
ASSOCIATE ART DIRECTOR
"'cott l:ri&lt;.:kcr
PRODUCTION MANAGER
-\nn Raszmann Brown
STATE UNIVERSITY OF
NEW YORK AT BUFFALO
SCHOOL OF MEDICINE
AND BIOMEDICAL
SCIENCES

Dr John '\:aughton \tee Pre&gt;tdcnt
for Clmical \[fat". Dean
EDITORIAL BOARD

Dr John \ Richert Chatrman
Dr. \1artm Brecher
Dr. Harold Brod\
Dr. Richard l Colltns
Dr. Alan J Dnnnan
Dr Timoth' Gabrwl
Dr. James Kanskt ·
Dr. Charles \1a,;aro
Dr. Charles Pagancllt
Dr. Robert L. Rct&gt;man
Dr. Thomas Rosenthal
Dr. Stephen ~pauldmg
Dr Bradley T Truax

Dear Alumni and Friends,

N

ineteen ninety-six has arrived; thanks to the dedication and hard work of the school's
History CommiLLee, everything is in order to celebrate UB's and its medical school's
sesquicentennial. The committee, chaired by Dr. Ronald Batt and Dr. Harold Brod)
and ably assisted and supported by Dr. joyce Vana, has orchestrated a fine program
of events. The initial opening activities will be held on February 22, 1996, when the newly
completed Biomedical Research Building will be dedicated and the formerly undesignated
Cary-Farber- herman Addition will be named the Biomedical Educatio n Building. These acth·ities will be conducted from 10:00 a.m. till
noon. That afternoon, an academic convocation will be held in the
elegant Austin Flint Reading Room of the Health Sciences Library.
Thanks to the help of its director, Dr. Gary Byrd, and its excellent
staff, the room will be available from 3:30 to 6:00p.m. The uNY
Trustees and UB's president will confer an Honorary Doctor of
Science degree on Dr. Saxon Graham, Professor Emeritus of Social
and Preventive Medicine and the department's former chairman.
This will be followed by a major Harrington Lecture by Dr. Steven A.
Schroeder, president of the Robert Wood johnson Foundation.
These activities are already complemented by the publication of the Medical Alumni
Directory and by the publication of a special supplement in Business First dedicated to the
medical school's sesquicentennial. In early April, the pictorial history compiled by all
members of the History Committee and edited by Dr. Brody, Dr. Vana, and Dr. Richard
Lee will be available for purchase. Thanks to the efforts of Ms. joyce Buchnowski, an
im pressive flyer describing the book has been widely circulated.
A series of other events are programmed throughout 1996 and up to mid-year 1997.
We hope you will be able to participate in as many of the e,·ents as possible. \-tore
important, all of us who have worked on preparing the sesquicentennial hope you will take
the time to reflect on the significance of the school's past, its influence on you, and the

pcomi&gt;e' &gt;nd '"P""'ibili''" 'h" will

"~' &lt;n ~"~ '

....._,

TEACHING HOSPITALS AND
LIAISONS

Batana \.\ \1edtcal Center
Adem· Kclh
The Buffalo (,cneral il&lt;"pnal
.\ ltdwd Slta"
Buffalo \ .\ \1cdical Ccmcr
The Children\ Hospnal of Buffalo
Lric Count\ \1eclical Center

\!ern Hospttal
\1tllard Fillmore Hospnals
fnmh Sma
Roswell Park Cancer lnstnute
'-,i~tCr"t or Charity llo~pital
Dnuu~ \fc'Cwtln

&lt;0 The ~tate L 111\·crsll\. of :\cw York
at Buffalo
Bt4ffalo Ph\ \1(1&lt;111 IS publtshcd
quarterly b~ the State Lni\·cr..,it~· of
:\e" York at Buffalo ~chool of
\tcdtunc and Biomcdi&lt;:al St:icnccs

and the Office of PublicatiOns. It ts
.,t.:nt free of charge. toalumm , facultY,
students, re&gt;tdents and fnends. The
staff reserves the nghtto cdtt all COl"
and ..,uhmi-,"otons at:ccptcd for
puhliGttiOn .
\ddrcss quc ... tions, comments and
Eduor Bu(fcllo
Ph)\icicm, State Lnin:-rsuy of '\"n,

... ubmission.., to :

)ork at lluflalo . Unl\crstt\
Puhltcatll&gt;t". I 3{&gt; ( rofts llall,lluffal&lt;i,
'\c" York 1-+loO

Send address thanges Ia:

Buffalo
Pin siw111. Ho (I~ \ddt! ton . 34 35
\lam ~treel. Buffalo. '\e" York 142 1-+

j ohn aughton, M. D.
\!icc President for Clinical Affairs
Dean, Sclwol of Medicine and Biomedical Sciences

Dear Fellow Alumni:

T

he medical school's sesquicentennial celebration is well under way! We will keep you
posted regarding the various e\'ents marking this historic m ilestone (there is a
rou ndup on page 22). On February 22, 1996, we will ha\"C dedication ceremonies for
the opening of the Biomedical Research Building and the designation of the CaryFarber-Sherman Addition as the Biomedical Education Building.
In the ncar fu tu re, you wi ll be receiving a brief alumni sun-cy. The Board ofGo\'ernors
tries hard to represent the alumni at large, but wedon'tgettosee many
of you regularly, and we'd like to knO\\ what you're thinking. A
variety of topics will be covered and we really hope that you'll find a
few minutes to reply. If there arc any questions or topics you'd like
covered in the survey, please let me kno\\.
\Vhen I introduced Dr. 'laney Nielsen as a speaker at Spring
Clinical Day in 1993, I was O\-cmhelmed by the list of her accomplishmenLs. Well, get ready for another line on her C.V. I Dr. :\!ielsen
has been selected as this year·s recipient of the State University of New
York at Buffalo's most prestigious alumni award, the Samuel P. Capen
Award. Congratulations are also in order for Dr. james olan, who rcceml) retired as
chairman of the Department of Medicine! Dr. "lolan will recci,·e the Walter P. Cooke
Award, the university's award for notable and meritorious contributions to the uniYersity
by a non-alumnus.
I'm looking forward to seeing many of you at Spring Clinical Day in May.
Warmest regards,
~... a.
~

. - ()a.JtJZX

w.

T

~sJt.,;.

, MD

Margaret W. Paroski, M. D.

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IJ Research
II Hospital News

II Treating Violence e

ECMC's Trauma Center isn't
finished working with the victims of violence
when they are healed.

The doctor's in. Page 26.

m

Sleep Without Rest e At the Sleep Disorder Center
of Western ew York, patients may discover that
what ails them during the day is the result of what
they don' t know about their nights.

Medical School
· Then and Now
, A Spoonful of Humor
Alumni
Treating violence with more than
sutures. Page 6.

1

Classnotes

*James

ffiar~s.

m.~. '?l ta~es

t~e ~elm at
What happens once you go to
sleep? Poge 12.

t~e ~~~~r~.
rage{~.

�weight-loss treatment programs showed
that at 10 years, more than 20 percent of
the children had maintained a 20 percent decrease in overweight, compared
to fewer than 1 percent of the adults.
"These results suggest that as a public
health policy issue, it may be a better use
of limited resources to focus on preventing obesity in children, instead of
trying to reduce obesity after it is well
established in adults," says lead researcher Leonard H. Epstein, professor
of psychology, social and preventive
medicine, and nutrition at the University at Buffalo.
The study appeared in the September
1995 issue of Obesity Research.
Epstein, who heads B's Behavioral Medicine Laboratory and has
studied childhood obesity for more
than 20 years, is now working with
overweight children who participate
in a four-month comprehensive, family-based weight-control program
called the Stoplight Diet. The Stoplight Diet teaches children to ea t a
nutritionally balanced diet by linking foods to the three signals on a
traffic light: "red " high-calorie foods
should be eaten rarely; "yellow" moderate-calorie foods can be ea ten in
moderation; and "green" low-calo rie foods can be eaten freely. The
program combines diet with exercise, behavior modification , and a
maintenance program and is the only

Dorn receives NIH "FIRST"grant

treatment program in the country to
document success in children over
an extended period.
In the current study, Epstein compared treatment results of children and
parents from 113 families who had participated in behavioral weight-control
programs conducted by his group. Children and parents in these programs were
given similar diet, exercise, and behavior-change recommendations.
At six months, about 40 percent of
children and 20 percent of adults
showed at least a 20 percent decrease in
pounds overweight. While both children and parents regained weight after
this initial drop, children's weight gain
at five years stabilized at about 7 percent below baseline and remained there
at10 years. But adults returned to their
baseline weight by five years, and at10
years they weighed about 7 percent
more than they did at the beginning of
the study, results showed.
Epstein cited several factors that could
explain these results, including the nature
of most adult treatment programs. "Typically, adults are treated by themselves,
while children are treated within the family, which provides important support for
habit changes and maintenance." Other
reasons include the natural tendency of
children to be more active, a difference in
motivation in children and adults,
children's fewer number of fat cells, and
the fact that children's habits aren't as
deeply ingrained.
Epstein calls for more
studies to replicate
these findings and to
better understand the
mechanisms that may
be responsible for the
differences in effectiveness.
The research was supported by grants from
the ational Institutes
ofHealth. +
Leonard H. Epstein, Ph.D. (right}, meets with a CBS reporter.
LOIS
BAKER

oan Dorn, Ph.D. , research instructor of social and preventive medicine at the University at Buffalo,
has received a $350,000 five-year
First Independent Research Support and Transition (FIRST) Award
from the ational Institutes of Health.
The FIRST award is given to new researchers to support their first independent research project and help them
become competitive for traditional IH
grants.
Dorn's award is based on a research
proposal to investigate the role of physical activity in disease prevention. he
will conduct long-term follow-up and
analysis of two epidemiological studies
relating to this issue: a general population study conducted in Buffalo in the
1960s containing detailed health and
lifestyle information collected from residents of that city; and a multi-center,
randomized clinical trial conducted in
Western ew York in the late 1970s as
part of the ational Exercise and Heart
Disease Project that was designed to
study the effects of a regular, medically
prescribed, supervised exercise program
on the rehabilitation of survivors of a
myocardial infarction.
Dorn will determine the current status
of all original participants and the cause
of death of those who have died , and will
analyze various health factors determined
at one and three years and their relationship to long-term survival. +

Kids better losers than parents
he first study to compare weight
loss and weight-loss maintenance
in children and adults enrolled in
the same treatment program ha
shown that obese children take
pounds off easier and keep them
off longer than their obese parents.
The follow-up study of participants in

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�..•. .. . • . . . . . . . • . . . . . . . . . . . . . . . . . . . . • . . • . . . . • . . . . . . . . . • . . . . . . . . . . . . . . . • . . . . . . . . . . . . . . . . . . . •

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Study points to new treatment for
recurring UTis in women

ings held even when several months tant professor of nuclear medicine and
passed between recurrences.
pharmacy, says about 10 percent of the
"If our results are confirmed in fu- U.S. population experiences migraines ,
ture studies, they may have significant with women suffering the headaches
n a study of 23 women with recur- therapeutic implicarent urinary tract infections , re- tions for women with
searchers at the University at Buffalo recurrent
UTis ,"
have found that most patients were Russo states. "Data
being reinfected by the same strain from at least two preof E. coli bacteria that caused their vious treatment studinitial infection and not by different ies suggest that longstrains each time, as reponed previ- term remission can be
ously. In addition , they found that the achieved with antimibacteria causing recurrences in most of crobials in some
the women were harbored in the patient's women. We also
own intestinal tract.
know that certain anResults of the study were reported in tibiotics can eradicate
the August 1995 issue of]ournal oflnfec- bacteria in the fecal
tious Diseases.
flora better than oth"These findings give us a new under- ers. Given these constanding of the mechanism of recurrent siderations, further
urinary-tract infections," says Thomas data on the impact of
A. Russo , M.D. , University at Buffalo different treatment
Women suffer migraines three times more often than men.
assistant professor of medicine and lead regimens on longinvestigator on the study. "It's possible term cure clearly are needed. "
three times more often than men.
that alternative approaches aimed at
Migraines are thought to start with
A specialist in infectious diseases ,
eradicating a persisting strain from the Russo began the research while with the a narrowing of blood vessels in the
intestinal flora, and not just the urinary Bacterial Pathogenesis Unit of the NIH's brain , which decreases blood flow and
tract , would result in a long-lasting,
ational Institute of Allergy and Infec- can cause the flashes of light and dark
permanent cure," Russo says.
tious Disease. Also participating in the bar-like visual aura some migraine
Urinary-tract infections in women ac- study were Ann Stapleton, M.D., Tho- sufferers experience, Bednarczyk says.
count for an estimated 7 million office mas M. Hooton, M.D. , and Walter E. This vasoconstriction is thought to
visits a year, at a cost of more than $1 Stamm, M.D. , of the UniversityofWash- be followed by a widening of the blood
billion. About 20 percent of women ington-Seattle, and Suzanne Wenderoth vessels in the brain, or vasodilation ,
with an initial infection will develop of the ational Institutes of Health. + which causes the characteristic
recurrences , some as many as 20 a year.
pounding pain.
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Previous studies concluded that
o consistent relationship has been
more than 75 percent of the recurestablished between migraine symptoms
ring infections were caused by a new
and cerebral blood flow , however , acstrain of bacteria from an outside
cording to Bednarczyk.
source. Using a genomic-analysis
University at Buffalo researcher
His study will attempt to show such a
technique similar to D A fingerhas received a $114,000 two-year relationship by measuring cerebral blood
printing unavailable to earlier regrant to study the mechanism flow at three intervals-during a headsearchers , Russo 's group found that
underlying migraine headaches. ache episode, following treatment with
68 percent of recurring infections in
The research is funded by the De- sumatriptan, and during a headachethe 23 young women were caused by
partment of Defense, with funds free period-using positron emission
the same strain of bacteria that made available through the Women's tomography, or PET scans, which are
caused their first infection. The fig- Health Initiative.
extremely sensitive and allow researchure was 76 percent among women
Principal investigator Edward M. ers to monitor biological processes as
with the most recurrences. The find- Bednarczyk, Pharm.D. , research assis- they occur. +

Migraine study funded

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t!JJ
UB dental school helps set up
clinic for underserved children

First pediatric heart transplant
performed at Children's

he School ofDental Medicine at UB
is joining forces with Mercy Hospital and The Children's Hospital of
Buffalo to establish a pediatric dental clinic expected to serve 4,0006,000 children who currently receive little or no dental care.
The new clinic is expected to open in
February in Mercy Hospital's Marian
Professional Building. UB dentists
project that they will serve 1,500 children covered by Medicaid the first year.
"This project is a prime example of
how a successful health consortium can
work ," says Louis]. Goldberg, D.D.S. ,
Ph.D. , dean of the UB dental schooL
The new pediatric dentistry clinic
will be a six-chair expandable facility ,
managed jointly by the three participating institutions. The cost of the project
(approximately $375,000, including
equipment, computers, and furnishings)
will be shared by the two hospitals.
Dental students and residents will rotate through the clinic, with UB dental
school faculty serving as attendings.
Initially, only basic pediatric dentistry
services will be offered; oral surgery and
orthodontic services will be added as
resources become available.
"The Children's Hospital of Buffalo is
very excited about the new partnership
between Mercy , Children's, and the UB
dental school," says Mary M. Ward,
Ph. D. , vice president of clinical services
at Children's Hospital. "O ur joint-venture pediatric dental clinic on the Mercy
Hospital campus allows us to ensure
that the children of our community have
access to a pediatric dental network that
is responsive to their unique needs. "
Several other UB dental school outreach initiatives for underserved residents of Erie County and the Southern
Tier are currently under way. +

he Children's Hospital of Buffalo
was designated the Upstate New
York Regional Referral Center for
Pediatric Heart and Lung Transplantation in june 1995 by the
New York State Department of
Health. Three months later, on September 27, CHOB successfully performed
its first pediatric heart transplant.
The patient , ten-week-old Evan
Kentile , son of Mark and judy Kentile
of Claysville, ew York (near Utica),
was born in Syracuse on july 6 with a
severe congenital cardiomyopathy. Immediately after birth he was transferred
to CHOB's Level Ill eonatalintensive
Care Unit, where his case was managed
by neonatal and pediatric intensive care
teams. Once his condition stabilized,
he was approved for heart transplantation and his name was placed on the
national organ donor list. A donor became available at The Children's Hospital of Buffalo on September 26. The
heart was matched to Evan's specifications , and with the assistance of Upstate ew York Transplant Services,
the donor's liver was sent to The
Children's Hospital of Philadelphia for
transplantation .
Evan's heart transplant operation was
-LUCY
GARDNER
CARSON
performed by Eliot
Rosenkranz , M.D.,
chief of the Division of
Cardiovascular Surgery
at The Children's Hospital ofBuffalo, with the
assistance of orman
Lewin ,
M.D. ,
a
cardiothoracic surgeon
from the Department of
Surgery at Buffalo General Hospital. (T he
transplantation program at Children's was
developed in coopera- Eliot Rosenkranz, M.D., holds young transplant patient Evan Kentile.

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tion with the adult-based transplant program at BGH .)
"This initial transplant procedure
demonstrated the benefit of having a
transplant program at Children's Hospital equipped to deal with the most
critically ill newborns, " says Rosenkranz.
"This patient truly benefitted from the
availability of all aspects of high-intensity care and teamwork that have been
put together here ."
Evan was discharged from The
Children's Hospital of Buffalo on October 27. After remaining in the area for
several weeks to allow for continued
monitoring and regular follow-up examinations, he and his family returned
home to Claysville. They visited Buffalo
in December for a Christmas celebration at the Ronald McDonald House.
"Evan is doing very well after receiving his new heart, and has not experienced any significant complications,"
Rosenkranz says. "His parents can now
look forward to the opportunity to enjoy a long, healthy life together. "
Before CHOB's designation as the Upstate ew York Regional Referral Center
for Pediatric Heart and Lung Transplantation, such transplants in ew York State
were primarily provided at adult healthcare
systems in ew York City, or at out-ofarea pediatric medical centers in Boston,
Pittsburgh, and Cleveland. +

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�······ · ············· · ···· · ···· · ··········· · · ·· · · ······························ · ········· · · [ i ]

Western New York VA medical
centers complete merger
significant new partnership between the Veterans Affairs medical
centers in Buffalo, Batavia, and
Rochester became official in january, when the management structures of the three health care facilities completed their merger into one
organizational unit.
The Veterans Affairs medical centers
are being integrated into a single
healthcare system called the Department of Veterans Affairs Western ew
York Healthcare System (YAW YHS) .
Richard S. Droske, present director of
the Veterans Affairs medical center in
Buffalo, will serve as director of the new
VAWNYHS. "Our goal is to make the
best use of resources to give veterans the
best health care possible," he says.
Other goals of integration include providing a full continuum of care to patients, including primary care to every
patient, expanded clinic hours, additional points of access for care, and
decreased waiting times; better coordinating patient transfers and referrals;
processing admissions in a more timely
fashion; establishing one telephone
number that veterans can call for care,
information , and appointments; mak-

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ing patients'
medical files
available at
any of the facilities in the
integration;
and reducing travel for
veterans by
transporting
staff to provide specialized care at
the facility
closest to the
veteran.
The VAW YHS at Buffalo will continue to serve as the tertiary referral
center for patients from throughout
Upstate ew York and northern Pennsylvania, offering complete inpatient/
outpatient services and acute care. The
VAW YHS at Batavia will specialize in
comprehensive geriatric and long-term
care, but will continue to offer limited
outpatient and primary care services.
Patients in need of acute care and hospitalization will be treated in Buffalo.
Perhaps the greatest change will take
place at the VAW YHS at Rochester,
which presently consists of a small clinic
in the downtown federal building whose
space limitations preclude anything
other than providing the most basic
mental health and general medical outpatient services-to only 9 percent of
Monroe County's 64,000 veterans. The
Rochester outpatient clinic will soon be
relocating to a new building dedicated
solely to providing the area's veterans
with more complete health care services.
The goal of the VAW YHS at Rochester
is to double its annual patient visits to
55,000 within the first year.
Following national trends, all three
medical centers (plus the VA's satellite
center in Jamestown) will emphasize
more ambulatory surgical procedures
and outpatient care, and will expand the
use of physician assistants and nurse

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practitioners whenever possible, in order to cut costs and streamline service.
Cost savings realized through these
measures, and through integrating the
three medical centers into one management structure, will be reinvested into
patient care and making more services
accessible to more veterans. +
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Dawidson named transplantation
services director at BGH
he Buffalo General Hospital has
named Ingemar Dawidson, M.D. ,
Ph.D., F.A.C.S., DirectorofTransplantation Services.
Dawidson, whose clinical expertise is in kidney and pancreas
transplantation and vascular access surgeries, earned his medical degree at the
University of Gothenburg , in
Gothenburg, Sweden. After completing
his surgical residency at Sahlgren's Hospital in Gothenburg and his research
fellowship in surgery at Tulane University, Dawidson underwent renal transplant training at the University of
Gothenburg and earned his Ph.D. in
surgical physiology at the University of
Gothenburg Medical School. He then
underwent liver transplant training at
the University of ebraska Medical Center and pancreas transplant training at
the University of Minnesota Medical
Center.
A prolific contributor to research and
education (he has authored 123 abstracts
and has been the selected speaker at
more than 30 international lectures and
symposia), Dawidson is a fellow in the
American College of Surgeons, and a
member of the American Society of
Transplant Physicians, the American
SocietyofTransplantSurgery, the American Council on Transplantation, and
the Association of Academic Surgery. +

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�BY

JESSICA

ANCKER

Beepers sound in the corridors of Erie County Medical
Center's trauma center. A paramedic is signaling to the doctors, nurses,
and staff that his ambulance is bringing in a patient with stab wounds.
Minutes later, the doors swing open and a young man is wheeled in,
bleeding from scratches on his cheek and shoulder and from a third
deceptively small spot in the left side of his chest.
The two paramedics brief the doctors (" He says it was a six-inch
knife"). The patient writhes and asks if he can get anything for the
pain. "If we gave you something now, you'd just throw it up when you
go into surgery," a resident says.

PHOTOGRAPHY

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��An unceasing
thread of blood
The program has its roots in the
research of Simpkins, who found thatas he and other doctors had long suspected-assault victims were likely to
come back to the hospital many times.
"I kept noticing that I was operating
on the same individuals," Simpkins says. His research in
Washington , D.C. , and Baltimore found that 35 percent of
the victims of violence in the emergency room had been to
the hospital at least once before. Within five years , Simpkins
found, 44 percent of these patients would return to the
hospital after other violent episodes-and even worse, 20
percent would wind up dead.
"I realized operating on them wasn't getting to the root of
the problem," Simpkins says.
In Buffalo , ECMC head of surgery Roger Seibel was
noticing the same thing. During one two-year period, the
number of gunshot wounds, stab wounds, and other violence injuries skyrocketed by 50 percent. Many patients
were repeat victims. "It's a feeling of hopelessness just to
patch them up and send them back out," Seibel says.
&gt;\T \1A~'t HO~PITAL':J , that would be the end of the
Simpkins and Seibel teamed up with Karen Romano and
story. But at Erie County Medical Center, it's where a new
eville
Francis to create the Violence and Victimization
story begins.
Prevention Program in March 1994.
Before the patient leaves the hospital , social worker eville
Their first step is to take advantage of the patient's pain
Francis and surgeon Cuthbert Simpkins might come to chat.
and confusion to urge him to rethink his life.
And after the patient goes home, Francis will probably call to
"The best time to intervene
check in, and maybe suggest a
is when that person is in the
meeting.
hospital ," Simpkins states .
Those simple human con•PEOPI.£ T£ND TO B£ •
"They've got a tube in their
tacts are the beginning of the
chest-that
hurts. They've got
hospital's aggressive follow-up
a colostomy. They're scared. I
for assault victims , called the
try to make sure they're scared.
Violence and Victimization PreI tell them 'You almost died ,' or
vention Program. More than just
'You almost lost your leg."'
stitching up wounds and set"People tend to be a little
ting bones, ECMC's staff tries to
more insightful when they realize they came close to dying,"
rescue patients from the kinds of violent lifestyles that could
Francis agrees. "Coming close to death gives you a greater
land them right back in the emergency room.
"let's think of this as a demographic problem , rather
appreciation for life. "
They hope the pain and fear might be enough to make
than something that just happens ," says Karen Romano ,
even the toughest young man or meekest woman wake up.
ECMC's trauma nurse coordinator.
winds down along his ribs as he is
stripped, x-rayed , catheterized,
questioned , reassured. An anesthesiologist takes the young man's
hand and explains that the surgeons want to see if the knife has
nicked his heart. "We're going to put you under and do what
we call a pericardia! window, " she tells him. "How long will
I be out' " he asks nervously. "It depends on what they find.
More than likely it will be less than two hours, " she says. "But
I'm asking your opinion," he insists. "lf there's something
wrong, how long will it take? " She answers , "It's different for
every person."
He asks to make a call to his mother, and a young nurse
takes the phone number and relays his message. An operating room is cleared, and the flock of doctors and nurses
whisk the patient in.
The operation finds no damage to the heart, and in a few
hours he is stitched up and recovering from the anesthetic.

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�If it does, they're
ready to suggest
help.
For a drug
dealer wounded
in a street battle,
that might mean
substance abuse treatment, a trip to the welfare office, and
job training. For a battered wife, it might mean shelter, and
the emotional and legal assistance to help her get protection
from her spouse. For many patients, it means help getting or
keeping a job. "Unemployment is one of the risk factors for
violence ," says Simpkins.

That's when
he began to lean
on Francis for
help in finding a new job , and sometimes just for comfort.
"He's the best friend I have. Sometimes I feel like he's the
only friend I have ,'' Truitt says. "He's got an understanding
of me."
With Truitt's good job history and six years of Army
service, he was able to land another machining job. But after
a few days , Truitt said, he couldn't handle the heavy pieces
of steel with his weakened arm. His employer told him he
could come back after his arm regained its strength, but
when Truitt called after weeks of physical therapy, he found
the job had been filled.
''I'm still looking, I don't give up. But it's tough. Whatever color you are ," says Truitt, who is black, "it's tough ."
A natural optimist, Truitt will probably only need counseling and physical therapy to become one of eville Francis'
success stories. But Francis deals with tougher cases every
day, people who could spiral into poverty and end up as more
grim statistics in ECMC's emergency room.
The social worker's challenge is to find options for even
the toughest cases: the young drug dealers who don't want to
let down their macho street image, the battered women who
are too scared to leave their spouses, the people who haven't
held a steady job in years.
Francis draws on his own varied experiences to connect
with his clients. A native of Jamaica who emigrated to
Toronto as a teenager , he
worked in a factory for 12 years
until the plant closed down and
laid him off.
"It was scary , and that's
how I know how some of
these people feel , " says
Francis , a tall man who wears
dreadlocks pulled into a ponytail above a casual jacket
and tie . "I do identify with struggling people . I know
the frustrations of being there. I know what it's like
being on the outside looking in. "
But he also knows that it's possible to take advantage of
misfortune , a lesson he tries to impart to his clients. When he

Bt.,FFA.LO RESIDE T GREG TRLITT was barely conscious under a turban of bandages when Francis first
visited him. Two robbers had smashed his head with a
board and grabbed his knapsack and wallet as he was
walking home from a Fourth of July picnic.
"I didn't even have any money in that wallet," says Truitt.
At first, Truitt didn't think he had anything to talk to a
social worker about. As soon as his head felt better, he was
planning to go back to his good job, his girlfriend, and his
two little children.
But the next month, the manufacturing facility where
Truitt had been doing lathe work went bankrupt. Also, Truitt
realized his injury was worse than he had thought when he
self-confidently checked out of the hospital against his doctor's
advice. The head injury had left
lasting nerve damage in his right
arm and hand that robbed him
of strength and made his hand
clench up unexpectedly during
work. He was also pursued by
unexplained fears.
"I was getting ready to cross
the street and go between the
cars, and I couldn't do it. My
buddies were across the street, saying, 'Come on, man ,' and
I just couldn't cross the street," recalls Truitt, a small,
energetic 32-year-old who talks about his problems with a
kind of exasperated wonder. "It's like being a kid all over
again. Completely helpless."

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�was laid off, Francis went to school, earning first a bachelor's
degree and then a master's in social work from the University of
Toronto. He conducted street workshops on AIDS and worked
with the boys who accompanied their mothers to a battered
women's shelter before joining ECMC in March 1995.
Francis tries to approach every one of the 500 ECMC
patients each year who are victims of violence, and tailor a
unique approach for each.
Some just need jobs, and the
hospital's fledglingjob bank has
provided housekeeping and cafeteria work at the hospital and
at the University at Buffalo. But
for someone who has
been without work for
a long time , job placement isn't enough. The
social worker will talk
about the responsibilities that work entails,
such as showing up every day, and calling in
sick rather than just
staying home. Sometimes he even drives
his clients to work.
Francis recalls driving one client to her
first day on a new job.
She became very quiet
in the car, and finally
admitted that she was
Cuthbert Simpkins. M.D.
so nervous that she
might never have made it alone. "We're talking about people
doubting that they can live up to the experiences and
responsibilities of working," Francis says. "But she ended up
doing very well. "
His job might also include visiting clients' homes and
getting to know their families, visiting the welfare or unemployment office with them , or persuading an employer to
hire someone with a prison record.
lt also includes being patient. One man recovering from
a drug-related shooting said he had no interest in talking to
Franci . But two weeks later, he called and said, "What was
that program you were talking about? " Francis was able to
get him involved in drug rehabilitation , and hopes that he
might be ready for a job soon.

he tells how bigots bombed his family home when he was
a child because his father was helping to register blacks to
vote. Even before that horrific moment , which forced the
family to leave their Louisiana hometown , he recalls that
the library wouldn't let him in because he was black.
These experiences , as well as his experiences with his
patients, have helped convince him that American society is deeply violent.
"There's a willingness at all
levels of our society to use the
tools of violence that are advantageous to them-whether
it's the pen or the sword," he
says.
Middle-class families ,
he believes, are likely to
express violence by
sniping at their spouses,
criticizing their children, or firing their employees. The poor tend
to use guns, knives , and
fists instead of just
words , so they are more
likely to land in the
emergency room. Furthermore , Simpkins
says, generations of oppression have forced disproportionate numbers
of blacks into poverty
and the violent lifestyles
it can engender.
As a first step to their overhaul of society, the staff of the
violence prevention program created a videotape aimed at
children. Filmed with the help of a local television station,
the video traces four patients as they enter the emergency
room, bloodied and battered; watches surgery in gory detail;
and listens to the patients afterward as they talk about the
violence and wish they had led different lives. Karen Romano
and eville Francis, who take the film to the city's classrooms every week, say the patient that makes the biggest
impression on kids is a young man who was crippled by a
bullet and now must use a wheelchair.
ln the long run, Simpkins wants the violence prevention
program to launch the same type of peaceful revolution his
father sought through voter registration.
"l'd like to see the community organize itself. Register
people to vote , take their fate in their own hands. Then
l think we can see the community solve some of its own
problems," he says quietly. "l don' t think we can really
solve this problem until our entire country has a differ-

r------------------------,

THf C.RC\TORS OF THE \!OLE CL PRE\ E TIO
program share a conviction that their work should be part of
a greater overhaul of society.
Simpkins, who is also black, doesn' t sound bitter when

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�FRANCIS TRIES •

en t sense of interpersonal relations . I
think we need a higher moral and ethical plane."
eville Francis puts it more simply.
"The problem is in the community, but
the solution is also in the community."
For now, the program's staff is taking it
one patient at a time.
"Let's say you get 400 patients who
come in to the emergency room injured
because of violence or a violent lifestyle. If
you can getlO patients out of your 400 to
change, that's something to start with,"
Karen Romano says. +

Trauma Center -

Life-saving teamwork

The violence prevention program is just one example ofthe smoothly
running support structure that underpins ECMC's trauma center. "We
have a commitment from generalists and specialists to come in any
time of the day or night to take care of trauma patients," says Karen
Romano, the hospital's trauma nurse coordinator.
The planning begins well before a patient is admitted. Paramedics
or emergency medical technicians decide whether to bring a patient to
ECMC based on state guidelines, including severity of injuries, extent
of damage to the car in a car accident, and minutes away from the
hospital. They then dial a number that reaches a network of beepers
throughout ECMC. The beepers can display a simple message of what
the injury is and how soon the patient will arrive.
Incoming patients are brought to one of the trauma rooms, directly
inside the emergency wing's doors. Each trauma room is equipped with
portable x-rays and sonograms, lights, and surgical equipment. Once
patients are diagnosed and stabilized, they con be sent to one of the
operating rooms, intensive care units, radiology rooms, or other
facilities clustered in the immediate area.
Asurgical "pod," a corridor with nine small rooms branching off it,
is available for patients whose injuries aren't as severe, and doctors in
a similar medicol"pod" care for non-emergency illnesses.
The emergency wing is designed to make it easy to get patients
from one specialty area to another. Dr. Roger Seibel, who worked with
the architects who built it, says it is being redesigned to make

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movement even easier, and to add more space for outpatients and
their families.
The trauma system also provides services for recovering patients.
Special outpatient rehabilitation areas provide such services as specialty dressings, water tub rehab, counseling, and occupational and
physical therapy.
Crucial to the center's work is its staff. All nurses have advanced
training in trauma care and cardiac life-support. Residents receive onthe-job training from senior doctors, including many who have been in
trauma care their entire careers. The staff evaluates cases in weekly
and monthly morbidity and mortality meetings. Equally important,
Karen Romano says, is the fact that they receive emotional support
from one another. The ecstatic high of saving a life and the crushing
disappointment of losing a patient create an atmosphere of both
tension and camaraderie, she says.
"It's very physically demanding and emotionally demanding to
see, for instance, ayoung person permanently disabled," says Romano,
who practiced critical care nursing before taking over as nurse coordinator. "It really does toke a special breed to practice in trauma."
ECMC's 1,600 trauma patients come from all walks of life and have
every conceivable injury and illness. The average age is 31 ; 75percent
are men. While car accidents cause the greatest number of injuries
(538 in 1994 ), assaults with guns, knives, fists, and other weapons
come in a strong second with a total of 419.
--::JA

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�b y

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THE HYPOTHETICAL truck driver,
taking micro-naps at 65 miles per hour
and headed for disaster, has thousands
of very real counterparts on the road
who are excessively sleepy because sleepdisordered breathing is waking them up
hundreds of times every night-and they
don't even know it.
The ew England]ournal of Medicine
editorial was prompted by publication
in the same issue of findings from the
largest population-based study of obstructive sleep apnea that had ever been
conducted. Sleep studies of 602 employed men and women between the
ages of 30 and 60 revealed that 4 percent
of the women and 9 percent of the men
in the group had a level of breathingrelated sleep disturbance that would
warrant treatment.
Edwin Manning, M.D., clinical professor of neurology and director of the
Sleep Disorder Center of Western New
York, says that sleep problems are still
misdiagnosed or under-diagnosed, although awareness of them has increased
greatly in the past 15 years.
"There was a survey done at Stanford
recently that found that in 1980 something like 80 percent of persons presenting a certain set of symptoms were
diagnosed as depressed ," Manning says.
"By 1985, physicians considered 50 percent of the persons presenting the same
symptoms were depressed and 50 percent had some kind of sleep disorder. By
1990, it was recognized that only 5
percent of this population was actually
depressed. "
On a ovember afternoon, Manning
explains obstructive sleep apnea in a
small observation room as a technician
monitors a patient sleeping in an adjacent bedroom. The patient is an overweight middle-aged man; the sleep study
is run during the day because he is a
shift worker.
As far as the patient is concerned, he
is asleep. But there are a number of signs
that the sleep is not peaceful. The EEG
readout crawling across the tee h n ician 's
computer screen shows the tight amplitude of stage 2 sleep. His heart rate ,
audible from the EKG , is slowing noticeably; his blood oxygen level is dropping rapidly toward less than 70 per-

d

Anyone who sees a long-haul tractor-trailer driver
nodding over the wheel as he barrels down the
Interstate after ten years without a single restful
night's sleep would call his situation , at the least,
potentially catastrophic. But as Eliot Phillipson,
M.D., pointed out in a 1993 editorial in the New
England Journal of Medicine, "Ten to fifteen years
ago, obstructive sleep apnea was considered to
be a medical curiosity that was of little importance, and snoring was more a subject of humor
than one of serious scientific curiosity. "

Images

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�Sleep

has an architecture that was
only discovered beginning in the 1950s
when a University of Chicago graduate
student started running EEG tests on his
eight-year-old son and found brain-wave
activity that resembled a waking state
during certain periods of sleep. These
periods, coinciding with the eyes darting rapidly from side to side beneath
closed lids, we now know are dreams;
the sleep stage is REM, for rapid eye
movement.
The normal sleeper passes through
four stages of increasingly
deep non-REM sleep: stage
1 being a barely sleeping
state of drowsiness, stage
4 being a profoundly deep
sleep characterized by
delta waves. During these
four stages, the sleeper
maintains muscle tone. After an hour to an hour and
a half, the sleeper moves
back to stage 2 and enters
a first episode of REM
sleep: brain activity increases dramatically; heart
rate, respiration, and blood
pressure all go up; but the
muscular system is effectively paralyzed. As the
night proceeds, the sleeper
cycles through stages 2, 3,
and 4 and REM sleep, with
the lengths of REM sleep
increasing while delta
sleep decreases.
Persons who suffer repeated arousals
throughout the night never achieve stage

The patient is in the sleep center
cent. He is not breathing, but the instrumentation on his chest and abdomen because he reported to his physician
that he is leepy all the time during
record that he is trying to .
Then a loud snort is broadcast into the day. Indeed , excessive daytime
the observation room from a micro- sleepiness is one of the most comphone on the headboard. The EEG bursts mon presenting complaints related
into activity, the heart rate shoots up to to sleep disorders. And such a com80, and the blood oxygen level begins to plaint is far from a triOing inconverise. The readout from a thermistor at- nience: a report prepared for the
ational Commission on Sleep Distached under his nose shows that he is
orders
Research and published in
breathing again.
"He's awake now, but he doesn't know Sleep, in 1994, estimates that for the
year 1988, the total cost of accidents
it," Manning says.
On the video monitor,
the patient is lying on his
side, head on an outstretched arm, his other
hand tucked under his
chin, apparently soun d
asleep. Hi EEG quiet
back to the relatively uneventful trail of stage 2
sleep. Then, after a few
seconds, he stops breathing again. His heart rate
and blood oxygen level
start to drop. The cycle of
arousal and return to sleep
repea ts regularly about
every 30 seconds.
"His upper airway relaxes until it collapses
completely after a few seconds of normal breathing.
Then he tries unsuccessfully to breathe until the
effort arouses him ," Man- Edwin Manning, M.D.
ning says, watching another sudden related to sleepiness in the United
burst of brain activity. "He may be States was between 43.1 billion and
$56.02 billion.
waking up 300 times a night. "

"Wherefore to some, on being abed, they be taken to sleep, presently in
arms and legs leapings and contractions of the tendons , and so great a
restlessness and tossings of their members ensue that the diseased are
no more able to sleep than if they were in a place of greatest tortu re. "

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�"His upper a ir way relaxes until it collapses completely after a fe w
seconds of normal breathing. Then he tries unsuccessful ly to brea t he
until the effort arouses him, " Manning says, watching another sudden
burst of brain activity. "He may be waking up 300 times a night. "

4 sleep. This deprivation
is associated not only with
sleepiness during the day,
but also with diminished
cognitive functioning and
memory loss.
"Obstructive sleep apnea
is primarily a mechanical
problem, so we use mechanical interventions to
treat it, " Manning says.
"Conservative treatment includes such things as weight
loss, correcting posture, and
smoking cessation. "
A more aggressive intervention , for those who
can tolerate it, is to splint
the upper airway by the
application of continuous
positive airway pressure
(CPAP) through a mask or
nasal splint. A small com- Francis Gengo, Pharm.D.
pressor is used to supply
air at between 4 and 20 cc of pressure.
located
While such a device (which produces in the Dent eurologic Institute at
the sensation of being slightly inflated) Millard Fillmore Hospital, runs approximight well bother a person not suffering mately 1,000 sleep studies a year, operobstructive sleep apnea, Manning says ating 24 hours a day with a technical
that it can produce dramatic results for staff of eight. The center has four sleepsome of the patients he sees at the sleep ing rooms , outfitted with double beds
and other furniture to be more homecenter.
''I've had patients who have been than hospital-like. Patients bring their
chronically sleepy and lethargic for years own sleepwear. It is, naturally, a quiet
wake up here after one night with CPAP work environment.
For a typical overnight sleep study,
intervention bursting with energy ," he
says. "They tell me they've had their first the patient arrives in the evening, gives
good night's sleep in years. " Surgery is a a brief history, changes into sleepwear,
treatment option for a small group of and then is fitted with an array of electrodes on the scalp , beside each eye, and
patients.

The sleep center,

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on the chin, the chest, and
both legs; a thermistor under the nose ; an oxymeter
on one finger ; and belts
around the chest and abdomen-these produce what
is called a polysomnographic record. Although
sleeping in a strange place
and so thoroughly instrumented can cause what center technical director Thomas Maurer refers to as "first
night effect, " getting patients to sleep is not a significant problem: after all,
the reason most patients are
there is that they are too
sleepy . In the morning ,
patients complete a questionnaire that asks about
such things as how long it
took to get to sleep and the
quality and duration of the
night's sleep.
"Some people have poor perception
of their own sleep," Maurer says. "Some
patients will report that it took two
hours to get to sleep when the sleep
study shows that it only took 10 minutes. "
Technicians can monitor two studies
simultaneously, watching data on a split
computer screen and the sleepers on
two video monitors. Data from a sleep
study is scored later, with technicians
paging through computer screens, each
one of which shows 30 seconds of the
study, to record arousals, oxygen levels ,
heart rate , and other pertinent condi-

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�"We ' r e one of j u s t a h and f u I of centers 1 n the co u ntry- and the on Iy
one in New York-where the pharmacological studies look at both
sleep a nd daytime effects , the real-world end-points of drugs that
suppress the central nervous system, " Gengo says.

tions; screens that show significant
events can be printed out. The days of
turning pages through thick sheaves of
pen tracings ended when the center
computerized its data management in
1992 after running both ystems in parallel for six months.

ManningsaySthatsleepdis-

(The sleep center has conducted clinical
studies of the drug's effect on both sleep
and next-day psychomotor performance-see box , facing page.)
As for melatonin , which is enjoying a
vogue as a sleep-inducer, Manning says
that there is evidence that it has a role in
directing the time relationships in sleep
and that it can be of some help in controlling sleep problems related to jet lag

orders fall into four broad categories:
not being able to get to sleep or stay
asleep, excessive daytime sleepiness,
sleep-wake schedule disorders, and
abnormal behavior and activity during sleep.
Because everyone, at one time or
another, has trouble falling asleep or
staying asleep, a popular poll would
probably name insomnia as the
nation's number-one sleep problem.
The aggre sive advertisement of overthe-counter sleep-inducing medications reinforces the belief. But the
medical approach to insomnia is
changing.
"U ntil fairly recently, 15 percent
of all prescriptions written were for
Polysomnographic technician Pam
sleeping pills," Manning says, "but
Farina scores the digital record of a
that's beginning to decline."
sleep center patient's night.
Manning, who lectures on sleep to
first-year medical students at UB, tells
them that 70 percent of insomnia prob- and other sleep phase disorders. But
lems can be solved without medication Manning would discourage long-term
by a regime of proper sleep hygiene. use of melatonin because its other acManning's first commandment for get- tivities in the body may interfere with
ting to Jeep: "If you can't get to sleep, get reproduction and complicate heart disout of the bedroom." For transient ea e; another problem with the unreguinsomnias that need medication, Man- lated nostrum is that consumers can't
ning favors the relatively new, rapid- be sure what they are buying.
Excessive daytime sleepiness may be
acting non-benzodiazepine zolpidem.

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caused by various disturbances of a
person's sleep, by chronic insufficient
sleep, or by narcolepsy, the condition
that causes a person to drop off to sleep
suddenly during the day, sometimes directly into REM sleep; these episodes
are often coincident with the experience of a strong emotion.
A patient being tested for
narcolepsy will spend a night at the
sleep center for a regular sleep
study, and then the following day
undergo a Multiple Sleep Latency
Test (MSLT) . This test consists of
taking four or five 20-minute
naps , two hours apart, to determine how quickly the patient goes
to sleep and how quickly he or
she moves into REM sleep.
Achieving REM sleep during two
of five naps indicates that the patient suffers from narcolepsy. The
MSL T can show that a person is
excessively sleepy-rapidly
achieving stage 2 sleep in all four
nap sessions but never REM
sleep-indicating some factor
other than narcolepsy.
The abnormal behavior during
sleep-or parasomnia-that Manning sees most frequently at the sleep
center is sleep myoclonus, or periodic
movements in sleep. In this disorder,
the sleeper's legs jerk periodically during non-REM sleep, causing brief arousals from sleep and disturbing the normal sleep architecture by decreasing
stage 4 sleep. The movements stop during REM sleep.
Periodic movements in sleep are as-

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sociated in some cases with a condition
called restless legs that particularly bedevils some persons before and during
the onset of sleep. Manning likes to cite
a description of the condition written in
1685 by the London physician Thomas
Willis: "Wherefore to some, on being
abed , they be taken themselves to sleep,
presently in the arms and legs leapings
and contractions of the tendons, and so
great a restlessness and tossings of their

members ensue that the diseased are no
more able to sleep than if they were in a
place of the greatest torture." Fortunately for its sufferers, the condition of
restless legs responds to treatment with
dopamine.
The key to treating any of the
many sleep disorders-from the sleep
that won't come , to the sleep that
gives no rest-is discovering that
the problem exists.

"There are many, many people suffering from sleep disorders who don't
feel they can discuss them with their
physicians, " Manning says. "People
spend about one third of their lives
asleep and for those who have problems
with sleep there is often a remediable
underlying cause. Physicians should be
aware of sleep disorders and aware of
the public health consquences of sleep
disorders. " +

Sleep Center Drug Research
Cows mooing and dogs barking are not something one would expect to hear in the
usually quiet corridor of the Sleep Disorder Center of Western New York. But they do
occasionally disturb the center's morning peace as road hazards that test the
alertness of volunteer subjects negotiating a virtual highway on a driving simulator.
Gengo, who is the author of Drug Effects on Human

In addition to diagnosing sleep disorders, the center
maintains an active program of pharmacological research

Functioning and numerous papers, has pioneered an ap-

under the direction of Francis Gengo, Pharm.D. , associate

proach to clinical studies that uses one drug as a marker

professor in the departments of pharmacology and neurol-

for evaluating another. Alcohol is an obvious marker for

ogy and director of neuropharmacology at the Dent Neuro-

comparative assessments of psychomotor impairment,

logic Institute. Gengo's group is as interested in their

and Genge's group has done extensive testing to establish

subjects' waking state as in the contours of their sleep.

the magnitude of effect of different blood alcohol levels.

"We're one of just a handful of centers in the country-

B

"We can now say that the effects of a certain amount of

and the only one in New York-where the

..,.....,.,..,._ benadryl are equivalent to the effects of a

pharmacological studies look at both sleep

certain amount of alcohol," he says.

and daytime effects, the real-world end-points

In current studies, Gengo is comparing the

of drugs that suppress the central nervous

effects of Zolpidem, Tamazepam, an over-the-

system," Gengo says.

counter antihistamine-based sleeping aid, and

During sleep studies, Gengo 's research

a placebo. Because the effects ofTamazepam

group uses polysomnography to look at the

have been fairly well studied, it serves as the

effects of different drugs on such things as
the time of sleep onset and the character of -·~------'-

two nights, the first at home and the second in

marker for Zolpidem. Subjects are treated for

the ensuing sleep. In the morning, psychomotor tests

the sleep center, and then undergo a battery of waking-

reveal the subject's ability to think clearly and react

state psychomotor tests. The over-the-counter sleep aid

quickly. One such testing device is the driving simulator.

causes the greatest morning-after impairment.

Gengo has used it to establish baseline data that helps

For studies of the effects of certain drugs not intended to

to determine the relevance of psychomotor impairment.

promote sleep--such as muscle relaxants or deconges-

"There has been a lot of research that looked at the

tants- Gengo' s group uses the Multiple Sleep Latency Test

effect of a new drug against a placebo," Gengo says. "You

(MSLT) and psychomotor assessments during a regime of

find a statistical difference, but what is the functional

scheduled naps for subjects taking regular doses of the

significance or relevance of the difference?"

medication (or placebo).

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'
tial for those types of
resources to grow.
We are considered a
resource library, regionally and nationally, and we provide
materials to other libraries for a fee. The
fees actually cover
the cost of those services and even generate a little bit of
extra income that we
can use to supplement other services
and resources.
"T he last initial
impression I'd like to
mention is the very
strong support from
the faculty community here on campus ....._....__ _ _ _....;..J

From bound volumes to HUBNET
GARY BYRD REFLECTS ON HIS FIRST YEAR AS
DIRECTOR OF US'S HEALTH SCIENCES LIBRARY

ary D. Byrd, director of the University at Buffalo's Health Sciences
Library since january 1995 , came
to Buffalo after nearly 12 years at
the Health Sciences Library at the
University of orth Carolina at
Chapel Hill as Associate Director (198387) and Assistant Director for Finance,
Planning, and Research (1987-94). He
completed his doctorate in library science at that university in 1994.
His first year at the helm ofUB's H L
has confirmed his initial positive impressions.
"First, this is a beautiful facility-it's
one of the nicest facilities on the orth or
outh Campus, in my estimation.
This was the original
Lockwood Library at the
old private UB, and the
main reading roomthe Austin Flint Reading Room-is a
showplace for both
campuses.
"We have a very
knowledgeable, service-oriented
staff.
They've gotten well-deserved service excellence awards
from the university administration;
they're well respected on campus and in
the region and nationally , and that was
one of the real attractions to me in this
job-being able to work with such a
highly motivated , competent staff.
"Another obvious thing that impressed me right away was the information resources that have been gathered
and made available under the heading of
HUB ET [Hospital and University at
Buffalo library resource ETwork].

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HUB ET is an array of bibliographic
and full-text electronic information resources that have been gathered and
made accessible over a wide-area network, so that health sciences faculty ,
students, and practitioners at the university and its affiliated teaching hospitals , as well as at other practice and
teaching sites throughout Western ew
York, can easily log on to this array of
databases and search the medical literature-including full texts of many journals-and get an impressive amount of
other information resources at their fingertips. This is a wonderful array of
for this library, and the Friends of the
information resources, and a model for
Library organization that we have. Also,
the way in which electronic inforI sensed in meetings with the deans ,
mation resources can and
before l took this job, that they were also
should be provided in
very supportive of this library and that
this kind of a setting.
they were eager to support our resources
"The gem of our
and services. One demonstration of their
collection is our
commitment is that this year the deans
History ofMedicine
all agreed to help support the ongoing
Collection, which I
costs of the HUB NET system from their
would call a worldown budget, as well as from the hospiclass history of
tals' and the library budget, so that's a
medicine collection.
new source of support."
It includes not only loByrd first became interested in inforcal medical history, but a
mation resource management through
very impressive assortment
his work for Ship Hope in Tunisia in the
of other historical materials illustrating
late 1960s, when he was in the Peace
the history of medicine and the health
Corps. The mission of Ship Hope , a
sciences. The School of Medicine is the
volunteer project of American health
oldest part of the university , and the
professionals who refitted a World War
sesquicentennial will be drawing pretty
ll vessel as a floating hospital , was to
significantly from those collections.
dock at ports of developing countries
"I was also impressed by the potenfor nine months to a year at a time,
tial to strengthen resources in the seroffering modern medical services and
vices despite budget constraints. Some
training for local doctors. Byrd credits
of our services actually generate income
his experience as a volunteer assisting
that helps us support those and other
the ship's chief of staff with inspiring
services, and I think we have the potenhim to pursue a fellowship in biomedi-

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future , we may not
have a separate circulation department, for instance.
We may be providing reference services in new locations and in different ways, and providing an increased
array of reference
services , such as
more in-depth consulting."
Byrd hopes to
make better use of
limited resources
by restructuring the
HSL and granting
greater flexibility to
the staff. He praises
the experience and
HSL director Gary Byrd in the library's Austin Flint Reading Room.
dedication of not
cal library science at the University of only the library's faculty and profesMinnesota in Minneapolis.
sional employees but also the support
One of Byrd's first projects upon ar- staff and clerical workers, and he pledges
riving at UB was to work with his staff to to use these most valuable human recreate a vision statement of the long- sources more effectively: "We've got
term goals and guiding principles of the many people with many years of service
HSL. He would like to see the library to the university and to this library, and
become more flexible and better able to my feeling is that we need to find ways
respond to the health information needs to use their energy and creativity, and
of both local and remote users.
give them opportunities to use their
"This library has had a fairly tradi- skills in new ways."
tional organizational structure," he says,
Byrd notes that the evolution of per"with public service units and technical sonal computers and the Internet has
services units-cataloging, acquisitions , changed the way information resources
and management of all our serial collec- are managed. "An increasing number of
tions. ow we're in the process of re- our resources are available electronistructuring, somewhat. We're consoli- cally from computer terminals all over
dating our technical services units into a campus, and at remote sites in our affilisingle collection management services ated hospitals and practice sites all over
unit, and we're looking at possible new Western ew York, and even from
models for organizing our public service people's homes. We have an increasing
units and consolidating the way in which need for telephone support for remote
we provide services from all of our public users. We need to use staff more flexibly
service points-the places where the in ways that will allow them to go out
public can approach the staff and ask for and work directly with users in their
help or information, such as the circula- offices, or in their labs, or in classrooms.
tion desk, or the reference desk. In the We need to strengthen the library's in-

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ternal computer and telecommunications infrastructure and its links to campus, regional, and worldwide electronic
information networks.
"The library is organized in many
ways like an academic department: We
have library faculty as well as professional and support staff. Our library
faculty not only provide reference and
other services, but they help instruct
students, faculty, and staff on the effective use of information resources. And
not only do we provide classes that we
teach here in the library, but our faculty
also go out and serve as guest lecturers
and instructors in courses that are taught
by other faculty.
"I personally think there will be an
increasing need in the future for courses
that are actually taught by library faculty as part of the regular university
curriculum. In some areas of the health
sciences, especially, courses may really
be needed on how best to manage information resources; how to use appropriate computer hardware and software to
manage information, to browse the
Internet, to use library resources, to
understand the concept of effective
search strategies, to understand how to
use controlled vocabularies or Boolian
logic or other strategies that make for
effective use of the literature.
"We still have a ways to go to
strengthen and build on the resources
that we have, but I think that we've
gotten a strong commitment from everyone to work together to help make
that possible. We don't have any magic
bullets. I think the ammunition that we
do have is our ability to demonstrate the
value of the resources and services that
we provide to the community, and then
work collaboratively with the other parts
of the university and with our affiliated
hospitals to pull together the resources
to turn those things into reality." +
-LUCY

e

GARDNER

CARSON

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BARANSKI
ADVERTISING

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your company image to the
public ... and to prospective
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Baranski Advertising, we are
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ew York, publications where
your advertising message is sure
to reach a quality audience.

Medical students enjoy new lounge
tudents in the School of Medicine and Biomedical Sciences
have a new place to prop up their feet, thanks to the
generosity of the Medical Alumni Association.
Over the past two years the alumni group has donated approximately $4,000 to refurbish a
former conference room in Cary Hall, which recently was outfitted with couches and a coffee table; a
conference table; electronic equipment, including a television and VCR, a photocopier, and a microwave;
a foosball table; and artwork.
The purpose was to make the free time medical students have at lunch and between classes more

CALL US TODAY

enjoyable, according to Neha Sangwan, president of Medical School Polity.

(716) 645·6933

"We wanted a little more of a social place than a study area. We wanted to get students to start
to interact and to get to know people in different years, and to give them something to do," she said.
"We greatly appreciate all the efforts and support of

MICHAEL J. BARANSKI

the Medical Alumni Association because it's helped to

Marketing Representative

bridge the gap between the first· and second·year
students. This has provided a really comfortable

P.S. We did this book!

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atmosphere so we can get to know each other."

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::» Percent and number of graduates
from 1989-91 entering primary-care
specialties-45th and 23rd, respectively;
first among SU Y medical schools. (UB's
total graduates for the three years, at
4 3 7, is larger than that of 70 percent of
U.S. medical schools, a factor which
lowers its percentage ranking compared
"All medical schools share the broad to schools with fewer graduates. Also,
and essential missions of education, re- the rankings in this category do not
search, and patient care," Cohen said. reflect the success of the medical school's
"However, within this context, individual Primary Care Initiative, begun in 1990,
schools have different priorities and goals. which has raised the percentage of UB
Because of this, a single ranking of medi- graduates entering primary care from
cal schools is inappropriate and mislead- an average of 28 percent for 1989-91 to
ing. The Institutional Goals Ranking 40 percent for the class of 1995. [In the
Report is designed to provide medical AAMC survey, schools with 40 percent
schools and the public with several scales of their 1989-91 graduates entering primary-care specialties
by which they can mark
ranked 5th.])
an institution's achievements in various areas."
::» Percent and numUB received its highest
ber of 1995 graduates
marks in the category of
planning to practice inpercent and number of
state-58th and 42nd,
1981-90 graduates who
respectively; fourth
are faculty, ranking 14th
among SU Y schools in
and 18th, respectively.
percent, second in numAmongSU Yschools, UB
bers.
ranked first in percentage
::» Federal research
and second in numbers.
grants and contracts in
aughton said UB's
1993-94-67th overall;
second among SUNY
high ranking in this category reflects the emphaschools.
sis the school's faculty John P. Naughton, M.D.
Naughton noted that
places on teaching and education in its UB's listing doesn't include research fundbasic-science and clinical-training pro- ing administered by its affiliated cancer
grams.
research center, Roswell Park Cancer
"Our graduates learn that as faculty Institute. Research funds attributable to
members, they can play an important UB faculty working at Roswell Park torole in guiding the future of students taled $21,771,842. If these funds had
and residents, can influence the future been included with those administered
of medicine, and can enrich their per- directly by SU Y, UB's ranking would
sonal and professional lives," he said.
have been 36th instead of 67th.
UB's rankings in the remaining cataughton said the report, prepared
egories were:
since 1990 but released to the public for
::»Percent and number of thefirsttimeinl995, isusefulforgaugunderrepresented minority graduates ing the medical school's progress in
during 1990-94-27th and 23rd, re- important areas and for judging its perspectively; second in both listings among formance in comparison to medical
SU Y schools.
schools of similar size and scope. +

UB ranks high as contributor to
medical school faculties
he University at Buffalo School of
Medicine and Biomedical Sciences
received high marks from the Association of American Medical
Colleges (AAMC) in its 1995 Institutional Goals Ranking Report,
released in late December.
UB received its highest ranking14th among the nation's 125 U.S. medical schools-in the category of percent
of graduates who are on the faculty of a
medical school. UB was one of only two
public universities in the top 15.
In the remaining categories, UB
placed in the top fifth to the top half in
all listings but one, and was first or
second among the State University of
ew York's four medical centers in all
listings but one.
john P. aughton, M.D., UB vice
president for clinical affairs and dean of
the medical school, said he was very
gratified by the results of the report.
"These rankings indicate we have
been able to achieve a successful balance between academic excellence and
clinical relevance ," he noted.
The AAM C report assessed the success
of the nation's medical schools in meeting
five goals considered important in today's
medical climate: graduates entering primary-care specialties; graduates planning
to practice in-state; graduates who are
medical-school faculty; graduates who are
underrepresented minorities; and total
research grants and contracts.
jordanj. Cohen, M.D., AAMC president, said the report is not intended to
determine which medical school is
"best," but should be used by medical
schools and the public to evaluate these
institutions in selected categories.

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sociation of the History of Medicine in
Buffalo in honor of the medical school
sesquicentennial (May 9-12 , 1996)
&gt;- Bestowal of honorary degrees at
commencement in 1996 and 1997
&gt;- Symposium on Epidemiology and
Preventive Medicine (September 20-21 ,

Exhibits to highlight medical
school's sesquicentennial year

1996)

three-day national symposium on
Ethics and Values in Medicine, the
national meeting of the American
Association of the History of Medicine, and a special opera performance will highlight the celebration of the 150th birthday of the University at Buffalo School of Medicine and
Biomedical Sciences.
Founded in 1846, the medical school
was the first component of what is now
the niversityatBuffalo, which is marking its sesquicentennial during an 18month period in 1996 and 1997.
A 24-member commiuee composed
of physicians, historians , archivists, scientists, and representatives from UB's
teaching hospitals has spent the past
three years planning special events to
commemorate the medical school's century-and-a-half record of excellence in
education, research, and service.
Ronald E. Ball, M.D., clinical associate professor of gynecology and obstetrics, and Harold Brody, M.D., Ph.D.,

SU Y Distinguished Teaching Professor
in the Department of Anatomy and Cell
Biology, co-chair the committee. joyce
Vana , Ph.D., clinical assistant professor
of social and preventive medicine, serves
as its coordinator and liaison to the dean
of the medical school.
For residents of Western ew York,
the most visible sign of the medical
school's sesquicentennial celebration
will appear in january 1996, when 50
blue-and-gold commemorative banners
will be installed along Main Street and
Bailey Avenue on UB's South Campus,
home of the medical school.
The celebration will begin officially
on February 22 , 1996-University
Day-with the dedication of the medical chool's new $33 million biomedical
research building, the awarding of an
honorary degree, and the presentation
of the 1996 D.W. Harrington Lecture.
Events planned for 1996 and 1997
include:
&gt;- Publication of a pictorial history
of the medical
school (February 1996)

&gt;- ational symposium on Ethics
and Values in Medicine (November 1416, 1996)

&gt;- One-day scientific colloquium
and bestowal of an honorary degree
(February 1997)

&gt;- Special performance by the Greater
Buffalo Opera Company (Februwy 1997)
&gt;- Special exhibits at the Buffalo
and Erie County Historical Society and
the medical school's affiliated teaching
hospitals +

"How We Die"Author to Deliver
Stockton-Kimball Lecture in May
Dr. Sherwin B. Nuland, the author of National
Book Award winner How We Die, will deliver the
annual Stockton·Kimball Lecture at Spring Clinical
Day on May 11. The tiNe of his talk will be "Death,
the Doctor, and Hope." Nuland earned his M.D.
from Yale University in 1955 and trained at Yale
in general, cardiothoracic, and cardiovascular sur·

&gt;-Mounting
of memorial
plaques marking the three
original medical
school
buildings in
downtown
Buffalo (May

gery. Anoted speaker on medical topics, he has
also written monographs on historical figures in
medicine, such as Hippocrates and Napoleon's
surgeon, Dominique Jean Larrey. In his 1994
book, How We Die: Reflections on Life's Final
Chapter, he discusses haw modern doctors too

1996)

often try desperately to save life, abandoning an

&gt;ational
meeting of the
American As-

older mission to help people die with dignity.

Sesqui(entennial banners now festoon the medi(al S(hool (ampus.

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UB medical faculty appointed to national panels

l

59th Annual Spring Clinical Day

Cedric M. Smith, M.D., professor of pharmacology and toxi-

Saturday, May 11, 1996
Buffalo Marriott

cology at the University at Buffalo, has been appointed to
a five-year term on the Expert Advisory Panel on Drug
Information Science of the United States Pharmacopeia
(USP) . The USP, founded in 1820, is a non-profit organization responsible for establishing public standards of
strength, quality, purity, packaging, and labeling for drugs,
medicines, and other healthcare devices and services. The
standards are published in the USP- ational Formulary
and are enforced by the U.S. Food and Drug Administration.
The Expert Advisory Panel on Drug Information Science will be concerned primarily with expanding the USP
drug and therapeutic-information database, which recently combined with the AMA Drug Evaluations database.
Germaine Buck, Ph.D., associate professor of social and
preventive medicine at the University at Buffalo, has been
appointed to a three-year term on the ational Research
Council's ( RC) Committee on Toxicology.
The Committee on Toxicology, a component of the
RC's Commission on Life Sciences, provides expert
advice to government agencies on a broad spectrum of
toxicologic issues and problems.
Buck has won national recognition for her epidemiologic
research in human reproduction and fetal and early-childhood health. +

Medical Alumni Association
State University of ew Yorh at Buffalo
Continuing Medical Education

End of Life/Quality of Death
Death and the dying process hove traditionally been ignored by the treatment· and technologyoriented medical profession. Medical schools hove only recently begun to offer any curriculum
in palliative medicine or death and dying.
For many physicians the death of opatient is seen as opersonal failure. As oresult, dying
patients and their families ohen feel shunned by and distanced from the physician at this
critical moment. The advent of odvonced-&lt;ore directives and heolthcore proxies has mode
issues of dying o necessary topic for discussion between physician and patient.
The objective of this conference is to help physicians become more comfortable with
death and thereby be better equipped to help patients and their families through the dying
process.
Participants will be exposed to the basic concepts of palliative medicine, learn about end·
of·life core resources in Western New York, and discover strategies for easing the transition
from curative to palliative core.

Principal Presentations
"Dying Healed-The Nature of Care at the End of Life"
Robert A. Milch, M.D. '68

"Delivering Bad News with Compassion and Hope"
Judith Skretny, M.A.

"Confronting Difficulr Emotional and Ethical Issues in the Care of the Dying"
(panel discussion with case presentations)
Martin Brecher, M.D. , )ach P. Freer, M.D., Ross G. Hewitt, M.D.,
Robert A. Milch, M.D.

"Death, the Doctor, and Hope"
Stockton-Kimball Memorial Lecture
Sherwin, uland, M.D., F.A.C.S., author of How We Die

The 1996 Spring Clinical Day will begin with registration at 7:30a.m. and welcoming remarks
at 8:00 and conclude with the annual Medical Alumni Luncheon at noon, followed by the
Stockton·Kimboll Memorial Lecture.

UB chemistry professor Philip Coppens (right)was honored by the HauptmanWoodward Medical Research Institute with its first David Harker Award for
outstanding contributions to the field of crystallography. Coppens received
the prize at the dinner commemorating the 1Oth anniversary of the
awarding of the Nobel Prize to Herbert Hauptman (left), institute president
and UB research professor of computer science.

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The Accreditation Counci l for Continuing Medical Education designates this program for up to 4 hours of Catcgor) I credit toward the
Physician's Recognition Award of the American Medical Association.
This program has been reviewed and is acceptable for 4 prescribed hours
by the American Academy of Family Physicians.

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�Afriend called him "idealistic in apractical way"
DR. ROSWELL PARK WAS A PIONEERING CANCER RESEARCHER AND " LIVING
ENCYCLOPEDIA" WHOSE LEGACY LIVES ON IN TWO GREAT LAKES CITIES

country, and was led by a well-known and well-respected
his many achievements, founding the world's
medical faculty. Park also relished the challenge of establishfirst cancer research institute in Buffalo in 1898
ing
himself in a new city-and he was challenged. A piece
is the one for which Dr. Roswell Park is probably
published in the Buffalo Medicaljoumal commented on the
best remembered. Rechristened the Roswell Park
acquisition of Park by the university, questioning why a
Memorial Institute in 1946 and known today as
Buffalonian couldn't be found to fill the vacancy: "We fail to
the Roswell Park Cancer Institute , this vital
research and educational center was born out of Park's
ascertain , after repeated inquiries in surgical circles, that the
conviction that the increasing incidence of cancer around
new appointee brings to this responsible position any ex tenthe turn of the century called for more immediate and
sive experience or reputation. " It wasn't long, however,
constant attention. Although the severity of his claims was
before Park's indisputable character and aptitude won over
the disgruntled columnist and the two achieved a friendly
originally contested, he even went so far as to predict in 1904
that cancer deaths would one day outnumber deaths from
relationship.
tuberculosis. Park's concern about the increase of cancer
In 1891, Rush Medical College tried to recapture Park by
cases was as humane as it was scientific: He realized
offering him the post of chairmanship of surgery-a
that both professional and public attitudes toward
tempting invitation that would have been an errorcancer patients during the nineteenth century
mous promotion for Park. But a local group of
were harsh, primitive, and counterproductive to
influential medical professionals and public infinding a cure for the disease.
dividuals coordinated a campaign to convince
Park to stay in Buffalo, countering the Chicago
Roswell Park was born in 1852 in Pomfret,
offer with an offer of its own: Would Park be
Connecticut, into the ninth generation of a
prominent family that had arrived in America
interested in a third building for the medical
on the Mayflower (and had entered England
school, on High Street, to be constructed to
Park's specifications? Yes , Park would.
with William the Conqueror). The first generation of Parks to venture from the East Coast,
Park worked diligently and, aided by his
many government and professional contacts,
Roswell's family relocated to the Midwest when his
father founded Racine College in Racine , Wislaunched an ambitious campaign to secure canconsin. After completing his B.A. and M.A. lr-=o=--R-=
R-o_s _w_ E_L_L---:P:-A
- R- K
--,1 cer-research funding. In 1898, he and Edward
degrees at Racine , Roswell Park earned his
H. Butler Sr. , publisher of the Buffalo Evening
M.D. at orthwestern University in 1876. After three years
ews, won the world's first public-fund appropriation for
cancer study. This 7,500 from the ew York State legislaas adjunct professor of anatomy at his alma mater, Park left
to pursue his medical studies in Germany, France, and
ture helped establish the ew York State Pathological LaboAustria. Indicative of his growing reputation , he was apratory of the University of Buffalo, the first lab in the world
pointed lecturer of surgery at Chicago's Rush Medical Coldevoted exclusively to the full-time study of cancer. Within
lege and an attending surgeon at Chicago's Michael Reese
two years , the three small rooms the medical school had
Hospital while still in Europe. Park did soon move to
designated for laboratory use could no longer meet the
Chicago, and it was there that he began what was to be a long
demands of Park's research. Public donations and private
and successful medical career in two Great Lakes cities.
giving from Mrs. William Gratwick made it possible for land
In 1883 Park left Chicago for the medical department at
to be purchased for construction of the Gratwick Research
the niversity of Buffalo, where he became professor of
Laboratory at the University of Buffalo. Completed in 1901,
surgery and later joined the new dentistry department. He
it was , this time, the first lab in the world to be built and
also worked as a surgeon at the Buffalo General Hospital.
equipped solely for cancer research.
Several things about the niversity of Buffalo appealed to
Although by 1904 a ew York State grant annually
Park: It had one of the oldest and best medical schools in the
allotted the lab 15,000 for maintenance, it was not a state

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�sidered among his most influential publications are the
facility; that is , until19ll-thanks to the concerted efforts
Mutter Lectures on Surgery, given in Philadelphia; the Lecof Park, along with the support of government officials and
tures on Surgical Pathology; the Epitome of the History of
the public. It was renamed the ew York State Institute for
Medicine; Surgery by American Authors; and the Practice of
the Study of Malignant Diseases, a title it retained until1946,
Surgery, deemed
when it was reby many his finest
named after its iniwork. As a musitiator.
cian
, he was reFor thirty-one
ported to be highly
years until his
skilled; he prideath, Park served
vately published
as a UB professor
his musical pieces
of surgery and Bufin a collection he
falo
General
modestly titled A
Hospital's chief
Little Music.
surgeon. Both inIt is not surprisstitutions would
ing that one of
feel Park's influPark's admirers
ence for another
called him a "livthirty-one years
ing encyclopedia. "
after his demise, as
"When
others
each was led by his
sought
rest
in novformer students.
elty, gaiety, and
Park's medical
change," the friend
expertise and reexplained , "Park
assuring profescould be found
sionalism earned Roswell Park (lacing the camera) operates before medical students and faculty, c. 1895-98.
storing his splenhim the presidid mind with
dency of the American Surgical Society, as well as American
fresh material. "
membership in the International Congress of Surgeons. As
one ofBuffalo's most trusted and well-known surgeons, Park
Rarely did Park
slow down, even
was appointed medical director of the Pan-American ExpoFrom its meoger three-room beginning in 1898, the
as he got older
sition of 1901, held in the city, and he was among the team
Roswell Pork Concer Institute today spans twenty-five
and intermitof physicians who attempted without success to save the life
acres in downtown Buffalo, maintains osatellite
tentlyill. Uncharof assassinated President William McKinley.
acteristically, he
research facility in Springville, New York, ond includes
Park's achievements in medicine alone would guarantee
made
plans
to
go
him a place among Buffalo's most successful citizens; howamong its fifteen buildings in Buffalo o 218-bed
away and simply
ever, he did not rest at the borders of his own profession. As
hospital. The institute is currently undergoing o $241
relax in 1914, but
a dedicated member ofUB's University Council, Park fought
million renovation ond modernization of its facilities,
died two days
for the expansion of the university into the arts and sciences,
slated to be completed in 1998, its centennial year.
later on February
prompting one colleague to describe him as "idealistic in a
Cancer survival rates hove increased dramatically
15-almost cerpractical way. " His desire to be involved in creating a comfrom Pork's day, when being diagnosed with cancer
tainly of heart
plete university led to the establishment of the College of
was virtually equivalent to odeath sentence. Only one
failure-emArts and Sciences shortly before his death-and his son Dr.
in five people survived the disease in the 1930s, one
bodying perhaps
julian Park would become its first dean, a position he would
in four in the 1940s, and one in three oscore later.
his favorite and
hold for forty years. In men's social circles, Park was called
Equally impressive is the fact that survival rates for
often-quoted
a "notorious mixer"; he held the presidencies of both the
aphorism: "The
those stricken with leukemia tripled between 19 50
Buffalo Club and the Liberal Club. As a scholar, he wrote 167
future reserves
textbooks , articles , and monographs dealing not only with
and 19 60- thanks, in no small port, to the
for us repose
medicine, but also with thanatology, student life in the early
pioneering efforts of Dr. Roswell Pork.
enough. " +
Middle Ages, and sixteenth-century Italian philosophy. Con-

Roswell Park'sButfalo Legacy

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Humor©

gotten sick and they've called out over
the P .A. for a doctor. There I am, resting
comfortably in the middle seat with my
knees in my eyes (I believe they call it
the "chiropractor position"), when I hear
the announcement: "If there is a doctor
ACTUALLY , THE FIRST TIME I ANSWERED A CALL FOR
on board, please make yourself known
HELP , THIS PAST SUMMER , IT WAS A S ICK CHILD
to the flight attendant."
My first thought is, maybe they are
looking
for a date, or they have an Amway
111•111 his summer I made the deci- (Stamford, to be exact, but I still prefer
on the side and are looking to
business
sion to move from the prom- to think of it as the ew York Metro
ised land (California) to the area). Things are different here: obody bring doctors fleeing managed care into
homeland ( ew York Metro has a sense of humor. For instance, the their group. The scary thing is, at this
area). Perhaps it was the trickle- woman at the rental agency's name was point I might even be interested-espedown effect of managed care. I Anita Head. When I laughingly asked if cially if I begin as a Double-Diamond
believe I reached my low point that was her real name, she retorted, Attending.
Sometimes I am reluctant to respond
when I was moonlighting in an occupa- "What's so funny about that?" I thought
to
these
mid-air announcements. What
tional medicine clinic (despite my train- to myself, "You not only need a head ,
if
it's
a
situation
I can't handle? This
ing in pediatrics) and examining an but you need a sense of humor. "
When I moved back East I needed to time, however, I literally jumped at the
employee of Federal Express. The patient, a graduate student in finance , was fly one way, and there was only one opportunity, since l was trapped in the
explaining the wonderful benefits pack- airline that would sell a one-way ticket. middle seat between two guys named
Barry who were taking turns
age offered to Fed Ex employpicking their teeth while disees who work as few as 20
cussing
their favorite episode
hours a week-a benefits
of
the
Carney
Wilson talk
package that includes free
I CHOSE THE SAME AIRLINE WHEN
show ("Good-Samaritan Docflights to anywhere they fly.
RETURNED TO CALIFORNIA FOR
tors Who Get Sued While
The only catch, he noted, i
Helping
Transsexual Patients
that you have to be willing to
VACATION DURING CHRISTMAS BREAK ,
with
Kleinfelters").
You can
sit in the "jump seat." ow,
ON
A
"
MANAGED-CARE
VISA"
(YOU
see
why
I
welcomed
this opI'm not even sure what a jump
portunity
to
get
up
and
seat is, but I figure any seat
KNOW , JUST ONE HOUR AND NOT A
"work.
"
Anything
to
escape
that includes the word
the "dueling teethpickers."
"jump" sounds like it has
MINUTE LONGER ).
Another reason l am usumore room than the average
ally reluctant to get up and
coach cage-! mean seat.
assist in these situations is, I
I even went so far as to jot
down the name of the person in charge I don't want to name the airline, but let am a pediatrician. It's not very often that
of personnel at FedEx (I still have her me just say it sounds like "terror air" kids get sick on planes, although l have
number, in ca e l ever decide to move and leave it at that. lt is also the only considered supplementing my income
back to California). Then it occurred to airline that has no frequent-flyer pro- by offering an impromptu pharmacy
me that I may be overqualified: After all, gram (probably because it doesn't have service specializing in Benadryl and other
I've written a book, and I am a pediatri- any frequent flyers-except me, that benign sedatives for children in the back
cian ... maybe I could specialize in lift- is). I chose the same airline when l of the plane (I could make a killing on
ing crates filled with children's books? returned to California for vacation dur- flights to Orlando and Anaheim).
Actually, the first time I answered a
As I said, that wa the low point. o ing Christmas break, on a "managedcall
for help, this past summer, it was a
care
visa"
(you
know,
just
one
hour
and
now l find myself in Connecticut, in the
child-one who had had corrective
sick
middle of the "Blizzard of '96"-not not a minute longer).
surgery
for cyanotic heart disease two
For some reason, every time l have
unlike the Blizzard of '77 in Buffalo
('nuff said). I am living in Connecticut flown this airline (twice) someone has years earlier. A little oxygen did the

...adoctor on board?"

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�Stu

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trick, and I was an instant hero. The
second time it was a very un-pediatric
problem: a 38-year-old with tingling
and numbness down his arms and legs.
He was only a couple of years older than
me, so 1 knew there was no way he could

in the back, I had to prove I was a doctor.
Like somebody is going to try to take on
that responsibility just to impress people:
"Stand back! 1 am a doctor ... okay, I
have a Ph.D. in political science, but you
did ask for a doctor. "

be suffering from a stroke or heart attack (could he?!). I quickly asked the
usual questions: What did you eat? Do
you have a past medical history? Taking
any meds' (Are you a lawyer?)
ow, believe it or not, before they
would even let me touch this guy or
open up the bag of equipment they keep

As soon as I got over there and identified myself as an M.D., you could see the
guy felt better right away, which just
goes to show the importance of touch in
medicine-and let's face it: touch is about
all you can do on a plane. There is no
CBC, no enzymes to measure, and no
pulse oximeter. The guy's blood pressure

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M.D.

and vitals were stable, and he improved
with a little reassurance, so I concluded
that he was most likely suffering from
hypoxia coupled with flu symptoms.
But just to be on the safe side, I
decided to radio an internist on the
ground, which meant that I got to
take a trip to the cockpit. When I got
there the pilot, co-pilot, and flight
engineer all turned around to talk to
me-and I'm thinking, "Who the hell
is flying the plane?!" Automatic pilot
or no automatic pilot, I want to tell
you it is unnerving in the extreme to
see these guys all looking backward
while the plane is moving forwardkind of like riding in a ewYork City
cab and having the driver climb into
the back seat to chat while the car is
going down Fifth Avenue at 45 miles
an hour. (Come to think of it, that's
probably not so unusual, ew York
City cabbies being what they are.)
Anyway, the pilot gave me his
card (first time that's happened
to me) and promised he would
put in a word for me so I could
get a free flight.
So wouldn't you know it? I'm
headed back to the East Coast from
California (trip number three on "Terror Air"), minding my own business,
and I hear that call for help on the P.A.
again. This time it's a 33-year-old woman
who has fainted in the back of the plane.
I get up to answer the call to duty and
the flight attendant says, " ot you
again," which is precisely what I was
thinking. So now I am three for three.
Well, by now I am even ready to
consider working for this airline instead of Federal Express, provided the
benefits package is better. In these days
of economic uncertainty, you have to
find work wherever you can- even on
cross-country flights. +
Stu Silverstein, M.D., president of Standup Medicine Seminars of Son
Francisco, California, and Stamford, Connecticut, lectures nationwide on
humor in medicine.

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lEI
Promoting prevention at the CDC

JAMES MARKS '73 IS THE NEW DIRECTOR OF THE NATIONAL CENTER FOR
CHRONIC DISEASE PREVENTION AND HEALTH PROMOTION

same pragmatic approach to the agency's long list of target issues:
eeing one patient at a time isn't enough for James S.
cancer, diabetes, heart disease, adolescent behavior, nutrition,
Marks, M.D. '73: He prefers to take them in batches of
physical exercise, community health, oral health, teen pregnancy,
hundreds of thousands.
family planning, reproductive health, infant mortality, and smokMarks is the new director of the ational Center for
ing. Some current projects include monitoring mammogram rates,
Chronic Disease Prevention and Health Promotion, a
expanding state cancer registries , and helping redesign
principal unit of the federal Centers for Disease Control
school
health curricula to emphasize prevention. The agency also
and Prevention.
puts out several hundred publications a year, including its famous
"People don't realize that chronic disease causes 70 perSurgeon General's Report on Tobacco, an annual summary of
cent of the deaths in the United States and 60 percent of the
research on smoking and health.
healthcare costs. We're having trouble paying for it already.
"Our responsibility is to see that the findings of research
That means either we are going to have to curtail care, or we'll
about prevention are disseminated widely so that people
have to reduce the incidence of these problems through
know what to do to avoid chronic disease," Marks says.
prevention. And we believe prevention is the only humane
That entails distributing most of the agency's $400 milsolution," Marks says.
lion budget in grants to state health departments , universiMarks was appointed director of the 550-person agency
ties, schools, and other organizations to fund education,
by CDCP Director David Satcher in June 1995, but long
monitoring, and research programs.
before that he had made a name for himself as an outspoken
Marks grew up in Alden , near Buffalo, and majored in
advocate of preventive health. His numerous publications
psychology as an undergraduate at Williams College in
include editorials for the journal of the American Medical
Massachusetts. He earned his M.D. from UB in 1973 (where
Association in which he applies science to social problems
his father, Eugene, had earned his M.D. in 1946), and
to come up with non-ideological, although not necessarily
completed his internship and resinon-controversial, solutions.
dency in pediatrics at the UniverIn a 1985 JAMA commentary,
" THAT' S WHEN HABITS BEGIN , IN
sity of California at San Francisco,
he recommended creating a desigADOLESCENCE . WE' VE GOT TO SHOW
where he also worked in a Planned
nation called "fetal tobacco synTHEM THAT GOOD HEALTH HABITS
Parenthood Teen Clinic.
drome" to call attention to the
"I realized while I was pracARE TO THEIR OWN BENEFIT , AND
well-known correlations between
ticing
in San Francisco that the
smoking and low birth weight and
THAT THEY' RE NOT JUST
problems
I was seeing were
pregnancy complications. An ediACCEPTABLE , BUT COOL. "
broader
problems
than just the
torial in 1987 advocated commuclinical ones," he says. Dispensnity-based sex education that
ing antibiotics and vaccinations did nothing to remedy the
would teach teens not only how to say "no " to sex-but also
poor nutrition , teen motherhood, and other societal probhow to protect themselves if they said "yes."
lems he saw day after day. "l got interested in the broader
"Sexual messages pervade our lives-at home, in schools,
community issues. "
in media, in shopping centers, on airplanes , and even in
He was hired by the Centers for Disease Control as an
physicians' offices," began another JAMA editorial urging
Epidemic
Intelligence Service Officer in Ohio. On his
universal sex education. His next sentence no doubt surfirst day at work, he was sent to Pennsylvania to help
prised readers expecting disapproval of our sex-obsessed
investigate what would become known as Legionnaires'
society: "Rightly so, since being sexual is part of being
Disease. "It was tremendously exciting, my first day on
human."
the job! " Marks remembers. He also investigated outAs head of the preventive health agency, Marks is applying the

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.

•

breaks of measles
and diarrhea , as well
as complications
from the swine flu
vaccine, and was
sent to Hawaii to
monitor an outbreak
of German measles
in adults.
With a growing
conviction of the importance of epidemiology and public
health, Marks left the
CDC to earn a
master's d eg re e in
public health from
Yale University, winning a Robert Wood
Johnson Clinical
Scholars fellowship.
Toward the end of his
studies, Marks served James Marks, M.D. '73, on the Centers for Disease Control and Prevention campus near Atlanta, Georgia.
six
months
as
"It's the leading cause of preventable mortality in this
Connecticut's acting state epidemiologist. He also returned
country," he says. "The tobacco companies have to deny
to pediatric practice. "I just wasn't sure l wanted to stop
what science is most clear on-the links between toseeing patients," he remembers.
bacco and cancer and heart disease-every time we
Marks rejoined the CDC in 1981. Since then, he has held
publish
the Surgeon General's Report on Tobacco. They
a number of science policy appointments in various departhave
to
have 3,000 children start smoking every day
ments, including the Birth Defects Branch and the utrition
because
400,000
of their best customers die each year
Division of the Epidemiology and Research Branch. Most
and 600,000 quit."
recently, he served for four years as the director of the
However, the same issue has provided the most encourDivision of Reproductive Health, a subunit of the agency he
aging example of the success of public health education,
currently heads. Marks also teaches at Emory University
he says.
School of Public Health and has served as a consultant to the
"When the Surgeon General's Report of 1964 came out,
World Bank and the World Health Organization.
which was the first to publicly state the risk of smoking,
One of his goals for his agency in the coming years is to try
nearly 50 percent of the adult population was smoking. Now
harder to reach adolescents with the messages of preventive
it's
down to the low 20s. That's an incredible change and an
health. "That's when habits begin, in adolescence. We've got
incredible success."
to show them that good health habits are to their own benefit,
Marks, 47, lives in Atlanta with his wife, Judy (a 1968
and that they're not just acceptable, but cool."
graduate of UB, where she was named "Outstanding FreshHe also hopes to begin attacking Americans' sedentary
man Woman" and served as president of the Honor Society),
way of life by promoting physical exercise, and to continue
and his 16-year-old son, Adam. His 19-year-old daughter,
to monitor the health problems of the uninsured. "We are the
Amy, is at college, where she is tentatively pre-med. Alonly industrialized country that doesn't cover our entire
though he has enjoyed living in Atlanta for many years,
population. When we're designing programs for HMOs and
Marks retains fond memories of his alma mater.
insurers , we can't lose sight of the fact that they don't cover
"l still miss the snow and the Bills," he says. +
20 percent of the population."
One topic that never fails to get Marks' juices flowing is
E
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tobacco.

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I

BERNARD 5 . STELL '36 , of un City,

Arizona, had l l slides-ofhis30 acceptedexhibited in imernational stereo photography exhibitions in 1994.

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MORTON A . STENCH EVER '56, of

Merler Island, Washington, continues to
teach and practice after resigning as chair of
the

niversit)' ofWashingwn's DepanmenL

of Obstetrics and Gynecology, a position he
held for 19 years. He also serves as associate
editor of Obstetrics and Gy necolog} , and has
coauthored Comprehensive Gynecology and
authored three books. He serves as treasurer
of the American Board of Obstetrics and

Thomas March '31 (arrow} at the 1966 reunion.

Gynecology, and is a member of the OB/
GY

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Residem Review Commiuee. He won

the 1995 Wyeth/Association of Professional
Gynecology and Obstetrics Annual Recog-

THOMAS A . MARCH '31 , of Tacoma, Washington, writes:

"As an ancient

alumnus of the medical school class of '31, I am perplexed at the silence of
other alumni from the class of'31. Perhaps it is because they feel 'too old.'

nition Award. He and his wife, Diane, recently celebrated their fortieth wedding anniversary, and enjoy their three children
and four grandchildren.

1

"A slwrt biography is perhaps indicated at this point:

9

WILLI AM

"After internship at Toledo Hospital (Ohio), I attempted general practice in

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E. ABRAMSON '60, of

Baltimore, Maryland, teaches aCME course
on substance-abuse education for primary
care physicians at Maryland-area hospitals,

four different locations in ew York State during the Depression of the '30s.

sponsored by the state medical society. He

"Economics forced me to tahe a staff appointment at Harlem Valley State
Hospital. Before I knew it I became eligible for Psychiatric Boards, after

continues his private psychiatry and addiction medicine practice at Sheppard PraLL
Hospital in Townson, Maryland.
I R V I N G 5 . KOLIN '61 , ofWinterPark,

postgraduate courses at Columbia University.

Florida, appeared as a guest of Ted David on

"After service overseas in the Army Air Force in 1942 (as a Lieutenant
Colonel; I resigned in 1945), I joined the staff of a VA Hospital. I became

a recent edition of C BC-TV's Money/inc LO
discuss the economic costs of substanceabuse disorders. The program was televised
nationally.

Hospital Director in VA, then continued in Veterans Administration as a
J OH N J . LAMAR JR . '63, of Salem,

director in two different locations. I retired in 1973 and had a private

ew jersey, is happy to announce that he

neuropsychiatric practice for about a year.

will be retiring in 1996. His youngest daughter, Danine M. LaMar, who married Glendon

"And now I am enjoying complete rest and retirement."

grade at Quinton Elementary School.

Lodge in 1994, will be teaching the third

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Orange, Connecticut, coedited with Hal

ange County Medical Society. He and his
wife, Colleen Mulligan (B.S.N . '79 ,

B. Jenson and 50 contributors a 1,600-

D'Youville) , are raising their two "big boys":

page text this summer entitled Pediatric

Todd , 8 , and Trevor, 3.

ROBERT 5 . BALTIMORE '68, of

SURF
THE
NET!
INTERNET
SOFTWARE
Many Titles!!

Infectious Diseases: Principles and Practice,
PABLO RODRiGUEZ '81 , ofWarwick,

published by Appleton and Lauge. He is
professor of pediatrics and epidemiology
at Yale University School of Medicine,
where

his

E-mail

address

PC Anywhere

Rhode Island, has been appointed associate
chief of OB/GY

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Hospital, the teaching hospital of Brown

is

University in Providence, Rhode Island. He

baltimorrs®maspo3. mas. yale.ed u.

has two children: Rafi, 6 , and Kika, -1-.

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ROSLYN

'86 , of

ROMANOWSKI

SUSAN A. BARDE '76, of Dayton,

Snyder,

Ohio, who is in private practice in allergy,

Western

wrote in to announce that her husband,

Millard Fillmore Ho pita!. She returned to

Christopher A. Barde '76, is chief of medi-

the area in 199-t, and assumed her latest

ew York, is thrilled to be back in
ew York doing heme/one at

cine at the Dayton VA Medical Center and

position after working one year at Buffalo

chair of gastroenterology at Wright State

General Hospital.

Can 't connect from home ll'ithout one'

INTERNAL STARTING AT
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niversity. They have two sons: Christian,
ANNA KRISTINA ELISE HART '89,

13, and Andrew, ll.

of Portsmouth, Virginia, has completed a

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second tour of duty as flight surgeon in the

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Florida, is chief of the Department of Plastic

cared for four squadrons and was head of

Surgery at Florida Hospital in Orlando and
a legislative committee member of the Or-

UNIVERSITY AT BUFFALO
S C HOOL OF M EDI C INE

150
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19

9

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nited States avy, most recently at AS
Whidbey Island, Washington, where she

WALTER SIEMIAN '80,ofWindermere,

CONTINUED ON PAGE 32

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6

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Prices slro•n• include a l et discoum for caslr paymems
Open .\fou. Tues. Fri 1/am-Spm. ned &amp; Thurs /lam-6pm
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Order your copy today for delivery in March 1996.

•r

rrt

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an r awlul'"

Pnl'•• ·hJtltooiuo,f(l'"lll

t 11&lt;•tll'

To place credit orders, call Walsworth Publishing Company at 1-800-369-2646, ext. 3339
A non-profit Umversity program for students faculty &amp; staff
The Commons • North Campus • (716) 645-3554 • Fox: 645-3884

6

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··························································

Why dtay home for
the holidayd?

I

J e nni fe r (Broman) Moman, who is practicing pediatrics in Beaver, Pennsylvania, and
is happily married to Dr. Moe Moman, a
dentist.
STEVEN P. HARRIS '91 ,ofPittsburgh, Pennsylvania, and his wife, jane,
announce the birth oftheirson teven Phillip
Jr., born September 1, 1995.

The front-wheel drive lnfiniti®130"'

MICHELLE PI ETZAK '92 , of Los An-

ing her residency at Children's Hospital of

Eln int~rt;&gt;r 11/0t'l' ,•pact;&gt;u,• than a Rolf,, Rove~
Si!..o· 5purlll. An ~.\-ceptulttal~v.tJm~mu,•
o/ ,•tandard lu.rw:v f~atur~.•. 1! /90-hp 1'6
mpaM~ o/out-acal~ratti'.tJ many !u.\·w:v Jl&lt;l:•.
Elntl o/ &lt;'tl/11".'~• th~ ,•tantlartl-,•ettin.tJ

Los Angeles. Currently, she is in the first

p~tj;&gt;rlllilll&lt;'~ anti ,•~r&lt;'lt"e

geles, California, married a fellow pediatrician, Derek Wong, in june 1995 after finish-

year of a fellowship in gastroenterology at
the

niversity of outhern California.

it;,,

t&gt;/ ln!i'niti.

S.J 79 mo. -12 IIIli. lea.•e

SO£11111'11

OBITUARY

DONALD HALL '41 , of Buffalo, died

Michelle Pietzak ' 92

january 7, 1996, after a brief illne s. He was
a past presidentofthe Medical School Alumni

the Aviation Medicine Department at the

Association. After service in the Army during World War !I and residency at Buffalo

hospital. During her two years at Whidbey
Island, she spent much of the time traveling

General Hospital and The Children's Hospi-

and participating in training exercises both

tal of Buffalo, Dr. Hall entered private prac-

in the area and as far away as the East Coast.

tice in obstetric and gynecology. He was an

he attained the distinction of being the first

assistant clinical profe sor at the medical

female assigned to two aircraft carriers, and
Achievement Medals for her accomplish-

Blood Services and the Deaconess Center of
Buffalo General Ho pita! Family Planning.

Pro_qram.

cine, working with several area medical or-

ments while on her assignment. She reports

ganizations, including American Red Cross

that she mi se the days of nying while a
night surgeon, but is enjoying being a resident in the world's largest and busiest naval

9

9

s

0

MICHELLE SKRETNY SUSCO '91 ,

Correction

of Clifton, Virginia, is a board-certified pediatrician practicing in a four-pediatrician

ELLEN GIAMPOLI '90 AND

group practice in Manassas, Virginia, after

CRAIG NARINS '90 were wed in

completing three years of residency training

Tarrytown, ewYork,onjune 10,1995.

at Children's National Medical Center in

Readers of the Autumn 1995 issue who

Washington, D.C. She and her hu band ,

arc friends of the couple have noted

joel, a CPA, who married in cptcmbcr
1995, will be living in their new home in

The editors regret their error.

~.\·t~n.•il'~

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-12 1110.

!ea,•e

SO tiown

I N F I N IT I

AUTOPLACE INFINITI
8129 MAIN ST., WILLIAMSVILLE

633-9585
East of Transit Rd.,
Near Eastern Hills Mall

that we mi identified Dr. Giampoli.
G20 42 mo. '130 42 mo. lease W&lt;th cash or trade eqUity
dawn. (G20-$495) (130-$450). Bank fee + tax and
license due almcepbon. 12,000 annual m&lt;leage. $.12

Clifton. Susco also provided an update on

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S2 79 IIIli.

hospital.

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"•ith
li.•t o/ ,•tandarti /u.\'111"1/
f~atur~.•: a -l-ymr/60,0£/0 mil~ Ba,•ic x~:,.
l '~hic/~ ll'~u·ranty; 2-1- hour Roal/,,itl~
JJ.,,,[,•tana Pro_qram Trtp Interruption
B~n~fi't,•; and our Fra Sal'ia f_,oan Car

school until his retirement in 1983. After his
retirement, Dr. Hall remained active in medi-

most recently was awarded two Navy

The front-wheel drive lnfiniti® G20'"

per m1le

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9

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�BUFFALO PHYSICIAN

Non-Profit Org.
U.S. Postage
PAID
Buffalo, NY
Permit No. 311

STATE UNIVERSITY OF NEW YORK AT BUFFALO
3435 MAIN STREET
BUFFALO NEW YORK 14214

ADDRESS CORRECTION REQUESTED

PLANTING

A

TREE UNDER WHICH

You WILL

NEVER SIT

DR. DEVILLO W. HARRINGTON, class of 1871, knew how to make his money grow. In fact, this man who in 1905 provided $5,000 through
his will for the University at Buffalo School of Medicine, is still supporting UB today through the endowment his bequest created.
THIS PERMANENT endowment in Dr. Harrington's name has grown to over $300,000 and today it supports the famous
Harrington Lecture Series, which twice a year brings distinguished scientific speakers to the School of Medicine and Biomedical Sciences.
DR. HARRINGTON'S LEGACY to UB is just one of many bequests which have established permanent and important endowed fu nds at
the school. They enable UB to provide scholarships to outstanding students, enhance scientific research, support excellence in teaching and
meet the ever-changing needs of the school.
YOU TOO can provide the School of Medicine with a measure of permanence through a bequest. Proper estate planning helps you
develop a smart financial plan. A charitable bequest provides the satisfaction that comes from planting a tree under which you will never
sit, but which will bear fruit for generations to come.
FOR A CONFIDENTIAL consultation on making a bequest to the UB School of Medicine and Biomedical Sciences, or to receive
materials to share with your attorney or estate planning advisor, please contact:
STEPHEN A. EBSARY, JR.
Assistant Dean and Director of Development, School of Medicine and Biomedical Sciences

UNIVERSITY AT BUFFALO (716) 829-2773
UNIVII!RSITY AT aUFFALO
SCHOOL 0,. ME:DICINII!

t5~
150

YEARS

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                    <text>State University of New York at Buffalo School of Medicine and Biomedical Sciences, Spring 1996

8

4

6

9

9

6

�BUFFALO PHYSICIAN

Volume JO , Number 2
ASSOCIATE VICE
PRESIDENT FOR
UNIVERSITY SERVICES

Dear Fellow Alumni,

Dr C uole 5rnth Petro
ACTING DIRECTOR OF
PUBLICATIONS
Kathryn A. ~"''ncr

AS WI: CELEBRATE the University at Buffalo s sesqUiccntenmal this

EDITOR

many talented physicians and scientists who have contributed to that

year, we reflect on the rich history of our med1cal school and the

jesSica Ancker

history. These indi\'Iduals were visionaries in their own era, lookmg

ART DIRECTOR

co~ld

Alan J. Kegler

into a future that others

ASSOCIATE DESIGNER

sesqlllcentenmal celebrate not only our school's past, but also our

julrr c.rerten

not sec. So it is fittmg that the

vision for the future

PRODUCTION MANAGER

We have a tendency to thmk that the past was somehow a

Ann Raszm;.mn Brown
STATE UNIVERSITY OF
NEW YORK AT BUFFALO
SCHOOL OF MEDICINE
AND BIOMEDICAL
SCIENCES

Dr. john :-.jaughton, \'icc PreSident
for Clmrcal Affarrs. Dccm

kinder, simpler time, when doctors were unburdened by the complicated issues we face
today, and inspiration and dedication were all that
, \vas needed It seems unfair, somehow.
Roswell Park did not have to spend two hours on the phone arguing to get an MRI approved .
James Platt \Vhite did not have to pay outrageous malpractice premiums. Matthew Ma.nn did
not have the quality-assurance police hounding hun about his C-scction rate. Austin flint

EDITORIAL BOARD

Dr John A RKhcn , Chairman
Dr. Martrn Brecher
Dr. Harold Brody
Dr. Richard L. Collms
Dr. Alan J. Drinnan
Dr james Kanski
Dr Barbara Marjcroni
Dr, Elizabeth Olmsted
Dr. Charles Pagand,
Dr. Margaret W . Parosk1
Dr. Thomas Raab
Dr. Stephen Spauldmg
Dr. Bradley T Truax
TEACHING HOSPITALS AND
LIAISONS

The Buffalo (,encralllosprtal

,\.ticlwd Shu11
The Children's llosprtal of Buffalo
Erie Count\' Medrcal Center
Mercy Hospital
Jl,llllard fillmore llosprtals
rrani~ Sm·a
• N ragara ralls Memorial \1cdrcal
Center
Roswell Park Cancer lnsmute
Sisters of Charity llosprtal
Dnmis MrCcuthv
\'rterans Affairs \Vrstcrn New York
Hcalthcan· Svo.,tem

did not have

to

worry about a \1edicaid audit. They didn't have to get CMI: credits, write

triplicate scripts, or attend endless hospital committee meetings Things were so simple back
then-if you call operatmg wnhout electric lights or antibiotics simple
In real It}, each generation has its own umque problems to face Our common denominator is that we overcome the challenges and learn ways to solve our problems. Despite all
the woes of modern medical practice, you?g people are applymg to our school in record
numbers. \\'hy? One reason is that despite the stresses

It

bnngs, medicine still offers the

intrinsic satisfaction of t._uring illness or helpmg people cope with what we cannot cure. The
other reason is that we have a ternfic medical school. I may sound like a proud mother
offering a somewhat biased opinion about how good-looking her children are but our
med1cal school offers an excellent education at a reasonable cost hy any objective standards
Our school has been acknowledged as an outstanding primary care/comprehensin' medical
school by a national magazine (which arrived at that conclusion \V nhout any mput from me)!
So how do we keep our medical school top notch m tough tunesl _Our Medical Alumni
Association is a key player in that mission Since its mceptwn m 1875, the Medical Alumni
Association has served to better the school in many ways. It allows us to stay in touch giving
us the opportunity to network and exchange Ideas. A casual conversation at an alumni

©The State t niwrsrty of New York
at Buffalo

reception ca"n lead to a major project for the Medical Alumm Association. C.cneral class

Buffalo Phv"rrun rs publrshcd

students choose what field of medicine they want to pursue.

quarterly by the State UnrvcrSlt)' of
New York at Buffalo School of
Medicine and BiomcdJCal 'icit:nu.·s
and the Olfrce ol Publicatrons. It rs
sent free of charge. toalumnr , fanrltv ,
students, rcsrdrnts and frrends. I he
staff resn\'l's the rrght to edrt all copy
and suhmisstons accepted for
publicauon
Address question.._, comments and
submisSions to: The Edrtor Bu{julo
Physificm, Statr l~ nivcrslt)' or New
York at Buffalo , Offit-c of Puhlr callons 136 Crofts llall , Buffalo ,
New York 14260

Send address (hanges to:

Buffalo

Physician. 146 Cl'~ Addrtron , H35
Miun Street, Buffalo, New York 14 214

reunion gifts fund much-needed scholarships. The Coi~munity•Physi&lt;.ians Program helps
In treating a patient, any physician can tell you the difference a supportive familr makes
family serves ro motivate, comfort, guide, and care for the patient. As medical alumni, we
are the family of our school. As a family, we are proud of the 150 years of tradition this yearlong sesquicentennial
celebratiOn
marks, and the MediCal Alumm Association looks to its
.
,
members for a \ tsion of the next 150 years. We also plan to have fun in the process.
\Vannest regards,

~~ W. ?OA.o~, MD
Margaret W . Paroski, MD.
Prrsidcnt, l\.1cdical Alumni Association

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150
Preparing for the 21st Century
-by john Naughton, M.D.
UB's MEDICAL ScHOOL AT

THE fOUNDlNG OF THE U

1\'ERSITY OF BUFFALO

The stories of three of UB's founding father
-by judson Mead
BUFFALO's

U

!QUE NETWORK OF TEACHING HOSPITALS

How the unusual relationship between the University at
Buffalo and its teaching hospitals evolved.
-by Ann Whitcher
PHOTO ESSA'r: LIFE AT THE MEDICAL SCHOOL

Two students bring us along during their daily routine.
-photos by Don Heupel, story by jessica Ancker

The medi cal faculty of the Uni versity of Buffa lo in 1861.
PHOTO: UNIVE R SITY A RCHIVES . UNIVERS ITY
AT BU FFALO

_.J

CoNTINuiNG A TRADITION or ExcELLENCE

Profiles of some of UB's young faculty .

m
m

MEDJCI'\J E or THE F UTURE

Members of the UB community speculate on what is to come.
C LASSNOTES

�•

ICa

Preparing for the 21st Century
This special issue of the Buffalo Physician celebrates UB's Sesquicentennial. The school's birthday is May
11, 1846, when New York State granted the charter to form the University ofBuffalo. Our Sesquicentennial
Celebration parallels the events from early 1846 through mid-184 7, when the first class was graduated.
The medical school was founded with strong community ties and a dedication to preparing excellent physicians committed to the highest quality of patient care
and community service. At least three ofUB's first seven
faculty members were unquestioned giants in medicine.
Dr. james Platt White, one of UB's founders and a
gynecologist-obstetrician, extended clinical teaching to
include the demonstration of live birthing. Dr. Austin
Flint was a peripatetic teacher, expert diagnostician,
prolific writer, and editor. Dr. Frank Hastings Hamilton,
a surgeon, introduced the use of ether as an anesthetic in
BY

JOHN

the iagara Frontier. These three set the course for UB's
medical school, consistent with Chancellor Millard
Fillmore's dream that UB should be "eminently useful" to
the citizens of Buffalo and western ew York.
Like all institutions in the young nation, UB had its ups
and its downs. A few of the high points:
• The recruitment of Dr. Roswell Park from Chicago to
head the Departments of Surgery in both UB and Buffalo
General Hospital was a major accomplishment. Park was
an internationally recognized surgeon with a broad range
of interests and tremendous energy and foresight. His

NAUGHTON ,

M . D .

DEAN , SCHOOL OF MEDICINE AND BIOMEDICAL S CIENCES
VICE PRESIDENT FOR CLINICAL AFFAIRS

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�Buswell, and a UB alumnus, Dr. Harry Laforge, helped
secure this bequest, which was shared between UB and the
University of Rochester Medical School.
• A group of local physicians (alumni and non-alumni)
formed a fund-raising organization, the Annual Participating Fund for Medical Education (APFME). The first
funds were used to recruit Dr. Hermann Rahn to become
chairman of the Department of Physiology. Today, the
funds are endowed and the revenues support Continuing
Medical Education programs. Barbara Mierzwa serves as
the APFME Director for CME.
• The Medical Alumni Association supports the professional development of medical students, residents, and its
other members. A major new initiative is the annual
recognition of a Distinguished Medical Alumnus.
• UB and its teaching hospitals established a nationally
recognized model for graduate medical education. The
Graduate Medical Dental Education Consortium of Buffalo has demonstrated the importance of shared gover-

memory is honored through the cancer institute and the
local society of surgeons that bear his name.
• During the troubled years around UB's centennial, a
leader emerged who served as dean for 12 years, Dr.
Stockton Kimball. 1 regret that we never met. He is
reputed to have been a warm person with a great deal of
foresight, tenacity and fortitude who provided the leadership to broaden the medical school's missions and to
relocate the school to the University Campus.
• During World War 11, the school added two strongwilled, well established educators and scientists to its
basic science faculty , Dr. Ernest Witebsky and Dr. Oliver
P .Jones. These two , who helped establish UB's strength in
fundamental biomedical research , were named Distinguished Professors by the SU Y Board of Trustees.
• The school received its largest endowment from a
Buffalo industrialist, Ralph Hochstetler, after his death in
1955. The revenues support physicians as they prepare to
become clinical scientists and faculty committed to biomedical research. Hochstetler's brother-in-law, Dr. Henry

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�"For a long time the defects in the system of medical instruction in the
neighboring colleges at Fairfield, Geneva, and Willoughby had been the subject of
remark among my medical associates and myself It was on all hands agreed that the
great desideratum, clinical instruction, could not be supplied in these rural schools.
Without an opportunity to apply at the bedside the precepts inculcated in the
lecture-room, the system of teaching by lectures can never be successful in making
good practitioners.
"Moved by these considerations, and influenced partly, no doubt, by the hope of
personal professional advancement, ifthey could show they merited it, two or three
young men, after careful deliberation, set about procuring a charter for a medical
college. In this enterprise the older practitioners not only declined to participate but
tried to discourage its undertaking. Nothing daunted by this opposition, aided by a
few laymen, we proceeded in the winter of I 845-6 to procure a charter for a
University. In the latter part of the same year we organized a medical department
and appointed a corps of professors."- from remarks by Professor James P. White,
M.D., at the inaugural dinner of the Alumni Association on Feb. 23, 1875.
The "two or three young men" were White himself, Austin Flint, and Frank
Hastings Hamilton, all then in their early or mid-30s, and all destined to make their
marks on medicine and medical education in the United States.

By

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�6

JAMES PLATT WHITE

A pioneer in American obstet-

rooms and laboratories for les-

rics and gynecology and in the

sons in practical anatomy and

teaching of clinical obstetrics,

chemistry. The faculty con-

James Platt White may rightly be

sisted of White, Flint, Hamil-

considered first among equals in

ton, Charles A. Lee, James
Webster, Charles B. Coventry,

the founding of the University of

and George Hadley. Hamilton was

Buffalo School of Medicine.

a faculty member of the Geneva

Of the three principal founders,

Medical College but had taken up resi-

White had lived in Buffalo longer than

dence in Buffalo two years before; he re-

Austin Flint and Frank Hastings Hamilton.

cruited Lee, Webster, Coventry, and Hadley from

White's father had moved the family from Austerlitz,
Geneva.

Y (near Albany), to the Buffalo area when White was five

White cooperated in the founding of the city's first

years old. He was educated in local schools and at

hospital, the Buffalo Hospital of the Sisters of Charity, as

Middlebury Academy in Vermont.
White began his medical education in Buffalo in the

well as in the establishment of Buffalo General and the

office ofDr.Josiah Trowbridge in 1830 and then spent three

Providence Asylum for the Insane. He was also instrumen-

years attending medical lectures at the Fairfield Medical

tal in the establishment of Buffalo State Hospital.

College in Fairfield, Y. After receiving his medical degree

On Jan. 18, 1850, White wrote a new chapter in Ameri-

from Jefferson Medical College in Philadelphia in 1834 at

can medical education when he conducted a clinical dem-

the age of23, White set up a practice in Buffalo specializing

onstration in obstetrics before 20 students in the new

in the diseases of women and children. He also traveled to

facility the university had built the previous year. The

Europe to further his studies in Edinburgh, Paris, and

students were permitted to perform a vaginal examination

Vienna. According to one biographer, "he possessed

of a woman in labor and then to witness her delivery. White,

boundless physical energy which gave him a forceful ,

who knew this teaching method to be accepted in many

aggressive personality."

European medical schools, and who believed that medical
students should witness a delivery before entering general

The first class of the new University ofBuffalo met in the

practice, called it "demonstrative midwifery."

spring of 1847. The facility , a renovated Baptist church,
included an amphitheater that could accommodate 200

The demonstration became a topic for vociferous public

students and also served as a dispensary, as well as lecture

discussion. Physicians who had opposed the founding of

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�the medical school were quick to attack White, while his

nal of the Medical Sciences, published in Philadelphia, but

students passed a resolution congratulating and thanking

White was supported by medical journals in Louisville and

him. The Buffalo Commercial Advertiser editorialized in

Cincinnati. The Committee on Education of the American

favor of his demonstration, but a few days later the Buffalo

Medical Association reponed in 1851 that demonstrative

Courier carried a highly charged editorial, signed "L,"

midwifery was entirely unnecessary.

stating that "a precedent had been set for outrage indis-

Clinical teaching in obstetrics was soon well established,

criminate." In a letter to the Buffalo Medical journal, 17

nonetheless. Twenty-five years later White was pleased to

Buffalo physicians called demonstrative midwifery unnec-

remind an audience of medical school alumni that "this

essary and "grossly offensive." When Dr. Horatio Loomis

method of teaching has now been introduced, in some form

had additional copies of the Courier editorial printed and

or other, into all the leading institutions of the land, and in

distributed, White sued him for libel. White was supported

many, is made a prerequisite to graduation."

at the trial by the testimony of Dr. Chandler Gilman,

james Platt White was the only one of the three principal

professor of obstetrics and disease of women and children

founders of the medical school to spend his entire career in

at the College ofPhysicians and Surgeons in New York City.

Buffalo; however, he was far from parochial in his associations.

Gilman stated that he had performed similar examinations

He was a founder of the American Gynecological Society and, in

while two or three students observed, and that he hoped to

1877, chairman of the section on obstetrics and gynecology and

emulate White's demonstration of an actual delivery.

vice president of the American Medical Association that had

Loomis was acquitted, primarily

inveighed against his clinical teaching

because the jury ignored the judge's

a quarter of a century before. He was
Physicians who had

charge; however, White felt that demonstrative midwifery had been

also extremely active locally and was
one of the founders of the Young

opposed the founding of

Men's Association, the Academy of

vindicated.
White's demonstration and

Fine Arts, the Buffalo Historical Soci-

the medical school were

ety, and the Buffalo Club. At the time

Gilman's testimony on his behalf
quick to attack White,

were the target of a vehement editorial by the influential American jour-

of his death, he was for the second
lime dean of the medical school he

while his students passed a

had brought into the world.
resolution congratulating
and thanking him.

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�AUSTIN

FLINT
G

In 1836, 24-year-old Austin Flint,

during his eight-hour visit was

with his wife and baby son, arrived

enough to generate three papers,

in Buffalo from

published in 1845, 1852, and 1875

orthampton, MA,

to set up a medical practice.

(presented in 1873), on the com-

Within five years he had pub-

municability of typhoid.

lished papers on rubeola, sudden

The illness had struck 28 of the

death, the use of quinine in intermit-

4 3 inhabitants of the village, killing 10

ting fever, and the connection between

of them, a few weeks after a traveler from

dyspepsia and the mind. By the time of his

Massachusetts had fallen ill and died at the

death in 1886, Flint had published more than 240

village inn. Flint discovered through correspon-

articles on almost every aspect of internal medicine, as

dence that the traveler had probably "left home with the

well as several books and a widely adopted medical

germicidal principal of typhoid in his body"; he con-

textbook. He had also made significant contributions to

cluded that "the subsequent cases were due to infection or

the fields of physical diagnosis and epidemiology, served

contagion introduced into the closely congregated com-

as president of the American Medical Association, helped

munity. " Although he noticed that three families who did

found the University of Buffalo and another medical

not drink from the village well escaped the disease, he

college, and been a faculty member at four other schools.

attributed their health to better nutrition because they

Flint was the fourth generation in his family to practice

were also wealthier. After diagnosing the disease and

medicine (and he was followed in the profession by a son

testing the well water, Flint dismissed an accusation from

and grandson). He was educated at Amherst College and

villagers that the epidemic had been caused by deliberate

received his medical degree from Harvard College in

poisoning of the well.

1833. Although he did not study abroad, Flint was well

Flint's early papers on contagion were quoted by john

acquainted through his Harvard teacher with the statis-

Snow, a pioneer in epidemiology, in a famous oration in

tical case recording methods advocated by the Parisian

1853. After that speech, Snow succeeded in stopping an

clinician Pierre C. A. Louis. In 1843, Flint, who had been

outbreak of cholera in London by taking the handle off a

appointed health officer in Buffalo the year before, was

pump to prevent people from drinking the contaminated

called to the village of

water.

onh Boston, 18 miles away, to

investigate an outbreak of severe illness. He diagnosed the

Years later, after the transmission of typhoid fever

illness as typhoid fever. The information he collected

through contaminated water had been demonstrated,

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�Flint revisited his North Boston findings and found that

natural gift, nor does it accompany as a matter of course

there had been a privy close enough to the public well to

the acquisition of knowledge one acquires from reading or

contaminate it with infected excreta from the first victim.

didactic lectures. It is an art to be acquired." Flint was

In his 1873 presentation to the American Public Health

described as "a large man, with a full voice," always

Association, Flint said, "It is perhaps the most remarkable

solicitous of the comfort and feelings of his patients.

experience on record as embracing a combination of

In 1852 he left Buffalo to take a position at the University

circumstances proving, in the first place, the communica-

of Louisville. That year he received an American Medical

bility of typhoid fever and, in the second place, rendering

Association prize for his essay "Variations in Percussion

vastly probable, if not certain, the communication by

and Respiratory Sounds." Four years later Flint returned to

means of a contagium contained in drinking water. " He

Buffalo as professor of pathology and clinical medicine. His

recommended sanitation precautions that, unfortunately,

work on heart sounds resulted in a second AMA prize in

went unheeded for another half-century.

1859. In 1862 he published a paper describing the particu-

The reputation Flint had established through his early

lar heart murmur that still bears his name.

publications prompted an invitation in 1844 to teach at

The characterization of the "Flint murmur" occurred at

Rush Medical School in Chicago. He accepted, but soon

Charity Hospital in New Orleans. The peripatetic Flint

realized that he preferred living in Buffalo. Once resettled

was by then dividing his time between Buffalo in the

in Buffalo, he founded the Buffalo Medical]ournal, which

summer and

he edited for the next decade.

ew Orleans in the winter.

Flint left Buffalo permanently in 1860 to become professor

In 1845, Flint attended the

ational Medical Conven-

of pathology and practical medicine at Long Island College

tion in New York City as the delegate from the Buffalo

Hospital. He helped establish Bellevue Hospital Medical Col-

Medical Association. He was appointed to a committee

lege and spent the rest of his life in New York City.

charged with studying the requirements for granting medi-

Flint's son Austin Flint Jr. described the variety of

cal degrees. The committee's recommendations ultimately

experiences that had made his father one of the great

included extending the year's lecture period from four to six

clinicians and teachers of his age: "During his professional

months; requiring attendance for two years of lectures;

career he encountered soldiers in camp and in barracks;

requiring a total of three years of study, including three

the rich and the poor; those afflicted with diseases inci-

months of dissection; and requiring that all medical facul-

dent

to

lives of ease and luxury and paupers in hospitals;

ties have at least seven professors.

the pioneers of western New York

After helping to found the Uni-

and the inhabitants of the metropo"The ability to observe

versity of Buffalo, which held its
first classes in 1847, Flint served as

lis ... cases observed in the experience of a quarter century as a gen-

is not a natural gift,"

the school's professor of medical

eral practitioner, and of more than

theory and practice for six years. He

another quarter century as a con-

Flint said. "It is an art

shared james Platt White's belief in

sulting physician, including epito be acquired."

the utility of clinical teaching, say-

demics which have occurred in this

ing, "The ability to observe is not a

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�FRANK HASTINGS

HAMILTON

1813-1886

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Something of the single-

growing city of Buffalo in or-

mindedness of Frank Hastings

der to have greater access to

Hamilton, who once wrote (about

surgical cases. He continued

himselO that "a man whose busi-

to teach at Geneva untill848.

ness is in information rather than

When the medical de-

pleasure does best to travel alone,"

partment of the University of

is evident in what he accomplished

Buffalo enrolled its first class,

r

very early in his life. Entering Union

e

College as a sophomore at 14, he earned

Hamilton was professor of principles and practice of surgery and

his bachelor's degree three years later, then

clinical surgery, a chair he held until

studied anatomy in the office of Dr. John G.

1860. He was also the school's first dean. A
contemporary described Hamilton as "rather cool and

Morgan in Auburn, NY, for a year before attending medical
.t

lectures at the Fairfield Medical College in Fairfield, NY. He

reserved to strangers, but open-hearted to trusted friends .

11

was licensed in 1833 by the Cayuga County Medical

He could not conceal his utter abhorrence of the arro-

,,

Censors; he earned a medical degree from the University

gant. "

.-

of Pennsylvania in 1835. By then he was 22.

.,

Before the advent of anesthesia, surgery was performed

As surgeon for the Auburn State Prison, Morgan could

as rapidly as possible and the surgeon depended on a

k

obtain the bodies of prisoners who had died. Hamilton

thorough knowledge of anatomy. In his first lecture at

,_

Was his demonstrator in anatomy untill834, when Mor-

Geneva in 1840, Hamilton told his students, "You must

gan was called to the faculty of the Geneva Medical

persevere in penetrating and threading the windings of

College. Hamilton returned to Auburn after his study in

anatomy, and you must obtain complete mastery over

11

Philadelphia and taught anatomy and surgery in his pri-

your nervous cords, that ... the keenest cry of suffering

1-

vate office, mainly to students from the Theological Semi-

shall not cause a thread to vibrate. "

1-

nary at Auburn. In 1839, Hamilton was appointed profes-

Hamilton was a preeminently skillful and inventive

s

sor of surgery at Fairfield Medical College; not quite two

surgeon. In The History of Surge1y in the United States

years later he succeeded his former teacher at Geneva

1775-1900, Ira M. Rutkow, M.D., calls him "one of the

when Morgan left the schooL Hamilton traveled and

most versatile of 19th-century American surgeons. " A

studied in Europe during 1843-44, then moved

natural mechanic, Hamilton invented a variety of surgical

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�instruments, according to an article by Oliver P. Jones,

the first battle of Manassas, he rapidly gained a wider

Ph.D., M.D., for the 1973 Buffalo Physician. Jones also

scope of responsibility as brigade surgeon, medical direc-

said Hamilton was one of the first surgeons to excise the

tor of a division, medical director of an army corps, and

metatarsophalangeal joint for bunions and to remove the

finally, in 1863, Medical Inspector of the United Stares

central portion of the thyroid. To make joint amputations

Army. He had published A Practical Treatise on Military

more precise, Hamilton described what he called 'keys

Surgery in 1861 and brought out a second, enlarged

and guides' to the articulations.

edition in 1865. During the war , he wrote to his wife that

At the Buffalo Hospital of the Sisters of Mercy, in 1854,

"it is no uncommon thing for a surgeon in the field to be

Hamilton demonstrated the efficacy of closing old ulcers

compelled to change his position once or twice during an

by skin graft when he successfully transplanted a 7" x 4"

operation, on account of a change in the direction or range

flap of skin from the left leg of a patient to close an ulcer

of the shots. "

on the right leg. It was also in Buffalo that Hamilton wrote

Hamilton resigned his commission late in 1863 and

the preface to his influential book A Practical Treatise on

returned to teaching at Bellevue. He was made professor

Fractures and Dislocations , published in 1860. The first

of the principles and practice of surgery and surgical

American text to deal in depth with fractures , it was used

pathology there in 1868. Four years later he published The

throughout the country and appeared in seven editions,

Principles and Practice of Surgery. He described its purpose

the last in 1884.

as "to supply within the compass of a single volume of

Frank Hamilton and Austin Flint were both members

moderate size, the instruction necessary to a full under-

of the Long Island College Hospital's first faculty. Here

standing of all the subjects belonging properly and exclu-

Hamilton realized an ambition in clinical instruction that

sively to surgery. " The volume went through three edi-

he had harbored for 20 years: at the new college in

tions , the last published shortly before Hamilton died in

Brooklyn , students were able to

1886.
In an address to the graduates

pass directly from the lecture hall
Hamilton was a surgeon in

to the hospital wards for bedside

of the University ofBuffalo in 1853,
Hamilton gave them his final ad-

teaching.
the 3 I st Regiment of the

A year after moving to Brooklyn, Hamilton became professor of

monition as a teacher , urging them
to study advances in medicine

New York Volunteers in

military surgery, fractures, and dis-

during their careers. He warned
the Civil War. His two sons

locations, and professor of clinical

that those who did not would , as

surgery at Bellevue Medical Col-

old men, " ... discover in their cruwere in the regiment and,

lege. He volunteered as surgeon
for the 31st Regiment of the New

cibles some few scanty facts which ,
if they had looked to the experi-

he wrote, "I wanted to be

York Volunteers immediately after

ence of others, they might have
near my dear children in

the outbreak of hostilities in the

known at 30. It is quite as often,

Civil War. His two sons had joined

we fear , that they die wholly uncase they were wounded."

the regiment and , he wrote , "I

conscious that the science which

wanted to be near my dear children

they faithfully intended to prac-

in case they were wounded. " In

tice all their lives is a century or

charge of a general field hospital at

more ahead of them."

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In 1953, the medical and dental
school moved to this new building from its old High Street
home next to Buffalo General
Hospital. Samuel P. Capen Hall
(renamed Sidney Farber Hall in
1974) became the nucleus of
UB's South Campus.
PHOTOS : UNIVERSITY ARCHIVES ,
UNIVERSITY AT BUFFALO

��BY ANN WHITCHER

When the University of Buffalo
opened in 1846,
medicine
was
about to begin a
half-century of dramatic advances,
and the hospital
Was about to
change from a
charity service for
the poor to a pivOtalcommunityinStitution. ln the
mid-19th century,
mostmedicalpractitioners had little ~BUFFALO GENERAL HOSPITAL BEFORE THE TURN OF
or no formal education; such primitive opened in 1858, it, too, became an affilimethods of therapy as bleeding, blister- a ted teaching hospital for the medical
school. Medical school faculty had twice
ing, and purging were still in use.
Clinical training for physicians, too, been part of unsuccessful efforts to found
Was extremely limited, owing to the a city hospital, in 1846 and 1854; with
state of hospital care. A sojourn at even the establishment of Buffalo General,
the best endowed of hospitals was sta- they finally succeeded. The association
tistical!y riskier than home care, due to between the school and the birth of the
the hygienic horrors of the time. Surgi- hospital inextricably linked the two in
cal anesthesia was gradually introduced the public mind.
When Buffalo General appointed its
only after the late 1840s; asepsis was not
Practiced until much later in the cen- first medical staff, most of the physitury.
cians were associated with the univerNonetheless, hospitals were valuable sity, a pattern that still holds true today.
Places for young doctors to see a variety By 1869, the medical school could asof patients and gain the kind of ex peri- sert that Buffalo General "will be open
for clinical instruction . . . o hospital
ence they would need in practice.
. The University of Buffalo established fees are required; the Faculty having
lts first relationship with a hospital when made arrangement for the admission of
Sisters Hospital was opened in 1848 by all the members of the class without
the Sisters of Charity. Frank Hastings charge."
liamilton and Austin Flint, both faculty
A rapid acceleration in medical unmembers at the medical school (then derstanding followed the introduction
located a block away from the hospital of antisepsis in the 1870s and asepsis in
at Main and Virginia streets) became, the 1880s. When the renowned German
respectively, Sisters' attending surgeon surgeon Ernest Von Bergmann was asked
and physician. When Niagara Univer- in 1882, "What's new in surgery?" he is
Sity formed a medical school in 1883, said to have replied, "We wash our hands
Sisters switched its primary affiliation; before we operate ratherthan afterward."
however, Niagara's medical school was
Actually, the surgeon of the 1880s
iissolved 15 years later, and the UB- was likely to give a cursory wipe on the
lsters connection was restored, al- sleeve to a dropped instrument, then
though probably not with the intensity sanguinelycontinuewiththeprocedure.
lt had once enjoyed.
By the 1890s, however, aseptic surgery
When Buffalo General Hospital became a more and more common hos-

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pita! practice; there
were now autoclaves, sterilized
dressings, and rubber gloves. Knowledge of pathogenic
microorganisms
also played a major
role in increasing ~
the public's trust in ~
hospital surgery be- --~
tween 1875 and ~
World War I.
~
When the ~
medical school re- 9
~
cruited Roswell al
THE CENTURY .
Park from Chicago
in 1883 to become professor of surgery,
he quickly took on additional duties as
attending surgeon at Buffalo General. A
man of wide culture who had studied in
Europe, Park "taught the value ofLister's
approach, as well as aseptic methods,"
Evelyn Hawes wrote in her history of
Buffalo General. "The faculty of the
medical school was virtually the same as
the attending staff of The Buffalo Genera! Hospital; medical students attended
the hospital clinics, and observed procedures of their university professors at
close hand."
"The growth of the whole idea of
residency-hospital training after medical school-really evolved from the mid1800s," says Roseanne Berger, M.D., UB
associate dean for graduate medical education. "People graduated from medical
school and didn't have sufficient medical training, so they sought apprenticeships in hospitals, but these experiences
were highly variable."
By 1890, the johns Hopkins Hospital
had coined the term "resident" to describe individuals who had completed
one year of hospital training, followed
by specialized training provided by the
medical school faculty. "What made it
unique was that, up to then, such training was under the auspices of various
hospitals," Berger says. "A teacher of
residents may or may not have been
affiliated with a medical school, or hold

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�Research Laboratory (forerunner of
today's Roswell Park Cancer Institute)
to be built on High Street, neighbor to
both Buffalo General and the medical
school, which had moved to a new building on High Street in 1893. In 1911,
Gratwick became a state facility, initially known as the Institute for the
Study of Malignant Diseases.
A number of new hospitals and
smaller clinics were established in Buffalo between 1870 and 1920, some run
by specialists in rival schools of medicine. According to Another Era, thesesquicentennial pictorial history of the
medical school , "competition among
regular, homeopathic, and eclectic physicians intensified, culminating in the
founding of the Buffalo Homeopathic
Hospital (later Millard Fillmore) and
Pierce's Invalids' Hotel. Ethnic and religious groups started their own hospitals, some of which became affiliated
with the medical school while others
have since closed or consolidated."
Mercy Hospital, now one of the nine
teaching hospitals, was opened by the
Sisters of Mercy in 1904.
A more clinically oriented medical
education evolved throughout the country after 1910, when the Carnegie Foundation for the Advancement of Teaching published a harshly critical evalua-

a faculty appointment.
radical at the time to introduce this
concept of organizing residency training-as opposed to medical school training-under the auspices of a medical
school."
By the 1890s, Buffalo General's medical staff included many distinguished
practitioners; the close connection between the hospital and the university
helped their efforts to integrate scientific medicine and hospital care. When
Roswell Park became ill with diphtheria
in 1893, he chose to recover in Kimberly
Cottage, Buffalo General's facility for
contagious patients-a clear endorsement of the therapeutic standards that
had been achieved. The gesture must
have been appreciated by the house staff
and ward nurses. This was an age, after
all, when those running the hospital
were not often its patients, and when
those with financial means usually preferred treatment at home.
Forging another link in Buffalo's
health-care network, Roswell Park and
Buffalo Evening News publisher Edward H. Butler Sr. secured legislative
funding in 1898 for a cancer research
laboratory in the medical school. By
1900 the institute had outgrown its lab
spac: of just a few rooms. A gift from the
Gratwick family enabled the Gratwick

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tion of medical education, the Flexner
Report. Charles E. Rosenberg says in his
book, The Care of Strangers: The Rise of
America's Hospital System , "That evolution grew out of an intricate symbiosis
between hospitals constantly in search
of staff, on the one hand, and on the
other, physicians who sought clinical
training and status. " By 1914, more than
75 percent of medical graduates in the
country were taking an internship.
"One of the things that grew out of the
Flexner Report," says UB medical school
dean John Naughton, "was that more
and more medical schools did have an
identifiable hospital or two that were, by
perception anyway, controlled by them.
That has never existed in Buffalo."
By the time the Flexner Report came
out, a number of other hospitals were also
loosely affiliated with UB. One was the
Children's Hospital of Buffalo, which had
opened in 1892. Another was an institution devoted to tuberculosis that evolved
into City Hospitalin 1918. Later renamed
E.j. Meyer Hospital, the institution in
1946 became a county hospital that was
the forerunner of Erie County Medical
Center. UB's affiliations with Children's
and City Hospital were informal by today's
standards, but they made possible the
variety of clinical settings enjoyed by
medical students of the period.

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�A 1934 evaluation report from the
C_ouncil on Medical Education and HosPitals lists clinical facilities for teaching
~t Buffalo City Hospital, Children's and
. uffalo General. Heads of depanO.:ents
In the me d'ICa] school held equivalent
Positions m
· t h e Bu ffalo City Hospital.
Staff
·
appomtments, however, were reserved for the hospital's board of managers. Buffalo General and the medical
school h d
ha
a no formal agreement, perps because of their long history of
Wok'
r mg together. "All visiting men are
llJ.emb ers o f the faculty " the report
noted A « · f
,
. · n m ormal agreement" also
existed b
Ch·
etween the medical school and
Ildren's.

had lobbied for a new building on High
Street. The Buffalo General Hospital had
offered a block ofland on High Street for
the new building; others saw what is
now the university's South Campus as a
more logical site. Some feared that put-

l . By 1945, most of the medical school's
k
c Inical
Wor was done at E.J. Meyer. All
THE HOUSE STAFF OF MILLARD
casesent . h
FILLMORE HOSP ITA L, 1 93 1.
enng t e hospital, including out.
Pallent
.
' were available for teaching. Buf- ting the new medical-dental facility near
f 1
a o Gen l
era treated all types of patients
except"
, Buffalo General would allow the hospi.
mental, contagious and tubercu- tal to dominate it. In the end, the counIosis"
.
to an evaluation report cil approved the South Campus plan,
rrollJ.' thaccordmg
A ,
.
c .
e MAs Council on Medical Edu- and Samuel P. Capen Hall was opened
allon and H
. l
ospita s and the Association in 1953 (it was renamed Sidney Farber
of Am .
encan Medical Colleges.
Hall in 1974);Sherman followed in 1958.
According to council minutes, UB
P The relationship with Children's apeared t b h
194 . 0 e t e most solid, the AMA's Chancellor Samuel P. Capen displayed
··
h epresenceof his customary judiciousness and vision
a 1. 5snetea
msa1·d ,citmgt
.
laJson
·
th h
commntee representing both in weighing the thorny matter. "He cited
""e ospital and the school that deter- the advantage of cooperation in every
.,,Inect t ff
w
sa appointments. Although there possible way, not only with all the hosas still
f
th
no ormal agreement between pitals with which the medical school
llJ.ed·
I
e
h
lea sc h ool and the two general now cooperates, but probably also, as
b ospitals, the report noted that "mem- time goes on, with a number of others.
ers of th
ff
llJ. ct·
e sta are also members of the As he saw it, medical education is just at
e leal h 1
""
sc oo and the heads of depart- this moment at the beginning of a large
'"ents at h h
.
te
t e ospnal are on the commit- expansion into somethmg distinctly dif! es Which head the din ical departments. " ferent and more popular than it has
n 1948
y
, ground was broken for a new been in the past. There is an intensive
eterans Ad ..
Pin
mmistration hospital, cap- drive in public interest in better and
fo gByears of effort to secure a VA facility more extended medical care."
r uffalo.
~~~~~~~~if.~
t What must have been a
ense m .
eetmg of the UniVersity C
on J
ounciltook place
· une 10 , 1948 , [o IIowlog
ct· a period of contentious
lscuss·
of h Ion on the location
. ,s new
h t e uni·versny
d OllJ.e for its medical and
ental schools which had
l on
·
'
lii ~ smce outgrown the
· g Street facility Many
TH E ST AF F OF B UF F ALO GENERAL IN
In the
d.
.
me leal community
B UI L DIN G AMPHITH E A TE R , C . 19 38.

Medical school dean Stockton
Kimball echoed these thoughts. No one
hospital would be sufficient for the teaching needs of the university, he contended. Indeed, it was his view that the
strength of the medical school lay in the
large amount and variety of clinical
material available at all the hospitals.
By 1950, the medical school had
teaching agreements with E.J Meyer,
Buffalo General, Millard Fillmore Hospital, and Children's. While there was
no formal agreement with Roswell Park,
the two institutions were affiliated for
teaching purposes.
By 1956, extensive clinical facilities
were available through agreements-now
written-with Buffalo General, E.J
Meyer, Children's, and Millard Fillmore,
plus an "understanding" with Roswell
Park. A 1965 report from a visiting team
representing the AMA and the Association of American Medical Colleges noted
that the school had since been given full
accreditation, but repeated past concerns
about "the basic hospital domination of
the medical school and the need for
strengthening the basic science areas."
Following the university's merger with
the State UniversityofNewYorkin 1962,
there were new layers of complexity to be
considered. For one thing, faculty communication was hampered, partly by "the
geographic separation of clinical facilities," the 1965 evaluators commented.
"''m sure the state did not have an
understanding of all these relationships
between the medical school and the
hospitals," Naughton says. "There was
the assumption, at least locally, that the
state would build a medical center for
UB." Various studies ensued "and a lot
of money was spent on the planning ...
Somewhere along the line,
as I understand it, (UB)
President (Martin) Meyerson and Governor Nelson
Rockefeller decided that ~
the better place for this &lt;~
medical center would be ~
i:
the Amherst Campus and ~
not on the old campus." In g
196 7, plans were an- &amp;
g

nounced to construct a ~
university hospital on the ~
Amherst Campus, but

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these plans never materialized.
"By the time I came here in 1975,"
Naughton says, "it was pretty clear that
the state wasn't going to put another
hospital in Buffalo, and therefore that if
we were going to survive as a medical
school in a teaching community, we
needed to develop a different strategy."
Paving the way to the modern hospital network were several key reports in
the 1960s that urged institutional responsibility for graduate medical education. The 1966 Millis report of the
AMA's Citizens Commission on Graduate Education ofPhysicians, for instance,
said that teaching hospitals must demonstrate responsibility for medical education through the creation of a medical
education committee. They also recommended that an agency be authorized to
plan, review, and coordinate standards
for graduate medical education.
"The formation of the Graduate Medical Dental Education Consortium ofBuffalo in 1983 was really the culmination of
an arrangement that had existed in Buffalo for a long time," UB's Roseanne
Berger states. "Residency programs were
based in hospitals throughout the city,
because there was no single university
hospitaL A single program actually shared
the resources of multiple hospitals, and
the oversight of that single residency
program would be charged to a particular educator, a program director, but the
financial arrangement-as to who would
be responsible for supporting the program-became very complicated."
By the early 1980s, there were new

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requirements for accreditation under
the auspices of the Accreditation Council for Graduate Medical Education.
"That organization accredits the various residency programs and the various
specialties and ensures that each program meets a set of standards that are
established by a specialty-specific residency review committee," Berger explains. "In 1982, it required that each
program identify a single sponsoring
institution. In Buffalo-since the majority of programs were located at multiple hospitals-just deciding who that
single sponsoring institution was became a problem.
'This became an opportunity to establish the consortium, and in so doing it
pulled the hospitals together around one
mission: graduate medical education. A
governing structure was then established
to create a formal process for the hospitals to work collaboratively for structur-

Today'steaching hospitals:
The Buffalo General Hospital
The Children's Hospital of Buffalo
Erie County Medical Center
Mercy Hospital
Millard Fillmore Hospitals
Niagara Falls Memorial
Medical Center
Roswell Park Cancer Institute
Sisters of Charity Hospital
The Veterans Affairs Western New York
Healthcare System

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ing, reviewing, and thinking about issuE
of resident training in the region."
Today, the consortium plans and di
rects all Accreditation Council residenc
and fellowship training in Buffalo aill
Western New York. Resident salarie
and benefits are equal for each training
year level throughout the region and ar
paid by the consortium. A second initia
tive, the Western New York Health Sci
ences Consortium, formed in 1987, i
directed toward improving the area'
health-care delivery system.
Michael Noe, M.D., vice presiden
for professional affairs at Buffalo Gen
eral, provided key leadership in orga
nizing the consortium. "From the be
ginning," Naughton says, "Mike and th1
residency training directors furthere1
the understanding of the strength, eco
nomics, and improved training qualitj
that could come from a single, coordi
nated organization committed to share
governance."
Today, the Graduate Medical Denta
Education Consortium coincides wit
separate university agreements with th
teaching hospitals. Resulting joint en
terprises have produced more resideD
cies in primary care, regional centers fo
organ transplants and positron emi5
sion tomography imaging, and a rura
health initiative. Medical school an
consortium initiatives are flourishing i
biomedicine, epidemiology, and clini
cal trials, and the school has receive
major funding to expand its generaliS
medical education programs.
Throughout its history, the medici!
school has drawn on a network of affih'
ated hospitals to advance its missiofl
according to a ugh ton and joyce Vana
Ph.D., clinical assistant professor of so
cial and preventive medicine. The tW0
collaborated on a recent article in the:
American Journal of Public Health.
'This arrangement," they wrote, "ha5
been sometimes divisive and always challenging, with conflicting loyalties an~
allegiances occasionally placing hosp1til
service needs before medical educati011.
However, mutual tolerance and depefl'
dence have also developed. In Buffalo rhC
need for collaboration in education, re'
search, and service has proved stronger
than the drive for autonomy." +

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�These students were some of the
last to study at the High Street
university building. By 1949,
when this picture was taken, the
decision had already been made
to move UB to Main Street.
PHOTO: UNIVERSITY ARCHIVES , UNIVERSITY
AT BUFFALO

Old Alumni Hall was the
lecture room in the High Street
building.
TIAN YEARBOOK,
PHOTO : t947 MEDEN
ERSITY AT BUFFALO
L E R S I T Y ARCHIVES . UNIV

�BY

.JESSICA

ANCKER

THE

PHOTOS BY DON

LONG

THING

HOURS

ELSE

EVOLVES

ABOUT

NEVER

CHANGE,

MEDICAL

CONSTANTLY

TO

BUT

EDUCATION

KEEP

EVERY-

UB

AT

ABREAST

HEUPEL

OF

NEW

TECHNOLOGIES, TREATMENTS AND ATTITUDES. TWO CUR-

STUDENTS

TYPICAL

DAY TO

KRISTEN

BROUGHT

PROVIDE A

ANDRESEN,

A

US

GLIMPSE

24-YEAR-OLO

ALONG

INTO

WITH

LIFE

SECOND-YEAR

AT

THEM

ON

UB TODAY.

STUDENT,

WANTS

PRIMARY CARE DOCTOR IN EITHER GENERAL MEDICINE OR PEDIATRICS .

WHO

GREW UP ON

A

LONG

ISLAND FARM,

WILLIAMSVILLE THAT OVERLOOKS A

HAS

RENTED

A

A

TO

BECOME

A

KRISTEN,

SMALL HOUSE IN

NEIGHBOR'S PASTURE, COMPLETE WITH

HORSES. SHE DOESN'T HAVE MUCH TIME TO ADMIRE THE VIEW, THOUGH .

ANY

FREE

TIME

SHE

CAN

SNATCH

FROM

HER

COURSES

IS

SPENT

PREPARING FOR HER FIRST NATIONAL BOARD EXAMS IN ..JUNE.

MOST OF KRISTEN'S

DAYS ARE SPENT IN THE LECTURE HALL, AS

HAS LONG BEEN TRADITIONAL FOR FIRST- AND SECOND - YEAR STUDENTS.

BUT US IS INTRODUCING CLINICAL MATERIAL EARLIER AND EARLIER IN THE

T

H

E

�CURRICULUM.

KRISTEN'S PATHOLOGY LECTURES,

CORRELATIONS

DISEASES

IN

WHICH

STUDENTS ARE

PRACTICING

PHYSICIANS

PRESENT

RECENT

EXAM.

IN THE

IT'S

PROBLEM-SOLVING.

THAT

ILLUSTRATE

THE

CHANCE TO LEARN ABOUT PATIENT CARE BY SEEING PATIENTS AT BUFFALO

1 960S AND

1 970S, THIS

"INTRODUCTION TO

ONE-SEMESTER COURSE THAT TAUGHT STUDENTS HOW TO TAKE A

PHYSICAL

CASES

BY CLINICAL

LEARNING ABOUT.

SHE'S ALSO GETTING A

GENERAL HOSPITAL.

FOR EXAMPLE, ARE ROUTINELY FOLLOWED

NOW

A

INSTEAD

PRECEPTOR

FULL

OF

YEAR

JUST

COURSE,

WITH

LECTURING

CHALLENGES

HER

TO

HER
TRY

AN

ON

TO

HISTORY AND ADMINISTER A

EMPHASIS

THE

MEDICIN~

CLINfCA- c

ON

CASE-BASED

PATIENTS

EXPLAIN

THEIR

SHE

COMPLETE

LEARNING

EXAMINES,

SYMPTOMS

WAS - A -

AND

KRISTEN'S

AND

ILLNESSES.

HER EARLY EXPERIENCE WITH CASE-BASED LEARNING AND PROBLEM-SOLVING

IS INTENDED TO INTRODUCE HER TO THE SKILLS SHE'LL BE DEPENDING ON IN HER

THIRD AND FOURTH YEARS, TRADITIONALLY KNOWN AS THE "CLINICAL YEARS."

KEN LEVEY, 24, A THIRD-YEAR STUDENT WHO PLANS TO GO INTO OBSTETRICS,

INTRODUCES US TO A TYPICAL DAY IN THOSE "CLINICAL YEARS." KEN, IN THE MIDDLE

OF A

CLERKSHIP AT THE

LUCKY TO

HAVE FOUND

CHILDREN'S

A

HOSPITAL OF

BUFFALO,

FIRST-FLOOR APARTMENT ON

COUNTS

HODGE

HIMSELF

STREET,

WITHIN

STROLLING DISTANCE OF THE HOSPITAL. HIS CLERKSHIP CONSISTS OF THE TRADITIONAL FOUR WEEKS ON A WARD.

IN A RECENT INNOVATION, THE CLERKSHIP INCLUDES TWO ADDITIONAL WEEKS IN CHILDREN'S OUTPATIENT CLINIC.

KEN IS ALSO PART OF ONLY THE THIRD CLASS WHO WILL SERVE A

CLERKSHIP IN

FAMILY MEDICINE.

HEALTH

PRIMARY

CARE

NOW INCLUDE

CARE

AND

SOME

COMMUNITY HEALTH

OF

THE

FUTURE

AMBULATORY

PROBABLY

SETTINGS,

EXPERIENCE IN

CENTERS.

WILL

CLINICS,

SO

DEPEND

MOST

PRIVATE

OF

US'S

HEAVILY

ON

CLERKSHIPS

DOCTORS'

OFFICES

OR

KEN'S TIME IN THESE SETTINGS WILL PREPARE

HIM TO WORK WITH RELATIVELY HEALTHY PATIENTS, IDENTIFY DISEASES EARLIER,

AND EMPHASIZE PREVENTIVE HEALTH CARE. IN HIS FOURTH YEAR, AT LEAST ONE

OF HIS ROTATIONS WILL BE SERVED

ENTIRELY IN AN AMBULATORY SETTING.

THESE NEW ASPECTS OF KEN AND KRISTEN'S EDUCATION ARE PART OF U B'S GENERAL PRACTICE INITIATIVE .

THE SCHOOL IS IMPLEMENTING A NUMBER OF CURRICULUM CHANGES AS IT STRIVES TO GUIDE AT LEAST 50 PERCENT

OF ITS GRADUATES INTO PRIMARY CARE FIELDS.
"THE IDEAL FOUR-YEAR CURRICULUM INTEGRATES ALL ASPECTS OF MEDI-

CINE,

INSTEAD

OF TEACHING THEM

M.D., ASSOCIATE DEAN

TO

TEACH

PROBLEMS,

WANT TO

STUDENTS

INSTEAD

PREPARE

IN ISOLATION,"

SAID

DENNIS A.

FOR CURRICULAR AND ACADEMIC AFFAIRS.

HOW

OF

TO

MERELY

STUDENTS

ACCESS

HOW TO

FOR THE

KNOWLEDGE

MEMORIZE

NATURE

AND

HOW

"WE WANT

TO

INFORMATION.

OF PRACTICE AS

NADLER,

WE

IT IS

SOLVE

ALSO

INFLU-

ENCED BY AMBULATORY CARE AND MANAGED CARE. THESE ARE THE KINDS OF

THINGS THEY'LL NEED TO KNOW AS

r~

0

DOCTORS."

+

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�+- B: 1 1 A.M.
KRISTEN ANDRESEN PACKS
HER LUNCH BEFORE TAKING
OFF FOR A

FULL DAY OF

LECTURES AND CLINICAL
CLASSES.

~ 9

A.M.

1 1 :30 A.M.

TODAY'S PHARMACOLOGY LECTURER , ..JERROLD WINTER ,
PH . D., COVERS A WIDE ARRAY OF TOPICS, INCLUDING
NEUROLEPTICS AND THEIR SIDE EFFECTS, AND DRUG
DEPENDENCE, TOLERANCE AND WITHDRAWAL. WINTER ALSO
WARNS THEM ABOUT ILLICIT RECREATIONAL USE OF THE
THERAPEUTIC DRUGS THEY WILL HAVE EASY ACCESS TO I N
THEIR PROFESSIONAL LIVES. HE CITES THE CASE OF A
DOCTOR WHO DIED AFTER A

LOCAL

SELF-ADMINISTERED OVERDOSE

OF ANESTHETIC. "DOCTORS ARE MORE LIKELY TO GET IN
TROUBLE WITH THESE KINDS OF DRUGS," HE SAYS.

�i- l 1 :40 A.M.
"iHe: ME:DICAL STUDE:NTS'

COMPUTER ROOM IS

C:ROWDe:D DURING THE LUNCH BREAK. FINDING A

~'"Re:e:

TERMINAL,

PRINTs OUT A

KRISTEN QUICKLY EDITS AND

REPORT ON THE HISTORY AND

PHySICAL OF A

PATIENT SHE EXAMINED LAST

We:e:K. THE PAPER IS DUE TO BE HANDED IN THIS

"'-~'"TE:RNOON.

~'"e:w

HER WORK FINISHED, SHE TAKES A

MINUTES TO SURF THROUGH HER E-MAIL.

t 1 2

P.M.

KRISTEN MEETS A

GROUP OF OTHER

SECOND-YEAR STUDENTS IN THE
ATRIUM OF THE NEW BIOMEDICAL
RESEARCH BUILDING TO PLAN
BOARD REVIEW SESSIONS. THEY ARE
CHECKING THROUGH A

LIST OF

PROFESSORS WHO MIGHT BE WILLING
TO GIVE EVENING REVIEW LECTURES.
"IT'S KIND OF TOUGH ON THEMTHEY HAVE TO TAKE THE STUFF
WE'VE BEEN STUDYING OVER THE
PAST YEAR AND SQUEEZE IT ALL
INTO A TWO-HOUR LECTURE,"

KRISTEN POINTS OUT.

t 1 2:30 P.M.
KRISTEN TAKES HER LUNCH TO
A

QUIET CARREL AND EATS

WHILE STUDYING FOR AN
UPCOMING EXAM IN HUMAN
BEHAVIOR.

�t 3:35 P.M. -+
KRISTEN AND THREE CLASSMATES ARRIVE AT BUFFALO
GENERAL HOSPITAL. IN THE
OFFICE OF THEIR PRECEPTOR,
TALAL BAKI, M.D., THEY DON
THE SHORT WHITE COATS THAT
MARK THEM AS STUDENTS.
BAKI DESCRIBES ONE OF HIS
CARDIAC PATIENTS, AND
KRISTEN HAZARDS AN EXPLANATION OF WHAT THE PATIENT'S
SYMPTOMS COULD MEAN AND
HOW THE HEART TROUBLE
MIGHT SHOW UP IN VARIOUS
TESTS.

"YOU HAVE 90 PER-

CENT OF THE ANSWER.

KEEP

GOING, TELL ME THE REST,"
BAKI SAYS, ENCOURAGING HER
TO COMPLETE HER IDEAS.

�4:40 P.M.
KRISTEN READS ALOUD THE CASE
HISTORY SHE PRINTED OUT DURING
HER LUNCH BREAK AND DISCUSSES
IT WITH BAKI.

EVERY TWO WEEKS,

KRISTEN GETS A

CHANCE TO TAKE A

HISTORY AND PERFORM A
ON A

PHYSICAL

BUFFALO GENERAL PATIENT

WHo AGREES TO MEET WITH A
MEDICAL STUDENT.

ON ALTERNATE

WEEKS, SHE PRESENTS THE CASE
HISTORY TO BAKI, WHO SUGGESTS

~UESTIONS

SHE MIGHT HAVE ASKED

THE PATIENT, THEORIES ABOUT WHAT
IS WRONG, OR BETTER WAYS TO
WRITE UP THE REPORT .

_, 6:40 P.M.
KRISTEN HAS FINALLY ARRIVED HOME , WHERE SHE TAKES A
MINUTES TO PLAY WITH HER BLACK LABRADOR ,

SHADOW, AND

FIX DINNER. THEN SHE HEADS TO HER DESK FOR A
STUDYING.
SON I'M

"I

PREFER TO STUDY AT HOME.

I'M A

FEW

NIGHT OF

BOOK PER-

I NEED TO HAVE ALL MY TEXTBOOKS AROUND ME WHEN

STUDYING SO I CAN LOOK THINGS UP."

+

�+-

:20

A.M.

KEN LEVEY RISES EARLY
DURING HIS CLERKSHIP AT
CHILDREN'S HOSPITAL. "I GIVE
MYSELF A

MINIMUM OF FOUR

HOURS OF SLEEP.

I THINK

THAT'S THE ABSOLUTE LEAST
YOU CAN GET BY ON. WHEN
GET SIX I FEEL GREAT."

�6:50 A.M. -+
EARLY MORNING MIST WAFTS BY
LEVEY THIS THURSDAY IN
FEBRUARY AS HE WALKS TO THE
HOSPITAL .

HE'S ON HIS WAY TO

ONE OF THE INFANT WARDS,
WHERE HE'S SERVING A
WEEK CLERKSHIP .

FOUR-

LATER, HE'LL

SPEND ANOTHER TWO WEEKS IN
ONE OF THE HOSPITAL'S
CLINICS TO GET TRAINING IN
AMBULATORY SETTINGS.

1 0:00 A.M. -+
MANY DOCTORS AT
CHILDREN'S HANG TOYS FROM
THEIR STETHOSCOPES OR
WEAR GOOFY TIES WHEN
THEY ' RE TREATING CHILDREN.
"WE'RE TRYING TO DISTRACT
THE KIDS FROM THE THINGS
WE MIGHT HAVE TO DO TO
THEM," ONE PHYSICIAN SAYS.

�•
•
0 •.40 AM

-+

KEN ASKS INTERN THERESA
WEGMAN,

M.D., FOR SOME

ADVICE. THERE'S ALWAYS
THE SOUND OF ONE OR TWO
BABIES WAILING ON THIS
FLOOR, AS DOCTORS AND
NURSES CATCH UP ON
PAPERWORK AND ORDERLIES
PUSH BROOMS AND LAUNDRY
HAMPERS.

~

1 1 A.M.

ATTENDING PHYSICIAN FERDINAND YATES,

M .D .,

HOLDS AN IMPROMPTU LESSON ON DOWN'S
SYNDROME FOR KEN AND HIS FELLOW STUDENTS,
TIM LIESCHING AND LISA MENDONZA. AFTER
CROWDING AROUND THE BED OF A

SMALL DOWN'S

SYNDROME PATIENT SUFFERING FROM A

RESPIRA-

TORY INFECTION, THEY RETREAT TO THE HALLWAY
WHERE YATES TALKS ABOUT THE MEDICAL PROSLEMS OFTEN ASSOCIATED WITH DOWN'S.

~1

1:20 A.M.

KEN TAKES A

FINAL LOOK AT

PATIENTS, BRITTNEY MOREY,
lNG FROM RESPIRATORY

ONE OF HIS TINY
WHO IS RECOVER-

SYNCYTIAL VIRUS !RSV)

PNEUMONIA, ONE OF THE
AILMENTS ON THE FLOOR.

MOST COMMON
BRITTNEY IS DOING

FINE, AND CHECKS OUT LATER
NOON. "WE WANT TO GET HER
BEFORE SHE CATCHES

OUT OF HERE

SOMETHING REALLY BAD

FROM ONE OF THE OTHER
TO BRITTNEY'S MOM,

THAT AFTER·

KIDS,"

KEN EXPLAINS

DAWN SMITH.

�1 2:00

P.M. ~

KEN JOINS OTHER STUDENTS AND
RESIDENTS IN A

CONFERENCE ROOM OFF

THE CAFETERIA FOR A

LUNCHTIME LEC-

TURE BY JEFFREY TUCKER,

M.D.,

THE

MEDICAL DIRECTOR OF THE HOSPITAL'S
POISON CENTER. TUCKER APOLOGIZES
FOR THE SUBJECT-INGESTION OF
CAUSTIC SUBSTANCES.

"IT PROBABLY

ISN'T THE BEST LUNCH TOPIC!"

BUT HIS

LECTURE DOESN'T SEEM TO DULL
ANYONE'S APPETITE.

�/

3:00 P.M. -+
A

.., 7:1

s

P.M.

RADIOLOGY CONFERENCE GIVES
"USUALLY I TAKE THURSDAY

JAMES BACKSTROM , M.D . , THE
NIGHT OFF TO WATCH 'FRIENDS,'

DIRECTOR OF M Rl, THE OPPOR'ER,' AND 'SEINFELD,' BUT
TUNITY TO SHOW STUDENTS HOW

TOMORROW I HAVE TO DO A
TO MAKE DIAGNOSES FROM

PRESENTATION ON
VARIOUS IMAGES .

'FAILURE TO

HE SLAPS A

THRIVE,"'

KEN SAYS. HE

CHEST X-RAY ON THE LIGHT
SPENDS THE EVENING AT THE

TABLE AND CALLS KEN TO THE

HEALTH SCIENCES LIBRARY. +
FRONT OF THE ROOM TO QUIZ
HIM .

KEN SCRUTINIZES THE

IMAGE AND CAN'T FIND ANY
PATHOLOGY .

"ARE YOU TELLING

ME I'D SHOW YOU A
CHEST X-RAY? "

NORMAL

BACKSTROM

ASKS . " NO, YOU WOULDN'T DO
THAT ,"

KEN ANSWERS , PUZZLED .

BUT THAT'S WHAT IT TURNS OUT

TO BE. AFTER THE OTHER
STUDENTS LAUGH , BACKSTROM
POINTS OUT,

"THAT ' S THE

HARDEST THING OF ALL , TO HAVE
THE CONFIDENCE TO SAY ,

'THERE'S NOTHING WRONG

WITH THIS PICTURE.' "

�1916, WHEN HAROLD REIST WaS
finishing his final year at the
University of Buffalo, students
were required to take one year
of arts and sciences courses before entering medical school.
Reist would have spent his first
two years performing dissections
and studying such standard scientific subjects as organic chemistry, physiology and bacteriology. In his third and fourth years,
he would also have studied at
Buffalo General and other hospitals. This photo was taken by
a classmate, Victor Reinstein.

BY

PHOTO: DR. VICTOR REINSTEIN ALBUM ,
UNIVERSITY ARCHIVES . UNIVERSITY AT

BUFFALO

�WITHOUT ITS FACULTY, a school would be nothing

more than an assemblage of buildings and labs~
microscopes and machines. The quality of UB's
School of Medicine and Biomedical Sciences ultimately resides
in the quality of the people who work, teach, and learn here.
It was the innovative, forward-thinking doctors and scientists of the
past, such as Austin Flint, Roswell
Park, and ErnestWitebsky,who made UB a leader in medicine
and research today. And it is the young doctors and scientists
joining UB and its affiliated hospitals who will continue that
tradition well into the 21st century.

I. ~. .:.:I

/..

_f;gJ

. ••::1 we showcase a number of the
·~--

~B

uffalo

In this issue of Buffalo Physician,

lJlJ\

out~

standing young professionals on our

Phys

ician

Spring

199

6

�faculty Some are practitioners who are turning
their everyday experiences in treating disease into
research that will benefit thousands of patients

lg

they will never see. Others are lab scientists whose patience at the bench may
Pay off with undreamed-of drugs and therapies. Some are working on such

)S,

high-profile diseases as AIDS; others focus on problems that rarely touch
)'s

Americans, such as trypanosomiasis.
In this issue, we can profile only a few of the
e.
innovative young men and women who have
Joined our faculty in recent years. We plan to continue the series in future
Issues with articles on new faculty to keep our readers in touch with the
ever-changing medical school.
We hope the articles on the next few

ts

Pages and in coming issues will demonstrate the
range of talent and wide array of specialties that
\!viii continue to provide UB's students with the best in medical education

n,
t~

for years to come.

*

Photographs

J(

by

e

K.C.

Kratt

1

"

f

f

a

1

o

Physician

9

9

6

ED

�in emergency medicine at the Medical College of Pennsylvania. Abrams
is now an assistant professor ofemergency medicine at UB and the associate residency director at ECMC.
Abrams helps train emergency
department residents in fluoroscopy for quick diagnosis of injured
extremities, and in telemedicine for
long-distance communication.
"Ultrasound and fluoroscopy
aren't the kinds of things you'd use
in every situation. But in some cases
they can help you weed out what's
serious from what's not," she says.
"You take a look at an ultrasound
and, boom! you find the bellyache iS
caused by gallstones. That's not an
emergency situation-you tell h1m
he can go home. You st1ck
someone's finger under a fluoroJ.
scope and f1nd out it's not broken.
Fine! That person can go home
instead of waiting around for hours
while you take care of all the gunshot wounds first."
Abrams, who vollltlteered as
an EMT while she was in medical
school, continues to feel strongly
A MAN WALKS INTO an emergency department complaining of about community service. She haS
established a clinic for the homea vague back pain. Hours of tests reveal nothing, and soon the
less at Buffalo's Friends of the N1ght
pain itself disappears. As he dresses to go home, he collapses
People shelter. A volunteer teafl'1
and dies of a ruptured aortic aneurysm.
of nurses, medical students and
doctors visits the shelter two eve"The suspicions we had weren't
Ultrasounds are non-invasive,
nings a month, providing routine
high enough to bring in the radioloquick, cheap and portable, and have
medical care to 15-20 people a
gists and order up an ultrasound.
no side effects. They
night.
Abrams
But if we'd had an ultrasound maare particularly good
hopes to enroll
chine available in the emergency at picturing fluid build"If we'd had an
more volunteers so
department this wouldn't have hapup. All these factors
she can offer the
pened. That's unconscionable that
ultrasound
make them ideal for
services more frehe died," says Barbara J. Abrams,
quick diagnoses in
quently.
"It's a great
machine available
M.D. (known as Bobbie), as she
certain life-threatenopportunity for the
recalls the crisis from her residency
ing situations, such as
in the emergency
medical students
that led to her cunrent career as
aneurysms, ectopic
because they get 3
director of ultrasound education in
department, this
pregnancies, and carchance to take hisErie County Medical Center's emerdiac tamponades.
tories and do physiwouldn't have
gency department.
Her latest research
cal exams and start
Abrams, 34, is bringing ultrashows that tilting a
happened. That's
doing some cofl'1sound technology into emergency trauma patient backmunity service. The
departments around the country. In
unconscionable
wards in the T renpatients are also Incourses for the American College
delenburg position
credibly
appreciathat he died."
of Emergency Physicians, she trains
can help doctors ditive."
emergency physicians in ultrasound
agnose injuries that
Abrams orgause, develops protocols to help
involve intraperitonized a similar cliniC
them decide when the procedure is
neal fluid build-up.
atherlastpostin Philadelphia "I saidt0
appropriate, and tailors diagnostic
Abrams received her M.D. from
myselfthat wherever I go, ifthey need
techniques for traumas.
Brown University and did a residency
a homeless clinic, I'll do it"
-:J.A

Barba r a

Ab r ams ,

M. D .

Adding to the ER's
Diagnostic Arsenal

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9

�Bumpers ,

l .

Harvey

M. D .

Ji~s

:rJ-

doctors and patients are slow to
recognize the waming signs of cancer when they appear in younger
patients, so the disease in these
patients progresses further before it

Creating New Models
of Cancer in Mice
HARVEY

l.

BUMPERS,

M.D.,

HAS BEEN SO BUSY

making breakthroughs

Vvith animal models of cancer that he hasn't had time to begin a
set of experiments he has been imagining for years-experiments
;e
~s

:'s
IS.

,d
is
Hl

rn

:k

that he believes may hold the key to cancer.
U .Bumpers, 40, a graduate of the
n1versity of Rochester School of
Medicine, completed his surgical
Internship and residency at SUNY
Stonybrook, where he was chief
~esident. He held surgical oncology
ellowships at SUNY Stonybrook
and Roswell Park Cancer Institute.
An
·
U ass1stant
prefessor of surgery at
EB, he is an attending surgeon at
[; CMe, the VA medical center, Bufpalo General Hospital, and Roswell

ark

as
al
;ly
3.5

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Bumpers has succeeded in growIng human colon polyps in severe
combined immunodeficient (SCI D)
l'l'1lce. He has also implanted cancerous tissue in such a way that it
con·
p Slstently metastasizes to the liver.
revious researchers treated cancerou s t.1ssue w1th
.
enzymes or
chem·leas
I 1n
. order to get it to grow
lf'lb sites under the skin or in the
ae do men. Bumpers found, howVer, that pieces of solid tumor
no special manipulation to
needed
g
row·
In
the
mice's gonad fat pads1
~ fact, he believes that the tumors
· ••etastas1ze
· because their natural
st
n ructure and cell components are
ot altered.

perfonm genetic studies to compare
precancerous polyps with cancer, and
premetastatic cancers with metastatic
ones. He also hopes to evaluate
treatments in the mice with cancer.
"This is all working so well, I
haven't had time to get started on
what I I 00 percent believe is the
answer to cancer," Bumpers says. "I
think the answer will be found in the
adhesion proteins in cell membranes.
But I have some other work to do
before I can look into that."
Bumpers has also done epidemiological studies of fisk factors in
colo rectal cancer and breast cancer.
In both, he found that younger patients had worse survival rates than
older ones. He believes that both

is diagnosed.
A major in the U.S. Anmy Reserves, Bumpers recently created a
unique reservist training program at
the Buffalo VA medical center. He
and several nurses in the Reserves
arranged to perfonm surgery on Saturdays at the VA to fulfill the requirements of their drill duty. The
arrangement allows reservists who
are surgical scrub technicians to maintain their training by regularly helping in the surgery. It has also helped
the VA reduce the length of time
patients wait for non-emergency
surgery.
Bumpers also participates in public education on cancer through radio shows, workshops, and mailings
organized by churches. "I feel strongly
that if there is a possible solution,
you should do your best to tell
people what it is," he says. "Otherwise, they hear something on the
news about cancer, and don't do
anything about it."
-J.A.

*

L.

(I)

u
c:

8 In another breakthrough,
t Umpers has used similartechniques

a-

s~lgow human breast cancer in
able t mice. "No one has ever been
0 grow human breast cancer
lf'l
,•. any animal before" he says "and
•ve d '
'
'
th
on t know exactly what it is
that prevents it from growing. I
lf'lklt'sb
Call
ecause breast cancertypi" y has a lot of fibrous tissue and
••Ot V
ery many cells."
· new exPe .His sue cess ·1n creat1ng
ca nmental models for two kinds of
Ofncer has provided him with a lot
Pr ·
OJects to work on. He plans to

0

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M chaeI

Ca I

M. D .

g ur

Boosting the Immune
System with lnterleukin-2
MICHAEL

A

CALIGIURI, M.D .,

is researching new approaches to

preventing cancer and controlling AIDS via the immune system.
He is also part of an unusual team that develops treatments
from the concept stage all the way through the laboratory
bench to the patient's bedside.
"It's incredibly satisfying to see
our own observations translated
into a treatment for a patient," says
Caligiuri, 40, who is based at Roswell
Park Cancer Institute.
Caligiuri holds an M.D. from
Stanford University and did his internship and residency at Harvard
Medical School in Brigham and
Women's Hospital in Boston. He
did a fellowship in medicine at
Harvard, and fellowships in oncology
and bone marrow transplantation
at the Dana-Farber Cancer Institute. Now a tenured associate professor of medicine at UB, he is a
member of the department of hematologic oncology and bone marrow transplants.
Caligiuri and colleagues including Zale Bernstein, M.D., recently
studied a small sample ofHIV-positive patients and found that daily
injections of interleukin-2 substantially boosted levels of natural killer
cells, one of the types of immune
cells that is decimated by the virus.
As a result, none of the I 0 patients
suffered opportunistic infections
during the 90-day treatment period. The interleukins are part of a
class of honmones called cytokines
that regulate the growth of certain
immune cells. According to Caligiuri,
this was the first cytokine trial in
AIDS patients.
The findings raise the possibility
that AIDS could be controlled with
daily self-administered injections.
The injections would boost the
immune system to fight off fatal
opportunistic infections, such as
pneumonia and Kaposi's sarcoma.
"Like diabetes, this would be hormone replacement therapy," says

ED

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Caligiuri, "but instead of sex hormones, we're working with the
honmones of the immune system."
Caligiuri is also studying the relationship between compromised
immune systems and cancer. People
with AIDS and other immune system problems suffer I 00 to I ,000
times as many lymphomas and sarcomas as the general population
does.
In research on severe combined
immunodeficient (SCID) mice,
Caligiuri and his colleagues have
found that low doses ofinterleukin2 prevent certain lymphomas. The
mice are bred to have severely
inadequate immune systems, and

h

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s

can be induced to develop a human-like immune system with injections of lymphocytes from human donors. Humans who are
seropositive for Epstein-Barr virus
are at high risk of a certain fatal
lymphoma; mice who are injected
with samples from these humans
will be at risk for the same cancer.
But with surprisingly small daily doses
of interleukin-2, Caligiuri says, the
mice were protected from the cancer.
Caligiuri also led an international
team that recently discovered a
genetic defect linked with one common fonm of leukemia, acute myeloid leukemia. The defect was discovered on chromosome I I , and it
was already known that many patients with acute myeloid leukem1a
have three copies of chromosome
I I. The researchers, who include
UB oncology division chief Clara
Bloomfield, M.D., say it is the first
known molecular defect associated
with a trisomy.
Caligiuri predicts that more
molecular defects will be identified
and linked with different cancers,
opening the way to gene therapies.
Much of the research on leukemia.
he says, may be performed at
Roswell Park, which runs the world's
largest leukemia bank.
-J.A.

*

p

n

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�J1-

J-

·e
JS

al
,d

~s

Michael G. Ca t y' M. D.
al

a
l-

ysit
ala
1e
le

Teaching
Generalists as
a Specialist

ra

st
~d

tDUCATING GENERAL PRACTITIONERS IS A CHALLENGE

for special-

ists like Michael G . Caty, M. D ., a pediatric surgeon at the
Children's Hospital of Buffalo .
-s.
~s.

a.
at
l's

t....

"To provide them w1th a
rTieaningful education, we apply
our day-to-day work to their
needs," Caty says.
. Some of his students are pediatnc surgery fellows who have already
~eceived general surgerytraining and
ave chosen pediatric surgery as
thew subspecialty. These students
need to be taught very specific details of pediatric surgery that will
enable them to sue~eed in their newfield.
Ut Caty also teaches
general surgery residents, the majority of
'Nhom aren't likely to
go on to pediatric sur~ery. These students,
e explains, need to
1
earn basic surgery
Pnnoples and only as
much about pediatric
surgery techn1ques
.
th
as
eymayneed in their
Practice.
th As the director of
C eclin1cal clerkship at
hildren's Hospital
Caty also trains med 1 ~
cal
h students who
aven't yet decided on

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their future. They will leam enough
about pediatric surgery to help them
decide when to refer a patient to a
specialist, and may also spend time in
the division's clinic, where they'll see
a variety of patients.
"You can be a role model and
a mentor even being in a different
field," Caty says.
Caty, 37, earned his M.D. from
the University of Massachusetts, and
did a general surgery
residency at University of Michigan Hospitals, where he
served as admlnistrative chief resident.
He was a clinical fellow in surgery at
Harvard Medical
School in the Chiidren's Hospital of
Boston.
H1s field of pediatric surgery has
given Caty a chance
to develop a wide
range of expertise,
because although he
specializes in one
population,
he
doesn't limit himself

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to a single type of surgery. One of
his specialties is laparoscopic
splenectomies, performed on patients with spherocytosis. Because
the disorder is hereditary. many of
his patients' parents also underwent splenectomy operations when
they were young.
"The parents vividly recall having big incisions and being in the
hospital for a month, and they're
very appreciative when their
children can have it done with
laparoscopy," Caty says.
Caty's research has centered
on understanding and preventing
organ damage caused by ischemia
and reperfusion. lschemia/reperfusion damage is often linked with
necrotizing enterocolitis, an intestinal infection among premature newborns. lschemia/reperfusion research can also be applied to transplant surgery, because organs can
easily be damaged by the interruption in blood flow that occurs during a transplant.
Caty's recent experiments on
the intestine indicate that histamine
produced by the body during
ischemia/reperfusion events may
contribute to organ damage. His
research suggests that drug therapy
against histamine could be an effective treatment to help prevent the
-J.A.
damage.

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Going after Brain Tumors
from a New Direction
KEVIN

GiBBONS ,

M.D.,

IS

TAKING

NEW APPROACHES

to

neurosurgery and head-injury management.
Gibbons, 35, is the director of
Millard Fillmore's neurosurgical intensive care unit. He holds an M.D.
from Albany Medical College and
did his internship and residency at
UB. He also did a fellowship in
surgical critical care at UB.
Gibbons specializes in skull-base
neurosurgery, particularly in novel
exposure techniques for internal
aneurysms, blood vessel malformations, and tumors once thought
to be unresectable. These are often benign tumors; that is, in a
different part of the body their

slow growth and lack of metastases
would pose few problems for the
patient. But when they are situated
deep within the brain, or in bone
separating the brain from the face,
their pressure on the brain, the
cranial nerves, or the cerebrospinal
fluid leads to debilitating symptoms
or death.
Traditionally, surgeons would
open up a section of the cranium
and push or pull aside the healthy
brain to reach at least part of the
tumor. But Gibbons says this procedure is often not successful in

exposing the entire tumor and can
injure healthy tissue, leading to
complications such as hemorrhage.
infection, stroke, and spinal fluid
leakage. Instead, he and colleagues
at Millard Fillmore and Roswell Park
are entering the brain at the base
of the skull or through the face.
Using these newer approaches, surgeons are more likely to reach the
entire tumor without disturbing or
injuring the healthy parts of the
brain.
Gibbons twice a year teaches 3
. I
national course on neurosurglca
critical care sponsored by the
American Association of Neurological Surgeons.
He is working to popularize a
change in treatment of traumatiC
head injuries and aneurysms. Doctors typically treat strokes and an.
ve
eurysms by working to 1mpro
blood flow to the brain. However.
after a traumatic head injury, they'
focus on controlling brain swelling
by administering diuretics or other
medications. According to Gibbons.
these measures don't work for very"
long, forcing repeated treatment
after a day or so.
The new guidelines recornmend increasing blood flow and
perfusion to the injured brain: regardless of what caused the InJury'·
Gibbons recommends ventilating
·
patients and increasmg
cardiaC
output through drugs to ·lncrea se
blood flow.
"The swelling problems may'
be worse in the short term, but 1n
the long term, they improve more
rapidly," he explains. "It's the sarne
experience with other organs whefl
they are inJ·ured-they do better
· st
with better blood flow. It has JU
taken us a while to realize that the
brain should be treated the sarne
way."
11
Gibbons was also a part of
team that pioneered a new pal~
treatment in surgery for rupture
discs. He and his colleagues lrl'
serted a naturally degradable mor.
1 s ite
phine sponge into the surglca
and found that it provided longterm pain control.
-J.A·

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�e
r

Carlos

Jaen

Roberto

M.D., Ph.D.

'

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:r

s.

1

,t

laking the Pulse of a
Whole Community
''F AMILY

PRACTICE IS LIKE TAKING CARE OF FRIENDS,"

says Carlos

1\oberto Jaen, M.D., Ph.D. "You have a chance to be close to
People at so many important times in their lives. You form a
Partnership with them to improve their health or their function .
It's a challenge intellectually and at the level of your heart."

fil
ain
-ed
inor;ite
ngJ.A·

th Jaen has made many friends in
l e Poor communities of Buffalo's
tower West Side, where he prac~ces at the Niagara Family Health
lJ enter and directs UB's Center for
J ~an Research in Primary Care.
~n, 39, earned . his M.D. and a
.D. 1n ep1dem1ology from UB,
. ~,amlly
. pract'and did h.IS res1.d ency 1n
~~e at University Hospitals of
feveland. An assistant professor
0 both family medicine and social
:nd preventive medicine, Jaen
Perves on the New York State
t' Ubi'IC Health Council and the na~onal Agency for Health Care
ohcy and Research.
Jaen has gained special insight

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into the largely Puerto Rican community of the Lower West Side by
supervising a comprehensive health
survey of the area.
The survey, conducted in 1993
and 1994, found high levels of
asthma, diabetes, heart disease, hypertension, and other chronic conditions. The researchers also found
high numbers ofsmokers-47 percent of the men and 32 percent of
the women, compared with a national average of about 23 percent.
In addition, they found that barriers
such as language, distance, and lack
of health insurance often prevented
families from getting adequate
health care. The researchers also

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charted beliefs about HIV, use of
preventive services, drug use, and
experiences with crime.
"One reason we were able to
get such a high response rate is that
our people were very persistent.
They wouldn't take 'no' for an answer," he says.
His group shared the research
with community groups, who in
turn shared their own insights and
joined the efforts to solve the problems. "The community became
empowered," he says.
The survey has also spun off
new projects for jaen and many of
his students. Jaen has won a grant
to reinterview the asthmatics in
the study population. "Mortality
from asthma has been increasing
in poor urban communities over
the past I0 years. Is it environmental exposure? Is it tobacco smoke?
Is it lack of knowledge? Is it poverty? What is it that is causing this
problem?" he asks.
Jaen also writes columns for Panorama Hispano, a Spanish-language
monthly that circulates in western
New York. "I pride myself on my
ability to make things that are very
complex simple. I do that when I do
direct patient education in my office,
but also in a more public way when
I do it in print," he says. "It makes me
feel good when a patient comes into
my office and says, 'I read your
article about smoking.' It's a way of
reaching more people than just the
ones I can see in my office."
One ofhis anti-smoking projects
is a survey of how cigarette advertising and promotions are tailored
to the inner city. Jaen says that
although tobacco companies spent
$6 billion on advertising last year,
he is not intimidated by their
strength.
"I follow in the tradition of
Don Quixote, I suppose. I have a
picture of some windmills in my
office that my mother got me
when she went to Holland, and
they inspire me. I just keep working in my circle of influence and
see what happens. I think we have
-J.A.
right on our side.''

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M

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task than they may have been Jed to
believe."
t
In Canada, James points ou '
about 50 percent of me d .ICa1 stu-

Specializing in Everything
DAVID jAMES, M.D., is working to reintroduce a concept as old

as professional medicine, and as new as 1990s health-care
reform: the family doctor.
"My father's family doctor took
out his tonsils on the kitchen table,
and amputated mygreat-uncle'sanm
on that same kitchen table," James
says. "The family doctor looked after you from birth and the cradle to
the grave."
A Toronto native, James, 37,
earned his M.D. from the University
ofToronto. In the Canadian system,
James says, family practitioners are
trained in all primary care areasobstetrics, pediatrics, and emergency
and internal medicine. In his solo
practice in a Toronto suburb, he
saw patients in his office for about
44 hours a week, spent another 25
hours in emergency practice, and
delivered two to four babies a week.
"You're expected to have almost specialist knowledge in every
area," James says.
As an assistant professor of fam-

dents become family practloners·
d
11
Underthe country's publicly funde
.
health plans, pat1ents
can 't get free
. I.1st un less theY
care from a spec1a
are referred by their fam1 IYd0 ctor.
. es
"The family doctor superviS
their care, acts as a curator. The
.
amount of money .It sav es iS
remarkable," he says.
d
James welcomes the pu brIC an
.
private pressures t hat are driving
d
this country towar
. eon
agreaterre I1anc
.
general practl'tiO'

ily medicine and the new medical
director of Deaconess Center's family medicine center, James hopes to
train a new generation of U.S. doctors in the same wide
range of knowledge.
He teaches family
medicine, low-risk
obstetrics, pediatrics,
In Canada, about
emergency medicine,
and a wide range of
other procedures.
50 percent of
James is also an attending physician at
medical students
Deaconess and in
Buffalo General's
emergency and obbecome family
stetrics departments.
"Part of my job is to
practitioners.
show students that
being a family physician is a much more
broad, demanding

ners. "General prac~
tice is not seen a
being glamorous, the
hours are irregular.
and you don't rnak~
the same kind o
dough, so students
tend to go into sp ecialties. But I ber1e ve0
that in five to 1.
years everybody iS
going to earn a bout
the same amounpS
the health-care rn ar-

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Shahrokh

Ph. D.

M. D.,

Khan

Fighting Blindness through
Surgery and Research
SHAHROKH

C. KHANI, M.D., PH.D., woRKS ON RETINAL degenerative

disorders on two levels- the operating table and the laboratory bench. His primary research interest is in retinal gene
therapy; currently, he is engaged in a search for the key to
retinitis pigmentosa.
Khani, 33, eamed his M.D. and a
Ph.D. 1n biological chemistry from
the University of Michigan. He was
an ·
1ntem at Saint Joseph Mercy
Nosp1tal in Ann Arbor, Mich., and
~ a residency in ophthalmology at
ash1ngton University. He also did
fellowships at Harvard Medical
~hool and the Medical College of
ISconsin before coming to UB.
An assistant professor of ophthalmology and biochemistry, Khani
teaches residents and biochemistry
graduate students and is UB's director of retina services.
Retinitis pigmentosa is a congenital disorder that interferes with
the eye's ability to adaptto light and
da.L
.
.
Ioss o f
'"' caus1ng
progress1ve

vision that can range from night blindness to total blindness. In young patients, whose only symptom may be
night blindness, an electroretinogram
can detect the functional problems
that signal more severe problems to
come. The disorder is also characterized by, and named for, the presence
of extra, clumped pigmentation in
the ret1na.
Because the enzyme rhodopsin
kinase helps photoreceptors to adapt
to light by catalyzing the phosphorylation of the visual pigment rhodopsin, Khani believes that a mutation in
rhodopsin kinase may be responsible
for retinitis pigmentosa. As an initial,
but substantial, step toward identifying the defect, Khani has succeeded

in isolating and cloning the gene and
identifying several mutations.
Next, Khani's research team w ill
try to express the mutant proteins in
bacteria or cell cultures and analyze
them, then introduce the mutation
into a mouse and perform electroretinograms to see what effect it
has on retinal response.
"Retinal gene therapy is in its
infancy. 1 th ink that more and more
work wi ll be done in this area," says
Khani.
Although retinitis pigmentosa affects only a small number of people ,
Khani believes that the techniques
he is establishing will have widespread applications.
''I'd like to find more genes
responsible fo r retinal degenerative
disorders-particularly age-related
macular degeneration, which is the
cause of blindness in about 2.2 percent of the population," he says.
Even after genetic defects are
identified In retinal degenerative
disorders, the re are many hurd les
that need to be overcome before
gene therapy can be establ ished
as routine, Khani explams. Unlike
the cornea, the retina is re latively
difficu lt to infect with the viruses
that could be used to transfer
genes, he says. Also, when researchers have succeeded In transferring genes to the retina, they
have been d isappointed to find
that the new genes are not functionally expressed.
Because functional gene therapy
is so far in the future, there is still
plenty of demand for the retinal repairs Khani performs In the operating
rooms at Erie County Med1cal Center and Millard Fillmore Hospital. As
a vitreoretinal surgeon, Khani uses
Iase r treatment to correct diabetic
.
retinopathy. He is also engaged In
clinical trials on the use of high-density periluorocarbon liquids to reattach detached retinas in complex
cases. Khani's trials compare the usefulness oftwo ofthe fluids, periluoron-octane and periluoro-n-octyl bromide. The high-density liquids are
injected into the eye, where they
settle under the fluid in the eye and
gently press the retina into its proper
place, stabilizing it while scar tissue is
removed by lasers. The liquids can
easily be removed after the opera- J.A.
tion.

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S t e nhorn,

H.

M. D .

neonatology department Nitric oxide, which is naturally produced in
endothelial cells, was being used for
the first time to relax the smooth
muscle layer around the blood vessel, and enable an oxygen-deprived
baby to breathe. For infants that do
not respond to medication, she
brought her expertise in heart-lung
bypass surgery, which she calls a
"safety net" and a "last-ditch effort." The complicated procedure
of handing an infant's respiratory
and cardiac functions over to machines for five to seven days requires 24-hour vigilance from two
professionals, but gets positive
results.

Saving Newborns Who
Can't Breathe
RoBIN

H.

STEINHORN,

M.D.,

HAs MADE A CAREER

out of saving

newborn infants who are literally blue from lack of oxygen. The
window sill in her office at the Children's Hospital of Buffalo is
filled with pictures of her now-thriving patients.
Steinhom is fascinated by the
moment when a baby takes its first
breath of air. "Never at any time in
anybody's life is there such a dramatic change with such rapidity,"
she says. In more than I in I,000 live
births, that first breath can't oxygenate the baby's blood, and the infant
is diagnosed with persistent pulmonary hypertension. These are the
babies who are sick enough to qualify
for the specialized treatment
Steinhom can offer as medical director of Extracorporeal Life Support Services at Children's Hospital.
Babies with persistent pulmonary

hypertension are brought to
Children's via helicopter from all
over the state for treatment.
Steinhom, 39, got her M.D. from
Washington University and did a
residency in obstetrics and gynecology at the Bames Hospital Group.
She then swrtched fields, completing
a resrdency rn pediatrics at the University of Minnesota, where she
became an assistant professor of
pediatrics.

Steinhom also helped develop
a program to train doctors, nurses,
and technicians in heart-lung bypass
while she was at the Variety Club
Children's Hospital at the University ofMinnesota Hospital and Clinic
in 1986. She brought the program
to Children's Hospital of Buffalo.
Her current area of research is
cyclic guanosine monophosphate
(cyclic GMP), a naturally occurring
substance that relaxes blood vessels and works in concert with
nitric oxide. She hopes that an
understanding of how the cyclic
GMP system develops naturally will
help explain why it fails in some
babies.

Steinhom came to Buffalo four
years ago because she was interested in the pioneering work being
done wrth nrtnc oxide in the hospital's

Steinhom prescribes passion for
one's work. "Have some real excitement about what you are doing," she advises medical students.
"I never go to the nursery without
thinking about what I am doing in
the lab, and I never go to the lab
without thinking about the nursery."

•

She recalls her false start in obstetrics. ''After my first year of training I realized that I was more interested in the babies than the mothers." She was particularly intrigued
by the blood vessels in infants' lungs.
which can be manipulated in anumber of ways after they are bom. "It
aroused the scientist in me," she
says. Steinhom calls the examination of blood vessels and cyclic
GMP her main contribution to medicine, and hopes the future holds not
only a cure for persistent pulmonary hypertension but also a way to
prevent it

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Stephen

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Diagnosing Bacteremia in
Febrile Children
UP TO

·e

IS

PERCENT OF THE CHILDREN

who come to a pediatric

emergency department present with nothing more than a
fever. But their diagnosis can be as innocuous as a cold, or as
serious as meningitis.

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Polymerase chain reaction (PCR)
technology, which has
been used for years in
laboratories to replicate DNA and create
samples large enough
to identify, will soon
move into the hospital and become a
speedy alternative to
cultures, Teach predicts. PCR could identify a disease in 3 to 6
hours. "It will begin the
molecular triage of
sepsis," he says.
PCR diagnosis will
improve treatment by

Doctors must quickly determine
Which of the feverish children are
suffenng from occult bacteremia,
the bacterial infection in the blood
that precedes and can blossom into
a full-fiedged disease, such as a
urinary tract infection or meningitis.
Current culture techniques,
wh1ch rely on watching the growth
of bacterial colonies from a blood
sample, can take from I 2 to 72
hours to diagnose bacteremia. Children who appear to be at risk are
not only started on antibiotics but
often hospitalized for the entire
time 1t takes for the culture to
Prov1de an answer. "The approach
to that complaint hasn't really
Changed in years, and I believe it is
about to change," says pediatrician
Stephen Teach, M.D., a clinical asSistant 1n pediatrics who specializes
1n ped1atric emergency medicine at
the Children's Hospital of Buffalo.
Teach, 40, earned an M.D. from
Narvard University and a master's
degree in public health from the
University of California at Berkeley.
l-ie did a residency in pediatrics at
Children's Hospital of Boston, and
Vvas a clinical fellow in pediatrics at
Narvard Medical School before
com1ngto UB as an assistant professor of pediatrics and emergency
mediCine.

accurately identifying the small percentage of feverish children who are
suffering from a serious illness. It will
also help hospitals cut down on
costs by shortening the length of
inpatient stay. Many hospitals are
already building "short-stay" units
designed for treatment ranging from
a few hours to a full day.
PCR will be particularly valuable
in identifying bacteremia because
the various organisms that cause
bacteremia are well known. "You
can't just screen for everything. You
have to know what infections are
epidemiologically
likely to be present
in this patient, and
for bacteremia those
bacteria are well described."
PCR is already
used at Children's
Hospital to identify
herpes, pertussis,
HIV, Lyme disease,
and some other diseases, Teach notes.
"This will just be an
expansion of an existing technology,"
he says. 'k - J.A.

Teach's research into fever
among children has shown how
~ifficult bacteremia is to identify.
or example, in a 1995 paper, he
demonstrated that one of the standard observation scales for classifying
fevers 1s not very useful for children
under three years old.
"This is where I think we're
go 1ng to see the world of molecular
d1agn ost1cs
· enter 1nto
.
the world of
ambulatory pediatrics," Teach says.

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•

�their livestock, so that even if people
do settle there, they can't support
themselves. And then it kills the
people as well," Williams says.
T rypanosomes have a number
of unique adaptations that make
them particularly tough to kill or
immunize against. They easily elude
the human immune system because
they change the glycoproteins. in
their coat as antibodies recogntze
them. The constantly changing coat
makes it next to impossible for the
immune system to recognize them
as invaders.

w

No reen

I I

T rypanosomes also have an
unusual genetic structure. The
organism's genes are shorter than
needed, so in order to express
functional proteins, the trypanosome edits its own genes, spltctng
togetherthe necessary components.

a ms ,

p h. D.

Williamsisfocusingherresteabr~

SLEEPING SICKNESS IS A DEVASTATING DISEASE endemic to Africa and

on the organism's energy me a .
Iism, which is also unusual. Leamtng
more about what distinguishes trypanosomes' biochemistry from that
of the cattle and humans it infects
could lead to a drug that will target
· h no efand kill the protozoan wtt

Battling Parasites with
Molecular Biology
South America that saps strength and induces fatal comas in
people and cattle. The key to fighting it may be to block the
metabolism of the tricky parasite that causes it, according to
microbiologist Noreen Williams, Ph.D.
"It gives me some satisfaction to
be working on this disease," she
says. "It's a disease of developing
countries, and so it hasn't been the
focus of much research. The
countries where it's endemic don't
have many resources, but that
doesn't make them any less

cycle in the tsetse fly. It infects the
insect's salivary glands and is injected
into cows, antelope, or people as the
fly bites them. The trypanosome
thrives first in the bloodstream,
then-over months or years-invades the lymph nodes, the heart,
and the central nervous system. If

important."
Williams, 40, holds a Ph.D. in
biochemistry and molecular bioiogy from New York University. She
did postdoctoral work at The johns
Hopkins University and was an assistant professorwith the Uniformed
Services University of the Health
Sciences before coming to UB in
1992. An assistant professor of microbiology, Williams is also the di-

quickly identified, the disease can be
cured by drugs. If not treated before
it reaches the central nervous system, sleeping sickness leads to headaches, confusion, lassitude, coma, and
death. An East African strain moves
more quickly, often killing through
congestiveheartfailurewithinweeks
or months. A closely related illness in
South and Central America is called
Chagas' disease.

rector for microbial genetics and

"It's a severe problem in devel-

physiology.
The parasite that causes sleeping
sickness, trypanosoma brucei, is a
protozoan that lives part of its life

oping countries. The tsetse fly breeds
in water, meaning it lives in the parts
of a country that would be good
places for people to live. But it kills

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feet on the host.
..
1
"We're looking at the cnttca
't to
enzymes that are necessary ~,or 1
survive. If you knock them out, you 'd
knock out the organism," she says.
Williams is particularly interested tn
an ATP synthase that helps the
trypanosome generate A TP for.''tS
energy requirements. Compltcattng
the research is the fact that trypa. rn
nosomes change their metabo 1IS
as they move between their insect
and mammalian hosts. In a recent
paper, Williams and her colleague~
identified an inhibitor pepttde tho
apparently helps regulate ATPase
function.
"Modern biochemical approaches are new to parasitolog}'•
·
1tg ht
and they've helped .1t JUmp
years in the past I 0 years," she says~
"It's a microcosm of what '.: hap
pening in science in general.
. Williams is also entering into t~
new collaboration to study plan
that are chosen-apparently for
medicinal purposes- by animals like
chimpanzees and gonl.I as. Sh e Plans
to help test substances firom thef
plants on the "tryps" in the hopes 0
finding new leads to a cure. * -J.A·

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�"The real lady is as much out of
place in the practice of medicine
as in a regiment of dragoons. "
So ran an editorial in the Buffalo
Medicaljournal in 1857. But by
1880, l3 regular medical colleges around the country admitted women. The University of
Buffalo was one of them, having
graduated its first woman, Mary
Blair Moody, i.n 1876. By 1912,
when these medical students
were photographed in the library, it was not uncommon for
women to make up about 10
percent ofUniversity ofBuffalo's
graduating class.
PHOTO : UNIVERSITY ARCHIVES , UNIVERSITY
AT BUFFALO

/cfcf:?l
The university was also progressive in admitting black students.
Early records do not list race, but a
number of black students are
known to have graduated in the
19th century. joseph Robert Love,
class of 1880, is believed to have
been the first. The second,
Cornelius Nathaniel Dorsette, was
rejected by the University Medical
College of New York City because
of his race before being accepted to
the University of Buffalo. Pictured
here wi.th his class in 1882, Dorsette
became Booker T. Washington's
doctor and a founder of the National Medical Association.
PHOTO: UNIVERSITY ARCHIVES , UNIVERSITY AT
BUFFALO

�Medicine o t
WHAT DOES THE FUTURE HOLD FOR MEDICINE? A procedure to lengthen life
indefinitely?The eradication of disease? Genetic manipulation to create
the perfect human being?
Members of the UB community don't think so. Instead, they
believe the next 50 years will bring little change in disease, and
continuous progress in technology and treatments. What will change
quickly and dramatically, they predict, is the profession of medicine as
it is buffeted by social, political, and economic forces.
Their speculations, which are presented on the following pages,
were summed up by Gerald Logue, M.D., chief of staff at the Buffalo
VA medical center.
"If you look at the last 50 years in medicine, we've made
enormous advances that you couldn't possibly have predicted. That's
probably going to happen in the next 50 years as well.
"Nevertheless, the diseases will always be there. We may alter

.
.
.
.

some presentations, and there may be a few new viruses. But people

0

have a finite life span. Even if we eliminated cancer, it wouldn't extend

0

life span very much.There are factors that are age-related that aren't
disease-related.

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"Violence and war will probably still cause trauma and longlasting effects," he concluded."We're much more likely to look back in
50 years and be impressed with man's inhumanity to man than with
nature's inhumanity to man."
The top worry for all our respondents was the economy of
health care-how it will be affected by spiraling costs, managed care,
changes in Medicaid and Medicare, and politically driven systemic
reform. Almost all of our experts predicted some type of universal
health-care system, either public or private, in the near fui:tJre.Thomas
Rosenthal, M.D., chairman of UB's Department of Family Medicine,

1

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�uture

(

PHOTOS

BY

FRANK

CESARIO

)

was optimistic that economic pressures would result
in some improvements in care-a return to
family medicine, for instance. But many of our
respondents had more worries than hopes,
fearing losses in doctors' traditional autonomy
and in quality of care. Susan Regan, a
prominent health-care attorney, summed
up the topic of health-care financing for
us, also touching on issues of market
competition and tax reform.
Another topic of concern was drug resistance in disease-causing organisms. jerome
Schentag, Pharm. D., provided hope for the future in his discussion of the issue, pointing out
that while discovering new drugs will help, changing the way doctors use existing drugs may
do even more to fight the problem.
Two bright views of the future were provided by David Ellis, M.D., who discussed the
burgeoning field oftelemedicine,andAian Lockwood, M.D., who talked about the emerging
possibilities of modern imaging technology. Both felt that their specialties have the potential
to bring progress to medicine: imaging by discovering new information, and telemedicine
by disseminating information.
james Nolan, M.D., speculating on the future of medical training,thought that greater
demand for primary care physicians may lead to a new system in which almost all medical
school graduates enter generalist residencies. He also speculated that the cost of residency
training may in the future be shouldered by the public sector:

f

Medical ethics specialist Stephen Wear, Ph.D., offered a thoughtful look at the moral

.,

aspects of medicine. He believes that it is poor communication between doctors and
patients that causes many of today's ethical tussles. Although these may melt away as
doctors change their attitudes, he anticipates that there will always be new problems. Finally,

5

Wear wasn't the only member of our panel who was concerned that cost considerations,
rather than medical ones, might begin to constrain care.

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GERALD L . LOGUE , M . D . , ON MEDICINE

.

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The future will
change how
•

practiced

IS
DISEASES OF THE FUTURE WON'T BE

appreciably different from
today's, but the practice of medicine will change radically, accordingto Dr. Gerald L. Logue's
peek into the crystal ball.
Logue says that because recent research has brought breakthroughs in understanding the
genetic basis of cancer. breakthroughs in cancer therapy may
be only a few years away. "We're
going to see a tremendous reaping of benefits ofthat research in
the next five to I 0 years.'' However, advances in treating other
problems, such as cardiovascular
disease, substance abuse, and environmentally triggered illnesses,
will probably be incremental
ratherthan revolutionary. 'We'll
just keep chipping away." says
Logue, chief of staff at the Buffalo
VA medical center.
What will change more radically. Logue predicts, is the way
medicine is practiced. Burgeoning health-care costs and politically
driven systemic reform will change how doctors pract1ce mediCine,
and who pays for it. Obvious changes surround1ng the advent of
managed care include more ambulatory care, and more control by
payers and less by doctors. Logue also predicts greater cooperation
between doctors and other health professionals, such as nurse
practitioners, nurse-midwives, and physician assistants.
primary care can be delivered by these other professionals, he notes.
He also predicts a change in the way doctors use the tools
of their trade. "We are slaves to our technology. Our technology is way beyond our ethics, or our methods of using it," he
says. Because life-prolongmg technology IS available, doctors
and families tend to use it on patients even when the patient's
uality of life is poor and there's no hope of recovery. "It isn't
!e right thing to do," Logue insists. "We're at the mercy of our

·::ome

technology-we love it, we
idolize it, we worship it."
Logue hopes that this will
change as doctors become more
educated, and as more patients
are urged to appoint health-care
proxies and make advance-care
directives. The change will be
driven not only by concern for
skyrocketing costs but also by a
desire for better and more
rational health care. "We will
have to tum around our technology-driven health-care system," he says. "But we'll also
have to be careful that we don't
head back into a dark age of
medicine where we don't offer
that care to anyone."
Even with federal aid, training
residents drives up costs at hospitals. In an increasingly competitive market, hospitals may
.
.
become unwilling to continue
foot1ng the bill. In other countries, graduate medical education can
be funded through a tax on health care, but America's political
cl1mate makes that approach unlikely here. ''I'm not sure who 1s going
to end up pay1ng for it," Logue admits.
. Logue sees future research funding coming more from the
pnvate sector and less from public sources. He also says that there's
~goo~ chance ther~.will be fewer students going into pure research.
They re not dumb, he po1nts out. 'They look and they see that in
the future, there's not going to be as much money."
The "baby boom" demographic increase in the number of the
elderly, plus rising costs and continuing fragmentation and mobility
~f fam11ies, ~ill cause a crisis in care for the elderly, Logue predicts.
Everybody s go1ng to want to go into nursing homes and no body's
going to want to pay for it," he states. "This is not really a medical
problem, but s1nce 1t gets paid for out of the same pot, it will end up
be1ng a problem for medicine."
_ J.A .

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DAVID G. ELLIS, M.D., ASSOCIATE DIRECTOR of the emergency department at Erie County Medical Center, is at the vanguard of sharing
med1cal data, expertise, and protocols using personal computers and
videoconferencing-an emerging technology called medical
informatics, ortelemedicine. "Every specialty is going
to look at this and apply it," he predicts. Computer- ( DAVID G. ELLIS, M.D., ON MEDICAL INFORMATION TECHNOLOGY )
ized protocols and video link-ups are the future as
surely as managed care is, he believes; in fact,
telemedicine will be inextri-

Com put e r s w iII

cably linked with managed
care in the name of efficiency.
The goal of informatics is to organize information so it can be shared by doctors and
other medical staff in numerous, widely separated locations. The system will enable professionals to share information about specific patients, as well as
protocols concerning entire classes of patients. Ellis hopes it will
make treatment as efficient and uniform as possible in a manner
cons1stent with the latest literature and practice, and in keeping w1th
the goals of managed care. "The goal of the new medicine IS to keep
people 1n the best health at the lowest cost, preferably at home," he
says.
Videoconferencing helps doctors and hospitals make scarce
expertise and resources available over a larger geographic area. With
a v1deo camera wired to a personal computer, doctors can examine
a pat1ent and consult with each other even if they are miles apart.
As an example of the possibilities, a new distance education
room 1n the Health Sciences Library at UB's medical school allows
nurse-practitioner students in the town of Olean to attend class in
Buffalo without physically making the trip. Ellis is also pioneering the
use oftelemedicine at the Erie County Holding Center and the Attica
Conrectional Facility. T elemedicine makes its possible for doctors at
ECMC to examine prisoners at Attica and consult with nurses at the
prison without any of the financial, security, or time concerns that
anse when prisoners are transported. The telemedical examination
at the prison takes a few minutes, while the round trip from the
hosp1tal would take several hours. And because the patient isn't
taken out of the prison, there's no security risk. Even the prisoners
like the new arrangement. Ellis has found that prisoners would rather
get qu1ck emergency care in the prison than be taken to a public
hosp1tal in shackles.
Ellis's vision of the future includes doctors connecting to a
medical Internet through their personal computers, or joining doctors from the community on virtual grand rounds without leaving
thew respective hospitals. T elemedicine will keep doctors cunrent,
curb feelings of isolation, and aid in the development of consistent
clinical pathways and protocols, he believes. In his own field of
emergency medicine, Ellis dreams of ultimately eliminating the
Waiting room altogether, instead collecting registration and medical
information through portable computers at the patients' bedsides
While they are being treated.
Ellis stresses that while technology will help establish consistency
in practice, it willnever eliminatetne art of medicine. Medicine will
always require flexibility because patients, diseases, and computers
are not completely predictable. However, protocols can shorten

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medical communication

length of stay, reduce costs, and improve survival rates. Doctors
should considertelemedicine a tool "just like a stethoscope," he says.
"This technology is no longer a big deal. The real challenge now
is relationships. This presents new ways for people to deal with each
other." Technology will not replace primary care physrcians, either,
he notes. It will merely enhance their capabilities. Consequently, Ellis
is not worried that medical students win resist informatics. As an
assistant professor at UB, he has found this generation of students
computer-literate and cognizant of the value of technology. "Even
doctors trained before the advent of personal computers are
learning more about computers and reaping the rewards of more
efficient practices," he says.
- BY ERIN ST. jOHN KE L LY
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Medical imaging will bring

to medicine

ALAN H. LOCKWOOD, M . D . , ON MEDICAL IMAGING

NEW WAYS OF iNTEGRATING INFORMATION will make medica\ imaging
nd new technologies will make 1t cheaper and more
morepowe rfiul . a
.
'bl
d'cts Alan H Lockwood M.D., director of Pos1tron
access1 e, pre I
·
'
Emission Tomography (PET) Operations for UB and the Buffalo VA
medical center.
.
.
.
PET , one of the newest imaging technologies,. will be Invaluable
.h
in studying diseases and abnormalities-espeoally ones w1t out
·
tom·1cal manifestations-because 1t measures chang1ng
0 bV\OUS ana
.
·
1
·
1 processes such as blood flow and glucose metabolism.
phys1o og1ca
·
f .
ood explains in some cases o Intractable
For exampIe, Lockw
.'
.
·1
magnetic resonance 1magmg (MRI) and computed
ep1epsy,
· · B 'd
·fy·
reveal no anatomical abnormalitieS. y 1 ent1 1ng
tomograp hY(CT)
underactive regions of the brain, however, PET scans can find the
locus without the hazards of more invasive methods.
PET will also lead to steady progress 1n leam1ng about normal,
· 1 av he believes Because 1t can measure blood flow
I hy phys1o
heat
obt'
·

to various sections of the brain, PET is an ideal tool for finding out
how the brain performs everyday yet still mysterious tasks, such as
thinking and talking. Lockwood and his colleagues have already
begun PET studies of people as they process language. "We'll begin
to see the neuroanatomy of language production," he predicts.
"One of the future developments in PET technolo'6f is going to
be the fusion of physiological information with other sources of
data," Lockwood says. Computer programs to integrate and superimpose PET scan information with MR\s already help doctors locate
the site of a physiological abnormality with precision, he says. Further
progress will be made by combining PET, which records events
lasting about one minute, with electrophysiological methods that
work on a fraction of that time scale. The combination will show how
various brain regions work together to perform tasks such as talking
and reading.
Lockwood says it's unlikely that PET imaging itself will change
much. ''I'd say we're pretty close to optimal in that technolo'6f."
Instead, he believes, the invention of new radiopharmaceuticals will
expand how PET is used and make PET technology more widely
available.
New tracers to study the brain, the heart, and the origin and
spread of cancer are on the horizon. Lockwood also says less
expensive tracers will be developed that will be widely distributed
and used in existing primary care facilities. For example, a new
generation of tracers can be used in Single Proton Emission
Computed Tomography (SPECT) machines. These machines are
often available in community hospitals and outpatient facilities that
cannot afford PET systems.
Regulatory barriers will also fall as a consequence of the work
done in PET centers like the one in Buffalo, Lockwood predicts.
Currently, the U.S. Food and Drug Administration classifies PET
radiopharmaceuticals as experimental because their short half-life
makes it impossible to subject them to the kinds of testing required
for most drugs.
Although PET studies are expensive, they are far less costly and
hazardous than other alternatives such as exploratory surgery. That
means PET can be used to help physicians decide on treatment options.
Buffalo is the home of a unique committee made up of physioans.
hospital administrators, and insurance companies that is establishing
guidelines for the use of PET in the clinical setting. According to
Lockwood, this makes Buffalo a leader in facing the challenge of
determining how to use PET and other imaging technologies in ways
that are sound both medically and economically.
- J·A ·

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( JAMES P. NOLAN, M.D ., ON RESIDENCY EDUCATION )

Residency training will

create more

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RESIDENCY MIGHT CHANGE SUBSTANTIALLY in the future, with most residents heading for a generalist education and a small number choosing super-specialties, according to
James P. Nolan, M.D., immediate
past chairman of the Department
of Medicine.
Residency training will need to
reflect the medical community's
increasing emphasis on primary
care, says Nolan. Primary care skills
will need to be taught from the
first year of medical school, and
residency training will need to develop into more of a continuation
of medical training. It could even
be that most young doctors will go
through one generalist residency,
instead of selecting specialties.
T rain1ng will be very different for
the m1nority who choose specialties, Nolan believes.
"Those who do choose to enter the more technical aspects of
med1cine probably will see their education differentiate in the third
year of medical school, and they will go on to a highly specialized
residency after that. he says. Specialist residencies will become much
more focused and narrow, he believes. For example, radiologists
could become wedded to one imaging technology.
"We also will see changes in managed care and the way we've
originated that system," says Nolan, who expects to see a universal
health-care system like Great Britain's. Inpatient care will decrease
as hospitals focus on the sickest patients. Most health care, Nolan
predicts, will take place in ambulatory settings.
And while there still will be a need for critical care doctors, Nolan
said, residency training in the future will become more heavily
oriented toward preventive care and wellness.
"I think we also will see norms of treatment become similar for
all physicians, and variations from treatment guidelines will have to
be justified," he says. These care guidelines will be implemented to

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achieve efficiency, cost-effectiveness, and universality of care. The
downside, he wams, is that physicians may have less discretion in
terms of treatment.
The roles of different types
of health-care professionals will
be undergoing a change, Nolan
believes. "I think we will see a
blurring of the roles of physicians,
nurses, pharmacists and other
health-care providers. I think we
will see more working as a team,
and blending certain aspects. For
example, prevention and
counseling will be emphasized
across the board for all practitioners," he says.
UB already is working to meet
the needs Nolan sees developing.
''Moregeneralistskillswill be taught
to students earlier, and that's what
we're doing now," he notes.
But medical educators will need to do even more to facilitate the
changes he sees on the horizon. Medical schools, Nolan says, need
to develop more ambulatory sites and clinics throughout the
community that are staffed by university and clinical faculty.
"We have not been able to use physicians' offices as much as
we'd like. We still find that most tra1ning is in the inpatient setting.
We've got to find the resources to move out into the community."
Residency will likely become more a period of education and less
a term of work. "The service component is decreasing now.
Residents are not providing the same amount of service that they
once were required to. The education of residents is being stressed
much more than it has been in the past." That may lead to a change
in the way residency training is funded. Residents are now generally
on hospital payrolls, so their training is paid for by patients and thirdparty payers. If residency becomes more education-oriented, that
cost may be picked up by the government, Nolan explains.
- BY CHRISTINE VIDAL

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the family doctor, a narrowing of the salary gap between specialists
and generalists, and a smaller role for the hospital as more routine
care is performed in ambulatory or home settings.
Although she believes that managed care can bring new efficiency,
she does not think it will miraculously erase the high cost of care.
"Medicine is always going to be labor-intensive, and it's always going to
take a long time to train doctors and other professionals,'' she explains.
"And it's always going to take time for patients to respond to treatment

( SUSAN G. REGAN ON HEALTH CARE FINANCING )

Competition,
not regulation, will

and get better. No matter how much you pay the cellist, it takes
the same amount of time to play the string quartet.
"We will have to develop a better sense of distributive
justice," Regan says, pointing to the current lack of service to
the poor and to people
in rural areas. "It's a
form of rationing, but
it's not based on any
legitimate reasoning~
it's either how much
you can pay, or

the cost of health care
THE COMING REVOLUTION IN AMERICAN health care will create a system
that is vastly more efficient and, ideally, more fair than today's, says
Susan G . Regan , a member of the New York State Public Health
· ·
E ·
Council.
Regan, who is also a member of UB's Center for Clin1cal th1cs
and Humanities in Health Care, is an attorney who regularly lectures
at the medical school. She heads the health law department at her
firm of Magavern, Magavern &amp; Grimm, which serves as counsel to a
number of hospitals and health care prov1ders.
.
R
Pred icts that the country will reshape 1ts health-care
egan
k
"I h
system through market forces, not government ta eover. n t e
next 1 0 to 1 S years, we'll have a strong, deliberate movement
toward competition in health care," she says, po1nt1ng out that a New
York State government task force recently recommended that
·t 1 begin to negotiate reimbursement rates w1th all payers.
h
osp1 as
· ·
b
11
Under this plan, not only health maintenance organ1zat1ons, ut a
third-party payers~including Medicaid~would negot1ate payment
rather than follow rates set by the state. These are the k1nds of
measures that will likely begin to bring costs down, Regan bel1eves.
"This will undoubtedly cause some problems, but overall 1t will
lead us to greater efficiency. The days of the planned economy in
health care are gone," Regan says.
She does believe, however, that the nation'straditions of consumer
protection will probably lead to some government supervision ofthe
emerging system. "We may well dec1de that we need regulation a~
a balancing force, just as we discovered the need for ant1trust laws,
she notes.
"In the future, we will also reexamine how our tax policy
contributes to our problems," she predicts. For example, current law
subsidizes employer-provided health care by allowing employers to
deduct the insurance they provide their workers; yet it does not
force all employers to provide health insurance. The result is that
people who get no insurance from their jobs indirectly subsidize
those who do~the government collects the full amount of taxes
from the uninsured, and uses that money, in part, to give a tax break
to companies that provide health insurance for their workers.
Regan agrees with the many observers who forecast a return to

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whether in your town there happens to be an orthopedic surgeon."
At the other end of the scale, she observes, a few people at the end
of life receive far more care than they want or can benefit from.
Concerns about cost and about good medical care will necessitate
a more rational system of distributing care to those who need it.
There is a serious risk that managers may try to save money by
cutting back on needed services, or that doctors will be overly
constrained by cost considerations. We have not yet found ways of
avoiding those dangers, according to Regan, but it is essential to do so
ifhealth-care reform is to succeed and make Americans better off "Our
country is unique in that we have enormously creative thinking in the
insurance industry and among health-care providers, so I can't help but
think we'll come out of it with a better system," she states.
~J.A.

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( THOMAS ROSENTHAL, M. D ., ON FAMILY MEDICINE )

M.D .. CHAIR oF
UB's Department of Family MediCine, believes that the future of primary care is the future of medicine.
"Primary care is going to reemerge as the base around which
we build our health-care system,
the same as it is now in every
developed country with national
health insurance," he states. "Family
doctors have been managing the
care of the family for centuries."
Rosenthal himself practiced for
eight years as a family physician in
the farming community of Perry,
NY. He became medical director
of Buffalo General Hospital's Department of Family Medicine in
1986. He helped establish UB's
DIVISIOn of Rural Health in Cuba,
NY, and its residency program in
rural health. Rosenthal was also
the founding director of UB's Primary Care Resource Center.
Managed care and the need to control costs are strong incentives
to return to the model of the family doctor, Rosenthal explains. He
expects to see health care move toward some sort of national
insurance system within five years.
As primary care becomes more important, Rosenthal says,
schools will have to produce more generalists. "Medical schools will
have to focus on producing 50 percent oftheir graduates who go into
primary care careers. We will have to model primary care as the
exc1t1ng career it can be."
Rosenthal also predicts a move toward decentralization. "More
medical education will have to occur in the communities, and less in
hospitals,'' he says. Decentralization will make care more accessible. People
will be able to see doctors in nearby clinics, or have phone consultations,
or even receive home visits. The result will be earlier detection of disease,
and better prevention and management of chronic illness.
Hospitals will care foronlythe sickest patients. "If we improve the
access to quality primary care, we'll see fewer admissions because
THOMAS RosENTHAL,

they will have their illnesses better managed in an outpatient
setting. This has already been
proven." Hospitals will therefore
specialize in caring for advanced
and complex disease processes,
and incurable, terminal illnesses.
Doctors will have to receive better training in pain management
and end-of-life decisions, he says.
"These are issues thatfamily practice residencies have always
stressed,'' he adds.
"We'll need at least as many
hospital beds as there are today
because the population will be
larger, but we will need fewer
beds per thousand people,'' he
predicts. "However, the cost per
day will probably go up."
It is possible, Rosenthal says,
to provide better and cheaper
care without cutting back on the
amount of care. "Managed care
gets around rationing health care because you make wise decisions and
treat people appropriately,'' he explains. "You make a decision based on
a history and knowledge of a patient and their values, saving the lives of
people with the potential to return to a reasonable state of well ness
rather than prolonging the lives of people for more suffering."
Technology presents its own set of problems, Rosenthal
observes. Medical practitioners will have to decide whether
technological advances are saving lives or merely prolonging
suffering. "That's a real tricky, difficult question that we've put off
answering." For example, imaging and advanced tests have made
it possible to detect prostate cancer earlier than ever, but there's
still no consensus on what to do with that knowledge. Surgery
and other aggressive treatments may save some lives, but
sometimes the treatment causes unwelcome side effects and
does not prolong life. A second stage of research is needed to
determine how best to treat prostate cancer, says Rosenthal.
-BY

CHRISTINE

VIDAL

The future
. . of medicine
IS In

care
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JEROME J. SCHENTAG , PHARM . D ., ON PHARMACEUTICS

DISEASE ORGANISMS ARE BECOMING RESISTANT to drugs faster than drugs
are being developed. In the next five to _1 0 years, doctors will see
increasing numbers of patients dying from 1nfect1ous diseases such as
pneumonia.
But pharmaceutics professor Jerome j. Schentag, Pharm. D.,
he
d oes n't believe this crisis spells the end of med1c1ne. .Instead,
.
believes that doctors will find better ways of using ex1stmg drugs,
d that research will focus on boosting the immune system to
an
.
. ..
take over the fight against disease. "It's not a hopeless SJtuatJon,

bugs were laying their strategy. They came back in force."
Although the imminent crisis has spurred new research, experience shows that it takes an average of seven years for new drugs
to progress from the test tube to the patient. 'There isn't anything
in the pipeline now that looks like a miracle drug. We are getting new
drugs, but they're mostly knock-offs of things we already have,"
Schentag says.
Two classes of powerful broad-spectrum drugs developed in the
1980s together make up 50 percent of the antibiotics sold today.
The third-generation cephalosporins attack bacteria by inhibiting
key reactions in the cell walls, while the advanced fluoroquinolones
interfere directly with bacterial DNA. "What we need, frankly, is
another one of those advances," Schentag says.

he says.
. .
"Five years ago, it looked like we were w1nn1ng. The bugs were
on the run," says Schentag, who is also the director of Millard
Fillmore's clinical pharmacokinetics lab. "The pharmaceutical industry pulled back a little, started investing in other areas. Meanwhile, the

Hospitals are beginning to address the problem by finding better
ways to use the antibiotics they have. Most hospitals save money by
buying drugs in bulk and then using up their supply, but according to
Schentag, using the same antibiotic over and over in the same setting
helps breed resistant strains even more quickly. Instead, Millard
Fillmore and other hospitals are beginning to rotate antibiotics every
few months.
They are also paying closer attention to dosing by testing patient
cultures for resistance and boosting dosages in some cases to kill
slightly resistant strains before they have a chance to develop higher
resistance.
In the long term, medical research will concentrate more on
active and passive immunity, Schentag believes. That may include
attempts to create immunoglobulins that are specific to certain
diseases instead of the general ones in use now, as well as bacterial
vaccines like the one against Hoemophilus in~uenzoe that helps
prevent pneumonia and meningitis.
In the short term, however, only changes in drug use can slow
the development of drug-resistant bacteria. A simple thing like
instant diagnostic tests could allow doctors to determine bacterial
strains and prescribe very narrow-range drugs. More important,
according to Schentag, is getting doctors to be more restrained in
their use of drugs.
"If we ever get to the point where we stop giving antibiotics to
everybody with a cold, it would be the most revolutionary thing of
all," he says.
- J. A .

The diseases are

the drugs
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New ethical
are on the horizon
TouGH CHOICES IN MEDICINE will always involve ethical questions, but
better communication between doctors and patients could someday resolve many of the day-to-day problems that require the
intervention of ethicists like Stephen W ear, Ph.D.
"I hope people who do what I do at the bedside won't be
needed," says Wear, the co-director of UB's Center for Clinical
Eth1cs and Humanities in Health Care.
The author ofthe 199 3 book Informed Consent Patient Autonomy
and Physician Beneficence in Clinical Med1one, Wear holds joint
appointments in the departments of Medicine, Gynecology and
Obstetrics, and Philosophy. He heads the ethics consultation team
at the Buffalo VA medical center, where he is on call 24 hours a day,
seven days a week. He is also a member of ethics committees at
Hosp1ce Buffalo, Buffalo Mercy, Millard Fillmore, Children's Hospital,
and the Erie County Medical Center.
Wear is most often called to a hospital to resolve disputes
between families, patients, and doctors on issues of clinical ethics
such as informed consent. end-of-life decisions, and aggressiveness
of treatment. Frequently, he says. the debates are caused by
misunderstandings between doctors and families. He often clears up
problems by simply helping physicians explain diseases and treatments, and by translat1ng "doctorese."
Many of the issues around end-of-life decisions have already been
charted out conceptually, says Wear, whose
doctorate is in philosophy. What will hapSTEPHEN WEAR , PH . D . , ON MEDICAL ET HICS )
pen 1n the future, he predicts, is that doctors
will do a better job of putting the theories
there will be little need for bedside dispute resolution, Wear
into practice by clearly informing patients about their disease, prognopredicts. However, new ethical questions are always cropping up.
SIS, and choices. ·'One ofthe reasons people like me are around is that
"We'll be going through a very ugly phase as issues of health care
the profession has resisted internalizing these issues.
financing
are worked out," Wear believes. "We have to have this
"A great deal of conceptual progress has been made in biomedicrisis
because
we have only so many resources to go around."
cal eth1cs in the last 20 years," explains Wear. For example, at one
Concern for cost may force insurers to limit treatment. Health
point. refusing aggressive treatment was considered a suicidal act.
maintenance organizations may prohibit doctors from prescribing
Now, the concepts of informed consent and the right to refuse
expensive dnugs or discussing effective treatments outside the
treatment are widely accepted and have changed the terms of the
network. ''I'm very nervous about that. My guess is, society w ill make
debate.
some
poor choices along the way. I am hopeful that the right choices
Wear says that institutions will probably be pressured to change
will
have
been made in 50 years."
as well. Hospitals now concentrate on trying to cure diseases, rather
The
emerging
technologies of gene mapping and manipulation
than on managing death. Each death is discussed in detail in hospitals'
will raise new issues. The Human Genome Project, when completed,
morbidity and mortality meetings. "Deaths have to be defended,
could provide information about an individual's risk of illnessbecause there's always a suspicion that somebody m1ssed the boat.
information that. in t he best case could be used to prevent disease,
But 1n many cases, death is the only realistic outcome of a disease.
or in the worst case to cut off insurance. Parents may get the power
Why not focus the discussion on how the patient was treated,
to select the qualities of their offspring. "It's a way of making choices
whether pain was alleviated? Hospice has a lot to teach us," he says.
regarding another individual," Wear cautions, "and whenever you
As doctors and patients become better informed about ethical
do
that. you raise ethical questions."
- J.A .
questions of health care-and communicate better about them-

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FROM

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3

nance in resident and fellowship training.
• The merger of the University at Buffalo with the SUNY
system in 1962, of course, was the most significant event of
these 150 years. The merger was traumatic but important,
bringing an infusion of resources to make UB a
major public institution.
The period between 1962 and 1975 was
characterized by confusion, instability, diminished institutional self-esteem, disillusionment, an uncertain direction, and little
cohesion. The UB faculty had spent much
effort in defining its dreams for a medical
center comparable to those at Rochester,
Stonybrook, and Syracuse, but found that
those dreams were not shared in Albany.
When the bubble burst, poor morale pervaded
the school. This was reflected in critical accreditation reports in 1962, 1966, and 1972, a decline in
academic productivity, and deterios v J OHN NA
ration of the physical facilities.
The situation improved in 1973 with the recruitment ofUB's
first full-time vice president for health sciences, Dr. Fitzhugh
Carter Pannill. I was recruited as UB's first full-time dean in
1975, and am forever grateful to Carter and to UB's president at
that time, Dr. Robert Ketter, for offering me this exciting
opportunity.
Certain facts were apparent when I came:
•UB and the community possessed a wealth of resources
which included capable personnel, diverse hospitals, and a
large population base. Those could provide the cohesiveness,
ethos, and energy to develop a mature medical school.
•Many of UB's best faculty had not received the national
recognition they deserved. Now that UB's ability to compete
with the best is established, this should never occur again.
• Continued achievement of excellence required the acceptance that UB and the community were interdependent, and
that meaningful programs were more likely to flourish through
cooperation than competition.
UB's medical school of 1996 is far different from thatof 1946.
It has experienced five successful accreditation visits between
1976 and 1995. It has developed a core academic center with a
world-class Health Science Library, magnificent educational
facilities , a modem vivarium and biomedical research complex,
and the schools of dental medicine, nursing and allied health
professions. UB and its affiliated hospitals have defined both
their individual missions and their shared ones. A strong
volunteer faculty supplements UB's academic faculty. Most
importantly, the medical school attracts academically competitive students, residents, and biomedical graduate students.
Enough of the past and present. What of the next 150 years?
In my opinion, the faculty, the university leadership, and the
hospital and community leadership have positioned UB well for
the future. For UB and all institutions of higher education, the
new economy and social order will encourage sharing,
collaboration, and interdisciplinary activity. There will be

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increased emphasis on independent learning, increased use
of technology, less classroom experience, and more attention to outcomes rather than to process and regimentation.
Such change is already occurring at UB . Continued
transformation will take another generation. But by building
on past achievements and today's optimism, UB's
medical school and its community partners will
provide the best in education, health care
and leadership.
These assets will help us meet the
challenges ahead:
• The medical school has a core of educational and research facilities to sustain
its mission well into the next century.
• The new fiber optic network linking
the campus and hospitals with other places
in the state provides the infrastructure for
distance learning, transmission of library information, and the continued development of the
region's health system informaUGHTON ,
M . D .
tion superhighway.
• UB's biomedical research program generates more than
$30 million annually. Together with a faculty practice plan
that generates almost $80 million dollars a year and the
complementary resources provided by New York State and
the hospitals , the school will be able to educate physicians for
the future.
Two projects are planned in the next five years to help the
school meet its obligations to its students andiacult.y:
•The Comprehensive Health Education Center will be
built in the old dental school building at the north end of
Farber Hall. It is envisioned as an interdisciplinary center for
community health education research, problem-based education, and the teaching of interview skills and physical
diagnosis. The center will provide a modicum of patient care
shared by the various health science faculties , and, we hope,
a centralized autopsy facility coordinated among the teaching hospitals.
•The second and third floors of historic Harriman Hall
will become the locus of the medical school's administrative
offices while its first floor continues to provide student
support services. The building is connected to the Biomedical Research Building at the second floor level, uniting the
South Campus health sciences core.
As we celebrate UB's Sesquicentennial, there are many
reasons for optimism. Future research, education and patient care will be interdisciplinary. Biomedical research will
become more cooperative and collaborative. Education will
be interdisciplinary, combined with more independent learning. Patient care will become more integrated and comprehensive.
My dream for the year 2146 is that UB's leaders of the past,
present, and future will meet in the great unknown to
evaluate how each generation has remained faithful to the
dreams of Millard Fillmore and UB's founders .
Happy 150th B ir t h da y UB !
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UNIVERSITY AT BUFFALO SCHOOL OF MEDICINE AND BIOMEDICAL SCIENCES has a long and distinguished
history-and you ore port of it_
In celebration of its Sesquicentennial, a beautifully illustrated pictorial history of the Medical School
is available for your personal library or office_
This hardcover, 192-poge keepsake, Another Ero, contains 250 photos, including rare, historical
photographs that will transport you to a time when___

Medical School tuition was $65 a year and "good board,
with room, fuel and lights" could be found for $4_50 a week_
UB medical students were the first in the United States to witness a clinical demonstration
of a live birth-which caused an outcry in newspapers nationwide!
Retrace 150 years of achievement, trials and tribulations in this special limited volume, and toke pride
in the Medical School's vision for its future_

To order Another Era by credit card call Wadsworth Publishing Company at 1-800-369-2646 exL 3339
$39_95 including shipping and handling. Gift cards available upon request. Charges will appear on your statement as Wadsworth Publishing.

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ARTHURT . SKARIN ' 61

, ofNeedham,MA,

E . GORMAN ' 36, of Hilton Head, SC,

published the second edition of his Atlas of

has been active at the Volunteers in Medicine

Clinical Onco logy. Skarin is the chief of the

Clinic on Hilton Head Island since 1993. The

hematology laboratory and the medical di-

FRED

organization provides free medical service to

rector of the thoracic oncology program at

6,000 to 8,000 people who have no other

Dana-Farber Cancer Institute, and teaches at

medical care.

Harvard Medical School. The book is the first

The State University of
New York at Buffalo Department of Family Medicine is
continuing to grow and expand. We are seeking BE/BC
Family Practitioners to join
us in varied urban and suburban settings throughout
Buffalo and Western New
York. The candidates we
seek must have interest in OBI
GYN and assume teaching
responsibility for medical
students and residents. Benefits include competitive
salary, ample vacation,
sick time, CME time, and
licensure/board fees. If any
of these opportunities sound
of interest, your colleagues
here at Family Medicine
would welcome the chance
to speak to you.

of its kind to cover all aspects of oncologic

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ALEXANDER GRINSTEIN '42 ,

tumors and malignancies. About half the

5

photos in the atlas come from Skarin's teach-

of Beverly

ing collection, gathered as part of his hobby

Hills, MI, announces his most recent publi-

of photography. Skarin's post-UB career be-

cation, The Remarkable Beatrix Potter. His

gan with a fellowship at Boston City Hospi-

previous publications include Freud's Dreams,

tal. Near the end of the Vietnam War, Skarin

Freud at Crossroads, Conrad Ferdinand Meyer

was drafted and spent two years in the U.S.

and Freud, and Freud's Rules of Dream Inter-

Air Force. After returning to Boston, he helped

pretation. Alexander is president of the

Dr. Sidney Farber develop a medical oncology

Sigmund Freud archives.

9

program at the Children's Cancer Research

0

5

Foundation, which later became the Dana-

5

Farber Cancer Institute. Skarin says he some-

of Dallas, TX,

times reminisces about Buffalo with friend

while chairman of psychiatry at the Univer-

who is a daughter of longtime UB professor

sity of Texas Southwestern Medical Center at

Oliver P. Jones, Ph.D., M.D.

KENNETH ALTSHULER ' 52 ,

Dallas, was named 1995 Professional of the
E.

of Delhi, NY, was

Year by the Dallas Alliance for the Mentally

JOHN

Ill. The group honored Altshuler for helping

selected a fellow of the American College of

establish Mental Health Connections, a co-

Physicians. He recently completed health-

operative program ofUT Southwestern's De-

care management training at the Kenan

partment ofPsychiatry and the Dallas Mental

Flagler School of Business, University of

Health and Mental Retardation Center.

North Carolina at Chapel Hill.

SHIELDS '68,

Altshuler, who holds the Stanton Sharp Dis-

9

tinguished Chair in Psychiatry at UT Southwestern, recently assumed the presidency of

7

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JAMES J . MCCOY JR . '71 ,

5

of Charleston,

sc, is medical director of the Charleston

the American BoardofPsychiatristsand Neurologists.

Please contact Rebecca
Brierley, Professional Affairs,
Department of Family
Medicine, 462 Grider Street,
Buffalo, NY 14215 (716)
898-4797; Fax (716) 8984750. EOE/AA

Surgery Center and a member of the
Arthroscopy Association of North America,

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5

and was recently installed as president of the

of Waltham, MA, was

South Carolina Orthopedic Association. He

elected to the executive committee of the

has seven children and soon will be a grandfather.

HARRIS FAIGEL ' 60 ,

section on Ado lescent Health of the American Academy of Pediatrics and was appointed

STEVE TUCKER '72 ,

chair of the finance committee of the Society

of Anchorage, AK, is

in solo practice in nephrology. He is gover-

for Adolescent Medicine. His third grandchild (first grandson) arrived last June. His

nor-elect of the ACP in Alaska and serves as

wife, Frayda, is enrolled in the psychiatric

director of the Alaska/Northern Alaska Kid-

nursing track for a M.S.N. at Northeastern

ney Center and chairman of the pharmacy

University.

and therapeutics committee. He has two

We encourage the inquiries of women and minorities.

adopted children, Jacob Ian, 5, who skates,

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Ifyou thought

'

you knew us...
do J.OU know
what's NE.W?

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skis, and plays soccer and hockey;

jackie (5 1/2), Alex ( 4), and Eric

and Alanna Elizabeth, 15 months.

(19 months).

JAMES P .

o""e'(
\

of

BU R DICK '75,

is the director of anesthesia ser-

for an essay about lesbian battering entitled Strike One. Apractic-

ban Hospital in Buffalo and a

ing psychiatrist, she ha also pub-

member of the board of directors
and president-elect for the medi-

lished features , es ays, fiction,
and poetry in the U.S., Canada,

cal staff of Millard Fillmore

the United Kingdom, and Aus-

Health System. He also serves on

tralia. Her first book, a collection

the board of the

ew York State

of interviews with female musi-

Department of Health's Office of

cians-including Marianne

Professional Medical Conduct.

Faithfull, joan Osborne, Laurie
Lewis, and Grammy-winnerjanis

of

ment. He was also promoted to
lieutenant colonel in the medical

Ian-will be published this year.
Post lives with her long-term
partner, judith Avery, a psychiatric nurse.

corps of the U.S. Air Force Re-

9

serves at Langley Air Force Base,
where he serves as a gynecologist
in the Women's Health Center.

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M ICHELLE SKRETNY SUSCO

'91 , of Clifton, VA, is a board-

certified pediatrician in a small

of

group practice in Manassas, VA.

Washington, D.C. , has spent the

She married joel Susco on Sept.
2, 1995.

T ER EN C E

CHORBA ,

'79 ,

past year helping improve disease surveillance systems in five

OBITUARIES

central Asian nations as a CDC
epidemiologist in Kazakhstan.

MARVIN

N . W I NER , '39, of

Sarasota, FL, died Dec. 27, 1995.

Rooms .1vailahlc for
UB Alumni Weekend
October 4-6, 1996

9

Congrarularions
to The University at Buffalo School
ofMedicine &amp; Biomedical Studies on
celebrating I 50years ofteaching,
healing and research!
FromnNf-~

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He was born in Buffalo, and after

MAR K 5. B O R E R '80, of Dover,

earni ng his M.D. , served three

DE, was rated a "Top Doc" in the

years in the U.S. Army Air Corps.

state by 200 medical colleagues
in the ovem ber 1995 issue of

He practiced dermatology in Buf-

Delaware Today. Mark is board-

an instructor at UB. A Fellow of

falo from 1946 to 1981 and was

certified in psychiatry and child

the American College of Physi-

psychiatry.

cians and of the American Medical Association, he was also a

MARC

BUFFALO~arrtoft

1340 Millersport Highway, Amherst, NY 14221
(716) 689-6900 or (800) 334-4040
At the Univers1ty at Buffalo Complex

0

STANLEY '78,

of the Richmond Health Depart-

• A first-class hotel with outstanding
amenities, comforts and conveniences - centrally located at the
University at Buffal o Complex.

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LA U RA POS T '87,

East Amherst, NY, is the president-elect of the ew York State
Society of Anesthesiologists. He

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See Why
,:~'~~ ~;:.O~
e,C.\.~ \~ '(
We're Your Ideal _,~~ s~~,,o&lt;:'&gt;
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. Fact·1·tty... \~ &lt;i&gt;'1~~s J.
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K O B LICK

'84, of

Ormond Beach, FL, became a

form er pre ident of the Central
tales Dermatologic Society. He

fellow of the American College

was a member of the Landings

of Surgeons. He and his wife,

Racquet Club. He moved to

Helene, have three children :

Sarasota 10 years ago. He is sur-

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••

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•••••••••••

•

• • •• • • •

HUR\VITZ &amp; FINE, P.C.

I

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ATTO R NEYS AT LAW

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THE ULTIMATE DRIVING MACHINE:

S ERVICING

THE L EGAL

vived by his wife, Helen M.; his daughters,
Beth Berenson of New York City, and Ellen

N EEDS OF THE

Litman of San Francisco; and four grandchildren. Memorial donations may be made
to University of S. Florida Allergy Research,
Account #25040, care of the Division of

H EALTH S CIENCES
COMMUNITY

Allergy and Immunology, University of S.
Florida College of Medicine, VA Hospital,
13000 Bruce B. Downs Blvd., Tampa, FL
33612.
PAUL ROBERT MOYCE,

• Managed Care
• Purchase &amp; Sale of Practices
• Business &amp; Tax Planning

'70, of Mountain

Checkpoint
Foreign Car, Inc.

View, CA, died peacefully Oct. 19, 1995 as
the result of a severe head injury. He was
surrounded by his loving family. Born in
Buffalo, he graduated from the University of
San Francisco in 1966. After earning his

• HCFA Safe Harbor Regulations
and Physician Self-Referrals

Sales and Service

• Contracts with Private

•

• Employee Relations

&amp; Public Entities

M.D., he served in the U.S. Air Force as a
flight surgeon. He was board-certified in
anesthesia in 1977 and began his practice at
Dominican Hospital in Santa Cruz. He vol-

Counseling

487 Kenmore Avenue
Buffalo, NY 14223
836-2033

unteered for the Santa Cruz Suicide Prevention program and Hospice. A growing interest in mental health led him to enter a
residency in psychiatry at the University of
California at Davis in Sacramento. He obtained his second board certification and
began a private practice in psychiatry in
Menlo Park, CA., in 1990. He enjoyed literature, travel, music, and the exploration of
the spirit. An accomplished pianist and vocalist, he sang bass with the Cabrillo College

• Fringe Benefit Programs
• Representation Before
Government Agencies on

•

Audit &amp; Business Issues
• Facility Finance

Your WNY Leasing Specialist
Serving WNY proudly
for 33 years

and Construction
• Credentialing
and By-Laws

Slavonic Chorus and toured the Soviet Union
with them in 1987. He is survived by his

• Hospital/Medical Staff Issues

wife, Kaki; his daughter, Audrey; and his
son, Gregory, of Seattle, WA. Donations

Please contact
Robert P. Fine or
Lawrence M. Ross
at 716-849-8900

may be made to the Audrey Saxon Moyce
Education Fund, care of David Moyce,
trustee, P.O. Box 1883, El Grenada, CA
94018.

We have more class notes than we could fit into
this special issue. They will appear in the
Summer 1996 issue.-The Editor

1300 Liberty Building
Buffalo, New York

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PLANTING

A TREE UNDER WHICH You WILL NEVER SIT

DR. DEVILLO W. HARRINGTON, class of 1871, knew how to make his money ' grow. In fact, this man who in 1905
provided $5,000 through his will for. the University at Buffalo School of Medicine,
is still supporting UB today through the endowment his bequest created.
THIS PERMANENT endowll)ent in Dr. Harrington's name has grown to over $300,000
and today it supports the famous Harrington Lecture Series, which twice a year brings
distinguished scientific speakers to the School of Medicine and Biomedical Sciences.
) Uf

he

DR. HARRINGTON'S LEGACY to UB is just one of many bequests which have established permanent and important
endowed funds at the school. They enable UB to prov1de scholarships to outstanding students,

.ve

At

enhance scientific research, support excellence in teaching and meet the ever-changing needs of the scho,ol.
YOU TOO can provide the School of Medicine with a measure of permanence through a bequest. Proper estate planning
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. plan. Acharitable bequest prov1des
. the. sat1sfact1on
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. a tree

ere
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FOR ACONFIDENTIAL consultation on making a bequest to the UB School of Medicine and Biomedical Sciences, or to
receive materials to share with your attorney or estate planning advisor, please contact:

r

STEPHEN

A~EBSARY, JR. ~
-

- - --

~

Assistant Dean and Director of Development,
School of Medicine and B1omedical Sciences

UNIVERSITY AT BUFFALO

(716) 829-2773

UNIVERSITY AT BUFFALO
SCHOOL OF MEDICINE

ISO

YEARS

•e•e · •••e
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BUFFALO PHYSICIAN
STATE UNIVERSITY OF NEW YORK AT"BUFFALO
3435 MAIN STREET
BUFFALO NEW YORK 14214

ADDRESS CORRECTION REQUESTED

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Non-Profit Org.
US Postage
PAID
Buffalo, NY
Permit No. 311

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                    <text>State University of New York at Buffalo School of Medicine and Biomedical Sciences, Summer 1996

oes me 1c1ne
deal with death?

�BUFFALO PHYSICIAN

\olume 30. Number 3
ASSOCIATE VICE
PRESIDENT FOR
UNIVERSITY SERVICES

Dr Carole '&gt;nuth Petro
ACTING DIRECTOR OF
PUBLICATIONS

Kathryn \ Sawner
EDITOR

Je&gt;SICa Ancker
ART DIRECTOR

\ian J Kegler
ASSISTANT DESIGNER

Julie Gmten
PRODUCTION MANAGER
\nn Raszm~1nn Brown
STATE UNIVERSITY OF
NEW YORK AT BUFFALO
SCHOOL OF MEDICINE
AND BIOMEDICAL
SCIENCES

Dr John Naughton, Dean ,

\ ·"c Ptcsidcrll fo• Cliniwl A{f&lt;111 s
EDITORIAL BOARD

Dr John A RIChert . Cluurmmt
Dr Martm Brecher
Dr llarold Brod)
Dr. Rtchard L. Collms
Dr. Jack f Co) ne
Dr. Alan J Dnnnan
Brian Dufh
Dr James Kanskt
Dr Barbara MaJerom
Dr Elizabeth Olmsted
Dr Charles Paganelli
Dr Stephen Spaulding
Dr BradiC\· T. Truax
Dr r rankltn Zcplowttz

Dear Alumni and Friends,
THE SESQviCENTE:-o'\IAL E\E'\TS during the first two weeks of May truly
rel1ected the commitment of the school's alumni, faculty, and friends
to its missions and accomplishments. A major highlight was the
opportunity to have Helen Ranney, M.D., deliver a stellar Harrington
Lecture, receive an honorary Doctor of Science degree, and give very
warm, well-directed remarks to the 1996 graduates. The commencement was also highlighted by the attendance of 29 members of the
class of 1946, gowned and hooded and sitting on the stage with other
faculty and distinguished guests.
Spring Clinical Day was a resounding success in its own right. It
drew probably the largest gathering of medical school alumni ever to attend this annual
event. The session focused on issues related to preparation for death, the theme of this
issue of Buffalo Physician. For me, it was amazing to experience the warmth and
humaneness exhibited by a UB alumnus, Robert Milch, M.D., the medical director of
Hospice Buffalo and an organizer of the session. He, with Ms. judith Skretny, set a tone
which served to galvanize the audience into a cohesive, concerned, attentive group which
ensured a successful learning experience for the entire day. The program was further
highlighted and enriched by a singularly gifted presentation by the Stockton Kimball
lecturer, Sherwin Nuland, M.D.
As I rel1ect on the school's focus on its 150-year history, it is indeed rewarding and a
pleasure to see a renewed awareness ofUB's successes and its willingness to commit itself
to another 150 years of dedication to educate outstanding physicians and biomedical
scientists.
Sincerely,

~~.
John Naughton, M.D.
Vice President for Clinical Affairs
Dean, School of Medicine and Biomedical Sciences

TEACHING HOSPITALS AND
LIAISONS

fhe Buffalo (,eneral llospttal
\ftdwd )lww
I he Chtldren·s Hospttal of Buffalo
[ne Count\· Medtcal Center
Mercy llospttal
'vltllard fillmore llealth System

Dear Distinguished Alumni,

fnmll.Sa\'a

Ntagara Falb Memonal Medtcal
Center
Ro"sell Park Cancer lnstilllte
St&gt;te" of Chanty lio&gt;pnal
DCillll\ \f&lt;Cmllt)
\eterans Aff.m&gt; Western '-Oew York
lleahhcare sy,tem
© The State L·rmnSit) of '\ess York
at Buffalo
Buff&lt;~lo Phnrcwn " publtshed
quarterly b\ the !&gt;late Lmve"nv of
Ness York at Buffalo School of
\.1cchunc and Biomcd1c.:al Science~
and the Offtle of Publtcallons It rs
sent , free of charge.toalumm , faculty ,
student; , re;tdents and fnends. fhe
staff r._enes the nghtto edn all cop)

and submi.,c,lons accepted for

puhltcallon.
4\ddrcss questions , comments and

&gt;ubmisstOns to: The [dnor, Buf{lllo
Ph)-\itian. '-,tate Uni\·cr'-tll\. of r\e\\

York at Buffalo . Office ·o r Publt callon; , 136 (rafts I tall , Buffalo,
'\1) 14260
Send address changes to: Buff&lt;~ln
Phl;t&lt;illn, 1-!6 CFS Addnton , H35
\lam Street , Buffalo, 1\Y 1-!2 H

(over Image: Scala/Art Re;ource. 1\Y
Fdsard \lunch , Thr Dc&lt;tth Chwnbcr ,
Munch Museum , Oc,lo, r\orway.

THA'\K YOL FOR the opportunity to serve as the president of the Medical
Alumni Board of Directors. Much gratitude is due to Margaret
Paroski, M.D., whose shoes I need to fill-a task that will be hard to
accomplish. She served with vision and commitment, and was an
example to our students of a caring, effective teacher and clinician.
Also, congratulations to Beth Maher, M.D., for an outstanding
Spring Clinical Day program, "The End of Life: The QualityofDeath."
The program attracted more than 300 physicians and was one of the
best attended Spring Clinical Days ever.
1
It is with great pleasure that we continue the celebration of the
sesquicentennial anniversary of our medical school with the Distinguished Medical
Alumni Award, to be presented this Septemberto Elliott C. Lasser, M.D., class of 1946. Dr.
Lasser's research in radiology has been the cornerstone of some of our present-day
diagnostic techniques. This recognition is a source of pride for all our alumni.
Plans for the 1997 Spring Clinical Day are already under way. Richard Collins, M.D. ,
is planning a program addressing the impact of managed care on the physician and the
patient. The Alumni Association will also continue to sponsor a wide range of activities for
medical students, including the community physician program, the senior reception,
orientation events, and receptions at national medical meetings.
As your new Alumni Association president, I look forward to this year, and I ask for
your support and any ideas to better serve you and our future physicians.
Sincerely,

~if C'~

/W:J

Jack F. Coyne, M.D.
President, Medical Alumni Association

�V OL UME

30 ,

3

NUMBER

SUMMER

Buffalo Hospice

5
A

TEAM THAT CARES FOR

DYING P ATIENTS TAKES

ON A

NEW ROLE: EDUCAT-

10

Physician-Assisted
Suicide
How FAR

SHOUL D

DOCTORS GO?

by Jessica Ancker

lNG YOUNG DOCTORS.

18

1996

The End of Life and
the Quality of Death
U S 'S S PRING CLINICAL

DAY OPENS

DISCUSSION

ON CARING FOR THE

by Andy Danzo

TERMINALLY ILL.

by Scott Thomas

Research

Medical School News

BUFFALO GENERAL

DISTINGUISHED

GETS KUDOS. ALIENS AND

ASTHMA . HELPER DOGS .

PROFESSORS .

ROBERT N.

SPENGLER . EUGENE

MINOELL. MATCH DAY .

GIFTS TO UB .

Alumni News

LYNNETTE

NIEMAN ' 7 8 OF THE

History of Medicine

NATIONAL INSTITUTES OF

NATIONAL MEETINGS HELD

HEALTH. THREE GENERA-

IN

TIONS AT UB .

BUFFALO .

AStudent's Perspective
" I HAD NEVER KNOWN SO
MUCH ABOUT ANYBODY. "

BY CHRIS SCHAEFFER,

CLASS OF 1 998 .

Classnotes

�! l··· ·· · ·· ······· · ········· · ·· · ··· · · ··· ······· · ··· ··· ········· · ·· ·················· · ········

Dogs can help people with
impaired mobility
ervice dogs promote independence
and high self-esteem among individuals with impaired mobility, and
they can also save money, according
to UB researcher Karen Allen, Ph.D.
The research by Allen and her
colleague,Jim Blascovich, Ph.D., found
specially trained dogs
more cost-effective and
useful at performing certain tasks for people with
severe mobility problems
than human helpers.
They reported their
findings in the April 3
issue of thejoumal of the
American Medical Association.

The ubjectsofthestudy
suffered from muscular
dystrophy, muscular sclerosis, spinal cord injury,
or traumatic brain injury, and had used
wheelchairs for mobility for at least two
years before the study.
The dogs were trained to pull wheelchairs, carry parcels, help with daily dressing, open and close doors, assist in getting in and out of cars, and pull people up
from lying or sitting positions. They were
even trained to pull their owner to safety
in an emergency. Some canines have
learned to assist with as many as 100
tasks, Allen said.
Twenty-four of the individuals were
given the trained animals one month
after the study began. The other 24
received their canine helpers 13
months later.
In both groups , the dogs' assistance
cut the amount of time required by
human helpers by approximately one
half within six months.
Also , the subjects' self-esteem scores
nearly doubled in six months, and tripled
by the end of the two-year study. The

0

individuals reported newfound independence, increased psychological well-being, and positive effects in other areas of
their lives.
At the end of the study, 40 out of the 48
subjects were able to get pan-time employment, and 18 of the subjects started school.
A service dog costs about 5,000 to
train and about $1 ,100 to maintain
annually, far less than the cost of home
health aides or other assistants , Allen
said. While seeing-eye
dogs are well-accepted
and covered by many insurers, other types of service dogs are often not
covered. However, the
state of Montana is providing Medicaid coverage on a trial basis as a
result of this study, Allen
said.
Allen , a member of the
psychology department,
is the former assistant
director of UB's Center
for Behavioral and Social Aspects of
Health.
+
H E R 5 C H

E

L E

M E L 5 0

N

Buffalo General honored by
national accreditation group
he Buffalo General Hospital has
been awarded a three-year accreditation with commendation by the
joint Commission on Accreditation of Health Care Organizations
for the first time in its history.
Accreditation with commendation
recognizes excellence and places Buffalo General in the top 12 percent of the
5,200 accredited hospitals in the country.
joint Commission members reached
their conclusion after spending about
three weeks last December conducting
surveys at Buffalo General, its Community

a

u

f

f

o

t

o

Mental Health Center, and its long-term
care facility at the Deaconess Center.
"Buffalo General is to be commended
for its commitment to providing quality
care to the people in its community and
region," said Dennis S. O'Leary, M.D. ,
president of the joint Commission.
"You have a lotto be proud of: superb
people, excellent staff really doing a
great job. It's clear they really care," said
joint Commission surveyor Robert
eher. "The quality of the programs
really stands out. "
+

Aliens and asthma
n innovative experiment involving a popular children's movie
may have pinned down the neurological pathway by which unpleasant emotions constrict airways in asthmatic children.
UB pediatric psychiatry researchers
Bruce Miller, M.D., and Beatrice Wood,
Ph.D. , reported their results at the annual meeting of the American Psychosomatic Society, March 7-10 , in
Williamsburg, VA.
The researchers invited 24 asthmatic
children ages 8 to 18 to watch the video
of "E.T.- The Extraterrestrial," while
their heart rates , respiration rates , and
blood oxygen saturation were monitored . Airway reactivity and pulmonary function were tested before and
after the movie by spiro metry and
methacholine challenge tests.
The researchers were particularly interested in the children's physiological
responses during a highly emotional
scene in which the young hero , Eliot,
talks to what appears to be the dead
body of his friend , E.T. -then discovers
that E.T. is alive. The mood shifts suddenly from hopelessness to relief and
joy.
Results showed that during the sad
scene, heart rate and oxygen saturation
became unstable, reflecting airway con-

Physician

Summer

t

9

9

6

�··· · ···· · ······· · ······· · ·· · ··· · ····· · ··· · · · ·········· · · · ······· · ········ · ··· ·· ···· · · · ···· •

.
striction. During the happy scene, heart
rate and blood oxygen stabilized , indicating open airways.
In addition , the researchers noted
that changes in activity of the vagus
nerve , known to influence both heart
rate and airway constriction, correlated
closely with changes in the children's
emotional responses . They believe the
finding points to the vagus nerve as one
pathway by which emotions affect
asthma symptoms.
"These findings are clinically important because they suggest that emotional
conditions, such as depression and hopelessness, may be important triggers of
airway constriction in asthmatic patients," Miller said. "Knowing that the
vagus nerve is a specific pathway for
inducing these psychophysiologic responses, we can now target this pathway
for treatment intervention. "
Miller suggested that antidepressant
medications with strong anticholinergic
properties may be the best choice for
treating depression in
asthmatic children.
"These medications
may have the dual effect of treating depression, while at the same
time lessening vagal
responsivity , which
would directly improve asthmatic symptoms, " he said. "We
need to point out to
physicians that treating the depression can
improve asthma symptoms , as well as mood. "
The "E.T ." study is
part of a long-term collaborative effort by
Miller, the director of
pediatric psychiatry at
Children 's Hospital
and a UB associate professor of psychiatry
and pediatrics , and

s

u

f

f

0

l

0

P

hys

i

Wood , the assistant director of the pediatric psychiatry department and a
UB assistant professor. The two came
to UB last year from the University of
Rochester.
An earlier study published by the
two colleagues in 1994 found that children who experienced more intense
physiological reactions and described
their emotional experiences in more
intense terms also experienced decreased pulmonary function and
heightened airway reactivity. Miller and
Wood believe that in this subgroup of
asthmatic children, strong emotions
activate a specific pathway in the autonomic nervous system that causes or
aggravates asthma.
In the long run, Miller and Wood hope
their work will help bring the study of the
body a little closer to the study of the mind.
"We believe that's where medical
education needs to go . It's stilted and
artificial to practice psychiatry in a
vacuum , or to practice medicine in a

cian

1

9

9

6

'.

vacuum ," Miller said.
Wood adds that health care professionals must also include a concern for
the patient's family and social setting.
"It's no good to treat the child individually. It's important to engage the family ,
and see how that impacts the child's
physiological functioning. " She hopes ,
too, to begin to develop a model for
health , not just for illness. "We need to
look more at the positive ways families
impact on physiology, not just the negative ways. "
Miller established his reputation in
the field with a benchmark 1987 study
on the links between depression and
fatalities from asthma. He conducted
in-depth interviews with families of
asthmatic children who had died from
their disease and with the families of
others who had survived near-death
experiences. He found that the children who had died were much more
likely to have experienced psychological stress and family turmoil , such as
a divorce or an impending separation . Also,
around the time of
their death , they were
much more likely to
have experienced feelings of despair and
wishes to die.
"My clinical practice
had suggested this link
long before, but this
was the best-designed
study to establish the
link ," says Miller, who
practiced family medicine for several years
before specializing in
psychiatry.
Wood joined Miller's
research after studying
the impact of family
stress on children with
Crohn's disease .
+
-LOIS

Summer

.. .

B

AKER

�nt

How does medicine deal with death?

DoES MEDICAL SCHOOL ADEQUATELY PREPARE DOCTORS to treat dying patients? Is it always possible

..
..

to control pain, or to facilitate a dignified death? What should the law say about a dying patient
who asks a doctor for a lethal dose of drugs?
These are some of the topics brought up for discussion at UB's Spring C lin ical Day, held May
I I on the topic of "The end of life: The quality of death."
This issue of Buffalo Physician further explores these questions in several re lated articles. The
first, "Hospice Buffalo," follows medical students and young doctors as they leam about
palliative care in UB's new hospice education program. "Physician-assisted suicide: How far
should doctors go?" explains recent developments in the legal and social debate about assisted
suicide, and tries to put them in ethical perspective.
Our Spring Clinical Day coverage includes excerpts from a panel discussion about dying
patients, their families, and their doctors, and a story about the Stockton Kimball Lecture
delivered by Sherwin Nuland, M.D., author of How

We Die.

In our new student column, third-year student Chris Schaeffer reflects on how death robbed
him forever of the chance to know one fascinating and mysterious patient.
We hope that this special issue will invite discussion and reflection on these difficult questions.

-The Ed ito r

0

B

uffalo

P

hysician

Summer

l

9

9

6

�•

ICe

by

Andrew

Danzo

Photos by K.C. Kratt

A team that cares for the dying takes on a new role:
educating young doctors
0 CAR PIEDAD, M.D., was still getting used to people calling him "doctor" when he visited some old
friends at Hospice Buffalo in late spring. At the nurse's station there were hugs for the young bear of a
physician, freshly graduated and preparing to leave for a residency down south. Here he was still Oscar.
Piedad looked at the Family Room, decorated with soothing pastels and simple, comfortable
furnishings . He recalled the Christmas party there. The family pets that came for visits. The meetings
with spouses and children

to

discuss final arrangements. He seemed

"IT OPE:\lED M\ EYES TO

Buffalo

Physician

A

to

miss it.

\\'HOLE NE\\ C0:'KEPT OF MEDICINE," he explained.

Summer

l

9

9

6

0

�HOSPICE

BUFFALO

lN THC 18 'v10 HIS
Physicians have a
since Hospice Buffalo
hard time saying
became a clinical
"enough," according
training site for the UB
to Thomas Raab,
School of Medicine
M.D., clinical assoand the Graduate
ciate professor of
Medical Dental EdumedicineatUB. "We
cation Consortium of
are trained to treat,
Buffalo, some 70 residiagnose, and evalu- ____dent and lJ) medical
ate; and if we don't
students have shared
know what's going
an exposure to palliaon, we treat, diagtive medicine that is
nose, and evaluate
still relatively unsome more," he said.
usual. They have
"We must compaslearned about pain management, symptom
sionately communicate to the dying patient
management, and working in interdiscipliand the family when medical technology
"You learn a
nary teams. They have comforted dying padoesn't have any more to offer them and it's
tients-some calm, some haunted by nighttime to stop. So many times, doctors don't
lot of loving
mares. They have made house calls. Overall,
do that. "
they have learned something about accepting the inevitability of death , and maximizHospice as Education
and caring
ing the quality of the life remaining.
"Doctors just don't get good trammg in
"There are a lot of life issue you have to
caring for patients at the end of their lives,"
that before
address," said Piedad. "For the family memsaid Raab. "It's sad what we do to some
bers, too. The spouses and the children.
people at the end of their lives. "
They have to go through the dying process,
The hospice educational program began
you might
too ... You learn a lot of loving and caring
under the state-funded Indirect Medical Eduthat before you might only have shown to
cation Demonstration Project. It now inonly have
your own family."
cludes lectures at the medical school and
Advances in medical techniques and techconsortium hospitals by Hospice Buffalo
nology have raised troubling questions about
medical director Robert Milch, M.D., and
shown to
when efforts to save a life merely prolong a
short- and long-term rotations for residents
and medical students.
painful death. The Robert Wood Johnson
your own
Foundation recently funded a study to deRotations include rounds of the inpatient
termine whether better prognostic informaunit and home visits with a social worker or
tion and patient-physician communication
a clergy member. Students also work with
family."
would prevent overtreatment and pain at the
the bereavement staff, who keep up with
end of life.
families for l3 months after a loved one's
Dishearteningly, the "SUPPORT" study, reported
death in order to provide support for the first-and
in the ov. 22/29, 1995 issue of the Journal of the
hardest-year of loss.
American Medical Association, found that the interThe official hospice training program began in late
ventions did little or nothing to improve care or
1994, but two students paved the way more than a year
outcomes. The study documented that fewer than
earlier. The first was Piedad, whose father , also named
half of physic ians knew when their patients did not
Oscar, is a retired general surgeon in Buffalo.
want CPR,-cand half of conscio us patients were in
The other was Maria Bruno, M.D., then a secondmoderate to severe pain before they died. The article
year student.
states that physicians "p rovide more extensive treat"I had some family members with cancer and bad
ment to seriou ly ill patients than they would choose
illnesses, and I knew people who just weren't satisfied
for themselves."
with the way they were treated. I wasn't sure if it was the

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physicians, or the system in general," said
Bruno, who has just finished her internship
in internal medicine in Buffalo. " ow I think
it's the system in general."
Bruno remembered her grandmother's
death in the 1970s. "It was one of those
situations where they opened her up , found
cancer and closed her up without telling
her ," she said. She thinks the doctors didn't
want to upset her grandmother, but the
result was sending her home without preparing her for the pain that would come.
Bruno did a summer fellowship at Hospice Buffalo between her second and third
years. Once the training program was up and
running, Bruno returned for an elective rotation in her fourth year. She also researched
the literature on physician-patient communication , and assembled a presentation that
is still given to students and residents at the
beginning of their hospice rotations. The
presentation is entitled "Talking about Difficult Subjects: A Survival Guide for Giving
and Getting Bad News. "
"Medicine isn't all about science," Bruno
said. "Hospice medicine is about the art of
medicine as well as the science of medicine. "
The training program got into full swing
when Hospice Buffalo opened its Mitchell
Campus, a complex of low cream-colored
buildings in the Buffalo suburb of
Cheektowaga. The campus includes a lObed unit for hospice patients in the final
stage of disease, a lO-bed nursing unit for
AIDS patients, and a 30-bed skilled-nursing
residence for both
hospice and non-hospice patients with advanced illness. It also
includes a 220-seat
auditorium for conferences and educational activities.
UB residents in
family medicine , internal medicine , and
geriatrics now routinely visit Hospice
Buffalo as part of
their training, ac-

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BUFFALO

"We must

cording to Liora Ziv, R. ., Ed. D. , the organization's director of education. For other
residents, the hospice rotation is available
as an elective. Medical students can also
choose hospice rotations as third- or fourthyear electives.

compassionately communicate to the

F r o m T h eo ry to P ra c ti ce
Medical student oelle M. Stevens spent a
week at Hospice Buffalo last summer. She
remembers visiting a woman who had no
family. The woman had put off seeing a
doctor about the growing hardness in her
breast, and by the time she did, the cancer
had spread.
"She wasn't going to benefit from chemotherapy, " Stevens recalled. "She was living
alone in her apartment and wasn't even able
to get up and go to the kitchen." The hospice
team brought her back to the Mitchell Campus. Before the woman died, she confided to
the student her surprise at the warmth of the
Hospice staff. "She was one of the reasons
why I would like to go into geriatrics, and
why I would also like to continue working
with Hospice in the future, " Stevens said.
The opportunity came sooner than she
had expected. During a hospital clerkship
later in the year, Stevens became friendly
with an elderly woman who had been admitted after a seizure. A CT scan and an MRI
revealed that a cancer had metastasized to
the brain, but its origin wasn't clear.
"The medical team was really set on trying to figure out what the cancer was, "
Stevens said. "They
had a surgical consult coming in , and
they were focused on
trying to cure her. But
they were not focused
on what her wishes
were."
The woman, a retired nurse, insisted
that she didn't want
surgery or chemotherapy, and the family agreed. Stevens
became the interme-

dying patient
and the family
when medical
technology
doesn't have
any more to
offer them
and it's time
to stop. So
many times,
doctors don't
do that."

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diary between the patient and the medical
team.
Stevens advised the
family to make their
wishes known to the
oncologist, and gave
them the Hospice
phone number. The
woman ended up
spending her last days
at Buffalo Hospice. "I
won't forget this lady,"
Stevens said.

unsettling. You don't
know where to sit ... You
find yourself looking at
disease in a totally different way. You look at
the faded pictures on the
wall. At the things on
the coffee table. At the
picture in the wedding
dress. And then you see
the patient in bed, and
you see what the disease
has done. "
The
Life

Students are
Hesitant

Qua lit y

of

When the hospice lessons click, medical stuStudents and residents aren't exactly breakdents and residents no longer feel a sense of
"When you go
ing down the doors for hospice electives.
futility in the face of serious illness. Instead,
They often call for information, then call
they have the skills and the desire to improve
into a patient's
back and say they've changed their mind.
the quality of the life that remains. "In hosLauren Michalakes, M.D., isn't surprised.
pice you don't have the expectation that people
She remembers being an internal medicine
are going to get better, so you don't have that
home, you're
resident a decade ago, intrigued by the techsense of failure that you have in a hospital,"
nology and intellectual challenge of the hossaid Robert Patterson, M.D. , who heads the
on their turf. It
pital. "We used to love intensive care," she
lO-bed inpatient unit.
recalled. "You'd feel like you were doing a
Pain management is a key component of
lot, and you'd write up these wonderful
can be
the hospice training. At the start of rotations,
three-page reports. Being so busy technostudents and residents complete a 39-queslogically, you really didn't have to talk with
tion test to assess knowledge and attitudes
unsettling...
the patient."
about pain, drugs, and addiction. Clinical
During five years of private practice, howpractice guidelines are also distributed. "In
You find
ever, her views changed.
medical school you talk about 15 milligrams
"In the hospital, people die in double
of morphine as a therapeutic dose," said
blaring
rooms with strangers and with C
Patterson. "Sometimes we use up to 4,000
yourself lookon the other TV," she said. "They die with
milligrams of morphine a day to control pain,
their clothes pulled off and hooked up to
and the patients are still responsive; they can
ing at disease
things and all alone."
talk. "
Michalakes remembers sitting with an
A former professor and associate chair of
elderly woman at her home when she died.
in a totally
the OB/G
department at UB, Patterson has
"I just watched her in her big post bed with
been volunteering at Hospice since retiring
all her Ouffy pillows and her daughter and
from obstetrical practice three years ago at age
different way."
husband and her poodle," Michalakes re70. Some days, after putting ina morning at the
called. "What's wrong with that? I felt like I
hospice inpatient unit, he goes home and
spared her something. I felt a sense of accomplishment
babysits his grandchildren and great-grandchildren.
that I hadn't felt in medicine before. "
"In my practice as an obstetrician, I dealt a lot with
She now works full-time at Hospice Buffalo.
families, " he said. "That was one of the joys of mediMichalakes thinks it's important for students to visit
cine. Surprisingly, I feel the same about this .. .. It's two
patients at home. "When you go into a patient's home,
things that happen to all of us-we're born, and we die.
you're on their turf," Michalakes explained. "It can be
Hopefully, we can help at both ends."

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A Sp iri t ual P la ce
"You hydrate a healthy patient, you don't do it for a
Buffalo Hospice medical director Robert Milch started
dying patient," explained Ziv, the education director. "You
his career as a general surgeon with a philosophical bent
can really cause more suffering and pain in exchange for
and a nagging discomfort about modern medicine. He's
maybe prolonging for a few hours the life of the patient."
been increasingly involved in Hospice Buffalo since it
Tchernov said this aspect of hospice went against his
original training. "In my Russian medical school, the
started in 1978, and he gave up private practice several
years ago to serve as its first full-time medical director.
preserving of life as long as possible was the philosophy.
We would never let a patient dehydrate."
"There's something that hearkens to why you became a
physician in doing this kind of work," Milch said. "It's
Stude n ts F i nd Men t o r s
not about dying. It's about how we live."
During his recent visit to Hospice Buffalo, Piedad spotted
Life and death are tightly interwoven at the hospice
Patterson down the hall. He
campus. After traversing a
remembered the older
brick walkway dotted with mephysician's manner, the way
morial stones to former pahe
touched and talked with
tients, visitors arrive at an inis as much a philosophy as a facility
gravely ill patients. "just his
formation desk, where they
voice, you could see them right
can buy shirts, baseball caps,
HosPICE BuFFALO ISBASED at the Mitchell Campus, a
away calming down," Piedad
and other souvenirs with the
$6 m Ilion complex on 20 wooded acres, part of a
hospice logo. There's a sunlit
recalled. "I remember one
pnvate nature preserve in Cheektowaga.
chapel, usually the scene of
time, a patient was very close
But Hospice IS as much a philosophy as a facility.
memorial services, but also the
to
the end. He went into the
More than three-quarters of hospice pat1ents are
place where a patient's daughand held her by the hand.
room
cared for 1n the1r own homes. Medical, nurstng,
ter had her wedding this year.
He
told
her not to be afraid."
counseling, and pastoral serv1ces are prov1ded
Then there's the bulletin board
In a letter to the hospice
through Hospice Buffalo and a networl&lt; of affiliated
outside Milch's office, where
non-profrt agenoes under the umbrella of the Hosstaff after his rotation, Piedad
someone has tacked up a dyp1ce Assooat1on. Serv1ces are also prov1ded in area
wrote: "I was introduced to an
nurs1ng homes and hosp1tals.
ing patient's joke.
aspect of patient care I had
Medicare, Medica1d and maJor nsurance plans
"They say the hearing is the
never seen before. Pet therapy,
will pay for hosp1ce care, and Hosp1ce Buffalo
last thing to go. It's not. It's the
music therapy, birthday paroffers a sliding payment scale for the uninsured.
sex," the woman quipped. A
ties, Christmas gifts, family
According to med1cal director Robert Milch,
dinners, decorated rooms, and
few days later, she revised her
M.D., bereavement serv1ces are an important part
evaluation: "You know what I
the list goes on. I began to
of
hospice care. "It doesn't stop when the mon1tor
realize that the facility treated
was saying about the hearing.
stops. It goes on, and you've got to take care ofthe
more than pain; their treatI think maybe I was wrong. "
surv1vors." Bereavement care, wh1ch lasts 13 months
Death itself, however, is
ment involved quality of life,
after a death, includes counseling and support groups.
resolution of life, family innot trivialized. "It's a very
spiritual place," said Andrei
volvement, staff involvement,
G. Tchernov, M.D. , who bereligious beliefs, personal life
decisions, and bereavement ... I have never seen a team on
lieves the hospice rotation he completed as a resident
will help him in his family medicine practice. His
a unit work so cohesively and with so much heart."
experience also forced him to change his views on
Piedad is now doing his residency in family medicine
and sports medicine at Richland Memorial Hospital in
practicing medicine.
Columbia, SC. Shortly after his visit, Liora Ziv reflected
For example, he learned that hospice professionals are
on the impact of the educational program. "I don't think
willing to withhold interventions that would postpone
we can say yet that we've made a big difference," she
an inevitable death. A hospice patient who suffered a
concluded. "But I think we have made a dent in the
stroke, for example, might use the physical therapy room
surface if people like Oscar come back and say they'll
at the Mitchell Campus to regain the ability to lift a fork.
take what they learned here into their practice." +
But patients near death and with no hope of recovery
Buffalo j ournalist Andrew Danza, a frequent contributor to Buffa lo Physiwould be unlikely to receive antibiotics if they develop
cian, also works as a writer for UB's Department of Family Medici ne and the
pneumonia, or water if they become dehydrated.

L_ _ _ _ _ _

__J

ew Yorh Ru ral Health Research Center.

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SSI How far shouldsdoctors go?

COURT DECISIO S, SE SATIO AL CASES, STATE REFERENDA,

and one-cause crusaders

are dragging the intensely controversial issue of physician-assisted suicide
out of the closet and into the public arena .
...
Whether or not the nation's legal landscape is irrevocably
altered as a result of the controversy, the public mind has
already changed. A topic once taboo is now dissected on
editorial pages and joked about on talk shows. Polls demonstrate increasing support for the idea of physician-assisted
suicide during a terminal or unbearable illness. The new
openness about DNR orders, health-care proxy appointments,
and withdrawal of life-sustaining technologies may also be
making it easier to discuss all sorts of end-of-life decisions.
For the majority of Americans, the figure who has done
more than any other to turn assisted suicide into a public issue
is retired pathologist jack Kevorkian. By May of this year,
Kevorkian had admitted auending 28 deaths, and had been
acquiued in his third trial for assisting in a suicide. At about the
same time, a nationwide Gallup poll showed that 75 percent of
respondents favored allowing a doctor to end an incurably ill
patient's life at the patient's request.
"Public relations-wise, Kevorkian's done a tremendous
job-he's converted a huge egment of the public," said rightto-die activist Derek Humphry, author of the how-to suicide
book Final Exit.
It's the kind of public relations most of the medical community would rather not have. Many doctors-even those who
support physician-assisted suicide-believe Kevorkian is not
qualified to perform it.
They object that he had no experience treating patients
during his career as a pathologist, and that he does not know

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his clients well, does not try to manage their pain, and does
not adequately screen them for clinical depression.
In the end, what many doctors, nurses, and ethicists dislike
the most about Kevorkian is that he does not appear to reflect
at all about his individual cases. Because he believes so
strongly that assisted suicide should be available, they say, he
distributes his treatment without seeming to ask himself if this
option is the right one for this person at this moment.
"Physician-assisted suicide shouldn't be easy. It should
always be a hard decision," said Timothy Quill, M.D., the
Rochester, Y internist who opened a professional dialog on
the subject in 1991 with an admission in the ew England
journal of Medicine that he had prescribed a lethal dose of
barbiturates to a dying patient.
In his account of his eight-year relationship with "Diane,"
Quill described diagnosing her leukemia, discussing her desire for suicide, and asking her to consult her psychologist.
Only when he was convinced that she was acting rationally on
the basis of an unwavering wish, and only after wrestling with
his own emotions, did he prescribe the drugs she requested.
There is no consensus on the morality of physician-assisted suicide. While activists like Kevorkian and Humphry
want to make the practice widely available on compassionate
grounds, opponents argue that it is wrong under any circumstances to take a life. Many doctors also believe that their very
mission prohibits assisting in death.
"It's absolutely appalling that a doctor would take deliber-

.JESSICA

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SUICIDE THREAT IS A

CRY FOR HELP.

OUR ANSWER MUST BE TO

PROVIDE THAT HELP, NOT TO HELP THEM COMMIT SUICIDE. "

Denise Hanlon, R.N., member, NYS Task Force on Life and the Law

ate steps to end someone's life," said Evan Calkins, M.D., a
member of the Buffalo Medical Group and UB professor
emeritus. "It violates the Hippocratic oath to do no harm , and
it weakens the ethical standing of the medical profession. We
are a healing profession, not a killing profession."
Other doctors take a middle view. They feel that before the
American medical establishment considers assisted suicide , it
should learn how to provide good end-of-life care for all dying
patients. If assisted suicide is to be an option, they say, it
should be decided as Quill and "Diane" decided it; not in the
courts or on the editorial pages, but one case at a timecarefully, deliberately, and with anguish.
Even some opponents respect Quill.
"If all doctors were like Quill , then this wouldn't be a great
concern," said Denise Hanlon, R.N. , an opponent of physician-assisted suicide who serves on the ew York State Task
Force on Life and the Law.
"Or if all patients were like 'Diane.' But they're not. "
The l aw

The courts and state legislatures are the current forums for
debate about physician-assisted suicide. The 1994 Oregon
"Death with Dignity" law is the first in the country to explicitly
condone physician-assisted suicide, although legal challenges
have so far prevented it from going into effect.
In March 1996, the Ninth Circuit Court of Appeals, a
federal court in San Francisco, overturned a State ofWashington law that banned assisting in a suicide.
The plaintiffs were four physicians, three terminally ill
patients who died before the ruling, and a non-profit organi-

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zation called Compassion In Dying.
The court broke new ground by determining that the U.S.
Constitution guarantees a "right to die;" that is, to choose the
manner and time of one's own death. Depriving patients of
that right therefore violates the due process clause of the 14th
Amendment. The court wrote that doctors should be able to
prescribe life-ending medication for terminally ill, competent
adult patients who want to hasten their own deaths.
The judges said that their decision , in essence, removed
them from the issue. "We are following the constitutional
mandate to take such decisions out of the hands of the
government, both state and federal , and to put them where
they rightly belong, in the hands of the people. "
The ruling has the potential to affect California , Washington , and Oregon, which all fall under the jurisdiction of the
Ninth Circuit Court.
In a similar ruling on April 2, the Second Circuit Court of
Appeals, with jurisdiction over ew York, Vermont, and
Connecticut, struck down part of ew York's ban on assisted
suicide. The case was brought by three terminally ill patients
and three doctors, one of whom was Quill. The patients all
died before the ruling.
The judges ruled that a doctor can prescribe drugs to
hasten the death of a competent, terminally ill patient at the
patient's request. They explained their decision in
commonsense language: "What interest can the state possibly
have in requiring the prolongation of a life that is all but ended?
And what business is it of the state to require the continuation
of agony when the result is imminent and inevitable?"
legally, the rationale was more complicated. It was de-

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�"IF WE DON'T HAVE ANY LEGAL WAY TO DO TH I S, THEN IT TURNS
INTO ONE DOCTOR MAKING THE HARDEST TREATMENT DECISION
POSSIBLE IN A

VACUUM -

WITHOUT CONSULT I NG ANYBODY , WITH-

OUT DISCUSSING IT . THAT TO ME IS NOT GOOD MEDICINE. "

Timothy Quill , M.D., plaintiff in Quill v. Vacca

cided that the ban violated the equal protection clause of the
14th Amendment.
All patients already have the right to hasten their own
death by refusing medical treatment. However, the argument
goes , terminally ill patients who were not being kept alive
through medical intervention had no comparable way to
hasten their own death .
lf patients can essentially commit suicide by refusing
treatment,Justice Roger]. Miner wrote, "they should be free
to do so by requesting appropriate medication to terminate life
during the final stages of terminal illness. "
Stil l a crime
While these rulings are being appealed to the U.S. Supreme
Court, and while Oregon's law remains entangled in the
courts, it remains a crime for doctors to assist in suicides.
Yet it's clear that they are doing it anyway. An anonymous
survey recently published in the journal of the American Medical
Assodation found that a small percentage of doctors in Washington state had helped terminal patients who wanted to die.
A survey of Oregon doctors published in the N E]M in February
showed that 7 percent of respondents had assisted in a suicide.
Forty-six percent of the respondents said they might be willing to
assist in suicides if the practice were legal, and 31 percent said they
would refuse on moral grounds.
"l think the issue at this point is how to respond to
physician-assisted suicide , not whether it's going to happen ," said Stephen Wear, Ph.D ., co-director of UB's Center
for Clinical Ethics and Humanities in Medicine. "Whether or
not the legal situation allows it, it's happening, and in some
jurisdictions it's likely to become legal. "

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Does the law matter?
Timothy Quill firmly believes that liberalizing the law is
necessary to protect doctors like himself who choose to help
patients die.
But jack Freer, M.D. , chair of Millard Fillmore Hospital's
ethics committee, uses Quill's case to prove that the law is
already practically powerless to touch doctors. After Quill's
E]M letter, prosecutors referred the matter to a grand jury,
which refused to indict him.
"They couldn't indict Quill. Kevorkian is unconvictable,"
Freer said. "lf that's the case, if you can't be convicted, then
[the legal decisions] don't matter because you don't need extra
protection. If a doctor acts in good faith, if it is clear that
someone is suffering and asks for help, then that physician is
unlikely to be prosecuted, anyway.
"There would have to be a compelling need in order to
justify such a sweeping change in the status quo. l don't see
that need, especially when the change would jeopardize so
many vulnerable people who have not availed themselves of
good palliative treatment," Freer added.
P u b lic debate?
Quill and some other activists argue that since the practice is
happening, it is important to discuss it. His purpose in writing the
NE)M letter and joining the Second Circuit Court lawsuit was to
open up discussion on what he felt was a widespread practice.
"lf we don't have any legal way to do this, then it turns into
one doctor making the hardest treatment decision possible in
a vacuum-without consulting anybody, without discussing
it. That to me is not good medicine," Quill said in a recent
interview with the Buffalo Physician.

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"IT'S ABSOLUTELY APPALLING THAT A

DOCTOR WOULD TAKE

DELIBERATE STEPS TO END SOMEONE'S LIFE. WE ARE A
PROFESSION, NOT A

Iif e

HEALING

KILLING PROFESSION."

Evan Calkins, M.D., UB professor emeritus

ew Yo rk State Attorney General Dennis Vacco (UB Law
School class of 1978) is leading the appeal because he feels
allowing doctors to take life is wrong, and that vulnerable
patients could be pressured into suicide for economic or other
reasons. He also fears that ew York could become home to a
sort of cottage industry of commercial death clinics.
But even if he succeeds in getting the U.S. Supreme Court
to uphold the ban on assisted suicide, Vacco does not plan to
launch a drive to prosecute doctors- such as Quill- who have
admitted doing it.
"I don't think we need to change the prosecutorial scheme,"
he told this magazine. "No law can eliminate proscribed
behavior, but the deterrent would discourage a sufficient
number of professionals from engaging in this conduct.
"I think that the system we had until this decision was
working well. "
Public po li cy

Doctors, nurses , lawyers, ethicists, and members of the
clergy from around ew York State meet once a month as
part of the ew York State Task Force on Life and the Law to
wrestle with some of the hardest questions in health care.
Some of the task force's recommendations have led to ew
York's health-care proxy law and the Family Care Bill, which
has not yet been passed into law.
The group's 1994 report When Death is Sought recommended against decriminalizing physician-assisted suicide.
Some members of the task force felt that it was inherently
wrong to take a life. Others felt that it was unethical for a doctor
to do so. A third group felt that in some cases, providing a
quick death for a terminal patient who asked for help would be

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compassionate and ethical.
The task force was in agreement, however, in concluding
that legalizing physician-assisted suicide would be dangerous
public policy. The cost of health care and the perceived value
of the patient could come to bear on who ends up committing
suicide , they cautioned. They were also concerned that patients would not be properly referred for psychiatric or palliative care, and that attitudes about assisted suicide might
become casual.
"Over time, as the practices are incorporated into the
standard arsenal of medical treatments, th e sense of
gravity abo u t the practices would dissipate," the task
force warned.
Also opposed to physician-assisted suicide are professional
medical societies, including the American Medical Association, which say that it violates a doctor's mission, and some
religious groups.
"It's a non-negotiable with us," said Sister Sally Maloney, a
vice president at Mercy Health System of Western ew York,
a Catholic hospital group. "It's completely opposed to our
commitment to life. The ethical directives by the Catholic
bishops are very clear on that. "
Good end-of-l i fe care

Since 1978, Hospice Buffalo has cared for more than 13 ,000
dying patients.
Only one has committed suicide, according to medical
director Robert Milch, M.D.
"It's not unusual for us to go into a patient's home and hear
that patient say, 'Look, doc, if things get too bad, I've got the

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usually they're looking forreassuram:e on rwo-points: one,
that you can take care of their symptoms and their pain; two,
that they will not be alone."
"These fears are what drive people to consider suicide. lf
you support patients and families, if you address their needs
and fears, then the urge to do self-harm essentially disappears," he said.
However, study after study has shown that doctors often
fail to control patients' pain.
"lf l make someone uncomfortable enough, put them in
enough pain, l can convince them of anything," Milch said.
"That is the principle of torture.
"l would rather establish as a standard that the presence of
unassessed, unmanaged pain is prima facie evidence of incompetence on the part of the physician," Milch continued. "lf
physicians can't manage physical suffering, why would we
give them the ability to do omething even bigger-end a life? "
For Milch, and many other , physician-assisted suicide is at
best a glamorous distraction from discussion of the real needs
of terminal patients, and at worst a quick fix that society finds
easier than spending the time, money, and emotional energy
necessary for good care of the dying.
"A suicide threat is a cry for help," said Hanlon, an adjunct
professor at the UB School of ursing. "These people are in an
impo iblesituation and they don't know what to do. They fear
the unknown, and they fear that they won't get the help they
need. Our answer must be to provide that help, not to help
them commit suicide."
But for Stephen Wear, the lack of good palliative care itself

becomes an argument in favor of legalizing assisted suicide.
"lf we can make people feel that they won't be needlessly
overtreated and that their pain will be managed-and right now that
is nota reasonable expectation, and people know it-then we should
agree with Milch. lf we can't, then for compassion's sake we should
be with Kevorkian and Humphry-and I loathe saying that," Wear
said. "But it isn't enough to make philosophical arguments against
assisted suicide. Doctors have to change their practice so assisted
suicide is no longer the compassionate alternative."
Even in the best scenario, where palliative care eases
symptoms of terminal disease and hospice-type programs
support patients and their families, many people believe that
there will still be patients who cannot be helped by medicine.
"ln most patients we can relieve their suffering, and we
have to get better at doing that," Freer said. "But l also think
it's clear- and most doctors agree-that there are people
whose suffering cannot be relieved. There are people whose
suffering can only be relieved by ending their lives."
A s l i ppe r y slope

The recent legal decisions on assisted suicide have made a
distinction between helping a patient take his or her own life,
and actively taking the life of a patient through euthanasia.
But many fear that condoning one will lead to the otherand worse, to euthanasia of patients who are incapable of
consent. ln the etherlands, euthanasia is illegal, but is not
prosecuted if doctors demonstrate that the patient explicitly
requested euthanasia, document their actions, and stay within
other guidelines established by the national medical society.

"IF PHYSICIANS CAN'T MANAGE PHYSICAL SUFFERING, WHY
WOULD WE GIVE THEM THE ABILITY TO DO SOMETHING EVEN
BIGGER-END A

LIFE?"

Robert Milch, M.D., med1cal director, Hospice Buffalo

®

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�"THE PROBLEM WITH THE PHYSICIAN-ASSISTED SUICIDE QUESTION
IS THAT IT DISTRACTS FROM REAL ETHICAL DILEMMAS IN
MEDICINE, AND COMPASSIONATE CARE OF DYING PEOPLE. "

jack Freer, M.D., ethics committee chairman, M illard Fillmore Hospital

Law might be the group that could provide leadership on the
issue ," said Quill.
Hanlon responded, "We will investigate any topic the
governor tells us to, but we have already looked at this topic
and come up with recommendations on it. " The task force's
report warned that it would be impossible to draw up guidelines that could not be bent or broken.

However, at least one study there has shown that more than
one-fourth of euthanasia deaths occurred without a specific
request from the patient. Many argue that this proves legalizing
assisted death for consenting patients can lead to officially
sanctioned euthanasia of patients who are incapable of consent.
Also, Milch points out, "Nothing in medicine is a sure-fire
bet. " If some physician-assisted suicide attempts fail to kill the
patient, he asks, would that lead to sanctioned euthanasia?
"Whose responsibility will it be to administer the coup de grace? "

W h o w ill dec i de ?

For the moment, the courts are making the decisions. If they
decide to decriminalize physician-assisted suicide , the resulting legal void could open up more questions than it answers.
The medical profession and American society as a whole will
then have to decide how to handle the new freedom-to use
it, abuse it, or reject it.
"We're a complex society , a society of tensions, and there
are not very many things that have a clear 'yes' or 'no' answer
anymore, " Wear said.
Also remaining to be solved is the issue of giving the proper
care to dying patients-educating doctors and allocating resources. Whatever their opinion on physician-assisted suicide, observers believe that improving end-of-life care would
drastically reduce the number of patients who find life so
unbearable that they would choose suicide.
"The problem with the physician-assisted suicide question is that it distracts from real ethical dilemmas in medicine , and compassionate care of dying people ," said Freer.
"It's just such a simplistic way of dealing with such a small
number of people, when the focus should be on the vast
majority whose pain we just are not treating. " +
jessica Andur is the editor of Buffalo Phy sician .

T i me for gu i de li nes ?

Some believe that the potential loosening of assisted-suicide
laws means that it is time for medical professionals and patient
advocacy organizations to cooperate in setting up guidelines
to provide direction and protection for both groups.
"We need guidelines and rules so people know that if they
dot their i's and cross their t's, they can do this out in the
open ," Quill said.
His recommendations for safeguards include ensuring
that a patient who elects suicide is terminally ill and not
clinically depressed; that the patient is not pressured into the
decision; that the wish to die is not a transient one; that there
is proper access to palliative care; and that a second opinion
is sought from an independent practitioner who has expertise in caring for dying patients.
Quill's first concern is that palliative treatment and hospice
care be extended to all who need it. "Hospice care must have
failed , or not be acceptable to patients , before they should be
able to choose assisted suicide. "
He suggests that safeguards would have to be passed into
law at the state level. "The state Task Force on Life and the

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by Scott Thomas

Four Buffalo doctors discuss
the care of the dying

BLACK A D WHITE

aren't options for the physician caring for a patient in the final stage

of life. All decisions are made in the gray zone in between.
These shades of gray were the topics of a panel discussion, "Confronting Difficult
Emotional and Ethical Issues in the Care of the Dying" at the 59th annual Spring
Clinical Day, moderated by Elizabeth L. Maher, M.D. '85. The panelists were:
Martin Brecher, M.D. '72, chairman of pediatrics at Roswell Park Cancer Institute and

chief of hematology oncology at Children's Hospital.
Jack P. Freer, M.D. '75, an internist and ethicist at Millard Fillmore Hospital who teaches

at UB Medical School.
Ross G. Hewitt, M.D., medical director and principal investigator for Erie County

Medical Center's immunodeficiency services.
Robert A. Milch, M.D.

'68, medical director of

Hospice Buffalo.
Case No. I: A 36-year-old HIVpositive homosexual man. Following
complications of AlDS, he began to
develop memory loss . He made his
partner his health care proxy and
told his family in Wisconsin of his
illness . When he was hospitalized for
PCP pneumonia, his mother demanded that he be intubated for respiratory distress over the proxy 's objections.
Hewitt: When the family is not
aware of the diagnosis until much

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�Care of the dying

later in the course of the disease, it puts patients and
perhaps their significant others literally years ahead in
terms of acceptance of the situation, coming to grips
with their loss, the realities of having AIDS. They've
gone through that process and are probably at a better
stage to make health care proxy-related decisions on
CPR and life support. So now the family is faced with
going through all of those same processes that the
patient has already been through years earlier. That
very often leads to conOicts regarding care at the end
of life. I think it's very possible in this particular case
that the mother is still in shock and not able to listen
to the facts that we might present in terms of what the
prognosis is.
Freer: This also points out the importance of a health
care proxy, particularly in situations where there may
be a number of different friends and family who may
have conOicting views about what is best for the
patient. This is in part because of the legal climate and
the popular culture both presuming that people would
want everything done to keep them alive as long as
possible unless they've said otherwise . With that
presumption, if you had somebody like the parent
coming in and saying 'yes , you'd better intubate that
person,' that is in keeping with this predominant view
within the hospital culture and the courts, and there-

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fore it's important to have somebody who has the
legal authorization to make decisions like this.
Milch: Sometimes it's helpful to word things just a little
bit differently. I've always been uncomfortable with
defining ventilation and things like that as "life support." I think the connotation of discontinuing "life
support" weighs heavily down the road, and if we
redefine them as "function supports"-that's what we're
doing with the ventilator is supporting the failed function-then perhaps that could be part of the first step
over the bridge.

Case No. 2: A 4-year-old boy with Stage 4 neuroblastoma. After chemotherapy, he had remission until age 6,
and with a bone marrow transplant did well for another 18
months. At this point the mother requested no aggressive
therapy. He was hospitalized for seizures, and required
progressively larger doses of Phenobarbital to control
them; hospital staff objected to giving such massive doses,
and reported the case to administrators.
Brecher: When a family faces potential loss of a child,
perhaps this is the greatest tragedy that one can face in
life. The family is really never the same thereafter. The
parents are faced with this overwhelming tragedy in
their lives; the siblings, who are sometimes forgotten
elements in all of this , are profoundly affected by the
parents' full attention on the sick
child. The grandparents sometimes
feel left out of the loop, and of course
they're heavily emotionally involved.
There's a tremendous impact on all
the family.
After the child dies , this family is going to have to live with what
went on for many years to come
and hopefully feel comfortable, not
with the death of the child, but
with what went on, that everything
that should have been done was
done correctly.
There is such a loss of control
when something dreadful happens
to your child. After all, these are
parents who used to decide what
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�and suddenly it seems like everything has spun out of
control and they have no impact at all on the course of
their child's life. And to be able to bring that into the
care-giving aspect of things , to have the child at home
with as much support as they need , makes them feel
that they have an important pan in this and gives them
more comfort about a terminal situation.

tain level , we relieve some of their bone pain, we
improve their exercise tolerance or what have you.

Brecher: The issue of the emotional impact on the
care-givers is an important one. The longer you work
with a child and a family , and the more you get to know
them , the more they become a part of your life and the
more difficult it is if there's suddenly a bad turn of
events.
Freer: Cases like thi also raise an important point for
l think the after is important, too , sticking with the
people involved in medical education. These are very
family. I've had families tell me that not only was losing
complex, difficult cases in terms of medical managethe child difficult, but they
ment, in terms of commuhad devoted so much of their
nication, in terms of settime and so much of their
ting where the patient is
life
energies for months or
going to be cared for. And
years to the care of this child
yet there is still that rem"I'VE HAD FAMILIES TELL ME
that suddenly there was this
nant of the old medical
incredible void , when even
education system where
THAT NOT ONLY WAS LOSING
though they might have
cases like this are not inthree other kids, they didn't
teresting, they're not good
know
what to get up for in
teaching cases. l still get
THE CHILD DIFFICULT , BUT
the
morning.
infuriated when l see patients drop off the teach Milch: Even our choice of
THEY HAD DEVOTED SO MUCH
ing curve when they go to
words is significant. On the
hospice or a palliative care
one hand we have "do not
plan. These are very comOF THEIR TIME AND SO MUCH
resuscitate, " on the other
plicated management ishand we have "aggressive. "
sues, and maybe we have
Why
would we refer to it as
to emphasize this in trainOF THEIR LIFE ENERGIES FOR
an
aggression,
rather than
ing.
trying to examine it as someMONTHS OR YEARS TO THE
Milch: The issue of whether
thing that may or may not
a patient does or does not
be appropriate to a certain
have a do-not-resuscitate
clinical setting7 l am as
CARE OF THIS CHILD THAT
order is but a small commuch troubled by standing
orders of daily blood draws .
ponent in his overall plan
To what end? lt doesn' t imfor care, and should really
SUDDENLY THERE WAS THIS
pact our therapies. Then
be kept to the side of deciperhaps it's appropriate to
sion-making. The plan of
INCREDIBLE VOID. "
examine that. CAT scans,
care is daily reassessed ,
MRls, other procedures ofeven hourly reassessed .
ten do little more than docuYes , we would transfuse
Martin Brecher, M.D.
ment
the natural progrespatients with metastatic
sion of disease and do not
prostate cancer, for example , if in getting their
affect our decision-making
hemoglobin up to a cerprocess. +

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se

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explains how we die
by Scott Thomas
OTHI G E~E,"

said Sherwin B.
uland, M.D., "we should teach them that they must never
let their patients lose hope."
Hope-an elusive concept, and one that might seem to
have more to do with poetry than with the science of
medicine. Yet uland, who delivered the Stockton Kimball
Memorial Lecture at the 59th annual Spring Clinical Day on
May 11, told a large luncheon audience that hope is a most
critical component of care at the end of a patient's life. As
death approaches, he said, the role of healer and counselor is
most important, not the science of T-cells and high-tech
machines.
Nuland, a clinical professor of surgery at
the Yale University School of Medicine, is
best known for his 1994 book How We Die,
a frank and anecdotal account of life's last
chapter as he has seen it played out in his
family and his patients. The book won the
ational Book Award for nonfiction and the
Book Critics Circle Award, and was a finalist
for the Pulitzer Prize.
Though the ideas of hope and approaching death may seem irreconcilable, uland
offered three ways in which a dying patient can be given the
gift of hope.
He was once asked, "What is the worst way to die?" His
response was, "Alone"-whether physically alone or emotionally isolated. "Hope becomes a promise," he said, "that
we will let no one die alone."
Second, uland said, hope is the promise that no extraordinary measures will be taken that will make things worse.
And finally, he said, physicians can impart the hope for
immortality. "I don't believe in an afterlife," he said, "but I do
believe in immortality. There are, for each of us, maybe one,
maybe five people whose lives are dependent on what we are.
We can share with them what their existence means for us.
That's the kind of immortality that I would cherish." A person's
actions and life affect loved ones for years and perhaps
generations. Thus, a life well lived confers immortality.
uland also quoted Czech President Vaclav Havel: "Hope
is not the belief that things will turn out well. It is the belief
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that things will make some sense however they turn out."
Nuland recounted the circumstances that led him to
write How We Die-a persistent literary agent, a family
history touched by many early deaths. "Death had been part
of the lore of my family," he said. "Going to medical school
meant learning to understand, to take part of the mystery
away."
In his practice he realized that most of his patients had
no concept of what life's final stage was like, medically or
emotionally. Romanticized Hollywood images of the family
patriarch dispensing pithy wisdom from his deathbed, or
the beautiful young woman going peacefully into that good night, are all we have to
go on, he said. Hence his unflinching collection of stories about how real people die,
sometimes easily and quietly, sometimes in
pain or unable to resolve their life's unfinished business.
uland pleaded for his fellow physicians
to pay close attention to comfort care for
their dying patients. "How did physicians
forget that even more important than saving
life is the duty to relieve pain?" he asked.
"When did we begin converting every ethical and moral
decision into a clinical decision? How have we begun to
value triumphs of technique over triumphs of reason?"
He traced the genesis of that attitude to the entrance of
molecular biology into medicine. "We began teaching our
students that one can learn more about a patient through
the proper tests than by developing a real relationship with
the patient. We moved farther and farther away from the
fellow human beings who came to us for help, and before we
knew it, we no longer knew who they were."
But, uland argued, it benefits the practitioner as well as
the patient to embrace a more human connection. "Among
the greatest rewards we derive from medicine," he said, "are
those we derive when we get emotionally involved with the
people who come to us for healing." +
Thomas, a frequent contributor to Buffalo Physician, is an editor and
freelance writer with specialties in medicine, the arts, and religion.

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�The historic context ot medicine

Nationwide history of m edicine meetings draw scholars to Buffalo
B Y JESSICA ANCKER

for thousands of years, but in every age societal prejudices have
colored their interpretations of th ose observations.

H EALERS HAVE MADE ACCURATE MEDICAL OBSERVATIO S

This lesson was a recurrent theme at
the national meeting of the American
Association for the History of Medicine,
which was held in Buffalo May 9-12 in
honor of UB's sesquicentennial. The
event drew more than 400 scholars from
around the country to the Hyatt Regency Buffalo.
In the keynote address, Thomas
Benedek, M.D., a rheumatologist and
the president of the a sociation, discussed medical theories on the occurrence of gout in women.
"The story of gouty women is an
example of the interaction of science
and the society in which it is practiced.
It should not be considered unique,"
Benedek cautioned. "Despite our tremendous advances in science and technology, an unexpected stress makes us
retreat to moralizing."
Gout is caused by high levels of uric
acid, which is produced by the metabolism of purine. The disease is characterized by sudden attacks of pain, swelling,
and stiffness of the joints, often in the
feet and legs. Inheritance, overeating,
and alcohol can play a role in triggering
the illness. Because estrogen help
women excrete uric acid more efficiently
than men, premenopausal women rarely
suffer from gout.
Ever since the 4th century B.C.,
Benedek said, healers have noticed that
gout is rare among women. The earliest
known pronouncement on the disease"A woman does not take the gout unless
her menses be stopped"-is attributed
to Hippocrates himself.
The Roman writer Seneca blamed the
disease on licentious and intemperate
lifestyles. While these activities may have
been regrettable in men, Benedek said,
they were considered despicable in

®

women. "Because of their vices, women
have ceased to deserve the privilege of
their sex; they have put off their womanly nature and are condemned to suffer
the diseases of men ," Seneca wrote in a
passage echoed by doctors for centuries.
An 18th-century comic poem played
on the alleged connection with lechery:
"Where does one see a wife irate
Because her spouse suffers gouty feet?
In hot passion's embrace, as e\·e1yone /mows,
Tl1 e gouty most often arc mighty heroes!"

Doctors trying to explain gout in
apparently blameless men and women
offered alternate explanations. A few
speculated that gout could be inherited
from ancestors. Others held that gouty
symptoms were not always gout. One
doctor wrote that slender women with
symptoms of gout were really suffering
from hysteria. In the 18th century, the
prestigious Philadelphia doctor Benjamin Rush absolved a respectable
woman patient of the imputation of

indelicate behavior by calling her gout
rheumatism.
"The cultural response to gout meant
that women with gout were scorned:
doctors often believed it was due to their
unacceptable behavior," Benedek said.
"The same thing happened when AIDS
appeared. That shows how helpful it is
for doctors to know something about
the history of medicine-it helps them
better analyze new problems that they
encounter."
The 69th annual meeting of the American Association for the History of Medicine drew 66 papers. The Society for
Ancient Medicine, the AIDS History
Group, the American Veterinary History
Society, the American Association for
the History of ursing, and seven other
affiliated history societies also held their
meetings in Buffalo the same weekend.
Papers covered a multitude of topics,
including fetal alcohol syndrome, the
treatment of insanity in the 19th century, medical scholars in medieval Paris,
traditional Korean medicine, the polio
vaccine and public health policy, and
dissections in the paintings of
Rembrandt. +

UB history professor Jomes Bono, Ph.D. (left), coordinated local affairs for the national meeting of the
American Association for the History of Medicine, May 9-12 in Buffalo. Thomas Benedek, M.D. (right), of
Pittsburgh, PA, is the association president.

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•••••••••• •••

~
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Dean Naughton to stay
for additional six months
ohn P. aughton, M.D. , the dean of
the medical school and vice president for clinical affairs, has agreed
to keep his current posts until the
end of the year.
aughton said he had planned to
retire in June, but agreed to stay on for an
additional ix months while the search for his
successor continues.
"As always, I appreciate your everwillingness to respond to the needs of the
university," Provost Thomas Headrick
told the dean.
"UB greatly appreciates John's dedication and willingness
to serve the university," UB President
William Greiner said.
After his retirement, aughton will
John Naughton
likely be as busy as
ever. He plans to teach, do research in
cardiology, and get involved in other
educational projects.
"''ve begun my transition by teaching
a course in health care organization, and
I'm continuing my activities in graduate
medical education reform, and immunology and heart disease," he said. +

Endowment established for
scholarships and awards
\
J

director of admissions and the scholarship committee, I
see the tremendous
financial need of
nearly 50 percent of
the school's medical
students. It made me
realize how crucial financial assistance is
to these students. " +

ophthalmology. Recipients will be chosen on the basis of
academic standing
and financial need.
"1 owe my success
in medicine to UB, and
1 appreciate the opportunities I received
when 1 was a student,"
saidGuttuso " ow, as Thomas Guttuso

Registrar Dick Jones organizes the 1996 graduates in the Center for
the Arts atrium.

Twenty-nine members of the doss of 1946-who graduated during UB's centennial-returned to help the school
celebrate its sesquicentennial.

scholarship and award fund for UB
medical students has been established
through a gift of residential property
from Thomas]. Guttuso, M.D. '60,
the medical school's director of admissions, and his wife, Barbara.
The Dr. Thomas ]. and Barbara L.
Guttuso Scholarship and Award Fund
will provide an annual scholarship for
four medical students, as well as an
award for a senior with an interest in

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Timothy Y. Jordon, M.D., was the
class speaker at commencement.

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································································

.

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Match Day 1996
UST U DER HALF ofUB's graduatin g class ( 49 percent) were placed in
primary care residencies in this spring's Match Day, putting the university within a hair of its 50 percent goal.
The

ational Residency Matching Program results were announced

March 20 by associate dean Dennis

adler at the Lord Amherst Motor Hotel.

Eighty-two percent of the 136 graduating UB students got their first,
second, or third choice of residency. Thirty-one percent will remain in
Bu ffalo to train in UB's Graduate Medical Dental Education Consortium,
while 53 percent will go out of state.

JOHN l. BUTSCH, Stngfl), Rush-

Presbyterian-St. Luke's Medical
Center, Chicago, IL
LAWRENCE R. CANFIELD, Famil) Practice,

niversity of ew Mexico, School of
Medicine, Albuquerque, M
RICHARD E. CHARLES, lnccmal Medicine,

The list below includes fou r additional students who were matched on

UB Graduate Medical Dental
Education Consortium, Buffalo, NY
KATHERINE B. CHATIGNY, Psychiauy,

Umversity of ew Mexico, School of
Medicine, Albuquerque, NM

Match Day but were not graduating seniors.
Of the primary care specialties, 15 students went into internal medicine
and four chose internal medicine-primary care. Twenty-two students chose

BASIL CHERPELIS, Internal Medicine

(P1clim.), orth Shore Universit)
Hospital, Manhasset, Y
KRISTEN M. CHRISTIAN, Pediatrics, S

Y
Y

Health Science Center, Syracuse,

pediatrics, 21 went into family medicine, and seven chose med!peds.
EILEEN

(Primal) Ca1c), Emory Universit)'
School of Medicine, Atlanta, GA

Universi ty of Michigan Hospitals,
Ann Arbor, Ml

SARAH BALLOW, Pediatrics,

KIMBERLY M. BONISCH, Pediatrics,

Graduate Medical Dental Education
Consortium, Buffalo, NY
Jo ANNE ARNOLD, Obstetrics &amp;

Gynecology, UB Graduate Medical
Dental Education Consortium ,
Buffalo, NY
PETER AUGUSTINOS, Surgery, St. Elizabeth's

Medical Center, Boston, MA

UB Graduate Medical Dental
Educauon Consortium, Buffalo,

Y

JOHN P. BARRETT, Obstetrics &amp;

Education Consortium, Buffalo.

Gynecology, Womens and Infants
Hospital, Providence, Rl

MARY(. BOPP, Pcdiauics, UB Graduate

Medical Dental Education Consortium, Buffalo, Y
RENIER J. BRENTJENS, lntcmal Medicine,

University of Virginia,
Charlouesville, VA
MICHAEL BEECHER, Medicine/Pediatrics ,

UB Graduate Medical Dental
Education Consortium, Buffalo, NY
SUSAN E. BEHR, Pediatrics, Univer it)' of

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TIMOTHY M. ComR, Diagnostic

Radiology, Univcrsit) of Chicago
Hospital, Chicago, IL
HOLLY H. CROMWELL, TlansJtional, Cook

County Hospital, Chicago, IL

F. DAVIS, Internal Medicine, LOS
Hospllal, Salt Lake Cit)', UT

ALLEN

GINA R. BRESCIA, lntcnwl Medicine,

BRADLEY R. DAVIS, SurgCI), University of

Yale- ew Haven Hospital, New
Ha,·en, CT

(P1immy Care), University of
Rochester, Strong Memorial Medical
Center, Rochester, NY

SALVATORE BIANCO, Family Practice,
Spartanburg Regional Medical
Center, Spartanburg, SC

Y

Yale- ew Haven Hospital, ew
Haven, CT

PAUL C. BURNS, lntcnwl Medicine

Texas Medical chool. Houston, TX

Radiolog), Universit) of Rochester,
Strong Memorial Hospital,
Rochester, Y
STEPHEN R. COOK, ,\fcdicinc/PcdJatrics,

UB Graduate Medical Dental

MATIHEW f. BARTELS, Pediatrics,
DAVID ANDERSON, Surgery (P1elim.), UB

M. BOBEK, Emergency MediciltC,

ONEIL BAINS, lntcmal ,'1-fcdicine

mversity
Health Center, Piusburgh, PA

JOSEPH E. CHRUSCICKI, Diagnostic

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Cincinnati Hospital, Cincinnati, OH
JOSEPH S. DEJAMES, Family P1actice, UB

Graduate Medical Dental Education
Consortium, Buffalo. NY
MANNY A. DELUCCA, Pediatrics, Medical

College of Virginia, Richmond, VA

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Rhode Island Hospital,
Prolidence, Rl

(LARA E. KIM, lntemal Medicine,
University of Nonh Carolina
Hospital, Chapel Hill, NC

MEEGHAN A. HART, Pediatrics, UB
Graduate Medical Dental Education
Consortium, Buffalo, Y

ANDREW B. KLAFTER, Psychiatry,
Thomas jefferson University,
Philadelphia, PA

STEVEN G. HEINTZ, Family Practice,

ANTHONY J. LANGONE, lntemal Medicine,

University of Vermont, College of
Medicine, Milton, VI

Baylor College of Medicine,
Houston, IX

JASON K. Ho, Family Practice,

KEUNG W. LEE, In/ental Medicine, Yale-

Glendale Adventist Medical Center,
Glendale, CA

MATTHIAS K. LEE, Psychiatry, Stanford

BRIAN HANLON, lntemal Medicine,

ROB L. DEMURO, lntmwl Medicine

Dermatology, Stony Brook Teaching
Hospitals, Stony Brook, NY

(Primar) Care), Bassett Healthcare,
Cooperstown, 'Y

JAMES W. FOIT, Family Practice, UB

DAVID J. D'SOUZA, Diagnostic

Graduate Medical Dental Education
Consortium, Buffalo, NY

RadwlogJ, UniYersity of Texas
Medical School, Houston, IX
KATHLEEN M. DYSON, Pediatncs, UB

RICHARD A. EDWARDS, Obstetncs &amp;
Gynecolog_1, UB Graduate Medical
Dental Education Consoruum,
Buffalo, NY

LLEWELLYN A. FOULKE, Patlrologj,

Hospital of the University of
Pennsyh·ania, Philadelphia, PA

UniYersity of Cincinnau Hospital,
Cincinnati, OH
MICHAEL J. ENDL, /rue mal ?lfedrcinc

(Prelim.), Sisters of Charity Hospital,
Buffalo, NY; and Dwgnostic
Radiolog) , Duke Uniwrsil) Medical
Center, Durham, C
JOSHUA J. FISCHER, /ntemal Medicine,

Universit) of Virgmia,
Charlonesnlle, VA

SAMUEL GOODLOE, Surgery• (Prelim.), UB
Graduate Medical Dental Education
Consortium, Buffalo, Y

Gynecology, SU Y Health Science
Center, Syracuse, NY

THOMAS J. GUTTUSO, lntemal Medicine

Einstein College of Medicine,
Montefiore Medical Center, Bronx,
y
ERIK J. JENSEN, lntemal Medicine, UB
Graduate Medical Dental Education
Consortium, Buffalo, NY

PATTI A. HAMERNIK, Pediatrics, UB

TIMOTHY JORDEN, General Surger),

GINA l. FLORES, Far111/; Practice, New

STEPHANIE C. HAN, lrllcntal Medicine

Hampshire-Dartmouth Famll)
Practice, Hanover, H

(Prelim.), UB Graduate Medical
Dental Education Consortium,
Buffalo, Y; and Radiation Oncolog),
Yale- e\\ Haven Hospital, New
HaYen, CT

(Prelim.), Ston) Brook Teachmg
Hospitals, Ston) Brook, Y; and

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PAULY. JEE, lmemal Medicine, Alben

(Prelim.), University of Rochester,
trong Memorial Hospital,
Rochester, NY; and 1 curolog),
University of Rochester, trong
Memorial Hospital, Rochester, Y

Hospital at Queens, Flushing, NY

SCOTT L. FLUGMAN, lmernal Med1cine

BABAK JAHAN-PARWAR, Research
Fellowship, Swgical Pa!holog),
Roswell Park Cancer Institute,
Buffalo, Y

CHRISTOPHER JAYNE, Obstetrics &amp;

Graduate Medical Dental Education
Consortium, Buffalo, 1Y

DORNA E. FLASH, Transitional, New York

Graduate Medical Dental Education
Consortium, Buffalo, NY

Graduate Medical Dental Education
Consortium, Buffalo, NY

Universil) of Virginia,
Charlonesville, VA

DAVID J. FIORELLA, lntcmal Medicine

THOMAS F. HUGHES, Family Practice, UB

MARK JAJKOWSKI, Surgery, UB

THOMAS J. GENNOSA, Family Practice,

(Prelim.), UB Graduate Medical
Dental Education Consortium,
Buffalo, NY; and Oplttlralrrwlog_\,
Louisiana tate niYersity Eye
Center, Ne" Orleans, LA

MICHAEL S. LEONARD, Pediatrics, UB

RAJIV K. JAIN, Medicine/Pediatrics,
Duke UniYersity Medical Center,
Durham, NC

TIFFANY B. GENEWICK, Obstetrics (.-.
Gy necoiOg)', UB Graduate Medical
Dental Education Consortium,
Buffalo, Y

GARY J. ELKIN, /ntcnwl Medrcrne,

Health Service, Stanford, CA

Gynecologj, Temple University
Hospital, Philadelphia, PA
Louis University School of Medicine,
St. Louis, MO

(Prelim.), i ter of Charity Hospital,
Buffalo, Y; and Diagnostic
RadiologJ, johns Hopkins Hospnal,
Baltimore, MD

Graduate Medical Dental Education
Consortium, Buffalo, NY

JEAN(. HSIAO-WANG, Obstetrics c~

Yu-LUEN Hsu, lntenwl Medicine, St.

BRIAN J. FORTMAN, /ntcnwl Medicine

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(Prelim.) Madigan Army Medical
Center, Tacoma, WA
WALTER J. KANTOR, Emergency

Medicine, University Health Center,
Pittsburgh, PA
DAVID KAUFMAN, Pathology, Mt. Sinai

Hospital,

m

New Haven Hospital, New Haven, CT

e

ew York,

9

9

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Graduate Medical Dental Education
Consortium, Buffalo, NY
KWOK Ll, lntenwl Medicine (Prelim.),

UB Graduate Medical Dental
Education Consortium. Buffalo, Y;
and Ophthalmology, Louisiana State
University Eye Center, ew Orleans, LA
DOMINIC R. LIPOME, ln!enwl Medicine

(Primary Care), UB Graduate
Medical Dental Education Consortillln, Buffalo, NY
HAROLD I. LITT, lrHemal Medicine

(Prelim.), Mt. Auburn Hospital,
Cambridge, MA; and Diagnostic
Radiology, Hospital of the University
of Pennsylvania, Philadelphia, PA
CHENG H. Lo, Surgery, Stony Brook
Teaching Hospital, Stony Brook, Y
JIADE J. Lu, Internal Medicine (Prelim.),
Sisters of Charity Hospital, Buffalo,
Y; and Radiation Oncolog), jackson
Memorial Hospital, Miami, FL
BETH M. MACDONALD, Family Practice,
Southwest Washington Medical
Center, Bush Prairie, WA
MICHAEL A. MANKA, Emergency

Medich1e, UB Graduate Medical
Dental Education Consortium,
Buffalo, NY
DEBORAH J. MANN, Emergency Medicine,

UB Graduate Medical Dental
Education Consortium, Buffalo, NY
CHRISTOPHER (. MASCIA, Pediatrics,

Medical College of Virginia,
Richmond, VA

�•

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~
I

L. WALK, Family Practice,
Highland Hospital Program,
Rochester, NY

PAULS. MAll, Pcdiatncs, Children's

JOHN P. PATTI, \1rdiclllc/Pediatrics, UB

KARIN A. SELVA,

Graduate Medical Dental Education
Consortium, Buffalo, NY

Pcdtatrics, Uni,·ersity
of ew Mexoco, School of Medocine,
Albuquerque, M

LISA

Hospital of Pholadelphoa, Philadelphia, PA

L. MCNALLY, Surgery (Prelim.),
University of Rochester, Strong
Memorial Hospital, Rochester, NY:
and Urology, niversity of Rochester,
Strong Mcmonal Hospital,
Rochester, N'r

OSCAR E. PIEDAD,

Family PracL!cc,
Richland Memorial Hospital,
Columboa, SC

EDWARD SILVERMAN, Obstctncs &amp;
G_\IICcolog_\, Mamwnodes Medical
Center, Brooklyn, N'r

JAMES G. WAXMONSKY,

FREDERICK J. PIWKO, Fanlll) PnJctice,
\\ olllamsport Hospital and Medocal
Center, Wolliamsport, PA

INDRANI SINHA,

Pedtatrics, Unovers1ty of
Florida, Shands Hospital,
GameS\ille, rL

KEE Y. WEE,

KATHRYN A. MCVICAR, Pcdwtrics,

JONATHAN W. SIRKIN, Psychiatl}, UB

NAOMI D. WEINSTEIN,

f.,Gynecology, Unl\erslt) of Rochester,
Strong Memonal Hospotal,
Rochester, NY

STEVEN R. POSNER, urger\, Unoversit)
of Michigan Hospitals, Ann Arbor,
Ml
JOHNS. PULVINO, Obstetrio &amp;
G) necology, Mmne Medical Center,

KAREN A. SNELL, Obstetrics f.,Gynecology , Ba)'State Medical Center,
Springfield, MA

WILLIAM J. MEDWID,

KAVITHA T. RAM, Obs!Cims

MELANIE

Presbytenan Ho pita!, Ne" York,

Y

THOMAS P. MEAD, Obslrtms

Family Practice,
Beverly Hospital, Danvers, MA

PracL!ce, t.;B
Graduate Medocal Dental Education
Consortium, Buffalo, NY

KIMBERLY E. METZ, Fanuly

DAVID T. MILLER, Surge'} (Prclun.), UB

Graduate Medocal Dental Education
Consortium, Buffalo, Y: and
Orthopedtcs, B Graduate Medocal
Dental Education Consoruum,
Buffalo, Y

Emergency Medicine,
Long Island jew1sh Medical Center,
Long Island, NY

PINAKI MUKHERJI,

DWAYNE A. NARAYAN, Psychiatry,

noverslty of Virgmia, Roanoke,\ A

Obstru 1c; f_,Gynecology, noverslty of Texas
Southwestern Medocal School,
Dallas, TX
EMMEKUNLA K. NYLANDER,

NAYOMI E. OMURA, Internal Medicine

(Prclun.), George Washmgton
University, Washmgton, DC

J. 0STEMPOWSKI, Orthopedics,
Universit)' of Cincinnati Hospital,
Cincinnati, OH

MICHAEL

CHRISTOPHER PACE, Urology, Unoversit)
of Texas Southwestern Medical
School, Dallas, TX

Emngency Medtchtc,
UB Graduate Med1cal Dental
Education onsortlum, Buffalo, 'r

PARAS PANDYA,

Medtwoc,
Unoversoty of Connecticut,
Farmington, CT

NEIL N. PATEl. Internal

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C"
G\IICcolog_v, LB Graduate Medocal
Dental Education Consortium,
Buffalo, Y

SUNG Y. SoN, Fwmlv

TranstL!ollal, Evanston
Hospital, Ch1cago, IL

Graduate Medical Dental Education
Consortium, Buffalo, Y

J. RIEGEL, llllernal \trdicine, St.
Elizabeth's Medical Center, Boston,
MA

KRISTIN A. STIEVATER, Psychiatt) , UB

Fwnily Practice,
UB Graduate Medocal Dental
Education Consortium, Buffalo, N'r

MICHAEL(. STONER,

H. WILLIS, JR., i\eurosurgery,
CleYeland Clinic Foundation,
Cleveland, OH

BYRON

MARY M. WILSCH, Obstetrics &amp;
Gynecology, University of Rochester,
Strong Memorial Hospital,
Rochester, Y

Graduate Medical Dental Education
Consortium, Buffalo, NY

KRISTEN M. ROBILLARD,

ARLENE S. ROGACHEFSKY, Dw11a!Oiogy.

Cle,·eland Clinic Foundation,
Cleveland, OH

JOSEPH(. WITIMANN, Pediatrics, UB

Surgcty, Medical
College of VIrginta, Richmond, VA

Graduate Medical Dental Education
Consoruum, Buffalo, Y

Obstcutcs &amp;
G\nrcology, Albany Medical Center
Hospital, Albany, NY

TOVA R. STRAM,

l. WRAZEN, Pedialt ICS, Oregon
Health Sciences ni\-ersity, Portland,
OR

JENNIFER

Medicine!
Pechatms, Baystate Medical Center,
pnngfield, MA

SUSAN M. SZIMONISZ,

Practice, LB
Graduate \ted1cal Dental Education
Consortium, Buffalo, Y

MARY A. RYKERT, Fanul_1

Practice,
Niagara Falls Memorial Hospital,
Ntagara Falls, Y

CHARLES YATES, FamilJ

Pedtautcs, B
Graduate Medical Dental Education
Consortium, Buffalo, Y

MAXINE E. SZUMIGALA,

STARLEEN (. SCHAFFER, \lcdicine/

Pediatncs, Jackson Memonal
Hosp1tal, Moamo, FL

MARK R. ZAMBRON, Medicinc/Pediallics,

UB Graduate Medical Dental
Education Consortium, Buffalo, NY

Emergency Mcdicme,
UB Graduate Medical Dental
Educauon Consortium, Buffalo, )

RENATE TREADWAY,

DAVID F. SCHMITZ, Fcuml) Practice,

Famoly Practice ResidenC) of Boise,
Boise, ID

Fanuly Practice,
Niagara Falls Memonal Hospital,
iagara Falls, Y

DANIEL W. ZORICH,

Obs!CIIics f.,
Gynecology, UB Graduate Medical
Dental Education Consortium,
Buffalo, NY
MILLICENT H. TREVETT,

J. SCHROT, Surget) (Prelim.),
t. Louis niverslty chool of
Medicine, St. Louis, MO

RUDOLPH

J. SCHUECKLER, Orthopedics,
McGaw Medical Center, orthwestern Uni,·ersity, Chicago, IL

JON UDWADIA,

Pccliatr tcs, UB
Graduate Med1cal Dental Education
Consortium, Buffalo, N)

EROL VEZNEDAROGLU, Surgcl) (Prelun .),
Thomas jefferson UmverSll),
Philadelphia, PA: and 1\eurosurget) ,
Thoma jefferson UmverS!l),
Philadelphia, PA

DOUGLAS A. SCHULTZ,

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Pediatrics, UB Graduate
Medical Dental Education
Consortium, Buffalo, NY

OTTO

0

lntetnal Medicine
(Prelim.), St. Mary's Medical Center,
Long Beach, CA: and Radiation
Oncology, Stanford University
Hospital, tanford, CA

Scan S. WILLIAMS,

PATRICK J. STEIN, Psychiatl), UB

BRIAN

f

Pediatrics,
University of South Florida, College
of Medicme, Tampa, FL

Ptactice,
Lancaster General Hospnal,
Lancaster, PA

EILEEN B. REILLY,

u

Dtagnostic Radiolog_\,
Uni\·ersll\ Hospitals of Cleveland,
Cleveland, OH

Graduate Medocal Dental Education
Consortmm, Buffalo, NY

Portland, ME

B

Psychiall), UB
Graduate Medical Dental Education
Consortium, Buffalo, NY

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New UB Chair honors professor
HE U IVERSITY HAS HONORED
a respected faculty member, Eugene R. Mindell, M.D., with the
establishment of the Eugene R.
Mindell M.D. Chair in orthopedic
surgery.
Mindell, UB professor emeritus and
chair of the department of orthopedics
from 1964 to 1988, conducts research in
orthopedic oncology and bone pathology.

Eugene Mindell
He is particularly interested in new
treatments that avoid total amputation.
For example, Mindell takes pride in
saving the arm of a 19-year-old woman
with osteogenic sarcoma just above her

wrist. After the cancer was removed,
along with part of the radius, the
patient's bone was reconstructed with
bone from a bank. Ten years later, the
patient has a good arm with an excellent grip, and no recurrence of disease.
After interning at the Cincinnati
General Hospital, Mindel! was stationed as a naval officer at the Veteran's
Hospital in Columbia, SC. He completed his residency at
the University of Chicago Clinics.
Mindell met his wife
of 50 years, june A.
Mindell, while he was
a medical student and
she was an undergraduate at the University of Chicago.
They have four children and three grandchildren.
Robert Gillespie,
M.D., chair of UB's
Department of Orthopedic Surgery, said of Mindell: "He is
a man of great charm and obvious
integrity and leadership qualities. His
greatest accomplishments are his dedication to the residency program and

his work as a teacher. He is a true
academic surgeon."
The chair is funded by a charitable
remainder trust commitment from Byron
A. Genner III, M.D., UB class of 1954.
Further gifts toward the chair are being
sought.
Genner's gift places $825,000 in real
estate in trust for the medical school,
while still generating income for Genner
during his lifetime. The school will seek
more money to bring the total funding
for the chair to between $1 million and
$1.5 million.
"UB provided me with an outstanding undergraduate and medical education," said Genner. "This became evident during my internship and orthopedic surgery residency. It was satisfying
being as well or better prepared than my
peers in my academic endeavors."
Genner spent 15 years on active duty
in the U.S. Air Force, retiring as a lieutenant colonel. His career includes posts
as associate clinical professor at George
Washington University and assistant
clinical professor at Georgetown University. He continues a part-time orthopedics practice, along with an active
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medical-legal consulting service.
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As part of UB's sesquicentennial celebration, these plaques were installed in downtown Buffalo to commemorate the first three homes of the medical school.

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Physician

Summer

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�Robert N. Spengler, Ph.D.
Neuroimmunologist
WORKING AT THE INTERSECTION OF
IMMUNOLOGY AND NEUROBIOLOGY
IT' 5

o sEcRET

that the mind has a profound effect on

healing. Quantifying that relationship and examining it at
the molecular level is the work of Robert

Q)

sity of Michigan, where he also did
postdoctoral work in pathology.
He joined UB as an assistant professor of pathology in 1989.
His primary area of interest is
cytokines, a class of immune system hom10nes that serve as cellto-cell communication signals.
Once thought to be active only in
the immune system, cytokines
have been found to have many
functions in the nervous system,
as well. This has led researchers to
believe that cytokines participate

"We're looking for a better understanding of how the brain controls body functions , and the other
way around-how cells associated with the immune system control neuronal functions," says
Spengler, assistant professor of
pathology. "Each system is interdependent on the other. "
Spengler, 4l,isparticularlywell
qualified to explore the fruitful
intersection of immunology and
_Eeurobiology. He earned his Ph.D.
in pharmacology from the Univer-

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Physician

in neuro-immune communication
and may even act as neurotransmitters in certain situations.
Spengler is particularly interested in tumor necrosis factor.
Like many other cytokines, it was
first identified and named for its
connection with an immune function (killing tumor cells). ow
researchers believe it also has neurologic functions. Because the concentration of tumor necrosis factor often governs how it functions
in different disease states, much
of Spengler's work focuses on investigating how the body regulates the release of the substance.
Another of Spengler's research
areas is psychotropic drugs. He
has investigated the biochemical
activity of antidepressant drugs
and how cytokines may be linked
to depression. He also studies the
use of antidepressant drugs to
alleviate neurological pain, which
occurs when a disorder such as
arthritis causes chronic pain that
creates a continuous circuit in
the brain, causing the sensation
of pain even without any further
stimulus from the site of the disorder. Drugs that affect neural
behavior may do so by regulating
cytokine expression or sensitivity, according to Spengler.
"We use drugs as a tool to
understand a disease, " he explains. "Drugs are used because
they work, not because we know
how they work."
Spengler is also beginning experiments on a second group of
cytokines, the interleukins,
which seem to perform many of
the same functions as tumor necrosis factor. This redundancy,
he theorizes, shows how important these functions are.
"It's clearly the body's way of
backing itself up," he says. +

Summer

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Two D~tinguished Professors named
wo members of UB's medical fac- a department-wide commitment to upulty have been named to the rank holding the policy. It is largely through
of Distinguished Professor, the his work that UB has been recognized
highest rank in the State University as a national leader in recruiting and
of ew York system, by the SU Y
retaining students and facBoard of Trustees.
ulty from traditionally
James P. olan, M.D. , was named
underrepresented groups.
Distinguished Service Professor, awarded
olan has been a memin recognition of extraordinary service to
ber of the Governor's
the community, state, or nation.
Council on Graduate
Perry Hogan, Ph.D., was named Perry Hogan
Medical Education, and
Distinguished Teaching Professor , has served as president of the ew York
an equivalent honor that recognizes State chapter of the American College of
outstanding teaching competence.
Physicians.
olan, who recently stepped down
Hogan teaches cardiovascular physiafter 16 years as chairman of the Depart- ology, cell membrane phenomena, and
ment of Medicine, is an internationally the electrophysiology of excitable cells.
recognized expert in For many years he has taught cardiac
liver function, liver and circulatory physiology to first-year
disease and injury, medical and graduate students.
and endotoxins.
Hogan received the Louis A. and Ruth
His efforts in the Siegel Award for Outstanding I eacher in
1970s led to a the Preclinical Sciences five times during
full and fair affirma- a 16-year period. The award is given by
tive action policy and medical students and fellow faculty. +
James Nolan

I

UB microbiology
professor dies at 76
ugene A. Gorzynski, Ph .D. '68,
of Homburg, NY, a professor of microbiology and pathology at UB and chief of
the microbiology section at the Buffalo
VA Medical Center, died May 16 after a
lengthy battle with cancer. He was 76.
In 19 55, Gorzynski and the late Erwin
Neier, an internationally known bacteriologist, were the first to describe enteropathogenic f. coli bacteria as a toxin producer that
could cause severe diarrhea in infants and
young children.
Aveteran of World War II, Gorzynski served
as director of bacteriology with the Army General Hospital in England. While there, he met
his future wife, Ruth Repp, an Army nurse and
Missouri native. She died in 1992.
At different times, Gorzynski worked at the

VA, Children's Hospital, and Roswell Pork Cancer

Nielsen and Nolan Win Alumni Association Awards

Institute, and served as an assistant director oft he

ancy H. ielsen, M.D., a 1976 and serves as regional medical director
graduate of the medical school for the Board of Professional Medical
and a former member of the SU Y Conduct in the ew York State DepartBoard of Trustees, has been given ment of Health.
A specialist in internal medicine
the Samuel P. Capen Award , the
and infectious disUB Alumni Association's most
ease, she is a clinical
prestigious award.
assistant
professor of
The award recognizes alumni who
medicine
at UB.
have made "notable and meritorious
The
Alumni
Ascontributions to the university and its
sociation also gave
family ... influencing growth and imthe Walter P. Cooke
provement of UB and stimulating othAward to James P.
ers to give their active interest and
olan , M.D. The
material support to the university. "
honor recognizes
ielsen was the first woman to be
exceptional service
elected president ofThe Buffalo General
to UB by a nonHospital medical staff. She is past presialumnus .
+
dent of the Erie County Medical Society Nancy Nielsen

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Erie County Health Department. He hod taught at
the UB School of Nursing and Erie Community
College as well as at the UBmedical school.
Amember of the UB-based Ernest Witebsky
Center for Immunology, he served on the admissions committee of the School of Medicine and
Biomedical Sciences. An amateur violinist,
Gorzynski performed with the Amherst and Orchard Park Symphony orchestras for more than
30 years. He also was commanding officer of the
365th General Hospital for the U.S. Army Reserves in Amherst from 1966-69. He retired as a
colonel in 1979.

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"I had never known
so much about someone "
•••

BY CHR I S SCHAEFFER , UB MEDICAL SCHOO L C LASS OF 1998

n the summer of 1995, after my first
year of medical school, I spent six
weeks at The Buffalo General
Hospital's Outpatient Clinic.
The story of that externship is
the story of the 100 people I saw. I
was fascinated by their stories, by their
problems, by the factthatl was sitting in
the room with them, wearing a white
coat and writing it all down. Of all the
stories that I came across that summer,
one will always stay with me.
Mr. R was a 54-year-old man, divorced, with one son. His face had the
look of worn shoe leather. He was gaunt,
with uncut white hair and skinny legs
inside cowboy boots.
In our first interview, during a checkup, Mr. R gave me the gist of his complaints. But what fascinated me was that
his life had been so different from mine.
He was poor, he had grown up without
any of my advantages, and he had taken
pleasure where he could find it.
Later, my preceptor, Dr. Richard
Schifeling, explained alcoholic cirrhosis and the attendant problems Mr. R
was having-ascites and hemorrhoids,
to name two. Mr. R returned the next
week, before his scheduled appointment,
complaining of pain and worsening ascites. I waved to him in the hall, oddly
glad to see a familiar face in the crowd.
ext week Mr. R was back. This time
I asked to see him. In the sea of everchanging, ever-similar complaints, Mr.
R seemed like a rock of certainty- !
already knew what was wrong with him.
I talked to Mr. R about his belly and
how things were going at home. Frankly,
I was curious about how his life had

come to this point. He could barely
move himself around the examining
room. I wanted to know, 'Who is this
person who has done this to himself?'
I put all of my empathy and listening
skills to work, and for my efforts learned
only that he lived with "a woman friend"
and had just decided to give up drinking. Mr. R asked me to take off his boots
becau e it hurt too much to bend over.
That day, Dr. Schifeling recommended a transjugular intrahepatic
ponosys-temic shunt, or TIPS, to bypass his failing liver.
Mr. R looked at us, then looked away,
and consented by saying, "Whatever you
got to do.l just want to get this over with."
When Mr. R was admitted, I thought,
"Hah! He'll be here all the time-now
he'll have to talk to me. " My increasing
familiarity with his medical condition
made my complete lack of understanding of him bother me more and more.
When I visited, we chatted about nothing-the nurses, the food, the TVs remote
control. What I really wanted to know was
if he was nervous about the surgery, if he
really had kept drinking even with his liver
destroyed. I left without answers.
Mr. R went from poor to worse. His
kidneys began to fail , so he couldn't

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have the surgery after all.
Over the next two weeks I saw a
myriad of people in the outpatient clinic,
but every morning and evening I visited
Mr. R. We tried everything we could to
help, including multiple abdominal taps
to relieve his ascites. One memorable day
I stood with an attending, a resident, an
intern, and a fourth-year student as the
intern began an abdominal tap.
After the initial excitement, everyone left except the intern and myself.
The intern looked at me, considered his
aching arms, and asked ifl would like to
finish the tap. The next thing I knew,
the intern had left, I was holding a
needle somewhere inside Mr. R's belly,
and Mr. R was talking on the telephone.
All I could think was, "What is going
on?? I hope nothing goes wrong! "
Every day he was in the hospital, I
saw his complete medical report, from
his blood and urine to how he had slept
the night before. I had never known so
much about someone.
In the final weeks of my externship it
became clear to me (long after it had
become clear to everyone else) that Mr. R
was going to die, and die soon. Whenever
I saw him, I waited quietly so he could
bring up anything he wanted to talk
about. I asked how he felt, I joked with
him. Nothing changed. He still complained about his roommate, his girlfriend, his son.
I never got to know Mr. Rduring our talks.
He stayed private and separate from me.
Knowing his prognosis, Mr. R decided to go home. He tried to cheer our
blank faces by joking that he'd come to
the clinic, "just like before."
He left on Friday. When I got to work
on Monday, Dr. Schifeling took me aside
and told me that Mr. R had died over the
weekend.
+
Chr-is Schaeffer, l-..ho will enrcr h1s !hird year a! L'B School of
\.fed1cme and Biomedical Sciences 1h1s fall, is the secretan- of tht'
\.1edical Studen! Polit\

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�1996 reunion portraits
en classes were honored at this year's Reunion Weekend
festivities as they gathered in Buffalo to remember old times
and renew acquaintances.

FIRST ROW:john Crissey, Raymond Trudnowski, Stanley Cyran,
William Walsh, Myron Williams, john Allen, Annabel Irons,
Edward Gudgel, Donato Carbone.
SECOND ROW:Lawrence Golden, William Marsh, orman om of,
Harry Petzing, Fred Schwarz, Charles Bauer, Harold Levy,
Herbert Pirson, Ross Imburgia, Thomas Morgan, R. joseph
aples, Maynard Mires, Albert Rowe, Eugene Marks.
THIRD ROW: Raymond Osgood, Richard Munschauer, Bernard
Groh, Carllmpellitier, Willis Allen, Guy Hartman, Charles
joy, W. William Tornow, Amo Piccoli, Frederick Musser.

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FIRST ROW: Lester Wolcott, August Bruno, Donald Pinkel,
Leonard Danzig.
SECOND ROW: Alvin Volkman, james LoVerde, Allen Goldfarb,
Milton Robinson, Eugene Leslie, Marvin Pleskow, Eugene
Teich, Carl Conrad, Edward Shanbrom, Harold Krueger.

Reunion Classes Continued on page 30

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FIRST ROW: Peter Goergen, Bernard Sklar, Helene Buerger, Sue
McCutcheon,john Bartels, Robert Reisman, Fred Lee, Herman
Schoene.
SECOND ROW:john Hodson, joseph Kunz, Fred uessle, Robert
Corretore, Paul Ronca, john Walters, Hugh 0' eill, Carl
Schueler, jean Haar.
THIRD ROW:Edmond Gicewicz, Mark Dentinger, Fred GoldsteinGretan, Erick Reeber, Dennis Heimback, George Christ.

FIRST ROW: Eugene Cimino, Harold Brody, Michael Cohen,
james Markello.
SECOND ROW:joel Bernstein, William Hewett, A. Thomas Pulvino,
Thomas Ciesla, Washington Burns Ill, Sylvia Kennedy, ].
Anthony Brown, Wende Young, Henry Goller, Edwin Manning,Jonathan Logan,joseph Fermaglich, Howard Wilinsky.

FIRST ROW: Edwin jenis, Murray Yost, Robert Barone, jared
Barlow, Cary Presant.
SECOND ROW: Roger Seibel, jeffrey Kahler, Virginia Rubinstein,
David Buchin, Rudolph Oehm, Ross Guarino , William
Sperling, Frank Barbarossa, james Cuffe.
THIRD ROW:Harold Grunert, David Wallack, Eugene Spiritus, H.
john Rubinstein, Michael Weintraub, Louis Antonucci, Thomas Bradley, Wayne Fricke, Marcella Fierro, james Moran,
john LaDuca.

FIRST ROW: Colleen Livingston, Annie Terry English.
SECOND ROW: Marvin Stein, Askold Mosijczuk, Dennis adler,
Scott Kirsch, David Rowland, David Bloom, Sigmund Gould,
Roy Oswaks, Allen Berliner, Robert Kaufman, Richard Manch,
joel Paull.
THIRD ROW:jay Harolds, Donald Marcus, David Hoffman, Martin Mango.
FOURTH ROW:Manny Christakos,] ames McCoy,] ohnAntkowiak.
FIFTH ROW: Charles Yeagle.

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�FIRST ROW: Gregg Broffman, Arnold Wax, Linda Wild, Susan
Barde, Robin Lazar-Miller, Patrick Hayes, Karen Glasgow,
Louise Isenberg-Dallaire, Stephan Levitt, Hartwig Boepple,
Paul Schwach.
SECOND ROW: Martin Barron, Grant Golden, Daniel Wild, Jon
Yerby, Christopher Barde, Melvin Pohl.
THIRD ROW: David Myers, Christopher Brandy, William Bishop,
Dennis Pyszczynski, John Bodkin.

FIRST ROW: Suzanne Bradley, Beth Heitzman Donahue, Betty
Wells.
SECOND ROW:George Bancroft, ToddJacobson, Pablo Rodriguez,
Stanley Bukowski, Daniel Castellani, Pano Yeracaris.

FIRST ROW (KNEELING AND SITTING): Carmen Todoro, Katrina Guest,
Donnica Moore, Sanford Levy, Molly 0'6-orman, Paul
Holmwood, Deborah Puckhaber, Mary Bennett.
SECOND ROW: Megan Farrell, Shirley Anain, William Beneke,
Andrew Giacobbe, Edward Stulik, Lance Besner, Riyaz
Hassanali, Leonard Portocarrero, Karin Choy, Sean O'Brien,
Mark Vickers, Deborah Richter.

FIRST ROW: Alison Koehler, Kathylynn Southard, Susan Littler,
Grace Alessi, Mary Bonafede, Rosalind Nolan Sulaiman, Elissa
Bookner.
SECOND ROW: Kinga Tibold, Joseph Barrocas, Joseph Bonafede,
Steven Abbey, Richard Alessi, Jennifer Ferraro.

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�Treating children from around the world
LYNNETTE NIEMAN , '78, CLINICAL DIRECTOR OF THE NATIONAL INSTITUTE OF
CHILD HEALTH AND HUMAN DEVELOPMENT

ynnette Kaye Nieman, M.D., values the knowledge and practical experience she carried
from UB to her career at the National Institutes of Health (NIH). However, one thing she
hasn't found a use for was an adage she was taught here: in medicine, if you hear hooves,
it's more likely a horse than a zebra.
"Around here, that just isn't true: hooves mean it's probably a zebra," explained ieman,
43, clinical director of the

ational Institute of Child Health and Human Development, one of

16 component institutes at NIH. Nieman encounters the exotic and uncommon every day as
she studies and treats afflicted children who come from throughout the world to the Institute's
Bethesda, MD, clinic for treatment of rare endocrinological disorders. "Simply put,"

ieman

explained, "we get to see weird things from all over the world."
ieman oversee patient care, protocols, credentialing
and medical education at the Institute , administering a 36bed inpatient unit and large outpatient clinic. More than
70 physicians, from fellows and trainees to experienced,
board-certified experts , provide direct care through affiliation with the Institute. Young doctors who complete
fellowships at the Institute are frequently recruited into
academic medicine, the pharmaceutical industry or regulatory posts, including the Food and Drug Administration,

A Buffalo native, ieman is board-certified in endocrinology and internal medicine. She obtained her undergraduate degree in molecular and cellular biology at Smith
College and attended UB School of Medicine and Biomedical Sciences between 1974-78. She performed her residency in Buffalo as well , rotating between Buffalo General,
the VA hospital, and what is now ECMC. She rose to chief
resident during her third residency year. ieman served as
an endocrine fellow in Buffalo for a year before joining IH

explains ieman.
Although the federal government has tightened its belt
in recent years, ieman says that IH still enjoys relatively
stable funding. Independence from constant grant-garnering enables IH clinicians and researchers to pursue "more
high-risk research where there might not be a clear-cut
payoff," explains ieman . Some of the work the Institute
does in vaccine development is "really cutting edge," she
added. Field trials take place all over the world , including
current projects in Vietnam, Egypt and Israel.

in 1982.
ieman has authored more than 100 major journal
articles and book chapters, most on Cushing's Syndrome
or female reproductive anatomy.
Cushing's Syndrome is a rather uncommon disease
which ieman has researched , written about , and spoken
on extensively. A natural overproduction of cortisone by
the adrenal system, Cushing's comes in varying degrees of
severity. Although relatively treatable, early Cushing's
symptoms can be difficult to distinguish from more com-

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�Cushing's. In addition,
she has examined other
potential uses for the
drug, which the FDA is
now examining. "The
drug seems to have potential for reducing fibroids and stalling endometriosis ," she explained. Thirty million
women a year experience these problems,
which are the most
common reasons for
hysterectomies, according to ieman.
Dr. "Pepper" Davis,
ieman's first attending physician in Buffalo, deserves credit for
steering
her
toward
endocrinology,
she recalled. "I was
mon ailments, ieman explains.
"The early signs, such as weight gain, hypertension and interested in gynecology, but we talked a lot and he
mood swings, are frequent even among the general popula- introduced me to the idea of medical endocrinology."
ieman also credits UB medical school for showing
tion," she said, "so we do a lot of work teaching clinicians how
her how to examine philosophical and bio-ethical conto distinguish Cushing's from more common ailments."
siderations during her training, tools
Later stages of Cushing's, however, are
which
she has now revisited in dealing
unmistakable. Patients will develop round,
11
with the RU 486 research.
Simply put1 we
reddened faces and weight gain in the center
ieman, her husband and their two
of the body, with purple stretch marks around
children live in Bethesda. After years
the midsection. Fully developed Cushing's
get
to
see
weird
dedicated
to the study of endocrinologican be fatal. Generally, victims succumb to
cal change , ieman is occasionally
ancillary problems including hypertension,
tempted to "treat" her 13-year-old son
infection, or adrenal cancer.
things from all
for
puberty. "His mouth definitely went
ieman's research into Cushing's has
into puberty before the rest of him," says
brought unique opportunities to study potenNieman. "There are those days, when I
tial uses for RU 486, the controversial drug
over the world."
tell my husband , 'You know, I could
used in other countries as an "abortion pill."
cure this!"'
ieman has found that RU 486 is an
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STEVE

COX

�SURF
THE
NET!

Three generations of UB doctors
he University at Buffalo's sesquicentennial celebration serves as a special milestone for the Levy family.
It will mark the 50th anniversary of the graduation from B of
Harold]. Levy, M.D., and the lOth
anniversary of the graduation of his son,
Sanford H. Levy, M.D. It will also be the
Slst anniversary of the graduation of
Harold's father, Sidney H. Levy, M.D., a
radiologist who started the Levy line of
UB physicians.
Sidney, who died in 1945, received
his M.D. in 1915 from the then-private
nivcrsity of Buffalo, interned at the old
Eric County Hospital, and then served as
aU .. Army medical officcrduringWorld
War 1. When idncy opened his practice
in diagnostic radiology, he was only the
second physician to render such services
in post-World War I Buffalo.
"When he started his practice, some
hospital did not have radiologic equipment, o the patients were brought to my
father's office in ambulances for such ser-

vices," said Harold, a Buffalo psychiatrist.
Harold graduated with honors from
the UB medical school in 1946 at the
young age of 21, and served for a short
time in the U.S. Army Medical Corps. ln
1948, Harold was recalled to active duty
and served as chief of psychiatry at army
hospitals in Korea and Hawaii. Later,
Harold entered the growing field of psychosomatic medicine.
ow, at age 71, Harold, a life fellow
of the American Psychiatric Association, continues his private practice at
Psychiatric Associates of Western ew
York and serves as a clinical associate
professor at UB.
Exactly 40 years after Harold received
his medical degree, he watched his son,
anford, graduate with highest honors.
'Tve wanted to be a doctor for as long
as I can remember," recalled Sanford, an
internist at Sisters Amherst Health Center. "Seeing my father working in medicine and the strong relationship he had
with patient had a positive influence
on me. Even today, my father continues
to teach me."
A fellow in the American College of
Physicians, an ford is also an authority on
alternative and complementary medicine.
Following his father's lead, Sanford also
teaches and mentors UB medical students
and residents at Sisters Hospital.
Harold is a member of the james Platt
White ociety, a past president of the
Medical Alumni Association , and reunion co-chair for the class of 1946.
"I have an extreme sense of pride both
as an alumnus ofUB and as a physician,"
he said. "Medicine is the highest calling
and i one of the most commendable
professions to enter. There is no greater
sense of satisfaction and gratification than
to serve your fellow man and improve his
+
quality of life. "

The Levys

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�........ . ..

Reunion classes support UB
his year's reunion classes made generous
donations to the medical school during
the annual Spring Clinical Day and Reunion Weekend festivities.
In all, $130,030 was pledged to the
medical school to be used for scholarships for worthy students. Following is a list of
participating class members and class totals.
Dr. Thomas]. Murphy
Dr. Edward A. Penn

CLASS OF 1946-$58,900
Dr. john G. Allen
Dr. Charles D. Bauer
Dr. Robert A. Brown

Dr. Donald P. Pinkel
Dr. Marvin j. Plcskow

Dr. john T. Crissey

Dr. Robert E. Ploss

Dr. Stanley j. Cyran , Jr.

Dr. Milton Robinson

Dr. Maier M. Driver
Dr. Lawrence H. Golden

Dr. Gerard E. Schultz
Dr. Edward Shanbrom

Dr. Bernard F. Groh
Dr. Edward F. Gudgel

Dr. Eugene M. Teich
Dr. Alvin Volkman

Dr. Guy L. Hartman

Dr. Lester E. Wolcott

Dr. Charles A. joy

CLASS OF 1956-$3,050

Dr. Elliott C. Lasser

Dr. M. David Ben-Asher

Dr. Harold J . Le,·y

Dr. Robert B. Corretore

Dr. Eugene M. Marks

Dr. Joseph j. Darlak
Dr. Dennis P. Heimback

Dr. William L. Marsh

Dr. Arthur T. Skarin

Dr. Lawrence D. Lubow
Dr. Donald H. Marcus
Dr. Merrill L. Miller

Dr. Elizabeth Donahue
Dr. Paul D. Fadale
Dr. jonathan Gewirtz

Dr. Wende W . Young

Dr. Richard L. Munk

Dr. joanne G. Gutliph

Dr. Denms A. Nadler

Dr. LyndaM. KarigHohmann
Dr. Todd A. jacobson

CLASS OF 1966-$13,825

Dr. Paul M. Ness

Dr. Louis]. Antonucci

Dr. joel H. Paull

Dr. Robert E. Kaplan

Dr. Frank j. Barbarossa

Dr. Dadd W. Potts

Dr. Girard E. Robinson

Dr. jared C. Barlow

Dr. Douglas S. Richardson

Dr. Daniel P. Schaefer

Dr. Robert M. Barone

Dr. Da,·id M. Rowland

Dr. Anne Shain

Dr. Thomas \V. Bradley

Dr. Richard I. Staiman

Dr. Evan B. Shap1ro

Dr. james j. Cuffe . Jr.

Dr. William C. Sternfeld

Dr. Ross A. Sih erstein

Dr. james D. Felsen
Dr. Melvin f'ox

Dr. Annie Terry-English

Dr. Da,·id Small

Dr. Harold Trief

Dr. Lloyd D. Stahl

Dr. Harold F. Grunert . Jr.
Dr. Edwin H. jenis

Dr. Francis j. Twarog

Dr. Roberta C. Szczurek

Dr. Stephen . . Vogel

Dr. David M. Thomas

Dr. jeffrey L. Kahler

Dr. Bennett G. Zier

Dr. Frederick L. Williams
Dr. Georgianne ZigarowiCz

Dr. KcnnethV. Klementowski

CLASS OF 1976-$6,300
Dr. ~tichael L. Aaron
Dr. Serafin C. Anderson

CLASS OF 1986-$4,920
Dr. Laurel A. Bauer
Dr. William j. Beneke

Dr. Donald M. Pachuta
Dr. Cary A. Presant

Dr.
Dr.
Dr.
Dr.

Dr. Ben W. Rappole
Dr. james F. Shaffer

Dr. Michael R. Bye
Dr. Anthony Camilli

Dr. William L. Sperling
Dr. John E. Spoor
Dr. David Wallack
Dr. Michael !. Weintraub

Dr. Paul B. Cotter. Jr.
Dr. David A. Della Porta
Dr. Geraldme K. Kelley
Dr. james Kern

Dr. Sean T. O'Bnen

Dr.
Dr.
Dr.
Dr.

R1chard j. Lederman
Charles H. Michalko
james]. Moran
john j. O'Connor

Dr. joseph L. Kunz

Dr. Maynard H. Mires, Jr.
Dr. Thomas W. Morgan

•

Dr. Paul Stanger
Dr. Ronald H. Usiak, Sr.

Dr. Martin E. Leber

Dr. Annabel M. Irons

- ~

Deborah Beller
Marlene Bluestein
Christopher f' . Brandy
Soma Y. Burgher

Dr. Michele]. Armenia

Dr. Mary K. Bennett
Dr. john H. Bloor
Dr. Marsha E. Brooks
Dr. Lucy A. Campbell
Dr. Timothy E. Frey
Dr. Katrina A. Guest
Dr. Camille Hemlock
Dr. Thomas]. Kufel
Dr. Sanford H. Le,·y

CLASS OF 1971-$17,225

Dr. Richard W . Munschauer

Dr. Fred Lee
Dr. Sue A. McCutcheon

Dr. jennifer S. Kriegler
Dr. john Y. Lambert Ill

Dr. Micha Abeles

Dr. Stephan M. Ledtt

Dr. janice j. Pegels

Dr. R. joseph Naples

Dr. Frederick C.

Dr. john M. Antkowiak

Dr. Nancy H. Nielsen

Dr. Roslyn R. Romanowski

Dr. Norman Nomof

Dr. Jordon S. Popper

Dr. Michael B. Baron

Dr. Christine Privitera

Dr. Mark E. Schweitzer

Dr. Raymond W . Osgood

Dr. Paul D. Barry

Dr. Denms R. Pyszczynski

Dr. Rita R. Sloan

Dr. Harry Petzing

Dr. Paul C. Ronca
Dr. Herman R. Schoene

Dr. Allen I. Berliner

Dr. Thomas L. Ritter

Dr. joy D. Steinfeld

Dr. Amo j. Piccoli

Dr. Matthew W. Szawlowski

Dr. David A. Bloom

Dr. Paul Schwach

Dr. William H. Stephan

uessle

Dr. Herbert S. Pi rson

Dr. jerald A. Bovino

Dr. Carole Shear

Dr. Edward j. Stulik

Dr. Alben G. Rowe

CLASS OF 1961-$9,250

Dr. Barry G. Brotman

Dr. \Varren Thau

Dr. Carmen M. Todoro

Dr. Fred S. Schwarz

Dr. Richard H. Baker

Dr. Kenneth A. Burling

Dr. George Toufexis

Dr. Michael \V . Wood

Dr. W. William Tornow

Dr. Nicholas j. Capuana

Dr. Bernard M. Wagman

Dr. Richard j. Valone

Dr. Harold Brody
Dr. Washington Burns Ill

Dr. Kenneth j. Clark , Jr.

Dr. Arnold Wax

Dr. William P. Walsh

Dr. Michael E. Cohen

Dr. Manny E. Cristakos

Dr. Linda Wild

Dr. Myron E. Williams. Jr.

Dr. H. Howard Goldstein

Dr. Arthur C. Cronen

Dr. Herbert S. Wolfe

Dr. Henry F. Goller

Dr. Lawrence]. DeAngelis

CLASS OF 1981-$5,915

Dr. Paul L. Nadler

Dr. Thomas G. DiSessa

Dr. George Bancroft

Dr. Anthony T.

CLASS OF 1951-$9,645

Dr. William j. Hewett
Dr. Howard M. Hochberg

Dr. Pasquale D. Baratta

Dr. Michael D. Plager

CLASS OF 1991-$1,000
Dr. jennifer f. Hen kind Ferraro
Dr. Colleen A. Mattimore
g

Dr. Carl R. Conrad
Dr. Leonard S. Danzig

Dr. Sylvia R. Kennedy

Dr. Sigmund S. Gould
Dr. Harvey Greenberg

Dr. Andrea C. Bracikowski

Dr. Philip j. Rados

Dr. Seymour j. Liberman

Dr. jay A. Harolds

Dr. Suzanne F. Bradley

Dr. Barry D. Shaktman

Dr. Allen L. Goldfarb

Dr. jonathan Logan

Dr. Barbara I. Karpel

Dr. james B. Bronk

Dr. Mitchell K. Spinnell

Dr. Mark E. Heerdt

Dr. Edwin j. Manning

Dr. Robert B. Kaufman

Dr. Stanley L. Bukowski

Dr. Harold P. Krueger

Dr. Dave B. Olim

Dr. Scott D. Kirsch

Dr. Daniel A. Castellani

Dr. Eugene V. Leslie

Dr. Saar A. Porrath

Dr. Stanley B. Lewin

Dr. James j. Czymy

Dr. james V. LoVerde

Dr. A. Thomas Pulvino

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Why c~tay home for

lEI

the holiiJayc~ ?

Medical Alumni Awards
The front-wheel urive Infinitt-® I 50"'
An interuw more .•paciow thana Rolf,, RL&gt;yce
Silm· Spur 11/. An e:&gt;:ceptionally .fJetzerOild IL:•t
of dtanJarJ lu.."l.·wy feat/ire.•. A 190-hp V6
capah!e ofout-acceleratin.lJ many lll.Ylli:J V&amp;•.
tlnd of cour.•e, the ,ltandarJ-,,etting
pet:formance anJ .•erl'ice of lnfiniti.

The Medical School Alumni Association presented three Lifetime
Career Achievement Awards at
Spring Clinical Day on May ll. The
awards are given to alumni/alumnae in honor of lifelong achievements in important areas of medical

Like e&lt;'ery lnfiniti, llu G20 come.• ll'ith an
e;t:/en,lil'e liA of .•tanJard !u.-wry feature,•; tl
-1-year/ 60,000 mile Ba.•ic Nell' Vehicle
Wtzrranty; 2-1-hour RoaJ.Jitle tl.•.•t:ttance
Program Trip interruption Benefit.•; anJ our
Free Serl'ti:e Loan Car Pro_qram.

$3 ]9 mo.

endeavor, such as teaching, research,

50 mo. !ea.Je

$0 down

practice, or community service.
Michael E. Cohen, M.D. '61 (top left), is a neurology professor at UB.

IN FIN IT I

Robert E. Reisman, M.D. '56 (top right), is an allergist in Buffalo. Edward
Shanbrom, M.D. '51 (bottom), is retired from his internal medicine

AUTO PLACE INFINITI
8129 MAIN ST., WILLIAMSVILLE

633-9585

practice in Santa Ana, CA. All are pictured with Margaret Paroski, M.D.,

East of Transit Rd. ,
Near Eastern Hills Mall

the outgoing president of the Medical Alumni Association.

G20 42 moJ130 42 mo. lease with cash or trade equity
down. (G20-$495) (130-$450). Bank fee + tax and
license due at inception. 12,000 annual mileage. $.12
per mile 1n excess.

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Spring Clinical Day
and Reunion Weekend '96

SALE

OR

LEASE

CONTEMPORARY

MEDICAL OFFICES
Spring Clinical Day (May 11) kicked off a lively
reunion weekend. Alumni from the past SO
years attended the Stockton Kimball lecture,
CME panel discussions, and poster exhibits at
the Buffalo Marriott. But the weekend's social
events, receptions, and dinners also provided
plenty of time for meeting old friends and
making new ones.

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;

HURWITZ &amp; RNE, PC.

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5

CARLJ . STREICHER '35 ,

of Lake Havasu City, AZ,
ha retired from his ophthalmology-otolaryngology
practice. He writes, "After a
direct experience with insertion of a stent into a coronary artery, I am now as active as a golrer rive
days a week can be, and hope to continue in
this career for some tune! "
BERNARDS . STELL '36 ,

FRANKL. TABRAH '43,

SERVICI G

in the Department of Physiology at the Uni-

THE LEGAL

versity of Hawaii's School of Medicine, and

H EALTH

Straub Clinic and Hospital.

recognized with a plaque from the Hidalgo• Managed Care

Starr County Medical Alliance for his lifetime
dedication to the citizen ofHidalgo and Starr

• Purcha e &amp; Sale of Practices
• Business &amp; Tax Planning

1

9

5

0

WILLIAM J . SULLIVAN '55 ,

5

of los Angeles,

CA, is self-employed in forensic psychiatry.

will be memorable: in May will be the 60th
anniversary of the granting of my M.D. de-

He is president ofW.j. Sullivan, M.D., Inc.

gree; the 50th anniversary of my having
earned an Cd.M. degree from the Millard
. of Buffalo; the 50th

• HCFA Safe H arbor Regulations

1

9

6

HARRIS FAIGEL '60 ,

0

5

of Waltham, MA,

anniversary of my induction into Phi Delta
Kappa, honorary education fraternity; and

pediatrics at Tufts School of Medicine and

the 50th anniversary of my membership in

was elected to the boards of the American

the American Psychiatric Association."

College Health Foundation and the American College Health Association. One son,

9

4

5

Douglas, is Hnishing a GI fellowship and
taking a position at the Portland (OR) VA

'40, ofjacksonville, FL, was

Hospital and Oregon Medical School; Faigel's

awarded a special citation by the American

other son, jordan, is a vice president at

Association of Retired Persons in appreciation

Paine Webber in New York City.

JOHN

D . WHITE

0

and Phys ician Self-Referrals
• Contracts with Private

was appointed associate clinical professor of

1

Scm CES

CoMMU ITY

of McAllen , TX, was

ciety of America. Stell adds, "The year 1996

Fillmore College at

N EEDS OF THE

director of th e Baromedicine Center at the

IVAN W . KUHL '45 ,

I

of Honolulu, HI ,

of Sun Cit), AZ,

the tereo Division of the Photographic So-

AT LAW

is emeritus professor of community health

Counties through his medical practice.

won the Master Stereographer Award from

ATTORNEYS

&amp; Public Entities
• Employee Relation
Counseling
• Fringe Benefit Programs
• Representation Before
Government Agencies on
Audit &amp; Bus iness Issues
• Facility Finance
and Construction

of outstanding service to the community.
of Pittsburgh ,
PA, was elected president of the Pennsylva-

• Credentialing

Hills, Ml , received the second annual Grad iva
Award from the ational Association for the

nia Academy of Ophthalmology at its an-

and By-Laws

Advancement of Psychoanalysis and the

Biglan is director of ophthalmology at

ALBERT W . BIGLAN '68 ,
ALEXANDER GRINSTEIN '42 ,

of Beverly

nual meeting in Pittsburgh March 29-30.

American Board of Accreditation in Psycho-

Children's Hospital of Pittsburgh, and con-

analysis for his book The Rcmwlwblc Bcatrix

sults for the Neonatal Intensive Care

Potter. The Gradiva Award, named for
igmund Freud's 1907 work, Delusions and
Dreams in jensen's "Gradiva," honors poets,

ery at Magee-Women's Hospital , the
Veteran'sAdministration Hospital , the West-

artists, writers, and others who create works

Rehabilitation Institute of Pittsburgh.

urs-

ern PA School for Blind Children, and the

• H ospital/Medical Staff Issues

Please contact
Robert P. Fine or
Lawrence M. Ross
at 716-849 -8900

that advance psychoanalysis. Grinstein's
of Orchard

book won in the category of childhood-

BERNARD C . MUSCATO '69 ,

related books. He was presented with the

Park, NY, has been appointed chair of Mercy

award on Apri l 20 at the annual

Hospital's Department of Obstetrics and Gy-

conference in

ew York City.

AAP

necology. He is past president of Mercy

1300 Liberty Building
Buffalo, New York

Hospital's medical staff and is serving a six-

®

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II

0

BARANSKI
ADVERTISING

•

I

THE ULTIMATE DRIVING MACHINE=
year term on the hospital's board of directors. Since 1974, he has been in private
p ractice at Hambu rg Gynecological and Obstetrical Group.

1

9

WILLIAM J.

7

0

5

was appointed

FIDEN '70 ,

clinical director of Erie Countr Medical
Center's Department of Familr Medicine.
He also serves a clinical assistant professor
at UB. A colonel in the

ew York Air

a-

tiona! Guard, he is clinic commander of the
107th Medical Squadron in

iagara Falls,

Checkpoint
Foreign Car, Inc.

NY. He and his wife, Susan, live in Buffalo.

Sales and Service

Medical College of Wisconsin . His daughter
Lisa, a sophomore at Duke University, will

Your advertising presents your
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Baranski A dvertising, we are
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ew York, publications where
your advertising message is sure
to reach a quality audience.

LAURENCE J . POHL '72 ,

of San Diego,

CA, recently received an M.P.H. from the

be taking herMCATin August1996, follow-

•

ing in her father's foots teps. Pohl writes that
his classmate, Michael Gordon '72, is the

487 Kenmore Avenue
Buffalo, NY 14223

most successful ophthalmology physician
in San Diego, do ing radial keratotomy.

836-2033

ERIC J .

RUSSELL '74 ,

of Chicago, ll,

currently serves as acting chair of the Department of Radiology at

•

orthwestern Univer-

sity Medical School and was elected treasurer
of the American Society of Neuroradiology.

Your WNY Leasing Specialist
Serving WNY proudly
for 33 years

His wife, Sandra K. Fern bach, M.D., recently
completed her term as president of the Chicago Radiological Society.

CALL US TODAY

REBECCA JACKSON SCHEITERLE '79 ,

(716) 645·6933

of Olean,

Y, is doing full-time emergency

medicine and is ER director at Olean General Hospital. She has four children: Stacy
(18), Zachary (10), Jonathan (8), and

MICHAEL J. BARANSKI

Kathryn (7). She was remarried injuly 1995
to Rick Scheiterle.

Marketing Representative
1

9

8

0

SU S AN STEPH E NS-GROFF '82 ,

P. S. We did this book!

5

of Phoe-

nix, AZ, pediatrician for Maricopa County
(AZ) Regional Schools, was honored as an
outstanding healer by the YWCA ofMaricopa
County at its third annual Tribute to Women

B

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l

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P

hysician

summer

l

9

9

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®

�•

···· · ··· · ······························· ·
;

Ifyou thought
you knew us...
do J.OU know

I

luncheon. She was chosen for her
extensive efforts to provide medical services to the poor, especially her work running the clinic
at the Thomas j. Pappas Regional

counseled their parents about the
limitations and possibilities of their
children's conditions. She was the
widow of RussellS. Kidder, M.D.

Center for homeless children.

ROBERT C . BAHN '4 7 diedApril

1

9

9

0

s

30, 1995,at his home in Rochester,
M . He was 69. He was emeritus

ROBERT P . P ITERA '90 , of
Holbrook, Y, recently com-

consultant in pathology and
anatomy at the Mayo Clinic. He
earned a Ph.D. in pathology from

pleted a lecture series at the
Beijing Hospital in the People's

the University of Minnesota in
1953. He had a longterm interest

Repub lic of China for the
hospital's 75th anniversary. "My

in the application of computers
to medicine and belonged to the

lectures focused on sports medicine with emphasis on diagnosis
and treatment." The series drew
over 100 physiatrists from all
parts of China. Interested alumni

Mathematics Association of
America and the Association for
Computing Machinery. Bahn also
played trombone and tuba with local groups, including the Rochester

can contact him at the Empire
State Building, 350 Fifth Ave.,

Civic Music Concert Band and

Suite 6606, New York, Y 10018
(212-293-7800), or at his home,

what's NE.W?

~"~~

., s~"s 'loJ·
._;;.~""'os"&lt;'"

• 14,000 sq. ft . of flexible
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Trombones Anonymous. His wife,
Miriam Ruth Huer, died in 1992.

405 Sadd le Rock Road,
Holbrook, NY 11741 (516-5638346). "It was great seeing everyoneatourfifth reunion. Keep
in touch and keep smiling."

And Your Choice
To Stay In WNY!

Buffalo Physician is on e-mail!
OBITUARIES
RUTH F . KRAUSS-KIDDER '4 3 ,
a respected member of the
Children's Hospital staff and
the UB faculty, died March 29,
1996, at the iagara Lutheran
Home. She was 75. Before

• A first-class hotel with outstanding
amenities, comforts and conveniences - centrally located at the
University at Buffalo Complex.

Our new address for
classnotes is

Rooms

bpnotes@pub.buHalo.edu.

associate professor of pediatrics in
UB's department of neurology. After graduation from UB's medical
school, she interned at the former

news about your fife, career,
or famay. Don't forget to
include your name, your home

BUFFALO~affiOft

address, and the year you

E.]. Meyer Memorial Hospital. She

joined Children's medical staff in

earned your MD from UB.

1340 Millersport Highway, Amherst, Y 14221
(7 16) 689-6900 or (800) 334-4040
At the University at Buffalo Complex

1945. As a pediatric neurologist,
she not only treated patients but

®

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Congrarulations
to The University at Buffalo School
ofMedicine &amp; Biomedical Studies on
celebrating I 50years ofteaching,
healing and research.'
FromTN'f-~

Please send us the latest

her retirement, she was director of
electroencephalography
at
Children's Hospital and clinical

,t\'ail.tbl~:

lJ B Alumni W~:~:k~:nd
Oc.tob~:r ·1-6, I 'J'J6

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�BUFFALO PHYSICIAN

Non-Profit Org.
U.S. Postage
PAID
Buffalo, NY
Permit No. 311

STATE UNIVERSITY OF NEW YORK AT BUFFALO
3435 MAIN STREET
BUFFALO NEW YORK 14214

ADDRESS CORRECTION REQUESTED

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OR. OEVILLO W. HARRINGTON, class of 1871, knew how to make his money grow. In fact, this man who in 1905 provided $5,000 through
his will for the University at Buffalo School of Medicine, is still supporting UB today through the endowment his bequest created.
THIS PERMANENT endowment in Or. Harrington's name has grown to over $300,000 and today it supports the famous
Harrington Lecture Series, which twice a year brings distinguished scientific speakers to the School of Medicine and Biomedical Sciences.
DR. HARRINGTON'S LEGACY to UB is just one of many bequests which have established permanent and important endowed funds at
the school. They enable UB to provide scholarships to outstanding students, enhance scientific research, support excellence in teaching and
meet the ever-changing needs of the school.
YOU TOO can provide the School of Medicine with a measure of permanence through a bequest. Proper estate planning helps you
develop a smart fi nancial plan. A charitable bequest provides the satisfaction that comes from planting a tree under which you will never
sit, but which will bear fruit for generations to come.
FOR A CONFIDENTIAL consultation on making a bequest to the UB School of Medicine and Biomedical Sciences, or to receive
materials to share with your attorney or estate planning advisor, please contact:
STEPHEN A. EBSARY, JR.
Assistant Dean and Director of Development, School of Medicine and Biomedical Sciences

UNIVERSITY AT BUFFALO (716) 829-2773
U N I V I!:IIISITV AT .UFFALO
SCHOOL 01" MEDI C INI!:

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                    <text>State University of New York at Buffalo School of Medicine and Biomedical Sciences, Winter 1997

�BUFFALO PHYSICIAN

Volume 31,

umber l

ASSOCIATE VICE
PRESIDENT FOR
UN IVERSITY SERVICES

Dr. Carole Smith Petro
DIRECTOR OF
PUBLICAT IONS

Kathryn A. Sawner
EDITOR

jessica Ancker
ART DIRECTOR/DES IGNER

Alan j. Kegler
PRODUCTION MANAGER

Ann Raszman n Brown
STATE UNIVERSITY OF
NEW YORK AT BUFFALO
SCHOOL OF MED IC I NE
AND BIOMEDICAL
SCIENCES

Dr. john Wright, Interim Dean ,
Vice President for Clinical Affairs
EDITORIAL BOARD

Dr. Bertram Portin
Dr. Martin Brecher
Dr. Harold Brody
Dr. Richard L. Collins
Dr. jack F. Coyne
Dr. Alanj. Drinnan
Brian Duffy
Dr. james Kanski
Dr. Barbara Majeroni
Dr. Elizabeth Olmsted
Dr. Charles Paganelli
Dr. Stephen Spaulding
Dr. Bradley T. Truax
Dr. Franklin Zeplowitz

Dear Alumni and Friends,
UB's SESQUICENTENNIAL EVENTS WILL END with the award by the SUNY
Board of Trustees of an honorary doctor of science degree to Dr.
james Holland at commencement on May 11, 1997. Dr. Holland, the
Distinguished Professor of eo plastic Diseases and the director of the
Cancer Center at the Mount Sinai School of Medicine and Hospital
will also participate in teaching students in medicine, and will
present a Harrington Lecture during the course of the weekend.
Between now and the closing events of May 11, two additional
special activities are planned. The first, on Feb. 21-22, 1997, will be
held in connection with University Founders Day. Franklyn Knox,
M.D. '65, Ph .D. '65, formerly dean of the Mayo Medical School and director for education
of the Mayo Foundation, will be honored by a special symposium coordinated by the UB
Department of Physiology. He will present a Harrington Lecture, entitled "The Kidney
Performs Under Pressure." The SUNY Board of Trustees will also confer the honorary
doctorate of science degree upon him as part of the sesquicentennial festivities.
A very special event will focus on advances in medical education. It will be held on
April25, 1997, the day before the annual Spring Clinical Day meeting. Four major leaders
in medical education who had their roots at UB will return to join other faculty with whom
they had worked, in addition to the current generation of medical education leaders at the
medical school, to discuss the past, present, and future of medical education. The four are
Dr. George Miller, Dr. Steven Abrahamson, Dr. Edwin Rosinski (Ed.D. '58), and Dr.
Hilliardjason (M .D. '58, Ed.D. '62) .
As the sesquicentennial activities draw to a close, it is my observation that each served
to reconfirm the medical school's commitments to the intent of its founders and to provide
excellence and leadership in education, research, patient care, and community service. As
medical education and health care enter into a new, challenging era, UB stands ready to
maintain its professional integrity, while preparing to make its contribution to the
necessary growth in knowledge and needed advances that lie ahead.

~·'~.~

TEACHING HOSPITALS AND
LIAISONS

The Buffalo General Hospital

Michael Shaw
The Children's Hospital of Buffalo
Erie County Medical Center
Mercy Hospital
Millard Fillmore Health System

John Naughton , M.D.
Vice President for Clinical Affairs
Dean, School of Medicine and Biomedical Sciences

Frank Sava
Niagara Falls Memorial Medical
Center
Roswell Park Cancer Institute
Sisters of Charity Hospital

Dennis McCarthy
Veterans Affairs Western
Healthcare System

ew York

©The State University of New York
at Buffalo

Buffalo Physician is published
quarterly by the State University of
New York at Buffalo School of
Medicine and Biomedical Sciences
and the Office of Publications. It is
sent, free of charge, to alumni, faculty,
students, residents and friends. The
staff reserves the right to edit all copy
and submissions accepted for
publication.
Address questions, comments and
submissions to: The Editor, Buffalo
Physician, State University of New
York at Buffalo, Office of Publications, 136 Crofts Hall , Buffalo,
NY 14260

Send address changes Ia: Buffalo
Physician, 146 CFS Addition, 3435
Main Street, Buffalo, NY 14214

Dear Fellow Alumni,
WELL, IT'S WI TER IN BUFFALO ONCE AGAIN. We brace ourselves for the
cold weather ahead, and follow our Bills. But something is different.
Things are not the same. Someone is not here. It is the individual who
has directed and guided our medical school for the past 21 years,
Dean john Naughton, M.D.
When I was talking with him about some of his accomplishments,
he quickly turned the discussion to one of h is favorite interestssearching his family tree. As he speaks of his travels through Ireland
and the Northeast, you see a glimpse of the passion with which he
engineered this medical school into the 21st century. He follows no
model, but creates innovative ways to reach his goals. Hence, the reason why the Robert
Woodjohnson Foundation has provided UBgrants fo r primary care, and why he currently
chairs the New York State Council on Graduate Medical Education. His medical education
interests have centered on reform of graduate medical education, medical student
education, and collaborative and regionalized models of health care and education.
It's hard to envision our future without Dr. aughton's leadership. He will be tru ly
missed, but his legacy will live on in the students he has touched. Today's health care
system has certainly benefited and will continue to benefit from his vision, passion, and
dedication. Thank you, Dr. aughton!

Cover photo by K.C. Krall

Sincerely,

~cf2C'~~D
Jack F. Coyne, M.D.
President, Medical Alumni Association

�VOLUME 31 ,

NUMBER

1

WINTER

4~~~~ ~,~~~~~~~"~.0. 8

C~unch ~me

THE MANAGED CARE

NAUGHTON DISCUSSES HIS

REVOLUTION GOES INTO

CAREER FROM SPORTS

HIGH GEAR IN BUFFALO

WRITER TO CARDIAC

by Jessica Ancker

12

97

Making histo~y in the
histo~y of medicine
U 8'S TREASURES

ON

DISPLAY

photos by K.C. Kratt
RESEARCHER TO DEAN.

II

..JOHN R. WRIGHT,

M.D.

NAMED INTERIM DEAN

2

Then and Now
WHEN THE GERM THEORY

WAS STILL A

THEORY

by George F. Haddad, M.D. '94

3

Research

Alumni
RADIOLOGIST WENDE W.
LOGAN-YOUNG ,

GRANTS FOR BREAST

GENOME RESEARCH.

LIJ:¥UID

VENTILATION .

2

Medical School News

Astudent's perspective

NEW BOSNIA PARTNERSHIP •

A

..JOHN BORDER, M.D.

IDEALISM INTO PRACTICE

PRIMARY CARE EXTERNSHIPS.

by Christopher J. DiMaio, Class

..JOHN KOLEGA,

of 2000

PH.D. THE

NPR CAREER OF US's

MIRIAM SHUCHMAN,

'61.

..JACK RICHERT RETIRES.

CANCER AND HUMAN

POLICE SUICIDES.

M.D.

M.D.

CHANCE TO PUT

3

Classnotes

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$1.6 million funds study of
alcohol and breast cancer
an drinking alcoholic beverages
increase the risk of developing
breast cancer? If the answer is
"yes," as many scientists suspect,
what are the mechanisms involved, and are some women genetically more susceptible to the risk
than others?
University at Buffalo scientists will
attempt to answer these and other questions about alcohol through a $1.6 million grant from the U.S. Army's special
program for breast cancer research .
The study was led by] o Freudenheim,
Ph.D., UB associate professor of social
and preventive medicine.
"There is a fair amount of evidence
that alcohol may be related to breast
cancer, but most research has used inadequate measures of alcohol intake,"
Freudenheim explains. "We will be
making careful measures of lifetime alcohol consumption, as well as collecting data on diet, physical activity, and
reproductive history.
The researchers also will assess genetic differences in the way individuals metabolize alcohol, and will compare breast cancer rates among "fast "
and "slow" metabolizers . A
specimen bank
will be created to
store
blood
samples for current and future
research .
The
study
group will be
composed of
1 ,350 women
from western
New York with
breast cancer
and 2,030 randomly selected Jo Freudenheim, Ph.D

0

healthy women to serve as controls.
Participants will be between the ages
of 35 and 79.
Researchers theorize that alcohol may
influence the development of breast cancer by changing the body's steroid hormone levels or by increasing oxidation.
These mechanisms are among those that
will be investigated in subgroups of the
study population.
The research is an offshoot of an $8
million investigation of alcohol and
its relationship to chronic diseases
being carried out jointly by UB's Center for Preventive Medicine and the
Research Institute on Addictions in
Buffalo. +
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UB liquid ventilation study
proves eiTectiveness
artial liquid ventilation is safe
and effective for premature infants, according to research
from UB that appeared as the
lead article in theSept.l2 , 1996,
issue of the New England journal of Medicine .

A five-center trial of partial liquid
ventilation to treat lifethreatening respiratory
distress syndrome in extremely premature infants has shown that the
procedure is safe and effective , and that it improves lung function in
some children who
failed to respond to conventional treatment, increasing their chances of
survival.
Corrine Leach, M.D.,
UB assistant professor of
pediatrics , headed the
multi-center investiga-

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tion of the procedure, which was developed by Bradley Fuhrman, M.D ., UB
professor of pediatrics. Both practice at
Children's Hospital of Buffalo.
Respiratory distress syndrome , the
leading cause of death in premature
infants, develops when the lungs of
these tiny babies are unable to secrete
surfactant to prevent the air sacs from
collapsing.
Partial liquid ventilation (PLV) involves introducing an oxygen-rich liquid called perflubron into the baby's
lungs . The liquid allows the lungs to
inflate and permits oxygen and carbon
dioxide to pass through the air sacs and
into the blood stream more easily and
efficiently.
"The successful introduction of liquid into the lung and the ability of
infants to breathe with liquid allow
us to ventilate the lung at lower pressure , which causes less damage ,"
Leach explains. "If we can decrease
the amount of lung injury , we can
greatly improve the patient's outcome
and perhaps prevent chronic lung disease."
The pilot study involved 13 infants
born between 24 and 34 weeks of gestation. All had failed to respond to
conventional therapy and were at risk
of death .
Carbon dioxide levels improved in
all patients while on PL V; lung functioning improved in 11 infants.
Seven of the 13 critically ill infants
survived. Of those who died , three
succumbed to their acute lung disease, and one to bronchopulmonary
dysplasia. Two patients died of nonrespiratory complications of prematurity.
Clinical trials using PL V to treat
children and adults with severe respiratory distress syndrome are now
under way. Results are promising,
Leach says. +

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Reorganizing the
Human Genome Project

Former trooper studies police
suicide rates

a pretty good indicator of what's going
on out there ."
Results appeared in the American]our-

s part of a nationwide project to
combat ethical and image problems with the Human Genome
Project, the federal government
has given Roswell Park Cancer
Institute researchers a grant to
build a new human gene library.
The same Roswell Park research
group , which is led by Pieter Dejong,
Ph.D. , also won a grant to begin gene
sequencing. They will share the $2 million Department of Energy pilot grant
with a team at the University of TexasSouthwestern.
The National Center for Human Genome Research decided there was a need
for new gene libraries after finding problems with the way researchers had obtained DNA samples in the older libraries.
The federal administrators found that
most of the DNA in the four best gene
libraries (including Dejong's) came from
only four people, rather than from a
diverse group of donors. They also found
that some of the subjects may not have
been fully informed of what their donation would be used for, and that several
of the donors were known to the researchers and so were not anonymous.
Under new ethics guidelines, researchers will recruit a larger pool of donors
and follow procedures to ensure donors' anonymity and to obtain their
informed consent. They will also follow
additional rules to combat image problems. For instance, researchers may not
donate their own DNA (because it might
appear "elitist") or ask junior lab members to do so . They must also recruit a
substantial number of women donors.
According to Dejong, a UB associate
research professor, sequencers will continue working on the old libraries during the two years it will take to create
the new ones. +

olice officers are eight times more
likely to die by their own hand
than by homicide, a study by University at Buffalo epidemiologists
has shown.
They also take their own lives at
a much higher rate than other municipal employees, the
findings indicated.
The study is one
of the few empirical analyses of police officers' risk of
suicide, homicide ,
and
accidental
death, and the only
study to compare
their risk to that of
other workers.
"We are hoping
this study will make
the police community aware that suicide is a problem,
not a myth , not
something that
should be shrugged
aside, " says lead author john M. Violanti, Ph.D., a UB assistant clinical professor who is himself a
23-year veteran of the New York State
Police.
Violanti, along with john E. Vena ,
Ph.D. , and other colleagues from the
UB Department of Social and Preventive Medicine, analyzed mortality data
for the 138 Buffalo police officers and
other municipal workers who died
between 1950 and 1990 of external
causes.
According to Violanti, the Buffalo
statistics mirror those of police departments around the country. "We
looked at five other cities, and all five
departments were higher in suicide
than other occupations . I think this is

The researchers identified a number
of potential factors in the police suicide
rate, including continuous exposure to
human misery, an overbearing police
bureaucracy, shift work, social strain,
marital difficulties , inconsistencies in
the criminal justice system, alcohol
problems, physical illness, impending retirement, and lack of
control
over
work and personal life.
Easy access
to handguns and
the lack of confidential counseling may also be
factors ,
says
Violanti.
"Police officers are even more
hesitant than the
average citizen to
get help for emotional problems,"
he notes. "Because of their role and their job, they
mistrust many things , and they especially mistrust mental health professionals. The other half of the problem is ,
confidential help isn't always readily
available.
"Departments should include some
sort of suicide awareness training in
their stress management program,"
Violanti adds. "The New York City Police Department has such a program
and suicides went down after it was
instituted. The Buffalo department now
also has a program in place. "
The research was supported by a grant
from the National Institute of Mental
Health. +

-JESSICA

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�Naughton discusses his career
from sports writer to
cardiac researcher to dean at UB
As]OHN NAUGHTON, M.D., 63,stepsdownafter21 eventful
years as dean of the medical school, he can be certain he's
secured his place in UB history.
Conversely, UB can be sure it has secured its place in
Naughton's own eventful history, which began far from
Buffalo or any other academic center.
John Naughton grew up about 80 miles from Oklahoma
City in Lawton, OK, at the time a town of 14,000 people.
Lawton's business community, including the Naughton
family's restaurants, depended on servicemen visiting from
the nearby Fort Sill military post and training center.
Young jack, as he was called, did
well in school and also worked hard
at a number of different jobs. Helping
out at his father's restaurants , the
Chuckwagon and jack's White House
Cafe, "taught me just about everything there was to know in the restaurant business." He also worked
part time as a sports and news writer
for the Lawton Constitution. "I was a
good writer-my strong point was
writing lead sentences," he remembers with pride.
Naughton earned an associate's
degree from Cameron State College,
a two-year school in Lawton where
he was the editor of the
student newspaper. But he
had higher aspirations: he
went on to St. Louis University to earn a B.S. in
preparation for medical
school.
"My interest in medicine, I think, came from my

mother. She had been a nurse before she was married, and always
wanted to have a doctor in the family," Naughton says. "At the same
time , my father , as an independent
businessman who was very active
in each community he lived in , gave
me an appreciation of the importance of community service. That's
something I consider to be part of
medicine, too. "
When he entered college,
Naughton found that he was far behind some of his contemporaries in
basic science education. "Lawton was
a very small community, and we didn't
have a lot of kids who
went into academic fields.
"Looking back on it, I appreciate Lawton, because
I grew up among real
people who sometimes
academics and medical
students don't have a
chance to know," he says.

bx !essica Ancker

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Naughton earned his M.D. from the
University of Oklahoma, did a mixed
medical internship at George Washington University, and completed a residency and post-doctoral work at the
University of Oklahoma Medical Center
where he remained until 1968 as an
assistant professor.
While his early research interest was
the effect of emotional stress on the
heart, he soon began investigating the
effects of physical stress and ways to
rehabilitate patients after heart attacks.
"In a time of national emphasis on fitness during John F. Kennedy's presidency, we were looking at broad national questions , not just the effects of

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tests on individuals. Our question was ,
in an unfit society, could unfit people
be reconditioned and would it improve
the quality of life? "
a ugh ton then moved to the University of Illinois, where he became an associate professor and the director of the
school's Rehabilitation Center. Later, at
the George Washington University Medical Center, he became director of both
the Division of Rehabilitation Medicine
and the Regional Rehabilitation and
Training Center. He also directed the
ational Exercise and Heart Disease
Project, a national study that he continued to head until its final report in 1983.
It was at George Washington that

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Naughton got his first taste of administrative life , becoming dean of academic
affairs in 1973.
"Even though I loved being a researcher, I had also always been interested in teaching and in broader areas of
medical education," he explains. Heremembers being trained to be a first-rate
internist, with only secondary emphasis
on developing a specialty. By the time he
joined the University of Illinois, emphasis on the core of medical education was
already disappearing in favor of training
specialists.
"That alerted me that there were interesting issues in medical education.
My interest was in providing a medical

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education that served a broader need in
society."
Naughton accepted the deanship of
UB's School of Medicine and Biomedical
Sciences in 1975 at the age of 42. He was
eager for the chance to lead a school,
and he describes a mix of other reasons
that made UB's offer intriguing.
First, he says, he wanted to join a
public university, with its commitment

0

to serving the people of its state. He also
liked the fact that UB was an integral
part of the Buffalo community. "Medical education should be serving the
community in some way."
Also, Naughton said he immediately
felt that UB had never taken full advantage of the resources at its fingertips.
For example, UB's outstanding faculty
weren't getting recognition at the national level, and they were rarely invited to join state Health Department
committees.
"Things other people saw as disadvantages, I saw as opportunities. That
probably comes from my rehabilitation
career!"
Coming on board at a time of sagging
morale, low prestige, limited research
funding, and uncertain priorities in the
wake of the merger with SUNY,
Naughton helped raise the school to
national stature.
One achievement that will always be
linked with Naughton's name is the
creation of the Graduate Medical Dental Education Consortium of Buffalo.
More than just coordinating resident
education, the consortium has become
a symbol of the cooperation among the
hospitals, which have reduced duplication, saved money, and concentrated
their expertise by designating certain
hospitals to develop into regional centers of specialty services.
Interestingly, Naughton also counts
as a success his hospital consolidation
study, which stirred public controversy
and was never implemented. He had
been invited by Buffalo General Hospital, Children's Hospital of Buffalo, and
the former E. ] . Meyer and Deaconess
hospitals to head a study on the feasibility of mergers. The resulting report recommended a series of consolidations to
cut down on unused beds and costly
duplication of services. The plan failed
by one vote to pass in the Erie County
legislature, due to opposition from community groups, politicians, and some
parts of the medical community.
"However, that study served to create the image of the medical school as a

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leader in Buffalo's medical community.
It was also the first opportunity to bring
people from the different hospitals together in a more cooperative way. It set
the stage to found the consortium."
Naughton is credited with many
other accomplishments at UB, including beginning the Primary Care Resource Center, winning the Robert
Wood johnson Generalist Physician
Initiative grant, building and renovating university buildings, and establishing a strong affirmative-action policy.
The dean is looking forward to returning to research, teaching, and
men to ring new generations of students
and doctors.
"The things I came to UB to accomplish, I think I have accomplished. You
get a certain thrill and high out of that,"
he says. "We now have a sense of institution. We have stature as a medical
school, and it's not just dependent on
one or two outstanding individuals.
"I am looking forward to the next
few years as an academic." +

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�INTERIM DEAN APPOINTED
ohn Wright, M.D., will serve as interim dean and vice president for
clinical affairs until a new dean is appointed.
Wright, the chair of the Departments of Pathology at UB and Buffalo
General Hospital, earned his M.D. at the University ofManitoba in 1959.
He completed a residency at the Buffalo General Hospital and then held
a National Institutes of Health fellowship in endocrinology there.
Between 1965 and 1967 he held a Buswell Fellowship at UB.
Wright taught at johns Hopkins University School of Medicine before
joining the UB faculty in 1974. Among many other appointments, Wright has
served as interim director of Roswell Park Cancer Institute and as director of
the university pathology residency program.
Wright says he hopes to continue john Naughton's initiatives
in reorganizing the Faculty Practice Plan, reorienting medical
education toward a primary care perspective, and providing
support for the student body. He also hopes to keep the medical
school involved in the merger negotiations between the Buffalo
General, Children's, and Millard Fillmore hospitals. +

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�BY

JESSICA

The managed care revolution
goes into high gear in Buffalo
lue Cross and Blue Shield of Western New York set off a
firestorm of criticism last year when it introduced Community Blue Advantage, a plan that lets patients opt for
lower copays and more services in return for a more
limited selection of hospitals and doctors.
In another city, this might have been accepted as just another
insurance option. In Buffalo, it was considered outrageous. One
state legislator accused the company of a "callousness" that was
"frightening," and the county medical society at one point
demanded an immediate halt to the plan's marketing campaign.
Reaction might not have been so
strong if doctors and hospitals hadn't
already been feeling squeezed by fastmoving changes in Buffalo's health-care
economy. Two factors here are compressing and accelerating a market evolution that is familiar to much of the rest
of the country.
First, a statewide Health-Care Reform Act is changing the playing field
for New York State hospitals in 1997.
New York had been one of two holdout
states that still set hospital reimbursement rates for most insurers; now, all

0

insurers are free to negotiate these rates .
Second, managed care is rapidly coming of age in Western New York. While
about 30 percent of New York State's
population is enrolled in managed care
plans, the rate is almost 50 percent in
Buffalo. The figures will increase, particularly because state officials hope to
enroll 2.5 million Medicaid recipients
in managed care in the second step of
health-care reform.
So the state has stripped hospitals of
some protected rates at the same time
that managed care is driving down hos-

Buffalo

ANCKER

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pitalization rates. And looking ahead,
both insurers and providers fear that
for-profit companies will soon move
into Western New York.
These converging forces have produced a burst of competition in the
health-care field . Patient care is rapidly
moving out of the relatively expensive
hospital setting, hospitals are facing low
occupancy rates, and insurers are finding new ways to manage care and to
share financial risk with doctors.
"It took southern California 20 years
to be changed by managed care. It took
about eight years for Boston. We're going to do it in 18 months ," predicts jack
M. Sieber, a health-care consultant at
Ernst&amp;: Young, LLP.
"I think we're going to leapfrog some
of the steps that other regions went
through," agrees Robert V. Stanek, chief
executive officer of Mercy Health System of Western New York. "That's a
double-edged sword. On one hand, we
learn from what's happened elsewhere.
On the other, the rapidity of the change
will be difficult. "
These are some of the changes Buffalo will see in the near future :
of? A wave of hospital mergers that
could consolidate nearly half of the
region's hospital beds into two systems;
of? Reimbursement systems that split
risks between insurers and providers;

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7 Less money for residency training,
which may translate into fewer residency slots;
t" More interest by doctors in group
practices and other sorts of cooperative
arrangements that help them provide
patient advocacy and negotiate better
deals from payers.

Stages of economic change
The national health-care economy is
changing in fits and starts, and it's different in every city.
William L. Kissick, M.D., Dr.P.H. ,
has a unique perspective on the issue.
The author of Medicine's Dilemmas: Infinite Needs versus Finite Resources, Kissick
is a professor in the University of Pennsylvania Medical Center as well as Penn's
Wharton School of Business. In the
1960s, he served as a staff member to the
federal task force that created Medicare.
In a recent lecture in Buffalo, Kissick
outlined four stages of evolution in the
health-care market.
The first stage is the traditional system as many doctors fondly remember
it. Doctors practiced independently or
in small groups and were paid by insurers. There was not much push for lower
costs on the part of employers. Kissick
cites Syracuse, NY, as an example of a
community that is still in this early stage
of development.
The second stage of market evolution begins when managed-care plans
attract more enrollment, and hospitals
therefore find themselves contending
with lower rates of admission. Providers
begin affiliating in loose networks, but
are often still reimbursed on a discounted
fee-for-service basis.
According to Kissick, Buffalo is rushing into stage three. Managed-care providers have become larger, hospitals are
merging, and integrated systems are
beginning to link health-care financing
with health-care delivery.
Stage four , he predicts, will feature
more highly managed care, fully integrated health-care delivery and finance
systems, a high demand for primary
care doctors, and leaner times for specialists.

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Merging to save money
Western New York's seven Catholic
hospitals are well on their way to becoming an integrated system. They are
likely to include Niagara Falls Memorial
Hospital as an affiliate.
In addition, Millard Fillmore Health
System, the Buffalo General Hospital,
and Children's Hospital of Buffalo are
continuing talks toward a merger. They
have released few details about the negotiations except to announce that john
Friedlander has stepped down from his
position as Buffalo General CEO in preparation for leading the new merged entity.
"The health-care industry is going
down the same path as the banking,
railroads, and airline industries-we're
undergoing consolidation to provide a
better product from cost and quality
standpoints," says Stanek, the Mercy
Health System CEO.
The mergers offer the potential to save
money through consolidations and economies of scale. All the players agree that a
considerable fraction of the 4,700 hospital
beds in the Buffalo area are unnecessary,
although estimates of the figure range
from 15 to 35 percent. The mergers could
also put hospitals in a stronger negotiating position with payers because insurers
won't be able pit one hospital against
another or ignore a system that serves a
crucial geographic region.
Erie County Medical Center is pursuing another strategy, expanding to
form its own system with a network of
community primary-care facilities to attract more insured patients.
Creating a system (through mergers
or through expansion into the community) puts hospitals in a better position
because they can offer payers a full range
of services, better geographic coverage,

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and more direct control of costs, according to Sieber.
Some health-care experts also say
that in the future, full-service healthcare systems may contract directly with
large employers, bypassing insurers altogether.
A more immediate incentive for mergers is a fear that New York State will
drop its longstanding ban on for-profit
hospitals.
"There's a concern that if the law is
changed, a big national provider could
come in and scoop up whoever's not
involved in a system," says Sieber. "Most
people here would rather see community involvement and community control of the health-care system."
In addition, for-profit insurers from
New York City and from other states
have been putting out feelers in the
region.
Increased competition on top of the
state deregulation ofhospital rates would
have prompted mergers in any case. The
process is being speeded up by the fact
that managed care in Buffalo is already
so strong.
"It's a big change, to take away that
protection for hospitals at the same time
that managed care is mature," says
Arthur Goshin , M.D., president of
Buffalo's oldest managed care group,
HealthCarePlan. "In other states, either
there was no regulated reimbursement,
or managed care grew slowly."

State law changes the rules
New York's health-care reform package
does more than just deregulate hospital
rates. Among other things, it creates
new funding pools for graduate medical
education (GME) and for charity care.
The changes are intended to stop the

0

�common practice of using GME dollars
to help support a hospital's charity care
and bad debt. They are also an attempt
to reduce the number of residents trained
in New York and bring the number
closer to the national average of30 to 35
residents per 100,000 population.
As a result, Western New York hospitals , which train 40 to 45 residents per
100,000 people, will face a $13.9 million
loss in GME dollars, according to] ohn P.
Naughton, M.D., who recently retired
from his position as dean of the School of
Medicine and Biomedical Sciences.
While there is concern about how
the reforms will affect the future of
medical education, doctors are welcoming other parts of the health-care reform
law that protect patients and doctors .
Among the law's provisions: an absolute
ban on "gag rules;" guarantees that qualified doctors will be involved in decisions about whether to cover specific
procedures; and grievance procedures
for patients denied care and for doctors
dropped from insurance plans.

Doctors share risk in new
payment schemes
Buffalo's managed care entities-mostly
Independent Health Association ,
HealthCarePlan, and Community Bluetogether enroll almost 50 percent of the
area's population (80 percent of the commercially insured population) .
But until quite recently, Sieber says,
most managed care companies in New
York State have operated through discounted fee-for-service systems, so they
weren't that different from indemnity companies. "We called it 'managed care lite."'
"It's really been 'indemnity in drag,"'
agrees UB's chair of family medicine,
Thomas Rosenthal, M.D.
As the market grows more competitive, managed care groups are altering
theirreimbursement plans. For example,
Independent Health Association, an independent practitioner association/managed care organization, has introduced
a new system of modified capitation
(prepayment on a per-patient basis).
HealthCarePlan continues to reimburse physicians on a 'withhold' system,
in which the insurer prepays doctors up

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to 85 percent of agreed-upon fees , but
withholds the remaining 15 percent until the end of the fiscal year. Doctors who
worked within their budgets then get the
entire 15 percent; higher costs are deducted out of the withheld money. As an
additional incentive, says president
Arthur Goshin, physicians will be told
the rates charged by hospitals. That will
give doctors a reason to prefer hospitals
where HCP has negotiated low rates.
Blue Cross and Blue Shield negotiates different types of reimbursement
with different providers, says Nora
McGuire, the executive director of Community Blue, the insurer's HMO.
Sieber says there is room for a variety
of reimbursement systems. "Capitation
is the buzz word today, but it's only one
form of sharing risk. It's quite possible
that no single method will dominate the
market. "
Companies are also creating new
types of plans. HealthCarePlan, originally a staff-model HMO, recently added
a preferred-provider network called
Choice Care. But for many physicians, it
was Blue Cross and Blue Shield's new
HMO product that came to symbolize a
threatening level of change.
In essence, the company divided its
HMO, Community Blue, into two parts.
One is the traditional HMO in which
patients are responsible for copays for a
range of services. The alternative, Community Blue Advantage, offers additional
dental, optical, and other services, lower
copays, and medical care from a subset
of the plan's doctors and hospitals. Patients can go to doctors outside the
network for an additional fee .
McGuire , the plan's executive director, says hospitals were chosen to participate in Advantage based on the rates
they negotiated with the plan. The plan
selected doctors based on factors that
included cost, geographic distribution,
and hospital affiliation. The plan resulted in complaints from hospitals and
doctors not included in this abridged
roster, although Community Blue managed to soften the criticism after adding
ECMC to the Advantage plan and holding talks with the Medical Society of
Erie County.

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Best practices
Insurers are also doing more to manage
care by trying to standardize the way
different doctors practice. In part, they
do this by providing outcomes data and
other research . Doctors and insurers
both agree that doctors are eager to help
set best-practice guidelines, and that, if
they are convinced of the value of the
guidelines, they willingly comply. The
desire to better serve patients, as well as
peer pressure from fellow doctors, can
both play a role.
"Doctors want to know the data because they want to use it in their decision making," says Gosh in, president of
HealthCarePlan.
"Physicians are scientists, and if we
direct those energies into getting the
best practices, we'll get the best outcomes," says Buffalo Medical Group
medical director Richard M. Peer, M.D.
"If it's imposed upon them, they will
rebel. If they understand the process,
and have input, they get enthused."
But that doesn't mean that insurers
and doctors will agree on what the best
practices are. Doctors are concerned
that insurance companies' business goals
will win out over quality concerns. Insurers suspect that doctors don't appreciate the importance of controlling costs.
In some cases, physician organizations can give doctors a greater say in
how insurers regulate practice. And
physician groups can also help doctors
negotiate better deals . As a result,
Buffalo's doctors are becoming more
interested in cooperative arrangements,
such as group practices , physicianhospital organizations, and independent
practitioner associations.
"Physicians in New York haven't been
very organized, but we're starting to see
more of that," Sieber says.
One of the area's largest and oldest
multi-specialty group practices is the
Buffalo Medical Group. It was formed in
1946 as a way to pool resources and
practice in an atmosphere of professional cooperation, but gradually its
business role has become more important. The group now handles all billing,
negotiates contracts with insurers, and
scrutinizes contract language.

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"If we feel it is to our benefit and to care doctors and giving them a strong
economy by realizing the possibility of
our patients' advantage, we will partici- financial incentive not to use specialty cost savings in insurances.
pate in an insurers' plan as an entire care, money is budgeted for primary
In 1984, there were 33 hospitals in
group," says Peer, a vascular surgeon care and for different types of specialty
the Twin Cities. Within four years, eight
who serves as the medical director.
care based on usage of specialty services
hospitals closed and most of the others
A different type of physicians' orga- in past years. Additional financial and
had merged into three systems. HMOs
nization is the University Medical Group, professional incentives are intended to
also merged and consolidated, and phyformed to organize UB's 400-plus physi- encourage specialists to follow certain sician groups grew larger in reaction.
cian faculty members. Its chief adminis- practice guidelines and to underspend The result is a variety of networks of
trative officer, Greg Brodnick, came to their pool's budget.
physicians, HMOs, and clinics that have
UB after a career with several Blue Cross
''I'm not suggesting this is the perfect shifted the provision of health care from
and Blue Shield plans in New York and way to pay doctors, but we also know
hospitals into community-based offices
Pennsylvania.
the pitfalls of the fee-for-service sysand clinics. A new state program,
"I certainly know the other side's phi- tem," Tronolone says. "At this point in MinnesotaCare, provides coverage for
losophy," says Brodnick. "That's what the health-care system, there is going to
the uninsured.
makes me valuable in this situation."
be an economic policeman. The patients
Buffalo may evolve along similar lines,
The group's bargaining strength would be best served by having people or it may find its own solutions, Kissick
comes from its diversity of generalists with medical knowledge do that, rather says. One of the critical factors is how
and specialists. Also, many of the fac- than the 'bean counters."'
doctors engage in the process.
ulty practice in the downtown hospitals
lawrence McCullough, Ph.D., a Baylor
that care for most of Buffalo's Medicaid What nowt
College ofMedicine professor who spoke
patients. This makes the doctors more Minneapolis was one of the first regions at UB's symposium on ethics and values
attractive to insurers who enter the Med- where the health-care economy began in health care, urged doctors to be more
icaid managed care market, because the to change, and it's one of the few that has assertive in their response to managed
insurers have to enroll enough doctors reached Kissick's fourth stage of ecocare. "I refuse to accept the victimology
to care for their new subscribers.
nomic evolution, managed competition.
language. Physicians are the most pow"Whenever you have big numbers,
The area has some similarities to
erful, well-organized profession in the
you have strength," Brodnick says. "Our Buffalo. Like New York State, Minnecountry. It's time to stop complaining
goal is to get our doctors signed on with sota prohibits for-profit hospitals. Minand start acting."
all the third-party payers. We can say, neapolis' population of 2.6 million is
He told doctors to accept the fact that
'Either you take all of us, or you get none about twice that of the Buffalo-Niagara all payment schemes would include fiof us."'
County region. However, unlike Bufnancial incentives, but urged them to
Another sort of physician group is the falo, Minneapolis has a core of powerful
fight to ensure that the incentives do not
Independent Practitioners Association of Fortune 500 companies, which spurred
cripple clinical judgment, that ethical
Western ewYork, which comprises the much of the change in the health-care
components are included in quality indoctors who work for Indicators, and that patients
dependent Health. The
are fully informed about
IPA is so integrally contheir insurance plans.
nected with Independent
Kissick urges providHealth that the insurer
ers and insurers to work
essentially pays capitatogether to ensure such
Carrie B. Frank has been appointed intion money to the docsocietal goods as conterim president and chief executive officer
tors' organization, which
sumer choice, low-cost
of the Buffalo General Health System.
then pays physicians. The
care, and organized
She succeeds John E. Friedlander, who
IPA's president, Michael
practice.
has stepped down to lead the developTronolone, M.D.,says the
"To manage or be
ment of a merged health care system that
IPA gives doctors a strong
managed,
that is the quesmay include Buffalo General, Children's
voice in the plan.
tion,"
he
says.
"Whether
Hospital of Buffalo, and Millard Fillmore
Tronolone says the
'tis
nobler
in
the
mind to
Health System.
doctors' group negotisuffer the slings and arFrank had been Buffalo General's exated a form of capitation
rows of outrageous forecutive vice president and chief operating
Carrie B. Frank
that spreads financial
tune, or to take up arms
officer since March 1993. Before that, she
risk among all types of
against
a sea of troubles,
had served in a number of financial roles, including vice president
practitioners. Instead of
and
by
opposing end
of finance and chief financial officer.
capitating the primary
them." +

New CEO named for the
Buffalo General Hospital

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In
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BROW\! HISTORY OF MEDICINE COLLECTION HAS BECO:YIE A LITTLE RICHER.

A first edition of a 16th-century obstetrical text donated to the collection this fall became the University Libraries'
3 millionth volume. And a $500,000 endowment by the History of Medicine Collection's strongest supporter will
enable the library to expand its unique collection.
Volume number 3,000,000 is a 1554 first edition of Jakob Rueffs De

GALEN

PERGAMUM,

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one of the most famous physicians of antiquity, practiced in Rome in the second century of the Christian era. His texts dominated medicine in Europe , Byzantium, and
the Arab countries for more than 1,000
years. This book, Galeni Pergameni omnia,
quae extant, in latinum sermonem con versa
(The surviving writings of Galen ofPergamum,
translated into Latin), is a compilation of his

writings published in Basel in 1561. The
detailed hand-coloring of the frontispiece
evinces the respect accorded to Galen's
name even at this date.

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conceptu et generatione hominis.
The Rueff book was presented to the University Libraries by George M.
Ellis, M.D., class of 1945. It builds on the strengths of the collection, which
was started by james Platt White, M.D. (1811-1881), a founder of the UB
medical school and its first professor of obstetrics. White's collection of
more than l ,000 medical texts was bequeathed to the university and became
the nucleus of the History of Medicine Collection.
The late Robert L. Brown, M.D. '44, was a strong supporter of the History
of Medicine Collection throughout his 25-year career in the medical school.
Brown, who at one point served as acting dean and later became the school's
first associate dean, supervised the merger with the State University of New
York. He also served as the medical school archivist, locating and preserving
historical records that otherwise would have been lost. In 1985, the year of
his retirement, the History of Medicine Collection was named after him.
Brown's $500,000 endowment to the collection is one of the largest ever
received by the library system.
The 12,000-volume History of Medicine Collection already houses a
trove of unique books, the oldest dating to 1493. In this issue of Buffalo
Physician, we introduce a few of them to readers.

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ANDREAS

HISTORY

THE

HISTORY OF M E D ICI

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VESALIUS

of Brussels revolutionized the study of anatomy
in the 16th century with detailed descriptions
and illustrations drawn from his own dissections. He generally suspended his specimens
from a pulley, so the organs and tissues in his
illustrations often appear to be dangling from
the cadaver. Because his observations updated and sometimes contradicted those of
the ancient authority Galen, Vesalius came
under fire from some critics who accused him
of disregarding tradition.
While the original sketches may have been
made by Vesalius himself, the woodcuts,
some of the most famous images in medical
history, are thought to have been carved by
assistants to the artist Titian.
Two hundred seventy-seven wood blocks
were created for the 1543 first edition of De
Humani Corporis Fabrica (Of the structure of
the human body) and an accompanying

abridged edition called the Epitome. Some of the original illustrations were replaced
by copies in later editions. UB's History of Medicine Collection owns one of these,
a fourth edition (the closed book shown above). The original blocks were lost and
rediscovered several times over the next few centuries as they passed through the
hands of collectors , artists, and librarians. The New York Academy of Medicine and
the Library of the University of Munich printed what would become the book' s fin al
edition in 1934, a copy of which is shown above and at right. The blocks were
destroyed in the Allied bombing of Munich in World War II.

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H 0 MIN Is (Of the conception and generation of men) was published by Swiss

obstetrician Jakob Rueff in 1554. The book's Latin text covers contemporary knowledge about conception, fetal development, uterine anatomy,
birth, and care of mother and infant. Rueff is believed to be the first author to recommend the use offorceps in live births . The woodcuts, although
in many cases derived from illustrations by Andreas Vesalius, also correct some flaws in Vesalius' representations of the fema le reproductive
organs. The woodcuts were carved by Jost Amman, who was also noted for his Biblical scenes. Shown here are depictions of abnormal
presentations of the fetus.
Presented to UB this year by George M. Ellis, M.D., UB class of 1945, De conceptu became UB 's 3 mill ionth library volume.

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HISTORY OF

MEDICINE

SURGEON

BRITISH

William Cowper published the first edition of
his popular Myotomia reformata, or an anatomical treatise on the muscles of the human body only three years after he entered
the practice of medicine. The 1724 edition
shown here, with its beautiful copperplate
illustrations and capital letters, was published posthumously.
During his career, Cowper identif ied the
bulbourethral gland and the fascia pectinea
ligament, both of which are now named after
him . He also published other works on hardening of the arteries and surgery of the
maxillar sinus.
One of Cowper's publications, The
Anatomy of Humane Bodies, became the
focus of a plagiarism scandal. Scholars believe he bought the copperplates to Anatomia
Humani Corporis, published in Amsterdam
by Govert Bidloo, and republ ished them with
his own English text and a new appendix.
Lacking modern copyright protect ions, Bidloo
retaliated by publishing a scathing attack
calling Cowper a literary crimina l.

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WILLIAM HUNTER'S TheAnatomyof

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ite! in figures reveals both his expertise in medicine and

the value he placed on art. Hunter and his artists and engravers worked for 30 years to create this book, which was published in 177 4 by John
Baskerville. Born in Scotland , Hunter practiced obstetrics and surgery in London . He opened his own School of Anatomy and lived on its premises ,
teaching and building his collections of anatomical specimens, rare books , coins , and paintings .

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THE

HISTORY

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STD UT ASS I STA

HISTORY OF MEDICINE

hold the pa ient's head firmly, and let others put their hands on

his arms and knees." Such practical advice for surgery before the advent of anesthesia is found in Bell's Great Operations of Surgery,
published in 1821 by the British surgeon Sir Charles Bell , who made a special study of the nervous system and was the first to describe
Bell 's palsy.
In his Great Operations, Bell detailed the tools and procedures used in such operations as trephining the skull, correcting hernias,
amputating limbs, and removing bladder stones. An accomplished artist, he also illustrated his own book.
In his advice to young surgeons, Bell draws on the experience he earned during his career in London and Edinburgh: "The extraction of the
[bladder] stone most requires patience, and a disregard to what spectators are thinking of you, especially fools with watches in their hands."
According to an inscription on the flyleaf, this copy of Bell was given to Roswell Park, M.D., in 1882 as a Christmas present. Park's own
signature also appears on the title page.

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a stonemason , was admitted to the hospital on March 20 , 1854, with debilitating
faintness and lack of appetite. He died the
next day. This hand-colored lithograph portrait of lveson in Thomas Addison 's 1855
book On the Constitutional and Local Effects of Disease of the Supra-Renal Capsule, illustrates the patient's overall pallor
and some smoky skin discolorations on his
face and chest. Addison was the first to link
the discolorations, the faintness, and the
weak pulse with autopsy findings of diseased supra-renal capsules (the adrenal
glands). The disorder, called Addison's disease , is now known to occur when tuberculosis or autoimmune problems destroy the
adrenal cortex and result in deficiencies of
aldosterone and cortisol.
This edition of Addison is exceptionally
valuable because it was presented to the
History of Medicine Collection by George M.
Thorn, M.D. , UBclass of1929, who was one
of the developers of the treatment for
Addison 's disease. The book is inscribed to
Thorn by " a grateful patient. "

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I

New faculty member is a
regular voice on NPR
hroughout her career, Miriam Shuchman, M.D., has drawn
on her medical expertise to write articles for the popular
press and to create broadcast commentaries and documentaries. Today Shuchman, a member of the psychiatry departments at UB and the Erie County Medical Center, is also a regular
medical commentator on NPR's "Medical Rounds."
A graduate of the University of Connecticut Medical School, she completed
her residency in psychiatry at Massachusetts General Hospital and Harvard
Medical School. Fellowships at
Dartmouth-Hitchcock Medical Center
inN ew Hampshire and the Robert Wood
johnson Clinical Scholars Program at
the University of California at San Francisco allowed her to pursue her interests
in consultation psychiatry and medical
ethics. She has also worked as a psychiatrist at San Francisco General Hospital.
Since moving to Buffalo in 1995,
Shuchman has been spending three days
a week at ECMC and the rest of the week
in Toronto with her husband, Don
Redelmeier, a physician on the faculty
of the University of Toronto, and their
son, 2-year-old Daniel.
Some of Shuchman's work for the
popular media has been in collaboration with Michael Wilkes, M.D., Ph.D.,
one of her classmates from both high
school and medical school who now
teaches at University of California at
Los Angeles Medical School.
In their first collaboration, an article
for the Hartford Courant newspaper
written while they were in medical
school, they discussed the medical
school socialization process that helps

turn a student into a doctor. Later, in
regular columns for the Los Angeles
Times and the New York Times,
Shuchman and Wilkes educated readers about such medical issues as clinical
depression, back pain, smoking cessation, and vaccines. Their writing caught
the attention of a National Public Radio
executive, who invited them to create
their monthly program for Weekend
Edition Sunday.
Their close professional relationship
shows in the smoothness of their fastpaced discussions on the radio program. One of them may begin an explanation of the day's topic, and hand it
over to the other to complete, as in a
well-rehearsed duet. They translate
medical terms into simpler language
that will be familiar to a lay audience.
When they disagree, they do so politely
but unapologetically.
In the week before each broadcast,
Shuchman, Wilkes, and NPR host Liane
Hansen hold a telephone meeting to
choose a headline-grabbing topic.
Shuchman then prepares herself with
a blitz of research. She combs through
professional journals and news clippings and interviews experts around
the country. She may ask professional
societies, such as the American Psychi-

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atricAssociation, to provide background
material, or seek the help ofNPRstaffin
collecting relevant news articles.
On a recent "Medical Rounds ,"
Wilkes and Shuchman discussed nonsteroidal anti-inflammatory drugs such
as Aleve. They pointed out that these
drugs can cause serious side-effects, including ulcers. Hansen asked whether
self-medication was dangerous.
''I'm not sure that medicating oneself
when it's a matter of having pain is such
a bad idea," Shuchman said. "You don't
want to always have to call your doctor
and say, 'I have this pain again, what do
you think I should do?' It does make it
easier for people that they can walk into
the drug store and talk to the pharmacist and say, 'I know that there are a
number of these drugs which are over
the counter. What do you suggest?"'
"I think I've got to disagree, Miriam,"
Wilkes responded. "I think that few
people talk to the pharmacist when they
buy over-the-counter drugs. I'm worried
about how many people end up in the
hospital with serious complications like
ulcer disease, etc., and even death, as a
result of taking too many of these drugs. "
The pair said later that the issue was
one on which they have long disagreed.
"Michael tends to wear a public health
hat, and I tend to wear an individual
patient hat," Shuchman said. "I really
think there's a limit to how much people
want to be protected from thingswhether it's in medicine or in something else, like the speed limit on the
highway. We know that a 55 mile-perhour speed limit is safer, but people
want to drive faster. "
Much of Shuchman's media work
focuses on mental health, including such
topics as the impact of violence on children who witness it and the value of talk
therapy and medication in the treatment of depression. She is working on a
radio documentary on schizophrenia
for the Canadian Broadcasting Corporation to be aired in spring 1997.

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the holUJayJ?

Tbefront-wbeel orive Infinitt-® /30TM

Miriam Shuchman, M.D.
Shuchman won the 1996 Media
Award from the Northern California
Psychiatric Society. It's unusual to get
such praise for her journalism work,
Shuchman says. "Far more often, you
get a letter from someone who disagrees
with you or is offended by something
you said." But, she says, she appreciates
even these letters.
She recalls one example, a "Medical
Rounds" program on a Supreme Court
ruling that protected patient-psychotherapist confidentiality.
"It's a stigma for people to find out
you've been in therapy. It can often
prevent you from being promoted at
your job," Shuchmansaid on the air. "So
the court was recognizing that people
have to know that what they say to a
therapist will be confidential in order to
feel that they can even go into therapy."
Shuchman also pointed out that religious confessions are generally considered privileged, and she described the
public outcry over an Oregon case in
which prison officials secretly recorded
a murder suspect's confession to a priest.
Within hours of the broadcast, Weekend Edition Sunday received an e-mail
from an Oregonian. "Dr. Shuchman pronounced the name of this beautiful state,
Ore-gawn," he wrote. "As every Oregonian knows, and as every easterner who's
never been here seems never to know,
IT IS PRONOU CED ORYGUN!!! as in
'He may have a knife OR A GUN!! '
Incidentally, people in Eugene are often

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offended when people say YOU-gene
rather than the correct pronunciation:
you-GE E. So, let's all say together,
'The taped Catholic confession happened
in you-GE E, Orygun."'
Although the letter may have been a
bit embarrassing, it did turn out to be a
learning experience. In a later "Medical
Rounds," Shuchman discussed state
measures on managed care, including a
proposition on the Oregon ballot. "Listeners might not have agreed with me,
but at least I pronounced the name of
the state correctly! "
She adds, "If I get letters that are very
moving, where people share their personal stories or have been offended or
hurt by something I said, I'll often call
back or e-maiL" In one case, after a
program on mastectomies and
lumpectomies, she spent several hours
on the phone with a listener who had
lost his wife to breast cancer.
Shuchman sees her two careers, medicine and journalism, as closely intertwined. Being a physician gives her the
credibility to influence the public's understanding of medical issues.
"I keep getting grabbed by stories,
coming from my patients, or my students, or the ideas that come up in
practice." +

"Medical Rounds" is broadcast once a month
as part of NPR's Weekend Edition Sunday, which is heard in Buffalo on Sundays
from 8 a.m. to noon on WBFO-FM.

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�Trauma surgeon
John R. Border dies
ohn R. Border, M.D., an internationally known researcher whose
pioneering work continues to save
thousands of accident and injury
victims from multiple-system
organ failure, died on Monday,
ov. 11, of a heart attack at his South
Wales, NY, home. He was 70.
Border, who joined the UB faculty in
1965 as a member of the Department of
Surgery, was director of the trauma
service at Erie County Medical Center
and director of UB's Trauma Research
Program from 1968 until his retirement in 1991.

In the early I970s, he led
nized and treated as soon as
a team of UB researchers in
possible after the original
developing treatment plans
trauma," he emphasized.
to prevent the stress of seMuch of the lifesaving
vere, multiple trauma from
research over the years was
producing a chain of biofunded through grants
chemical events that, if not
from the National Institreated with combination
tute of General Medical
protein and glucose therapy,
Services.
could lead to death.
Although officially retired,
Ina 1982 interview, BorBorder continued his work,
both locally and internationder explained that when the John R. Border, MD
. .
body does not receive adally, to improve the treatequate amounts of protein to meet in- ment of trauma patients. Wearing his
creased demands to maintain function trademark fire-engine-red suspenders,
and begin repair of damaged tissue, it white shirt and tan slacks, he regularly
draws on its own resources from muscle visited his office at ECMC.
and other vital organs.
The modest, soft-spoken Border
"The fatal sequence-multiple- trained hundreds of UB medical stusystem organ failure-must be recog- dents and residents during his career,

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HURWITZ &amp; RNE, P.C.
[ ATTOR
EYS AT LAW I
inspiring them by his example to not
only be good surgeons, but to practice
the art of the profession.
It was not unusual for him to sleep
overnight in his office at ECMC in case
a patient he was especially concerned
about needed him during the night.
A 1956 graduate of Harvard Medical

School, he did his undergraduate work
at Harvard College and Indiana University. He served in the U.S. Navy Submarine Service from 1944-48.
He and his wife, the former Donna
Orvedahl, traveled on the Great Lakes
and down the East Coast on their sailboat, Don]on II. +

SERVICING
THE LEGAL
NEEDS OF THE
HEALTH SCIENCES
C OMMU ITY
• Managed Care
• Purchase &amp; Sale of Practices
• Business &amp; Tax Planning
• HCFA Safe Harbor Regulations
and Physician Self-Referrals
• Contracts with Private
&amp; Public Entities

• Employee Relations
Counseling
• Fringe Benefit Programs
"It's ok to ploy!" said Ringling Bros. clown John Lynch. Lynch, the son of on endocrinologist, discussed
humor in medicine with students in Butler Auditorium while the circus was visiting Buffalo in November.

• Representation Before
Government Agencies on
Audit &amp; Business Issues
• Facility Finance
and Construction
• Credentialing
and By-Laws
• Hospital/Medical Staff Issues

Please contact
Robert P. Fine or
Lawrence M. Ross
at 716-849-8900

Fourteen physicians have completed UB's first Master's Teaching Fellowships, which offer training in
clinical teaching and precepting. Bock row: Thomas Scanlon; Michael Terranova; Jock Coyne; Richard
Carlson; Joe Lanigan; Sanford Levy; Anthony Vetrano. Front row: Tim Siepel; Donald Robinson; Colleen
Mottimore; C.V.P. Varma; David Novelli; Thomas Gerbasi. Not pictured: Richard Ruh.

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TRACING THE MOVEMENTS OF CELLS

When walls between research disciplines break down, the
change opens up new opportunities and new ways of
looking at old problems, according to cell biologistjohn
Kolega, Ph.D.

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muscle cells; specifically, the migration of the endothelial cells that
line blood vessels. These cells migrate during normal development
when blood vessels are formed,
and also during wound healing,
tumor growth, and diabetic blindness caused by blood vessels forming in the retina.
Kolega is attempting to establish how and when cells organize and distribute the motor
protein myosin II, and how cells
regulate the function of the protein. To watch cells move in three
dimensions, Kolega places them
in a collagen gel. Careful observations of moving cells are revealing how this molecule might
act to move different parts of a
cell as it crawls. A related project
that examines how electrical
stimuli affect the permeability of
a sheet of cells may shed more
light on cellular mechanisms of
blood vessel leakage.
Although some of the molecular structure and mechanisms are
beginning to be understood, it's
not known how they all work together. Visual imaging may provide some of the answers, Kolega
says. For example, he uses fluorescent imaging to examine spe-

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cific proteins within living cells as
they move.
"One of the things that is exploding in my field is the imaging
technology-the whole battery of
different forms of microscopywhich is allowing us to visualize
things in the cells that we could
never see before. Things that were
worked out by biochemists in test
tubes are starting to be seen within
the living cells. That is going to
take the tremendous advances in
molecular biology and translate
them into real biological behaviors. We can now start to watch
these things happening."
New discoveries in the field are
likely to be applicable to all cells,
Kolega says.
"I happen to be working on endothelial cells, in part because it's
easier to get funding for something
with clinical applications, but I like
to think that my work will help
answer the basic question of how
non-muscle cells migrate." +

John Kolega, Ph.D.
Cell Biologist

"It's no longer good enough to
know everything about molecules
or cells or organisms," he says. "The
really interesting things are going
on at the interfaces between the old
disciplines, where you have people
with different expertise looking at a
system from different levels."
Thanks to this new interdisciplinary emphasis in research and education, Kolega is now delivering
human anatomy lectures to firstyear medical students, in addition
to working with endothelial cells in
the lab.
Kolega, 38, earned his doctorate
at Yale and held post-doctorate positions at the National Institutes of
Health, New York University Medical Center, and Carnegie-Mellon
University. Upon joining the Department of Anatomy and Cell Biology at UB, Kolega took a crash
course in human anatomy so that
he could share the responsibility of
teaching basic preclinical courses.
He spent virtually every day of his
first year at UB in the anatomy lab.
"I was just one step ahead of the
students," he groans.
When not lecturing or supervising dissections, Kolega continues
his research into cell migration. His
field is the locomotion of non-

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ANCKER

�•

............... . ... . ................ . . . .......

~
I

Extemships provide a
taste of the real thing
ven with today's emphasis on clinical experience in medical education , it's not every second-year
student who gets to do an abdominal paracentesis or a flexible sigmoidoscopy. Clayton Polowy did.
"I had some serious hands-on experience as far as procedures went,"
Polowy recalled of his 1996 experience
in UB 's Primary Care Summer
Externship program. "It's basically primary care medicine and preventive
medicine at its highest degree ."
Polowy, now a third-year student,
was one of 7l first- and second-year
students in the program last summer.
The externship, which pays students to
spend the summer working with a primary care doctor, was developed in 1993.
Of the 55 externship participants who
have graduated from medical school,
more than two-thirds have gone on to

residencies in primary care.
"It's designed to give students a taste of reality in
Geraldine Kelly, M.D., supervises as student extern Mark Oberlies
terms of primary care mediexamines a patient.
cine," said Kim Crooks, who
coordinates the program at
UB's Primary Care Resource Center. "A certain. The current budget comes from
lot of programs are modeled after this one. a variety of sources, including the mediI get calls from all around the country."
cal school, the Robert Wood johnson
The six-week externship remains un- Foundation, and the state Department
usual in the large number of students it of Health. The Independent Health
enrolls and in the stipend it pays: $1 ,200 Foundation has also provided support
for first-year students and $2,000 for since 1995, and it recently decided to
those in their second year. That helps make a significant contribution for 1997.
push the annual cost to $125 ,000, but it "The goal of the foundation is to immakes it possible for more students to prove the quality of health in the combenefit from the full-time externship ex- munity, and we feel strongly that if
perience. ''I'm maxing out my loans," there is a large pool of primary care
said Polowy. "It was nice to feel that I physicians in the area, we're going to be
didn't have to work on top of doing that. " able to accomplish that," said joanne
Because it has no guaranteed source Way, the executive director of the founof funding , the program's future is un- dation, which is connected with the

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managed care company Independent
Health Association.
In addition, the Millard Fillmore Health
System, the Millard Fillmore medical staff,
and the Howard Wilding Memorial Fund
of the Millard Fillmore Health Education
and Research Foundation have made donations totaling $30,000.
The externship is a way of introducing students to clinical medicine and the
Buffalo medical community, said TimothyGabryel, M.D., vicechairmanofmedicine at Millard Fillmore. "It helps them
to see that what they went to medical
school for really exists," he explained.
"The best feedback for us is when we
see the enthusiasm in the students,"
said TonyBarthalomew, M.D., who with
his partner, jay Bishop, M.D., has been
an externship preceptor since the program started. It was at their Fredonia
practice that Polowy got his experience.
"In six weeks you really get to see a
lot," Polowy said. "One time, I did a joint
injection." He recalled how his preceptors would take the time to pull a book off
the shelf before discussing a procedure,
or would provide an immediate critique
of the way he interviewed a patient or
made a presentation. "I was always treated
by the staff and the physicians as a colleague," the student said.
Emily Calkins, another third-year student, was inspired by her 1996
externship with Deborah Richter, M.D. ,
in Buffalo's Geneva Scruggs and Mercy
health centers. "She was just a great role
model for me , which I needed during
medical school," said Calkins. "You see
so many social problems , and she
handled them so well. For many of these
patients she was the only place they
could turn for help. I keep her in the
back of my head at all times , wondering,
'What would Dr. Richter do? "'
Mark Oberlies, a third-year student
who has had two summer externship
experiences, said he was already interested in primary care, but he had a
nagging uncertainty about whether any

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uffalo

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physician could truly master the scope
of practice encountered by generalists.
"As a medical student you feel so
utterly clueless when there's so much
coming at you, " he said. "You just think,
'I've got to get to my little area of
medicine and learn everything I can
about it. ' At the same time you've got
people telling you to be a famil y doc
and take care of everything. I needed to
see if I could do that. "
Oberlies spent the first summer working with geriatric patients under June
Chang, M.D., and the second summer
with Geraldine Kelley, M.D., at Mercy
Hospital. "I take a lot of comfort from the
examples of these people," Oberlies concluded. "I have a lot of respect for the
people I've met in both externships. The
greatest success of the program for me was
that it showed me that primary care is
doable. People can do it, and do it well. " +
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UB and Buffalo General announce
new partnership with Bosnia

836-2033

fficials from UB met at the White
House on Oct. 2l for a ceremony to
announce a partnership to help
Bosnia rebuild its health-care system after years of war.
Leaders from UB, the Buffalo
General Hospital, and the city of Buffalo
were guests of Hillary Rodham Clinton.
Buffalo General has had an informal
relationship with Tuzla Clinical Center
for two years, through the efforts o[Jacob
Bergsland, M.D. , a cardiothoracic surgeon
and UB associate professor of surgery.
The new project, funded by $2 million from the United States Agency for
International Development, will offer
educational programs and the exchange
of clinical personnel. Nearly 120 healthcare professionals have already enrolled
in the program at the clinical center in
Bosnia-Herzogovina. +

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�THEN ~~AND~ N

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When the germ theory was still atheory
BY

GEORGE

HADDAD,

eorge Haddad, M.D. '94, is pursuing
a doctorate in the Department of the
History of Science and Medicine at
Yale University.
In his paper "Germ Theories, Scientific Medicine, and the Buffalo
Medical Community," Haddad argues that
there were numerous kinds of germ theories before Robert Koch's discovery of the
tuberculosis bacillus, and that much of the
local scientific debate was actually a "fixing of the meaning" of the phrase "germ
theory." He also shows that scientific advances did not move, ready packaged,from
European and American academic centers
to peripheral communities like Buffalo.
Instead, these smaller communities underwent their own periods of debate and upheaval before reaching consensus.
The following excerpts from Haddad's
work focus on the writings of one outspoken opponent to the germ theory.
Haddad's full paper, along with other
articles on western New York medical history, is being published in Medical History in Buffalo 1846-1996: Collected
Essays, by the Friends of the Health Sciences Library and the University at Buffalo School of Medicine and Biomedical
Sciences. Copies are available from History of Medicine curator Lilli Sentz at
(716) 829-3024.

Fighting the new theory

F

rederick R. Campbell was born in
Niagara County in 1860. He graduated from the Buffalo Medical College at age 24 and later joined the medical department of Niagara University,
where he taught "Hygiene" and "Materia Medica and Therapeutics." In addition to medical acumen, he had literary
and historical interests, and his schol-

M

D

arly output included a book entitled The into a certain lineage of medical theories, Campbell opened the germ theory
Language of Medicine.
In june of 1885, Campbell wrote an to criticism that other theories also faced.
Two years after Robert Koch's discovarticle entitled "Chemical vs. Germ
Theories of Disease" in which he offered ery of the tubercle bacillus, Campbell
a historical account of the dialectic be- realized that the role of doctors in the new
tween the "chemical-humoral" and germ theory world was about to change.
"germ-parasitic" theories of disease. just "When the germ theory becomes an esas the history of philosophy had experi- tablished fact," he scoffed, "the true phyenced a dialectic between idealism and sician will become a mere manipulator of
materialism, Campbell believed that germicides, and the pathologist a student
of microscopic
medicine, too , had
botany."
a specific sort of
This did not
dialectic between
mean Campbell
different theories of
was opposed to an
disease. He wrote:
"There was a huideal of scientific
progress in medimoral pathology of
cine. On the conthe Ancients, estrary, he saw
sentially a chemichemical theories
cal theory of disof disease and orease, replaced by
ganic chemistry as
the vegetable parathe legitimate heirs
sitic hypothesis of
to the scientific traVallisneri,
dition. He claimed
Hauptmann, and
that there were
Linaeus.
Then
"many honest sciStahl proposed a
entific men who
purely chemical
are unwilling to
theory of disease,
accept, in their
but this has been Frederick R. Campbell, M.D., in a portrait
present state, the
followed by the published posthumously in the BuHalo Medical
views
of the
germ theory, sug- and Surgical Journal.
'bacteriologists.'"
gested by the revIn his comparison of chemical and
elations of the microscope, and brought
to its present stage of development by germ theories, Campbell exploited the
such men as Virchow, Pasteur, Tyndall, optical limits of microscopy and offered
and Koch. "
a large number of well-articulated obBy placing the germ theory within a jections to a germ theory. For example,
genealogy of medical theories, Campbell microscopes of the time could not disstressed the contingency and contro- tinguish between bacteria associated
versial nature of a germ theory of dis- with very different diseases, and so, as
ease. Moreover, by placing a germ theory far as Campbell knew, they were identi-

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cal to each other. However, Campbell and antisepsis were mediated through
thought it was nonsensical to blame chemical processes. The germ theo"identical" bacteria for varying diseases. rists, according to Campbell, had
He also asserted that "bacteria and serendipitously, through erroneous
theories, fallen
micrococci are always found on the
upon the proper
surfaces of mucous
methods of surmembranes and
gical antisepsis.
these organisms
In a translation
differ in no respect
and commentary
from those found in
upon a French ardiseases." Moreticle published in
over, he denied the
the
Buffalo Medical
clayo al&lt;l, •llowiloc 'I" ......
contagiousness of
and Surgical jourtuberculosis and in- This laboratory sketch of cholera germs under the nal, Campbell exsisted that tubercu- microscope was published in the BuHalo Medical pressed his concern
losis could be and Surgical Journal by George W. Lewis, M.D.,
about the social
caused by a number a contemporary of Campbell's who defended
costs of accepting
of different, non- Koch's germ theory. At the time, it was rare for
the germ theory of
bacterial "irritating the journal to print any drawings or visual aids.
disease:
substances."
"As to the social
Campbell's "chemical theory," on the consequences, they have been seen in the
other hand, explained infectious dis- recent epidemics in Italy and the south of
ease by insisting that the introduction of France, where scenes of barbarism befit"some chemical substance" can result in ting another age were enacted. In Italy, it
disease. He believed that chemical poi- appears proprietors demand that persons, just like drugs or bacteria, could sons suspected of having phthisis [tuberhave "selective powers." Moreover, culosis] shall vacate their property."
In this piece, Campbell asserted that
Campbell believed that chemical theories offered a "more rational basis of laboratory scientists do not do as much
treatment than germ theories." Ulti- for practical medicine as "those who
mately, Campbell believed that a chemi- pass their lives surrounded by diseases."
cal theory of disease would be estab- Campbell's belief that he and the other
lished as fact once scientists studied opponents of a germ theory were depathological chemistry as well as patho- fenders of "true clinical medicine" reflects the cleavage in medical identity
logical anatomy.
Campbell ended his diatribe against that the germ theory controversy progerm theories by rhetorically equating duced. Campbell drew a clear line bebacteriologists with alchemists. Bacteri- tween the practice of traditional bedside
ologists "have already given the world medicine and the laboratory dabblings
many valuable discoveries," he began. of the new medical scientists.
In another Buffalo Medical and Surgi"] ust as the alchemists of old, while seeking the philosopher's stone and the elixir cal journal contribution, Campbell
vitae, brought forth what was even more scoffed at bacteriologists for claiming
valuable to mankind, modern chemistry, that they had discovered the true nature
so the microscopists have paved the way of disease and reminded them that they,
for the greatest discovery of modern medi- just as past believers in systems of medicine, were susceptible to new discovercine, surgical antisepsis."
By this, Campbell did not suggest ies and revisions:
"Were not the astrologists, the
that antisepsis relied on a germ theory of
disease. He firmly believed that sepsis humoralists, and the solidists of old

----......

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""'..._·_

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equally as certain as the modern bacteriologists, that they had discovered the
true nature of diseases? Who can say
that some writer in years to come will
not ridicule those 19th century doctors
who believed that microorganisms, like
the demons of old, produced diseases
in man?"
A laudatory obituary of Campbell appeared in the same issue of the journal.
His life ended at age 28. "He fell victim
to typhoid fever, after a sickness of over
a month," wrote the editors, who then
tactfully commented, "Indeed it may be
said that his death was the result of
overwork enfeebling a physical system
not robust and making it an easy prey to
disease."
Through modern hindsight,
Campbell may appear hopelessly unprogressive, but he can also be cast in a
sympathetic light. He did not study in
Europe, and he, like most other American medical school graduates, did not
have extensive training in microbiologic
techniques. He saw a germ theory as a
threat both to traditional medical
practice and to his own sense of
professional identity.
His opinions did not fall along expected generational lines, nor did his
opposition to a germ theory mean that
he was against a scientific ideal in medicine. In fact, Campbell repeatedly made
the claim that his "chemical theory"
was the true heir to the scientific tradition. In addition to his theoretical and
practical objections, Campbell saw a
germ theory as a threat to traditional
sources of professional identity.
Campbell believed that true doctors
spend their lives surrounded by the
sick rather than peering into a microscope.
His turn to the analysis of medical
history may just have been an idiosyncrasy of his personality. However, it
may reflect a greater tendency of physicians to make sense of changing values
and meanings by turning to the study
of medical history. +

�I
Achilllce to put idealism into practice
BY

CHRISTOPHER

J.

DIMAIO

have wanted to become a doctor since I was a child. I did not
have any life-altering experiences that led me to choose this
career. I simply loved science and wanted to indulge myself
in the highest level of science possible- human medicine.
Thus I find myself in the middle of my first year of medical
school, and I am loving it.
But let's face it. My life is not as rosy
as I may make it out to be. Ask any
medical student, myself included, a
seemingly harmless question like,
"How's it going? " and you will find
that you have just set yourself up for a
formidable avalanche of complaints
and frustrations about "how
much work I have ," "how
far behind I am, " and the
ever-popular, "I need more
sleep! "
I can only compare the
experience to trying to finish
a plate of food only to have
the waiter bring out another
serving. just when you're
wiping your mouth clean with the napkin, two more plates come out. And
just when you thought you couldn't eat
another crumb, the waiter decides to
bring out the main course. Not hungry?
Well , too bad, because the chef is just
getting started.
To be honest, I feel that all of the
hard work and sacrifice is worth the
effort. My experiences in the past four
months have been unlike any others.
Every day I get to ask the question ,
"How does the body work? " and every

®

day I get another answer.
My experiences go way beyond those
in the classroom, though. I will never
forget the rush of adrenaline I experienced when I made my first incision on
a cadaver, or when I was firs tasked to do
a physical examination on a patient.

new cases, and how we should learn
from the cases we have seen in the past.
Most important, we are beginning to
learn how to feel like doctors: how,
when we are presented with a new case,
we realize that this isn't simply patient
#6578463, but rather Mr. Thomas
O'Donnell who lives around the corner,
has a wife and three children, and one
day hopes to retire to Florida.
The knowledge and information I
will have gained from my years at UB
will be with me for the rest of my life,
and will allow me to carry on a tradition
of treating those who are ill, and protecting those who are not.
It is a dedication that will allow me to
realize my noble thoughts of what a
career in medicine should be.
In each issue, Buffalo Physician invites a
medical student to write a column about
a topic of his or her own choice. A member of the Class of 2000, Christopher].
DiMaio is in the middle of his first year of
medical school.

It is exciting to know that this is
only the beginning of my medical
career, and that a lifetime of similar
experiences awaits me.
I stated my idealistic views of
medicine in my application essay: "I
truly enjoy helping people, and
would like to have a career that allows me to make a difference in the
lives of those who seek it." Today,
my visions are being realized.
We are learning how to think like
physicians, how we should approach

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Phys

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ician

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Orchard Park, NY 1412 7

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A non-profit University program for students, faculty &amp; staff
The Commons • North Campus • (716) 645· 3554 • Fax: 645-3&amp;84

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�Aman who touched aenerations of students
JACK RICHERT , ASSOC IATE DEAN FOR ALUMN I AFFAIRS , RETIRES

ack Richert left many in the UB community with fond memories when he retired Nov. l from his position as associate dean
for alumni affairs. It's no wonder, because he has touched the
lives of hundreds of students- doing everything from helping
them finance their education to keeping in touch after graduation.
"I've met wonderful people in all my sions, student affairs , curriculum, medidifferentpositionsatUB," he says. "Now, cal school publications, and financial
I can go to any major city and look in the aid. He also served as coordinator of
Medical Alumni Directory and find post-graduate advisement and director
people I know. It's a great feeling ."
of the U.S. Foreign Medical Graduate
He first came to UB to earn a master's program. In the latter capacity, he won
in counseling psychology and a doctor- a $226,000 grant from the U.S . Departate in academic administration. The ment of Health, Education, and Welfare
medical school hired him in 1970 as to create a pilot program for these transfer students.
registrar and assistant to the dean.
Former associate dean Leonard Katz,
It was a time of rapid transitions. The
dean who had hired him, Leroy A. Pesch, M.D., worked with Richert to bring stuM.D., left in 1971. Clyde L Randall, dent affairs and curriculum together in
M.D., and F. CarterPannill, M.D. , served the new Office of Medical Education in
as acting deans in quick succession. It 1975. "jack took the lead in student
affairs ," Katz rewasnotuntil1975,
members . "He
with the arrival of
was also extrajohn. P. Naughton,
" IT'S BEEN GREAT TO SEE
ordinary at arM.D ., that the
SO MANY STUDENTS WHO
school had a perranging events .
CAME INTO MY OFFICE ON
manent dean.
For example, at
Naughton credgraduation he
THE FIRST DAY OF CLASS
its Richert with
added color with
GROW AND MATURE AND BE
helping to shore up
a huge UB banthe administration
ner , arranged for
SUCCESSFUL ."
music, and added
during this period.
other touches to
"It was a very tough
make ita wonderfew years, and jack
was one of three
ful pageant and a
people who served as the 'glue' to hold great celebration."
He took over the alumni affairs office
services together for the students," he
in 1984, and soon became associate dean
says.
In 1972, he was promoted to assis- and director of medical alumni affairs.
tant dean. At various times in the folHe has had a profound impact on the
lowing years , he led the offices of admis- Medical Alumni Association. When he

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first became involved with the group , it
sponsored only a few activities a year.
I oday, as a result of innovations he
introduced or facilitated , it is active yearround, offering events, lectures, awards ,
and educational programs for alumni
and current students.
He also helped expand the annual
Spring Clinical Day program into an
entire reunion weekend. The new Distinguished Alumni Awards and Alumni
Achievement Awards recognize outstanding accomplishment. Receptions
at national medical meetings make UB
alumni feel welcome everywhere.
The Medical Alumni Association has
also become much more active in student life. The association donated money
to furnish the medical student lounge,
and it participates in student and resident orientations. It also sponsors scholarships, student travel to scientific meetings, and travel to work in developing
countries. The association's Community Physician Program invites doctors
to give luncheon talks to medical students about career choices, types of practice, and lifestyles.
Richert also chaired the Buffalo Physician editorial board, where he helped the
dean choose board members that represented the entire UB community, and
was sensitive to readers' desires about the
look of the magazine , according to fellow
board member Bradley Truax, M.D. '74.
"jack wanted to make this magazine
something that the alumni would enjoy
and look forward to getting rather than just
throw in the wastebasket," Truax says.
One of Richert's accomplishments
was the creation of the james Platt White
Society, which honors alumni who make
annual gifts to the school of $1 ,000 or
more. Philanthropy was not the only

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goal of the organization.
"My goal in creating the society was
to help our alumni reconnect with UB ,"
he explains. "There had been something
of a breach between the people who
graduated from the private University of
Buffalo and those who graduated from
the public University at Buffalo (after
the 1962 merger of the university with
the SUNY system). We had graduates
who lived nearby and had never been
back to the school. We needed to bring
them back, reconnect them with the
school, and show them that they were
still part of our community."
"None of these good ideas would
have come to fruition without jack,"
says alumni association past president
Margaret Paroski, M.D. '80, who met
Richert when she was a student and he
was assistant dean for student affairs.
"He has a real knack for persuading
people to participate, take on responsibilities, and get things done, and he's
always understood how important
volunteerism is to the school and to
medical teaching in general. "
Richert's engaging manner , good
memory for names and faces , and gift for

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building friendships have been key to his
success at UB---and will make him missed.
"I was accepted just four days before
school started, so I showed up with no
idea about where to stay," recalls jack
Coyne, M.D. '85 , Medical Alumni Association president. "jack put together a
whole list of possibilities, and found
ways for me to fund my education, too.

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He took a personal interest-it was more
than just a job. "
In retirement, Richert plans to catch
up on reading and research ("There are
a lot of libraries I have neglected for too
long! ") , get involved with volunteer
activities, work on his century-old house
in Buffalo, and spend more time with his
wife and their daughter.
"As I retire, I think what a nice time
it was. There were obviously peaks and
valleys , but I think the peaks outnumbered the valleys ," he says. "It has been
wonderful to watch the school move
into national prominence.
"I also think about the pleasure I've
had in meeting so many fine people who
have become my personal friends. And
it's been great to see so many students
who came into my office on the first day
of class grow and mature and achieve
and be successful."
Recruited by admissions director
Thomas]. Guttuso, M.D., Richert will
also serve as a volunteer member of the
medical admissions committee. And so ,
even in retirement, he will continue
making connections with new members
of the UB medical school community.+
-JESSICA

A

NCKER

�Wende W. Logan-Young, M.D. '61
FOUNDER AND DIRECTOR OF THE
ELIZABETH WENDE BREAST CLINIC
BY

ANDREW

DANZO

ack in the mid-l970s, a diagnostic radiologist had a radical
idea. Armed with emerging breakthroughs in imaging technology, Wende W Logan-Young, M.D., felt that radiologists should
move out from behind their x-ray viewboxes to play a more
central role in the fight against breast cancer.
In pursuit of this vision, Logan-Young
founded the Elizabeth Wende Breast
Clinic in Rochester, NY. Now radiologists at her clinic and similar ones in
other cities are giving women more
timely and compassionate answers to
some of their most fearful questions and
reducing the need for surgical biopsies.
"Ours was the first clinic where the
radiologist intervened and started doing more of what the surgeon did ,"

®

Logan-Young recalls. "Before, the traditional role of the radiologist was to sit
down at the end of the day and look at
the image made earlier by a technician.
There was no patient contact. "
Logan-Young named the clinic after
her mother, who taught her the kind of
compassion she tries to bring to her
own work with patients. "She was my
role model , just a fabulous person,"
Logan-Young says.

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Logan-Young has been a pioneer in
the use of a multiprocedural approach
that stresses the importance of taking a
good patient history and conducting a
thorough breast examination, in addition to utilizing ultrasound and 14-gauge
needle gun biopsies.
With her associate , Nancy Yanes
Hoffman , M.S., she published Breast
Cancer: A Practical Guide to Diagnosis in
1994. The book is to be the first ofthree
volumes; she is currently working on
the second.
"The book is a distillation of 20 years
of what worked best," Logan-Young says.
Those years represent a second, perhaps third , career for Logan-Young, who
is one of a long line of Buffalo physicians
and UB alumni. During her time at UB,
she was married to classmate] onathan
Logan, M.D. '61, and was called Wende
Logan. "It was a hell of a good school,"
Logan-Young recalls. "I still have very
good feelings about the university. "
She originally entered internal medicine. After having four children, however, she couldn't keep up with the
demands of the practice and switched to
radiology. She joined the University of
Rochester School of Medicine faculty
and got involved in testing new lowdose x-ray films. If it could be perfected,
she realized, low-dose mammography
could open new doors in breast cancer
screening and diagnosis.
She also noticed how grateful women
were when she told them their results
on the same day. "This was considered
heresy in 1975," she said. At the time,
and not uncommonly even today, radiologists were supposed to report only to
the referring physician, a protocol that
she said caused delay and anxiety. "It
sounds like a small point, but it isn't, "
she says.
She became convinced that there was
a need for radiological practices devoted
to breast cancer.
"I went around to every group in
Rochester and begged them to take me

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"O~RS~IWAS~~ili HE!!IIF.IRSli C l.!! INIC!J,,W8ERE:!!,~ili 8E

RADIOI!OGISlijiiiNliERVENED AND STARli ED)~DOING~IMORE O F.:
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loau·YOUIG,

with that concept," she says. "They all
said I was crazy. So I opened my own
office."
As she was setting up, she read an
article about using an ophthalmic ultrasound scanner for breast exams. Researchers had reported promising results with ultrasound breast imaging
since the 1950s, and by the mid-1970s
several physicians around the country
were using ultrasound for breast exams,
but there was still no commercially available machine designed explicitly for that
purpose. Logan-Young bought one of
the ophthalmic units. "At that point,"
she says, "there wasn't a radiologist in
the country who was combining ultrasound and radiology."
By bringing the best tools for breast
cancer detection- clinical examination,
ultrasound, and mammography-under
one roof, Logan-Young felt that the techniques could complement one another
to more accurately identify real cancers
and to reduce the number of surgical
biopsies on masses that proved benign.
But there were problems to be resolved with the low-dose film. LoganYoung organized national meetings on
that and related issues at Roswell Park
Cancer Institute in 1977 and 1979. "A
lot of the equipment changes that came
out resulted from those meetings," she
recalls.
Logan-Young continued publishing
her results with low-dose mammography and ultrasound. She also traveled
the country demonstrating techniques
for clinical breast cancer diagnosis. Her
practice, however, was slow to take off.
"We spent a lot of time modifying the
equipment," she says.

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IDID ."

M.D.

Eventually it paid off. The Elizabeth
Wende Breast Clinic now has a staff of
80 and sees 50,000 patients a year, some
from as far as Watertown and
Binghamton, NY. "They like the ambiance of the office and they like having
the results the same day," explains
Logan-Young, who took her current
name after remarrying six years ago.
A major part of her quest to expand
the radiologist's role was fulfilled in
1993 when she acquired the first 14gauge needle biopsy unit in western
New York. The needle biopsy technique
was developed years earlier in Sweden,
but it was only recently perfected by a
Colorado radiologist who added a new

-

needle design and computerized guidance that yielded results comparable to
surgical biopsy.
"The development of the 14-gauge
needle was the last step that the radiologist needed to prevent unnecessary surgery, to keep us from doing too many
biopsies," Logan-Young says. Nationally, she added, only one out of every
five surgical breast biopsies confirms a
cancer, while the rate for her patients is
one out of 1.3.
Equipment and technique are not the
entire equation. "This sounds real corny,
but from the beginning we tried to make
the office look more like a home than an
office," Logan-Young says. "I always
hated the sterile white jackets. We put
in antique chairs and flowered wallpaper. " Three of the 14 chapters in her
1994 book are devoted to interacting
with patients. "Once you become the
one to make the diagnosis, you do a lot
of the counseling that the surgeons
would have done." +

Grover Wende, Class of 1889
Wende Logan- Young's great-grandfather's brother wrote an
early text on dermatology

George H. Westinghouse, Class of 1896
Logan- Young's grandfather

Walter David Westinghouse, Class of 1931
George Westinghouse's son was Logan- Young's fath er

Wende Westinghouse Logan-Young, Class of 1961

Physician

Walter David Westinghouse,

Class of 1964
Her brother is a San Diego cardiologist

Andrea Westinghouse,

Class of 1989
Her sister entered medicine as a second
career and is now a pediatrician in
Eden, NY

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· ··· ·· ···· · · ····· ··· · · · ·· · · · ·· ······ · · ·· ··· ·· · · ·· · ·· ······· ·· ··· · ···· · ···· · · ·· ···· ·· · · · · ··

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DONALD R . HAULER '57 , of

Pensacola, FL, has retired from
the U.S. Navy after more than 36
years of active duty. His rank at
retirement was captain. He was
awarded the Legion of Merit at a
Washington Navy Yard retirement ceremony. He moved from
McLean, VA, to Pensacola in

In April 1997, Jason, along
with Edwin Rosinski (Ed.D. '58)
and former UB faculty members
Stephen Abrahamson and
George Miller, will be honored
by the UB medical school for
their pioneering work in medical education, which began
while they were all at UB together.

September.

1
JEROME P . KASSIRER '57 ,

of Weston, MA, was named Distinguished Internist of 1996 by
the American Society oflnternal
Medicine for contributions to
the social and economic environment of the practice of medicine. A kidney specialist at the
Tufts University School of Medicine and the New England Medical Center, Kassirer is the editor-in-chief of the New England
journal of Medicine.
HILLIARD

JASON

' 58 ,

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RICHARD H . DAFFNER '67 ,

of Pittsburgh, PA, writes: "I have
just
published my
fifth textbook, the second edition of
Imaging

Strong Memorial Hospital in
Rochester, NY. He and his wife
are both clinical professors of
family medicine at the University of Colorado School ofMedicine.Jason is also co-director of
the Center for Instructional Support and co-director for education for the Society of
Laparoendoscopic Surgeons.

®

also serves on the board of the
New York State Department of
Health's Office of Professional
Medical Conduct. He and his
wife, Sharon, have two daughters, Gretchen and Julie

1

of

Vertebral
Trauma . I am currently professor of radiologic sciences at
MCP-Hahnemann School of

Medicine at Allegheny University. I am based at Allegheny
General Hospital in Pittsburgh."

ED .D . '62, of Boulder, CO ,

and his wife, Jane Westberg,
Ph.D ., recently published their
sixth book, Fostering Learning
in Small Groups. It is part of
both the Springer Series on Medical Education and the Springer
Series on Nursing Education. Jason earned his education doctorate while completing medical school and his residency at

director of anesthesia services at
Millard Fillmore Suburban Hospital in Buffalo. He is a member
of the Millard Fillmore Health
System board of directors and
president-elect of the system's
medical staff. A UB assistant professor, he is also chair of the
school's quality assurance committee for anesthesia. Burdick

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DAVID S . KOUNTZ '85 , of
New Brunswick, NJ , has been
named associate dean for postgraduate education and chief of
the division of primary care at

UMDNJ-Robert Wood Johnson
Medical School.
PEGGY

( MOREY)

STAGER

of Cleveland Heights, OH,
writes that she and her husband,
Richard, "announce the birth of
our beautiful boy, Samuel Robert, on April 1, 1996." She is
practicing adolescent medicine
at MetroHealth Medical Center
in Cleveland.
'88 ,

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MICHAEL BARON '71 , of
Bristol, TN , writes: "I have relocated to private practice in
Bristol in pulmonary critical care
medicine. The hospital is two
and a half years old and is state
of the art, and managed care is

just beginning. I am an assistant
clinical professor of medicine at
East Tennessee State University
School of Medicine."
JAMES P . BURDICK '75 ,

of

East Amherst, NY, was installed
as president of the New York
State Society of Anesthesiologists in December. Burdick is

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U.S. ArmyinfantryinApril194l.
On Dec. 7, when the Japanese
attacked Pearl Harbor, Secrist
was on guard duty on the island
of Oahu, five miles away.
In combat duty in Europe,
Secrist was wounded in action
and received the Purple Heart.
He left the Army with the rank of
first lieutenant after five years of
service.
Secrist returned to school on
the GI Bill, earning a bachelor of
arts degree from Columbia University in 1947 and his M.D.
from UB in 1951.
Secrist made house calls to
patients all over Buffalo and developed a reputation for treating
patients regardless of their ability to pay.
A member of the Erie County
and New York State Medical
Societies and the American
Medical Association, he was
board-certified in internal medicine. He was a member of the
American College of Chest Physicians.

OBITUARY
ROBERT SECRIST '51 , clini-

cal associate professor emeritus
at the School of Medicine and
Biomedical Sciences, died Nov.
5 in his hometown of Lockport.
He was 78.
Secrist attended Cornell University for three years before
leaving to work at Bethlehem
Steel. He was drafted into the

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�BUFFALO PHYSICIAN

Non-Profit Org.
U.S. Postage
PAID
Buffalo, NY
Permit No . 311

STATE UNIVERSITY OF NEW YORK AT BUFFALO
3435 MAIN STREET
BUFFALO NEW YORK 14214

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ADDRESS CORRECTION REQUESTED

PLAN'fiNG

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TREE UNDER WHICH

Ll

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You WILL

NEVER SIT

DR. DEVILLO W. HARRINGTON, class of 1871, knew how to make his money grow. In fact, this man who in 1905 provided $5,000 through his
will for the University at Buffalo School of Medicine, is still supporting UB today through the endowment his bequest created.
THIS PERMANENT endowment in Dr. Harrington's name has grown to over $300,000 and today it supports the famous
Harrington Lecture Series, which twice a year brings distinguished scientific speakers to the School of Medicine and Biomedical Sciences.
DR. HARRINGTON'S LEGACY to UB is just one of many bequests which have established permanent and important endowed funds at
the school. They enable UB to provide scholarships to outstanding students, enhance scientific research, support excellence in teaching and
meet the ever-changing needs of the school.
YOU TOO can provide the School of Medicine with a measure of permanence through a bequest. Proper estate planning helps you
develop a smart financial plan. Acharitable bequest provides the satisfaction that comes from planting a tree under which you will never
sit, but which will bear fruit for generations to come.
FOR ACONFIDENTIAL consultation on making a bequest to the UB School of Medicine and Biomedical Sciences, or to receive
materials to share with your attorney or estate planning advisor, please contact:
STEPHEN A. ESSARY, JR.

I

Assistant Dean and Director of Development, School of Medicine and Biomedical Sciences

UNIVERSITY AT BUFFALO
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�BUFFALO PHYS I CIAN

Volume 31, Number 2
ASSOCIATE V ICE
PRESIDENT FOR
UN IVERSITY SERVICES

Dr Carole Smith Petro
DIRECTOR OF
PUBLICATIONS

Kathryn A. Sawner
EDITOR

jessica Ancker
ART DIRECTOR/DESIGNER

Alan]. Kegler
PRODUCTION MANAGER
Ann Raszmann Brown
STATE UN IVERSITY OF
NEW YORK A T BUFFAL O
SCHOOL OF MEDIC INE
AND B IOMEDICAL
SC IENCES
Dr john Wright, lntenm Dean,
V1cc President for Clinical Affcurs
EDITORIAL BOARD
Dr Bertram Portin

Dr Martin Brecher
Dr. Harold Brody
Dr. Richard L. Colhns
Dr. Jack F. Coyne
Dr. AlanJ Drinnan
Brian Duffy
Dr James Kanski
Dr Barbara MaJeroni
Dr. Ehzabeth Olmsted
Dr. Charles Paganelh
Dr. Stephen Spaulding
Dr Bradley T. Truax
Dr. Franklin Zeplowitz
TEACHING HOSPITALS AND
LIAISONS

The Buffalo General Hospital
.\1icharl Shaw
The Children's Hospttal of Buffalo
Erie County Medical Center
Mercy Hospital
Millard Fillmore Health System
Franh Sam
Niagara Falls Memorial Medtcal
Center
Roswell Park Cancer Institute
Sisters of Charity Hospital

Dear Alumni and Friends,
THIS REPRESENTS MY FIRST OPPORTL,NITY as interim dean to communicate
with you through the medium of the Buffalo Physician. During my
tenure in this position, we will be presented with opportunities to
build upon the many accomplishments fashioned in thejohn Naughton
era, but we will also need to break new ground as we address new
challenges. Managed care will, in whatever form it ultimately takes in
Western New York, require significant changes and adaptations not
only for the medical school but for the entire health-care delivery
system in the Western New York region.
Most of you are aware of the merger discussions between the
Buffalo General, Children's, and Millard Fillmore Hospitals (see the Winter 1997 Buffalo
Physician). As the reorganization unfolds, we may be presented with unique opportunities
to reconfigure our programs at these institutions and elsewhere, and, in the process,
maximize the distribution of faculty in a way that will enhance not only efficiency but also
academic creativity. There is probably no single model that will address these needs. The
process will not only be complex but likely driven by considerations beyond our control,
and, in some instances, completely unanticipated.
Provost Thomas Headrick recently circulated a major discussion document, "Planning UB's Academic Future: A Report to the UB Community," which outlines a number
of bold new considerations for the university at large. The document is actually a "work
in progress," and during the next few months, the provost and president William Greiner
will be meeting with the faculties to discuss some of the concepts and proposals contained
therein. Some of the suggestions for the medical school are new to this geographic region,
but most are being considered or implemented in many other parts of the country.
One of the most challenging ideas involves rethinking the traditional departmental
structure and possibly reorganizing at least some of the faculty around interrelated
disciplines. UB boasts 28 departments, significantly more than many other schools,
including such icons of medical progress as johns Hopkins. Whether other configurations
are right for Buffalo remains to be seen, but at the least, they merit our serious
consideration and study.
All in all, these will be challenging and exciting times. We will keep you updated
through the Bllffalo Physician and through our meetings with faculty, alumni, and friends
of the university through the months ahead .

~

W right, M.D.

lntenm Dean, School of Medicine and Biomedical Sciences
Interim Vice President for Clinical Affairs

Dennis ivtcCarthy
Veterans Affairs Western New York
Healthcare System
©The State Uniwrsity of New York
at Buffalo

Buffalo Physician is published
quarterly by the State Unl\-ersny of
New York at Buffalo School of
Medtcine and Biomedical Sciences
and the Office of Puhhcations. It ts
sent, free of charge. to alumni, faculty,
students, residents and friends. The
staff reserves the right to edn all copy
and subm&lt;ssions accepted for
publication.
Address questtons, comments and
submisstons to: The Ednor, Buffalo
Physician, State Lmversny of New
York at Buffalo, Office of Publtcations. 136 Crofts Hall, Buffalo.
N) H260

Send address changes to: Buffalo
Physician, H6 CFS '\ddttion, 34 35
Main Street. Buffalo NY l42H

Dear Fellow Alumni,
As THE SNOW MELTS and the crocuses try to bloom, we find ourselves
with new leadership at UB. A towering, gentle man, john Wright,
M.D., serves as the interim dean of the School of Medicine and
Biomedical Sciences. He is not only blessed with administrative skills,
but is also an outstanding teacher. I met him when I was a second-year
medical student, and found that he was one of the few teachers who
could make medicine come alive. Like many in our class, I was
rejuvenated. I wanted to get out there and cure the world, or at least,
learn as much as possible now so we could someday make a difference. john generated this enthusiasm in many of us.
It's because of role models such as john that UB offers outstanding programs like the
Master Clinical Teaching Fellowship, developed by Diane G. Schwartz, Sheila Brodnick,
and Richard Sarkin , M.D. As a graduate of this fellowship program, I am excited to share
it with you in the pages of Buffalo Physician. l found it an immensely valuable experience
for teaching students in my clinical practice.
And thank you, Dr. Wright, for your inspiration as a teacher, researcher, and
individual. We have exciting, challenging times before us, and no one better to lead us.
Sincerely,

~y~DC'~ /'?~
President Med1ca/ Alumn1 Assooat:10n

�VOLUME

31 ,

NUMBER

2

SPRING

8

Teaching on the Fly:
US HELPS DOCTORS

COMBINE TEACHING WITH

14

OB-GYN today
PHYLLIS LEPPERT ,
M . D .,

R . N. ,

PH . D ., IS THE

PRACTICE

DEPARTMENT'S INTERDISCI-

by Nicole Peradotto

PLINARY NEW CHAIR

photos by Frank Cesario

by Jessica Ancker

18

97

Amedical mission
to Kathmandu
by Donald P. Copley, M.D. '70

08-GYN yesterday
RANDALL AND WINKLER

REUNITED A

DI V IDED

DEPARTMENT

New faculty

by Ronald E. Batt, M.D. '58

VICTOR .JAMES
HERNANDEZ ,

PH.D .,

AND MARIA LAURA

A V ANTAGGIATI , M.D.

Research news
TOSHIBA FOUNDS

Astudent's perspective:

STROKE RESEARCH

MEDICINE IS A

CENTER.

MILD CONCUS -

OF POWER

SIONS CAUSE LASTING

BY MICHAEL MERRILL ,

PROBLEMS . SURGERY

REMAINS AN OPTION FOR

GAME

CLASS OF

Medical school

Alumni

WPW SYNDROME.
PARENTS '

1 997

COUNCIL
FRANKLYN KNOX

SUPPORTS STUDENTS .

Hospital news
ROSWELL PARK FACES
CHANGE.

PAROSKI BECOMES

ECMC MEDICAL DIRECTOR .

HCP REORGANIZES.

COMBINES RESEARCH
BUCK AND WRIGHT
WITH LEADERSHIP.
RECEIVE HONORS. TWO
HARRINGTON LECTURE
ALUMNI GIFTS.

NEW
FOCUSES ON

DEGREE OFFERED.

MEL
PHYSIOLOGY .

DIEDRICK DIES .

Classnotes

�World-class stroke research center established at UB
with $3.6 million gift of Toshiba imaging equipment
esearchers are getting down to
work in a new world-class stroke
research center established at UB
with a $3.6 million gift of equipment and services from Toshiba
America Medical Systems.
Toshiba has donated its most advanced cerebral angiography equipment to help researchers study stroke
and perfect new minimally invasive
neurovascular surgery techniques.
"What's exciting about this center is
that it provides researchers with the
same kind of super-high-tech equipment that we're using in the hospitals,"
says L. Nelson Hopkins, M.D., director
of the new center and chair of UB's
Department of Neurosurgery. "So the
research we're doing is only months
away from use on patients-not years."
Phase one of the project was completed in December with the installation of one of Toshiba's top-of-the-line
angiographic x-ray machines in the
center on the fourth floor of UB's Biomedical Research Building. The
Toshiba machine can show blood vessels as small as a half a millimeter
across, and can make video images at a
rate of thirty frames per second (about
the same speed as a standard video
camera).
In phase two, Toshiba will donate a
model of its next generation of
angiographic equipment, which will
have three-dimensional capabilities
and be able to take even faster images.
"We'll have the first one in the world,"
says Hopkins. That means that UB researchers will be developing the techniques that will be used by physicians
around the globe.

Such equipment is necessary for some of the newest endovascular surgery
techniques, which depend
on maneuvering flexible
microcatheters through the
maze of cerebral blood
vessels.
The donated angiographic equipment includes positioners and
focus tubes, cameras, digital video recorders and interfaces, generators, computer software, and workstations.
"Minimally invasive procedures will dominate surgery in the 21st century,"
Hopkins says.
"Tomorrow's neurovascular technology will be developed, tested, and perfected here. We know of no
other research center with
comparable equipment and
capabilities."
Installation of the equipment was
aided by a grant from the Wendt Foundation, which helped offset the cost of
essential structural alterations. Another
grant from an anonymous donor will
help cover operating expenses.
A pioneer in endovascular surgery
and chief of neurosurgery for the
Millard Fillmore Health System,
Hopkins was instrumental in developing the new partnership with Toshiba.
He was recently a lead researcher in
clinical trials of the Guglielmi Detachable Coil, the first product to receive
approval from the U.S. Food and Drug

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Administration for treating intracranial aneurysms considered too high
risk for traditional surgery.
UB'sstroke researchers at the Toshiba
center will have three priorities. One,
under the guidance of radiologist
Stephen Rudin, Ph.D., is to achieve
even better imaging with the lowest
possible x-ray dosage. Rudin's new procedures should increase resolution capabilities from half a millimeter to a
tenth of a millimeter, Hopkins says.
In an unusual collaboration, Barry
Lieber, Ph.D., an aerospace engineer
who specializes in the dynamics of air

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flow, is working with neurosurgeon
Ajay Wakhloo, M.D. , Ph.D. The two
scientists are combining their expertise to investigate the dynamics of blood
flow, using full-scale models of cerebral blood vessels.
Finally, Lee Guterman, M.D., Ph.D.,
is researching new techniques and de-

viding funding to support graduate student stipends and an exchange program between japanese and American
researchers.
"Further, since any area of the body
can be accessed through the vascular
system, other departments, such as cardiology, surgery, and radiology, will have
the option of conducting
studies using the Toshiba
angiographic equipment,"
u.w~ ..... . , . ....................
Hopkins says.
In addition to research,
the center will provide
unique educational opportunities.
"We currently offer
working
courses
in
endovascular techniques
for treatment of experimental aneurysms. The Toshiba
Stroke Research Center will
enable us to expand and
diversify our offerings, attracting course participants
from around the globe,"
Hopkins says. "The flow of
personnel and information
between the center and
other international research
centers in
the U.S. and
Asia will offer unique
educational opportunities to UB students and
faculty and the Western
vices to treat and prevent stroke, espe- New York research comcially minimally invasive endovascular munity at large."
Toshiba selected UB
surgical procedures. Techniques used
by UB 's neurosurgeons include because of "the clinical
microcatheter injection of thrombolytic expertise, commitment,
drugs to break up clots and stents to and research" of Hopprovide permanent support for nar- kins and his colleagues,
says Jeffrey T. Dillon,
rowed vessels.
The Toshiba research facility will sales manager with
also be used by researchers developing Toshiba America Medi new treatments for conditions other cal Systems.
Toshiba
America
than stroke, and will serve as an educaMedical
Systems,
based
tional center for students from UB and
around the globe. Toshiba is also pro- in Tustin, California, is

. _........"

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a subsidiary of the international Toshiba
Corp., one of the world's largest manufacturers of electrical and electronic
equipment, with annual sales of more
than $48 billion. Toshiba America Medical Systems' line of medical imaging
systems includes diagnostic x-ray, xray computed tomography, diagnostic
ultrasound, and magnetic resonance imaging.
"This new stroke research center will
capitalize on all the best strengths of
UB's School of Medicine and Biomedical Sciences-pioneering research, outstanding clinical care, and exceptional
teaching," says UB president William
R. Greiner.
"We are absolutely delighted to have
Toshiba as a partner in this center.
With an international corporate leader
like Toshiba generously supporting the
work of a first-class researcher and surgeon like Dr. Hopkins, we think that's
a recipe for success. Most importantly,
the creation of this center promises
better health and fuller recovery for
millions of people. And we think that's
the real success." +
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LOIS BAKER AND JESSICA ANCKER

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Surgery remains an option for
some with WPW syndrome
hree catheter ablations failed to
correct Clayton Broussard's WolffParkinson-White syndrome, and
he continued to suffer debilitating attacks of tachycardia.
So his family brought fourteenyear-old Clayton from Louisiana to Buffalo where he could be operated on by
Gerard M. Guiraudon, M.D., a pioneer
in the treatment of cardiac arrhythmias
and one of the few surgeons in the world
who has remained an expert in epicardial surgery for Wolff-Parkinson-White
syndrome. The operation was a complete success.
"Even the best horse-drawn wagon
had to be replaced with a motor car,"
Guiraudon says. "But once in a while,
the horse still works better."
In Guiraudon's metaphor, his epicardial surgical approach to arrhythmia is
the horse cart, while the newer catheter
ablation techniques are the motor cars.
Surgery for Wolff-Parkinson-White
syndrome was pioneered in 1968. But in
the early 1980s, while at the University
ofWestern Ontario in London, Ontario,

way for a change in technology. By relying on Guiraudon's techniques to pinpoint the accessory pathways, surgeons
were able to use catheter radio frequency
ablation to fix most Wolff-ParkinsonWhite cases. Guiraudon himself helped
train the new generation of catheter
surgeons.
Since 1990, catheter ablation has become the method of choice for treating
Wolff-Parkinson-White syndrome. "I
went from 120 of these patients a year to
just five or ten," Guiraudon says. Today, he performs the surgery on patients
like Clayton, who have undergone catheter ablations without success, or on
patients who are scheduled to undergo
open-heart surgery for other reasons.
In a 1994 review article in the Annals
of Thoracic Surgery, Guiraudon lightGuiraudon led an international team of
heartedly focused a "retrospectroscope"
surgeons in developing safer epicardial
on the surgical treatment of Wolffsurgical techniques. Avoiding cardioParkinson-White syndrome. He conpulmonary bypass, they worked on the
cluded that "a large body of scientific
beating heart using surgical dissection,
knowledge and skill was brought to
cryoablation, or lasers.
light by this experience and, of even
For nearly ten years, Guiraudon's apmore importance, passed on for best use
proach was the first choice for Wolffto the catheter surgeons."
Parkinson-White patients. "Everybody
But Guiraudon is not ready to retire
visited this man and learned from him,
yet. Born and trained in France, he was
and everybody sent patients to see him,"
a professor of surgery in Paris before
says Tomas Salerno, M.D., the director
accepting a position at the University of
of cardiothoracic surgery at the Buffalo
Western Ontario and University HospiGeneral Hospital. "Getting Gerard
tal in London, Ontario, at age fifty. Now,
Guiraudon to come to Buffalo was like
at sixty-five, he has become an immiputting a little hook in the ocean and
grant again, moving to Buffalo to becatching a huge fish."
An accomplished valve surgeon who come UB 's associate chief of
developed what has become the stan- cardiothoracic surgery and the chief of
dard approach to the mitral valve, cardiovascular and thoracic surgery at
Guiraudon has also authored classic pa- Millard Fillmore Health System. His wife,
pers on cardiac arrhythmias that are Corette M. Guiraudon, M.D. , remains
referenced in such texts as Harrison's in London, Ontario, as the hospital's
chief of pathology.
Principles of Internal Medicine.
"If you move, you do better," he says.
Guiraudon and his colleagues also
"You
look at things in a new way, not in
did extensive work in mapping the aca
preconceived
way. I moved to London
cessory pathways that cause Wolffbecause
I
thought
I could have a fruitful
Parkinson-White syndrome. "Our goal
collaboration
with
my colleagues there,
was not just to do the surgery, but also
and I did. Now, I hope I can do someto understand the pathophysiology."
That new understanding paved the thing new here." +
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Mild concussions can cause
lasting abnormalities in brain
esearchers at UB have shown that
a concussion results in abnormal
brain activity that can last for
months. This activity correlates
with patient complaints of physical and emotional discomfort early
on, and with various cognitive impairments later, the researchers found.
Richard Linn, Ph.D., assistant professor of rehabilitation medicine, led a
multidisciplinary research team which
uncovered the abnormal brain activity
in a small group of patients with recent
concussions, using PET scans taken at
the PET Center in the Buffalo Veterans
Affairs medical center. The abnormalities were invisible to MRI.
"In the first few weeks post-injury,
some of these patients may experience
headache, irritability, dizziness, or fuzzy
thinking," Linn says. "They may have
an MRI scan, which typically shows no
abnormalities. Many may come away
still feeling that their thinking isn't right,
but they don't know why.
"We now are able to show that these
symptoms are related to a definite
change in brain activity, and that these
patients are not merely imagining their
symptoms. The abnormalities in the
brain reflected how well patients performed on cognitive tests. The greater
the abnormality, the worse the patient's
performance."
Linn, program director of the UB T raumatic Brain Injury Rehabilitation System, is one of only a few researchers in
the country who are using PET to study
mild traumatic brain injury. Linn's research is funded by the National Institute of Disability and Rehabilitation Research.
PET scans were administered to six
victims of concussion two to three weeks
after the injury and again three to four
months later. The scans revealed small

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but significant areas of increased glucose metabolism in the anterior cingulate, more pronounced in the right hemisphere than the left.
All the patients had had normal MRis
and showed few signs of injury.
The increased use of glucose may be a
sign that the cells are repairing themselves after injury, or that their ability to
function is diminished and they need
more energy to perform the same work,
Linn says.
In the early stages after injury, this
abnormal activity correlated with patient complaints, such as headache, irritability, anxiety, depression, dizziness,
and lack of concentration-symptoms
collectively dubbed post-concussive
syndrome.

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The studies showed that after three to
four months, the areas of abnormal activity had enlarged somewhat and were
correlated with impaired attention span,
verbal memory, motor function, and
information processing, but not with
post-concussion symptoms.
"Patients need to know they aren't
going crazy, and that what they are
experiencing may be a normal part of
the recovery process," says Linn, who is
now recruiting patients for a larger study.
According to Linn, the only treatment
for mild traumatic brain injury is patience. "People just have to wait it out.
More than 50 percent of them are back
to normal by six months; more than 95
percent are fully recovered in a year." +
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~

Roswell Park Cancer Institute faces change
BY

ANDREW

DANZO

s managed care's relentless expansion forces medical institutions to behave more like
businesses, adaptation has become the watchword. At Buffalo's venerable Roswell
Park Cancer Institute, however, change doesn't come easily.
The 99-year-old institute is part of state government, and that, according to many people
inside and outside the institution, has hobbled its ability to compete in the new healthcare marketplace.
New York State officials have proposed
spinning Roswell Park
off as an independent
non-profit entity. The
plan is greeted enthusiastically by those who
believe the institution
will benefit from increased flexibility, but
it has others worried
that Roswell Park may
jeopardize its tradition
of groundbreaking
cancer research in its rush to become
self-supporting.
Robert Hinckley, public affairs director for the state Health Department,
points out that being a part of the state
hampers Roswell Park in some of its
everyday activities.
"They can't develop networks, partnerships, mergers, et cetera, and react
quickly to this changing health care
environment," Hinkley says. "They can't
do a lot of things that the Buffalo General Hospital can do. To get a $5,000
contract approved they have to go
through this department, the Division
ofBudget, and the Comptroller's Office.

0

CHANGE IF IT IS TO

Buffalo General doesn't have to do that." Anderson Cancer Center at the UniverGov. George Pataki this year proposed sity of Texas in Houston. For example,
that Roswell Park be allowed to change he would like greater flexibility to creits governance structure, possibly be- ate new types of positions. "We need
coming a not-for-profit enterprise or af- managedcare specialists and case manfiliating with another health-care institu- agers," he explains. "The current systion. Approval is required from the state tem takes an enormous amount of time
Legislature, and details remain to be and effort when we need to move
worked out. One strong supporter of the quickly. This is an institution that needs
plan is the institute's new president, David to reinvent itself."
C. Hohn, M.D. He succeeds Thomas B.
But Pataki's proposal for a governance
Tomasi, M.D., who left last year after change has been greeted skeptically by
running the institute for a decade.
unions. "We think some of the cost
"I think Roswell must change if it is to issues can be addressed within the conthrive and survive," says Hohn, who text of a public institution," says Richarrived in February from the M. D. ard E. Casagrande, executive director of
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the Public Employees Federation, which
represents 845 physicians, research scientists, nurses, and technicians at
Roswell. "We see privatization as being
really radical surgery. I think the primary gain, when you cut through the
fluff and the sweet talk, is that they
think that the public employees make
too much."
Hinckley says the plan is not an attempt to void state union contracts.
"We've told them that we will abide by
the collective bargaining agreements
they have," he says. "Certainly, because
of their expertise, any not-for-profit
would need the vast majority of the
employees."
Some staff members worry nevertheless that Roswell could lose itself in the
transition. "Roswell is not simply another hospital," says a senior scientist
who asked not to be named. Without
financial support from the state, he fears
that Roswell will begin to lose research
grants and become trapped in a downward spiral.
"Roswell was never supposed to compete with a normal hospital, because it
doesn't offer the same product," the
researcher says. "You don't go to Roswell
Park to get the same care as at Buffalo
General. You go to Roswell Park because that's where we're developing new
treatments that no one in their right
mind is paying for."
Through the Graduate Medical Dental Education Consortium, Roswell Park
trains 26 UB residents. In its capacity as
a UB graduate division, the institute also
trains about 300 graduate students. The
25-acre Roswell Park campus is in the
midst of a $245 million construction
project.
The institute's fortunes, however, have
been slipping in the increasingly competitive health-care industry. Despite
its National Cancer Institute designation as one of only 28 comprehensive
cancer centers in the nation, Roswell
has seen insurers steer many patients

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elsewhere, and Buffalo General now
handles a greater portion of the region's
cancer cases. The institute's deficit is
put at about $70 million, and it has been
unable to join hospital systems being
formed by Buffalo General, Millard
Fillmore Health System, and other Western New York institutions.
For his part, Hohn says he is dedicated to maintaining Roswell's status as
a premier center for research and teaching, as well as for treatment and prevention. "I think acquisition is unlikely and
probably not desirable," he adds. "This
is not about unloading Roswell on someone else. I would not have come here if
that was the intent. It is about the ability
to affiliate, because health care is organizing into networks and systems. But
the exact governance that would be put
into effect has not been established."
The governor's proposal also includes
an additional $70 million for Roswell
Park in each of the next three years.
Some of that would be used to begin a
20-year plan to repay the state for the
institute's deficit.
Roswell Park's new president expects
to become a familiar face in Albany over
the coming months. ''I'm absolutely committed to building the case for ongoing
state support for education and research," Hohn says. He also plans to
step up the pursuit of grants and philanthropic support.
"My vision of Roswell is for a growing
and thriving institution," he adds. "I
think we're really talking about building a brighter future." +

HealthCarePlan reorganizes
ealthCarePlan, Western New
York's oldest HMO , is moving
away from its roots as a staffmodel HMO.
The 90 doctors who work for
HealthCarePlan are leaving the
HMO to form their own group, Medi-

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cal Partners of Western New York,
which will continue to care for HCP's
patients as a contractor. Patients will
notice little or no change.
The decision has been described by
both sides as mutually amicable. Richard Battaglia, M.D., who will become
medical director of Medical Partners,
said the move will benefit the physicians because they will be able to accept payment from other insurers as
well as from HCP.
Medical Partners, which will be
largely primary care doctors, is also
exploring the possibility of merging
with practices that contain more specialists, including the Buffalo Medical
Group, he said. +

UB alum appointed ECMC
medical director
argaret Paroski M.D . '80, of
Buffalo, NY, has been appointed
medical director of Erie County
Medical Center.
In this position, she oversees
the medical operations of the
ECMC Healthcare Network.
The network includes the medical
center, the Erie County Home, and a
growing group of community health
centers.
Paroski is the
former clinical
director
of
ECMCs Department of Neurology.
She is also a
past president of
the UB Medical
Alumni Association.
In addition to
maintaining her Margaret Paroski, M.D.
medical practice
and her administrative roles, she continues to be an active researcher. +

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�BY

NICOLE

PERADOTTO

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In
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UB HELPS
DOCTORS COMBINE
TEACHING WITH
PRACTICE

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"Teaching is about being a good role model.
Inspiring people is a part of teaching."

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- Pediatrician Richard Sarkin, M.D.

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Spring

1997

�IN THE MIDDLE AGES, teachers were known as "doctors ," a
word derived from the Latin verb docere, to teach.
By definition, then, a doctor is a teacher. And at clinics, offices, and hospitals
around the world, many doctors take that definition very seriously

B

Take, for example, Kerryann Broderick, M.D., site residency director for emergency medicine at Erie County
Medical Center. At 9:00a.m. one weekday, Broderick and
fourth-year UB medical student jacqueline Dombrowski
interpret a patient's chest x-rays for signs of tuberculosis. At

and Biomedical Sciences.
Ask students why, in addition to clinical courses, they
shadow physicians in their scant free time , and they respond
that there's no such thing as too much clinical exposure.
Such learning allows them to leave the lecture hall, to leap

9:30, Broderick asks Dombrowski to help document a ninetynine-year-old woman's death, and then ushers her off to the
quiet room to watch a resident break the news to the family .
Half an hour later, the physician offers the student tips on
how to debride a chemical burn and how to present a
diabetic patient to the patient's primary care physician.
Then Broderick listens to Dombrowski's presentation of a
man complaining of intense pain in his left foot. Upon seeing
the patient herself, Broderick congratulates her student for
correctly diagnosing that the man did not in fact suffer from
an infected toe naiL
Welcome to "Teaching on the Fly 101 "-clinical instruction. Physicians find many ways of folding the education of
students into their own practice of medicine. Under a
physician's supervision, students can take histories , diagnose, and even treat patients. Clinical instruction represents
more than half of the coursework at UB's School of Medicine

from the hypothetical textbook case to a patient on a gurney.
For many students, clinical experience helps determine
specialties and build confidence.
For the preceptors-many of whom volunteer their timethe benefits of teaching may not seem so obvious. Teaching
takes time. Balancing patient care with student instruction
can be exhausting. Being a preceptor can be demanding in
other ways , too; students often expect teachers to serve as
career counselors and personal advisors in addition to
fulfilling their role as instructors.
Yet those who teach insist that its rewards offset its
demands. Teaching is as enlightening an experience for
them as it is for their charges, and it makes them finer
physicians.
"Students require a lot of energy," says Broderick, assistant professor of emergency medicine. "They ask tons of
questions and need a lot of supervision, especially early on.

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�"More and more schools have been expanding their
But I get challenged by them, and they're just so eager to learn
clinical medicine offerings over the last couple of years
and do small things.
"They keep me really fresh, particularly at the basic because it is necessary," explains Dennis Nadler, M.D.,
science level. They'll ofassistant professor of
ten ask, 'Why did you do
clinical pediatrics and
something that way?'
associate dean at the
"Spending a lot of time in lecture halls and
That makes me question
medical school. "Spendlaboratories can bring students down. Its
why I chose that way and
ing a lotoftimein lecture
wonder, 'Is there another
halls and laboratories can
helpful for them to have (clinical)
way? Is there a better
bring students down. It's
way?'"
helpful for them to have
exposure, to see whats coming down the
In the emergency dethis exposure , to see
partment, where time is
what's coming down the
line and to maintain their enthusiasm. "
of the essence and
line and to maintain their
unpredictability is the
- UB Associate Dean Dennis Nadler, M.D.
enthusiasm."
norm, Broderick is well
At the clinical level, UB
aware that persistent incounts 1,512 volunteer

•
quisitiveness can be too much of a good thing. In such
instances she arms herself with options for students who
threaten to slow the pace of operations.
"Sometimes I try to sneak in to see a patient before a
student does. Then I can come out and set things up that
need to be done, like drawing blood. Sometimes, if I don't
think they're quite ready to do a certain procedure, I say,
'You have to back off and watch what I do,' or I give them less
acute tasks to perform."
"You really have to learn how to switch gears very
quickly. You have to assess a student's level, get to it, and
then explain things at that level."

faculty and 807 geographic, full-time faculty. Ehsan Afshani,
M.D., clinical associate professor of radiology, falls intaA..he
second category.In 1990 and again in 1996, Afshani received
a louis A. and Ruth Siegel Teaching Award, an honor based
on student nominations.
Among the teaching duties Afshani considers most important is fostering critical thought. It's a skill that some students, dazzled by high-tech diagnostic tools and insecure of
their own abilities, have a tendency to neglect.
"In medicine you don't deal with x-rays alone , and
students in radiology must be reminded of that. Sometimes students prefer just looking at x-rays and taking
tests instead of what's so important: Talking with patients.
Whenever they want to order a test, I say, 'Is it worth doing
because it's going to help you come up with a diagnosisor because protocol tells you to do it? '"
It's not just that Afshani appreciates the Socratic method.
He wants his students to appreciate health-care costs, too.

Clinical experience in the curriculum
New to UB's curriculum this year is a two-year introductory clinical block that begins during the freshman year.
Among the skills taught are history taking, diagnosing,
cardiopulmonary recuscitation, and infection control.

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�and throat. He organized his fourth-year schedule with a
rotation in pediatrics at year's end, recognizing that it would
provide him with ample opportunity to examine a host of
sore throats, runny noses, and aching ears.
"That four-week experience absolutely turned my life
around. I had the most wonderful teacher (Mary Cruise,
M.D., who is now retired), and she helped me realize that
pediatrics was for me. There is no question in my mind
that she, more than anybody else, was responsible for my
decision. "

And that's something preceptors must consider, as well,
Nadler emphasizes .
"Students take extra time, and at teaching sites, extra
time is provided. But managed-care organizations don't
want to pay a physician to see twenty patients a day when
he or she can see thirty patients a day for the same amount
of money. This is something we have to think about, and
we'll be discussing it more in the future . And it's not just
managed care. If there's a guy in a solo practice, his entire
base is the number of patients he sees. But I don't know
anyone who has made a conscious decision not to teach
because of economics."
That's often the case because physicians remember the
teachers who nurtured them when they were students and
residents, and they want to continue the tradition.
When he was a medical student in 1970, Nadler planned
to do a residency in surgery followed by one in ear, nose,

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Consider you r goals and
objectives, and communicate
them to your learner.

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Discover enthusiasm for
your subject and for you r
lea rners.

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Take you r teach ing and their
learning seri ously- plan,
teach, reflect.

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Get to know your learners
as people, not just as
learners.

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Promote self-directed
learning.
Provide frequent, timely,
constructive feedback.

Consider how you know if your
learners are learn ing what you
want them to be learning.
Make your teaching and their
learning fun .

From "Sharpeni ng the Saw:

Improving Preceptor Teac hing

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Make you r learners as active
as possible.

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Becoming a good teacher
Not every doctor is a good teacher.
Even the best doctors can make simple mistakes when
they start teaching. They may be disorganized. They may fail
to give students feedback, or be unable to give clear descriptions of protocols and procedures. Some may take students'

physician

Skills," a handout written by

Admit your own limitations.
Re-learn how to say, " I
don 't know."

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Richard Sarkin, M.D.

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�"The more approachable you are as a teacher, the more
abilities for granted; others may underestimate students.
comfortable
students will be around you, and that's a positive
As one doctor puts it, "There are a number of physicians
them to learn in," says Sarkin. "I think there's
atmosphere
for
I would want to treat my kid-but not to teach him. " In
a very thin line beother words, even a
tween a demanding
physician esteemed
teacher and a teacher
by colleagues and
"You really have to learn how to switch
who intimidates, and
liked by patients
the latter model is
may lack essential
gears very quickly. You have to assess a
pervasive in medical
teaching skills.
schools.
UB has initiated
student~
level,
get
to
it,
and
then
explain
"Another problem
several programs
through the Priis that most people
mary Care Resource
think that when
things at that level."
Center to help docthey' re teaching ,
tors become better
they're telling some- Emergency physician Kerryann Broderick, M.D.
teachers. The cenbody something. But
ter, directed by Riit's questionable

chard Sarkin, M.D. , is a joint program of the Departments of
Internal Medicine, Family Medicine, Pediatrics, Social and
Preventive Medicine, and Obstetrics/Gynecology.
One of the center's programs, the Master Clinical
Teaching Fellowships, offers selected community physicians a stipend to attend an eight-month workshop series
on clinical teaching.
A second, the Teaching Effectiveness Program, offers
faculty a choice of workshops on specific practical questions, such as, How does a preceptor handle a bright but
condescending student? What's the best way to introduce
students to patients? How can a preceptor criticize students
without disheartening them?
Sarkin, a clinical associate professor of pediatrics, teaches
many of the workshops. A movie buff, he shows clips from
such films as Footloose, Mr. Holland's Opus, and The Paper
Chase when discussing the qualities of a capable teacher.

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whether the person they're talking to is learning or not.
We're trying to expand the whole notion that teaching is
providing information. Teaching is about being a good role
model. Inspiring people is a part of teaching. So is promoting self-directed learning, where students aren't so much
provided information but motivated to learn on their own. "
At the Children's Hospital Ambulatory Pediatric Clinic,
doctors wear animal toys wrapped around stethoscopes,
and patients stop by a drawer filled with stickers at the end
of their visit. Here, Sarkin practices what he preaches.
One afternoon he discusses a hypothetical patient suffering from persistent headaches with a handful of residents
and a third-year medical student. Then the group turns
their attention to a dozen or so real patients- youngsters
sitting in the waiting room suffering from the flu , runny
noses, or other winter ailments.
After seeing his first patient of the day, medical student

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�Anand Singh talks with Sarkin.
"His mother says he has cold symptoms that are
coming and going. The cough is not producing anything,
and he's tugging on his ears. I tried looking in his ears,
but he started crying."
"So, he looked sick and uncooperative?"
"Yeah. He stuck his fingers in his ears when I tried to
look in them."
"Did you make him say 'Ah ?"'
"Well, by that time he was crying."
"That's an 'Ah,' isn't it?"
Doctor and student discuss potential diagnoses and
treatments before they walk down the brightly lit hall to
room 7. There, a boy no taller than a kitchen stool sits
glumly in his mother's lap. As Sarkin turns to address the
toddler, his voice changes. Suddenly the fast-talking pediatrician paces his words extra slowly. His tone mellows; the

pitch of his voice rises. He sounds like a narrator for a
children's movie.
"Are these your hands, Taylor? Oh, these are very nice
hands. Can the nice doctor see your tummy?"
At first the two-year-old doesn't protest when Sarkin
pulls up his sweatshirt. When he starts whining, Sarkin
encourages him to touch the stethoscope. This holds the
boy's interest for a few seconds.
Now it's time for the ears.
"If I promise not to hurt your ears, can I look at them?"
Taylor shakes his head.
"OK," Sarkin says as he gently tugs the boy's fingers
from his ears, peers inside them, and spots signs of a
middle-ear infection.
Singh raises his eyebrows and grins.
He has learned a skill that no textbook-no matter how
comprehensive-can teach. +

UB provides support for clinical teaching
Because more medical education today takes place in community physicians' offices, UB is placing a greater emphasis on
helping doctors become good teachers.
UB's Primary Care Resource Center offers a number of programs that promote effective teaching in different ways.
Master Clinical Teaching Fellowships pay selected community physicians a stipend to attend an eight-month series
of seminars on effective teaching practices. The program carries Category I Continuing Medical Education credits. The next
"class" of fellows will start the program in September.
The Teaching Effectiveness Program sponsors workshops to provide formal training in effective teaching
techniques. These workshops, which generally attract UB's regular clinical faculty and residents, focus on specific teaching issues
and carry Category I CME credits.

The Master's Degree in Health Professions Education, designed for clinical instructors, combines Graduate
School of Education courses with independent study.
Community Academic Practice grants support independent medical practices that participate in graduate medical
education. Among the activities eligible for funding by the grants: renovations to provide space for students, or the purchase
ofjoumals or equipment for students. The program also provides each site with computers and access to electronic resources,
such as Medline.
For more information about any of these programs, contact the Primary Care Resource Center at (716) 829-3176.

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�Interdisciplinary Phyllis Leppe rt , R.N ., M.D., Ph.D., is the new department chair
BY

JESSICA

ANCKER

PHYLLIS LEPPERT FIGHTS a many-fronted war on behalf of maternal and child
health. In the course of the battle, she has acquired an impressive array of academic
credentials, published unique research, and worked to build a new ethic of collaboration
among different types of health-care professionals.
Mecca Cranley, Ph.D., dean of UB's
School of Nursing, served on the search
committee that recruited Leppert as the
new chair of UB's Department of Gynecology and Obstetrics. "My agenda was
to get someone committed to interdisciplinary education and practice," Cranley
says. "I didn't realize we were going to
find someone who was herself so interdisciplinary! That was a bonus."
Leppert first trained as a nurse and
then became a doctor. But instead of
abandoning her first profession in favor
of her more prestigious second one, she
has worked to break down cultural barriers between the two.
Leppert loves lab research and earned
a Ph.D. while studying the physiology of
the cervix. While committed to what she
calls "bench research," she has also continued to work on such medical practice
issues as raising health professionals'
awareness of cultural differences.
"It all comes together when you think
that our goal is to reduce the number of
low-birthweight babies and problems in
pregnancy," Leppert says of her varied
career. "We have to work on a number of
fronts--biochemical, obstetrical, socialall at the same time."

An interdisciplinary career
Leppert earned her master's in nursing
from Columbia University and practiced
as a public health nurse in Harlem before
receiving her midwifery certification in
1964. She studied at the Maternity Center Association in New York City, which
offers one of the nation's oldest midwifery training programs.

®

"I had wanted to be a physician since
fifth grade, but it was a time when women
weren't encouraged to do that," Leppert
recalls. "But when I was in my thirties, I
took a look at what I was doing and said,
'Why don't I just go to medical school?"'
She did just that, earning her M.D.
from Duke University School of Medicine in 1973. Leppert completed residencies in pediatrics and in obstetrics and
gynecology and was a Robert Wood
johnson Clinical Scholar at Duke before
accepting a fellowship in maternal-fetal
medicine at Columbia University's College of Physicians and Surgeons. She
taught at Columbia for ten years.
Though Leppert chose to pursue medicine, she has remained involved with midwifery training and practice and continues to value the knowledge and attitudes
she learned as a midwife. For instance, she
says, in normal births midwives
favor a "high-touch" approach
with minimal medical or surgical intervention. Obstetric education focuses on problems in
pregnancy and delivery, an essential field of knowledge, but
one which sometimes can bias
obstetricians to favor a more
high-tech, interventionist approach than is necessary for a
given situation.
"Both approaches are
needed, but we're not always
very good at figuring out which
woman fits in which category,"
Leppert says.
"We need to approach the
question scientifically, deter-

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mine who needs the interventions, and
then make sure they get them."

Firm grounding in research
Leppert believes that all medical care must
be firmly grounded in science-in both
laboratory and epidemiological research.
Her own love affair with research began in
medical school. After a course in immunology, she worked in Duke's Laboratory
of Pediatric Endocrinology under Stuart
Handwerger. "That is something that really influenced my career," she says.
She took advantage of her years at
Columbia to do research on the role of
cervical elastin in gestation and parturition, obtaining a Ph.D. from the Department of Pathology. She has continued to
publish research on the physiology and
endocrinology of the cervix and uterus.
"It's essential that everyone in medi-

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�cine have a strong grounding in science,"
Leppert says. "But in this country we
have tended to put bench research on a
pedestal and pooh-pooh community
medicine. My experience has taught me
that all of it is important. You can't break
these areas apart-you have to be excellent in all areas.
"That's one reason I think UB is such
a good school-it has shown that primary care is important without neglecting research. "
In Rochester, New York, Leppert held
positions in obstetrics-gynecology, nursing, and community and preventive medicine at the University of Rochester, and
was chief of obstetrics and gynecology at
Rochester General Hospital. She has also
served as a consultant to the federal
Women's Health Initiative and recently
completed a Robert Woodjohnson Foundation study aimed at reducing sociocultural barriers to health care.
She co-edited a textbook, Primary
Care for Women, published this year by
Lippincott-Raven Publishers. ("I just had
time to call them and change my title on
the frontispiece from professor at Rochester to chair of the department at Buffalo! " she says.) The text is designed to
provide information for any primary
care practitioners who take care of
women, including nurse-practitioners,
physician-assistants, and physicians in
different specialties.
The book covers a variety of women's
health issues, such as reproductive

health, pregnancy and delivery , and
menopause. It also provides an introduction to a wide range of primary care
issues, such as cardiovascular disease,
derma to logic disorders , and psychiatric
problems, and describes how these conditions manifest in women and what
impact they may have on pregnancy.
Other chapters cover social issues, such
as "cultural competency," the working
knowledge of other cultures needed to
care for a broad spectrum of patients.

ing that way while they're in training, it
might be easier to start working that
way in practice. "
There are other changes she would
like to make. "We have to rethink residency education so it's not so rigid, and
incorporate principles of adult learning.
We have to do more animal labs and
computer simulations and telecommunication. That way, by the time they get
to the patient the residents are more
polished and prepared."

New ideas for medical education

Collaborative practice

While at Rochester General, Leppert
brought together medical and midwifery
education by putting student midwives
in the same learning situations as medical students and residents. She also helped
integrate midwives into the hospital's
obstetrics practice.
She has similar plans for Buffalo. She
is bringing Children's Hospital's four
nurse-midwives into University Gynecologists and Obstetricians, the UB practice plan incorporated last year. With
Dean Cranley's support, she is also hoping to integrate the education of nursing
students and medical students, and to
award some of the midwives faculty appointments in the School of Nursing.
LuAnne Brown, R.N., believes both
doctors and nurses will benefit from
Leppert's program.
"Her idea is very good," says Brown,
the nursing coordinator for maternalneonatal services at Children's Hospital. "It fosters the idea of teamwork. If
you get doctors and nurses to start think-

Leppert once worked in a neurology rehabilitation unit that provided what she calls
an ideal example of collaborative practice.
Each patient was cared for by a team of
doctors, nurses, nutritionists, occupational
therapists, and physical therapists. "The
neurologist was about to discharge one
patient when the occupational therapist
pointed out that the man was still having
trouble doing the kinds of everyday activities he would need to live independently.
And the physician listened. "
Building on this model, Leppert has
been involved in collaborative obstetrical practices in which different professionals cooperate to supervise cases, and
follow the leadership of whoever is most
qualified for each case. High-risk situations may be supervised by a physician;
lower-risk ones by a nurse-midwife.
"It's sometimes hard for physicians to
work this way. We've been taught that
we're the king of the hill," she says. "That's
an attitude I would like to see changed.
We have to respect each other. "+

...THE CHILDBEARING EXPERIENCE Is an intense, memorable event that lasts at least nine months. The health·
care team must provide a nourishing relationship during this time, and because of complex knowledge and the
different skills of various professions, a health-care team works best....
1 believe that no one person should be the "captain" of the team. Leadership is dynamic and fluid and is based on
expertise. For instance, in the case of a pregnant woman with Class C diabetes, the matemallfetal medicine specialist
is the team leader; in a case of straightforward moderate preeclampsia, the leader might be a family practitioner; In
the term twin delivery, the team would be led by an obstetrician; while in a normal birth the team leader could be the
nurse-midwife. In the area of discharge planning, the social worker and family are the leaders.
Different geographic regions of the U.S.A. could and should develop unique matemlty care
Excerpt from "Developteams, just as women and their families should have the right to a team of their choice....
ing sound team relation1believe that the future of matemity care is in a team approach. It will succeed to the extent
ships among maternity
that we emphasize the positive aspects of the health-care team. Developing sound relation·
care professionals," in
Prelude to Action II:
ships calls for mutual respect, openness, and an absolute refusal to carve out territory. The
Reforming Maternity
most important feature in the development of sound team relationships on the matemity care
Care, 1995, a publication
team is a focus on the patient. We always need to ask, "What is best for this particular woman
the Maternity Center
of
and her family?" Only then are team relationships sound and the team approach a success.
Association.

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�OB-GYN yesterday

RANDALL AND WINKLER REUNITED
A DIVIDED DEPARTMENT AT

BY

R ON A L D

E .

BA TT ,

UB
M . D .

' 58

N THE YEARS BEFORE WORLD WAR II, the University of Buffalo's Department of
Gynecology and Obstetrics had become divided into an obstetrics department chaired by
Francis Goldsborough and a gynecology department headed by James King. This academic
division reflected tensions both within the department and within the medical community.
But when the two rival chairmen stepped
down in 1942, they left
heirs who ushered in a
new era of cooperation.
Clyde L Randall and
Edward G. Winkler
served as ideal cochairmen of the Department of Gynecology and
Obstetrics for eighteen
years. They respected
each other, and their interests were complementary, benefiting both
the department and the
practice of obstetrics and
gynecology in Buffalo
and Western New York.
Winkler brings
new surgical techniques
Edward Godfrey Winkler (1901-1960)
went to Georgetown Medical School
and did residency training in obstetrics,
gynecology, urology, breast surgery, and
gynecologic oncology. After returning
to his hometown, he honed his skills as
a chief resident in obstetrics, gynecology, and urology for two years at the
Buffalo City Hospital, under Goldsborough. The two became very close,
almost like father and son.
Winkler entered practice in 1932
at the depth of the Depression. He

®

went to Chicago to
learn the Heany
technique of vaginal
hysterectomy directly from H. P .
Heany. He and
Robert O'Connor
worked night and
day to build the
obstetric-gynecologic
service at Buffalo
City Hospital.
Winkler introduced
low forceps and episiotomy for routine
deliveries, and extraperitoneal cesarean
section to replace classic cesarean section.
Later, he introduced a
low-flap- transverse
procedure to replace extra peritoneal section, and finally low-segment-vertical
cesarean section to reduce the chance of
injury to the uterine vessels. Winkler
was the first in Buffalo to do total abdominal hysterectomy and introduced
the Heany technique of vaginal hysterectomy and repair.
In contrast to the teachings of one of
their influential predecessors (Irving W.
Potter), Winkler and O'Connor taught
that no internal podalic version and
extraction should be performed until
the cervix was fully dilated.

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Recognizing the value of breast milk
to the survival of premature infants,
they introduced frozen breast milk. The
breast milk was put into little cake tins,
set on dry ice to freeze, and then stored
in the refrigerator for use. They reduced premature infant loss from 60 to
10 percent.
Randall focuses on research
Clyde Lamb Randall (1905-1990)
graduated from the University of Kansas Medical School and did residency
training in gynecology, general surgery,
and pathology. While working together
in Buffalo, King and Randall formed a
close relationship.

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�THE N

"I think that the most important thing
I learned from King was to try to be
decent to people," Randall said. "He was
exceedingly kind to his patients. He
liked his patients and he treated them
accordingly." However, King's insistence
on strict routine irritated Randall.
In 194 2, Winkler and Randall declined
offers of full-time positions at Buffalo City
Hospital and Buffalo General Hospital,
respectively. Winkler succeeded
Goldsborough as UB professor of obstetrics and gynecology, and Randall succeeded King as professor of gynecology.
As co-chairs of the department, they
alternated responsibilities on an annual
basis. They developed similar but separate three-year residency programs
which rotated through the gynecology,
gastrointestinal surgery, and breast services at Roswell Park Memorial Institute. Both Randall and Winkler were
excellent surgeons, with remarkable
respect for tissues.
City-wide cooperation
During World War II , many physicians were called into the armed forces ,
and Winkler and Randall experienced
huge growth in their clinical practices. They frequently met, often in
the middle of the night, while attend-

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ing patients in labor. They also met
socially in each other's homes to discuss academic matters and curriculum, but never once did they go to
each other's hospitals. Out of these
meetings they began to hold monthly
combined meetings of their residents
and attending surgeons at the Park
Lane Restaurant on Gates Circle. Soon
they added Herbert Burwig's service
from the Deaconess Hospital and Louis
Mclean's from the Millard Fillmore
Hospital.
Such collegiality greatly ameliorated
the extremes that had marked recent
obstetric practice (e.g., the conservative
management of natural delivery promoted by Goldsborough, and the routine internal podalic version and extraction practiced by Potter) . The city-wide
meetings led directly to the formation of
the Buffalo Gynecologic and Obstetric
Society in 1946.
Different teaching styles
Winkler gave medical students and interns a firm grounding in obstetrics and
gynecology to prepare them for general
practice. Robert Patterson observed: "Dr.
Winkler was very demanding of the
medical students. We had to sit with the
patient during labor with our hand on
the abdomen, and we really learned
about labor. "
Winkler trained his residents as general obstetrician-gynecologists, able to
treat all problems encountered , including breast cancer. The large clinics that he and O'Connor had built up
at Buffalo City Hospital during the
Depression were invaluable for this
education.
The program was highly structured;
residents learned one surgical technique to treat each condition encountered . After mastering the techniques ,
the residents were encouraged to
broaden their experience. Winkler was
directly responsible for training
___Q]:)stetrician-gynecologists and then

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placing the work in their hands by
drawing up regulations to limit the
privileges of general practitioners doing obstetrics.
Randall's residency program was
loosely structured. He allegedly never
performed an operation the same way
twice and encouraged individualized
training of his residents so that they
could develop and expand their special
interests and talents.
Complementary interests
During the tenure of these men as
co-chairmen of the department, the quality of medical education in obstetrics
and gynecology for medical students,
interns, and residents reached an extremely high level. For example, in the
late 1950s, outside examiners of the
residency program thought that the
medical students were residents.
During this period, the University of
Buffalo graduated a higher percentage
of students into obstetrics and gynecology training programs than most other
nonsectarian medical schools in the
country.
Winkler concentrated on medical student education, standardized resident
training, and local medical politics,
whereas Randall focused on individualized resident training, the development
of subspecialists, and leadership in the
National Board of Obstetrics and Gynecology and the American College of
Obstetricians and Gynecologists. Together they combined community and
university resources for optimal patient
care and teaching.
When Winkler died in February 1960,
Randall became UB's first full-time chairman of obstetrics and gynecology. He
later served as the medical school's vice
president for health sciences, acting
dean, and executive officer, before moving to Maryland as director of education
of the johns Hopkins Program in International Education for GynecologyObstetrics. +

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�" BACK IN FAMILIAR SURROUNDINGS, I'M STILL SEElNG THINGS THROUGH A NEPALI TINT ... I CATCH
MYSELF PESTERING MY FRIENDS ABOUT HOW LUCKY
WE ALL ARE, IN AND OUT OF MEDICINE, WITH SUCH
A WEALTHY AND EFFICIENT CIVILIZATION TO GIVE
US MORE THAN JUST SURVIVAL."

Rmedical mission to

BY

DONALD

P.

COPLEY ,

M.D . ' 70

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�T MY TWENTY-FIFTH
medical school reunion last year,
while trading boasts about conquests and crises, I wondered
what, after all, is truly meaningful in this life. I turned to a favorite classmate, Brendan Thomson,
now a pulmonologist in Phoenix, Arizona, and asked, "What
is the most worthwhile thing
you've done since graduation?"
Without hesitation he answered, "NepaL"
Of course I knew that Mount
Everest is in Nepal-I'd even day-dreamed
of someday seeing the world's tallest mountain-but beyond that I drew a blank.
Brendan had traveled to Nepal six times
since 1985 on a variety of medical missions.
The country, which is the size and population of New York State, is strikingly beautiful from jungle to grand peak, mostly agrarian, and painfully poor. With an average
yearly income of only $250 and a literacy
rate of about one-third, Nepal needed lots
of help, Brendan told me.
On his first visit there, Brendan met a
young Nepali physician named Buddha
Basnyat who was intent on an internal medicine fellowship in the United States. Brendan
placed Buddha at a Phoenix hospital and
invited the young man to stay at his home
during the three-year fellowship. The two
have remained close, exchanging visits almost yearly.
Since then, Brendan has acted as a travel
agent for American students and doctors
going to Nepal to study or teach, and he has
helped Nepali doctors come to America to
take board exams. And when Brendan visits
Nepal, he takes other physicians along to
teach and practice.
''I'd love to do something like that," I
said , with visions of trekking in the
Himalayas. "You know what?" said Brendan.
"You can!"
He needed a cardiologist for an advanced
life-support course planned for the next
visit. It wasn't long before I was dashing off
a check for airfare to the other side of the
world.

Getting there
It took thirty grueling hours for my wife,
Andrea , and me to fly from Buffalo to Hong
Kong, where we linked up with Brendan's

small contingent of American doctors and
nurses. After two days of orientation, we
flew on to the burgeoning city of
Kathmandu, 500,000 people nestled into a
story-book valley turned deep green by the
recent rainy season. As our jet banked over
a shrine to land, I caught a glimpse of a giant
figure of Buddha with its life-like tempera
eyes squinting through the smog created by
cheap Indian gasoline.
We headed off in eighty-degree weather
on a kamikaze taxi ride into the city, careening crazily on the British side of the
road. We passed big-wheeled bicycles piled
high with produce, smoky motorcycles
buzzing by like mechanized mosquitoes,
and little blue vans stuffed with people, like
fraternity Volkswagens.
The sweet smell of this sewerless city
was intermittently obscured by clouds of
dense diesel exhaust. At a roadside gutter, a
woman washed her family's clothes near an
array of fresh vegetables piled on the ground
for sale.
We were greeted everywhere with the
Nepali gesture of "hamaste" (pronounced
"hom-a-STAY"), palms together in a prayerful and humble pose, the height of the
hands indicating the level of respect.

A Nepali hospital
About the size of a small community hospital in the U.S., Kathmandu's Patan Hospital
was built a decade ago entirely from church
donations , and it is still run by missionaries. Chief of Medicine Mark Zimmerman
has been there since the day the hospital
opened, when he arrived fresh from his U.S.
residency. His work has been subsidized
every year by a Methodist church in Syracuse, New York.
He relishes what would be intolerable to
most of us: a smothering rush of seriously
ill patients who often arrive too late to be
cured, sometimes even dying on the
hospital's doorstep. He loves the challenge
of functioning with ludicrously limited resources, for next to no pay, with little distinction between work and rest. Smiling
and joking gently, he always looked calm
and content amidst the hubbub.
People, sometimes a thousand in a single
day, walk for miles to queue up at an outpatient window. The sickest patients stay in
one of Patan's 150 ward beds. We toured
the hospital through corridors darkened by

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�power outages. Although the hospital was fairly clean, the
doors and windows were often left open, without screens, to
let the breeze take care of necessary ventilation.
Through a door open to an operating room, a smiling
patient waved to me as his inguinal hernia was being repaired. Latex gloves , considered disposable in the U.S., were
being washed and hung to dry on a large wooden rack,
evidence that the Patan staff wastes nothing.
The hospital survives on donated medical equipment.
Much of it, such as the EKG machines and resuscitation
equipment, came from Brendan and his colleagues. As we
walked by one of Brendan's old cardiac defribrillators, he
whispered, "Think of the lives we've saved by sending this
over!"
The medical wards bustled with patients and their relatives , the latter providing constant nursing care while the
R.N.s attended to technical work. At Patan, the patient's
family must purchase all drugs and supplies themselves from
a nearby pharmacy.
Tuberculosis is the number-one killer in Nepal; pollutioninduced lung disease is the most common non-infectious
problem. Exotic infectious diseases abound: leishmaniasis,
leprosy, rabies.
Many Nepalis smoke-especially the youngsters , who
idolize the American Marlboro image-which gives the cigarette industry a chance to "make a killing. " I saw more
patients with rheumatic heart disease than with heart attacks ,

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but Nepali physicians expect that increased levels of smoking
and urban stress will soon cause a coronary epidemic.
Our students, twenty Nepali resident doctors and thirty
nurses, were hungry for the critical-care knowledge we
taught. We caused some consternation when we challenged
traditional Nepali gender roles by putting male doctors and
female nurses together in the same room and having them
listen to our female nurse lecturers.
We taught basic and advanced life support, the mechanics
of chest compression and the Heimlich maneuver , cardiac
diagnosis and EKG analysis, defibrillation, and drug treatment. Our students asked perceptive questions, the kind that
come from people who have seen a lot. They beamed with
pride when we handed out diplomas on the last day.

Time for touring
e made brief excursions into the countryside to learn
about its beauty-and its poverty. On a 2,500-foot
hike into the foothills of the Himalayas, we puffed
like choo-choos while young children hurried past us
up the paths, carrying cinder blocks in backpacks
supported by forehead straps. Other youngsters
begged us for American ballpoint pens to use at school.
Finally, Mount Everest! A chartered plane took us northwest from Kathmandu , playing hide and seek with lowhanging clouds. Suddenly, there it was , fully visible from its
tropical base at 2,500 feet to its snow-capped peak at 29,000

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�The si&amp;fttof
a man perusing a newspaper 1s not
common, as only about a durd of the
Nepali population can read ThiS set
of donated equipment 111 a fishing
tackle box at Patan Hospital is not
fancy, but it IS adequate to handle
most emergencies. A father gneves
at a child's funeral pyre.

Doctors in Singapore work
mostly in solo practice, without
managed-care headaches, yet
they still feel cost-containment
pressures directly from their patients. For example, angioplasty is
favored over coronary bypass surgery
because it's cheaper, and patients are
willing to return two or three times a year
for repeat procedures. "For my patients, it's
like going to the dentist," said one local cardiologist. I found
Singapore doctors busy and independent, wealthy and content, with a touch of arrogance-similar in many respects to
American doctors of a generation ago.
Back in familiar surroundings, I'm still seeing things
through a Nepali tint, or what's called "perspective." I catch
myself pestering my friends about how lucky we all are, in
and out of medicine, with such a wealthy and efficient
civilization to give us more than just survival. Now I
understand why Brendan keeps going back. He and I are
sure to talk about Nepal at our next reunion dinner as we
contrive another excuse to return. +
'

feet. Microscopic villages
were scattered at its toes like
the patterns of a fine Tibetan
rug. My cherished unlikely
dream had become a reality,
thanks to Brendan's perseverance.
On the way home, we stopped in
Singapore, an Oz-like city with gleaming skyscrapers and
spotless, antiseptic streets. We had received an invitation
from the U.S. Ambassador to Singapore, Timothy Chorba,
whose younger brother, Terence, is a 1979 alumnus of UB's
School of Medicine and Biomedical Sciences.
In Singapore, per-capita income exceeds $16,000, and
there is no unemployment. We lectured at Mount Elizabeth
Hospital, which is about the same age as Patan Hospital but
ages apart in appearance and technology.
About the size of the Buffalo General Hospital, Mount
Elizabeth sparkles from yearly renovations and is blinking
with the latest medical machines and computers. Most patients pay out-of-pocket for their medical services, while
those few with limited resources get a lesser level of care at a
subsidized government facility.

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Donald P. Copley, M.D., practices cardiology and cardiac rehabilitation in
Kenmore, New York. Brendan Thomson, M.D., practices pulmonary care in
Phoenix, Arizona. Both are members of UB's Class of 1970.
For more information about participating in a Nepal exchange, contact
Thomson at 5251 West Campbell, Phoenix, Arizona 85031, (602) 247-7725.

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Tumor viruses and stressed-out bacterta
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or the UB School of Medicine and for a pair of
promising researchers at the National Institutes
of Health, 1995 was a pivotal year.
It was the year that the Lucille P. Markey
Charitable Trust awarded $1 million to expand
UB's young but already internationally recognized Center for Microbial Pathogenesis. And it was
the year that Victor James Hernandez, Ph.D ., and
Maria Laura Avantaggiati, M.D., crossed the Atlantic
to take their wedding vows in Rome.
This year, UB is using part of the Markey grant to
bring the couple to Buffalo. "This is, from our point of
view, a perfect package," says Microbiology chair Ian
Hay, Ph.D. "They both bring to the group expertise
that we need, and they're both superb. We consider
ourselves very fortunate to have them here."
The Center for Microbial Pathogenesis is an interdisciplinary unit with some two dozen investigators
who come from both clinical and basic science backgrounds. Formed several years ago out of collaborative efforts that began in the early 1980s, the center
has garnered widespread attention for its work in
such areas as molecular parasitology, sexually transmitted diseases, and pediatric infectious diseases.
Avantaggiati and Hernandez arrived in early February and promptly set up shop in UB's recently
opened Biomedical Research Building, where
they will continue work
they were pursuing at
the NIH. Avantaggiati
is interested in tumor
viruses and cell growth;
Hernandez is studying
stress response and adaptation in bacteria.
"There is no drug
that will work against
bacteria forever. They
will all become ineffective, " says Hernandez.
"So our hope is to now
find the next generation of antibiotics that
will sustain us for the

next fifty years. It's my premise that these stressresponse systems within bacteria will be very potent
targets for future antibacterial chemotherapeutics."
Hernandez, a native ofEl Paso, Texas, received his
Ph.D. in cell and molecular biology from the University of Texas at Dallas in 1991. For the next five years,
he worked as a postdoctoral fellow in the Laboratory
of Molecular Genetics at the National Institute of
Child Health and Human Development.
Nearby, in the NIH's Laboratory of DNA Replication, Repair, and Mutagenesis, Avantaggiati was studying interactions between viral and cellular proteins.
Born in Naples, Italy, she had come to Bethesda after
three years as a postdoctoral fellow at the University
of Rome, where she had already earned her M.D. "I
wanted to do research, " she recalls. "In Italy, it's very
good, but it's not the center. Certainly the most
important things are going on here."
For about three years, Avantaggiati and Hernandez
would pass in the hall, exchange a polite hello, and go
on to their respective labs.
"It had always been a very formal relationship
until one day I made a conscious choice to go in and
talk to herandget to know her," recounts Hernandez.
"We got to know each other better and began dating.
It was a whirlwind romance." Onjune 1, 1995, they
were married in Italy. "We had a grand party in
Rome," Hernandez says.
That same year, Avantaggiati moved to the National Cancer Institute, where she focused her work
on cellular interactions that appear to have a role in
tumor development. Hernandez pressed ahead with
efforts to disrupt the ability of bacteria to adapt to
stresses.
UB, meanwhile, had already begun using the
Markey grant to recruit new faculty to the Center for
Microbial Pathogenesis. When UB used the grant to
make an offer to the pair, they had already received
other offers. But they selected UB because they were
impressed by both the university and the city. "For
us, things like crime are important, because we want
to start a family," Hernandez says.
Avantagiatti agrees. "The city's very nice. The
people are very kind," she says. "The weather I still
have to adjust to!" +

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• ••••••• ••
~
I

Germaine Buck, R.N., Ph.D.

Epidemiologist appointed to board
of national research agency
,

ermaine Buck, R.N ., Ph.D., associate professor of social and preventive medicine, has been appointed to a three-year term on
the board of the Institute of
Medicine's Medical Follow-up
Agency, an arm of the National Academy of Sciences.
The agency conducts epidemiologic
research on the health status of veterans. Founded shortly after World War
II to conduct follow-up studies of the
wartime experience, the agency now
bases its studies on records from the
military and the Department of Veterans Affairs .
The agency's board is composed of
fourteen physicians and researchers
from universities and research centers
across the country.
Buck has won national recognition
for her epidemiologic research in human reproduction and fetal and earlychildhood health. In 1995 , she was
appointed to a three-year term on the

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National Research
Council Committee on
Toxicology , which
provides expert advice
to government agencies on toxicologic issues and problems.
A prolific researcher, she holds a
three-year fellowship
from the Merck Company Foundation and
the Society for Epidemiology Research to
conduct a long-term
study of the safety and
effectiveness of tubal
ligation.
She holds master's
and doctoral degrees
in epidemiology from UB. She is a
member of the American College of
Epidemiology, the Society for Epidemiologic Research , and the Society
for Pediatric Epidemiologic Research ,
and is a fellow of the American Academy of Cerebral Palsy and Developmental Medicine . +

Wrtght honored for
minortty education
achievements
aggieS. Wright,
Ph.D., assistant
dean for minority affairs , has
received the
Outstanding
Contribution to Medical Education Award
for 1996 from the National Association of
Minority Medical Educators.
Wright was assistant

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dean for student affairs and director of
minority programs for the medical
school before assuming her current position. During her tenure, she has been
director of the Minority High School
Research Apprentice Program, the Science and Technology Enrichment Program for talented minority college students, and the Health Careers Opportunity Program.
A former teacher, Wright earned
master's and doctoral degrees in counseling from UB and worked at the University Counseling Center before taking
her position at the medical school.
Her recent honors include the Sojourner Truth Award from the National
Association of Negro Business and Professional Women's Clubs; the award for
leadership in meeting the challenges of
children with special needs from the
Robert Warner Rehabilitation Center
Division of Human Genetics; the award
from the Buffalo chapter of the National
Medical Association for leadership, commitment, and service; and the award for
outstanding contributions to medical
minority education from the northeast
region of the National Association of
Minority Medical Education. +

�,.

In honor of John Naughton, M.D., the university has installed a bronze bust of the former dean in the Biomedi(al Researth Building. Shown here on the O((asion
of its unveiling; UB President William Greiner, Houghton, S(ulptor Jeff Slomba, University Coundl (hair Philip B. Wels, and Provost Thomas E. Headri(k.

Museum receives $50,000 gift
$50,000 gift from an alumnus
will help support UB's Neuroanatomy Museum.
Willard H. Bernhoft, M.D. '35,
and his wife, Clarice L. Bernhoft,
made the gift in honor of Harold
Brody, M.D., Ph.D., SUNY Distinguished
Teaching Professor in the Department
of Anatomy and Cell Biology, who
helped establish the museum.
"Dr. Brody is a sincere, hardworking gentleman who has been an
inspiration to a lot of medical students
and colleagues at UB," says Bernhoft,
UB emeritus professor of colo rectal surgery. "He devoted much time to this
project and even traveled to Denmark
to learn how to create a neuroanatomy
museum. "
After earning his bachelor's and M.D.

®

from UB, Bernhoft served from 1942 to will join him in supporting UB.
1946 as a neurosurgeon in the U.S. Army,
"New York State doesn't provide the
and traveled to the Philippines and Ja- financial resources needed by the unipan. When he returned to Buffalo, he versity. With the right impetus-that
opened a private practice in colorectal being support from UB alumni and
surgery, from which he retired last year. friends-the university can continue to
The Bernhofts hope their gift will be one of the best in the country." +
attract similar contributions by other medical alumni to help establish an endowed
chair in anatomy in
honor of Brody.
Bernhoft, who has
also been a strong supporter of UB's Willard
Bernhoft and Carlo
DeSantis Library of
Anatomy, Cell Biology,
and
Neuroanatomy, says he
hopes other alumni Clari(e L. Bernhoft and Willard H. Bernhoft, M.D. '35

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Anesthesiology research to be
funded by gift from alumnus

Mefford Diedrick UB'sfirst
medical illustrator, dies

$50,000 gift from Richard]. Nagel,
M.D. '53, has established the first
endowed fund to support research in
UB's Department of Anesthesiology.
"Although the university offers
excellent clinical experiences for its
medical students studying anesthesiology, research in this area is something
that I believe requires more attention,"
says Nagel, UB emeritus professor of
anesthesiology.
"Supporting research now will allow
me to see some results from new UB
studies, and it opens up many opportunities for students to Jearn from these
experiences. I also hope my gift will
encourage others to offer their support
to this fund."
Nagel joined the medical school faculty in 1955 and retired in 1995 . He also
served for four years on the medical
school admissions committee. He was
chair of the Department of Anesthesiology at Mercy Hospital for fifteen years,
and served as chair of anesthesiology at
Our Lady of Victory Hospital in
Lackawanna, New York.
A retired lieutenant colonel of the U.S.
Army Reserves, Nagel is the president of
the South Towns Tennis Center in Orchard Park, New York. +

elford D. Diedrick, UB's first
trained medical illustrator ,
died on January 24, 1997, in
Queenstown, Maryland, where
he had lived since 1982. He was
eighty-four.
Diedrick, who was profiled in the
fall1996 issue of Buffalo Physician, was
the first director ofUB's Department of
Medical Illustration.
A native of Buffalo , he studied art
at the Rochester Athenaeum and Mechanics Institute
(now the Rochester
Institute ofTechnology) in the early
1930s. Later , he
studied at Johns
Hopkins University
under Max Broedel,
who is considered
the father of medical
illustration in the
United States.
Upon returning
to Buffalo, Diedrick
worked in various
capacities at area
hospitals and at the

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medical school until he was hired by
UB as a full-time illustrator.
With his training in both art and
anatomy, Diedrick produced innumerable illustrations for publications and
teaching. He also illustrated medical
stories for newspapers and television.
Among his larger projects~e
three surgical atlases. His last major
project was the 11lustration o
Surgery , by former UB faculty members David H. Nichols, M.D., and Clyde
L. Randall , M.D., a text that is now in
its fourth edition.
Diedrick helped
found the nationa l
Association
of
Medical Illustrators in 1945, and
served as its president in 1963. The
association recently honored
him with a Life time
Achievement
Award.
Diedrick, whose
wife, Bertha, died in
1995, is survived by
his two sons, five
grandchildren, and
one great-grandson .
His remains were
donated for medical
research. +

�•

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Parents'Council aids
medical students
BY

hey drove their children to Little
League, checked their homework,
and kept them in line. Now that
their children have grown, some
parents are still finding ways to
remain active in their children's
lives through the Medical Students Parents' Council, which raises money and
provides unique support services to UB's
medical students.
Robert and Elaine Heichberger, the
parents of third-year student Lisa
Heichberger, are the council's copresidents.
"We both have been teachers all our
lives. When teaching is in your blood,
this type of thing is a natural progression," Elaine Heichberger says. "We are
interested in medical education, have a
great deal of pride in UB, and have an
interest in our daughter's education."
They view the council as a support
post for the students. "The support your
children feel when you are involved
with their medical education, even when
they are married, means a great deal to
them," Elaine Heichberger says. "That
is discussed at the meeting on many
occasions, and the students are very
appreciative."
The council has provided many
things to make students' experiences at
UB more pleasurable. The parents
helped to renovate and furnish the student lounge, supplied the hardware for
the electronic mail system, donated a
fax machine and a copy machine, and
created an annual grant of $5,000 for
the computer laboratory. But their assistance is not limited to tangible items.
According to associate dean Dennis
Nadler, M.D., "the Parents' Council also

VICTOR

FILADORA

provides support for educational missions and activities which benefit the
student body as a whole." For example,
the group sponsors student travel to
national meetings, which Nadler believes has a ripple effect that strengthens the entire class.
Also, during every holiday season,
council members invite UB students
who can't be with their own families
into their homes for support and companionship.
The council, which is unique among
medical schools, was founded ten years
ago by former dean john Naughton,
M.D., as a way for parents to get involved in their children's education.
One of the group's most popular
activities is the annual Gala Dinner
Dance for the graduating seniors on the
evening before graduation. The council

pays for dinner, dancing, a boutonniere
or corsage, and a gift for each graduate.
Parents are recruited during Parents'
Weekend, and they receive a directory
describing the responsibilities and priorities of the council. During the spring
session, the school solicits donations
from the members. Between $15,000
and $20,000 is donated annually; these
funds go directly to student support.
"Reinforcement from the home front
gives students the backing they need so
that they know they are not alone," says
Elaine Heichberger. "The parents realize that it is the little things they can do
which provide extras that students
would otherwise have to do without. "
Although correcting homework and
carpooling to sports practices are no
longer required, the emotional, educational, and financial support of parents
still enriches each medical student's experience and makes medical school at
UB much more enjoyable. +
Victor Filadora is a fourth-year student at
the School of Medicine and Biomedical
Sciences.

ROBERT AND
ELAINE
HEICHBERGER,
THE PARENTS OF
STUDENT LISA
HEICHBERGER,
ARE THE CQPRESIDENTS OF A
UNIQUE PARENTS'
GROUP AT UB.

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get in the way. But that periphery is
made up of human souls, which have a
bunch of that subterranean anger, and
an agenda. And they are the people who
BY
M IKE
M ERRILL ,
CLASS
OF
1 9 97
pay us .
They are trying to get into the examination room, trying to tell us that the
ower, says the I Ching, must be fused with justice. same patients who want us to heal them
"When one understands this," the 3,000-year-old Chi- also don't want their families hobbled
by huge insurance premiums. These
nese book says, "one understands the meaning of people are trying to tell us that we need
to change the way we do things .
everything that happens in heaven and on earth."
We ignore them , or fight them , at
It's quite a point for contemplation: worker bee in times of layoffs.
our peril. They will shape our future ,
Then I went to medical school, or they will , I think, find someone else
power exercised without justice can only
lead to instability, in a government or a plunged into an environment of entitle- to do our work.
business or a family . It leads in the ment and ego and suffering.
The excesses and injustices of the
powerless to a subterranean anger that
I kept working partadministrative and
may build to a destructive explosion.
time at HCP, and I noinsurance systems,
These thoughts bring a new light to ticed a change, a subtle
"LITTLE ACTIONS
just like those of evthe hospitals and clinics. It's easy to distance between me
erything else, eventuAND WORDS CAN
underestimate one's power: watch the and some of my old
ally will be blunted
patients at Erie County Medical Center acquaintances. I have
and
balanced. They
RESONATE DOWN A
deferentially get out of the way of the become one of the obare unstable and so
white coats. Little actions and words jects that the anxiety
will not last, as the I
CHANNEL OF TIME IN
can resonate down a channel of time in fixes upon.
Ching says.
UNFORESEEN WAYS. "
But l think the
unforeseen ways: one elderly patient
I don't like it, but I
physician's role will
refused CTs because a doctor once said can't undo it.
only remain powerful
it would "make slices of the stomach."
As a doctor, it might
to the extent that we
In a way, the I Ching is right. What we be easy to forget the
learn to incorporate,
see going on here in all of human life is fear of losing my job,
in a dignified manner,
the working out of the correct way to the worry about how
the indirect financial
to
pay
for
groceries,
the
exercise power among humans.
concerns
of the paof
unemhorrible
maw
Nowhere have I seen this so clearly as
and
the contients
,
at HealthCarePlan, where I have worked ployment, the anxiety
cerns
of
the
adminisof being without
for six years.
trative environs.
I started there in 1991 as, basically, a health insurance. But
Medicine now has
high-level secretary, continuing as are- these are the fears of
powerful
enemies.
my
co-workers.
When
search assistant for a year, then entering
It's
the
latest incartheir
bosses
get
angry,
medical school in 1993.
nation
of
the
same old
and
their
world
shakes
I was of low rank in the Guaranty
cycle:
power
concentrembles.
When
a
secBuilding in downtown Buffalo that
around
justice,
trates
retary
is
fired,
it
breaks
houses HCP's headquarters. I didn't even
justice
dissipates
, and
the
leg
of
her
family.
need to wear a suit; it would have been
I
know
the
world
of
power leaves. +
silly.
The secretaries and clerks looked the patient will call me.
on me as something of an equal, When I'm in the examination room, Mih e Merrill, afonnerj ournali sl, is a fourth-year
though a bit of an anomaly. I made a wherever I end up, support staff and medical st udent at UB wlwsecolumns appear regulot of friends , heard the gossip , and insurance companies will seem merely larly in the Buffa lo News. He will begin a resishared the helpless anxiety of the peripheral entities that had better not dency in internal medicin e in Buffalo next year.

Medicine is agame of power

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�Aleader in research and in academic administration
FRANKLYN KNOX

or many academics, stepping into administration means
abandoning research. Not for Franklyn Knox.
Internationally known for research on the physiology of the kidney (work that he began thirty-five
years ago while still a graduate student in UB's Department of Physiology), Knox has also helped lead one of the
nation's most highly respected medical institutions through
a period of expansion and change.
He is a recipient ofUB's Distinguished
Medical Alumnus Award, and this February Knox was awarded an honorary
degree from UB during the "Kidney Performs Under Pressure" symposium on
renal physiology.
A native of Rochester, New York,
Knox earned his bachelor's degree in
pharmacy from UB in 1959. In 1965, he
became the first UB student to earn an
M.D. and a Ph.D. concurrently.
"I had entered medical school with
the idea of a career in research and teaching, and it became evident to me that I
needed further training in research, so I
embarked on the Ph.D.," he recalls.
"My decision to pursue renal physiology had more to do with my mentor,
Don Rennie, M.D., than with the kidney
itself. I first met him when he taught the
medical school physiology course, and
then I did research in his laboratory in
the summers.
"One of his many research interests
was kidne y function . But under
Hermann Rahn's leadership, the Department of Physiology largely focused on
respiratory physiology. As a result, we
studied respiration of the kidney."
Knox worked for three years at the

®

,..

'65 , DISTINGUISHED INVESTIGATOR AT THE MAYO FOUNDATION
accomplishment I point to with the greatest degree of pride," Knox says.
Before 1982, the Mayo's medical and
Ph.D. degrees were granted through the
University of Minnesota. Under Knox's
leadership, the Mayo became accredited
to take full responsibility for both degree programs. "In some sense, the
change was a 'truth-in-labeling' issue,
because all the medical curriculum was
being taught here at the Mayo anyway, "
Knox points out. "The decision for us to
independently grant Ph.D . degrees, as
well as M.D.s, has resulted in much
stronger basic science education here."
He has also been involved in other
major changes at the Mayo. The Mayo
established full clinics in jacksonville,
Florida, and Scottsdale, Arizona , in order to make its service and reputation
more national in scope. It has also instituted a series of changes in response to

National Heart Institute's Laboratory of
Kidney and Electrolyte Metabolism,
moving to the Department of Physiology at the University of Missouri School
of Medicine in 1968. Two years later, he
joined the Mayo Clinic and entered its
Department of Physiology and Biophysics, which he later chaired.
He was then appointed Dean of
•=
the Mayo Medical
•
School as well as
director for education of the Mayo
Foundation, with
huuu hu
responsibility for
supervising undergraduate and resident medical education, the Ph.D.
programs, and the
health-related science programs, as
well as continuing
medical education.
"The establishment of the Mayo
as a degree-granting institution in
its own right is the Interim medical school dean John Wright, M.D., with Franklyn Knox

.

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James E. Springate;
joey P. Granger, of
the University ofMississippi; University
of Alabama professor
james A. Schafer, the
president of the
American Physiology Society; and the
society's president-elect, Allen W.
Cowley Jr., of the Medical College of
Wisconsin.
Knox spoke about his recent research
on the kidney's natriuretic response to
increased blood pressure.
Two observations-that patients who
take non-steroidal anti-inflammatory
drugs ( SAIDs) over a long time increase their risk of hypertension, and
that NSAIDs block prostaglandin synthesis-raised the question of how prostaglandin is involved in natriuresis,
Knox said.
He traced the sequence of events
through which, in healthy individuals,
increased blood pressure is reflected in
increased renal interstitial pressure,
which triggers pressure natriuresis to
help lower blood pressure. In hypertension, a number of factors can interfere
with this cascade.
Knox's experiments showed that lanJESSICA
ANCKER
thanum ions crossed the epithelium of
the proximal tubule via the tight junctions between the epithelial cells.
Knox used these findings to argue
that prostaglandin helps maintain the
permeability of the tight junctions, and
D.
that this permeability accounts for a
he kidney's regulation of blood substantial fraction of the transepithelial
pressure relies on the paracellular transport of water and electrolytes. Thus,
transport of water and sodium in he said, prostaglandin synthesis amplithe proximal tubules, Franklyn fies the natriuretic effect of increased
Knox argued in February's D. W. blood pressure.
The D.W. Harrington Lecture series
Harrington Lecture.
brings
distinguished scientific speakers
Knox's lecture was the cornerstone
UB
twice
a year. The series is funded
to
of the "Kidney Performs Under Presendowment
created by Harrington,
by
an
sure" renal physiology symposium at
a member of UB's class of 1871. +
UB's Center for the Arts in February.
-].A.
The other speakers included UB's

managed-care pressures, including developing its primary
care network and affiliating with a network of hospitals and
clinics.
Knox credits the
Mayo's strong administrative support structure with allowing
him to continue being an active researcher
throughout his administrative career.
"Also, there's an expectation that administrative responsibilities will rotate, so
people are encouraged to maintain their
professional research roles throughout different administrative jobs."
He now holds the title of Mayo Foundation Distinguished Investigator and
Head of the Nephrology Research Unit
of the Mayo Clinic and Foundation. He
has served on numerous national and
international editorial and advisory
boards, and is a past president of the
American Physiological Society and of
the Federation of American Societies for
Experimental Biology. His recent research focuses on the regulation of phosphate metabolism and the role of blood
pressure in controlling electrolyte and
water excretion. +

1kw Y• S Hwl COIIIIIIISSIOII 8arltara A.
De8uono, H.D wl be the keylole speaker at DB's
60dl Annual $pMg OilicaJ Day OD April 26, ID a
pni&amp;IUI eatided "1lle blienillg of llealdl Care..
The pregnll at tile Buftalo Marriott IS
designed to Dlfer physicials ilsigllts and answers
to the prolllems ucl epportunltleS of medial
practKe, aCtOnllng to program chair Richard
Collins. H.D '83.

8 a.m. Welcome and Introduction
Jadt f Coyle. H.D '85, presideat. "edial
Alumni Association
~ L Wright. M.D., 111ten11 dean. Schoel of
ltediCIIe ud lioiiHal Scieltes
' lidtanl L Colas. "0 '83, prop~ dlair

Paracellular transport in the
kidney: the W. Hanington Lecture

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Fw more ln(onnotlon about Sprinc ClniaJI
OCiy Gild ocher Alumni Weeltend Cldlwflies,
, . _ coneoct die Medical AUnnl
Alsodar.ton CJt 7111-129-2778

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HURWITZ &amp; RNE, P.C.
[ATTORNEYS

AT

LAW

I

I
1

S ERVICING
T HE L EGAL
N EEDS OF THE
H EALTH S CIENCES
C OMMUNITY
• Managed Care

9

JOHN

D.

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WHITE '40 , of]acksonville,

1

FL,

has moved with his wife, Dorothy, to Cypress Village, a retirement community next
to the Mayo Clinic. He continues to be active
in low-vision counseling and community
affairs. He writes: "I would like to know why
we don't have news of the '40s classes. I can't
believe that they are all dormant. If you get
to Florida, I'd like to see any of you!"

• Purchase &amp; Sale of Practices
THEODORE W . KOSS '41 , of Smithville,

• Business &amp; Tax Planning
• HCFA Safe Harbor Regulations
and Physician Self-Referrals

TN, has had a good recovery from both a
total hip replacement and a coronary occlusion last fall. ''I'm doing exceptionally well,
fishing and following the market."

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MORTON PAUL KLEIN '62 ,

of Boynton

Beach, FL, is retiring from ob/gyn after 28
years. He plans to travel through the United
States and Canada in his new motor home.
HARVEY LIEBESKIND '63 ,

of Jackson-

ville, FL, writes: "Although I continue to
practice psychiatry part-time in Jacksonville, most of my time over the past 20 years
has been devoted to the thoroughbred horseracing and breeding industry as an owner. I
attend all the major thoroughbred auctions
and race principally in New York, Kentucky, and Florida. Two of my three sons are
in the business with me. I'm looking forward to our 35-year reunion in 1998."

• Contracts with Private

&amp; Public Entities
• Employee Relations
Counseling
• Fringe Benefit Programs
• Representation Before
Government Agencies on
Audit &amp; Business Issues
• Facility Finance
and Construction
• Credentialing
and By-Laws
• Hospital/Medical Staff Issues

Please contact
Robert P. Fine or
Lawrence M. Ross
at 716- 849- 8900

HAROLD PESCOVITZ '47 , of Cincinnati,

OH, has retired from his practice of surgical
oncology. "I winter in Boyton Beach, FL,
and summer in Cincinnati, so 1see no snow."
of Buffalo,
NY, received the Senior Honor Award Cer-

ARTHUR J . SCHAEFER '47 ,

tificate for his many years
of service to the American Academy of Ophthalmology and its scientific
and continuing education
programs. The award was
granted at the academy's
100th Anniversary Meeting in Chicago on Oct. 25, 1996. At the
meeting, Schaefer was one of five past presidents of the American Society of Ophthalmic
Plastic and Reconstructive Surgery who gave
a three-hour instruction course, "Refinements in Surgical Techniques in the Treatment of Ptosis, Entropion, and Ectropion of
the Eyelids."

STEPHEN

C .

SCHEIBER

' 64 ,

MARC COEL '68 , of Kailua,

HI, is chair of

nuclear medicine at the University of Hawaii School of Medicine and director of
nuclear medicine at Queens Medical Center. He writes: "I have had a nuclear medicine text (atlas) published by Saunders. 1
would be interested in hearing from members of the class of'68living in Hawaii. I live
in Kailua, across the mountains from Honolulu, where I work ... a bit warmer than
Buffalo this time of year."

s . K. Bosu '69, of Anaheim, CA, has been
C .J . PARKER '58, writes that he has moved

from Detroit, MI, where he was an associate
professor of biochemistry, to Hayes, VA.

1300 Liberty Building
Buffalo, New York

appointed director of the N.I.C.U. and clinical chief of pediatrics at Southern California
Permanente Medical Group in Orange
County. He was also recently elected to a
two-year term as president of the Association
of Nigerian Physicians in the Americas, a
2,000-member professional association.

®

of

Deerfield, lL, was elected chair of the Committee of Board Executives and Representatives of the American Board of Medical Specialties. He was also approved for membership in the Benjamin Rush Society and the
University Club. Scheiber is secretary of the
Group for the Advancement of Psychiatry
and treasurer of the American College of
Psychiatrists.

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I N FIN I T I
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ARTHUR R . GOSH IN

THOMAS ARNO

'70, of Buffalo, NY,

was selected by the Academy for International Health Studies to
travel to jerusalem for a

'78, of Meadville, PA,

was awarded the 1996 D'Angelo Excellence
in Heart Care Award by Hamot Medical
Center. Arno is medical director and chief of
cardiology at Meadville Medical Center. He
was honored for improving cardiac care and

week of study of the Israeli
health-care system. He
joined a delegation of 18
American health-care leaders that met with Israeli

raising public awareness about heart disease. Among his accomplishments were adding new services at the hospital, writing
medical columns for the local newspaper,

Minister of Health joseph
Matza; members of the Brookdale Institute;
the mayor of Jerusalem; and the chair of the
board of Israel's largest HMO, which has 3.4
million members. Goshin is president and
CEO of Buffalo's oldest HMO,
HealthCarePlan. He is also board chair and

appearing on the radio to raise awareness of
heart disease, and helping in the annual
Heart Fund Drive.

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'82, of Los Alamitos, CA,
was recently advanced to fellowhip in the
American College of Physicians and continues to practice pulmonary and critical care
medicine in Orange County, CA. Having

'74 , of Seattle, WA, writes:

been promoted to the rank of commander in
the Navy Reserve Medical Corps, he has
attained qualification in surface warfare
medicine on the U.S.S. Kitty Hawk and was
recently awarded the Navy Commendation
Medal. He and his wife, Pina Wong, M.D.,
have one daughter, Christen Marie, who is
experiencing the 'terrible two's. '

"I have joined the Richmond Clinic and am
starting an internal medicine practice. I will
be living in North Seattle with my wife,
Claudia, my daughter, Nicole, and my granddaughter, Samantha."
RICHARD

AL TESMAN

'76 , of White

Plains, NY, writes: "After 10 years in the
private sector, I've returned to academia as
director of the acute division of New York
Hospital-Cornell Medical Center in
Westchester County. I still maintain my
psychiatric consulting practice."
TAWNI ANN FRANK

'76 ,ofCharlesCity,

VA, writes: "After eight years working as a
general practitioner and ER doc, I found my
true calling in psychiatry. I am now an
assistant professor in the Department of
Child Psychiatry at the Medical College of
Virginia in Richmond."
MIKE NEANDER

'76 , of Oneonta, NY, is

practicing child, adolescent, and adult psychiatry in rural upstate New York, and works
monthly in Washington, DC. He works with
families with multiply behaviorally challenged children.

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An interior more Jpaciou,l than a Ro//.1 Royce
Silo•er Spur Ill. An e.-cceptionaffy generow liA
of ,1tandard Lu.-wry featured. A 190-hp V6
capahle of out-acceleraltizg many Lnxury V8J.
And of courJe, !he Jtandard-Jetting
performance and Jervice oflnfiniti.
$599 mo. 36 mo. LeaJe $999.00 down

MARK CHUNG

CEO of Vytra Healthcare, a HealthCarePlan
subsidiary on Long Island.
JOHN J . FIN A

The fro nt-wheel drive I nfiniti® /50™

'82, of Grand Island,
NY, is director of laboratories and chief of
pathology at the Niagara Falls Memorial
Medical Center. He has been granted voluntary recertification by the American Board
of Pathology. Gioia is board-certified in anatomic and clinical pathology and is a clinical
assistant professor at UB.

JOSEPH F . GIOIA

'83, of Memphis, TN,
writes: "After a decade in academic medicine, including the last two years as chief of
the division of geriatrics at the University of
Tennessee at Memphis, I will begin a new
adventure this year. I am joining St.j oseph's
Hospital in Memphis to become the medical
director of a MedWise Center. MedWise is
run by GeriMed of America, a national company providing primary care for older adults
throughout the continuum of care. "
ROBERT BURNS

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I ntrouucing the all neov 9 7' QX4®
from Sj5,550.00
In an ln/inili® QX4®, one of the firJt
lhingJ you 'If eJcape iJ the mundane.
Beca11Je the QX4 iJ not your typical
La.xury .1porl utility l'e!Jicle. While it offet~'
all the verJatility you e.-..:pect from a
l'ehicle of it,, kino, I he QX4 offeN
.wmething you don't e.-..:pect: the Lu.-..:ury
of an infiniti.

I N F I N IT I

AUTO PLACE INFINITI
8129 MAIN ST. , WILLIAMSVILLE

633-9585
East of Transit Rd.,
Near Eastern Hills Mall
( 130-$450). Bank fee + tax and license
due at inception. 12,000 annual mileage .
$.15 per mile in excess.

�&amp;

WILLIAM J . MAYER '83 , of Portage, MI,
was recently appointed president and gen-

THE ULTIMATE DRIVING MACHINE=

eral manager of the Functional Foods Divi-

Advertise in one of the
finest publications in
Western New York ...

Buffalo Physician

~ Uf\"tj

v"~ s \ [ \ ""

Checkpoint
Foreign Car, Inc.

sion of Kellogg Company. He also served on
an Institute of Medicine study committee
that published Improving Health in the Community. He and his wife, Annie Fainsinger,
have two sons, joshua (5) and Adam (2).
EDWARD A . ZANE '84 , of

ew Milford,

CT, writes: "After serving as chairman of the
Department of Anesthesiology, I have been
elected to serve as president of the medical
staff of

ew Milford Hospital. Our three

children-Alexandra (8), Erica (6) , and
Mauhew (4)-bring endless joy to Debbie
and me."
OONNICA L. MOORE '86 , of

Sales and Service

eshanic

Station, NJ, has been elected vice president
for membership of the

•

American

Medical

Women 's Association.

487 Kenmore Avenue
Buffalo, NY 14223

Moore, a gynecologist, has

Give us a call:

836-2033

(716) 645-6933

•

Michael J. Baranski
Marketing Representative

also been named president
of Sapphire Women 's
Health Group, which provides consulting services
to companies and organizations interested
in enhancing their position in women's

Your WNY Leasing Specialist
Serving WNY proudly
for 33 years

health. She will also serve as the program
chair for the Fifth Annual Congress on
Women's Health in Washington, DC, in
june. She writes, "I hope to see many alumni
there! "
JOHN BARBACCIA '88 and JANET WILLIAMS '88, ofMorgantown, WV, announce
the birth of their son,

icholas Andrew, on

Dec. 31, 1996. He joins three older siblings:
Katie (5), Matthew (3), and Thomas (1).

1

BARANSKI
ADVERTISING

146 Stepping Stone Lane
Orchard Park, NY 14127

®

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PAMELA A . CLARKE '90, of Prospect,
KY, writes: "I finished my pediatric endocrinology fellowship in june 1996 and accepted a position as assistant professor at
the University of Louisville in the Division

hysician

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II
'

of Pediatric Endocrinology. My husband,

begin a two-year fellowship in pediatric oto-

Mike, and I have been keeping busy build-

laryngology at Emory University in Atlanta

ing our dream home."

this July.

GLEN M . GINSBURG '90 ,

of Omaha,

JONATHAN WEINSTEIN

I

'93, of Alexan-

NE, was appointed assistant professor of

dria, VA, writes: "I have finished my resi-

pediatric orthopedic surgery and clinical

dency in pediatrics at Children's

director of the Motion Analysis Laboratory

Medical Center in Washington, DC, and

ational

at the University of Nebraska Medical Cen-

have joined a large practice in Fairfax

ter after completing a fellowship in pediatric

County, VA. I love living in this area and

orthopedics at the University of Southern
California.

take advantage of the many sights and activities. I just finished my second Marine
Corps Marathon-with my father! Ed Math

LINDA D . LORENZANI - FRANCIS '91 ,

of Washington, NC, writes: "I finished my

and I keep in touch frequently and occasionally I hear from Andy Corsello. "

psychiatry residency at Sheppart Prall Hospital in Baltimore in 1995, and I've joined
RESIDENTS

the faculty at East Carolina University School
of Medicine's Department of Psychiatric
Medicine in Greenville, NC. "

W I LLIAM A . PULLEN ( 1982- 85) ,

of

Los Angeles, CA, was chosen as one of the
best physicians in Los Angeles by Los-Ange-

MATTHEW J . PHILLIPS '91 ,

of Snyder,

NY, writes: "My wife, Toula, and I are proud

les Magazine. Pullen is married to JoAnn C.
Pullen '83.

to announce the birth of our son, Mauhew

John Phillips Jr., on Nov. 9, 1996. He joins
his brothers James (3) and Michael (2). "
of
Amherst, NY, is completing the last year of
her otolaryngology residency at UB and will
PHILOMENA MUFALLI BEHAR '92 ,

MANDEEP KAUR RAI ( 1992-95),

of

Chagrin Falls, OH, was awarded an educational grant from the National Foundation
for Infectious Diseases to attend the 1996
lnterscience Conference on Antimicrobial
Agents and Chemotherapy last fall in ew

Orleans. Rai is a fellow in infectious diseases
at Prompt Care and the Cleveland Clinic
Foundation.

NICHOLS
MIDDLE SCHOOL
• Challenging, mnovative curriculum
• Outstanding preparation for high school
• Average class size of 14 students
• Interscholastic sports
• Comprehensive visual and performing
arts program
• Dedicated, caring faculty
• Financial aid available
For further information, call:
NICHOLS MI DDLE SCHOOL, 175 Nottingham Terr.

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NICHOLS UPPER SCHOOL, 1250 Amherst St.

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875~8212

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·············· · ···· · ········· · ····· · ··········· · · · ···· · ············ · ·· · ········ · ······ · ···

I

OBITUARIES
STEVEN PIERI '36,

of Fort Myers, FL,

died on Dec. 18, 1996, after a long illness.
After graduating from UB, he received further training from the People's Hospital in
Akron, OH, and the Belmont Hospital in
Chicago. In 1939, he started a group practice in Corning, Y, and worked there until
his retirement in 1981. He was also a member of the staff at the Corning Hospital and
was active in the Steuben County Medical
Society. He is survived by his wife and classmate from UB, Doris Pieri '36.
JOHN

L. MUSSER '51 , of Orlando, FL,

diedjan. 19. He had been battling cancer. He
is survived by his wife, Norma.
JEFFREY J . SEYMOUR '93 ,

of Ilion,

NY, died jan. 6 as a result of injuries sus-

tained in a car accident. He was 31.
Seymour was completing his residency in emergency medicine at
Albany Medical
Center, where he
had become chief
resident. He earned
his bachelor's degree from Cornell
University after attending Herkimer
County Community College. He graduated
from UB School of Medicine and Biomedical Sciences with honors. In 1995, he married Pina Sanelli, UB Class of '94, who is
now a resident in radiology at Albany Medi-

This photo of Jeffrey Seymour and Pina Sanelli
appeared in the 1993 Iris, UB' s medical
student yearbook.

cal Center.

If you come loolring for a car,
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(716) 831-3100 • (716) 835 FAXX (3299)

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�Put tfte best seat in tfte fwuse
myourgarage.

UBMICRO
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�Who says there's nothing good on TV? As busy as
they are, physicians and other health care providers
always take the time

to watch MLMIC's top-rated

risk management education programs. • When they
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BUFFALO PHYSICIAN
STATE UNIVERSITY OF NEW YORK AT BUFFALO
3435 MAIN STREET
BUFFALO NEW YORK 14214

ADDRESS CORRECTION REQUESTED

PLAN'l'ING

A TREE

UNDER WHICH

You WILL NEVER Srr

DR. DEVILLO W. HARRINGTON, class of 1871, knew how to make his money grow. In fact, this man who in 1905 provided $5,000 through his
will for the University at Buffalo School of Medicine, is still supporting UB today through the endowment his bequest created.
THIS PERMANENT endowment in Dr. Harrington's name has grown to over $300,000 and today it supports the famous
Harrington lecture Series, which twice a year brings distinguished scientific speakers to the School of Medicine and Biomedical Sciences.
DR. HARRINGTON'S LEGACY to UB is just one of many bequests which have established permanent and important endowed funds at
the school. They enable UB to provide scholarships ·to outstanding students, enhance scientific research, support excellence in teaching and
meet the ever-changing needs of the school.
YOU TOO can provide the School of Medicine with a measure of permanence through a bequest. Proper estate planning helps you
develop a smart financial plan. Acharitable bequest provides the satisfaction that comes from planting a tree under which you will never
sit, but which will bear fruit for generations to come.
FOR ACONfiDENTIAL consultation on making a bequest to the UB School of Medicine and Biomedical Sciences, or to receive
materials to share with your attorney or estate planning advisor, please contact
STEPHEN A. EBSARY, JR.

I

Assistant Dean and Director of Development, School of Medicine and Biomedical Sciences

UNIVERSITY AT BUFFALO

(716) 829-2773

UNIVI!ASITY AT BUFP'ALO
SCHOOL OF MI£DICINII!:

l50
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18415-1998

�</text>
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                    <text>�Dear Alumni and Friends,
BUFFALO PHYSICIAN

\ olumr 31 '\umhcr 3
ASSOCIATE VICE
PRESIDENT FOR
UNIVERSITY SERVICES

Dr ( ;.uolt "'mlth Pt•tro
DIRECTOR OF
PUBLICATIONS
h.athn n \."a\\ ncr
EDITOR

Jr ...... ila \n&lt;.:krr
ART DIRECTOR

\l,m J 1-;egkr
PRODUCTION MANAGER
\nn Ras::mann Bn)\\ n
STATE UNIVERSITY OF
NEW YORK AT BUFFALO
SCHOOL OF MEDICINE
AND BIOMEDICAL
SCIENCES
Dr John R. \\ nght lntt:l rru Dnm wul

1·;" Prnulnli{&lt;H Clu1iwl

\ffw"

EDITORIAL BOARD
Dr Bcnram Portm Cha1r

Dr
Dr
Dr
Dr
Dr
Dr
Dr
Dr
Dr
Dr
Dr

\larun Brecher
Harold Brod1
R1chard L Coll11"

Lmda J. Corder

.I ian J Dnnnan
James Kansk1
Barhara \laJrrom
Llizahrth Ohmtrd
Ch.trlrs Paganelli
Stephen Spauldmg
BradiC\ T Trua"'
Roy \ 'ongtama
Dr I ranklm Zcplo11 liz

THIS I''L r or Bt FHW P11n1c 1.\\ marks a significant change for
the school. After nearly two years as editor of Buffalo Phvsician,
jessica Ancker has accepted a new opportunity elsewhere. \\"e all
wish her well and thank her for her many outstanding contributions to this publication. During our search for her successor.
judson Mead, editorial manager of the lJB Publications Office.
will sene as interim editor.
On May 11 , 1997, we celebrated the medical school's l5lst
commencement, graduating l-+6 men and women as doctors of
medicine and 37 as doctors of philosophy; four received bo th
degrees simultaneously. At the ceremon), an honorary doctor of science degree was
awarded to Dr. james Holland. a distinguished former member of the Roswell Park
Cancer Institute and of the university.
Our incoming medical student class is now complete, and we look forward to
greeting this group a few short months hence. \\"e are also welcoming new house
officers. many of them our own recent graduates. The new chief residents also begin
their final year of residency and, along with the ne\\ residents. will participate in
comprehensive orientation programs orgamzed by the Graduate Medical Dental
Education Consortium, a legacy of former dean john Naughton ably directed b)
associate dean Dr. Roseanne Berger. The introductory programs pro\·ide incoming
residents with the latest medical, legal, and administrative updates and teaching!
evaluation skills, as well as basic and advanced life-support training. Much credit is
due to Dr. Berger for her commitment and dedication to this effort.
As we continue to struggle through the fiscal maze so commonplace in today's
medical schools and universities, we arc deeply grateful to you, the alumni and friends
of this uniwrsity·. for your generous sharing of time, energy, and yes, worldly goods,
to this noble cause. Please accept this sincere thank-you for your help.

/f

John R. Wright, M.D.
/ntaim Dean, School of .\lcdic111c and Biomedical Sncncrs
lntnim Vice President for Clinical A/fails

TEACHING HOSPITALS AND
LI A ISONS

The Buffalo (,rnrral llospllal
\fulwd ~~~"''
The Children's llospnal of Buffalo
Ene Counl\ \lrdtcal Center
\lerCI llralth ''stem
\Iiiiard 1 Hlmore llealth ~ystrm
l·ranlz S£1HI
'\iagara l·alls \lrmonal \lcd!cal
Center
Ro~wcll Park ( &lt;.lnccr ln-,ttlutc
Sisters of Charll\ llospllal
Dntnis \frCatth\
\'eteran!-, .\.ff..l irs \\·estern ~ew York
Hcahhcare '-,ystcm
([)The ~tate UniH·rslly of :'\e\\ York
at Buffalo

Buffalo PI"'""'" IS published
quanerh h) the State Lmversilv of
~e" \ork at Buffalo School of
\1cdicinc and Biomedical Sucnccs
and the Off&lt;ce of Puhhcat10ns. It "
sent, free of charge, 10alumni. facultY .
students. residents. and friends. The
staff reserves the nghtto cdll all cop)
and submtssiono.; accepted for
publication .
.:\ddress questions, comments. and
subnu,;10ns to The E:dllor, Bt&lt;{falo
Phrskian, State Lmvcrsny of !'Jew
York at Buffalo, Office of Puhhcat!Ons. 136 Crofts Hall. Buffalo.

'\\ 1-+260

Send address changes Ia:

Buffalo
Plll\«i&lt;lll 1-+6 CFS .\dduwn H35
Mam Street Buffalo,"' 1-+21-t

Greetings!
A., THL ~EI\ t 1 LUCTED PRE,IDE"'f of the Medical Alumni Association,
I am honored, proud, and humbled when I consider the quality of the
individuals this organization represents. The 60th annual alumni
weekend and Spring Clinical Day was a resounding success, thanks
in no small part to Richard L. Collins, M.D., who put together an
outstanding program.
New York State commissioner of health Barbara DeBuono, M.D.,
M.P.H., updated attendees on the political and legislative aspects of
managed care in New York State. john Friedlander, president and
CEO of CGF Health System, presented the case for mergers. Steven R.
Peskin, M.D. , talked about the evolution of managed care across the country. Irene S.
Snow, M.D., spoke about practicing medicine under managed care. As a recent past
president of the Eric County Medical Society, she has a unique perspective. She emphasized her personal involvement with patients, associates, and local, state, and national
medical and specialty societies.
Highlighting the program was the induction of two honorary medical alumni-john
'\Iaughton, M.D., our recently retired dean of 22 years, and john Richert, Ed. D., our
recently retired associate dean for medical alumni affairs. Each of them played a major role
in making the school and the alumni association what they are today.
There are some special people who deserve recognition for their support of this
association: Nancy Druar, our administrative assistant; Bertram Portin, M.D. , our new
associate dean of medical alumni affairs; and jack F. Coyne, M.D., our past president. We
also wish to thank our interim dean, john R. Wright, M.D., for his support and
participation. With the continuing support of these individuals, I am looking forward to
a successful and enjoyable year.
Sincerely,

~,d::Mf'~
Pres1dcnt, \lediwl Alumni Assocwtion

�-

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VOLUME

-

-

31,

NUMBER

3

S UMMER 1 i i i j

Sp~ing

2

Clinical Day

THREE PRESENTATIONS LOOK

AT DIFFERENT ASPECTS OF

CHANGE IN HEALTH CARE.

8

UB's New Specialty
Dental Clinics
DENTAL MEDICINE AND

MEDICINE OFTEN CONVERGE

IN St;IUIRE HALL .

10

D~. Cong~essman
DAVE WELDON ' 8 1

IN

THE HOUSE I S

SAYS LIFE

LIKE BEING

AN INTERN YEAR-ROUND.

by Clare O'Shea

by Rosemary E. Frei

Medical School News
MATCH DAY . TWO FORMER

FACULTY REMEMBERED. NEW

CHA I R OF PEDIATRICS.

t-1AMES PLATT WHITE HONOR

ROLL.

Commencement '97

PIONEERIN G THE

Alumni News

CLINICAL CURRICULUM.
THE PICTURES SAY IT ALL!

NEW ALUMNI ASSOCIATION

RESIDENCY SLOTS.
OFFICERS. HONORS FO R

AStudent's Perspective
LE ARNING ABOUT ASTHMA

FO UR. 60TH ALUMN I

WEEKEND.

AT STREET LEVEL.

by Michael Kane, Class of 1998

Classnotes

THE QUOTE ON THE &lt;OVER is hom ·APhysicion'sOoth; odoptedfromonewrittenby louislnsogno,

M.D., deon of the Sockler School of Groduote Biomedical Sciences ond deon for ocodemic offoirs of the
Tufts University School of Medicine.
As port of commencement exerc~es eoch yeor, groduotes of the UB School of Medicine ond
Biomedical Sciences rise ond formally sweor to fulfill, to the best of their ability ond judgment, this covenant.
In oddiHon, three yeors ogo onew tradition wos born ot the UB medicoIschool: On the first doy of orientoHon
eoch yeor, the ooth is reod ond discussed with students os omeons of impressing upon them the full significance
of the program they ore obout to undertake.
The complete text of the ooth is featured in the Autumn 1996 issue of Buffalo Physician.

s

5

J':J~l

~

�SPRING

SI

X

T

ANNUAL

I ETH

ALUMNI

WEEKEND

CLINICAL

DAY'97

Health commissioner
discusses state P9licy in

B y

JESSICA

Stockton Kimball Lecture

ANCKER

are creating tensions between private conscience and
public policy, and nowhere are those tensions more obvious than in the office of New York
State commissioner of health Barbara A. DeBuono, M.D., M.PH.
CHANGES IN AMERICA

HEALTH CARE

DeBuono, who delivered the annual Stockton Kimball
Lecture as part of the 60th Spring Clinical Day on April26 at
the Buffalo Marriott hotel , plays a pivotal role in the development of the state's health policy. That often puts her in a
tough position, as she illustrated
by describing a case that recently
reached her desk in Albany, Y.
A patient received a diagnosis
that indicated a Whipple procedure (pancreaticoduodenectomy),
DeBuono said. His insurer, a managed care organization, supplied
the names of three surgeons in his
city qualified to do the procedure.
But the patient, seeking what
he felt would be the best possible treatment , underwent
surgery at Memorial SloanKettering Cancer Center. His
HMO refused to pay the bill or
even to cover what the approved
doctors would have charged.
The patient appealed to the state
health commissioner.
On the one hand , DeBuono points out, the patient broke
the agreement he made when he enrolled in his HMO. That
agreement allowed the insurer to control its costs (and his
premiums) by controlling where he could seek medical care.
On the other, the patient wanted the best possible care.
"And why shouldn't he get the best? " DeBuono asked.
But there's no concrete evidence that the procedure performed at Sloan-Kettering was of substantially better quality
than what the local surgeon would have done. While it is
PHOTOGRAPHY

0

universally accepted that surgeons who perform high volumes
of cardiac surgery have better outcomes, there is no comparable body of research on Whipples.
When it comes, DeBuono's decision may have broad
economic and political ramifications. If she decides in the
patient's favor , will millions of
ew Yorkers get the message
that they can go out of plan
whenever they want? But if she
decides in favor of the insurer,
could that lead to further restrictions on care? And how will
the patient at the core of the
case pay his bill?
This case was one of the
manypublidprivate health-care
issues DeBuono discussed at
Spring Clinical Day.
DeBuono received her M.D.
at the University of Rochester
and completed her residency at
the ew England Deaconess
Hospital in Boston. She then
earned a master's degree in public health from Harvard
University and served as a fellow in infectious diseases at
Brown University Medical School before becoming director
of health for the State of Rhode Island. DeBuono was named
New York State commissioner of health by Governor George
Pataki in 1995 , becoming the first woman to hold the job.
During her address at Spring Clinical Day, DeBuono said
that the state had balanced cost-cutting with social responsibility in its Health-Care Reform Act of 1996, which deregulated
BY

DON

HEUPEL

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1

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Summer

1

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SIXTIETH

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ALUMNI

hospital rates and created unique funding
pools for graduate medical education and
charity care.
However, she noted, there's a lot more
for state government to accomplish. As a
member of a Republican administration
that is in principle dedicated to reducing
state regulation, DeBuono sounded reluctant to draft legislation to deal with minute
details of health-care delivery.
But legislation to cope with the "growing
pains" of managed care, such as denials of
care and physicians being deselected from
networks without good reason, seems inevitable, she said. DeBuono also cited examples of insurers delaying reimbursing
hospitals for service worth millions of
dollars until the Department of Health
intervened.
"I don't want to have to legislate that,"
she added. "I wish the industry would do it
voluntarily."
The goal is to make sure that medical
decisions are made for medical reasons,
not economic ones.
"The more managed care and indemnity insurance take decisions out of the
hands of providers, the more frustrating it
is for doctors and patients," DeBuono said.
"We've got to fix that problem."
An important step, she said, was the state
Managed Care Omnibus Act of 1996, which
has been praised by the American Medical
Association for protecting providers and
patients. It bans gag orders; ensures that
managed care plans disclose their coverage,
referral, and emergency care policies; allows doctors to appeal deselection; and
establishes a patient grievance procedure.
Legislation alone is unlikely to solve all
the problems. DeBuono's story about the
Whipple procedure grievance shows that
some of the toughest deci ions may continue to be made on a case-by-case basis.
"I still haven't decided what to do ,"
DeBuono confessed about the case. "If anyone has any ideas, let me know." +

B

u

f

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a

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o

Physician

summer

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�SIXTIETH

ANNUAL

ALUMNI

Practicing medicine
under anaged
he thoughts I share with you
today are mainly personal,
and are geared toward our responsibility in patient advocacy and
the preservation of our profession
in managed care.

The failure of managed care
When managed care first came into
being, it is my understanding that it
was supposed to give less expensive
care to people who couldn't afford
conventional insurance. It is hard to argue that the first goalless expensive care-has indeed been achieved. Health-care
premiums have risen at or below the inflation rate for two
years, but most industry experts predict more increases. The
multifactorial reasons for this include:
1. the need ofHMOs to satisfy stockholders after delivery
of low profits last year;
1. the consolidation of HMOs into fewer and larger
entities, eliminating competition and allowing prices to rise;
3. more expensive technology and an aging population;
4. demand from consumers for more access to specialists
and point-of-service plans; and
S. federal and state legislation that make it difficult for
managed care to control costs.
Managed care has also been a resounding failure in
providing coverage to the uninsured and the underinsured.
It is estimated that by the year 2002, the number of uninsured
will reach 45.6 million, up from 39.5 million in 1995.
The health-care reform agenda empowered managed care,
and managed care failed to deliver the goods.
What is quality care?
The most abused and misused phrase of the '90s, in my
opinion, has been "quality care." What exactly is quality
care? Ask any of the four players in health care-employers,
insurers, providers, or patients. Instantly, we have a problem.
Patients and health professionals tend to think differently
about what constitutes quality of care. Patients judge quality
by very personal experiences, such as how long their proBY

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care

vider spends with them, how easy it is to access specialty care,
and the range of health benefits provided.
Professionals, on the other hand, tend to rely on populationbased performance measures, such as outcomes of cancer
treatment over time. Employers concern themselves with
such data as cost, time lost from work, and employee
satisfaction as demonstrated by complaints to their human resources departments. Insurers declare their own
quality measures.
The ational Committee for Quality Assurance ( CQA) ,
the organization set up to measure quality of care given by
managed care plans, has come under attack for not being
independent enough. As of 1996, CQA got 40 percent of its
funding from HMOs. The Health Plan Employer Data and
Information Set (HEDIS) that CQA uses has been widely
criticized by physicians for tallying up easy-to-administer
tests rather than getting at core issues of what constitutes
quality medical care. HEDIS doesn't measure quality: It
measures the number of Pap smears or immunizations given.
To confuse this picture even further, the development of
quality measures has proven to be philosophically contentious, technically difficult, and politically delicate.

Physicians must act
Finally, some answers. This is a perfect place for physicians
to take a leading-edge position by demanding relevance,
objective research, and appropriate application. Physicians
and managed care organizations need to work together to establish treatment guidelines patients can trust. Wide-ranging
collaborative efforts led by academic researchers would be
the most promising in outcomes research and treatment
guidelines. And we must be at the table either individually or
through our subspecialty societies when outcomes data is
analyzed and implemented.
just as we must be willing to accept report cards on our
performance, we must demand more in-depth surveys of
HMOs. Physicians should push for public disclosure and
comparisons of HMOs regarding their performance in treating serious or chronic illnesses, how often and why out-ofplan referrals are denied, and ease of access to specialty care,
among other things.

SNOW

o

WEEKEND

.

Phys

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-

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----- - - - - - - - -- - - -

SIXTIETH

ANNUAL

---

-

---

--

ALUMNI

I must admit that when I think of managed care, I feel like
Albert Finney in the movie Network when he opens his
window and shouts out, "I'm mad as hell and I'm not going to
take it anymore!" In my more rational moments, however, I do
believe that doctors who fight managed care at every turn will
find themselves in a losing battle.
We should take the lead in health-care delivery by admitting
that we are dealing with finite resources. But physicians need to
be a blaring trumpet section in our argument that we are better
at making medical decisions and more compassionate than
utilization review clerks. Doctors must take a stand against
economics driving ethics and insist that ethics drive the economics. While accepting the
principlesofpracticingcosteffective medicine , we
must be able to challenge
certain managed care rules
that we feel compromise
patient care.
While on the topic of
ethics and economics, I am
philosophically opposed to
the concept of capitated
agreements. Simply stated,
I just wasn't raised to be
rewarded for work I haven't
done. Under capitation, if
you manage patients efficiently and effectively you
stand to gain. The potential abuse of this system is
glaringly obvious and extremely frightening. As patient advocates, we should
not allow a system that
poses this kind of potential threat to patient care to gain
momentum. Capitation places providers-already in need of
tort reform-in legally indefensible positions. In potential
errors of omission, it will not take a Perry Mason to ask, "So,
Dr. X, did you stand to gain financially by not ordering testY? "
Yet capitation is here, thriving, and soon I will find myself
practicing within it. However, I hope its prognosis is poor!
Capitation in its pure form, without adequate oversight and
regulation, is a consumer activist's next cause, and in my
opinion, rightfully so.

Hold HMOs responsible
We must encourage regulators, employers, and consumers to
insist on greater public disclosure of HMO financial results.

-

-

-

WEEKEND

George Anders, a Wall Street journal reporter, said it better than I can
in his book Health Against Wealth:
HMOs and the Breakdown of Medical
Trust. Anders commented that the big profits and compensation packages of some HMO industry executives can be
seen as "uncomfortable hypocrisy for an industry that
publicly preaches the virtues of austerity."
o discussion of how physicians practice in any environment would be complete without mentioning the need
for tort reform. In this regard, I mean that HMOs need to
be held accountable for their mistakes. HMOs need to be

"I question
how long I will
be able in
good
conscience o
practtce
economically
driven
me 1c1ne."

subjected to the same malpractice restitution methods that physicians and other
professionals face.
Perhaps it is time for us to renew our commitment to
the professional oath, ethical principles, and ongoing
education process of a vocation that has always been
dedicated to the betterment of mankind.
The practice of medicine is in a state of unrest, which has
the potential to bring out the best or worst in our profession. We must have the courage to speak out against any
system that jeopardizes our legal right and moral obligation to practice good medicine. When historians record
how we responded to these challenging times, it is my hope
that we will be remembered for our commitment to our
patients, our colleagues, and our principles. +

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��with all of tne diseases of. dentistry, bexond dental caries and
tne cracl&lt;s oetween aentistry

ommunities extenaing
Pennsylvania
Alfredo Aaulrre of the Orel
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��Specia
cinic takes
haitosis
senousy
"Some people have joked, 'Maybe you could sell gift
certificates,"' says Mirdza Neiders, D.D.S., M.S., head
of the Breath Disorders Clinic in UB's Department of
Oral Diagnostic Sciences. "Because most of our patients
are referred by another person, like their spouse."
The Breath Disorders Clinic is one
" The best
of six Special Care Clinics that specialdetector
ize in diagnosing and treating dental
or medical difficulties that most pracis still the
titioners don't usually treat. They fill
human
in
the gray areas between medicine
nose."
and dentistry, including psychological and social concerns that affect many Americans.
All kidding aside, halitosis is one such serious
social problem, as evidenced by the millions of
dollars spent in the U.S. and Canada on breath
mints, toothpastes, and mouthwashes. Some people
are so concerned about their breath that they build
their lifestyles around avoiding people. They may be
referred to the clinic by someone close to them, or
else a physician or dentist.
While some cases of halitosis are truly medical,
many can be alleviated relatively easily. The first step
for patients coming to the Breath Disorders Clinic is
for the clinician to determine whether the person
truly has bad breath and, if so, to track down the
origin of the problem.
"The best detector is still the human nose," admits
eiders. "If the person does have bad breath, treatments can then be designed to tackle it. If they don't,
I sometimes refer them to Dr. Gale to help them
overcome their social inhibition."
In most cases, bad breath is caused by anaerobic
bacteria on the surface of the tongue; these bacteria
can simply be scraped away with a flexible, dull
object, such as the edge of a plastic spoon. Prescription antiseptic mouthwash can also be helpful in
some cases. If the odor is being emitted by an infection under an old crown or between teeth, repair of
these defects is the best medicine. +
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�43-year-old
physician takes leave
for his other calling

by CLARE O ' SHEA

"Can you hold on a second? "
DAVE WELDO

'81

PUTS THE PHO

E DOW

and rushes off

again. We had been discussing his neuroanatomy professor at UB, the
intense summer he spent immersed in microbiology and pharmacology,
the way the snow would settle on the evergreen outside his tiny
apartment off Hertel Avenue. But those memories are 15 years old, and
right now Weldon doesn't have much more than 15 minutes for
nostalgia. Voices on the other end of the line are calling him to the floor
of the U.S. House of Representatives. It's time to vote on public housing.

®

Buffalo

Physician

Summer

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�unruffled, quietly picking
up where he left off and
continuing his train of
thought from the House
cloakroom, his refuge between votes. In many ways
he sounds less like a doctor
than, well, a politicianbut Weldon finds a lot of
similarities between the two
vocations.
"The general skills a physician has transfer well into
the political arena," he says.
"My background gave me a
lot of experience in relating
to people, solving problems, and explaining complex issues to people in
terms they can understand."
While Weldon has become
comfortable on Capitol Hill,
he remains committed to
his first calling. "I don't see
myself as a career politician," he says. When he was
elected in 1994, he pledged
to honor an eight-year term
limit. "I definitely identify
myself as a doctor-a
doctor temporarily on leave
to serve Congress."
Being on leave has only
meant shifting to a higher
gear, however. life in Congress,
says
- - - - - - - - - - - - - - - - - - - - --t"lm--- Weldon, is "like

These days Weldon is better known
as "Honorable" than "Doctor." For the
being an intern
"The general skills a physician
past three years Weldon, a 1981 graduyear-round." In a
has transfer well into the political
ate of the UB School of Medicine and
sense, Weldon
Biomedical Sciences, has been serving arena. My background gave me a lot of
has been running
as a Republican representative. Instead
at that pace since
experience in relating to people,
oflooking after patients, he's been lookhe left his home
ing after the needs of Florida's 15th
on long Island
solving problems, and explaining
Congressional District. Instead of mediand enrolled in
complex issues to people in
cal cases, he's been caught up in welfare
the accelerated
reform, balancing the federal budget,
terms they can understand."
medical program
and school-choice legislation.
at UB. He had
"Okay, now where was I? I was in the accelerated program
planned to work his way through medical school, but when
at UB, and ... ." We'll be interrupted five times by the end of
he realized how demanding the program would be he applied
our conversation, but the 43-year-old congressman remains
for an Army Health Professions scholarship. Then he got

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�''I'm not expecting heaven on earth-there will
still be a lot more worl&lt; to do when I leave.''
Weldon also serves on the House Science Committee and
engaged to ancy, whom he'd met when they were both
the House Banking and Financial Services Committee. And
students at the State University of New York at Stony Brook.
his commitment to health-care issues has not been forgotten.
"l went through this grueling summer curriculum, took my
finals, then ran back to Long Island, got married , and went on
"We did pass important health insurance reform in the last
Congress that will restrict the ability of insurance companies
my honeymoon, " he says. "It was a whirlwind, but those were
wonderful years. I was newly married , studying like crazy, and
to exclude people because of preexisting conditions," Weldon
notes. "I was very pleased with that. But I think there's a lot
working with some of the finest people I've ever known. "
Weldon graduated from UB in 1981 and spent the next
more that can be done to make insurance more accessible and
three years at the Letterman Army Medical Center in San
affordable. l'd also like to see medical malpractice reform,
Francisco, where he completed his internship and residency
although the President has been an adamant opponent of it. "
Because Weldon
in internal medicine. He
and his family spend
was then assigned to a
part of every month
three-year tour of duty at
"I began to become concerned with what I
in Washington , it is
Winn Army Community
saw as a bad direction that we were
impossible for him to
Hospital in Fort Stewart,
GA. The highlight? Workhave regular patients.
heading in as a nation. I was particularly
ing with General orman
But he continues to
disturbed by the high degree of family
Schwarzkopf.
see patients at the
"He was the division
Melbourne medical
breakdown and the general erosion
commander when I got
group 's Saturday
of traditional values."
there ," Weldon recalls ,
walk-in clinic. He
"and I was his wife's
also is on call on occasional weekends at a community hospital in Melbourne.
doctor and a good friend of his aide-de-camp. "
"l really did like practicing medicine, and I had reservaBy the end of his army duty in 1987, Weldon and his wife
tions about giving it up. That played a strong role in my
were in love with the South. They moved to Melbourne , FL,
decision to serve only eight years. My plan is to return to
where Weldon was in private practice only a few years when he
started thinking seriously about getting involved in politics.
private practice in 2002. !look forward to that. The pace is so
"I began to become concerned with what I saw as a bad
much slower than this-can you hold on a second'"
direction that we were heading in as a nation ," he explains. "I
Weldon puts the phone down again and goes off to cast his
was particularly disturbed by the high degree of family breakvote against an amendment (proposed by Rep. joseph
down and the general erosion of traditional values. And I
Kennedy, D-Mass .) to a bill to repeal the United States
thought it was terrible that our congressional leaders in WashHousing Act of 1937 and deregulate the public housing
ington were just borrowing money year in and year out. "
program. "These are amendments that usually just make it
easier for people to get public housing, " Weldon says. "That's
First he threw his support behind local candidates whose
generally the trend. Mr. Kennedy has a vision that's very
vision he shared. Then one day in 1993, a colleague suggested
that Weldon would make a better congressman than any of much opposite to what the Republican majority vision is. "
the candidates running for election the next year. Coupled
Welfare reform and a savings of $50 billion in government
with his concern about the Clinton health-care plan-like
spending are among the initiatives that Weldon sees as signals
of positive change since he went to Washington. ln the next
many physicians, Weldon is skeptical about the federal
five years, he hopes to contribute to a crackdown on crime and
government's ability to run the health-care system
drug abuse and to continue to push for a smaller federal
efficiently-that suggestion "pushed me over the edge,"
government and lower levels of taxes. "The process of change
he says. Weldon won the election in 1994 and was reelected
has been slow," he says, "but I think we're making headway. "
to a second term in 1996.
And if the world hasn't changed enough by 2002, will
Since his district includes the Kennedy Space Center,
Weldon be able to give up politics?
Weldon devotes substantial time to space issues. His medical
''I'm not expecting heaven on earth-there will still be a lot
expertise has proved useful here, as well. "''m a big supporter
more work to do when I leave," Weldon says. "But l don't
of the space program," he says, "and there's a lot of exciting
think l could totally walk away from politics after this. lt's
science research that is performed on the shuttle, like
gotten into my blood." +
microgravity research. "

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�Sandra A. Block Internal
Medicine, UB Graduate Medical
Dental Education Consortium,
Buffalo , Y

Match Day 1997

Adrienne D. Bonham Obstetrics
and Gynecology, University of

wo-thirds ofUB's graduating medical students were placed

Rochester/Strong Memorial
Hospital , Rochester, Y

in primary care residencies in this spring's Match Day.
The

Timothy P. Braatz Internal
Medicine (prelim ), University of
Maryland , Baltimore, MD;
Radiology-Diagnostic , University
of Maryland , Baltimore, MD

ational Residency Matching Program results

were announced March 19 by associate dean Dennis

Angela M. Camasto
Pediatrics, University
Hospitals of Cleveland,
' Cleveland, OH

adler. Eighty-six percent of the students got their first,
second, or third choice of placements.
Almost one-third will stay in Buffalo to train in the Graduate Medical Dental
Education Consortium, while 48 percent will go out of state.
In the primary care specialties, 28 students were placed in internal medicine, 2 7
in pediatrics, 21 in family medicine, and 7 in medicine-pediatrics. This is the first
year that ew York State has considered obstetrics-gynecology one of the primary
care specialties. Fourteen students were matched to OB-GY

residencies.

"We're very pleased with the outcome of the match, especially with respect to
the number of students who chose residencies in primary care,"

adler said.

"We've worked very hard to achieve this goal."
Jared C. Barlow lntemal Medtcine
(prelim ), ew Rochelle Hospital ,
New Rochelle , NY; Anesthesiology,
Mount Sinai Hospital , ew York ,
NY
Drew H. Barzman Psychiatry,
Duke University Medical Center,
Durham , NC

Juan P. Abonla Pediatrics , UB
Graduate Medical Dental
Education Consortium, Buffalo,
NY

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Edward L. Chan Pediatrics, UB
Graduate Medical Dental
Education Consortium, Buffalo,
y

Alexander W. Chen Medicine/
Pediatrics, Duke University Medical
Center, Durham, C
Kristen M. Chimileskl Pediatrics,
University of Chicago Hospital,
Chicago, IL
Ronlka D. Choudhary Family
Practi ce, Highland Hospital of
Rochester, Rochester, NY

Joseph L. Chow Family Practice,
Highland Hospital of Rochester,
Rochester, NY

Gonzalo M. Bearman Intemal
Medicine, UB Graduate Medical
Dental Education Consortium,
Buffalo, Y

Ravl K. Desai Internal Medicine,
UB Graduate Medical Dental
Education Consortium , Buffalo,
NY

Terl Beers Obstetrics and
Gyn ecology, UB Graduate Medical

Gregory DIFrancesco Emergency
Medicine, UB Graduate Medical
Dental Education Consortium ,
Buffalo, Y

Cassann N. Blake Surgery , SU Y
Health Science Center, Brooklyn,
y

m

Patricia A. Cawley Pediatrics,
Morristown Memorial Hospital ,
Morristown , J

Catherine C. Costello Pediatrics ,
Albert Einstein College of
Medicine!Montefiore Medical
Center, Bronx, NY

Altagrace Belmar Pediatrics
(primary), Albert Einstein College
of Medicine/Montefiore Medical
Center, Bronx, NY

Sharon Baratz Internal Medicine,
George Washington University,
Washington , DC

Jason M. Andrus Psychiatry,
University of Hawaii , Honolulu , HI

y

Kathleen M. Batt Family
Practice, Halifax Medical Center,
Daytona, FL

Dental Education Consortium ,
Buffalo, NY

Jean S. Bae Psychiatry, University
of Wisconsin Hospital and Clinics,
Madison , WI

Jeffrey A. Cassidy Surgery
(prelim), UB Graduate Medical
Dental Education Consortium ,
Buffalo, Y; Orthopedics, UB
Graduate Medical Dental
Education Consortium, Buffalo,

e

9

9

Andrew Dmytrljuk lttternal
Medicine, George Washington
University, Washington , DC
Jacqueline A. Dombrowski
Medicine/Pediatrics , UB Graduate
Medical Dental Education
Consortium, Buffalo, Y

�Morris P. Elevado Internal
Medicine, University of Massachusetts Medical Center, Worcester,
MA

Clarlsa R. Gracia Obstetrics and
Gynecology, Hospital of the
University of Pennsylvania,
Philadelphia, PA

Paul J. Kerner Orthopedics,
Allegheny University, Central City,
PA

Thomas R. Elmer Internal

Matthew J. Gutierrez Internal

Medicine (prelim), Alton Ochsner
Medical Foundation, New Orleans,
LA; Ophthalmology, Louisiana tate
University Eye Center, ew
Orleans, LA

Medicine, University of Vermont!
Fletcher Allen Health Care,
Burlington, VT

(prelim), University Hospital, Stony
Brook, Y; Radiology-Diagnostic,
SU Y Health Science Center,
Brooklyn, Y

Paul A. Guttuso Family Practice,

Peter W . Kim Internal Medicine,

St. Mary Hospital, Lubbock, TX

Simone P. Elvey Internal Medicine

Taj A. Hadee Pediatrics,

Medical College of Virginia,
Richmond, VA

(prelim), UB Graduate Medical
Dental Education Consortium,
Buffalo, NY; Radiology-Diagnostic,
University of Rochester/Strong
Memorial Hospital, Rochester, NY

Children's Memorial Hospital,
Chicago, IL

Peter S. Ercollno Pediatrics,

Asra Khan Internal Medicine

Randy S. Fagin Surgery (prelim),

UB Graduate Medical Dental
Education Consortium, Buffalo,

Y

Pamela R. Haefner Pediatrics,

Electra C. Martin Emergency
Mediciue, SUNY Health Science
Center, yracuse, Y

and Gynecology, UB Graduate
Medical Dental Education
Consortium, Buffalo, Y

Andrew Klapper Plastic Surgery,

Paul J. Mason Orthopedics, Henry

Eric J. Hanauer Internal Medicine

Benjamin 0 . Koenig Emergency
Medicine, William Beaumont
Hospital , Royal Oak, Ml

Janine M. McAssy Internal

Suchltra Koneru Family Practice,

M. Angela Mclellan Obstetrics
and Gynecology, UB Graduate
Medical Dental Education
Consortium, Buffalo, Y

ew York University Medial
Center, New York, Y

Jennifer T. Hanauer Obstetrics

(prelim), Albert Einstein College of
Medicine!Montefiore Medical
Center, Bronx, Y; eurosurgery,
Albert Einstein College of
Medicine!Montefiore Medical
Center, Bronx, NY

and Gynecology, Rochester General
Hospital, Rochester, NY

James B. Gaul Medicine/Pediatrics,

University of Minnesota Hospital
and Clinic, Minneapolis, M

Agnes A. Gelder Family Practice,

iagara Falls Memorial Medical
Center, Niagara Falls, Y
Jennifer P. Gennuso Pediatrics,

Kathleen P. Gillan-Lundgren

Pediatrics, Children's National
Medical Center, Washington, DC

Louisiana State University School
of Medicine, Shreveport, LA

Armond M. Lapine Internal
Medicine, niversity of Utah
Affiliated Hospitals, Salt Lake City,
T

Peter M. McNeela Family

Practice, Hamot Medical Center,
Erie, PA
Peter S. McQulller Anesthesiology

UB Graduate Medical Dental
Education Consortium, Buffalo,
NY

Manal Hegazy Surgery,

ew
ew Rochelle,

y

Research, Buffalo, NY
Lisa M . Mendonza Family

Practice, UB Graduate Medical
Dental Education Consortium
Buffalo, NY

Janice M . Lee Internal Medicine,

Wenchun Hsu Emergency
Mediciue, Emory University chool
of Medicine, Atlanta, GA

t. Louis University School of
Medicine, t. Louis, MO

Michael D. Merrill Internal

Jeffrey M . Legrett Internal

Medicine (primary), UB Graduate
Medical Dental Education
Consortium, Buffalo, NY

Mediciue, UB Graduate Medical
Dental Education Consortium,
Buffalo, NY

Daniel C. Metrick lntemal
Medicine, Mount Auburn Ho pita!,
Cambridge, MA

Kenneth A. Levey Obstetrics and

Gynecology, George Washington
University, Washington, DC

Claudia Jaramillo luternal

Medicine (primary) , UB Graduate
Medical Dental Education
Consortium, Buffalo, Y

Jennifer A. Meyer Pediatrics,

Timothy N. Llesching Internal

y

Akron General Medical Center/
EOUCOM, Akron , OH;
Ophthalmology, Case Western
Reserve University, Cleveland, OH

Joseph F. Lopes Surgery (prelim),

Dartmouth-Hitchcock, Lebanon,
NH; Urology, DartmouthHitchcock, Lebanon , NH

Medicine, UB Graduate Medical
Dental Education Consortium,
Buffalo, NY

Loren S. Kane Internal Medicine,

Andre L. Lopez Family Practice,
University of Medicine East
Carolina-Pitt County Memorial
Hospital , Greenville, C

Stephan J. Mllback Family
Practice, aval Hospital, Camp
Pendleton , CA

Medical University of South
Carolina, Charleston, SC
Jeannie Kao Physical Medicil1e

and Rehabilitation, William
Beaumont Hospital, Royal Oak,
Ml

0

Alex Mompoint Internal Medicin e

(prelim) , Sisters of Charity
Hospital , Buffalo, Y; Physical
Medicine and Rehabilitation,
University of Texas outhwestern
Medical Center, Dallas, TX

UB Graduate Medical Dental
Education Consortium, Buffalo,
y

Iuternal Medicine, UB
Graduate Medical Dental
Education Consortium,
Buffalo, Y

B

Lori A . Michael Emergency

Andrew J. Luisi Internal Mediciue,

Brian M . Karaszewski

B

Graduate Medical Dental
Education Consortium, Buffalo,

Medicine, Deaconess Hospital,
Boston, MA

Thomas J. Joly Transitional,

Y

Mediciue, University Health Center,
Pittsburgh, PA

Frank M . Lee Emergency Medicine,

Obstetrics and Gynecolog) , Our
Lady of Mercy Medical Center,
Bronx, NY

(prelim), UB Graduate Medical
Dental Education Consortium,
Buffalo, NY

UB Graduate Medical Dental
Education Consortium, Buffalo,

Thomas E. Hansen Orthopedics,

Rochelle Hospital,

Ford Health Science Center,
Detroit, Ml

University of Maryland, Baltimore,
MD

Ayanna Angela L. James

Jennifer L. Geiger Surgery

Pathology, UB Graduate Medical
Dental Education Consortium,
Buffalo, Y

University of Wisconsin/St. Mary's
Medical Center, Madison, WI

Eric I. Finkelstein Surgery

University of Rochester/Strong
Memorial Hospital, Rochester, NY

Dori R. Marshaii-Hobika

Gregg E. Kissel Family Practice,

Lorna Linda University, Lorna
Linda, CA

Medicine, UB Graduate Medical
Dental Education Consortium,
Buffalo, NY

David R. Frels Internal Medicine,

Pediatrics,
University Health Center,
Pittsburgh, PA

Akron City HospitaVNEO COM,
Akron, OH

(prelim), University of Rochester/
Strong Memorial Hospital ,
Rochester, Y; Neurology,
niversity of Rochester/Strong
Memorial Hospital, Rochester, Y

Michael A. Filice Emergency

Alexander Marcus

Regina Y. Kim Family Practice,

Sabrina R. Hammett Obstetrics

University of orth Carolina
Hospital, Chapel Hill , C

Paul M. Maggio

Surgery, Rhode
Island Hospi tall
Brown University,
Providence, Rl

Cozzette Lyons Internal Medicine,

University Hospitals of Cleveland,
Cleveland, OH

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�Jonathan A. Morgan Internal
Medicine (prelim), Long Island
jewish Medical Center, ew Hyde
Park, NY; Radiology-Diagnostic,
Thomas jefferson University,
Philadelphia, PA

Christopher M. Pieczonka
Surgery (prelim) , UB Graduate
Medical Dental Education
Consortium, Buffalo, NY; Urology,
UB Graduate Medical Dental
Education Consortium, Buffalo,

Shrini T. Mukkamala Surgery
(prelim), B Graduate Medical
Dental Education Consortium,
Buffalo, Y

David M. Pllati Surgery,
University of North Carolina
Hospital, Chapel Hill , C

Tracey L. O'Connor Intemal
Medicine, University of Rochester/
Strong Memorial Hospital,
Rochester, NY

Mount Sinai, Flushing, NY

Gina L. Parlato Family Practice,
orth Colorado Medical Center,
Greeley, CO
Emmanuella Paul Family
Practice, Emory University School
of Medicine, Atlanta, GA

Christian W. Rochoii intemal
Medicine (prelim), niversity of
Vermont/Fletcher Allen Health
Care, Burlington, VT

Philip S. Piasecki Intemal
Medicine (prelim), Sisters of

Paul Rosen Pediatrics (pri mmy),
Mount Sinai Hospital, ew York,

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Matthew Smith, D.D.S. Surgery
(prelim), B Graduate Medical
Dental Education Consortium,
Buffalo, Y
Gavin N. Somersel Obstetrics and
Gynecology, Albany Medical Center

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Matthew Taberski Internal
Medicine, Hospital of the niversity
of Pennsylvania, Philadelphia, PA

Evan S. Taragano Pediatrics,
University Health Center,
Pittsburgh, PA
Andrea L. Torsone Obstetrics and
Gynecolog), University of North
Carolina Hospital, Chapel Hill, NC
Meryl Y. Tucker Obstetrics and
Gynecology, UB Graduate Medical
Dental Education Consortium,
Buffalo, NY

Usha Vaidyanathan Internal
Medicine, University Hospitals of
Cleveland, Cleveland, OH
Joseph H. Wandass Ill Medicine/
Pediatrics, UB Graduate Medical
Dental Education Consortium,
Buffalo, Y
John J. Welch Pediatrics,
Georgetown University Hospital,
Washington, DC
Dayo N. Wilson Medicine/
Pediatrics, B Graduate Medical
Dental Education Consortium,
Buffalo, Y

Noelle M. Stevens Family
Practice, SU Y Health Science

Danielle A. Woodall Internal
Medicine, Albert Einstein College of

Center at Syracuse/St. joseph's
Hospital Health Center, Syracuse,
y

Sarah K. Storm Pediatrics, North
Shore University Hospital,
Manhasset, Y
Gary A. Styn Family Practice, B
Graduate Medical Dental Education
Consortium, Buffalo, NY

m

Julie A. Szumigala Obstetrics and
Gynecology, UB Graduate Medical
Dental Education Consortium,
Buffalo, NY

louise Z. Spierre Pediatrics,
University of Cincinnati Hospital ,
Cincinnati, OH

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Nicole L. Symons Family Practice,
University of Medicine East
Carolina-Pitt County Memorial
Hospital , Greenville, C

William M. Wind StJrgery
(prelim), UB Graduate Medical
Dental Education Consortium,
Buffalo, Y; Orthopedics, UB
Graduate Medical Dental Education
Consortium, Buffalo, Y

Hospital, Albany,

Vitaly Raykhman Surgery
(preli m), UB Graduate Medical
Dental Education Consortium,
Buffalo, Y; Umlog), B Graduate
Medical Dental Education
Consortium, Buffalo, Y

Maryann M. Parietti-Scharf
Family Practice, Highland Hospital
of Rochester, Rochester, Y

u

Monica J. Simons Obstetrics and
Gynecology, Queens Hospital!

Pamela P. Rath Transitional,
Hennepin County Medical Center,
Minneapolis, M ; Ophthalmology,
University of Minnesota, Minneapolis, M

John Panagiotopoulos Intemal
Medicine, Winthrop-University
Hospital , Mineola, Y

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Jimmy Y. Sim Pediatrics, Thomas
jefferson University/Dupont
Institute, Philadelphia, PA

Jennifer M. Ragi Intemal
Medicine, Hospital of the University
of Pennsylvania, Philadelphia, PA

lesley A. Orman Pediatrics,
Eastern Virginia Medical School,
orfolk, VA

Charity Hospital , Buffalo,

Charles M. Severin, Ph.D.
faculty, Department of Anatomy
and Cell Biology, UB Graduate
Medical Dental Education
Consortium, Buffalo, Y

John C. Radford Emergency
Medicine, UB Graduate Medical
Dental Education Consortium,
Buffalo, NY

Medical Center, Merced , CA

Jennifer F. Sussal, M.P.H.
Pediatric Psychiatry, Albert Einstein
College of Medicine/Montefiore
Medical Center, Bronx, Y

Craig M. Senzon Intenwl
Medicine (prelim), Beth Israel
Medical Center, New York, Y;
Neurology, Albert Emstein Medical
Center, Bronx, NY

Bobbie l . Pustelny Surgery
(preli m), University of California at
Los Angeles, Los Angeles, CA

Christopher M. Occhino Family
Practice, Merced Community

Noah D. Sabin Surgery
(prelim), Abington
Memorial Hospital,
Abington, PA; RadiologyDiagnostic, Albert Einstein
College of Medicine(Jacobi
Medical Center, Bronx, Y

y

Catherine F. Przystal Medicine/
Pediatrics, University of Rochester/
Strong Memorial Hospital,
Rochester, Y

David J. Novak Internal Medicine
(prelim), Georgetown University
Hospital , Washington, DC

Paniti Sukumvanich Obstetrics
and Gynecology, niversity Health
Center, Pittsburgh, PA

Tami S. Seaman Family Practice,
UB Graduate Medical Dental
Education Consortium, Buffalo,

Aisha K. Prim Pediatrics,
Children's ational Medical
Center, Washington, DC

Manyan Ng Pediatrics, Thomas
jefferson University/Dupont
Institute, Philadelphia, PA

James J. Runfola Family
Practice, West jersey Health
System, Trenton, J

Patrick V. Scott, D.D.S. Surgery
(prelim), UB G•aduate Medical
Dental Education Consortium,
Buffalo, Y

V. Chowdry Pinnameneni
Intemal Medicine (prelim), New
York Methodist Hospital ,
Brooklyn. Y

Gerardo Negron Internal
Medicine, UB Graduate Medical
Dental Education Consortium,
Buffalo, Y

Lisa S. Sufrin Pediatrics, University
of Cincinnati Hospital , Cincinnati,
OH

Thomas E. Schenk
Pediatrics, UB Graduate
Medical Dental Education
Consortium, Buffalo, Y

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James P. Murray Medicine/
Pediatrics, University of Texas
Medical School, Houston , TX

Mary E. Ross Pediatrics, St.
Louis Children's Hospital ,
St. Louis, MO

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Medicine(Jacobi Medical Center,
Bronx, NY

Denise C. Woodall Pediatrics,
Eastern Virginia Medical School,
orfolk , VA
Carolyn M. Young Psychiatry, UB
Graduate Medical Dental Education
Consortium, Buffalo, Y

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Rettred surgery professor dies
BY

WORTHINGTON

G .

SCHENK

n September 4, 1996, surgery lost
an outstanding leader with the death
of john D. Stewart, M.D.
Stewart earned a B.A. from the
University of Virginia and graduated cum laude from Harvard Medical School in 1928. He and
Henrietta Rhees were married
in 1937 and had two daughters
and one son. Their son, David,
became a surgeon, but tragically, died quite young of undiagnosed overwhelming sepsis.
Stewart completed an internship at the Huntington Memorial Hospital and a residency at
Massachusetts General Hospital. He did research and further

JR . ,

M . D .

work at Massachusetts General and
Harvard before being appointed professor
of surgery at UB and chief of surgery at the
E. ]. Meyer Hospital (now Erie County
Medical Center).
In 1943, he was commissioned a major in the U.S. Army Medical Corps and a year later
was promoted to lieutenant colonel. He served on
several national research
committees, including the
surgery section of the ationa! Institutes of Health.
After serving a term on the
American Board of Surgery, he became its chair
in 1956. Stewart also

Nobelist dies at 94
ir john Carew Eccles, a

abel Prize-winning neuro-

physiologist and a former member of the UB faculty, died
in May at his home in Switzerland, the

ew York Times

has reported. He was 94.
In 1963, Eccles shared the obel Prize
for Medicine or Physiology with Alan
Hodgkin and Andrew Huxley for describing the electrochemical communication
system between nerve cells. Eccles showed
that excited nerve cells release a substance (acetylcholine) that enlarges pores
in a neighboring cell's membrane, allowing positively charged sodium ions to
enter the cell, reverse the polarity of the
electric charge in the cell, and transmit
the nerve impulse.
He also found that in other types of
synapses, the excited nerve cell induces
the neighboring cell to discharge potas-

sium ions, which reinforces
its existing polarity and inhibits the transmission of the
nerve impulse.
Eccles was the author of a number of
books, including The Physiology of erve
Cells (1957), The Inhibitory Pathways of
the Central ervous System (1969) , The
Understanding of the Brain (1973), and
The Human Psyche (1980).
Born in Melbourne, Australia , Eccles
earned his bachelor's and medical degrees
from Melbourne University, and his
master's and doctorate from Oxford
University under a Rhodes scholarship.

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served as president of the American Surgical Association and was active in many
other professional groups.
His interests were not limited to surgery. The family kept cattle and working
horses on ranches in South Carolina and
Florida.
In 1965,john retired from his medical
school and hospital positions and moved
to Boca Raton, Fl. During his professional career, he trained 20 surgeons,
most of whom became chief surgeon at
their institutions. Few surgeons made
the breadth of contributions to the profession as did john D. Stewart. +
Worthmgwn G. Schenh jr., trai ned with Dr. Stewart and later
succeeded him as ch1ej of surgery at E.). Meyer Hosp1tal.

He conducted the research that led to the obel
in the 1950s while at the
john Curtin School of
Medical Research of the
Australian ational University in Canberra. Eccles
was knighted by Queen
Elizabeth II in 1958. Other
honors included membership in the Pontifical
Academy of Sciences and
a four-year term as president of the Australian Academy of Science.
He and his first wife, Irene, had nine
children. In 1966, Eccles came to the U.S.
to head the American Medical
Association's Institute for Biomedical Research in Chicago. Two years later, he
moved to Buffalo to direct UB's Center for
theStudyof eurobiology. He was named
a SU Y Distinguished Professor in 1975.
After his retirement in 1975, Eccles
and his second wife, Helena, settled in
Switzerland. +

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Morin appointed chair of pediatrics
rederick C. Morin III, M.D.,
has been appointed chair of
UB's Department of Pediatrics after serving as interim
chair for a year.
A UB professor of both pediatrics
and physiology, Morin was also
appointed pediatrician-in-chief at
Children's Hospital of Buffalo. He has
been chief of the hospital's Division
ofNeonatalogy, which is internationally recognized for its research on
treatments for lung failure, including

surfactant replacement
therapy, inhaled nitric
oxide, and liquid
ventilation.
Morin succeeds
F. Bruder Stapleton,
M.D., who is now chair
of pediatrics at the University of Washington.
After earning his
M.D. at Yale University, Morin completed
his residency at
Stanford University
and held a research

FREDERICK

C

MORIN

Ill

fellowship in neonatalogy at the Cardiovascular Research
Institute of the University of California
at San Francisco. He
directed the Intensive
Care ursery at the
University of Rochester before joining the
UB faculty in 1986.
He is board certified
in both pediatrics and
peri nata 1/neona ta 1
medicine. +

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�COMMENI
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Commencement ceremony honors cancer researcher
Internationally
hnown
cancer
researcher
James F. Holland, M.D., was awarded a State University of ew York honorary
doctorate in science at the 151st commencement of the UB School of Medicine and
Biomedical Sciences on May 11.
Holland , whose work helped shape modern treatments for
leukemia and other cancers , also delivered the annual D. W.
Harrington Lecture on May 12, on the topic of "The Search for
HMTV, Human Mammary Tumor Virus."
Commencement ceremonies were held in the Center
for the Arts on the UB orth Campus. SUNY Trustee
Edward . elson conferred the honorary degree on
Holland.
One hundred forty-six students received their M.D.s
during the ceremony, and 37 received Ph.D.s. Four
received M.D./Ph.D.s. The ceremony served as the
conclusion of the university's 18-month sesquicentennial celebration.
Holland, CU Y Distinguished Professor
and chief of the Division of eoplastic Diseases at
Mount Sinai School of Medicine , served as chief of medicine at Roswell
Park Cancer Institute for more than 20 years.
A graduate of Princeton University and Columbia University College
of Physicians and Surgeons, he spent a year at the
ational Cancer Institute before coming to UB and
Roswell Park Cancer Institute in 1954. He was
named chief of medicine at Roswell in 1956, serving until 1973. During much of that time , he also
served as director of Roswell's Cancer Clinical
Research Center and became a research professor
of medicine at UB.
In 1972, Holland received the prestigious
Lasker Award for his work in chemotherapy. +

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liCE ME NT

On with joy to new challenges: Twin sisters Drs.
Danielle and Denise Woodall

(center); Dr. joseph

Lopes with daughter Olivia (top,

page 18); UB

President William Greiner hooding, then congratulating, Dr. james Holland (below, page 18); Interim
Dean john Wright, presiding (top,

page 19); Dr. Lisa

Mendonza with family friends (above); Dr. Regina
Kim signing the Book of Physicians (immediate left);
and Class Speaker Dr. Charles Severin (below).

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Aword from the director of development
BY

LINDA

J .

CORDER.

PH . D. ,

C.F.R.E .

n this issue of the Buffalo Physician, the school honors
and thanks members of the james Platt White Society.
Several times since becoming a development officer in
the School of Medicine and Biomedical Sciences, I have
been asked about the history and evolution of this
honorary recognition organization. The short answer is,
it provides a vehicle to thank those who generously contribute their personal resources to enhance and advance the
School of Medicine and Biomedical Sciences.
Each donor decides where his or her gift will go. Many give
to the school's General Fund, which is disbursed at the
discretion of the dean. It is not an exaggeration to say that the
General Fund is the most important current gift fund. The
caliber of our faculty continues to increase, in part, because
of the flexibility this fund provides in support of searches
and faculty dt.velopment. Other uses for the fund include
recruiting promising students, supporting the minority
high school research apprentice program, and underwriting the Medical Scientist Training Program seminar series.
Some donors choose to designate their gifts
for endowed funds, including endowed scholarships and endowed faculty chairs. Others make
gifts to special projects, such as UB's euroanatomy Museum, or to departmental funds,
which are disbursed at the discretion of the
department chair for such uses as research seed
money or student medical association activities.
Gifts to any of these funds-as well as
annuities, charitable trusts, or bequestsqualify a donor for membership in the james
Platt White Society.
The society offers two types of recognition:
annual and lifetime. An annual gift of $1,000
or more results in a year's membership in the
society. An individual or a couple is granted
lifetime membership in the Founders' Circle
of the society when cumulative contributions
reach $50,000. Recognition in the james Platt
White Society confers recognition in the
University's President's Associates (annual)
and University Founders (lifetime) honorary
organizations.
When the james Platt White Society was
established in 1986, memberships went to

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those who donated $10,000 payable over a period of ten years
to any fund that benefited the school. Larger gifts guaranteed
recognition for a specified number of years. A few "special
members" are still recognized, due to those early agreements.
Several years ago, the recognition categories were changed
to the current annual and lifetime memberships. The category
"Special Membership" is no longer offered, and will expire for
current members at the end of 1999. The recognition category
"In Memoriam" was added to recognize those whose thoughtful foresight included arranging major bequests or gifts from
testamentary trusts for the school's enhancement.
Individuals and couples who support the medical school at
an outstanding level are seen as its closest friends, and so they
receive additional information throughout the year, invitations to certain medical school and university events, and
special recognition by the school. Best of all, this is an open
and expanding group. The more "best friends" the school has,
the more excellent it becomes. All are welcome to contribute
and be recognized for their support.
The entry level for the society has never
been raised. In fact, it has actually been lowered for recent graduates. "Graduates of the
Last Decade" (GOLD) are recognized for annual contributions of only $500 or more. The
Executive Committee wants to encourage all
medical alumni, and especially the GOLD
graduates, to support their school at a level
commensurate with their resources.
We are deeply appreciative of all gifts to the
medical school, especially those that have the
potential to make a transforming difference in
the quality of medical education and residency training offered at UB.
I invite you to read through the roster of
members that follows, and to thank your friends
and colleagues listed there for their outstanding support. If you are not yet in this group,
please consider increasing your contributions
to the school. The executive committee would
like to see this honorary group double in size
by the end of the century.+
Linda). Corder became the direcror of development for the School of
Med1cine and Biomedical Sciences this year. She had previously
sen·cd the school as major gifts coordinaror.

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Dean ' s Circle

james

Generous gifts of $25,000 to $49,999
qualify individuals or couples as
members of the Dean's Circle.

Platt
White
Society

Dr. Kenneth M. and Mrs. joan
Alford

Chair

Buffalo, NY
Dr. Charles D. and Mrs. Mary
Bauer
Byron A. Genner Ill, M.D.

Williamsville, NY

Potomac, MD

I

Founders ' Circle

Individuals or couples whose
cumulative lifetime contributions
total $50,000, or whose
irrevocable deferred gifts total
$100,000 or more, are honored
as permanent members of the
Founders' Circle. Their names
are also repeated in an annual
category, at the appropriate level,
in any year that they make a new
gift to the School of Medicine
and Biomedical Sciences.

Dr. Elizabeth P. Olmsted Ross

Buffalo,

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Cheste1jield, MO

Orchard Park, NY

Dr. Orvan W. Hess

Dr. Richard B. and Mrs. Ellen
Narins

North Haven, CT
Dr. Richard B. and Mrs. Ellen B.
arins

Williamsville, NY
Philip B. Wels, M.D., and Mrs.
Elayne Wels

Eggertsville, NY

Buffalo, NY

I

Dr. George M. Ellis Jr. and Mrs.
Kelly Ellis

Connersville, IN
Lakeview, NY
Mrs. Catherine Fix

Martinsburg, WV
Dr. Thomas F. Frawley

Chesterfield, MO

p

h

Annual Members

Individuals or couples whose
annual gifts total $1,000 or more
are honored in the year the gift
is made, at the level indicated by
the total amount of contributions made during the period
specified. The following lists
recognize this year's annual
members, some of whom are
also honored as members of the
Founders' Circle.

Mrs. Grant (Evelyn) Fisher

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Circle

Gifts of $5,000 to $9,999 are given
due recognition in the Professors'
Circle. Central to a great university
is a strong faculty. Likewise, central
to the future of our school is the
dedication of a cadre of supporters
within the Professors' Circle.

Miss Thelma Sanes

Dr. Kenneth H. Eckhert Sr. and
Mrs. Marjorie Eckhert

Dr. Thomas]. Kufel

Marilla,

Y

Dr. Charles]. McAllister
Clearwater, FL

Buffalo, NY

I Scholars '

Circle

One strength of an outstanding
institution is the caliber of those
who study there. Scholars within
the james Platt White Society
have made gifts to the school
totaling $1,000 to $2,499 during
the past year. These marked
with an asterisk(*) are young
scholars, graduates of the past
decade who qualified with gifts
of $500 to $999.
Dr. Bruce M. Abramowitz

Glenview, IL
Dr. Kenneth Z. Altshuler

Dallas, TX
Dr. Richard Ament

I Professors '

Buffalo, NY

Providence, R1

o

Longboat, FL

Dr. Elizabeth P. Olmsted Ross

Snyder, NY

l

Dr. Benjamin E. Obletz

Hilton Head Island, SC

Dr. Willard and Mrs. Clarice
Bernhoft

a

East Aurora, NY

Dr. Albert C. and Mrs. Linda
Rekate

Y

Chairs ' Circle

Dr. Thomas F. Frawley

Richard]. Nagel, M.D. and Mrs.
Florence Nagel

Dr. joseph and Mrs. Helene
Chazan

Y

just as a department chair earns
recognition for leadership of an
academic program, donors who
make leadership gifts in the range
of $10,000 to $24,999 are given
special recognition by the james
Platt White Society.

East Aurora, NY

Williamsville,

Dr. joel M. Bernstein

Dr. Richard W. Munschauer

Dr. Eugene R. and Mrs. june A.
Mindel!

Dr. Charles D. and Mrs. Mary
Bauer

f

Dr. Thomas]. and Mrs. Barbara
L. Guttuso

Mrs. GraceS. Mabie
Orlando, FL

Buffalo, NY

f

Buffalo, NY

New York, NY

Dr. Kenneth M. and Mrs. joan
Alford

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Buffalo, NY

Mrs. Morris Lamer

Williamsville, NY

B

Dr. Eugene R. and Mrs. June A.
Mindel!

East Amherst, NY

Mrs. june M. Alker

Circle

Fellows within the school are
recognized for the added depth
they bring to postgraduate
study. Within the james Platt
White Society, fellows are
honored for gifts made during
any one year that total $2,500 to
$4,999.

Williamsville , NY

Dr. and Mrs. Pasquale A. Greco

Buffalo,

I Fellows '

I

Dr. William S. Andaloro

Caledonia, NY
Dr. George Bancroft

Hamburg, NY
Drs. Kevin and Elizabeth P.
Barlog

Dr. Willard H. and Mrs. Clarice
Bernhoft

Amherst, NY

Snyder, NY

Dr. jared C. and Mrs. Barbara A.
Barlow

Dr. Harold]. and Mrs. Arlyne Levy

Grand Island, NY

Amherst, NY

Dr. Robert M. Barone

Dr. Edward Shanbrom

Santa Ana, CA
Buffalo, NY

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La]olla, CA
Dr. Paul D. Barry

Dr. and Mrs. james]. White Jr.

m

Williamsville, NY

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Dr. Ronald E. and Mrs. Kathleen
Batt

Lancaster, NY

Dr. Mark and Mrs. Kathleen
Comaratta
East Amhnsl, ry

Gerard T. Guerinot, M.D. , and
Mrs. Geri Guerinot

Dr. Edwin j. and Mrs. Phyllis E.
Manning

Rochester,

Snyder, NY

Y

Dr. Ralph T . Behling

Dr. Lyn Corder

Dr. Eugene J. Hanavan Jr.

Dr. Michelle j. Marinello

San Mateo, CA

Buffalo,, Y

Blljfalo, 'Y

Williamsville,

Y

Dr. Richard A. Berkson

Dr. and Mrs. Daniel E. Curtin

Mrs. Gilda L. Hansen

Dr. William L. Marsh

Rancho Palos Verdes, CA

Orchmd Park, NY

Williamsville, NY

Bethesda, MD

Dr. Theodore . Bistany

Mrs. Joan D'A rrigo,
in memory of
Dr. Pete r . D'A rrigo

Dr. Reid R. and Mrs. Elenora M.
Heffner

Dr. Don L. Maunz

Buffalo, NY
Dr. john

. Bivona Jr.

Newbu rgh, NY
Dr. Willard H. Boardman

Buffalo,

Buffalo,, Y

Bangor, ME

Y

Dr. Merrill L. Miller

Dr. William j. Hewett

Richard H. Daffncr, M.D., and
Mrs. Alva K. Daffne r

Hamilton, NY

West Hartford, CT

Mrs. Edwina Mincks
in memory of
Dr. Charles B. Mincks Jr.

Robert M.jaeger, M.D.

Winter Park, FL

Ptllsbwgh, PA

Dr. Dennis L. Bordan

Port Washmgton, NY

Dr. David R. and Mrs. Sherrye
Dantzkcr

Dr. Suzanne F. Bradley

Roslyn, NY

Whitmore Lake, ,\1/

Dr. RogerS . and Mrs. Roberta
Dayer

Dr. Charles A. joy

Dean Mitchell , M.D.

Bt;Jfalo, NY

fairview, PA

Cortla nd, Y

Gerard]. Diesfeld , M.D.

Dr. Stephen T. Joyce

Dr. joseph F. Monte

Arcade, NY

Buffalo, \JY

Buffalo,

Dr. Thomas A. Donohue

Dr. and Mrs. James R. KanskiJr.

Dr. james]. Moran

Lexington, KY

Eggertsville,

Santa Monica, CA

Dr. Ronald l. Dozo retz

Drs. Julian R. and Mayenne A.
Karelitz

Dr. Thomas W. Bradley

Tonawanda, NY
Dr. Martin Brecher

Amherst,

Y

Dr. Harold and Mrs. Anne Brody

Amherst,

Y

Dr. James B. Bronk

Napa,CA
Dr. Melvin M. and Mrs. Elaine S.
Broth man

Snyder, NY
Dr. August A. Bruno

Amherst, NY
Dr. William M. Burleigh

Rancho Mtrage, CA
Dr. Washington Burns Ill

Berkeley, CA
Drs. Evan and Virginia Calkins
Hamburg, l\Y
icholas J. Capuana
New Hartford, Y
Dr.

Dr. Nicholas C. Carosella

Appleton, Y
Dr. Yung C. C han

Drapc1, VA
Dr. Michael E. Cohen

Williammlle, NY
Dr. D. Jackson Coleman

Ha worth, Nj

Allenl01vn, PA

Dr. Maynard H. MiresJr.

Moun/am Lakes, Nj

Norfolk, VA

Georgetown, DE

Y

Dr. Thomas W . Morgan

Dr. Robert B. Kaufman

North Brunswick, Nj

Ontano,

Potomac, \tiD
Dr. and Mrs. Kenneth K. Kim

Roanoke, VA

Clinton,

Dr. jack C. Fisher

Dr. Arthur C. Klein

Lajolla, CA

Los Angeles, CA

Dr. Penny A. Gardner

Dr. Robert A. Klocke

Los Altos, CA

Williamsville, NY

Dr. Kenneth L. Gayles

Dr. Paul S. Kruger

Manhasset , , Y

Y

Dr. Arthur W Mruczek Sr.

Medina, NY
Dr. Richard L. Munk

Sylvania, OH
Dennis A.

Dr. Lawrence H. Golden

Dr. Paul A. C. Greenberg

Y

Dr. Kim Griswold

Lockport, NY

Ri chard]. agel, M.D. and Mrs.
Florence agel

Dr. Gordon R. Lang

Orchard Park,

Poestenkill,

Dr. Masao
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Y

Eric, PA

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akandakari

Drs. Robert G. and Lillian V.

jamestown,

Carlisle, PA

Dr. Robe rt T. Guelcher

Y

Honolulu, HI

Dr. Stanley B. Lewin

Fort Myns, FL

adler, M.D.*

Velvedccr- Tiburo, CA

Dr. Andre D. Lascari

Dr. Edward F. Gudgel

a

PaulL.

Drs. joseph L. and Marie L.
Kunz

Chicago, IL

Btiffalo, \'Y

adler, M.D.

East Amherst, NY

Watertown, NY

Eggertsville, NY

Y

Dr. John D. Mountain

Dr. John A. and Mrs. Karen
Feldcnzer

Buffalo, NY

Y

Dr. Philip D. Morey
Williams1·illc, Y

Los Angeles, CA

Dr. Robert Einhorn

New York,

Mukilteo, WA

Dr. Kenneth L. and Mrs. Jane
Jewel

ey

Y

Dr. jack and Inez Lippes

Dr. Thomas P. and Mrs. Sandy
O'Connor

Buffalo, Y

East Amherst, Y

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Mrs. Marguerite T. O'Gorman

Dr. Joseph I. Schultz

Dr. Bradley Truax

Dr. Myron E. Williamsjr.

Eden, NY

San Pedro, CA

Lewiston, Y

Batavia, XY

Dr. Rudolph Oehm

Fred and Peggy Schwarz

Dr. Alvin Volkman

Dr. Richard G. Williams

Walnut Creek, CA

Williamsville, NY

Greenville, NC

Clearfield, PA

Drs. Dean E. and Donna W.
Orman

Roy E. Seibel, M.D. and Mrs.
Ruth H. Seibel

Dr. Arnold Wax

Dr. Lester E. Wolcott

Henderson , V

Lt1bbock, TX

East Amherst, NY

Eggertsville, NY

Dr. JohnS. and Mrs. Dorris
Parker

Dr. Molly R. Seidenberg

Dr. Harold J. Weinstein

Gregory E. Young, M.D.

Van Nuys, CA

Holland, NY

Dr. Arthur M. Seigel

Drs. Charlotte C. and Hyman
Weiss

Ca nandaigua, NY

Guilford, CT

Highland Park,

Dr. Elizabeth G. Serrage

Dr. Paul H. Wierzbieniec

Dr. Franklin and Mrs. Piera
Zeplowitz

Portland, ME

Amherst, NY

Buffalo, NY

Dr. John B. Sheffer

Dr. Gary J. Wilcox

Williamsville,

Carlsbad, CA

Dr. David C. and Mrs. Susan D.
Ziegler

Rochester, NY

Latrobe, PA
Dr. Robert J. Patterson

Snyder, NY
Dr. Norman L. Paul

Lexington, MA
Dr. joel H. Paull

Buffalo, NY
Dr. Victor L. Pellicano

Niagara Falls, NY

Y

Dr. Timothy S. Sievenpiper

Dr. Charles E. Wiles

East Aurora, NY

Ha111es City, FL

Dr. A. john Piccoli

Drs. RobertJ. Smolinski and
Claudia Fosket

Fort Myers , FL

Orchard Park, NY

Dr. and Mrs. Herbert S. Pirson

Dr. William L. Sperling

Orchard Park, NY

San Diego, CA

Dr. Cary A. Presant

Dr. John E. Spoor

San Marino, CA

Laurens, NY

Dr. Bert W. Rappole

JohnJ. Squadrito, M.D.

jamestown, NY

Troy, NY

Dr. Frederic D. Regan

Dr. William C. Sternfeld

Staten Island, Y

Sylvania, OH

F. T. Riforgiato, M.D., and Mrs.
Mary-Cecina W. Riforgiato

Middleport, NY

8

Dr. David W. Butsch

Montpelier, VT

Eugene M. Sullivan Jr. , M.D.

Dr. Richard R. Romanowski

Ms. Janet F. Butsch
Aurora, CO

Boston, NY

Williamsville, NY

Dr. Michael A. Sullivan

Dr. Charles H. Rosenberg

Buffalo, NY

Mr. Barry Swartz

Dr. and Mrs. JeffreyS. Ross

Dr. and Mrs. Marvin Z. Kurian

Amherst, NY

Albany, NY

Willtamsville, NY

Wayne C. Templer, M.D.

Dr. Albert G. Rowe

Harry L. Metcalf, M.D. , and
KaarenJ. Metcalf, Ph.D.

Corning, NY

Tonawanda , NY
Dr. David M. Rowland

Dr. and Mrs. James C. Tibbetts
Jr.

East Aurora, Y

Madison, WI

Dr. Eric J. Russell

Dr. Charles S. Tirone

Chicago, IL

Williamsville, NY

Dr. Adolphe J. and Mrs.
L. SchoepiTin
Green Valley , AZ

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Williamsville,

Y

Dr. john Naughton

Buffalo,

Y

Mrs. Marvin (Helen) Winer

Sarasota, FL

Dr. George Toufexis

ancy

Williamsville, NY

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In Memoriam

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The following individuals left
generous bequests or made
arrangements for gifts from
testamentary trusts to be given
to the School of Medicine and
Biomedical Sciences during the
past year.
Dr. Russell F. Brace

Randolph,

Y

Dr. Richard J. Kenline

Tonawanda, NY
Dr. Thomas A. Rodenberg

Hollywood, FL
Dr. Mark W. Welch

Rochester, :-JY

Dr. John L. Butsch

Williamsville, NY

Stamford, CT

ecial Members

A few individuals and couples
were granted multiyear
memberships based on generous
gifts made between 1989 and
1993. They will receive special
recognition through December
1999. At that time all memberships in the society will be made
on an annual basis, including
ongoing recognition for
Founders' Circle members as
they reach 550,000 in cumulative gifts.

Elizabeth A. Storch

Buffalo, NY

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Wa lnut Creek, CA

Las Vegas, NV

Hamburg, NY

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Dr. Wende W. Young

Dr. Roger M. Simon

Dr. Harry Petzing

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We have made every effort to
ensure accuracy in these lists.
Please contact Dr. Linda) .
Corder, Ms. Catherine Williams,
or Mrs. janet Parker in the
Medical School Development
Office if we have made an error
or if you would like your name(s)
to be listed differently in fut ure
recognition documents.
Send mail to: Room 141
Biomedical Education Building,
UB School of Medicine and
Biomedical Sciences, 3435 Main
Street, Buffalo, NY 14214-3013.
Phone: (716) 829-2773. Fax:
( 716) 829-3395. E-mail:
&lt;ljcorder@acsu.buffalo.ed u&gt;.

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Clinical curriculum traces
its roots to Buffalo
BY

S COTT

T HOM A S

t was half a lifetime ago, at the beginning of their careers .
But for five pioneering medica l educators who came
together once again to reminisce, the memories remain as
sharp as a new scalpel.
A "Celebration of Medical Education"
honored the five former UB faculty members
who created the Project in Medical Education,
an innovative effort from 1955 to 1959 to
expose beginning medical students to clinical experience and small-group teaching.
The project was revolutionary for its time,
and not without controversy. Previously,
medical students had spent almost all of their
first two years in the lecture hall. The Project

"we should bring together medical educators
and professional educators to see if there was
something we could learn from them-and
perhaps even they could learn from us."
The idea evolved, Miller said, into a series
of courses taught jointly by professors in
medicine and education, and programs for
visiting professors to spend time in both the
School of Education and the medical school.
'The colonization began there, but in the
course of the next few decades
it has spread worldwide," he
said. "All these schools have to
acknowledge that the seeds of
this movement began at the
[then] University of Buffalo."
Stephen Abrahamson,
Ph.D., Ed.D., was on the School

of Education faculty at the time;
his career has since taken him to
the University of Southern CaliLeft to right: Miller, Abrahamson, Rosinski, Jason, and Becker
fornia, where he is now professor emeritus.
He said he had one proviso when agreeing
in Medical Education got them into hospitals
and working with patients, an approach that to co-direct the Project in Medical Education:
has become the standard for medical educa- " o gross anatomy, and no operating room. "
Abrahamson noted the rise of "a bottomtion in the United States.
At an April 24 presentation, the five pio- line mentality" with the advent of managed
neers shared thoughts on why the project care; he also pointed with hope to the enorsucceeded so thoroughly, and where medical mous amounts of material now widely
education might be going in the years ahead. available through the Internet.
"In my 35 years of medical education,"
George E. Miller, M .D., co-director of
the project, went on to the University of he added, "''ve tried to learn not a damn
Illinois Medical School and is now professor thing about medicine. And the little I have
learned has made me pray for health. "
emeritus there.
Edwin F. Rosinski, Ed.D., earned his docHe spoke of how Stockton Kimball, dean
ofUB's medical school at the time, agreed that torate at UB while working on the project.

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Since then, his career has taken him to the
Medical College of Virginia; the U.S. Department of Health, Education, and Welfare; the
University of Connecticut; and the University of California at San Francisco, where he
is now professor emeritus.
Rosinski predicted a greater emphasis on
outpatient and primary care-the latter a
strength ofUB's medical school curriculum,
which has become a national model.
Hilliard Jason, M .D., Ed.D., earned his
medical degree and his doctorate in education from UB. He now directs the Center for
Instructional Support, in Boulder, CO, and
is clinical professor of family medicine at
the University of Colorado Medical School.
jason recalled an initial disillusionment
with medicine, due to a histology professor
who "insisted that we spend hours peering
through a microscope at tissues and putting dots on paper to match the shading of
what we saw. "
That changed with the Project in Medical Education. "I was so excited that there
was somebody here who was challenging
the status quo. There was this other side of
the school that was enormously exciting
and enriching."
jason sees a plus side to managed care.
"The arrival of the bottom-line mentality
brings with it the notion of accountability.
We have not had that in medical education. "
Donald Raymond Becker, M.D., taught
surgery at UB until1980, then went to the
University of Connecticut at Hartford. ow
emeritus there, he teaches at the University
of California at Davis.
"There have been so many changes in
medicine in the past 40 years," he said.
"Humanism courses and biomedical ethics
committees; AIDS; more women and minorities in the profession. Some say medicine has
become too cold, too remote, too impersonal,
too unavailable, too money-hungry.
"But when students today ask me if I
would do it all over again, my answer is
still: 'In a flash! ' Why should it matter to
me who pays me or how much paperwork
I have to do? There will always be the sick
who need healing. "

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percent overfive years

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he number of medical residents
trained in Buffalo will be reduced
by about 20 percent over the next
five years in response to a Medicaid incentive program and cuts at
the Veterans Administration.
The Graduate Medical Dental Education Consortium of Buffalo had 687
Medicaid-funded residents in training
in 1996. That number will be reduced to
about 545 by the year 2001 , said
Roseanne Berger, M.D., UB associate
dean for graduate medical education.
The cuts are part of an incentive program for ew York State hospitals
offered by the federal Health Care
Financing Administration, which runs
Medicaid. During the five years of the
cuts, HCFA will ease the transition by
paying the participating hospitals a percentage of the money they would have
received had they continued to train
residents at 1996 levels.
At the same time, the Veterans Administration is also cutting back on residency training. The Buffalo consortium
now trains about 101 VA-funded residents; over five years, this figure will be
cut to about 89, according to Gerald
Logue, M.D., chief of staff at the Veterans Affairs Western
ew York
Healthcare System at Buffalo.
The result will be a reduction in the
number of Buffalo-area medical residents from 788 to 634. Also, a larger
percentage of the remaining residencies
will be in primary care areas.
"Residencies are paid for with public
money, so the numbers and types of
residents should be driven by what the
country needs," Logue said.
Nationally, there is a concern that
schools are training too many doctors,
and specifically, too many specialists.
There's also concern about the high cost
of medical education, which contrib-

Physician

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utes to the overall expense of health
care. For example, federal budget officials have predicted that the Medicare
Trust Fund, which is the source of much
of the country's GME funding, will have
a $600 billion deficit by 2002.
As long as residency training provided income for hospitals, there was a
strong incentive to create more residency positions and use the residents to
take care of indigent patients. Sometimes, residents found themselves performing procedures not because they
were required for board certification
but because the hospital had no one else
to do them. The
trend has resulted in
many more residency
positions than can be
filled by graduates of
American medical
schools, leading hospitals to recruit international medical
graduates (IMGs).
The changes are
likely to start reducing the number of
IMGs in the U.S., and Roseanne Berger
residents may soon be able to select the
types of hospital work they need in
order to meet their own educational
priorities rather than doing what is
needed to care for patients.
In addition to the changes in the two
federal sources of GME funding, more
changes are afoot at the state level due to
the ew York State Health-Care Reform
Act of 1996. Details remain to be worked
out. However, Berger said these changes
probably won't result in deeper cuts in
Buffalo's programs.
The changes provoke a variety of
reactions at UB. Some feel that residents will end up better off: "I think
this has the potential to strengthen
many of our residency programs, "
Berger said. "Many of our faculty see it
as an opportunity." +
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JESSICA

ANCKER

�_,

............ . . . .................................. . ..................................... .

lEI

Asthma in the urban community

BY

MICHAEL
CLASS

KANE ,
OF

1998

NOW I KNOW IT'S NOT THAT SIMPLE

lenty of studies show that asthma is a growing concern of the inner city. The challenge that I am
seeing early in my medical career is making the transition from textbooks, algorithms, and studies
to actually helping people with asthma manage their condition outside the physician's office.
Over the past two years, I have had the chance to see up close the environIn addition, I learned the importance
the opportunity to work with Carlos ments in which Lower West Side asth- of being sensitive to the financial rejaen, M.D., and the Center for Urban matics live.
sources of patients. Physicians often tell
Research and Primary Care (CURE PC)
Of the asthmatics we studied, 80 per- asthmatics to vacuum frequently to reon a comprehensive asthma study done cent were Hispanic, two-thirds received duce the level of dust, or to get rid of
in Buffalo's Lower West Side. We iden- public assistance, and more than half cockroaches. But some patients can't
tified asthmatics in the community and were exposed directly or indirectly to afford a vacuum cleaner, and they may
gathered information about their medi- environmental tobacco smoke. Fewer have no choice but to live in cockroachcal management and knowledge of than half of the adults had a high school infested subsidized housing.
asthma, their home environment, their education.
More effort has to be put into smokexposure to environmental tobacco
My eyes have been opened to many of ing prevention/cessation programs.
smoke, and their socioeconomic status. the problems physicians face
I joined the research team in per- when treating a chronic disease
forming more than 800 home inter- in an urban community. One
views in this poor, urban community. I of the most obvious problems
became aware of the many sociopolitical was communication. I speak
problems of this area, and of many asth- very little Spanish. Sitting in
matics' poor understanding and man- patient interviews with a biagement of their condition.
lingual researcher, I imagined
The a tiona! Asthma Education Pro- what it must be like for a
gram publishes guidelines for managing
panish-speaking patient who
asthma, ranging from the use of corti- enters an emergency room and
costeroids, bronchodilators, and peak gets maybe 30 seconds of inflow meters, to the elimination of envi- struction for preventing the
ronmental irritants, such as dust, pets, next acute asthma attack- in
or tobacco smoke.
English.
When l first read those guidelines,
I gained a better appreciathe management of asthma seemed easy tion of explaining things in
enough. I thought that there was noth- plain language. Before I studied
ing about asthma that couldn't be ex- asthma, I had no idea what a
plained and brought under control after " nocturnal exacerbation "
a few 15-minute visits to the clinic.
was- it just
sounded
ow I know it's not that simple. Dr. serious. But that's the kind of term a Almost all the people we interviewed
jaen tells his medical students, "In order doctor is Iikely to use when describing a knew that tobacco smoke can make
to practice good medicine, you must night-time asthma attack. It's no won- asthma worse , but many still lived in a
know the community in which you prac- der some patients-whether they speak smoke-filled environment. One home
tice." My experience with him gave me English or not- don't understand.
we visited had four children under the

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�UBMICRO

COMPUTER SALES
A Non-Profit
University at Buffalo Se ice Program
age of seven with asthma. one of the
children were on any sort of treatment
plan, and each of the parents smoked
two packs of cigarettes a day. I asked
what they did when their children had
trouble breathing. The parents replied ,
"Take them to the emergency roomwhat else? "
Besides the asthmatics who had no
medications to take , there were others
who took potentially harmful medications incorrectly. In one home , I interviewed a girl and her grandmother,
both with asthma. During the interview , the girl began wheezing. She took
an albuterol nebulizer treatment, and
when that brought only partial relief,
she went to her grandmother's medicine tray and took one of her
grandmother's prescription 300 mg
theophylline tablets.
When I asked about it , the granddaughter explained that she some-

Letter to the Editor

times had to take her grandmother's
medication because it was stronger. I
took the opportunity to tell her that
these medications-and others-can
be dangerous iftaken inappropriately.
I urged her to talk to their physician
about a medicine review. But even
though we both were speaking English , I suddenly got the feeling that I
was speaking a foreign language.
It is very easy to feel that these sorts
of problems are out of the physician's
hands, and that people will do whatever they want. However , after working on the CURE PC project, I know
that I am going to try my best to confront many of these problems and work
with patients for a better quality of life.
That, after all , is what the patients
really want. +
Mi chael Kan e, who wi ll sLa rl hisfatmh yem of medi cal
school this f all, is C0 11 sideri11g el!l cringfamil) medi cin e.

Buffalo Phys ician received this letter in respo nse to Mike Merrill's

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1 thought you 'd be interested that a guy as far away as Oklahoma really

enjoyed your article "Medicine is a Game of Power" in Buffalo Physician.
Thirty years ago, I took a watered-down version of the Oath of Hippocrates,
which I suppose you will soon do. But keep in mind the spirit of the original .
And the violations of it.
In my opinion, in spite of "powerful enemies, " the intrinsic value of a good
physician is tremendous and will prevail. Water finds its level.
Third-party pay is inherently corrupt. You will be more valuable than you think.

r

Cordially,
Summer hours: Mon thru Fri I 1-S

Ed Ellis , M . D .
Rowland Ellis Flatt Clinic
Antlers, Oklahoma

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New Alumni Association ollicers elected
ared C. Barlow, M.D. , was elected
president of the Medical Alumni
Association at Spring Clinical Day
on April 26.
Barlow, an anesthesiologist, is
medical director and
administrator of the
Millard Fillmore Surgery
Center in Williamsville,
Y, and serves as chair of
anesthesiology for the
Millard Fillmore Health
System. A UB clinical associate professor of anes- Jared C. Barlow

thesiology, he graduated from the medical school in 1966. Barlow was recently
appointed to a three-year term on the
New York State Committee on Quality
Measurement, which develops quality
measures and promotes research on
clinical practice guidelines.
He succeeds Jack F. Coyne, M.D ., as
president of the Medical Alumni
Association.
Elizabeth L. Maher, M.D., becomes
vice president of the Medical Alumni
Association. Maher is a 1985 graduate
of the medical school and a UB clinical

instructor of medicine.
A specialist in family
medicine , she is an
emergency department
Elizabeth L. Moher
attending physician at
Medina Memorial Hospital.
Richard Collins, M.D. ,
a primary care physician
with the Buffalo Medical
Group, is the new treasurer
of the Medical Alumni
Association. He also served
as program director for
Ri(hord Collins
Spring Clinical Day. +

Alumni Association honors four
our prominent alumni were honored with Lifetime Achievement
Awards from the Medical Alumni
Association at Spring Clinical Day.
Pictured below, from left to
right, they are Jack Lippes '4 7,
Eugene Marvin Sigman '52, Ross
Markello '57, and Richard Ament '42.
Of Lippes' research into reproduc-

Left to right: Lippes, Sigmon, Morkello, and Ament

tion and contraception, his best known
work is the invention of the S-shaped
intrauterine device known as the Lippes
Loop. His biochemical studies of oviductal fluids have also been instrumental in
developing treatments for infertility. A
UB professor of gynecology and obstet-

®

rics , Lippes has served as an international family-planning consultant to the
World Health Organization, as well as
numerous countries. He serves on the
IUD committee of the International
Planned Parenthood Federation.
Sigman held positions in the Departments of Urology and Surgery at UB,
Buffalo General Hospital, and Roswell Park
Cancer Institute
before moving to
the University of
Connecticut as
professor of surgery and chair of
urology. In 1985 ,
he became dean
of the University
of Connecticut
School of Medicine, a position from which he recently
retired.
Markello , a former chair of anesthesiology at UB and E. J. Meyer Hospital
(now Erie County Medical Center),
recently retired as associate medical
director of Independent Health of

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Western ew York. He served UB as
assistant dean for graduate medical education from 1978 to 1981. Markello has
held a Sloan Fellowship through the
Massachusetts Institute of Technology
School of Management's Health Executive Development Program. Among
numerous other professional honors
and activities , Markello served from
1980 to 1981 as associate project director of the Love Canal Cooperative
Health Study for the Centers for Disease Control and Prevention .
Ament , a clinical professor of anesthesiology at UB , is a past president of
both the American College of Anesthesiologists and the ew York State Society of Anesthesiologists. He also served
on the executive committee of the
World Federation of Societies of Anesthesiologists and as secretary of the
Council of Medical Specialty Societies.
An active member of the American
Medical Association , he has testified
on medical issues before Congress and
the U.S. Justice Department. +
-J.A.

Physician

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�Reunions at 60th annual Alumni Weekend

1 9 4 7
First row (left to right): Ferdinand Paohm, Hallie Buchanan Mont,
Peter Juhan, Robert Ehrenreich Second row (left to right): james
Philhps, james Stagg, Arthur Schaefer, Daniel Curtin, Phihp ReitZ,
Donald Nuwer, Ste\'en Cline, William Baker, Harold Pescovitz, David
ichols, Elbert Hubbard Ill Third row (left to right): Robert jaeger,
Robert Segal, Robert Dean, john Sheffer, Hans Kipping, Frederick
Whiting, john Waite, john Weiksnar

First row (left to right): Oli\·er Steiner, Burton tulberg, Bern1e Dm•1s,
Phoebe aturen, Kurt Wegner, james Szabo Second row (left to right):
eil Fuhr, Eugene Sigman, Donald Dohn, Victor Panaro, Ralph Obler,
joseph Gene\~ich, Melvin Oyster, Alfred Lazarus, Wilbur Schwanz, S.
Aaron Simpson, Robert Baumler, Donald Sprecker

1 9 5 7
First row: Roberta Gilbert Second row (left to right): George R.
Tzetzo, David Carlson, Anthony Markello, joseph Armenia, Arnold
Lubin Third row (left to right): jack Fisher, Sebastian Fasanello, Paul
Loree, Owen Bossman, Robert Klocke, john Cudmore, Philip Morey

First row (left to right): Charles O'Connor, Gregory Thorsell, Ben
Celniker, Bronson Berghorn, Ross Markello, Richard Miller, Hilliard
jason Second row (left to right): Bernard Wakefield, james Lasry,
Robert Carpenter, Germante Boncaldo, john Parker

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1 9 6 7
First row (left to right): Thomas Augustine, Laird Quenzler, John
Treanor Second row (left to right): Margaret Brown, Thomas
Sheehan, John Menchini, Douglas Sirkin, Adele Gottschalk, Linda
Young, Richard Young, John Anderson, Ronald Josephson, Barry
Epstein Third row (left to right): Frank Perlroth, Rocco Venuto,
Michael Phillips, William Burleigh, Trevor Robinson, Jonathan Ehrlich,
Harvey Schwartz, Alan Saltzman, Arthur Sosis, Donald Miller, Thomas
O'Connor, James Giambrone, David Fugazzotto, Anthony LoGalbo

First row (left to right): Dennis Gross, Virginia Hawley, Robert
Einhorn, Linda Kam, Joseph Oliver Second row (left to right): Alan
Ast, Stuart Rubin, Robert Folman, Ian Frankfort, Martin Brecher,
Murray Morphy, Richard Rivers, Russell Elwell

First row (left to right): Eugene Paul, Thelma Caison-Sorey, lldiko
Kondray, Antoinette Wozniak Second row (left to right): Alan
Kuritzky, Howard Lippes, Albert Schlisserman, Steven Stone, Helen
Marie Findlay, Kevin Greenidge, Nedra Harrison, Gregory Young, Janice
Williams, John Norlund, Richard Terry, Michael Kressner

First row (left to right): Gerald Harster, Michael Cesar, Joseph Leberer
Second row (left to right): Timothy Gee ring, Joseph Gelormini, Mary

®

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Kelly, Elizabeth Barlog, Kevin Barlog, David Kurss, Michael Bartlett
Third row (left to right): Joseph Gioia, R. Scott Crandall, Philip

Stegeman, Benjamin Contessa, Joseph Wayne

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�First row (left to right): Beth Wutz, Elizabeth Conroy, Katharyne
Sullivan, jack Hsrao, Patricia Reddin Vories, Marie Longo, E\·elyn
Coggins, Stephanie Fretz Second row (left to right): Randall Loftus,
Mark Swetz, Cynthia jensen, George Pancio, Mrchael Longo, Paul
Paterson, Atle Skattebol

(Identification not ava ilable befo re publication)

If you come loolting for a car,
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HoWEVER, there's little chance you'llleave that way. BECAUSE at the Land
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.

THE ULTIMATEDRIVING MACHINE:

•
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ogy and was named McAllen's

of

"1996 Honoree. " Kuhl moved

Y, writes, "From the

to south Texas after complet-

forgotten '30s: Last time 1

ing his residency in dermatol-

HENRY

H .

Snyder,

HAIN ES ' 33 ,

checked, there were ten M.D.s

ogy and serving in the U ..

from 1933. 1 sent a letter to all
and was immediately informed

Army and the Public Health
Service. In addition to his prac-

there were nine still alive. Some

tice, Kuhl helped found a clinic

are still healthy, one with a

for Hansen 's disease and

Checkpoint Foreign Car, Inc.
Sales and Service
487 Kenmore Avenue
Buffalo, NY 14223

stroke, me with two bypas es

worked in the county venereal

and cataracts, but still ambula-

disease clinic. A past president

tory. I'm still registered, for

of the Texas Dermatological
Society and a member of the

836-2033

etc.), but retired. 1 turned 90

City Health Authority, he

year old on May 4."

served as clinical associate pro-

Your WNY Leasing Specialist
Serving WNY proudly for 33 years

convenience (prescriptions,

fessor at the University of Texas

1

9

IV A N

W.

4

0

K UHL ' 45 ,

5
of

McAllen , TX, recently retired
from his practice of dermatol-

Science Center for 17 years.
With his wife, Ruth , he raised
nine children, two of whom
have become physicians.

TAKE TWO~ -..
AND CALL ME IN THE
MORNING!
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OW'\

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Physician

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�······································· · ··················································•

HI
'

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5

JAMES E . YOUKER '5 4 ,

of

FRANKLIN ZEPLOWITZ '58 ,

in May. His new bride,

of Buffalo,

Margarita (whom he met in

medicine.Iwillbeteachingstudents and residents in the
ambulatory setting.

Y, is the new

Hartland, WI, received the

president of the

Bogota on Project World

Gold Medal of the Association

Medical Society

Health), graduated in 1996.

of University Radiologists at its

of the County of

They matched in Seattle for

45th annual meeting in Dallas,

Erie. He suc-

neurosurgery and family practice, respectively. David Sherer

system chair of pediatrics for
Atlantic Health System in

annually to an outstanding

ceeds Russell
Bessette '76.

'69 has been hospitality king

radiologist for long-term

Zeplowitz

during the interviews."

contributions to education,

the

TX. The honor is awarded

is

1

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cago, IL, has been elected vice

and is chair of the radiology

as a clinical instructor of sur-

president of the American Soci-

ERIC RUSSELL '74 ,

gery at UB.

Lackawanna,
classmate
Rasinski

julius

Jr. '59, of Durango,

CO, retired early in 1996 as a
family practitioner. He had

he will be re-

of Chi-

Sandra Fernbach, M.D., was el-

Victor

system chair,
sponsible for
merging all pediatric care un-

ety of euroradiology. His wife,

College of Wisconsin.

9

of

], has been named

5

director and chief of staff at

1

FELD '79 ,

J. As the first

Our Lady of Victory Hospital
in Lackawanna, NY, and serves

of
Y, writes: "Our

Randolph,

medical

research, and patient care.

DANIEL C . KOZERA '59 ,

LEONARD G .

Florham Park,

Youker practices at Froedtert
Memorial Lutheran Hospital
department at the Medical

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evated to the executive council
of the American Roentgen Ray

WILLIAM E . ABRAMSON '60 ,

of Baltimore, MD, recently

Society.
KAREN

tification in addiction medicine
from the American Society of
Addiction Medicine.

der one department for the hospitals and the
outpatient facilities. Atlantic
Health System serves as a major
teaching affiliate for both

passed the examination forcer-

been the team physician for

GLASGOW '76 ,

of

ew

jersey Medical School and Co-

Columbus, OH, writes, '·Re-

lumbia University. Feld has been

cently, I left a multidisciplinary

chief of pediatric nephrology,
director of the Children's Kid-

group practice to become the

the California Angels ever

MOIRA J .

of

assistant program director of

ney Center, and professor and

since the team was founded.

Tampa, FL, writes: "Two new

internal medicine at Riverside

vice chair of pediatrics at UB and

He also served as team physi-

physicians have been added to

Methodist Hospital in Colum-

the Children's Hospital of Buf-

bus, where my husband, Pat
Hayes '76, practices emergency

falo since 1983.

cian for the L.A. Rams."

BURK E

'69 ,

my family. My son, Brendan,
graduates from medical school

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.

HURWITZ &amp; FINE, P.C.

I

[

1
EDWARD

9
A.

8
TORIELLO

0

ATTOR

EYS

AT

LAW

I

I N F I N IT I

5

S ERVICING

'80, of Brooklyn,

THE L EGAL

NY, was appointed to the board of directors
of the American Academy of Orthopaedic
Surgeons at the organization's 64th annual

N EEDS OF THE

meeting in February in San Francisco. He is

H EALTH S cm cEs

chieJ of the Department of Orthopaedic Surgery at Wyckoff Heights Medical Center in
Brooklyn, and is attending orthopaedic surgeon at St.john's Queens Hospital , Catholic

C OMMU ITY

Medical Center, in Queens. Toriello also
serves on the board of directors of the New
York State Orthopaedic Society and as a

• Purchase &amp; Sale of Practices

The f ront-wheel Jrive lnj initi® 130n 1

• Managed Care

• Business &amp; Tax Planning

delegate for the Medical Society of the State
of ew York.

An titterior more .•paciotM than a Roll• Royce
Sil&lt;•er Spur 11!. An e:rceptionally gmmllt.J li.&lt;t
of .&lt;fanJard lu.-rury feature,&lt;. A 190-hp V6
mpable 4 out-acceleratin,q many lu.mry v&amp;•.
AnJ of cour.&lt;e, the ,&lt;/andard-,&lt;elling
performance and ,&lt;erl'ict of lnfiniti.

• HCFA Safe Harbor Regulations
SJ99 mo. 56 mo. lean $999.00 dOII'n

and Physician Self-Referrals
LYNDA KARIG HOHMANN

'81 , of Albany,

Y, writes that she joined the Capital Dis-

• Contracts with Private

trict Physicians Health Plan as associate
medical director. Prior to that, she had been

&amp; Public Entities

medical director of a local addictions pro-

• Employee Relations

gram for four years. "Heather, my daughter,
turns 21th is year and plans to go to medical

Counseling

school in another year."
JANET

• Fringe Benefit Programs

'84 and JOHN
'84 , of Morgantown, WV,

WILL I AMS

BARBACCIA

• Representation Before
Government Agencies on

announce the birth of their fourth child,
Nicholas Andrew. He joins Katie (5), Matthew (3), and Thomas (1).john is residency

Audit &amp; Business Issues
• Facility Finance

director for the Department of Anesthesiology at West Virginia University; janet is
research director in the university's Department of Emergency Medicine.

and Construction
• Credentialing
and By-Laws

MARTHA PAVLAKIS

ln t r ouu cing tbe a ll n ew 97' QX4®
f r om SJ5,550. 00
in an lnfiniti® QX-1®, one of tbe fit-.&lt;1
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Becau.1e !be QX-1 i.1 not your typical
lu.-rury .&lt;portuttlity l'tbicle. lflbi/.e it 1!{/erd
all tbe l'tr.latility you e:rpect from a
l'ebicle of it.&lt; kint), tbe QX-1 offer.~
.Jome/ bin.9 you Jon 't e.~flecl: tbe lu.~·ury
of an lnfiniti.

'88 , of Stanford, CA,

• Hospital/Medica l Staff Issues

is an assistant professor of medicine (nephrology) at Stanford niversity Medical Center. "My clinical work is in kidney and
pancreas transplantation, and my research

Please contact
Robert P. Fine or
Lawrence M. Ross
at 716-849-8900

interests are acute rejection and gene expression in transplant dysfunction. "

I N F I N IT I

AUTO PLACE INFINITI
8129 MAIN ST. , WILLIAMSVILLE

633-9585

'88 and MARY DAVITT
Y, write, "We are proud to

M ITCHELL TUB LIN

'88 , of Albany,

East of Transit Rd.,
Near Eastern Hills Mall

announce the birth of our third son, Andrew
james Tublin , on October 15 , 1996. Andrew
joins Daniel (4) andjoshua (18 months) in

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Buffalo, New York

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Physician

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�.........................................................•

11
'

Advertise in one of the
finest publications in
Western New York ...

the Tublin gang! Mitch is assistant professor
of radiology at Albany Medical Center; Mary

state, and national levels." He had served for
four years as the student representative to

is practicing pediatrics, also at Albany Medical Center."

the medical society's advisory council, and
as student councillor to the ew York State
Medical Society's governing council. He is

CAROL

V.

R .

DECOS T A

' 89 ,

of Brooklyn, NY, writes, "I was recently
promoted to associate director of outpatient
rehabilitation at the Staten Island Univer-

Buffalo Physician

sity Hospital. My practice also includes sports
medicine. I was one of the physicians
who covered the volleyball players during
the Centennial Olympic Games in Atlanta
last summer. "

RUff"tU

f"~S\[\""

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5

MARY RITA MURPHY '90, ofMarshalltown,
lA, has moved from Tucson, AZ, to Iowa and
will be in private practice with a partner

starting in October. She writes that she is
happily married and has three sons, ages
5112, Jih, and 18 months.

(716) 645-6933
Michael J. Baranski
Marketing Representative

ADVERTISING

146 Stepping Stone Lane
Orchard Park, NY 1412 7

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hysic

Levey is starting a residency in obstetrics
and gynecology at George Washington University.

RESIDENTS
A . SWIANTEK ('73-'76), of

Williamsville,

Y, is in the process of pat-

enting an instrument for prostate surgery
called the ortech Sled. The instrument
allows surgeons to perform electro-surgical
vaporization for soft-tissue resection and
desiccation. He writes that the procedure
resects through soft tissue, prevents postoperative bleeding, and yields high-quality

of Vienna, VA,

tissue samples for pathological analysis.

writes: "I have been appointed to one of the
chief resident positions in the Georgetown

OBITUARIES

CRAIG

CHEI FETZ

' 95 ,

Internal Medicine Program. I have recently
won an award as a finalist at the Washington
Regional American College of Physicians
meeting for a poster presentation on
Rhodococcus equi pulmonary infections. I
have been elected to serve on the ACP Washington, DC, Regional Associates Council."
REGINA Y. K I M '97 . of Akron, OH, is
starting her family medicine residency program at Akron City Hospital!NEOUCOM . "I
got married on October 12, 1996, in Rochester, NY, to Edward B. Yoon , M.D. , who is
a fourth-year OB-GY resident at Akron
City Hospital. We have a new yellow Labrador pup named Scout."

BARANSKI

also an alternate delegate from the AMA
Medical Student Section to the American
Medical Association's House of Delegates.

PHILIP

1

Give us a call :

I

K E NN ETH L E V E Y '97 , ofBuffalo, Y, was
honored by the Medical Society of the County
of Erie at its annual meeting in May. He was
recognized for "being an enthusiastic representative of organized medicine at the local,

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ROBERT OEH L ER ' 38 ,

of Amherst, NY,

died May 23 , 1997, after a long illness. The
retired surgeon and veteran of World War II
was 82. Born in Buffalo, he attended School
53 and was a graduate of East High School.
After earning his medical degree, he completed his residency at Buffalo General Hospital. He entered the U.. Army in 1941 ,
serving until1946. His assignments during
the war included duty on the Aleutian islands off Alaska. Oehler returned to Buffalo
after the war to open his surgical practice
and was on staff at Buffalo General Hospital
and Children's Hospital until his retirement
in 1979. He was a member of the American
College of Surgeons, the American Medical
Association, the Buffalo Surgical Society,
and the Gross Medical Club. An avid fisherman and hunter, he was also a member of
the Buffalo Athletic Club. He is survived by
his wife of 4 7 years, the former jean Yeo.

�.
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[1]

Magnificent
BUILDING LOTS

.

I

of
Williamsville, Y, died March 23, 1997. A
pioneer in alcohol rehabilitation, he helped

the American Urologic Association. Among
his honors were election to fellowship in
both the American and the Royal Canadian

publicize the concept of alcoholi m as a
di ease and a public health problem. In

Colleges of urgery. He served as president
of the iagara County Medical Society and

1948, he started and directed the first alcohol rehabilitation center in ew York State.
He also worked with Alcoholics Anonymous in treating patients. Born in Buffalo,

the Buffalo Urological Society, and was an
enthusiastic teacher as an assistant profes-

KENNETH

GOLDSTEIN

' 39 ,

Goldstein was the 1932 Buffalo Evening ews
city tennis champion and state doubles champion. After earning his M.D. , he completed
a residency at the former E. j. Meyer Memorial Hospital , and served as a major in the
Army Medical Corps during World War II.
Goldstein practiced internal medicine and
gastroenterology in Buffalo, teaching at UB
as a clinical professor and serving on the
staffs of Millard Fillmore Hospital and E.].

to Tucson . He was hired by THMEP to serve
as chief of urology and director of the urology training program at the County and
Kino Community Hospitals from 1975 to
1983. After a brief retirement, Baer served
eight years as the first urologist of the Salt
Lake City FHP Medical Group before re-

Medical Alumni Association. He is survived

oughly enjoyed his full life with his family,

by his wife, Loraine, and a son, Harvey R.

his varied medical practice experiences, and
his love of golf, traveling, sailing, and skiing. He is survived by his wife of 50 years,
Babette; his three children, David (of Pied-

BAI SC H

'45 ,

of La

jolla, CA, died last year at the age of 74. A
surgeon, he was certified by the American
Board of Surgery and the American Board of
Thoracic Surgery.

The Summit at &amp;herff is a truly extraordinary
residential development, unrivaled in Western
New York. estled in the hills of Orchard
Park, this magnificent 81-acres has been
subdivided into 50 estate-sized building lots
surrounded by Chestnut Ridge Park and
Neuman Creek in a very private enclave.

turning again to Tucson to retire. ever
the type to consider retirement an all-ornothing event, Baer then served as a cruise
physician for Society Expeditions. He thor-

BRUCE F O RDIN G

As a former president of
the University at Buffalo
medical school Alumni
Association and a
practicing surgeon in
Western ew York
for many years, I've
come to understand what members of our
profession desire in a home site · privacy,
tranquility, fresh air, and pristine surroundings.

sor of surgery and urology at the University
at Buffalo. In 1975 Baer and his wife moved

Meyer. He was a past president of the UB

Goldstein, M.D., UB Class of'77.

Dear Colleague:

Specifically as an escape from the fast-paced
everyday life we lead, it's features include:
• Spectacular panoramic views of the Canadian
shores, Lake Erie, and the Buffalo skyline

mont, CA), Laurence (of Laurel, MD), and
janet Elisabeth (of Brookline, MA); and his

• Mature woods and secluded ravines

ten grandchildren; as well as by his brother,
Howard (of Plant City, FL).

• Quick and easy access to the freeway systems
leading to Buffalo and the city's northern suburbs

• Oversized lots for your dream house

• Privacy, seclusion, and exclusivity
R ICHARD A . BAE R '46 ,

of Saddlebrook,

AZ, died March 26, 1997. He was born in
iagara Falls, Y, on August 5, 1921. After
graduating from the University of Michigan
and the University at Buffalo medical school,
he served a year's internship at Sisters of
Charity Hospital in Buffalo before joining
the U.S. Navy. He spent two years on the
medical staff of the Great Lakes Training
Center Hospital and then completed further
training in surgery and urology
at Mt. Sinai Hospital , Metropolitan
Hospital, and Western Reserve University
in Cleveland, OH. Baer then returned to
iagara Falls, where he practiced urology
for 22 years. He was a diplomate of the
American Board ofUrology and a member of

®

of Orlando, FL, died injanuary of cancer. Born in

J O HN L AWR E N CE MU SSER ' 51 ,

The Summit promises to be one of the
premier areas in Western New York to
construct your ltLxury residence. 1 invite
you to take a stroll through this picturesque
setting. For our detailed brochure or a private
shmving please call (716) 667-2237 or

Buffalo, Musser served as a sergeant in the
.S. Army from 1941 to 1945 in the orth
African campaign of World War II before
going to medical school. In 1958, he and his
family moved to Hawaii , where he practiced

(716) 472-3790.

at the Hawaiian State Hospital in Paavilo
Sincerely yours,

and served as chief of psychiatry for Hilo
Hospital and Institution of Mental Health.
Musser also served in the Peace Corps. After
returning to Western ew York in 1965, he

Edmond J. Cicewicz, ~1.0.
Past President, UB Nl.edical Alumni Association

practiced psychiatry in Mayville, Y. He
moved to central Florida in 1986 and worked
for the Seminole County Public Health Department. He is survived by his wife, orma,

THE

SUMMIT AT SCHERFF

and three daughters.

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they are, physicians and other health care providers
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BUFFALO PHYSICIAN

U.S. Postage

STATE UNIVERSITY OF NEW YORK AT BUFFALO

PAID
Buffalo, NY

3435 MAIN STREET
BUFFALO NEW YORK 14214

Permit No. 311

ADDRESS CORRECTION REQUESTED

Planned Giving to UB.
Tax deductions and on ncome for l·fe ore only

port of the benefits you con receive with

planned g;v;ng to the UB School of Medic ne

and Biomed·col Sciences. You needn't be

wealthy, or a financial genius. All you need is

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For more information, contact Lyn

Corder Ph D., CFRE, at (716) 829-2773, or v1o
e-mail ot ljcorder@ocsu buffolo.edu.

UNIVERSITY AT BUFFALO
tate L"niwsity rf.\ ew l iJ1k

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State University of New York at Buffalo School of Medicine and Biomedical Sciences, Autumn 1997

�BUFFALO PHYSICIAN

\ olume 31, Number 4
ASSOCIATE VICE
PRESIDENT FOR
UNIVERSITY SERVICES

Dr Carole

~m1th

Petro

DIRECTOR OF
PUBLICATIONS

Kathryn .-\ Sa\mer
EDITOR

Judson \1ead (lntenm)
ART DIRECTOR/DESIGNER

AlanJ Kegler
PRODUCTION MANAGER
\nn Raszmann Brown
STATE UNIVERSITY OF
NEW YORK AT BUFFALO
SCHOOL OF MEDICINE
AND BIOMEDICAL
SCIENCES

Dr John \\'nght, /ntcmn Dean and
V1&lt;r P•cllllrntfor Climwl A{fw11
EDITORIAL BOARD
Dr Bertram Partin, Chail
Dr \t1artm Brecher

Dr llarold Brodv
Dr Lmda J . Corder
Dr Alan J . Drmnan
Dr james Kanski

Dr Barbara Majerom
Dr Elizabeth Olmsted
Dr Charles Paganelli
Dr Stephen ~pauldmg
Dr Bradley T Trua'
Roy Vongtama
Dr Frankhn Zeplow 1tz
TEACHING HOSPITALS AND
LIAISONS

The Buffalo General Hospnal
.\1iclwcl Sha"
The Chlidren·s llospnal of Buffalo
Eric County 'Vted1cal Center
Mercy Health System
Mlila~d Fillmore Health '&gt;ystem
Frcmll Sm·a
Niagara falls Memonal Med1cal
Center
Roswell Park Cancer lnsutute
~!Sters of Chanty llospnal
Dl'mm .\1cCw thy
Veterans Affairs Western New York
Heahhcare System
The Stale vni\'CrSil\' of New York
at Buffalo

If)

Buf{tdo Pl11 sician IS published
quarter\) b\' the State UmverSil)' of
Ne" York at Buffalo School of
Medicine and Biomedical Sciences
and the Office of Pubhcauons. It IS
~cnt , free of charge , to alumni , faculty .

students, reSidents, ami fnends . The
staff resenes the nghtto ed1t all cop\
and submissions accepted for
pubhcauon
Address qucsuons. comments , and
submisswns to: The Ednor, Buffalo
Plnsiciwt, State Lmvcrsity of Nc\\
Y~rk at Buffalo, Office of Publi cations , 136 Crofts Hall , Buffalo,
m 14260

Send address changes to: Buffalo
Physician , 146 B10med1cal Educauon
BuHdmg, H 35 'Vtam ~lreel, Buffalo ,
NY 14214.

Dear Alumni and Friends,
As I POI&gt;..;TED OUT TO THIS YEAR's INC0\11NG \1EDICAL STL&gt;DENT'&gt;, these are
rapidly changing times, and the task of meshing the art with the
science of medicine is becoming ever more challenging. Voltaire is
said to have observed, "The art of medicine consists of amusing the
patient while nature cures the disease"; yet the scientific basis of
medicine continues to expand and now offers glimpses of disease
mechanisms and body function that provide new and exciting vistas
for the healing arts. But as Victor McKusick noted on a visit to Buffalo,
"There is a widening gap between how to diagnose and how to treat,
and between what we think we know and what we really know." I
suspect that this statement is as valid today as it was just five years ago.
We can take solace, however, in the fact that the quality of our entering class has not
only been maintained but-no offense, alumni!-actually improved. Our curriculum has
also changed: While it still has many of the traditional features familiar to most of our
alumni, the new Clinical Practice of Medicine (CPM) and Scientific Basis of Medicine
(SBM) courses introduce the art of clinical problem solving through the mechanism of
self-directed learning. This should not only add a little excitement to the curriculum but
also better equip our students to become "lifelong learners."
Finally, we look forward to welcoming Stephanie Unger as the new editor of Buffalo
Physician. A senior editor and writer with the City of Hope ational Medical Center/
Beckman Research Institute, in Duarte, CA, Ms. Unger will come on board in October. In
the meantime, a very special thanks to Judson Mead, editorial manager of the UB
Publications Office, for serving as interim editor.

/ ~ .127_/
~f/L~
c:;7' JInterim
Wright, M.D.
1~~~;R. Dean,
School of Medicine and Biomedical Sciences
Interim Vice President for Clinical Affairs

Dear Fellow Alumni,
THE CLASS OF 2001, CONSIST\ G OF 135 FRESH\1.\"1 medical students, has
embarked on an exciting journey. It is a bit shocking to realize that
they will complete their basic medical school education in the next
millennium.
I'm sure I speak for all alumni in expressing my appreciation for
the extensive skills and energy of interim dean Dr.john Wright. I look
forward to his continued participation, counsel, and guidance as he
works to maintain and improve the quality and status this medical
school has achieved over the past two decades under the leadership
of former dean Dr. john Naughton.
This year we are excited about a new mentoring program, conceived by Dr. Wright,
in which interested freshmen will be matched with alumni volunteers who will act as a
friend and mentor, as well as serve as a source of information, advice, and assistance. I can't
think of a better way for students to get to know the alumni and our association. We
already have more than 100 students from the freshman class, and judging by the numbers
of alumni volunteers, they seem to be equally enthusiastic. If any alumni who have not
been contacted would be interested in participating in the mentoring program, please
contact the Medical Alumni Association office. The mentoring program committee is
being chaired by past Medical Alumni Association president Dr. jack Coyne.

~.,;;w, ~D~

President, Medical Alumni Association

�V OLUME

3 1,

N UM B E R

4

A UTUMN

4

Dr. Mahoney
Becomes Dr. Mahoney

8

DNA on Ice
ROSWELL PARK ' S

DNA

LIBRARIES-FROM

G IVING UP A

SILKWORMS TO

PLASMODIUM VIVAX.

by Jessica Ancker

CAREER IN

1 997

"The Woman's
Way of Seeing
and Doing"

12

PUBLIC HEALTH FOR

REFLECTIONS ON

MEDICINE.

PIONEERING WOMEN I N

by Michael Beebe

MEDICINE AT UB.

by Christopher Densmore

Research
GAIT-RELATED PROBLEMS.
PESTICIDES AND BREAST

CANCER.

HIGH CHOLES-

TEROL AND STRESS .

Orientation '97
LET THE HARD WORK BEGIN!

Development
Medical School News

MEDICAL SCHOOL REUNION

A Student's
Perspective
LESSONS FROM THE

GIVING PROGRAM.
MINI MED SCHOOL.

LATE MIDDLE AGES.
P AG ANELLI HONORED .

PET

CENTER GRANT. MAGGIE

Alumni News

WRIGHT RETIRES.

TONE .JOHNSON .JR .

DEAN'S

ADVISORY COUNCIL. UB

COMPLETE S WHI E NROLLMENT .

by Judith Toski, Class of 2000

'75

AWARDED BRONZE STAR.
1 9 9 8 SPRING CLINICAL
DAY

PLAN S.

Classnotes

�mr·

.................................................................................

UB researchers study gait-related problems
ALTERED STRIDE MECHANICS MAY LEAD TO SECONDARY INJURIES

sing a force-measuring treadmill
called the Gaitway, developed by
the Kistler Instrument Corp. of
Amherst, Y, in conjunction with
the UB biomechanics laboratory ,
UB researchers are looking at two
distinct kinds of gait mechanics: running after a leg injury , and walking after
hip-replacement surgery.
RLN"'ING INJLRIES

One area of interest is the relationship
between initial and secondary injuries
in runne rs .
Harold Burton, Ph.D. , UB associate
professor of physica l therapy and nutri-

~ tion and exercise science, and his
: coinvestigator on the study ,john Leddy,
"' M.D., associate director of the UB Sports
Medicine Institute, have been able to
show that runners who develop a muscle
injury in the lower extremities alter their
running pallerns unconsciously after
an injury. This change in running mechanics causes a deviation in the foot's
normal impact and push-off force , which
can be measured on the treadmill.
A change in running mechanics may
affect the way that force is dissipated. As
a result , the added or altered forces are
absorbed by joints and/or muscles unaccustomed to this stress, which may
lead to a secondary injury in areas such
as the knee , hip , or lower back.
"By getting an idea of how a person
with a particular problem changes running strategy, we hope to eventually
identify a pattern and predict the risk
and location of a secondary injury,"

0

Burton says. "If we can predict what's
going to happen , intervention with corrective measures , such as an orthotic,
can prevent the secondary injury from
occurring."
The study, which involved 10 male
recreational runners , examined the effect of injury to the thigh muscles. After
coll ecting baseline measurements during level treadmill running, researchers
had the participants induce muscle "injury" by running downhill for two 20minute sessions. Downhill running can
cause microscopic muscle-fiber tears.
For four consecutive days following the
injury session, researchers recorded the

walking pallern a patient has developed
to cope with the pain of arthritis.
According to Scott White , Ph.D., associate professor of physical therapy
and nutrition and exercise science, relearning a proper walking pallern helps
to prevent injuries after surgery and
speeds rehabilitation .
White is using a Kistler treadmill
equipped with a computer that displays
measurements of force for patients to
read as they walk. When reinforced by
verbal coaching from a physical therapist, the visual aids can help patients see
the problems with their gait and get
immediate feedback on improvements.

vertical foot-ground reaction force generated by each runner during level treadmill
running. Results showed that the runners
who got sore, or "injured ," after running
downhill produced altered forces during
the next running session, indicating alterations in running mechanics.
"These altered mechanics may predispose the individual to secondary injuries of other structures, such as joints,
ligaments, and tendons ," Burton says.
Among runners , this is no small problem. According to Burton, 50 percent of
the people who run regularly experience some type of injury during any one
year and need more education about
what can happen as a result.

A patient with a pronounced limp ,
for example, can be shown two rectangles that represent the relative lengths
of the strides he makes with his right
foot and with his left foot. By trying to
make the two rectangles match in size
as he walks, the patient learns what the
correct, symmetrical walking pattern
feels like.
The Gaitway system's software also
lets researchers record the data and perform a number of different analyses.
In a three-year study funded by the
Arthritis Foundation, White is testing
the technique on a prototype Gaitway
machine , working in collaboration
with Robert Lifeso , M.D., clinical
professor in the Department of Orthopedic Surgery, who performs hipreplacement surgery and often refers
his patients to White's group for postoperative therapy. +

HlP REPLACEMEt\TS

Hip-replacement surgery can take care
of the pain and immobility associated
with arthritis, but many times it fails to
correct a related problem-the cramped

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physician

B AKER

AND JESSICA A NCKER

Autumn

1

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.

Study questions breast-cancer High cholesterol boosts blood
risk trom pesticides and PCBs for pressure in high-stress situations
women who breast-feed
eople with normal blood pressure
n research involving 154 postmenopausal women with breast cancer
and ] 92 healthy \\Omen of similar
age selected randomly from the general population, Kirsten Moy ich,
Ph.D., research instructor in the UB
Department of Social and Prcvcnti,·c
Medicine and chief investigator on the
study, has found no link between breastcancer risk and exposure to pesticides
and PCBs in \Yomcn who breast-fed.
Researchers measured blood levels of
certain organochlorines-DOE, HCB,
mircx, and PCBs. Since these compounds
arc stored in body fat and arc not easily
broken dm.,n , they accumulate in the
body over time. Some of these chemicals ha\ c been shown to increase estrogen activity in animals and consequently
have been linked to breast-cancer risk.
\\'hen separated into groups according to histor) of breast-feeding, .,.,-omen
'" ith breast cancer who had never breastfed had significantly higher levels of
organochlorines than healthy women
who had nc,·cr breast-fed.
"These chemicals arc stored in fatty
tissue, including breast tissue ," Moysich
savs. "The chief mechanism for climin;ting them from breast tissue is lactation , .,, hich Oushcs them from the
svstem." She adds that even though
tl1c nursing baby is exposed to these
substances, the beneficial effects ofbrcastfccding appear to outw cigh potential
risks associated '' ith these organochlorines.
The study
was p rcsc n ted
at the International Socict} for
Environmental
Epidemiology
in Taiwan in
August. +

---

B

u

f

f

0

I

0

can experience greater increases in
blood pressure during stressful
situations if they have high cholesterol, according to a study published by Bong Hce Sung,
Ph.D., UB associate professor of medicine, in the
june issue of the
American journal of
Hypertension. Conversely , the study
found that lowering
cholesterol with
drugs and diet also
lowers stress-related
increases in blood pressure.
It is the first study showing a link between cholesterol
levels and hypertension.
"We don't know the cause of high
blood pressure in 90 percent of
hypertensives," Sung says. "These findings shed some light on the mechanisms
that cause high blood pressure, opening
up possible new avenues for treatment
and prevention.
"Our results indicate that lowering
cholesterol may have the added benefit
of controlling blood pressure better during
stress, which will lower the chances of
developing hypertension and heart disease."
The effect of cholesterol on vasoconstriction has been well documented in
isolated peripheral vessels, but until now
the o,·erall effect of cholesterol on blood
pressure has not been studied.
To assess the relationship between
high cholesterol and blood pressure,
ung and colleagues established a study
group composed of 70 people with normal blood pressure, 33 of whom had
normal cholesterol and 37 with high
cholesterol. Blood pressure was monitored in both groups while they took a
mental arithmetic test , a standard
method to simulate psychological stress.

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Researchers added stress to the equation, Sung says, because a dramatic
increase in blood pressure during
physical or mental challenges has been
shown to be a risk factor for later
development of hypertension and cardiovascular disease. Recent evidence
also shows that the damage to organs
caused by hypertension is more closely
linked to blood-pressure response
to stress than to "casual"
blood pressure.
Results showed that
during the stress test,
systolic blood pressure increased to the
hypertension range
(greater than 140 mm
Hg) in 46 percent of
the high-cholesterol
group, compared to 18
percent of the normalcholesterol group.
Sung says that high cholesterol
appears to impair the ability of the
endothelium (blood-vessel lining) to
relax and constrict normally.
The study's second phase was designed to determine if lowering cholesterol lowers blood-pressure response to
stress. ln a double-blind design, half of
26 members of the high-cholesterol
group took a cholesterol-lowering drug
for six weeks, while the other half received a placebo; the protocol were
then re,·ersed. Total cholesterol fell 26
percent during drug treatment.
Participants repeated the mental arithmetic stress test after both the drug
period and the placebo period. Results
showed that peak systolic blood pressure during stress dropped from 141
mm Hg without treatment to 133 mm
Hg after treatment.
Sung's coauthor on the study were
joseph L. lzzojr., M.D., UB professor of
medicine and professor of pharmacology and toxicology, and Michael F. Wilson, M.D., UB professor of medicine. +
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are key to progress
in genetics research
If DNA is the book of life , the laboratory of
Pieter dejong , Ph.D. , is the printing press .

BY

JESSICA

PHOTOS

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He and his colleagues in the Human Genetics Department at Roswell Park Cancer Institute are the world's
leading suppliers of the DNA libraries that make genetics
research possible.
They have supplied the gene libraries in which the two
breast-cancer genes (BRCA1 and BRCA2) were identified in
1994 and 1995, as well as a host of less
ANCKER
famous genes involved in such illnesses as
C .
KRATT
spinal muscular atrophy , pancreatic tumors, and Wilm's tumor. More than 40
research centers in 10 countries are using dejong's libraries
to hunt for specific genes , create gene maps , or sequence
large stretches of human D A.
Their work makes them a crucial participant in the
Human Genome Project. They're also applying their methods to a wide variety of other organisms, building libraries
of the DNA of mice , rats , baboons , silkworms , the
Legionnaire's disease organism Legionella, and the malaria
parasite Plasmodi um vivax. They're even working with
genetic material from a Doberman pinscher that suffers

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�library and its copies occupy three tightly packed seven-foot
freezers. "So, clearly, you can see that one of the things we
need is technical improvements so the libraries will take up
less space," de j ong says.
The libraries are shipped to researchers all over the world.
One of the biggest advantages of using a standardized library
is that it provides a common reference system. lf, for example, a scientist identifies a disease gene made up of several
fragments from de jong's DNA library, other researchers
anywhere in the world can verify the work by placing an
order with de jong for copies of those bacterial colonies.
A LTER

from narcolepsy, supported in part by a grant from the
American Kennel Club. "ln this lab, you get calls from the
strangest places," de jong says.
CR EAT ING LIBRA RIES

ln de jong's lab, human chromosomes are cut into pieces
between 100 and 300 kilobases long, and the pieces are
linked to fragments of artificially produced bacterial D A.
The resulting circular chromosomes are made up of mostly
human D A but also include important elements that allow
them to "pass" as bacterial chromosomes when they are
inserted into bacteria. One of these is a D A sequence that
ensures that whenever the bacterium divides, it will produce
copies of the artificial chromosome for the daughter bacteria.
These bacterial artificial chromosomes, or BACs, are inserted into specially bred strains of the common bacteria E.
coli. When the bacteria are properly cultured and separated,
the result is an array of hundreds of thousands of separate
bacterial colonies. Each colony, which is tagged with a
unique identifying number, contains hundreds of copies of a
unique fragment of human D A. Together, all the colonies
are known as a library.
Building the library is tricky work. At each step, many of
the bacteria die from the unusual stresses imposed upon
them. For example, electric shocks are used to punch holes
in bacterial membranes so the BACs can enter-and the
shocks are strong enough to kill a substantial portion of the
bacteria. "At each step, we have a rather narrow window of
opportunity," dejong points out.
The library can be stored indefinitely by freezing in glycerol, or it can be copied by a "printing press" that dips a tiny
metal spike into each colony, picks up bacteria, and touches a
clean well of agar where the bacteria will grow and form a new
colony of clones genetically identical to the mother colony.
Dejong's lab makes 12 copies of each DNA library in order
to accommodate requests from future researchers; a single

ATE SYSTE MS IN v ENTED

Although there are many ways to build aD A library, most
have serious drawbacks. Some techniques package the human D A fragments into viruses, which then infect bacterial
cells. But to fit in the viruses, the human DNA has to be cut
into very tiny pieces; and since human genes may be as long
as 1,000 kilobases, it's not very useful to have to cut the D A
into fragments of only 15 kilobases or so.
The invention of the yeast artificial chromosome, or YAC,
overcame the size problem, but introduced other difficulties.
YACs, which are grown in yeast, can be used for fragments
of several hundred kilobases-large enough to contain an
entire gene, or at least a substantial portion of one. However,
up to 60 percent of these fragments are altered in unpredictable ways in the yeast. Sometimes, two or more pieces of
human D A become inserted in the same YAC, making
unrelated human D A sequences appear to be neighbors.
Other times, the YAC D A gets rearranged or combines with
other YACs inside the yeast.

�~(~[ll[~

~(~(~H~

Today, de Jong and many other scientists usc a system
based on the bacterial artificial chromosome, or BAC. ABA
can accept large fragments of human D A, and bacteria
faith full} reproduce them without confusing rcarrangemcn ts
or recombinations.
Dejong also uses a libra[} system he invented several years
ago, a variation upon the BAC called a PAC because it uses
some fragments from an organism called the rl bacteriophage. His PAC librar) is being used b) researchers all o&lt;.er the
world, including the world's largest gene- equencing center,
the Wellcome Trust Centre for Human Genetics, in England.
"They sequence more than all the other centers put together,
and they use our PAC libra[} exclusively," dejong says.
ETHICAL TROUBLES RESOLVED

The Human Genome Project was in full swing, with research
APPLICATIONS I
CA CER RESEARCH
delving into four major D A libraries (including dejong's),
Libraries from Roswell Park haw already been instrumental
when an international dispute broke out about ethical probin Identifying the t\\o known breast-cancer genes and in
lems involved in the collection of the D A samples. It was
studying man} other cancers.
discovered that the samples in the libraries were not taken
In an example from Roswell Park , dcjong's PAC library is
from a cross section of the population, but from a few donors
helping to pin down precise information about the chromowho worked in the laboratories, and that these donors had
somaltranslocations that cause leukemia.
never signed informed-consent releases. Also, no measures
Peter D. Aplan, M.D., a member of the Ros\\cll Park
had been taken to safeguard their anonymity, leading to the
faculty and a B assistant professor of pediatrics and of
possibility that they could run into trouble obtaining health
microbiology and immunology, says that many research
insurance if any genetic anomalies were discovered.
methods can provide some information about these transloThese problems arose when the researchers who were
cations, but only molecular biology can pinpoint the exact
building the libraries treated
places where chromosomes
the human samples as they
break and rejoin. "We want to
Some ethicists fear that genetic
would samples from other ornarrO\&gt; it down to the precise
information will lead to the temptation
ganisms. "The focus was not
base pair ," he says.
on the individual. It was on the
Aplan and his colleagues
to tinker with the human genome.
species," de Jong says.
compare D A from leukemia
cicntists involved with the
patients \l-ith DNA from de
Human Genome Project also worried that they would be accused
jong's PAC library. B} subjecting both to digestion \\Ith
of elitism for studying only the genes of fellow scientists.
restriction enzymes , and then comparing the patterns of
In response to the findings, the ational Institutes of
resulting fragments , the researchers can narro\\ down the
Health awarded grants to build a new set of libraries that
location of the break-point to a region of less than l ,000 base
comply with strict guidelines. Dejong's group was awarded
pairs. This region is small enough to be sequenced in an
$1 million to build two new libraries, one of DNA from a
automatic D A sequencer.
woman's white blood cells, the other from a man's. Dozens of
"Pieter' Pl clones provide a framework that we usc to
volunteer rc ponded to an advertisement in the Buffalo
map our findings onto ," Aplan sa)S.
cws, and after screening by Roswell Park's genetic counseUsing methods like these, Aplan has identified and charlor, 20 men and20 women were selected as potential donors.
acterized a nm·el gene that , when disrupted by translocaThe final selection of blood samples was made on a doubletions, apparently helps to cause T-cell acute lymphoblastic
blind basis, so neither the volunteers nor the scientist know
leukemia. He has also studied the mechanisms of action of
whose genes are in the new library.
distorted gene products im olvcd in other leukemias and has
The male D A library hasjust been completed; the female
proposed an explanation for ho\\ chemotherapy for a prione is next. Meanwhile, the old libraric may still be used
mary cancer can trigger therapy-related acute myeloid leukemia many } cars later.
because the donors signed consent form , de jong says.

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Cancer is not the only target. By studying inheritance patterns in an extended family, researchers at ew York University have narrowed down the location of a potential epilepsy
gene to a region of aboutSOO,OOO base pairs on one chromosome. They can go no further with gene mapping, so they
have approached dejong about making aD A library from
a particular patient thought to have the gene.
And many of the world's most prominent genetics research centers, including the Wellcome, the Whitehead
Institute/MIT Center for Genome Research, and the Sanger
Centre in England, are using dejong's libraries to sequence
human D A as part of the Human Genome Project. Each
segment of human D A is subdivided until it is small
enough to be analyzed by an automated D A sequencer.
Some 16,000 of the estimated 50,000 to 100,000 human
genes have been mapped, but the function of many of these
genes is still unknown. A comprehensive sequence of the
human genome will reveal many more unknown genes, so
the next step must be to investigate their function through
such techniques as comparing them with homologous genes
from other organisms.
There are many questions about the best uses of the new
genetic information. Some ethicists fear that it will lead to
the temptation to tinker with the human genome for trivial
or monetary reasons.
But Thomas Shows, Ph.D., chair of the Department of
Human Genetics at Roswell Park, is optimistic that complete
information about human genes will focus medicine on what
he calls "preventive maintenance."
"We could become predictors of disease," he says. "Preventive medicine is so much less expensive than treating
disease after the fact. "
Prenatal testing can already identify more than 200 genetic
disorders. Ultimately, Shows hopes, physicians will be able
not only to identify potential problems but to prevent them.
"Genetic testing might allow
DNA library plates are stored
us to find out what cards we're
at -85 degrees Celsius.
dealt with in the game of life," he
says. "Do we have a royal flush ,
or a couple of two's? Whichever,
we need this information to play
the game." +
For more informoHon obout BACs ond PACs, visit Pieter
de Jong's Web site ot http/ jbocpoc.med.buffolo.edu.
j essica Ancl1er, a Cleveland-based
freelan ce writer, is tlte fann er editor of
Buffa lo Physician.

1. Extract DNA
Human white blood cells are
embedded in agarose, then
digested with enzymes, leaving the DNA behind in the
agarose gel.

How to
Build a DNA
Library:
THE RECIPE

2. Cut up DNA
The DNA is incubated with a dilute solution of restriction enzymes, which cut the
chromosomes at specific nucleotide sequences, producing a pool of DNA fragments of different lengths.
3. Select fragments
In gel electrophoresis, small DNA fragments embedded in a gel move through an
electric field at speeds proportional to their size. In order to separate large
fragments, the orientation of the electric field is changed every few seconds in
a process known as pulsed-field gel electrophoresis. Fragments of the desired
size-] 00 to 200 kilobases-can be isolated using this process.
4. Build artificial chromosomes
The DNA fragments are linked with the vector DNA to make circular bacterial
artificial chromosomes, or BACs. Naturally occurring enzymes are used to seal
the pieces of DNA together.
S. Insert into bacteria
Ashock of a few thousand volts of electricity creates a hole in a bacterium's
membrane that lasts long enough for a BAC to squeeze inside, a procedure called
electroporation.ln order to create enough holes in enough membranes, the jolt
must be strong enough to kill a substantial fraction of the cells.

6. Weed out failures
Only a few of the surviving cells will have successfully taken up BACs. Each BAC
has been constructed with agene that confers resistance to a particular antibiotic.
By exposing the E. coli to that antibiotic, the researchers can kill off any cells that
don't have a BAC inside.

7. Grow colonies of clones
The surviving bacteria are spread thinly over plates of growing medium and
allowed to reproduce. Each colony will be made up of the genetically identical
descendants of a single bacterium.
8. Plant colonies
Arobot identifies the round white colonies, picks asample from each, and plants
the samples in the library plates. Each library plate, which is about the size of a
large index card, has 384 tiny wells filled with growing medium and thus can
support 384 clones. Each well is identified with a unique address, and each plate
is labeled with a bar code. An entire human genome library will contain more
than 500,000 clones and fill some l ,500 plates.
9. Store or reproduce
The plates can be stored indefinitely at -85 degrees Celsius. The colony-picking
robot can also act as a "printing press" to make copies of the plates.

�MARTIN MAHOI\L\ \\'.\~ON Ill.,\\;\\

to a stellar career in the field of public health as an
epidemiologist whose doctoral dissertation revealed higher-than-expected cancer
rates among Seneca Indians and as director of ew York's cancer-surveillance
program-all before he reached the age of 30. He also had teaching appointments in
the School of Public Health at the State University of ew York at Albany and in the
Roswell Park Cancer Institute's graduate division.
Arthur Michalek, Ph.D., a leading cancer researcher at Roswell Park who first had
Mahoney as a student, then later conducted groundbreaking research with him,
recalls that he had the makings of "a leader in the field."
So what is Mahoney, now 35, doing with a stethoscope around his neck, checking
a youngster's sore throat, asking an elderly patient how that new medication is
working, and seeing anyone who comes in the door of the family practice clinic at the
relatively low-profile DeGraff Memorial Hospital in orth Tonawanda, ew York?
Mahoney, who still carries the oversized shoulders of a competitive swimmer from
his undergraduate days at Canisius College, smiles at the question.
"It's something I always wanted to do," he says. He obviously wanted to do it
pretty badly.

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FROM
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PRIMARY
CARE
~--------------------------------------~

WHEN HE FIRST APPLIED

to the University at Buffalo medical school in 1983, after graduating

with honors in history from Canisius, he was not accepted (true of about 90 percent of those who
apply). His grades were good, his board scores were okay, and he had taken the necessary science
courses despite his history degree. He just wasn't close enough to the front of the line.
David Valai k , Ph.D., his history professor as well as his
swim coach at Canisius, doesn't think much of a medical
school admission committee that would reject Mahoney.
Valaik couldn't have asked for a better student or swimmer. Last year Mahoney was the first swimmer since Canisius
started its swimming program in the 1960s to be inducted
into the college's sports hall of fame. "Martin never needed
the lecture 1 give to some students," Valaik says. "He had it. "
Without the option of attending medical school, Mahoney
decided to study epidemiology, earning both a master of
science degree and a doctorate at UB before going to work
with the ew York State Health Department in Albany.
As director of the state's cancer-surveillance programs,
Mahoney found both rewards and frustrations in public
health. He suddenly had access to millions of health records
and powerful computers to analyze the data . He traveled
throughout the state, looking at clusters of cancer and trying
to find relationships . But as he discovered in May 1989 , there
are limits to what an epidemiologist can do .
Mahoney came from Albany to orth Tonawanda with
the results of his latest study, a look at cancer cases near a
plastics factory. A nine-year survey of local medical records
showed cancer was not on the increase. lt was not what the
hostile audience wanted to hear .
"We are not going to buy that ," said the city's mayor at
the time , Elizabeth C. Hoffman , who had ovarian cancer
herself. " ot when people see house after house with
people with cancer."
Mahoney felt the call of medicine and its more immediate
results even more strongly after he first gained the confidence of the Seneca Indians and then published his study
showing that cancer rates were much higher among that
ative American population than expected. The study, and
later work by Mahoney , Michalek, and others, showed that
while cancer deaths increased by 4 percent in the general
population, they jumped by 10 percent among ative Americans, who have the poorest cancer survival rates in the
United States. Yet health-care providers to these Indian
populations gave cancer a lower priority behind alcoholism,
diabetes , injuries , and cardiovascular disease.
"As a researcher," Mahoney says, "l thought it would be
easy to implement. But I didn't see anyone jumping on it. "
So in 1990, Mahoney again applied to medical school and
this time , armed with credentials that most medical schools
would die for, was easily accepted.

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Mahoney's first rejection was reall y not unusual, says
Roseanne Berger, M.D., associate dean for graduate medical
education at the UB Medical School. "Despite the questions
in the press about whether we're training too many physicians or whether income is going down , the number of
applications to medical schools continues to increase. The
talent pool is really remarkable ."
But going to medical school and interrupting a successful
career to do so is difficult, as Mahoney found out.
He and his wife, Ellen, were expecting their first child
(their daughter Christine is now 6), and they had to sell their
home in Albany and go apartment hunting in Buffalo.
Mahoney also had to give up a good income with the state
and face stiff tuition bills again. His wife was behind him all
the way.
"Why not do it? " he says. "I figured this was always going
to haunt me if I didn't."
To put it mildly , Mahoney was not your typical medical
student. He kept his teaching appointments at SU Y/Albany
and Roswell , continued his research with his mentor
Michalek, and picked up a part-time job as a medical
epidemologist with the Buffalo Otolaryngology Group. "T hey
were sitting on a large amount of data from their patients
over the years, and I helped set up a database," he recalls.
Mahoney, who received one of the public-health industry's
most prestigious honors in 1992-thejay S. Drotman Memorial Award-for his pioneering research with the Senecas, also
started making a name for himself in national medical circles.
He was elected first as a student representative, then later as a
resident representative, to the American Academy of Family
Physicians' Commission on Public Health. Then this past
spring, he received the American Medical Association's
Glaxo Wellcome Leadership Award, the resident's award from
the ew York State Academy of Family Physicians, and the
MeadjohnsonAward for graduate education in family practice.
Described by those who know him as soft spoken but
vocal when he needs to be , Mahoney seems almost embarrassed by the attention . "I guess I've just been fortunate to be
recognized for some of my accomplishments," he says.
Mahoney feels that his public-health background is invaluable when searching for the cause of a patient's illness in
the clinic. Like epidemiology, he reasons , medicine is a case
of examining a problem thoroughly and then reducing the
odds. If it's not this, it could be that; if you eliminate this , it
might be that.

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Practicing medicine, in the same way, is helping him with
his research.
While serving part of his residency in the Deaconess
Hospital, where he saw a mostly minority, low-income
population, Mahoney noticed that many of the new mothers
were not nursing their babies.
"Physicians are naturally inquisitive, and would probably
notice this and say something about it to their fellow physicians or spouses," says Berger, the associate dean and
Mahoney's ultimate boss during his residency. But Mahoney's
public-health background gave him the expertise and confidence to follow his curiosity and develop a questionnaire
and a database to further study the reasons behind this
phenomenon, she says.
Noting that the results are still coming in, Mahoney says
that it appears that breast-feeding in these women is not
something that is passed down from one generation to
another, perhaps because they have children at such an early
age and the generations pass so quickly.
His work at Roswell Park Cancer Institute, where his
research partners include Michael Cummings, Ph.D., one of
the nation's preeminent antismoking experts, has led him to
what he feels is one of his most exciting projects: Tar Wars.
Conceived by two Denver physicians and run in past
years on a shoestring budget, Tar Wars has been adopted and
funded by the American Academy of Family Physicians.
Mahoney serves on the Tar Wars board of directors and is its
coordinator in Western ew York. ''I've really bought into
this," Mahoney says. "I think it's a terrific program.
"You can't tell kids that smoking is going to shorten their
life and that they may die when they are 40, 50, or 60 years
old," he said. "When they're l l or 12, they think they're
going to live forever. So we mention the negative effectsbad breath , yellow teeth, smelly clothes. Plus smoking costs
a lot of money. It begins to get them to focus on how
advertisers set them up. You never see these effects of
smoking, or ashtrays or burns in the clothes in the ads. We
get them to figure out how much smoking costs, about 60
or $70 a month. That's a small fortune for a kid-that's three
CDs and a in tendo game."
Mahoney intends to hit the road this year to spread the
message of the Tars Wars campaign in classrooms.
It's not that he has a lot of free time. In addition to his
work , Mahoney and his wife now have two other children,
icholas (5) and Madeline (15 months). He also is the
medical director for the Cantalician Center for Learning; a
board member of the Allegany Regional Development
Corporation, which helps serve the Seneca ation of Indians in Salamanca, Y; and a board member for the iagara
Frontier Vocational Rehabilitation Services, a group that
trains and finds jobs for disabled people. And for the past
year, he has served as vice chair of the residents section

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representing family physicians on the national Council on
Medical Specialty ocieties. He is a founding member and
on the steering committee for the etwork for Cancer
Control Research in American Indian and Alaska Native
Populations. In addition, he serves as a referee for five
professional journals, including the Intcmationaljou rnal of
Epidemiology, and he i an author, coauthor, or contributor
to 57 research projects.
"My wife understands my work," he says. "She knows this
makes me happy. I'm one of the luckiest people in the world."
Mahoney has just completed his residency-he also was
chief resident-and signed a contract with the medical
school, one that allows him to practice medicine, teach
medical students, and continue his research. 'Ttl spend 60
percent of my time in clinical work, supervising residents
and seeing patients. Twenty percent of the time I'll teach, 10
percent for administration, and 10 percent for research. That
doesn't sound like a lot of research, but right now I'm doing
all my research on my own time."

It would have been simpler, of course, had Mahoney
gotten into medical school the first time. But now that he's
completed the training for his dual careers, he wouldn't have
it any other way.
His former mentor, Michalek, who has developed a deep
friendship with Mahoney, says his medical degree helps
Mahoney bring a fresh perspective to the public-health field .
"I think he'll have the best of both worlds," Michalek says.
"An M.D. has a real appreciation for the clinical approach.
Most people in public health may have a Ph.D., but they don't
have an appreciation for disease. That clinical training gives
him the ability to better evaluate the research ."
It also has a beneficial side effect for Michalek: After all
these years of teaching medical students, Michalek has
finally chosen one to serve as his own personal primary-care
physician-Or. Martin C. Mahoney, Ph.D., M.D. +
.\1ichacl Beebe is a reporter for the Buffalo

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�MEDICAL STUDENTS

�"DOES THE WOMAN'S WAY OF SEEING AND DOING EVER HANDICAP HER?"

BY

CHRISTOPHER

DENSMORE

, 'E HtJNDRED YE-\RS&gt; AGO ,

-

on April 27, 1897, Dr. Maude j. Frye addressed the

graduating class of the University of Buffalo School of Medicine on the subject of "The
Woman's Place in Medicine." An 1892 graduate of the medical school, in 1897 Dr. Frye
was on the faculty as a clinical instructor in the diseases of children.
I am going to use Dr. Frye's address, along with the recollections of UB's first female
medical school graduate, Dr. Mary Blair-Moody, and editorials of Dr. Austin Flint that
appeared in the Buffalo Medical]oumal, to illuminate the experience of these pioneering
._.

women medical students. I will use, as much as possible, their own words. First, Dr. Frye:

"I WISH TO PRESENT to you tonight some thoughts
concerning woman's place in medicine; the limit of her
work, [and) the line which she will oftenest follow.
"Whether we like to confess it or not, woman's physical
organization necessarily sets a limitto her achievements ...
[Here Dr. Frye refers to the proposal that women serve in
the National Guard. She is a bit skeptical.] In reckoning the
chances of woman's success when she comes into competition with man, the physical factor has always to be taken
into account. That medical work which makes the least
demand on woman's physique is, other things being equal,
that in which she will best succeed."

In looking at the past, it is sometimes apparent that
beliefs can change. One of the hot topics of the
medical literature of the 1890s was whether women
should ride bicycles: Would the exertion harm them?
Of possible relevance here is an illustration in the first
UB yearbook (the Iris), in 1898, of a woman with a
bicycle waving a UB pennant. ow back to Dr. Frye:
"IT IS, HOWEVER, concerning a feature of woman's
mental equipment for work in medicine that I wish especially to speak. I do not expect many of you to agree with
me, yet I ask you to think on these things. We must
acknowledge between the average man and the average
woman an unlikeness of mental capacity comparable to
their physical unlikeness, a sex in mind, if I may use the
term. This is not equivalent to saying that man is superior
to woman. There is equality with diversity. The elm is not
better than the oak, nor the oak than the elm, but each is

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good of its kind. There are mental processes which are
identical in the sexes, there are others which may
oftentimes give advantage to the woman in the work of
the physician. Does the woman's way of seeing and doing
ever handicap her? Let us try to answer the question."
lt was this last sentence that first got my attention. A gendered way of "seeing and doing?"
Sounds like Men Are from Mars, Women Are from
Venus, and other books of that ilk. The debate
about whether men and women are essentially the
same, or essentially different, has been going on
for some time, with, so far as I can see, little chance
of final resolution. But to return to Dr. Frye:
"IN THE EARLY DAYS when the woman who began
the study of medicine was of heroic type, her success was
assured from the beginning, for the courage which dared
to commence the struggle was equal to any hardship or
any emergency which arose later. She has opened the
way for the woman of average ability, the woman who
but for her pioneer work would be teacher or nurse. The
average woman has not, as a rule, the daring of an
Elizabeth Blackwell."

Dr. Frye is speaking to us from a century ago,
1897. Fifty years earlier, in the fall of 1847, Elizabeth Blackwell had become the first woman to
study medicine in the United States when she
entered Geneva Medical College. Or rather, she
became the first woman to be recognized by the

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�medical profession as a physician. Women have
been studying and practicing medicine for a lot
longer than 150 years. We are in fact talking about
the institutional recognition of women as physicians by the medical profession.
Elizabeth Blackwell's story is not unconnected
with the history of the University of Buffalo. In
1847, many of the people who taught at Geneva in
the fall came to Buffalo in the spring to lecture at
the VB medical school. All of the teachers at
Geneva mentioned by Elizabeth Blackwell in her
autobiography were also on the faculty here at UB.
One member of our faculty (who did not teach
at Geneva) was Austin Flint, after whom Flint
Road on the university's North Campus is named.
Dr. Flint was the editor of the Buffalo Medical
journal and an early supporter of what was then
the novel experiment of educating women to be
physicians. ln an editorial published in January
1848, Flint looked forward to seeing women as
physicians, even though he also stated that "We
should regret to see any innovations tending to
lead woman from her appropriate sphere-the
domestic hearth and the social circle-but we can
perceive no good reasons why females whose
duties are not prescribed by domestic or social
relation should be denied ... exercising usefully
their faculties in the capacity of medical practitioners, under proper limitations."
To modern sensibilities, this may seem rather
lukewarm support, but Flint did, in my e LimaLion, provide important upport to Blackwell by
publishing her dissertation in the pages of the
Buffalo Medical journal and by writing approvingly of her progress in the medical profession.
But advances are not always sustained. Flint's
successor as editor of the Buffalo Medicaljoumal was
emphatically opposed to women doctors, and when
Elizabeth Blackwell's sister Emily applied for admission to the VB medical school in ovember 1851, her
application was rejected by the faculty. Women continued to be educated as physicians, but only in such
institutions as the Female Medical College of Philadelphia and the ew England Female Medical College, not at the older male institutions.
UB's true pioneer woman medical student was
Mary Blair-Moody, whose application for admission
to the medical school was accepted in 1874. In 1896
Dr. Blair-Moody's reOections on her own experiences were published in the Buffalo Medicaljoumal:
"EARLY IN THE AUTUMN of 1874 the majority of the
faculty of the medical department of the University of
Buffalo decided to favorably consider an application
made some years before by a woman resident of their

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own city, to pursue the study of medicine in their classes
on the same footing as the male students. Sex was to be
left out of the question as much as possible. The minority,
finding it difficult to wholly approve, yielded with true
American spirit and also welcomed the innovator with
what grace they could command. My youngest brother,
then about passing out of his teens, having just previously decided to pursue the study of medicine in that
institution, became a member of my family, and together
we went into the search for the precious possibilities of
the healing art. Every day we measured our work, not by
what was required, but by what was possible to be done,
making that also include the required. The personnel of
the faculty at that time always recurs to my memory as
being of a somewhat unusually high order. There was a
keen love of truth among them for its own sake.
"Two of them said to me, at different times in the
course, 'Do not believe what we tell you in medicine or
what anybody says until you prove it.' All did not teach in
that way for obvious reasons, especially the demonstrator in anatomy.ltwould be impossible. Professor Hadley's
classes in chemistry had been and continued always to be
open to women. Not only so, women were cordially
welcomed and encouraged to do the best work of which
they were capable. Dr. Mason frequently had women
visitors in his physiology classes and delighted in enlightening them on such practical points as choice of good
respiratory mechanism, effects of certain nervous lesions, and similar branches of the subject.
"After being well started in my work, and having
become quite enthusiastic over the clearness and elegance
with which the professor of surgery, Dr. Moore, instructed
his classes, I chanced to be in one of the other professor's
rooms when he entered without noticing me and exclaimed: 'How is it that we have a woman here?' Dr. Potter
entered at that moment and replied: 'J assume the responsibility.' He was dean at the time, and one of them-1 do
not remember whom-remarked: 'If we do not like it when
she gets through, we can close the doors.' They have never
been closed; but, nevertheless, it is my impression that it
is liable to remain what it was in the beginning, a man's
college, courteously conceding as a privilege to women
advantages not taken into account by its charter members.
"This has its uses; chivalry on one side and gratitude on the other are encouraged. It is like a bit of the
romance of the Middle Ages dropped into the life of a
wide-awake, not to say prosaic, American city. Some
of the professors said when they decided to leave the
doors open to women: 'It shall never be a woman's
college. If they wish to study as the men do, well and
good. We shall not advertise it as a college admitting
women, nor make special arrangements for them, nor
consult their convenience.' One of the professors who
took this stand and maintained it expressed at one
time a thought which is shared by too many and is

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mentioned for that reason: 'No lady will wish to study medicine,
with the emphasis on lady.'
"It was a question in my mind soon after entering how to manage
... I soon felt that there was a majority of the students that would
intelligently sustain fair play in the matter. That was a great help to
me. What I would have done had that sentiment not prevailed in the
class Ido not know.! am sure that this sentiment also prevailed among
the professors. There were a few rough fellows in the class who
occasionally called my attention to themselves by cat-calls when I
entered, excessive smoking at recess, close to my seat, and other
manifestations of ill breeding. The class endured it for a while in
silence, simply attempting to frown it down. It happened, however,
one day that one of the ringleaders of this movement was discovered
in some such trick, I do not know just what, and was doubled up and
handed over the tops of the iron seats from one man to another from
the back row right down to the desk and rolled over that in no gentle
manner to the lecturer's usual place. The quietest, most scholarly, and
most gentlemanly men in the class took hold with a will and received
him with open arms as he was handed along too rapidly to help
himself, starting as he did doubled up like a jackknife. This happened
just before lecture time.lt was done quite sternly, almost silently, and

---- =

and "Of course," recalled Dr. Blair-Moody, "he would not be
just ready when I wanted to go home."
" ... At graduation the announcement was received with rather
more than the usual cheers and congratulations, six little pairs of
hands in the gallery joining in the applause."
By the time Dr. Blair-Moody penned her recollections,
and when Dr. Frye gave her lecLUre, women medical students at UB were no longer an experiment. In the 1880s and
1890s, women made up as much as 15 percent of the
graduating classes. Women would remain a minority until
the 1970s, but their fitness to swdy medicine was no longer
seriously questioned.
On October 17, 1889, the women students at the University of
Buffalo met to consider "the advisability of fonning a society of
women students of the university."
Since the time the college admiued women, and Mrs. Moody
became a student, the effort of coeducation had been a success,
and the time was now ripe for women to bind themselves to
support one another to work, not as a few timorous individuals
upon whom the world should frown disapprovingly, but as a
sisterhood whose object should be mutual
encouragement, support, and aid in matters
social, educational, and
professional.
The organization founded , known only by the initials
S.E.V., sponsored lectures, study sessions, and social events.
Women were to some degree accepted, but continued to feel
the need to create separate organizations for mutual support.
Organizations by and for women at the university have now
been functioning for more than a century.
Returning to the remarks of Dr. Maude Frye in 1897:

iiiiiiiiiiiiiiiiiiiiiiiiiiiiii

must have
noforce,
small
amount
ofrequired
muscular
as he was not a slight fellow
to whom this dose was administered. It amused me
greatly, as the man seemed
to shrink from attracting attention to himself in any way afterward ...
"... John, the janitor, was my faithful friend through it all. He was
always interested in my work, kind and helpful. Among the boys he had
the reputation of being afraid of nothing, living or dead. He, too, liked
to see fair play, at least so far as I was concerned, and occasionally so
expressed himself to the students in his own inimitable way. 'She pays
her money like the rest,' he said to one rough student one day. 'She has
just as good a right here as anyone.'
"But there were limits, by common consent apparently, to my
privileges. It was to be fair play but no favor on account of sex. Our
professor in medicine ... once overstepped the bounds, according to
class sentiment. We were studying diseases of the chest under his
instruction. A prize had been ... offered for the best report on a certain
set of lectures on this subject. Perhaps to try the temper ofthe men and
their opinions on the subject, he called me out at several successive
clinics to make the chest examination, which was a coveted privilege
and could not well be accorded to everyone. About the third time a
hiss of disapproval was sufficiently expressive to convey the class
sentiment of fair play and no favor ... "
Mary Blair-Moody was what we now think of as a "nontraditional" swde nt~older, married , and with children of her
own. When she entered the medical school, she was in her late
30s with six children. She doesn't mention her child-care
arr;ngcments or support network, but occasionally at the end
of a long lecture day her family came down to pick her up, and
the children would sit with her in the upper seats of the lecture
hall. One of her boys would take off his shoes and stockings,

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Physician

"THERE IS ONE quality which more than any other makes for success
in certain lines of medical work. It is the type of courage more or less
common to all men, rarely found in women-the courage which
dares. It is the courage of the soldier, and the explorer. It is the courage
which makes possible the great surgeon."
ote here that Dr. Frye is talking about two forms of diversity
in the mind: a diversity among women, between the heroic
pioneers in the mold of an Elizabeth Blackwell and most
women; and a generalized diversity between men and women.
"ON THE OTHER HAND, through all time woman's genius has
given this character to her work. It has not turned to great deeds but
has contented itself with the humbler, often holier, tasks of the home,
the school-room, and the sick chamber ... It is the courage whose other
name is patient endurance ...
"The lack of daring does not make a physician less trustworthy,
nay rather she may be more worthy of trust, but the lack does not work
to her material advantage. There are departments of medicine,
notably bacteriology, for which not only woman's type of courage, but
her whole manner of training, from her youth up, should eminently fit her,

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�and in such work as this I believe she
will excel. But the woman who gains
wealth and fame in the practice of general
medicine or of surgery will be the woman who
possesses, without necessarily losing anything
of her outward womanliness, the masculine type
of courage. She will be the woman who would
rather be wrong than not try. The
average woman would rather not try
than risk being wrong.
"There is a special message which I
wish to give to the young women
receiving their diplomas tonight. It is
concerning your work among women.
Whether you intend to be a gynecologist or
not, every woman who enters your office
expects you to be. Setting aside your right to
do whatever you can and desire to do, the fact
that women wish women physicians
is the only reason for your being such.
You will come to feel later the great
power for good-not altogether in a
professional way, but as friend and
counselor-which is yours, for the
good woman who is a good physician has before her, in teaching to her sex
right ways of living and true views of life, a
work which will bring satisfaction to herself
and blessing to others.
"... Except for the woman of unusual talent,
wifehood and motherhood are of
themselves a vocation. Because of
this and because other occupations
demanding less of her physically and
mentally and offering quicker success
are open to woman, the number of
women physicians will always be few .
Yet whether we ever occupy a great place in
medicine or not, a place is ours. We are better
women for the knowledge of humanity which
our work has given us. May we not hope that
humankind will be the better too, for
our having wrought!"
Dr. Elizabeth Blackwell continued as a pioneer in medical education for women in the United States
and also in Britain, where in 1859
she was the first woman to "have
her name entered on the Medical Register
of the United Kingdom." She died in 1910.
Dr. Mary Blair-Moody became the
fir t woma n member of the Erie County
Medica l Society, a fellow of th e
America n Association for th e

Advancement of Science, and a fo under
of the [Buffalo] Women's Educational
and Industrial Union. The union later (in
1916) gave their building to house the
new College of Arts and Sciences and
provided an endowment for the university. When asked for her opinion about
th e uses of the endowment, Dr. BlairMoody recomm ended the establishment
of a Departm ent of Preventive Medicine,
"wi th a yo ung, able, gifted , and enthusiastic person as leader. Sex should not bar
anyo ne fro m this chair. " She died in 1919.
Dr. Maude Frye taught briefly at UB,
then went on to a large and successful
medical practice in Buffa lo. From 1922
to 1940 she also served as Medi ca l Adviso r for Women at th e Uni versity of Buffalo. She died in 1946.
Change is so metim es slow. In the
co urse of co ll ecting materials for this
paper, I checked th e Medentian, a magazine published by the students of medicine and dentistry at UB in the 1940s. I
was looking to see if it might have carried
an article on Dr. Frye's retirement.
Though I didn't find one, there was a
regular monthly column written by
women in the medical school under the
ti tie "Hen-Med. " The first issue of the
1939- 40 school yea r, some 50 yea rs after
Dr. Frye ente red the medi cal school,
ended with the following observation :
"THE SLIGHTING FACT that none of the
physical diagnosis instructors at a hospital
(quote) wants a woman in his group (unquote)
... The unflattering fact that women are politely
excused from certain clinical procedures. The
unsurmountable fact that too many hospitals
have doors closed to women interns. Take all
this, give it a quick glance, and pretend to
forget about it.
"Pretend. But do your share to prove your
worth. Remember that the emancipation of
women is still a thing of the future. And here in this
school, as liberal and open-minded in its attitude
toward women as any school in the country,
among a group of genuine good fellows who are
learning to accept you in spite of the remnants of
their traditional distrust of you, is your chance to
play a part in the great emancipation." +

Magnificent
BUILDING LOTS

Dear Colleague:
As a former president of
the University at Buffalo
medical school Alumni
Association and a
practicing surgeon in
Western ew York
for many years, I've
come to understand what members of our
profession desire in a home site - privacy,
tranquility, fresh air, and pristine surroundi ngs.
The Summit at Scherff is a truly extraordinary
residential developme nt, un rivaled in Weste rn
New York. Nestled in the hills of Orchard
Park, this magni fice nt 81-acres has been
subdivided into 50 estate-sized buildi ng lots
surrounded by Chestnut Ridge Park and
euman Creek in a very private enclave.
Specifical ly as an escape from the fast- paced
everyday life we lead, it's features include:
' Spectacular panoramic views of the Canadian
shores, Lake Erie, and the Bulialo skyline
' Mature woods and secluded ravines
• Oversized lots for your dream bouse

' Quick and easy access to the freeway systems
leading to Bulialo and the city's northern suburbs
' Privacy, seclusion, and exclusivity

The Summit promises to be one of the
premier areas in Western ew York to
construct your luxu ry residence. I invi te
you to take a stroll through this picturesq ue
setting. For ou r detailed brochure or a private
showi ng please call (716) 667-2237 or
(716) 472-3790.
Sincerely yours,
Ed mond J. Gicewicz, M. D.
Past President, UB Medical Alumni Association

THE

Orchard Park, New York

CIJristoplt e1 Densmore is tlte University at
Buffa lo arcll ivi .st.

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SUMMIT AT SCHERFF

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~

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Mini med school ahit

LAYPERSONS LEARN HOW EX C ITING AND UNDERSTANDABLE
SCIENCE AND MEDICINE CAN BE

tis 6:30 on an exquisitely beautiful summer evening in late july, and
Butler Auditorium is already starting to fill. By 7:00, Alan Reynard,
Ph.D., professor of pharmacology and toxicology, is well launched
into his description of how R A polymerase forms mR A in order to
copy D A. He is squeezing in the last few minutes of a lecture he began
two weeks before, working his way to the consequences of mutation" ow, is a protein with an incorrectly placed amino acid a mutation? No."
He presents clearly but quickly because Jerrold
Winter, Ph.D., professor of pham1acology and
toxicology, is waiting to present his scheduled
lecture on the chemistry of the brain.
Every UB medical school class for the
past 30 years has sat in these seats and
heard these lectures, although they have
usually been given in more detail. But
tonight the students are a retired electrician and his wife , a systems analyst, an
office manager, a lawyer, 16-year-old
Brandon Palumbo, whose grandfather
wants him to get a taste of what studying
medicine would be like, and 200 other
men and women as unlike in their age
and backgrounds as traditional medical
school students are alike in theirs.

This is the final night of the second
six-week session of UB's Mini Medical
School, developed by Harry Sultz,
D.D .S., M.P.H., professor of social and
preventive medicine and director of
the medical school's Health Services
Research Program.
When he applied to UB's Office of
Public Service and Urban Affairs for a
start-up grant, Sultz knew that such
programs had been successful elsewhere. The first was offered by the
University of Colorado Health Sciences
Center in Denver in 1990; since then,
more than two dozen institutions have
offered similar programs, including
a four-week session for members of
Congress sponsored by the ational
Institutes of Health's Office of Science
Education Policy.
"The real question in our minds ,"
Sultz said recently, "was whether Buffalo , with its reputation for blue-collar
interests, would respond the way other
cities had. "

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Buffalo and its environs responded.
otice of the spring program consisted
of one announcement on UB's FM radio station and an article in the Buffalo
ews. More than 1,000 people called
for the 287 seats. A second program was
arranged for June and July to accommodate some of the overflow. A third
program will run in September and
October, supplemented by additional
lectures-on alternative medicine,
women's health , preventive medicine ,
and how to navigate the health-care
system, among other topics-for those
who have been through the basic course
and want more.
The curriculum for the basic course
consists of two lectures each on the
subjects of cardiology, neuroanatomy
and neurosurgery , microbiology and infectious diseases , oncology, immunology, and pharmacological therapeutics
of the mind.
Sultz, who readily characterized the
program as "pa rt lecture, part theater, "
recruited a luminous faculty of volunteer lecturers . On the night of the last
summer session, as Jerrold Winter describes Otto Loewi's discovery of the
chemical transmission of impulses in
the nerves, the Butler auditorium quiets
to a dead hush .
"The thing that surprises me the
most," Sultz says, "is the interest the
people have in pure science. They're
fascinated by science, even if it doesn't
have immediate practical application to
their own health."
Sultz set three goals when he proposed the program: to promote good
relations between the community and
the medical school, to make science and
medicine more understandable and exciting to laypersons, and to increase
participants' knowledge of health and
disease so they could be more competent health-care consumers.
Continued demand for the basic
course and the interest of"graduates" in
additional lectures suggests that he has

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THE THING THAT SURPRISES ME THE MOST IS THE INTEREST THE PEOPLE HAVE IN PURE
SCIENCE. THEY'RE FASCINATED BY SCIENCE , EVEN IF IT DOESN' T HAVE IMMEDIATE PRACTICAL
APPLICATION TO THEIR OWN HEALTH. "

met the first goal. "We have a number of
science teachers taking the course," Sultz
says, "and they've wanted to know if
they can bring their students. So we're
talking about creating a mini med school
for science teachers and their students
on a model developed by the University
of orth Carolina."
For Charles Gorder, a retired electrician from Clarence, NY, the evenings
have been a taste of what might have
been: "When I was a youngster, I worked
as an assistant to a pharmacist. When I
got drafted during the war, I hoped to be
a corpsman but the avy made me an
electrician. I've been an electrician all
my life-and that's been good, don't get

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me wrong. But I've always had the interest. I've learned more here in six hours
than I did in my entire life in school.
Look at tonight. Now I know that someone who's depressed may be suffering a
chemical imbalance."
Bill Kilinskas, a systems analyst from
Amherst, Y, came because "at my age
you start thinking about health. The
knowledge of what a heart attack really
is, what a stroke really is, is useful. "
And the 16-year-old? "I think it's
pretty interesting." During intermission,
after Winter has finished diagramming
receptors and explaining acetylcholinesterase, serotonin, dopamine,
gamma-aminobutyric, and other features

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of brain chemistry, Palumbo buttonholes him at the back of the hall.
After the first session, Sultz was approached by a local cable television system with an offer to tape and broadcast
the lecture series, but he turned them
down. "I don't want people to take this
sitting in their living rooms. I want
them to go to medical school."
And he rounds out the experience
with a mini graduation. Led by the traditional bagpiper, the robed faculty march
to the well in Bu tier to close the sessions.
Participants receive a certificate attesting
to the completion of 12 hours of instruction in the medical sciences. +
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~
I

Paganelli named Distinguished
Service Professor
harles V. Paganelli, Ph.D., professor of physiology at the University
at Buffalo, has been named a SU Y
Distinguished Service Professor.
A member of the UB faculty
since 1958, Paganelli has served as
interim chair of physiology since 1991,
a position he also held from 1980 to
1982 and in 1986. In addition, he was
associate chair of the department from
1976 to 1980 and from 1982 to 1991.
Starting in 1970, Paganelli was named
to several committees ofUB's Faculty of
Health Sciences (made up of all five of
the university's medical and health professions schools), in which capacity he
helped shape the role of those schools in
the university's mission.
An active researcher, throughout
his career Paganelli
has brought more
than $5.7 million in
awards to the university. His research has
taken him to locations that include the
Marshall Islands , the
Midway Islands ,
Alaska , and Hawaii.
He has presented lectures in Denmark ,
France , Switzerland, Italy , Israel , Taiwan, Korea , and japan , as well as
throughout the United State .
Paganelli has published more than
70 articles in professional journals and
is coeditor of the book Physiology Function in Special Environments.
His professional memberships include the American Physiological Society and the Undersea Medical ociety.
In 1995, he received the dean's award of
the School of Medicine and Biomedical
Sciences and the Student ational Medical Association Award. +

try , and Rehabilitation Medicine, and
the faculty of Social Sciences. Also participating is the Department of Veterans
Affairs through the VA Western ew
York Healthcare ystem.
"T his award by the Cummings Foundation will allow us to continue mapping the critical pathways by which
humans understand language ," says
Lockwood. "By studying the links between sound and emotion centers in the
brain , we may also be able to better
understand hearing loss and disorders
such as tinnitus or ringing in the ears,
which is associated with adverse psychological symptoms like depression , ~
anxiety, and insomnia."
a
In addition, the study will examine ~
auditory attention systerns that require ~
more complex processing of aural information and will analyze how the brain
handles language , including studies of
reading, grammar, and syntax. Such tests
have already proved useful in monitoring recovery from concussive brain injuries like the one suffered by former
Buffalo Sabres player Pat LaFontaine.
Using newly installed M Rl equipment and powerful computers in
Buffalo's VA medical center, the researchers will combine the MRI and
PET images to map the functions observed in the PET scans onto precise
locations in the body indicated by the
MRI images. Part of the funds provided
by the Cummings Foundation grant will
be used to upgrade the computer equipment and software to include this sophisticated image-fusion capability.
The james H. Cummings Foundation , located in Buffalo, was established
in 1962 through a bequest by james H.
Cummings, who was a prominent
manufacturer of pharmaceuticals with
operations in Buffalo and Toronto,
Ontario. The foundation has distributed more than $ 15 million in grants
to further medical science, research,
and education. +
~

UB medical school receives
$107,000 grant from James H.
Cummings Foundation
he University at Buffalo has received a $107,000 grant from the
james H. Cummings Foundation
of Buffalo to fund a pioneering
research project that will look at
how the brain transforms the
sounds we hear into information.
This three-year study will combine
images of brain activity formed using
positron emission tomography (PET)
scans with images of structures in the
brain acquired through magnetic resonance imaging (MRI) to create a unique
image that links neural activities to specific brain sites. Through the combined
images, researchers hope to gain new
insights into how sound relayed by the
auditory system are understood.
Directed by Alan Lockwood , M.D. ,
UB professor of neurology , the
multidisciplinary project will involve
the Departments of uclear Medicine
and eurology, Communicative Disorders and Sciences, Linguistics , Psychia-

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WITHERELL

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�HURWITZ &amp; RNE, P.C.
[ATTORNEYS

AT LAW

Put the best seat in the fwuse
myourgarage.

I

Maggie Wright med school
assistant dean,retires

SERYICI G
THE LEGAL

aggie Saxon Wright, assistant
dean for student affairs and director of minority affairs, retired
in August 1997. She had served
in the medical school's administration since 1981.
Wright oversaw the academic and
student affairs concerns of first- and
second-year medical students and administered the core basic science program, including medical electives, the
HLBI Summer Research Program, and
the ational Medical Fellowship Program. She also provided support
services to all medical student organizations and was advisor to the Minority
Undergraduate Pre-health Organization.
Active as director or advisor to many
local and national programs, Wright has
been honored both by medical educators
and by the community as the recipient of,
among other awards, the State of New
York's United University Professions
Excellence Award, the ational Medical
Association Award, and the NAACP
Medgar Evers Award. +

NEEDS OF THE
HEALTH Scm cEs

COMMU ITY
• Managed Care
• Purchase &amp; Sale of Practices
• Business &amp; Tax Planning
• HCFA Safe Harbor Regulations
and Physician Self-Referrals
• Contracts with Private
&amp; Public Entities

1997 Buick Riviera

• Employee Relations

Please contact
Robert P. Fine or
Lawrence M. Ross
at 716-849-8900

Riviera: the most sophisticated
personal luxury car Buick has
ever offered. It is designed to stir
the spirit and excite the soul.
We at Paul Batt Buick are proud
to serve the people of Buffalo and
its surrounding communities. For
the last 43 years, we have offered
the lowest prices possible, along
with the very best in service.
We value the professional and
the hard working labor force in our
community and will continue our
efforts to maintain their loyalty.
When you enter our showroom
you will find helpful people, not
pressure-so when you think of
Buick sales and service, we know
you'll think of us!
Joseph R. Pera
Paul V. Batt, Jr.

1300 Liberty Building

1717 Walden Ave. , Buffalo, NY

Counseling
• Fringe Benefit Programs
• Representation Before
Government Agencies on
Audit &amp; Business Issues
• Facility Finance
and Construction
• Credentialing
and By-Laws
• Hospital/Medical Staff Issues

'ldut'!Jall7Jlliti

Buffalo,

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ew York

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Key issues include relations between
the medical school and the local medical community, relations between the
BY
ANDREW
DANZO
school and the university as a whole,
and changes in patterns of medical practice and teaching. Underlying it all are
the economic factors driving much of
hey don't do it for the glory-the Dean's Advisory Council is the change-the decline of government
a relatively unheralded group that prefers to meet outside the support, the rise of managed care. To
preserve an atmosphere in which memspotlight. They certainly don't do it for the money-members bers speak freely, Wright hesitates to
relate details of Advisory Council dispay their own way, even if they must take a cross-country cussions, but he will say that recent
sessions have touched on such subjects
flight to participate.
as the importance to the school of its
What they do for the chool of Medi- the council after having spent 24 years volunteer faculty and the planned mergcine and Biomedical Sciences, however, as chair of orthopedic surgery at UB.
ers among institutions in Buffalo's teachis becoming increasingly valuable. With
Bradley Aust, M.D., founding chair ing hospital consortium.
a roster of senior alumni and faculty of the Department of Surgery at the
Some Advisory Council members
members, the Dean's Advisory Council University of Texas at San Antonio have already been through similar issues
is helping the school position itself to and a member of the
elsewhere. "They can
maintain leadership in medical educa- UB Class of 1949,
provide us with some
DEAN 'S ADVISORY COUNCIL
tion, biomedical research , and health- agrees: "We're happy
of the scenarios and
some of the things we
care policy during a period of profound to try and be supJ. Bradley Aust, M.D.
national change.
need to pay allention
Charles D. Bauer, M.D.
portive in giving adMichael E. Cohen, M.D.
"The Dean's Advisory Council is a vice. One of the
to from the perspecS.
Max
Doubrava,
M
.D.
tive of the medical
forum to put forth provocative, poten- advantages of outJock C. Fisher, M.D.
schoo I," Wright says.
tially controversial ideas; to get a reac- side participation is
James R. Konski Jr., M.D.
"Experience is a wontion from individuals both inside and that we're at other
Jerome P. Kossirer, M.D.
outside this community," says interim universities and
derful teacher. "
(Con sultant )
dean and vice president for clinical af- medical schools:
In February of
Harry l. Metcalf, M.D.
fairs John R. Wright, M.D. "I articulate There are some
this
year, the group
Eugene R. Mindell, M.D.
current issues facing the school, warts generic problems
met
in
Boston at the
Richard B. Norins, M.D.
and all. I don't think I hold anything that cut across uniHoward Hughes
Margaret W. Poroski, M.D.
back ... and the Advisory Council is not versity boundaries,
Medical Institute,
Dorothy C. Rosinski-Gregory, M.D.
reticent about providing advice."
and we can tell [the
where the Advisory
Albert C. Rekote, M.D.
Established two years ago by former dean] about our
Robert N. Schnitzler, M.D.
Council's honorary
George W. Thorn, M.D.
dean John P. a ugh ton, M.D., the coun- problems and how
chair , UB Class
(I lonon11y Clw ir)
cil represents a broad range of experi- we solve them. "
of 1929 member
Philip B. Wels, M.D.
ence. Members from the Buffalo area
George W. Thorn,
Wright sees the
Franklin
Zeplowitz,
M.D.
include faculty who are heavily involved council,
M.D ., has served as
which
in the UB medical school and alumni meets three times a
research director.
who are active in the local medical com- year, as a combina"He talked about his
munity. Other council members, many tion of expert panel and sounding board life," recalls Mindel!. "He gave us
of whom hold distinguished academic to help the school grow stronger in an some suggestions about how our
and research positions, are scallered unpredictable but rapidly evolving en- school can attract outstanding facaround the country.
vironment. "It's a given that we're not ulty and how to pursue funding for
"We would like to help the UB School going to stand still," he adds. "We're activities we're interested in. "
of Medicine to move ahead," says Eu- going to have to think of different ways
ext February council members will
gene R. Mindel!, M.D., who serves on of doing things."
travel to San Diego, where they will be

Dean's Advisory Council

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hosted by jack C. Fisher, M.D., a UB
Class of 1962 member who is among the
group's most active participants. A noted
professor of surgery at the University of
California at San Diego and former head
of that school's Division of Plastic and
Reconstructive Surgery, Fisher hopes to
provide insight for developing strategies in Buffalo.
"There are contrasts to what's happening in Buffalo with what I've experienced here in California," Fisher says.
''I'm planning to give [council members] the opportunity to meet with some
of the administration from our medical
chool and medical center to discuss
how managed care has inOuenced our
own graduate and undergraduate medical education. It's been hard. "
Fisher, who devotes at least several
days a year to Advisory Council meetings
and preparation , sees it as a way
of giving back to his alma mater. "Basically, I'm a graduate, and Buffalo is my
home. I was honored to be asked, and I
find it interesting." +
Andrew Danzo , a Buffalo -based freelan ce
writer, is a frcc1uent contributor to Buffalo

Phys ician .

INFINITI
AUTO PLACE
INFINITI

8129 MAIN ST.,
WILLIAMSVILLE
633-9585

East of Transit Rd.,
Near Eastern Hills Mall

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UB first to complete Women's
Health Initiative enrollment
he University at Buffalo is the first
of 40 sites in the nation to meet all
its recruitment goals for the $625
million Women's Health Initiative (WHI), the largest clinical trial
ever undertaken in the U.S.
UB's Department of Social and Preventive Medicine was selected in
1993 to be one of the initiative's 16
Vanguard Clinical Centers. These sites
established the study's design and developed the operating procedures for
the remaining centers. A total of 4,000
women in Western ew York have
volunteered to take part in this landmark study.
The WHI's goal is to arrive at definitive answers concerning the relationship of hormone-replacement therapy
and various aspects of diet on women's
long-term health. A third aspect of the
project, the observational study, involves tracking women over the 12year study period to determine lifestyle
habits that are beneficial or harmful.
Specifically, the study will seek to
determine risk factors for heart disease,

the largest killer of women; breast, colon,
and endometrial cancers; osteoporosis;
and Alzheimer's disease. The WHI eventually will involve 163,000 women nationally between the ages of 50 and 79.
Karen Falkner, Ph.D., recruitment
director for UB's Vanguard Clinical
Center, says that being the first to reach
its recruitment goals is a significant
accomplishment for UB and a testament to the generosity and insight of
the women in Western New York.
"These volunteers are willing to devote
a part of their lives for the next decade to
helping improve the health of women for
generations to come," she says. "They are
part of a history-making adventure."
The university's share of the grant
forthe WHI study is $11 million spread
over l2 years. Co-principal investigators on the trial are Maurizio Trevisan,
M.D., professor and chair of the UB
Department of Social and Preventive
Medicine, andjean Wactawski-Wende,
Ph .D. , UB assistant professor of gynecology and obstetrics.
The university's recruitment success
in this clinical trial will help make it a
prime site for future investigations,
Falkner says. +

When the engineers at lnfiniti set out
to create the new flagship Q45,
they didn't ask each
other, "What does a
luxury car owner desire
most in a luxury car?"
They asked the luxury car
owners themselves. In countless interviews, Infiniti asked
questions like, "What catches your eye?", "What tickles your
fancy?" and "What makes your heart pound?" The result?
Styling that's the perfect blend of elegance and sportiness.

Physician

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Aword from the director of development
BY

LINDA

J

.

CORDER.

PH

0

..

C

hanks to many generous medical graduates who celebrated a
class reunion this past spring, the Medical School Reunion
Giving Program for 1997 received a prestigious award from
the SU Y Council on Advancement and Development. I had
the felicitous responsibility of accepting this] udges' Citation on
behalf of the school during the annual SU Y/CUAD Conference,
held in Corning,

Y, this pastjune.

The entry of the School of Medicine
and Biomedical ciences was one of 113
submitted for evaluation of excellence
and improvement by a panel of experts.
Of the programs or publications evaluated, there were eight recognized as
"Best of Category" and 11 that received
a "judges' Citation." Our program received a judges' Citation.
Last fall , we analyzed the Medical chool Reunion Giving Program by the results it had obtained
over the previous six years. The
amount of reunion gifts given to
the school during that time period
wa slightly more than $575,000an average of 92,500 a year, or
under $10,000 per class, per year.
With the assistance of former
dean Dr. john aughton, we recruited reunion gift cochairs for
most of the classes celebrating reunions. As far as I have been able to
a certain, this year was the first in which
most class reunion chairs had a cochair
to assist with their class gifts. We extended the definition of "reunion class"
to include all living alumni who graduated in years ending in "2" and "7." This
added four reunion classes within the
"jubilee Emeritus" group. Two-the
55th and 60th year classes-took active
roles in this year's reunion celebrations.

®

We encouraged class members to
make gifts to any fund that would benefit the School of Medicine and Biomedical Sciences. In the past, class
members were asked to contribute to a
specific reunion account, for a purpose
decided by someone else.
We also included a one-page survey
in the initial mailing. This provided
each class member with an opportunity

to update the information on file in our
office and that of the Medical Alumni
Association, to rate their perceptions on
various aspects of medical practice, and
to s hare per onal information with their
classmates. (A t press time, we are still
working on the "class booklets" based
on these survey . They will be finalized
and mailed to each person who made a
reunion gift, ca me to reunion weekend,

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or took the time to complete and return
the survey even if they could not come
to the reunion or did not make a
reunion gift.) These four program
enhancements likely resulted in the
increased reunion giving upon which
the award was based.
Several people made gifts based on
Dr. aughton's suggestion of $100 for
each year since graduation, and many
additional individuals gave contributions of 1,000 or more that will result
in their recognition as members of the
james Platt White Society for 1997. Overall, reunion class members committed
more than $136,000 to the school, with
a participation rate of 33 percent. This
amount is more than double the total of
reunion gifts made in 1996 and it surpasses the average of the previous six
years by $44,000-that's an increase of
48 percent!! Twelve additional reunion class members made pledges
of unspecified amounts. Depending on the magnitude of these gifts,
the percentage of increase may be
even more significant.
The reunion class with the highest
gift total-more than $30,000-was
the Class of 1942. This successful
effort was led by Richard Ament,
who established a Charitable Remainder Unitrust in honor of his
55th reunion . He designated the
remainder amount for the Department
of Anesthesiology.
Two classes shared honors for the
highest percentage of participation: More
than half-58 percent--of the living class
members of the Class of 1937 and the
Class of 1947 made a reunion contribution. Above 40 percent were the Classes
ofl967 and 1952, with 42 percent and 41
percent participation, respectively.

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How does this compare with other
academic medical centers? From one
perspective, not very well. My evidence
is anecdotal , primarily from UB graduates who completed their residencies
elsewhere and receive anoth e r
institution's alumni publications. A UB
alumnus in Arizona told me of a friend
from residency whose medical class
made reunion gifts totaling more than a
million dollars. nearly twice as much as
all of our classes combined, over a sixyear period' However, that was a private
institution, with a development program that is more than 100 years old. A
California surgery professor, also a B
alumnus , described a multimillion dollar annual philanthropic program at

his university, of which the reunion
gifts made up a significant percentage.
Like UB , this is a publicly assisted institution , but with a much shorter history
than UB's 150+ years. Yet that medical
school was established with the knowledge of the need for-and expectation
of-significant private contributions.
So, what is the "right" perspective by
which to assess our program7 For now,
l come down on the side of the panel of
judges for the SU Y/CUAD awards. We
provide our own standard of comparison. In this first year of increased efforts
and generosity, the classes celebrating
reunions in 1997 made significant
progress over previous results . Our
improvement earned us a citation of merit.

Our efforts this year will provide
benchmarks for future years of this program. Over time, reunion gifts have the
potential to transform the academic and
clinical opportunities currently available
to UB's medical students. Over time, more
classmates will want to participate and to
contribute at levels that will bring them
increased personal recognition and enhance
their alma mater in significant ways.
Who knows? Within the next few
years, the certificate earned this past
spring may have a companion piecean award of excellence for best program
in the development category! +
Liuda j. Cordc1 is assist aut dcau aud
dirccto1 of dcvclopmcuL

Medical School Reunion Giving Program 1997
Class
Year

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in Class

Number
Who
Gave

Gift
Amount

Number
Who
Pledged

Pledge
Amount

Total Number
of Gifts
and Pledges

Total Dollar
Amount

1937
'42
'47

12
32
48

6
9
26

$6,331
1,910
17,684

1
2
2

(l nspecijied)

$28,625
550

7
11
28

$6,331
30,535
18,234

58%
34
58

'52
'57

49
56

19
17

13,735
3,400

1
4

1,650
700

20
21

15,385
4,100

41
38

'62
'67

58
95

20
31

11,343
9,830

2
9

8,650
1,645

22
40

19,993
11,475

38
42

'72

121

26

9,073

7

3,817

33

12,890

27

'77

125

28

5,830

10

1 245

38

7,075

30

'82

121

26

3,950

7

660

33

4,610

27

'87

111

21

3,172

12

1,900

33

5,072

30

'92

119

19

675

7

295

26

970

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Class
Participation
Percentage

(I inspecified)

(2 Cnspecifled)

(2 Cnspecijied)
(2 lnspecifled)

(2 { nspeci}ied)
(I lnspecifled)
(I lnspecifled)
(I Cmpecijied)

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,ar.l"'mllllll':'l
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Mandeville's suggested transition-tointerview statement isn't terribly different from the one Dr. Manyon asked us to
use in our preceptors' clinics: "So, what
brings you to see the doctor today? "
While Mandeville certainly doesn't give
the patient room to expound upon his
BY JUDITH TOSKI . CLASS OF 2 0 0 0
condition (Dr. Manyon would reprimand him for not using an open-ended
question),
it is noble that Mandeville
tis the year 1300, and you are a provincial lord in France. You have
and his contemporaries would even
been coughing for days, ever since you somehow stumbled into speak to patients. There was little
patient-doctor interaction in the earlier,
some bad air while hunting your grounds. You send for the local pre-university Middle Ages. Prior to the
physician. Along with your messenger you send a flask of your rise of the university system, physicians
would instead receive the patient's
urine, a you expect the doctor to have formulated an opinion urine and make a diagnosis from it alone,
without ever seeing or speaking to
regarding your prognosis before he arrives at your bedside.
the patient.
In medieval European iconography, versibly altered by the innovations of
Other aspects of doctor-patient inthe urine flask was the universal
science and technology, there is one teraction have also been retained
symbol of medicine. It implied
element of medical care that has not through the ages. The idea that the
great understanding, much like
changed quite as drastically: the art patient's trust in the physician is parathe long white coat suggests
of doctor-patient interaction.
mount is a concept that has been alive
Henry de Mandeville, a physi- in some form since antiquity, when
the medical expertise of A~~~!!~~
today's attending phycian and surgeon who Greek believers sought healing from
sician. While the symwrote around 1315, de- the god Aesculapias. During the 14th
bot has changed, the
scribed a proper method century, Arabic texts from the early
connotation
has
ofquestioningapatient- Middle Ages came into vogue in
not. What imparted
onewhich,inmanyways, Europe-including one by Qusta ibn
power to the repremirrors the paradigm my Luqa, a writer on psychosomatic medisentation, both in the
class was taught in cine. This treatise explained that magic
Middle Ages and today, is
Clinical Practice of spells and incantations cure illnesses
the patient's belief that
Medicine during our because patients want to believe in
"this doctor is a person
first year at UB. In them , and th e mind controls the body
who can heal me. " The
a descrip- to effect the remedy. The medical intion of the novators of 14th-century Europe took
remedies of both eras refleet the scientific underp r o p e r this concep t one step further, indicatstanding of the time, and thus
protocol for ing that physicians have the power to
would be completely differentbringing in a cure because patients accept that they
the provincial doctor would have
consultant on have such power. In the absence of
applied poultices of mustard and
an ongoing case, extensive pharmacopoeia or advanced
other materia medica to the lord's
M o n d e vi I I e surgical techniques , the patient's beche t, while today's primary-care
specified the lief in the ability of the physician to
phy ician would most likely
language that heal was essentially the only tool that
auscultate his lungs and chashould be used with the doctors had available to them. Today,
tise the lord for keeping up a
patient. He recom- in spite of improvements in medical
three-pack-a-day smoking habit. AI- mended that the patient be interviewed, technology and the wide range of drugs
though aspects of the treatment and first saying: "Sir, I hope it will not offend available to physicians to help ameliophysical examination have been irre- you if I ask when your illness began?" rate disease, not every illness has been

Doctor-Patient Interaction: Lessons
from the Late Middle Ages

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il
Medicine has changed because the
world around it has. Advances in scientific thought and innovations in technology have transformed how care is
delivered in so many ways that it is
inconceivable to us moderns that anything could have remained the same
about it. And yet, some similarities do
exist between our culture of physicianpatient interactions and that of the
Middle Ages. The desire of the patient to
have faith in the doctor and his cures
has not been modified all that much,
and the necessity of open communication between physician and patient is
a concept that even today is being
taught and reinforced in UB's medical
curriculum-to our advantage as future
physicians, and to the benefit of our
current and future patients. +
Details on medieval medical practices taken

cured. In such cases we have the same
tool available to us that Henry de
Mandeville and h is contemporaries
had: that is , our patient's belief that we
will try to save him if it is at all within
our power to do so. This is a skill that
transcends wearing a white coat or

schlepping a pager around. My mentor, Dr. julian Ambrus , taught me that
trust must be earned and reinforced in
each encounter with every patient. A
physician can only obtain trust when
he treats the patients with the honor
he would accord a superior.

from McVaugh, Michael R. "Bedside Manners
in the Middle Ages." Bulletin of the History of

Medicine, val. 71, no. 2, johns Hopkins UP,
Baltimore, MD.
judi tit Toshi It as a B.A. in history of medicine from

Thcjoltns Hopllins University.

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--~

�Tone Johnson J[ '75: Alum earns
belated decoration for bravery

"When 1 got back, the very people I
thought 1 was defending didn't like me
very well. And that had nothing to do
with being black-it was any soldier
who was in Vietnam."
Johnson said he dealt with the adjustment by disappearing into the colBY
VIVIENNE
HEINES
lege environment. After graduating from
Grambling College, earning his M.D.
from UB, and completing his residency,
uring a three-day period in 1965, a 19-year-old U.S. Army he served two more years in the military
private named Tonejohnson found himself in a Vietnam jungle, and two years with the U .. Public Health
Service before entering civilian life as a
surrounded by dead or dying companions and hostile orth family practitioner.
ow married and the father of five,
Vietnamese regulars.
Johnson runs his own practice and has
that it is not uncommon for soldiers to recently opened two drug treatment
As the American came under inreceive awards many years after they centers. As a lieutenant colonel in the
creasingly heavy mortar fire, they ran
out of ammunition and nearly lost any
served. Congress also expanded the U.S. Army Reserve Medical Corps, he
eligibility
hope of surviving. Most didn't. Of the 35
runs a comrules for commen in his unit,Johnson was one of five
bat medical
""IT WOULD HAVE BEEN EASY TO JUST
bat veterans
who lived through what became one of
training proGIVE UP. BUT ABOVE ALL. I BELIEVED
the worst battles of the Vietnam Warto
receive
gram
to teach
THAT MY FELLOW TROOPS WERE GOING TO
decorations
la Drang Valley, ovember 14- 17, 1965.
ordinary
solCOME . AND THEY DID .""
in 1996.
"We ran out of ammunition at about
diers prin one in the morning. We were only saved
Johnson
ciples of first
by what we fondly called 'Puff the Magic
attributes the award to the research of war aid and emergency medical care in the
Dragon' [rapid-firing gun hip aircraft]
correspondentJoseph L. Galloway, who field of combat.
and the Air Force," John on recalled.
described the horrors of Ia Drang in We
ln the la Drang Valley battle,Johnson
An American plane arrived, fired nearly
Were Soldiers Once ... and Young, the was wounded in several places. An exatop the soldiers, and dropped napalm
1992 book he coauthored with retired plosion gave him a concussion and
around them.
Lt. Gen. Harold G. Moore .
knocked him unconscious. He woke up
"That really cleared them out. l was
Johnson , now a family practice doc- in the middle of the shooting to find a
close enough that 1 could feel the heat
tor in Corpus Christi, aid the award is
orth Vietnamese soldier sitting on his
significant to him.
from the names, but it wasn't close
chest and eating his C-rations, he once
enough to actually burn me," Johnson
"lt means my country cares. Above told an interviewer from the ueces
all things, it means my country cares," Valley Medical Society newsletter.
said. "Frankly, I was glad they did [drop
he said.
the napalm], because a little longer and
"This ticked me off," he said.
we would have been goners."
Like many Vietnam veterans ,
WhenJohnson moved, he startled the
In ovcmber 1996, the 51-year-old John on returned to an American pub- soldier, who jumped up and shot him in
Johnson received the Bronze Star for
lic that was neither appreciative nor the armpit before being killed in the
meritorious achievement in recognition
accepting of the horrors he had experi- intense fire that ensued. Johnson also
of his efforts to repulse the enemy durenced. Because of his race, he felt the suffered injuries to the face and knee.
ing the bloody battle at la Drang Valley.
adjustment even more keen!)'·
The scar on his face is barely visible
The award was pre en ted at a ce remony
"As a black person in the war, it was today, but shrapnel wounds cost him
in the ational Guard Armory in Corkind of tortuous. At home , we were the peripheral vision in his right eye.
pus Chri ti, T .
undergoing racial conOict. Then , in the
"As I took care of the other soldiers
war, we were undergoing that kind of during the night, a few of them said,
A spokeswoman for the Army Personnel Agency, in Alexandria, VA, said
armed conOict," Johnson recalled . 'Let's just give up. We're all worn out,

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�we don 't ha\c an\ thing. ' The) had been
wounded , and some were blccchng quite
badl) and were ma) be a liulc bit delirious," johnson recalled .
johnson got through the night b)
maimaining his faith in God and in his
fellow soldiers.
'"A ll I could thmk was, 'The} 'll be
here. ' And through the night, as we prayed
about it, I knC\\ the) 'cl be here . It would
ha\ e been caS) to just give up . But aboYe
all, I believed that 111) fcllO\\ troops \\ere
going to come. And the) did. "
johnson said he has goucn past his
nightmares about the \\ar, but it has
changed him in other ways.
" People ~a) , ''r ou 're so calm.' I sa), 'If
you\e been through hell once, it's easy

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to li-,:c in America .' Lillie things
don't bother me nO\\. "
Reprinted b) pctnih&gt;ionfmmtlicCotpus CI111Sli (Tnm) Caller- Times. +

~ 1998 SCD plans

I

Plans for the 1998 Reunion Weekend and Spring Clinical Day (April25, 1998) are already well under
way. This year's program is chaired by Dr. John Bodkin. The following reunion chairs held their
organizational meeting September 11 : the 50th Year Class of '48, Dr. Daniel Fahey and Dr. Harold
Graff; the Class of '53, Dr. Michael Sullivan; the Class of '58, Dr. Alfred Stein and Dr. Michael Genco;
the Class of '63, Dr. Anthony M. Foti; the Class of '68, Dr. Robert Milch and Dr. Thomas Cumbo; the
25th Year Class of '73, Dr. Michael Sansone and Dr. Arthur Mruczek; the Class of '78, Dr. David
Marchetti; the Class of '83, Dr. Richard Collins; the Class of '88, Drs. Andrew and Helen Cappuccino;
and the 5th Year Class of '93, Dr. Michael Aronica.

Physician

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daring surgery. The idea was to
increase the collateral circula-

bany,

Pensacola, FL, writes: "There's

tion to the ischemic cardiac

from chair of Dept. of ObGyn,

nothing like a sentimental enco-

muscle. After a couple of hours

Albany Medical Center, after 16

mium to stir fond memories. So

of holding retractors, one be-

years.

iL was when I read of the death of

came lax. Dr. Stewart always had

and chair the board of Maternal

JOSEPH

H.

MELANT '43 ,

of

M Y R ON G O R DO N '48 ,

of AI-

the same poignant question:

Infant etwork of the Capital Re-

4, 1996) in Buffalo Physician.

'Doctor, are you holding those

gion, and chair the Committee on

Fifty-five years ago I had the

retractors, or are those retrac-

Medical Schools and Graduate

good fortune to assist this gifted

tors holding you?' He was the

Medical Education of MSS Y.

man in the first open-heart sur-

embodiment of integrity and the

Looking forward to 50th next year.

gery performed in Buffalo, at

sui generis of his time. "

Skip Zola, Bill Bloom , and Dan

a senior in medica l school, thus
I had the honor of being his

fourth assistant (there wasn't
room at the table for any more!).
It was a period when opening

the pericardia! sac and dusting
some talcum powder into it was

SAMUE L

CASSARA

Rochester,

'44 ,

of

versity of California at Irvine.

1

ow teach, office practice,

Dr. John D. Stewart (September

Meyer Memorial Hospital. I was

(addiction medicine) at the Uni-

Y, writes: "Stepped down

9

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FOGAN

' 65 ,

of

Valencia, CA, writes: "!took full
early retirement from the Southern California Permanente Medical Group on July 31, 1997. I
spent my entire practice career
at the Kaiser Permanente Medical Center in Panorama City,

Miller were here in Albany in April

CA, beginning in july 1971. My

for our son Seta's bar mitzvah. "

last 16 years I served as chief of

Y, writes that he

the

eurology Department. I ex-

retired May 30, 1997, after 48

MAX A . SCHNE I DER '49 ,

years of pediatric practice, at the

Orange, CA, has been elected

pect to pursue my many inter-

chair of the board of the

ests happily and full time."

age of 78 years.

ext? "I will

of
a-

write an autobiography of my

tiona! Council on Alcoholism

life and times. "

and Drug Dependence. He is a

IRVING S . KOLIN '65 ,

recently

appeared on Channel9 in Miami,

clinical professor of psychiatry

If you come loolting for a car,
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HOWEVER, there's little chance you'llleave tl1at way. BECAUSE at tl1e Land

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•

I

FL, to discuss psychological
trauma in victims of child kid-

the Southern California Kaiser

publications are Sexual Investi-

Permanente Health Care Pro-

gation (NYU Press, 1996); Sex,

who joins jacqueline (7), Alex
(5), and Eric (3). Marc is direc-

napping, and ADHD and the
Ritalin controversy.

gram. The department has a staff

Love, and Friendship (Rodop,
1997) ; The Philosophy of Sex

thalmology at Florida Health

( Rowman, 1997); and The Pili-

Care Plans in Daytona Beach, FL.

JOHN E . SHIELDS '68, of
Delhi, Y, writes that his son john

JOHN E . KNIPP '72 , of
Washingtonville, Y, is presi-

losoph) of Sex and Love (Paragon
House, 1997).

JENNIFER L. CADIZ '87 writes:

M. Shields has ajD/MBA degree

dent and chief of staff of the

with honors, and Gregory P.

Cornwall Hospital, Cornwall,

hields is a freshman at Univer-

Y, and president-elect of the

of 80 MDs and ER As.

sity of Arizona. He adds that he is

Orange County Medical Soci-

at Russell Sage College in Albany.

ety, Orange County, Y. He is in
the private practice of internal

1

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DONALD H . MARCUS '71 , of
Sepulveda, CA, has been appointed chief of anesthesiology
at the Kaiser Foundation Hospital in Los Angeles. The L.A. Hospital is the tertiary hospital for

WNY's

medicine and gastroenterology.
ALAN S OBLE '72 (M.A. Pharmacology), of ew Orleans, LA,
writes: "l have recently been
promoted to full professor
( 1990) and to research professor (1994). Among my latest

tor of the Department of Oph-

''I've moved to Harrisburg, PA,

1

9

8

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to begin life as a civilian. I'll be
practicing with one of the local

KEVIN S . F ERENTZ '83 , of

hematology/oncology groups."

the Pikesville section ofBaltimore,
MD, has been installed as the

LA URA POST '87, of Saipan,

49th president of the Maryland

has been appointed chair of the

Academy of Family Physicians
(MAFP).

Department of Psyc hiatry at
Commonwealth Health Center,
in Saipan. Her first book, Back-

MARC J . KOBLICK '84. of
Ormond Beach, FL, and his wife,
Helene, announce the birth of

stage Pass: Interviews with Women
in Music, has just been published
by

ew Victoria Publishers.

their fourth c hild, Reid Jayson ,

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····························· · ···· ·· ·····

.
I

THE ULTIMATE DRIVING MACHINE.

JOHN AKER '88 ,

oflndianapo-

ANTH ONY

R .

RICOTTONE

lis, I . writes: "I finally finished

'91 , of Cheektowaga.

my plastic surgcl) fellowship at

" "vly wife, Deborah, and I arc

YU, and am now in private
practice

in

Indianapolis.

) . \Hites:

pleased to announce the birth of
our daughter. Marisa. Our son

Kathleen and I were recently

Dommie recent!) turned 2. I ha\ e

blessed by our second child,

recently joined KeY in Barloc, Rt-

Zachery Alexander."

charJ Gilbcrt,andJohn Gri~wold
at Buffalo Medical Group tn the
of

DEBRA M . OMIATEK '89 ,

Lewiston,

practice of urolog\."

Y, is celebrating her

first year in private solo prac-

CAROL ANN KILLIAN '94

ti ce. She is president of the

THOMAS M . BURNETTE '94 ,

iagara County Chapter of Family Practice (AArP).

of Sleep; Hollo"',

9

9

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and GALE
of Baltimore,

PETEF&lt;BLOOM '90

emergenc\

111

MD, write that Peter has recently

Westchester Count} ,

ni-

Ann has accepted a JOb as an rD

versity of Maryland; he i working on research on infectious

County Medical Center and Tom

dysentery at the Center for Vac-

has begun working as an inter-

111

the \ Vestchcstcr

cine Development in Baltimore.

nist in the Mount Kisco Medtcal

Gale just received her master's in

Group. The; keep in close con-

public health from The Johns

tact with Barb Kearnq, \\ ho

Hopkins School of Hygiene and

married Paul Stcfantck tn '&gt;ep-

Johns Hopkins in a CD -funded

is finishmg her patholog\ resi-

sexuall y transmitted diseases.
Gale spent this past spring in

tiful bah) girl named

South Africa, where she consulted

rebruar) 1997.

health services.

atalt e

low to mid 20's; leases
starting at $299 per month.

MIKE J . PELECHAGY JR . ' 94 ,

of Orchard Park,

) , \Hites:

* According to the Insurance

"\\ c've .Just accepted a fellowship
position at Roswell Park 111 hema-

GULATI '92 announce

the birth

tology/oncology , starting Juh l ,

of their son Suneel S. Ram on

1997. Also, '' e had another bah)

Feb. 21 , 1997. Ragh u has joined

girl, OliYia Paige. We're glad to he

Kenmore Family Medicine, a

back in the Buffalo area. r or those

new group practice in Kenmore,

on the Internet, look up m) nc\\

Y. Neeva is completing her rP

[-mail address either at ..,,,Itch-

niversity at

board or 411.

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and

RAGHU RAM '90

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TAKE TWO ...

reside in Tonawanda while Barb

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next issue. -Eel.

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Orchard Park, NY 14127

Autumn

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                    <text>State University of New York at Buffalo School of Medicine and Biomedical Sciences, Winter 1998

Out with the Rote,
-UNDERGRADUATE CURRICULUM RESTRUCTURED TO INCLUDE PROBLEM-BASED LEARNING

in with the ew

�BUFFALO PHYSICIAN

Volume 32, Number I
ASSOCIATE VICE
PRESIDENT FOR
UNIVERSITY SERVICES

Dr. Carole Smith Petro
DIRECTOR OF
PUBLICATIONS

Kathryn A. Sawner
EDITOR

Stephanie A. Lnger
ART DIRECTOR/DESIGNER

Alanj. Kegler
PRODUCTION MANAGER
Ann Raszmann Brown
STATE UNIVERSITY OF
NEW YORK AT BUFFALO
SCHOOL OF MEDICINE
AND BIOMEDICAL
SCIENCES

Dr john Wnght, lntcrun Dean and
Vice PreSident for Clinical Affairs
EDITORIAL BOARD
Dr. Bertram Portm, Chait

Dr. Manm Brecher
Dr. Harold Brody
Dr. Lmda j. Corder
Dr. Alan j. Dnnnan
Dr. james Kanski
Dr. Barbara MaJerom
Dr. Elizabeth Olmsted
Dr. Charles Paganelli
Dr. Stephen Spaulding
Dr. Bradley T Truax
Roy Vongtama
Dr. Franklin Zeplowilz
TEACHING HOSPITALS AND
LIAISONS

The Buffalo General Hospital
Michael Shaw
The Children's Hospital of Buffalo
Erie County Medical Center
Mercy Health System
Millard Fillmore Health System
Franll Sara
Niagara Falls Memonal Medical
Center
Roswell Park Cancer lnsl!lule
Sisters of Charity Hospital
Dennis McCarthy
Veterans Affairs Western New York
Healthcare System
©The Stale University of New York
al Buffalo

Buffalo Physician is published
quarterly by the Stale Universny of
ew York al Buffalo School of
Medicme and Biomedical Sciences
and the Office of Publications. It is
sent, free of charge, to alumni,
faculty, students, residents, and
friends. The staff reserves the nght
to edit all copy and submissiOns
accepted for publication.

Dear Alumni and Friends,
Nov.

THAT 1997 HAS ENDED AND WE BEGIN to contemplate what made this year
particularly interesting and challenging, several things come to mind. The rapid
changes in the local health-care delivery system represent perhaps the most
important of these issues, not only because they affect our primary mission-the
education of future physicians-but also because of how the medical school
enterprise is currently financed. The state budget provides only 13 tol4 percent
of our annual expenditures, matched by approximately the same percentage from
extramural-sponsored research programs. Since hospital support, which also
includes the residents' salaries, accounts for approximately 23 percent of total
expenditures and the practice plan, an additional 41 percent, over 60 percent of
our funding is derived through the health-care delivery system. Changes in the financing of this system,
together with its overall configuration, are therefore of vital interest to us. As we begin 1998, the merger
of Buffalo General, Children's and Millard Fillmore hospitals is poised to occur, yet the consequences
of the merger (for us and others) are far from clear. The Catholic system is undergoing similar merger
discussions, while Erie County Medical Center and Roswell Park are in the process of determining their
respective roles within this rapidly changing environment.
As if this were not enough, we are actively engaged in reengineering the residency training
programs in response to the well-publicized Medicare Demonstration Project, which calls for a 20
percent reduction in resident training positions over the next five years. This process has been
complicated by the fact that most of our programs are dispersed throughout multiple hospital sites and
in order to maintain quality (not to mention "accredited") programs, any significant downsizing will
undoubtedly require program consolidation to fewer sites. The latter is further complicated by the
financial implications to the participating hospitals and the availability of specialized training
opportunities for specific program needs. The planning process is moving ahead, but many of the very
difficult decisions are yet to come.
Against this background, we must continue to develop innovative educational programs for our
students, maintain the basic relevance of our curriculum and prepare our students for whatever future
medical practice demands. (Fortunately, our students are an adaptable lot and probably better able to
manage these changes than some of us older folks.) A number of exciting programs are under
development to achieve these goals, some of which are presented in this issue of the Buffalo Physician.
Finally, with 1997 having come to a close (and my first year as interim dean), I want to take this
opportunity to wish each and every one of you a happy and fulfilling New Year!

John R. Wright, MD
Interim Dean, School of Medicine and Biomedical Sciences
Interim Vice President for Clinical Affairs

Dear Fellow Alumni,
Change is definitely the key word and it is currently rapid and aggressive. With
winter here, I would advise those physicians who ordinarily choose to hibernate,
to forego the temptation and stay alert. If not, they could awake to a considerably
different medical environment. The steady advancement and influence of managed care, combined with the merging of health systems and HMOs/insurance
companies, is creating a sense of stress. With those thoughts in mind, it is
refreshing that I have had the opportunity to reflect on the future of medicine
through the eyes and perception of members of the younger generation. First-year
student Ryan, who is my mentor partner, and my son jerry, a PGYI resident,
visualize their medical careers with joy, anticipation and determination. How nice
it would be if that vision could be projected to a number of my colleagues. Attitude is obviously the key
to handling the stresses of change.
Plans for the 1998 reunion weekend and Spring Clinical Day, April25, 1998, are well under way.
Dr. John Bodkin is arranging a program on aging, and the reunion chairs are making arrangements and
contacting classmates. An article in the autumn 1997 issue of the Buffalo Physician noted that the
reunion class commitments in 1997 were increased by 48 percent. Let us keep up the momentum. It
is badly needed in this era of rapid decline in state support.
Please plan on joining us in celebrating and supporting your excellent medical school.

~B.c:~.M~~

President, Medical Alumni Association

�VOL U ME

32 ,

NUMBER

1

WINTER

Out with the Rote,
in with the New

2

CURRICULUM

12

Medical Student
Exchange to Bosnia

18

EXPERIENCE BRINGS NEW

RESTRUCTURED TO

PERSPECTIVE TO U B

INCLUDE PROBLEM-

STUDENTS

BASED LEARNING

by Michael Beebe

1998

Communication
Skills lor Tom~rrow's
Physicians
NEW PROJECT TO MORE
FORMALLY INTEGRATE

TEACHING OF EFFECTIVE

by S. A. Unger

COMMUNICATION SKILL S

photos by Frank Cesario

by S. A. Unger

Heidi DeBlock, MD,
PARLAYS HER FASCINA-

TION WITH SPACE INTO

REGULAR STINT AT
HOUSTON'S LB.J SPACE

CENTER

New Computer Lab

by Nicole Peradotto

NEW "E-TECH" COMPUTING LAB GIVES
STUDENTS ACCESS

3

Medical School
DAVID K.

MILLER ,

MD,

"A GIANT IN HIS FIELD,"

TO STATE-OF-THE ART
DIES

AT

AGE

93.

LEARNING TOOLS
COLLEAGUES AND

by Scott Thomas

STUDENTS REMEMBER
HIM .

Astudent's perspective:
THE CHALLENGE TO

SUSTAIN THE HUMAN -

ITY

WITHIN

US

Department Honored
AMERICAN .JOURNAL OF

32

Resemh News

EPIDEMIOLOGY DEDI-

CATES

SPECIAL

TO UB' S

Alumni

ISSUE

DEPARTMENT
REUNION DAY

by F. Michael Elliot

OF

SOCIAL

AND

PREFESTIVITIES PLANNED

VENTIVE

by Lois Baker

Cover iiiU&gt;Irolion by Wh~ney Shermon.

MEDICINE

38

Class notes

�PHOTOGRAPHS BY fRANK CESARIO

OuT WITH THE

'

IN WITHTHE
BY S. A.

UNGER

-UNDERGRADUATE CuRRicULUM REsTRUCTURED
TO INCLUDE PROBLEM- BASED LEARNING

Changes are currently taking place in medical school curricula
that can only be compared in magnitude to changes that took place more than 30 years ago,
when curricula were restructured in response to physician shortages in select specialty areas.
Ironically, while the changes several decades ago were
fostered by a need to include new, specialized knowledge in
the curriculum, today's changes are in large part motivated
by an admission that the body of knowledge, especially in the
basic sciences, has grown so large and complex that no
person can be expected to absorb it all-not in four years of
medical school, not even in a lifetime.
Enter the concept of lifelong learning. Instead of trying to
teach medical students everything they could possibly need
to know about a seemingly endless number of subjects,
educators at the University at Buffalo School of Medicine and
Biomedical Sciences and other institutions worldwide are
exploring a new concept: What about teaching students to

0

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master processes whereby they can teach themselves how to
learn whatever it is they need to learn-using as their base a
strong fundamental knowledge of the basic sciences? As in
the real world of medical practice, this new form of learning
is necessitated when a case is encountered, along with its
specific problems.
The method being used to foster learning in this way is
called problem-based learning; in a larger context, it is also
referred to as case-based learning.
At UB's medical school, problem-based learning (PBL) is
the foundation upon which the undergraduate curriculum
for the basic sciences has been dramatically restructured to
include a new two-year course called the Scientific Basis of

Physician

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�It is this rethinking of learning
methods that has
led medical educators to focus on the
development of
courses that utilize
PBL, which emphasizes learning in
small, self-directed,
s tuden t-een tered
groups.
A few schoolsincluding Harvard
Medic a l School , Small, self -directed, student-centered groups ore
through its New integral to problem-based learning. Pictured ore
Pathways Program first-year students with facilitator Joan Boizer, PhD.
-have devoted
their entire curriculum to a PBL format , but at UB , as in most
schools, PBL is used to supplement a scaled-back number of
core lecture courses. "At UB, what we're looking for is a
balance," explains Dennis A. adler, MD, associate dean of
the School of Medicine and Biomedical Sciences. "There is
material that we believe is core material and is most
effectively taught-and certainly more efficiently presented-through didactic lecture. " To effect this balance,
therefore , and to accommodate inclusion of the SBM course,
lecture time at UB has been reduced by the equivalent of
about a day a week. "We did this because we fully expect
about 10 to 15 percent of what is learned through SBM to
be new material," Nadler adds.

Medicine, or SBM. The course was designed by Alan R.
Saltzman, MD , MBA, professor of clinical medicine, clinical
director of the Department of Medicine at Erie County
Medical Center and former chair of UB's Curriculum Committee; and Murray Ettinger, PhD , Distinguished Teaching
Professor of biochemistry. Given that SBM in many ways
reflects a paradigm shift in medical education, it seems apt
that it was launched at the start of the 1996 school year, with
the Class of 2000 the first to be enrolled.
While implementation of SBM has involved growing
pains on the part of both faculty and students, those who
have had firsthand experience with this innovative course
agree that it merits close attention and support as it continues to develop.
lOOKING FOR A BALANCE

At the core of the current changes in medical school curricula is the realization that strictly lecture-based formats
may not be the most effective way to teach today's medical
students, given the ever-expanding body of knowledge that
must be considered. Critics of the traditional, lecture-based
curricula have called into question its tendency to emphasize
rote learning of facts for multiple-choice examinations, its
lack of a meaningful context and its purported failure to
provide students with the problem-solving skills they will
need throughout their careers. They maintain that what
students really should be learning is how to analyze and solve
problems; in other words , how to identify what needs to be
learned, how to find information that can be used to develop
a hypothesis and how to test this hypothesis by acquiring
additional, more targeted data.

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�Is A CouRSE FOR ADULTS
the group must expand and refine the learning
In their first year in the SBM course, students
objectives for the case and agree to a schedule for
are presented with five clinical cases their first
how these objectives will be covered during the
semester and seven, their second semester. In
two and a half weeks allotted.
their second year, they take on six cases each
"The goal of SBM is not diagnosis," emphasemester. A case begins in Butler Auditorium,
sizes Ettinger, "although the students do like to
where the entire class convenes to participate
figure out what's wrong. The goal is to underin its presentation, which involves an actual
stand the underlying scientific basis of what's
patient who sits in front of the auditorium and
happening to the patient: What is the cause of the
is interviewed by Saltzman, who takes a hisdisease, and what is its clinical course in relationtory. Students are expected to fully participate
ship to anatomy, physiology and biochemistry?
in the process, which is punctuated by Saltzman
In the second year, the emphasis is on the underprodding them to ask questions of the patient.
lying microbiology, immunology, pathology and
Behind Saltzman and the patient, Ettinger is at
pharmacology of the disease."
the chalkboard taking notes under the headutside of these small
ingsofQuestions, Hypotheses, Tests and Learngroups, students are
ing Issues. At the close of this 90-minute sesexpected to find and
sion, the students have an opportunity to talk
read full-length pawith the patient or the faculty individually.
pers about every
This marks the start of their case and in the
learning issue, not
weeks that follow, the class breaks into 17
limiting themselves
groups of eight to nine students, joined by a
to medical textfaculty member who serves in a clearly defined
books, abstracts or scant
role as "facilitator" of the group. Each small
summaries from Web sites. To that end, students
group meets for two 90-minute sessions a week
receive training in how to conduct computer
for two and a half weeks, for a total of five
searches for medical literature and how to idensessions per case. At the start of the first smalltify papers that are appropriate to the learning
group meeting, students are given a written
issues for each case.
summary of the case, prepared by Saltzman, as
In the ensuing small-group discussions, the
well as laboratory
faculty facilitator
tests results from
serves as a guidethe patient. With
not as a teacherthis information
expert-to make
in hand, the stusure that each memdents and their faber of the group
cilitator embark
contributes signifion their journey
cantly to all aspects
into the new
of the discussion
world ofPBL
and that all the
Giving struclearning issues are
ture to this procovered in depth.
cess are clearly
Students are encourdelineated objecaged to facilitate
tives for each
discussion as well.
session as defined
During its final
in the course outmeeting on the case,
line. As a result,
the group takes an
in the first meeting ,
DESIGNERS OF THE SCIENTIFIC
exam, following the same
students know it's improcesses used throughout
BASIS OF MEDICINE COURSE.
perative that they review
the earlier discussions. The
MuRRAY ETTINGER, PHD, LEFT:
the facts of the case and
students are free to refer to
AND ALAN SALTZMAN , MD. MBA.
any clinical data they
their notes throughout the
have on the patient. Next,
exam and conclude by

THIS

"lT MAKES THE
CASE MUCH MORE
MEMORABLE TO
HAVE A PATIENT
THERE," SAYS

MElJI,SA WOlf.
A SECOND-YEAR
STUDENT. "lT
CAN BE VERY
EMOTIONAL.

I

REMEMBER ONE
CASE WE HAD
WHERE THE
PATIENT HAD
CYSTIC FIBROSIS
AND SHE
EXPLAINED TO US
ITS IMPACT ON
HER LIFE.
KNOW

I

I

WOULDN'T HAVE
FELT THE SAME IF

I

HAD JUST READ

ABOUT HER CASE."

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�turning in one paper that reflects their combined effort. Grades are based 70 percent on
participation and 30 percent on content, using
the same grade scale that is used in the core
lecture courses. "This is a course for adults ,"
Ettinger emphasizes. "It's not grade oriented in
the traditional sense: The biggest part of the
'grade' students receive is a detailed evaluation
of how he or she participated in the group. In
essence, the 'exams' are closure exercises that
continue the learning process."
"Basically, what happens in PBL is that education is no longer controlled by the faculty,"
says Saltzman. "The education process now
becomes much more student-focused and student-driven because the students are really the
ones who decide what they need to learn to
understand the case." A key to making this
process work is the fact that the cases are
carefully selected in an attempt to integrate
them with the overall curriculum. "We meet
with faculty to learn what material won 't be
covered in detail-or at all-in the lectures and
then we pick cases that represent specific common diseases that correlate with these areas. By
selecting cases in this way, we know students
will choose the right learning objectives,"
Saltzman explains.

NoBODY

ELsE IN THE

WoRLD DoEs

THIS

What makes PBL most effective, its proponents contend , is that it lends relevancy to
material by presenting the basic sciences
within the context of actual clinical problems, a method that has been shown to
improve recall. "Problem-based learning is

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Physician

really a model that comes
from education that says you
learn and retain better if you
do things in context," adler
says. "And there's good evidence that it works; that's why
it's used in a wide variety of
educational settings now, not
just in medicine. "
Further impetus for the
push toward PBL has come
from the Association of American Medical Colleges, the accrediting organization for
medical schools . "Since the
mid-I980s, the AAMC has
been on a push to reduce the
amount of curricular time in order to get students involved as more active learners," says
Saltzman. "Basically, they've bought into the
concept of PBL, so when they come around to
accredit schools, one of the things they look at
is how much time a school devotes to scheduled
activities, such as lectures and labs , versus other
learning formats. "
PBL has also drawn attention as a means of
stimulating students to choose careers in primary care in order to meet physician-supply
demands resulting from dramatic changes in
the delivery of health care nationwide. "There
are different ways of teaching and getting students interested in primary care," says Saltzman,
"and one of the ways to do that is to introduce
them to patients' experiences early in their
medical education."
A unique way that the SBM course brings
clinical relevancy to PBL is its inclusion of the
"real" patient at the start of each case, as opposed to presenting the case on paper. "Dr.
Ettinger and I had some things we wanted to do
when we designed this course," Saltzman says,
"and one of the things we wanted to do is
introduce each case with an actual patient. We
didn't know at the time that nobody else in the
world does this, although I know of one school
that brings a patient in at the end of a case to
wrap it up. "
"It makes the case much more memorable to
have a patient there," says Melissa Wolf, a
second-year student. "It can be very emotional.
I remember one case we had where the patient
had cystic fibrosis and she explained its impact
on her life. I know I wouldn't have felt the same

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"T HE BEGINNING
WAS PRETTY
TOUCH AND GO,"
SAYS SECONDYEAR STUDENT

USLif
CHAMBtRLAI '\i .
" FoR SOME OF
THE CASES, T H E
FOCUS WASN'T
CLEAR AND WE
DIDN'T HAVE THE
MED ICAL
BACKGROUND TO
BASE OUR
D ISCUSS IONS
ON .. .
H owEvER,

I

ATTRI BUTE T H IS
TO T H E COURSE
BE I NG NEW LAST
YEAR; THIS YEAR
JT's IMPROVED
TREMENDOUSLY."

�if I had just read about her case; I wouldn't have known what
was going on inside her and I feel the personal aspects of her
disease would have been glossed over. With a real patient, I
relate to the person, not just the disease. "
ope Cawdery, a second-year student, says she was pleasantly surprised when her preceptor for her
externship program last summer
said to her, "You know a lot for a
first-year student. " She says she
told him, "It's all SBM." Cawdery
says further that one reason she's
learning so much from the course
is "I get to pick what I'm interested in."
Another key to making the course work, Ettinger feels, is
that students are expected to do their own literature searches,
as opposed to being told what to read. "I have seen that the
real power of this course is that students go out and read
different things," he says, "and when they come back the
typical student doesn't necessarily have a good grasp of
anything, and they know it! But what happens in a very
relaxed, fun way-and it's a marvel to witness-is that by
having read different papers, the students really complement
each other's understanding during the small-group meetings
and a whole lot crystallizes. It's incredible what can come out
of these discussions; they really put it together. Our medical
students are awfully good at this."
THE

Urs

-LEARN!

AND DowNs
G ALO GSIDE FACLLTY

Facilitators for the groups are drawn from both clinical and
basic science faculty. "This is a very faculty-intensive course,"
Saltzman says, "and finding people who want to facilitate has
turned out to be one of our biggest challenges-to free up one
person from a couple of hours of lecturing doesn't help us
come up with the 80 facilitators we need a year. And as the
pressure on productivity increases for all faculty- in the lab

or in the clinic- the time they feel they can allocate for
'optional' activities diminishes."
onetheless, faculty have stepped forward and Saltzman
and Ettinger hope interest will con tinue to grow. The first
group of facilitators was trained in the fall of 1996, when the
course began. "They learned alongside the students," says
Saltzman, "and the students were exceptionally patient with
the process and helped us out a lot. We were trying some
things that just weren't working, so we made many changes
to the course based on their input."
"The beginning was pretty touch and go," says secondyear student Leslie Chamberlain. "For some of the cases, the
focus wasn't clear and we didn't have the medical background
to base our discussions on. For example, we had a case on
sickle cell, but we didn't yet have a basis for the disease given
to us in our biochemistry course. However, I attribute this to
the course being new last year; this year it's improved tremendously. "
Chamberlain says the facilitators were very receptive to
criticism, and that has made all the difference. "They made us
appreciate the course and made us feel we had some say in it.
They didn't just force it on us," she says.
Defining what role the facilitator plays in the group has not
been without controversy. "We discussed this ad infinitum
when we were developing the course," Ettinger recalls. However, he says several groups independently came to the same
conclusion: The facilitator is not an expert in the subject area
and is not supposed to supply information to the group.
ot all the students agree with this conclusion, however,
and the role of the facilitator continues to be a point of
discussion for both students and faculty. Second-year studen t
Andrew Mayer says, "I think facilitators should be sufficiently conversant with the material we're discussing"; however, he does concur that "they shouldn't dominate the
discussion."
"They're not the classic teacher," says Saltzman, who ,
along with Ettinger, also serves as a group facilitator. "Rather,

"PBL IS SOMETHING OF A CONTRADICTION,'' SAYS CHARLES LAU,
A SECOND-YEAR STUDENT. "ON THE ONE HAND, I'M LEARNING
TEAMWORK- HOW TO WORK WITH PEOPLE WITH DIFFERENT
PERSONALITIES- YET, ON THE OTHER HAND, I'M BEING PREPARED TO BE
A VERY INDEPENDENT PHYSICIAN , CAPABLE OF LEARNING THINGS ON
MY OWN , AS NEEDED, FOR THE REST OF MY LIFE."

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�the job of a facilitator
is to help make sure
that everybody participates all the time; that
the group maintains its
focus and that the students go into a decent
depth about each issue. They're also supposed to routinely foster a period of open
discussion by the
group about how the
group is working."
Midway through the
course and again at its
conclusion, facilitators
complete
written
evaluations of the students; the students also
evaluate their own individual performance, as well as that of the facilitator.
When students do voice a concern about the role of the
facilitators in SBM, Ettinger says, their concerns tend to focus
on whether the small-group, PBL format, in general, is
conducive to learning for them as individuals. Roy Vongtama,
a second-year student, is a case in point: "In a lecture,
material is presented in a systematic way by individuals
whose knowledge in their field is recognized. As a result, I
think I comprehend the material more, and retain more, and
I also am more inclined to accept its veracity-as opposed to
discussing the material with classmates and a facilitator
whose knowledge base may be limited. However, I know I
may be biased in this view because of my years of experience
with the lecture format."
CoNFRONT!

needed, for the rest of my life."
For first-year student Marina Zaydman, the small-group
format has helped her successfully confront a very personal
challenge: "I have always had a major problem with being
shy, so being in my group has really helped me open up,
mostly because we all respect each other. I'm feeling less and
less uncomfortable speaking up, and I'm even noticing a
change at my preceptorship because I'm able to talk with the
patients quite easily. It's the greatest. Being shy used to hang
over my head like a ton of bricks."
THE GREATEST CHALLENGE REMAI

G AND RrsoLVING PROBLEMS

As for day-to-day dynamics within the small groups themselves, students and faculty alike agree that, for the most part,
the members get along remarkably well. So well, in fact, that
groups are purposely disbanded and reformed with different
members at the close of each semester-a tactic designed to
help prepare them to interact with the multidisciplinary
teams they will be a part of as physicians.
Problems, when they do occur, often stem from a group
member being either too dominating or too quiet; however,
facilitators are trained to motivate the students to confront
and resolve any interpersonal problems themselves. "PBL is
something of a contradiction," says Charles Lau, a secondyear student. "On the one hand, I'm learning teamworkhow to work with people with different personalities-yet,
on the other hand, I'm being prepared to be a very independent physician, capable of learning things on my own, as

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"Probably the greatest challenge remaining," says Ettinger,
"is for a reformed curriculum to evolve that optimally integrates the core curriculum with the SBM and CPM [Clinical
Practice of Medicine] courses. In order for physicians to
provide excellent care for their patients, they need scientific
knowledge, clinical skills and compassion, as well as consistent approaches for learning, analyzing and solving clinical
problems."
As SBM continues to take shape in the years ahead,
Saltzman and Ettinger are sure they will continue to have lots
of input from students, faculty, facilitators and administrators, and they look forward to further improvements that will
come from this process.
After all, processes geared to solving problems are what
these two educators are primarily interested in, and what
they find most rewarding in their work is seeing processes
such as PBL translate into learning. "The students are really
remarkable," Saltzman says. "It's amazing how quickly they
learn right from the start what the process is for PBL; they just
run through it: facts , questions, hypotheses, mechanisms,

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�'THE EDUCATION PROCESS NOW BECOMES MUCH MORE STU DENT-FOCUSED
AND STUDENT-DRIVEN BECAUSE THE STUDENTS ARE REALLY THE ONES WHO
DECIDE WHAT THEY NEED TO LEARN TO UNDERSTAND THE CASE."
SALTZMA

.MD.MBA

learning issues .... That's what
Dr. Ettinger and I are really
interested in. If they learn that
process, they are set to learn for
the rest of th eir lives."
And the students do seem
to be learning the process.
"The second-year students are
into their third semester of
this," says Wolf, "and we're
getting to be 'old hands' at it.
At the beginning, we had no
idea where to go with PBL,
but now we really go through
the routine fast for each caseit almost gets mechan ica l
at times. "
Who knows, maybe someday Wolf and her Class of 2000
will be making their own brave
attempt to take the rote out of
learning. +

THE GENESIS OF THE SciENTIFIC BAsis OF MEDICINE CouRSE AT UB
he Scientific Basis of Medicine (SBM)course is
adirect outcome of a report issued in1991by
the UB School of Medicine and Biomedical Sciences'
Task Force on Undergraduate Medical Education, cochaired by Charles M. Serverin, MD, PhD, associate
professor of anatomy and cell biology; and Avery Ellis,
MD, PhD, associate professor of medicine and physiology.ln this report-written by the committee's chairs
with assistance from Dennis A. Nadler, MD, associate
dean in the Office of Medical Education--&lt;hanges to curriculum were
recommended to better "prepare students for the practice of medicine inthe
21st century." Akey objective toward meeting this goal was to stimulate

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students' interests in pursuing primary-care careers by introducing them to
clinical experiences in their first two years. To accomplish this, the report in part
proposed designing a course in which students could "learn basic medical
science in a clinical context that illustrates for every student the importance of
basic science knowledge for the clinician."
Further impetus for the SBM course also came indirectly from athree-year,
$600,000 grant the school received in 1994 from the Robert Wood Johnson
Foundation to fund UB's Primary Care Practice Initiative. One of the overall
goals of this initiative is to revamp the medical school curriculum to more
closely link clinical experiences to the basic sciences, as well as to emphasize
problem solving and self-learning, explains Nadler, whose Office of Medical
Education provides ongoing support for the multidisciplinary SBM course. +

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�FACUL1Y EXPERIENCING A LEARNING CURVE

l:o!

n many ways, the move to- facilitator for SBM, but also helps train the discussion in a different direction."
ward problem-based learning new facilitators for the course. He and
Another aspect of traditional teaching
(PBL) in UB's medical education other faculty work closely with Judith that facilitators must leave behind them,
curriculum has been as big a tran- Shipengrover, PhD, a medical education according to Shipengrover, is the familsition for faculty as it has been specialist with the Office of Generalist iar practice of dividing up research tasks
for students. Stanley Spurgeon, Initiatives in UB's medical school. Both among group members for the sake of
MD, clinical assistant profes- educators agree that faculty who serve as efficiency. "In group sessions this apsor at UB and an emergency facilitators in the SBM course are experi- proach only replaces teacher-delivered
room physician for the past 20 encing a paradigm shift in teaching lectures with mini-lectures delivered by
years, has had experience both methods as much as the students are the students as they report their findings,
as a traditional lecturer and, experiencing a shift in learning methods. while the rest of the group listens," she
now, as a facilitator for the
"It's really difficult letting loose of says. "Although counterintuitive and
.)
......, Scientific Basis of Medi- the 'I'm-the-expert' perspective," says seemingly less efficient, the redundancy
cine (SBM) course. "Actually, the role Spurgeon. "I have found that the most and scattershot approach of the PBL
of facilitator is probably easier for me important thing a facilitator needs to method, in which all group members
than for some because in the clinical learn to do is keep his mouth shut."
research every learning issue, fosters realsetting, we frequently teach in small
Shipengrover says the paradigm shift time discussion and problem solving as
groups," he says. "When attending phy- for faculty involves sevstudents work to sift and
sicians, interns and residents do rounds eral key changes in persort what they know or
"IN THE PAST
in a hospital and come across some- spective related to what
don't know about each isFACULTY HAVE BEEN
thing involving a patient they're not Spurgeon has experisue
based on their collecIN CONTROL OF
familiar with, in essence that becomes enced. "Part of it is trust,"
findings."
tive
THE DELIVERY
defined as a learning issue. Everyone is she says. "In the past facSpurgeon has experiOF INFORMATION
enced firsthand all these
given the assignment to learn about it ulty have been in control
NOT NECESSARILY
and give a short summary report the of the delivery of infordilemmas; however, he
T HE RECEIVING OF
is very motivated to connext day. So the small-group, problem- mation-not necessarily
IT- BUT CERTAINLY
based, student-directed model for learn- the receiving of it-but
tinue along his own learnITS DELIVERY.
ing has been used in clinical medicine certainly its delivery,
ing curve when he sees
WHICH ISNTTHE
how well the students
for many years."
which isn't the case with
CASE WITH PBL."
In the past, though, Spurgeon says, PBL So at some level you
progress within the PBL
medical students had to "flounder have to trust that the stuformat. "Most of the
along," essentially teaching themselves dents can and will do what it takes to time," he says, "if you allow a group to
the processes involved in PBL "By our learn-that's the 'Eureka' moment with attack a concept and go at it, they may
third year, we did have the basic build- PBL You let the students confront the not go in a straight line, but almost
ing blocks for problem-based learning, problem, realize what they don't know, always they get to where they need to be
having picked them up from working then go and find out what they need to going; they get it right."
with residents and interns," he says. solve it."
Shipengrover, too, sees much merit in
"But it would have been helpful if we
A second area of transition the PBL format, but feels strongly that
had been taught these processes in a Shipengrover has identified is that of facilitators should be encouraged to demore formal way earlier on."
knowing when to intervene in a group's vote more attention to working with the
Spurgeon says he became interested discussion. "It's a judgment call that students to more clearly define what exin teaching when he was a fourth-year takes a lot of practice," she says. "As an actly the process is that they are experistudent at Indiana University School of expert-turned-facilitator, there's a con- encing in the group. "I feel there should
Medicine. "I began teaching the third- stant push and pull about when, for always be a learning objective related to
year students," he says, "because I re- example, to speak up and tell the stu- the group process itself," she says. "I
membered how helpful the students were dents the answer to an issue they've think we're missing a lot if we don't make
who had made the transition ahead of me been struggling with and when to sim- it part of the facilitator's role to help the
and I wanted to help in the same way."
ply point them toward the solution students see and understand the larger
Today, Spurgeon not only serves as a through strategic questions that move framework they're working within."

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J. . . . . . . . . . . . . . . . . . . . . . . . . ._____________________.

�APhysician Whose Dreams
-and Work-Are

WHE

her family's home in Elmira, New York ,
staring up at the stars, as her father
discussed the constellations. A pilot
during World War II, he was the one
who told her about Apollo l3's mishaps
after the now-famous warning, "Houston , we have a problem," was uttered
from the spacecraft.
At an age when many girls are into
dolls , DeBlock was caught up with the
space race. But back then, the world
hadn't met Christa McAuliffe. "The Right
Stuff' meant, in no small part, testosterone. Yet no one tried telling DeBlock the
stars were no place for a woman. "We
didn't have sexual barriers growing up ,"
she says. "I have an older sister who
graduated from college in 1968-she
was a dorm-mate of Hillary Clinton at
Wellesley-and I thought that she was
one of these women who was forging
the way for me. So we were talking this
summer about that, and I asked her if
she found that difficult. Her comment
was that she never noticed anything.
"There were four girls and one boy in
my family, and our parents allowed us
to make our mistakes and choose what
we wanted to do. And that changed our
mind-set 100 percent.
"Yes , I notice that I'm the only woman
sitting in the room [at the space center].
But I don't let that affect my behavior. "
As a teenager, DeBlock's initial exposure to the world of medicine didn't
leave her as starry-eyed as space. When
she was in high school, her next-door
neighbor, a physician, got her a job
performing electrocardiograms at the
local hospital.
"At first I really hated it," she recalls.

SHE WAS SIX WEEKS OLD , Heidi DeBlock took her

first ride in a glider. When she was six years old, she
marveled as Neil Armstrong took "one small step for
man, one giant leap for mankind."
Her research there focuses on how
As a physician, she has parlayed her
zero
gravity affects astronauts' hearts.
fascination with the final frontier into a
regular stint at Houston's Lyndon B. The results of her biggest project, in
johnson Space Center. "Space is fasci- which she examined the heart rates of
nating because it is so vast, and so little seven astronauts who had gone on space
is known about it," says DeBlock, Class walks between 1990 and 1993 , were
of 1990, a visiting scientist at the center's published in the Apri.l1997 issue of the
cardiovascular lab. "I love science, and American]oumal of Cardiology.
the science involved in this is
And that's just the beginso rich. "
ning . Construction of the
BY
Ironically, DeBlock's NASA
space station is scheduled to
NICOLE
begin next year, and her findconnection with the great unPERADOTTO
known began far from it: in the
ings will be crucial once it is
basement of UB's medical
in operation. "The arrhythschool. There, a visiting professor giving mia research is important because we
a lecture on a heart drug briefly discussed want to make sure there are no ill
her sabbatical at the space center. After effects on the astronauts' heart rhythms
the talk, DeBlock, then a second-year when they're up there ," she says. "We
student, approached the teacher and have to make absolutely sure that it's
asked for names of people she could safe for them. "
For now, in-flight data is as close as
contact in Houston. She made the calls,
had good credentials and, in her fourth DeBlock gets to the launchpad. She was
year, was invited for a month-long once invited to watch a liftoff-but she
had to scrub when she couldn't find a
internship.
baby-sitter
for her three daughters .
"Lo and behold, everything clicked
This year she was among close to
there," she says. "They just kept inviting
me back, and I kept going back." For one 3,000 candidates vying for one of the
month every year and a half, DeBlock most elite callings in the world: astrofrees herself of her duties at Albany Medi- naut. Although she didn't get an intercal Center, where she is an intensivist in view, she plans to try again next year.
the surgical intensive care unit, and at And if it happens, she would be fulfillAlbany Medical College, where she is ing the dream of a lifetime.
director of the second-year cardiovascuAs a chi.ld, DeBlock-then Heidi
lar rotation, and travels to Houston.
Frutchy-would sit on the front steps of

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�"The environment was scary to me. 1
just didn't like being in a hospital." The
next summer she warmed up to the job.
And then, a turning point: "l watched
open-heart surgery and thought that
was the greatest thing."
At the University of Rochester, she
majored in astrophysics, paying for her
education by reading Holter monitors
at Strong Memorial Hospital. Both disciplines, huge and unknown in their
own ways, intrigued her curious mind.
During her senior year, she and a PhD
student published an article in an international physics journal on a discovery they had made in the field of
chaos. "By that time, I had learned to
love medicine more and more. 1 didn't
like astrophysics less and less. But after
[the article was published] 1 felt 1 had
accomplished something in physics,
and now it was time to move on to
medicine."
In the two years before starting medical school, DeBlock worked at Strong as
an intensive care unit technician and
got married. She entered UB in the fall of
1986. ln space history, it was a signifi-

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"lt was very
Heidi DeBlock, MD, vying to
become on astronaut
dramatic. I think
everyone held
their breath until they heard that the
shuttle was into a safe configuration"meaning it was safe for the astronauts to
disembark.
"And then everyone started hemming
and hawing and
AT THE UNIVERSITY OF ROCHESTER , SHE MAJORED
wondering how long
IN ASTROPHYSICS , PAYING FOR HER EDUCATION
it was going to be
BY READING HOLTER MONITORS AT STRONG
delayed. It's only
MEMORIAL HOSPITAL. BOTH DISCIPLINES, HUGE
then you realize how
much
of these
AND UNKNOWN , INTRIGUED HER CURIOUS MIND .
people's lives are on
While the world's interest in space that space shuttle, and how much goes
has waxed and waned, DeBlock's into it. You can't really realize that until
has only grown with her increased you're there. "
DeBlock's next trip to Houston is in
involvement. She knows that every
blastoff means a potential scientific February. Until then, the scientist and
breakthrough. "l was in a conference her minister-husband are sure to have
room during a launch once, and many an intriguing dinner-table conthere must have been 75 [scientists] versation about the world "out there."
"That's always interesting," she notes,
watching it on a closed-circuit TV.
laughing.
"We never argue, though. "
Two of the three engines ignited and
Between her hectic schedule and varithe one did not. So they had to shut
down the shuttle and abort the ous professional duties, DeBlock relies
on her family to keep her grounded. +
mission immediately.

cant year. Early in it-on january 28the Challenger burst into Games 73 seconds after liftoff. "1 was 23," she remembers with the instant recall you would
expect of a space buff. "I had just moved
from Rochester to Holland, Michigan,
where my husband, Scott, was starting
seminary."

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��MEDICAL STUDENT
EXCHANGE TO

BY

MICHAEL

BEEBE

BRINGS NEW
PERSPECTIVE

VERY PHYSICIAN HAS A HORROR STORY

about getting through

medical school. Few ring as true as those of Maida Secerbegovic,
MD , a 1997 graduate of the University of Tuzla Clinical Medical
Center. That's Tuzla, as in Bosnia, the war-torn former Yugoslav
Republic whose people-let alone its
medical care-have been turned upside down by ethnic fighting.
Secerbegovic, whose medical studies took seven years to complete
due to the constant shelling of her city and hospital by Bosnian Serbs,
just completed a five-week exchange at Children's Hospital of Buffalo
as part of a medical partnership between Buffalo and the Bosnian city.
Earlier last summer, three students from the University at Buffalo's

When they first arrived
at the hospital. the UB
students were shocked
by the damage they
saw, which had b een
caused by hundreds of
shells landing on the
hospital grounds.

School of Medicine and Biomedical Sciences made the journey to Tuzla,
where they saw how a hospital staff missing one-third of its physicians has been handling the medical
care of a city whose population more than doubled to nearly one million during the war.
This was the first time it was deemed safe enough for an exchange of medical students through a
partnership called International Medical Relief of Western New York. Begun by jacob Bergsland, MD,
a Buffalo General Hospital heart surgeon who went to Bosnia in 1994 to
work in a United Nations field hospital, the alliance is the first hospital
partnership in Bosnia supported by the American International Health
Association. It was honored by First Lady Hillary Rodham Clinton in a
October 1996 White House ceremony.
P H 0

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�T

he exchange of medical students almost never happened.
The relief organization did
not want to dilute any of its already
scarce resources, which were needed
to help Tuzla's physicians rebuild
their medical system. The immensity
of the job and the dearth of available
funding seemed to make an exchange
of students a costly extra.
But after hearing how their professors were helping people who truly
needed it, and after becoming acquainted with some of the Bosnian
physicians and nurses who have come
to Buffalo for training, the students
didn't think so.(Recently, the U.S.
government renewed a $2 million
grant that, along with local contributions and donations from the medical
school and Buffalo hospitals, will be used
to assist Bosnia.)
"This program was generated by the
students," says Dennis A. adler, MD,
associate dean at the UB medical school and a clinical
assistant professor of pediatrics. "They decided to do
their own fund-raising. Without that kind of initiative,
we could not have done it. "
The only restriction the medical school put on the
students was that the program would have to be a true
exchange program, with Tuzla students coming to Buffalo to study as well as UB medical school students
spending time in Bosnia.
The student exchange started last summer when the
first group from UB-Lisa Apfel, a second-year student
from Hyde Park, NY; Daniel Avosso , a second-year
student from Long Island, Y; and Won Hee Kim, a thirdyear student from New York City- traveled to Tuzla.
A Muslim-held industrial community about 50 miles
north of Sarajevo, Tuzla suffered considerably during
the war, when it served as a key distribution center for
humanitarian aid. To bring in even more supplies, the
United Nations wanted to open the city's airport. The
Serbs responded by shelling the city.

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When they first arrived at the hospital, the UB students were shocked
by the damage they saw, which had
been caused by hundreds of shells
landing on the hospital grounds during the war. Clinic walls are still
pockmarked by shrapnel. Less immediately obvious was the effect that
years of fighting and treating war
victims had had on the hospital staff
and on the community it served.
During the worst of the fighting
in 1992, there was power only two
hours a day, no telephone service,
little or no pay for doctors for their
long hours and no public transportation. urses sometimes had to walk
three hours just to start their shifts.
Some of the doctors who were able to
leave did; others were pressed into
service in field hospitals at the front.
During the interruption in her studies, Secerbegovic helped give immunizations in the war zone and was nearly hit
by artillery shells. A medical-surgical resident at the
hospital suddenly became the hospital's chief of surgery
when the chief left. There was no more heart surgery, let
alone elective surgery. When they ran out of supplies and
drugs or equipment, the staff had to make do .
Apfel experienced a telling example of this the first
time she walked into the hospital and saw the long line of
patients waiting outside a clinic. There are no longer any
hospital gowns in Tuzla, so men and women alike stood
outside the clinic stripped to the waist. o one complained. It was just part oflife. At least they had some hope
of treatment now.
Riyaz Hassanali, MD, a Buffalo physician specializing in
reconstructive plastic surgery and an advisor to the program, was stunned when he first went to Bosnia. Because
everyone in the medical community had to concentrate on
treating war injuries, no one was caring for the health needs
of the civilian population. "Minor problems
became major problems
because they had not
been treated," he says.
"One of the national
journals published the
pictures we took of patients with untreated tumors because they could not believe the tumors
had progressed to that point."
Apfel and her fellow students were shocked
at how little equipment was left. The nearest
MRI machine was in Budapest, Hungary. There
was a CT scanner at the hospital, but it was

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�thousands of hours past its intended
lifetime. Last summer a Buffalo physician packed a neonatal ventilator into
three suitcases and took it to the Tuzla
hospital, where 7,000 babies a year
were being delivered with no ventilator available.
Contrast that with the experience
Secerbegovic had coming to the
Children's Hospital of Buffalo. In one of the most advanced pediatric hospitals in the country, she spent a
majority of her time helping administer gastrointestinal
tests with equipment not available in her homeland. She
says she asked as often as she could how the American
physicians would handle procedures if they didn't have
the benefit of such advanced technology and equipment.
"This was a great experience. I feel like I can help our
younger students now," she says, in nearly flawless English. (She did not need tutoring from the UB English
professors who go to Bosnia to help physicians with their
language prior to their coming to the United States.)
Hassanali says that Bosnia's lack of resources brings an
interesting twist to the medical education of the American
students who visit: "The students who go there learn
more about the practice of medicine than about the
practice of technology."
They also learn how difficult-and potentially costlyit can be to practice medicine without even the rudiments
of technology. Apfel notes, for example, how Bosnian
physicians looking for blood in stool samples sometimes
miss it because they have to rely on visual examinations,
while American doctors use a simple chemical strip costing
a few cents, with near-perfect results. "The resources are
severely limited in Bosnia," she says. "It was amazing to see
how the staff dealt with it; how they would devise things
while a physician here would order several tests."
Students from both countries also spent time together
outside the hospitals.
1
Secerbegovic, whose parent? took Apfel into their
home in Bosnia, visited her
host's home in Hyde Park
and made a trip to Niagara
Falls during her time in the

rotations at the Tuzla hospital-pediatrics, surgery or
internal medicine-and spent their off-hours exploring
the city and countryside. They included a trip to Sarajevo,
a once breathtakingingly beautiful city that was heavily
damaged during the war.
The medical student exchange program, once thought
to be an expensive extra, is bringing unforeseen benefits,
as the students are bringing to their studies a different
perspective from their visits, viewing the problems and
challenges in both countries with fresh eyes.
ew approaches are going to be needed, notes Hassanali,
since Bosnia is being forced to not only rebuild its health
system, but also to abolish the former centrally controlled
economy of communist Yugoslavia. Every specialty in the
Tuzla Clinic, for example, was once its own fiefdom , with
everything separate-from medical journals to operating
theaters.
Daniel Avosso, who, like most Americans, followed the
war on television and in newspapers, began to see Bosnia in
a different light after his stay there. As he walked through
Tuzla, he saw numerous churches, temples and synagogues
as evidence ofa diversity far wider than the media's portrayal
of only three groups: Serbs, Croats and Muslims.
"I was impressed by the
diversity in Tuzla, the various religions and cultures,"
he says. "It was something
I thought only existed in
America, not in a country
that I thought was not accepting of other cultures."
Hassanali, himselfa refugee from Uganda,
believes other UB medical students who travel
to Bosnia will come to the same conclusions he
has about his practice here: "I realizes how
lucky I am to be in the United States, practicing
in Buffalo, with the tremendous resources we
have available." +

u.s.
Apfel, Avosso and Kim
were given their choice of

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�Communication

E

for Tomorrow's
Physicians

stablishing a pattern of open
and trusting communication
between physician and
patient is more than a
perfunctory gesture of
goodwill at the outset of a professional relationship; it's the foundation for every measure of success
in a clinical practice. How well a
physician communicates with patients affects accuracy of diagnosis, adherence to treatment plans,
patient and physician satisfaction
and-increasingly-incidence of
malpractice suits.
Despite this fact, a focus on technology in medicine over the past
four decades and a subsequent drive
to train "scientific physicians" have
tended to erode awareness of the
need for clinicians to have and cultivate effective interpersonal skills. In
more recent years, however, the emphasis on technological innovation has been
eclipsed by managed care and its focus
on cost effectiveness, which has dramatically changed how health care is
delivered. This, in turn, has provoked
unprecedented criticism from patients
about how they perceive they are being
treated. More often than not, the focus
of their attention-or contention-is
on how well they feel their doctor communicates with them.
In an effort to ensure that medical
students acquire the communication
skills they will need in their future practices-and to help bring the "art" of
medicine back into balance with the
science-a new project is under way at

®

the University at Buffalo to more formally integrate the teaching of effective
communication skills into the medical
school's curriculum. The projectwhich will complement existing efforts
at the undergraduate and residency levels at UB-is being led by Frank
Schimpfhauser, PhD, assistant dean for
educational evaluation and research.
Funding for the project is being provided by a $50,000 grant from the Medical Liability Mutual Insurance Company and the Medical Society of the
State of New York.
L!STE lNG AND RESPONDING
TO CALLS FOR CHANGE

The new communication project is a
direct outgrowth of the Standardized

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BY 5 . A . UNGER

Patient Clinical Competency Program
established at UB's medical school in
1992 with grants from the Macy
Foundation and the National
Board of Medical Examiners. In
large part, this program was begun
in response to concerns that thirdand fourth-year students and
faculty expressed about the curriculum, which they felt did little
to ensure that students had minimal competencies in a wide range
of clinical practice areas, according to Schimpfhauser.
More than 90 percent of the
students surveyed over two classes
felt their opportunities to observe
or be observed in a standard way
were less than adequate. Students
felt that they had not observed
enough physician-patient interactions, that they did not have enough
structured feedback on their own interactions and that their clinical skills training lacked consistency and quality. This
sentiment was paralleled by faculty interest at the national and local level to
develop more effective and consistent
approaches to assessing students'
progress and performance in areas of
history taking, physical examination and
patient communication.
"We realized that we could no longer
just assume that over the course of
their first two or three years in medical
school, students will uniformly acquire
basic clinical practice skills, and we
saw that we needed to develop more
consistent ways to teach and objectively assess the skills relevant to these

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�instructors who will demonstrate positive modeling, continued practice with
and feedback from standardized patients
and, finally, application of the acquired
skills in a clinical setting.
Performance reports will be given to
students, summarizing their attainment
of skill, and plans for the future include
making communication skills a
part of UB's annual
" I ALWAYS TELL MY STUDENTS THAT NO PATIENT WILL EVER
competency exams.
COME TO YOUR OFFICE WITH A WRITTEN TEST SAYING . 'I SEE
"Working with standardized patients
YOU PASSED THIS TEST, SO YOU CAN BE MY DOCTOR ,' INwill provide stuSTEAD, THEY ARE GOING TO JUDGE YOU BY SUCH THINGS AS
dents with an opporYOUR EYE CONTACT, HOW WELL YOU LISTEN AND WHAT
tunity to perfect
their communicaQUESTIONS YOU ASK . PATIENTS WILL MAKE THESE TYPES OF
tions skills without
JUDGMENTS ABOUT YOU EVERY DAY" - JAMES HASSETT, MD
embarrassment
a wide range of clinical procedures and about their lack of experience and withprovide structured feedback in years out consequence to patients," explains
two, three and four, using "report cards" Harry Sultz, DDS, MPH, professor of
and faculty presentations. Expectations Social and Preventive Medicine, and
and performance scoring are based on coinvestigator for the project.
faculty-developed criteria.
"Rather than focus on history tak- WoRKING TO OvERCOME
ing, the physical exam or other specific "PROBLEMS OF PERCEP'fi0:\1"
clinical problems, this project is in- The foremost goal of the new project is to
tended to place a primary focus on give students the interpersonal skills they
students' communication skills within will need to deal sensitively and effecthe context of common, yet sensitive tivelywitha wide range of situations they
and difficult clinical topics and issues," will encounter in their everyday practices, especially situations that can be
says Schimpfhauser.
Currently, Schimpfhauser and his value laden, such as teen pregnancy,
coinvestigators on the project are work- alcoholism or risk of HIV infection.
ing with faculty teams to identify and
Studies have consistently shown that
develop appropriate problems and patients' criticisms of physicians-and
checklists, as well as clinical scenarios approximately 75 percent of all medical
that will be implemented using stan- malpractice suits-can be traced to probdardized patients. Topics and issues will lems of perception about how well painclude, but not be limited to, advanced tients feel their doctors communicate
directives; informed consent; HIV risk; with them, not how well they feel their
Do ot Resuscitate orders; the presen- illness was treated. Specifically, these
tation of bad news; sexually transmitted studies show that patients focus on such
disease; obesity and nutrition; substance concerns as how comfortable the physiabuse; and domestic violence.
cian made them feel, whether they unThe training-set to begin in the spring derstood their treatment options, whether
of 1998-will initially involve medical the physician gave the impression that he
students and residents in the depart- or she listened and truly cared, and
ments of Surgery and Medicine. Their whether the physician explained things
interactions with the standardized pa- in a way that gave them hope.
James Hassett, MD, also a project
tients will be videotaped and critiqued. If
deficiencies are identified, the students coinvestigator, is associate program diwill participate in a five-step remedial rector for residency training in the Deprocess that will include working with partment of Surgery at UB and chair of

areas- including communication
skills," says Schimpfhauser.
Through the program, "standardized
patients"-persons trained to portray
patients and specific scenarios-are first
used to complement preceptor instruction in the Clinical Practice of Medicine
Program for first- and second-year medical students. They are also used to assess

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the Program Director's Committee, a
consortium of committees for all of the
medical school's residency programs. He
works every day with residents as they
learn to interact with patients, and he
feels strongly that communication skills
are the single-most important determinant of success at this level of training.
"For residents in training," he says, "how
well they do depends on how well they
communicate with their peers, with other
professional staff, with patients and with
attending staff. Communication in those
four areas becomes the most crucial factor in whether or not they're going to do
well in a residency program.
"Residents are almost never stressed
by knowledge limitations; rarely does
anything happen to their patients where
just pure knowledge will make a difference," he adds. "There's not that kind of
urgency in the work. However, what
does matter is how well the students can
talk with a patient and find out what's
wrong and how well they can talk with
the patient's family and explain treatment options. I always tell my students
that no patient will ever come to your
office with a written test saying, 'I see
you passed this test, so you can be my
doctor.' Instead, they are going to judge
you by such things as your eye contact,
CONTINUED

ON

PAGE

19

COMMUNICATION SKILLS

[oinvestigotors working to develop the new communications skills training program and to plan the
conference ore:
LISA BENSON, MD, clinical assistant professor of
medicine and consultant; TIMOTHY GABRYEL, MD,
clinical assistant professor of medicine and director of
the Internal Medicine Residency Program at Millard
Fillmore Hospital; JAMES HASSETT, MD, professor of
surgery and associate director of the Surgical Residency Program; DENNIS A. NADLER, MD, associate
dean for curriculum and student affairs, Office of
Medical Education; STANLEY SPURGEON, MD, clinical
assistant professor of emergency medicine and medical director for the Standardized Patient Clinical Competency Program; HARRY Sum, DDS, MPH, professor of social and preventive medicine and director of
Health Services Research; KAREN ZINNER STROM, PHD,
trainer/ evaluator, for the Standardized Patient Clinical Competency Program.

�The Challenge to Sustain
the Humanity Within Us
BY

F .

MICHAEL

ELLIOT

last June gave me a sense of
accomplishment and brought closure to a period of
exploration and growth. The transition to medical school
represented a deliberate and refreshing step into a world
of new experiences, ideas and people.
RADUATI G FROM COLLEGE

The past few months have been a
period of intellectual discovery and personal introspection. The adjustment to
the faster pace and greater expectations
of medical school has been difficult, as I
believe it has been for many. What is
most challenging, however, is the confrontation each of us must undergo with
our own limitations despite our desire
for perfection. The pressure to master
knowledge becomes the crucible through
which our perseverance is tested, strained
and strengthened. Although tedious and
consuming, the process of learning inscribes within us the vocabulary through
which we will communicate as future
teachers, scholars and healers.
As we prepare to become witnesses
to the suffering of people, students must
also confront and accept the limitations
of medicine. Our knowledge of the human body and the causes of its pathologies has always been, and will certainly
continue to be, incomplete. As science
provides medicine with new routes of
observing and deconstructing the
mechanisms within our cells and organs , new questions will overshadow
the past discoveries. Advances in biotechnology conquer yesterday's diseases
only to be rendered impotent by the

®

emergent pathogens of tomorrow. The
search for the breakthrough is over:
Victories over disease are now measured in cautious, incremental steps.
Bold efforts to cure cancer and AIDS are
now directed toward attempts to manage these diseases as chronic, long-term
conditions. Economic forces now significantly influence the direction of biomedical research and public health
policy. Escalating health-care costs have
invited and indefinitely ensured the fu-

spite these obstacles, the art of medicine
perseveres as the means through which
human suffering is understood and alleviated. Because those who suffer most
acutely are often the least spoken for and
soonest forgotten, it is often the physician who must act as sole witness ,
advocate and healer. Although the progression of a disease and the inevitability
of death may be beyond a physician's

THE INTERACTION BETWEEN DOCTOR AND PATIENT IS MORE
FRAGILE AND INTIMATE THAN I HAD IMAGINED : IT IS A PRECIOUS FORM OF COMMUNICATION THAT SELDOM OCCURS
BETWEEN HUMAN BEINGS .

ture dominance of managed care. The
consequent loss of physician autonomy
has forced doctors to reexamine and
possibly redefine the relationships they
share with their patients.
It is what the field of medicine aspires
to accomplish that continues to compel
students to become doctors in this increasingly arduous social landscape. De-

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control, his capacity to address pain may
not. What seems to distinguish the
physician from other vocations is his
consciousness of this pain and his willingness to alleviate the consequent
suffering. It is through communication
that this healing occurs, as the patient's
vulnerability and uncertainty is abated
by an understanding of what afflicts him.

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�The clinical experiences during this
first semester have been a fulfilling opportunity for me to experience medicine beyond the basic sciences. The very
act of taking a history with a patient is
profound for a student, now entrusted
with the private pain and frailties of
others. The interaction between doctor
and patient is more fragile and intimate
than I had imagined: It is a precious
form of communication that seldom occurs between human beings. While shadowing a doctor during a preceptorship,
I found myself an observer of two worlds,
remembering myself once as a patient
but now projecting myself as a future
doctor. Before I am fully equipped with
this new medical education, these few
visits have allowed me to see patients
from the uncomfortable perspective of
someone who is helpless to heal them.
Although I cannot discern them yet,
these patients have symptoms I will
soon recognize and diseases I will one
day diagnose. Until then, however, I am
grateful for their kind patience as I
fumble with my stethoscope.
The frenetic pace of this first semester
has increased my appreciation for the

occasional moment of casual diversion
or personal introspection. I have looked
forward to seeing my family during the
holidays and breaks, more acutely aware
of the brisk passage of time. It is paradoxical that this education through which
we seek the ability to heal others requires
that we devote so much time away from
people, immersed in study. We have chosen to devote our lives to the rigorous
study of medicine, a pursuit demanding
personal sacrifice for what we believe is a
noble end. The challenge is to accomplish this task while nurturing and sustaining the humanity within us that has
compelled us from the beginning. +
COMMUNICATION SKILLS

(FROM

PG 17)

how well you listen and what questions
you ask. Patients will make these types
of judgments about you every day. "
The only way students are going to
learn these skills, Hassett says, is through
practice and appropriate feedback. "This
is what Dr. Schimpfhauser is doing with
standardized patients. The reiteration
of a format in a standardized way is
critical to training; it's the concept of
'practice makes perfect."'

TooLs FOR ToMORRow
In addition to training students, the methods developed in this project will provide
faculty with objective and systematic
means of assessing performance in the
area of interpersonal skills. "In medical
school you have a variety of very good
evaluation tools to test cognitive competencies," Hassett says. "However, there
are few tools to evaluate skills. You have
a history of how well the student performed in college, but we are finding that
these records are not always predictive,
so really there currently are no methods
of testing how well students will be able
to interact with patients. With this project,
Dr. Schimpfhauser is working to develop
this type of tool. Once it's completed, it
will be very helpful for faculty because it
will allow us to train against a precise
standard, a standard that will help us
make sure students are acquiring the
skills they will need to become better
doctors-and better people." +
A final outcome of the projecl ru•i/1 be to hold a bes/pmclices confermce in Buffalo in the fall of / 998 in
'"'-'hich teaching techniques, diniml simulation packages
and assessment tools developedfor the project rmd in use
at other medical school.r u::iH br.rhored 11:irh eiluca7orsinvitedfrom mediml schools throughout Nt'"'-• Yori.'Siale.

O NLY O NE INVESTMENT
LASTS A LIFETIME
• Exceptional college placement record
• Challenging curriculum with
14 Advanced Placement courses
• tate of the art visual and performing arts center
• More than 60 interscholastic sports team
• Comprehensive community service projects
• Average class size is 15
• Financial aid avai lable
Admissions tests on these
Saturdays at 9:00 a. m.:
January 24, February 28
To reserve a place for testing or for
additional information, please call:
ICHOLS MIDDLESCHOOL, 175 Nottingham Terr., NICHOLS UPPER SCHOOL, 1250 Amherst St.

875--8212

Acceptance 1s granted to qualified students w1thout regard to race, color, rehg1on or nanonal ongm.

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NICHOLS
SCHOOL

�New Medical Computing Lab Opens
medical student peers intently at the computer screen,
working her way through a histology tutorial program.
Layer by layer, the structure of a tissue section reveals
itself-accompanied by review questions, gentle corrections and the kind of patience only a machine can muster.
In a thousand variations, that's the worked to each other and ready to go
scene being replayed in the new Medical to work with quick Internet connecComputing Lab that opened in August tions and access to Medline, Hubnet
1997 at the University at Buffalo's School and other medical databases.
of Medicine and Biomedical
The lab is open 8 a.m. to
BY
Sciences. Combining a new age
10 p .m. , weekdays, and dayof computer technology with
light hours on the weekSCOTT
the accumulated knowledge of
ends-plenty of time for harTHO AS
centuries of study, the lab is
ried students to fit in one last
making medical education
Internet search for a missing
more accessible to the first generation of citation, or to type that paper that's due
students who've grown up with the desk- tomorrow.
top computer.
Primarily, however, the lab is a place
From such mundane necessities as for teaching and for learning.
word processing to exciting advances in Dannenhoffer refers to it as an "e-tech"
database searching, all the possibilities classroom, in which a professor can work
of computer-assisted learning (and even- at a central station and direct computer,
tually medical practice) are being played VCR and other electronic images to apout in the Cary Hall lab.
pear on students' individual monitors, or
"This has been in the planning for project them on a screen using one of two
three or four years, " says Ray projectors and an audio system. The arDannenhoffer, PhD, director of the rangement allows the professor the flexschool's Office of Medical Computing ibility to move back and forth in his
and faculty member in the Department presentation at the click of a mouse, for
of Anatomy and Cell Biology. "I under- example, or the ability to quickly access
estimated how much the students would
appreciate it: The feeling is, 'The school
has really invested something in my
education. They've put up an infrastructure I can really use."'
The project involved major renovations to the second floor of Cary Hall,
including the removal of walls to create a wide-open room, then a series of
improvements-carpeting, paint, new
furnishings, such as comfortable ergonomic chairs and computer desks
and Laser]et printers-and about 70
Gateway 200 MHz computers, all net-

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a related image when a class discussion
takes an unexpected turn.
What's different about the e-tech
classroom is that the students, too , are
given the tools and the responsibility
for managing their own learning. This
is especially evident in a series of tutorials, such as the histology tutorialdeveloped by John Cotter , PhD ,
professor of anatomical sciences and
opthalmology at UB's medical schoolthat allow students to immerse
themselves in a body of information
until they're satisfied that they've mastered it. There's also a computer sound
system with headphones- useful in a
cardiology session, for example, in
which the student learns to identify
normal and abnormal heart sounds by
listening in a controlled environment.
The medical school's new focus on
problem-based learning, as in the Scientific Basis of Medicine course for firstand second-year students, would be
much more difficult to carry out without
this computer support. For one thing,
problem-based learning demands that
students search out, sort and evaluate
information on their own- something
that computers make exponentially
more efficient than walking through a
labyrinth of library stacks.
"It saves a tremendous amount of time,"
says Amy Van de Water, a second-year
student who's now taking her third
semester of Scientific Basis of Medicine.
"Because we're first- and second-year
medical students, our medical background

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�\
I

is very limited, so you really have no idea and the students can search those for a interactive teachers of diagnostics, even
sometimes what to make of the symptoms particular article and either save it or as general-reference textbooks.
[presented by the class's designated pa- print it out."
"These students are either working
tient]. There are a number of medical
This sort of information manage- directly with the diagnostic programs,
textbooks on-line, so that's a good starting ment is crucial to the emerging field of or logging onto the World Wide Web
point. In some programs you can get a medical informatics, a field that the and looking at particular sites, or logwhole article on-line, rather than trying to next generation of physicians will find ging onto the university library facilifind it in the literature in the library-if themselves encountering every day. ties, looking at papers with regard to
you can find it at all on
new findings .... Many of
the shelves."
the students have had a
THE EMERGENCE OF PRACTICAL APPLICATIONS IN
First-year student
great deal of computer exRob Collard agrees:
perience through the colMEDICAL INFORMATICS MAKES . .. FAMILIARITY
"Here you can go off
lege years. But surpris[WITH COMPUTERS] CRUCIAL TO THE STUDENTS"
and find reliable
ingly, there's a section of
sources of information
the class that is fairly naSUCCESS AS PHYSICIANS.
to attempt to bring
ive as far as computer usdepth to the issues
age is concerned. It's very
raised in class. It's a team approach, and From computerized patient records important that they be given the opporhopefully it leads to a synthesis of is- and billing, to new ways of presenting tunity to begin to use this technology
sues."
and sharing data about patients, to keep- and get some idea of how it all works
As for the amenities of the new com- ing current with the tremendous growth and to overcome their fears. "
puter lab, Van de Water says it's a sig- of medical knowledge, physicians will
The emergence of practical applicanificant improvement over the previous increasingly find the keyboard as tions in medical informatics makes that
lab. "There are more computers avail- necessary as the stethoscope.
familiarity crucial to the students' sucThat's the focus of a course in medi- cess as physicians. As an example,
able to students, so you don't have to
wait," she says. "There are faster and cal informatics for second-year students Spangler points to the Visual Chart, a
better printers here. And the old lab was taught by Robert A. Spangler, MD, an method of presenting patient informanot temperature-controlled, so we were associate professor and director of gradu- tion visually that was developed by
always opening the windows because it ate studies in the Department of Physi- former UB medical school professorjohn
was sweltering."
ology and Biophysics. "We go through Loonsk, now at the University of North
"Because the computer lab is in the things like the structure of databases Carolina. "It's a Windows-based probuilding where teaching takes place, and how to conduct effective searches, a gram that tackles individual patient data
students don't have to go to the library little bit about the Internet as a resource, and displays it in a graphical fashion , so
if they need to do a search in between and then we talk about expert systems," one can, at a glance, get a feeling for the
classes and have only a little bit of time," he says. Those systems include such nature of the problem," Spangler says of
Dannenhoffer says. "And besides the programs as QMR and Iliad, which can the program, which is undergoing field
medical databases that are available, a act as consultants in diagnosing a condi- tests. "It's not just a chart hanging on
lot of the medical journals are on-line tion based on a set of symptoms, as the end of the bed anymore." +

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�Journal Celebrates Innovative UB Research
acuity in the Department of Social and Preventive Medicine at

t "Consumption ofPCB-Contaminated
Fresh Water Fish and Shortened Menthe University at Buffalo School of Medicine and Biomedical strual Cycle Length"- Pauline Mendola,
Sciences have trained some of the most respected epidemiolo- PhD, formerly of UB, now of the EPA
t "Gender Differences in the Relationgists in the United States and produced significant and innova- ship Between Depressive Symptoms and
tive research in cancer, occupational, environmental, nutritional, Alcohol Problems: A Longitudinal Perspective"-Beth Steger Moscato, PhD,
reproductive and cardiovascular epidemiology.
research assistant professor
tionship
of
alcohol
and
breast
cancer,
In recognition of the department's
t "Physical Activity, Obesity and Diabecontributions to the field , the December and relationship of gum disease and tes"-Timothy D. Dye, PhD, a 1990
2, 1997, issue of the American journal of heart disease.
graduate of the department, now
BY
Epidemiology is dedicated to research by t Trevisan was the first to show
at the University of Rochester.
the beneficial dietary effects of
its faculty members and graduates.
The issue begins with hisLOIS
"The publication of this issue cel- olive oil in population-based
torical overviews of the UB
ebrates the rich legacy of the depart- studies.
medical school (which marked
ment and the School of Medicine and t John Vena, PhD, professor
its sesquicentennial in 1996),
Biomedical Sciences," says Maurizio and associate chair, has defined several the department, as well as epidemiolTrevisan, MD, professor and chair of the nutritional and environmental factors ogy in Western ew York, dating back
department. "It affirms the important that influence the risk of bladder to 1843. Graduate Philip C. asca, PhD,
contribution that our training programs cancer.
professor of epidemiology at the Unihave made to the field of epidemiology t Germaine M. Buck, PhD, associate versity of Massachusetts at Amherst,
and prevention."
professor and one of the nation's most writes on current problems and future
Saxon Graham, PhD, one of the pio- respected specialists in epidemiology of opportunities in the field and graduate
neers in the study of the relationship of infertility, in 1994 received one of two Christine B. Ambrosone, PhD, discdiet and disease, spent his career at UB, research fellowships awarded in the usses the new field of mol ecular
where he conducted some of the earliest United States by the Merck Company epidemiology.
studies in the United States on the health foundation and the Society for EpidemiThe final two studies concern the
benefits of a diet high in vegetables ology Research. She is conducting a reliability of study participants' reports
containing beta carotene, now shown to long-term study of tubal ligation.
of lifetime drinking histories (by Marcia
The issue's lead article, "Body Mass Russell, PhD, clinical professor) and of
lower the risk of certain cancers.
Jo L. Freudenheim, PhD, associate Index and Mortality in a General Popu- reports of pap smears, breast exams and
professor, has continued that research lation Sample of Men and Women," mammograms (by Richard B. Warnecke,
and in the past decade has earned a written by Joan M. Dorn, PhD, assistant PhD, formerly ofUB, now of the Univerreputation as one of the nation's leading professor, reports that being overweight sity of Illinois at Chicago).
is a significant mortality risk factor for
nutritional epidemiologists.
Graduates of the department include
women and men less than 65 years old. top officials and/or researchers at the
Other research highlights follow:
Other articles and lead authors int The department was designated as one
ational Cancer Institute, Monsanto
of 15 vanguard centers for the ational clude:
Company, the ational Center for
Institutes of Health's Women's Health t "Lactation History and Breast Cancer Toxicological Research, ewYorkState
Department of Health, Roswell Park
Initiative, one of the largest clinical tri- Risk"-Jo L. Freudenheim, PhD
t
"OxidativeStressandLungFunction"als ever assembled, focusing on diseases
Cancer Institute, Centers for Disease
Holger ]. Schunemann, MD , research Control and Prevention, Illinois Despecific to women.
t More than $12 million in funded re- assistant professor
partment of Public Health , University
search is currently under way, includ- t "Consumption of Contaminated Sport of Massachusetts at Amherst, Univering studies of the effects of lifestyle on Fish from Lake Ontario and Time-to- sity of Iowa and orthern California
lung cancer and heart disease, health Pregnancy, ewYorkAnglerCohort"Cancer Center. +
effects of eating Lake Ontario fish , rela- Germaine M. Buck, PhD

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�Magnificent
BUILDING LOTS

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Dear Colleague:
As a former president of
the University at Buffalo
medical school Alumni
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El
the world. Later, in 1963 , he was a
senior member of the team that performed the first kidney transplant at
that same institution.
After his training was completed, Aust
stayed on the faculty as a scholar of the
American Cancer Society, beginning in
J. BRADLEY AUST LOOKS BACK
1957. "At the University of Minnesota ,"
he recalls , "I worked for Dr. Owen
Harding Wangensteen, who, over the
Bradley Aust, MD, was recognized as University at course of his career, trained 30 chairs of
Buffalo Distinguished Medical Alumnus at a dinner held surgery around the country, including
Dr. Randolph Paine, cochair of surgery
in his honor on September 25, 1997, in Buffalo . A 1949 at UB. "
Discussing trends in medicine that
I graduate of the UB medical school, Aust retired in 1996
influenced career options for physicians
as chair of the Department of Surgery at the University of starting out in the 1950s, Austsays, "My
whole generation went into cardiac surTexas Health Science Center at San Antonio, a position he gery. " However, his plans to do just this
held for 30 years. In a recent interview from his home in changed suddenly one day, when his
mentor and "boss ," Dr. Wangensteen ,
Texas, he shared highlights of his long and eventful career, stopped him in the hallway and engaged
attributing much of his success to exceptional mentoring, him in a conversation in which he
strongly encouraged the young surgeon
collegial teamwork and simply "being in the right place at to pursue oncologic surgery. "It was
clear that if I wanted a job on
the right time ."
staff, I should become a cancer
"The 1950s were a very intersurgeon," Aust says with a
esting time to enter medicine ,"
chuckle.
As is often the case, this
Aust says. Indeed, as his career
unexpected change was positook shape, the young Buffalo
native found he had the good
tive and over time led to new
and unexpected opportunities.
fortune of being able to play an
active-sometimes pioneeringIn 1966, Aust was selected to
role in the unfolding of medical
be the first chair of the Department of Surgery at the Univerhistory. After finishing his studies at UB, Aust went to the Unisity of Texas Health Science
Center at San Antonio. Earlier
versity of Minnesota to serve his
surgical residency, during which
in his career, while at the
University of Minnesota , he
time he discovered an interest in
research and an academic caconducted research related to
studies on endotoxin shock and
reer. His surgical training was
interrupted by two years of ser- J. Bradley Aust, MD, left, receiving Distinguished Medical Alumnus award fromJohn the application of immune
R.Wright, MD, interim dean, UBSchool of Medicine and Biomedical Sciences, center, tolerance to transplantation.
vice as a surgeon during the Koand Jared C. Barlow, MD, president, Medical Alumni Association.
Later, he began to gain national
rean War. Returning to school in
In 1955 , Aust had his first brush recognition through his pioneering clini1952, Aust completed his residency and
fellowships in physiology, oncology and with medical history , when he served cal work in oncologic, vascular and transsurgery, and earned an MS degree in as a junior member of the team at the plantation surgery. Once in Texas, he
physiology and a PhD in surgery as part University ofMinnesota that performed concentrated his efforts on the many
one of the first open-heart surgeries in challenges inherent in building a new
of his research training.

1997 UB Distinguished
Medical Alumnus Named

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department, the practice of oncologic
surgery and the development of improved ways to administer adjuvant chemotherapy.
Aust's move to San Antonio was literally a "ground floor" opportunity, as the
school was in the process of being established. Looking back, he feels this time
and the years that followed were the
most rewarding of his career. "just the
germination of the idea that I could run
a department of surgery was very exciting," he says. "These were heady times.
I had an opportunity to help design the
curriculum, establish a new department
in a new school and train surgeons
according to my own model. "
In addition to his administrative
responsibilities at the Health Science
Center, Aust continued to explore his
clinical research interests and pioneered
isolated perfusion, the administering of

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high doses of chemotherapy locally as a
means to overcome systemic toxicities.
He also found time to serve as president
of a number of medical and surgical
societies, including the Society of Surgical Oncology, and the Association for
Cancer Education, and served as chair
of the Board of Governors of the American College of Surgeons.
Aust is reflective about progress in
the field of oncology, having spent the
last several decades of his career treating cancer patients. "People often ask
me where I think we stand now in our
attempts to treat cancer more effectively, " he says. "I often compare the
conquest of cancer to the conquest of
the atom bomb. When we developed the
atom bomb, we knew all we needed to
know to develop it; we just had to do the
engineering. When we started out to
conquer cancer, we didn't have the basic

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understanding to do the engineering;
we didn't have the basic science. " Today, progress is being made in our understanding of the basic biological processes underlying the genesis of cancer;
that's the understanding from which
progress in the future will stem, he adds.
In retirement, Aust is avidly pursuing one of his favorite hobbies-surgical history-and is hard at work writing
a chronicle of the Health Science Center
at San Antonio. He also remains dedicated to his alma mater by volunteering
his time to serve as a member of the
Dean's Advisory Council for the UB
medical school, traveling to Buffalo three
times a year to meet with the group. He
says being named UB's Distinguished
Medical Alumnus is something he didn't
anticipate and states simply, ''I'm really
honored. " +
-S.A

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Buffalo

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Primary Care Extemsbip Program
Receives $150,000 Grant
n innovative program providing real-life clinical learning opportunities in primary care for University at
Buffalo medical students has received a three-year,
$150,237 grant from the Charles E. Culpeper Foundation of Stamford, Connecticut.
Physician in Training Initiative. The
paid externship exposes first- and
second-year medical students to the
practice of primary care medicine in
community-based settings throughout
Western New York.

Administered by UB's Primary Care
Resource Center, the six-week Medical
Student Summer Externship Program
is recognized as the largest of its kind
in the nation by the American Medical
Student Association 's Generalist

Diane Schwartz, executive director
of the Primary Care Resource Center,
says the Culpeper Foundation grant
will help fund an assessment of ways to
retain UB medical students to practice
primary care in Western New York.
"Our numbers are showing that 50
percent of UB medical school graduates are entering primary care ,"
Schwartz says. "However , the significant issue is retention. With more analysis and evaluation of the primary care
externship program, we will have valuable information on how we can retain
the medical students entering primary
care in Buffalo and the surrounding
areas."
Gathering this information, explains
Schwartz, could have a significant
impact in areas with a health-care
shortage designation , a federal term to
identify areas with too few medical

THE SCHOOL OF MEDICINE AND BIOMEDICAL SCIENCES WISHES TO EXTEND ITS THANKS TO THE FOLLOWING PHYSICIANS WHO SERVED AS PRECEPTORS FOR THE
PRIMARY (ARE SUMMER EXTERN SHIP PROGRAM IN

1997.

EXTERN

PRECEPTOR

FIELD

EXTERN

PRECEPTOR

FI ELD

Renee Abderhalden
Bettina Ackerman
Tomaro Alberti
Ben Alderfer
Romone Alexander
Steve Ambruski
Jell Amodeo
Joyce Anderson
Lynn-Marie Aronico
Stephanie Babcock
Lynn Barnhard
Florence Bero
Anthony J. Caprio
Thomas V. Caprio
Hope Cowdery
Patrick D'Abbracci
Ann DeNordin
Porn Diomontis
Melissa Dilanni
Melissa Dilonni
Louis Domenico Jr.
Holly Drexler
Notosho Frongopolous
Jennifer Griffith
Molly Harrington
Chuck Howorth
Shannon Howe
Shirley Huang
Rashma Katira

Thomas S. Scanlon, MD
Evelyn Hurvitz, MD, FAAP
Ganesh N. Deshponde, MD
Thomas F. Cozza, MD
David Holmes, MD
G. Lawrence McNally, MD
Mork R. Klocke, MD
lone M. Pormington, MD
Nicholas Aquino, MD
Chelikoni VP Varma, MD
Geoffrey Markowski, MD
Geoffrey Markowski, MD
Pat Collins, MD
Donald Robinson, MD
Richard Schifeling, MD
John Fudymo, MD
Geraldine Kelley, MD
Sanford Levy, MD
Anthony 0. Bartholomew, MD
G. Joy Bishop, MD
Shawn Cotton, MD
Mork Swetz, MD
Geoffrey Markowski, MD
Paul Lecat, MD
Theodore Putnam, MD
Richard Schifeling, MD
Margo Krasnoff, MD
Gregory Synder, MD
S. T. Pavon, MD

Internal Medicine
Pediatrics
Pediatrics
Pediatrics
Family Medicine
Pediatrics
Pediatrics
Pediatrics
Medicine/Pediatrics
Pediatrics
Family Medicine
Family Medicine
Family Medicine
Family Medicine
Internal Medicine
Internal Medicine
Internal Medicine
Internal Medicine
Internal Medicine
Internal Medicine
Family Medicine
Family Medicine
Family Medicine
Medicine/Pediatrics
Pediatrics
Internal Medicine
Internal Medicine
Family Medicine
Family Medicine

Margaret Lafferty
Charles Lou
Karen Lee
Judy Lettmon
Jason Lorenc
Rosemarie Mannino
Andrew Moyer
Kara McCunn
Hasit Mehta
Donna J. Peace
Jesenia Pena
Stephen Przynosch
Mory Rose Puthiyomodam
Kevin Robillard
Gretchen Schueckler
Morsilio Seiwell
Tracey Shanahan
Natalie Sikka
Marissa Stumpf
Britto Svoren
Priyo Tahilioni
Roque! Thomas
Judith Toski
Amy Van de Water
Rosalia Viterbo
Michelle Watson
Ryan White
Melissa Wolf
Nora Yip

Barbara Stouter, MD
David Milling, MD
Raphael Wang, MD
Dona Drummond, MD
James Wild, MD
Ellen Rich, MD
Timothy F. Gabryel, MD
Thomas R. Gerbasi, MD
Harry Metcalf, MD
Ellis Gomez, MD
Peter Kowalski, MD
Fronk C. Mezzadri, MD
Colin McMahon, MD
David Thomas, MD
Jack P. Freer, MD
Brian Connolly, MD
Emily Frieden, MD
Jack F. Coyne, MD
Deborah Richter, MD
Peter Kowalski, MD
Colleen Mattimore, MD
Anthony F. Oliva, DO
Leonard Katz, MD
Robert Berke, MD
Peter Winkelstein, MD
Geraldine Kelley, MD
Howard Sperry, MD, MPH
Leonard Katz, MD
Anthony Vetrano, MD

Pediatrics
Medicine
Pediatrics
Family Medicine
Family Medicine
Internal Medicine
Internal Medicine
Pediatrics
Family Medicine
Family Medicine
Family Medicine
Medicine/Pediatrics
Medicine/Pediatrics
Family Medicine
Internal Medicine
Family Medicine
Pediatrics
Pediatrics
Family Medicine
Family Medicine
Pediatrics
Family Medicine
Medicine
Family Medicine
Pediatrics
Internal Medicine
Internal Medicine
Medicine
Pediatrics

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�professionals available.
"It is important to attract students
to practice primary care in these areas,"
Schwartz says. "Developing long-term
relationships with patients and the
community through the externship
program, we believe, provides the
impetus for the medical students to
continue practicing medicine here."
The Culpeper Foundation grant also
will fund stipends for 20 medical students per year to participate in the
externship program, as well as provide
partial funding for an associate director of the program.
The Charles E. Culpeper Foundation is a private, nonprofit charitable
foundation established by the late
Charles E. Culpeper, one of the early
pioneers in the bottling and marketing
of Coca-Cola. The foundation provides approximately $7 million per year
in support of activities in health, education, arts and culture, and the
administration of justice. +

Journal Dedicated to Dr. Helm
he ovember 1997 issueoftheDer-

matologic Surgery journal has been
dedicated to Frederick Helm, MD,
emeritus professor and former chair,
Department of Dermatology, UB
School of Medicine and Biomedical
Sciences, on the occasion of his 70th
birthday. In an editorial comment, Robert A. Schwartz, MD, of The University
of Medicine and Dentistry of ew jersey,
says of Dr. Helm: "His work since the
early 1960s with professors Edmund
Klein, Halina Milgram and Howard L.
Stoll Jr. on skin cancer and its immunotherapy is of extraordinary merit. His
book, Cancer Dermatology, is a first-rate
accomplishment, as are the large number
of book chapters and articles he has written .... The work of Professor Helm and
his colleagues has led to the present era of
unprecedented advances in the study of
etiology, recognition and management
of skin cancer symbolized by the superb
articles in this Special Issue." +

inda Duffy, PhD, associate professor ters, insurance providers and school and
of pediatrics, and scientific director public health officials," she says. "I look
of the Women and Children's Health forward to serving the children of ew
Research Foundation (WCHRF) at York State and intend to promote public
the University at Buffalo School of policy that supports initiatives that help
Medicine and Biomedical Sciences us achieve Health 2000 objectives for
and the Children's Hospital of Buffalo, immunizations." +
has been appointed to New York
State Governor George Pataki's
Advisory Council on Immunizations.
According to Duffy, the appointment provides a vital opportunity to impact immunization
compliance for the children of
Western ewYorkand ewYork
State. "Immunization surveillance
depends on integrated, cooperaLinda Duffy, PhD, associate professor of pediatrics and scientific
tive efforts between primary-care
director
of the Women and Children's Health Research Foundation
physicians, regional referral cen-

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Michael J. Baranski
Marketing Representative

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I

fallacy .... Everyone has a will. The real
question is "Who wrote it? "
If an individual, for whatever reason, doesn't take the time to write a
personal will, the author becomes "the
politicians."
All states, as well as the
m
Co•o•• PHD " ' " '
federal government, have laws that
govern what happens to a person's
ast fall, I had the opportunity to represent the School of Medicine assets if he or she dies without a valid
will or other estate plan. One reason
and Biomedical Sciences at the 17th International Fund Raising there are so few "public service" proWorkshop. It was held near Amsterdam, outside the village of grams promoting the writing of wills
may stem from the government's inNoordwijkerhout, on the North Sea, in a former monastery. terest in the resources of those who
die intestate. Some people are also
Thirty-four countries were represented by a total of 689 delegates.
content with this arrangement. (I once
There were 18 of us from the United States. What a novel experience heard of an immigrant and naturalized citizen of the United States who
to be in such a distinct minority-and yet at the same time, to feel was so happy with the life he had made
here that he wanted his accumulated
totally at home among my peers.
wealth to go to our government.) Most
Participating in this workshop was laws therein. The overwhelming mes- of us, however, prefer to have a more
an adventure I will treasure all my life. sage was that those who included edu- active voice in how our hard-earned
It reinforced my commitment to this cational and charitable organizations resources are used after we are finnoble vocation of institutional advance- in their estate plans did so more for the ished with them.
Recently, I had the privilege of readment, and at least equally important, love of their families and their organimy decision to work on behalf of this zations than for tax benefits. To pro- ing an expertly crafted will. It was
excellent medical school. Together with vide for their families and to direct beautiful, thoughtful and complete. It
fully utilized the gift exDr. Wright, the departclusion
amount of
ment chairs and fac" WHERE THERE' S A WILL , YOU HAVE A SAY ." YOU MAY HAVE
$600,000, currently in
ulty, with alumni and
effect, as legacies to
friends of this instituHEARD IT REPORTED THAT ONLY FOUR IN TEN OF ADULT
children and grandchiltion, I am delighted to
dren. The remainder
be involved in helping
AMERICANS HAVE VALID AND UP-TO- DATE WILLS. FROM ONE
was divided among
to weave the future of
educational and charithis school. It is alPERSPECTIVE . THAT STATEMENT IS A FALLACY . . . . EVERYONE
table organizations,
ready outstanding; fuHAS A WILL. THE REAL QUESTION IS " WHO WROTE IT?"
leaving
no taxes of any
ture philanthropy
sort
to
"Uncle
Sam" or
holds the potential to
"Cousin Gov." One of
enhance and expand
the opportunities available to students, resources to nonprofit organizations, the beneficiaries was the University at
alumni, fellows, faculty and friends.
there has to be an official document Buffalo. The six-figure gift will initiate
Three of the small-group sessions in that governmental authorities recog- a scholarship endowment in memory
which I participated focused on lega- nize. In this country, the document of the individual's daughter. Forever
after, outstanding students at UB will
cies, and how, at their deaths, indi- is a will.
viduals in many different countries
"Where there's a will, you have a benefit from the thoughtful foresight
make gifts to their favorite organiza- say." You may have heard it reported of this individual and those who helped
tions. There are, of course, more simi- that only four in ten of adult Americans to structure the will to meet his wide
larities than differences in these have valid and up-to-date wills. From variety of objectives.
In our office, we frequently receive
prgrams, regardless of country or tax one perspective, that statement is a

AWord from the Director
of Development "'

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�requests for assistance in crafting wills
and other estate plans . For general
questions, I have a variety of booklets
that present overviews of ways to give,
what is essential to include in a will
and what types of gifts bring with
them lifetime benefits to donors. One
even focuses on "Estate Planning for
Today's Woman." All of them include
information regarding the changes
made in the tax laws during the 1997
Congressional Session.
The school is also fortunate to be a
part of a university-wide development
operation, with a planned giving staff
available to assist in specific aspects of
planning one's estate. Each situation
is different; each plan becomes a tapestry, the design of which rests with
the individual and what he or she
wants to accomplish with the resources
available. lf you have questions , our
conversations are confidential. Give
me a call.
Linda]. (Lyn ) Corder is th e associate dean
and direc tor of development for the School of
Medicin e and Bi omedical Sciences. She previously serv ed the sc hool as maj or gifts coordinator
and assi stant dean . +

INFINITI

tal in Little Rock and served as assistant
professor and associate professor of ophthalmology at the University of Arkansas
for Medical Sciences. Reynolds returned
to Buffalo in 1988, when he was named
chief of pediatric ophthalmology at
Children's Hospital.
Currently, Reynolds is the recipient
of a two-year, $436,000 grant from the
National Eye Institute to investigate a
treatment that could prevent retinopathy of prematurity. Characterized by excessive growth of retinal blood vessels in
extremely premature infants, the condition can cause vision degeneration and
blindness. +

James Reynolds,MD, Named
Interim Chair, UB'sDepartment
of Ophthalmology

ames Reynolds, MD , has been appointed interim chair of the Department of Ophthalmology at the University at Buffalo School of Medicine and Biomedical Sciences.
Reynolds, who is an associate professor at the medical school, also serves
as chief of pediatric ophthalmology at
the Children's Hospital of Buffalo. A
graduate ofUB's school of medicine, Class
of1978, Reynolds completed
his ophthalmology residency in Buffalo and fellowship training in Pittsburgh,
after which he became a
clinical instructor and staff
surgeon at the Eye and Ear
Hospital, the Children's Hospital of Pittsburgh and the
University of Pittsburgh
SchoolofMedicine.ln 1983,
he became the chief of pediatric ophthalmology at the
Arkansas Children's Hospi- James Reynolds, MD

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He Was aGiant in His Field
-DAVID KIMBALL MILLER , MD , DIES AT AGE 93

avid Kimball Miller, MD, professor
emeritus at University at Buffalo
School of Medicine and Biomedical
Sciences, died in his sleep at age 93
on October 25, 1997, at the home of
his son, David Rush Miller, in Hilo ,
Hawaii, where he had lived since 1993.
A native of Bloomington, Il, Miller
graduated from Illinois Wesleyan University in 1925 and Harvard Medical
School in 1929. He then served a twoyear internship at Boston City Hospital,
after which he completed a residency at
Rockefeller Institute for Medical Research
in ew York City from 1931-1937.
Miller came to Buffalo's Edward ] .
Meyer Memorial Hospital (now Erie
County Medical Center) in 1937 as director of laboratories, and two years
later he became director of the Department of Medicine at the hospital , a position he held until1967. Also in 1937,
he accepted a teaching position at the
University at Buffalo medical school,
becoming the first full-time faculty member in medicine at the school. "Because
he was the first full-time faculty member in the department, which had a very
strong clinical faculty , it was critical
that he be a master clinician, and this
was a role Dr. Miller fulfilled in a very
amazing way," says james olan, MD,
professor of medicine at UB's School of
Medicine and Biomedical Sciences and
chair of its Department ofMedicine from
1978 to 1995.
"Dr. Miller was recognized by both
academic and volunteer faculty as being
the most superb bedside clinician and
teacher in Western ew York," olan
adds. "He had an encyclopedic knowledge of medicine , but more importantly,
he could assemble small clues about a
patient's illness and arrive at an accurate

diagnosis and effective management plan.
Dr. Miller trained a generation of internists who are among the best clinicians
in this region and throughout the nation.
To this day, many of these physicians still
revere him as the greatest clinician they've
ever encountered. "
From 193 7 to 1968, Miller also served
as cochair of the Department of Medicine at UB 's medical
school, a responsibility
that was shared with the
chief of medicine at the
Buffalo General Hospital.
For many years, the two
hospital-based departments operated largely
independently; however,
with the arrival of Evan
Calkins, MD , in 1961 , as
head of medicine at the Buffalo General
Hospital, and the incorporation of the
then-University of Buffalo into the State
University of New York system, he and
Miller began to work together closely to
develop a university-wide department.
In 1968, Miller volunteered to step
down as cochair of the department in
order for the university to further develop the concept of a single department, according to Calkins.
"Dr. Miller realized the importance
of combining the two departments into
a single, unified department and was
very supportive of me," says Calkins,
who , following a national search, was
selected to serve as its chair. "Dr. Miller
was 100 percent supportive of this transition," he adds. "He was a very generous man and had a great capacity for
seeing the whole picture."
Miller remained active as a professor
of medicine at UB until his retirement in
1974, at which time the university hon-

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ored him with the title of emeritus professor of medicine. In 1984, in further
recognition of his skill as a medical diagnostician and for his commitment to
patient care and clinical instruction in
medicine, he was honored on his 80th
birthday with the dedication of the David
K. Miller Wing of the Erie County Medical Center.
orman Chassin, MD , completed his
residency training with Miller in 1951
and remained a lifelong colleague and
friend. "Dr. Miller was not only a teacher,
but he was an example for us, " Chassin
says. "He was known as a counselor to
his trainees. I still see some
of these physicians at meetings and they tell me the
most important time they
spent in their professional
life was the three to five
years they spent with Dr.
Miller. "
"He was a tremendous
clinician who ran a very
tight ship and really challenged young people," Calkins recalls.
"He had a wonderful way with those he
trained and they, in turn, loved him
tenaciously. "
"The thing I remember most about
Dr. Miller," Chassin says, "is that, as a
teacher, he never stopped taking care of
patients. He never turned down a referral from a colleague. If you had a tough
case, you'd tell him you needed his help
and he was there, even if it meant making
a house call along with you. Sometimes
he'd add an important but subtle observation; other times, he just gave you and
the patient confidence by being there
because he was a giant in his field, and his
greatness touched the patients. " +
Amemorial service will be held for Or. Miller on
Friday, April 24, 1998, at 1 p.m. at the Bernard
Smith Amphitheater, Erie County Medical Center, in
conjunction with Spring Clinical Day.

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Noise-Induced Hearing Loss
Partially Rescued

sensory cells express a rush of glutathione, an antioxidant that absorbs
free radicals. R-PIA was found to increase the activity of glutathione, thus
oise-induced hearing loss may be providing enhanced protection from
caused partly by free-radical oxi- free-radical damage.
dative damage to sensory cells in
To test the effect of the drug on hearthe inner ear, and laboratory stud- ing loss, researchers applied R-PIA topiies of a drug called R-PIA have cally to the inner-ear membrane of one
shown that it can lessen the ex- group of animals and applied a saline
solution as a control in a
tent of damage by ensecond group. The anihancing antioxidant
activity, researchers at
mals then were exposed
to mid-frequency noise
the University at
for four hours at levels
Buffalo's Center for
high enough to cause
Hearing and Deafness
temporary deafness .
have found.
Donald Henderson,
The loss of hearing was
verified by monitoring
PhD, UB professor of
brain waves in the hearcommunicative disoring center in the cortex.
ders and sciences, says
The lack of brain activthe action of R-PIA
" IN THE FUTURE, WE MAY
likely would be similar
ity in response to normal
BE ABLE TO RESCUE THE
in the human ear. "In the
sound indicated complete
hearing loss.
HEARING LOSS OF
future, we may be able to
Brain-wave activity
rescue the hearing loss
PERSONS INADVERTENTLY
was measured again at one
of persons inadvertently
EXPOSED TO LARGE
day, four days, and 20 days
exposed to large amounts
AMOUNTS OF NOISE. "
following noise exposure.
of n'"'ic;e, such as those
Results showed that the
near an explosion, for
example, through the use of this drug. " animals treated with R-PIA recovered
Noise-induced hearing loss, a major their hearing faster and more completely
health problem in industrialized societ- than those treated with saline.
"The R-PIA-treated animals also
ies, is a primary research focus of UB's
Center for Hearing and Deafness, which showed less damage and loss of senHenderson codirects with fellow scientist sory cells than control animals,"
Henderson says. +
Richard]. Salvi, PhD.
The new study, conducted by
L 0
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B A K E R
Henderson and colleagues Sandra
Mcfadden, PhD, and Bo-Hua Hu, PhD,
along with Richard Kopke, PhD, of the
U.S. Army, documents the action of
R-PIA on noise-induced hearing loss in
chinchillas, a mammal with an auditory
husband-and-wife team of psychiarange similar to that of humans.
trists at the University at Buffalo
In earlier work, the researchers
has received a $2.6 million grant
showed that the stress of loud noises
from the National Institute ofMencauses an increase in free radicals in the
tal Health to conduct one of the
inner ear, which can damage or kill
first major population-based studsensory cells. To defend themselves,

Searching for Genes Linked
to Schizophrenia

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ies aimed at finding the gene or genes
that may be linked to schizophrenia.
Carlos N. Pato, MD, and Michele T.
Pato, MD, UB associate professors of
psychiatry, are principal and coprincipal
investigators, respectively, on the
project. They have been building the
project for seven years in the Azores, a
group of nine islands located off the
coast of Portugal that make up a Portuguese state and where most inhabitants
are descended from a few families.
"Psychosis is a complex syndrome, the
most common form of which is schizophrenia," Carlos Pato says. "In at least 20
percent of cases of schizophrenia, other
family members are also affected with
the illness, but genetics may play a role in
an even greater percentage. Our study
will try to determine how often the illness and a particular gene, or genes, are
seen together. If we can find the gene that
causes the illness and then find the product of that gene, we can begin to design
more effective treatment."
About one percent of the world's population is afflicted with schizophrenia, a
mental illness characterized by symptoms such as deterioration of personality, disordered thinking, delusions, hallucinations, paranoia or catatonia. The
main form of treatment is antipsychotic
drugs, which must be taken regularly
and continually to control symptoms.
The five-year study will be carried out
in the Azores and in a population group
on the Portuguese mainland. "The
Azores are ideal for a genetic analysis,"
Pato says, "because the country is small
and its population has been relatively
genetically isolated, with most inhabitants descended from a few families. The
Azores have a centralized health system, and all 10 psychiatrists on the
islands are collaborating on the project."
The researchers will look for genetic
links using a variety of approaches. "We
will select genetic markers and look at
how the markers behave in well families
compared to a family where the illness

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Why Are Blacks More Prone to

shows up several times ," Pato says.
"We'll look to see if illness and genetic
markers exist together, and we'll analyze genetic patterns from ill person to
cardiology researcher at the Uniill person. We'll develop a description
versity at Buffalo may have found
of each suspect gene and determine
one answer to the question of why
how often it occurs with illness. "
more blacks than whites have high
An important aspect of the study will
blood pressure.
be a Haplotype Relative Risk analysis.
The answer appears to lie in the
Using this approach , researchers will
way
the
lining of blood vessels , the
analyze the set of genes from a patient's
parents that were not passed on to that endothelium, responds to certain sigpatient, Pato explains. The noninherited nals telling it to dilate. Bong Hee Sung,
PhD, UB associate professor of mediset then acts as a control.
A field team is already in place in the cine, has shown that in some blacks,
Azores. The UB researchers travel there blood vessels didn't relax and widen as
frequently to maintain close ties with the they should in response to a normal
project. Meanwhile, they are setting up a blood-vessel dilator. Dilation of blood
genetics research program and labora- vessels is one of the body's natural
tory at UB that ultimately will be mechanisms for easing blood flow , thus
lowering prescapable of performing
sure.
genetic analyses of any
Sung prepotentially inheritable disthe
sen
ted
ease, the researchers say.
study
results
Both Carlos and Michele
recently at the
Pato hold adjunct appoint12th Internaments with the Center for
tional InterNeuroscience at the
disciplinar y
University of Coimbra in
Conference on
Portugal, which is collaboHypertension
rating on the project. Also
in Blacks in
involved are james L.
London.
Kennedy, MD , head of the
THE FINDING REIN ·
Why the blood
neurogenetics section at Clark
FORCES THE RELATION ·
vessels don't relax
Institute of Psychiatry, UniverSHIP BETWEEN
and widen as exsity of Toronto , who is a
pected remains unHYPERTENSION AND
coprincipal investigator, and
clear, Sung says.
Eric Lander, PhD , of the WhiteDIABETES , TWO
"Th ese are all
head/MIT Center for Genome
DISEASES THAT ARE
healthy
people, "
Research, who will perform a
MORE PREVALENT
she
adds.
"They
genome-wide scan and collaboAMONG BLACKS THAN
had
normal
glurate on all data analyses.
WHITES .
cose
and
cholesM. Helena Azevedo , MD , proterollevels, and are
fessor of psychiatry at the University of Coimbra, is the principal in- not obese.There was no apparent reavestigator for the Portuguese team, and son for them to have endothelium dysCarlos Paz Ferreira, MD , director of psy- function . Where this comes from , we
chiatry at Psychiatric HospitalS. Miguel, don't know . We can't really say what
the pathway is yet. "
Azores, is directing the fieldwork. +
Sung and colleagues studied the

High Blood Pressure Than Whites?

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blood-vessel response in a group of l2
healthy African-Americans and l l Caucasians, all of whom had normal blood
pressure. They also showed normal fasting cholesterol levels, glucose levels and
other parameters known to affect blood
pressure.
The researchers measured the diameter of a vein in the left hand of all
participants and then introduced the
vasoconstrictor norepinephrine into the
vein to cause it to narrow. Veins of
participants in both groups narrowed
similarly.
Insulin, a vasodilator that acts on the
endothelium in addition to regulating
blood glucose, was added to the norepinephrine, and the vein diameter was
measured again. Results showed that
veins remained narrowed in five , or 42
percent, of the l2 African-Americans,
indicating they did not respond normally to insulin as a vasodilator.
Sung says the blunted response may
be one of the mechanisms underlying
the increased prevalence of hypertension in some blacks. "This subgroup of
African-Americans was resistant to the
vasodilatory action of insulin. Nothing
happened to their blood pressure when
insulin was infused."
Sung said the finding reinforces the
relationship between hypertension and
diabetes , two diseases that are more
prevalent among blacks than whites.
Insulin resistance is a risk factor for
adult-onset, or type II , diabetes.
The question Sung and colleagues now
are trying to answer is why an apparently
healthy subgroup of blacks is not
responding normally to insulin. She said
the condition has important health consequences, and that once scientists know
what causes it, they can work to prevent it.
Additional researchers on the study
were Marilou Ching, MD; Surendra G.
Gudapati , MD ; and Michael F. Wilson , MD , all of the UB Department of
Medicine. +
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lesser-known functions include activating the immune system in response to
stress; it also plays a role in fertility.
It is another of prolactin's lesserUniversity at Buffalo neuroendo- known effects-its role in regulating
crinologist is providing new in- the seasonal molting cycle in such anisights into the cause of changes in mals as the Siberian hamster-thatdrives
blood levels of the hormone Badura's research. Siberian hamsters
prolactin, which plays a role in turn from brown to white in winter and
regulating many vital human experience a corresponding drop in prolactin levels. Badura is attempting to
physiological functions.
Supported by a grant from the Na- identify the brain chemical that triggers
tional Science Foundation (NSF), Lori this change. Once identified, the chemiBadura, PhD, assistant professor of psy- cal could be manipulated to correct an
chology, is attempting to identify the existing hormonal imbalance.
The Siberian hamster is a convenient
neurotransmitter that signals those
model
for studying prolactin regulation
changes. If successful, her research
could lead to interventions to keep the because its hormonal variation is photosensitive-triggered naturally by seasonal
hormone at optimum levels.
"Some medications-ones that in- changes in amount of daylight- and
crease dopamine, for example- requires no chemical manipulation.
"A number of faccan cause prolactin
tors
can affect prolevels to be low," she
lactin
release,"
says. "Too much or
Badurasays. "Ifthere
too little prolactin
are big changes, a
can cause infertility.
number of factors
It is important to
may be involved. At
know what neurothe basal level, the
chemicals are affectchanges
are small
ing any system
and
easier
to
because a change in
control."
one causes a change
One of the neusomewhere else.
rotransmitters
that
"We already know
"TOO MUCH OR TOO
Badura and colleagues
prolactin's effects, but we
are looking at is norepiLITTLE PROLACTIN CAN
don't know what causes
nephrine because its levthe brain to regulate its
CAUSE INFERTILITY.
els
also appear to change
production. If we can find
IT'S IMPORTANT TO
under
different light conthe chemical signals that
KNOW WHAT
ditions
and it is known
cause these changes, we
NEUROCHEMICAL$ ARE
to be involved in prolaccan design a drug to reguAFFECTING ANY SYSTEM
tin release.
late them. Knowing the
BECAUSE A CHANGE IN
"We don't know if this
chemical neurotransmitis coincidental, if other
ONE CAUSES A CHANGE
ters that underlie each
factors are involved or if
system would allow us to
SOMEWHERE ELSE. "
there is a real cause and
compensate for problems
effect,"
she says. "Once
in any of them."
we
establish
a
relationship,
we can maProlactin is perhaps best known as
the hormone responsible for stimulat- nipulate norepinephrine and see ifprolacing mammalian milk production. Its tin changes. No one has done that yet."

Study Seeks to Identify Brain
Chemical Regulating Prolactin

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Before Badura can move into that realm
ofdiscovery, however, she and her graduate students must master the delicate and
difficult technique of implanting the necessary microinstruments in the mousesized hamsters so that any physiological
changes can be measured. "If this technique becomes viable," she says, "it would
permit a new direction in research that is
very attractive to granting agencies. This
will allow us to document any kind of
physiological activity and physical state
minute by minute. We will be able to
answer many questions that we haven't
been able to answer before."
Badura's work has been funded by the
NSF since 1993, when she was a
postdoctoral fellow at the University of
Connecticut. +
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Link between Heart Disease
and Gum Disease
trange as it may seem, taking care
of your teeth and gums may also
protect your heart.
Funded by a $1.2 million grant
from the National Institutes of
Health, University at Buffalo dental researchers and preventive medicine specialists are beginning a fiveyear study of the relationship between
periodontal disease and heart attacks.
The study and the size of the award
reflect a growing interest in new evidence suggesting that infections in the
oral cavity may trigger disease elsewhere in the body.
UB dental researchers are in the
forefront of this field, with several preliminary studies showing that persons
with gum disease are at high risk of
developing heart disease.
The oral bacteria that cause gum
disease appear to be the culprit, says
Robert Genco, DDS, PhD, SUNY Dis-

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•

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••••

- ~~~~~~~~

HURWITZ &amp; FiNE, P.C.
[ATTORNEYS AT LAW

tinguished Professor, chair of the UB problems, eliminating the influence of
Department of Oral Biology and princi- other factors that contribute to heart
disease, such as smoking or obesity, to
pal investigator on the new study.
"Oral bacteria enter the bloodstream determine the extent to which gum
via small ulcers that develop in the gum disease is an independent risk factor
for heart disease in
tissue of persons with
both men and
periodontal disease.
women.
These bacteria conThe participants
tribute to plaque forwill
be followed to
mation and increase
determine the incithe chance of clots
dence of second
forming. Clots can
heart attacks among
also accumulate
the heart patients
around damaged tiswith and withou t
sue, such as a lesion
periodontal disease.
in the blood vessel or
Researchers also
a replaced heart valve.
will collect data on
These accumulations
UB DEN T AL
the number of first heart
can narrow blood vessels.
attacks
in a control
The bacteria also cause
RESEARC HERS ARE IN
group and assess their
platelets to aggregate and
THE F O REFRONT OF
can increase the chances
relationship to periof clots forming. Clots in a
odontal disease.
TH IS FI ELD, W ITH
If periodontal disease
narrowed blood vessel can
S E V E RAL PRE LIMINARY
is found to be a true risk
cause a myocardial infarcfactor for heart attack,
tion, or heart attack.
STUDI ES SHOWING
"We've known for
the next step will be to
THAT PERSONS WITH
find out if treating the
some time that oral bacteria can precipitate these
disease reduces that
GUM DISEASE ARE AT
kinds of reactions,"
risk, Genco says. BeHIGH RI S K OF
cause cardiovascular
Genco says. "We just redisease remains a leadcently put these findings
DEV ELOPING H E ART
ing cause of death in
together as a possible
most developed counexplanation of how
D I SEASE.
tries, the answer to that
bacteria that cause gum
question could have a
disease can also increase
major impact on public health.
the risk for heart disease. "
"Although we know much about the
The new study will involve 1,000
people who have survived a first heart risk factors for heart disease, there is
attack, and 2,250 people who have not still much unexplained risk to be ashad a heart attack. A complete health sessed," he notes.
Coinvestigators on the study are
history will be compiled on all particiMaurizio
Trevisan, MD, and Karen
pants, and all will be given a dental
exam with X-rays to determine the ex- Falkner, of the UB Department of Soistence and extent of periodontal dis- cial and Preventive Medicine; and Sara
ease. Blood samples also will be taken Grossi, DDS, Ernest Hausmann, DMD,
PhD ,Juan Loza, DDS, PhD, andjoseph
and cholesterol profiles determined.
Researchers then will analyze rates Zambon, DDS, PhD, all of the UB School
of periodontal disease among heart- of Dental Medicine. +
attack patients and those with no heart
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S ERVICING
T HE L EGAL
N EEDS OF THE
H EALTH S ciENCEs
CoMMUNITY
• Managed Care
• Purchase &amp; Sale of Practice
• Business &amp; Tax Planning
• HCFA Safe Harbor Regulations
and Physician Self-Referrals
• Contracts with Private
&amp; Public Entities

• Employee Relations
Counseling
• Fringe Benefit Programs
• Representation Before
Government Agencies on
Audit &amp; Business Issues
• Facility Finance
and Construction
• Credentialing
and By-Laws
• Hospital/Medical Staff Issues

Please contact
Robert P. Fine or
Lawrence Mo Ross
at 716-849-8900

1300 Liberty Building

Buffalo, New York

I

�~ -·······················································································

El
CLASS OF 1 958

Reunion Chairs Prepare for
Reunion Weekend Festivities

Allred M. Stein (pictured)
Dear Classmate-Fifty Eight-Can you believe it? Forty years since you became an MD.
Our reunion will take place on April 25. Save
the date. We have the place. We will celebrate.

Michael Genco

t's not too early to plan for the 1998 Spring
Clinical Day and Reunion Weekend. A cocktail reception will be held on Friday, April24,
1998. The 61st Spring Clinical Day andReunion Dinners will be on Saturday, April25. For
more information, call the Medical Alumni Association at (716)829-2778. The reunion classes
are of 1948, 1953, 1958, 1963, 1968, 1973,
1978, 1983, 1988, and 1993. Here's what your
reunion chair has to say to you!

Mickey Stein and l are putting together the
usual celebration. lt won't be the same unless
you are there!

CLASS OF 1 963

Anthony M. Foti
We traveled life's path together for a meaningful period. lt would be fun to see how we, the
school and Buffalo have changed in 35 years.
Please plan to attend our reunion. We hope to
see you there.

CLASS OF 1948
CLASS OF 1968

Harold l. Graff

Daniel J. Fahey

It's hard to believe that it has
been 50 years since graduation.
Please reserve Reunion Weekend of April 24-26. Hope everyone will be here.

Great expectations! Looking forward to renewed friendships of
the Class of '48.

Thomas J. (umbo

Robert A. Milch

Dear Classmates, lt's 30 years for
us. Please come back on April25
to celebrate and reminisce together.

We are all looking forward to
seeing you again for our 30th.

CLASS OF 1 973

CLASS OF 1953

Michael A. Sullivan

Arthur W. Mruczek (pidurec/)

Next April 25, imagine you're at our 45th
reunion. Like Marv Levy says, "Where would
you rather be than right here, right now?"

We are looking forward to seeing you at the
25th-Year Reunion Weekend. Please plan to
join your classmates for this special quarter
century of memories.

Michael A. Sansone
Come back to your roots for the 25th reunion.
We need you to make it a success!

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•

CLASS OF 1 988

CLASS OF 1978

Helen (Hess) and Andy
Cappuccino

David L. Marchetti
The clock is ticking! Our 20th reunion (our
"Distant Replay"). Please find the time to attend.

"Collagen Superstar";
"Insulin Superstar";
Who really ca res? Who
really remembers?
But memory of the parties will last forever.
Come celebrate lOyears
out of med school.
April25. Save the date!
CLASS OF 1 993

CLASS OF 1 983

Michael J. Aronico

Richard L. Collins

Dear Class of 1993, Can you believe it's been
five yea rs since med school graduation? Why
don't you book April 24 for our five-year
reunion weekend and Spring Clinical days.
Look forward to partying and catching up
with all of you .

Let's ge t together and have some fun at our
15th.

&amp;

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writes
from her home in Hillsdale,
NY: "At age 72 , I'm still working. Retired from my solo family practice after 35 years , but
the retirement didn't take , so
I'm doing school health. I'm
the medical director of Columbia and also of Green Counties'
outpatient Alcohol and Drug
IRMA M . WALDO , ' 49 ,

Treatment Services. And after
years of seeing young'uns and
their families , I now am seeing
the pathology of medical school
days , as an attending at the
Pine Haven Nursing Home for
40 of my dear little old folks!
John is retired , and we both ski
all winter. "

1

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0

5

JOHN J . LAMAR , JR ., '63 ,

retired in September 1997 after
30 years of solo pediatric practice. He now spends much of his
time visiting his grandchildren,
Garrett, age five , and Skyler, age
three, in Ft. Hood, TX.
IRA H I NDEN , '65 , says, "I'm
very pleased to announce that
the Wooster Clinic, a 31-physician multispecialty group, of
which I am a member, has
merged with the Cleveland
Clinic. I will continue to practice in the Family Practice Department of the Cleveland
Clinic's Division of Regional
Medical Services.

BARRY A . WEINSTE I N , ' 69 ,

has been elected to the Erie
County Legislature, representing
most of Amherst, NY. His twoyear term began January 1, 1998.
He continues in family practice
in Amherst, in his 24th year.

1

9

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5

V . SZEKERES , '71 ,

AGNES

writes , "I was selected Internist
of the Year" in 1997 in our Kaiser Facility in Bellflower, CA. I
was proud to be the only lady to
be honored by my colleagues
after six years of well-deserving
male internists. We have 65 internists in our group. "
of
Toledo , OH , has been honored
by the Vitreous Society, the
world's largest organization of
vitro-retinal surgeons , with a
named lecture in recognition of
his contributions to the society
and to the advancement of vi.treoretinal surgery. The "Founder's
Lecture" award wi.ll fund internationally renowned speakers
and support vision research for
the society, which Dr. Bovino
cofounded and of which he is
past president.
JERALD A . BOVINO , '71 ,

has
accepted a position as associate
professor in the Department of
Otolaryngology at Case Western Reserve School of Medicine
and Metro Health Medical Center in Cleveland, OH.
GREGORY ANTOINE , '76 ,

®

MELINDA AQU I NO , '92 ,

says ,

"I finished my pain management
fellowship at Montefiore Medical Center and joined the faculty
there as a full-time attending in
both anesthesiology and pain
management. I am currently
studying to become a licensed
acupuncturist to enhance my
pain management practice. "
KRISTINE TENEBRUSO , '93 ,

of Honeoye Falls, Y, and Todd
Blalock announce the birth of
their first baby, Lauren Marisa
Blalock, on July 14, 1997. Kristine
is an attending physician in emergency medicine at Rochester General Hospital, Rochester, NY.
of
ew Orleans , LA, has begun his
residency in ophthalmology at
the Ochner Medical Foundation
and Louisiana State University
Hospital in ew Orleans. "Ever
the boater," he writes, "I have
chosen to live and spend what
little free time I have on my 3 7foot sailboat, Yank ee."
THOMAS R . ELMER , '97 ,

OBITUARIES
COL.

HERBERT BERWALD ,

'27 , of Napa , CA , died on Octo-

JOHN R . ANDERSON , '67 ,

writes from DePew, NY: "I retired as medical director at
Brothers of Mercy Nursing and
Rehabilitation Center on December 31 , 1997."

1997. Mary writes, "Our son ,
Sam, is now two. Joe has joined
a group of otolaryngologists in
Bayshore, Y, after completing
a head and neck and microvascular surgery fellowship . I completed a fellowship in pediatric
infectious diseases and am in
private practice. "

1
MARY

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( CAPPUCCINO)

AND

BONAFEDE , ' 91 , announce the birth of their second child , Ella , on June 30,

JOE

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ber 10, 1997. Following graduation from UB, Dr. Berwald was
commissioned in the U.S. Army
and received his surgical training at Walter Reed General Hos-

p

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pita!. During World War II, he
was commanding officer of the
217th General Hospital in England and France , the largest
general hospital in the European
theater. Following the war, he
was chief of the surgical service
at Percy Jones General Hospital
in Battle Creek, MI , and at the
343rd General Hospital in Osaka,
Japan . During the Korean War,
he was surgical consultant to
the Republic of Korea , after
which he served as chief of the
Departm ent of Surgery at
Letterman General Hospital in
San Francisco, where he retired
from the Army in 1957. Following his military retirement, Dr.
Berwald became chief of surgery
at the Veterans Home in
Yountville, CA , retiring from the
state in 1972. He then joined
Kaiser Permanen te Medical
Group , retiring from medical
practice in 1982. He is survived
by his wife of 67 years, Victorine
Cherney Berwald; his daughter,
Arley Hulstrand, of Denton, TX;
and his son, Col. Herbert T.
Berwald,Jr. , of Fairfax, VA ; and
eight grandchildren and two
great-grandchildren.
PATR ICIA A . MEYER , '50 , died

on August 27 , 1997.
CARL LOUIS EVANS GRANT ,

'83 , chair of the medical staff at

Sheehan Memorial Hospital and
clinical instructor in medicine
at University at Buffalo School
of Medicine and Biomedical Sciences, died Sunday, October 5,
1997, after a brief illness. He was
46 . Born in Manhattan , Grant
attended Marist College and
completed his pre-med studies
at Harvard University prior to

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TAKE TWO ...
AND CALL ME IN THE
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earning his medical degree at UB.
In addition to Sheehan Memorial

rottd:

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Hospital, he practiced internal
medicine at Buffalo General Hos-

Millard Fillmore Hospital's Resident Physician Program 1950-52
and a former research staff physician of the Millard Research Insti-

pital and Erie County Medical
Center. In 1992, he received the
UB Biomedical Sciences Commendation for Teaching Excellence.

cochair of an International Study
on Toxic Inhalation Programs of
the National Toxic Inhalation

Surviving are his wife, the former
Lachele Clemons; four sons, Khori

Group, headquartered in Milwaukee, WI, and Cleveland, OH. At

ofBuffalo and CarlJr., Adrian and
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present, Dr. Cordasco is affiliated
with the St. Luke's Hospital Medical Center and affiliate clinical professor of medicine at Case Western Reserve University. He is also
an emeritus (retired) of the Cleveland Clinic Foundation and presently works in the Department of
uclear Medicine as a research
associate.

daughters, Christian of New
Britian, CT, Kahlia and Lauran, of
Buffalo; and Maria, LaShae and

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hysician

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�Planned Giving to UB.
A tax deduction and income lor life are

two of the benefits you may receive with

planned giving to the UB School of

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UNIVERSITY AT BUFFALO
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�BUFFALO PHYSICIAN

Volume 32 , Number 2
ASSOCIATE VICE
PRESIDENT FOR
UNIVERSITY SERVICES

Dr. Carole Sm1th Petro
DIRECTOR OF
PUBLICATIONS

Kathryn A. Sawner
EDITOR

Stephamc A. Unger
ART DIRECTOR/DESIGNER

Alan j. Kegler
ASSISTANT DESIGNER

Lynda Harmel
PRODUCTION MANAGER
Ann Raszmann Brown
STATE UNIVERSITY OF
NEW YORK AT BUFFALO
SCHOOL OF MEDICINE AND
BIOMEDICAL SCIENCES

Dr. John Wright, Interim Dean
EDITORIAL BOARD
Dr. Bertram Portm , Chair
Dr. Marun Brecher

Dr. Harold Brody
Dr. Linda j. Corder
Dr. Alan J. Dnnnan
Dr. James Kansk1
Dr. Barbara Maj eroni

Dr. Elizabeth Olmsted
Dr. Charles Paganelli
Dr. Stephen Spauldong
Dr. Bradley T. Truax
Roy Vongtama
Dr Franklin Zeplowitz
TEACHING HOSPITALS AND
LIAISONS

The Buffalo General Hospital
M1chael Shaw
The Children's Hosp1tal of Buffalo
Erie County Medical Center
Mercy Health System
Mollard Fillmore Health System
Frank Sava
Niagara Falls Me mona! Medical
Center
Roswell Park Cancer lnstnute
Sisters of Chanty Hosp1tal
Dennis McCanhy
Veterans AffaiTS Western ew Yo rk
Healthcare System
© The State Umversity of New York
at Buffalo

Buffalo Physi cian IS publi s h ed
quarterly by the State Umversity of
New York at Buffalo School of
Medicone and Biomedical Sciences
and th e Offoce of Publications. ll1s
sent, free of charge, toalumm , faculty ,
students, res1dents, and fnends . The
staff reserves the right to edn all copy
and submissiOns accept ed for

publication.

Dear Alumni and Friends,
of our major hospital affiliatesthe Children's Hospital of Buffalo, Buffalo General Health System and Millard
Fillmore Health System-is fast approaching. At the same time, the Catholic
Hospital System is moving toward a different and more integrated configuration,
and the U.S. DepartmentofVeterans Affairs Medical Center is being molded into
the evolving VA Integrated Network (VISN#2). Within this flurry of mergers
and reorganizations, the Erie County Medical Center is struggling to establish
its essential niche in this community's health-care delivery system, and Roswell
Park Cancer Institute is experiencing a "rebirth" of sorts. Not only will each of
these dynamics significantly change the nature of health care within the greater
Western ew York area but, as noted in previous Buffalo Physician messages, they also present a
variety of important challenges for the university and, in particular, for the School of Medicine and
Biomedical Sciences. My message in the last issue of Buffalo Physician outlined a few of these
challenges, and while we cannot report much externally visible progress, some progress has been
made, at least in terms of "establishing a direction" as distinct from "arriving at a destination. "
I am therefore particularly pleased to report that Dr. Michael Bernardino, from Emory University,
accepted the important position of vice president for health affairs and came "on board" Aprill , 1998. Dr.
Bernardino, an academic radiologist by training who is well versed in the ways of managed care and practice
plans, brings much-needed expertise to the university. The circumstances described above underscore the
wisdom of separating the dean of medicine function from that of the vice president for health affairs.
Although there will continue to be significant overlap in responsibility, each position is sufficiently
different in today's new world of changing education focus , research direction , practice configurations,
mergers and managed care that differing skill sets need to be employed-and applied on a full-time ,
concentrated basis. Mike's arrival should not only herald the development of a more coherent strategy for
the medical school-and for the other health science schools-in dealing with the rapidly changing
environment, it should also greatly increase the school's "negotiating strength. "
The interests of the community, in the broadest sense, represent those of the medical school and
of the larger university. Hopefully, your school can serve as a catalyst to bring some rationality to the
present turmoil.
In the meantime, it is clear that our destiny will be to work side by side, and in collaboration, with our
community physicians and volunteer faculty. The commitment is to be inclusive, not exclusive, and to
work with the various players in as collaborative a fashion as possible. It won't be easy, but I think you will
agree: It's the only logical way for us to go!
THE ANTICIPATED MERGER DATE FORTH REE

John R. Wright, MD
Interim Dean, School of Medicine and Biomedical Sciences

Dear Fellow Alumni,
lT S EEMS LIKE TH E SC HOOL YEAR IS FLY! G BY. I have the feeling that it just
began. However, here we are looking down the homestretch, with Match Day
(March 18) and Senior Reception (March 21) behind us, and Alumni Reunion
Weekend and Spring Clinical Day (April24-25) upon us. I hope that many of you
were/are able to join us for some of these activities.
We are happy to announce that Dr. Nancy Nielsen will be joining the Medical
Alumni Association Board of Governors. A past recipient of the prestigious Samuel
P. Capen Alumni Award, she currently holds the position of assistant dean for thirdand fourth-yearmedicalstudents. We look forward to her participation and counsel.
I wish to advise you that the Medical Alumni Association will no longer be
able to offer a joint membership with the general University at Buffalo Alumni Association. That
association has decided to solicit your membership separately. I will give a more detailed explanation
in the next issue of the Buffalo Physician.
Dr. john Bodkin has put together an excellent program on the "Aging American" for our Spring
Clinical Day, April 25. This year's recipient of the Stockton Kimball Memorial Award , Edward H.
Wagner, MD '65, MPH, will deliver a lecture at the annual Medical Alumni Association luncheon tha}
day. He is professor of medicine at the University of orth Carolina and at the Umversny o
Washington , and also director of the W. A. MacColl Institute for Health Care Innovation, in Seattle.
I am looking forward to seeing you at the Alumni Weekend and Spring Clinical Day.
With warm regards,

~B"~~.M~~

President, Medical Alumni Association

m.o,

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VOLUME

32 ,

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NUMBER

2

SPRING

The Sounds
of Science

Focusing AUention
on ADHD

Northern
Exposure

RESEARCHERS FIND

COMPREHENSIVE

A

SloE IN BRAIN

APPROACH

TAKES LEAVE OF

RESPONSIBLE

TO TREATMENT

ABSENCE TO

FOR TINNITUS

by S. A. Unger

WORK IN ALASKA

1998

MEDICAL STUDENT

by Bretton Newman

by S. A. Unger
photos by K.C. Kratt

1
U 8

ALUM THRIVES

IN THE BIOTECH

INDUSTRY

by Betsy Sawyer

1

FDA APPROVES

NEW DRUG FOR

2
3

1

COLLABORATIVE
EFFORT WITH

PRESIDENT

UB,

THE UNIVERSITY AT

NAMED FOR

ALBANY AND

HEALTH AFFAIRS

ROSWELL PARK

by Arthur Page

by Jessica Ancker

Research ews

Cl

tP.

FOUR U 8

A udent's pe spec ive:
THE BEGINNING

TREATMENT OF

OF MY QUEST

LUNG CANCER

by Pamela Crowell

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ALUMNI

PRESENTED AMA

LEADERSHIP AWARD

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RESEARCHERS FIND SITE IN BRAIN RESPONSIBLE FOR TINNITUS
ICHAEL D EAKI

RECALLS the

exact moment in his life when he first experienced tinnitus, the constant ringing in the ears
that affects an estimated 50 million Americans. "I remember waking up on the morning
of Aprill2, 1994, with a high-pitched squealing in my ears. I thought the microwave was
going off downstairs but I wasn't able to find
the sound anywhere," he says.
Recently,
For many people who experience tinnitus, the condition represents a nag- Deakin found
ging bother in their lives, but one they something else
manage to cope with reasonably well. to keep him
For others, however, like Deakin, tinni- going: the retus is a debilitating condition because it sults of a study
affects them emotionally, to an extent published in
Using positron emission tomography, Alan Lockwood, MD, (/eft}, and Richard Salvi, PhD, have
that their lives are severely disrupted. "I the january
localized the spontaneous neural activity associated with tinnitus to the brain's temporal lobe.
went into a state of depression and wasn't 1998 issue of
Neurology in which researcheven able to work," says the
"Tinnitus will affect 30 to 40 percent
ers using positron emission of all people by the time they reach age
56-year-old CPA and BufB y
falo businessman. "I have
tomography (PET) have for 60, and these numbers are expected to
S . A
spent the past four years
the first time pinpointed the increase as the baby-boomer population
looking for help, but I've
specific regions of the brain ages," lockwood says. "People with seU N G E R
been told this is something l
responsible for tinnitus.The vere tinnitus, which is currently about 10
will have to learn to live with
study was conducted at the percent of elderly Americans, often sufbecause there is no known treatment.
University at Buffalo School of Medicine fer depression, anxiety, sleep disruption
"l have friends and know people who and Biomedical Sciences and the U.S. and other symptoms that have a major
have tinnitus, and they're not that dis- Department of Veterans Affairs Medical impact on their quality of life. Without
tressed by it, but for me, it has seriously Center in Buffalo by lead researchers objective information on how and where
affected my life. I can't read, and I can't do Alan Lockwood , MD , and Richard the condition originates, developing efmuch that involves significant concen- Salvi, PhD, who have since received a fective treatments has been difficult. By
tration. I have good days and I have bad $1.5 million grant from the IH to identifying the sites in the brain that
days; what keeps me going is knowing conduct a major investigation of tinnitus mediate tinnitus, we have taken a critical
that I will have some good days. "
and hearing loss using PET scanning.
step down the road toward a cure

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TINNITUS

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for this disabling condition. "
Lockwood, a professor of neurology,
nuclear medicine and communicative
disorders and sciences at UB , is director
of the Center for Positron Emission
Tomography at the Buffalo VA medical
center, a joint venture with UB , where
the research was conducted. He and
Salvi, who is codirector of the UB Center
for Hearing and Deafness, studied tinnitus patients who have the unusual ability to control the loudness of the ringing
by clenching their jaws.
"We went to a tinnitus support group
here in Buffalo," Salvi recounts, "and
during conversations with the participants, we learned that some of them
could modulate their tinnitus: They could
make it louder or quieter by pressing or
touching their face around the mouth or
jaw, clenching their teeth or sometimes
pressing on a tooth. This was a real
breakthrough in the project because it
meant we could look at the brain in two
different states: when the tinnitus was at
its normal level and when it was louder
or quieter. We used this quite effectively
to design the brain-imaging study."
The study involved four tinnitus patients, all of whom had mild to severe
hearing loss, and six persons with normal hearing and no tinnitus who served
as controls. All participants took standard hearing tests before the PET scanning began. By working with these participants , the researchers were able to
track fluctuations in cerebral blood flow
through PET scans taken while the patients manipulated their symptoms, creating a map of the brain site responsible
for tinnitus activity. "We have four major
findings in this study," Lockwood says.
"The most important is that we were able
to localize the spontaneous neural activity associated with tinnitus to the temporal lobe of the brain, which is the most
important auditory region of the brain. "
The researchers then included another step in the design of their study:
They compared the phantom sounds of
tinnitus with activity that was produced
in the brain by real sounds. In so doing ,
they narrowed down the population of
patients in the study to include only

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those people who experienced tinnitus
in one ear-and what they found was
that most had tinnitus only in their right
ear. lt was these two factors-the unilateral expression of the phenomenon
and the ability to control the loudness
by a voluntary means-Lockwood says,
that enabled the researchers to next
compare the brain region associated with
spontaneous neural activity of tinnitus
in the right ear only, with the brain
regions activated by playing a real sound
in the ear.

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hat we found was that the
real sounds caused bilateral neural activity, whereas the phantom sounds of
tinnitu~ were associated with unilateral

"TINNITUS WILL AFFECT

30

THE TIME THEY REACH AGE

TO

the limbic system, the part of the brain
that, among other things, controls emotion. "Our third finding, therefore, was
that in tinnitus patients, but not in normal controls, there is this crossover between the auditory system and the limbic system. We now think this is the
pathway through which the phantom
sounds are conveyed that impact adversely on emotions," Lockwood says.
"An important aspect of the clinical
manifestation of tinnitus is that it's extraordinarily distressing to many people,
and we think this aberrant link between
the auditory and the limbic systems is
the means by which this information
gets transferred. "
The fourth finding of the study resulted from a strategy whereby the re-

40

PERCENT OF ALL PEOPLE BY

60, AND THESE NUMBERS ARE

EXPECTED TO INCREASE AS THE BABY-BOOMER POPULATION
AGES," LOCKWOOD SAYS.

activity," says Salvi. "This told us several important things , the most important of which is that the source of this
neural activity had to be in the brain.
The unilateral delivery of sound to just
one ear activates just one cochlea. And
if the cochlea had been the site of the
spontaneous neural activity that causes
tinnitus, we would have seen bilateral
activation just as we saw when we played
real sounds. So this comparison between
phantom sounds and real sounds enabled us to arrive at our second major
finding , which was to localize the source
of the phantom sounds to the brain,
instead of the cochlea, where many investigators have believed tinnitus was
originating. "
Through comparison of this sound
activation in the patients, the researchers made two further significant observations. By playing the sounds into the
ears of the patients who also had sensory neural hearing loss , they found
activation of the hippocampus region of

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searchers subtracted the areas of activation caused by real sounds in the controls from the areas of activation caused
by real sounds in tinnitus patients. What
they found was that there is a much
larger area of the brain activated in tinnitus patients than in the control group.
"This finding indicates that the circuitry
of the auditory system has been changed
in some way in the patients with tinnitus, " Salvi notes. "It's much larger than
in the controls, and we think that's important because we surmise that some
of these new connections are the ones
responsible for causing the phantomsound sensations. "
According to Lockwood and Salvi,
other studies have been conducted using functional imaging techniques , such
as MRl, in which results have clearly
shown that the distress of phantomlimb sensation is associated with the
degree to which the brain manifests this
TINNITUS CONTINUED ON PAGE

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�William E. Pelham, Jr, PhD, working with a young participant in the Summer Treatment Program.

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Focusio Atteotion on
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TTE TION DEFICIT HYPERACTIVITY DISORDER (ADHD) is the most commonly diagnosed
disorder of childhood. Boys and girls with classic symptoms of ADHD have diffi.culty with attention,
impulse control and modulation of activity levels.
In recent years, ADHD and its prescribed treatments have swept into the medta spotlight, grabbing
the attention of the public with a fervor unrivaled at times by even the most hyperactive of children.
At the heart of this national discourse are questions about the number of children being diagnosed
with ADHD and the drugs with which they are being medicated-most notably Ritalin, a central
nervous system (CNS) stimulant less well known by its generic name methylphenidate.

'

At the University at Buffalo, William
E. Pelham Jr., PhD, one of the leading
ADHD researchers in the United States,
is conducting ongoing studies on how
best to manage this disorder through a
combination of behavioral modification
techniques and medication. As a result of
his studies and the innovative treatment
programs he has developed over the past
two decades, Pelham has gained widespread recognition as a researcher who
has helped to bring rigorous scientific
inquiry to bear on many of the con troverB

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siessurrounding the treatment of ADHD.
Recently, he was selected as one of a
handful of experts to plan and address a
~ational Institutes of Health Consensus
Statement Conference on ADHD, to be
held in November 1998.
CLINICAL TRIALS AIMED AT IMPROVING
MEDICATION CoMPLIANCE

Medication compliance problems severely
hamper treatment of children withADHD,
in large part because there currently is no
effective long-acting medication available
for treatment of the disorder. Ritalin, for
example, which has long been considered
the "gold standard" for ADHD medicaB

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tion, lasts only three and a half to four
hours so must be given three times a day
if it is to be effective.
"The schools are then faced with the
dilemma of how to give medications to
these kids and since there are fewer and
fewer school nurses, most schools don't
have a person to do that," explains Pelham,
who came to UBin 1996asa professor and
director of clinical training in the DepartmentofPsychology. "As a result, teachers,
secretaries, principals and guidance counselors-people who have lots of other
things going on in their workdays-are
trying to give the kids their medications
during school hours. And some schools
are so averse to this that they don't prompt
the child, which causes further compliance problems because kids with ADHD
have difficulty with organization in the
first place, so they don't remember to take
their medication."
Currently, Pelham is working with
coinvestigators at UB's School of Medicine and Biomedical Sciences to conduct
two clinical trials, the goals of which are to
examine drug delivery systems that would
overcome the need for children to take
ADHD medications more than once a day.
In the first trial, Pelham has received
$1.5 million from ALZA Corp. to study
the effectiveness of a 12-hour formulation

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of methylphenidate (Ritalin). His
coinvestigators on the study are Martin
Hoffman, MD, clinical associate professor, and Thomas Lock, MD, assistant professor of clinical pediatrics, in the Department of Pediatrics; and Eugene Morse,
professor and chair, Department of Pharmacy Practice, UB School of Pharmacy.
In the study, which will conclude
in mid-May, participants must already
be receiving methylphenidate and responding well to it. Once enrolled,
they are randomly assigned to either
continuing their normal Ritalin regimen, taking a comparable dose of the
new long-acting formula or taking a
placebo for one week each in a threeweek period, during which time their
regular classroom teachers and their
parents rate their behavior. Each Saturday they come to UB and spend the
day in a laboratory classroom, participating in recreational activities,
schoolwork and meals. Throughout
the day, their behavior is observed and
measured by researchers viewing them
from behind a one-way window and
by the teachers in the classroom, with
the objective being to track the onset
and offset of the medication.
"We are measuring the things that
you want to know Ritalin affects,"

0

�Pelham explains. "For example, in the
classroom, we want to see how the drug
affects their academic work. So we have
them spend lO minutes doing a timed
math or reading test and we track their
behavior while they work. "
Prior to the start of the study, all the
families receive psychosocial therapy.
Parents attend six training sessions to
learn about appropriate behavioral intervention techniques , and the children's
teachers attend four similar sessions
geared toward classroom interventions.
nee this small, tightly controlled study is completed, a second trial with
this same design will be
conducted by researchers
at the University of California at Irvine. Then, in September 1998,
UB and 10 other sites across the nation
will participate in a large-scale randomized Phase III study of the new longacting version of the drug. Children are
currently being accrued for this trial,
which will last a year.
In a second drug trial, Pelham has
received $250,000 from Bristol-Myers
Squibb to study the effectiveness of a 24hour skin-patch version of the drug
Buspar, an antianxiety agent that has
been used for years with adults. His
coinvestigators on this study are Helen
Aronoff, MD, assistant professor of clinical psychiatry, and Michelle Pato, MD,
associate professor of psychiatry, Department of Psychiatry.
"Bus par, while not a CNS stimulant, is
a drug that preliminary trials show may be
efficacious for children who do not respond to Ritalin," Pelham explains. In this
multisite trial, the participants-who cannot currently be taking any medication for
ADHD-are assigned either a placebo or a
lower or higher dose of Buspar in the
patch form, which they take for six weeks.
The children come to UB once a week to
be checked by physicians and research
associates; at the end of six weeks their
teachers rate their behavior using the
Conners Rating Scale. "At the end of the
trial, if the doctors think the child is doing
well, he is entered into the longer-term
safety phase of the study," Pelham says.

SUMMER TREATMENT PROGRAM
FocusEs oN BEHAVIOR WITH PEERs

Pelham's research into ADHD extends
beyond drug intervention to include behavior modification, as well. A disadvantage to giving Ritalin is that when children with ADHD stop taking the drug,
they revert to former patterns of behavior, and research shows many people
affected by this disorder do stop taking
the drug when they become teenagers or
young adults. "We know that medication, when stopped, has no long-term
effect," he says. "Furthermore, research
over the past few years suggests that by
combining medication and behavioral
treatments, significant incremental benefits are gained beyond either treatment
alone. Therefore, it's this combined approach that's becoming the treatment of
choice for ADHD. "
To that end, Pelham
has worked since 1980
to develop a Summer
Treatment Program that
integrates behavior
modification therapy
with activities normally
associated with summer
camp. Last summer, the
program accommodated
36 children, ages 7 to
12, who stayed together
for eight weeks, from
8 a.m. to 5 p.m. each
day. The program will
be offered at UB again in
the summer of 1998.
•
The activities are
largely sports-oriented
and provide a highly interactive setting in
which behavior problems can easily arise, especially those that pertain to peer relationships, a key area of focus for ADHD researchers. "Negative perception by childhood peers
is the single best predictor of adult maladjustment," says Pelham. "This is something we've known in the field of child
psychology for years. And surveys show
that children with ADHD are often uni-

formly disliked by their peers. "
Despite knowing that this problem is
predictive of poor outcomes in a whole
host of measures in children withADHD,
researchers have been frustrated in their
attempts to find treatment approaches
that have proven successful in managing peer relationship difficulties. "Peer
relationships are very resistant to
change," Pelham says, "and one of the
reasons why there has been failure is
that it's difficult to work on peer relationships in the office or the classroom,
the two locations where standard outpatient treatments are provided. " Overcoming the limitations of these traditional treatment venues is a key objective of the Summer Treatment Program.
Another limitation to existing interventions that the program is structured
to overcome is the fact
that although children
are more available for
mental health services
during the summer
months than they are
during the school year,
most mental health centers and professionals
cut back on or eliminate services for children with ADHD during the summer. "A
child with ADHD
spends as much time
awake and interacting
with others during the
summer months as he
or she does in school
during the entire rest of
the year ," Pelham
notes, "yet treatment
programs for most children with ADHD are
suspended during this
time, leaving the kids
to engage in what are
often unstructured acttvttles. Summers ,
therefore, represent an
untapped time for treatment."
In the Summer Treatment Program,
children are placed in age-matched
groups of l2 children, and treatments are
implemented by teams of five clinical

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staff members who are student interns.
Key behavior modification goals of the
program pertain to improving the
children's social interactions, academic
performance and self-esteem, as well as
increasing their ability to follow directions and complete tasks.
The children
spend three hours
a day in classroom
sessions conducted
by special education teachers and
aides, who use
behavioral modification techniques designed to treat the
children's problems in a classroom
context. Of these three sessions, one is
modeled after an academic special
education classroom, a second involves
computer-assisted instruction and a
third, art therapy. The remainder of the
day consists of recreationally based
group activities.
Treatment throughout the program
also includes teaching the children social skills necessary for them to function
effectively with their peers in a group
setting. These skills are introduced in
10-minute sessions that include role
modeling, instruction and practice, after which they are reinforced through
the assignment of group tasks designed
to promote cooperation.
In addition to social skills, an important aspect of peer relationships is a
child's performance in group recreational activities, according to Pelham.
"In the program, therefore, we strongly
emphasize teaching sports skills and
knowledge as a way to improve the
children's status among their peers and
to also improve their own self-esteem."
A major component of the program's
interventional goals takes the form of a
"report card" that is given to the children each day. Points are awarded for
appropriate behavior, such as listening
and paying attention, following the
rules and showing good sportsmanship, or subtracted for inappropriate
behavior, such as talking out of turn,
aggressiveness, not staying in line and
swearing. The children exchange their
points for daily and weekly privileges,

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social honors and home-based rewards.
If the standard interventions provided
by the program are insufficient or inappropriate, clinical staff members develop
individualized strategies to deal more effectively with a child's behavior. To ensure that what the children learn transfers

to their time outside the program, parents
receive training one evening a week in
how to implement behavioral modification techniques at home, a strategy Pelham
says is key to the success of the program.
ased on a variety of measuresfrom parent, counselor and
teacher improvement ratings,
to child self-perception ratings- the Summer Treatment Program has proven to
be a very promising form of treatment.
In recent years the program has been
replicated by the Departments of Psychiatry in the medical schools at Emory
University, Case Western Reserve and
New York University, as well as by the
Department of Pediatrics in the medical
school at Vanderbilt University. In addition, the program was adopted as the
child-based treatment component of the
psychological treatment arms in the National Institute of Mental Health's
(NIMH) Multimodal Treatment clinical
trial for ADHD and was implemented at
seven national medical centers as a part
of that trial.
However, because treatment programs-even those as intensive at the
Summer Treatment Program-have not
been shown to have long-term effects
without appropriate follow-up, Pelham
has developed a Saturday Treatment Program, booster parent training and school
interventions.
The Saturday Treatment Program,
which takes place each Saturday from
September to May, places an emphasis
on maintenance and generalization

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of behavior modification. Booster parent training consists of biweekly or
monthly sessions to help parents learn
how to communicate with their
children's teachers and how to continue
working on home-based programs. In
follow-up interventions, program therapists work with
teachers to help
them develop detailed classroom
management
strategies that will
provide effective,
consistent intervention for children with ADHD.
CLINICAL TREATMENT SETTINGS PRO•
VIDE BASE FOR ONGOING RESEARCH

In addition to providing effective treatment and training, both the Summer
Treatment Program and the Saturday
Treatment Program are designed to facilitate ongoing clinical research. Over
the years, Pelham and his coinvestigators
have conducted numerous double-blind,
placebo-controlled evaluations of stimulant medications within both these settings. For example, he and his colleagues
published a paper in 1990 in Pediatrics
(1990. 86, 226-37) in which they described the first study ever done to compare the efficacy oflong-acting drugs for
ADHD, including standard methylphenidate, sustained-release methylphenidate,
sustained-release dextroamphetamine,
and pemoline. "This study resulted in an
increase in the number of people using
long-acting stimulants because it showed
that they all work about as well as Ritalin,"
says Pelham. "So, despite the fact that
there are problems with these drugs, this
research showed that they are viable medications, worth using and worth further
development for treatment of ADHD. "
In another study done in the context
of the Summer Treatment Program,
Pelham looked at the controversial question of whether Ritalin gives children a
sense that they need the drug to solve
their problems. In this NIMH-funded
study- the first balanced-placebo design
study ever done in children-the
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Breech babies, blueberries and icebergs
TWAS NEARING MIDNIGHT ,

IT WAS GOING TO SHAPE ME
IN A WAY :-.:0 OTHER PLACE HAD BEFORE.

--

�U

ays later, on August 17, 1997, I began my descent
who had been authorized to fly into Nome (by a physician via
through thick, gray clouds on an Alaskan Airradio call). She had been thrown from her four-wheeler while
lines flight. Having made the decision to take a
moose hunting and was medically stable, except that her nose
leave of absence from my fourth year of medical
was lacerated and separated from her face. It was my job to
school at the University at Buffalo, I was ready to
stitch it back into place. At home, I thought, a plastic surgeon
begin a two-monthstayinNome, working alongwould have been called. Here, I was the person available to do
side local physicians and other health-care providers.
the job and I went to work.
Nome, population 4,500,
is situated on the isolated coast
of the Bering Sea in the northwest region of Alaska, some
161 miles from Siberia, and is
not connected by roads to any
outside community. Completely surrounded by water
or stretches of unpopulated
land in every direction, the
region boasts a history rich in
Inupiaq and Yupik Eskimo tradition, as well as a Caucasian
LEFT TO RIGHT· MOTHER HOLDING BABY
influence that has persisted since whaling times.
Every fourth
DELIVERED BY NEWMAN; RESPECTED VILLAGE
orne is also famed for its 1899 gold rush and
night, I took inas the terminus for the annualiditarod dogsled ELDER IN NOME FOR A CHECKUP YOUNG BOY FOR house call at the
race, held in March, which traverses 1,049 WHOM NEWMAN PERFORMED A SCHOOL PHYSICAL.
hospital. After
miles offrozen tundra from Anchorage toN orne.
6 p.m. there were
I arrived in orne in a drenching downpour and was told that
no physicians on duty at the hospital (they were on call from
it had been raining for weeks and would likely continue to for
home). I took the calls first and had the incredible opportumany more days. The unpaved streets ran thick with mud in
nity to see patients in the ER with no residents or attendings
front of small, colorful, boxy houses sitting on gravel plots with
present to direct me. When I needed help , I called for it, but
sparse lawns. This place was very different from any I had ever
in the meantime I learned to trust myself, to be calm and to
seen before, with severely limited opportunities for dining,
think about medical problems on my own for the first time.
entertainment or shopping. The focus instead is on the landAfter a few weeks in orne I had the opportunity to fly via
the berries in season, the whales and walrus, the salmon runs,
bush plane to the tiny Eskimo village of Unalakleet, for a
the hours of daylight, the whereabouts of the moose, and the
"village visit" with a doctor to see patients who had been
simple richness and variety afforded by the changing seasons.
waiting for months for medical attention (unless it's an
The Seward Peninsula, the great landmass supporting Nome
emergency, patients wait for a doctor to visit their village) .
and the many smaller surrounding villages, provides a natural
The villages are primitive when compared to Nome. Many
subsistence harvest rich enough to feed and fully support its
residents do not have running water in their homes, and there
limited human population. A mixed economy has taken hold,
is usually only one store to supply all needs. The schools are
split between the influences of "the lower 48" (which has gained
well built, and the homes are small and winter-tight. Life here
entrance via the telephone, satellite TV and the Internet) and the
is even less dollar-driven; instead, it is highly focused on the
ever-present, inescapable influence of the bountiful land.
hard work of "subsistence living," earning a living from the
The town of Nome is the most developed community for
land. I treasure memories of the days I walked out into the
miles around, and it is clearly the center of medical progress on
tundra to pick fat blueberries until my hands were purple
the Seward Peninsula. The hospital houses a 21-bed inpatient
with the delicious juices. I would return home with a full sack
unit, an outpatient clinic and a two-bed emergency room. Norne
and can berries as jam, bake fresh pies, and store the juices for
provides health care for its own population and for an additional
pancake syrup. The pride I felt in collecting my own food was
population of 5,000 spread throughout 17 rural villages, accespowerful, and I was blessed to share this experience many
sible only by bush plane or boat (the health-care region encomtimes over, thanks to the incredible generosity of those I met.
passes an area of some 23,000 square miles). Since the populaOne such kind and generous Eskimo woman was a "health
tion is not large enough to support full-time specialty medicine,
aide" at the Euksavik Health Clinic in the Unalakleet Village.
the physicians who reside in Nome practice as family physiShe invited me and the doctor I was accompanying into her
cians. The doctors in this remote area must each be willing and
home for dinner with her family, and we shared a "subsistence
able to handle the full gamut of medical problems.
meal" consisting of a fresh-picked salad from her garden,
My first week at the hospital was a busy one. On my first day
newly caught salmon from a nearby river, and home-baked
I was asked to see a young girl from one of the outlying villages
bread served with home-jarred jams. Our hostess , who was

10

�: EXPOSURE
raised in the village and is intimately familiar with traditional
village life and subsistence living, has taken classes to achieve
a minimal level of medical training approximately equivalent
to that of an EMT in the lower 48 states. With very little formal
training, these brave health aides, as they are called, are
responsible for managing the health needs of the entire
community: They coordinate prenatal OB care, complete
such procedures as blood draws and preventive pap smears,

deliver a healthy baby after cutting a fourth-degree episiotomy.
This was not the optimal situation: This young woman, who
was late in her pregnancy and had had minimal prenatal care,
had arrived in Nome on a village Oight that same day. She
presented to the clinic in active labor, and at that point our
choices were few. We did what we had to do to deliver that
baby-and we spent all night repairing that episiotomy.
The very next day another woman 35 weeks pregnant with

She had been thrown from her four-wheeler while
moose hunting and was medically stable, except that
her nose was lacerated and separated from her face.
It was my job to stitch it back into place.
twins was "authorized in" to orne from a village. When she
and then radio-call the physicians in Nome with accurate,
arrived, we found her four centimeters dilated and opted to
pertinent information regarding their patients, on whom they
medivac her to Anchorage (500 miles and a few hours by
keep updated medical records.
medically equipped bush plane). It was clear that this situation
This arrangement, unique to Alaska, of health aides procalled for a medivac; however, not all tough situations warviding first-line care to villagers and physicians backing them
ranted such an expensive Oight, and we were often faced with
up by radio-call from a hub, is important because it allows the
difficult decisions about the limits of what we could and could
health care of the village to be ministered to by members of
not handle safely in Nome.
the community. If an emergency arises that is beyond the
The system of health care on the Seward Peninsula
abilities of the health aides, then a "medivac" is called and the
is a fantastic endeavor dictated very much by the expanse
patient is retrieved by plane and Oown to orne for care. The
and challenge of the land. The isolation between villages is
health aides I met are a true inspiration. They embody an
extreme, as is the isolation between Nome and Anchorage,
institution that has grown out of the special needs arising
which adds yet another significant obstacle. I was touched
from Alaska's isolation.
by the ability of the health aides to take such an active role
I returned to orne at an extremely busy time to realize
in the care of their community members , and by the
that, although health care in Nome was more sophisticated
willingness of doctors to give up some autonomy to
than village health care, there were still many patients for
allow the Alaskan h ealth-care
whom we were not able to provide
system to exist as it does.
appropriate care. For example, at GOLOVIN, A TRADITIONAL ESKIMO VILLAGE ON
I was amazed and moved by the
THE BERING SEA VISITED BY NEWMAN.
orne's hospital, the Norton Sound
effect the land had on evRegional Hospital, we had
ery aspect oflife in Alaska,
a fully-stocked pharmacy,
from the gathering of food,
an X-ray department with
to the establishment of
sonogram,and a laboratory;
communities, to the prachowever, we had no CT,
tice of medicine. I wish all
no official OR and inadof
us could know the
equate space for certain
and beauty of napower
procedures or emergencies.
on
a daily basis as I
ture
Late one night I was
did
for
a
while
in Alaskacalled in from my stuexperiencing the strength
dent apartment in orne
of character that is built in
because one of my favorstocking a freezer for winite family doctors found
ter with salmon, moose
himself in the challengand in letting the land
meat
and
hand-gathered
blueberries,
ing position of delivering a footling breech baby. I had
+
shape
who
we
are.
never seen such a thing, because at home this presentation
would have gone to an obstetrician for a cesarean delivery.
Bretton Newman returned to the University at Buffalo School of Medicine a nd
Biomedica l Sciences in january 1998 and expects to graduate in May 1999.
In time, however, my fri end managed to su ccessfully
II

�Merging Medicine with Business
UB ALUMNUS CRAIG SMITH THRIVES N THE B OTECH OLOG

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DUSTRY

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MD the journey from medical school graduate
to founder and leader of a promising new biopharmaceutical company was not as great a leap as one might imagine. In fact, Smith says,
his career path has consisted of a progressive series of steps , "each
one logically leading to the next and not at all hard to take. "
Smith-who spent 16 years
junior faculty position there
in academic medicine before
as an instructor and assistant
B y
chief of service in the Departstepping into the corporate
B E T S Y
world-is president and CEO
ment of Medicine. He was
SAWYER
of Guilford Pharmaceuticals,
subsequently invited to stay
a company he established in
on as a faculty member at the
university and became an
1993 to discover and develop
drugs for the diagnosis, treatment and assistant professor in medicine in 1976.
Along the way, Smith says, "I found
prevention of brain cancer and other
neurological diseases. From his current myself consistently drawn to issues surrounding drugs and
vantage point as the
therapeutics. Early in
leader of a pacesetting
my career I won a
pharmaceutical busiGUADEL Wafer
(polileprosan 20 w1th
fellowship that allowed
ness, he looks back on
carmustine implant)
me to complete a yearan unusual and rewardlong sabbatical at the
ing career, first in
Qohns Hopkins] School
academic medicine and
Public Health and
of
then in business.
Hygiene
, studying
Born and reared in Orchard Park, New York,
epidemiology and
Smith graduated from
statistics, and I
Nichols School in
became interested in
Buffalo in 1964. He
applying the principles
left the area briefly to
I learned in those
complete undergradufields to the study
ate studies in biology at
of new drugs."
The University of the South in
Smith was also beginSewanee, Tenning to realize
The GLIADEL®wafer, for treatment of brain cancer.
nessee, and then
that he had talreturned in 1968
ent as an orgato attend medical school at the Univer- nizer, as well as a flare for building
sity at Buffalo School of Medicine and programs and inspiring teamwork. "I've
Biomedical Sciences.
always gotten enjoyment from the
Followinggraduationfrom UBin 1972, process of doing things that perhaps
Smith completed an internship and resi- aren't popular, but that are important
dency atjohns Hopkins University School for the achievement of a valuable goal ,"
of Medicine and, in 1975, was offered a he says. "I believe that more is

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accomplished when people work
together toward a common purpose ."

It was atjohns Hopkins in the mid-1970s
that Smith first tasted the satisfaction that
comes from building an organization from
scratch. Under his direction, the Division
of General Internal Medicine grew from a
one-man operation-with Smith as its
sole member-to the third largest division in the Department of Medicine in
terms of National Institutes of Health
(NIH) funding, patient care revenues and
teaching responsibilities.
In 1985, with funding from the
Burroughs-Wellcome Foundation ,
Smith was able to begin his second major building effort-the development of
a research program devoted to the thenfledgling field of pharmacoepidemiology. Under his guidance, the program
grew to include an interdisciplinary team
of two MDs , one PhD epidemiologist
and four support staff. Through the program, which still exists atjohns Hopkins,
clinical research projects were funded
by the Food and Drug Administration
(FDA) , the NIH and numerous pharmaceutical companies.
In 1988, Smith was courted and eventually hired by Centocor, a biotechnology company in Pennsylvania. As vice
president, he led the company's worldwide clinical research programs, initially directing a staff of 24. By 1992 he
administered a budget of $30 million,
oversaw more than 50 active clinical
protocols and supervised a staff that had
grown to 126. He was made a corporate
officer and as a member of the senior
management team, he began to play a
key role in the formulation of Centocor's
business strategy. Working closely with
Centocor's CEO, CFO and legal department, he helped develop the company's
partnering strategies.
At Centocor, Smith was also charged
with identifying key barriers to the
company's long-term success. One of

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�came the first employee of the new corporation. After writing most of the business plan in his home office, Smith
moved back to Baltimore from Philadelphia. In September 1993, he hired a
secretary, a financial officer, and his
wife, Susan, who is now the company's
director of project management and,
together, the small group formed the
core of Guilford Pharmaceuticals.
Scios Nova had been working on a
drug-delivery system, known as the
GLIADEL ®wafer, for treatment ofbrain
cancer. Although clinical testing of the
product had been completed, the results had not yet been analyzed. Because
"I BELIEVE THAT MORE IS ACCOMPLISHED
WHEN PEOPLE WORK TOGETHER TOWARD A
COMMON PURPOSE ."

Craig Smith, MD, president and CEO of Guilford Pharmaceuticals,which develops drug-delivery and neurological products.
the problems he identified was that his
own role consisted of functions normally carried out by the CEO. Thus,
when the company downsized-from
almost 1,500 employees to about 500Smith found himself among those looking for other opportunities.
In retrospect, Smith says, the dead
end at Centocor turned out to be a very
good thing, as it cleared the way for his
fourth organization-building venture:
Guilford Pharmaceuticals.
During the last few weeks of his tenure
at Centocor, Smith was contacted by a
recruiter who was looking for someone to
start a new companywithSolomonSnyder,
MD , a world-renowned neuroscientist
whom Smith had known from his days at

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johns Hopkins. It was from Snyder that
Smith learned of an exceptional opportunity to start a company from scratch with
promising intellectual property and technology that was being spun off another
company. Originally a small neuroscience
company based in Baltimore, Nova had
been purchased by the California biotechnology firm Scios, and had its name
changed to Scios Nova. The parent companywanted to keep theScios Nova products and research efforts that were complementary to its own efforts, while selling
the neuroscience work in progress.
Snyder believed the purchase ofScios
ova's products and technology would
form a sound basis for a new company.
Smith agreed and, in July 1993, he be-

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Scios Nova did not want to focus on
neurological research or drug delivery,
the wafer was included in Guilford Pharmaceuticals' initial capitalization.
Smith's team spent their first year of
business involved in an intensive search
for funding. Much of the company's
originally planned financing had fallen
through, and instead of the $27.5 million that Smith had expected, Guilford
had only $2 million to establish the new
company. Adding to this problem was
the prevailing financial climate in which
investment bankers simply weren't interested in underwriting start-up biotech
companies. Consequently, the company
remained at four employees, as Snyder
and Smith scrambled to find funding.
Because Scios Nova owned 80 percent of
the company, venture capital firms were
not interested in investing: They wanted
to own 80 percent of the company.
late in 1993 , Smith and Snyder invested their own savings in the company (a combined total of $750,000).
This convinced Scios Nova to invest
another $1 million in Guilford's future.

�Then, in june 1994, the company went
public, raising $15 million in an initial
public stock offering. This much-needed
infusion allowed Guilford to begin to
expand its manufacturing capabilities
as it filed a new drug application for
GLIADEL with the FDA.
y 1995, the company was firmly
launched. A follow-on public stock
offering directed toward institutional
investors raised an additional $19.5
million. By the end of the year, the
company had increased to nearly 40
employees, whose primary focus was
commercializing GLIADEL. A third
growth spurt the following year came
about as the company evolved from a
one-product company (GUADEL) to a
company with multiple drug development capabilities. Today, Guilford employs nearly 200 people and is involved
in the development of a variety of drugdelivery and neurological products.

ministration of chemotherapy drugs .
Through a marketing agreement with
Rhone-Poulenc Rorer (RPR) , Guilford
began marketing GUADEL in February
1997. This event was a major breakthrough for Guilford. No longer considered a development-stage company,
Guilford became one of only a handful
of biotechnology businesses that have a
marketed product.

PREPARATION FOR SuccEss
ife as a CEO really isn't all that different from life as a physician, says Craig Smith, MD. The founder,
[ president and CEO of Guilford Pharmaceuticals recently was asked by a group of Robert Wood
Johnson clinical scholars how difficult a transition it was for him to leave academic medicine for the
business world.

lJ

Success in either world, Smith says, is very much a product of good judgment. "Physicians are constantly
taking disparate bits of information and synthesizing them into a plan of action, atherapeutic plan. At times,
this is simple; at other times, we make decisions in consultation with others whose judgment we trust. With
a CEO, it's the same."
In medical school, men and women ore trained to work hard and to put in long hours. The some is required
of oCEO. Physicians must continually renew their fund of knowledge. likewise, the technical aspects of being
o CEO require constant upgrading of skills and acquisition of new information.

Guilford's lead product, the GUADEL
wafer, gained final federal approval in
September 1996, becoming the first brain
cancer treatment to be cleared by the
FDA for marketing in more than 20
years. The wafer, which is made of a
biodegradable polymer, contains BCNU,
or carmustine, a cancer chemotherapy
drug used in the treatment of glioblastoma multiforme, a particularly virulent form of brain cancer.
Approved for patients undergoing
surgery for recurrent brain cancer,
GLIADEL wafers are packed into the
cavity created when a tumor is excised
from the brain. Once implanted, the
wafers degrade over several months ,
allowing for the extended delivery of
high concentrations of BCNU directly
to the tumor site. In addition to permitting site-specific and controlled delivery of the drug, the new product eliminates the toxic and debilitating side
effects that accompany systemic ad-

®

Under the agreement, RPR holds the
rights to market GLIADEL globally, except in Scandinavia; RPR also has the
exclusive right of first offer on other
polymer oncology products developed
by Guilford. In return, Guilford shares
in profits from GLIADEL sales and receives other payments from RPR as various regulatory hurdles are cleared in the
U.S. and abroad . Additionally, RPR is

"Renewing, retooling- these come very naturally to me," Smith says. "We didn't receive training in
balance sheets and public stock offerings in medical school, but with the way health-core delivery is changing,
that might not be such o bod ideo."
Academic medicine is really very entrepreneurial, according to Smith, who compares it to o franchise
operation. Faculty and researchers get into business by being accepted by a larger institution with a big nome.
Johns Hopkins didn't give himo budget to start o new division in the Deportment of Medicine: it gave him
use of its nome. With that nome, he raised funds and leased space in the institution. The institution took 15
percent off the top of his earnings, and he was required to follow the rules of the "franchise."
It's up to the choir, program director or principal investigator to keep the franchise running, Smith says.
If he or she does poorly, the franchise doses and the space is leased to someone else to develop another
research program. Smith was successful of this mode of operation when he was in academic medicine, and
he enjoyed the challenge of building his franchise. Today, as a CEO, one of his greatest challenges still is to
find the resources to expand the company.
Afundamental contrast between business-at leas! business al Guilford-and academic medicine is
the emphasis on teamwork versus individual achievement, Smith says. "In the academic setting, the focus
is on who's bringing in the mosl money and who's work is being published in which journals. This approach
promotes individual achievement that often discourages collaboration," he says. "In a company like
Guilford, working in teams for a larger purpose is o way of life."

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·········· · ·············· · ······························ · ························· · · · · · · [ ! ]

IN ANIMAL STUDIES, THE GUILFORD COMPOUNDS HAVE BEEN
SHOWN TO REGENERATE NERVE TERMINALS LOST IN
PARKINSON'S DISEASE AND TO REVERSE THE FUNCTIONAL
ABNORMALITIES ASSOCIATED WITH THIS LOSS.

financing clinical studies of GLIADEL
for metastatic brain cancer and pediatric brain cancer.
Although Smith acknowledges that
Guilford has some distance to go before its
stockholders can expect the company's
products to generate healthy profits, he is
excited about Guilford's future. Part of
Smith's enthusiasm is based on achievements in the company's neuroscience program, including the completion of Phase
II clinical trials of the company's diagnostic test for Parkinson's disease. The new
product promises to improve detection
and monitoring of the condition, which
currently afflicts more than 1.5 million
Americans.

P

arkinson's disease is caused by the loss
of dopamine neurons in the area of the
brain that controls muscle tone and
movement. It is one of the most common of the neurodegenerative conditions
affecting older adults, but it is difficult to
diagnose in its early stages and impossible
to monitor using current methods.
Guilford scientists, however, have developed an imaging technique to measure
the density of dopamine neurons in the
brain. The new product, DOPASCAN Injection, has recently completed a
multicenter Phase lib study with the
Parkinson's Study Group.
Additionally, Guilford's research and
development team is concentrating on
developing drugs that may someday reverse the effects of Parkinson's disease,
as well as those of stroke, spinal cord
injury and other serious neurological
conditions. Researchers' efforts are centered around the new compounds, called
neuroimmunophilin ligands, through

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which nerve regrowth can be induced.
Building on findings by researchers at
johns Hopkins, scientists at Guilford demonstrated in laboratory experiments that
low concentrations of certain immunosuppressive drugs can be used to stimulate nerve regrowth. After discovering that
the neurotrophic activity of these compounds can be isolated from their immunosuppressive properties, the Guilford
team developed a series of compounds
with neurotrophic capabilities, but without the immunosuppressive effects.
In animal studies, the Guilford compounds have been shown to regenerate
nerve terminals lost in Parkinson's disease and to reverse the functional abnormalities associated with this loss. Smith
is unaware of any similar studies with
such dramatic results. "If anyone had
told me 10 years ago that it was possible
to make damaged nerves regrow and
regenerate, I would have said, 'So what?
They won't know what connections to
make,"' he says. "But that's what appears
to be happening. If the damaged nerves
can be stimulated to regrow, they seem to
'know' how to make the right connections on their own."
In March 1997, Guilford was granted
a U.S. patent covering the neurotrophic
applications of neuroimmunophilin
ligands, and the company hopes to begin clinical studies of the compounds
within the year.
Researchers at Guilford are also involved in neuroprotective research,
which focuses on preventing nerve cell
damage resulting from stroke and head
trauma, and in addiction research, which
focuses on developing nerve inhibitors
to block the pleasure effects of drugs

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such as cocaine, alcohol and nicotine.
Smith's ambition for Guilford is to
build it into a multibillion dollar concern-an aspiration that is not at all
antithetical to his desire to make the
world a better place. "Our company
does well by doing good," he says.
"Our mission is to become a world
leader in the discovery and development of drugs to improve human health
care and enhance quality of life. We're
also in business to build value for our
shareholders. While it's true that our
industry is competitive, we don't have
to conduct business in a way that is at
odds with our goal of improving the
lives of individuals confronted with
life-threatening diseases. " +

TINNITUS

CONTINUED

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3

plastic transformation of its circuitry.
"So we think tinnitus is the auditory
system's analog to the phantom-limb
sensation experienced by some amputees or people with peripheral nerve
damage," explains Lockwood. "This is
of much interest to us because we think
it provides a target for future research.
Understanding the mechanisms that
cause plasticity may provide a method
for preventing or treating tinnitus in
the future."
For Michael Deakin, who was a participant in the study, these results and
their potential for clinical applications
provide him with much hope for a future
life in which he can once again enjoy the
quiet that normally accompanies times of
relaxation, rest or concentrated absorption in a task. "To me," he says, "this
study is very, very significant."
Seed money for th e research described in this
article was provided by the UB Offi ce of Research,
with additional f unding from the UB Center for
Hearing and Deafness, the American Tinnitus
Association, the j ames H. Cummings Foundation
of Buffalo and th e National Institute on Deafn ess
and Oth er Communication Disorders, of the
National Institu tes of Health .

�the health sciences at UB.
As director of managed care with the
Emory University System of Health
Care, Bernardino oversaw sales, marketing, contracting, medical management and community relations for a
health-care system with net revenues
BY
A RTHUR
P AGE
of more than $1 billion. One of the
projects he oversaw was the consolidation of multiple system laboratories
1 ( l-f .\ ~ 1 F
D
t n r '
\If D has been named vice president
into a single laboratory system . Prior to
for health affairs at the University at Buffalo, effective Aprill, becoming director of managed care, he
was associate clinic director in this same
as announced by President William R. Greiner. Prior to coming area with the Emory Clinic.
Bernardino has been affiliated with
to UB, Bernardino served as director of managed care with the
the Emory University School of MediEmory University System of Health Care, in Atlanta, and was a cine since 1982. He has served as direcprofessor of radiology in the Emory University School of Medicine. tor of magnetic resonance imaging and
director of abdominal radiology at
At UB , he has assumed responsibility health sciences," he adds. "Western New Emory University Hospital and as a
as the chief officer overseeing the clini- York is very fortunate to have someone of professor in the Winship Cancer Cencal and collaborative activities of the his caliber become a part of our commu- ter. Before joining Emory, he was affiliuniversity's five health sciences nity. His joining us bespeaks the strength ated with the University of Texas Sysschools-medicine and biomedical sci- and potential not only of health sciences
tem Cancer Center and
ences, dental medicine, health related at UB, but also the excelM. D. Anderson Hospiprofessions, nursing and pharmacy. He lence of the region's healthtal and Tumor Institute
is also overseeing the university's rela- care community. "
in Houston , and with
Provost Thomas E.
tions with its affiliated teaching hospiEverett General HospiHeadrick, who
tal in Everett, WA.
HE WILL BE A FIRM LEADER WITH A CLE"AR
headed
the
A graduate of Case
search commitSENSE. OF ~·~E~T'~ ' .-~D TH
HE, ' ~u
Western Reserve Unitee that recomSCIENCES. - PROVOS T THOMAS E . HEADRICK
versity in Cleveland ,
mended BerBernardino earned his
tals and Roswell Park Cancer Institute. nardino , says he "blends an
medical degree in 1973
In addition , he is serving as leader for understanding and commitfrom Ohio State Univerthe health-science deans in planning ment to academic medicine
sity and completed his
and executingjoint and cooperative pro- with health-care business experience. residency in diagnostic radiology at
grams of teaching and research and is a He will be a firm leader with a clear George Washington University Hospikey member of the president's cabinet. sense of direction for the health sci- tal in Washington, D.C. In 1996, he
John R. Wright, MD , is continuing as ences. His leadership and decision- received an MBA degree from Roberto
interim dean of the UB medical school, making styles emphasize listening and C. Goizueta Business School at Emory
a position he assumed in january 1997 learning from his faculty members and University.
following the resignation of john P. the health and medical community, and
Certified by the American Board
Naughton, MD.
bringing people together for shared goals of Radiology, he is a past president
Greiner describes Bernardino's ap- and common benefits."
of the Society of Computer Body
pointment as "a historic win for UB. "
Headrick notes that among Tomography and has been active in
"His leadership experience and his Bernardino's charges will be develop- medical organizations, including the
vision for the place of medical education ing a five-year academic and financial Society of Magnetic Resonance
in the rapidly changing health-care field plan for the medical school and, more in Medicine and the Society of
will help bring focus and strength to the generally, guiding the planning for Gastrointestinal Radiologists. +

New Vice President Named
for Health Affairs

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Nancy Nielsen, MD,PhD,Named
Associate Dean for Student Affairs
ancy H. Nielsen, MD , PhD, has
been named assistant dean for Student Affairs at University at Buffalo School of Medicine and Biomedical Sciences. In this capacity,
she will be responsible for overseeing the academic and student affairs of
third- and fourth-year medical students.
ielsen, who earned her medical
degree from UB in 1976, is a clinical
associate professor of medicine at UB,
with teaching responsibilities at the Buffalo General Hospital.
She is also in private
practice in internal
medicine. Since 1995,
ielsen has served as
Speaker of the House
of Delegates for the
Medical Society of the
ew York (MSS Y) and has
served on MSSNY's state and federal
legislation committees and on the Task
Force on Health Care System Reform.
A frequent lecturer and radio and

INFINITI

television host on topics relating to
health, nutrition, infectious diseases and
women's health concerns, ielsen is
currently a ew York State delegate to
the American Medical Association
(AMA) , member of the AMA's Council
on Scientific Affairs and a member of the
board of directors of the ational Patient Safety Foundation, an AMA initiative formed this year. She is also past
president of the Eric County Medical
Society and the first woman elected president of The Buffalo General Hospital
staff, a position she held from 19961997. In 1996, ielsen was named
recipient of the Samuel P. Capen Award,
the UB Alumni Association's most
prestigious award. +

James P. Nolan Receives Alfred
Stengel Memorial Award
ames P. olan, MD, Distinguished
Service Professor and former chair
of the Department of Medicine at
the University at Buffalo School of
Medicine and Biomedical Sciences
for 16 years , has been named

recipient of the Alfred Stengel Memorial Award for outstanding service to
the American College of Physicians.
Selection is "based upon unusual
loyalty and exceptional contributions
to the aims and purposes of the
college, as well as the recipient's
outstanding influence in maintaining
and advancing the best standards of
medical education, medical practice
and clinical research, " according to
information provided by the college.
olan, an internationally recognized expert in
endotoxins and
liver function, disease and injury, is
also well known for his leadership in
the areas of affirmative action and
minority recruitment in medical education. As a Master of the American
College of Physicians, he has served
the college as governor, regent and
chair of the board of regents.
olan received the Stengel Award
on April20, during the college's 79th
annual session in San Diego. +

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New, Uniquely Collaborative MPH
Degree Program Established
BY

JESSICA

ANCKER

OR YI:.ARS PAIRICK

A

orRs

had been thinking about earning

a master's degree in public health (MPH), but he never found
an opportunity. After he earned his DDS from the University
at Buffalo School of Dental Medicine in 1986, he operated a
busy private practice and then joined the staff of the Buffalo

graduates will be better qualified to respond in a more informed way to changes
in health care and to take a more proactive role in helping to define workable
solutions to health-care problems. A second advantage, he says, is that "by understanding the determinants of health and
disease in our society, practitioners will
be better able to help prevent disease and
to contribute to the public debate influencing our health policy, making them
not only better health-care professionals,
but better citizens, too."
REFLECTING A NEW REALITY IN THE
ECONOMICS OF MEDICAL EDUCATION

While the course content for the collaborative MPH program addresses the
new economic realities facing medical
practices, the administrative structure
of the program reflects the new economic realities facing medical educa-

General Hospital.
His training prepared him well for
treating individual patients, but, Anders
says, he found himself encountering
situations where more knowledge about
public health, health policy and healthcare administration would have been
helpful. Rapidly changing health-care
reimbursement structures and the
Buffalo hospital mergers made him want
to learn more about administrative and
fiscal issues. In addition, Anders developed a subspecialty in treating
developmentally disabled patients, a
population whose dental needs are not
unique but whose cases may pose
special management problems.
Nevertheless, there was no MPH program in Buffalo where Anders could
study the issues that interested him.
The closest equivalent was the master of
science degree in epidemiology offered
by the University at Buffalo School of
Medicine and Biomedical Sciences, but
Anders felt that the degree was too research oriented for his needs.
This year that has changed. Anders
has a chance to study for his MPH and he
doesn't even have to leave the area. A
groundbreaking agreement between the
University at Buffalo, the State University of New York at Albany and Roswell
Park Cancer Institute, will allow physi-

cians and dentists in Buffalo to earn advanced degrees in public health from the
University at Albany's School of Public
Health. The collaboration is sponsored
by the Department of Social
"OUR MPH DEGREE IS INTENDED TO GIVE PRACTICAL
and Preventive
RELEVANCY TO PUBLIC HEALTH-A PROGRAM WHERE
Medicine at UB's
THE
STUDENTS CAN GO OUT AND WALK AROUND AND
School of MediSEE HOW EVERYTHING WORKS IN REAL LIFE."
cine and Biomedical Sciences
and Roswell Park Cancer Institute.
tion. After several years of tight state
"With the changes in health-care de- budgets, SUNY medical schools generlivery today-including a growing em- ally find it hard to win money for expanphasis on prevention-knowledge ofpub- sion. Instead, they can enter into interlic health issues has become increasingly campus cooperative arrangements to
desirable for physicians and other health- share existing resources.
care practitioners," says Maurizio Trevisan,
"This joint program will benefit both
MD, chair of UB's Department of Social of our institutions," says David C. Carand Preventive Medicine.
penter, MD, former dean of the Univer"A better understanding of the social, sity at Albany's School of Public Health.
public health and policy side of medicine "UB gains access to our nationally acwill greatly benefit physicians and other credited MPH and DrPH programs with
health practitioners," he says. "The a minimal investment, while the Uniknowledge acquired in the MPH pro- versity at Albany is able to help set the
gram will not only prepare health practi- standard of public health education and
tioners for a career in public health and expand its student base."
administration, but it will also equip a
'This is a concrete example of collabobroader range of these professionals with ration between SUNY units," Trevisan
tools that will enable them to better prac- adds. "It's an example of how things will
tice medicine." According to Trevisan, be in the future, with teleconferencing
one advantage of the program is that and cross-offerings. This collaboration

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represents a significant opportunity in a
time of shrinking resources. "

W

ithout a collaboration with Albany,
it's unlikely that UB could have created a new degree-granting program
without hiring more faculty, according to Arthur Michalek, PhD, associate
director for the Department of Educational Affairs at Roswell Park Cancer Institute and dean of the
institute's graduate division,
SUNYatBuffalo. "In
the present economic climate, we
have to be fairly innovative. If we want
new programs, we
have to fashion them
so they aren't going to
require a great number of new faculty, "
he says.
The schools
are implementing several innovative teaching
techniques to make a
success of this joint
venture between two
campuses that are
separated by some
300 miles. UB already offers
many relevant courses through the
Department of Social and Preventive
Medicine and as part of the master of
science program in epidemiology.
Through teleconferencing, additional instruction will be offered at a special facility at UB. In addition, Roswell Park is
expected to have a teleconferencing facility of its own in the near future.
Externship opportunities will be
provided for students in settings that
are expected to range from the Erie
County Department of Health to the
administrative offices of a health maintenance organization (HMO). Most
students will be able to earn credit for

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relevant courses they took while earning their primary degrees.
UB is implementing the program
gradually to ensure a smooth and cohesive transition, and only a few students
will be admitted initially, each of whom
must already have earned their MD or
DDS. Eventually, the MPH program may
also be opened to individuals from other
health professions. As the program
expands, Trevisan hopes to
create a dual-degree
program that would
allow medical students to earn an
MD and an MPH
simultaneously in a
four- or five-year
program.
THE "BASIC
SCIE CE"
ARM

OF

PREVE TIVE

MEDICINE

The MPH degree
integrates well with
UB'semphasis on primary
care, and it is expected to help UBattract students with a
public health perspective. The course requirements for the MPH will
be similar to those already in place
for the MS in epidemiology; however,
MPH students will focus more on public
health issues and will not complete a
research thesis, but instead will complete
internships in the community.
"Someone from the 'ivory tower'
might get tongue-tied when faced with
real public health situations in the
field, " Michalek says. "Our MPH degree is intended to give practical relevancy to public health-a program
where the students can go out and
walk around and see how everything
works in real life. "
Flexibility has been built in to the

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MPH program to accommodate as many
learning needs as possible, so students
can focus on specific areas of interest.
Citing an example about the importance
of this flexibility, Trevisan explains that
one of the requirements for completing
the three-year residency program in preventive medicine at UB is that students
earn an academic degree in either public
health or epidemiology. "This is training
that is seen as imperative for anyone
pursuing a career in preventive medicine. In a sense, public health and epidemiology represent the basic science arm
of preventive medicine. Therefore, it's
important that we allow students to tailor the MPH program to their specific
career goals and interests."
Trevisan is already receiving anumber of inquiries about the program.
Potential students are interested, he
says, because they recognize that public health training will help expand
their perspective from individuals to
populations, and from treatment to prevention. They also recognize that training in the fiscal and administrative aspects of medicine can enhance their
professional careers and their attractiveness to managed care organizations ,
hospitals and universities.
Anders applied for the MPH program
as soon as he heard about it, and became
the program's first student. He has already begun a course in cancer epidemiology. While in school, he will continue
to work nearly full time, so he expects it
will take several years to complete his
master's degree.
"I really think this makes a lot of
sense with what I've been doing professionally, " Anders says. Of course,
he adds, there are a few disadvantages
to being the first: "I have no one to
study with!" +
For more information on the MPH program, contact
Dr. j ohn Vena, acting director of graduate studies,
Department of Social and Preventive Medi cin e,
Univ ersity at Buffalo, 270 Farber Hall , Buffalo, NY,
14214. Phon e: (716) 829-29 75.

�~ ·

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ceptional for her maturity and composure. "I was with her when she received
a call of congratulations from the Secretary of State and she was very poised.
MONICA SPAULDING , MD , A LEAD MED I CAL OFF ICER AT
There's
something about her; she just
NAGANO' S SKATING EVENTS
has that little extra spark," she notes.
Spaulding spends most days as chief
HF
T -\;;'-\ LIPI Sl\.1 glided off the ice after her gold medal- of oncology at the U.S. Department of
winning figure-skating performance at the 1998 Winter Olym- Veterans Affairs Medical Center in Buffalo , but her avocation takes her to compics in Nagano, japan, she had a mandatory appointment petitions all over the East. In recent
months , she supervised drug testing at
with Monica Spaulding, MD, professor of medicine at the the World Cup Free Style Skiing team
University at Buffalo School of Medicine and Biomedical Sciences. competition in Sugar Loaf, Maine, and
the Olympic short-track skating trials in
Spaulding, one of four U.S. physi- Olympics in Atlanta, an offer she couldn't Lake Placid. Her venues also have incians in Nagano participating in drug refuse. There she met Carl Lewis,jackie cluded the 1997 Boston Marathon, the
testing, was lead medical ofJoyner and Michael] ohnson, 1997 U.S. Track and Field Championficer for the women's figure
chatted with 15-year-old ships in Indianapolis and the World
B y
skating, short-track skating
swimming phenomenon Cup water polo competition and the
L 0 I S
and long-track skating and
Brook Bennett, and got to 0 lympic track and field trials , both held
8
A K E R
some skiing events.
know the entire women's in Atlanta prior to the Olympics.
This was Spaulding's secswim team.
Those Summer Games-her first
ond Olympic experience. She
At Nagano, Spaulding Olympic experience-were unquestionwas lead medical officer in Atlanta in worked closely with the American and ably the pinnacle. Spaulding recounts 161996 for two hugely popular competi- Canadian women figure skaters and hour days, subsisting on turkey sandtions: track and field and the aquatic speed skaters. Her impressions of many wiches and the occasional Big Mac, and
events, including swimming, diving, of the athletes are memorable, both on loving it. "After the first week, we were all
water polo and synchronized swimming. and off the "stage." Spaulding says she exhausted," she says. "I don't think I've
The job is a gift from the gods for the very much enjoyed working with worked that hard since I was an intern."
avid sports fan and mother of two daugh- Lipinski. "She is a really neat kid. l had
agano wasn't much easier, as most of her
ters who are competitive athletes. "It's seen her around the games quite a bit events took place in the evening, with the
one of the greatest experiences I've ever and she was very easygoing, always mix- athletes often not arriving for testing until
ing with people and joking. She
had in my life," she says.
after midnight. "I usually got back to
Nagano is far removed from the lo- seemed to be having a very good
my room at two or three in the
cal competition in 1990, where time. And in the drug testing
morning, sometimes as late as
Spaulding's adventure began. She vol- area, she was a delight to work
four," she says.
unteered to do the drug testing for her with and just so excited to
Spaulding's job as lead
daughter's swim meet and found the have won the medal," she says.
medical ofexperience fascinating. Spaulding reSpaulding adds that she has
ficer was to
ceived her training and certification in worked with other young
make sure
time to handle testing for swimming Olympic athletes,
all test
and track and field for the 1993 World but feels that
samples
University Games in Buffalo.
Lipinski is exwere
Because she was certified to conduct
drug testing by the U.S. Olympic Committee (USOC) and the National Colle- At the dose of the
Olympic;,
giate Athletic Association, Spaulding was Spaulding and
contacted by the USOC and asked if she Lipinski again
would be interested in working at the crossed paths.

Keeping the Olympics on Track

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notified of their secollected and
lection and must
packaged withsign a form certifyout tampering,
ing the time of notiand that each
fication. They then
athlete certified
have an hour to apin writing that
pear for testing. If
the process was
they don't, a posiconducted
tive result is autoproperly. The
matically registered,
ingenuity of usSpaulding says.
ers, combined
Most competiwith the develtors appear as reopmentof everquested, however ,
more-advanced
and
their main task
performanceis to produce a urine
enhancing
drugs ,
has Spaulding enjoyed the unique cultural events at the Olympics such as this drum performance at the moguls venue in Hakuba. sample while being
observed, a predicatransformed
what should be a simple matter of letes' safety," she emphasizes, explain- ment that can give even a champion
collecting a urine sample into a closely ing that there have been several deaths pause. "Some athletes are around for
in cycling in recent years. "The problem hours because they are either dehydrated
monitored, painstaking procedure.
"No matter what you do with innova- with having a high red blood cell mass is or over-hydrated," Spaulding says. It's
tive drug testing, they are one step ahead your viscosity goes up and you can have under these circumstances that she
meets the big names who come accomof you," Spaulding says. She tells of a major stroke," she says.
Urine is analyzed for evidence of ste- panied by their managers, as well as the
athletes using catheters to fill the bladder with "clean " urine, strapping a con- roids, human growth factor and diuret- unheralded , and often more endearing,
tainer of urine to the body or hiding a ics, which can mask the presence of champions of lesser-known contests.
Once samples are procured, athletes
urine bag in the vaginal cavity. Athletes some performance-enhancing drugs , as
select
a testing kit, certify its pristine
selected for testing now are observed well as flush evidence of illegal drugs
condition,
divide the sample between
constantly from start to finish to pre- from the system, Spaulding says. Tests
two
bottles,
label and seal the bottles,
also look for stimulants, narcotics and
vent such transgressions.
The new drug of choice, particularly beta blockers , sometimes taken by place them in the packing kit , seal the kit
for distance events, is erythropoietin, marksmen to slow the heartbeat and and testify in writing that all procedures
used to stimulate red blood cell produc- gain an extra moment of dead calm in were followed properly. One sample is
tested, the other is frozen. If sample A is
tion and boost the amount of oxygen which to take aim and shoot.
positive,
sample B also is tested. If both
available to muscles , Spaulding says.
Drug testing is conducted on all medal
results
are
positive, appropriate sancNot long ago, this effect was accom- winners and world-record setters, as
tions
are
imposed.
Labs were set up in
plished more crudely by transfusing red well as randomly selected athletes. Comagano
to
conduct
the testing, which
cells, a·process referred to as blood dop- petitors who set a record for their counhad
to
be
completed
within 24 hours.
ing. "In Nagano, the drug testers weren't try also may ask to be tested to validate
Nagano was a very unique experireally confident in their ability to test for their performance.
ence for Spaulding when compared to
the hormone, so instead they checked
hile drug testing was instituted to her other sporting venues, in large part
the hematocrit prior to the event and if
protect
athletes from dangerous due to the unbuffered exposure she had
it was past a certain level, the plan was
substances
as much as to maintain to japanese culture. "I was housed in a
to not let the athlete compete because it
a
level
playing
field , the process small room, furnished with a tatami
was a health risk, " Spaulding explains.
This test was only done in the biathlon itself is designed to insure a reliable mat, futon and low table. A communal
and cross-country events, and to the result that will withstand legal chal- sink and bathroom were down the hall ,"
best of Spaulding's knowledge, no one lenges. Athletes selected for testing are
O LY MP ICS CONTINUED ON PAGE 22
was excluded. "This test is for the ath- escorted off the field of competition,

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Magnificent
BUILDING LOTS

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OLYMPICS CONT ' D FROM PAGE 21

she explains, adding that women and
men's quarters were completely segregated. "I was surrounded by Japanese
women from all walks of life, and it
really was a wonderful experience. They
helped me improve my Japanese a lot. "
Other cultural highlights included a
two-day trip to Kyoto with her fellow
medical officers and the many hours she
spent exploring Nagano on foot. During
one such walk, she came upon police
officers roping off the street and waited
patiently with a gathering crowd to see
the emperor and his wife stroll past her.
"He was a kindly looking man and his
wife was probably one of the loveliest
older women I've ever seen," she says.
When she wasn't working her events
or spending time deciphering the sched-

ule for her daily bus rides to the venues,
Spaulding made good use of her "Infiniti"
pass, which gave her access (not necessarily a seat) to any Olympic event she
wished to attend. This enabled her to
take in a whirlwind of drama , from
Jonny Moseley's gold-medal performance on the moguls, to the U.S.-Canadian men's hockey game, the subsequent Czechoslovakian-Canadian match
(with tickets selling for more than $300),
and the women's Chinese-Finn hockey
match in which the Finns won a bronze
medal.
Now back into her normal routine
of work, Spaulding has had time to
reflect on her two-week experience
in Nagano and admits to looking
forward to an opportunity to participate in future Olympics. "It was an
adventure," she says. +

TAKE TW

•••

AND CALL ME IN THE
MORNING!
f;'\d ~o~r

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As a former president of
the University at Buffalo
medical school Alumni
Association and a
practici ng surgeon in
Western New York
for many years, I've come to understand what
members of our profession desire in a home
site - privacy, tranquility, fresh air, and pristine
surroundings.
The Summit at Scherff is a truly extraordinary
residential development, unrivaled in Western
New York. Nestled in the hills of Orchard
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Specifically as an escape from the fast-paced
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Laboratory and Fellowship Named
in Honor of Louis Bakay, MD
he Louis Bakay Neurosciences
Laboratory for Surgical Anatomy
and Neuropathology at Buffalo
General Hospital was opened in
December 1997. The lab is named
in honor of Dr. Bakay, head of the
hospital's Department of Neurosurgery
from 1961 until his retirement in 1985
and emeritus professor of neurosurgery
at UB. In addition, the Louis Bakay Fellowship has been established in the
hospital's Department of Neurosurgery.
"Dr. Bakay has done pioneering laboratory research on the specialized nature
of the blood-brain barrier and on radioactive nuclear scanning of the brain. He
has contributed significantly to various
areas of research pertaining to metabolism of the brain," says Walter Grand,
MD , clinical head of the Department of
Neurosurgery at Buffalo General Hospital (BGH) and clinical professor of neurosurgery at UB, who worked closely
with Bakay for more than 10 years.
According to Grand, Bakay was the first
to introduce electron microscopy to

Western New York, having brought the and gentle person and exemplary scholar
first such microscope with him when he who is not in the least bit bitter toward
came to Buffalo General Hospital in 1961 . his fellowman. These are wonderful qualiIn addition to his medical research ties that came out of his terrible ordeal.
accomplishments, Bakay is also known It's for all these reasons, both his pioneeras a medical-history scholar and as an ing research, as well as the stature of the
author of several books, one of which is man himself, that we felt it fitting to
his autobiography, titled Gallery ofGhosts. dedicate the laboratory and fellowship to
"In this book he recounts the trials and him at Buffalo General. "
Th e Louis Bakay
tribulations he encounLaboratory , which is
tered in his homeland of
codirected by Grand and
Hungary during WWII
Peter Ostrow, MD , of the
and his escape to Sweden through Nazi- and
Department of NeuropaRussian-occupied territhology at BGH, is detory, " says Grand , who
voted to training neuroadds that Bakay speaks
surgical residents in new
five languages and is a
surgical techniques usmaster editor in English
ing laboratory anatomiDr. Wolter Grand and Dr. louis Bakay
and a notably accomcalspecimens. Residents ,
plished translator of medical archival fellows and attending physicians corredocuments from Latin to English.
late surgical anatomy with surgical pro"This is a man who has led a very cedures, and also design and refine new
special life," says Grand. "He came to this procedures. The lab is also available for
country late in life and had to repeat his use by other surgical subspecialties and
entire training at Harvard before he could for training pathology residents.
A private dedication for the laboraresume his work. Yet what I find most
remarkable about him is that despite all tory was held on December 9, 1997,
the horror and deprivation he experi- with Bakay, who is now 80, in attenenced in his life, he grew to be such a kind dance with his wife , Nancy. +

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Acceptance is granted to qua lified students without regard to race, color, rel!gam or national origin.

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Shedding Light on
Treatment of Lung Cancer
FDA APPROVES NEW PHOTOSENSITIVE DRUG

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U S Food and Drug Administra-

tion approved the use ofPhotofrin®, a light-activated drug used
in photodynamic therapy (PDT), for treatment of patients with
early-stage lung cancer. PDT is a multistep process in which a
harmless drug absorbed by body tissues is activated by light and
releases cytotoxic substances inside tumors. This new modality of
cancer treatment has been pioneered over the past three decades by
Thomas J. Dougherty, PhD, chief of the Department of Radiation
Biology/Photodynamic Therapy at Roswell Park Cancer Institute
and professor of radiation oncology at the University at Buffalo
School of Medicine and Biomedical Sciences.
The use ofPhotofrin in PDT
Photofrin is injected intraBY
is an option for people diagvenously into the patient, a
KEVIN
nosed with early-stage lung
procedure that is sometimes
cancer who are not eligible
done in an outpatient setCRAIG
for surgery and radiotherapy.
ting. Within approximately
LOIS
"In clinical trials, approxitwo days, the drug concenBAKER &amp;
mately three-quarters of the
trates in cancer cells, and
S .A .
patients had a complete rephysicians can then deliver a
sponse following treatment
of light to the tumor
beam
UNGER
and about half of them are
using a fiberoptic and an
cancer free in long-term
argon-driven laser. When the
follow-up," says Stephen Lam, MD, head Photofrin absorbs energy from the light,
of the bronchoscopy program at British it produces a molecule called singlet
Columbia Cancer Agency ofVancouver, oxygen, an active form of oxygen
Canada, and a clinical trial investigator derived from endogenous oxygen. Durfor the new drug. QLT Photo Therapeu- ing its one-millionth-of-a-second life
tics, a Canadian biotechnology span, this highly reactive molecule oxicompany, has exclusive license to the dizes anything it touches, killing the
Photofrin patent, which is held by cancer cells but sparing surrounding
Roswell Park Cancer Institute.
tissue. In some cases, necrotic tissue
"This is the very first approval for this and exudate are removed through a bronnew therapy in North America for which choscope two days after the initial
the intention is to cure the patient. Some procedure. Principal side effects of the
patients in the trial are still free of drug include skin sensitivity to light for
disease 10 years after PDT treatment," four to six weeks; some patients also
says Dougherty.
experience inflammation at the treatln photodynamic cancer therapy, ment site, causing varying degrees of

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shortness of breath and coughing.
Lung cancer remains the number-one
cause of death by cancer in the United
States for both men and women.
Currently, the five-year survival rate for

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· · · · · · · · · · · · · · · · · · · · · · · · · · · · · · · · · · · · · · · ·· · · · · · · · · · · · · · · · · · · · · · · · · · · · · · · · · · · · · · · · · · · · · · · · · · a

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found out, as early as the 1930s and
again in the 1960s, but was discontinued due the unavailability of technically
advanced equipment. The big leap in
technology came in the 1980s, when
lasers that could focus light at precisely
correct wavelengths through endoscopes
were developed. Since that time, scientists around the world have used PDT
successfully on esophageal, bladder,
stomach, oral and cervical cancers, and
Photofrin-PDT is currently approved
for use in Canada, japan and several Euro"TO ME , THE GREATEST VALUE OF PHOTOFRIN IS THAT
pean countries. Prior
IT HAS THE 'MAGIC BULLET' PROPERTIES THAT HAVE
to january of this year,
BEEN TALKED ABOUT IN ONCOLOGIC RESEARCH FOR SO
Photofrin and the
LONG," LIEBOW SAYS . REFERRING TO PDT'S ABILITY TO
PDT laser equipment
had only been apIMAGE AND TREAT AFFECTED CELLS WITHOUT DAMAGE
proved
by the FDA for
TO SURROUNDING TISSUE.
treating late-stage
esophageal cancer.
Because light doesn't penetrate far
Building on the success of Dougherty's
into tissue, PDT can only be used on work, Buffalo General Hospital opened a
tumors that are on or near the surface of Photodynamic Therapy Center in March
organs, accessible by an endoscope or 1995 , under the direction of
exposed surgically. Also, because it is a ThomasS. Mang, PhD, former director of
local therapy, it is not appropriate to Roswell Park's PDT center and research
blood-borne cancers. Although not associate professor of oral and maxillofatherapeutic for all cancers, PDT is less cial surgery at UB. In addition to patient
expensive, quicker and safer than many treatment, the Buffalo General center is
conventional cancer therapies. Under conducting Phase II and III trials on two
Dougherty, Roswell Park's Photody- other photosensitive drugs, tin ethyl
namic Therapy Center is continuing to etiopurpurin and Foscan, the latter of
develop new and improved PDT drugs, which is being studied for its efficacy in
participating in clinical trials of new treating recurrent oral cancers.
In the fall of 1997, Mang and his
drugs and therapies and investigating
the mechanisms that make PDT work. colleagues Ronald Allison, MD, and
Dougherty began his innovative work Vitune Vongtama, MD, of the UB Departwith PDT in the early 1970s, following ment of Radiation Oncology, and B. Dale
a serendipitous discovery in his lab in- Wilson, MD, of Roswell Park and UB
dicating that a chemical being used to Department of Dermatology, announced
identify live cells in culture could kill preliminary results from an FDA trial
the cells if they were exposed to light. In they were conducting on PDT for use in
the years that followed, he and his col- treating Kaposi's sarcoma, as well as
leagues
began experimenting with pho- external chest-wall lesions from recurthe 178,000 Americans diagnosed with
tosensitive
chemicals in combination rent breast cancer. Presenting at the
lung cancer every year is 14 percent,
with
conventional
lamps to kill tumors European Cancer Conference in Hamaccording to the American Cancer Society. "This new drug approval is particu- that had spread to the skin. Work of this burg, Germany, they announced that 75
larly significant since it is now possible type had been attempted, they later percent of the Kaposi's sarcoma lesions
to detect early-stage lung cancer much
more successfully than has been the case
in the past," says Dougherty. Roswell
Park is now planning to combine early
detection and appropriate treatment with
PDT as a new option for lung cancer
patients. This work, according to
Dougherty, will be available through
Roswell's Division of Surgery under
john Urschel, MD, and Timothy Anderson, MD, and through the Division of
Medicine under Gregory Loewen, DO.

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~

HURWITZ &amp; FINE, P.C.
I

[ATTORNEYS AT LAW

were reversed completely and another
19 percent showed partial reversal. Also,
92 percent of the chest-wall lesions
associated with breast cancer were completely reversed and the remaining 8
percent showed partial reversal. The
only adverse reactions experienced by
subjects were due to sun exposure while
the photoreactive agent used was still
active, a period of several weeks.
Mang, who has done extensive research
with PDT and is a longtime colleague of
Dougherty's, says these results support
earlier findings indicating that photodynamic therapy holds great promise
for treating cancerous lesions of the
skin and that, in general, it appears to be
most effective when used to treat small
tumors that are discovered early. "Compared to other treatments for Kaposi's
sarcomas, PDT is easier on the patient,
you can treat large numbers oflesions at
one time and the cosmetic results are
very good," he says. "Also, PDT doesn't
interfere with HIV status and any other
treatment patients may be receiving. "
Results with recurrent breast cancer
of the chest wall were equally exciting,
Mang says. "PDT is a very localized
treatment that does not interfere with
chemotherapy, and there are none of
the usual side effects of cancer therapy.
Many lesions can be treated in one session, and the therapy is repeatable if the
response isn't complete."
In yet another research endeavor related to Dougherty's original work, scientists in the Great Lakes Biomedical
Laser Institute-a comprehensive,
multifacility "laser center without
walls," headquartered at US-scientists
and clinicians are further exploring the
use of the laser as a tool in the diagnosis
and treatment of cancers, both alone
and in conjunction with drug sensitizers, such as Photofrin.
The center is directed by Charles
Liebow, DMD, PhD, professor of oral
and maxillofacial surgery in the UB
School of Dental Medicine, who is na-

tionally recognized for his research and
treatment of precancerous and malignant lesions of the oral cavity, as well as
at other sites, including the pancreas.
Liebow, who works closely with Mang,
notes that it is only within the past 30
years that lasers have gained acceptance
in the medical and dental professions as
a means of safely removing lesions from
the body. Over the past few years, researchers at several member centers of
the laser institute have used the combined laser-Photofrin therapy under special license both experimentally and
clinically for other animal and human
malignancies. "To me, the greatest value
of Photofrin is that it has the 'magic
bullet' properties that have been talked
about in oncologic research for so long,"
Liebow says, referring to PDT's ability
to image and treat affected cells without
damage to surrounding tissue.
Liebow further points out that
Photofrin combined with PDT is also
proving to be a highly precise method for
staging cancer. "Photofrin is absorbed by
premalignant cells in a way that is directly proportionate to the transformation of the cell from a premalignancy to
a malignancy. By taking a fluorescent
reading of the cell and measuring the
intensity of the fluorescence, we can
measure in a very exact way how far the
cell has evolved toward cancer, so this
has the potential to become a very powerful staging tool," explains Liebow, who,
along with Mang, has published studies
on this area of research. "Anytime you
have a site where there is a transformation of cells going on and you don't know
which specific area is further progressed
than another, you can find the spot with
Photofrin and use it to guide a biopsy.
When working with premalignant cells,
you then have the ability to provide
treatment that is preventive by selectively destroying lesions before they
become cancerous. This, to me, is the
greatest hope for this new drug and
PDT in oncology research." +

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SERVICING
THE LEGAL
NEEDS OF THE
HEALTH SciENCEs
CoMMUNITY
• Managed Care
• Purchase &amp; Sale of Practices
• Business &amp; Tax Planning
• HCFA Safe Harbor Regulations

Physician

and Physician Self-Referrals
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&amp; Public Entities

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Counseling
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• Representation Before
Government Agencies on
Audit &amp; Business Issues
• Faci lity Finance
and Construction
• Credentialing
and By-Laws
• Hospital/Medical Staff Issues

Please contact
Robert P. Fine or
Lawrence M. Ross
at 716-849-8900

1300 Liberty Building
Buffalo, New York

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THE
CARITAS
MEDICAL ARTS
BUILDING
A Unique Partnership with
St. Joseph Hospital

Harlem Road, Cheektowaga
(connected via enclosed walkway to St. joseph Hospital)

500 - 8,000 Sq. Ft. Medical Office

Suites Now Available
For More Information
Ciminelli Development Company, Inc.
Centerpointe Corporate Park
350 Essjay Road
Williamsville, NY 14221

716/631-8000

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Image of Neural Activity Provides
Objective Measure of Attention

it takes longer than without the distractions. When the brain is forced
to divide its attention, however, as
in processing two cocktail-party conypical scenario: You're at a party, versations at once, it flounders.
listening to your friend's vaca"The brain can only divide up its
tion plans, while straining to over- resources so much," says David
hear the gossipy conversation Shucard, PhD, a coinvestigator on the
nearby. Your brain, meanwhile, research. Ralph Benedict, PhD, assisis mustering its neuronal re- tant professor of neurology; Alan
sources to allow you to concentrate on Lockwood , MD, professor of neurolboth conversations at once.
ogy; and Danielle McCabe, psycholeuroscientists at the University ogy graduate student, complete the
at Buffalo have been able to produce research team. Results of their work
an image of this
were presented at
neural activity in
the Society for
one of the few
euroscience
studies using
meeting in New
positron emisOrleans in Octosion tomography
ber 1997.
(PET) and elecKnowledge
trophysiology
about the neurosimultaneously
physiology of atto study brain
tention will infunction. Their
crease
underfindings may
standing and improvide new inprove treatment of
sight into the basuch attention
sis of many_ attendisorders as attention disorders.
tion deficits and hyper"WE'RE LEARNING
"We're learning how
vigilance, a symptom of
the brain attends to imposttraumatic stress
HOW THE BRAIN
portant information
disorder in which perand screens out what
sons are unable to
ATTENDS TO
is not important," says
screen out irrelevant
JanetShucard, PhD, UB
stimuli, Janet Shucard
IMPORTANT INFORMAassistant professor of
says. It also provides
neurology and a lead
information about the
T ION AND SCREENS
researcher on the
neural demands of any
study. "Using electrojob that commands
OUT WHAT IS NOT
physiology and PET,
intense concentration.
we can identify how reThe team collected its
IMPORTANT."
sources are allocated.
electrophysiology data
What we end up with
via electrodes attached
is an objective measure
to the scalp while study
of attention. "
subjects wearing earphones identiTheir findings showed that the fied a specific syllable-in this case,
brain can successfully complete a the syllable "ba"-from a sequence
task requiring focused attention even of syllables . Neural actions generin the presence of distractions, but ated in response to this task, or

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event-related potentials, appear on
a computer-generated map that
reflects the pattern of electrical
responses from the brain. The amplitude of a specific point on this wave,
called the P300, indicates the acuteness of the brain's response to the
relevant stimuli.
The P300 was recorded under three
conditions:
Sustained attention-detecting
the target syllable without any
auditory interference
Focused attention-detecting the
target while ignoring distracting
stories played simultaneously
Divided attention-detecting the
target and also paying attention to the
content of the stories
"We found a huge reduction in the
P300 in response to the dividedattention task," says David Shucard.
"These findings are relevant to any
activity that demands constant
attention, such as piloting an aircraft
or monitoring sensitive instruments.
This is one of the major causes of
'human error'-people get off target. "
Simultaneous PET scanning
pinpointed areas in the brain
responsible for auditory attention tasks
by recording the areas of increased
cerebral blood flow during the tests.
"By combining PET and electrophysiology , we are able to determine
the location of major brain areas
that are responsible for these different
types of attention processes, as
well as the time it takes the brain
to process information when there
are different demands on attention,"
Janet Shucard says.
The researchers are applying their
findings to persons with attention
deficit disorder and posttraumatic
stress disorder, as well as persons with
sleep disorders, some of whom have
trouble concentrating on tasks. +

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of chemicals obtained from ginkgo
leaves-to treat age-related deterioration in brain function. Several human
trials there have shown positive reinkgo biloba, prescribed widely in sults, but little research has been done
Europe to improve brain function, to replicate these findings in animals,
appears to improve learning and according to Winter.
memory in rats and prolong their
Winter's earlier research with rats
life, a study at the University at showed that a set of tasks performed in
Buffalo has shown. The unexpected an apparatus called the radial maze
could reliably detect
positive effect on longevdeficiencies in learning
ity has surfaced in re" THAT FINDING
and memory related to
search to determine
age. In the current
ginkgo biloba's effect on
LEADS US TO
study,
Winter used 20age-related cognitive
SPECULATE THAT
deficits, using rats as an
month-old rats, which
IN ADDITION TO
animal model.
were assigned a diet
"At a certain point in
GINKGO BILOBA'S
that included either
our analysis, we realized
ginkgo
biloba extract
PURPORTED
that the rats who were
or no extract. Over sevBENEFICIAL EFFECTS
receiving ginkgo biloba
eral weeks, the animals
ON BRAIN FUNCTION ,
were living substantially
performed tasks in the
longer than those who
radial
maze that reTHE EXTRACT
were not receiving the
quired them to master
MAY ALSO HAVE A
extract," says Jerrold C.
new challenges andrePOSITIVE EFFECT ON
Winter, PhD, professor of
tain learned informapharmacology and toxition over time.
LONGEVITY,"
Results
cology in UB's School
showed that rats
of Medicine and Bioreceiving ginkgo
medical Sciences and
biloba extract
author of the study.
learned
more
"That finding
quickly and made
leads us to specufewer errors than
late that in addition
control animals
to ginkgo biloba's
and-unexpectpurported beneficial
edly-that they
effects on brain
lived an average
function, which our
of
five months
study supports, the
longer.
Winter
extract may also
found
a
significant
have a positive effect
positive relationship beon longevity. " Results of
tween
the
amount
of active ingredient
the study appear in the January 1998
and
the
degree
of
learning.
The standard
issue of Physiology and Behavior.
dose
during
most
of
the
study
was 50
Ginkgo biloba is available in the U.S.
mglkg.
However,
one
subgroup
of anias a dietary supplement but is not apmals was assigned to receive EGb 761 in
proved by the FDA as a medical treatdoses of 100 mg/kg followed by 200 mgl
ment. It is prescribed widely by physikg, interspersed with periods when they
cians in Germany and France in the
performed tasks while receiving no exform of EGb 761-a complex mixture

Ginkgo Biloba Study Indicates
Po~tive Effect on Longevity

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tract. Results showed that at the highest
dose, errors declined by 50 percent.
"Despite the urgent need to discover
drugs able to prevent, delay , ameliorate or cure age-related memory impairment and the degenerative
dementias, progress has been slow,"
Winter states in the article. Two major
reasons for this, he notes, are a lack of
agreement on appropriate animal models and on their applicability to humans when memory and cognition are
concerned, and the absence of a drug
proven to work in humans that could
serve as a standard in animal tests.
"The present demonstration of positive effects of EGb 761 in animals, a
substance for which abundant evidence
exists of at least a modestly beneficial
clinical effect in humans, is encouraging on both points," Winter says. "The
challenge now is to identify, from this
mix of perhaps 200 chemicals, which
chemical or chemicals are producing
these pharmacologic effects. "
This study was supported in part by
Dr. Willmar Schwabe Gmbh &amp; Co. of
Karlsruhe, Germany, manufacturer of
EGb 761.
B A K E R
L 0 I 5

Saliva Shown to Be as Reliable as
Blood forDNA Screening
a!iva appears to be as good as blood
as a source of genetic material
needed to screen people for inherited diseases, a University at Buffalo oral biologist has shown.
The discovery could simplify the
screening process enormously, eliminating the risks and complications of
handling, storing and transporting
blood, including the risk of contact
with blood-borne viruses. It also would
allow persons who cannot or will not
give blood to be screened, and would
be a boon to the needle-phobic.

�[1] . . . . . . . . . . . ... . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .. . .
"This is such a clean, reliable, quick, was conducting a major research
easy test," says Rob van Schie, PhD, a project involving genetic screening of
children for potential
UB postdoctoral associrisk factors for juvenile
ate in the Department of
"SOME PATIENTS
periodontal disease, a
Oral Biology and lead reMAY BE RELUCTANT
particularly aggressive
searcher on the discovTO SUBMIT TO
form of gum disease that
ery. "There are no
PHLEBOTOMY
tends to run in families.
needles. Samples can be
PROCEDURES ON
Mark Wilson, PhD , forcollected by untrained
RELIGIOUS OR
merly of the UB School
personnel. And it's great
CULTURAL
GROUNDS,
of Dentistry , is the
for children, because
WHILE OTHERS MAY
project leader on that
they love to spit."
SIMPLY BE APPREHEN·
research .
Forensic scientists
Excited by the possiSIVE; HENCE, AN
have used many materibility of having his
als as a source for DNA
ALTERNATIVE TO THE
young research subjects
evidence, but blood is
USE OF BLOOD FOR
spit into a test tube incurrently the most comGENETIC STUDIES MAY
stead of being stuck with
monly used source of
BE DESIRABLE."
a needle , van Schie
DNA for genetic testing, both for clinitested the salivary
:t..
DNA theory using
cal use and for basaliva and blood
sic research, van
from himself and
Schie notes. Unforhis wife. Finding
tunately, the use of
the genetic material
blood has many
in
the blood and sapractical disadvanliva samples indistages and inherent
tinguishable , he
limitations.
collected blood
"Blood sampling
is invasive and -..~_...,,
and saliva samples
from 69 adult volpainful, and it inunteers
to test the
volves a potential
theory further.
risk of contamination
Using polymerase chain reaction, he
with hepatitis and the human immunodeficiency virus," he states in his study, was able to show that DNA from saliva
published in the October 1997 issue of was as precise as that from blood in
revealing polymorphisms in two genes
the journal of Immunological Methods.
"Some patients may be reluctant to thought to play a role in the developsubmit to phlebotomy procedures on ment of juvenile periodontal disease.
The results pertain to only two genes
religious or cultural grounds, while
others may simply be apprehensive; whose sequence is known, van Schie
hence , an alternative to the us e cautions, and although its potential
of blood for genetic studies may be appears very promising, the method
desirable."
has not been proved universally. Like
Van Schie was struck with the idea others, he predicts that genetic screenfor the study after hearing a news ing for disease-the subject of a recent
report on the Unabomber investiga- editorial in the journal of the American
tion telling of successful DNA analy- Medica/Association-will become rousis of dried saliva from a stamp used tine in the near future .
by the suspect. At the same time, he
Van Schie's findings could increase

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this momentum, and make genetic
testing easily available to populations
presently outside the medical
mainstream.
The research was supported by the
ationallnstitute of Dental Research. +
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AKER

Nitric Oxide for Treatment of
Aspiration Pneumonia May Do
More Harm than Good
ohn Belushi, Janis Joplin , Jimi
Hendrix and several other pop icons
are believed to have died due to
regurgitation of stomach contents
into the lungs while they were unconscious, an event that precipitates aspiration pneumonia.
Aspiration pneumonia also is one
of the leading causes of death in pregnant women, who are at risk of developing the condition when they give
birth under general anesthesia or
undergo other surgery.
Researchers in the University at
Buffalo's Department of Anesthesiology have found that inhaled nitric
oxide, a new therapy being tested to
treat serious respiratory ailments, may
do more harm than good if used for
aspiration pneumonia. They have
reported new information about the
progression of this potentially fatal form
of lung inflammation.
Results of their studies were presented
recently at the American Society of
Anesthesiologists annual meeting in
San Diego in November 1997.
"We're looking at the mechanisms
involved in aspiration-induced lung injury, how we can treat this disease, and
how to avoid things that make the
injury worse," says Paul Knight, MD,
professor and chair of the UB Department of Anesthesiology and senior
researcher on the studies.

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Aspiration of stomach contents oc- synergistically to produce an increase in
curs during unconsciousness brought reactive nitrogen species that are toxic
on by anesthesia, trauma, drug over- to lung tissue. There was no effect of the
dose or other circumstances. When un- combined therapies on lung injury from
conscious, a person loses the natural aspiration of gastric particles. Knight
reflexes that prevent food particles and! says these two etiologic agents have
or stomach juices from entering the been shown to use different pathways in
respiratory system. Stomach contents producing inflammatory lung injury.
"This observaoften are highly acidic.
tion, along with our
When acidic matter
previous findings
comes in contact with
of
microvascular
tissue lining the air
and
functional
passages of the lungs,
changes
with exa cascade of events reposure to nitric
sults that can lead to a
oxide and oxygen,
decreased ability of the llii!IIIIP:!~~"l
suggests that caulungs to transport oxytion should be
gen. Even when the
taken in using
process is internitric oxide in
rupted , the initial
acute inflammatory
damage inflicted may
lung injuries that
eventually prove fatal
also require oxygen
due to later-occurring reac"WE'RE LOOKING AT
therapy," he says.
tions, Knight says.
THE MECHANISMS
Another study by the
One of the newest therasame team centered on
pies for treating inflammaINVOLVED IN
the relationship of the
tory lung injury is inhaled
ASPIRATION-INDUCED
concentration
of food
nitric oxide, which can bring
LUNG INJURY. HOW
particles aspirated to the
dramatic improvement in
severity of lung damage
WE CAN TREAT THIS
oxygenation in some paand the progression of
tients. Giving supplemental
DISEASE. AND HOW
the damage. Results
oxygen also is a standard
TO AVOID THINGS
showed that most of the
therapy to improve oxidadamage occurred durTHAT MAKE THE
tion during lung injury.
ing the first five hours
Knight and colleagues exINJURY WORSE. "
after
aspiration and
amined administration of
remained
unchanged
oxygen and nitric oxide toafter
15
days.
"
ot
surprisingly,"
Knight
gether in acid-injured and normal lungs,
using rats as an animal model. They says, "the higher the concentration of
administered nitric oxide at the rate of particles, the greater the damage."
Researchers on the studies, in
80 parts per million for five hours to
addition
to Knight, were
ader
lung-injured animals, while the animals
ader-Djalal,
MD,
Bruce
A.
Davidson,
also received either 90 percent oxygen
or 20 percent oxygen. Lung injury was and J erzy C ios, MD , of th e UB
caused either by acidic liquid or gastric Department of Anesthesiology; David
particles. A control group with normal Steinhorn, MD, of the UB Department
of Pediatrics; and Kent Johnson , MD,
lungs also was examined.
Results showed that when lung injury of the University of Michigan Departwas caused by aspiration of acidic liq- ment of Pathology. +
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uid, nitric oxide and oxygen worked

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researchers were able to devise a way to
"tease out" what the children expected to
happen due to the Ritalin versus how the
drug actually affected them. Published
last year in Experimental and Clinical
Psychopharmacology (1997. Vol. 5, o.
l. 3-13), the study took more than five
years to complete and involved four consecutive cohorts of 40 children each,
with follow-up studies conducted in regular school classes and laboratory settings.
"Across all those cohorts, all those settings, all those kids, we found no evidence that expectancy does anything. It
makes no difference whether a child with
ADHD thinks he took a regular pill or a
placebo," reports Pelham. "So all those
people arguing over the years, saying
that these kids would learn to attribute
their successes to taking a pill, turned out
to have unfounded concerns."
The drug study Pelham is currently
conducting on the long-acting version of
Ritalin is being done within the context
of the Saturday Treatment Program. He
is planning other, ongoing studies to
take place within the settings of both it
and the Summer Treatment Program.
Despite the many successes of his programs and studies, Pelham is the first to
admit that much work still needs to be
done to better understand this complex
disorder. "Right now there is no single
effective, comprehensive treatment program for ADHD; it hasn't been discovered." But the high societal cost of juvenile delinquency, adult incarceration,
alcohol and drug abuse and mental health
services reminds him and his colleagues
every day how critical it is to continue to
search for effective treatments for children with ADHD before their lives spin
out of control in ways that even the most
organized and focused of individuals
would have difficulty overcoming.
For more infonnalion on the summe1 treatment program 01 the upcoming clinical oial of long-acting
methylphenidate, call (716) 645-3650, ext. 373.

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AWord from the Dtrector of Development
B Y

L I N D A

J .

C 0

R D E R ,

P H 0,

C F R E

to the many people
who supported the School of Medicine and Biomedical Sciences a tan exemplary level in 1997.Inso doing,
they became members of the Class of 1997 of the
school's esteemed james Platt White Society.
Since its founding in 1986, the society has grown from
a small group of dedicated alumni to an organization of more
than 200 alumni and friends, who are generous investors in the
future of medical education and training at UB. An executive
committee of active society members works with the development staff to increase philanthropy to the school and plan
recognition events for members. Publishing this list of the
school's most generous donors gives Dr. Wright and the executive committee, as well as all of us who work daily on behalf of
the school, an opportunity to show our appreciation.
The society currently offers two types of recognition:
annual and lifetime. A gift within any year confers an
annual membership for the following year. Honorary
lifetime society membership is granted when cumulative
contributions of a couple or an individual reach $50,000.
There are also a few "special" members who received
"term memberships"for a specified time frame. Although
no new special memberships have been granted since
1992, we honor those earlier commitments. Most special
memberships will expire at the end of 1999.
Historically, the society held a recognition event
in the fall, retroactively compiling a list
of those whose gifts had been received from
November 1 of the previous year through October
31 of that year. Last year, the society (by a mail
vote) decided to migrate to a calendar year. Thus,
this year's Honor Roll includes donors of contributions received from November 1, 1996, through
December 31 , 1997.
For a variety of reasons, the james Platt White
Society Class of 1997 is the largest and most
prestigious in the history of the organization.
These individuals and couples who support the
medical school at an outstanding level are seen as
its closest friends. They receive additional information throughout the year and invitations to
certain medical school and university events. Best
of all, this group keeps expanding. It is a welcom-

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ing and inclusive organization, since the more "best friends"
the school has, the more excellent it becomes.
Many donors made year-end gifts in both 1996 and 1997;
our overall total gift amount is higher than it would have been
in twelve months. Others made only one gift during the 14
months. Some made gifts in honor of a class reunion; thus, the
current list includes gifts from two sets of reunion classes.
There are several individuals and couples who are in the
society for the first time, based on two or more gifts made at
different times during the 14-month year. Finally, those marked
with an asterisk (*) are GOLD members of the societyGraduates of the Last Decade-whose gifts during this time
frame totaled between $500 and $999. The lower entry level for
more recent graduates was instituted during 1996 to encourage newer alumni to take their place in this society.
Most gifts were designated for the school's General Fund,
disbursed at the dean's discretion. A few gifts were designated
for special projects, such as the Neuroanatomy Museum, or
as contributions to departmental funds, which are disbursed
at the discretion of the chair for such uses as research seed
money or student medical association activities. Donors
designated most of the larger gifts for a particular purpose,
generally for named endowments.
Living donors listed in this Honor Roll collectively contributed $997,429 to theschool.In addition, the school
received more than $130,000 from testamentary
trusts and bequests during this time frame. We are
deeply grateful for all gifts to the medical school,
especially those that have the potential to make a
transforming difference in the quality of medical
education and residency training offered at UB.
Read through the roster of members. Thank
your friends and colleagues listed here for their
outstanding support. If you are not yet in this
group, please consider increasing your contributions to the school. The executive committee would
like to see this group continue to grow, and increase its significant impact on the academic environment of the UB School of Medicine and Biomedical Sciences. +
Linda]. Corder (Ly n) is associate dean and director of development. She
may be reac hed by phone at (7 16) 829·2773 or by E- mail at
ljcorder@acsu.buffa lo.edu

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The
James Platt White
Society

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Lifetime Members

When cumulative contributions
reach $50,000 or an irrevocable
deferred gift is completed for
$100,000 or more, a couple or
individual is granted lifetime
membership in the society.
ames of Founders are
repeated in an annual category
when they make a new gift.

Mrs. Catherine Fix

Dr. Eugene]. Hanavan] r.

Martinsburg, WV

Buffalo, NY

Dr. JohnS. &amp;: Mrs. Doris M.
Parker-Latrobe, PA

Dr. Thomas F. Frawley

Chesterfield, MO

Richard]. agel, M.D.,&amp;: Mrs.
Florence Nagel

Dr. &amp;: Mrs. Edward Shanbrom
Santa Ana, CA

Mrs. Christina Gretschel Genner

Orchard Park, NY

Ms. Pamela F. Skaper

Potomac, MD

Dr. Elizabeth P. Olmsted Ross

Hamburg, NY

Dr. &amp;: Mrs. Pasquale A. Greco

Buffalo, NY

Dr. and Mrs. James]. White] r.

Buffalo, NY

Buffalo, NY

Dr. Glen E. &amp;: Mrs. Phyllis K.
Gresham-Snyder, NY

Dr. Syeda F. Zafar &amp;: Ms.
Mona S. Zafar

Dr. Thomas]. &amp; Mrs. Barbara L
Guttuso-East Amherst, NY

UB's founders envisioned a
school to train students for
service to the community.
The society's Founders help
to actualize that vision by
providing support for programs that enrich the academic environment and
enhance medical training.
Dr. Kenneth M. &amp;: Mrs.
joan Alford-Buffalo, NY
Mrs. June M. Alker

Williamsville, NY

Buffalo, NY
Mrs. Morris Lamer

New York, NY
Mrs. GraceS. Mabie
Orlando, FL

Dr. Charles D. Bauer &amp;: Mrs.
Mary A. Bauer

Dr. Eugene R. &amp;: Mrs. june A.

Williamsville, NY
Dr. Joseph &amp;: Mrs. Helene
Chazan-Providence, RI

Richard]. agel, M.D.,&amp;: Mrs.
Florence Nagel

Dr. Philip D. &amp;: Mrs. Colleen
Morey-Williamsville, NY

Orchard Park, NY

I Professors '

Hilton Head Island, SC
Buffalo, NY
Miss Thelma Sanes

Williamsville, NY

Dr. Kenneth M. &amp;: Mrs. Joan

Philip B. Wels, M.D.,&amp;: Mrs.
Elayne Wets-Buffalo, NY

ALford-Buffalo, NY
Buffalo, NY
Dr. joel M. Bernstein

MEMBERS

Dr. joseph G. Cardamone

Eden, NY

I Dean ' s Circle

Dr. Thomas F. Frawley
Chesterfield, MO

Individuals or couples qualify
as members in the Dean's
Circle with generous gifts of
$25,000 or more.
Dr. Richard Ament

Dr. George MEllis Jr.&amp;: Mrs.
Kelly Ellis-Connersville, IN

Williamsville, NY

Mrs. Grant (Evelyn) Fisher

Lakeview, NY

Ms. Rose M. Ellerbrock

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East Amherst, NY
Dr. Richard B. &amp;: Mrs. Ellen B.
Narins-East Aurora, NY
Dr. Bernice W.

oble

Amherst, NY
Dr. james&amp;: Mrs. Marcella
Phillips-Buffalo, NY
Dr. Seth A. Resnicoff

Concord, NH

Mr. Eugene M. &amp;: Mrs. Susan W .
Setel- Buffalo, NY

Lewiston, NY

I

Mr. W. Russell Hurd

Sun City, AZ

Buffalo, NY

r

Albany, NY

Mr. Arthur H . Judelsohn

Dr. John C. Newman

p

Buffalo, NY
Dr. Myron Gordon

Tonawanda, ,'JY

Dr. Warren R. Montgomery Jr.

Amherst, NY

Dr. Robert]. Gillespie

Dr. Albert G. Rowe

Dr. Earl S. Gilbert

Buffalo, NY

Dr. Willard &amp;: Mrs. Clarice
Bemhoft-Snyder, NY

f

Circle

A strong faculty is central to a
great university as are the
supporters whose annual gifts
range from $5,000 to $9,999.

Dr. Elizabeth P. Olmsted Ross

Buffalo, NY

f

Dallas, TX

Dr. Jack C. &amp;: Mrs. Patricia
Fisher-Lajolla, CA

Williamsville, NY

Dr. Kenneth H. Eckhert Sr. &amp;:
Mrs. Marjorie Eckhert

Dr. Kenneth Z. Altshuler

Dr. Albert C. &amp;: Mrs.
Linda Rekate

ANNUAL

Dr. joseph &amp;: Mrs. Helene
Chazan-Providence, RI

Fellows within the school
bring added depth to postgraduate study. Within the
society, Fellows are honored
for gifts that total $2,500
to $4,999.

Dr. Harold &amp;: Mrs. Anne Brody
Amherst, NY

Mr. Sheldon Berlow

Dr. Willard &amp;: Mrs. Clarice
Bemhoft-Snyder, NY

Fellows' Circle

Dr. Richard B. &amp;: Mrs.
Ellen Narins-East Aurora, NY

Williamsville, NY

u

Circle

Just as a department chair
leads a program , donors of
leadership gifts in the range of
$10,000 to $24,999 are given
special recognition.

Dr. Eugene]. Hanavanjr.

Dr. Charles D. Bauer&amp;: Mrs.
Mary A. Bauer

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East Amherst, NY

I Chairs '

Mindell-Buffalo, NY
Founders' Circle

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Drs. Robert &amp;: Claudia
Smolinski-Orchard Park, NY

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Scholars ' Circle
Scholars within the society
made gifts to the school
totaling $1,000 to $2,499
during the past year. Young
Scholars (*) are graduates of
the last decade who qualified
with gifts of $500 to $999.

Drs. Evan &amp; Virginia Calkins

Dr. Penny A. Gardner
Los Altos, CA

Hamburg. NY
Drs. Andrew &amp; Helen M.
Cappuccino*-Lockport, NY
Dr.

icholas C. Carosella

Dr. Arthur C. &amp; Mrs. Klein
Los Angeles, CA

Dr. Ronald F. Garvey

Dr. Robert A. Klocke

Dallas, TX

Williamsville, NY

Dr. Kenneth L. Gayles

Dr. &amp; Mrs. Franklyn G. Knox
Rochester, MN

Appleton, NY

Buffalo, NY

Dr. Yung C. Chan

Dr. Lawrence H. &amp; Mrs. ancy
Golden-Eggertsville, NY

Dr. Jacob S. Kriteman

Draper, VA

Dr. William S. Andaloro

Dr. &amp; Mrs. Norman Chassin

Dr. Peter H. Greenman

Dr. Paul S. Kruger

Caledonia, NY

Williamsville, NY

Fairfax Station, VA

Watertown, NY

Dr. Salvatore Aquilina

Dr. Michael E. &amp; Mrs. Joan
Cohen-Williamsville, NY

Dr. Glen E. &amp; Mrs. Phyllis K.
Gresham-Snyder, NY

Dr. Thomas]. Kufel

Lockport, NY
Dr. George &amp; Mrs. Susan
Bancroft-Hamburg, NY

Dr. Mark &amp; Mrs. Kathleen
Comaratta-East Amherst, NY

Dr. Robert T. Guelcher

Dr. Ivan W . Kuhl

Erie, PA

Wimberley, TX

Drs. Kevin &amp; Elizabeth P.
Barlog-Amherst, NY

Lyn Corder, Ph.D.

Gerard T. Guerinot, M.D., &amp;
Mrs. Geri Guerinot

Drs. Joseph L. &amp; Marie L. Kunz

Buffalo, NY

Dr. Charles A. Bauda

Dr. &amp; Mrs. Daniel E. Curtin

Rochester, NY

Boynton Beach, FL

Orchard Park, NY

Dr. Mala R. Gupta

Dr. Ralph T. &amp; Mrs. Rita
Behling- San Mateo, CA

Richard H. Daffner, M.D., &amp;
Mrs. Alva K. Daffner

Rochester, NY

Dr. Richard A. Berkson

Pittsburgh, PA

Williamsville, NY

Dr. Stanley B. Lewin

Rancho Palos Verdes, CA

Dr. Nedra]. Harrison

Carlisle, PA

Dr. Harold Bernhard

Dr. David R. &amp; Mrs. Sherrye
Dantzker-Ros1yn, NY

Buffalo, NY

Drs. Roger S. &amp; Roberta A.

Dr. Donald R. Hauler

Buffalo, NY

Dr. Theodore S. Bistany

Dayer- Buffalo, NY

Pensacola, FL

Dr. David L. Marchetti

Buffalo, NY

Dr. Robert]. Dean
Kinston, NC

Dr. Reid R. &amp; Mrs. Elenora M.
Heffner- Buffalo, NY

Dr. Willard H. Boardman
Winter Park, FL

Danvers, MA

Marilla, NY

Lockport, NY
Dr. Andre D. Lascari

Poestenkill, NY
Dr. Harold]. &amp; Mrs. Arlyne
Levy- Amherst, NY

Mrs. Gilda L. Hansen

Buffalo, NY

Dr. Jack &amp; Mrs. Inez Lippes

Buffa lo, NY
Dr. Michael A. &amp; Mrs. Glenda
Mazza-Spencerport, NY

Gerard]. Diesfeld, M.D.

Dr. Orvan W. Hess

Dr. Dennis L. Bordan
Port Washington, NY

Arcade, NY

North Haven, CT

Dr. Melvin B. Oyster

Dr. William]. Hewett

Harry L. Metcalf, M.D. , &amp;
Kaaren]. Metcalf, Ph.D.

Dr. Suzanne F . Bradley

Niagara Falls, NY

West Hartford, CT

Williamsville, NY

Whitmore Lake, Ml

Dr. Robert Einhorn

Dr. John M. Hodson

Dr. Merrill L. Miller

Dr. Martin Brecher

North Brunswick, Nj

Williamsville, NY

Hamilton, NY

Amherst, NY

Dr. &amp; Mrs. Russell Elwell

Dr. James B. Bronk
Napa, CA

Mayville, NY

Dr. Dennis C. &amp; Mrs. Suzette
HoUins*-Greer, SC

Dr. Maynard H. Mires Jr.
Georgetown, DE

Dr. Melvin M. Brothman

Snyder, NY

Dr. Domonic F. &amp; Mrs.
Margaret E. Falsetti
Lewiston, NY

Robert M. Jaeger, M.D.

Dean Mitchell , M.D.

Allentown, PA

Cortland, NY

Dr. Kenneth L. &amp; Mrs. Jane
Jewel- Mountain Lakes, NY

Satellite Beach, FL

Dr. Stephen T. &amp; Mrs. Mary

Dr. Joseph F. Monte

Dr. George H. Mix

New York, NY

Dr. John A. &amp; Mrs. Karen
Feldenzer- Roanoke, VA

Dr. August A. Bruno

Dr. Helen MarieS. Findlay

Joyce-Buffalo, NY

Buffalo, NY

Buffalo, NY

Eggertsville, NY

Dr. John D. Mountain

Dr. William M. Bukowski

Drs. Susan Fischbeck &amp; Patrick
T. Hurley- East Concord, NY

Drs. James R. KanskiJr., &amp;
Genevieve Kanski

Eggertsville, NY

Dr. Arthur W . Mruczek Sr.

Dr. Thomas D. &amp; Mrs. Grace A.
Flanagan- Williamsville, NY

Dr. Paul B. Karas*

Medina, NY

Rancho Mirage, CA

Buffalo, NY

Dr.

Dr. Jennifer L. Cadiz

Dr. Neal W . Fuhr

Getzville, NY

Mechanicsburg, PA

Williamsville, NY

Dr. &amp; Mrs. Kenneth Kim
Clinton, NY
Dr. Hans F. Kipping

Sylvania, OH

Ms. Deborah Elliott Brown

Buffalo, NY
Dr. William M. Burleigh

Manhasset, NY

irrnala A. Mudaliar

Dr. Richard L. Munk

Williamsville, NY

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Dr. Masao Nakandakari
Honolulu, HI

Dr. Edwin A. Salsitz
ew York, NY

Dr. Charles S. &amp;: Mrs. Anne R.
Tirone-Williamsville, NY

Dr. &amp;: Mrs. Marvin Z. Kurian
Williamsville, NY

Dr. Nancy H. Nielsen
Orchard Park, NY

Dr. Arthur]. &amp;: Mrs. Elizabeth
Schaefer- nyder, NY

Dr. Bradley Truax
Lewiston, NY

Dr. Timothy T. &amp;: Mrs. Cynthia
ostrant-Saline, Ml

Dr. james N. Schmitt
Kenmore, NY

Dr. joan A. Vivona&amp;: Mr.
Robert L. DeiszJr.*-Elma, NY

Harry L. Metcalf, M.D., &amp;:
Kaaren]. Metcalf, Ph. D.
Williamsville, NY

Dr. john&amp;: Mrs. Michelle M.
O'Brien*-Pinellas Park, FL

Dr. Robert . Schnitzler
San Antonio, TX

Dr. Coolidge S. &amp;: Mrs. Edith Y.
Wakai-Honolulu, HI

Dr. Thomas P. &amp;: Mrs. Sandy
O'Connor-East Amherst, NY

Dr. Adolphe].&amp;: Mrs. ancy L.
SchoepOin-Tucson, AZ

Dr. Arnold Wax
Henderson , NV

Mrs. Marguerite T. O'Gorman
Eden, NY

Dr. joseph I. Schultz
Harbor City, CA

Drs. Charlotte C. &amp;: Hyman
Weiss-Highland Park, Nj

Dr. Kathleen A. O'Leary &amp;:
Mr. Michael]. Collins*
Buffalo, NY

Roy E. Seibel, M.D. , &amp;: Mrs.
Ruth H. Seibel-Eggertsville, NY

Dr. Frederick D. Whiting
Vestal, NY

Dr. Molly R. Seidenberg
Rochester, NY

Dr. Gary J. Wilcox
Carlsbad, CA

Dr. Arthur M. eigel
Guilford, CT

Dr. Richard G. Williams
Clearfield, PA

Dr. john B. Sheffer
Williamsville, NY

Dr. John R. &amp;: Mrs. Deanna P.
Wright-Williamsville, NY

Dr. Timothy S. &amp;: Mrs. Karen S.
Sievenpiper-East Aurora, NY

Dr. Gregory E. Young
Holland, NY

Dr. Byron A. Genner Ill
Potomac, MD

Dr. james A. Smith
Orchard Park, NY

Dr. Wende W. &amp;: Mr. W illiam].
Young Ill-Canandaigua, NY

Dr. Charles D. Kimball
Bellevue, WA

Dr. Robert G. Smith
Savannah, GA

Dr. Franklin&amp;: Mrs. Piera
Zeplowitz-Buffalo, NY

Dr. Clara A. March
Buffalo, NY

Dr. Donald H. Sprecker
Leeds, MA

Dr. David C. &amp;: Mrs. Susan D.
Ziegler-Walnut Creek, CA

Dr. Mark W. Welch
Rochester, NY

Dr. Ralph M. &amp;: Mrs. june M.
Obler-Los Angeles, CA
Dr. joseph]. O liver Jr.
Rock Springs, WY
Drs. Dean E. &amp;: Donna W.
Orman-East Amherst, NY
Dr. Victor A. &amp;: Mrs. Virginia
Panaro-Snyder, Y
Dr. Margaret W. Paroski
Buffalo, NY
Dr. Robert]. &amp;: Mrs. Patricia M.
Patterson-Snyder, NY
Dr. Norman L. Paul
Lexington, MA
Dr. Clayton A. &amp;: Mrs. Susan
Peimer- Eggertsville, NY
Dr. Victor L. Pellicano
Niagara Falls, NY

john]. Squadrito, M.D.
Troy, Y

Special Members
A few individuals and couples
were granted multiyear
memberships based on
generous gifts made between
1989 and 1993. For most,
special recognition will be
granted through December
1999. All membersh ips in the
society are now made only on
an ann ual basis.

Dr. james M. &amp;: Mrs. Margo W .
Strosberg-Schenectady, NY

Dr. Bert W. Rappole
jamestown, NY
F. T. Riforgiato, M.D.,&amp;: Mrs.
Mary-Cecina W. Riforgiato
Buffalo, NY
Dr. Richard R. Romanowski
Williamsville, NY

Dr. Burton &amp;: Mrs. Gloria
Stulberg-Buffalo, NY
Dr. Michael A. Sullivan
Williamsville, NY

Dr. David W. Butsch
Montpelier, VT

Dr. MichaelS. Taxier
Worthington, OH

Dr. Charles H. Rosenberg
Stamford, CT

Ms. janet F. Butsch
Aurora, CO

Dr. Wayne C. Templer
Corning, NY

Dr. Thomas C. &amp;: Mrs. Georgia
L. Rosenthal-Orchard Park, NY

Mrs. Marvin (Helen) Winer
Sarasota, FL

In Memoriam
The fo llowing individuals left
generous bequests or made
arrangements for gifts from
testamentary trusts to be given
to the School of Medicine and
Biomedical Sciences during
the past year.

to ensure accuracy in these

Elizabeth A. Storch
Middleport, NY

Dr. john Y. Ranchoff
Fairview Park, OH

Dr. john Naughton
Buffalo, NY

every effort

Dr. james F. &amp;: Mrs. Lillian
Stagg-Tucson, AZ
Dr. William C. Sternfeld
Sylvania, OH

Dr. Harold Pescovitz
Cincinnati, OH

Dr. John L. Butsch
Buffalo, NY

Dr. &amp;: Mrs. James C. Tibbetts
Madison, WI

lists. Please contact Mrs.
Mary Glenn in the Medical
School Development Office
if we have made an error or
if you would like your
name(s) to be listed
differently in future
recognition documents.
Send mail to: UB
Medical School Development Office, 3435 Main
Street, Building #22,
Buffalo, NY 14214-3013.
Phone: (716) 829-2773.
Fax: (716) 829-3395.

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�[5;] . . . . . . .... . . . . . . . . . . . . . . . . . . . . .... ...... . . .... ... . . . .
The Beginning of My Ouest
BY

P

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AST SPRING I HAD THE OPPORTUNITY to hear Dr.

Carlos Roberto

jaen deliver a lecture on smoking cessation during our
third-year clerkship in family medicine. In that 60minute lecture, he opened my eyes to the serious side
effects that tobacco use can have on a patient's health and the
important role physicians can play in helping a
Pam ela Crowell is a fourth -year

patient to quit. His lecture was very
motivating, and after class I found myself asking him how I could learn more
about the topic. He had made me suddenly aware of how little I knew about
smoking cessation and how ill prepared
I felt as a future family physician.
This was the beginning of my quest
to become a smoking cessation specialist. I did not want to follow in the
footsteps of so many clinicians who
ignore the problem of tobacco use because of patient resistance and lack of
time. I wanted to learn how to discuss
tobacco use with my patients and how
to avoid alienating them in the process.
In subsequent discussions I had with
Dr. jaen, we decided that I would gain
the most valuable experience from
direct interaction with both the patients
and their physicians. As a result, we
chose an inner-city primary-care
facility, the Deaconess Family Medicine
Center, as my primary work site.
Our goals at the family medicine center
were twofold: (l) to increase the identification of smokers, and (2) to improve the
amount and quality of smoking cessation
counseling offered to patients at the center. We attacked our first goal by devising
a new charting system. We added smoking status to the vital signs and problem

list and designed a separate smoking cesstudent at the University at Buffalo School
sation progress note that was added to
of Mcdicint• and Biomedical Sciences.
each smoker's chart. My second role was
to provide more intensive smoking cessa- stand my ground instead of running in
tion counseling. This sometimes meant the opposite direction. I would inquire as
simply talking with the patient about rea- to how much they knew about the effects
sons why he or she should consider quit- of smoking on their body. "It's my body.
ting. Other times, it entailed assisting the I can do what I want with it," I was told.
patient in finding alternative activities to I would try a different angle. "Do you
lighting up a cigarette during times of have children?" I asked. I wasn't always
stress. Over the course of four weeks, I able to get the patient to admit to the
talked with several hundred patients. It importance of cutting back on his or her
did not take
long to realHE HAD MADE ME SUDDENLY AWARE OF HOW LITTLE I
ize that the
best way to
KNEW ABOUT SMOKING CESSATION AND HOW ILL
learn about
smoking cesPREPARED I FELT AS A FUTURE FAMILY PHYSICIAN.
sation was
through the
patient's own experiences and attitudes.
tobacco use, but I was often surprised at
I would often take the opportunity to the number of positive responses I retalk with patients as they sat in the exam ceived from simply initiating an open
room waiting patiently to be seen by their conversation. The patients themselves
physician. I introduced myself as a medi- began to approach me, saying, "I've been
cal student and mentioned that I was trying to cut back on my cigarettes for
trying to learn more about smoking. Each years. Do you know anything that may
patient reacted in a different way, and I be able to help me?"
tried to cater my approach to each one's
Whenever I encountered patients who
response. Some patients resisted vehe- had successfully quit smoking, I enthusimently. "I'm not interested in quitting," astically asked how they accomplished it.
they would tell me. I learned quickly to Some gave credit to their own willpower,

®

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others to a change in daily routine, or
hypnosis or prayer. I discovered that the
process was a very individual one but also
one with great rewards.
Another valuable learning experience
was my participation in a Stop Smoking
Clinic at the Roswell Park Cancer
Institute. There was a wide variety of
participants, ranging from young to
old, first-time quitters to relapsers, and
smokers to nonsmokers.
The class was taught by Dr. K.
Michael Cummings, a nationally recognized tobacco expert. He talked
about all aspects of smoking, from the
history of the tobacco industry, to the
ingredients of cigarettes, to the effects
of nicotine on the body, to various
behavioral modification techniques. At
the end of the sessions, I was thankful
to have taken the class and was once
again reminded that the best teachers

WNY's

of all were the participants themselves.
One gentleman had returned to smoking after quitting for five years. "The first
time I was able to do it cold turkey, right
after I was hospitalized for a heart attack.
I didn't touch them after that. I didn't even
crave them, but then life started to get the
best of me. Stress, you know? I was worrying about paying the bills all the time
and the next thing you know I was lighting up a cigarette again, not even thinking
about how much extra money each pack
was costing me," he explained. It was a
serious addiction, both physically and
psychologically.
Dr. Cummings listened to each story
intently, then offered his own best anecdotes. One participant said, "I've tried
everything: the patch, the gum, walking, drinking water. I just can't stand to
go without them. Giving up cigarettes is
like losing my best friend." Hearing

these words, I wondered, "What could
Dr. Cummings possibly say to that?" He
always came up with something else
that the person could try, a new way to
think about the problem or a new behavioral modification technique.
One day, at the end of the month , I
was talking with Dr. Cummings and
sharing with him how impressed I was
with his ability to help so many people
quit smoking. A smile crept across his
face as he peered over his desk and
replied, "Pam, I've never been able to
make even one patient quit smoking.
The patient doesn't quit smoking because of anything I tell her to try. The
patient quits smoking because she is
ready to quit herself."
I walked out of the room adequately
mystified, once again humbled by the
oft-forgotten role that the patient plays
in her own health. +

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a

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�l!!l.

................................... . ......... . .................... . .....

scrub in on the consummate

ousopportunitytoobserveand

psychiatrist, part general
medical doctor and part law-

have been retired 11 years and

surgeon's cases. One day , my

yer. I am enjoying my work

founder, president and CEO of

am enjoying it. I'm still active

good friend and classmate, Dr.

as well as enjoying traveling

HealthCare Plan , has been

and doing well with my tita-

Ferdinand Paolini, and I were

and playing tennis.

elected board chairman of the

nium right hip and post-myocardial infarction, both in 1996.
!live one-half mile from Marine

co-retractor holders on a thowas

non-profit and provider-based

on Lesterhill Lake and fish a lot,

very slow but meticulous sur-

recently certified in medical di-

health plans. The December 15,

take care of my home and small

gery, Dr. Stewart paused and

rection for long-term care by

1997, issue of Newsweek maga-

garden. My grandson is enter-

the American Medical Direc-

zine listed the highest rated

ing his MD residency this spring.

asked," eed to rest your arms
'Dr. Pawlini'7" Ferd replied ,"!
don 't know Dr. Stewart, they've

tors Association. Rosemarie
Santora Lamm, his wife, re-

HMOs in the U.S. and THMOG
member plans accounted for the

writes:

been completely numb for the

ceived her PhD in Applied

top five-scoring health plans, and

Thought you'd all like to see

last 30 minutes. " The surgical
team all relaxed a bit and even

Medical Anthropology in De-

11 of the top 18. HealthCare

cember 1997.

Plan, under Goshin's direction,

THEODORE W .

BOB

COLLINS ,

Koss ,

' 43 ,

' 41 , ]

three of the class of March

ARTHUR

EDW I N

R.

LA MM,

' 60,

Stewart "The Superb" chuckled a little. A great man could
show a little humanity at times.
has

MAX A. S C HNEIDER , ' 49 ,

been elected chair of the

a-

tiona! Council on Alcoholism
1943. On the left is

JOHN

M ARA N T Z ,

' 65 ,

of the Pathology Department
Center in Corona, CA.

Ambulatory and Community

effective january 1, 1998. He

Ml: In September 1996, I be-

has served on the NCADD

came corporate chairman of Di-

FLET C HER ,

has

been appointed vice-chair of

Gardens, Florida; in the middle
RICHARD

KE N NETH BROMBE R G , ' 75,

at Corona Regional Medical

and
Drug
Dependence
( CADD) for a two -year term,

iS

' 70 ,

was a founding member of
THMOG.

has
accepted a new position as chair

CA L VI N

of Palm Beach

Do N oHu E

GOS HIN,

The HMO Group (THMOG), a
national alliance of integrated,

racic sympathectomy case. After about 1 and l/2 hours of

R .

K E NN ET H

M A TASAR ,

Pediatrics at the SUNY Health
Sciences Center/Brooklyn
(downstate).

' 68 ,

writes from Bloomfield Hills,

Tequesta, Florida; and to his

board since 1983. Widely

agnostic of William Beaumont

right is me, (lOO Waterway Rd,

known in the field of alcohol-

Hospital, a 930-bed teaching

R O BERTS BU R N S, ' 8 3,

Apt. 201A, Tequesta, FL

ism and other drug addictions

hospital , as well as a 190-bed

ated from the University of Mem-

33469). I think it is great we

as a teacher, author, lecture

satellite hospital. We perform

phis in December 1997 with a

live together, play golf together

and film producer, Schneider

nearly 400,000 imaging stud-

master's degree in playwriting.

is the director of education for

ies annually and have 35 radi-

His play "Zen and the Fear of

the Positive Action Center at

ologists, 24 residents and 11

Flying" was produced in Pitts-

Chapman Medical Center in
Orange County, CA. He is a

fellows. Judi and I have two
sons. Our younger son is in his

burgh this year.

recipient of UB's Alumni Life

second year of medical school

and associate together all the
time and are well. We go out to
dinner all the time, which is
great. We would love to hear
from any of you and have you
come and see us. We will have

Achievement Award.

attorney in

1

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W ILLIAM

S ULLI V A N ,

'55,

writes: After 35 years of gen-

bad . The best to all.

eral psychiatry and psycho' 47 ,

analysis, I have changed my

writes: Another Dr . john
Stewart memory. In 1948, I was

professional work to forensic
psychiatry. I find this new

an intern at M.M.H. on the sur-

work interesting and demanding . One must be part

CHARLES

D .

ROSS,

gical service. l had the marvel-

B

f

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recently, I heard a familiar voice

ew York City. His

from the past. Looking up, I

wife is a third-year medical stu-

much medicine has changed.
We are glad we are retired. Too

a

l

o

SaW PAU L

dent at Columbia University
College of Physicians and Sur-

practice at St. joseph Mercy
Hospital in Ann Arbor. (I'm in

in orthopedic surgery.

PM&amp;R.) As it turns out, Paul
and his family live around
the corner! Two '85ers on the

has
been promoted to captain
in the U.S. Naval Reserve Medical Corps.

p

S HIELDS ,

y

s

c

B E R KOW I TZ, ' 85 ,

who has joined a nephrology

geons who is planning a career

J O HN

reports:

While making the rounds

at Harvard. Our older son is an

a good time together. Can't believe its been 55 years and how

JON WAR D N E R , '85,

gradu-

' 68 ,

a

n

same block-there goes the
neighborhood!

5

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�········ ······· · ················ ·········· ····················· ·················· ······ ·[! ]
THOMAs P. SMITH , JR. ' 87 ,

Washington Residency Pro-

promoted to assistant profes-

Langone, '96, is enjoying her pe-

has been appointed medical di-

gram in Rehabilitation Medi-

sor and am now the director of

diatric residency atthe University

rector of Erie County Medical

cine in 1995. Presently, he is

obstetrical anesthesia at the

of Texas and will stan in terview-

Center's ca rdiac care and telem-

an associate medical director

University of New Mexico .

etryunits. Heisa lsoanassistant
professor of medicine, division

at Whittier Rehabilitation
Hospital in Westborough , MA.

of cardiology, at UB. In this ca-

He and his wife, Kathleen ,

pacity, Smith is clinical precep-

ing soon for a general pediatric
position in

ANTHONY

LANGONE ,

ashvi lle, TN.

' 96 ,

proudly announced the birth

writes: I am currently in my
second year of my interna l

MOR G AN

tor for third-y ea r medical

of their son, Marc Daniel

medicine residency at Baylor

alumnus of UBs orthopedic

students and lectures exten-

Liguori , in july 1997.

College of Medicine. After being

residency, hand and spine

accepted by l2 nephrology

fellowship , is back home in Cajun

CYNTHIA LEBER MAN JENSON ,

programs, 1 have accepted a po-

country in private practice, hav-

writes: Mark and 1 had

sition at Vanderbilt University-

ing successfully completed two

our second child, Erica, on

a three-year fellowship with

international adoptions (one girl

january 16 , 1998. She joins

special certification in renal

from China and one from Viet-

transplantation. My wife, Susan

nam) and planning more.

sively on topics related to
cardiovascular disease.

' 92 ,

1

9

9

0

PAUL A . LIGUORI , ' 91 ,

gradu-

ated from the University of

Alexandra, now three . 1 was

P.

LORIO,

' 88 ,

Four UB Alumni Presented AMA/GlaxoWellcome Leadership Award
skills, and the Allegheny Regional
resident at the State University of New
F
Development Corporation, which
York at Buffalo School of Medicine and
our alumni of the UniHrsity at Buffalo
School of Medicine and
Biomedical Sc1ences were
presented the AMNGlaxo
Wellcome
Leadership
Award at the AMA's interim
meeting held in Dallas in
December 1997 .
The award, which was
given to only 40 recipients
nationwide this year ,
acknowledges resident
physicians and fellows
who have demonstrated a
strong commitment to their
civic or medical community through volunteer
activities. Recipients arc
given the opportunity to
participate in the Am erican Med1cal Association's
policy-making process by
attending two meetings of
the AMA Resident Physicians Sec tion (AMA-RPS ).
The obJeCtive of the
program is to encourage
involvement among community-oriented physicians

8

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and to develop the skills of
potential leaders of orgamzed
medicine . Award recipients
have their expenses paid to
attend one annual and one
intenm meeting of the AMARPS and the opening session
of the AMA house of delegates.
The four UB alumni receiving this award , and their
contributions as described b)
the AMA, are as follows:

Biomedicol Sciences.
Stephen J. Kimatian, MD '92,
cochaired ofund·
raising event for the
Children's Hospital
of Buffalo during
medico\ school. Then
while in the U.S. Air
Force, he served as
ofacilitator for teen and family support
groups and coordinated school physico\
examinations and immunization reviews.
Kimotion is on anesthesia resident at the
Hershey Medico\ Center of the Pennsylvania
State University.

Kim S. Griswold, MD '94,
volunteered os o
clinician and on
the board of
directors of Conoon
House, a home for
women who ore
reconstructing their
lives after incarceration, where she
developed o program to provide the
women with health education and
initiated o program to recruit other
medico\ residents to volunteer. In 1989,
she co-coordinated La Clinico Suyo, o free
medico\ clinic for refugees and the
uninsured. Griswold is o family medicine

hyslcla

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Martin C. Mahoney, PhD, MD '95,
serves on the board
of directors of the
Contolicion Center,
which provides
health and education
services to people
with disabilities. He
also volunteers with the Niagara Fron~er
Vocational Rehobilito~on Center, which helps
the disabled acquire and maintain voco~onol

I

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provides health core to Native
Americans with disabilities. Mahoney
is a family medicine resident at the
State University of New York at
Buffalo School of Medicine and
Biomedical Sciences.
Andrew Sherman, MD '93,
volunteers at
two local boys
and girls clubs in
Seattle that
serve under·
privileged innercity youth. He
coaches basketball year-round,
providing leadership and o positive
role model to 12-14-yeoriJ\d boys.
He is ovolunteer physician for o loco\
high school team and provides
physicals, game coverage and acute
core of injuries. He also provides
acute-core coverage for the spinal
cord-injured patients at the Veterans
Administro~on games. Sherman is o
physical medicine and rehabilitation
resident at the University of
Washington Hospital in Seattle.

an

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                    <text>�BUFFALO PHYSICIAN

Volume 33, Number 1
ASSOCIATE VICE
PRESIDENT FOR
UNIVERSITY SERVICES

Dr Carole Smnh Petro
DIRECTOR OF
PUBLICATIONS

Kathryn A. Sawner
EDITOR

StephaniC A. Linger
ART DIRECTORIDESIGNER

Alan J. Kegler
ASSISTANT DESIGNER

Lynda IIanne!
PRODUCTION MANAGER

Ann Raszmann Brov.-n
STATE UNIVERSITY OF
NEW YORK AT BUFFALO
SCHOOL OF MEDICINE AND
BIOMEDICAL SCIENCES

Dr John R. Wnght, Intcnm Dean
EDITORIAL BOARD
Dr Bertram Portm, Chair
Dr Martin Brecher

Dr Harold Brod\
Dr Linda J. Corder
Dr Alan J. Drinnan
Dr James Kanskt
Dr Barbara MaJCront
Dr Eltzabeth Ohmted
Dr Chari" Pagancllt
Dr Stephen Spauldtng
Dr Bradlq T. Tru"'
Chr"topher Adams
Dr Frankltn Zeplownz
TEACHING HOSPITALS AND
LIAISONS

The Buffalo General Hospnal
.\ftdtacl Shaw
The Chtldren"s Hospnal of Buffalo
Eric Coullly Medical Center
\&lt;!ern Health Svstem
Mtlla~d Fillmor~ llcahh System
franll Sma
:-.:iagam Falls Memorial Medical Cemer
Ro~wcll Park Cancer Institute
Ststers of Chanty Hospnal
Dennis .\1rCwcln
Veterans Affatr'-. \\'estern :\cw York
Hcahhcarc System
(()The State Cnt\Crslly of :-.:ew York
at Buffalo

Buffalo PltyStctan is publtshed
quarterly by the State umversit' of
"'ew York at Buffalo School of
Medicine and Biomedical Sciences
and the Office of Publtcatwns. It is
&gt;ent, free of charge,toalumnt, faculty,
students, resident.&lt;., and friends. The
staff reserves the right to edn all cop)
and submissions accepted for
publtcauon.

Letters to the editor,
address changes or other
correspondence should be
addressed to: The Editor,
Buffalo Physician, Stale
University of New York at
Buffalo, Office of Publications,
136 (rafts Hall, Buffalo, NY
14260. We can also be reached
by phone at (716) 645-6969;
by lax at (716) 645-2313; or
by E-mail at
bpnoles@pub.buffalo.edu

neaP Alumni and FPiends,
As "'OTED I'\ THE LAST IS UE OF THE BUFFALO PHYSICIAN, on April1
we welcomed to the university our new vice president for Health Affairs,
Dr. Michael Bernardino. Michael's experience in Atlanta in the managed
care environment will be invaluable as we face the evolving challenges
within the Western New York community. Coupled with the recently
consummated merger of Buffalo General Hospital, Children's Hospital
of Buffalo and Millard Fillmore Hospital, it is a certainty that these
challenges will multiply over the months ahead.
Spring Clinical Day has come and gone for another year and, as
usual, the event was an unqualified success. On Thursday night, the
Dean's Advisory Council joined the james Platt White Society at the society's annual dinner,
which, this year, was convened at the Center for Tomorrow. The various reunion class alumni
met at several different venues around the city and congregated at a reception Friday evening,
and again at the Saturday morning scientific program, The Aging American.
On May 22, 1998, we graduated 138 new physicians and 37 new PhD scientists at the
Center for the Arts building on the orth Campus. David Hohn, MD, president and CEO of
Roswell Park Cancer Center, spoke on the Problems, Solutions and Challenges for clinical
practice and medical research. Although many of our graduates will remain in Western ew
York, even more will continue their training elsewhere, and no doubt establish their
professional "roots" in other places around the country. Included in this issue of the Buffalo
Physician is a Match Day 1998 list of where our graduates were placed in their residency
programs. I encourage you to review this list and to contact and welcome your fellow UB
graduates who are moving into your community.
A focused visit from the LCME was completed in April and, although we have yet to hear
any official pronouncements, we believe we are on the right track. The LCME has been
concerned about implementation of several new small-group course offerings and the density
of the curriculum, particularly in the first year. Two other areas of concern were financial aid
and general student advisement. Progress has been made on all fronts (except, perhaps, for
the first-year curriculum density issue) and the alumni advisement program was recognized
as a major advancement for the school. The Alumni Association has agreed to expand the
advisement system to encompass all four years.
The school budget continues to represent a challenge, particularly as the changing
practice environment impacts on revenues centrally available for operating the school.
Philanthropy has become even more important to us and you will no doubt have already
gotten a sense of this through the various mailings you have been receiving. I hope to continue
meeting alumni "on the road,'' as it were, and taking advantage of those opportunities
whenever they arise. One purpose of these meetings is to reconnect alumni with the school.
This is more than just an effort to increase philanthropy, although many of our alumni are
actually looking for opportunities to "reinvest" in the school that gave them so much. We also
have a great deal of "expertise" among our alumni, who can be of immense help in providing
advice and counsel as we move ahead into the next millennium.

0
t/~?w:"',
.i,~~~~m MD

Dean
School of Medicine and Biomedical Sciences

Cover

I LLUSTR ·ITIO--:

B\

MICHAEL

GELEN

�Dear Fellow Alumni,
A s THE :-.:EW PRESI DE"T O F
TH E M EDI CAL A UJ M:-JI A SSOC IA TI O , I plan to continue

the good work started by our
previous presidents. Thanks
to the leadership and direction from our past president,
Jared Barlow, and the hard
..
work of john Bodkin, this
........
year's Spring Clinical Day,
titled The Aging American, was a tremendous
success. This issue of the Buffalo Phy sician contains an article on this year's Stockton Kimball
lecturer, Edward H. Wagner, MD , '65. Already,
plans are under way for next year's event, with
.
. .
.
.
-. . . -.

D.K.

M i ller

about the death of Dr. David K. Miller
(Winter 1998, Buffalo Physician). He was a great teacher and
clinician. l would like to relate to you an incident that happened
to me as a junior medical student while on my internal medicine
rotation at [the E. ]. Meyer] Memorial Hospital in 1965.
Dr. Miller was the attending on the medical service at that time.
Internal medicine was my second clinical rotation.
During one of the first days on the rotation, I was told by the
a his
and physical on a patient
resident to
for renal failure (prethe bedside, introduced
was going to perform a
me that I was about the
a history and physical on
UNIVERSITY AT BUFFALO SCHOOL OF MEDICINE AND BIOMEDICAL SCIENCES
and none yet had found an
d me to proceed. Being a
, l performed a complete
I WISH TO NOMINATE (print) - - - -- - - - -- - - - - - - - - - - - - - - -- 1ation of the nares l found
AS A DISTINGUISHED MEDICAL ALUMNUS/A.
septum. With this findi ng
had revealed granulomas,
COMMENTS (required)-- - - -- -- - -- - - - - - - - - - - - - - - - - - - ent possibly had Wegener's

..

WAS SORRY TO READ

..

Distinguished Medical Alumnus/a Award Nomination

rounds, I told the chief
tative diagnosis and that I
ained for possible biopsy.
1as ordered, nor did any of
patient's nose.
;ervice
three weeks, but in
YOUR NAME - - -- - - -- - - - - - - -- -DEGREE/YEAR - - - -- - l made weekly attending
~- Miller always treated the
SIGNATURE _ __ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ __ _ _ _ _ _ _ __ _ _ _ _ _
Attach separate sheet if more space is needed fo r comments.
medical team. He asked
Please respond by March 1 of the current academic year. ominations are rev1ewed annually .
tg you think and challeng~ was tough but honest and
wa" ~:,c:Hc:• auy uiL&lt;::Ic:,Lc:u 111 u•c. pau.:nt's welfare. During those
three weeks, this patien t was never presented to him because
the patien t has been presented so many times in the past.
Shortly after my third attending round with Dr. Miller, I
passed him in the hall and he stopped to talk to me about how
my rotation was going. I told him fine and then proceeded to tell
Medical Alumni Association
him of my findings in the patient with the nasal lesion and my
tentative diagnosis. He thanked me for telling him this and
proceeded down the hall. Figuring that my comments had again
fallen on deaf ears, l felt that I had done about as much as l could
do to convey my concerns about this particular patient.
Unbeknownst to me, Dr. Miller had immediately proceeded to the ward, demanded the chief resident come with
him, took an otoscope and performed a nasal exam. He observed
CONTINUED

ON

PAGE

2

�first year of medical school, in 1976, I attended the
graduation ceremonies.! was appalled that the graduates, after four very difficult years of medical school
training, wore basic black gowns and the "square
hats." I had imagined that the graduates would be
attired in very elaborate gowns, befitting their acwhat I had described on my physical exam and he personally
complishments-a
gown similar to the one the dean wore.
called theE T attending and requested an immediate biopsy
During
my
fourth
year of medical school, I pursued the
of the lesion. A biopsy was performed that day which
of
a
more
elaborate
graduation gown. The dean's gown
idea
revealed granulomatous inflammation, with necrosis, comstood out in my mind. After receiving permission from the
patible with Wegener's granulomatosis.
dean' office to investigate the matter, I contacted several
othing more was ever said to me about this, since I had
gown companies and obtained several different designs and
rotated to a different service. Over two months later I was
prices, the most beautiful design being the replica of the
asked to attend the Medical Grand Rounds. At the grand
dean's
gown. The class of 1979 met and voted to make the
rounds a case of Wegener's granulomatosis was presented.
dean's
gown the official gown of graduation.
After the presentation, Dr. Miller stood up and stated that
The company hired to produce all the necnumerous physical exams had been performed
essary gowns, completed the order in time for
on this patient over the previous six months
Your letters are
our graduation. I had fulfilled my dream. The
prior to his diagnosis and that the patient had
welcome. Please submit
excitement and anticipation of wearing these
gone undiagnosed until a junior medical student
to Editor, Bullalo
elaborate gowns permeated the entire class.
had made the diagnosis by noting the nasal
Physician, 136 Crofts
However, the week the gowns were to be
lesion. l was then introduced as the person who
Hall,
University
at
delivered
for our ceremony, the nation's truck
had made the diagno is.
Buffalo,
Buffalo,
NY,
drivers
decided
to strike. The gowns were rell did not choose to go into internal medicine,
14260;
fax:
716-645egated
to
a
warehouse
until the strike ended.
although Dr. Miller tried hard to convince me to
Ironically, my classmates and I graduated in
2313; or E-mail:
choose a career in this discipline. l chose a career
the same basic black gowns and "square hats" of
bpnotes@pub.buffalo.edu.
in surgery and did a general surgery residency and
our predecessors. However, the fact that future
We reserve the right to
then a fellowship in surgical oncology at the
classes wear the gown that eluded my classmates
University oflllinois Hospital in Chicago, Illinois.
edit letters for length
and
me makes me somewhat envious, but also
I cannot tell you what effect this incident had
and style.
very
glad the issue was pursued. It is a gown
on my medical career. However, it instilled treof the wearer and the ceremony.
worthy
mendous confidence and taught me that we
should stand by our convictions and not just accept the status
quo. As a clinical professor and practicing physician, I have
tried to emulate Dr. Miller's skills as a teacher and clinician,
and I will never forget him. The medical community has lost
a stellar physician and colleague.
ROBERT M. BARONE, MD, '66, FAC
San Diego, California

. jOSEPH GAGLIARDI, MD, MA, '79
Columbia, Maryland

Editor's

Note

The dean's gown described by Dr. Gagliardi was originally designed
in 1971 by the late Robert L. Brown, MD, '44, to commemorate the
125tll annivers01y of the founding of the school of medicine. Dr.
Brown was associate dean of UB's school of medicine, as well as
medical school archivist and associate professor ofmedicine emeritus.

Seams from
the Past

Due to the efforts
GRAD

ATED

FROM

the University at Buffalo School of Medicine in 1979. Every
year I read with interest your review of the
medical
school's
graduation. l would
like to share with you the
origin of that very handsome graduation gown.
At the conclusion of my

of the Class of
1979, all students
graduating since
1980 have worn
the "dean's gown."
Pictured is Joell.
Sebastien, Class of
1998.

J

"'
:&gt;
"'z
~

z

0
0

�VOLUME

33 ,

NUMBER

1

SUMMER

Elegant Solution to a
Complex Problem

Merger Final

4

8

NEWLY MERGED

HEALTH SYSTEM-

20

1998

Physicians Reaching
Out to Students

UB ALUM AND PROFESSOR

U B

MEDICAL ALUM I

INVENT LASER TARGETING

ASSOCIATION BEGINS

SYSTEM USED WORLDWIDE

NEW MENTORING PRO-

by S. A. Unger

GRAM FOR STUDENTS

Photo by K. C. Kratt

by Nicole Peradotto

CHALLENGES AND

OPPORTUNITIES
FOR UB

by S. A. Unger
Illustrated by Michael Gelen

Alumni

Medical School

SPRING CLINICAL
NATIONAL RESIDENCY
DAY ,

"THE AGING

MATCHING PROGRAM
AMERICAN"
RESULTS LISTED
EDWARD H. WAGNER,

photos by Frank Cesario

Research

STOCKTON KIMBALL
* REDUCING MULTIPLE
LECTURER
COMMENCEMENT 1 9 9 8 ,

A

BIRTHS

by Scott Thomas

TIME TO CELEBRATE

* PROSTATE CANCER ,

photos by Don Heupel

ESTROGEN LINK

Class Reunions

* HYPOXIA STUDIED

* TALLER,

P HOTO

BY

NOT HAPP IER

�Newly Merged Regional Health System
Presents Challenges and Opportunities for UB

. - - - - - - . HE LO 'G-A:"\TlC IPATED MERGER OF Buffalo General Health System,

Children's

Hospital of Buffalo and Millard Fillmore Health System was announced on
Aprill, 1998. After nearly two years of extensive study, planning, legal work
and governmental reviews, the merger came to fruition, significantly
reconfiguring the Western

ew York health-care delivery system.

Making the announcement was john E. Friedlander, president and chief executive officer
of the newly merged regional health system, which has temporarily been named CGF Health
System. "Thanks to the efforts, spirit of cooperation and commitment by a great many people
in all of the involved organizations, we have made history today because the face of health
care in Western

ew York has been changed forever in a very positive way," he said.
ILLUSTRATION

BY

MIKE

GELEN

�BY

Friedlander also paid special tribute to the boards, physicians and
internal leadership of Millard
Fillmore, Children's and Buffalo
General for their "extraordinary vision and strong desire to work together to create a dynamic , new ,
value-driven health-care system for
the community and region. "
Facilities included in the merger
are Buffalo General, Millard Fillmore
Gates, Millard Fillmore Suburban,
Children's and DeGraff; four longterm care facilities; a number of home
care services and approximately 50
service locations in five of Western
ew York's eight counties. In all, the
merger brings together 2,200 physi-

S

.

A

.

UNGER

cians and 12,000 employees under
the CGF Health System.
"As an organization, CGF is committed to assuming a leadership role to
promote the health of our community
and, in doing so, improve the overall
quality of life for everyone we serve,"
said Friedlander, who emphasized that
as part of its mission, CGF is committed to excellence not only in service,
but in education and research , as well.

The UB Connection
Because all three of the larger hospitals
involved in the merger-Buffalo General, Millard Fillmore and Children 'shave teaching and residency programs
with the University at Buffalo's School

of Medicine and Biomedical Sciences,
the future place of academic medicine
within the CGF Health System has
been the focus of much attention and
concern within the UB community. In
addition to ways in which the new
merger will affect the school of
medicine's primary mission of educating future physicians, there is also a
complex financial relationship between
the school and the hospitals involved
in the merger. As john R. Wright, MD ,
interim dean for UB's School of Medicine and Biomedical Sciences, explained last winter in a message to
Buffalo Physician readers, "The state
budget provides only 13 to 14 percent
of [the medical school's] annual ex-

�Newly

Merged

Regional

Health

System

penditures, matched by approximately school," he adds. "It would not be in
by university administrators, led by
the same percentage from extramural- our best interests to be dealing with a
Michael Bernardino, MD, the Universponsored research programs. Since weak, floundering, constantly volatile
sity at Buffalo's new vice president for
hospital support, which also includes delivery system."
Health Affairs.
the residents' salaries, accounts for apost of these prinThis is a perspective shared by the
proximately 23 percent of total expen- business community at-large, Wright
ciples are not conditures and the practice plan, an addi- feels. "I think the business community
tentious, but reflect
tional 41 percent, over 60 percent of sees health care as playing a major role in
mutual goals the
our funding is derived through the the rebirth of the Western ew York
university would
health-care delivery system."
support, according
economy. The University at Buffalo is
ln an interview several weeks after arguably the largest employer in the reto Wright. "However, there are some principles that
the merger was announced, Wright ex- gion and probably represents--if you
may not completely or accurately deplained that while the merger does included faculty, staff and students-the
present clear-cut challenges for the uni- largest group of health-care consumers.
fine the university's position on what
should be included or excluded in an
versity and the medical school, it pro- And recently, a number of health-care
affiliation agreement. It will be over
vides significant opportunities, as well. manufacturing companies have sprung
those issues that the agreement, in its
In order to effectively balance the up in the region and, although it's not
present form, will be subject to negothreat of challenges with the promise often a well-appreciated fact, this is a very
tiation as we begin this process," he
of opportunities, Wright feels it's im- promising local industry. So, there's an
remarks.
portant to step back and view the opportunity at this time for the univerWright outlined four benchmark
merger in a context that includes as sity, the health-delivery system and priconcerns the medical school will put
broad a vision as possible for the future vate industry to work together to improve
of health care in our region.
forth in its negotiations with CGF. The
the economic climate of this region."
first, he says, is that "We need to be
"I think it could be said that the
ln addition, Wright foresees impliable to control the educational envidriving forces behind the formation of cations of the merger that could
ronment for our students and resithe CGF Health System have been com- provide other, more specific opportudents, and that level of control clearly
munity leaders as much as the individual nities for the medical school. "We will
overlaps with CGF's equal desire to
hospitals themselves. This merger is an have a chance to consolidate the medihave control over the medical services
effort for our community to determine cal school's programs and to develop a
it provides and the physicians who
its own future bymaintainingsome local more focused, less distributed clinical
provide them."
programs,"
he
explains.
base
for
these
control over the provision of health-care
Secondly, he says, "We are a comservices in an environment where com- "There will also be opportunities to
munity-based medical school and there
mercial enterprises from outside our re- organize our clinical faculty and pracis the desirability, in fact necessity, for
gion could come in and determine it for tice plans into a more cohesive, cenus," he says.
ew York
State is cur"I think the business community sees health care as playing
rently not a
particularly
full-time faculty to work side-by-side
hospitable environment for for-profit tralized operation-something that has
with volunteer faculty. " As a result, he
hospitals, according to Wright, who been missing in the very distributed,
adds, "There needs to be different insays that could change. "Clearly, this community-based medical system that
reorganization of health care in our has been in place in Buffalo."
centives and constructs for each group,
community is a proactive commitment
and it is critical that CGF be able to
to plan for the future and to gain con- Challenges and Obligations
create an environment that fosters coltrol over costs and administrativestruc- Following announcement of the
laboration among physicians. "
ture now.
merger, CGF presented the medical
Thirdly, the medical school has a
And of course what's healthy for the school with a Principles of Affiliation
need, as well as an obligation, to concommunity is healthy for the medical Agreement, which is being reviewed
tinue its relationship with health-

a

�delivery systems not included in the
CGF system, and the affiliation agreement cannot in anyway jeopardize
these long-standing relationships.
"We have an important working relationship with Roswell Park [Cancer
Institute], Erie County Medical Center, the Veteran's Administration system and the Catholic system that we
simply cannot and will not abandon ,"
Wright states. "We cannot work exclusively with the CGF Health System. That would not be good for us ,
nor for the community. "
And, finally , "The relationship between the university and CGF must
be financially sound, " Wright says.
"So , it's a symbiotic relationship in
which the health and well-being of
both entities is absolutely essential to
the entire process. "

"Roswell Park is clearly one of the
centers of excellence that is already established in Buffalo and, therefore, is key
to the goal of having other such centers
because it already has as its mission the
cultivating of a referral base beyond this
region, more so than any other facility in
our area ," Wright explains.
This interest in drawing individuals
from outside the region to a center of
excellence relates back to the business
community's goal of ensuring that
health care in Western ew York
remains a viable economic force and
one that can form a base for revitalization, explains Wright, who emphasizes
the integral role academic medicine
would play in the development of such
centers. "I am convinced, " he says,
"that in most, if not all , centers of
excellence , an academic presence
ensures that the center is going to
continue to grow and develop more
innovative approaches to treatments
compared to a facility that is simply
a highly skilled practice site that
does not have the constant influx
of new information that an academic
affiliation provides. "

that we have a full-time vice president
with expertise in these various areas ,"
he adds , referring to Bernardino, "we
feel dialogue will open up and the
faculty's comfort level will increase."
Wright emphasizes, too , that how
the health-care delivery system in Buffalo takes shape in the months and
years ahead will involve choices the
community will need to make, as well ,
and will not be limited to what the
university, area hospital systems and
physicians determine to be the best
course. '·For example," he says, "the
question could be asked of the community: 'Do you want a medical school?
And if you want a medical school, do
you want a good, bad or indifferent
school?' I would assume the answer is
'Yes, we want a medical school, and we
want it to be an excellent school."'
iven the current comCenters of Excellence
plexity of Buffalo's
The ultimate goal of such a symbiotic
health-care delivery sysrelationship between the university and
tem, finding a middle
CGF is the development of "centers of
ground that best repreexcellence" that would not only serve
sents the collective needs
the Buffalo community, but would result
of the population of our
in a referral base from outside the region,
region-not just the needs of the varaccording to Wright. The idea of estabied entities that provide the care-will
lishing a network of centers of excel- Opening up Dialogue
be a challenging process but one Wright
lence has been repeatedly floated about Wright acknowledges that the prois optimistic about. "Working out how
the Buffalo medical community over longed merger process has been very
health care will be best delivered in our
the past few decades, but has gained stressful for medical school faculty, but
community will not be a slam dunk;
there is a lot
of work to be
major role in the rebirth of the Western New York economy...
done," heconI
cedes. "We're
. !. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .~ going
to go
momentum in recent years as a result of also points out that it has been difficult
through some pain, we're going to have
market pressures leading to , among for the university to take a proactive
differences of opinion, and we will have
other things, the CGF merger. Under role in clarifying the ramifications of to work things out over time. For the
the centers-of-excellence model , a such a merger until the merger itself long run, we need to look at how we can
particular facility would complete a was formally in place. 'The university
deliver health care in our community in
high volume of specific procedures for couldn't hammer out an affiliation
a way that not only helps assure the
treatment of defined conditions, such as agreement with a merging system while
viability of the medical school, the unicancer or heart disease, in order to con- there was still a possibility it would
versity, and area hospitals, but in a way
trol costs and assure the highest possible fail ," he explains. "However, now that
that helps ensure the viability of our
quality due to its focused expertise.
the merger has in fact occurred and now
entire community." +

�MICHAEL K . LANDI , MD , LEFT, AND ROBERT M . LIFESO , MD , WITH
DUAL TARGETING RADIATION SYSTEM THEY INVENTED .

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UB ALUM AND
PROFESSOR INVENT
LASER TARGETING
SYSTEM

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Today, the product they
developed, called the
DRTSTM Platform (for Dual
Radiation Targeting System), is being manufactured
in Orchard Park, ew York,
and sold throughout most
of the world. While application for the DRTS Platform was initially aimed at
the orthopedic field, other
uses for it are rapidly becoming apparent as the innovative tool makes its way into the hands of skilled clinicians in other fields , from oncology to neurology.
The system, which received Food and Drug Administration approval in September 1997, is being marketed by Ml RAD Inc. , whose chief executive officer,
William Burns, was named Inc. magazine's 1993 Entrepreneur of the Year in ew York State.
Fl\lll\1

a research project to find a
better way to do this. "
This was a project for
which Landi was ideally
suited. Prior to entering
medical school to pursue
an interest in biomedical
engineering, he had completed a degree in electrical
engineering at the University at Buffalo. Before coming to UB , he worked for several years at a company in
Los Angeles that developed software for projects requiring advanced radar systems. Earlier, he had served
in the U.S. avy, working with guided missile weapon
systems on board a destroyer.
Lifeso, who is director of the Spinal Cord Injury Unit
at Erie County Medical Center and clinical professor of
orthopedic surgery at UB's school of medicine, did not
have Landi's engineering background; however, he did
have a strong interest in laser technology and its potential application to medicine.
When Landi approached Lifeso about working on
the research project he had proposed, Lifeso was excited to learn of the young medical student's training in
engineering and immediately saw the fit. "He talked to
me about a concept he had of combining X-ray with
laser light and how that might provide a sort of guidance system for surgical procedures," Landi says.
After further discussions, Landi decided this was a
concept well worth pursuing and he went to work for Lifeso
during the summer between his first and second year of
medical chool, devoting himself to taking a roughly formulated idea and turning it into a marketable product.
"Once I fully understood the problem, I saw that
what you needed was a way to mark a surface point of
entry that would not interfere with the operant field
and give an axial alignment to intersect with a subsurface target. And a laser pointer made the most logical
sense," says Landi, who today is a neurosurgery resi-

\ BITTI· Ii \\'\)Til Dll Tiii'-

The story of how the careers of these three men
converged at the point of a laser beam began in the fall
of 1990, when Landi was a first-year student at the
University at Buffalo School of Medicine and Biomedical Sciences. "I was assigned Dr. Lifeso, an orthopedic
surgeon, as a preceptor," he recalls. "The first time I
met him was at a morbidity and mortality conference
where the previous month's cases and complications
were presented. One complication discussed involved
a nun who had fallen out of bed and fractured her
femur after an intermedullary rod placement in which
the distal-locking screws were inserted incorrectly.
Dr. Lifeso explained that this was a common problem-that external targeting devices that are supposed
to point you toward the region where you need to
make the incision and place the screws, weren't that
accurate and when done under X-ray imaging required
excessive radiation exposure to the patient and surgeon. He then asked if anybody was interested in doing

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dent and a research instructor in UB's Department of
Cn \"II jl B.\ C1111l E
Electrical and Computer Engineering. "The most diffiWilliam Bums was the former president and chief execucult problem was developing a way to make the laser
rive officer ofMatrx Medical Inc., North America's largest
light coincide with the image that you saw from the
manufacturer and distributor of emergency medical prodX-ray. Once I figured out how to do that, the device
ucts. "Bill Burns provided the entrepreneurial brain
came together very rapidly ," he says.
power we needed," says Lifeso, who describes his first
Figuring out how to do this "just required a lot of
few years working with Burns as "a crash MBA course."
geometry," according to Landi. "Basically, what I came up
Securing the intellectual property rights for the dewith was a system that identifies a line of radiation from
vice was obviously a high priority and little time was
the X-ray source to the detector; positions a laser beam so
wasted. In May 1993, the first patent for the device was
that it's co-linear with that line of radiation; and puts a
awarded to Lifeso and Landi and assigned to the Reradiopaque target symbol- a cross hair- on that same
search Foundation, State University of ew York at
line of radiation so that its image on the TV monitor
Buffalo. In May 1996, Burns and the two inventors
represents a point on the line that the laser indicates."
formed a company called MI RAD (minimum radia"Once Mike began building prototypes," Lifeso says,
tion) to market the DRTS
"it became clear to us that the real problem we were facing
Platform and today the
was finding the center of the X-ray beam, and that's where
BH( l.\ll .\PPLH:.\Tit~~~
company employs 25
his expertise came in. He designed a collator that is key
people, including six
.\cno~~ jf.\:-~r
to the device being able to correlate the flu oro image of
engineers, regulatory exthe screw placement site, as viewed on the TV monitor,
, 'PECL\LTIE:-perts and two patent
with a precise point on the
patient's anatomy. ''
Throughout the summer,
Landi worked on the project at
home with materials he and Lifeso
were able to obtain using their
own resources. "The first prototype was made using a mirror
from a bird cage and PVC pipe
from a hardware store," Landi
recalls. "And the second model
was built using a flashlight housing and a dental mirror. "
By the end of the summer, Targeting brain tumors during perioperative localization.
Landi had designed and built a
device that was remarkably sophisticated and someattorneys. In late 1997,
thing the two inventors were fairly confident was a
the University at
valuable innovation if they could get it in the hands of
Buffalo invested in
someone who knew how to market it. Essentially what
MINRAD , taking up the
they had developed was a system that would allow a
largest
equity position it
surgeon to use the fluoroscope to visualize and locate a
has
ever
held in a startdeep structure, turn off the X-ray radiation and still have
up company.
accurate guidance and position information relative to
"This was an opporthat deep structure. Using their device, a surgeon would
tunity for the universimply place his or her drill tip on a patient at the precise
sity to invest in a strong
spot indicated by the laser (e. g. , as pointing to the hole
start-up company, bein the intermedullary rod) and drill along the axis
ing led by an excellent
indicated by the beam.
entrepreneur with an
"Once we had gotten that far with the device, we started
exceptionally good
to realize how little we truly knew about what to do with
technology in a promthe thing," Lifeso says. "Because we were both affiliated
ising market, " says
with the university, we went to the Office of Technology
Daniel Massing, former
Transfer, and they put us in touch with Bill Burns."

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�director of UB's Office of Technology Transfer.
dent and general manager. "The technology patented
In cases where UB has patent rights on a technology,
by Drs. Lifeso and Landi is a very elegant solution to the
the university traditionally receives an up-front licenscomplex problem of aligning a visible laser guidance
ing fee from the company commercializing the techwith a selected portion of the X-ray beam of a fluoronology , according to Massing. In this instance, in lieu
scope. The simplicity of the solution they came up with
of the licensing fee , the university will receive equity in
means that it is inherently less expensive to manufacMI RAD based on its interest, which consists of foundture and less costly and complex to maintain after
ing shares and subsequent stock purchases equal to 4. 7
installation. You can't help but feel good about a project
percent of the fully diluted interest. In turn, UB's
that is this straightforward to design and manufacture,"
license and patents on the DRTS were beneficial to the
Me eirney says. "After 30 years' experience with simicompany as components of the prospectus document
lar projects, I've seen both sweet and sour solutions.
for raising funds , Massing explains. "The opportunity
This is a sweet one. "
to take equity in a start-up company that is commerll11 \II\ 1, I\ II\ ~ f.\1 ,\I' I' L II \Till\"
cializing research developed in our own laboratories is
consistent with a national trend by universities," he
Sweet also is the fact that other applications for this
notes. "Once the stock is sold, the return to the univerdevice are rapidly developing, which make it more
sity of an equity position can be significant, often
versatile than its inventors originally intended it to be.
exceeding what would result from the license income
In oncology, the device is proving to be ideal for
generated by royalties. "
performing minimally invasive biopsies oflesions than
And the return to all investors does indeed look
can be visualized with X-rays. This use of the system
promising. According to Burns, surgical procedures
could also translate into significant improvements in
guided by fluoroscopy account for about 10 percent of
the accuracy of deep tissue biopsies done on breasts,
all operations performed worldwide. "There are about
livers or spleens, some 20 percent of which currently
90,000 fluoroscopes currently in use around the world, "
produce false negative readings. " ot only will you be
he says, "and I think the market potential for the
able to improve accuracy, but you will also be able to
MI RAD device could reach $130 million, plus anreduce the patient's exposure to radiation as well as his
other million for disposable accessories , such as surgior her discomfort because you can hit the target on your
cal drapes and biopsy needles.
first attempt, without having to manipulate the needle
On September 24, 1997, two weeks after it received
under fluoro , something that can be especially painful
a notice of approval from the FDA for the DRTS,
during bone or vertebral biopsies," explains Landi.
MI RAD launched
Other promisthe device at the
ing applications for
annual Meeting and
the system are in
Exhibition of the
neurosurgery ,
·To! C.\'i.T IIELI' BI'T FEEL mon \Bili"T ,\ l'!lO.JECT TIL\T I.
British Orthopaewhich especially
dic Association in
interests Landi
Cardiff, Wales. Earsince this is the
lier, the DRTS had
field he chose to
.\HEll :~1) YL\H&lt; E\I'EHIE'if:E \\ITII SI\IIL.\Ill'llii.Ji':CT:--. I\ E
been approved for
pursue following
sale by Europe 's
his graduation
'EE'i BoTH s\\EET \'ill ·,wn 'ilLlllil:\ . Tm·.; '"' .\ s\\"EET ti:\L.".
FDA counterpart,
from
medical
and MI RAD has
school in 1994.
since signed a 10"We're using the
year $83 million
DRTS to target
agreement with Atmos Healthcare, to distribute the
intercraniallesions prior to brain surgery. We use it as
DRTS in 16 countries in Europe. Recently, a 34
a frameless stereotactic system to localize lesions in a
million contract was signed with an Asian distributor.
3-D space, as opposed to the system currently in place,"
Currently, MINRAD i hoping to produce 400 syshe explains, referring to the standard stereotactic protems a month at its Orchard Park facility, with a sale
cedure that involves bolting a rigid frame onto a patient's
price of $4,000 for each. The only other systems that
head, then placing him in a CT scanner to obtain a
come close to competing with the DRTS are priced at
three-dimensional picture of a lesion. "What most
about $300,000 and are much less accurate than it,
neurosurgeons will tell you is 'get me there and I can
according to john Me eirney, MI RAD's vice presiCONTINUED
ON
PAGE
31

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�BY

LINDA

J.

CORDER.

PHD,

CFRE

Dreams Woi1h Weaving
CREAT I NG A TAPESTRY FOR THE SCHOOL O F MED I C I N E A N D B IOMED ICAL S CIENCES

'

HY DEVELOPMENT?" This is a frequent question, especially when I first meet someone unfamiliar with the day-to-day work of a medical school
development officer.
Weaving is my favorite metaphor for development. In weaving a tapestry or a rug, the details of the
background work are invisible, yet a successful outcome is
impossible \Vithout careful attention to preparing the loom,
securing the strands of the wrap, filling and threading the shuttle
and deciding on a general pattern. Similarly, in coordinating
development efforts for the School of Medicine and Biomedical
Sciences, m; background activities are largely invisible.
However, planning, setting priorities and having sufficient resources to support the development program are as
important as the loom, which provides the mechanism that
makes weaving possible. Maintaining good records and the
systematic gathering of additional information on alumni and
friends are analogous to the warp, as appropriate research
supports all productive development. Consistent and thoughtful communications become the weft, the strands or threads
by which all other elements are linked together.
In addition, it is necessary for the development officer to
review constantly the current dreams and priorities of the
institution, always in light of its stated mission. By talking with
individuals within the school, who guide key aspects of the
academic environment, I can begin to conceptualize proposals.
At the same time, I identify prospects who might be
interested in contributing to the realization
of those dreams. In this manner, general
patterns for the desired institutional outcomes are determined; case statements for
specific projects can then be written.
Patience is paramount. On some days, no
visible progress is made. On others, it is
necessary to alter the pattern as the fabric
takes shape. Occasionally, and with great
patience, rows of weft must be carefully undone in order to accommodate changes in the
original plan. Colors must be matched and
complemented and, at times, a different yarn
or thread is necessary, requiring skill in integrating loose ends into the overall design.
A development officer's efforts call for the
same type of sensitivity and flexibility as
specific fund-raising projects evolve. The
interests and dreams of individual prospects

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need to be melded with institutional priorities.
Sometimes, potential donors will have another (or little)
philanthropic interest or the timing is not quite right. Some
reworking of original designs or finding other donors for a
particular purpose then becomes necessary. Picking up and
weaving in loose threads- by being aware of prospects'
family situations, responsibilities and goals-arc integral to
assisting others in their creative gift planning.
Both weaving and institutional development involve longterm commitment. Woven fabrics take shape slowly. The
matching of donor interests with specific programs or individuals on campus (along with ascertaining '·the best" overall
gift planning) is a time-consuming activity. As with all
relationships, this type of involvement requires nurturing
and the time to grow.
In both development and weaving, some motifs may
appear repeatedly (i.e., scholarship endowments or endowed
chairs, funded by bequests or with trust proceeds). Occasionally, a truly unique design emerges (perhaps a new interdisciplinary research center, complete with "cutting edge"
technology). Variations are constrained only by the limits of
human imagination and the resources and materials at hand.
Not only is considerable time required for the process, but
many results are primarily for posterity, lasting long beyond
the lifetimes of those from whom the funds and ideas flowed.
Thus, in some sense, each completed gift to the school is like
a work of art. It is meant to inspire-and to be used and
valued by-future generations as well as by those
present!) living.
As a development officer, 1 remain essentially
invisible to the vast majority of people who -..viii
ultimately benefit from my work. Nevertheless, I
am content to recognize "my mark" in the "final
product," just as weavers feel a close affinity with
the pieces they have created. It is the "dream
become real" that remains long after each item
becomes a part of the total fabric of the institution.
I chose to be a development officer because it
satisfies me to be a weaver of dreams-especially
when they come true.
1 chose UB because of its unique history-and
because it has dreams worth weaving . . . +

Summer

Lyn Corder, PhD, CFRE, is associate dean and director of
Development. She can be contacted at 716-829-2 773, by
fax at 716-829-3395 or on E-mail: ljcordn@buffalo.edu

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~

I

PH O T O S

B Y

FRAN K

CESARI O

Carol Chen lntcma/ Medicine,
Loyola Um,·ersit) Medical Center,
Maywood, IL
Connie H. Chen Internal Medicine,
Barnes-jewish Hospital ,
St. Louis , MO
Bonnie Cheng Internal Medicine,
Hospital of the Uni\ ersity of
Pennsylvania, Philadelphia, PA
Peter Cobb Family Practice,
Columbus Family Practi ce Cem er,
Columbus, GA
Seth Cohen Internal Medicine,
UMDNj-R.W . johnson ,
Piscataway, J
Jeanine Cooley Pediatrics,
Children's Hospital , Philadelphia, PA
Pamela Crowell Family Practice,
niversity• of Southern Florida ,
College of Medicine, Tampa, FL
Michael Cummings Psycltially ,
S l\Y/Buffalo Graduate MedicalDental Education Consortium,
Buffalo, NY
April Cyr Family Practice,
Memorial Hospital , Pawtucket, Rl
Gul Dadlani Pediatrics, SUNY/
Buffalo Graduate Medical-Dental
Education Consortium ,
Buffalo, f\iY

Emily Aguilar Pediatrics, Orlando
Region Healthcare System ,
Orlando. rL

Eric Bonenberger Ortltopedics,
St. Luke's Medical Center,
C leve land, OH

Kristen Andresen internal
Medicin e, Unt\ ersity of Rochester,
Strong Memorial Hospital,
Rochester, l'\Y

Lori Bowman Pediatrics, SUNY!
Buffalo Graduate MedicalDental Education Consortium, Buffalo, ·y

Luna D. Bailey Sw·ge•y (Prelim. ),
S NY/Buffalo Graduate MedicalDental Education Consortium ,
Buffalo, NY; O!ola•yngolog) ,
SUNY/Buffalo Graduate MedicalDental Education Consortium ,
Buffalo, '\JY
Leslie Barr FamiiJ Praclice,
SU Y/Buffalo Graduate MedicalDental Education Consortium ,
Buffalo. :\JY
Stephen Bekanich Fami!J
Practice, University of lJtah
Affiliated Hospnals, Health SCience
Center, Salt Lake City , UT
Eric Bluman Orllwpedics , Rhode
Island Hospital, Brown University,
Providence , Rl
Yvonne Bobek Pediallics, Medical
College of Virginia , Richmond, VA

Richard Bremer

Internal Medicine,
Medical College
of Virginia ,
Richmond , VA
Jennifer Bulger

Family Praclice,
St. Vincent Health
Center, Ene , PA
Robert Burns Pediatrics,
SU Y/Buffalo Graduate
Medical-Dental Education
Consortium, Buffalo, '\'Y
Therese Caligiuri Internal
Medicine, S NY/Buffalo Graduate
Medical-Dental Education
Consortium, Buffalo, NY

Jonathan
Pediatrics, SU
Buffalo Graduate
Medical-Dental
Education

�························································································•

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Left to right. Jeanine M. Cooley congrotuloted; Christopher P. Schaeffer gets o big hug of support; Nnenno Okereke, Luno D. Bailey, Sophia Streete ond Jonathon Daniels shore results.
MaryAnn Dean Psychiatr), SU Y/
Buffalo Graduate Medical-Dental
Education Consortium, Buffalo, NY
Claudia Deyoung Intemal
Medicine, orth Shore University
Hospital, Manhasset, Y
Stacey Dimartino Psychiatry,
SUNY/Buffalo Graduate MedicalDental Education Consortium,
Buffalo, Y
Vamil Divan Internal Medicine,
Mt. Sinai Hospital, Elmhurst, Y
Jane Dopkins Obstetrics and
Gynecolog}, University Hospital,
Cincinnati, OH
Jason Ehrlich

Intenral Medicine,
North Shore
Universit) Hospital,
Manhasset, Y

Andrew Esch Internal Medicine
(Prelim .), isters of Charity
Hospital, Buffalo, NY; Physical
Medicine and Rehabilitation, SUNY/
Buffalo Graduate Medical-Dental
Education Consortium, Buffalo, Y
Timothy Fallon Surge') (Prelim.),
SUNY/Buffalo Graduate MedicalDental Education Consortium,
Buffalo, Y
John Fanton Pediatr-ic Psychiatr) ,
Rhode Island Hospital,
Brown University,
Providence, Rl

Left to right:
Jeffrey Richman, Mei Y.
Wong, Jose Macedo, on
enthusiastic guest ond
Li Zeng celebrate
their future.

Charles J. Fetterman Internal
Medicine (Prelim .), S NY/Buffalo
Graduate Medical-Dental Education
Consortium, Buffalo, Y; Ophthalmology, SUNY/Buffalo Graduate
Medical-Dental Education Consortium, Buffalo, . Y
Donald Flihan urgery (Prelim.) ,
SUNY/Buffalo Graduate MedicalDental Education Consortium,
Buffalo, Y
Richard Gayle Psychiatry, Long
Island Jewish Medical Center,
New Hyde Park, Y
Thomas Gergel Famil) Practice,
Hinsdale Hospital , Hinsdale, IL
Robert E. Gerstenbluth Urology,
Case Western Reserve University,
Cleveland, OH
Youssef Ghaly Family Practice,
Mountainside Hospital, Montclair, "lJ
Hari Gopal intemal Medicine
(Prelim .), Wilson Memorial
Regional Medical Center, United
Health Services, Binghamton, Y;
Diagnostic Radiology, SU Y
Syracuse Health Science Center,
Syracuse, NY
Christine Gordon Pediatrics,
St. Luke's-Roosevelt Hospital
Center, New York, Y
Lisa Green Medicine/Pediatrics,
SUNY/Buffalo Graduate MedicalDental Education Consortium,
Buffalo,. Y
Carrie Greenberg AncsthesiolOg)-, The New York Hospital ,
ew York, Y
Alejandro Gruneiro Surgery ,
Southern Illinois Uni,·ersity,
School of Medicine, Springfield, IL
Rachna Gupta Internal Medicine,
Uninrsity of Maryland Medical
Center, Baltimore, MD

Bryan Hanypsiak Orthopedics,
George Washington University,
Washington, DC
Michael Hassett lntemal
Medicine, University of Rochester,
Strong Memorial Hospital,
Rochester, NY
Lisa Heichberger Family Practice,
Hamot Medical Center, Erie, PA
Scott Helsley lntemal Medicine
(Prelim.), SU!'\Y/Buffalo Graduate
Medical-Dental Education
Consortium, Buffalo, Y;
Anesthesiolog_\ , Duke University
Medical Center, Durham, C
Michael Herbowy Internal
Medicine, SU. Y/Buffalo Graduate
Medical-Dental Education
Consortium, Buffalo, NY
Aaron Hoffman urgery , ew
York Methodist Hospital ,
Brooklyn, 'Y
Steven Horn Internal Medicine,
SU Y/Buffalo Graduate MedicalDental Education Consortium,
Buffalo, NY
Calogero Ippolito lntenral

Medicine, SU 'Y/Buffalo Graduate
Medical-Dental Education
Consortium, Buffalo, NY
Dana Jandzinski Surgery (Prelim) ,
St. Joseph Hospital, Denver, CO
Peter Janes Medicine/Pediatrics,
S "JY/Buffalo Graduate MedicalDental Education Consortium,
Buffalo, Y
Theresa M. Jarmuz Otolar)ngology,
Emory University, Atlanta, GA
Michael Kane famil) Practice,
U Y/Buffalo Graduate MedicalDental Education Consortium,
Buffalo, NY
Lawrence Kanner Internal
Medicine, orth Shore University
Hospital, Manhasset, Y

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encourage you to
review this list and to
contact and welcome
your fellow UB

Judith Kim Pediatrics, SU Y/
Buffalo Graduate Medical-Dental
Education Consortium, Buffalo, Y
Paula Kocialski Psychiatry ,
SU Y/Buffalo Graduate MedicalDental Education Consortium,
Buffalo , Y

David Montesanti Internal
Medicitre (Prelim .), S NY/Buffalo
Graduate Medical-Dental Education
Consortium, Buffalo, Y; Ophthalmology , SUNY/Buffalo Graduate
Medical-Dental Education Consortium , Buffalo, NY

Colin Powers Surgery, SUNY/
Buffalo Graduate Medical-Dental
Education Consortium, Buffalo, NY

Anne Marie Reynolds Pediatrics,
S NY/Buffalo Graduate MedicalDental Education Consortium ,
Buffalo , Y

Jennifer Lee lntenwl Medicine,
niversity of Rochester, Strong
Memorial Hospital , Rochester, Y

Bennett Myers lntenwl Medicine
(Prelim.), Duke University Medical
Center, Durham, NC; eurology ,
Duke University, Durham , NC

Anthony K. Rice Family Practice,
Womack Army Medical Center,
Ft. Bragg, NC

Sandra Leni Internal Medicine,
SU Y/Buffalo Graduate MedicalDental Education Consortium ,
Buffalo , Y

Kristin Nesbitt Orthopedics,
Henry Ford Health Science Center,
Detroit, Ml

David Lin Internal Medicine,
niversity of Michigan Hospital ,
Ann Arbor, Ml
Neil Lipke Surgery (Prelim .), ew
York University Medical Center,
New York, Y; Anesthesiology,
ew York University Medical
Center, ew York , Y
Jose Maceda Obstetrics and
Gynecology, Thomas jefferson
University , Philadelphia, PA
Patrick Mahar Medicine/
Pediatrics, S Y/Buffalo Graduate
Medical-Dental Education
Consortium, Buffalo, Y
Thomas Malinich Medicine/
Pediatrics , outhern Illinois
University , chool of Medicine,
Springfield, IL
Michelle Mang family Practice,
Highland Hospital , Rochester, NY
Jeffrey Marchant Internal
Medicine, Medical College of
Virginia , Richmond, VA
Michael Markham Family
Practice, SUNY/Buffalo Graduate
Medical-Dental Education
Consortium, Buffalo , Y
Amy McGarry Pediatrics,
Georgetown Unive rsity Hospital ,
Washington , DC
Thomas McTernan Internal
Medicine, SU Y/Buffalo Graduate
Medical-Dental Education
Consortium, Buffalo, Y
Sumit Mehta Transitional ,
Chestnut Hill Hospital, Philadelphia , PA; Diagnostic Radiology ,
Stonybrook Teaching Hospitals ,
Stonybrook , Y

Mark Oberlies Internal Medicine,
Loyola University Medical Center,
Maywood , IL

moving into your

Joseph Rebhan Family Practice,
Wausau Family Practice,
Wausau, WI

George T. Moynihan Otolaryngology , Loyola University Medical
Center, Maywood , IL

Lori Kwan Internal Medicine,
Yale- ew Haven Hospital , New
Haven , CT

graduates who ore

community."

John R. Wright, MD
INTERIM DEAN

Jeffrey Richman lntenwl Medicine
(Prelim. ), Mercy Medical Center,
Baltimore, MD; Anesthesiology ,
Johns Hopkins Hospital ,
Baltimore , MD

Joseph Sheehan Pediatrics,
University of North Carolina
Hospital , Chapel Hill, C
A. MacDuff Sheehy lntemal
Medicine, Einstein/Montefiore
Hospital, Bronx, NY

Jenny Oh Internal Medicine,
LAC-USC Medical Center,
Los Angeles, CA

Marc N. Richman Surgery
(Prelim .), niversity of orth
Carolina Hospital , Chapel Hill,
C; Urology , University of North
Carolina, Chapel Hill , C

Nnenna Okereke Intemal
Medicine, Yale-New Haven
Hospital , ew Haven , CT

Jayson Roland Pediatrics, S Y/
Buffalo Graduate Medical-Dental
Education Consortium , Buffalo, Y

Dawn Simon Pediatrics, SU Y/
Buffalo Graduate Medical-Dental
Education Consortium, Buffalo,

Tamera Paczos Obstetrics and
Gynecology, Temple University
Hospital, Philadelphia, PA

Neha Sangwan Internal Medicine,
Temple University Hospital,
Philadelphia, PA

Prashant Parashurama Internal
Medicine (Prelim .) , Long Island
Jewish Medical Center, ew Hyde
Park , Y; Diagnostic Radiology,
The ew York Hospital , ew
York, Y

Jennifer Scarozza Medicine/
Pediatrics, SUNY/Buffalo Graduate
Medical-Dental Education
Consortium, Buffalo, NY

Anand Singh Surgery (Prelim .),
SUNY/Buffalo Graduate MedicalDental Education Consortium ,
Buffalo, Y

Kathleen Pastore Emergency
Medicine, Brigham and Women's
Hospital , Boston , MA

a

Andrew Stoeckl Surgery (Prelim .),
SU Y/Buffalo Graduate MedicalDental Education Consortium,
Buffalo,
; Orthopedics, SUNY/
Buffalo Graduate Medical-Dental
Education Consortium, Buffalo, NY

Joel Sebastien Surgery ,
Westchester County Medical
Center, Valhalla , Y

Joseph Stowell Transitional,
Shadyside Hospital, UPMC,
Pittsburgh, PA; Emergency Medicine,
Long Island Jewish Medical Center,
ew Hyde Park, l\lY

Carl Seon Orthopedics, Hamot
Medical Center, Erie , PA

Clayton Polowy Internal Medicine,
Rush-Presbyterian , St. Luke's
Hospital , Chicago, IL

f

Hans Stelmach Psychiatry,
niversity of North Carolina
Hospital , Chapel Hill , NC

Matthew Scozzaro lntenwl
Medicine, University of Florida
Program , Shands Hospital ,
Gainesville , FL

Christine Pluviose Family
Practice, Albany Medical Center
Hospital , Albany , NY

f

Sunil K. Srivastava lntenwl
Medi cine (Prelim .), St. Vincent's
Hospital, ew York , NY ;
Ophthalmology, Emory University ,
Atlanta , GA

Medical-Dental Education
Consortium, Buffalo, NY

Achini Perera Internal Medicine,
University Health Center,
Pittsburgh , PA

0

David Serra Obstetrics and
Gynecology, SUNY/Buffalo Graduate

Sophia Streete Family Practice,
Jamaica Hospital Medical Center,
Jamaica, Y

Medical-Dental Education
Consortium, Buffalo,

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J. William Sparks Transitional,
San Diego aval Hospital,
San Diego, CA

Christopher Schaeffer lntemal
Medicine, University of Rochester ,
Strong Memorial Hospital ,
Rochester, Y

Mary Scott Obstetrics and
Gynecology, SUNY/Buffalo Graduate

Nicole Pazzaglini Obstetrics and
Gynecology , Abington Memorial
Hospital , Abington , PA

u

Lily Snyder Family Practice,
Highland Hospital , Rochester,

Michael Scharf Psychiatry,
University of Rochester, Strong
Memorial Hospital , Rochester, Y

Viresh Patel Surgery (Prelim .),
nion Memorial Hospital ,
Baltimore, MD ; Orthopedics,
SU Y/Buffalo Graduate MedicalDental Education Consortium ,
Buffalo, Y

B

Anthony Shih lntemal Medicine,
Hospital of the University of
Pennsylvania, Philadelphia, PA

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Jeffrey Visco Surgery , SUNY/
Buffalo Graduate Medical-Dental
Education Consortium, Buffalo, NY

Gordon Wingard Emergency
Medicin e, Maricopa Medical
Center, Phoenix , AZ

Keith Volmar Patholog), johns
Hopkins Hospital, Baltimore, MD

Mei Y. Wong Surgery (Prelim .),
SU Y/Buffalo Graduate MedicalDental Education Consortium,
Buffalo, NY; Neurosurgery, SUNY/
Buffalo Graduate Medical-Dental
Education Consortium, Buffalo, NY

Andrew A. Wagner Urology ,
niversity of Massachusetts,
Worcester, MA

Jenny S. Oh, left, and Doris Vanderpool
share Match Day results.

Jennifer Walsh Intemal Medicine,
SUNY/Buffalo Graduate MedicalDental Education Consortium,
Buffalo, Y

Thomas Trevett Obstetrics and
Gynecology , University of
California at San Diego Medical
Center, San Diego , CA

Garin Tomaszewski Intenwl
Medicine (Prelim .), Loyola
University Medical Center,
Maywood , IL; Diagnostic
Radiolog) , University of Colorado,
School of Medicine, Denver, CO

Colleen Weber Obstetrics and
Gynecology, University of
Rochester, Strong Memorial
Hospital, Rochester , Y

Edna Valdes Surgery , New York
Hospital , Medical Center at
Queens, Queens, Y

Angela Weirich Family Practice,
Carilion Health System,
Roanoke , VA

Doris Vanderpool lntemal
Medicine, St. Mary's Medical
Center, San Francisco, CA

Hannah Toon Intemal Medicine
(Prelim ), Mt. Auburn Hospital ,
Cambridge, MA; Anestllesiolog),
Massachusetts General Hospital,
Boston , MA

Mark Weirich Family Practice,
Carilion Health System,
Roanoke , VA

Anthony Villani Pathology,
University Health Center,
Pittsburgh , PA

Linda Van Intemal Medicin e,
Stonybrook Teaching Hospitals ,
Stonybrook, Y
Daniel Yawman Pediatrics,
University of Rochester, Strong
Memorial Hospital, Rochester, 1Y
Li Zeng lntemal Medicin e
(Prelim .), Lankenau Hospital ,
Wynnewood , PA; Anesthesiolog) ,
Hospital of the University of
Pennsylvania, Philadelphia , PA
Michael Zionts Family Practice,
S NY/Buffalo Graduate Medi calDental Education Consortium ,
Buffalo, Y

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Commencement for the School of Medicine and Biomedical Sciences at the Stole
Unive~ of New York at Buffalo wos held on May 22,

1998, at the Center for the

Arts on the North Campus. On that day, the school graduated 138 new physicians
and 37 new PhD scientists.

Pictured clockwise from below: 1 Therese Caligiuri and one-year-old
Willy; 2 Moster's degree candidates; 3 Closs Speaker Sunil K. Srivastava;
4 Nnenno Okereke receiving diploma from UB President William R. Greiner, School
of Medicine's Interim Dean John R. Wright, MD, leh, and Vice President for Heohh
Affairs Michael Bernardino, MD, center; 5 Rochno Gupta, leh, and Nicole Kerner;
6 Students entering the auditorium; 7 Christopher P. Schaeffer.

I

�Physicians Reaching Out to Students
-NEW PHYSICIAN-STUDENT MENTORING PROGRAM

ED! CAL ~CHOOL IS THE TOGGHEST CHALLE'\GE

many students

have ever faced. The pressure to achieve is intense; the work,
grueling. When a problem arises, where do they turn? How
do they cope? The University at Buffalo School of
Medicine and Biomedical Sciences is offering help in
the form of a new Physician-Student Mentoring
Program that links first-year students with physician
mentors in the community
"Medical school is a parochial system, and students can feel so lost in
it," says jack Coyne, MD, past president of the UB's Medical Alumni Association, who helped spearhead the
program. "You lose contact with the
world around you. During the first
two years you don't even have time to
read the newspaper. When yo u' re

they're struggling in a
class and don't know
where to find help. Maybe they're
homesick and could use an empathetic
conversation over a hot meal. Perhaps
their troubles run deeper.
"When I was a student, a number of
my classmates had concerns and problems and they didn't know where to go
with them ," recalls Coyne, who graduated from UB's school of medicine in

"STUDENTS WHO EXPERIENCE STRESSFUL SITUATIONS, WHETHER
THEY RESULT FROM REAL-LIFE TRAGEDIES OR THE EVERYDAY CHALLENGES OF LIFE AND MEDICAL SCHOOL, NEED TO FEEL THAT THEY
HAVE SOMEONE TO TALK TO, SOMEONE WHO IS INTERESTED IN THEM
AND WILL TRY TO HELP."
- 1N T E R I M

being pushed to the limit in that setting, you can easily feel overwhelmed."
In the program, which was begun
last fall , the mentoring physicians act
as confidantes, friends and sounding
boards for students, who can call on
them under any circumstances. Maybe

®

0 EA N

J 0 HN R.W

RIGHT

1985 and today is medical director of
child advocacy centers for Erie and
iagara counties and for pediatrics at
Mercy Hospital. "It can be difficult for
a student to share things with people
in the administration. With this program, students have an opportunity to

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meet physicians who can help them or
who know people who can help them
without having to go 'on the record."'
As a student Coyne watched classmates grapple with depression and
drug problems. One, overwhelmed by
his struggle and unable to talk about
his despair, committed suicide, he says.
Mentoring may be a way to help, by
providing students with a safe haven
whenever they need it. "In that case
we're talking about a very
serious situation , but
more often it will be the
case of a student who's
feeling stress during
final exams or who
maybe wants a physician
to open up his office so
he can see the clinical side of things,"
says Coyne.
The new mentoring program is informally structured. At the beginning
of the 1997-98 school year, physicians
who volunteered to participate received
a letter with the name and telephone
number of the student with whom they
had been matched. Student participants
received the physician's name and home
and office telephone numbers. Physicians have been encouraged to initiate
contact to overcome any hesitations
first-year students may have due to
shyness, intimidation or worry that they
will be a bother.
When the program was announced
at the beginning of the year, 107 of the
medical school's 135 members of the
class of 2001 signed up. A survey conducted in early 1998 revealed that of
the participants, 29 had been in contact with their mentors, and of that
number, 22 described the relationship
as helpful. In the survey responses ,
the program was described by students as "sup portive," "reassuring,"
"informative" and "friendly, " with several adding that they received "good
pointers" from their mentors.

an

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Such feedback, says medical school
interim dean john R. Wright, MD, indicates that the men to ring program is reaching out to students in need, which is its
goal. Wright recalls past situations where
he has helped students get through difficult times. One particularly difficult case
that stands out in his mind was that of a
distraught first-year student whose sibling had been murdered.
"There is a real need for this kind
of program," Wright emphasizes. "But
in the past, attempts to provide such
assistance had been somewhat haphazard , so we thought it would be
beneficial to the students to have a
more organized effort in place.
Students who experience stressful
situations , whether they result from
real-life tragedies or the everyday
challenges of life and medical school,
need to feel that they have someone
to talk to, someone who is interested
in them and will try to help. "
The idea for the new PhysicianStudent Mentoring Program was
brainstormed at an alumni executive
committee meeting last year. Once the
program was established and an-

nounced , area physicians were quick
to respond to the call for volunteers ,
with 75 immediately signing up and a
few dozen more coming on board since
that time.
"Advisement is something that all
medical schools struggle with, " Wright
says. "Often it's not done particularly
successfully. It requires a certain degree of organization because you want
to make sure students know these services are available , yet you don't want
to meddle in people's lives, and you
don't want to be intrusive. From a different perspective, however, it's a good
way for medical students to see how a
doctor actually practices medicine."
But the student isn't the only one
who benefits from the rapport. It also
allows physicians to reconnect with
their past, Coyne says , and to take a
look into the future of medicine. "I
get a sense of belonging. We as physicians lose touch with what the
students are going through. It helps
us stay in touch with the system and ,
more importantly, with the problems
students are having as they go through
the system ."

•
PHYSICIANS NEEDED

The Physician-Student Menloring
Program has met with an overwhelmingly positive response from students;
however, more physicians are needed.
To volunteer, please call the UB Medical
Alumni Association Office at 829-2778.

Earlier in the year , Coyne received
a call from one of the two students he
mentors. Her grandmother died , and
she just needed someone to talk to .
When he received the call , Coyne
realized how useful-and necessarythe program was . Then she told him
about a friend of hers who was interested in a mentor. ow he's a mentor
to three students . +

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Physician

Summer

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EDWARD H . WAGNER ,

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MD '65 , STOCKTON K I MBALL LECTURER

The patient

wAs A wiDow,

ss

YEARs oLD .

D ESPITE A HALF CENTURY OF CIGARETTE SMOKING,
SHE WAS DOING QUITE WELL .
Then, from the tiniest hint of trouble,
began a slippery slope of debilities. Her
legs had been feeling weak; a lifelong
walker, she was moving more slowly. Her
family physician could detect no pulse in
her feet and diagnosed intermittent
claudication. Then a series of upperrespiratory infections buffeted her lungs
and she began to develop wheezing. The
physician searched for a carotid pulse and
found none; he prescribed aspirin. He
referred her to a vascular surgeon, who
examined her and concluded she was not
a candidate for surgery. She was at very
high risk for stroke, he said, and would
benefit from taking it easy.
She did, and got weaker. She entered a
skilled nursing facility for a while. And

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when she went home, it was, for the first
time, with a cane.
Now this previously vital womanwho used to take long walks, do her own
shopping and maintain an active social
life-is largely confined to walking to the
bus stop and back.
"This is not an uncommon story,'' says
Edward H. Wagner, MD '65, MPH, who
delivered the Stockton Kimball Memorial
Lecture at the University at Buffalo School
of Medicine and Biomedical Science's 6lst
annual Spring Clinical Day, on April 25.
"And it illustrates the difficulties she is
faced with in trying to deal not only with
these illnesses, but with their impact on her
ability to function."
The good news, he went on to say, is that

Physician

Summer

1

9

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�this impact can be managed and mitigatedif the physician intervenes, and if, in the long
run, we design a health-care system that goes
beyond acute care and supports older people's
efforts to take control of their own health.

can they communicate and collaborate with
their medical providers-often a bevy of specialists in addition to their primary physician-to devise a treatment plan.

A STRUGGLE ON BOTH SIDES

Wagner says the health-care system, as currently configured, is oriented toward acute
care, addressing the presenting complaint
without necessarily delving into the underlying health factors in the patienfs life. "But
when illness plays itself out over years or
decades, the patient's needs change, and a
reactive system may not
be as relevant as it was in
ASTHEAVERAGEAGEOF
the past,·· he says.
Using the 85-year-old
AMERICANS CONTINUES TO CLIMB,
widow to illustrate the
point, he adds: "She
THERE WILL BE MORE DEMAND FOR
wanted to walk, to play
PHYSICIANS WHO CAN DEAL
bridge, to go downtown
shopping. The system
EFFECTIVELY WITH THE ISSUES OF
wanted to know what her
presenting complaint was
OLDER PATIENTS.
that day. This was a clear
mismatch between what
was important to her and what was important
to her health-care provider."
The current medical system, he says, focuses on the short term. It pays little attention
to delegating health-promoting tasks to the
patient, to issuing reminders over months or
years that would promote good health and to
helping patients educate themselves about their
condition. "The older patient," Wagner says,
"needs a different system: one that takes a
prospective view and looks down the road to
next month, next year, a few years from now."

A SYSTEM BUILT BACKWARDS

Wagner, who spoke to a large luncheon
audience at the Buffalo Marriott, has made a
career of thinking about the public policy
aspects of medicine. A general internist and
epidemiologist, he directs the Center for Health
Studies and the MacColl Institute for Healthcare Innovation at the Group Health Cooperative of Puget Sound in Seattle, Washington.
He also teaches at the University of Washington School of Public Health and Community
Medicine, where he is a professor of health
services. His research interests include the care
of geriatric patients.
As part of a Spring Clinical Day focused on
'"The Aging American," Wagner pain ted a broad
picture of how practitioners tend to treat their
older patients-and where they fall short.
"The older patient is a struggle for physicians,'· he notes, "but it's also a struggle for
the patient to deal with the physician. The
patient needs to be an effective, educated
manager of his or her own health. So the
question becomes, what kind of health-care
system do we need to support this?"
Wagner says patients themselves must
address several issues: what activities can
they pursue that would promote good health;
what skills can they learn to monitor their
illnesses and adapt to changes in their bodies; how can they manage the effects of those
illnesses on their ability to function; how can
they manage the emotional impact, such as
their ability to be a "social animal"; and how

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CONTINUED

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�''

THE OLDER PATIENT NEEDS A DIFFERE T SYSTEM: ONE THAT ... LOOKS
DO\VNTHEROADTONEXTMONTH,NEXTYEAR,AFEWYEARSFROM TOW.

C O N T I NUED

FROM

PAGE

23

It's not that individual physicians don't recognize these needs and try to meet them, Wagner
adds. "But providers are working in a system
that doesn't help them do this."
The older patient's priorities, he says, generally are twofold: preventing disability and falls,
as well as "the potentially devastating impact of
the fear of falling"; and managing the chronic
illnesses that most older people have. From 75
to 80 percent of older people have at least one
chronic illness, he says, and about half struggle
with two or more.
Do NOT Go GENTLY

The encouraging news,Wagner says, is
something that has become a fundamental tenet of
geriatric medicine:
THE PATIENT NEEDS
"The deleterious
effects of aging may
TO BE AN EFFECnot be inevitable."
He displayed a
TIVE, EDUCATED
chart that seemed to
prove a piece of common
wisdom: Be it
MANAGER OF HIS OR
pulmonary function
or muscle strength,
HER OWN HEALTH.
oxygen-uptake capacity or endurance,
a human being's physiological capacity declines with age. But, Wagner says, that truism
applies to the population as a whole; it's a
mistake to assume that each individual will
follow that path. The challenge for each individual patient is to buck the trend and resist
the declines of age-a concept known as
"successful aging."
''We're now beginning to understand the
factors that lead to successful aging," Wagner
says. "Physical activity is probably the most
important. Individuals who become sedentary
probably will have an increased decline." He
points to the concept of"deconditioning" -the
idea that with disuse, any physiological system
will weaken. "This," he says, "is an enormously
powerful tool for understanding decline."
SOME PRACTICAL APPROACHES

So how can physicians work with their elderly patients to maintain a good quality of life

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despite the chronic conditions that often come
\Vith advancing years? Wagner again suggests
that we focus on patients' functional abilities
and their ability to manage their own health
care. For example, to avoid often-debilitating
falls, patients might be encouraged to practice tai chi, or pursue endurance and strength
training. To reduce incontinence, they can do
Kegel exercises or consider pharmaceutical
remedies. And to help patients in managing
their own care, he says, the key concept is
empowerment. "Handing them a book is not
useful,"' Wagner says. '·Providing them with
organized problem-solving help is"-such as
suggesting sources of information, connecting a patient with support organizations, and,
in general, treating the patient as an equal
partner in health-care decisions that affect his
or her life.
For the physician trying to better organize
his practice, Wagner suggests thinking about
how we accomplish six tasks or roles:
+ Responding effectively to the acute problem.
+ Making sure the patient's overall status is
assessed accurately.
+ Providing first-class self-management
and support.
+ Finding ways to communicate and
coordinate among the primary physician
and specialists.
+ Advocating for patients in the community
so that they receive the care they need.
+ Using data systems and technologies, such
as registries and reminder systems, so longterm patient care doesn't depend entirely on
the memory of the physician.
Physicians don't necessarily have to accomplish all these tasks, Wagner says. They
can be delegated to people on their staff or
elsewhere who are trained for those roles.
As the average age of Americans continues
to climb, there will be more demand for
physicians who can deal effectively with the
issues of older patients.
Fortunately, Wagner says, the science of
treating older people is starting to come together. "I think this is an exciting time. For
the first time we're moving beyond philosophy to evidence," he says. "There's clear
evidence out there that we can improve outcomes, and I look forward to working with
you on this in the future." +

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--¥"

•Sprin~gaClinrcall•Dao/•Gatherimgs........._

Lehto right: Jared C. Barlow, outgoing president of
Medical Alumni Association; Bertram A. Portin, assistant
dean for Alumni Affairs; and Elizabeth L. Maher, president
of Medical Alumni Association .

Class of 1973 at Stockton Kimball Lecture.

Lehto right:John J. Bodkin and Jared C. Barlow
with Edward H. Wagner, Stockton Kimball lecturer.

.110

Class of 1948 (pictured) shared the attendance trophy with Class of 1953.

Fifty-year reunion doss at Saturday's luncheon.

John R. Wright at Saturday's luncheon activities.

Class of 1988 at Friday evening reception.

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�Medical Alumni Achievement Awards
~FE r!VIE ME Die \l Atl 1 1

Ac HIE\ E \H·

I A"

on"

were presented

to the following four University at Buffalo alumni at Spring Clinical Day,
April 25, 1998, at the Buffalo Marriott Hotel.
RONALD BATT

MD

CLASS OF 1 958

-Introduced by
Dr. Richard Romanowslli

"Throughout his career, Dr. Batt has been
an innovator in obstetrics and gynecology
and an outstanding teacher and superb
clinician with special expertise in
endometriosis and microsurgery,"
Romanowski said. "He has been a pioneer
in encouraging the use of laparoscopy in
his field and, along with his colleague
Dr. aples, has been recognized for his
research in infertility and for his efforts to
find more conservative measures of treating pelvic endometriosis."
A prolific writer and medical historian, Batt has published some 20 peerreviewed articles and more than 25 book
chapters and monographs. He was a coauthor of Another Era: A Pictotial History
of the School of Medicine and Biomedical
Sciences, State University of Ne~~ Yorh at
Buffalo, published in 1996. In addition,

he has also produced a number of audiovisual programs used in teaching. "I see
residents and students helped by his work
with these programs," Romanowski
noted, "and that's very gratifying.'' In
recognition of his contribution as a
teacher, Batt received the 1995 Chief
Residents Teaching Award, which is inscribed: Some men lift the age they inhabit
until other men walll on higher ground
during that lifetime.

A leader in his community, Batt has
organized many medical missions overseas to places such as the Ukraine in an
effort to help his colleagues in less
advantaged countries update their skills.
"So for these contributions-for his
ongoing patient care, his teaching and his

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research, I thank him on behalf of us all for
the work he's done throughout his career,
day by day," Romanowski concluded.
RONALD "SKIP" GARVEY. MD

CLASS OF 1953

-Introduced b) Dr.]. Bradley Aust

Ronald "Skip" Garvey is an accomplished
surgeon, professor and health-care
administrator, Aust said. A native of
Olean, Garvey was a scholar athlete who
attended Harvard College, where he
played football. After medical school,
Garvey completed his internship and
residency at Parkland Memorial Hospital
in Dallas, Texas, and a fellowship at the
IH. From 1961 to 1983, he was in
private practice as a surgeon, and for
nine of those years was also team physician for the Dallas Cowboys.
"In 1983, he went to Southwestern
Medical School as a professor of surgery," Aust said. "Going from practice
into an academic medical center is really
quite a change and he felt academic medical centers were ill-prepared to deal with
the problems that they faced, so he took
time out to earn an MBA in Hospital
Administration in 1986. At that time, the
university was about to build a hospital
at Southwestern and they looked around
for someone to spearhead the effort and
they picked Skip, so he shepherded
through the building of the [Zale Lipshy l
University Hospital and became its first
president and CEO, from 1987 to 1991."
Gan•ey then returned to teaching
until last year, when the university asked
him to accept a position as director and
chief administrative officer for its Health
Center in Tyler, Texas.
"Scholar-athlete, practicing physician,

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�dedicated family man, academic surgeon
and administrator-Skip Garvey is truly
a 'man for all seasons'," Aust said.
MILFORD MALONEY . MD
CLASS OF 1 953

-Introduced by Dr. Michael Sullivan
"I am honored to be able to present this
award to my classmate, Milford, who
has led an active career in academic
medicine as a teacher, researcher and
administrator, while simultaneously
maintaining a busy private practice,"
said Sullivan.
After a rotating internship, Maloney
completed residencies in both internal
medicine and cardiology. Following two
years in the U.S. Army Medical Corps.,
and another two years as a part-time
senior cancer research physician at
Roswell Park Cancer Institute, he entered into private practice in 1964. In
1968, he was named president of the
Western ew York Society of Internal
Medicine, and in 1969, became president of the Heart Association of Western New York. Also in 1969, he was
appointed chair of the Department of
Medicine at Buffalo Mercy Hospital, a
position he held until1994. During these
years-from 1972 to 1989-he also directed the American Board of Internal
Medicine's Medical Residency Training
Program affiliated with UB. In 1976, he
was named to the Steering Committee
for the ational Association of Program

Directors in Internal Medicine and a
year later, was appointed to the Council
of the National Association of Program
Directors in Internal Medicine. In 1974,
he was named president of the ew
York State Society of Internal Medicine
and in 1981, served as president of the
Medical Society of Erie County. Also in
1981 , he was appointed clinical professor of medicine at UB, after having served
as associate clinical professor since 1972.
In 1990, Maloney was inaugurated as
president of the American Society of
Internal Medicine.
"I cannot imagine how he managed
to do all this in his career," Sullivan
noted, "but it's for accomplishments
such as these that we present this award."
KENNETH

R.

NISWANDER , MD

CLASS OF 1 948

-Introduced by his son
Philip N. Niswander, MD
"I am honored to introduce my father.
It's particularly easy to sing his praises as
a colleague because he has so many outstanding achievements, '' said Philip
iswander, who gave a brief overview of
his father's career. After completing a
rotating and a surgical internship and
residency training in obstetrics and gynecology, Niswander entered into private practice in Buffalo from 1953 to
1964, during which time he was an assistant clinical professor at UB. In 1964, he
was made an assistant professor; and in

1965, an associate professor. From 1963
to 1967, he worked as an obstetrician in
the Child Development Program at
Children's Hospital in Buffalo, and for
three years-from 1966 to 1969-he also
served as chief of Obstetrics and Gynecology at the hospitaL In 1969, he
accepted a position as professor of
Obstetrics and Gynecology at the University of California at Davis, where he
also served as chair of Obstetrics and
Gynecology from 1969-1982.
Speaking of his father's accomplishments, Niswander said, "During this time
he published over 150 articles, as well as
a textbook on obstetrics, which is currently in its fifth edition. otable among
his research accomplishments, in my
opinion, is his work showing that obstetric factors have little or nothing to do
with brain injury among infants or with
the development of cerebral palsy. This
research is noteworthy economically as
well as medically since it has contributed
to the limiting of medical malpractice
awards against obstetricians, who were
previously found at fault for misconduct
for any baby born malformed."
In concluding his remarks,
Niswander joked that, after consulting
with his brothers, it "was difficult to
find a single redeeming defect in our
father." On a more serious note, he
added, "Instead, as time passes, we notice that his reputation is enhanced and
that his abilities are sustained, and, for
this, we are very proud of him." +

New Alumni Association Officers Elected

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ltlil
CLASS

REUNIONS

First row: Darwin Moore, Norman Minde, \Villiam Bloom; second row:

Raphael Good, Harold Graff, Kenneth 1\Jiswander, Raymond Moffitt, orman
Paul, Lester Schiff; third row: Daniel G. Miller, Ansel Martin, Francis Peisel,
Vernon Lubs, Daniel Fahey, Michael Dzubaty; fourth row: Robert]. Hall,
Alfred Shapiro, S. Paul Zola, Myron Gordon, jasper Van Avery, Richard
Proplesch, \Varren Hollis, Glenn Doan.

First row: Thomas Geoghegan, Richard Nagel, David Batt, joseph Ruh,
Samuel Galeota,W. Ransom Kelley; second row: john Strachan, Donald

Ehrenreich, \-til ford \-Ialone\, jack Gold, Herbert Constantine, john
Handel, Molly Seidcnbcrg,Jacob Shammash, Thomas Comerford, Ronald
Garve}; third row: Marvin Wadler, Bertram Port in, Donald Rachow,
Michael Sullivan, Harold ·mulvan, Harle) Lindquist, Herbert Simpkins,
Howard Smith, James Orr, James Carlin, John Fenger.

First row: ~orton Spivack, Robert Perez, Michael Mazza, William Glazier,

jacques Lipson, Carl Contino, Richard Romanowski; second row: joseph
Bellanti, Bernice Comfort, john Float, Richard Rahner, Samuel Shatkin,
Gary Cohen; third row: jason Reder, Melvin Broth man, Eugene Friedberg,
Michael Genco, Alfred Stein, Franklyn Campagna, Richard Wasson,
joseph Zizzi, Robert Dickson, Richard Boyle, James Williams, Franklin
Zeplowitz, Thomas Cummiske), Marie Leyden Kunz, Harold Zimmerman,
jerr) Weisberg.

First row: john Schriver, \Villiam Heyden; second row: Stephen joyce,

E. Michael ulli\ an, David Malinov, Richard arins, Frank DeLaus,jason
Rudisill; third row: john Wadsworth, Thomas Reagan, Joseph Tutton,
Ernest Fatta, Robert Hamilton, Charles Tirone, Anthony Foti, George
Steiner.

First row: Leonard Argentine, Bruce ~toesser, Robert Rosen, Robert \filch,

Sara '&gt;trkm, Thomas Cumbo, Ronald Friedman second row: Ehas
Rosenblatt, Jonathan Rcynhout, Kenneth \1atasar. Jean Dwyer \\!I hams,
Lesbia Fcmande:: mith Le,in, Kenneth Eckhcrt, 1artial Knicser, Harold
Kulman, Rtchard Stamile, Barry Shult::.

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�CLASS

REUNIONS

First row: Thomas Dwyer, Charles Anderson, Kenneth Gayles,jeremy
Cole, Fredric Hirsh, Robert Lamantia; second row: James Marks,

Demetrius Ellis, Paul Kuritzky, Timothy ostrant, Sharon Kuritzky,
Reta Floyd, Lynda Sorrenti, Barry Sanders, john Przylucki, Daniel
Pietro, Frederick Beck, Michael Haberman; third row: Arthur Mruczek,
Patrick O'Connor, Da\·id Breen, Frederick Buchwald, Robert Fugitt,
Thomas Lombardo, Michael Sansone, john Klimas, Gary Palys, Daniel

First row: :-..1ark Kramer, Barry Rosenberg, :-\elson lsada, Alan Kosk•\\;
second row: Louise Barbieri, Clifton Pea), Ronald Somogyi, Cheryl

Aldrich, Rondie Emn jones, Linda :-.!orris, Elizabeth Doherty, Iris
Buchanan; third row: Paul \\'opperer, Richard Elman, tephen Gawronski,
Henry Wilamowski, Dand Sangster, Gregory Bennett, Simon Shaham,
Richard Busch,

~!atthe\\

O'Bnen, Angelo DelBalso, David

~!archetti.

First row: Catherine Goodfellow, Leslie Doolittle, Younghee Limb,

Patricia Flanagan, Suzanne Meyers-Tanbakuchi, Melinda Cameron,
Cynthia Pristach; second row: \ u-Fei Wu, Barbara Ostrov, Richard
Collins, Charles Niles, Allen Rosen, Neal Smith, Robert Stall, Gah;n
Anderson, Robert Rosen, Kenneth Murra), Andrea Man yon-Wild, Renata
Wajsman, Mark Schwager; third row: Francis Mezzadri, Peter Accetta,
James Wild, Kenneth Zimmerman,Jonathan Graff, Frederick McAdam.

First row: Ann Marie LeVine, Margaret Morey-Stager, Stephanie

Christensen, Mary Davill, Norah Lincoff, Andv Cappuccino, Lisa Benson,
Helen Cappuccino; second row: Sandra Everett, Constance Greene
Klocke, janet Flier Sundqmst, Dawn Hrab, Nicole Sasson; third row:
Richard Gilbert, Thomas Bellomo, Lori Luzi, Frank Luzi,Jeffrey Steinig,
Stephen Hughes, james Schlehr, Charles Everett, David Pochatko,John
Dusse, Kathleen O'Leary, Anthony Bartholomew, Mark Klocke, Kevin
Kopera, Brad Shumcl, john Barbaccia, janet Williams.

First row: Kevin Kelleher ,Jennifer ordby, Paul Fa\·orito, Honora Heffner

Favorito, Michael Aronica, Gill Farkash, Richard Hall; second row: Brian
Szymanski, jeffrey Senall, Michael Sweeney, Jeffrey Parnell.

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�Harry Bergman, '34,
Special Recognition
Award Recipient
has received
an Award of Special Recognition
from the Dean's Advisory Council of the University at Buffalo
School of Medicine and Biomedical Sciences for his life's work
in urology.
When he heard news of the award
in April, Bergman, 87, who lives in
Hollywood, Florida, said, "I never
expected anything like this. My work
has been out there for so many years,
this is beyond me."
The award recognizes that, in 194 7,
Bergman devised an instrument capable of obtaining an early neoplastic
degeneration inside an apparent benign tumor, an accomplishment for
which he received a national award
from the American Cancer Society in
1948. lt also acknowledges Bergman's
discovery of a radiological sign for
ARRY BERGMAN . ' 34,

cancer of the ureter, named "Bergman's
ign" in his honor by john Emmett,
professor of urology at the Mayo Clinic,
and first catalogued in Dorland's Medical Dictionary in 1981. Also noted in
the award is Bergman's work as a writer
and editor of many publications and
books, including his highly respected
text, The Ureter, which he published
in 1960 and revised in 1981.
Bergman graduated at the top of
his class at UB in 1934 at age 21,
making him the youngest graduate of
the school. He established a successful practice as a urologist and surgeon in Manhattan and the Bronx. ln
1978, he semi-retired in Florida,
where for the next decade he served
as a professor of urology at the University of Miami's Medical School and
clinical professor at jackson Memorial Hospital in Miami.
In presenting Bergman with the
award, the Dean's Council states its
resolve "to recognize him for his outstanding career contributions to medicine, especially for furthering the
knowledge of cancer of the ureter." +

Rob Bakshi, '91,Wins National
Neuroimaging Award
BAKSHI , MD . has been
awarded the prestigious Oldendorf
Award by the American Society of
euroimaging (AS ) . Bakshi was
cited for research he did in collaboration with his colleagues at
the Lucy Dent Imaging Center and
Millard Fillmore Hospital that involved
the use of brain positron emission tomography (PET) in the study of multiple sclerosis (MS).
The award, named in honor of Dr.
William H. Oldendorf, a pioneer in the
field of neuroimaging, is presented to a
young investigator for outstanding
neuroimaging research. Bakshi, a Buffalo native, graduated from UB in 1991
and completed postgraduate training at
Harvard and the University of California at Los Angles. He returned to Buffalo
in 1995 for a neuroimaging fellowhip
and subsequently joined the Dent eurologic Institute and UB's Department
of eurology.

OB

ONLY ONE INVESTMENT
LASTS A LIFETIME
• Exceptional college placement record
• Challenging curriculum with
14 Advanced Placement courses
• tate of the art visual and performing arts center
• More than 60 interscholastic sports teams
• Comprehensive communn:y sel'"\'tce proJects
• Average class si:e is IS
• Financial atd available
Admissions tests on these
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January 24, February 2
To resel"'e a place for testmg or for
addtttonal mfom1atton, please call:

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�Bakshi received the award on February 27, 1998, at the national AS convention, during which time he presented
a lecture detailing the findings of his
research work.
The effect ofMS on brain functioning
may play an important role in the
progression of the disease , but has
previously been poorly understood, he
reported. Using fluorodeox yglucose
(FDG ) as a tracer to measure brain metabolism by PET, widespread global and
specific regional hypometabolism was
noted in MS patients as compared to
healthy subjects. This effect of reduced
metabolism and consequently reduced
function was most profound in the frontal and occipital gray matter, and in the
white matter. These findings suggest
that FDG-PET may be a useful tool to
improve the understanding of the pathophysiology ofMS and track the response
of these patients to new therapies.
Other aspects of brain mapping
studying specific clinical MS protocols
have been completed and were presented by Bakshi
and his Dent
colleagues in
April 1998 at
the annual meeting of the American Academy of
eurology.
The work presented by Bakshi
Rob Bakshi, MD
in Orlando was
co-authored by RobertS. Miletich, MD ,
PhD ; Peter R. Kinkel , MD; Mari Emmet
and William R. Kinkel , MD , '54. The
PET research of the lucy Dent Imaging Center is being supported , in part,
by the Dent Family Foundation and is
performed in collaboration with UB's
Department of uclear Medicine. eurologists at the Dent Institute are also
using PET scanning to improve the
understanding of other neurologic diseases such as Alzheimer's disease , epilepsy and brain tumors. +

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Nedra J. Harrison, 'Tl,New
President Medical Society
EDRA J. HARRISON. 77. is the
new president of the Medical Society of the County of Erie. A
practicing general surgeon with
Delaware Surgical Group , P.C. , in
Buffalo , Y, Harrison was installed at the society's annual meeting
May 12, 1998. A native of Buffalo, she
earned her undergraduate degree at Rosary Hill College (now Daemen College)
in Amherst, Y. After earning her medical degree, she completed her internship
and residency training at Millard Fillmore
Hospital in Buffalo. She was in solo practice in general surgery for a number of
years following her postgraduate training
before joining her present group in 1994.

LASER

SYSTEM

CONTINUED

take out the tumor. I don't need an
expensive system to help me do that. '
This system is making it much easier and
simpler for a physician to find , biopsy or
excise a brain tumor," Landi says.
Another neurologic procedure DRTS
is greatly improving is the percutaneous
procedure for trigeminal neuralgia. Treatment of this condition involves placing a
needle up through the patient's face via a
hole in the bottom of the skull and either
burningorinjectingamedicationaround
the affected nerve. "What the DRTS system allows you to do is target a neural
foramen and place a needle directly into
it as opposed to how we do it now, which
is walking a needle along the base of the
skull until you pop through. This can be
very painful for the patients because they
need to be awake to tell you if you've hit
the right spot in the right part of the
nerve," landi explains.
In addition , the DRTS has also found
a broad application to spine procedures,
from guiding the placement of instrumentation to percutaneous procedures
for pain relief.

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Summer

Harrison, who is a
past president of
UB's
Medical
Alumni Association , is also a
voluntary clinical
assistant professor
in general surgery
at UB, where she
Nedra J. Harrison, MD
serves as a preceptor for senior medical students.
Harrison is a diplomate of the ational
Medical Board and the American Board of
Surgery and is a fellow of the American
College of Surgeons. Currently, she is a
delegate from Erie County to the House of
Delegates of the Medical Society of the
State of ew York. She is also a member
and past president of the Buffalo Surgical
Society, where she was the first woman to
serve as president. +

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Given the success of the DRTS to date ,
both Landi and lifeso would not be surprised if other, yet-to-be discovered, applications are found for the system
they invented. For each physician, it's
tremendously rewarding to see how use
of the DRTS is contributing to improvements in diagnosis , treatment, pain control and protection from radiation
exposure. 'There's no substitute for the
satisfaction you get from the people you
meet every day when you know you've
helped take away some of their pain or
contributed to their being treated in a
better way," Landi says.
lifeso, too, says he derives much satisfaction from seeing the benefits the
DRTS brings to his patients, a satisfaction compounded by the work he continues to do with young medical students. "I
still do a lot of work with students," he
says, "and I encourage them to explore
their ideas. If they have something they
want to talk about, I tell them to come on
in and we'll sketch it out." +
Ellt•n liolr/luntuli'OI//rillll!l'll/o this arlitlt•.

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Reducing Multiple Births
RELI\IINAR't RF'&gt;LARC II by a fertility
specialist at the University at
Buffalo School of Medicine and
Biomedical Sciences shows for
the first time that a hormone whose
role in fertility was thought to
be limited to triggering ovulation
may also support
growth of a developing egg follicle
during fertility
treatment.
The findings
suggest thatlutenizing hormone
(LH), a hormone present in the
second half of the menstrual cycle,
may perform the critical task of ustaining the growth of egg follicles
until ovulation, said Michael W.
Sullivan, MD, VB assistant professor
of gynecology and obstetrics and lead
researcher on the study.
They have important implications
for women undergoing fertility
treatments, Sullivan says, because
specialists formerly thought the only
way to keep a developing egg growing
was to administer follicle stimulating
hormone (FSH), which also causes
multiple eggs to mature.
By manipulating LH and FSH,
Sullivan says it could be possible to
sustain the growth and development of
one or two follicles in women undergoing fertility treatment while preventing
multiple ovulations, thus decreasing
the risk of multiple births. " obody
has looked at this before, because it
wasn't possible until the development
of the recombinant form of the two
hormones, which happened very recently," he says. "The finding is very
preliminary, but it is promising. "
The results are based on a prospective
trial involving 24 women that Sullivan

®

led while a fellow at the University of
Pittsburgh School of Medicine.
Successful infertility treatment depends
on the ability to manipulate precisely the
essential hormones involved, which requires their clear identification. Infertility specialists strive for a single birth;

however, a stumbling block to this end
has been identifying a way to limit the
number of eggs that mature during fertility treatment while keeping at least one
egg developing. During a normal menstrual cycle, FSH stimulates egg follicles
to develop. At a certain point in the cycle,
estrogen signals the pituitary to stop producing FSH, a signal that at least one egg
follicle is well and being nurtured. The
drop in FSH stops more follicles from
developing, all immature follicles die,
but the "recruited" follicle lives.
" obody knew why the follicle continued to thrive in the face of decreased FSH ," Sullivan says. "We
thought that FSH was required all the
way along, even at low levels. So stan-

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dard procedure during fertility treatment has been to continue FSH, which
keeps follicles growing, but also may
stimulate too many to develop.
"We've now shown that FSH is not
essential during the entire first half of
the cycle. We've discovered that LH can
make up for the deficiency ofFSH as the
follicle grows."
ullivan and colleagues stopped
production of fertility hormones
artificially in the
study group, and
then stimulated follicle development in
all the women with
recombinant human FSH. When a
14-mm follicle was
identified by ultrasound, the women
were randomized to one of four groups:
continued FSH treatment; FSH replaced with saline; FSH replaced with
high dose of recombinant LH, and FSH
replaced with low dose of recombinant
LH. After two days of treatment, researchers measured blood levels of estrogen, the sign that a follicle is healthy
and developing normally. Estrogen levels dropped in the saline group, indicating the maturing follicle had ceased to
thrive in the absence of FSH or LH. In all
three remaining groups, estrogen levels
continued to rise and pregnancies resulted in all three groups.
"This suggests that if you administer
FSH until one follicle matures, then
limit FSH and substitute LH, you can
support the growth of the maturing follicle, but won't recruit any more follicles," Sullivan says.
Also participating in the study were
A. Stewart-Akers, ]. S. Krasnow, S. L.
Berga and A.]. Zeleznik of the departments of Obstetrics, Gynecology and
Reproductive Sciences at the University of Pittsburgh School of Medicine.
Funding came from the IH and TAP
Pharmaceuticals. +

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Blood-Brain Barrier
Disruption and Hypoxia
HE LA TEST HIGH- TECH GEAR can't
protect climbers on Mount
Everest from one of the hazards
feared most by those who spend
time at extreme heightsoxygen deprivation , or hypoxia ,
resulting in the potentially lethal brain
swelling known as high-altitude cerebral edema.
Research conducted at the University at Buffalo School of Medicine and
Biomedical Sciences suggests that highaltitude cerebral edema is caused by a
disruption in the blood-brain barrier.
john A. Krasney, PhD , UB professor
of physiology and a specialist in
hypoxia, presented these findings on
April28 , 1998, at the 66th annual meeting of the American Association of eurological Surgeons in Philadelphia.
Krasney and colleagues in UB 's
Hermann Rahn laboratory of Environmental Physiology have developed
an animal model using sheep for studying hypoxia and cerebral edema in an
effort to learn more about how and
why these conditions develop and their
effect on cognitive function.
"Brain swelling, and also pulmonary edema, is one of the major problems at high altitude and we don' t
really know the cause of either,"
Krasney says. "It is not lack of oxygen , per se. At high altitude , the brain
has an adequate supply of oxygen,
because blood flow increases to compensate for the lower concentration
of oxygen in the air. Yet people still
get sick. "
In its mildest form, swelling of the
brain brings on the headaches and
nausea characteristic of acute mountain sickness. In its most severe form,

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unrelieved by retreat to lower elevations , brain swelling advances to highaltitude cerebral edema, which causes
disorientation, impaired mental function and death.
Information gained from the study
of high-altitude cerebral edema and
hypoxia is relevant to many people
other than those wealthy enough to
afford an Everest trek , Krasney notes.
"Thirteen million people go to Colorado every year to ski and 65 percent
develop at least a headache, " he says .
"Twenty-five percent
develop
acute mountain
sickness , and
l to 2 percent
develop highaltitude cerebral
edema. " Hypoxia
also is associated
with obstructive
lung diseases ,
sleep apnea and
other disorders.

Krasney's research using sheep has
shown that the symptoms of highaltitude cerebral edema are not caused
by an inadequate supply of oxygen or
glucose to the brain. Rather , it appears that an accumulation of malfunctions creates enough cerebral
blood pressure to force apart cells of

Physician

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the blood-brain barrier and allow fluids to accumulate in and around brain
tissues.
They theorize that acute hypoxia
may allow a decline in cyclic adenosine monophosphate (cAMP) , a chemical messenger involved in regulating
capillary permeability. The decrease
in cAMP may allow the cerebral capillaries to leak.
In addition , Krasney said, it is possible that , in the presence of hypoxia ,
another chemical messenger , cyclic
guanosine monophosphate (cGMP),
acts with nitric oxide , a vasodilator,
to promote and sustain permeability
of the blood-brain barrier. The combined influence of actions could
allow fluid to accumulate in the intracellular spaces, he says.
Yet another
mechanism
that may be at
work involves
eleva ted levels
of leukocytes
that may cling
to the lining of
cerebral blood
vessels
and
cause leaks in
the blood-brain
barrier.

Krasney and colleagues are attempting to clarify further the importance of
these mechanisms in the development
of acute mountain sickness and highaltitude cerebral edema. Their research
is supported by the ational Heart,
lung and Blood Institute. +
-LOIS

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HURWITZ &amp; RNE, P.C .
[

ATTOR

Link between Prostate Cancer
and Estrogen Studied

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SERVICI G
THE LEGAL
NEEDS OF THE
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CoMMU ITY

HE FIR&lt;, T 1 \ E~ TIC, -\TIO
of the been studied in men , especially in rerole of estrogen metabolism in lation to prostate-cancer risk," Muti
the development of prostate can- says. "Yet, men also produce estrogen,
cer will begin at the University at and we know that estrogen plays a role
Buffalo chool of Medicine and in the development of cancers in
Biomedical Sciences in October women. There is evidence also that
1998, funded by a $450,000 grant from androgens are increased in women who
the U.S. Army's Medical Research and develop brea t cancer later in life. "
Muti's goal is to determine if estroMaterial Command.
The 30-month study will determine gen metabolism is influenced by enviif differences in estrogen metabolism ronment and lifestyle in a way that
exist between healthy men and men increases prostate-cancer risk. The inwho develop prostate cancer. Infor- crease in prostate-cancer deaths among
mation on lifestyle habits also will be men who emigrate from countries with
low rates to the
collected to deterUnited States, where
mine if, as suspected,
rates are high , sugthese habits affect
"ESTROGEN METABOgests that environwhether estrogen
LISM HAS NEVER BEEN
mental factors play
breaks down into a
a
dominate role in
potent product that
STUDIED IN MEN,
the disease, she says.
may induce prostateESPECIALLY IN RELA"There is evice ll division , or a
TION TO PROSTATEdence that a sedenweak version that
tary lifestyle and
acts to discourage it.
CANCER RISK .. . YET ,
high-fat diet influThis never-beforeMEN ALSO PRODUCE
ence estrogen meexamined mechaESTROGEN , AND WE
tabolism to produce
nism represents a
a
potent estrogen ,
potential new avKNOW THAT ESTROGEN
while
an active lifeenue of s trategies to
PLAYS A ROLE IN. THE
style and low-fat diet
prevent this imporDEVELOPMENT OF
induce production
tant disease, said
of
a weak estrogen.
Paola Muti , MD, UB
CANCERS IN WOMEN ."
Potent estrogens
assistant professor of
may increase prossocia l and preventate cell division and
tive medicine and
lead investigator on the research.
increase cancer risk. It's possible that
Prostate cancer is the second lead- the influence of these lifestyle factors
ing cause of cancer deaths among men , on hormone metabolism, especially
and the American Cancer Society esti- estrogen metabolism, could be the link
mates that39,200 men will die of the between environment and prostatecancer risk." +
disease in 1998 in the U.S.
"Estrogen metabolism has never
L OIS
BAKER

B

EYS

• Managed Care
• Purchase &amp; Sale of Practices
• Business &amp; Tax Planning
• HCFA Safe Harbor Regulations

ysician

and Physician Self-Referrals
• Contracts with Private
&amp; Public Entities

• Employee Relations
Counseling
• Fringe Benefit Programs
• Representation Before
Government Agencies on
Audit &amp; Business Issues
• Facility Finance
and Construction
• Credentialing
and By-Laws
• Hospital/Medical Staff Issues

Please contact
Robert P. Fine or
Lawrence M. Ross
at 716-849 -8900

1300 Liberty Building
Buffalo.

ew York

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�· ···· · ··· ·· ·· ·· ··· · ·· · ·· · · · ·· ··· · · ·· ··· ·· · · ·· · ······· ····· · · ··· · · · · · ··· · ···· · · ···· · ·· ··· ·· m
·~!tl

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Taller, but Not Necessarily Happier
con- into changes in quality of life.
"If adult quality of life is what we're
tinues to presume that height is a
measure of personal satisfaction concerned with , then we should probin life, a new study by a team of ably be looking at factors in addition to
researchers at the University at height. Maybe we should take into acBuffalo refutes the idea that taller count experiences related to having a
is necessarily better. The study, which chronic medical problem in general,
compared the quality of life of adults and how this might affect adult adaptawho were treated for growth-hormone tion, " Sandberg says , stressing that the
deficiency as children with their healthy findings do not suggest that growthsame-sex siblings who experienced nor- hormone treatment has no benefit
mal growth, appears in a recent issue of for patients' quality of life as adults.
the journal of Clinical Endocrinology and
Metabolism (Vol. 83,
pp. 1134-1142.)
The researchers,
led by UB pediatric
psychologist David
Sandberg, PhD , a
specialist in the psychological aspects of growth-hormone
The study involved 140 former
deficiency, found that as adults , chil- patients- 117 males and 23
dren who were treated were as well- females- and 53 siblings, all over
adjusted as their physically healthy the age of 18. The mean age of the
brothers and sisters . They also were treatment group at the time of the study
doing much better as adults than previ- was 26. Information on several qualityous studies using non-sibling control of-life measures was collected by telegroups or norms from questionnaires phone interviews. The treatment and
follow-up study were conducted at
had indicated.
Results showed, unexpectedly, that Children's Hospital of Buffalo.
there was little or no relationship beBoth the data-gathering method and
tween the former patients' adult height the relatively large and complete study
or how much they grew over the course population give the findings special
of therapy and their reports of psycho- credence , Sandberg says. "Most studies
logical and social functioning. An im- use self-administered questionnaires ,
portant difference that did emerge was which are mailed to patients, giving
in marital rates: Siblings were twice as you limited control over the process.
likely to be married as former patients. Also , by using same-sex siblings, we
"This study questions whether there is account as much as possible for particia direct relationship between how tall pants' genetic and social backgrounds. "
The results showed no significant difyou are as an adult and how satisfied
you are with your daily life experi- ferences between the formerpatientsand
ences," Sandberg says. "Changes in their same-sex siblings in educational
height brought about by growth hor- attainment, gainful employment, the likemone do not automatically translate lihood they were living independently,
LTHOLGH POPCLAR CCLTLRE

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and social support or adjustment, which
involved aspects such as one's network
of friends and social activities.
There were slight differences between
the groups on a measure of general
health. Former patients reported more
health problems, and those missing other
hormones experienced more health and
social difficulties , a predictable outcome
in light of the fact that some patients still
have health problems, notes Sandberg,
who adds that he has no explanation for
the differences in marital rates.

The study places in perspective the
relationship between height and happiness . "We shouldn't get caught up in
the idea that making someone taller as
adults will necessarily improve their
quality of life," Sandberg says. "Our
goal is to allow each person to reach the
normal range so his or her short stature
doesn't constitute a physical disability.
Maybe beyond that we aren't going to
find benefits. Quality oflife is an enormously complex concept. "
Also participating in the study were
Margaret H. MacGillivray, Richard R.
Clopper, Caroline Fung, Linda LeRoux
and Dana E. Alliger , all of UB and
Children's Hospital of Buffalo . The
study was supported in part by grants
from Genentech . +
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"It has taken 30 years from the discovery of these animal models to finding
out the true cause of these anemias ,"
comments Michael Garrick. Recent
efforts to map the rat genome gave a
boost to the anemia research by providing enough markers to enable researchers
to begin mapping the Belgrade rat and
tists describe as a stunning example of conducting the D A analysis to find the
biological conservatism: The same gene that encoded the critical protein.
amino-acid change in the same gene in
"The publication in 1995 of the rat
the same protein is responsible for iron- genome inspired us to get together with
deficiency anemia in two different ani- the Harvard group to map the Belgrade
mal models. The details of iron metabo- rat, " says Garrick. Meanwhile, the Boslism-particularly the question of which ton Children's Hospital researchers were
proteins are responsible for iron attempting to map the microcytic mouse.
absorption in the intestine and for iron
What the two groups found was akin to
traffic within cells-have
lightning striking
long eluded researchers.
twice, he says. "We
The UB-Boston team has
were looking at two
. . . THE PROTEIN
concluded that it is
different models. We
ramp2that actually takes
APPEARS TO BE
didn't know we'd
up iron in the gastrointesfind the same thing.
INVOLVED IN NOT
tinal tract. Later, when
Not only is it the
iron is absorbed into cells
JUST ONE , BUT
same gene encoding
in the body, it must be
the same protein in
SEVERAL CRITICAL
delivered to the mitochonboth animals , but it
dria. "This protein also is
ROLES IN IRON
is the same aminothe major one involved in
acid change that
METABOLISM .
this critical, intercellular
distinguishes the
traffic step," says Garrick.
normal animal from
The current results, says
the mutant. "
Laura Garrick, as well as recent research
A group at Brigham and Women's
conducted elsewhere, suggest that the pro- Hospital in Boston independently found
tein also may be implicated in a third the same protein; however, they did not
type of iron transport, called nontransferrinhave a mutant animal that could help
bound iron transport, which comes into play identify its role. "They did find that
when there is excess iron in the body.
ramp2 also transports lead, manganese,
The findings of the UB and Boston cadmium, zinc, cobalt, nickel and copChildren's Hospital researchers build per. Thus the Belgrade rat could be defion decades of work at UB led by the late cient in some of these metals and thereRobin Bannerman, MD , and colleagues, fore may help us to understand human
includingjohn Edwards , MD, that re- variability in response to toxic material,"
sulted in the characterization of animal Garrick says.
models of two types of iron-deficiency
"However, this protein doesn't ananemia: the Belgrade rat and the micro- swer all the questions in iron transport, "
cytic mouse. Both animals are unable to he cautions. "What's remarkable,
absorb iron properly in the gastrointes- though , is that it shows up in so many
tinal tract or take it up sufficiently at the ways. It's a fantastic coincidence. " +
cellular level.
-ELLEN
GOLDBAUM

Major Step in Understandina Iron
Metabolism, Iron-Deficiency
cientists at the University at
Buffalo and Children's Hospital in
Boston (affiliated with Harvard
University) have identified and
characterized a protein that is the
single most critical known element
in iron metabolism.
The first protein to be identified as
essential for normal intestinal iron
absorption and the first mammalian iron
transporter to be characterized at the
molecular level, the protein appears to
be involved in not just one, but several
critical roles in iron metabolism.
The research, supported by the
ational Institutes of Health, was published in the February 5, 1998, issue of
the Proceedings of the ational Academy
of Sciences and highlighted in the
March 25 , 1998, issue ofjAMA.
'This finding allows us to take a major
step forward in our understanding of
iron metabolism," says Michael Garrick,
PhD, professor of pediatrics and biochemistry at UB and a coauthor of the
paper. Other UB coauthors are Laura M.
Garrick , PhD, clinical assistant professor
of biochemistry, and Michelle A.
Romano, research technician.
The discovery of the protein, called
ramp2, will allow researchers to increase their understanding of iron-deficiency anemia; it could also lead to
improved treatments for hemochromatosis and help manage exposure to toxic
metals. For example, the potential role
of ramp2 in hemochromatosis was a
main topic of discussion in a symposium titled "Molecular Medicine and
Hemochromatosis-At the Cro roads ,"
heldinBethe da , MD,May14-15 , 1998.
The work highlights what the scien-

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W ILLI AM MALONEY, '41 , wrties:

EDWARD A . TOR IELLO , '80 ,

Good to read about Ted Ross.
I'm glad some of the '41ers are
still alive. The war was rough on

been named to the board of directors of the American Academy of Orthopaedic Surgeons.

our class. I've retired from anes-

His election took place at the
65th annual meeting of the academyMarch 19-23,1998, in New

thesia and live in Maine, near
the shore. My health is fair. I do
a little fishing and go to the
Carribean most winters.

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has

Orleans. Toriello is chief of the
Department of Orthopaedic Surgery at Wyckoff Heights Medical Center in Brooklyn,

Y, and

GLENN

L. POST , '72 , writes:
"I am currently working and

attending orthopaedic surgeon
at St. John's Queens Hospital,

enjoying life in Kathmandu,

Catholic Medical Center,
Queens , Y. A member of the

Nepal, with my wife , May, a
Burmese
physician. I
am chief of
the health

E-maJU5

program at
the U.S. agency
for International
Development

You've done
all you can
for your
patient. ..
now what?

I

Classnotes tan also be
submitted by E-mail at:

ew York
State Orthopaedic
Society, he

currently
serves on
its board of di-

rectors. He is
also a delegate
of the House of
Delegates for
the Medical So-

here. Our program has an anbpnotes@pub.buffalo.edu.
nual budget of
17 million for
ciety of the
activities in maternal and child
health, HIV/AIDS, family plan- State of New York.
ning and infectious diseases.
ROSLY N ROMANOWSK I, '86 ,
epa! is a wonderful country
writes: ''I'm practicing hematolwith a rich and diverse culture,
ogy/oncology with Century
spectacular countryside and
Medical
Associates
in
friendly people. I was a Peace
Williamsville, NY. My husband,
Corps volunteer here from
Bob Campo, and I are enjoying
1977-1979 , during which time
our first child, Richard Joseph,
I completed a preventive mediborn January 1, 1998."
cine residency with a specialty
in international health at Johns
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s
Hopkins.

Suggest Hospice support and care. Explain how
Hospice also helps the whole family. Remind them
that you 'II be there with Hospice, still directing
care. Tell your patient that you and Hospice
together can help make the remaining time more
meaningful, more dignified and more comfortable.

JONATHAN

is
now at the University of Florida
M ICHAEL J .

p~~ 686.8077

5ALZLER ,'79 ,

at Gainesville, where he works
in research.

HOSPICE BUFFALO • HOME CARE BUFFALO • KRESGE RESIDENCE
LIFE TRANSITIONS CENTER • HOSPICE FOUNDATION

WE I NSTEIN ,

'93 ,

writes, "I am working in a
private pediatrics practice in
orthern Virginia, just outside
Washington, DC. I got married
in August 1997; my wife's name
is Sandra. I keep in touch with

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I

Edward Math '93 (he was my
best man). He will be doing a
one-year
fellowship
in

mary for 17 years and completed
his career with the ew York

thesiologists from 1984-1992.
He also served as a certification
examiner for the American Board

ROBERT J . EHRENREICH , '47 ,

died on April3, 1998, in a Philadelphia nursing home after suffering a stroke. Ehrenreich, who
fought a long battle with

State Health Department. Survivors include his wife of 56 years,
the former Marjorie Thomas.

of Anesthesiology for 25 years.

ThisJuly, I will begin my second
year of residency in dermatology at SUNY Stony Brook. Also,

died
March 19 while visiting relatives in Evanston, IL. Ament,

January 28, 1998, in Wanakah,
Y, at the age of 88. Saab, a surgeon, maintained a practice in

a pediatrician, allergist and clinical assistant professor in UB's

my wife, Kimberly, and I would
like to announce the birth of our

who was 79, was a clinical professor of anesthesiology and vice

Lackawanna, Y, for more than
50 years. He was also a taff phy-

School ofMedicine and Biomedical Sciences. In his 43-year prac-

first child, Danielle Leigh, on
May 23, 1998. She was one

chairman for educational affairs
for the anesthesiology resident
program at UB. During his long

sician at Our Lady ofVictory Hospital and Mercy Hospital in that

tice of medicine, he was on the
staffs of Children's, Millard

community. Survivors include his

Fillmore, Sisters, Kenmore Mercy

career as an anesthesiologist at
Buffalo General Hospital (BGH)

wife, the former Jane Daley.

and DeGraff Memorial hospitals.
Ehrenreich, known as "Dr. Bob,"

Charlouesville, VA, next year.
SCOTT FLUGMAN , '96.

writes:

month early (surprise!) , but baby
and mom are doing well.
MARTIN C. MAHONEY , "95,

has

received the fir t-place award in
the 1998 American Academy of
Family Physicians Resident

JOSEPH R . SAAB , '43,
RICHARD

AMENT ,

'42 ,

and Children's Hospital, Ament
introduced new anesthesia techniques and developed the anesthesia resident program at BGH.
The author of numerous pub-

Scholars Competition. The
award was given for his paper,

lications, Ament was an expert in

"Correlates of Anticipated Infant Feeding in an Urban , Indigent Family Practice Setting."

the development of academic
anesthesiology in the U.S. and, in
recent years, became involved

The AAFP respresents nearly
84,000 family physicians, fam-

with the Wood Library Museum
of the American Society of Anes-

ily practice residents and medical students nationwide.

thesiologists in Chicago. In 1986,
he received the Distinguished
Service Award, the most presti-

OBITUARIES

died
December l l , 1997, in his Buf-

gious award of the American Society of Ane the iologists, which
he had served as president in
1977. Ament also was honored
with the dean's award for outstanding service from the UB
medical school in 1986, and in

falo home after a lengthy illness.
He was 81. rban, an internist,

1996, he received the OutstandingAiumnu AwardfromtheUB

was a former track star at UB
who once ran again Jesse Owens.

Alumni Association.
A member of many medical

In addition to maintaining a private practice in his residence, he
was a member of the medical

organizations, Ament was president of the ew York Society of

CARMELO E . PATTI , '32 ,

died

December 7, 1997, in Hornell,
Y. He was 89.
STANLEY T . URBAN. '40 ,

staff of Millard Fillmore Hospital for more than 50 years. He
was also medical director of the
Erie County Home and lnfir-

Anesthesiologists in 1967, a governor of the American College
of Anesthesiologists from 197577, and treasurer of the World
Federation of Societies of Anes-

died on

Parkinson's disease, which forced
him to retire three years ago, was

VINCENT J . CAPRARO , '45 , died

continued the practice of house
calls long after many physicians
had abandoned them, and often

on February 2, 1998, in Lorain
Community Hospital, Lorain,
OH, after a lengthy illness.
Capraro, a retired professor and

he called his patients if he went
out for the night. An early advo-

associatechairofthe Department

cate of parent-effectivness train-

of Gynecology and Obstetrics at
UB, was an internationally known
specialist in adolescent gynecol-

ing, he taught parenting sessions
in his office.
After traveling to tournaments with his tennis-playing

ogy and corrective surgery. He
establi hed a private practice in

daughter, Amy, Ehrenreich be-

1950 and joined the staff of
Millard Fillmore Hospital in
1951, later serving as chair of the
hospital's Department of Obstetrics and Gynecology and director of the training program for
residents and medical students
at UB. He was also chief of the
Division of Adolescent and Pediatric Gynecology and Corrective

came a chair umpire with the
United States Tennis Association
and officiated at matches in many
locations, including Madison
quare Garden and Forest Hills.
During those years, he had several encounters with the former
tennis "bad boy," John McEnroe.
He is survived by his wife,
Miriam; his daughter,Amy Haller

Surgery at Millard Fillmore Hos-

of Penn Valley, PA; two sons,
Richard A. of Potomac, MD, and
David B. of Wynnewood, PA; a

pital and chief of the Division of
Adolescent and Pediatric Gynecology at Children's Hospital. In

brother, Harold M; a sister,
Annette Irwin ofPembroke Pines,

1971 , he received the B Senior
Medical tudents' Award for out-

FL; and four grandchildren.

standing teacher, and in 1990 a
lectureship was established in his
honor by the UB Medical School

JAMES G . ROB I LOTTO , '48 , died

November 25, 1997, at age 74,
in Orchard Park, NY. After com-

Alumni Association class of 1945.
He retired in 1976 and moved to

pleting his residency at the old

Avon Lake, OH, in 1988.

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E.]. Meyer Memorial Hospital in

1950, Robilotto established a
general practice in Williamsville,
NY, which he maintained until

1999 Class Reunion Preview
I

The following is o profile of John H. Remington, MD, Closs of 1939, which will be celebrating its 60th reunion next Moy.

1958. He was on staff of Sisters
Hospital and served his anesthesia residency at Veterans Hospital from 1958 to 1960, after

JOHN H . REMINGTON , MD

After completing his internship at St. Mary's Hospital in

president of the American College of Surgeons Upstate

which he was a member of St.
Joseph Hospital in Cheektowaga,
Y, from 1960-1970. He was on

Rochester, New York, John H. Remington entered gen-

New York Chapter and the American Society of Colon and

eral practice for two years with his father, the late Alvah

Rectal Surgeons, and was on honorary fellow of the

the staff at our Lady of Victory

C. Remington, University of Buffalo medical school1897,

Royal Society of Medicine of london and Royal Austra-

Hospital, Lackawanna, NY, from
1970 to 1974. From 1974, until

after which he spent a year in the Pathology Deportment

lian College of Surgeons. He served as on examiner for

at the University of Rochester, conducting research with

the American Boord of Colon and Rectal Surgery and was

Nobel Laureate George Hoyt Whipple. He was subse-

on American Medical Association program director for

quently granted a three-year fellowship in surgery at the

the Section on Colon and Rectal Surgery. In addition, he

Mayo Clinic, where for one year he was first surgical

was founder of the Rochester Surgical Society and presi-

his retirement in 1981 , he was a
physician for ew York State.
Survivors include his wife of 49
years, the former Helen Reyda.
EDWARD A . PENN , '51 ,

died in

assistant to Charles W. Mayo. While at Mayo,

dent of the Research Society of the

he developed and described two new surgi-

American Proctological Society. Remington

after a brief illness. After gradu-

cal procedures and designed on instrument

received two awards from the Rochester

ating from UB and completing
his training in Boston , Penn es-

for performing bowel resections. Following

Academy of Medicine and was elected to

the fellowship, he was assistant surgeon to

Sigma Xi, the notional honorary research

the staff of the clinic and went on to earn on

society. He was also a trustee of the

MS degree in surgery from the University of

Hochstein Music School and the Allendale

Minnesota in 194 7. He then returned to

School and was president of the Genesee

December 1997 at his home in
Yarmouthport, MA, at age 71 ,

tablished a pediatric practice in
Fall River, MA, and served that
community for more than 39
years. He moved to Yarmouthport in 1992 and retired from
medicine in 1994. Dr. Penn was
the former chief of pediatrics at
St. Anne's Hospital in Fall River
during the early 1970s and was
Emeritus Fellow of the American Academy of Pediatrics and
past president of the Massachusetts Chapter of the Academy of
Pediatrics. He was also an associate professor of Pediatrics at
Tufts University School of Medicine and a member of the Health
and Finance Committee for the
National Academy of Pediatrics.
Surviving are his wife , Eileen

+

(Simon)and three sons.

B

u

f

f

a

l

a

P

Volley Antique Automobile Society.

Rochester, where he practiced in his specialty of colon

Today, Remington, who retired in 1979, is enjoy-

and rectal surgery.
During the course of his career, Remington was a

ing studying history, reading biographies and travel-

clinical associate professor of surgery ott he University of

ing with his wife, the former Katherine Weber, RN, who

Rochester, choir of the Deportment of Surgery at St.

formerly was a surgical nurse at the Buffalo General

Mary's Hospital, attending surgeon at Highland Hospital

Hospital. There, she worked with the late Marshall

and consulting surgeon at Rochester General and Genesee

Clinton, Herbert Smith, Thew Wright, Elmer Milch,

Hospitals. He has been in all 50 states and in 38 foreign

Wallace Hamby and others. The Remingtons (who

countries, serving as a lecturer or visiting professor in 14

reside on Old Mill Rood, Rochester, NY 14618), hove

of those countries.

three children: John Alvah, PhD, University at Buffalo
'66, oflucson, AZ; William Frederick, MD, of Pittsford,

Remington has published 52 articles, including

NY; and Susan Ann, MA, of Ann Arbor, MI.

three chapters in surgical texts. He has served as

hysician

Summer

1

9

9

8

+

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BUFFALO PHYSICIAN
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�</text>
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                    <text>AN OPENING TO A
NEW PER

ECTIVE

�Dear Alumni and Friends,

BUFFALO PHYSICIAN

\'olumc "3"3. '\lumhcr 2
ASSOCIATE VICE
PRESIDENT FOR
UNIVERSITY SERVICES
Dr Carole Smith Petro
DIRECTOR OF
PUBLICATIONS
Kathryn A. s~1wncr
EDITOR

Stephanie -\. L'nger
ART DIRECTOR/DESIGNER

\Ian J Kegler
ASSISTANT DESIGNER
lynda Harmel
PRODUCTION MANAGER

\nn Raszmann Brown
STATE UNIVERSITY OF
NEW YORK AT BUFFALO
SCHOOL OF MEDICINE AND
BIOMEDICAL SCIENCES

Dr John R. Wright, /ntmm Dea11
EDITORIAL BOARD
Dr Bertram Portin, Chai1

Dr Martin Brecher
Dr. Harold Brody
Dr lmda J Corder
Dr. ,\Jan J Drinnan
Dr. Jamc~ Kanski
Dr. Barbara \1ajeroni

Dr Elt;:abeth Oltmted
Dr Charles Paganelli
Dr Stephen Spaulding
Dr Brad lev T frua.,
Christoph~r .-\dam ...
Dr 1-'rankhn Zeplownz
TEACHING HOSPITALS AND
LIAISONS

The Buffalo General Ho;pital
\hcharl H Slum
The Children\ Ho,pllal of Buffalo
[ne County Medical Center
MerC\ Health Svstem
\1tlla;·d rillmor~ Gates Hospital
t-1IIIard Fillmore Suburban Hosp11al
~Iagara !'alb \lcmorial \ledtcal Center
Ro~\vcll Park Cancer In~titutc
'&gt;tster- of Chanty Hospital
Dnmis .\fcCarth\
\'ctcran'-. Affa1rs v\·cstcrn :'\C\\ York

Healthcare System
©The State Lmn·r~nv of '\;cw York

at Buffalo

'

Buffalo Phnician is puhhshed
quarterly by the State LnivcrSity of
~ew York at Buffalo School of
Mcdicme and Biomedical Sciences

and the Office of Pubhcallons. It

one of the best of times for those
privileged to be part of the medical teaching profession. New students-be they
undergraduate medical students, basic science graduate students, or house
officers-serve to energize the faculty.
At the end of june, Incoming Residents' Week and a day-long training program
for chief residents marked the beginning of the 1998-99 Graduate Medical
Education curriculum. Associate Dean Roseanne Berger and her staff organized
each of these highly successful and well-received programs. As a practical topic for
those destined to be the next chief residents, the program theme was Tools for
Leadership. Incoming Residents' \Veek was designed to prepare incoming house
staff for the transition from medical student to house officer, and more direct (albeit carefully
supervised) responsibility for patient care. In addition to learning more about how the health-care
system functions and the various regulations under which it operates (including the infamous NYS
"405" variety), the resident's role as teacher was emphasized. Indeed, by the end of the week, each of
the incoming residents had been provided with some very basic, small-group teaching principles and
an opportunity to apply these skills in a simulated ward-like environment.
During a White Coat Ceremony, convened on the first day of their orientation week in mid-August.
incoming first-year medical students were welcomed officially into the medical profession (see article
on page 22 of this issue). Traditionally, our medical students have taken either the Hippocratic Oatlt.
the Charge ofMainwnides, or what is locally referred to as the Physician's Oath at the time of graduation.
It occurred to some of our faculty that this might be "a little late" in their evolution as physicians and
the suggestion was made to have a ceremony at the vel) beginning of their preparation for the
profession. Accordingly, Assistant Dean for Students Dr. Tom Flanagan organized the White Coat
Ceremony, the high point of which is reciting the Physician's Oath.
At this year's ceremony, introductory remarks described what being a member of the medical
profession entails, particularly the obligations that come with the privilege. The fact that some aspects
of medical ethics tend to evolve with time was underscored by reference to Jerome Kassirer's (a
distinguished UB grad) editorial in the August 6, 1998, issu~ of the New England]oumal of Medicine.
On the other hand, it was noted that some ethtcal pnnctples have not changed since the days of
Hippocrates, including those embodied in our own Physician's Oath. The students were reminded that
when faced with ethical decisions, one's own ingrained value system often becomes invaluable; i.e.,
"Sometimes one has to set aside principles and do what is 'right."'
Following an address by Dr. Margaret Paroski, members of the senior faculty then provided each
student with a white coat in what was very much a graduation-like hooding ceremony, foiiO\ved b)
group recitation of the Physician's Oath. Smce It may have been some time since any of you attended
a graduation ceremony, particularly atUB, yo.u may want to read the oath, which is printed on pages
22 and 23 along w~ a descripuon of Its ongms. Please let us know what you think!
f.\11 IILR.\I D'&gt; Tm Blc.l;-.;:--.1;-.;r. Of A NE\\ \L\DI\tK YLAR,

IS

sent, free of charge, to alumni, faculty,
srudents, residents and friends. The
staff reserves the right to edit all cop}
and submisswns accepted for
publication.

~~

hN

R. W"G"', MD

Interim Dean
Sclwol of Mcdicirtc and Biomedical Sciences

Dear Fellow Alumni,
THE 11 u~t:-&lt;l \\HO YOLL'HFER THEIR Tl\tF to serve on the Governing Board of the Medical Alumni
Association do so for a variet; of reasons. One of my main motivations is to improve the medical school
experience. )-along with many of my fellow classmates-was one who complained in the early 1980s
about a torn-up Main Street, outdated anatomy labs and lectures m a drab G-26 lecture hall with its
equally drab "student lounge" across the basement hallway. The present medical student lounge is a
far cry from that basement lounge of the past. I am proud to be a part of the Alumni Association's effort
to furnish the student lounge (see related article on page 28 of this issue).
In the last issue of the Buffalo Physician, I mentioned some recent problems with the Medical
Alumni Scholarship Fund. I am happy to announce that the scholarship has been awarded this year
and the recipient, chosen by the Admissions Office, is Mr. jesse Cone, a 1998 graduate of the University
at Buffalo. Since the Governing Board of the Medical Alumni Association is committed to the future
of this scholarship fund, it \\&lt;ill be the subject of an article in a future issue of the Buffalo Physician.
I am tremendously grateful and happy to report that more than 150 busy physicians in the Buffalo
community have volunteered to serve as mentors for the new Physician-Student Mcntoring Program.
The students were equally enthusiastic, and the program is off to a great start. From the profile of the
first-yearstudcnts in this issue (sec page 22), I am sure you will agree that despite all the recent changes
in medicine, its future IS looking good.

~
E LIZABETH

L.

MAHER, MD

President
Medical Alumni Association

�VOLUME

33 ,

NUMBER

2

AUTUMN

1998

4
1

NOV 1 3 1998

2

China Rotation
FOURTH-YEAR

STUDENTS TAKE A

NEW

8

vt

APaUrough an

4H

Unexplored Field

• •

EUGENE M.

FARBER,

The Strengths
of Children
LUTHER ROBINSON , MD,

LOOK AT ANCIENT
DERMATOLOGY PIONEER,

WORKS IN THE U.S. AND

RECEIVES UB ALUMNI AWARD

ABROAD TO TREAT AND

by S. A. Unger

PREVENT FETAL

HEALTH-CARE

PRACTICES IN BEI..JING

ALCOHOL SYDNROME

Medical School

by Jessica Ancker

BIOGEN ENDOWS

Research

NEUROLOGY CHAIR AT

u B-LAWRENCE

.JACOBS
BODY SHAPE AND

NAMED FIRST HOLDER
BREAST CANCER

by Lois Baker
THE ARTFUL DOCTOR -

CHARLES

V.

U 8

PROFESSOR PURSUES

40

AND LOW PREGNANCY

PAGANELLI,
PASSION FOR PAINTING

PHD,

SPERM ABNORMALITIES

RATES

RETIRES AFTER

by Lois Baker
YEARS OF SERVICE

TO UB

STUDENT LOUNGE A

Class Notes

SOCIAL HAVEN FOR
MORE CLASS REUNION
MEDICAL STUDENTS
PHOTOGRAPHS AND

by Mara McGinnis
MEMORIES

Student Perspective
SECOND-YEAR

STUDENT NEVA DALEY
INAUGURAL WHITE

COAT CEREMONY

FOR INCOMING

LEARNS ABOUT

THE REALITIES

OF CANCER CARE

MEDICAL STUDENTS

by Mara McGinnis

CO\ ER PHOTO B\ jA'&gt;E ELLERY 00PKIKS.

Case presentation of two-year-old bor
with hypothyroidism.

Preventing fetal
alcohol syndrome.
Story on page 14.

�US ' S

FAMILY

MEDICINE

•

ROTATION
CHINA

IN

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ach spring, fourth-year students at the University at Buffalo School of Medicine
and Biomedical Sciences have an opportunity to participate in UB's Cross Cultural
Medicine Program, which includes a three-week clinical rotation at various
..--....-• medical facilities in Beijing, China.
During their stay in China, students gain knowledge about
the structure and financing of the country's health-care
system, as well as about its medical education. They also learn
about the role of traditional healing practices such as massage,
herbs and acupuncture, and have an opportunity to hone their
physical-examination skills by taking part in hospital rounds,
case presentations and various meetings (see following article
by jane Dophins, Class of 1998).
The Cross Cultural Medicine Program, which is partially
underwritten by Millard Fillmore Hospital, was begun in 1990,
when a working relationship between the medical school and
Beijing's Capital Medical Hospital was first established. "The
goal of the program is for the
students to learn about another
health-care system and to consider health and illness from a
different cultural perspective,"
explains S. Ramalingam, MD,
director of Cross Cultural Medicine and International Health at
UB, and clinical assistant professor in the Department of Family
Medicine and associate residency
director.
Ramalingam is convinced that
the opportunity for American
medical students to collaborate
with their peers from another culture and health system fosters
an openness to different perspectives on health, education and
society. He also believes that by observing a different culture
and its medical treatment of patients, students can take an
important step in furthering their understanding of the nature
of disease. "I want students to understand that medicine is
more than just interpreting lab tests. With all of our modern
technology, I sometimes think we've forgotten the primary
focus of medicine- treating the patient. "
A unique aspect of the rotation in China is the exposure
students gain to Traditional Chinese Medicine
LEFT: PEDIATRIC PHYSICA L
(TCM) and the ways in
THERAPY SESSION AT A
which it is collaboratively
integrated with Western,
FAMILY MEDICINE HOSPITAL
allopathic
methods. AlIN BEIJING THAT PROVIDES
though this type of colINTEGRATED , HOLISTIC CARE .
laboration seldom exiStS
between American phy-

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sicians and alternative medicine practitioners, there are indications that the role of alternative medicine in Western
culture is being reconsidered, not only in the clinic, but in the
classrooms as welL
ationally, the Society of Teachers of Family Medicine
has established a Subcommittee on Integrative Medicine
charged with developing the first curricular guidelines for
the teaching of alternative medicine in U.S. medical schools.
(The phrase "integrative medicine" has begun to supplant
the phrase "alternative medicine" when describing such
studies.) Ramalingam is one of five individuals selected
from across the nation to sit on the subcommittee. He
reports that after two years'
work, the group has completed its recommendations
and has submitted the proposed guidelines to the society for consideration, after
which they will be presented
to the Association of American Medical Colleges.
Also, in 1992, the Office of
Alternative Medicine (OAM)
was established through a Congressional mandate under a
ational Institutes of Health
appropriations bill to scientifically study the results of TCM. In its first year, the OAM was
budgeted $2 million to analyze, interpret and acknowledge
what effective therapeutic regimes exist in various alternative
practices. By 1997, that figure had risen to $12 million. _" _
Despite governmental encouragement and attempts by such
educators as Ramalingam to explore the role of alternative
healing methods , the historic lack of scientific rigor-as
defined by double-blind studies-is responsible for many of
the reservations Western-trained clinicians hold about the
efficacy of alternative medicine. A significant benefit medical
students enjoy during UB's China rotation, therefore, is the
opportunity to observe for themselves the positive results of
alternative medicine in a culture where TCM and Western
medical practices seem to peacefully coexist.
Summarizing what he feels are the benefits of the program,
Ramalingam says, "The excitement of a different culture fills
students with curiosity and enthusiasm to be inquisitive as
well as open-minded- attributes that will serve them well
throughout their careers as physicians. "

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�BY JANE ELLERY DOPKINS

•

cnve
THE

OST VALU

BLE EXPERIENCE OF MY MEDICAL EDUCATION

ditor's note: In March 1998,]ane Dophins, afourth-yearstudent at the Universit) at Buffalo's
School of Medicine and Biomedical Sciences, participated in the Cross Cultural Medicine
Program and its famil_v medicine rotation in China. In the following article, Dophins-n lw is
cw rent!) a resident in obstetrics and gynecology at Univcrsil) Hospital in Cincinnati, Ohiogi\ es a fi 1 stlumd account of her unique opportunit) to stuch abroad through L B~'l program
The thickly polluted Beijing air was chilly at 6:30a.m. as
six of us from the University at Buffalo School of Medicine
and Biomedical Sciences assembled in the courtyard of
Capital University in Beijing to meet our tai chi instructor
for our first lesson. As a participant in UB's three-week
Family Medicine rotation in China, I had not expected daily
tai chi lessons to be part of the program. To be honest, I had
very little knowledge of China prior to participating in this
rotation, so I really didn't know what to expect.
What I soon realized was that! had been given a remarkable
opportunity not only to learn about medicine in China, but
also to witness, firsthand, some of the changes the country is
experiencing politically, technologically and economically.

Beijing,

a City of
Contrasts
Over the course of the rotation,
the students and teachers at Capital University of Medical Sciences
became wonderful friends to us,
and our conversations with them
gave us unique insights into Chinese life and culture. The medical
studen ts told us about political
changes occurring in China and
spoke with great excitement about
the local elections taking place
for the first time. Even though
many students we met said they
were eager for greater freedoms in
China, including greater economic
freedom , all but a few were planning to apply for Communist Party

0

membership in order to secure jobs in well-respected hospitals.
Without party membership, we were told, a young physician
was sure to be sent to a remote rural province after graduation.
Many of these young men and women also told us they are in
favor of the one-child law as an essential element for China's
future success.
The economic and technological transitions were apparent
in the construction of new apartment buildings to provide
better housing for the 11.2 million people who live in Beijing.
While shiny skyscrapers funded by rich companies based in
Hong Kong were sprouting up, Chinese street workers continued to dig sewer lines and build new roads using hand shovels
and pure manpower. We visited several new department stores
very much like those in the U.S., but only one of them accepted
MasterCard or Visa. BMWs shared
the crowded roads with oxen-drawn
carts and men riding large tricycles
laden with pineapples.
During our rotation, we
stayed in comfortable hotel-like
accommodations on the university grounds, but discovered that
young teachers at the university
live in small university-owned
apartments that have no running
water. Beijing is a city of technological contrasts.

Modem Tools

and Modest
Facilities
Changes in the economy and
advances in technology have influenced the practice of medicine
in Beijing. We visited many teachB

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�ing hospitals in Beijing offering the best tertiary care available
in the country. ew technology is a priority for the doctors,
but many of the buildings and their grounds are poorly
maintained; for example, one day we saw a patient on a
stretcher being rolled through rubble to get to a brand-new
MRl machine. Although some buildings were modern , most
appeared to be very old. ln one hospital, paint was peeling
from the walls in a room where we examined patients who
were recovering well from kidney transplants. Also, the
telephone systems were not elaborate in any of the hospitals
we visited. In one facility, we noted that when a surgeon
wanted to get results from the pathology lab, he or she would
simply walk over to the lab and talk with the staff. Communication, we learned, was often delayed.

Case Presentations

and Hands-On Learning

Attending physicians and residents who spoke near-perfect
English escorted us on tours through their wards, stopping
at the bedsides of their most interesting patients to give case

presentations and teach
physical examination. As
the weeks passed, we had
CLASS OF 1998, DURING
an increasing number of
ROTATION IN CHINA .
excellent hands-on experiences. For example,
LEFT: HERBAL
we heard the murmur
of a mild tetralogy of
PRESCRIPTIONS BEING
Fallot in a nine-yearPREPARED IN TRADITIONAL
old boy. We palpated
metastatic cancer in the
CHINESE PHARMACY.
nodes of a cheerful elderly man who had
learned laryngeal speech after his tracheotomy but who had
never been told he had cancer. We also saw the butterfly rash
on the face of a beautiful 12-year-old girl with Lupus,
observed a retinal detachment for the first time, and palpated large spleens.
lt was thrilling to have the opportunity to feel with my own
hands or hear with my own ears physical findings l had never
experienced before as a medical student. After the instruction
ABOVE: JANE DOPKINS .

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�L received in Beijing, l feel much more confident in my
examination of the heart and abdomen.
We also toured operating rooms where barefooted surgeons
routinely perform delicate eye and open-heart surgeries, or
relieve bowel obstructions. A world-famous cardiologist showed
us his state-of-the art cardiac care unit while lamenting the
incredibly high rate of untreated hypertension in China.
In talking with obs tetricians, we learned that the cesarean
section rate is much higher for boys than for girls, and that
infanticide of female babies is uncommon in Beijing.
After completing a case presentation and an examination
of a patient, we often gathered in a conference room to discuss
the case and exchange information. Sometimes the Chinese
doctors taught us about a case they were particularly proud of
managing; at other times, they asked us for our expertise.
Usually the learning was mutual, and we finished our days
with a sense that we had exchanged medical knowledge as
well as shared our unique cultural perspectives.

J

Learning about
Traditional Chinese Medicine
In the U.S., allopathic doctors know very little about herbal
medicine , and most herbal preparations are sold as food
supplements with
very little regulation
YANG GUANG DEMONSTRATES
or knowledge of their
HOW MOXIBUSTION SUCTION ,
use . In China, the use
of herbs in Traditional
CREATED WHEN FIRE UNDER
Chinese Medicine
THE GLASS BALL BURNS OFF
(TCM) dates back
many millennia.
OXYGEN , IS USED FOR
During our visit,
TREATMENT OF PAIN .
we had glimpses of
TCM being practiced
RIGHT: WILLIAM J . MEDWID ,
as adjunctive therapy
CLASS OF 1996 , PERFORMS
to allopathic treatments and were able
PERCUSSION EXAM .
to observe how herbal
prescriptions are used to counteract the side effects of immunosuppressants in transplant patients. At a well-run psychiatric hospital, we learned that TCM is used with great efficacy in
preventing the movement disorders produced by antipsychotic medication. Also, at the Children's Hospital we saw the
TCM pharmacist mix a treatment for the common cold.
One day was entirely devoted to visiting aT raditional Chinese
Medicine hospital where TCM is the first-line treatment and

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allopathic medicine is used to assist treatment. While we were
there, our hosts demonstrated acupuncture on a man with Bell's
palsy and on a child with an Erb's palsy.
Also, a Traditional Chinese Medicine doctor demonstrated his special method for palpation of the pulse and
examination of the tongue. He examined a woman with all
the signs and symptoms of hyperthyroidism , and demonstrated that after two weeks of herbal medicine her pulse had
fallen from 120 to 85. The patient told us she felt much less
anxious and her heart seemed less jumpy.
One of the most successful wards in the Traditional Chinese Medicine hospital is the vascular ward, where physicians
use salves and systemic medicine to heal diabetic foot ulcers
with incredible limb-sparing success. We were awed and
amazed by it all.

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Reflecting on Similarities

and Differences

ln the U.S. , we worry about the politics and controversy
surrounding managed-care reimbursement and Medicaid. To
our surprise, we found that similar medical coverage problems exist in China. For example, we were told that a person
employed by a large company typically has medical coverage,
but others pay out of pocket for their care.
The friendships l made with our Chinese hosts were one of
We also learned that medical care in the country prov- the most meaningful aspects of my experience in Beijing. The
inces is difficult to obtain and of very poor quality; often president of Capital University of Medical Sciences, Mr. Shu,
patients have advanced disease by the time they are re- hosted us at a welcome banquet and then at a farewell dinner.
ferred to the large hospitals in Beijing for treatment. The He was well spoken, entertaining and easy to talk to. We got to
philosophy of care for the terminally ill is quite different in know several of the medical students during evening parties
China . Few heroics are employed for a terminally ill they arranged for us. On one occasion, the UB physicians
patient, and special hospitals, perhaps a bit like Hospice, teamed up against the Chinese medical students in a basketball
provide assistance for the dying and their families.
game in the center of the university compound. Also , despite
At the end of each day spent in the hospitals, we were the unexpected novelty of our first lesson , we enjoyed getting
exhausted, both emotionally and physically. Most of the time to know our tai chi instructor during our daily lessons, and we
we were impressed with how well patients were cared for , but developed a true fondness for the man who drove our bus to
there were a few times when we felt patients were not being the hospitals.
treated appropriately. Although we were amazed with the
Dai, a 26-year-old science instructor and graduate student
modern intensive care units and the great strides being made at the university, served as our facilitator for all our hospital
in cardiology, the realities of an overpopulated country with trips and, quite naturally, became our friend. She was eager to
very limited resources often weighed heavily on our minds as learn about our life in the U .5. and was willing to tell us of her
we rode in our minibus through the crowded streets ofBeijing experiences growing up in China. As we became better
back to our luxurious hotel for dinner.
acquainted , she told us about her dream of coming to study
Over wonderful meals , we had the opportunity to discuss in the U.S. but also helped us understand why she was very
among ourselves the many things we had seen and done fond of her life in China.
Dai not only talked to us about her life, but shared it with
during the day. Because our group of six consisted of two
us,
as well. She showed us her apartment, took us to the open
students, one nurse and three physicians, we often had a great
deal to teach each other. We became good friends , shared the Chinese markets and introduced us to her friends. l was very
fun of exploring the city of Beijing and helped each other sad to say good-bye to her at the end of our three weeks, but
we are keeping in touch through letters.
through moments of homesickness.

New Sights,

Learning and Maturing

Our three weeks in Beijing were not spent entirely in hospitals.
Our itinerary included several days of structured excursions to
such places as the Great Wall and the Summer Palace, as well
as a few afternoons of free time for shopping or relaxing. We
saw the old-style Beijing Zoo on a Saturday morning, when it
was filled with children eager to see the pandas. We spent
several evenings getting to know the city of Beijing by hailing
a tiny taxi, pointing to where we wanted to go on a map , and
then praying the taxi driver would take us where we had asked.
As we drove through the city, we saw evidence of the fact that
nightclubs and bars are becoming more popular now that there
is a little more freedom in China. One evening, we visited
Tianamann Square, which was even more impressive by night
than during the day.

On one of the last days of our visit to China, l sat with two other
members of our group, Pam Warner and Carol Chen, in one of
the university-run restaurants , eating a delicious dumpling
soup that had been boiled over a coal fire. We reflected on all
that we had learned of Chinese culture, medicine and human
nature. lt had been an exhausting three weeks, with moments
of joy and excitement mixed at times with confusion and
questioning when we felt that our fundamental values had been
profoundly challenged by the way things are done in China
compared to the U.S.
Each of us learned different lessons and matured in different
ways. The three weeks I spent on this rotation in China were
thought provoking and mind broadening and were, without a
doubt, the most valuable experience of my medical education. +

in Different Ways

Sounds and Friends

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�............................................... .. .... . .. .. . .......... ............. . ... .................

EUGENE

M . FARBER ,

DERMATOLOGY

PIONEER , RECEIVES

UB ALUMNI AWARD

. . . . . .. .. . .. . . . . . . . . .
OR

EL

c,F F

M.

FARBI R,

medicine was more than a calling; it was a fait accompli.

By the time he entered medical school at the University at Buffalo in 1939, three of
his older brothers-Sidney, Seymour and jason-had preceded him in choosing medicine
as a profession and were embarking on careers that, collectively,
would make the Farber name one of
BY

5 .

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UNGER

the more well known in science in
the latter half of the 20th century. "I was preconditioned to choosing
medicine as a career. Because of my brothers, I was surrounded by
medical books at an early age, and I never thought of doing anything
else," says Farber, who returned to Buffalo this spring to be honored
at the VB Alumni Association's annual awards dinner.
.
........
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�In

1959.

when Stanford•s medical

school

a leader in research to promote
lthough he followed
of the etiology and
understanding
in his brothers' foottreatment
of
psoriasis.
steps, Farber was
moved to Palo Alto,
quick to discover his own path,
The Support of
choosing in 1946 to pursue what
a Close-Knit Family
was then an unexplored area of
Born the 11th of 14 children, six
medicine: diseases of the skin.
of
whom graduated from the UniThe research contributions he
at Buffalo, Farber says
versity
made over the next four
.. . was selected as the first
that
despite
the size of his famdecades-especially with regard
chair
of
lhe
school's
newly
ily, there was always time for
to psoriasis-gave significant
books
and learning-pursuits
impetus to the development of
formed Department of
that were cultivated by his pardermatology as a medical speDermatology. a position
ents, Simon and Matilda Farber.
cialty. As a professor and chair of
"My father came to Buffalo from
the Department of Dermatology
h e held until 1986.
when he was 17. The first
Austria
at Stanford University's School
job
he
took
was as a stevedore on
of Medicine from 1959 to 1986,
he further contributed to his field as an academic clinician a barge on the Erie Canal, and from that start he went on
to build a very successful insurance business," says Farber.
and teacher. Today, Farber is president and chief execuDespite the press of maintaining a growing business and
tive officer of the Psoriasis Research Institute (which he
cofounded in 1986) in Palo Alto, CA, and continues to be raising a large family, both parents spent every spare

Farber

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A Path through an Unexplored Field
........ . ........ . ........................................

moment they had reading, so a love of learning came
naturally to Farber and his siblings. "My mother was amazing. She had so much work to do all the time around the
house, but at night she never rested without her book, and
my father read whenever he could, too. Our house was full
of books-well over a thousand, I'm sure. There was no TV,
so on cold winter nights in Buffalo, there was great pleasure
in getting into bed and reading and talking about books,
which we would hand down and recommend to each other."
sa young teen, Farber was nurtured and
strongly influenced by his older brothers
d their love of medicine. With their help,
he was able to observe operations and tag along on
hospital rounds while they were interns. "They liked
what they were doing o much and were doing so well,
it just seemed natural for me to do it, too. I never
thought otherwise," he says.

Passing On the Knowledge, One to Another
In 1935, Farber departed for Oberlin College in Ohio,
where he earned an A.B. degree in premed studies, after
which he returned to Buffalo to enter UB's medical
. . . . . . . . . . . . . . . . . . . .. . . . . . . .

. . .

school. Several of his brothers had attended Harvard, but
Farber decided to return home. "UB was one of the best
medical schools in the country, even then, " he says,
adding that he has never regretted his decision, as there
were a number of professors at the school who not only
greatly influenced him as a medical student, but who
served as models he would strive to emulate over the
course of his career.
"Guy Youngburg [then professor and head of the
Department of Biological Chemistry] was very inspiring
because he gave more than didactic lectures," he recalls.
"He was innovative in his teaching and taught by posing
problems instead of presenting repetitious lectures from
one year to the next. He encouraged me to think of
research in relationship to disease. "
In his preclinical years, Farber says Oliver P. jones
was his very memorable professor of anatomy. "He was
a kick. He was an old shoe with the students, who, as a
group, were then as they are today-very insecure, very
tense and overtired. And 1939 was a desolate year to
enter medical school because it was such a stressful time
financially; but 0. P. jones had a way with the students
that eased some of their burden .

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�"Then there was Earnest Witebsky," he continues, the
Compassion
respect he had for his professor of immunology still and Commitment
evident in his voice. "He was a German-jewish refugee
While Professor Osborne may have strongly influenced
Farber to consider choosing dermatology as an area of
who spoke with a slight accent. He had piercing blue eyes
and a kindly way. He's renowned for isolating the Bstudy to focus on in his career, the final push came from
antigen found in human blood,
his older brother Sidney. Already
which made blood transfusions
a distinguished pathologist well
safer. It was a big lift for the
on his way toward making dishis
war effort. And what was so
coveries in cancer chemotherapy
unusual-especially today-was
that would result in the Dana
preclinical
that even though he was a proFarber Cancer Institute in Bosfessor and head of a whole imton being named in his honor,
years. Farber says
Sidney had words of advice and
munology program, he was in
encouragement for Eugene once
the lab walking around from stuhe had graduated from medical
dent to student three afternoons
school and was in training, casta week from l p.m. to 5 p.m. "
...................
ing about for a direction to take.
Another UB professor Farber
"Sidney said to me, 'Why don't
recalls as clearly as if it were
you go into dermatology-there's
yesterday is Abraham Aaron, his
so much to learn, so much to do;
professor of clinical medicine,
it's a field that hasn ' t been
who "was feared and respected.
was his very memorable
explored yet. All medical research
He asked tough questions at the
professor of anatomy.
has
largely been done on the
bedside, and one of his adages
••He was a kick. He was
heart, lungs and kidneys, but the
that l remember to this day was
an old shoe with the
skin has been mostly ignored.
'Use a peashooter instead of a
students. who. as a
There's an opportunity for somecannon with respect to drug
group. were then as
one with a scientific bent to make
therapy. ' In other words, start
a contribution."'
they are today-very
cautiously." With a chuckle,
With those words, Farber and
Farber adds, "I used that same
insecure. very tense and
his
wife of two years, Ruth Seiffert,
quotation with my students for
overtired.••
were
soon on their way to Minne35 years, and l imagine some of
sota. "I was an assistant resident
them who are now professors are
in medicine at Buffalo General at
repeating it."
the time and was to be chief medical resident, but I made
The UB professor who inOuenced Farber the most is
the decision to leave for the Mayo Clinic and to move
clearly Earl D. Osborne, who was head of the Departahead with dermatology. "
ment of Dermatology and Syphilology. "He was voted
While at the Mayo Clinic,
the best teacher of the year for
Farber
pursued his scholastic
30 consecutive years; he was
interests, earning a master of scidynamic and exciting," he reence degree at the University of
calls with an enthusiasm that
Minnesota in 1946. He completed
hasn't dampened over the years.
a thesis on the blood vessels in
"Osborne had received his trainthe skin of the essential hypering in dermatology at the Mayo
tensive and immediately made a
Clinic, and he inOuenced me to
contribution to his newly chosen
choose dermatology because I
field by being the first to describe
was so impressed with how he
what is now known as hypertencorrelated clinical changes with
sive ischemic leg ulcer.
biochemical and immunologiThe four years Farber spent at
cal events. That type of apthe Mayo Clinic not only conproach to the largest organ of
firmed his desire to pursue academic medicine, but also
the body had a great deal of appeal to me."
provided him with an opportunity to gain insight into the
Pausing, Farber observes, "Teachers, you know, can
lives of the patients whose suffering he hoped to someday
have a tremendous influence on three or four generations
alleviate through his research.
by virtue of passing on their knowledge, one to another."

In

Oliver
P. Jones

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A Path through an Unexplored Field
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"The Mayo Clinic was the only center in the world
found that Stanford Medical School, which at the time
where they had a program for the treatment for psoriasis;
was in San Francisco, would provide me with a small
they called it the Goeckerman treatment. This involved
lab for dermatopathology research."
covering the patients with black tar from head to foot and
So, in 1950, he headed West, with the promise of a
keeping them in the hospital for a month, giving them
lab , a salary of $2,400 a year and an annual research
ultraviolet light every day and special baths. This caused
budget totaling $50. " obody had any money in those
the disease to go into remission for six months to a year,
days , including the schools; you had to get your own,"
but then it would come back. l was on the hospital service
he explains.
where we had 30 to 40 psoriatic patients who were
But moving west of the Mississippi had its benefits, as
suffering terribly-they were at the 'bottom of the barrel'
he would soon find out. The post-World War II economy
as far as their advanced disease was concerned. When I
was picking up steam and the ational Institutes of
had that experience of taking care of all those patients who
Health ( lH) began to have dollars available to funnel
were suffering so badly, I figured this is what I'm going to
into dermatology research . "There was no research being
do with my research , and that's why I chose to concentrate
done in dermatology in the Western United tates,"
on psoriasis. "
he recalls, "so a representative
Farber says that while working
from the
IH came out and
with the patients during this time,
offered me an opportunity to have
mindhe also gained a deep appreciaa very large grant for research in
tion for the psychological impact
skin
dermatology, if we could provide
of dermatologic disease. "Visible
the labs. " As a result, several thoudisease is the cause of great sufferrelationship is very
sand square feet oflab space were
ing, and diseases of the skin
built and "from then on, we were
require great compassion and
funded generously, not only by
attention to the psyche because of
the IH , but by foundations and
the mind-skin relationship. The
other sources."
mind-skin relationship is very
ln 1959, when Stanford's medistrong, and the morbidity of most
and the morbidity of
cal school moved to Palo Alto,
skin disease is accentuated when
Farber-who had been serving as
most skin diseases is acthere is distress-and I say
a clinical professor and director of
distress , not stress. That is what
centuated when there is
dermatology since 1950-was
the patients experience."
selected as the first chair of the
Fortunately, Farber was able to
school's newly formed Department
play a role in mitigating the sufferof Dermatology, a position he
ing of patients sooner rather than
held until1986. Under his leaderlater. While at Mayo, he had the
ship,
the department grew to
-and I say distress. not
opportunity to work with his chief,
include 11 full-time faculty memDr. Paul O'Leary, to test the effistress. That is what the
bers and achieved international
cacy of the first antihistaminerecognition for its research and
patients
experience.
••
Benadryl-for which Parke-Davis
innovative treatment.
had just received the rights folDuring his long career, Farber
lowing its synthesis in Paris. O'Leary and Farber evaluated
has published more than 250 papers, the majority of which
the compound in acute and chronic urticaria and published
focus on elucidating the natural history of psoriasis and
the first paper reporting the clinical application of the
defining the pathogenesis of the disease. While he was at
antihistamine. "It's been a popular treatment for hives ever
Stanford, the Department of Dermatology sponsored four
since," Farber says.
international conferences on psoriasis, each of which
attracted 300 to 500 dermatologists and basic
Research Opportunities "Out West"
scientists from around the world. Also, in 1967, as chair of
Once his studies at the Mayo Clinic were completed,
the Task Force on Psoriasis for the Academy of DermatolFarber set his sights on winning an academic job in
ogy, Farber and his fellow task force members helped
dermatology. "I was looking for an opportunity to do
standardize treatment of the disease by fulfilling their
scholarly work, but there wasn't anything. Finally, I
charge to evaluate a wide range of treatment modalities in

The

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�use at the time and to establish
criteria for the indications for
the different therapies.
During his busy and productive years at Stanford, Farber also
found time to teach, training over
180 residents and taking pride in
the fact that, despite dermatology
being an elective, 90 percent of all
students signed up to take the
class "because we made it interesting and they were able to have
a close personal relationship with
our faculty," he says.
ln looking back on his role
as teacher, he acknowledges his
good fortune to be in academic
medicine at a time when teaching medical students wasn't circumscribed by economic forces
like those at work in today's
health-care market. "We didn't
have any of the pressures on us
then that managed care imposes
today on faculty , who must see
more and more patients, which
means they have less and less
time for teaching residents and
students," he says. "And teaching in medical schools all over
the country is suffering because of this. "
When he left Stanford in 1986, Farber moved across the
street from the school and opened the nonprofit Psoriasis

INFINITI

Research Institute. Today he
maintains a strong interest in
ongoing research at the institute,
including a large-scale study
under way to find the gene(s)
that predispose individuals to
psoriasis. ever one to retire, he
continues to see patients two halfdays a week because, he says, "I
still enjoy helping people. " He
also enjoys spending time with
his grandchildren and following
the careers of his three children,
Charlotte, an attorney; ancy, a
hospital CEO; and Donald, a
financial consultant.
When he learned that he
had been invited to return to
UB this spring to be recognized
by the university's Alumni
Association , Farber says he
was "honored and absolutely
delighted ," but in recalling
his feelings, he is quick to add
that this is an honor he cannot
accept just for himself: "I have
five siblings who graduated
from UB. l'm very happy with
this honor because I'm thinking of this not so much for
me, but for them, as well. I only wish they could have
been here to share in this, because they certainly deserved
it far more than l." +

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Physician

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��DNG

~OUT

THE

SSTRENGTHSS OF

CHDLDRIEN
Luther Knox Robinson'swork to prevent birth defects
BY JESSICA

ANCKER

HEK LUTHER ROBI SO , MD, traveled to South Africa last
year to study fetal alcohol syndrome (FAS), he heard local people
-.-...-... using the word Ubuntu. They told him it meant "I am because we
are," a powerful expression of the vital importance of the community to
the individual, and of the individual to the community.
The word stuck in his mind because it perfectly conveyed a philosophy that he had long admired. "Each of us has a role to play in
meeting societal challenges," explains the associate professor of pediatrics at the University at Buffalo School
of Medicine and Biomedical Sciences. "Each of us
is successful if the entire group is successful."

Buffalo

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�obinson, who specializes in clinical services for and research
on birth defects, !!opes to draw upon the philosophy expressed
b) ubwzlu to lower the incidence of preventable birth defects like fetal
alcoholS) ndrome. In his view, F AS is not merely a medical condition; it's
a sign of trouble at the heart of a community.
"FAS calls attention to the real challenges \\e have relative to women's

health, and indeed to men's health," Robinson says. "An entire famil) is
affected by alcohol abuse. We need to learn ho\\ to strengthen women
who are involved in substance abuse, and how to help men

to

resist

substance abuse or rehabilitate themselves."
Public education is one of the most
important ways to fight preventable birth
defects. "One cannot guarantee a perfeel baby, but a beller-informed public
can make the types of choices that improve outcomes," he says. "We know
that folic acid is a means oflowering the
risk of spina bifida, and that avoiding
alcohol in pregnancy is a means of
preventing FAS. These are public information issues. "
But with alcohol, education is not
always enough. Society must find ways
to prevent and reduce adolescent entry
into alcohol use and binge drinking, as
research has demonstrated that they are
or will be at high risk for alcohol abuse.
Resources are needed to provide early
intervention counseling, spiritual support or community safe havens to
reduce environmental risk factors.
"We've known about the dangers of
alcohol to the developing fetus for 20 or
30 years now, but the problem of alcohol abuse is so insidious that it's hard to
reach the people who are involved," he
says. "just telling them something is not
going to get them to stop drinking. That's
part of the challenge we have to meet in
our civic lives. "
Robinson tries to put his ideas into
practice not only through teaching, but
also through community leadership and
involvement in local birth-defect infor-

®

mation and monitoring projects. "I am a
believer that one's intellectual work is
enhanced if one can make a link with
one's community.
''I'm not unique in that, in any way,"
he is quick to add. "Most of us at UB feel
that way. "
native of Ohio, Robinson
attended Oberlin College and
.._..o;;...,......-...- earned his medical degree from
the University of Cincinnati College of
Medicine in 1974, after which he completed a residency in pediatrics at the
University of California/San Diego
(UCSD) Medical Center.
It was at UCSD that Robinson met
the physician and scientist who would
set the course of his future career. Kenneth Lyons jones , MD , professor of
pediatrics and dysmorphology, is one of
the first researchers to have identified
and described fetal alcohol syndrome.
jones's 1973 paper in the Lancet, "Recognition of the Fetal Alcohol Syndrome
in Early Infancy," described a cohort of
high-risk children in Seaule and confirmed long-standing suspicions that
alcohol consumed during pregnancy
could cause serious problems, including growth retardation and mental
deficiencies. (A French physician had
published similar findings a short time
earlier, but because his paper was not in

English, it hadn't been noticed by the
worldwide medical community.)
Robinson worked with jones for two
years as a postdoctoral fellow in
dysmorphology. ln addition to learning
about and extending the research on
FAS , he also studied birth defects linked
to genetic factors , nutrition, and chemicals or medications.
Following this experience, he returned to general pediatrics during a
stint as a general medical officer with
the U.S. Public Health Service, and then
served as- an associate professor of
pediatrics at the University of Texas
Medical School in Houston before joining the UB faculty and Children's Hospital of Buffalo in 1987.
Robinson , who is board certified in
both pediatrics and medical genetics, is
director of clinical genetics at Children's
Hospital and serves as part of the teamteaching faculty for the first-year genetics course at UB. He also supervises
residents and fourth-year medical
students doing rotations in the field of
genetics and dysmorphology.

South African child with fetal alcohol syndrome. Her country
has the highest incidence of FAS in the world, according to a
NIAAA study.

�IfF AS is a tragedy,
Robinson is a
at least public educahighly
regarded
tion and other social
teacher who has
and medical methods
earned awards for
offer some hope of preteaching both basic
venting it. With many
science and clinical
of the other types of
subjects
at his
birth defects that
academic posts in
Robinson studies, the
Houston and at UB. In
path to prevention is
1995, he was given the
still uncharted.
johnS. ParoskiAward
Yet Robinson says
for Outstanding Athe does not find his
tending Physician
work disheartening.
Teacher at Children's
Luther Robinson, MD, oHrocts o crowd of children during his visit too village ou~ide Cope Town, South Africa.
First,
he says, there is
Hospital.
He is a regular attending physician Infant Home in the form of the Father the intellectual challenge of trying to
at the Buffalo Institute of Fetal Baker Service to Youth Award in 1991. understand what has happened, a challenge that may someday lead to a cure or
Therapy, the Children's Hospitalobinson's expertise in FAS method of prevention.
based clinic that specializes in detecearned him a place in the
For example, Robinson has been able
tion and treatment (where possible)
ational
Institute
on
Alcohol
show
that facial asymmetry in infants
to
of birth defects in utero. At the instiAbuse
and
Alcoholism
(
IAAA)
delis
linked
to poor facial blood flow durtute, Robinson supervises collection
egation
that
made
two
trips
to
South
ing development. While it's not yet clear
of data for a new birth-defect registry
being created in collaboration with Africa last year. The joint South African how to prevent the problem, the finding
the federal Centers for Disease Con- and American team was studying a re- suggests further areas of research and
trol and Prevention and the ew York gion settled by French wine makers implicates drugs that are known to cause
who for the past 200 years have partici- vascular spasms, such as cocaine, toState Department of Health.
Robinson also serves as medical pated in the "DOP" system, which pays bacco and nicotine. Robinson also finds
director of the Western ew York Tera- their African and "colored" or mixed- satisfaction and inspiration in working
tology Information Service, an organi- race workers with both money and alco- with children.
"l am impressed time and again with
zation he helped found with his wife , hol. The DOP system gives workers wine
jan, a nurse who has long-standing in- two to three times a day, five to seven the strength of children and their famiterests in public health, the prevention days a week, from age 14. This practice lies," he marvels. "They sort of develop
of birth defects and service to the minor- has resulted in the highest incidence of their own realities in the way they deal
ity community. The information service F AS known in the world today, a finding with disability. "
Recently, he saw a former patient, a
answers the questions of pregnant confirmed by the preliminary results of
boy born with limb deficiencies, playing
women who suspect they might have the IAAA's study.
While in South Africa with the hockey. Some of his other patients,
been exposed to a possible teratogen,
provides examinations for their babies delegation, Dr. Robinson examined women who went through high-risk pregchildren from the farm communities nancies as teenagers, are pulling their
and collects data.
The Robinsons founded a similar outside of Cape Town and trained local lives together, caring for their children,
information service in Texas during pediatricians on how to use specific working, or returning to school.
"My work is personally rewarding and
their time in Houston. Both organiza- measurements to identify FAS. "In South
of
materAfrica,
we
find
the
same
types
intellectually
stimulating," Robinson
tions are modeled after a California
service established by Kenneth Lyons nal risk factors we find anywhere- says. "I often say children don't outgrow
jones. The Robinsons' work with the poverty, undereducation, social and their conditions-they outgrow their peWestern New York Teratology Infor- medical problems," he says. "The result diatricians. I look forward to that. I look
mation Service won them recognition is that it is the people with the least forward to working with a second generation of children." +
from Buffalo's Our Lady of Victory resources who are most affected."

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~

I

Biogen Endows Chair in Neurology at UB
LAWRENCE D . JACOBS , MD , PROFESSOR OF NEUROLOGY , TO BE FIRST HOLDER

biotechnology company headquartered in
Cambridge, Massachusetts, has established the Irvin and Rosemary Smith Chair
in Neurology in the University at Buffalo School of Medicine and Biomedical
Sciences through an endowment of 1.5 million.
IOC.I

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The sponsorship of the endowed
chair-which is in conjunction with
Biogen 's 20th anniversary celebrationwas announced by UB president
William R. Greiner at a pres conference
at the university in june.
Lawrence D. jacobs, MD, UB professor of neurology and an internationally
recognized authority on the treatment
of multiple sclerosis (MS), will be the
first holder of the chair (see article

number of MS-related brain lesions and
the number of clinical flare-ups. The
drug , known by the brand name
Avonex®, wa approved by the FDA in
1996 and is now the world's leading
treatment for patients with relapsing
forms of the disease.
In announcing the endowment,
Greiner said, "It is especially gratifying
to have the breakthrough work of one of
our most distinguished faculty memopposite).
bers, Dr. Larry jacobs, lead to the
Currently, MS affects 250,000 to creation of a chair in neurology that
300,000 people in the U.S., with 200 recognizes and supports his work and
new patients diagnosed every week. For provides UB with a permanent legacy.
reasons that are not fully understood,
"Larry's path breaking research, teachpeople who live between the 38th and ing, service and leadership have elevated
52nd northern latitudes on the globe- significantly the national and internaWestern ew York is located at about tional reputation of our Department of
the 43rd northern latitude-a re
eurology and the UB medical school.
particularly susceptible.
We are very grateful to
jacob
was the first
Biogen for recognizing
researcher to show that
Larry's work through this
interferon beta was an
generous gift to UB."
effective treatment in some
james L. Vincent,
forms of the disease. Over
Biogen's chair of the board,
the past two decades, his
said, "Biogen is proud to
pioneering work has been supported by endow thi chair, which honors three
private foundations and the ational individuals who repre ent the fine t
Institutes of Health, with funding for ideals of science. l have been closely
clinical trials provided by Biogen.
associated with lrv and Rosemary mith
Ultimately, jacob's research showed for more than 30 years. They demonthat Biogen's genetically engineered strate the highest standards of courage,
interferon beta-la slowed the accumu- ethical behavior and integrity-values
lation of physical disability in MS pa- that are fundamental to Biogen's corpotients, making it the first treatment ever rate philosophy.
to exert such a benefit for this disease. In
"We are delighted that Dr. Larry
addition, the treatment reduced the jacobs is the first person to hold this

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chair," Vincent added. "His belief in the
potential of interferon beta-la as a
treatment for multiple sclerosis was
vital to the successful development of
Avonex®, which has brought new hope
toMS patients throughout the world."
jacobs said he was "very honored" to
be selected to hold the new Irvin and
Rosemary Smith Chair in eurology.
"The endowment demonstrates Biogen's
commitment to the work we are doing
here, and it's coming at an age when
I still have plenty of time left to continue
that work.
"But the chair isn't forme," he added.
"It's for progres in treating patients
with multiple sclerosis. It will allow us
to do so much, and it will ensure that the
work can continue uninterrupted. "
john R. Wright, MD, interim dean of
the UB medical school, thanked Biogen
for its generosity in endowing the chair
and termed jacobs' appointment as its
first holder "a well-deserved honor.
' ' T h e medical school is proud and
pleased that Biogen has chosen to recognize an individual
who has contributed so much
to the field of neurology and to the
community. Dr. jacobs has spent
more than 20 years helping people
who are living with this debilitating
disease. His work is a great credit to
himself, the UB medical school and all
of the people and organizations who
have believed in him and supported
his research."

Physician

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�owrence D. Jacobs, MD, credits his involvement with the treatment and prevention of
multiple sclerosis-the interest that has
become his life's work-to serendipity.
Anative of Buffalo, Jacobs graduated from
Niagara University and earned his medical
degree from St. louis University. In 1973, he
joined the University at Buffalo faculty as a
clinical assistant professor of neurology.
Through on early affiliation with Roswell Pork
Cancer Institute, where he worked as a consultant,
Jacobs developed a professional relationship with
Arnold Freemon, MD, and several other scientists
who were conducting innovative clinical trials of
interferon as a possible cancer treatment.
It was Freemon who initially urged Jacobs to
begin working with natural interferon, suggesting that he test it to determine its antiviral
and immune-modifying properties in appropriate neurologic patients. In response to this
suggestion, Jacobs decided to concentrate his
interferon research on multiple sclerosis.
"We asked ourselves, What ore the neurologic
diseases of viral and dysimmune etiologies that
might be appropriate for trials of interferon
therapy?" Jacobs explains. "We first considered
lou Gehrig'sdisease, but ultimately we decided on
MS because Buffalo happens to be in a geographic
region where MS occurs with high frequency and
there were so many patients in Western New York
with MS. It was just luck. As it turned out, interferon beto was not effective in treating lou Gehrig's
disease, but it was effective in MS."
Supported by local funding from the Baird
Foundation, Delaware North and UB, Jacobs
began his research. His early results, published in Science in 1981 , reported that interferon injected into
the spinal fluid appeared to stop or reduce MS flare-ups. This led to another, larger multicenter doubleblind study that was supported in port by ogrant from the Notional Institutes of Health (NIH). The positive
results of that trial, confirming those of the earlier study, were published in Lancet in 1986.
By then Jacobs hod the full attention of the NIH; however, in order to secure funding for on even
larger multicenter definitive trial, he knew he hod to show there was o possibility that, in addition to
reducing the number of flare-ups, the drug could slow the accumulation of physical disability naturally
associated with untreated MS.
Jacobs was able to put together o research proposal that satisfied the NIH's stringent requirements
regarding disability, and in 1990 he received $4.5 million over four years to conduct a Iorge study of
interferon's effectiveness in slowing or reversing the accumulation of physical disability in MS patients.
"Biogen then come in to support the Phose Ill trial expenses, as well as the cost of the interferon," Jacobs
says. "We developed o wonderful relationship over the years." The company provided substantial monetary
support and a supply of genetically engineered interferon called recombinant interferon beta-] o needed to
complete the Phose Ill trial. Results of the trial showed that the drug significantly slowed the progression of
disability, decreased the relapse rote and reduced the number of MS-reloted brain lesions, compared with the
placebo group. Avonex®, Biogen's brand nome for the drug, was approved by the FDA in 1996.
Currently, Jacobs is the principal investigator of o$12 million, 50-center study being conducted in the
U.S. and Canada on the potential efficacy of the drug in preventing the development of clinical multiple
sclerosis in patients who ore at high risk for the disease, such as those with optic neuritis. +
-lois Boker

~LVIO.I~ ~~

MD, pioneer
in the fight against multiple sderosis

In addition to
his professorship in
neurology , Jacobs
holds appointments in the UB
Departments of
Ophthalmology,
Physiology, and
Communicative
Disorders and Sciences. He is head of
neurology at the
Buffalo General
Hospital and chief
of neurology at the
William C. Baird
Multiple Sclerosis
Research Center at
Millard Fillmore
Hospital. He has
won numerous
awards and honors
for his work, including the Stockton Kimball Award
in 1996, and has a
lengthy publication record.
Irvin Smith,
PhD , for whom the
chair is named , is
a biochemist by trammg whose
career in health care and biotechnology
spanned nearly 40 years. Prior to his
retirement from Biogen in 1996, he served
as the company's vice president for development operations and was responsible for managing the Phase Ill trial of
Avonex® and for shepherding it through
the lengthy FDA approval process.
Biogen was established in 1978 by a
group of academic researchers, including two obel Prize winners, interested
in genetic engineering and its potential
to improve health care. Discoveries by
Biogen scientists have included the alpha
interferon gene and hepati tis B antigens.
In addition to Avonex®, the company's
discoveries have resulted in the development of Intron® A, a leading treatment
for hepatitis Band C and various cancers,
and of vaccines for hepatitis B. +

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�Refiecting on 40 Years of Service
CHARLES PAGANELLI, DISTINGUISHED SERVICE PROFESSOR, RETIRES

HA.RLES

V.

P A.GA

ELL!, PHD,

Distinguished Service Professor,

and interim chair of the Department of Physiology since 1991,
retired September 1, 1998, after 40 years of service to the University at Buffalo School of Medicine and Biomedical Sciences.
"For the past four decades, Charlie has been a
consistently productive and extremely dedicated
member and leader within this medical school's
faculty, " says Interim Dean john R. Wright , MD.
"His recent elevation to Distinguished Service
Professor rank attests to the many contributions
he has made to the university community and to
the esteem in which his academic colleagues
hold him. As interim chair of the Department of
Physiology, and the newly created/merged
Department of Physiology and Biophysics since
1997, Charlie has demonstrated extraordinary
leadership, patience and vision-qualities we
will surely miss as he enters retirement. "
leon Farhi, MD, Distinguished Professor of
Physiology and Biophysics, says, "Dr. Paganelli's
retirement is a great loss for the university. He has
been a most faithful servant, and his recently being
named a Distinguished Service Professor was longdeserved recognition of his many superb qualities. "
Paganelli came to UB in 1958 after completing
his PhD in physiology at Harvard University and
a two-year postdoctoral fellowship sponsored by
the ational Foundation for Infantile Paralysis at
the University of Copenhagen in Denmark.
In the late 1950s, Hermann Rahn (chair of
physiology at UB from 1956 to 1972) was in the
process of building a department that was to
become internationally recognized for its researchand teaching excellence. Toward this end,
he knew he needed to recruit promising young
faculty and so contacted friends and colleagues
at Harvard and the University of Pennsylvania,
including A. K. Solomon, john Pappenheimer
and Robert Forster, each of whom recommended
Paganelli. Rahn then wrote to Paganelli, offering
him a job at the then University of Buffalo.

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"My wife and I and our
two young children were living in Denmark at the time,
and l accepted the job sight
unseen ," recalls Paganelli,
who adds that he had other
interesting offers but wanted
to return home to ew York.
A native of Brooklyn ,
Paganelli had moved with his family to Albion ,
Y, when he was 12. In 1958 his parents
were still living there , which was one of the
factors that turned the tide in his decision to
come to UB. The other was his opportunity to
join Hermann Rahn in a new and developing
department.
As a student and fellow , Paganelli had focused
his research on examining the permeability properties of red blood cell membranes. "When I got
to UB , my research interests shifted somewhat,
and I became interested in transport in epithelial
cells; for example, in the kidney and in amphibian skin," he says.
Later, Rahn interested Paganelli in studying the
permeability properties of avian eggshells, which
then became his primary focus of research throughout the remainder of his career. This research,
much of which was funded by the National Institutes of Health and the ational Science Foundation, provided a model for studying how gases are
exchanged by diffusion in the lung.
Paganelli credits Rahn with creating a work
environment in the Department of Physiology
that was conducive to creativity, collegiality and
stability-factors, he says, that led him to stay at
UB for four decades. "The department Dr. Rahn
built here was very lively. It was an interesting

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actually been able to introduce them to something they hadn't thought
of before."
ln the mid-1960s,
Paganelli began his long
and notable career of service to the university by
participating in a number of medical school
committees. By the
1970s he was an active
member of several committees for UB's faculty
ofhealth sciences, which
comprised all five ofUB's
medical and health professions schools. Later he
began serving on campuswide committees and was
a member of the Faculty

)

place and he was an extraordinary man.
He had a breadth of interests that was
remarkable, and because his interests
were so broad, he always wanted to share
ideas with you. That's how I got involved
in research with bird eggs. One day he
pulled me aside and said, 'Oh, I have this
project l want to talk to you about,' and
we went from there. He could get you
interested in things." In addition to Rahn,
Paganelli speaks fondly of his many colleagues in the department over the years,
including Don Rennie, Suk-ki Hong and
Leon Farhi.
Upon arriving at UB, Paganelli was also
given the customary load of teaching responsibilities, something which he says
he wasn't quite prepared for at the time.
"When l came to UB, I had only done a
minimal amount of teaching, so l sort of
got thrown into it," he recalls with a smile.
Today, with four decades of experience
behind him, he says without hesitation
that he has very much enjoyed teaching.
"What I have liked about it is the idea that
you can convey concepts to students and
you can see their eyes suddenly open up.
It's a very satisfying feeling to think you've

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Senate , which included a one-year
term on the Executive Committee
and seven consecutive years on the
Budget Committee. He also was a
member of the steering committee
for the self-study that led to UB's
1982 Middle States accreditation.
Paganelli says that perhaps his most
memorable campus-wide assignment
was his chairing of the President's
Review Board on Appointments, Promotions and Tenure (PRB) in the mid1980s. ln a 1997 letter in which he
nominated Paganelli to the rank of
Distinguished Service Professor, UB
president William R. Greiner wrote:

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"Service on this board demands an
extensive commitment of time, as well
as a commitment to the university's
highest ideals. One colleague notes that
Professor Paganelli was 'an exceedingly
effective [PRB] chair who dealt
diplomatically but incisively with very
sensitive matters."'
ln addition to his research, teaching
and service responsibilities, Paganelli
was also given demanding administrative responsibilities. From 1991 until
his retirement, he served as interim chair
of physiology, a role he also fulfilled
from 1980 to 1982 and again in 1986.
He was also associate chair of the
department from 1976 to 1980 and again
from 1982 to 1991.
Paganelli, who is 69, says he and his
wife, Barbara, plan to travel in retirement, as well as spend more time with

their five children and eight grandchildren. Their eventual plans include
living in Italy for an extended period of
time and visiting Hawaii to renew friendships they made in 1974 while on sabbatical at the University of Hawaii.
When asked what he feels about
retiring after 40 years of service to UB,
Paganelli says, 'This has been a very
good place to work. I've had wonderful
colleagues and very good students, and
I've been proud to be affiliated with this
university.
"However, I don't have mixed feelings
about retiring," he adds. "It's time." +
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Inaugural White Coat Ceremony
CLASS OF 2002 REMINDED THAT THEIR MEDICAL CAREERS HAVE BEGUN

swear to fulfill, to the best

r

recited the Class of 2002 as they began the "Physician's Oath" at
the inaugural White Coat Ceremony held in August to welcome
the school's newest medical students.

tremely competitive academic environments where the element of humanism
is often missing, Flanagan adds.

p s he expansion of my knowl·
edge throughout my life for the benefit of my

p
The greatest challenge for medical
ln the presence of faculty, staff, peers, experienced kidney failure a week bestudents
today is that they cannot
family and friends, members of the fore finals as a junior at the University of
school's l52nd class were "cloaked" with California at los Angeles.
anticipate what the
their first white coats to mark the begin- He says he was inspired
medical field will be like
because it is constantly
ning of a new UB tradition that empha- to pursue a career in
sizes the importance of physicians medicine by the compaschanging and evolving,
serving with compassion as well as skill. sion and encouragement
according to Flanagan .
The Arnold P. Gold Foundation, an shown to him by one of
He says that one of the
organization dedicated to fostering hu- the doctors during his hospital stay.
strengths of this year's
manism in medicine , conceptualized the
I ri r me e a t e e s o
and class is the diversity of their academic
ceremony, which reminds new doctors s(e e o die e
and cultural backgrounds , which
Teaching the more personal, psycho- he feels will contribute in a positive
of their responsibility to 'care' as well as
'cure' by endorsing a psychological con- logical aspects of medicine has always way to their ability to adapt to change
tract for professionalism and empathy been a challenge for medical educators, and to continue learning throughout
at the start of their medical catheir careers.
reers. Today, about 85 medical
This year UB received
" WHEN YOU HAVE THIS COAT ON , WHETHER
schools nationwide hold similar
2,500 applications, or about
initiation ceremonies for incom19 applicants per slot.
YOU ARE A STUDENT OR A PRACTICING
ing students.
Thomas Guttuso, MD , assisDOCTOR , YOU ARE EXPECTED TO UPHOLD
. . . I will respect the scientific gains
tant dean and director of
CERTAIN IDEALS . THE CEREMONY REMINDED
of those physicians and scientists in
admissions, says motivation,
whose steps Iwallc, and gladly share
empathy and social awareness
US ALL THAT OUR CAREER STARTS NOW AND
such knowledge as is mine with those
are the qualities that are most
NOT IN FOUR YEARS ."
who are to follow ...
closely evaluated in the
The White Coat Ceremony
Class of 2002
applicants.
A
was an extraordinary way to
Guttuso adds that this
begin medical school, says firstclass, which has 70 women
year student Morcos Morcos. " Reading according to Tom Flanagan, MD , assis- and 65 men , is the first in the school's
the oath reminded us that we're not here tant dean for student and curricular history to have a greater number of
just to pass a class." Marcos adds that he affairs, who organized the White Coat female students. The students range
appreciates the advice he received from Ceremony. "Educators in the medical from age 23 to 35, with the majority
a second-year student who told him that field have done a really good job of of the class between 23 and 26 years of
it's as important to share knowledge in teaching the technology , science and age. Most students majored in science
medical school as it is in medical prac- even the economical aspects of medi- as undergraduates but a substantial4l
tice , and who warned him to be wary of cine; teaching the art of medicine , how- students were non-science majors. The
overly competitive students.
ever, is more difficult. "
mean undergraduate grade point
Morcos, who recently celebrated his
This challenge is compounded by the average of the class is 3.55 overall and
th ird anniversary of a kidney transplant, fact that many students come from ex- 3.5 in science courses.

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••. I will practice medicine with conscience potential partnership in Georgia at the several times in several ways to accomand d1gn f
last minute to pursue her dream of at- modate changes in the medical field,
Margaret Paroski, associate profes- tending medical school.
explains Flanagan.
sor of clinical neurology at UB and the
A few years ago Dennis adler, MD,
e
f my patient
featured speaker at the ceremony, told a
associate dean of the medical school,
the students to be proud of their accomAccording to first-year student requested that a student committee be
plishments in making it to medical Antoinette Alonzo, there are very few oc- formed to review several existing verschool, but to be careful not to become cupationswithasmanyrights. "Wehaveto sions of the oath and to decide on their
arrogant. "The higher the pedestal you're remember that people are entrusting us. own UB version to reflect the modern
on, the harder people try to knock you They are telling us things that they wouldn't world of medicine. The students seoff it," she warned.
lected a brief version of an oath by
tell anyone else."
First-year student
Louis Lasagna, MD,
Deana Savage felt
of Tufts University
Paroski's best advice was
School of Medicine,
to live for today because
which was then
tomorrow is not promadopted as UB's
ised. "Life is today, life
"Physician's Oath."
is now. Don't feel you
... Most especially I
have to wait to start livwill tread with care in
matters of life and
ing until you have finished medical school,"
death. If it be merely
advised Paroski. "Try to
within my abilities to
help ease suffering at
enjoy these next four
the end of a life, may I
years and don' t feel
face this awesome reguilty if you take time to
sponsibility with hudo something you really
mility and awareness
want to do."
of my own frailty ...
The mother of a twoyear-old son, Savage can- Peter Ostrow, MD, associate professor of pathology, helps first-year student Jundo Woo of Brooklyn don her white coot.
ew student
not put life on hold for
Steven Weitzman
four years. "He is actually going to help
Alonzo was in dental school at the Uni- realizes the value of humanism in
me," she says about her son. "lf I ever versity of Pennsylvania when she realized medicine after battling lymphoma while
think about putting off studying, I will she was trying to make dentistry a substi- pursuing his master's degree in
just look at him."
tute for her real passion to study medicine. counseling psychology. Throughout
Savage, originally from Buffalo, is "It gives me a sense of relief and peace of chemotherapy, Weitzman continued
one of 23 UB graduates in this year's mind to be here after having gone through working part-time toward his degree
class and proved her loyalty by submit- something that l knew in my heart wasn't and today is in full remission. Although
ting only one medical school applica- really for me."
he has considered pursuing oncology,
tion. "When I read the acceptance letter,
For Alonzo , the white coat is a mean- Weitzman thinks he may try child
I think everyone in my neighborhood ingful symbol. "When you have this psychiatry since it will not hold such
heard me screaming," she laughs. "The coat on, whether you are a student or a personal relevance.
practicing doctor, you are expected to
excitement still hasn't worn off."
The high point of the White Coat
Of the 139 new students, four are uphold certain ideals. The ceremony Ceremony for Weitzman, he says, was
MD/PhD candidates, three have reminded us all that our career starts when Guttuso read his name and called
already earned doctoral degrees and now and not in four years."
him 'Dr. ' "It made me feel so privier Ican; for leged to be here."
another 14 hold master's degrees in
1e
prev
I vow always to act to preserve the
business administration.
finest
traditions of my calling and may /long
Savage is among those embarking on
The ancient Hippocratic Oath no
a second career. Previously a resident longer accurately reflects what physi- experience the joy of healing those who
podiatrist in Maryland, she gave up a cians do today and has been altered seek my help. +

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�WITH HIS ARTIST AT WORK , SELF-PORTRAIT

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The Artful Doctor

US PROFESSOR ' S PAINTINGS SELECTED FOR INTERNATIONAL JURIED SHOW

E
I '&gt; B f R T R \ \! -physician,
public health specialist and
accomplished scientist at the
University at Buffalo-is ready to
give it all up for art.
Three years ago, the clinical
assistant professor in the Department of
Social and Preventive Medicine
rekindled a love of painting he
had abandoned decades earlier.
When one of his new works was
accepted into an international
juried show earlier this year,
there was no turning back.
"If I could, I would do nothing
but paint," says Bertram, sitting
in the living room of his tum-ofthe-century orth Buffalo home,
where his canvases cover the walls
and cluster in the corners. "But I
can't afford to."
Thus, as with physiciansturned-painters-or - poets
throughout history, science subsidizes
art. Bertram spends mornings at the
School of Medicine and Biomedical Sciences, helping direct the school's new
Master of Public Health Program and its
preventive-medicine residency. In the
afternoons and evenings he takes classes,
paints and applies to art
shows. "My wife tells me
l'm catching up, keeping up
and going ahead all at the
same time," he notes.
Bertram's divergence from
art early on is a telling example of
environment subverting genetics. "Art is
something I wanted to do when I was a
kid," he says. "I was the one who did the
illustrations for the school newspaper and
painted the stage sets in high school.
I even won an art contest.

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"But there was no art education in
my grade school or high school. There
were no role models and I had no encouragement. I was raised to believe in
self-sacrifice, to live life for the betterment of others. To go into art would
have seemed selfish.

"But there was lots of encouragement to go into science," he says. "Lots
of role models, and science offered lots
of opportunity. And I was good at it."
Consequently, Bertram majored in
zoology, no tart, at Indiana University and
earned a medical degree from Washington University. He investigatedartschoolsaftergraduating from medical school,
but didn't have the courage
then to make a major career
change, he says. Instead, he
went to the johns Hopkins University and
earned a master's degree in public health
and a doctorate in science.
For nine years, he was an assistant
professor of social and preventive medicine at UB, conducting health-services
research and publishing papers in scien-

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I

tific journals. Injanuary 1995, he left UB
to manage the technical-information
program locally for The HMO Group,
where he assessed the scientific merit
and effectiveness of medical techniques.
Bertram's wife, Peggy Brooks-Bertram,
assistant to the vice president in the UB
Office of Public Service and Urban Affairs,
inadvertently pointed him back to art.
"It was around Christmas in 1995, and
my wife wanted to do something different
in the foyer for the holidays, so she dragged
out the drawings l did in medical school.
I didn't realize they were still around.
l looked at them and thought,
'Hey! l wasn't so bad! Let merethink this."'
When Bertram left The HMO
Group in 1996 to work as a
consultant, the less-rigid schedule
allowed him time to paint. He
enrolled in art classes at Buffalo
State College and began to draw
and paint again. This time around,
there was plenty of encouragement: He submitted works to an
amateur art show at the Erie
County Fair, winning ribbons and
recognition that spurred him on.
When his painting "At Ease"
(pictured left) was one of 116 pieces out of
l ,500 submissions accepted into the ew
jersey Center for the Visual Arts' 12th
IntemationaljuriedShow, he was thrilled.
The show was juried by an Rosentha,
consultant in 20th-century art to the Metropolitan Museum of Art, and ran from
February 15 through March 29, 1998.
Bertram was e pecially pleased that
his very traditional piece, influenced by
Winslow Homer and Andrew Wyeth,
was selected, despite fitting into neither
of the two movements Rosentha said
characterized most of the selections:
collage and assemblage, and surrealism.
With his talent affirmed, Bertram now
presses on fearlessly. "I no longer have
doubts, as I did when I was younger,
that lam able to do it," he says." ow all
I need is time." +

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"Wimpy"Parents Take Note

inconvenience and failure." The results:
children who often are inconsiderate,
unpleasant, demanding and unhappy.
UB PROFESSOR ' S BOOK ON PARENTING GAINS ATTENTION
Although the rules and relationships
invariably change between parent and
child through the stages that lead to
adulthood, Condrell says underlying
HI- PROC Rf SSI\ f, CHILD-CE TE RED parenting movement,
goals should not. "Early on, it's vital that
popular during the past two decades, has given rise to a youngsters learn to respect authority,
the rights of others and the consequences
national epidemic of families in which children are "running" of their actions. "
Even the very young can learn the
the show, according to child psychologist and family therapist meaning of the word "no" and that
misbehavior, lying, cheatKenneth . Condrell, PhD.
ing , bullying, whining,
Condrell, a clinical assistant professor putting these misobstinance and tantrums
in the Department of Psychiatry at the guided, tired, loving parlead to age-appropriate punUniversity at Buffalo, is coauthor with en ts back in charge of
ishment. Loss of privileges,
Linda Lee Small of a new book, Wimpy their children, their
toys , television, trips or
Parents, From Toddler to Teen: How NOT families and their lives.
games for a predetermined
From fodd. r to Teento Raise a Brat, published recently by
Wimpy Parents, From
HO\\
time carries the message
to Rue
Warner Books. He notes that parents have Toddler to Teen: How
when applied consistently,
a Brat
been encouraged by the "self-esteem moveOT to Raise a Brat
he notes.
ment" to not be strict or bossy with their provides parents with
Condrell stresses that it's
offspring. Instead of being strong family examples and anecalso important to complileaders, he adds, they have become dotes on how to be
ment and reward good
"wimpy" parents, raising kids who are loving and successful paren ts and behavior so a child gets in the habit of
selfish, demanding and disrespectful.
enjoy their children into adulthood.
behaving at home and elsewhere.
The theory followed by these parents
The goal of parents should be to teach
Bratty behavior, if not altered at some
their children a strong point, returns again and again once the
sense of responsibility, children become adults. "They are usu•
worth and values, which ally the adults who will later inconsiderprepares them for the chal- ately drop off their children with
lenge ahead in an often- grandma and grandpa with little or no
changing, demanding, warning to baby-sit, borrow money when
stressful wor ld , says they find themselves in preventable
Condrell. Otherwise, they financial predicaments or expect to
will not grow up prepared routinely be bailed out of self-created
for the real world, where messes," Condrell observes.
proposes that by promoting youngsters' sel [-centered, insensitive, irresponsible
Parents, he says, need to teach their
self-esteem and turning the family into behavior leads to unhappy relationships, children moral values and responsibila democracy, children will grow up to as well as serious and often grave, life- ity through discipline and example, and
be confident, competent, successful threatening consequences.
be firm and loving in doing so. "If they
adults.
"Wimpy parents find it difficult to be don't learn these lessons when they're
"The theory looked good on paper, in charge," Condrell emphasizes. "They
growing up, they'll learn them later from
but in reality, it was awful," says Condrell, are too loving, too patient, take too the real world, which won't be as loving,
who founded and directs a large group much abuse and are wishy-washy where forgiving or supportive," he adds.
practice specializing in family therapy.
discipline and enforcing house rules are
Condrell has appeared on national teleow he and other clinical psycholo- concerned because they want to save vision, including CN and BC-TV's
gists find themselves spending more time their children from unhappiness, Today show.
+

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Innovative Partnership Brings
Gamma Knife to Buffalo
n August 4, 1998, David C. Hahn,
MD , president and chief executive
officer of Roswell Park Cancer
Institute (RPCI), announced the
formation of an innovative partnership with Buffalo eurosurgery
Group, the University at Buffalo's
Department of Neurology and the
Roswell Park Alliance Foundation to
bring to Western ew York a Leksell
Gamma Knife, which he called "one of
the most groundbreaking medical
advances of recent years. "
In announcing acquisition of the
gamma knife, which will be operational
this fall, RPCI becomes the only facility in
Western ew York-and one of only 47
facilities in orth America-to offer this
tool for noninvasive brain radiosurgery.
The purchase of the gamma knife
was made possible through a $3.6 million grant from the Roswell Park Alliance Foundation, chaired by the Han.
Nancy aples.
"This type of
cooperative venture between
private practice,
university
neurosurgeons
and Roswell Park
Cancer Institute
Will be the hallmark of health
care in the 21st century," says L. elson
Hopkins, MD, professor and chair of neurosurgery, and professor of radiology and
director of the Toshiba Stroke Research
Center at the University at Buffalo.
The gamma knife delivers a single,
high dose of ionizing radiation from 20 l
intersecting beams to a target previously defined by advanced imaging techniques. It offers the precision of surgery
Without a scalpel and without the usual
risks associated with surgery, while pro-

viding enough radiation to destroy a
lesion. This form of radiosurgery has
proven successful as a treatment for
benign and malignant tumors and vascular malformations located in critical,
difficult-to-access areas of the brain.
"The gamma knife represents a major technological advance toward
noninvasive treatment, which is rapidly becoming the standard of care for
some of these conditions," says Douglas B. Moreland, MD , director of Buffalo eurosurgery Group and chief of
neurosurgery at Sisters Hospital.
For brain tumor patients who are
not good surgical candidates due to
age, health status , or the inability to
tolerate anesthesia , the gamma knife
may be an alternative to conventional
surgery. For others, it may be used as
an adjunct to conventional surgery.
Following treatment with this state-ofthe-an radiosurgical tool, patients can
usually return to their normal routines
within a day, allowing them to maintain good quality of life while eliminating costly hospital stays.
Between
1988and 1997,
the number of
gamma knife
sites worldwide
has
grown from
five to 112.
Over the same
period , the
number of patients treated has increased each year
from 2,190 in 1988 to 80,000 by 1997.
Gary M. Proulx, MD, radiotherapy
codirector of the Gamma Knife Center,
says, "The gamma knife and other improvements planned for the Brain
Tumor Treatment Center at Roswell
Park Cancer Institute will make the
newest and best treatment modalities
available to patients with malignant and
certain benign diseases of the central
nervous system." +

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In Memoriam

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Student Lounge aSocial Haven
SUPPORT O F MED ICA L A L UMN I A SSO CIATION A PPR ECIATED

hile physicians often prescribe
rest and relaxation for stressprone patients, future doctors
are experiencing the true value
of the therapy in the UB medical
school's student lounge.
Opened in 1993 with the help of the
Medical Alumni Association, what was
once a medical conference room in 133
Cary Hall is now home to the hustle and
bustle of busy medical students who
depend on the room's comforting features
to accommodate their hectic lifestyle.
Visitors to the lounge shouldn't
expect to encounter discussions of gross
anatomy or cell biology so much as heated
foosball games between medical and dental students or a game of pool in which
first-year medical students have challenged more experienced 'second-years.'
Air-conditioned and furnished
with a full-size refrigerator , microwave ,
VCR, televi ion , copier
machine, pool table, two
foosball machines , soda
machines , couches, and
tables and chairs, the
lounge
provides
a
recreational retreat for
hard-working medical students, who
have access to the room 24 hours a day
with a 4-digit security access code.
Second-year students Tom Zajac and
Hugh Bui say they visit the student
lounge to work on their foosball skills.
"lt helps hand-eye coordination in case
you want to go into surgery," jokes
Zajac. Bui sums up what he thinks
about the lounge in three words:
fridge , food and foos.
Cheryl Taurassi, a third-year student,
frequents the lounge mostly to use the
refrigerator and microwave. "The majority of us use it as a place to eat lunch,

®

hang out and take a break, or in some
cases to nap on the couch," she says.
"It's also great in between classes if you
only have 15 minutes or a half hour
unUlyournext c~ss."

The lounge is currently maintained by
POLITY, the medical student governing

alumni affairs in the medical school.
ow retired, Richert recalls when
the lounge area also was the Lippschutz
conference room, which relocated to
the Biomedical Education Building.
Before the lounge was created, he
remembers , the only place students

..
WITH SO MuCH EMPHASIS
BEING PLACED ON EDUCA·

body, whose -ION IN A STRICT SENSE
offices, along
-HE LOUNGE IS A SOCIAL
with those
for the 1ris, HAVEN THAT ENABLES US
the medical TO COMPLETE OUR
student yearT0GETHER
book, are
located
-CHRIS ADAMS
within th e
POLJJY P1rsidrnt
lounge.
The governing board of the UB
Medical Alumni Association played
a primary role in furnishing the
lounge , with the help ofjohn Richert ,
EdD, former associate dean for
Dl'~A~ION

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could hangout socially was in the atrium
in the Biomedical Education Building.
"The students felt the atrium area
was too public , and they wanted something more private that they could call
their own," he recalls. "l agreed, and
POLITY submitted budget proposals
two years in a row to the governing
board of directors. Both yea rs we
designated money to help students
furnish the lounge. "
With the generous donation from the
alumni association, students were able
to purchase couches, tables , chairs, a
television and a VCR.
Bertram Portin , MD , current assistant dean for alumni affairs, adds that

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the alumni association is studentoriented and supportive of enhancing
the quality of student life. "Members
of the association have a genuine
concern for the students' needs and
fee l very strongly that the students
should be taken care of. l was glad to
play a part in making such resources
avai lable," he says.
The lounge is especially important
to students because it allows them a
diversion from the pressures of school.
"It gives us an opportunity to get
away from school work," says
third -year student jason Lake, who was
a regular at the pool table his first two
years, when he participated in
organized lounge pool tournaments.
"If we had no escape , life would get
pretty dull."
To offset the seriousness of their

studies with a little humor, other students turn to television. Popular
programs include stand-up shows of
comedian Chris Rock and reruns of
South Parh, says second-year student
Charmaine Gregory.
Some students, however, use the television as a learning tool. Gregory notes
that she has seen students taking advantage of the VCR to study histology slides
on videotape.
As second-year student Debbie Ogie
busily makes copies, she explains the
convenience the lounge offers students
who want to stay in the building to make
a few copies or to look over material.
"In the winter, people don't like to
have to walk over to Harriman or the
library," she says. "It's also really nice
because it is a place where I can relax
with friends.··

•

According to POLITY president Chris
Adams, the lounge gives students an
opportunity to enjoy each other's
company in a relaxed environment. He
explains that the friendly atmosphere of
the lounge helps foster the development
of interpersonal skills, which are important to being a good physician.
"I feel that the lounge is an integral
part of our experience here at UB. With
so much emphasis being placed on education in a strict sense, the lounge is a
social haven that enables us to complete
our education together ..,
Adams adds, "It's great to see the
dedication of the school's graduates
to the needs of current students.
I think I speak for all of the students
who use the lounge in saying that
the efforts of the alumni are greatly
appreciated." +

\ \}\~c a mistake . But not from the inside .

The roof looks funny, odd, strange, n\\~

1.l1e wa\" IH' sec il. 11 h~· build a &gt;otraight roof 11 hen ~·&lt;nl
ean build a perfeetl1· good erooked one'c
It·, something up to se1·en passengers in the Land
l{o,·er llisem·er1· 11ill trul1· appreeiare.
\\"ith the elenlted roof and stadiumlikc sea tin(\.
passen(\ers in the rear ha1·e ample headroom.

\\' hieh means the~· ean look at more than the hack of the
front seal. ~luch more. in fac1.
Beeause the Land Ro1·er Dbe01·ery ha&gt;o more 11indows
than an1· other 4x4 .
\\'h~· no~ take _one out for a test dril·e'c
.\nd instead ot just looking into it. look out of i!.

48
DISCOVERY

Land Rover Amherst
ANORTHTOWN AIJTOMOlM COWAN'f

3560 Sheridan Drive
Amherst, New York 14226 • (716) 831-3100
http//www.northtownauto.com

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Learning about the Realities of Cancer Care
caring for the patients. My interactions
with the patients became close, and my
with long hours in the lecture halls and laboratories and late concern for each of them deepened. The
nights of study, I eagerly looked forward to summer vacation. Y~t patients' openness with me made me
feel even more concern and sympathy
my eagerness to see summer arrive was not for the typical
for their situations.
reasons, since what I was excited about was beginning a clinical
Full of optimism for each of them,
it shocked me when I would learn from
research program at Roswell Park Cancer Institute.
the attending that a patient's cancer was
The disease of cancer has intrigued Park, my views about quality of life progressing and we had no cure. I would
me since my junior year as an under- have been challenged and redefined. think to myself, "How will we tell the
graduate, when I worked at Yale Cancer In my formerly naive view, I felt that patient? What do we say? " When I
observed Dr. Lawrence
Center. Since that time, my apprecia- when patients or physicians
Leichman talking with pation for oncology has only deepened, in decided to stop treatment or
tients, it was consoling to
large part due to my having had an to not undergo experimental
see how he would indicate to
opportunity to work with two medical therapy at all, they were givthem, either verbally or by
oncologists, Dr. Amy Early and Dr. Meir ing up too ea ily or accepting
his demeanor, that what he
Wetzler, during the past school year. defeat before even trying.
owl understand why somewas about to say would not
Gradually, the field started to have
times
it
may
not
be
worth
much
to
be
easy.
In
fact, he said that if telling
meaning to me beyond the complexities
people such bad news ever becomes
of cancer biology or the therapeutic "fight" anymore, or even try at all.
On most GI clinic days there were easy, it's time to do something else. And
regimen : l began to realize that it's the
end-of-life issues that pose the greatest between 25 and 30 patients. Although he is right. Patients deserve someone
there was a fellow and a resident to who empathizes and is fully supporting
challenge to an oncologist.
Textbooks and manuals will tell you make preliminary assessments of the them during this time. If therapy does
about staging and chemotherapy, but patients, the large number of patients work, the oncologist's care and support
how do you tell omeone that there is no meant that I, too, had an opportunity to may be all the medical hope they have.
It was a challenging summer to
cure for his or her disease? How do you take historic and perform physical exadvise a patient on whether to use ag- aminations. l built confidence and soon face life and death issue so frequently.
gressive treatment or to enjoy his or her felt like an important part of the team On one occasion, l watch ed Dr.
last months in a
Leichman tell a
mother that her 23healthier, asymp tomatic state? There
year-old son might
TEXTBOOKS AND MANUALS WILL TELL YOU ABOUT
live only a few more
arenorightorwrong
answer , nor will it
months. The doctor
STAGING AND CHEMOTHERAPY, BUT HOW DO YOU TELL
told her what she
be the same in every
SOMEONE THAT THERE IS NO CURE FOR HIS OR HER
probabl y already
situation.
knew, but now it
After working for
DISEASE? HOW DO YOU ADVISE A PATIENT ON WHETHER TO
had been confirmed
eight weeks under
that
things were not
the direction of Drs.
USE AGGRESSIVE TREATMENT OR TO ENJOY HIS OR HER
going
to improve.
Lawrence and Gail
In another case,
Leichman in the
LAST MONTHS IN A HEALTHIER. ASYMPTOMATIC STATE?
a woman who had
gastrointestinal
received secondservice at Roswell
pn1

r" ', r.;mc::,T YEA.R OF MEDICAL SCHOOL filled

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HURWITZ &amp; RNE, P.C.
[

line treatment for her colorectal
cancer was told it was not shrinking
the tumor and that there were no more
reasonable options. Sh e could not
appreciate the implications of having
failed the second-line regimen, and
her response to the poor results was
that everything was going to be okay
and the physician would just find
another type of chemotherapy that
would eventually work. But her husband, who was in the hospital room at
the time, understood perfectly.
As we left the room, he followed us
out and asked with uneasiness, "What
do I say to my wife when we get
home? " He did not know how to
cope with the next few days or the
next few months. We had no answers
for him except that we would try to
find another treatment for which she
might be eligible, but explained it was

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highly unlikely that it
would work.
It is not common to
tell someone how long
they have to live, but certain circumstances require it. Patients need to
be aware of what is happening to them so they
can prepare accordingly.
It is usually done out of
respect for the patients
and their families. However, discussing how long
a patient has to live may
not be appropriate because one may not know
the efficacy of treatment
or how fast the cancer will
progress to making a significant systemic impact.
Also, one may unfairly
take away hope for a
patient's survival and
cause him or her to worsen
more quickly due to psychological debilitation.
Sometimes l would stand
in the clinic and wonder, "What are we
accomplishing in oncology? Are we
really helping anyone? "
But then I remember the many faces
we see each day and feel satisfied because I know that regardless of the
outcome, we are supporting these patients through what may be the most
difficult and scary ordeal that they will
encounter. We see the trusting eyes
peering at the doctor, who may give a
glimmer of hope. We also see the insecurity, not knowing if and when the
cancer will come back now that therapy
has been successful.
Every day may bring smiles of denial,
euphoric laughs to cover the hurt, angry
outbursts, silent acceptance or slow
tears. Although oncology is challenging, we help people to cope. And that
may be all that is needed to say that it is
worth it in the end. +

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ATTOR

EYS

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LAW

SERVICI G
THE LEGAL
NEEDS OF THE
H EALTH Scm cEs
CoMMU ITY
• Managed Care
• Purchase &amp; Sale of Practices
• Business &amp; Tax Planning
• HCFA Safe Harbor Regulations
and Physician Self-Referral
• Contracts with Private
&amp; Public Entities
• Employee Relations
Counseling
• Fringe Benefit Programs
• Representation Before
Government Agencies on
Audit &amp; Business Issues
• Facility Finance
and Construction
• C redentialing
and By-Laws
• Hospitai!Medical Staff Issues

Please contact
Robert P. Fine or
Lawrence Mo Ross
at 716-849-8900

1300 Liberty Building
Buffalo. New York

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Body Shape May Indicate
Increased Risk of Breast Cancer
omen who display certain
physical characteristics, such as
abundant body hair, excessively
oily skin and an apple-shaped
physique, may have a greater
risk of developing breast cancer
than other women, researchers at the
University at Buffalo have found.
Results of the research were
presented in june by Paula Muti, MD ,
UB assistant professor of social and
preventive medicine, at the annual
meeting of the Society for Epidemiologic Research .
The finding comes from an analysis
of women who took part in a study
in orthern Italy called ORDETHORmone and Diet Etiology of
Breast Cancer.
Muti says blood levels of male sexual
hormones , called androgens , produced
in women in small amounts by the
ovaries and the adrenal glands, have
been positively associated with the risk
of developing breast cancer in several
prospective studies. The most active
androgen is testosterone.
The current study sought to determine if external signs of high androgen
levels in women could be associated
with brea t cancer risk. A positive finding would mean that these traits could
be used as a screening tool.
"lf these characteristics are linked to
an increased risk , women with these
traits could be referred for closer screening, or could receive treatment to lower
the androgen level," she says. "There
are hormone-lowering drugs available,
and there are also indications that a diet
high in vegetables, fruits and fiber can
lower testosterone levels."

Muti followed a group of pre- andpostmenopausal women in the Italian
study for three years. At the beginning
of the study, the women were assigned
a score based on an assessment of the
amount of body hair. Researchers also
assessed sebum production-the
output of the skin's oil- and waxproducing sebaceous glands-and
body-fat distribution, based on the ratio
of waist-to-hip measurements.
At the end of three years, 36 premenopausal and 26 postmenopausal women
had developed breast cancer. The
remaining participants-136 premenopausal and 99 postmenopausal
women-served as controls.
Analysis of androgenic traits in women
with breast cancer and in those free of
the disease showed that:
• Postmenopausal women with
excess body hair had a 33 percent
increase in risk of developing breast
cancer versus their counterparts with
no excess body hair. There was no relationship bet\&gt;\oeen body hair and breast
cancer risk in premenopausal women.
• Excess sebum production was a significant risk factor for premenopausal
women , but not for postmenopausal
women. Premenopausal women with
the highest levels of sebum production
had 2 lf2 times the risk of developing
breast cancer compared to those at the
lowest level.
• Premenopausal women with the
stereotypical "apple" shape, in which
the waist is bigger than the hips , had a
2112 times greater risk of developing
breast cancer than their counterparts
with "pear" shapes, in which the hips
are bigger than the waist. o signifi-

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cant relationship was found between
waist-to-hip ratio and breast cancer
risk in postmenopausal women.
The results, Muti says, provide more
evidence that androgens play a role in
the development of breast cancer and
show that outward signs of high androgen levels could be a useful screening
tool for the disease .
Martin Stanulla, MD , a visiting researcher from the Medical School of
Hannover, Germany, also participated
in the study. +

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Two Sperm Abnormalities
Linked to Low Pregnancy Rates
link between specific clinical pregnancies and very low levels of two
sperm abnormalities has been
found by fertility researchers at
the University at Buffalo School of
Medicine and Biomedical Sciences.
The two abnormalities-premature
acrosome reaction and premature chromosomal decondensation-are overlooked in a standard semen analysis and
had never been linked to low pregnancy
rates, says Lani]. Burkman, PhD, UB
assistant professor of gynecology and
obstetrics, and urology, and head of the
Andrology Section of the UB Department of Gynecology-Obstetrics.
By analyzing hundreds of semen
samples and comparing them with
subsequent pregnancies in the couples
studied, Burkman and colleagues determined that samples showing more than
7 percent premature acrosome reaction
or more than 14 percent premature chromosomal decondensation had only a
slim chance of leading to a pregnancy.
"We were surprised to see that these
two factors related to pregnancy so
clearly," says Burkman, lead researcher on
the study. "This is a new finding, and it's
impressive because the test is so simple."
The acrosome is an enzyme-filled cap
covering half the sperm head. Just
before fertilization, enzymes from the
acrosome, activated at the proper time,
soften the egg's covering, or zona, and
allow the sperm head with its genetic
material to fertilize the egg. If the
enzymes are released too soon (a
process called premature acrosome reaction) , the sperm is rendered useless.
Premature chromosomal decondensation refers to the untimely unraveling

of the sperm's tightly packed genetic
cargo. lf this begins before the sperm
has penetrated the egg, the sperm
head swells and fertilization becomes
impossible.
"ln our study, when pregnancy
occurred, we knew that the partner's
sperm were capable of fertilizing the
egg," Burkman says. "When pregnancy
did not occur, the possibility existed
that the sperm failed at one or more
points in the fertilization process."
For this study, the results of which
were presented at a meeting of the American Urology Association in June,
researchers analyzed semen samples
from 250 consecutive patients who came
to their andrology laboratory at the
Children's Hospital of Buffalo. Samples
were rejected if the male did not follow
instructions carefully or if the samples
were more than one hour old.
Each sperm slide was scored for
percentage of sperm showing the
premature acrosome reaction or evidence of chromosomal decondensation.
These scores were then correlated with
the couples' pregnancy results, which
were grouped as natural pregnancies,
intrauterine inseminations and in vitro
fertilizations, or no pregnancies.
Results showed a very low incidence
of acrosome reaction or chromosomal
decondensation in the natural pregnancy group, while in the no-pregnancy
group, the rates for both errors were
significantly higher.
Based on these data, the researchers
established fertility thresholds of 7 percent premature acrosome reaction and
14 percent chromosomal decondensation, then tested their criteria on sub-

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sequent new pregnancies. They found
that of the 29 couples who later achieved
a pregnancy, 82 percent fit the new
semen criteria.
"Eighty percent of what we guessed
would happen, happened," Burkman
says. 'This also means that only 20 percent of the problem semen cases could
be linked to a pregnancy. So couples
with either of these errors have greatly
reduced pregnancy potential.
"Fifteen years ago, we knew so little
about the human sperm that we
couldn' t come close to models for
predicting pregnancy," she says. "We
know much more now."
Also participating in the study were
Kent Crickard, MD, Frank Gonzalez, MD,
and Hemlata Bhakoo, PhD, all ofUB and
Children's Hospital, and MaryLou M.
Bodziak of Children's Hospital. +
-LOIS

BAKER

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J .

LINDA

CORDER .

PHD ,

CFRE

AHelpful Guide for Planning
ISITS, PHONE CALLS AND MAIL-these provide much of the communication between the development office and those who are interested in
contributing money, appreciated stock, real estate
or other personal property to the University at
Buffalo School of Medicine and Biomedical
Sciences. Incoming and outgoing communication is
rather even. I enjoy learning from those who love the school
as much as providing information for those who request it.
Recently, one of the school's generous donors passed along
a worksheet on appreciated stock with an example. I had the
occasion to share it with others during the summer. Nov,.·, once
or twice a week, I receive a nev,. request to send it to someone's
friend or classmate, or I am asked for "another copy since I gave
mine away." Something with such widespread interest deserves
a broader audience, so I decided to share it through this column.
What follows is a summary narrative of the procedure, and
then a story. It is offered merely as a guide for planning and for
your enjoyment. As always, when you are ready to make
decisions affecting your taxes, talk with your tax professional.
If you would like more details, please contact me at the office.
Income tax charitable deductions may be claimed for gifts
of intangible capital gain property contributed to the school.
The amount claimed is the fair market value on the date the
assets arc transferred from the donor to the
UB foundation for the school. The overall
deduction of such property is limited to 30
percent of the donor's adJUSted gross income
for that tax year.
To compute an "approximate maximum"
deduction, note your adjusted gross income
from the prior year (assuming no drastic
changes in circumstances), and multiply b)
30 percent ('·x 0.3"). This will give you the
maximum allowable deduction for your
annual income.
To determine the tax benefit of a proposed contribution, multipl) the deduction
by your marginal tax rate to compute your
tax savings. Marginal rates range from 15
percent for incomes under $41,200 to nearly
40 percent for incomes over $2 71,050. Most

®

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of the donors with whom I have worked recently have tax
rates of 31 percent or 36 percent.
If you have a reason to liquidate stock and would like to be
philanthropic rather than pay capital gains taxes, you take the
amount of tax savings on your gift and multiply it by 5. (The
"tax savings" represents the 20 percent figure you would pay
in capital gains taxes.) This number will give you the amount
of personal gain you can obtain using the tax savings from a
gift to offset capital gains taxes you would otherwise pay.
Let's look at Dr. G. I. Feelgood's situation. In 1997, he had
an adjusted gross income of $270,000. Dr. Feelgood also owns
5,400 shares of stock in Small Biotech Laboratories, Inc., which
he acquired over the years with an average cost basis of $3 per
share. SBL never paid a dividend. Currently, it sells for $44 per
share. Dr. Feelgood's holdings are worth $23 7,600-a potential
gainof$221,400. Dr. Fcelgood wouldfeeleven betterifhecould
sell the stock and use the proceeds to pay off his condo in
Arizona. In addition, Dr. Feelgood would feel terrific if he could
use part of the "gains" to benefit good ole' UB medical school,
and at the same time reduce his tax burden.
Dr. Fcelgood figures that he could give a maximum of
$81,000 in stock ($270,000 adjusted gross income x 30 percent)
and save $29,160 in taxes ($81,000 x 36 percent). With the tax
savings and a capital gains rate of20percent, he could also realize
againof$145,800 ($29,160x 5), in essence, tax-free.
A gain of $41 per share is equal to 3,556 shares
($145,800 di\i.ded by $41) for $156,484.
So, the good doctor gives 1,841 shares to UBF
for "alma mater" for a contribution totaling $80,004.
He sells 3,556 shares for $156,464 and pays off his
condo. He is left with three shares of SBL. He will
probably sell them, too, pay Uncle Sam the designated amount and feel ecstatic!
If you have a story, pass it along; or if you have
any reason to sell some of your highly appreciated
stock and would like to contribute an appropriate
amount to offset capital gains taxes, let's talk. +
Linda] Corcle1, PhD, CFRE, is an associate dean in the School
of Medicine and Biomedical Sciences at the Unnerslly at
Buffalo She can be contacted b~ phone at (716) 829-2776;
toll free at 1-877-826-3246; by fax at (716) 829-3395;
or by E-mail, at ljcordcr@acsu.buffalo.cdu.

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LASS OF

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was a
guest speaker at the 24th Annual
University of Wisconsin Spring
Sympo iumsponsored by the Department
of
Ophthalmology
and Visual SciARTHUR J . SCHAEFER '47

1953 REUNION

ences April 1718, 1998,inMadison, WI. His lecture, titled "Reflections on the
Complications of Ptosis Surgery
Yesterday and Today," was given
as a tribute to Dr. Richard K.
Dortzbach, retiring professor of

Cloclmise: Patricia and Harley lindquist, Jack and Maxine Gold, John

Handel, Betty and Samuel Galeota

ophthalmology and director of
the Oculoplastic Service. Dr.
Schaefer is a long-time friend and
colleague of Dr. Dortzbach.
Also, on May 24, 1998,
Schaefer was conferred an
honorary degree of Doctor of
Humane Letters by Canisius
College, whence he graduated
in 1943. In honoring him at this
year's commencement exercises,
the college cited Schaefer's "contributions to the field of ophthalmology, his support for
aspiring physicians, his contributions to church and community, and his outsta nding

Left to right: John B. Fenger, Michael A. Sullivan, Joseph F. Ruh

service to his Alma Mater,
Canisius College."

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peripheral arterial vascular testing and peripheral venous vascular testing. Gage is a fellow of
the American College of Surgeons and serves as a clinical
assistant professor at UB.
JAMES G . EGNATCHIK '79 has
joined Buffalo eurosurgery
Group. He is currently clinical

assistant professor of neurosurgery at UB and a member of the
Executive Committee of the CGF
Health System.

1

DANIEL

is a gen-

eral surgeon and director of the
Main Vascular Laboratory in
Williamsville, NY, which was recently reaccredited by the
lntersocietal Commission for the
Accreditation of Vascular Laboratories. Areas included within
this accreditation are extra-

Left to right: Donald Ehrenreich, James Carlin, Mrs. John Fenger,
Thomas Geoghegan, Rivone Ehrenreich

cranial cerebrovascular testing,

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SCHAEFER

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' 81

authored three chapters in the
textbook Second Edition of Ophthalmic Plastic and RecotJstructive Surge1y, published by C. v.
Mosby earlier this year. The textbook, which covers ophthalmic
plastic, reconstructive and orbital
surgery, is widely read and
referenced in the United States,
as well as internationally.
Schaefer was the
primary author
of the chapter on
enucleation and
the solo author
of the chapters
on evisceration, anophthalmic
socket and socket reconstruction.

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' 90 writes:
and j would
like to announce the birth of our
first child, Zachary Alexander
Bloom, born on August 4, 1998.
GALE

ANDREW B . GAGE '76

9

BURSTE IN

PETER BLOOM ' 90

Peter is a gastroenterologist at
the University ofMaryland. 1am
a pediatrician specializing in
adolescent medicine atthejohns
CONTINUED ON PAGE 36

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.

'
Hopkins School of Hygiene and
Public Health. I recent!) had a
paper published in )AMA (the
lead article, August 12) titled
"Incident CIJ/a111ydia traclw111atis
infections among inner city adolescent females." I received a great
deal of media publicity about the
findings of this paper, including
national (C

, CB ), interna-

tional (CBC), and local TV coverage, as we ll as in magazines (Time,

cwswee/1) and newspapers
(Washington Post, Boston Globe).
WILLIAM

CHLOSTA

'93 will

The combined SUNYAB 14th Annual Research
Day and Buffalo Otolaryngological Society
Meeting was held on June 18, 1998, at the
University Inn and Conference Center in
Amherst, NY. Pictured ore Buffalo-area
physicians honored for their distinguished
contributions in the field of otolaryngology over
the post 40 years. Standing, left to right:
Frederick K. Neuburger, MD; William
Hildebrand Jr., MD '40; William Mcintosh, MD
'45. Seale~ left to right: Irwin A. Ginsberg, MD
'44; Fronk Marchetta, MD '44.

begin his fellowship in cardiathoracic urgery at Yale University/
Yale

ew Haven Hospital injuly

1999. He can be reached a t
chlosta@biomed.med.yale.edu.
APRIL CYR

'98's husband, Kris ,

writes: Aidan Campbell was born

10 ounces. He is already living up

surgeons, practicing at Buffalo

to his name (Aidan means "little

General Hospital, CGF Health

partner of Buffalo Heart Surgical

fiery one" in Irish Gaelic). He

System. A grad uate of the

Associates in 1983.

does tend to sleep quite a bit, so

University of the West lndes,

we're starting to get some sleep

Lewin completed residencies in

ourselves and recover.

general surgery

at Buffalo. He was a founding

IN MEMORIAM
WALTER

L. SYDORIAK

'38.

on july 1, 1998, at 4:05a.m. April

and

bravely endured eight hours of

thoracic surgery

WILLIAM

has been

and a fellowship

August 23, 1998, in St. Mary's

elected president of the Buffalo

in pcdiatriccardio-

Hospital, West Palm Beach,

thoracic surgery

FL. after a long illness. He

at the University

was 78.

labor at Millard Fillmore Hospital. he i doing fine now. Aidan

NORMAN

A .

LEWIN

was pronounced a beautiful baby

Heart

boy and weighed 7 pounds and

specialty of cardiothoracic

urgical Associates, a

cardiaC .

NIESEN

'43 died

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After graduating from UB,
iesen served as a major in the
Army during WWII. He was chief
of urology at Buffalo Veterans
Hospital before entering private
practice in

iagara Falls. Later,

he was chief of the medical staff

ichard F. Mayer '54, professor of neurology

Through I997, Moyer held responsibilities for varied

at the University of Maryland School of Medi-

lengths of lime as director of the Resident Training Program,

cine, was promoted to Professor Emeritus in

acting choir, and director of the EMG and Nerve Conduction

and Mt. St. Mary's Hospital and

I997. On May 9, I998, in celebration of

laboratories and Neuromuscular and Myasthenia Gravis

served as an assistant clinical

Dr. Mayer's long and dedicated career in neurology,

Clinics at the University of Maryland Hospital. He has also

professor of urology at UB.
A member of the Royal Col-

the university held a symposium named in his honor.

published many papers and articles and has participated in

lege of Surgeons of the United

After graduating from medical school at the Univer-

numerous national and international symposia on neuro-

Kingdom,

and chief of urology at

Falls Memorial Medical Center

iesen also main-

tained a practice in

sity at Buffalo, Mayer completed a summer fellowship

muscular disease and neurophysiology.

iagara

iagara

Falls, Ont. He was a past president of the Buffalo Urology

with noted neuroanatomist Grant

Over the course of his long career, Mayer

Rasmussen, PhD, who inspired his growing

has been involved in the training of approxi-

Society and the Health Association of

iagara County. He

fascination with the field of neurology. In

mately I00 neurology residents and 35

moved

Florida 10 years ago.

I 954, Mayer made the decision to go to

fellows in neuromuscular disease and

Survivors include his wife,

Boston to serve a medical internship at the

research. His leaching responsibilities have

jean; a daughter, ancy Eddy of
Palm Beach Gardens, FL; and a

Boston City Hospital. He remained in

brought him great satisfaction, and he enjoys

granddaughter.

Boston for his training in neurology at the

keeping in touch with his former residents

Massochusells General Hospital, with the

Richard F. Moyer, MD

and fellows, who now live and work in locations throughout the United Stales and in

exception of a year when he completed a

to

SIDNEY M. SCHAER '44.

WILLIAM M. BUKOWSKI '47

died

july 28, 1998, after a long baule

fellowship at the Mayo Clinic in Rochester, MN, and

many foreign countries. His travels as visiting professor of

another year when he served as assistant in

neurology have Ioken him to medical centers in Sweden,

research at the Notional Hospital at Queen Square

Denmark, Germany, Taiwan, Great Britain and Columbia.

he had beenastaffmember for44

in london. From I960 through I964, he woso research

For the past eight years, he has made annual trips to Japan,

years. Bukowski, who was an internist and cardiologist, was along-

fellow in neurology at the Harvard Neurological Unit at

where he has served as visiting professor in the department

time clinical assistant professor

the Boston City Hospital and held appointments in

of neurology at Nora Medical University and in more recent

of medicine at UB. He was 76.

neurology ol Harvard Medical School.

years in northern Japan at the University of Hokkaido.

with amyotrophic lateral sclerosis,
in Sisters of Charity Hospital, where

After earning his medical
degree, Bukowski entered the U.S.

In I 966, Moyer accepted a position as associate

As Professor Emeritus, Mayer will continue to leach and

Army Medical Corps as a captain

professor of neurology within the newly organized

consult in the University of Maryland's medical school.

Department of Neurology at the University of Mary-

However, his lighter responsibilities will allow him more lime

and served as commanding
officer of the 57th Field Hospital

land School of Medicine in Baltimore, where he was

for his family and for his weekend retreats on the eastern

in internal medicine and cardiol-

appointed professor of neurology in I 968.

shore of Maryland.

ogy, establishing a private practice
following his military service.

in Toul, France. He specialized

CONTINUED ON PAGE 38

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I

An attending physician in medi-

A professor of gynecology and

cine and electrocardiography at

obstetrics at UB from 1971 to

Sisters Hospital, he was president

1979, Nichols left Buffalo in

of the medical staff there in the early

1980 to become chair of the

1970sand served on the hospital's

Department of Obstetrics and

boardofuusteesfromthemid-1970s

Gynecology at Brown University

to 198l.ln April, he was honored

in Providence. He also served as

as Man of the Year by the Sisters

obstetrician-gynecologist-in-chief

Hospital Past Presidents Club.

at Women and Infants' Hospital of

Survivors include his wife,

Rhode Island.

ichols is credited

Marguerite; five daughters,joan,

with building Brown's academic

Barbara, Kate, Beth ofWashington,

department into a nationally rec-

D.C., and Martha Thomson of

ognized program and for creal-

Devon, PA; two sons, William Jr. of

ing an integrated center for

Montreal and Peter; two brothers,

women's health care throughout

Thomas of Alexandria, VA, and

Rhode Island and surrounding

Stan ley; and eight grandchildren.

states. In 1990, he received the
Distinguished Medical Alumnus

D AVID H . N ICHOLS '47

died in

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CONTINUED ON

PAGE 40

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of UB Foundation Act:IVlties, Inc. All rights reseiVed.

1

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··························································································

I

cine and Biomedical Sciences.

director of the cardiovascular

MICHAEL MEENAGHAN '71,

From 1991 to 1997, Nichols was

laboratory at Memorial Hospi-

fessor

the

ing his career at the University

a visiting professor of obstetrics-

University at Buffalo School of

at Buffalo, he served as direc-

gynecology at liarvard Medical

tal and later became chief of
cardiology.

Dental Medicine and a dental

tor of the dental school's Elec-

School and chief of pelvic

Kucinski was recognized

researcher whose work over two

tron Microscope Laboratories

as a pio-

decades significantly contrib-

and professor and chair of the
former Department of Stoma-

reconstructive
surgery

emeritus

in

pro-

Oral Diagnostic Sciences. Dur-

at

neering

uted to the use and safety of

Massachusetts

h ear t

implants in the human body,

tology and Interdisciplinary

surgeon

died August 31, 1998, in his

Sciences.

and in-

home in Amherst following a

nova tor.

lengthy illness. He was 62.

s

General Hospital , returning to Brown
in 1997 as a

From 1971to 1989, he served
as director of UB's Surface

He was

While many of Meenaghan's

first

studies focused on the design of

until his retirement he was an

cardiologist

dental

in Colorado
Springs to
implant a

biocompatibility of various
materials with oral tissue , he

active member of the Council
on International Studies and

also was involved in evaluating

Meenaghan retired in 1996 as

pacemaker

techniques for "supercleaning"

a Lt. Colonel with the U.S. Army

and to perform heart

various implants for use in the

Reserves , 338th General Hospi-

human body, as well as the

1998, after a six-month battle

tal, Niagara Falls. A graduate of

catheterization and balloon

long-term effects of umbilical-

with lung cancer. He was 61.

American International College

angioplasty; he also invented a

cord vein grafts.

in Springfield, MA, he earned

professor of obstet-

the

lies and gynecology.
CHESTER

5.

KUCINSKI

' 60

died in his Colo-

: submitted by E-mail at:
bpnates@pub.buffalo.edu.

rado
prings
home on April 5,

After completing an internship and residency in internal
medicine at the University of
Minnesota Hospitals , Kucinski
served as a captain in the Army
Reserves on active duty
France

111

from

1962 to 1964.
He then completed his residency in internal
medicine at Washington University in St. Louis , MO, in1965
and a fellowship in clinical cardiology at the University of
Colorado Medical Center in
Denver in 1967.
Kucinski then taught for two
years at Yale University Medical School before becoming
director of cardiology at St.
Joseph'

Hospital in Orange,

heart catheter.

implants

and

Science Center, and from 1991

the

Programs.

As an educator, he had su-

his dental degree and a doctoral

In addition, he established

pervised postgraduate students

degree in anatomical sciences

Flight for Life programs for ru-

and presented lectures in

from UB.

ral areas, conducted cardiology

anatomy for medical and dental

clinics throughout his region

students.

Meenaghan was a diplomate
and past president of the

and recruited the first pediatric

A former chair of the UB den-

American Society of Osseo-

cardiologist to Colorado
Springs. Kucinski started a vol-

tal school's cultural exchange

integration, and a member of

committee and a member of the

the International Congress of

unteer service program that

u ni ve rsi t y-wide

Provost 's

Oral Implantologists , as well

obtained donations of medical

Council on International Stud-

as several professional orga-

equipment. He also traveled to

ies and Programs , Meenaghan

nizations.

Kenya , Morocco , India and

promoted exchange programs

In addition, he was a member

Guatemala to teach modern

with more than 10 foreign den-

of the American Dental Associa-

cardiology practices to medical

tal schools, including those in

tion, the American Association

personnel there.

Thailand, Korea, Japan, China

of Anatomists, the International!
American Association of Dental

Kucinski is survived by

and Mexico. During his career,

his wife, Doris ; two sons,

he was a consultant to more

Research and Omicron Kappa

Bridger of Denver and

than 20 corporate, federal and

Upsilon.

of Colorado

icholas

prings; a daugh-

university agencies, including

Meenaghan is survived by

ter, Megan Guiterrez of Gilroy,

the U.S. Food and Drug
Administration.

his wife, Barbara; four sons,

CA; his mother, Frances of
Buffalo; a brother, Edward

Meenaghan joined the

john

B

and

Michael

of

Williamsville , Kevin of Fort

of Buffalo; two sisters, Sylvia

dental faculty in 1971 in the

Mill,

Krayna of Buffalo and Audrey

lished his practice in Colorado

former Department of Oral Pa-

Lockport; a sister, Kathleen

Tumbarello of

thology . He retired last year as

Springs, where he served as a

Meenaghan of Springfield, MA;

and three grandchildren.

professor in the Department of

and six grandchildren.

CA, in 1971. Inl975 , he estab-

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                    <text>�BUFFALO PH Y SICIAN

Volume 33, Number 3
ASSOCIATE VICE
PRESIDENT FOR
UNIVERSIT Y SERVICES

Dr. Carole Smith Petro
DIRECTOR OF
PUBLICATIONS

Kathryn A. Sawner
EDITOR

Stephanie A. Unger
ART D IRECTOR/ DESIGNER

Alan j. Kegler

STATE UNIVERSITY OF
NEW Y ORK AT BUFFALO
SCHOOL OF MEDIC INE
AND BIOMEDICA L
SCIENCES

Dr. john Wright, Dean
EDITORIAL BOARD

Dr. Bertram Portm, Chai•
Dr. 'VIartin Brecher
Dr. Harold Brody
Dr. Lmda j. Corder
Dr. Alan j. Drinnan
Dr. james Kanski
Dr. Barbara MaJeroni
Dr. Elizabeth Olmsted
Dr. Stephen Spaulding
Dr. Bradley T. Truax
Christopher Adams
Dr. Franklin Zeplowitz
TEACHING HOSPITALS AND
LIAISONS

The Buffalo General Hospnal

Michael Slww
The Children's Hospnal of Buffalo
Erie County Medical Center
Mercy Health System
Millard fillmore Gates Hospital
Millard fillmore Suburban Hospital
Niagara Falls Memorial Medical
Center
Roswell Park Cancer Institute
Sisters of Charity Hospnal
Dennis McCarthy
Veterans Affairs Western New York
Healthcare System

Dear Alumni and Friends,
Buffalo Physician message, sans the "interim"
title. Although I really don't feel much change, it does seem to make a difference
to others in terms of moving things ahead, and that is what is important. I know
that more than a few of you had been urging for a more permanent solution to the
dean's position, and I certainly appreciate the confidence, support and notes of
congratulations that have been expressed.
The dean's office moved in December, to the second floor of the new medical
education building known previously as Cary-Farber-Sherman and now as the
Biomedical Education Building (BEB). The office will be located just off the BEB
atrium, where it will be much more accessible to students. Being tucked back in
the corner of the administrative wing has made it difficult to visit with students on a regular basis.
Indeed, I am in the process of setting up regular lunches with small groups of medical students (twice
a week, God willing) to track how they are doing, on a more personal level. This move will also bring
the dean's office, the Admissions and Medical Education offices into closer proximity.
Speaking of medical education, a special task force has been appointed to look at all four years of
the curriculum. Although this project is expected to take at least two years to complete, we anticipate
some "deliverables" for falll999 implementation and, hopefully, at least, a few "mid-course corrections" this next semester. I talk about these and others changes affecting the medical school in an indepth interview published in this issue of Buffalo Physician (see page 4). Our Dean's Advisory Council
(DAC) recently concluded its fall meeting and the input was most helpful. As with any medical school
in today's turbulent environment, we face a wide variety of challenges and the DAC has proven to be
an invaluable method of reviewing issues and ideas with informed alumni who are dedicated to the
mission of the school. We are also interested in obtaining input from other alumni and I am making
an effort to visit with alumni groups wherever possible. Indeed, at the recent AAMC meeting in New
Orleans, we cohosted a reception (with the other SUNY schools) in an effort to reach out to alumni in
that particular region, as well as to attendees at this national meeting. Unfortunately, we did not see
many alumni who were not also attending the meeting. We shall keep trying, however.
Finally, Dr. Harold Strauss, formerly the Edward 5. Orgain Professor of Cardiology and professor
of medicine and pharmacology at the Duke University Medical Center, arrived at UB on ovember l,
1998, to assume the chair of physiology and biophysics (see related announcement on page 27 of this
issue). This represents a pivotal recruitment, in my opinion, given the importance and stature of this
department within the medical school. Please join me in welcoming Dr. Strauss to our medical school
community. You will learn more about his accomplishments and his plans for the department's future
in upcoming issues of Buffalo Physician.
THIS WILL CONSTITUTE MY FIRST

---;

(_ I &amp;~

~N

~ ~~~~' School of Medicine and Biomedical Sciences
R. W "'G"', MD

©The State University of 'lew York
at Buffalo

Buffalo Physician is published
quarterly by the Stale University of
New York at Buffalo School of
Medicine and Biomedical Sciences
and the Office of Publications. It is
sent, free of charge, to alumni,
faculty, students, residents and
friends. The staff reserves the right
to edit all copy and submissions
accepted for publication.

Dear Fellow Alumni,
THIS PAST FALL, the Western New York medical community received much
attention due to the murder of Dr. Barnett Slepian. Although I did not know Dr.
Slepian personally, he serves as a role model for me and, I am sure, for many other
physicians, as well. He was a man of much integrity and compassion who provided
a wide range of medical services for women in this area. Regardless of each of our
personal opinions regarding abortion, the medical community has a responsibility to provide safe and compassionate care. Medicine has never seemed like a
dangerous profession, yet Dr. Slepian's death reminds us of our vulnerability.
The Medical Alumni Association has chosen "Women's Health Issues" as the
,-(,::,
topic for Spring Clinical Day, May l, 1999 . Mark your calendars now. Thanks to
Dr. Patty Duffner, a dynamic event is anticipated. Treatment advances in the areas of breast and ovarian
cancers will be highlighted. The author and activist Betty Friedan will be the Stockton Kimball lecturer.
Don't miss the opportunity!
Congratulations to our dean, john Wright! Moving the offices of dean within the medical school
walls in order to be closer to where the students are is indicative of his known talent for and interest
in improving the medical school experience here at UB. My confidence in the medical school, and in
the quality of our future graduates, is heightened with Dr. Wright at the helm.

L. M AHER, MD
President, Medical Alumni Association
E LIZABETH

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NUMBER

1_ 9_ 9 _9 '1

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FEB 2 2 1999

LlunAHY
Steady Leadership
in Changing ~mes

2
A

CONVERSATION WITH

.JOHN R. WRIGHT,

12

Managing Mental Health
with Care
RONALD I.

MD,

MD '62,

DOZORETZ,

DEVELOPS LARGEST

Harold Varmus
Delivers Cori Lecture
IN RECOGNITION OF

ROSWELL PARK CANCER

NAMED DEAN IN

PRIVATE

OCTOBER

HEALTH SERVICES COMPANY

ANNIVERSARY

by Scott Thomas

by Catherine Donnelly

1 998

photos by K. C. Kratt

BEHAVIORAL

18

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Major Health-Care lntitiative
U 8

PART OF FEDERAL

PROGRAM TO BRING

HEALTH-CARE PROVIDERS

TO UNDERSERVED AREAS

Medical School

Town Hall Meeting

•

DIRECTOR OF NATIONAL

•

PRIMARY CARE

EXTERNSHIP /

INSTITUTE ON

PRECEPTORS LISTING

ADDICTION, ALAN

INTERNET ACCESS FOR

LESHNER,

RURAL COMMUNITIES

AStudent's Perspective:

Alumni

SEXUAL IDENTITY

•

.JEROME KASSIRER

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CLINICAL

PRACTICE SETTING

PHD,

•

by Frank P. Carnevale, MD '95

.JOSEPH A.

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REUNION WEEKEND!

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JOHN R. WRIGHT, MD, INTERIM DEAN FOR THE UNIVERSITY AT BUFFALO SCHOOL OF MEDICINE
AND BIOMEDICAL SCIENCES SINCE JANUARY 1, 1997, AND CHAIR OF ITS DEPARTMENT OF
PATHOLOGY FOR 23 YEARS, WAS NAMED DEAN OF THE SCHOOL IN OCTOBER 1998.
IN ANNOUNCING THE APPOINTMENT, UB PROVOST THOMAS E. HEADRICK PRAISED WRIGHT'S
CONTRIBUTIONS AS INTERIM DEAN, CITING HIS "EXTRAORDINARY PERFORMANCE IN THE MOST
CHALLENGING OF TIMES FOR MEDICAL SCHOOLS AND HEALTH CARE IN GENERAL."

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�JoHN

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WRIGHT, MD, 24TH DEAN OF THE UNIVERSITY AT BuFFALO ScHoOL OF MEDICINE AND BIOMEDICAL SciENCES.

Michael E. Bernardino, MD, vice president for health
affairs, praised Wright, as well. "john Wright demonstrated
his devotion to the medical school by serving as interim dean
during a very turbulent time. His wisdom, thoughtfulness,
and honest and focused leadership enhanced my transition
to the university, and !look forward to working with him as
we strive to fulfill the mission of the medical school and the
university."

•
perceptive understanding, openness and resoluteness have made it
possible for the university and the medical
school to move for\\·ard toward fundamental
changes during a difficult period,·· Headrick added, lauding
Wright's equanimity, determination and sense of purpose. "I
look forward to his continued help and guidance through the
thicket of concerns affecting health care and medical schools."

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A CONVERSATION WITH DEAN JOHN R. WRIGHT

s Wright embarks on his tenure as dean, he confronts unprecedented business and fiscal
challenges that are inextricably tied to his ability to successfully further the school's
primary mission of educating future physicians and research scientists. In early
November, he took time out of his busy schedule to talk with Buffalo Physician about
some of these challenges and to describe strategies being explored to meet them.
With his long history of leadership at UB in many areas of endeavor, from
teaching and clinical practice to administration and volunteer service, Dean Wright clearly draws on his
deep affection for the school as he strives to provide steady leadership in these changing times.

1In April of last year, Dr. Michael Bernardino assumed the role of vice president
for health affairs at UB. What is the
scope of his responsibilities in relation
to yours as dean of the medical school?

SA

UNGER

with the school's immediate environment, specifically its
education and research missions. Obviously, l too am
concerned with the practice plan since it affects these two
school missions and our overall financial viability. So ,
there are certain aspects of my job that are very closely
intertwined with those of the vice president, and we work
together on these issues.

Until April of last year, the vice president and dean positions were combined,
which is the trend in medical schools
today, particularly in those that own their own hospital.
Our situation, however, is different and probably more
complex than most medical schools. Dr. Bernardino's primary mission will be to work with our affiliated hospital
institutions and managed-care organizations to develop productive working relationships with them and- interwoven
with that mission-to develop a viable practice plan for the
faculty. ln addition , he is also the vice president for the
university's four other health-science schools and so he
must look after their best interests, as well. The medical
school dean, on the other hand, will be more concerned

Why is the Clinical Practice Plan as it
involves medical school faculty being
reorganized?

We have a practice plan that has been
very difficult to operate and oversee for
a reason that is fairly simple: lt was
designed as a one-size-fits-all plan for all
four of the state's medical schools. However, the other three
SU Y schools have their own university hospital, and we do
not. And this situation has made it very difficult for Buffalo to
develop its own workable practice plan.
What has happened is that rather than a
single, centralized plan, we have a practice plan
within each clinical department, and in some
departments there are even additional subdivisions. So we have roughly 22 different practice
plans, each with its own separate corporation,
business manager, billing system, rules and bylaws and so on. In this milieu, how can the
university know what's going on, or negotiate
managed-care contracts? How can we monitor
the entirety of the practice plan to ensure that we
comply with the various regulatory agencies; and
if we are asked for an accounting of the plan, how
can we respond to that request in a timely and
effective way?
Surprisingly, despite this lack of central
Dean Wright (right) works closely with Michael Bernardino, MD, vice president lor health affairs.
organization, the practice plan has worked

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�Ever the professor, Wright lectures on several topics in the General and Systemic Pathology course and says he hopes to continue to be involved in resident education in pathology.

measure of accountability, but we should be able to operate
in a much more efficient way.
In order to be able to contract with the MSO, which is
called UB Associates (UBA) , the departments will all have to
become not-for-profit, "1412," state corporations. Some
already qualify as this kind of entity, but there are other
configurations out there that don't conform and so will
have to change.

rather well over the past decade. But in our particular
environment, the departments have had to be entrepreneurial to a degree that has increased plan variability
from department to department. And, with managed
care, new Medicare regulations, and federal oversight of
Medicare dollars, our system has been stressed enormously. So, where it perhaps wasn't necessary before, it
now becomes imperative that we develop a more
centralized system.

Is there a concern that our practice plan
could be subjected to a federal audit?
What changes are being proposed to
the plan?

The federal audit that is of most concern to us and to every other medical
school in this country is the PATH"physicians at teaching hospitals"audit, which a number of medical
schools and medical centers have already undergone. Basically, these audits grew out of issues surrounding Medicare
billing for physician services and such questions as who
provided the service-residents, who are Medicare supported; or a supervising physician. One of the major issues
has been whether or not the supervising physician was
physically present when a critical part of the service was
rendered. If the physician was not present, then Medicare
contends that he or she should not submit a bill for these
services since Medicare has already paid for the service
through their support of the resident physician. The problem is that, for a long time, Medicare was not at all clear
about what "present" actually meant. This has since been
clarified, in a way, but PATH audits are retroactive in
nature and extend back to when the rules were not clear.

Essentially, what is being proposed is
the establishment of a medical service
organization, an MSO, which will not be
involved in the practice of medicinethat's going to be left up to the individual departments and
their corporations. What the MSO will do is provide
certain services for the departments, such as centralized
accounting and, hopefully, over time, centralized billing,
although the actual preparation of the bills will probably
remain decentralized in the departments. But all the revenues will come in to a central repository so that they can
be accounted for and appropriately credited and then
redirected back to the departments. The MSO will also
provide centralized legal services. Currently, each of the
practice plans has its own legal representation, which has
been an enormous expense for the overall plan, as have
been all the other decentralized services. By forming an
MSO, therefore, we will not only be able to provide some

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One of the ways to monitor these patterns of Medicare
billing is to have more centralized accountability within
the clinical practice plan.

In a recent message in Buffalo Physician, you sa id that the medical
school' s budget continues to represent a challenge, especially in terms
of revenues that are centrally available to operate the school. Could you
elaborate on this?

This concern is not unique to our
medical school. ationwide, managed care has stressed the
clinical side of many, if not all, medical schools. In some
instances, the financial support of the entire enterprise
is challenged.
In our case, the state provides roughly l3 percent of our
expenditures, and the practice plan between 35 and 40
percent, with research grants and endowments making up
much of the remainder.
One of the things we have struggled with in our clinical
enterprise at UB is the fact that we don't have a university
hospital while the other universities in the SUNY system
not only have a hospital that they control, but they are also
subsidized for this facility. In turn, they control their
graduate medical education [GME] dollars, which are
significant. The GME dollars in our system go to the
affiliated hospitals that participate in the GME consortium.
We manage some of these funds through our consortium,
but by no means all of them-or even most of them. As a
result, one of the things UB is known for is that it costs less
for us to educate a medical student than it does for any of
the other state schools. The reason for this is simple: We do
it with fewer resources. One of the ways the whole thing
could be equalized, of course, would be for us to receive a
portion of the subsidy that the other state schools receive
for their hospitals. If we received just a small fraction of
that subsidy and/or had greater control over GME dollars,
we would be in a much better, much stronger, position in
dealing with our affiliated hospitals and in controlling our
educational programs.

Is the medical school looking to obtain
that subsidy?

It's been talked about for a number of
years. I don't want to say that we'll
never get it, as I'd like to think it's a
reasonable request. If we did get that
money, I think we could be a model for

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As choir of the Deportment of Pathology at the University ol Buffalo for 23 years and
immediate post-president of the Association of Pathology Choirs, Dean Wright (pictured here
with graduate student Amy Renauld in the pathology laboratory of Robert Spengler, PhD)
maintains o strong interest in his area of specialty.

the rest of the state-that the state could end up devolving
their university hospitals, which is something they've talked
about; and for a good deal less money than they're spending
now, they could develop a truly excellent medical education system.

Are there advantages to our not
having a university-owned hospital?

ln today's world, it's considered disadvantageous to own one's own hospital, chiefly because of the financial
liability involved. Also, as medical
education and medical practice become less hospital-bound, the value of a highly specialized
tertiary-care facility to a medical school's mission diminishes significantly. The strength of having had, or having
come from , a university-owned hospital, however, is the
"faculty culture" such arrangements facilitate. Without

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that "culture," the full-time faculty do not tend to practice
as a cohesive group and may not identify themselves as
readily with "the university. "

Well, [laughs] we're working through
that. It's a major work in progress and
one that's complicated by the fact that
we have affiliated institutions in the process of undergoing
significant mergers and/or other versions of reorganization. Traditionally, there's been a very competitive spirit
among these institutions, and in today's health-care environment, that competition has only intensified. One result
is the desire, in some instances, to develop more exclusive
relationships with the university.
For example, the CFG system has been seeking and in fact
has publicly pronounced that it wants a more exclusive relationship with the university, yet we at the university also
recognize our other obligations-to Erie County Medical Center, Roswell Park [Cancer Institute], the VA [Veterans Affairs
medical center] and the Catholic Health System-which we're
not going to walk away from. So, we will have to maintain a
delicate balance in terms of exclusivity. That said, however,
I think it's a certainty that we're going to have a very strong
relationship with CGF, but something short of an
exclusive one.
Another very important issue we must address with our
affiliated hospitals is the university's desire, and indeed
need, to control the educational environment for our students and residents. This, of course, presents a challenge
because the hospitals have an equally strong desire to
control the medical services they provide as well as those
who provide them.

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In selecting these centers, we're
building on our strengths. In other words, we're looking
at the areas in which we already have a national reputation and then proceeding to capitalize on these. The
pediatrics and oncology selections clearly fit this stipulation and are areas that we thought, right from the beginning, could be established as Centers of Excellence. As for
when the other centers will be named, I anticipate that this
will take place once the configuration of the medical school
with its affiliated hospitals becomes better defined.

What is the state' s new resource allocation methodology, RAM, and how does
it affect UB' s research efforts?

RAM is a more precise way of allocating resources and reflects upon what
you do and how successfully you do
it. It's an opportunity for UB to garner
more resources from the state, particularly in relationship to new research dollars. There's a sort of premium
applied from the state to research dollars . By that l mean,
for every new dollar that's brought in to the university,
the state has promised to provide us with 20 cents, which
is obviously a very attractive proposition. The problem ,
as I understand it, is that this is a zero-sum game. In

For us, a Center of Excellence will be
nationally and internationally recognized for its clinical services and research expertise in a
specific area of medicine. The medical school, the clinical
centers with which we are affiliated, and the entire geographic region will share in this recognition.

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Two of the Centers of Excellence at UB
have been determined to be pediatrics
and oncology (specifically Roswell Park
Cancer Institute). What are the criteria
for selecting these centers, and when
will the other centers be determined?

It has been announced that UB plans
to establish four Centers of Excellence. What is a Center of Excellence,
and what roles do research, clinical
practice and medical education play
in these centers?

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To develop the type of clinical expertise required for a
Center of Excellence, you need to recruit physicians and
develop programs that have a national reputation and be
able to draw patients from well beyond this region.
To maintain a Center of Excellence, you have to move
forward; you can't simply stand still. You have to generate
new ideas and new knowledge, and to do that, you have to
be engaged in research, both clinical and basic.
From the educational standpoint, nothing stimulates
the development of new knowledge better than questions.
And anyone working with medical students or residents
knows that they make you think about things differently;
they keep you from doing something a certain way simply
because that's how you've always done it.
So, in this way, clinical expertise, research, and medical
education all fit into a common purpose when your goal is
to develop and maintain a Center of Excellence.

How would you describe the present
relationship between the medical school
and its affiliated hospitals? What
changes do you foresee?

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and we need to recognize that these faculty
members are absolutely essential to the educational programs of the school. But we also
need to energetically protect programs that
make us a good medical school.

What are some of the issues
volunteer faculty have with
the university?

One of the main issues is
that volunteer faculty feel
university faculty have an
unfair advantage because
they are "paid by the university." As I said earlier, only 13 percent of our budget
comes from the state, and that is distributed almost equally
between the basic sciences and the clinical departments.
Because the clinical departments are so large, the money
available for salaries is diluted rather rapidly. Also, our fulltime faculty are taxed on their clinical income, which
volunteer faculty are not, and our full-time faculty are
expected to teach and engage in research. Frankly, I see no
such advantage; it's much more of an even playing field than
is generally imagined.
One advantage that I think the university does have-and,
again, this gets back to all of us reading from the same page as
far as the clinical practice plan is concerned-is that we
represent a significant number of physicians in this community and we should be able to apply that strength to managedcare contract negotiations. If we do get our act together and do
function as a group, we'd be a significant presence in this
community and we'd be in a position to provide a conduit
through which volunteer faculty could also benefit from these
contracting relationships. In fact, right now we have a committee of the Governing Board looking at how we might
integrate volunteer faculty who wish to be integrated into the
system so that they can derive additional benefit from a
relationship with the university. As another example, fulltime university faculty can generally obtain malpractice insurance at a much better rate than can the volunteer faculty.
This is an advantage that might also be shared.

Representatives from the Office of Medicol Educotion meeting recently with Dean Wright include
(/eft to right) Fronk Schimpfhouser, PhD, Dennis Nadler, MD, ond Thomas GuHuso, MD.

certain respects, RAM is more a shifting of resources than
a source of much new money. For example, if our productivity goes up in a certain area and another school's
productivity falls , the resources from that declining institution will be transferred to us, and vice versa. If everybody's
productivity goes up in a certain area, there might be little
shift in funds-or new funding.

There' s been some discussion about
university-based physicians establishing clinics in the community. Is this
being considered and, if so, how do
you see this affecting the "towngown " relationship?

Part of the concern about the campusbased University Physicians Offices
[UPO), of course, revolved around the so-called "towngown" relationship. In some ways, the very existence of
physician offices on campus bordered on a tightly held
secret; these were not advertised and there was no large
signage on campus, presumably to avoid some of the
inevitable town-gown issues. But these are issues that are
not going to go away; they're part of the territory for our
medical school, and for most other medical schools.
What we would like to do, however-and I think this is
possible-is to collaborate with volunteer faculty in a
community effort to better distribute our geographic fulltime faculty. These faculty might have office hours at
practice sites that aren't owned by the university, perhaps
in rented space where they could make themselves available to patients and to those volunteer faculty members
involved in our teaching mission.
I feel that this could be a win-win situation for both the
university and the town and an arrangement that could
mute some of the town-gown tensions. After all, we are a
community medical school. We need volunteer faculty

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How would the university benefit from
being in the community?

We need to have a more decentralized
educational system. The number of
hospital beds is shrinking and the push,
particularly in primary care, is to have
students educated where primary care takes place-and

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Medical informatics is also an important part of
modern curriculum development. We have an outstanding new computer lab available to our students,
and we need to ensure that they have "free time"
available to use it.
Currently, we are charging a task force to look at the
curriculum for all four years, but with a "deliverable"
part that can be implemented next fall . Stan Spurgeon, a
faculty member in the Department of Emergency Medicine with a strong commitment to education, is chairing
that committee.

that isn't in a hospital intensive care unit. We're shifting from
a paradigm in which virtually all medical education took
place in a hospital environment, which is a very artificial
environment for primary care, to a more balanced situation
where a good deal of education occurs in the office practice.
So there is definitely an advantage for us to have our
geographic full-time faculty distributed in the community,
with closer working relationships with volunteer faculty.

What is the status of the medical
school's curriculum? Can faculty and
students anticipate
changes?

Yes, they can. We have a
fairly traditional curriculum in this medical school.
Recently, we've added some innovations, such
as problem-based learning [PBL]-the current rage in medical schools-but our core
remains traditional. A number of schools
around the country have revised their curriculum to introduce PBL either in toto or in
part. We're pretty well convinced that there
are some very significant merits to both the
PBL approach and the traditional approach,
so we're striving to develop a hybrid.
A major problem is that by introducing
PBL into the first and second years, we now
have a very crowded curriculum. This is
particularly true for first-year students, who
are in class more than they should be. So we
need to have a more coordinated/integrated curriculum.

Dr. and Mrs. Robert Smolinski, MD, clinical assistant professor of orthopaedics and medical
director of UB' Sports Medicine Institute, enjoy an informal moment with Dean Wright.

BIOGRAPHICAL BACKGROUND
------

~-----

Monitobo, Conodo, John R. Wright received his
medical degree from the University of Monitobo in 1959. He then
served his internship ond o resident yeor in internal medicine ot
Winnipeg General Hospital ond in pathology of Baltimore City Hospitals. In 1964, he completed his residency in pathology of the Buffalo
General Hospital (BGH).
Wright olso wos oNotionollnstitutes of Health fellow in endocrinology
ot BGH ond in 1965 received o two-yeor Buswell Fellowship, which he
spent teaching ond conducting research.
From 1967 to 197 4, Wright served os on ossistont professor of
pathology ond oncology ot the Johns Hopkins School of Medicine. In
1974, he returned to UB to choir its Deportment of Pathology, o position

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he held until being nomed interim deon ot UB in Jonuory 1997. During his
23-yeor tenure os choir of pathology, he olso headed the Deportment of
Pathology of BGH.
Wright hos olso enjoyed o long offiliotion with Roswell Pork Cancer
Institute. From July 1985 through October 1986, he served os interim
director of the institute; he wos olso o member ond long-time choir of its
boord of visitors until it disbanded in1997. Todoy, he remains on the boord
of the Roswell Pork Cancer Institute Alliance Foundation.
Notionally, Wright is immediate post-president of the Association of
Pathology Choirs ond o former member of the Notional Caucus of Bosic
Biomedical Science Choirs ond of the administrative boord of the Council of
Academic Societies of the American Association of Medico I Colleges. +

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James Plott White Society Executive Committee members hosting o congratulatory dinner. Lehto right ore Or. Charles ond Anne Tirone, Oeon Wright ond his wife, Oeonno.

What are some of the attributes you
would like to see in a physician who
his or her medical education

Obviously we would like to make certain that the individual becomes a competent physician with the knowledge
base to enter into whatever postgraduate training program
he or she chooses and the skills, or sense of curiosity, to
continue as a lifetime learner. We would also like to train
physicians who think beyond the pure science of medicine,
who are imbued with the art of medicine and who view
individuals as people first and patients with diseases second.
I think our students tend to come to medical school
very people oriented but somehow we manage to beat it out
of them in the first two years, and maybe in the clinical
environment, as well! We need to pay more attention to
nurturing the attributes they come to us with and to see
that these are not only preserved, but reinforced.

whom I knew quite well, I recall that he was a pretty relaxed
individual [laughs). There were few of the challenges then
that face the deanship today: He was able to go on rounds
with students and we would almost never talk about the
economics of medicine or fiscal or legal oversight. Those
weren't the sorts of things he had to contend with. On the
other hand, medicine itself has advanced enormously, and
we now enjoy the opportunity to teach students many
more exciting things.
In my view, one of the most frustrating parts of medicine
today is the conflict between having the ability to successfully treat a great number of conditions, yet not having
enough resources to provide these treatments to every
citizen in need of them. As dean of a medical school, you
must ask, How will we apportion these gifts, and how do we
fit them into the fabric of our health-care environment and
the bureaucracy within which our graduates will need to
function? Such ethical considerations were not things that
really concerned my dean.

Much of this conversation has been
about change. What is your overall
impression of the health of UB' s medical school and its future?

What are the most pressing challenges you face as dean, and do you
feel this is a particularly diHicult time
to lead a medical school?

I'm an optimist. I think we're going to
go through some difficult times, though.
The construct of the practice plan in

Absolutely! When I think about my
own medical school days and my dean,

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There's going to be a good deal of work ah ead, but we
have the matrix here for success. First of all, we are the only
medical school in the immediate region, which is not a
situation shared by all medical schools. Also, we are a
community-based medical school and I think the larger
community- not just the hospitals but the business community, as well- recognizes the importance of the university and the medical school to Buffalo. And that's a pretty
good asset to have when you're trying to resolve difficult
and contentious issues. +

this medical school never really fit the environment, and
getting that corrected is going to be a challenge. But I
believe it's a very do-able goal.
The competition that is driving the hospitals to change
their configurations is-from the standpoint of progressvery healthy but, on the other hand, we don't want to get
caught in the middle of that competition.
The medical school needs to pursue its own goals and
objectives independently while being aware of and sensitive to the pressures being felt by our affiliated institutions.

MICHAEL BERNARDINO , MD , DISCUSSES

COPING 1111
CHAOTIC ENVIRONMENT

GOALS FOR UB' S MEDICAL SCHOOL

•

R 0 0 UB'svice president for health affairs, presented
areality check on the changes in store for the medical school and its teaching hospitals
in the years ahead at the October 13, 1998, "UB at Sunrise" program.
The inevitable pain that will accompany the changes, he assured the
audience of 170, will be worth the eventual gain.
"Ithink if we con get through the next two to three years, the people of this
community will look bock at the changes and be very, very proud," Bernardino
said. "If we can accomplish even half of our goals, we will hove significantly
improved the quality of care in this community."
Bernardino, whose topic was "How on Academic Health Center Copes in a
Chaotic Environment," took office as vice president for health affairs on
April1 , 1998. He come to UB from Atlanta, where he was director of managed
core with the Emory University System of Health Care, Inc., and professor of
radiology at Emory University School of Medicine.
Bernardino said he has set out to achieve three goals lor the UB School
of Medicine and Biomedical Sciences: (l) sort out the graduate medical
education puzzle with affiliated hospitals to increase benefits to the public
and improve residency programs; (2) increase development and research
revenue; and (3) stabilize clinical revenue.
UB and its teaching hospitals, he added, ore in the process of signing
affiliation agreements, the heart of which pertain to residency traininggraduate medical education-and ownership of the reimbursements-from
insurance providers that fund the training. As the provider of residents to
hospitals and source of a major revenue stream, UB must play a larger role
with the hospitals than in the post, Bernardino contended. "In the future, we
need to be general partners, not a limited partner," he said.
Bernardino predicted that some area hospitals will dose because Western
New York has lor too many beds lor the population, and that the closings will
hove a sizable economic effect. The imperative during these changes, he
stressed, will be to maintain quality of core.

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"UB should serve as a conscience," he said. In terms of quality of care, he
added, "UB physicians should strive to achieve maximal outcomes in 60 to 75
percent of patients, rather than the 50 percent national norm."
In an effort to increase revenue from research and development sources,
Bernardino said the UB School of Medicine and Biomedical Sciences in the
future will locus its clinical and basic research on lour national centers of
excellence.Two obvious areas, he said, are pediatrics and cancer; the remaining
two are still open for discussion.
Noting that stabilizing clinical revenue has been his major locus, Bernor·
dina said that government intervention will be on ever-larger force as increasing numbers of patients ore covered by Medicare and Medicaid. Greater
government involvement, he added, will bring closer scrutiny, in the form of
audits of the medical school's practice plan.
The practice plan is the mechanism by which university-affiliated physicians, under contract with the university, agree to return a certain portion of
their clinical practice revenues to the university to support essential, but nonrevenue producing, aspects of the medical school, such as basic -science
education. In the past, each clinical deportment maintained its own practice
plan.
"In this environment, we can't operate a practice plan in a decentralized
manner with decentralized authority," Bernardino stated.
Underscoring the need to introduce sound-business management, he
added, "We need a corporate mentality rather than a cottage industry mentality. We must emphasize the group needs rather than individual needs."
In the current chaotic health-core environment, Bernardino said, the
medical school must constantly question conventional wisdom and determine its
own path to a new level of stability and excellence.
"I hove no question about our surviving," he said. "I hove no question
about our thriving."
BY

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BAKER

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�Managing

Mental Health
with

UB

ALUM DEVELOPS LARGEST PR I VATE BEHAVIORAL HEALTH SERVICES COMPANY

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DOZORETZ, MD, CLASS OF

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HAPPEN:

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BECAME THE LARGEST I

1962,

IT ALMOST DID 'T

OT THE THRIVI G PSYCHIATRY PRACTICE HE FORMED, WHICH
VIRGINIA, A D

OT THE ME TAL HEALTH

MA AGED-CARE COMPA Y HE FOUNDED, WHICH GREW I TO A MULTIMILLIO - DOLLAR ENTERPRISE ACROSS THE

In fact, if it weren't for the timely
intercession of a caring professor at the
University at Buffalo's school of meaicine, Dozoretz might not even have had
the privilege of becoming a physician.
But that's leaping ahead. To fully
appreciate Dozoretz's faltering start to a
stellar career in health care, it's important to go back to the beginning, to a
little fruit market in Buffalo's Riverside
neighborhood. There, as a boy, he
worked for his parents-his father, an
immigrant from Russia, and his mother,
a lifelong Buffalonian-from a very

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young age. Later, he helped out at the
small supermarket his family opened
off Sheridan Drive.
Work was part of the Dozoretz way of
life, and that ethic extended to education, as well. Throughout his elementary school years, Dozoretz attended
parochial schools and did well; however, when he entered public school, he
discovered he was a grade behind. Determined to catch up to his peers, he
succeeded in graduating from Bennett
High School in three years. He then
pursued studies in biology at the Uni-

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�versity at Buffalo, earning his bachelor's
degree in 1958.
"For kids of that generation who
were smart and really fortunate, medical school was the best opportunity,"
Dozoretz recalls today. "There was dentistry and pharmacy, too, or maybe even
law school," he adds, "but nobody talked
about going into business. It just wasn't
a consideration in those days the way it
is now."

-lJ

ozoretz chose medicine. At
about the same time he
entered UB's medical
school, however, he also
chose to get married to
Marilyn Bass, and the combined stresses
of adjusting to married life and absorbing the enormous amount of material
presented to first-year students almost
proved too much for him to handle.
"With school and marriage, I got stressed
out and started falling behind," he says.
Finally, at the end of that academic year,
three professors-Mouchly Small,
Harold Brody and 0. P. Jones- called
him in and had a candid talk with him:
He would have to get his life in order,
they told him, and repeat his first year
of studies.
"It was a great gift. They could have
thrown me out in a second," Dozoretz
remembers. "But Dr. Small felt that I
was very bright and able to handle the
work, so he gave me another chance. As
it turned out, I went on to finish, and I
think I came out pretty high up in my
class. This clearly had a major impact
on my life-one that I still remember. "
The medical degree Dozoretz earned
at UB opened the door to a remarkable
transformation from doctor to businessman. First came the clinical studies he
conducted with Dr. Julian Ambrose at
what was then Roswell Park Memorial
Institute in Buffalo. Dozoretz had developed a strong interest in hematology,
and at Roswell Park he studied clotting
disorders, work that won him a rotating
internship at Case Western Reserve University in Cleveland. It was there that he
discovered what would become his lifelong calling-psychiatry.

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Ronald I. Dozoretz, MD '62, is chief executive officer, chair and founder of FHC Health Systems.
"I loved the medical part of it," he
says, "and I felt that with psychiatry I
was able to do the medical things that I
was interested in, particularly neurology. And the people in the department

Physician

there were very, very capable. So I
switched specialties."
After three years as a psychiatric
resident at Case Western, Dozoretz
served two years as a lieutenant com-

DESPITE THE CONTINUING SUCCESS OF FHC HEALTH
SYSTEMS, OOZORETZ STILL MANAGES TO FIND TIME TO TURN HIS
ATTENTION TO CHARITABLE AND PUBLIC-SERVICE CAUSES . HE'S
ESPECIALLY PROUD OF A PROGRAM FOR MINORITY STUDENTS HE
HELPED DEVELOP AT NORFOLK STATE UNIVERSITY.

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�In 1982, he sold the company and
began creating what has since become
a sprawling, full-service behavioral
health-care and managed-care company,
FHC Health Systems, headquartered in
orfolk, Virginia. Today, FHC-which
Dozoretz heads as CEO and chair-is
the largest privately held company
providing behavioral health services
throughout the United States and
Canada. With the completion of a recent acquisition , it's also the secondlargest mental health managed-care
company in the nation.
Injune 1998 the company acquired
Value Behavioral Health Inc. and created ValueOptions Inc., which covers
more than 20 million people through
contracts with over 900 customers and
a network of 60,000 providers nationwide. ValueOptions, which operates as
a subsidiary of FHC Health Systems,
manages behavioral and psychiatric

land United States, but to Puerto Rico
and the U.S. Virgin Islands, as well.
FirstLab is the company's international drug and alcohol testing division, serving corporate clients , state
and municipal governments, and even
several professional sports teams. RX
Innovations is a pharmacy benefits
management company with a focus on
behavioral health drug management.
With the creation of ValueOptions,
FHC now employs about 6,000 people.
The company's growth record is a
source of great satisfaction for Dozoretz,
but he prefers to emphasize FHC's goal
of becoming better , not necessarily bigger. It's this ongoing emphasis on costr~ omething else he "had" at that
effective, quality care that has helped
time was the realization that
FHC to form alliances with the Univerhis small practice in Portssity of Virginia and the johns Hopkins
" Jmouth was hamstrung by a
University to conduct outcomes research
........,/ lack of proper facilities for
for treatment of psychiatric illnesses.
his patients. "We basically had a few
"For the past 50 or 60 years, mental
health care has been
rooms in the basement of one of the
provided virtually
FOR MANY, THAT WOULD HAVE BEEN THE HAPPY DENOUEMENT
hospitals ," he rewithout
data ,"
calls. "There was
Dozoretz notes. "It
TO A LONG-SOUGHT-AFTER GOAL, BUT FOR DOZORETZ, IT WAS
no occupational
was conducted in this
ONLY THE BEGINNING . THE ROAD LAY AHEAD, AND IT WAS WIDE
therapy , no recreoffice or that hospiational therapy, no
tal, and maybe thereOPEN. "I'VE ALWAYS HAD AN ENTREPRENEURIAL SPIRIT IN ME.
art therapy and no
sults were published
I JUST THINK YOU EITHER HAVE IT OR YOU DON'T. "
group therapy room.
in a journal article,
It was very difficult
but practitioners
to treat patients. "
rarely spoke with
Dozoretz's solution was to broker a health care in two arenas: in the public each other. There was no one who would
deal with the developer of a nearby sector, through the federal Medicaid compile the data to find out what really
nursing home to establish a psychiatric program and with military contracts; worked in mental health care.
unit in the building. The developer built and in the private sector, through indi"At FHC, we have a significant volit, then leased it back to him. From vidual contracts with dozens of compa- ume of data that allows us to define and
there , Dozoretz expanded the practice nies , including some of the largest in determine what the best treatment plan
to over 125 practitioners in more than the United States.
is for certain types of ailments . With
While ValueOptions is FHC's newest this data , we can help practitioners
10 offices throughout Virginia and became founder and medical director of initiative, the company's other subsidiar- know how to help patients to get better
Portsmouth Psychiatric Center, one of ies have been just as ambitious and just as faster. We also have an extensive inforthe first private psychiatric hospitals in successful. Alternative Behavioral Ser- mation management service division ;
vices manages a wide range of programs it forms the basis of what we do, beeastern Virginia.
Seeing the potential for providing for troubled young people, including al- cause we pay claims to millions of
psychiatric services and facilities , ternative schools, outpatient services, patients and take millions of phone
Dozoretz then founded a company called home and community programs, group calls every day. "
American Medical Centers Inc., and his homes , alternative living programs, teen
By using its vast stores of data to
career as a developer was born. "We "boot camps," secure facilities , residen- structure treatment plans that have
built and developed more than 30 hos- tial centers and acute inpatient facilities. proven, measurable outcomes, FHC has
pitals around the country," he says.
Its reach extends not only to the main- been able to sustain its mission of pro-

mander at the U.S. aval Hospital in
Portsmouth, Virginia , where he treated
inpatient and outpatient service members at the height of the Vietnam War.
"We had two kids , a rented house and
a lot of debt, " he remembers. But he
and his family loved Portsmouth, so
when his time in the service ended, he
established a practice there.
For many, that would have been the
happy denouement to a long-soughtafter goal, but for Dozoretz, it was only
the beginning. The road lay ahead, and
it was wide open. "I've always had an
entrepreneurial spirit in me. I just think
you either have it or you don't. "

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�viding patient-centered care. "We focus
on taking care of patients; this is the
most important thing we do," Dozoretz
stresses. "We don't look at it as a business as much as a service. We're trying
to help people to get better care in a
more organized, cost-effective way.
"Mental health services today are
much more acceptable than they ever
were before," he continues. "If a person
needs help, or his or her daughter, son,
aunt or uncle need it, I think they're
very comfortable asking for it. And the
new medications, such as Prozac and
Clozeril, are extremely effective. They
have changed lives and the way mental
health care is provided. People spend
less time in hospitals now."
Despite the continuing success ofFHC
Health Systems, Dozoretz still manages
to find time to turn his attention to charitable and public-service causes. He's especially proud of a program for minority
students that he helped develop at or-

folk State University. His theory, he says,
is that many minority students are highly
capable of succeeding in the sciences at
the college level, but they may be put off
by the prospect of entering a big college.
At orfolk State, for about a dozen years
now, the Dozoretz ationallnstitute for
Minorities inAppliedSciences has helped
support 20 minority students each academic year. "We've graduated many hundreds," hesayswith pride. "About half go
into medicine and dentistry, half into
other sciences. "
Dozoretz also has instituted a
mentoring program throughout FHC,
in which students at the company's
various offices learn about the healthcare business and receive support and
encouragement from company employees. The program was featured in
President Clinton's recent summit in
Philadelphia, with General Colin
Powell promoting volunteerism in
American life.

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• 36x IDE CD-ROM

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Physic

Dozoretz's public involvement also
has included serving on the White House
Health Reform Task Force, as vice chair
of the Reduction of Bureaucracy Group.
He also serves on the board of trustees of
the Kennedy Center and is a board member of the National Health Policy Council,
where he is active in the restructuring of
the nation's health-care policies.
Dozoretz's home life is full of hopes
and plans for the future, as well. He and
his wife, Beth, have two small children:
four-year-old Josh, and their newly
adopted daughter, Melanne Rose. His
two daughters-Shari and Reneefrom his previous marriage both live
close by.
Acquisitions, outcomes, policies, panels and philanthropy: It all seems like a
long way from the family fruit market on
the West Side of Buffalo. But Dozoretz
still remembers that it almost didn't
happen-except for a second chance that
turned out to be a first-rate decision. +

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(_

was the focus
of the 30th annual Cori Lecture presented at Roswell Park Cancer
Institute (RPCI) on0ctober20, 1998, by Harold Varmus, MD, director
of the National Institutes of Health. This year's lecture was held in
conjunction with an ongoing series of symposia and special events at RPCI in celebration of
the institute's lOOth anniversary (see article on pages 18- 19).
In discussing the future of cancer care, Varmus predicted that "it's quite likely we will learn
HE QCEST FOR! D \ D'

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to tailor cancer therapies to the lesions at the genetic level. Our immediate future will be to
create treatments that target the cellular level of cancer and are widely available to all cancer
patients." He then talked specifically about research he is currently conducting on gliomas,
one of the most common forms of cancer of the central nervous system.
seen in patients with the
most aggressive form of
the cancer.
"In the initial study
Varmus, who shared the
we found that introduc1989 Nobel Prize in
ing mutant bFGF inPhysiology and Medicine
duced proliferation and
with Dr. Michael Bishop
migration of glial cells
for demonstrating that
without the induction of
oncogenes can arise from
tumors. So, we went back
normal cellular genes, exto the beginning and inplained that glioblastoma
troduced mutant VEGF.
multiforme is of particular
::r
Subsequent analysis of
interest to him today. This
the brain tissue found a
poorly differentiated, rapglioma forming in the
idly growing tumor is one
brain," Varmus said.
that occurs most often in
The mice with glioNIH DIRECTOR SPEAKS AT
adults and was the cause of
mas developed hydroROSWELL PARK IN CELEBRATION
death for a colleague of his.
cephalus ; this proOF INSTITU T E ' S 1 00T H
"It has been shown that
nounced swelling of the
15 to 20 percent of paANNIV E RSARY
head will help identify
tients with gliomas reanimals with successful
spond to the conventional
tumor development. A
combination treatment of
magnetic
resonance imBY
CATHERINE
DONNELLY
surgery, radiotherapy and
age (MRI) of the mice
chemotherapy. It is not
with hydrocephalus
clear, however, why some patients respond and the rest
also detected the tumor. These clinical observations will
do not. We decided to seek the combination of genes
allow animals suspected of having a glioma to mature,
that control the mutations seen in these cancer pawhich in turn will enable researchers to study more
tients," he explained.
advanced tumor development.
In order to study the gene mutations ofgliomas, Varmus's
"Our studies matched some of the clinical progreslaboratory used an avian virus-based retroviral vector
sion seen in human patients. It would appear that
system to implant suspected genes into mice. Two genes in
combinations of oncogenes are necessary to create the
particular were studied: basic fibroblast growth factor
migratory gliomas, but this is a good first step. We now
(bFGF) and vascular endothelial growth factor (VEGF).
can move toward the question of where to attack this
More than 90 percent of glioma patients have an abnonnal
disease and which genes consistently cause this canexpression of these genes, and they are predominantly
cer," Varmus reported.

Seeking Genes That
Control Mutations

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Harold Varmus, MD, director of the Nationallnstitues of Health, at Roswell Park Cancer Institute.

Future studies in oncology will not only continue to
expand the list of genetic determinants of cancer but also
explain the function of these oncogenes and their roles in
the process of tumor development. In tum, physicians will
be able to identify the gene causing a tumor and treat it
appropriately, according to Varmus. "We will continue to
build models of human cancer in animals and determine
the genetic changes that cause tumors. It is reasonable to
expect that we will learn the pattern of mutations and gene
expression in cancer and create remedies to cure those
tumors," he predicted.

For the majority of their careers, Carl and Gerty Cori
collaborated on the chemistry of the glycogen-glucose
cycle, work that earned them the 1947 Nobel Prize in
Physiology and Medicine, which they shared with
Dr. Bernardo Houssay of Argentina. With this honor,
Dr. Gerty Cori became the first American woman and the
third woman in the world to be awarded the Nobel Prize.
"The work that Carl and Gerty Cori performed resonates in the scientific community today," Varmus stated.
"They helped us to understand sugar metabolism and its
effect on tumor development, as well as to elucidate the
mystery of diabetes. But, a greater message from their
lives is the need to encourage women in the field and the
incredible results obtained from collaborative efforts. "
Varmus also pointed to an ongoing conflict in the
scientific community between clinical researchers who
need and want to work together on a project and the
tendency in the field to reward independent efforts. "Teamwork," he emphasized, "is the way we need to go." +

The Cort Legacy of Collaboration
In addition to discussing cancer research, Varmus also
stressed the need for collaboration in the scientific field and
recognized the exemplary work of Drs. Carl and Gerty Cori,
who held positions at Roswell Park Cancer Institute from
1922 to 1933 and for whom the Cori Lecture is named.

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University of Buffalo, so a new building was constructed
through fund-raising efforts and the generosity of Mrs.
William Gratwick. In 1901 the Gratwick Research laboratory of the University of Buffalo was opened.
In 1904, Harvey Gaylord, MD, was named the second
director of the institute when Dr. Park stepped down. As part
of this transition, Drs. Park and Gaylord determined that the
laboratory should be owned and managed by New York
State, rather than jointly by the state and the university, as
had been the case since its founding.
"The laboratory was maintained by an annual grant from
New York State, but the state owned neither the land nor the
building-these were owned by the University of Buffalo.
Dr. Park, Dr. Gaylord and other influential administrators
persuaded everyone involved to transform Gratwick Research
Laboratory into a state institute," explains Mirand.
The legislation to transfer the facility was signed on May
10, 1911. The University of Buffalo's Council subsequently
passed a resolution, signed by 14 of its 22 members, agreeing
to transfer the Gratwick Research laboratory to the people
of ew York State on February 29, 1912. The university
received no compensation for the transfer, and the
laboratory was renamed the ew York State Institute for the Study of Malignant Diseases.
The next step in the evolution of the
institute came on March 7, 1912, when a
grant of land and monies was provided for
construction of a hospital on High and Oak
Streets, near the current site of Roswell
Park Cancer Institute. "The time has come
when the State Cancer laboratory should
have hospital facilities for research purposes. All the great modern institutions of
medical research are so equipped,"
stated Gaylord, referring to the fact
that the institute had been using the
Buffalo General Hospital for its patient
care. In 1913, construction was com-

world's first institute dedicated to cancer
research, is celebrating its lOOth anniversary
this year. Since its establishment in 1898 by Dr. Roswell Park,
RPCI has maintained a close relationship with the University at
Buffalo, which played an integral role in its early development.
Park, a world-renowned surgeon, had the prescience to
realize that cancer would become one of the most common
diseases to plague mankind. To confront this challenge, he
proposed the concept of a multidisciplinary institution that
would include research, treatment, follow-up care and education. Soon thereafter, he went in search of funds to launch his
institute, which was destined to become a prototype for
today's comprehensive cancer center.
With the help of Buffalo Evening News editor Edward H.
Butler Sr., Park began by requesting a $10,000 grant from the
New York State legislature. "Dr. Park pioneered the modernday structure of government funding. He believed that New
York State should fund biomedical research and cancer investigations, in particular, although monies for biomedical
research had never before been received from a government
source," explains Edwin A. Mirand, PhD, DSc, emeritus
vice president for educational affairs at Roswell Park
Cancer Institute and author of The Legacy and
History of Roswell Park Cancer Institute.
It took two attempts and an election year to
pressure Governor Frank S. Black to finally
approve the funding from the legislature on
April 29, 1898. The facility, which opened
shortly thereafter, was named the New York
State Pathological laboratory of the University ofBuffalo and was housed on a floor of the
University ofBuffalo, then located at High and
Elm Streets. Its mission, as stated at the
time, was to focus on "defining cancer, its
causes and cures."
Two years after the laboratory was
founded, it outgrew its floor at the

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the New York Pathological
Laboratory of the University
of Buffalo was founded. Its
first home wos on the first
floor of the university, then
located at High and Elm
Streets (/eft).ln 1901, a
separate facility wos built
and named the Gratwick
Research Laboratory

(below). In 1946, the
laboratory was renamed in
honor of Dr. Pork.

passage of the National Cancer Act of 1971 by testifying
at congressional hearings
held at the institute to outline the need for significant
and continued support of
cancer research.
Roswell Park Cancer Institute's relationship with the
University of Buffalo was strengthened again in 1955 under
George Moore, MD , its fifth director, who believed that a
comprehensive cancer center should be involved in education,
particularly graduate education. Moore was joined in promoting this concept by UB president Clifford Furnas; john Payne,
MD, professor of surgery; and Henry Woodburn, PhD, dean of
the Graduate School, who helped to found the Roswell
Park Graduate Division by charter in 1955.
"ln addition, in 1983, RPCI and UB created the Graduate
Medical Dental Education Consortium of Buffalo to jointly
train residents and fellows interested in oncology. Originally,
RPCI had established separate residency and fellow programs,
but it later transferred the programs to the university to maintain their quality and consolidate appointments. To date, RPCI
has helped to train more than 4,000 residents and fellows who
now work throughout the world, and many of the oncologists
in ew York learned from this partnership," says Mirand.
ln May 1998, RPCI unveiled its new Diagnostic Treatment Center and Inpatient Tower. This facility is the
cornerstone of the $241.5 million Major Modernization
Project to renovate the institute's 25-acre campus and
provide a foundation for state-of-the-art cancer treatment
and research into the 21st century.

pleted and Cary Pavilion, a 30-bed hospital, opened at the
institute.
Around the tum of the century, work at the NewYorkState
Institute for the Study of Malignant Diseases was recognized
worldwide and served as a model for cancer research and
treatment across the globe. lts accomplishments influenced
President William Taft, who visited the institute in 1910, to
urge support of a federal cancer program; however, efforts to

.. -

establish a federal cancer program did not gain momentum
again until President Franklin D. Roosevelt was in the White
House. Roosevelt, who understood the goals and programs of
the New York State Institute for the Study of Malignant
Diseases from his years as New York State governor, signed the
first National Cancer Act in 1937, which also established the
ational Cancer Institute.
Almost a decade later, in 1946, the ew York State Institute
for the Study of Malignant Diseases was renamed Roswell Park
Memoriallnstitute in honor of Dr. Park. (In the early 1990s,
its name was again changed to Roswell Park Cancer Institute.)
The institute's influence on national cancer legislation remained strong, and its leaders played an instrumental role in

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...... .............. ...... . . . . . ... . .... . ...... . ...

Initiative to Bring Health-Care
Providers to Underserved Areas
UB HEADS FEDERAL EFFORT I N NEW YORK

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ew York State ranks sixth in the
nation in the number of people
living in areas with fewer than
150 residents per square mile.
Unfortunately, only about one in
3,000 of those persons is a physician, and the ratio is worse in the state's
inner cities.
To help alleviate this shortage of
health professionals in the state's
underserved communities, the School
ofMedicine and Biomedical Sciences
at the University at Buffalo is teaming up with the State University of
New York Health Science Center at Syracuse and other ew
York professional schools.
The effort is being aided by
a three-year, $3 million grant
from the U.S. Department of
Health and Human Services that
funds the first cycle of a 12-year
program with a potential for
$22 million in federal funding.
With the UB medical school as
lead institution, the grant will
fund the start-up of an Area
Health Education Center (AHEC)
program in New York State.
The ew York program is part of
a nationwide effort launched in
1972, based on the 1970 Carnegie
Commission's "Report on Higher

•

Education and the Nation's
Health. " AHEC programs now
operate in 41 states. (An earlier effort in ew York
State failed due
to lack of institutional support.)

The goal of the initiative is to bring
more health-care providers into the
underserved areas by establishing
clinical
teaching
l!Jl~·ml-mlrlJi·mJ•~ . •
and practice sites
in these
outlying
communities or

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urban settings. Each AHEC site will be
managed by a locally appointed director
and advisory board and will be linked
with a medical school.
Through these sites, students from
medicine, pharmacy, nursing, allied
health, dentistry and social
work will get firsthand
experience living among
and caring for patients in
underserved areas.
"We urbanize most of
our medical students during their training," says Thomas C. Rosenthal,
MD, professor and chair of UB's
Department of Family Medicine,
who will oversee the initiative.
"The high-profile urban medical setting is
whatyoungphysicians
are comfortable with,
so that is where they
tend to practice.
"They cluster in
prosperous areas of
cities and suburbs for
personal reasons, also. Most
want to raise families where
they will have the greatest opportunities, so it is difficult to retain
providers in underserved rural communities, in particular. It requires a person
who understands and values rural
America. The only way they will see
themselves in those communities, is to
be in those communities. "
During the program's first three years ,
UB will set up a statewide administrative office in its Department of Family
Medicine and help establish regional
offices at the SUNY Health Sciences
Center at Syracuse and Albany Medical
College/State University of ew York at
Albany School of Public Health.
During subsequent funding cycles,
center staff will help establish AHEC
regional centers at SUNY at Stony Brook
Health Sciences Center and SUNY Health
Sciences Center at Brooklyn. Each regional center will be responsible for

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setting up two community-based AHEC
sites in underserved areas by the end of
the 12-year federal funding cycle. ew
York State is required to begin funding
the AHEC program in its sixth year and
eventually to assume full financial
responsibility.
Diane G. Schwartz, director of special projects for the UB medical school,
will be deputy director of the statewide
program office. During the first year,
the UB office will establish a communitybasedAHEC site in the 14-countyWestern New York region.
According to Rosenthal , each
community-based AHEC will function
as an arm of a SU Y health sciences
center, providing teleconferencing links
back to the main campus, a setting for
meetings with faculty members, and support services to students and residents
living in the rural communities during
their rotations. Site directors and community clinicians who will act as preceptors
will be trained on-site by UB faculty .
"The overall objective is to attract
and keep more health-care workers in
underserved areas, both by linking medical residents and third- and fourth-year
medical students to these communities,
and by helping local practitioners feel
more connected to the SU Y medical
schools," Schwartz says. +

Consortium Effort Looks to
Improve Family Practice
he Department of Family Medicine in the University at Buffalo
School of Medicine and Biomedical Sciences is part of a
university consortium that has
been awarded $900,000 over four
years to participate in a new research
initiative to change the way primarycare services are delivered and assessed.
The grant from the American Academy
of Family Physicians was awarded to the
Center for the Value of Family Practice,
which includes, in addition to UB, Case
Western Reserve University in Cleveland,
University ofN ebraska Medical Center in
Omaha and Lehigh Valley Hospital in
Allentown, Pennsylvania.
The Center for the Value of Family
Practice was one of three centers funded
out of 65 applicants. The award is part of
an $8 million effort undertaken by the
academy to provide a new level of scientific evidence about the importance of
an integrated, whole-health approach
to the practice of family medicine.
"Everyone knows intuitively that
family medicine is highly health-effective
and cost-effective," stated eil Brooks,
MD , president of the academy , in

announcing the initiative. "Countless
stories from the 85,000 members of the
academy confirm that. But a doctor's
anecdotes are not enough. " This effort,
he adds , will lay the groundwork for
evidence-based , outcomes-oriented
research in primary care.
Carlosjaen, MD , associate professor
of family medicine and director of UB's
Center for Urban Research in Primary
Care, is UB's codirector of the project.
"This is very exciting for us ," he says.
"The competition was quite stiff. This
initiative will give us a chance to help
make family practice better for all physicians and patients. "
jaen and his fellow codirectors will
develop a detailed map of the core structures and processes of family practice.
Their center will address five priorities:
• Managing chronic diseases within
the context of each patient's needs
and priorities;
• Increasing the ability of family practice to serve as an outlet for applying
new technologies;
• Integrating mental-health care into
comprehensive medical care;
• Developing practice-tailored systems
to deliver preventive service;
• Increasing the community focus of
family practice. +

Perez Selected to Serve as Liaison to AAFP
each medical school in the United
States to serve as student membership liaison for his or her campus.
The AAFP, a national medical
organization for the specialty of
family practice, represents 85,000
family physicians, family-practice
residents and medical students
nationwide.

renda L. Perez of Buffalo, a second-year student in the University at Buffalo School of Medicine and Biomedical Sciences, has
been selected to serve as student membership liaison for the
American Academy of Family Physicians (AAFP) for the 199899 academic year.
As the AAFP's official UB representative, Perez is responsible for working directly with other medical students who have an
interest in family practice, as well as promoting the specialty of family
practice to fellow students. Each year the AAFP selects one student from

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Physician Preceptors Appreciated
SUMMER 1998 PRIMARY CARE EXTERNSHIP PROGRAM

is an innovative program
that provides real-life clinical learning opportunities for students at the University at Buffalo School of Medicine and
Biomedical Sciences who are interested in pursuing careers in
primary care. Started in 1993 by the Primary Care Resource
Center, the externship is now administered through the Office
of Graduate Medical Education. The program is recognized as the
largest of its kind in the nation by the American Medical Student
Association's Generalist Physician in Training Initiative.
The paid six-week externship, completed during the summer months, exposes both first- and second-year

medical students to the true continuity
of primary care. Placements are arranged
in the offices of generalist physicians

throughout the Western ewYork area.
Students enjoy varying degrees of interaction with patients, including taking
histories and performing physicals, while
becoming part of the daily operation of
an office.
In 1998, newly defined goals and
objectives, along with more detailed
and frequent assessment of the program at various stages, have helped
to strengthen the program by providing a consistent set of expectations
for everyone involved.

The School of Medicine and Biomedical Sciences wishes to extend its thanks to the following
physicians who served as preceptors for the Primary Care Externship Program in 1998:
STUDENT

PRECEPTOR(S)

Dorothy Adler
Sleven J. Ambrusko
Jeffrey L. Amodeo
Lynn M. Barnhard

David Holmes, MD
Jock F. Coyne, MD
Mark R. Klocke, MD
Anthony Vetrano, MD,
lynda S~dhom, MD,
&amp; Josey Welliver, MD
Amy E. Braun
Chelikani V. P. Varma, MD
laura E. Cancilla
Catherine O'Neil, MD,
&amp; Janet Sundquist, MD
Anthony J. Caprio
Richard Ruh, MD,
&amp; Mark Swetz, MD
Shawn Cotton, MD
Thomas V. Caprio
leslie A. Chamberlain Herbert Joyce, MD
J. Thomas Reagan, MD
Jeffrey Chung
Andrea Manyon, MD
Kristin L. Clark
Timothy F. Corvino
Herbert Joyce, MD
Jessica L. Dolewilz
Charles Hershey, MD
Raphael Wang, MD
Sorabh Dhar
Holly J. Drexler
lorne Campbell, MD
Ani J. Fleisig
Donald Robinson, MD,
&amp; Emily Freidan, MD
Jeremy J. Flood
Brian Connolly, MD
Madhuri Guntupalli Gregory Snyder, MD
Brigid M. Hannohoe Jock P. Freer, MD
Ann Marie Hedges
Colleen Mattimore, MD,
&amp; Mary E. Schamann, MD
Alissa J. Huston
Chester Fox, MD
Gregory A. Jobes
David Milling, MD
Christopher W. Kling William Kuehnling, MD

®

STUDENT

Family Medicine
Pediatrics
Pediatrics

Morto C. Kalthoff

Pediatrics
Pediatrics
Internal Medicine
Family Medicine
Family Medicine
Independent Health Admin.
Family Medicine
Family Medicine
Independent Health Admin.
Internal Medicine
Pediatrics
Family Medicine
Family Medicine
Family Medicine
Family Medicine
Internal Medicine
Pediatrics
Family Medicine
Internal Medicine
Family Medicine

a

PRECEPTOR(S)

SPECIALTY

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SPECIALTY

Ashok Noik, MD,
&amp; Suwarna Naik, MD
Internal Medicine
Pat Collins, MD
Family Medicine
Eileen W. Lou
Jennifer I. Lee
Peter Kowalski, MD
Family Medicine
Peter Winkelstein, MD
Sabina lim
Pediatrics
John Thompson, MD
Family Medicine
Andrew G. Moyer
leah S. Millstein
Howard Sperry, MD, MPH, FACP Internal Medicine
lorne Campbell, MD
Family Medicine
Dhruli Naik
Nicholas Aquino, MD
Debra M. Ogie
Medicine/Pediatrics
Bernadette J. Pasamba Geraldine Kelley, MD
Internal Medicine
Peter Kowalski, MD
Family Medicine
Jesenia Pena
Herbert Joyce, MD
Independent Health Admin.
Brenda L. Perez
Elysso R. Peters
Ashok Naik, MD,
&amp; Suwarna Naik, MD
Internal Medicine
Gaurong Sheth, MD
Joey G. Philip
Pediatrics
John Brewer, MD
Everett F. Porter
Family Medicine
Gretchen A. Schueckler Jane M. Parmington, MD
Pediatrics
Davindra Seelagan Thomas S. Scanlan, MD
Internal Medicine
Tracey C. Shanahan Fronk C. Mezzadri, MD
Medicine/Pediatrics
Neha N. Sheth
Theodore Putnam, MD
Pediatrics
Kristen A. Smizzi
Harry Metcalf, MD
Family Medicine
Britto M.Svoren
John Fudyma, MD
Internal Medicine
Rommel M.Tolentino G. lawrence McNally, MD
Pediatrics
Judith A. Toski
Herbert Joyce, MD
Independent Health Admin.
Rosolic Viterbo
G. Jay Bishop, MD, FACP,
&amp; Anthony 0. Bartholomew, MD Internal Medicine
Debra L. Wojtonik
Russell Voughon, MD
Pediatrics
Nora L. Yip
Geraldine Kelley, MD
Internal Medicine

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THROUGH TH E Em oF A STU DE NT . . .

"This past summer, as part of my
Primary Care Externship, I spent six
weeks at a practice, during which
time I not only witnessed the bond
between my preceptor and his
patients, but also formed my own
relationships with patients. I learned
that sometimes when medicine can't
cure things, an understanding and
supportive ear can! This was the most
exciting time in my medical school
career. I experienced many things
and was filled with many confusing
emotions: happiness and sadness,
insecurity and confidence, anger and
serenity. This summer I learned what
medicine is all about. "
Class of 2000

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D oRoTHY A DLER ,

-

P RECEPTOR , D AVID HOLMES , M D

Bailey Family Health Center

CO NTINU ED SUPPORT NEEDED

The Primary Care Externship
Program is currently supported by
a number of sources, including the
Culpeper Foundation, Independent
Health Foundation, Lake Plains
Community Care etwork, Buffalo
General Foundation, and CGF Hospital in jamestown. In order for this
unique program to continue, it needs
the support of the Buffalo community. A special endowment fund has
been established by Evan Calkins,
MD , to develop a more consistent
funding source for the program in
an age of decreasing capital. An
accomplished physician and leader
in the medical community, with a
lifelong commitment to primary-care
medicine, Calkins began the fund to
encourage young people to explore
and pursue the generalist careers.
For more information about the
Primary Care Extemship Program or
giving opportunities, call Susan
Orrange at (716) 829-2802; or E-mail
her at sorrange@buffalo.edu.

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Rural Communities Gain Internet
Access to Health Information
he University at Buffalo Health
Sciences Library has received a
$50 ,000 information-access
project grant from the ational
Institutes of Health and other federal funding agencies. It will be
used to help more than 700 publichealth professionals in rural
upstate communities connect with
the Internet and
acquire access
to a broad
range of health
information
now available
online through
the National Library of Medicine
( LM) and its
affiliated medical
libraries.
The UB project
will serve the
17 counties of
Western and
Central New
York, their county
health departments
and the regional office of the
state Department of Health.
The grant was awarded through a
program called "Partners in Information Access" funded by the LM and its
National Network of Libraries of
Medicine, of which the UB Health
Sciences Library is a member. Other
funding agencies are the Centers for
Disease Control and Prevention, the
Health Resources and Services Administration, and the Association of State
and Territorial Health Officials.
Sharon A. Gray , UB project director,
senior assistant librarian and head of
reference and education services for the
UB Health Sciences Library, says the

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program is designed to increase awareness of the services offered by the
agencies involved. "UB librarians," she
says, "will use their expertise to organize Internet resources on public health
and to teach health department staff to
search these sources effectively. "
Gray says the UB project has targeted
more than 700 public-health professionals for training through workshops. Also,
a Web site linking various information
sites will be developed and
county health department program managers , county
health commissioners and
the Western
ewYork PubHealth Coalition will collaborate on the •
project.
L M

z

director •
Donald ~
A.

B.

Lindberg
says the
projects
funded
will make it possible for publichealth agencies to address a variety of
community health problems and special
populations. They then will be able to
respond more effectively to disease outbreaks and environmental health risks
that affect the health and well-being of
entire communities, he says.
The UB project was designed by Gray;
Maurizio Trevisan, MD , professor and
chair of the UB Department of Social
and Preventive Medicine; Robert O'Shea,
PhD, emeritus professor of social and
preventive medicine; and two of the
department's adjunct professors, Erie
County Health Commissioner Arnold
Lubin and jacques Berlin of the state
health department.
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Honors Brunch Recognizes Firstand Second-Year Achievements
h
s B
recognizing academic excellence
among first- and second-year students was held at the University
at Buffalo School of Medicine and Biomedical Sciences on
October 11, 1998, in Harriman Hall.
The following is a list of award recipients and a description
of the awards received:
received
the Department of
Physiology and Biophysics' Donald W.
Rennie Physiology
Prize, which is given
to the student with
the highest combined
average in the two first-year physiology
courses.
JAY MORROW

DEPARTMENTAL AWAR DS
he departments of the School of
Medicine and Biomedical Sciences have establish ed awards
to recognize meritorious performance in their courses as well as
outstanding achievement in other
curriculum-related activities.

BR'TTA M SVOREN received the Department ofPathology's Komel Terplan Award,
presented to the student with the highest
combined average in the
twosecond-yearpathologycourses. Svorenalso
received the Department
of Pharmacology and
Toxicology's Douglas
S. Riggs Award, presented to the secondyear student with the highest average in
the Fundamentals ofPharmacology course.

received the Department
of Pathology's American Society of Clinical
Pathologists Award for
Academic Excellence,
which is presented to
the second-year student who has demonstrated high academic
achievement and outstanding performance in the pathology laboratory.
ALTER WALEK

M
HORB NSKI received the
Department of Pharmacology and
Toxicology's Edward A. Carr, Jr., Clinical Pharmacology
Award, which is presented to the MD/PhD
student who achieves
the highest average in
the Fundamentals of
Pharmacology course.

CRAG
THOMAS

M

KEENAN

received the Department of Anatomy and
Cell Biology's James
A. Gibson, Wayne ].
Atwell and Oliver P.
Jones Award, which
recognizes the student
with the highest combined average in the
anatomical sciences courses of gross
anatomy, histology, neuroanatomy and
embryology.
CHRISTOPHER ADAMS

received the Department of Biochemistry's Edward L.
Curvish Award, which
recognizes the student
with the highest
average in the two
first -year biochemistry courses.

®

HOPE E CAWDERY received the Department of Microbiology's Ernest Witebsky
Award for Proficiency
in Microbiology, which
is presented to the second-year student with
the highest grade in the
Microbiology and Immunology course.

LIN received first prize for
the Department of Pharmacology and
Toxicology's Astra-Merck Cardiovascular Drug Monograph Awards, which are
presented to the second-year students
based on the quality of
a monograph written
in the form of a package insert. Lin also won
first prize in the
department's 1998 USP
Patient Information
Competition.
JENN FER

MELISSA WOLF received the Department
of Microbiology's Marek Zaleski Award,
which is presented to
the student who best
combines high standards of academic
achievement with
outstanding service to
the community.Each
year's recipient is chosen by members of the second-year class.

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received second prize
for the Astra-Merck
Cardiovascular Drug
Monograph Award competition.
AARON
THO

J.
S

GUYER
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and

received the McGrawHill book awards, which
are presented each year
to the two highestranking students in the
first-year curriculum .
SC

received the Evan Calkins
Primary Care Achievement Award, presented
to an outstanding student
in the Primary Care Summer Externship Program.
s N A PENA received the etter Award,
which is presented to a student fellow for
outstanding performance
in the Primary Care Summer Externship Program.
Pena also received third
prize for the Astra-Merck
Cardiovascular Drug
j Monograph Award comj petition, described above.

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Jennifer Lin
Steven Lo
Todd Loftus
Michael Logue
Beth Lucas
Dionysio Momois
Andrew Moyer
Everett Porter
David Rice
Christopher Santangelo
Tracey Shanahan
Andrew Stone
Moriso Stumpf
Britto Svoren
Cheryl Tourossi
Felicia Tenedios
Rommel Tolentino
Amy Vandewater
Eric Woffner
Wolter Woleck
Nora Yip

Dorothy Adler
Mothijs Brentjens
Anthony Caprio
Thomas Caprio
Daniel Carl
Hope Cowdery
Leslie Chamberlain
Julie Cheng
James Chevalier
Frederic Chi
Joimie DeRosa
Christopher DiMaio
Kimberly Dumoff
Sumo Gono
Rose Graham
Modhuri Guntupolli
Alissa Huston
Adriano Koczaroj
HeyJoo Kong
Brion Klogges
Marta Kalthoff
Sharmeelo Kuperon
Justin Kwon
Charles Lou
Jennifer Lee

) 1

Christopher Adams
John Borgoy
Thomas Botto

Amy Broun
Keith Chon
Damian Compo
Ryan Den Haese
Michael Duff·Roffoele
Sosho Gilmore
Aaron Guyer
Ann Marie Hedges
Steven Kom
Thomas Keenan
Christopher Kling
Somi Lewin
Kevin Mallen
Joy Morrow
Barbaro Odell
Songito Patel
Elysso Peters
David Piccioni
Kilian Salerno
Dovindro Seelogon
Robert Setlik
Mudit Sharma
Koreno Steiding
Robin Yates
Daniel Yoon
Morino Zoydmon

Klagges Completes Alpha Omega Alpha Student Research Fellowship

:l.

rion Klogges, Closs of 2000, was the recipient of on Alpha Omega Alpha
Student Research Fellowship, which provided him with $3,000 in support of
a research project he completed during the summer of
1998 in the laboratory of laura E.Nikloson, MD, PhD,
on instructor of anesthesia at the Massachusetts Gen·
era! Hospital in Boston, Massachusetts.
Under Nikloson's direction, Klogges used a \"Ideo Motion
Analysis System to assist in quantitating the static and
dynamic compliance of culture tissue·
engineered arterial grafts in vitro. He I 8 R 1 A N K L A G G E 5

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(pictured on page 24)

GRET

DEAN'S lETTERS OF COMMEND ATION
he Dean's Letters of Commendation are awarded to students who
achieve 75 percent of available honors points each year. Two
honors points are earned for each credit hour of honors performance; one point is earned per credit for high satisfactory.

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also participated in a preliminary study examining the effects of several
pharmaceutical compounds on the functional characteristics of these engi·
neered vessels.
Klogges graduated cum laude from Providence College in Providence, Rhode
Island, where he double majored in biology and psychology. Alter graduation, he
worked in the laboratory of William Abbott, MD, chief of vascular surgery at
Massachusetts General Hospital.
Alpha Omega Alpha is the only notionalhonor medical society inthe world.
Its purpose is to recognize undergraduate medical school achievement andto
perpetuate excellence in the medical profession.

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•

Multifaceted Approach to
Treatment of Addiction
D I RECTOR OF NAT IONAL INSTITUTE ON DRUG
AB U SE HO L DS TOWN HALL MEET I NG AT UB

he ultimate cure for drug addic- he said , while
tion will probably involve a com- also emphasizbination of biological, behavioral ing the need to
and social considerations, Alan I. make sure these
Leshner, PhD , director of the a- findings are distional Institute on Drug Abuse seminated both
IDA), announced during a recent visit to the practice
to the University at Buffalo.
community and
Leshner's UB visit was one of several to the general
IDA town meetings conducted nation- public.
wide during Red Ribbon Week in
Contrary to
October 1998 to create awareness what most peoabout the realities of drug abuse and ple believe, sciaddiction.
ence "says" that
In a talk titled "Drug Abuse and drug addiction is a preventable problem
Addictions: Myth versus Reality, " and a treatable disease, he maintained.
Leshner clarified common misconcep- "The success rates for drug abuse treattions about the nature of drug abuse and ment are comparable to the success rates
addiction, focused on scientific advances for any other chronic relapsing illness
that have altered researchlike diabetes , hyperteners' fundamental views of
sion and cardiovascular
the problem and anabnormalities. But we can
nounced immediate steps
do better. "
the NIDA is taking to imLeshner also emphaprove treatment.
sized the importance of
Citing drug abuse and addiction as distinguishing between two distinct subamong the most complex phenomena groups of people who abuse drugs:
facing today's society, Leshner acknowl- One group is made up of those who take
edged a tremendous stigma attached to drugs to "feel good, " known as sensadrug addicts and drug addiction. A tion seekers; a second group is made up
further hindrance to the search for work- of those who take drugs to "feel better,"
able treatment approaches, he added, or as a form of self-medication. Essenis the fact that so many misconceptions tially, both groups "like what drugs do
abound.
to their brains. Although, in the past, a
"We have ideologies galore that exist problem has been that we lumped evabout the phenomenon; luckily, how- eryone together both in prevention and
ever, we now also have scientific data. " in treatment. "
Advances in science over the past 20
Leshner showed slides of functional
years have revolutionized fundamental MRI scans depicting increased activity
views about drug abuse and addiction, in the brain's reward circuit after drug

®

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use , noting that this area of the brain has
traditionally been the focus of studies.
Recently , however, researchers have
begun to look at how drugs and drugassociated stimuli relate to a wide
spectrum of brain functions , such as
emotional memory, he reported.
Drug addiction is fundamentally a
brain disease: Drug use alters the brain
state and, over time , actually causes
brain changes that result in the compulsion addicts experience, Leshner said.
"Compulsion, which is the essence of
addiction, occurs because drug use over
time changes the brain in ways that
persist long after the individual stops
using drugs. Treatment needs to attend
to those brain changes, both pharmacologically and behaviorally.
"Drug addiction is not just about
moral weakness and failure , as many
people want to believe," he continued.
"The final common path for addiction is
the brain, but when and how one becomes addicted depends on an intersection of elements, including genetics. "

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"COMPULSION, WHICH IS THE ESSENCE OF ADDICTION, OCCURS BECAUSE DRUG USE
OVER TIME CHANGES THE BRAIN IN WAYS THAT PERSIST LONG AFTER THE INDIVIDUAL
STOPS USING DRUGS. TREATMENT NEEDS TO ATTEND TO THOSE BRAIN CHANGES,
BOTH PHARMACOLOGICALLY AND BEHAVIORALLY."

Leshner noted
that the complexity of addiction is
compounded by a
chronic relapse rate
caused by stress
and exposure to
drug-associated
stimuli. "In the
past few years, we
have discovered
that when an individual is merely exposed to such
stimuli, the brain
reacts the same way it does when the
individual has taken drugs, which
shows that addiction is a brain disease
that has social and behavioral aspects
embedded into it.
"Like it or not, we need to acknowledge that when we are dealing with

Harold Strauss Named Chair of
Physiology and Biophysics
arold C. Strauss, MD, former Edward S.
Orgain Professor of Cardiology at Duke
University Medical Center and a specialist
in ion-channel function, has been named
chair of the Department of Physiology and
Biophysics in the University at Buffalo School
of Medicine and Biomedical Sciences.
Strauss held appointments in medicine and pharmacology at Duke, and for the past13 years served
as director of its multidisciplinary Specialized Center
of Research in Ischemic Hearl Disease/Congestive
Heart Failure. He brings to UBan extensive research
background in the electrophysiology of cardiac cells

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addicted individuals, we are dealing with
individuals in another brain state. lt was
very difficult for people to grasp this 10
years ago, but we have finally come to
understand that people are compelled to
use drugs because they are in a different
brain state, and treatment needs to
attend to those brain changes.
"The reason we have to care about
the nature of the illness, which in this
case is biobehavioral, is that it tells us
about the nature of the treatment we
have to use," he continued. "Treatments
need to attend to the biology, the behavior and the social context simultaneously
or they will not work as well. "
Leshner announced that the NIDA
has declared its next major nationwide
initiative to be improvement of treatment. Toward this goal, the institute is
developing a new ational Drug Treatment Clinical Trial Network to facilitate

and is principal investigator on three major federal
grants studying the structure and function of potassiumchannels in order to develop safer and more
effective antiarrhythmic drugs.
Anative of Canada, Strauss earned his medical
degree from McGill University in Montreal in 1964
and completed an internship and junior residency at
Montreal's Jewish General Hospital. From 1966 to
196B,he was a postdoctoral fellow in pharmacology
at Columbia University's College of Physicians and
Surgeons. He then completed a one-year residency
in medicine at Bronx Municipal Hospital Center,
Albert Einstein College of Medicine, and a two-year
cardiology residency at New York's Presbyterian
Hospital.
In recognition of two decades of involvement
with the American Heart Association, Strauss

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the dissemination of treatment information. "We are going to use science to
improve the quality of existing treatments and look for new treatments."
The project will involve a network of
interconnected sites around the country,
he explained. The hub of each site will be
a coordinating center, such as a university or hospital, and each coordinating ..
center will be attached to 10 or 15 local &lt;
community-based treatment programs "'
that will become partners in the research u
to be carried out. The research will involve testing scientifically developed "
treatments in real-life settings rather than
in the laboratory.
"People want a simple solution to
drug abuse and addiction , but we will
never have a handle on the problem until
the solutions are as complex as the truly
multifaceted problem that we are trying
to address," Leshner concluded. +

received its Award for Meritorious Achievement in 1996. He
has served on various committees and boards of the National
Heart, lung and Blood Institute
of the National Institutes of
Health. He isassociate editor of Circulation Research
and is on the editorial board of the Journal of
Cardiovascular Electrophysiology. As a researcher,
he has published more than 100 articles in peerreviewed journals and authored numerous review
articles and book chapters.
Amemberoft he New York Academy ofSciences
and a diplomate of the American Board of Internal
Medicine, he is affiliated with several additional
professional organizations. +
-LOIS

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AKER

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g
Sexual Identity Issues in aClinical Office Setting
to this is if your life or someone else's
life is in danger. Do you have any
attraction to members of one~ own gender and is part of the questions?" Right there an atmosphere
continuum of sexual expression. Many gay and lesbian youths of trust has been created and the message sent that the adolescent's rights
first become aware of and experience their sexuality during will be respected. A similar statement,
emphasizing confidentiality, can be
adolescence. Therefore, pediatricians who care for teen-agers need to made to adults.
How we ask the sexual history is
understand the unique medical and psychological issues facing homoimportant. Everyone develops his or
sexually oriented youths.
her own style with which they are
comfortable. The HEADSS model of
-from the American Academy of Pediatrics' Policy Statement on interviewing adolescents involves discussing Home, Education, Activities,
Homosexuality and Adolescence
Drugs, Sex and Suicide. What we don't
Most primary care specialties have a hear. We can foster this feeling by want to do is assume heterosexuality
similar policy statement concerning ho- having materials in the waiting room: by our questions. To a male, we don't
mosexuality. However, few physicians posters depicting same-sex couples want to ask, "Do you have a girlfriend? "
feel they have been adequately trained to alongside heterosexual couples; books In doing so, we implicitly communideal with issues of sexual identity. To and pamphlets that discuss issues of cate that it isn't possible he's gay and
this end, I presented a Grand Rounds at sexual orientation; or a rainbow sticker it's bad if he is.
Consider trying this phrase instead:
Children's Hospital ofBuffalo onjuly 24, on a window or wall (the rainbow is the
gay pride symbol). "Some of my male patients your age find
1998, titled "Caring for
These simple actions themselves attracted to men, some to
Your
Gay/Lesbian/
BY
are profound gestures women, and some to both. How is it for
Bisexual Patients and
FRANK
P .
of affirmation for youth you?" This question resonates with paFamilies." Colleagues
CARNEVALE.
MD
starved for images of tients on several levels. It affirms and
have since told me of
themselves and for normalizes their experience by stating
their success in using the
places they can turn to they are not alone. It presents their emergapproach I outlined at
ing sexual identity in nonthreatening
that time. This approach entails three for help. That's what they see.
What they hear are the statements true-to-life terms-that they "find themsteps: Safety, Support and "Referral"three simple, brief, inexpensive, yet we make and the questions we ask, selves attracted." (For most people, inteenormously powerful, interventions for both of which speak volumes. For grating their sexual identity into their
dealing with sexual identity issues in a example, if it's the first time I've met lives involves first noticing their feelings;
the teenager, I like to preface my en- it's a discovery process.) Finally, the quesclinical office setting.
tire interview with a statement about tion accepts all points on the Kinsey Scale
confidentiality: "Now that you're an by not assuming any identity from the
STEP 0 E: SAFET
This is the first step for an important adolescent, I will treat you differently outset. And with that we've taken Step
reason. It's the basis for creating an than the younger kids. I'll be asking One. We've created an atmosphere oftrust,
atmosphere that is conducive to open you questions about many aspects of which opens the door to communication.
discussion. Without a sense of safety, your life and it's important for you to
none of the remaining steps will take realize that what you tell me is confi- STEP Two: SuPPORT
place. Safety is simple to achieve. People dential. I won't talk about it with your What if the patient responds that he
perceive a sense of safety from their brothers, sisters or parents, unless or she has feelings of attraction tosenses-what they see and what they you want me to. The only exception ward the same sex?

Q,\IOSEXUALI TY IS TP-,:; PERSISTENT SEXuAL and emotional

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�. . . . •. . . • . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .

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This leads us to Step Two of our
three-step model: support. The
elements of this step are listening,
affirming, questioning further, correcting misinformation and assessing risk.
In other words, all the normal things
we would do with any other issue
or concern.
LI STEN !

G:

This may be the first time they are
talking about this. Let them tell you
where they are. It's a significant moment in a person's life when he or she
shares this with another.
A FFI R M !

G:

"Many people your age have this
experience; it's okay."
Q UESTION I NG FU RTHE R:

"Tell me more about that."
"What do you think?"
"What types of sexual experiences
have you had?"
"Have you been with men, women
or both?"
C O RR ECTING MI SINFO R MATION:

Patien t: "Well, I'm afraid this
means I'm gay."
Doctor: "What if you were?"
Patien t: "No way, then I'd never
have kids!"
Doctor: "Some gay men and lesbians
do have kids. Some choose not to."
Patien t: "But if I'm gay I'll get AIDS."
What a great chance to discuss STDs
and pregnancy prevention.
A SSESS !

G RI SK :

We can address STD/HIV risk, substance abuse, suicide and physical abuse;

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again, we can ask all the
questions we would normally ask as part of the
adolescent interview.
STEP THREE: "REFERRAL"

I put referral in quotes because by referral I mean
connecting the patient to
appropriate resources. Obviously, if appropriate, we
can refer to a therapist, a
psychiatrist or a substance abuse counselor. More commonly, "referral" involves providing pamphlets, booklets,
books and phone numbers of supportive organizations.
RESOURCES FOR PHYSICIANS' OFFICES
A supportive group of volunteers from
PFLAG (Parents Families and Friends
of Lesbians and Gays) provided the
Children's Hospital Grand Rounds audience with resource packets on this
subject.
The PFLAG team has sifted through
the current literature and distilled,
compiled and organized the information into a usable format. The packets
can be provided to patients ancl!or their
families if the family knows the person
is homosexual.
If you would be interested in receiving a copy of this packet for your office,
simply mail a $3 check (to defray postage and handling costs) to PFLAG,
Attention: Resource Folder, P.O. Box
861, Buffalo, Y 14225. +

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recently completed his pediatric
residency at Children's Hospital
of Buffalo and, in]anuary 1999,
joined the University at Buffalo's
Student Health Center.
Dr. Carnevale wishes to thank
the following individuals and organizations for their support and
their roles in the Grand Rounds
presentation: Elizabeth B.
Conant, PhD, Camille Cox and
Curt Gregg,from PFLAG; Mary
Alice Boyd, MSW, from the Gay
and Lesbian Youth Services
(GLYS) of Buffalo; and the teens
from GLYS who sat on a panel
for the presentation.
He would also like to thank
Gerald Daigler, MD, from
Children's Hospital of Buffalo;
and Ross Hewitt, MD, who assisted in obtaining funds from
Abbott Laboratories in support
of producing the resource folder.

0

�The Evolving Ethics of Medicine
JEROME KASSIRER , MD ' 57 , KEYNOTE SPEAKER FOR
INSTITUTE OF HUMAN RELAT IONS AWARDS

HE \1A. XFv1 "0. 'CE A BUFFALONIAJ'.., always a Buffalonian"
was illustrated by the celebration surrounding the return of
Buffalo native jerome P. Kassirer, MD, editor-in-chief of the New

England]oumal of Medicine, who was in town October 26, 1998,
to receive the Institute of Human Relations Award from the American
jewish Committee of Western New York (AJC-WNY) . Kassirer, who
earned his medical degree from the then- University ofBuffalo in 195 7,
was honored for his promotion of medical
professionalism, ethical scientific conduct,
patient involvement in decision making and
reliable approaches to assessment of quality
health care. The AJC-WNY, in presenting Kassirer with the award,
acknowledged his numerous editorials on these topics, as well as
others on professionalism, appropriate use of firearms, the abuses of
managed care, and political intrusions into medical decisions.
In a keynote address, titled "The
Evolving Ethics of Medicine," Kassirer
lauded the AJC for battling intolerance
for nearly a century and cited the
murder of Dr. Barnett Slepian, Buffalo
obstetrician/gynecologist and abortionist, as an example of how much farther
the world has to go in order to truly be
"united as one human race. "

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Before an audience of more than
200, Kassirer then discussed a number
of current controversies in the medical
field and outlined their ethical implications. "This is the most tumultuous
time in the history of medicine. Technology and scientific advances in providing medical care have overtaken
society's willingness to pay for them.

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magna cum laude
from the University of Buffalo School of Medicine in 1957, Jerome P.
Kassirer trained in internal medicine at Buffalo General Hospital and in
nephrology at the New England Medical Center in Boston.
He joined the faculty of Tufts University School of Medicine in 1961 ,
was named professor of medicine in 197 4 and was the Sora Murray
Jordon Professor of Medicine from 1987 to 1991 . From 1971 to 1991 he
was associate physician-in-chief of the New England Medical Center and

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Health-care reforms occur minute by
minute. This is not the same field that I
entered 40 years ago, but physicians can
still influence the course of medicine
and maintain quality," he stated.
Kassirer is concerned with a marketdriven health-care system in which
expansive health maintenance organizations (HMOs), powerful investorowned conglomerates and armies of
health-care lawyers and consultants vie
for available monetary resources. "We
used to have a simpler one-patient and
one-doctor system, but now the
purchasing power of employers, and the
HMO practice of treating populations
rather than individuals, drives the
industry. Physicians need to take
control and get back to the practice of
medicine," he emphasized.
Currently, physicians are working
longer hours and seeing more patients
per hour to maintain their incomes, he
contended. More and more time is spent
processing paperwork, and stress is
rampant. As HMOs become dominant
in a community, physicians must
join them in order to maintain their
offices and keep seeing patients.
"Capitated care has tempted some
doctors to under-test and under-treat
their patients and avoid the patients
who are seriously ill. The industry today
pits the ethical needs of patients against
physician income and job security.
Physicians can be torn between their
patients and their families ," he said.

vice choir of the Deportment of Medicine at Tufts.ln 1991 , he become the
38th editor-in-chief of the New England Journal of Medicine.
Throughout his career, Kossirer has published numerous original
research and clinical studies, textbook chapters and books on nephrology
(acid-bose equilibrium, in particular), medical decision making and the
diagnostic process. He was o founder and coeditor of Nephrology Forum
in the journal Kidney International and of Clinical Problem Solving in
Hospital Practice until1991 .

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Kassirer was elected to Alpha Omega Alpha (AOA) as astudent and was
named the AOA Distinguished Clinical Teacher of the Year in 1989. He was
named Distinguished Alumnus of 1991 by UB's School of Medicine and
Biomedical Sciences and received the Distinguished Faculty Award from
Tufts University School of Medicine. He has honorary degrees from the
University of Massachusetts in Worcester, Thomas Jefferson University in
Philadelphia, the SUNY Health Sciences Center in Syracuse, l'Universite
Rene Descartes in Paris, Tufts University and the Medical College of Ohio.

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Kassirer served on the American College of Physicians' board of
governors and board of regents and in 1997 received the college's John
Phillips Award for his contributions to clinical medicine. He is past chair of
the National library of Medicine's Board of Scientific Counselors and past
chair of the American Board of Internal Medicine; he is also a member of
the Association of American Physicians and the Institute of Medicine of the
National Academy of Sciences.

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�While admitting that his talk might
be interpreted as painting a bleak
future for the field, Kassirer counIn Kassirer's view, the greatest threat
tered: "We should encourage our
to the medical field is loss of integrity,
children and our grandchildren to folwhich can be realized when physicians
low in our footsteps and enter the
under-treat their patients and decide
medical field. After all, we are not
that "it's for the best"; or, worse, use the
selling fake jewelry, we are not makHMO to justify suboptimal care.
ing weapons of mass
"We have to rememdestruction.
ber that the fee-for" THIS IS THE MOST TUMULTUOUS TIME IN THE HISTORY OF
We are privileged
service method was not
MEDICINE . TECHNOLOGY AND SCIENTIFIC ADVANCES IN PROVIDto help people and
perfect. The demands
make a decent living
of HMOs for prevenING MEDICAL CARE HAVE OVERTAKEN SOCIETY'S WILLINGNESS TO
while we help them. "
tive and cohesive care
PAY FOR THEM . HEALTH-CARE REFORMS OCCUR MINUTE BY
Crediting UB with
have improved mediMINUTE. THIS IS NOT THE SAME FIELD THAT I ENTERED 40 YEARS
giving him a superb
cine. Managed care has
medical education as
AGO , BUT PHYSICIANS CAN STILL INFLUENCE THE COURSE OF
also forced us to pay
well
as teaching him
more attention to preMEDICINE AND MAINTAIN QUALITY ."
how to write, Kassirer
ventive medicine, to the
closed by strongly enmanagement of chronic
diseases, to the quality of care and the cost policies in their region and to deal with dorsing the concept of medical schools
of care. I believe that we would not have ethical lapses when they arise. "We need teaching medical ethics as a means of
made so much progress in these areas to maintain the public trust or we have helping future physicians learn how to
without the prodding of managed care. " nothing. We must remain patient advo- better provide quality care in what is
Kassirer outlined ways physicians can cates and fight for their rights and reject sure to be a challenging health-care
preserve their integrity, suggesting that attempts to limit care," he emphasized. environment. +

CONTINUED

OTHER

FROM

1998

PAGE

RECIPIE

31

the first thing they should do is admit
that money isn't everything. Also, they
should remain true to themselves, and
not bend to pressure from outside
sources, including pharmaceutical companies and manufacturers of medical
devices. Instead, local physicians should
stand together to help create medical

TS OF THE INSTITUTE OF HUMAN RELATIONS AWARD OF THE AMERICAN

jEWISH Cow~11TTEE OF WESTERN NE\\ YoRK:

I. PUTNAM , MD ,

EVAN CALKINS , MD ,

LINDA C. DUFFY , PHD ,

FREDERICK E .

THEODORE

professor emeritus of medicine and
family medicine at the University at
Buffalo School of Medicine and
Biomedical Sciences; consultant in
geriatrics programs, Health Care Plan;
and partner, Promedicus Group, was
honored for "his long and devoted
leadership in medical education and
outstanding contributions in the fields
of geriatrics/gerontology, rheumatology and general medicine."

associate professor of pediatrics at
the University at Buffalo School of
Medicine and Biomedical Sciences and
executive director of the Women and
Children's Health Research
Foundation, was honored "for
designing and developing the
Doctor's Pediatric Immunization
Program, and expandable Children's
Hospital of Buffalo's Expert Software
System that monitors and tracks
childhood vaccinations."

MUNSCHAUER Ill , MD ,

associate professor of clinical
pediatrics at the University at Buffalo
School of Medicine and Biomedical
Sciences, director of Ambulatory
Services and chief of the Division of
General Pediatrics, Children's Hospital
of Buffalo, was honored "for his
tireless effort in the establishment of
outreach pediatric centers that
provide quality health care to needy
children in their own communities."

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associate professor of clinical
neurology and internal medicine at
the University at Buffalo School of
Medicine and Biomedical Sciences,
associate head of the Department of
Neurology and head of the Vascular
Disease Prevention Research Center,
Buffalo General Health Systems,
was honored "for his groundbreaking
research in multiple sclerosis and the
development of a simple selfexamination that can detect atrial
fibrillation, a major risk factor
for stroke."

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�BY

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LINDA

CORDER .

PHD ,

CFRE

The Gift to Know Them Deeply
bers, each of whom lighted a candle before
I trouped over, with
speaking.
the Class of 2002 and a few assorted others,
Some recited poetry-"Death be not proud ... "
to Harriman Hall for a memorial service.
I could not stop for death, Death kindly
"Because
That experience influenced me to change
stopped for me ... "-old favorites that have
focus, however briefly, from thoughts of
helped many of us to accept the death of
facilitating philanthropy to another type of
someone close. Several gave examples of what
gift, that of a person's body, given to facilitate the
they learned-about cancer through a tumor
education of future physicians.
in
a woman's lung; from finding an implanted
I was struck, initially, with the diversity of
pacemaker
that had not been "enough" to
our newest class-roughly half women and half
keep
the
heart
of a man, younger than his dad,
men, a rainbow of skin tones , a rich texture of
beating; viewing in awe the slack, translucent
various ethnic backgrounds and, as I was to
skin of a woman who reminded
hear, a broad representation of
one student of his granny. Anpersonal religious beliefs. Our
The service was simple; those memorialized were known
other student read a letter from a
beautiful children of yesterday,
person whose body became "a
our healers and health-care givers
not by name but by what they had taught.
teacher" for a previous class. One
of tomorrow ...
entreated,
"Don't think of this as
The service was simple; those
my deathbed; rather, think of it as a bed of life," followed by
memorialized were known not by name but by what they
what each organ might mean if donated, what nerves and other
had taught. Though unknown while living, they were rectissues might teach to those with the patience to learn. Several
ognized as true friends in their generosity of spirit and their
talked about the relationship they experienced with their
lasting impact on the lives of the students who had shared
cadaver-what
they learned always outweighing the frustra"the privilege to cut them and know them deeply ..,
of
not
knowing
details that will forever remain hidden.
tions
One of the faculty members told about his mother's
end,
each
speaker
lit the candles of those seated nearby,
At
the
decision to leave her body to the medical school where he had
bathed
in candlelight. Each of us left the
until
the
room
was
received his education. This past Thanksgiving was his
service with a single rose, symbol of memory and hope ...
family's first without the smile of his mom across their table.
So it was that on one of the year's dark, gloomy days, I
He recalled an earlier Thanksgiving when she had first
paused in my daily routines to light candles, to celebrate
discussed her decision, and the experiences that had led to
and remember generous folks I did not know. With those
her choice. As an educator, this was one final way she could
students,
I was thankful for mute teachers who had made
influence and teach another group of young people.
such
a
contribution
to the understanding of human strength
We learned some facts from the chair of the Department
and
frailty,
the
diagnosis
of disease, the alleviation of pain
of Anatomy and Cell Biology. Our school is one of very few
and
suffering.
Standing
with
those young, idealistic physiin the world with a gross anatomy lab populated entirely by
cians of the future, I realized that it is for experiences like
those who made a conscious choice of that place as their final
these that I chose both my profession and UB's School of
destination. We are extremely fortunate that over 7,000
Medicine and Biomedical Sciences. The focus of that memopeople now living in Western New York have made arrangerial service was, indeed, different from my daily routines.
ments to join that distinguished company in the future. Our
However,
the purpose of "anatomical gift" donors is very
students are privileged, knowing that those people from
much
the
same-facilitating
the education of future physiwhom they learn held medical education and research in the
in
the
best
way
they
know.
cians
highest esteem. Our school is fortunate to have students who
show such reverence and respect for the human spirit and the
Linda). Corder, PhD, CFRE, is an associate dean in the School of Medici ne and
individual bodies that were animated by that spirit.
Biomedical Sciences at the Uni versity at Buffalo. She can be contacted by phone
As an onlooker, I gained a sense of their journey of
at (71 6) 829-2773, toll free at J-877-826-3246; by fax at (716) 829-3395; or
by E- mail al ljcorder@acsu.buffalo.edu.
discovery through reflections from at least 15 class mem -

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�1998 Distinguished Medical Alumnus Named
JOSEPH BELL ANT I, MD '58

MD, director of Georgetown University's
International Center for Interdisciplinary Studies oflmmunology,
received the Distinguished Medical Alumnus Award from the
University at Buffalo School of Medicine and Biomedical Sciences at a dinner
held in his honor on September 12,
1998, at the Buffalo Club.
Bellanti, an expert in developmental immunology, earned a bachelor's
degree from UB in 1954 and a medical degree in 1958. Before beginning
his career at Georgetown, he interned at Millard Fillmore Hospital,
completed a pediatric residency at
Children's Hospital of Buffalo , was a
ationalinstitutes of Health trainee
in immunology and spent two years
as a research virologist at the Walter

Reed Army Institute of Research in
Washington, DC.
Bellanti joined the Georgetown faculty in 1963 as an assistant professor
of pediatrics and microbiology, and
by 1970 had attained the rank of professor in both fields. He also is director of the Division of Immunology and
Virology in the Department of Laboratory Medicine at Georgetown University Hospital.
Adopting a multidisciplinary
approach to medical research before
it was fashionable, Bellanti spearheaded development in 1975 of the
International Center for Interdisciplinary Studies of Immunology at
Georgetown . The center brought
together basic and clinical researchers, allied health professionals,
statisticians and health educators.

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AKER

Past presidents of UB's Medical Alumni Associationgather to honor Dr. Bellonti.

John R.Wright, MD, dean, UB School of Medicine and Biomedical
Sciences; Mrs. Jacqueline Bellonti; Joseph A. Bellanti, MD, Closs of 1958 and this
year's recipient of the Distinguished Medical Alumnus Award; Elizabeth l. Maher, MD,
president, Medical Alumni Association.

®

He has been director of the center
since its inception.
Bellanti has held many leadership
positions in professional societies, including director, and later cochair, of
the American Board of Allergy and
Immunology; president of the Society
for Pediatric Research and of the American College of Allergy and Immunology; member of the board of directors of
the National Coalition for Disease
Prevention and Environmental Health;
and member of the board of regents of
the American College of Allergists.
An author of more than 200 scientific articles and abstracts and editor
of the textbook Immunology, Bellanti
served for 10 years as editor-in-chief
of Pediatric Research. He also is past
editor of Annals of Allergy. +

Franklin Zeplowitz, MD '58; Paul H. Wierzbieniec, MD '74;
Robert E. Reisman, MD '56.

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�Let the Adventure Begin!
· - STUDENTS BID A HALE- AND- HARDY
BON VOYAGE ON SEPTEMBER 12 , 1998 , AS THEY PREPARE TO
EMBARK ON A WHIRLPOOL JET TOUR AT NIAGARA-ON -THE- LAKE ,
ONTARIO . THE OUTING TOOK THEM THROUGH THE WORLD·
FAMOUS RAPIDS AND STONE-WALLED CANYONS AT NIAGARA

w{e a mistake. But not from the inside .
The roof look." funny, odd, strange, a\'\0

\\'hich means thev can look at more than the bael\ of the
D 1e wav we see it, whv build a strai~ht roof when you
front seat. ~ l uch more, in fact.
can build a perfeetlv ~ood crooked one''
Because the Land Rover DiseO\·erv has more windows
It's somethin~ up w se,·en passenl\ers in the Land
than anv other -lx-1.
Rover DisCO\'Crv will rrulv appreciate.
\\'ith the ele,·ated roof and stadiumlil;e sea tin~. • • \\'hv nm take one out for a test drive·~
~'!'!!!!""~ ,\nd instead of just looking into it , look out of it.
passengers in the rear ha\'C ample headroom .
DISCOVERY

Land Rover Amherst
A NOIUHTOWN AIJTOMOTM COMPANY

3560 Sheridan Drive
Amherst, New York 14226 • (716) 831-3100
http//www.northtownauto.com

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-MARK YOUR CALENDARS!

t's not too early to plan for the 1999 Spring Saturday, May l. For more information, call the
Clinical Day and Reunion Weekend. Medical Alumni Association at (716) 829-2778.
A cocktail reception will be held on Friday,
The reunion classes are of 1939, 1949, 1954, 1959,
April 30, 1999. The 62nd Spring Clinical 1964,1969, 1974,1979,1984, 1989and 1994. Here's
Day and Reunion Dinners will be on what your reunion chair has to say to you ...

ELIZABETH OLMSTED

CLASS O F 1 939

CLASS OF 1954

CLASS O F 1969

Elizabeth Olmsted Ross
Mayday! Mayday! Mayday! Last
chance to celebrate your 60th
May Day '99.

Nicholas C. Carosella,
Edward A. Rayhill
45 Years! (an you believe it?
Come join your friends and classmates in celebration.

James White, Hanley M. Horwitz,
Gerald D. Stinziano
Don't miss our 30th! It should
be fun to see how we, the school
and Buffalo have changed in 30
years. Let's get reacquainted and
renew old friendships.

Ross
CLASS OF 1949

Richard L Schwartz,
Robert (. Harvey
It has been 50 years since graduation. Don't miss this chance to
get together and celebrate.
CLASS OF 1959

William J. Mongan
Please come to our 40th
reunion.

Roam L HARVEY
CLAS S OF 1 974

CLASS O F 1 964

J. Frederick Painton

Bruce F. Middendorf
Looking forward to seeing all of
you at our 25th class reunion.

Our 35th reunion is imminent.
Return to Buffalo to renew old
friendships and pleasant
memories.
J. fREDEIIU PAINTON

®

Buffalo

BRUCE

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--··,

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4

EDWARD M . TRACY '43
CLASS

E.

SHIELDS

1

5

0

s

and
his wife , Elaine, write: We

OF 1984

March 1998 and bought our
daughter's home. Life in
Pensacola is much more laid
back. The 1998 summer was
unbearable, so we are planning
to return to our chalet near
Ellicottville, Y, next summer.
Ed is involved with a barbershop chorus and quartet. We
miss our friends. Our E-mail
address is Eohohensee@aol.com.

EDWARD

CLASS

1

OF 1 989

Barbara J. Bambach,
Denise M. Callari
Ten years already! Come
share memories, laughs and ac·
complishments!

9

WILLIAM

6
E .

0

ABRAMSON

s

text on radiology for medical
students.

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s

THOMAS A. LOMBARDO JR . '73

has been elected to the board of
trustees at the ichols School of
Buffalo for a three-year term.
Lombardo, an orthopaedic surgeon and a ichols parent, is director of CGF Health System,
secretary of the YS Society of
Orthopaedic Surgeons, immediate
past-president of the medical staff
and current chair of the Department of Orthopaedic Surgery at
Millard Fillmore Health System.
Lombardo and his wife, Donna,
reside in East Aurora, NY, and are
the parents of four daughters.

' 60

writes: l have been elected a Life
Fellow of the American Psychiatric Association. l'm working
part time in a solo private practice of psychiatry and addiction
medicine at Sheppard Pratt Hospital in Towson, MD. I'm working less, traveling more and

BAMIACH

recently had the second edition of
his text Clinical Radiology: The
Essentials
published
by
Lippincott Williams and
Wilkins. This is an introductory

RICHARD H . DAFFNER '67

HOHENSEE ' 54

moved to Pensacola, FL , in

David F. pfalzer
Please come bock to reunite with
Herb and the rest of the
Class of '84.

J.

9

Frank T. Schreck
Sex, lies and videotape ...
we'll capture it all. Show up!

CLASS

Bmm

is prac-

ticing internal medicine in
Charleston , SC, and lives on
Seabrook Island. He also teaches
diabetic care in Beijing, the
People's Republic of China.

OF 1979

Peter E. Shields
Come bock for our 20th reunion
and reminisce with your old
friends.
PETER

s

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RICHARD 5 . LEE '74 writes:
have been appointed western
regional medical director for the
Sleep etwork, Inc., and Northern evada Sleep Disorders Cen-

ter. In April 1998, I became a
diplomate of the American Board
of Sleep Medicine.

enjoying both.
HENRY M . BARTKOWSKI

retired for
the third time on October 14,
1998. He sold his practice of 30
years to Memorial Hospital of
Salem County, FL. He travels to
Fort Hood , TX , to see his
grandkids, Garrett (6) and
Skylar (4). He also sees all the
Washington Redskin games because his daughter, Stephanie,

JOHN J . LAMAR '63
CLASS

OF 1 994

Donald M. Slate
While following our dreams, we
all have disbursed but there will
be a party next year an May
first! I cannot believe it's been
five years, so come bock and
we'll share stories, laughs and a
couple of beers.

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'76 ,

a

pediatric neurosurgeon, was recently appointed chief of pediatric
neurosurgery at Henry Ford Hospital in Detroit, MI, and William
Beaumont Hospital in Royal Oak,
MI. His special areas of interest are
brainandspinalcord tumors,spine
instrumentation, and brain and
spinal cord injury. Bartkowski's
research work involves cerebral
ischemia in children.

®

�l ll ·························································································
HERBERT B. NEWTON '84 writes:
My son, Alex (5), has started

rics (Amherst, NY), effective

but I love it. I came

August 1998. I continue to work

bus, OH, because of my hus-

ogy, was made a fellow of the

kindergarten. He is heavily into

as a part-time pediatrician at

band, Emeka. I have three ch il-

American College of Radiology

soccer and swim lessons. Ashley

the Erie County Health Depart-

dren: Chiedu ( 4), Chidi (2),

at its annual meeting in Septem-

(21J2) is enjoying preschool.

ment. My husband , RICHARD E.

and Chinenye (9 months). I

ber 1998. Fellowships in the
college are

On the academic front, I have
b e e n

GERGELIS '84, is an assistant
professor in the University at

think I keep myself busy. I

named

Buffalo's Department of Psy-

LIVERPOOL '90 . He is well and

ANGELO M. DELBALSO '78, chair
of UB's Department of Radiol-

awarded

to

members for
scientific or
clinical

re-

search in the field
of radiology or

Classnotes can also be

significant contributions to its literature. Criteria
for selection also

one

s

significant

submitted via E-mail to:
bpnotes@pub.buffalo.edu

include performance of outstanding service as a teacher of
radiology, service to organized
medicine and outstanding reputation among colleagues and the
local community as a result of
long-term superior service.

BENSON ZOGHLIN '84 writes:
The whirlwind of activity grows
ever stronger. In addition to a
busy group practice in family
medicine, lam president-elect of
the Lakeside Hospital medical staff
and chief of family medicine at
Lakeside. Our group precepts
third-year medical students from
the University of Rochester and 1
precept at Highland Hospital's
Family Medicine Residency Program. I am on the board of directors of the Lakeside Foundation.
Mindy is busy with her law practice, and jacob (9) and Rachel
(13) have their own hectic pace.

has a daughter, Asha, who is
my godchild.

the top
five neu-

involved in fore nsic work. We

rologists

in Central

have three children: Kristyn
(11), Kimberly (8), and

Ohio by an

Scott(4). We have remained

indepen-

loyal to Western

dent survey

reside in Williamsville. We hope

ew York and

sponsored
and pub-

to see you all at our respective
reunions, and can't believe it's

lished by the
Columbus

been 15 years!
JOEL K. SHUGAR '85: See letter

in an exchange program as a
member of the International
Medical Relief organization of
Western

ew York. The pro-

gram is designed to bring
physicians from Third World
countries to Buffalo for additional training and to send local
physicians overseas to work in
countries where sufficient

dependent practice associations.

molecular biology at the University of Texas at San Antonio.

1

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Mindy and Icontinueourstudy in

ciation with Sheridan Pediat-

easy being on call all the time,

o

BURNETTE

THOMAS

'94

proudly announce the birth of
their daughter, Kristen Killian
Burnette.
Kristen was
born on July

ll, 1998, and
weighed

6 lbs., 9 1/ 2 oz.
She was 19 3/ 4
inches
in
very

well.
MARC
ROMANOWSKI
'93
AND CINDY ROMANOWSKI '94
are proud to announce that they

Isshin Ryu karate.

l

CAROL ANN KILLIAN AND

cently took a position in

went into solo practice in OBI
Gyn one year ago. lt is not

a

I've gotten married. My wife's

doing
THOMAS BOYER '89, PHD, re-

NGOZI OSUAGWU '90 writes:

f

cal Group.

length . All are

experience with managed-care
organizations and physician in-

tice of general and vascular
surgery with the Buffalo Medi-

pecting our first child in April.

with officials in Tanzania.

credentialing at Independent
Health. She brings 12 years of

first child. I continue my prac-

RIYAZ HASSANALI '86 is involved

has recently returned to her na-

of physician management and

the birth of Olivea Marie, our

name is Sherry, and we are ex-

on page 40.

tive Buffalo, NY, with her appointment as assistant director

MICHAELA . VASQUEZ '90 writes:
Melissa and I have celebrated

ATUL KUMAR GUPTA '91 writes:

health-care options are not available. Currently, he is working

ROCHELLEJ . PLESKOW '85, MS ,

f

keep in touch with STEVEN

chiatry, based at the Erie County
Medical Center, and is actively

Monthly magazine. I was also
named to the Central ervous
System Panel of the ational
Comprehensive Cancer etwork. Also, recently I was informed that I will be listed in the
1998-99 issue of The Best Doctors in America. I remain associate professor of neurology and
director of the Division of
euro-Oncology at the Ohio
State University Hospitals and
james Cancer Hospital.

B

Colum-

of

ELAINE M. SCHAAF '85 writes:
I'd like to announce my asso-

®

to

p

y

s

c

a

n

had a son, Marcus ] r., born on
August 28, 1998. They reside
inWilliamsville, Y, where Marc
is an orthopedic surgeon and
Cindy is practicing rehabilitation medicine.

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..............•
._-·._
•

RESIDENTS
R AYMOND 0 .

S C H ULTZ '95 ,

a

plastic surgeon who specializes
in problems of the hand and wrist
and in reconstructive surgery, has
joined the Center for Plastic
Surgery. His
main office will
beatthecenter's
new Orchard
Park, NY, facility at 3725
orth Buffalo Road. Schultz completed a general surgery residency
at UB from 1991 to 1995. Currently, he is a clinical assistant
professor at UB, where he is actively involved in research, having recently made presentations
on facial nerve injuries and compression neuropathies.

IN MEMORIAM
an internationally known ophthalmologist and eye surgeon who

ME Y E R H . R IW C H UN '27 ,

of surgery and chair of ophthalmology at the UB medical school ,
died at age 95 on October 25,

ety, the Maimonides Medical Society and the former Buffalo Eye
and Ear Hospital. Active in the

1998, in Buffalo. Riwchun, who
maintained a private practice in
Buffalo from 1929 to 1985 ,

Sight Conservation Society, he
was a member of the advisory
board of the Buffalo Eye Bank. In
1979, he and his wife , Ann , were

headed the departments of ophthalmology at Buffalo General
Hospital and Children's Hospital , respectively, in the 1960s. He
was attending ophthalmologist
at the former Deaconess Hospital
and ophthalmologist-in-chief at
the former Rosa Coplon Home.
He was a lieutenant colonel in

jointly named Outstanding Citizens of the Year by the Buffalo
News for their work with the
blind.
D ONALD L. E HRENREICH ' 5 3,

a

clinical professor of neurology
at UB School of Medicine and
Biomedical Sciences and a neurologist with the Buffalo Medical Group , died ovember 18,
1998 , in Buffalo General

the Army Medical Corps during
World War ll, serving as chief of
eye service at Walter Reed Hospital in Washington , DC. Highly
regarded as a teacher in the UB
medical school , Riwchun was a

Hospital 's Hospice Unit.
Ehrenreich , who was 70, suffered from cardiac and other
medical problems. He earned a

diplomate of the American Board
of Ophthalmology and a fellow
of the American College of Sur-

bachelor's degree from UB in
1949 and a medical degree from
the UB medical school in 1953.
He became an instructor in the

geons and the American Academy
of Ophthalmology and Otolaryngology. He served as president of
the Buffalo Ophthalmology Soci-

Department of Neurology in the

I

medical school in 1961. Since
1983, he had served as a clinical
professor in that department. He
was acting head of the neurology department at Buffalo General Hospital for six years in the
1980s, served as president of the
hospital's medical staff in 1986
and was a member of the board
of trustees for six years. In 1978
he joined the Buffalo Medical
Group and later served as chair
of its board of directors. Survivors include his wife, Rivona H.;
a son , Mark D. of Kenmore; a
daughter, Beth E. Lichtenberg
of Chicago; a brother, Arthur, of
Phoenix; and a sister, Margery
Rabow of Sarasota , FL.
O SC AR

R .

OBE RKIRC H ER

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died August 6, 1998. A classmate writes: Oscar, a pediatric
nephrologist, retired from the
Geisinger Medical Center at
Penn State University two years
ago. Friends, family and patients
will miss this wonderful man.

had served as a clinical professor

Richard H. Webber, 74, Professor Emeritus of Anatomy, Dies
Author of numerous scientific papers, Webber received grants from the National
Institutes of Health while at U8to study involuntary nerve pathways to blood vessek
in the leg. His major research interests involved the autonomic nervous system and,
in later years, neuropeptide changes in gingiva. He retired from UB in 1990.
Webber was a member of Phi Rho, a professional and neurological
society; the American Association of Anatomists; the Cajal Club, an anatomy
organization; Sigma Xi and the American Association of Dental Schools. He
was a Fellow of the Human Biology Council.
Survivors include his wife, Donna Marie; six daughters, Michaeline
Reining and Donna Goss of Grand Island, Margaret Hooper of Ogdensburg,
Patricia Majtyka of North Tonawanda, Anne Smith of Pullman, Washington,
and Kimberly Marshall of Buffalo; a son, Thomas, of Rochester; and eight
grandchildren.

ichard H. Webber, professor emeritus of anatomy in the UB School
of Medicine and Biomedical Sciences, died November 23, 1998,
in Millard Fillmore Suburban Hospital in Amherst, New York. He
was 74.
Webber was attending Cornell University in 1943 when he
joined the Navy. Following his discharge, he completed his
bachelor's degree at St. Benedict's College in Atchison, Kansas,
then earned his master'sin zoology at the University of Notre Dame in 1949
and a doctorate in anatomy from St. louis University in 1954. From 1954
to 19 59 he was an assistant professor of anatomy at the Creighton
University Medical School, where he was principal investigator for several
research grants from the U.S. Public Health Service. Prior to coming to UB
in 1961 , he was an associate professor at Temple University.

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writes: Well ,
I've been meaning to do this for
years, so better late than never.
joel K. Shugar '85, checking in
for the first time since graduation. I've got a lot to report.
After my internship in
internal medicine at Millard
Fillmore, of which I have
especially fond memories, I
completed my residency in
ophthalmology in Gainesville,
at the University of Florida.
While in Gainesville, I met my
soul mate, Michelle, whom I
relentlessly pursued until she
agreed to marry me. After seeing a lot of trauma during a
rotation in jacksonville, as well
as living through the Gainesville
murders ordeal, we decided to
settle in a rural location and set
up practice in Perry, Florida,
in 1991. In retrospect, it was
the best financial decision we
could have made, since rural
areas are relatively sheltered
from managed care and physician demand exceeds supply.
We started as a small "Mom
J O EL S HU GAR ' 85 ,

and Pop, " but the
practice experienced
growth beyond our
wildest expectations.
Because of the critical
physician shortage in
the area, we offered
laboratory services and
family care in addition to ophthalmology. Havingspent5 ,000
hours moonlighting as an ER
physician to pay off my loans
in addition to my internal medicine training, I was comfortable
to offer those services to fulfill
the community need. However
the ophthalmology practice
grew explosively, and it became
obvious the days of the solo practitioner and "Mom and Pop"
operations were numbered.
What also became obvious is
that physicians need to take back
more control of health care and
that I either needed to hire someone in a suit, or pretty soon I
would be working for nonphysician-directed corporate
medicine. So I recruited the chief
operating and chief financial
officer from a 500-bed hospitalnursing home facility to be the

COO/CFO of our
practice.
Together we are
evolving a physiciandirected healthcare system. The
practice was folded
into Nature Coast
Health Care , a multi-specialty
group practice that currently
has 80 employees. We have a
couple who are respectively
boarded in internal medicine and
pediatrics as well as a nurse practitioner specializing in women's
health. We are recruiting a family practitioner to complete the
primary care group in our Perry
location. We are also in the process of establishing several satellite locations and would welcome applications from any colleagues from UB.
In addition to the Family Care
Center, we just completed
construction of ature Coast
Regional Surgery Center/Nature
Coast Eye Care Institute, which
won Medicare approval in
October and will undergo
JCAHO accreditation in
January. We anticipate ENT,

general surgery and gastroenterology joining us in the near
future as well.
In addition to being very busy
surgically, our practice has
produced significant research,
including the first reported use
ofTPA for central retinal artery
occlusion.! have been fortunate
enough to be selected as a
peer reviewer for Archives of
Ophthalmology and thejoumal
of Cataract and Refractive
Surgery, and have served as a
faculty member of the American College of Eye Surgeons.
Other than work, Michelle
and I have taken the time to get
and stay in very good shape. We
lift weights and do yoga together;
I run three miles a couple times
a week as well. o children in
the picture yet, but the negotiations are going on, so stay tuned!
Well I promise it won't be
another l3 years before you hear
from me again! For colleagues
who would like to reach me,
my office phone number is
( 850) 584-2778 , and my
E-mail
address
is
eyeworks@perry.gulfnet.com.

Louis Bakay, 81, Retired Professor, Chair of Neurosurgery
OUIS BAKAY, a brain surgeon, professor emeritus of the

University at
Buffalo School of Medicine and Biomedical Sciences, and retired chair
of neurosurgery, died on September 10, 199B, in his Buffalo home.
Anative of Hungary, Bakay received his medical training at the
University of Budapest. He came to the United States in 1948 as a
Harvard Research Fellow at the Massachusetts General Hospital,
where he remained until 1961 . He was appointed that year as
professor and chair of neurosurgery at the UB medical school, where he
served for 23 years.
Bakay focused his research on the blood-brain barrier and aspects of cerebral
edema. He was the author of several books on those topics, as well as chapters in
14 surgical handbooks and more than 100 scientific papers. Several of his books
were translated and published in Spanish, Russian and Japanese. After his

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retirement in 1984, he wrote amemoir, Gallery of
Ghosts, followed by Gastronomic Exotica.
Bakay received the Distinguished Alumni
Award in 1989 from the Massachusetts General
Hospital, an honor given to only five graduates
of the hospital's neurosurgical program who
had made significant contributions to neurosurgery. He was cited for his pioneering work
on brain injuries. In 1997, the Louis Bakay
Neuroscience Laboratory was dedicated at Buffalo General Hospital and a
fellowship in neurosurgery was established in his name.
He is survived by his wife, Nancy; daughter, Stephanie of Boston; son,
Nicholas of Los Angeles; and sister, Margitt de Balas-Piry of Budapest.

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Our case mix is consistent with the Northeast and national subacute region. Our
average statistics are: length of stay - 25 days; age- 78; admission F1M score 72.5; discharge F1M score- 97.6; F1M change- 25.1 points; length of stay
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                    <text>�BUFFALO PHYSICIAN

Volume 34, Number 1
ASSOCIATE VICE
PRES IDENT FOR
UNIVERSITY SERVICES

Dr. Carole Smith Petro
DIRECTOR OF
PUBLICATIONS

Dear Alumni and Friends,
lr

HAS BEET\1 "THAT TIME OF YEAR" -\GAIN -

Spring Clinical Day and five-year

reunions for alumni; orientation programs for incoming chief residents; achievement awards ceremonies; the pre-finals "follies" presentation by first- and second-

Kathryn A. Sawner

year students; graduation dinners and, of course, graduation itself. During it all, I

ED ITOR

endeavored to perfect the art of being in more than one place at one time-with less-

Stephanie A. Unger
ART DIRECTOR/DESIGNER

Alan j. Kegler
PRODUCTION

than-complete success, but it was fun trying! The good news is that all events were
highly successful.
The 60th class reunion was organized by Dr. Elizabeth Olmsted Ross, who, with

Cindy Todd

the able assistance of Mary Glenn from our development office, com-

STATE UNIVERSITY OF
NEW Y ORK AT BUFFALO
SCHOOL OF MEDICINE
AND BIOMED ICAL
SCIENCES

posed a "class book" complete with photographs and an update on

Dr. john Wright, Dean

virtually every member of the class of 1939. No doubt this will become
a much imitated technique for celebrating future class reunions. Ap-

ED ITORIAL BOARD
Dr. Bertram Partin, Chair

proximately, 20 members of the Class of 1939 were able to attend the

Dr. Martin Brecher
Dr. Harold Brody
Dr. Linda j. Corder
Dr. Alan j. Drinnan
Dr. james Kanski
Dr. Elizabeth Olmsted
Dr. Stephen Spaulding
Dr. Bradley T. Truax
Ms.jennifer Wiler
Dr. Franklin Zeplowitz

reunion events. The 50th reunion class won the prize for

TEACHING HOSPITALS

[rie County Med1cal Center
Kaleida HealthThe Buffalo General Hospital
The Children's Hospital ofBuffalo
Millard Fillmore Gates Hospital
Millard Fillmore Suburban
Hospital
Roswell Park Cancer Institute
Veterans Affairs Western New York
Healthcare System
Catholic Health SystemMercy Health System
Sisters of Charity Hospital
Niagara Falls Memorial Medical
Center
©The State University of ewYork
at Buffalo

Buffalo Physicia11 is published
quarterly by the State University of
ew York at Buffalo School of
Medicine and Biomedical Sciences
and the Office of Publications. It is
sent, free of charge, to alumni,
faculty, students, residents, and
friends. The staff reserves the right
to edit all copy and submissions
accepted for publication.

the highest attendance rate, with 2l members of that class able to
participate in reunion festivities.
The Spring Clinical Day program focused on women's issues, specifically breast
and ovarian cancer. Ms. Betty Friedan, a founder of the National Organization for
Women and the author of the seminal 1963 book The Feminine Mystique, gave the
Stockton Kimball lecture. She pointed out that the reasons women tend to live longer
than men may not just be due to hormones and/or genetics, but may indeed reflect
differences in life-style and, perhaps most importantly, differences in the way men and
women handle stress.
Graduation ceremonies featured Dr. D. Bruce Johnstone as keynote speaker.
Dr. Johnstone, former chancellor of the SUNY system and currently a very active
member of the University at Buffalo faculty, presented a powerful message to the
students. Having overcome serious illness himself, he could speak with authority on
the marvelous challenges and opportunities that await our graduates.
The Dean's Advisory Council also met in conjunction with the Spring Clinical Day
festivities and the annual] ames Platt White dinner to discuss the variety of issues with
which the medical school is currently grappling. The advisory council provides
invaluable advice and counsel to me as dean and represents a group of dedicated
alumni not only from this geographic region but from other parts of the country, as
well. We are all making an earnest attempt to keep in contact with alumni and, with
the help of this group and others, we plan to organize more regional alumni events
over the next year.
Busy as this time of year always is, it marks the culmination of what we are all
about-graduating physicians and scientists for the future and preparing for our next
group of students, interspersed with occasional alu mni reunions and celebrations. All
of these events represent an important cycle and one in which I hope each and every
reader of Buffalo Physician will want to participate.
I look forward to meeting with as many of you as possible during this next
academic year.

(--7

~

~"

R. Wdgh&lt;, MD

Dean, Schoo l of Medicine and Biomedical Sciences

�V 0 L U ME 3 4 , NUMBER

1

["SuMMER

1999

L 3 0 1999

2

ASpecial Place
loP Women
NEWLY ESTABLISHED

CENTER FOR WOMEN

WITH DISABILITY

by Jennifer Gold

8

14

Peak
ExpePience

HeaPing Loss
ReseaPch BolstePed

THOMAS CUMBO,

U 8

CLASS OF 1 9 9 9 ,

YEAR, $ 5 . 7 MILLION

RECOUNTS MEDICAL

PROGRAM PROJECT

EXCURSION TO NEPAL

GRANT FROM THE

RECEIVES FIVE-

NATIONAL INSTITUTES

photography by Rhea Anna

OF HEALTH

by Lois Baker

Medical School
•

GRADUATION ARRIVES!

•

MATCH DAY

Student Perspective

1 999

RESULTS

TOMORROW'S

•

PHYSICIANS CONFRONT

NEW MOUSE CALLS

CHOICE

COLUMN

•

STEP STUDENTS

Mission Improbable

by Stacey Blyth

WIN FIRST PLACE IN

SUZANNA GOODYEAR

STATEWIDE POSTER

ATTENDED MEDICAL

Classnotes

COMPETITION

SCHOOL AT AGE 5 4-

A

AN UPDATE ON HER

WHAT CAN YOU TELL

CAREER

US ABOUT YOURS?

STORI ED PAST-

by Betsy Sawyer
photography by Gary T. Truman

1999-Maria loTempio and Patrick
DiAbbrocci Celebrate Graduation Day, Saturday, May 8

THE (LASS OF

Alumni
•

SPRING CLINICAL DAY;

BETTY

FRIEDAN DELIVERS

STOCKTON KIMBALL

Closs of 1990,
Knows It's Never Too late to Follow a Dream

SuzANNA GooDYEAR,

LECTURE

•

REUNION WEEKEND

FESTIVITIES &amp;

PHOTOS

�:

JENNIFER

��I

1997,

in an effort to identify and
address these barriers, researchers at the University
at Buffalo completed one of the first assessments of
the health status of women with disabilities. The
results of the assessment were so compelling that they
spurred formation ofa multidisciplinary Center for Women
with Disability, which opened in September 1997 as
part of the Western New York Neuroscience Center at
Kaleida Health's Buffalo General Hospital (BGH).
"The health concerns of many women with disabilities are not met through the traditional health-care
delivery system. Often, these women are not treated in
the context of wellness but only in terms of their
disease," explains Carol Brownscheidle, PhD, UB clinical assistant professor in the Department of Neurology,
and director of the new center.
The health-needs assessment, which was designed
by the Women's Health Collaborative Research Group
(WHCRG) under the auspices of the Neuroscience
Center, was completed by more than 300 women with
multiple sclerosis (MS), stroke or other neurological
disorders. The respondents' median age was 45, and
half were moderately to severely disabled.
More than 20 percent of the women reported a
history of gynecological problems, such as uterine
fibroids, endometriosis, ovarian cysts, irregular menstrual periods and deterioration of MS during menstruation; a similar percentage reported experiencing
reproductive and postmenopausal health problems that
were inadequately treated. Forty percent of the women
said they were sexually inactive, while 70 percent of
those who were postmenopausal indicated they weren't
receiving hormone-replacement therapy.

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In sum, the women reported experiencing insensitivity to their special health-care needs; lack of accessible
medical equipment, such as examination tables and
mammography machines; and difficulty getting to the
various facilities for treatment of specific problems, according to Brownscheidle, who chairs and directs the
WHCRG and was instrumental in developing the survey.
Galvanized by the survey results, Brownscheidle
began work on the creation of the Center for Women
with Disability. In talking about her involvement with
the project, she is quick to acknowledge the ongoing
assistance and support she has received from others,
including Lawrence jacobs, MD, who is Irvin and Rosemary Smith professor of neurology at UB, head of the
Department of Neurology at BGH, and project director
for the ew York State Multiple Sclerosis Consortium
(NYSMSC), and Dennis Weppner, MD, MBA, UB associate professor of clinical obstetrics and gynecology and
clinical director of obstetrics and gynecology at Millard
Fillmore Hospital Suburban, both of whom serve as
co-medical directors for the center.
Today, the Center for Women with Disability is a
place where women with special health-care needs
receive a variety of services, including social and
supportive services that are intended to assuage feelings of isolation and loneliness.
For many women with MS, post-stroke impairment, post-polio paralysis, cerebral palsy, spinal-cord
injury, spina bifida or movement disorders, such as
Parkinson's disease, the neurologist is the gatekeeper
for health care, Brownscheidle notes. "We've built on
that and formed a kind of one-stop health shopping
center. When a woman comes in for stroke treatment

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�disability; they don't just deal with neurology, but OB-GYN
issues, too," notes Elizabeth Roden, who has epilepsy and
regularly attends the center. "I really wish something like
this had been around when I was first diagnosed."
Recently , the center expanded its services to include
orne women have limited movement, and
urology, with care provided by Philip Aliotta, MD.
"Bladder dysfunction is
lt
can be
quite
common with this
difficult for
population and requires
them to use the
immediate medical attenstirrups on a
tion if an infection develconventional pelvic-exam
ops," explains Epstein, who
table," explains Susan
adds that Aliotta provides
Epstein, MS, MEd, clinical
services at the center twice
coordinator for the center,
a month and sees approxiwho, along with Weppner,
mately 10 to l2 patients
developed a pelvic-exam
each
clinic day. "Dr. Aliotta
chair specially adapted for
has
conducted
research on
women with disabilities.
bladder function in patients
(See article below.) "Other
with neurological disease,
women may not be able to
and we are fortunate to have
stand upright for mammohim as part of our team,"
gram screenings or, if they
says
Brownscheidle.
are spastic, may find it difWhile
improving access
ficult to perform a breast
to
health
care remains the
self-exam. In many cases,
primary mission of the centhe women simply have a
ter, it has begun addressing
difficult time getting to the
broader, quality-of-life
different specialty offices,"
issues by offering programs
she adds.
on community-service
Although the center has
opportunities, networking,
been open less than two
social
services and careers.
years, the patients feel that
The
Outdoor
Adventure
the access it affords them to
Susan Epstein MS MEd and Denms Weppner ~D MBA, developed a pelvicProgram
offers
wilderness
one-stop health care is the
exam cho1r specially adapted 1or women with ch~o~1c uisab1ing co•di ons.
wheelchair
hikes
, and the
key to its success. "I espeWomen Helping Women Program links women with
cially like how the different types of care and services are
disabilities to volunteer opportunities in assisted-living
consolidated. These are professionals who address all
settings and nursing homes. Monthly "focus luncheons"
aspects of a woman's life and how it can be affected by
or for follow-up visits for multiple sclerosis, she can go
to other rooms in the center for a pelvic exam, a Pap
test, an ultrasound or to have her blood pressure
checked," she explains.

''s

G.xnecologic
For a woman who has multiple sclerosis (MS), it can be very difficult to
transfer from a standard 22 -inch-high wheelchair to a conventional 30-inch-high
examination table in a physician's office. For a woman with a neurological
disorder that causes spasms, loss of control of lower limbs or pain, transferring to
such a table can be impossible. Instead of being a neutral apparatus for the
provision of health care-especially gynecological care-the exam table
becomes still another barrier, both physically and emotionally.
Recognizing that access to examination tables con be a major issue for
women with disabilities in need of gynecologicol care, Susan Epstein, MS, MEd,
clinical coordinator for the Center for Women with Disability, and Dennis
Weppner, MD, MBA, UB associate professor of clinical obstetrics and gynecology,
decided to solve the problem. From the start they realized that, to be successful,

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they would need to abandon the traditional model for a gynecological exam.
The solution came one day while Epstein was at the dentist. lying in a
comfortable chair during a long procedure, she thought, "This will work."
And it did. Epstein and Weppner immediately contacted PoHerson Dental,
which has been in the specialized business of making dental chairs for more than
100 years. They identified a choir that can be lowered to 22 inches to facilitate
transfer from a wheelchair. It also had a knee break, which allows positioning
for a pelvic exam. Allen stirrups, with a boot-like fit, were aHoched in order to
increase comfort and decrease the effects of spasticity.
"This sounds like a simple solution, and it is," admits Epstein. "But, until
now, there has been nothing that would accommodate the needs of a woman
with a chronic disabling condition."

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�feature specialists who come to the center and
answer questions on health topics in an informal
setting. Some women travel from as far away as
Niagara Falls to attend these luncheons, with
transportation provided gratis by john Arnet,
president of We Care Transportation, a local
specialty transportation company. Also, valet
parking is available and can be accessed at BGH's
main entrance. Other support for the luncheons
comes from Biogen, a biotechnology firm that
makes the drug Avonex TM, for treatment of MS.

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no ther quality-of-life project
under way is the development of a
Career Center, scheduled to open in
fall 1999, which will focus on
re-employment of clients by instruction in such
areas as resume composition, interview skills,
managing home finances and self-esteem building. A fully accessible computer lab will introduce
clients to basic PC and Internet skills. Provisions of the
Americans with Disabilities Act, job Accommodation
Network and opportunities available through
vocational education will be presented to clients.
Recent statistics show that lack of employment can
lead to feelings of loneliness, pessimism, morbid or
gloomy thoughts and self-pity in approximately 75
percent of unemployed disabled women, in comparison
to 25 percent of employed disabled women, according
to Brownscheidle. "Employment is viewed as a productive use of time that improves outlook on life and
augments one's contribution to society, whether it
involves full-time or part-time work. The Career Center
will provide career counseling and aptitude testing, as
well as individual and small group sessions to achieve
these goals," she says.
Carolyn Miller, who regularly visits the center since
her diagnosis with MS, says living with a disability can be
extremely isolating. "It's a lonely life," she relates, adding
that she sometimes feels "vulnerable and depressed"
about her inability to enjoy many of the activities she used
to, such as volleyball and waterskiing.
"It's nice to be involved with the other women," says

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Ilona Tylwalk, who has MS. "There's an interchange of
ideas, and we can talk about our problems and
different illnesses-because not everyone has MS.
"The lunch lectures are great," she adds. "''ve never
been disappointed by one."
The center's educational goals extend beyond the
patient population in an effort to reach health-care
professionals, as well. "Women with disabilities are just
as susceptible to the three leading causes of death in
women in the United States-heart disease, cancer and
stroke-and therefore should be screened and counseled accordingly," says Brownscheidle. Unfortunately,
the diagnosis of a major disease, such as MS, often
overshadows every other aspect of a woman's health,
with the results being that broader health-care concerns, including access to primary care, are overlooked.
"We listened to our patients and heard the same
thing over and over again-that access issues were
often ignored and gynecological examinations were
demoralizing and impersonal. They just didn't feel
comfortable," says Brownscheidle. "Some of the women
have even been asked by their gynecologists why they
wanted to know about sexually transmitted diseases or
birth control. Did they actually have a sex life7"

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�Despite such concerns, Brownscheidle states that
progress is being made toward better understanding and
that "even within the past year in this country, the healthcare profession as a whole has started to focus more
closely on specific health issues affecting women with a
disabling condition."
Weppner emphasizes that the center is not only taking
a proactive role in treatment and education, but is also
furthering research efforts by ensuring that the women
who visit the center are enrolled in the NYSMS registrythe largest population-based cohort of MS patients
reported to date. The research implications of this database
are enormous, he explains, and the close association with
UB's School of Medicine and Biomedical Sciences adds
impetus to the center's ability to contribute to the treatment of neurological diseases in general, as well as to the
comprehensive care of women, in particular.
"By approaching our research from a multidisciplinary
perspective, as well as looking at data from the perspective of gender differences for these diseases, we may
discover information we might not have otherwise found ,"
Weppner says.
Since its inception, the Center for Women with
Disability has attracted the attention of national healthcare organizations, including the New York State Depart-

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ment of Health, Baylor University and the Mayo Clinic,
which last spring sent representatives to Buffalo to visit
the center. ln addition, Brownscheidle was invited to
present information about the center and the health-care
assessment survey at the American College of Obstetricians and Gynecologists 1998 annual meeting in New
Orleans and at the Women's Health Issues in Multiple
Sclerosis Roundtable in Houston. She also moderated a
national conference on women with MS and their healthcare concerns in Amelia Island , Florida, in june 1998.
Although the center has not been widely advertised ,
patients, too , are finding out about it, and their numbers
are growing steadily. "Patients are hearing about us ," says
Epstein. "Recently, a woman who is an amputee called us
to say that she was so thankful for the center because she
hadn't had a Pap smear in 10 years. "
Exposure and recognition like this is likely to engender continued interest in the growth and development of
this unique center for women with disabilities, leading to
even more comprehensive services for its patients. However, for Leona lrsh , an Episcopal priest diagnosed with
MS, the fact that the center even exists is like an answer
to a prayer. "I cannot say enough about what they are
trying to do for us. It means so much that they are looking
at us as whole people. " +

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��Class of 1999

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�started about one year before my actual departure, when I called Dr. Brendan Thomson,
whom Dr. Copley had listed as a contact person at the close of his article. Dr. Thomson
is a UB alumnus (Class of 1970) who resides in Phoenix and actively runs an ongoing
Nepali-American exchange program. He had been the guiding inspiration behind
Dr. Copley's decision to travel to Nepal and had accompanied him on his journey
When Dr. Thomson returned my call the next day,
we realized that we are both
graduates of Canisius College
and UB medical school and
found that our shared jesuit
heritage resonated well. He
gave me names , numbers and
the advice I needed to begin
organizing the most daunting task I
had ever attempted. Specifically, my
goals were to coordinate a medical
experience for myself in a location
halfway around the world, to complete my residency applications prior
to leaving, and to not get killed or lost
once I arrived at my destination. The
details involved in implementing
these goals were tremendous and the
obstacles and stresses, extraordinary,
but my zeal for adventure and the
critical support of my family, girlfriend and several local members of
the medical community enabled me
to accomplish what I had set out to
do. The hardest part of this excursion, I have since realized , was not
the trip to Nepal itself, but convincing myself early
on that it was worth all the sacrifices and risks I was
taking. Having gone and returned, I no longer have
any doubt that it was the best thing I could have
done , as the trip contributed to my medical education and personal growth in ways I am only now
beginning to fully understand.
I left for the Far East in September of 1998 not

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knowing what to
expect but strongly
motivated by a
lifelong interest in
biology , travel ,
wilderness medicine and foreign
cultures. My plans
to "go it alone "
changed for the better at the last minute, when DJ,
a good friend of mine from California, decided to
come along.
Arriving in Bangkok, Thailand, we settled in for a
14-hour layover priorto leaving the next morning for
Kathmandu. As the sun was rising, we boarded the
plane, which was filled with a motley assortment of
colorful passengers, including local Nepali people,
trekkers and climbers, and even some celebrities
coming from around the world. I met and talked with
jon Krakauer, author of Into Thin Air, after which I
realized this was going to be a unique experience.
Once we took off, I soon received my first
dose of the Himalayan mountains , watching as
the peaks cut through a thermocline layer of
clouds like islands. The jet stream over the
Indian subcontinent skims over Mount Everest
and a comet-like trail of ice is commonly seen
trailing off the peak. We wound through these
giants until we approached the emerald green
valley of Kathmandu far below.
When we finally landed, I was overwhelmed
by sensations I had only previously read about
in books. The air was muggy from the jungles
that surround the city, the sun was extremely
hot and masses of people were everywhere,

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Tibetian monks in the village of Pokhara in western Nepal invite Tom, left, and DJ to join them in a pick-up game of hockey sack.
Pictured below, a monkey looks on as bodies are cremated on a pyre at Pashupatinath Temple overlooking the Bagmati River.

although few seemed to have any real place to go.
A loneliness and desperate feeling of emptiness
consumed me as I pondered the enormity of
spending more than six weeks in such a place.
E\\ Co:--;cEPTS ABOL T LIFE, DEATH A\D BAsiC ExiSTE ·cE

Once we boarded a epali cab and were under way,
I was able to appreciate for the first time both the
poverty and the history ofthis ancient place. Looking
out my window, I marveled at the small crowded
houses, dirt roads, completely disorganized traffic
and hordes of people-a mosaic of life that exists
under the watchful eyes of the Buddha, which peer
from the many temples and stu pas that dot the region.
Religion in Nepal is a blend of Buddhism from the
north and Hinduism from the south, both mixed with
a touch of Animism and Christianity. This blending
makes the country a true melting pot and a place
where people are very accepting of diverse philosophies and practices. Little did I realize how my
perceptions of death, life and basic existence would
be challenged and modified during my stay.
My mentor during my stay in epa! was Dr. Buddha
Basnyat, a local physician who had befriended
Dr. Thomson during his first visit to Nepal years
before. At the time, Dr. Basnyat had been intent on
completing an internal medicine residency in the
United States, and Dr. Thomson had helped place him
at a Phoenix hospital and had invited him to stay in his
home during the three-year fellowship .

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When we arrived at Dr. Basnyat's
home, I was relieved to finally meet
him and his wife and their three children. We were immediately escorted
to their family room, where we exchanged "namastes" (a epali greeting meaning "I salute God in you"),
after which we were offered tea. DJ and
I soon realized that we could not have
been blessed with a nicer family to ease
our transition. Through the Basnyats,
we were introduced to the many facets
of Nepali culture, including its festivals, traditions and arts. One such art
was the practice of relaxation, which
stems from the belief in Nepal that
work and leisure time are of equal
importance. As a result, hours each
day are devoted to relaxation and cultivating a balance between rest and
activity. DJ , the Californian, adapted
immediately; this medical student, in
contrast, had a much harder time with
the practice!

A MIXTURE

OF PEOPLE -\\0 DISEASES FRO\!
AROt.; D THE PL.-1.'\ET

In arranging for my excursion to Nepal, the plan was
that I would "shadow" Dr. Basnyat during his work
day at a general medicine clinic, where he is in

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�private practice with several partners. I would also
accompany him on general rounds at the local
hospital , conduct research with the Himalayan
Rescue Association (HRA) and have some free time
to go trekking.
I spent the first two weeks in Kathmandu adjusting to my new environment, finding decent $3-aday rooms and struggling daily to maintain perspective. Patients at the clinic were truly a mix from all
over the planet, which is to be expected when working roughly 180
degrees oflongitude from Cleveland.
A simple fever workup takes on
new meaning when a patient has
recently been in India, sporadically
taken his Lariam (anti-malaria medicine), flown to Lhasa, Tibet (a gain
of about 3,200 meters in altitude in
one day), cannot remember which
vaccines he received, and has come
to Kathmandu where he has not been
too conscientious of sanitary conditions and has "reveled in the local
festivities. " I saw much gastrointestinal illness, ranging from amoebas
to cyclospora; sexually transmitted
diseases; tuberculosis of all manifestations; rabid dog bites; infected leech
bites; a host of dermatology, from
psoriasis to cutaneous tuberculosis;
and malaria. We also had a good
share of common internal medicine
problems , but these were often
quite advanced.
At Patan Hospital I saw untreated
malaria , typhus, japanese encephalitis, chronic obstructive pulmonary
disorder, anemias, amoebic liver
abscesses, rabies and several other
exotic maladies. I experienced for
the first time the frustration of limited resources, and I developed respect for the local physicians and
those whose religious devotion calls
them here. While I did have a difficult time adjusting to the poverty of
these patients, especially the children, I was impressed by the family
presence in the hospital and by how
much responsibility the patients'
relatives assume.

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LHR. L G RESPEC r 1OR \\- JLD PLACES

In addition to my experience at the clinic and hospital, I was also very fortunate to work with Dr. Basnyat
at the HRA. This organization coordinates rescue
missions in the mountains, staffs physicians at strategic trekking and climbing routes, educates trekkers
and studies Himalayan climate and biology. Dr.
Basnyat's interests lie in high-altitude medicine and
extreme environmental physiology. If they live, individuals who are seriously ill at altitude are likely to
become patients of Dr. Basnyat's back in Kathmandu.
Especially poignant to me in my work with the
HRA is a case of a European man who ascended too
high, too fast, along the Everest route. He ended up
with a horrible case of cerebral edema and was found
unresponsive with a pulse-oxygen rate of 38 percent
(a rough measure of oxygen saturation in the blood,
with the normal rate being about 90 to 100 percent);
he never recovered full brain function. More than
anything, this furthered my respect for the power of
these and other wild places for both the sudden
climatic changes that can cause havoc and the subtle
insults that can accumulate over time.
This firsthand exposure to the field of geographic
medicine-which offered me a chance to combine
my love of biology with medical work-confirmed
for me that this is a discipline I will certainly
continue to explore in the years ahead. At the HRA,
I had a blast learning the local geography, giving
advice to climbers, lecturing about acute mountain
sickness (AMS) , designing research projects and,
most notably, helping Dr. Basnyat develop theories
to explain data he collected from a recent study of
his. A theory I developed to help explain one possible component of AMS pathogenesis is currently
being tested in the vicinity of Mount Everest, and
my frequent daydreams are a testament to how
excited I am over the possibility of having conjured
a novel idea. I am fascinated by exotic diseases and
intrigued by the prevention of such problems,
especially when the added complexities of political
and cultural differences are factored in.

A.

U\GUDED TREK L THE WILDER. ESS

Soon it was time for DJ and me to leave Kathmandu
for a long-planned 10-day trek in the Himalayan
wilderness. We went without guides , often resorting
to a global positioning system for direction. I had
more than my share of leeches, headaches, pain,
loneliness, silence and time to think while trudging
through the remote terrain.

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�While on o bockcountry trek to Annopurno Sonctuory,Tom Cumbo, leh, come to the oid of o porter who cut his foot with on ox.

I learned that this discomfort is the price one
pays for the spectacular views normally reserved
for IMAX theaters and the wisdom that potentially
unveils itself during times of quiet reflection. We
were blessed with cloudless mornings, interaction
with the natives and time to think about our priorities in life. Dr. Basnyat's father, a devout Hindu, had
previously given us lessons on filtering sensations
and becoming pleasantly detached from our
environment, and the extremes of emotion and
physical sensation that characterized our trek
provided plentiful fodder for this practice.
The Nepal wilderness is harsh, featuring constant
avalanches, landfalls, extreme variations in altitude
and temperature, wild animals, disease and, at times,
mysterious inhabitants. Clouds seem alive as they
stream over the high passes. Glaciers creak and moan
before unleashing rolling splinters of ice. Sinkholes
open in the glacial field, unexpectedly swallowing
tons of debris. Small streams become roaring rapids
farther down the slopes as they swell with runoff from
the icy peaks above. Buddhist prayer flags break the
characteristic silence of the open range with crisp flaps,
sending constant meditative mantras into the open
air. As a final destination, we climbed into Annapurna
Sanctuary-a holy land at 5,000 meters that is
surrounded by 8,000-meter peaks--where we sat for
days, staring in profound awe at the vast panoram;;~ .
I also had my share of patients on the trek, which
was especially frightening because, for the first time
in my medical career, I was working completely
alone. I treated climbers who had clear signs of acute
mountain sickness and impending complications,
others who were maladjusting psychologically and a

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local who sliced his foot with an ax
and was bleedingprofusely.Itiscomical now to picture myself three days
from civilization, using a latex glove
with a small hole cut in the finger to
irrigate the wound while getting loose
translations from the patient's family
and shooing curious animals away.
Improvisation is often necessary in
these circumstances.
THE \\ tSDO\t

Gu

ED FRO\t SLCH AVE. TLRE

My time in Nepal was one of the most challenging
experiences I have ever had. I spent the majority of
the trip adjusting to one tough emotion after another, interspersed with the most tremendous highs.
The wisdom gained from such a venture will sei¥e
me well for the rest of my life. What did I learn? In
essence, I learned about the value of moderation
and balance and the importance of family and close
friends. I also learned that very rarely does the
worst-case scenario in a particular situation actually materialize; that one must practice what one is
passionate about; and that life can be cruelly unfair.
This year-long project, with all its stresses and
rewards, has altered my life dramatically. There
were several moments when I felt sensory
overload was imminent from the intensity of my
experiences. Things I thought were constants have
vanished, often painfully. Insights and opportunities have helped fill the void and offer direction.
Home again, I thank God for these challenges, the
maturation they have spurred and the opportunities they have unleashed. +

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�Funding Bolsters Research
on Hearing Loss
UB

RECE IVES

$5 .7

MILLION PROGRAM

PROJECT GRANT FROM

NIH

he University at Buffalo has received a five-year, $5.7 million
program project grant from the National Institu tes of Health
(NIH) to expand studies aimed at understanding and treating
acquired hearing loss, a condition that affects approximately
28 million people in the United States alone.
The grant funds four projects in which
investigators are studying the function
of the peripheral and central auditory
system in an effort to determine how
and why noise and certain therapeutic
drugs cause loss of hearing. Principal
investigator is Richard ]. Salvi, PhD,
professor of communicative disorders
and sciences in the College of Arts and
Sciences, clinical professor of otolaryngology and neurology in the School of
Medicine and Biomedical Sciences, and
codirector of UB's Center for Hearing
and Deafness.
In awarding the grant, the IH is
supporting UB's efforts to build on
significant contributions made over
the past 12 years by an internationally
recognized research group in the
Center for Hearing and Deafness, a
multidisciplinary effort involving 30
scientists from eight departments and
three schools within UB.
"This grant is wonderful news for the
university," says UB President William
R. Greiner. "It will enable Professor
Salvi and his team to expand their
pathbreaking research into the causes
of acquired hearing loss. The outstanding work conducted by this group is a
stellar example of the interdisciplinary

research that we foster at UB. Their
studies promise not only to advance
scientific knowledge about acquired
hearing loss, but to benefit millions of
people who suffer from this affliction.
We are proud that our center received
this prestigious NIH grant and look
forward to its continued success as a
worldwide leader in its field ."
UB Provost David]. Triggle
notes that program project
grants provide funding that
makes it possible for scientists
to research several related
directions simultaneously.
FOLR OvERLAPPI"&lt;G RESEARCH THEMES

The Center for Hearing and Deafness
was established in 1987 by Donald
Henderson, PhD, professor of communicative disorders and sciences and
otolaryngology, and Salvi, both of whom
came to UB that year from the University of Texas at Dallas.
They were joined in the mid-1990s
by researchers Robert F. Burkard,
PhD, associate professor of communicative disorders and sciences and
otolaryngology, and Sandra L.
McFadden, PhD, research assistant
professor of communicative disorders

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and sciences and psychology.
Today the center is focusing its
research on four overlapping themes
that form the basis for the current
program project grant. These projects
target ( 1) molecular and cellular mechanisms of hearing loss; (2) effects of
ototoxic agents and noise on cochlear
function ; (3) functional alterations of
the central auditory brain regions after
partial or temporary hearing loss; and
(4) the role of the ears' inner hair cells in
the brain's processing of auditory stimuli.
"To understand why a patient
experiences difficulty in processing

hysician

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�New W. M. Keck Foundation
Center for Computational Biology
BY

complex sounds, we need first to understand how the auditory system processes
acoustic information along the entire
auditory pathway," explains Salvi.
"Damage that originates at the
periphery, or inner ear, can cascade
through the system, disturbing activity
throughout the entire auditory pathway,
even spilling over to other sensory, motor, cognitive and emotion centers. This
functional reorganization, or plasticity,
is poorly understood because of a lack of
an integrative research approach to acquired hearing loss. Our project provides
such an approach, " he adds. +

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CHAMBERLAIN

AND

EL L E N

G OLD BAU M

·D
grant from the California-based W.M.Keck Foundation will
move the University at Buffalo to the forefront in single-molecule research, an area of
investigation so promising that the journal Science recently devoted an entire issue to it.
The grant-funding the creation of a new W. M. Keck Foundation Center
l
for Computational Biology at the University at Buffalo-will allow a team of
researchers in the School of Medicine and Biomedical Sciences to purchase high-speed
computers that will greatly accelerate their study of the activity of ion channels. Ion
channels are protein structures that regulate the flow of electrical currents in cells; when
malfunctioning, they can lead to a wide spectrum of diseases.
The UB researchers-Frederick Sachs, PhD, and Anthony l. Auerbach, PhD,
professors of physiology and biophysics, and Feng Qin, PhD, research assistant professor
of physiology and biophysics-have developed software programs that are revolutionizing the way scientists interpret ion-channel activity, which is so complex and timeconsuming that, until recently, many researchers simply gave up on it. With their "QUB"
software, researchers around the world are able to discover in minutes how long it takes
for an ion channel to change shape, which enables them to understand how it functions,
or malfunctions. Previously, such calculations would have taken months.
According to Sachs, it was Feng Qin-ot the time a graduate student and someone
whom Sachs describes as "brilliant"-who developed the algorithms on which the
software is based. "For 20 years, scientists have been collecting data on the random
movements of molecules, but they didn't know how to interpret this information," says
Auerbach. "Qin made several breakthroughs, and now the analysis is relatively easy."
Scientists and software vendors have responded positively to the methods the UB
team developed, and the instructional workshops that they hold are well attended. "Our
programs are becoming the 'gold standard' for ion-channel research," says Auerbach.
"The Keck grant is important to our future because it provides us with computing
power that will allow us to push the limits of molecular dynamics," he adds.
The Keck Foundation grant supports work that is part of an ongoing structuralbiology initiative at UB; it also builds on other recent corporate grants that are helping to
make UB one of the top-1 0 supercomputing sites in the U.S.
Founded in 1954 by the late W.M. Keck, founder of the Superior Oil Company, the
W. M. Keck Foundation is one of the nation's largest philanthropic organizations. Its
grants focus primarily on pioneering efforts in the areas of higher education, medical
research, science and engineering. +

PROGRAM PROJEa INVESTIGATORS, /eft to right, Sondra l.
McFadden, PhD, Donald Henderson, PhD, Richard J.
Salvi, PhD, ond Robert F. Burkard, PhD.

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&lt;·

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®

Commencement for the School of Medicine and Biomedical
Sciences at the State University of New York ot Buffalo wos held on
Moy 8, 1999, ot the Center for the Arts on the North Campus.
This year, the school conferred 144 MD degrees, 2 MD/PhD
degrees, 35 PhD degrees and 52 master's degrees. Graduates
induded students from the Graduate Division of Roswell Pork
Cancer Institute.
Pictured center, left to right: David Pawlowski,

Daniel Perregoux, Stephen Przynosch ond Mary bsePuthiyomodom.
Clockwise, from upper left: 1 faculty ond graduating

PhOs Tiejon Wu, Or. Germaine Buck, Or. Arthur Michalek, Or. loon
Dorn, Enrique Schistermon ond Jeanne Perla 2 Malcolm Heagle II
3 Honored Speaker Or. D. Bruce Johnstone 4 Or. Richard Sorkin,
Brian Duffy and Or. Frank Schimpfhauser 5 Mary Rose
Puthiyomodom ond family 6 Raquel Tonuzi.

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�Wiring Medicine for the Future
LA S ARE uNDER VvAY at the University at Buffalo

CONTINUING MEDICAL EDUCATION (CME) .

CALENDARS OF LOCAL AND REGIONAL PROGRAMS AT

UB AND THROUGHOUT WESTERN NEW YORK .

CALENDARS OF NATIONAL AND
INTERNATIONAL MEETINGS.

CATALOGS OF PRODUCERS OF CME PROGRAMS.

ONLINE INTERNET CME COURSES.

to establish an online medical-information system to
serve the educational, research, patient care and administrative needs of UB's dispersed multi-institutional
health-care network. Funding in support of this futuristic planning has been provided to the university's
Health Sciences Library through a two-year, $283,000
Integrated Advanced Information Management System
(!AIMS) grant from the National Library of Medicine ( LM).
Gary Byrd, director of the Health Sciences Library and the
project's principal investigator, says the system will offer
ready access to a virtual, knowledge-based library, as well as
clinical-care, research and educational information resources.
"The goal is to provide health-information resources that
are organized and available across an electronic infrastructure that will enhance the processes by which health-care
professionals teach and learn, conduct biomedical research,
administer health organizations, provide patient care and
offer consumer health information," he says.
The Health Sciences Library will collaborate on the project
with the Schools of Health Related Professions, ursing,
Dental Medicine, Pharmacy, and Medicine and Biomedical
Sciences, as well as with affiliated health-care organizations.
For participating institutions and organizations, the project
is expected to optimize and integrate information-technology
goals and strategic priorities; help make effective use of shared
expertise and technology; and offer an adaptable, sustainable,
high-quality and cost-effective medical-information network
with links to many sources of health-care data.
The !AIMS grant will also provide programs and tools to
help educate and train individuals to use easy-to-navigate,
convenient and timely point-and-click workstations.
Through these workstations, users will be able to access
information independent of time constraints, physical location, organizational affiliation or workplace technology.
The lAlMS program was initiated by the NLM, a division
of the Nationallnstitutes of Health, in response to a report
in the early 1980s by the Association of American Medical
Colleges on the role oflibraries in information management.
The report recommended that academic medical centers
develop information networks to help integrated medical
units communicate better.
Co-principal investigators for the grant are Bruce
Holm, PhD, associate dean for research and graduate studies
in UB's School of Medicine and Biomedical Sciences, and
Francis Meyer Jr., vice president for information systems
and technology for Kaleida Health. +
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P ATRICIA

Summer

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g

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Students Who Are aSTEP Ahead
OUR BufFALO-&gt;\REA HIGH SCHOOL students participating in the
Science and Technology Entry Program (STEP) at the
University at Buffalo School of Medicine and Biomedical
Sciences were awarded first place in the Natural Science
Category I for a poster they presented at the STEP Statewide Student
Conference held May 22-23, 1999, in Syracuse, New York.
The poster, titled "Heart Health utrition: The Regulation of Homocysteine by
Folic Acid, Vitamin B-6 and B-l2Intake,"
was prepared and presented by Latasha .
Evans, a junior at Holy Angels Academy;
Lynette A. Gholston, a sophomore at Villa
Maria Academy; Nichole M. Gonzales, a
sophomore at iagara Wheatfield Senior
High School; and Aprile Hollinsworth, a
sophomore at Buffalo Traditional School
#192. The group received $250 for the
first place finish and each member was
presented a certificate.
The purpose of the STEP Program is
to assist underrepresented minority or
economically disadvantaged secondary
school students in acquiring the prerequisite skills necessary to pursue
pre-professional or professional educational programs in scientific, technical
or health-related fields, according to
Carolyn Hamilton, EdD, assistant dean
for Minority Affairs at UB.
STEP is open to qualified students in
grades 9 through 12. Those who earn
entrance to the program complete a
two-week orientation, after which they
begin the Summer Component, which
places them in a university-affiliated
hospital where they gain exposure to
science and health care through work
experience. "This experience is enriched
by field trips to the UB South Campus,
where the students visit the
Neuroanatomy Museum, learn how to
conduct research on the Internet in the

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students to the statewide conference,
says the four young women researched
their winning poster presentation on
the Internet and at the Health Sciences
Library, as well as contacted a lentil
producer in Idaho to obtain dietary
information, food samples and recipes.
In addition, Murray Ettinger, PhD,
Distinguished Teaching Professor of
Biochemistry, assisted the students in
illustrating a molecular model of
homocysteine; and Raymond Dannenhoffer, PhD, in the Department of
Anatomy and Cell Biology, provided the
students with two heart models. Dennis
Nadler, MD, associate dean for Undergraduate Medical Education, andj ohn R.
Wright, dean of UB's School of Medicine and Biomedical Sciences, also
provided support for the students.
"The judges reviewing the posters
interviewed the students about their
research and each was able to answer
a number of questions in a very knowledgeable way," says Coplin. "They were

Health Sciences Library, participate in
sessions in the Gross Anatomy Laboratory and assist and observe medical
students who are examining standardized patients," says Monyuette Y.
Coplin, STEP program coordinator in
the Office of Minority Affairs. "Many of
the students also attend UB's Mini-Med
School and Mini-Vet School," she adds.
During the academic year, the
students attend Saturday classes
in biophysics, biochemistry, applied
math and computer
science that are
taught by first- and
second-year medical
students. "The medical students are good
role models and will
often informally
share information Left to right: Aprile Hollinsworth, lynette Gholston, Nichole Gonzales, latasha Evans
with the STEP stu- and Mrs. Monyuette Y. Coplin, STEP's program coordinator at the University at Buffalo.
dents about how best
to prepare for careers in health care or poised throughout the competition
science," says Hamilton.
and we are all very proud of their
In addition to the hospital experi- accomplishment." +
ence, academic instruction and laboratory exercises, students can avail STEP and its activities are supported by a
themselves of a Tutorial Program if they grant from the New York State Education
are experiencing difficulty with school- Department. For more information on the prorelated subjects. Also, to ensure they gram at UB, contact Monyuette Y. Coplin in
have the best possible chance of meeting the Medical STEP Office at (716) 829-2802;
their career goals, the students receive or e-mail her at myc@acsu.buffalo.edu.
vocational and career counseling.
- 5. A. UNGER
Coplin, who accompanied the

Physician

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~
I

Renee Abderhalden· Friend
Internal Medicine, SU Y/Buffalo
Graduate Medical-Dental Educauon
Consortium
BUFFALO, NY

Match Day 1999

Bettina Ackermann
Pediatrics, Eastern Virginia

Stephanie Babcock
Pediatrics, Cleveland Clinic
CLEVELAto;D, 0 H
Lisa Balduf
Surgery, Universtty of New Mexico
School of Medicine
ALBUQUERQUE,

M

Medtcal School

Fayyaz Barodawala
Medicine (Prelim), SU Y/Buffalo

ORFOLK, VA

Daniel Alexander
Orthopaedics, Henry Ford Health
Science Center
Detroit, Ml

Graduate Medical-Dental Education
Consortium, Buffalo, NY; Diagnostic
Radiology, Dartmouth-Hitchcock
LEBANON, N H

Martha Aliwalas
Family Practice, University of
Pittsburgh Medical Center,
St. Margaret

Todd Battaglia
Orthopaedics, University of Virginia

PITTSBURGH, PA

Michael Ament
Medicine (Prelim),

Renee Baughman
Obstetrics/Gynecology, SUNY/Buffalo
Graduate Medical-Dental Education
Consortium

Untversity of Colorado;

BUFFALO,

CHARLOTTESVILLE,

vA

Y

Neurology, University of
Colorado
DENVER, CO

Lynn-Marie Aronica
Obstetrics/Gynecology,
SU Y/Buffalo Graduate
Medtcai-Dental Education
Consortium
BIJFFALO, NY

Kurt Benham
Ophthalmology, SUNY/Buffalo
Graduate Medical-Dental EducatiOn
Consortium
BUFFALO,
Y

Florence Bero
Family Practice, University of
Vermont/Fletcher Allen
BURLINGTON, VT

jorge Arzola Marrero
Surgery (Prelim), SU Y/Buffalo
Graduate Medical-Dental
Education Consortium
BuFFALO,

Y

Jason Borton
Emergency Medicine, SU Y/Buffalo
Graduate Medical-Dental
Education Consortium
BUFFALO,

Tahsina
Atiquzzaman
Family Practice,
Stony Brook
Teaching Hospital
STONY BROOK, NY

®

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�Amy Breden berg
Family Practice, john Peter
Smith Hospital
FORT WORTH, TX

Thomas Cimato
Internal Medicine, Hospital of the
University of Pennsylvania
PHILADELPHIA, PA

William Breen Ill
Family Practice, Eastern Maine
Med1cal Center
BANGOR, ME

Thomas Cumbo
Internal Medicine, johns Hopkins
University/Sinai Hospital of
Baltimore
BALTIMORE, MD

Ann De Nardin
Family Practice, SUNY/Buffalo
Graduate Medical-Dental
Education Consortium
BUFFALO, NY

Molly
Susan Esposito take to
the air waves with their news.

Andrea deRosas
Medicine (Primary), SUNY/Buffalo
Graduate Medical-Dental
Education Consortium
BUFFALO, NY

Susan Esposito
Emergency Medicine,
johns Hopkins Hospital
BALTIMORE, MD

Deidre Brown
Family Practice, SUNY/Buffalo
Graduate, Medical-Dental Education
Consortium
BUFFALO, NY

joyce Cummings
Pediatrics, SUNY/Buffalo Graduate
Medical-Dental Education Consortium
BUFFALO, Y

Andre Dick
Surgery, Penn State Geisinger
HERSHEY, PA

Brian Cambi
Internal Medicine, Yale-New Haven
Hospital
EW HAVEN, CT

Patrick D' Abbracci
Internal Medicine, University of
Southern California
Los ANGELES, CA

Melissa Dilanni
Internal Medicine,
Brown University
PROVIDENCE, Rl

Christopher Carlson
Internal Medicine, University of
Michigan Hospitals
ANN ARBOR, M!

Chantell Dalpe
Obstetrics/Gynecology, State University
of ew York Health Center
SYRACUSE, y

Michael Docherty
Internal Medicine, University of
Cahforn1a, San Diego Medical Center
SAN DIEGO, CA

Andrew Fagelman
Urology, Maimonides Med1cal Center
BROOKLYN, Y

John Carter
Emergency Medicine, SUNY/Buffalo
Graduate Medical-Dental Education
Consortium
BUFFALO, Y

Patricia Danaher
Family Practice,
Washington Hospital
WASHI"'GTON, PA

Brian Duffy
Surgery, Eastern Virginia
Medical School
ORFOLK, VA

Tanya Falkowski
Pediatrics, University Maryland
Medical Center
BALTIMORE, MD

Christopher Deakin
Psychwtry, SUNY/Buffalo Graduate
Medical-Dental Education
Consortium
BUFFALO, y

David Dugan
Surgery (Prelim), SU Y/Buffalo
Graduate Med1cai-Dental Education
Consortium
BUFFALO, Y

Barbara Fare
Medicine/Pediatrics, Orlando Reg10nal
Med1cal Center
ORLANDO, FL

Barbara DeGuiseppe
Psychiatry, SUNY/Buffalo Graduate
Medical-Dental EducatiOn
Consortium
BUFFALO, NY

Nadine Duhan
Surgery, Rush-PresbyterianSt. Lukes
CHICAGO, IL

Albert Chu
Pathology, Hospital of the University
of Pennsylvania
PHILADELPHIA, PA

Lynn Dunham
Pediatrics, SU Y/Buffalo Graduate
Medical-Dental Education Consortium
BUFFALO, Y
jessica Edwards-Reich
Obstetrics/Gynecology, Long Island
jewish Hospital
NEW HYDE PARK, NY
Philip Ehrlich
Medicine (Prelim), Alton Ochsner
Medical Foundation, New Orleans,
LA; Ophthalmology, Louisiana State
University Eye Center
EW ORLEANS, LA

Douglas Evans
Surgery (Prelim), SU Y/Buffalo
Graduate Medical-Dental
Educauon Consortium,
BUfFALO, Y;
Orthopaedic Surgery, SUNY/
BuFFALO Graduate Medical-Dental
Education Consortium
BuFFALO, NY

Craig Feinberg
Internal Medicine, George Washington
University
wASHINGTON, DC
Victor Fila dora II
Medicine (Prelim), SUNY/Buffalo
Graduate Medical-Dental Education
Consortium
BuFFALO, NY;
Anesthesiology, Brigham &amp; Women's
Hospital
BOSTON, MA
Oren Fix
Internal Medicine, Boston University
Medical Center
BOSTON, MA
James Flaherty
Internal Medicine, McGaw Medical
Center-NW
C!liCAGO, !L
John Fojtik
Emergency Medicine, MCP Hahnemann
University
PHILADELPHIA, PA

Corey Harrison, center, looks to the future.

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Karen Foti
Pediatrics, Tulane University
School of Medicine,
ew Orleans, LA
Timothy Fox
Emergency Medicine,
Maine Medical Center,
PORTLAND, ME

Medicine (Prelim), University of Utah
Affiliated Hospitals
SALT LAKE CITY, UT;
Radiation Oncology, University of Utah
Affiliated Hospitals
SALT LAKE Cny, UT
Malcolm Heagle II
Pediatrics, University of South
FLORIDA, TAMPA, FL

Elizabeth Francis
Medicine (Prelim),
Mary Imogene Bassett
Hospital, Cooperstown, Y;
Dermatology, Penn State Geisinger
DANVILLE, PA

Brandy Helminiak
Emergency Medicine, Ohio State
Umverslty Medical Center
COLUMBUS, OH

Natasha Frangopoulos
Surgery (Prelim), Mt. Sinai Hospital,
New York, NY; Otolaryngology,
Mt. Sinai Hospital
EW YORK, NY

John Henry
Medicine (Prelim), University of
Rochester/Strong Memorial Hospital
ROCHESTER, NY;
Neurology, University of Rochester/
Strong Memorial Hospital
ROCHESTER, NY

Eric Fung
Surgery (Prelim), State Umverslty of
ew York Health Center, SYRACUSE,
Y; Otolaryngology, State Umversity
of New York Health Center
SYRACUSE, Y

Renee Hernandez
Internal Med1cine, Einstein!Montefiore
BRONX, NY

Karen Gerber·Vecsey
Pediatrics, SUNY/Buffalo Graduate
Medical-Dental Education
Consortium
BurrALO, NY
jennifer Griffith
Surgery, University of Rochester/
Strong Memonal Hospital
ROCHESTER, NY
Molly Harrington
Pediatrics, Maine Med1cal Center
PORTLAND, ME
Corey Harrison
Emergency Medicine, University of
Massachusetts
WORCESTER, MA
Lisa Hazard

Maria loTempio
Otolaryngology, University of California
Los Angeles Medical Center
Los ANGELES, CA
Stefan lucas
Anesthesiology, University of
Rochester/Strong Memonal Hospital
ROCHESTER, Y

Kristine Klein
Obstetrics/Gynecology,
Albany Medical Center Hospital
ALBA~Y.

Patricia Lugar
Internal Medicine, McGaw Medical
Center-Northwest
CHICAGO, IL

y

Mitchell Kolker
Surgery (Prelim), SUNY/Buffalo
Graduate Medical-Dental Education
Consortium
BUFFALO, Y;
Otolaryngology, SU Y!Buffalo
Graduate Medical-Dental Education
Consortium,
BUFFALO, Y

Kelly Holes
Family Practice, SUNY/Buffalo
Graduate Medical- Dental Education
Consortium
BUFFALO, NY

Brett Mascia
Pathology, University of Virginia
CHARLOTTESVILLE, v A
lucy Mastrandrea
Pediatrics, SUNY/Buffalo Graduate
Medical-Dental Education
Consortium
BUFFALO, NY

Margaret lafferty
Pediatrics, SUNY/Buffalo Graduate
Medical-Dental Educauon
Consortium
BUFFALO, y

Teague Horton
Pediatrics, University of Virgima
CHARLOTTESVILLE, VA
Shannon Howe
Pediatrics, SU Y!Buffalo Graduate
Medical-Dental Education
Consortium
BuFFALO, NY

Timothy McGrath
Surgery (Prelim), SUNY/Buffalo
Graduate Medical-Dental Education
Consortium
BUFFALO, Y;
Orthopaedic Surgery, SUNY/Buffalo
Graduate Med1cal-Dental Education
Consortium
BUFFALO, NY

Henry lee
Medicine (Prelim), McGaw Medical
Center-Northwest
CHICAGO, IL;
Ophthalmology, Wills Eye Hospital,
Thomas jefferson University
PHILADELPHIA, PA

Wayne Hwang
Medicine (Prelim), SU Y!Buffalo
Graduate Medical-Dental Education
Consortium,
BUFFALO, N Y;
Diagnostic Radiology, Allegheny
General Hospital
PITTSBURGH, PA

Amy jones
Internal Medicine, SUNY/Buffalo
Graduate Medical-Dental Education
Consortium
BUFFALO, Y

a

Michael Lipke
Surgery (Prelim), New York University
Medical Center
NEW YORK, NY

Won Hee Kim
Medicine/Pediatrics, Stony Brook
Teaching Hospital
$TONY BROOK, NY

Keith Herr
Psychiatry, Emory University School
of Medicine
ATLANTA, GA

B

Ellyn Sellers share in the excitmenl.

Edward Kim
Internal Medicine, SUNY/Buffalo
Graduate Medical-Dental Education
Consortium
BuFFALO, Y

Haruka ltakura
Internal Medicme, Hospital of the
University of Pennsylvania
PHILADELPHIA, PA

Group hug said it all this day for Keith
Herr, lisa Thebner and lisa Balduf.

Left to right: Sandra lee, Edward Kim and

Sanjiv Kayastha
Plastic Surgery, Spectrum HealthDowntown
GRAND RAPIDS, Ml

0

Karen lee
Pediatrics, University of Massachusetts
WORCESTER, MA

Carri·Ann Megargel
Internal Medicine, SU Y!Buffalo
Graduate Medical- Dental Educauon
Consortium
BUFFALO, NY

Sandra lee
Psychiatry, YP Hospital-Cornell
NEw YoRK, NY

Michael Melman
Research

Tingting Li
Internal Medicine,
Barnes-jeWISh Hospital
ST LOUIS, MO

Daniele Merlis
Pediatrics, Albert Einstein College of
Medicine, jacobi Medical Center
BRONX, NY

Michael Lioudis
Graduate School MBA, Umversity of
orth Carolina
CHAPEL HILL, C

Susan Miller
Pediatrics, SU Y!Buffalo Graduate
Medical-Dental Education
Consortium
BUFFALO, NY

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�··· · ···· · ····· ·· · ·· ············· · ··················· · ············ •

· ·.

~
I

Charles Roche
Medicine (Prelim), SUNY/Buffalo
Graduate Medical-Dental Educauon
Consortium
BUFFALO, NY;
Diagnostic Radiology, SUNY/Buffalo
Graduate Medical-Dental Education
Consortium
BUFFALO, NY

Charlie Pan
Medicine (Prelim), St. joseph Mercy
Hospital
ANN ARBOR, Ml;
Radiation Oncology, University of
Michigan Hospitals
ANN ARBOR, Ml
Kathryn Montgomery
Pediatrics, University of Connecticut
FARMINGTON, CT

Natesh Parashurama
Surgery (Prelim), Boston Universtty
BosTON, MA

Amy Morrow
Pediatrics, University of Michigan
Hospitals
ANN ARBOR, Ml

Parag Parikh
Surgery (Prelim), University of
California, Irvine Medical Center,
IRVINE, CA;
Otolaryngology, University of
California, Irvine Medical Center
IRVI NE, CA

Khader Muqtadir
Medicine (Prelim), Evanston NW
Health Care
EVANSTON, IL;
Diagnostic Radiology, Cleveland Clinic
CLEVELA~D. OH

Zulma Rosado
Family Practice, Jamaica Hospital
Medical Center
jAMAI CA, NY
Ari Rubenfeld
Surgery (Preitm), Georgetown
University, WASHINGTON, DC;
Otolaryngology, Georgetown
University
WA SHI GTON, DC

Rupal Patel
Transitional, Crozer-Chester Medical,
SPRINGFIELD, PA ; Ophthalmology,
SU Y/Buffalo Graduate MedicalDental Education Consortium
BUFFALO, NY

Elena Napolitano
Medicine (Prelim), SUNY/Buffalo
Graduate Medical-Dental Education
Consortium
BUFFALO, Y;
Physical Medicine and
Rehabiiitation,UMDNJ
EWARK, j

Frank Salamone
Otolaryngology, Umverstty of
Cincinnati
CINCINNATI, OH
Ahlam Saleh
Family Practice, University of
Massachusetts Medical Center Health
Alliance Hospital-Leominster
FITCHBURG, MA

David Pawlowski
Family Practice, Duke University
Medical Center
DURHAM, NC
Daniel Perregaux
Emergency Medicine, Mancopa
Medical Center
PHOENIX, AZ

Heidi Narins
Emergency Medicine, SUNY/Buffalo
Graduate Medical-Dental Educauon
Consortium
BUFFALO, Y

Anthony Santilli
Internal Medicine, Brown University
PROVIDENCE, Rl
Marsilia Seiwell
Obstetrics/Gynecology, SUNY/Buffalo
Graduate Medtcai-Dental Education
Consortium
BuFFALO, NY

Stephen Przynosch
Family Practice, Toledo Hospital
TOLEDO, OH

Jeffrey Nechleba
Orthopaedics, Hamot Medical Center
ERIE, PA

Mary Rose Puthiyamadam
Medicine/Pediatrics, Penn State
Geisinger
HERSHEY, PA

Bretton Newman
Family Practice, Columbta St. Marks
SALT LAKE CnY, UT

Ellyn Sellers
Famtiy Practice, Catilion Health Systems
ROANOKE, VA

Crystal Nicholson -Springer
Pediatrics, Nassau County Medical
Center
EAST MEADOW, NY

Michael Rauh
Surgery, SUNY/Buffalo Graduate
Medical-Dental Educauon
Consortium
BUFFALO, Y

Daniel Nosek
Family Practice, Palmetto Richland
Memorial Hospital
CoLuMBIA, SC

James Reuther
Psychiatry, University of Texas
Medical School
HousToN, TX

Joy Nwachukwu
internal Medicine, SUNY/Buffalo
Graduate Medical-Dental Education
Consortium
BUFFALO, NY

Kevin Robillard
Internal Medicine, University of
Rochester/Strong Memorial Hospital
ROCHESTER, Y

Sonia Shah
Internal Medicine, Medical College of
Vtrgmia
Richmond , VA
Shams Sheikh
Medicine (Prelim), University of
Rochester/Strong Memorial Hospital,
Roc HESTER, Y;
Diagnostic Radiology, Yale-New Haven
Hospttal
NEW HAVEN, CT
Gregory Shipkey
Emergency Medicine, Darnal Army
Community Hospital
FoRT HooD, TX

Michael O' Brien
Internal Medicine, Brown University
PROVIDENCE, Rl

Natalie Sikka
Pediatrics, Baylor College Medical
HousTON, TX

Thomas O'Donnell
Otolaryngology, Penn State Geisinger
DANVILLE, PA

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Jenny Speranza
Surgery, Stony Brook Teachers Hosptta!
STONY BROOK, y
Brian Stout
Pediatrics, Umversity Hospttals
CLEVELAND, OH
Michael Stratemeier
Emergency Medicine, orth Shore
Umverstty
MANHASSETT, NY
Ivan larkin
Surgery (Prelim), Monmouth Medical
Center
LONG BRA NCH, j
lisa Thebner
Pediatrics, Emstein!Montefiore
BRONX, NY
Eric Thierman
Medicine/Pediatrics, SU Y/Buffalo
Graduate Medical-Dental Education
Consortium
BUFFALO, NY
Katherine Timoszyk
Medicine (Prelim), Georgetown
University Hospital, WASH I GTON, DC;
Neurology, Duke University
DuRHAM , NC
Racquet Tonuzi
Medictne!Pediatrics, SUNY/Buffalo
Graduate Medtcai-Dental Educauon
Consortium
BUFFALO, NY
Sylvia Tufano
Obstetrics/Gynecology, Untversity of
Connecticut
FARMINGTON, CT
Jayadeep Varanasi
Internal Medicine, University of orth
Carohna Hospital
CHAPEL Ht LL, NC
Leonard Vaughan
Surgery (Prelim), SUNY/Buffalo
Graduate Medical-Dental Education
Consortium
BUFFALO, NY
Amy Weinstein
Internal Medicine, McGaw Medical
Center-Northwest
CHICAGO, IL
Ryan White
Urology, Albany Medical Center
Hospttal
ALBANY, NY
Judi Wolf
Pedtatncs, SUNY/Buffalo Graduate
Medical-Dental Education
Consortium
BUFFALO, NY

�Mission Improbable
SUZANNA GOODYEAR ,

'Z"

\

'90,

ENTERED US' S MEDICAL SCHOOL AT AGE 54

GooDYfi\R \V\S BOR"&lt;

atatimewhenprofessionalcareeroptionsforwomenwerefew

and generally considered little more than stopgaps until marriage and children came along.
Small wonder, then, that she nearly missed out on fulfilling her girlhood dream of becoming
a physician and caring for the poor and needy "It's something that's been in my blood all my life,"
she says. "My uncle was the medical director of a Quaker mission in Kenya in the 1930s, and it was
something I knew I wanted to do. But I didn't know how to get there and I didn't know who to ask."
From the age of 14 through her teens, of a pharmaceutical company. A couple
Goodyear held tightly to her goal. lt of years later, after taking a position in
wasn't until her college years that her the Biochemistry Department at Albany
dreambegantofade.Shehadstartedout Medical College in Albany, ew York,
as a chemistry major and pre- r - - - - - - - - . she again thought briefly
8 v
med student at Earlham
about applying for medical
8 E T 5 v
College in Richmond ,
school. But self-doubt won
5 A w v E R
out, and she allowed her
Indiana, but there were no
dream to return to dormancy.
strong female role models
after whom she could pattern her
As the years passed, she immersed
career. It was the 1950s, and women herself in her chemistry pursuits. While
physicians-especially women in on staff at the New York State Departprivate practice-were not common.
ment of Health in Albany, she was honWhile at Earlham , she had an ored in the 1966 edition of Outstanding
opportunity to work with a few women Young Women ofAmerica for her work in
physicians in the wards of a psychiatric measuring radioactive fallout. Nine years
hospital. However, instead of spurring later, she became one of the department's
her on, the experience only served to senior radiologic chemists.
discourage her.
As rewarding as Goodyear's career
'These women were my mother's appeared, deep down she still wasn't
generation, and I was not impressed. satisfied . Despite her success-and
They were subordinate to the men . imperceptibly to everyone, including
Where the men were surgeons, the herself-the seeds of her dream had
women took care of coughs and colds. continued to send forth roots. Doubts
As I look back today, I admire them, but about the career path she'd chosen
l didn't then. l was 21 and l didn't see increased in the 1970s as she met and
them as pioneers," she says.
began socializing with several women
"l think if l'd had a mentor , l might physicians. Unlike those she'd known
have gone on. But there was no one to in college, these women were enjoying
show me the way, sol gave up. "
successful medical careers.
After completing a master of science
Around that time, circumstances at
degree in biochemistry in 1957, she work began to shift, as well. There were
went to work in the research laboratory cutbacks and frustrations at the lab,

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including increasing problems with
the computers . Annoyed with the
programmers' inability to correct the
problems, Goodyear took a 10-week
math application course and began to
do some programming on her own.
"I also took a course in statistics
because the department was reducing
staff and l realized these were good
skills to have," she says. "But l didn't
enjoy it that much , and l knew l didn't
want to do it for the rest of my life. l'd
work on the computers for an hour or so
a day and then head back up to the lab to
do something else. That's when l finally
sat down and asked myself, 'What would
l do ifl could do anything in the world?"'
The answer hit her square in the
heart: lt was 1983, Goodyear was 52,
and she knew she still wanted to be a
doctor. "l sat down and cried," she says.
Then she set out to change her life.

BAcK To ScHooL AT 54
t first, Goodyear was secretive about
her decision to apply to medical
school. "lt was very difficult to find
anybody l felt l could confide in. l
didn't need the entire health department lab putting me down. So l'd sneak
into the library to get information on
medical school and costs. "

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�Today Suzanna Goodyear, MD '90, works for Health Access, a free clinic in rural Clarksburg, West Virginia, where she serves indigent and low-income patients_

One of her surreptitious factgathering efforts netted the study guide
for the Medical College Admission Test
(MCAT). At the back ofthe booklet she
found the information she needed on
the application process.
"I saw that I needed to do some
review work to prepare," she says.
"After all, I'd been out of school for
more than 30 years. So I started taking
courses at Russell Sage College in Troy,
New York, and reading textbooks on my
own during my lunch hour. "
Continuing to work full-time in the

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lab, Goodyear spent the next two years
studying genetics, organic chemistry,
biology and physics. To broaden her
experience, she also worked as a volunteer with geriatric patients. She passed the
Red Cross Water Safety course and taught
swimming lessons. Next, she completed
coursesinFirstAidandcardiopulmonary
resuscitation and joined an emergency
ambulance crew. After being on call every
Friday and Saturday night for two years,
she completed tests to become a licensed
emergency medical technician.
The preparation paid off and, at

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age 54, she passed the MCAT. But
scoring well on the test was just one
hurdle on the way to gaining acceptance
to medical school. She then had to convince an admissions commiHee that she
was a good investment, despite being
older than most other applicants.
"Once I knew what I wanted,
assuring other people that I could do it
became my greatest barrier to medical
school," she says.
While interviewing at UB's School of
Medicine and Biomedical Sciences, she
readilyconcededthatshewasolderthan

�the typical student and then pointed out
the advantages. "I told them, 'Statistically I may have less time, but you don't
really know that about anyone. The
average age for a doctor to commit
suicide is 45, and I'm past that. I have
no children, and I'm past that. I have
many years to devote to medicine."'
Thomas Guttuso, MD, director of
admissions at UB's School of Medicine
and Biomedical Sciences, says that
although the school does not have an
official age policy, Goodyear's application "did raise eyebrows."
"In the case of an older student,
concerns arise about the appropriateness of spending the money it takes to
educate a medical student versus what
society will get back," he says.
"However, we judged Goodyear's
application like everyone else's, on
the suitability of her qualifications. "
Recalling his interview with her,
Guttuso says, "She was very energetic
and we felt she would give back to
society what she gained from a medical education. And her career certainly
bears this out."
In April 1986, Goodyear received
notice of her acceptance by UB. Her
next step was to retire from her job,
which, at the time, involved monitoring airborne radioactivity from the
Chernobyl disaster. She was ready to
become a full-time medical student.
AGE G~P

A

ge has its advantages, Goodyear
realized, as she discovered that she
was better off financially than many
of her fellow students.
''I'd had a good job with the State of
New York, and I was eligible for early
retirement at half my state salary. I didn't
have to scrimp, like so many of my
classmates did. Also , I had never
married and had no children and my
parents had died a few years earlier, so I
didn't have family responsibilities. I was
entirely free to go my own way."

On the other hand, after 30 years in services. In her third year of residency at
the professional world, Goodyear had the local hospital, she worked at the
developed certain expectations of her clinic several evenings a week.
peers. "It irked me when classes started
"One night when I was finished with
late because people couldn't get up in my shift, I was talking to one of the
the morning and be there on time. I felt founding physicians. My excitement
the same way as an intern and resident. about the program must have shown
I expected things to start on time and for through, because they found the money
people to pull their own load. I may to pay me as a full-time staff member.
have been slower, but I worked hard so I started in August 1993, following
people wouldn't have to do my work." graduation and completion of my
Goodyear's social life was affected by family practice boards in july."
Today, Goodyear continues at Health
the age gap, as well. "My interests were
different, and I didn't know how to Access, which is one of about a dozen
socialize with my peers," she says. "I free clinics in the state. Supported by
attended the Methodist church near cam- state and community funding, the clinic
pus. It was an older congregation in what serves patients who meet federal stanhad been a working-class neighborhood. dards for poverty, have no insurance, are
not eligible for Medicaid and have no
That's where I got my best support."
Another problem, Goodyear says, was other source of assistance. West Virginia
her inability to stay awake between limits Medicaid to pregnant women,
1 and 3 p.m. "I could study all morning disabled persons and children under age
and all evening, but not in the after- 18, leaving a large population of patients
noon," she says. "When I went back to eligible for the clinic's assistance.
"One of the reasons we use such
school, I had no trouble with nightschool work. But afternoon lectures were strict guidelines is so we can access
indigent patient programs," she says.
dreadful. They still are!"
"At this level, the hospital provides 100percent assistance to our patients, and
MISSIO'\ TO THE NfED)
uring her senior year in medical many major drug companies offer
school, Goodyear had an opportu- special pharmacy assistance programs."
Health Access provides primary care,
nity to experience the mission field.
She spent eight weeks at the Presby- as well as referrals to specialties, through
terian Mission Hospital in Kikuyu, the volunteer service of medical staff in
Kenya. It was rewarding, but enough of the community. All of Clarksburg's phya culture shock to prompt her to seek sicians are on the local hospital staff,
charitable opportunities closer to home. and about 90 percent of them donate
After her return to the States, she time to the clinic. Additionally, a pharfocused on serving impoverished maceutical company in the area donates
many of the products the clinic needs.
patients in rural America.
For Goodyear, "working part-time
"I was fascinated by an article written
by a doctor who'd set up a clinic in for the pittance that a charitable healthAppalachia, and I wanted to do some- care organization can pay" represents
thing similar. That's why I came to the apex of her career and fulfillment of
Clarksburg, West Virginia, for my a lifelong dream.
residency," she says.
"Caring for people who really need it
When a new community clinic for is the most rewarding thing I've ever
indigent and low-income patients done," she says. "And to think I almost
opened in Clarksburg in October 1992, missed it. Sometimes the highly
Goodyear was quick to volunteer her improbable is possible, after all." +

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A K E R

Empowerment
· and WomenS

Health

EQUAL OPPORTUNITY
FOR A LONG,
FULFILLING LIFE

Betty Friedan,

the first president of the National Organization for
Women and the nation's best-known feminist, presented an informal talk on the
impact of women's empowerment on their physical and mental health on
May 1, 1999, during the 62nd Spring Clinical Day sponsored by the UB Medical
Alumni Association, held in the Buffalo-Niagara Marriott in Amherst, New York.
clearly brought about this
Friedan was the first
change, Friedan noted,
woman to present the Stockpointing out that this
ton Kimball lecture and to
change has an important
receive the association's
impact on women's health,
Stockton Kimball Award.
as well as on their econoWomen's health was the
mic status.
theme of this year's Spring
She referred to an early
Clinical Day, which featured
study that found that
several presentations on
women's mental health
breast and ovarian cancer.
peaked when they were in
Accustomed to speaking
their 20s and dropped
before gatherings attended
dramatically after age 40,
almost exclusively by
compared to men. "It was
women, Friedan opened her
thought normal for
remarks by joking about the
women
to go into depresnumber of men in the audision
in
menopause,"
ence, a legacy of a profesFriedan said.
sion that for many years was Author and feminist Betty Friedon.
"It even had a classifialmost exclusively male. She
cation: involutional melancholia."
contrasted that historical state of affairs with
When women were defined only by their
the current situation, in which enrollments in
feminine
role, not as individuals in their own
many medical schools are half women. In fact,
right,
life
was over after 40, she noted. "The
the class entering the UB School of Medicine
love
story
was the only one that women could
and Biomedical Sciences this fall will have a
be a hero of. But now, women's mental health
majority of women for the first time in the
after menopause is better, maybe better even
school's 153-year history.
than it was in their 20s, 30s and 40s. "
The empowerment of women through the
women's movement of the 1960s and '70s

Buffalo

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�As women en tered the professions in
large num bers, the con cept of the
working woman took on a negative
tone, Friedan observed. "The hype was
'Women have to have it all,"' she said.
"But nobody ever says anything about
men having it alL For 30 years people
h ave been trying to prove that women's
employment is bad for children and
they couldn' t do it. Now the newest
study sh ows that employment is good
for children . .. . Big news! "
"Of course women are happier when
they aren't living exclusively through
their children and they aren't seething
with frustrated rage," Friedan said.
"There is also less stress and pressure on
the man when he isn't solely responsible
for providing for the family. That has to
be good for children."
Friedan said that, while empowerment has had a positive effect on women,
th ey historically have lived longer than
men, and she suggested this discrepancy as a fertile area for study. "Something about the male role must be a
killer. There should be research into the
things about women's roles that are good
for life," she said, going on to state what
she thinks some of those might be.
"We carry with us a biological
grou nding in a sensitivity to life,"
Friedan said . "It is part of the socialization of women. We don' t have to
suppress our tears and fears. "
She offered three characteristics that
women who are vital into their 90s have
in common: the ability to deal with
change, th e ability to deal with loss and
the willingness to take risks.

Medical Alumni Lifetime
Achievement Awards
his year's recipients of the School of Medicine
and Biomedical Sciences' lifetime Medical
Alumni Achievement Awards are as follow:
• Elizabeth Olmsted Ross, MD '39,
clinical assistant professor of ophthalmology
at UBwho has been in private practice in
Buffalo since 1944. (See profile on page 39.}

then went on to complete fellowships in gastrointestinal
physiology at the university's Cardiovascular Research
Institute and at the Veterans Administration HospitaL
Throughout his career, Way has been recognized for his
excellence in teaching and has received numerous
commendations and citations for his contributions in
this area. From 1991-1992, he was president of the
Son Francisco Surgical Society and from 1995-1997,
served as chair of the board of trustees lor the Society
lor Surgery of the Alimentary Tract. Currently, he is a
consultant to the Gastroenterology and Urology Devices Advisory Panel for the FDA.

• James E. Youker, MD '54,
professor and chair of the Department
• Stephen C. Scheiber, MD '64,
of Radiology at the Medical College of
is professor of psychiatry at NorthwestWisconsin. In recognition of the excelern University and executive vice presilence Youker has brought to his departdent lor the American Board of Psychiament-especially in the areas of patry and Neurology, a position he has
tient care and research-he was given
held lor 10 years. "However, to all of
the Distinguished Service Award by the
us-more than anyone else inthe United
Medical College of Wisconsin in 1989.1n
States-he is someone who is seen as
1997, he was a recipient of a Gold
the standard bearer for American psyMedal of the Association of University
chiatry and neurology," said Susan
Radiologists. Youker has served as a
Mcleer, chair of UB's Department of
member of the Board of Chancellors
Psychiatry, who introduced Scheiber. She
and as vice president lor the American
added that Scheiber has built a national
College of Radiology. He has also served
reputation as an educator and scholar
STEPHEN c. SCHEIBER, MD
on the board of trustees for the Radioconcerned with the health of physicians
logical Society of North America. Currently, he is a and the educational process in psychiatry. "But, most
member of the executive committee of the American importantly," she said, "Steve has worked tirelessly
Board of Medical Specialties and is president-elect of to ensure that residents in psychiatry and neurology
the ABMS.
access quality training" and noted that his work with
• Lawrence W. Way, MD '59, vice chair ofthe the American Boord helps to assure that patients have
Department of Surgery at the University of California access to well-trained and skilled professionals."
at San Francisco and director of UCSF's Videoscopic Scheiber has served on the editorial boards of numerCenter in the Department of Surgery. Anative of St. ous peer-reviewed journals, has been a reviewer lor
Louis, Missouri, Way attended Cornell University be- NIMH grants and has been honored as a visiting guest
lore earning his medical degree at UB. He completed professor at over 50 medical schools throughout the
his internship and residency training at UCSF, where he nation.

New Alumni Association Otficers Elected

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�Clinical]

Madeline and Frederick Szymanski, Closs of 1939, enjoying 60-yeor reunion festivities.

Elizabeth Olmsted Ross and John H.
Remington, celebrating 60-yeor reunion.

Elizabeth Moher, Closs of 1983, with Betty Friedon, this
year's recipient of the Stockton Kimball Award.

Robert Harvey,
Closs of 1950, leh,
accepting this
year's attendance
trophy, which was
presented by
Richard Collins,
Closs of 1983,
incoming president
of the Medical
Alumni
Association.

Cathy and John Montroy, Closs of 1938, relaxing at dinner.

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�first row: Frederick]. Szymanski; second row, left to
right: Anthony V. Postoloff, Frank T. Riforgiato, john
F. Montroy, john). Squadrito, john H. Remington,
Elizabeth Pierce Olmsted Ross, Roy E. Seibel, Sr.

first row, left to right: jacqueline Paroski, judith
Weinstein, julia Cullen; second row, left to right: john
Egan, George Erickson, john Sharp, Robert Harvey,
Frank Pfalzer, Bradley Aust, Robert Smith, Robert
Sanford, Charles Bathrick, Lawrence Carden, Henry
Thiede, Irving Lang, Philip Dennen, Richard
Schwartz, Paul Buerger, Max Schneider,
Pierce Weinstein.

first row, left to right: John Kutrybala, Clay
Burchell, Sylvia Griva Lizlovs, Allen Lesswing,
Donald Wilson; second row, left to right: William
Howard, james Youker, Robert Miller, john
Conboy, Robert Pletman, Louis Cloutier, Donald
Murray, Malcolm Leslie, Robert Oshrin, Edward
Wenzlaff, Edward Rayhill, Edward Bockstahler,
Richard Mayer, Nicholas Carosella, jack Lemann.

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�CLASS

REUNIONS

First row, left to right: Max Doubrava, john
McMahon, Daniel Kozera, joseph Monte, David
Denzel, Donn Yacht, Sandra Wiltse, William Mangan,
George Baeumler, Constantine Cretekos,
Charles Anderson, Eli Isaacs.

First row, left to right: William Fleming, Frederick
Painton, Leo Michalek, Walter Hoffman, Irving
Sterman, Elizabeth Serrage, Stephen Scheiber, David
Weinstein, james Tibbetts, David Ziegler.

First row, left to right: Penny Gardner, Thomas
Scanlon, Moira Burke, Mona Milstein, Evelyn
Roisman, David Arkin, Hachiro Nakamura, Daniel
Levin, Dorothea Downey, Madeline White; second

row, left to right: Timothy Harrington, David
Schreiber, Michael Pisick, Hanley Horwitz,
William Major, Marion Wind, Robert Hartog,
james White, james Cavalieri, Gerald Stinziano,
David Sherer.

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�• · · · · · · · · · · · · · · · · · · · · · · · · · · · · · · · · · · · · · · · · · · · · · ···········································

first row, left to right: Anna G. Engel, Sandford
Pleskow, Leslie Ford, Thomas Chmielewski, Gordon
Avery, Daniel Morelli; second row, left to right: Louise
Stomierowski, Bruce Thiers, Daniel Lasser, Hing-Har
Lo, Diane Matuszak, Virginia Sybert, Thomas
Varecka; third row, left to right: Bruce Middendorf,
Richard Buckley, Alan Burstein, john Manzella,
jocular Ford, Lawrence Oufiero, james Smith; fourth

row, left to right: Paul Wierzbieniec, Roy Seibel,
james Pietraszek, Richard Hershcopf, james Budny.

First row, left to right: Bruce aughton, Robin
Adair, Walter Balon; second row, left to right:
Frederick Eames, Richard Irene, Arthur Rosiello,
joseph Buran; third row, left to right: john Crofts,
john Canty, Peter Shields, Frank Schreck, Charles
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REUNIONS

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row, left to right: Eric Southard, Paul Lecat, Mark
Pundt, Christopher Bartolone, Geoffrey Seidel,
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~

Tomorrow's Physicians
Confront Choice
BY

UL

\1.

rt:'

STACEY

r nuo r

~A

BLYTH

on the morning of

October 24, 1998, I had no idea how that one call
and the events precipitating it would change my
experience as a second-year medical student.
When I answered the phone, my classmate asked,
"Have you heard?"
"About what?" I responded.
She proceeded to tell me about the
murder of Dr. Barnett Slepian. As she
spelled out the details , I went a little
numb. Despite being safely at home
with my husband and daughter, my
sense of security was altered. A bullet
shattered a window, a man's flesh, and
his family's future.
That same bullet instilled in me a
sense of urgency and a need to evaluate
my changing role in the abortion
debate. Since that October day I have
begun to read about the subject and
discuss it with the people around me for
the first time. What follows is just some
of what I've learned and pondered
during these past months.
Abortion is a part of human history.
Legal or illegal, it has always occurred;
legality simply increases its safety and
decreases the rates. Maternal mortality
and loss of fertility increase exponentially when abortion is illegal, and abortion rates are highest in countries where
the procedure is illegal (for instance,
Peru's rate is 52 procedures per 1,000
women). That's not to say that our rate
in the United States-23 procedures per
1,000-could not be significantly lower.

®

Stacey Blyth, a third-year medical student at the University at Buffalo
School of Medicine and Biomedical Sciences, is co-coordinator of the local
chapter of Medical Students for Choice. MSFC National has over 4,000
student members and assists BO active chapters across the country.

just compare that to a
rate of 6 procedures per
1,000 women in the
etherlands, which has a long history of
safe, legal access in combination with
reality-based sex education and widely
available birth control. This information
made me wonder why we are still having
this discussion. Whether abortion is
legal or illegal, abortion rates will never
reach zero due to the imperfect nature of
birth control, cases of medical necessity
and, more importantly, the imperfection
of humanity; however, we could significantly reduce the rates by providing our
patients with better options.
According to current statistics, 4 3
percent of the women in the U.S. will
have an abortion by age 45. Most women
who choose to terminate a pregnancy
do so only once. Only one unmanageable pregnancy in a reproductive lifetime of roughly 30 years is really quite
remarkable. These patients are typically
young, and two-thirds plan to have
children in the future . They come from
every conceivable racial, ethnic, socioeconomic and religious background.
During the first year of medical school,
we talked a lot about our future role as
physicians. We were helped to understand that to be good physicians, we

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would need to provide nonjudgmental
care to many patients who made life
choices with which we were not personally comfortable, such as smoking. Our
job will not be to judge our patients'
actions and then provide care if we deem
them worthy. Yet nowhere in our discussions was any mention made of a woman's
right to a safe, legal medical procedure
(even if we might not make the same
choices for ourselves). When physicians
provide care, they are performing important services that save and improve lives;
it has nothing to do with validating their
patients' actions or lifestyles.
To provide high-quality health care
over a lifetime, I must forever search my
soul for empathy, tolerance and a basic
regard for humanity. The rhetoric surrounding abortion is being manipulated
to increase intolerance in our culture
and drive people to hate. A disturbing
trend that is not well understood unless
you really pursue it is the growing alliances between extremist hate groups of
all sorts and some extremist groups in
the anti-abortion movement that advocate violence. During the past 10 years
these groups have participated in an

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�............. . ........................... .. ............. . ............ . ............. . .

increasingly violent campaign to shut remove the pro-choice bumper sticker been able to move beyond abortion to
down abortion clinics and, as a result, from our truck because she was afraid talk about larger public-health and
the number of providers has been the bad people would blow it up. The reproductive-health issues. We are strugsteadily decreasing. Currently, 84 per- idea that I have to choose between being gling to understand how our education
cent of the counties in this country do a good doctor and protecting my child and future practice habits can positively
not have a single abortion provider, and from the infectious hatred of these people (or negatively) influence our society's
roughly 60 percent of the remaining is a constant source of conflict for me. collective well-being. As future physiThe American Medical Association's cians, we are challenging ourselves to
providers are at or past retirement age.
So what do we do when these brave official position is that the decision of confront intolerance. Given the priviolder physicians retire? These men and whether or not to terminate a pregnancy leged place we will assume in this
women remember the carnage and abuse is a private matter between a woman society, it is my belief that we must hold
that women suffered as a result of illegal and her physician. This position works ourselves to the highest of standards.
abortion; however, the physicians who on paper, but if our current abortion We must find a way to embrace humanhave trained since 1973 do not have this providers are approaching retirement ity in all of its imperfections if we are to
horrible experience to help them and we are not training our future establish the trust necessary to provide
understand the massive public-health physicians in all aspects of reproductive quality care to our patients.
As the anti-abortion movement has
imperative of safe, legal access. How services, who will have the skills necesbecome
more violent, it has also become
can we ask young physicians, just sary to help women make difficult
smaller and more
out of school
rna rgi na lized.
and with otherwise
I
The fear its mempromising futures,
TO PROVIDE HIGH-QUALITY HEALTH CARE OVER A LIFETIME,
bers instill in us
to take on this
MUST FOREVER SEARCH MY SOUL FOR EMPATHY, TOLERANCE
is real, but the
work alone?
AND A BASIC REGARD FOR HUMANITY . THE RHETORIC
danger our mediJust when I begin
cal ins ti tu tions
to make my peace
SURROUNDING ABORTION IS BEING MANIPULATED TO INCREASE
and
practitioners
with my own loss
INTOLERANCE
IN
OUR
CULTURE
AND
DRIVE
PEOPLE
TO
HATE
.
will
face if they
of personal safety,
expand student
Dr. Slepian's words
education and
come back to haunt
me. He spoke with Medical Students for choices? More than 90 percent of abor- patient services is, in actuality, extremely
Choice last year about his training in a tions are currently being performed limited. Terrorism should never be a
less volatile time and of his desire to outside of hospitals, yet most medical factor in determining which medical
decrease his workload. Unfortunately, students and residents still train in hospi- procedures are available to our patients.
The precedent that will be set if the
because younger students were not tals. This must be remedied if students
anti-choice
movement is successful
being trained, he felt he could not aban- are to get real exposure to a vital medical
don the disadvantaged population to procedure and gain appreciation for how should frighten all of us, regardless of
whom he provided care. But what really essential abortion services are for many the choices we might make in our pergot to me was his description ofhow anti- women and families. Unless we find a sonal lives. I for one refuse to let my
choice protesters would picket his home way to include abortion training in the morality and future practice habits be
and stalk his children. They would standard medical education, it can be dictated to me by an angry minority
with guns. I will continue to believe in a
accost them at school and at the grocery marginalized and limited by terrorists.
here's
the
surprise
ending:
So
world where we can draw upon the
store with violent, threatening rhetoric
Despite the bleak tone of most of this diversity of the human community to
about their father.
My daughter, who will turn eight article, I remain stubbornly optimistic. gain strength, not create fear. +
soon, has little more to worry about Faculty support and involvement in
right now than what color butterfly clips student efforts to learn about this issue Sources for 111formalion,n tins article incluclr
she should wear in her hair, but she have been encouraging. As we've The Alan Guumachcr lnstltuu· c~~ IHL
notices things. Even though we have discussed abortion provision, we've agr-usa org) ,\tcdical Students for C.ho1ce
tried to shelter her from this violence, come to a much better understanding of www.ms4c.ot g, and the SoutiH'tll Po' crt\
she recently asked my husband to the complexity of this issue. We've even Lcm Center (Win~ Sf1lccnter org).
---

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L I N D A

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C 0 R DE R ,

PH

D,

C F R

E

AWord from the Dtrector of Development
"
development program, over time, is the growth of its endowment. Yet, in
the cycle of academic seasons, we have spent very little
time discussing this aspect of support for the school.
just what is so important about endowment?
Endowment is an institution's land,
buildings and invested capital resources. In the arena of
public higher education, most of the former-land and buildings-are maintained by the state. The latter generates funds
to be used, in perpetuity, to support designated programs.
One ofUB's earliest endowed funds was a gift from Devillo W.
Harrington, who was injured during the Civil War. He was
brought to Buffalo, where interns from
UB treated his wounds. He recovered,
remained in Buffalo, and decided to go
to medical school, graduating in 1871.
In honor of his twenty-fifth anniversary of graduation, in 1896, he established an endowment. For over a
century, the Harrington Lectureship
has brought outstanding medical
sci en tis ts to
Buffalo. Since
The endowment is, in a very real sense, the
then, many
school's security for its future.
others have
contributed to
the school's overall endowment to provide permanent
support for designated programs they believe are important
to the quality of the academic experience. The endowment is,
in a very real sense, the school's security for its future.
The school has a variety of
funding sources, of which the state's share is relatively small,
approximately 12.7 percent. The school's clinical practice
plan provides the largest single source of income, while
research grants and contracts, annual gifts and endowment
gifts comprise small- but significant and increasing-sources
of income. Endowment income provides perpetual funding
for either the general unrestricted use by the dean (extremely
important) or for specified programs established in accordance with the terms of the endowment gift. Endowment
income provides a hedge against downturns in the economy;
fluctuations in the political climate; variations in the numbers

®

Buffalo

of alumni and friends supporting the school's annual appeal
and other changes in our academic environment. Today's
students and faculty benefit from past endowment gifts, while
tomorrow's school is being created by today's gifts.
I (
'&gt;
Additional endowment gifts
are the surest way to grow the school's endowment and to
protect its mission and vision. Endowment also grows through
prudent investment of endowment resources for the long
term. A balanced fund, consisting of high-quality, readily
marketable stocks, bonds and other assets, is important to
meet the goals of growth to outpace inflation and to provide
a steady income stream that supports the programs
designated by endowment agreements. Several investment
advisors, overseen by UB Foundation's (UBF) Investment
Committee, manage the school's endowment, and a similar
committee oversees the school's state-held endowment. The
investment objective is to maximize total return-dividends
plus market value-within reasonable risk parameters.
Each year the endowment disburses an income stream for
current use in accordance with each fund's stated purpose.
The percentage disbursed varies slightly between state-held
and UBF-held endowments. Generally, between 4 percent
and 6 percent of the total endowment's average market value,
calculated over the previous three to five years, is made
available for spending. The rest of the total return is retained
with the endowment principal to secure and even increase its
future buying power.
The market value of the
school'sendowmentassetswas$l32,l61,604,asof]une30, 1998.
A year prior, this amount was $111,265,374. Five years ago, in
1993, the school's combined endowment stood at $69,398, 610.
The 1998 total represents an increase of over 90 percent in
value since 1993. Within the next five years, I trust the
endowment will "beat its own record" and at least double in
value. This will require many new, significant endowment
gifts, in addition to the ongoing wise management of the funds
already in the care of the State University and UBF.
Watch for additional information about endowments in a
future issue of Buffalo Physician. In the interim, if you would
like information about initiating a named endowed fund, or
have any questions, please contact me by phone, toll free, at
1 (877) 826-3246; or by e-mail at ljcorder@buffalo.edu.

Physician

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�Dear Fellow Alumni,
As THE E'W PRESIDE T OF THE MEDICAL ALGM I AssociA TIO!\ , I plan
to continue the good work started by our previous presidents. Thanks to the
leadership and direction from our past president, Elizabeth Maher, and the hard
work of Patricia Duffner, this year's Spring Clinical Day, titled "Women's Health,"
was a tremendous success. The lecture by this year's Stockton Kimball lecturer, Betty
Friedan, was interesting, insightful and humorous. Already, plans are
under way for next year's event.
The Physician- Student Mentoring Program is one of the more
tangible ways the Medical Alumni Association demonstrated its commitment to improving the experiences of the students this year. I would like
to take this opportunity to salute my medical school mentor as someone
who left a very positive mark on my medical career and to whom I am still
grateful. Dr. Clayton Peimer and I were paired up in August of 1979. I
remember asking Clay, "How in the world do you remember how to treat
something like congestive heart failure?" Clay, a hand surgeon, replied, "After you
treat something 500 times in medical school and residency, on the 501st time, it
begins to sink in." Clay, I have never forgotten that quote and I appreciate all that you
did for me and taught me during that period. I hope that I can leave as significant an
imprint on the students with whom I come in contact. This is the beauty of the
mentoring program. Please consider volunteering for the program by calling the
Medical Alumni Office at (716) 829-2778.
On August 9, 1999, the Medical Alumni Association will sponsor The White
Coat Ceremony at the Center for the Arts on the North Campus. At this ceremony,
the first-year students will be given their clinical white coats on the first day of their
orientation for medical school. We are proud to take part in this and sponsor such
a significant and meaningful event for the first-year students.
I look forward to the upcoming year and continued success for the Medical
Alumni Association.

R ich ar d L. C o ll ins , MD
President, Medical Alumni Association

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writes:
"I am a physician on the MediVan, a doctor's office on wheels
that gives care to the elderly
indigent. This is pro bono
publico activity
without
remuneration.
ANG E L O LAP I , MD '37 ,

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BERNARD H . SKLAR , MD '56 ,

writes: I retired November 1,
l99l, andam loving it. I saw Dave
Ben-Asher ['56] last winter in

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Tucson,AZ. He was looking good.
My E-mail address for the computer literate is bsklar l@idt.net.
Would love to hear from you.

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HARO L D BRODY, PHD , MD '61 ,

SUNY Distinguished Teaching
Professor in the Department of
Anatomy and Cell Biology at UB,
and his wife, Anne, received the
Lynn Millane Community Service Award from the Amherst
Senior Citizens Foundation,

hysician

NOTES

Inc., on April 23, 1999. The
award is presented to individuals who, through volunteer or
professional involvement, have
helped maintain and support
senior programs that provide
socialization, educational and
cultural activities, social support
and wellness. Anne Brody has
been especially dedicated to improving the quality of life for
senior citizens and has devoted
many years of work toward this
goal, according to Dr. Brody.

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R O NALD I. DOZO RETZ, MD '62,

was honored April 30, 1999, at
the UB Alumni Association's annual awards banquet, which recognizes individuals who have distinguished themselves in their
career or in their service to the
university. Dozoretz is founder,
president, chief executive officer
and chair of the board of FHC
Health Systems, the largest privately held company providing
behavioral health services in the
U. S. and Canada, and second

�•

·· · ·· · ··················· · · · ········ · ·· ·· · · ···· · ········ ·· ······························

I

largest mental-health managedcare company in the nation.

of Ophthalmology at Children's
Hospital of Pittsburgh. He is the
past president of the medical

clinical medicine at UB and a
frequent lecturer and consultant
with the Crohn's and Colitis

ROBERTA M . GILBERT , MD '62,

staff of the hospital and is president-elect for the American Association for Pediatric Ophthalmology and Strabismus. He also
serves as a reviewer for the jour-

Foundation of America.

writes: "I married joseph
Douglass in August 1998, author
of Red Cocaine
and a new book
on progress on
the fate of the
MIA-POWs. We
live in Falls
Church, VA. My
new book, Connecting with our
Children, will be out September
1999 (published by Wiley and
Sons). My first book, Extraordinary Relationships, has been in
print seven years and continues
to do well."

nal of Ophthalmology, American
journal of Ophthalmology, journal of the American Association
for Pediatric Ophthalmology and
Strabismus and has served on
the editorial board of Binocular
Vision.

1

received the Pennsylvania
Academy of Ophthalmology's
Distinguished Service Award on
March 19, 1999, in Pittsburgh.
He was honored by Pennsylvania's eye physicians and
surgeons for his
extraordinary
work and for
contributions to
the specialty of
ophthalmology.
Biglan is director

7

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was
honored at Springfest '99, the
Co u nty

Medical Center's
(ECMC) annual
black-tie dinner
dance, which was
held this year on
April24, 1999, at
the Hyatt Regency Buffalo. ovak
has been director ofECMC's gastroenterology unit since l980.In
addition, he attends in the
Hepatology Clinic and recently
developed an on-site GI consultative service at the Erie County
Home. He is also a professor of

B

was named to New York
Magazine's Uune 7, 1999) Best
Doctor "Hall of Fame." For
the last 20 years he has had a
private practice of orthopaedic
surgery in Manhattan, Y.

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MD '74,

begins a four-year term as a member of the board of directors of
the American Academy of
Dermatology (AAD). Thiers is
professor of dermatology at the
Medical University of South
Carolina. In addition, he holds
clinical appointments as attending physician at Medical University Hospital, Charleston, SC, and
chief of the Der-

has been named to the board of
directors of the American Acad-

BRUCE H . THIERS ,

matology Service
at Charleston Veterans Administra-

emy of Orthopaedic Surgeons and
the American Association of
Orthopaedic Surgeons. Toriello
is chief of the Department of
Orthopaedic Surgery at Wyckoff
Heights Medical Center in Brooklyn, Y, and attending orthopaedic surgeon at St. John's
Queens Hospital, Catholic Medical Center, Queens, NY. He also
currently serves on the board of
directors for the New York State

tion Medical Center. Thiers has

Orthopaedic Society and is a
delegate of the House of Del-

served the AAD in
many leadership positions, in-

egates for the Medical Society of
the State of ew York.

cludingassociateeditorofthejournal of the American Academy of
Dermatology. He has also served

Be sure to include your name and a phone number
or address where you can be reached.
Your fellow alum look forward to reading about
your storied past!

u

Experimental Dermatology, journal of the European Academy of
Dermatology and Venereology,
Current Opinion in Dermatology
and Clinical Dermatology.

EDWARD A . TOR IELL O , MD '80,

Here are some ways you can submit your story....
e·mail: bp-notes@buffalo.edu
fax:
716-645-2313
mail: Editor, Buffalo Physician,
136 Crofts Hall, Buffalo, NY 14260

a favorite memory, anecdote
or inspirational moment that you associate
with your medical education?
How about a favorite professor, mentor
or classmate you'd like to tell about?
Buffalo Physician is putting out a call
for stories about your past, which we will
publish in future issues of the magazine.

®

0

JAN M . NOVAK , MD '70,

Erie

ALBERT W . BIGL AN , MD '68,

9

JACOB D . ROZBRUCH , MD '73,

as editor of the Year Book of
Dermatology and Dermatologic
Surgery, consulting editor of
Dermatologic Clinics and as a
member of the editorial boards of

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hysician

KENNETH J . ROT H , MD '83,

writes: "Havingservedaschairman
of the Department of Internal
Medicine and vice chief of staff, I
will assume the role of chief of staff
at Sharp Memorial Hospital in San
Diego, CA, on january l, 2000.
Sharp Memorial Hospital is the flagship hospital for Sharp Healthcare,
which is the largest provider of
health care in San Diego County."
H E RB N E WTON , MD '84, writes:

"I just returned from participating in the 1999 Spring Clinical
Day lectures and the 15th

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. . . .

............ .... .

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reunion celebration for our class.
The lectures were excellent and
focused mainly on breast and
ovarian cancer. Although the
number of returning classmates
was modest, we had an excellent
time at the class reunion reception Friday night. Many of us
went out afterwards for chicken
wings and beer. On Saturday
night, the reception dinner was
held at the Dakota Grill, which
turned out to be an excellent
venue. The dinner and service
were outstanding. We all had a
great time getting reacquainted
and caught up on our careers and
families. The dinner was organized by Dave and jill Pfalzer,
both of whom should be congratulated for all the hard work
they put into this great event!
From all of us who participated
in the dinner reception , l would
like to offer a toast to Dave and
jill. Thanks guys!!

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CHRISTOPHER

'91 , has

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MARTIN ,

MD

been appointed medical

director of the inpatient child and
adolescent psychiatric program at
BryLin Hospitals. The 20-bed ,
short-term program treats children and adolescents with attention deficit!hyperacti vity disorder,
dual diagnosis, conduct disorder,
depression, suicidaVhomicidal
behaviors and other emotional
problems. Martin, who is a board
certified child and ado lescent
psychiatrist, is in private practice
with Suburban Psychiatric Associates in Williamsville, NY, and
has been on BryLin Hospitals' staff
since May 1996.

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Elizabeth Olmsted Ross, MD '39, Honored
1999 Recipient of Lifetime Medical Alumna Achievement Award
Olmsted Ross has served in ovolunteer capacity with
many community organizations, as well as in on official
capacity with professional societies. From 1955to 1957, she
was president of the Buffalo Ophthalmologic Society; from
1962to 1964, she served as president ofthe New York Stole
Women's Medical Society; and from 1964to 1965, she was
president of the Women Physician League of Buffalo.
During World War II, Olmsted Ross served as a
medical officer in the Civil Air Patrol of Buffalo, Tonawanda
and Lockport. An avid pilot, she also instructed navigation
in the Buffalo Patrol and was a charter member of the
"99's", the Notional Women's Flying Organization. For
many years, she and her husband Ira G. Ross enjoyed
soiling their 38-foot Zeeland Yowl "Tonuki"
some 35,000 nautical miles on the Great
Lakes and the North Channel and chartering and scuba diving in the Caribbean.
In 1991, after her husband's
death, Olmsted Ross initiated on endowment for the Ira G. Ross choir in Medical
Informatics at the University at Buffalo
School of Medicine and Biomedical
Sciences. This choir was recently funded and will be
implemented during the upcoming academic year.
Recently she was honored by the Buffalo Blind Society,
which named their newly renovated area the Elizabeth
Pierce Olmsted Educational Center and by the Western
New York Blind Association, which changed its nome to
the Elizabeth Pierce Olmsted, MD, Center for the
Visually Impaired.
Throughout her active career, Olmsted Ross has also
published extensively in professional journals and mode
numerous presentations regarding her research in
ophthalmology.
For these and other contributions to UB and her
profession, it was with great pleasure that John R. Wright,
dean of the School of Medicine and Biomedical Sciences,
presented Dr. Olmsted Ross with the Lifetime Medical
Alumna Achievement Award on May 1, 1999.

iven that the theme for this year's Spring Clinical
Day was "Women's Health," it was only fitting that
Elizabeth Olmsted Ross, MD '39, was awarded o
Lifetime Medical Alumna Achievement Award
(see also page 28).
Following graduation from UB, Olmsted Ross
completed o rotating internship at the then-E. J. Meyer
Memorial Hospital. In 1941, she obtained on externship in
ophthalmology at Strong Memorial Hospital, followed by o
residency at the University of Illinois Eye and Ear Infirmary. Three years later she become the youngest person
on record to become odiplomate of the American Boord of
Ophtholmology. ln 1947, she also become a diplomate of
the American College of Surgery.
Olmsted Ross has been in private practice in Buffalo since 1944 and, over the
years has been affiliated with nine hospitals.
She received ocommendation for 50 years
of service at Millard Fillmore Hospital and o
citation for service at Deaconess Hospital,
where, in 1968, she was named chief of the
Deportment of Ophthalmology and choir of
the residency program.
In addition to starting her practice in 1944, Olmsted
Ross subcontracted with Curtiss Wright Corporation to
establish their Safety Goggle Program and industrial lighting standards. Later, working with Cornell Aeronautical
Laboratory, she initiated investigation of ocular hazards of
high-energy radar on technicians. This led to participation
in o research program for the Air Force Medical Center of
Griffiths Air Force Bose and Cope Canaveral, research at
Tufts University, and o contract with RCA to examine
personnel on their radar ship operating at Cope Canaveral.
In 1955, Olmsted Ross began teaching clinical ophthalmology at UB's school of medicine and in 1974 was
named clinical assistant professor, oposition she still holds.
Today, she is also o member of the UB's President's
Associates, the James Plott White Society's executive committee and the editorial board of Buffalo Physician.

hysician

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········· ·· ········ ·· ···································· · ······· · ············ ···· ······
.

I

GREGORY A. ANDREWS, MD
JD , has published a book,
titled The Complete Guide to Premedical Success (MedLaw Books
Inc. ISBN 0966052501). A re-

retired from
private practice in 1969
and a year
later moved

view written about the book states
that it is "an all-encompassing
guide containing crucial information for premedical students"
and concludes: "This 'nuts and

to Tequesta, FL.
In addition to
teaching, Stoesser

'93,

bolts' guide to achieving the
doctor dream covers many of
the common issues and questions that arise from students
considering medical school.
Dr. Andrews, dedicated to the
education of young people considering medicine, has created a
book that will be an asset on any
student's bookshelf. "

to Cleveland to
complete
his surgical
residency at
St. Luke's
Hospital. In
1950, he began
his
private
practice as a
surgeon and for
38 years was as-

S

practiced as a
board certified
surgeon from
1940-69 at E.).
Meyer Memorial Hospital

University starting July 1999, to
care for the growing population
of adults with complex congenital heart disease.

IN MEMORIAM
FREDERICK G. S TOESSER, MD
'29, a longtime Buffalo-area
surgeon, died March 8, 1999, in
Waterford Health Care Center,
Juno Beach, Fl. He was 95.
Stoesser served as an associate
clinical professor of surgery in
UB's School of Medicine and
Biomedical Sciences and taught
at the university for 32 years. He

®

during that time. A past president of the Buffalo Surgical Society, he also served as president
of the UB Medical Alumni Association, the Buffalo Academy of
Medicine and the Millard
Fillmore Hospital staff. Stoesser's
research included work on the
use of hyperbaric oxygen to treat
disease, and he was instrumental
in bringing the first hyperbaric
chamber to Buffalo. In 1956, he
received a patent for a vein stripper, the proceeds from which he
gave to the UB medical school for
an endowment to support medical students in financial need.
KENT L BROWN , MD '42, died
April 30, 1999, in St. Vincent's
Hospital, Erie, PA, after a brief
illness. He was 83. Following
graduation from UB, Brown, a
native of Westfield, Y, served
aboard the USS San Francisco
during WWII. In 1946, after discharge from the service, he moved

u

Amherst after a long battle with
cancer. He was 62. Schultz was a
clinicial assistant professor in the
Department ofMedicine and had

Note: Our e-mail address has changed.

and Millard
Fillmore Hospital, where he was chief of surgery from 1961 - 1967. He
also was a consulting surgeon
at DeGraff Memorial Hospital

B

ROBERT SCHULTZ, MD '65,died
March 27, 1999, in his home in

sociated with

and Lafayette General Hospital
JOSEPH KAY, MD '94, writes: "I
was married on ovember 2,
1996, to Kathryn Fox of Hamburg, NY. After finishing my Med/
Peds residency at the University
of Michigan Hospitals, I served
one year as pediatric chief resident at that institution. I will be
persuing further training in a
combined pediatric and adult
cardiology fellowship at Duke

Karen Brown Johnson of
Schenectady, NY; three sons,
KentJr. of Honesdale, PA, David
of Sherman and Garry of Columbus, OH; a sister, Martha Brown
Akin of Chautauqua, NY; and ll
grandchildren.

f

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served on UB's faculty since 1970.
He was also a past president of
the UB Medical Alumni Association. Schultz maintained a
private practice in internal
medicine, renal disease and

St. Luke's, where he eventually
became chief of staff. He also was
affiliated with St. Vincent Charity Hospital and Health Center in
Cleveland and was named chief

hypertension. In addition, he
served as chief of nephrology at

of staff there in 1980. Following
his retirement in 1983, Brown
left Cleveland and returned to

Millard Fillmore Hospital. He was
instrumental in the development
of Western New York's first outpatient dialysis center and
founded the High Blood Pressure Control Program of Western New York. A past president
and board member of the Western New York chapter of the
American Heart Association
(AHA) , he served on the board of

Chautauqua County, where he
served as a medical consultant
and a member of the board of
directors at Westfield Memorial
Hospital. Brown was keenly interested in the history of medicine, in medical personalities, in
forensic problems related to
medicine and in innovations in
surgical techniques. Many of his

directors of the New York State
affiliate of the AHA. In 1984, he
was named Man of the Year for
the AHA's Western New York

observations and information he
accumulated went into several
books and numerous scientific
papers he wrote. In 1946 Brown's

chapter for his dedication and
support in the fight against heart
disease. Schultz was also a member of the National Kidney Foundation, serving on the Western
New York board of directors and
executive commitee. In 1975, he
received the organization's Distinguished Service Award. Survivors include his wife, Sharon,
three sons and two daughters.

father-in-law and mother-in-law,
Garry Cleveland Myers and
Caroline Clark Myers, founded

Highlights for Children magazine,
still a leading periodical for children in America. Brown and his
wife, Elizabeth Myers Brown,
contributed greatly to the ultimate success of the magazine.
Survivors include a daughter,

p

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9

9

9

�Pubnona•y
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Patients admitted to the Pulmonary
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Fwe Star Care For Your Loved One
Rated outstanding in our community with five stars out of five,
according to The Inside Guide to America's Nursing Homes.

THE
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All major insurances and Medicare payments accepted.

�BUFFALO PHYSICIAN

Non-Profit Org.

STATE UNIVERSITY OF NEW YORK AT B UFFALO

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�</text>
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                    <text>State University of New York at Buffalo School of Medicine and Biomedical Sciences, Autumn 1999

�neaP Alumni and FPiends,
On the first day of orientation week,
incoming students, parents, spouses, family and friends participated in the second
BUFFALO PHYSICIAN

\10lumc 34

umber 2

annual White Coat Ceremony, held this year in the Center for the Arts. (See article on
page l2 of this issue of Buffalo Physician.) This event-based on an idea generated and

ASSOCIATE VICE
PRESIDENT FOR
UNIVERSITY SERVICES

brought to fruition by Assistant Dean Tom Flanagan-will no doubt represent one of

~mnh

the more memorable experiences for our students and, quite frankly , for everyone

Dr Ctrolc

Petro

DIRECTOR OF
PUBLICATIONS

Kathryn A Sawner
EDITOR
~tephame

A Unger

ART DIRECTOR/DESIGNER

\Lm J Kegler
PRODUCTION

C.mdy lodd
STATE UNIVERSITY OF NEW
YORK AT BUFFALO
SCHOOL OF MEDICINE AND
BIOMEDICAL SCIENCES

Dr john\\ nght Dean
EDITORIAL BOARD

Dr Benram P&lt;&gt;rtm. Charr
Dr Martin Brecher
Dr Hawld Brody
Dr lmda J Corder
Dr Alan J Dnnnan
Dr James Kanskt
Dr I Iizabeth Olmsted
Dr Stephen Spauldmg
Dr Bradley f Truax
'vis. Jenmfer \\tier
Dr f rankhn Zeplu" nz
TEACHING HOSPITALS

f-ne County MediCal Center
Kaleida Health-Ihc Buffalo General Hospttal
fhe Chtldren's llospnalufBuffalo
Mtllard ftllmore Gates Hospttal
\1tllard hllmore ~uburhan
llospnal
Ros\\ell Park Cancer lnsUtute
\eteransAffatrsWestern. ·e" )ork
I kalthcarc S} stem
Catholic Health S"tem\1ercy Health System
SISters of Chanty Hospttal
·,agara I ails Memorial Medical
Center
©The State universny of ew York
at Buffalo
Buffalo Ph1 sinan is published
quarter!} hy the State UniverSI!) of
:--:ew York at Buffalo School of
\kdicme and Biomedtcal Sciences
and the Oil ice of Publications. It ts
sent, free of charge. to alumm,
facultv students, reSidents. and
friend~. rbe staff reserves the nght
to edit all copy and submtssions
accepted for publication.

else involved.
This being the second incoming class to have participated in the White Coat
Ceremony, it dawned on some of our third-year students that they might
have "missed something. " Therefore, at their request, a similar White
Coat Ceremony was held a week later, on their first day of classes. Again,
this event, like the first, was made possible by the generous support of the
Medical Alumni Association, the Parents' Council, the james Platt White
Society and our other generous student supporters.
Incoming students were also treated to another form of welcome: a
completely renovated Butler Auditorium and G26 classroom. During my student
lunches last year, one of the most recurrent complaints about the medical student
experience here was related to the "dismal" classrooms and the condition of the student
lounge. Although Butler has been our best classroom, it lacked the most current
educational technology suitable for computer presentations, and the carpet had seen
better days. Those renovations, plus a new screen, are now in place. G26 was a slightly
different story and over the summer was completely gutted and refurbished. Finally,
with help from the Parents' Council and Polity, the student lounge has also been
refurbished and now represents a more hospitable refuge for the students.
Our plans for the coming year include completely refurbishing Farber 144
and establishing a new, more spacious and suitable student study-space and lockerroom facilities. Other projects are on the drawing board and will be implemented once
the necessary planning and funding processes have been completed. It is our conviction
that a good learning environment includes physical accouterments as well as all of the
more intangible essentials.
Our students also experienced another "first" this year as the United States Medical
Licensing Examination (formerly the

ational Boards) was offered via computer only.

(See article on page 8 of this issue of Buffalo Physician .) Although one of the advantages
appeared to be almost instantaneous feedback, the "spread out" nature of administration actually delayed the reporting of results. These standardized tests must be
subjected to statistical analysis and therefore require completion by all candidates
before validation is possible. So much for progress!
A final note: Dr. Tom Flanagan really has retired, having completed the initial two
years of his planned "retirement" as an assistant dean in the Office of Medical
Education. We are all indebted to Tom for making this invaluable contribution to the
school and look forward to his continuing participation in school events, even if on a
less formal or frequent basis. In the meantime, we wish him and Grace all the best as
they enjoy a well-deserved bona fide retirement.

John R. Wright, MD
Dean, School of Medicine and Biomedical Sciences

�VOLUME

34 ,

NUMBER

2

.-----------------~

AUTUMN

8

On the Trail of
Schistosomiasis

Electronic Testing
Makes Its Mark

2

14

1999

ARevolutionary
Look at Medicine

SCIENTISTS HUNT FOR

MEDICAL LICENSING EXAM

.JOSEPH GAGLIARD I

GENES IMPLICATED IN

NOW TAKEN BY COMPUTER,

ASSUMES PERSONA OF

THE DEADLY DISEASE

REPLACING PAPER- AND-

REVOLUTIONARY WAR

by S. A. Unger

PENCIL COUNTERPART

Doc TO TEACH HISTORY

photography by Frank Miller

by Corrine Streich

Hospital News

and Philip LoVerde

Photography by John Consoli

CHANGES COME TO

REGION'S VETERANS

ADMINISTRATION

SYSTEM

Research
•

POTATOES DELIVER

Medical School

HEPATITIS 8

•

•

VACCINE

Classnotes
HARRY L .

MOUSE CALLS

METCALF ,

GALLSTONESMD ' 60, RECEIVES

•

LIFESTYLE LINK

"THE SURFACTANT

BERKSON AWARD
STORY"- -AN UPDATE

•

GUM DISEASE AND

•

WHITE COAT CEREMONY

STROKE RELATIONSHIP

•

FACULTY MEMBERS

HONORED

Alumni
•

THOMAS FLANAGAN ,

PHD ' 6 5 , RETIRES AFTER

Student Perspective

LONG AND DISTINGUISHED

HEALTH - CARE POLICY:

CAREER AT UNIVERSITY

TO TREAT OR NOT

TO TREAT-POLITICS
Is AN ANSWER

by Joseph S. Ross

CC'VER

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C~RTER

THE (LASs oF 2003--White Coat Ceremony on
September 9, 1999, Initiates First-Year Students

�The

FORGE

S

IMPLICATED in
Schistosonriasis
I T's

OT DIFFICULT to understand why a sense of urgency underlies
The S. monsoni

efforts to find a cure for schistosomiasis. Victims of the disease are infected

species of schistoso·
miasis looms large in

with parasitic flatworms that flourish in their blood vessels, discharging

Dr. Philip LoVerde's

eggs that cause debilitating, often deadly, damage to their tissue and vital

life. As coordinator
for the World Health

organs. Currently, some 200 million people-the majority of whom are

Organization's

children-have schistosomiasis, making it the world's second most serious

Schistosomiasis
Genome Project, the
University at Buffalo
professor and

parasitic infection, next to malaria. According to the World Health Organization (WHO), about 10 percent of these cases are severe, resulting in an

associate chair of

estimated one million deaths each year. Compounding the problem is the

microbiology,

fact that only one drug is effective in treating schistosomiasis, and the

pidured right, is

parasite is rapidly developing resistance to it (see article on page 4).

determined to
out smart the deadly
flatworm.

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PHILIP

LoVERDE

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�GE

ETIC EPIDE~liOLOG\ STL D\ T\KES l~B SCIE TISTS TO

BY

S.

A.

UNGER

BH \ZIL

�PHILIP LoVERDE, PHD, professor and associate
chair of microbiology at University at Buffalo's School of
Medicine and Biomedical Sciences, is a scientist who
knows firsthand about the urgent concerns that drive the
search to find a cure for schistosomiasis. Widely regarded
as a leading international expert on the disease, LoVerde
has spent the majority of his career attempting to gain a
better understanding of schistosomiasis and ways to treat
its victims. Currently, he is coordinator for WHO's Schistosomiasis Genome Project and is a member of the
organization's Expert Panel on Parasitic Diseases. In 1998,
he completed a term as chair of the ationalinstitutes of
Health's Tropical Medicine and Parasitology Study
Section and today is president-elect of the American
Society of Parisitology.
In an effort to move schistosomiasis research in a
direction that utilizes the new tools and technologies
growing out of the Human Genome Project and other

related endeavors, LoVerde has embarked on an ambitious genetic epidemiology study aimed at identifying and
localizing specific genes influencing schistosomiasis infection and its clinical course. "Our goal is to improve our
understanding of the underlying genetic determinants of
resistance to reinfection and disease progression," LoVerde
explains. This understanding, in the long term, may
contribute to the development of vaccines or other interventions, he adds. In order to complete the study, which
is funded by a five-year, $1.25 million grant from the
ational Institute for Allergy and Infectious Diseases,
LoVerde and his collaborators have traveled to Minas
Gerais, a state in Brazil where schistosomiasis is endemic.

\11DI&lt;I L \I r111 \lou:ctL\H LL\LL
According to LoVerde, there are three components that
play a role in the transmission of infectious disease: (l ) the
environment where the agent is being transmitted, (2) the

�c. c.

Om goal is to improve our understanding

of the nnderlying genetic detenninants of resista11ce to
reinfection and disease progression.·")
infectious agent's genes that control its virulence and how it infects an individual, and (3)
the host and the host immune system and
genes that regulate the immune response to
the infectious agent. For years, scientists have
studied the environment and the genes of
infectious agents (in this case, parasites);
however, until recently, they haven't had the
sophisticated molecular and mathematical
(epidemiological) tools necessary to study
the contribution of host genetics to hostparasite interactions.
LoVerde and his group are interested in
exploring this latter component with the aid
of these tools. Specifically, they are interested
in what happens to an individual when exposed to the 5. mansoni species of schistosomiasis and , following that exposure, how the
immune system responds in terms of eliminating the parasite, something scientists call
protective immunity. By studying endemic
populations, they are trying to identify phenotypes , combinations of genes in individuals that imbue them with a specific trait. In
this case, the scientists are looking for immunologic phenotypes that confer on individuals the ability to: (1) become resistant
to schistosomiasis , (2) prevent reinfection, and (3) avoid development of
severe hepatosplenetic disease
(enlargement of the liver and spleen,
which can cause death).
Once this phenotype is developed,
the scientists will use genetic epidemiology tools (e.g., quantitative genetic
analysis , including variance components methods) to discover and test the
relative contributions of genes and
environment to the variation of a given
trait. After the role of host genetics is
clarified, they will use a gene-hunting
technique called linkage analysis to
home in on where the genes implicated
ducted.
in the phenotype are located on a I

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�c.c. We've

been able to show for

the first tin1e that inclivicluab \\'ithin the san1e fa1nil~ all respond in
a sitnilar fashion to an antigen-they sho\\T the san1e pheno~1)es.
in1n1unologically. to the infection.
specific chromosome. If specific genes are identified, scientists can then study their complex interactions with the
immune system and develop a much clearer understanding of how to devise interventions at the molecular level.

completed, involves treating everyone in the village and
taking blood samples in order to extract serum, which
contains antibodies. (Antibodies are protein molecules
produced by the immune system in response to
substances called antigens. An antigen is any foreign
FII Ll) lh . . , I \ H( II pH()\ II) I . . , K L' D \ 1'\
substance that, when introduced into the body, is recogTo accomplish this complex task, the UB scientists are nized by the immune system and targeted for destrucstudying the population of a village called
tion.) The third procedure involves
Melquiades, where they have conducted
studying the response of antibodies to
demographic and genealogic analyses to
schistosomiasis antigens , which enables
determine who lives there and who is
scientists to begin piecing together the
related to whom. With the assistance of
exact way a person's immune system
Brazilian physicians, they have also
mounts an attack and then , from that,
performed stool exams and completed
construct a phenotype.
ultrasounds to ascertain who is infected,
The immunologic phenotype the UB
the level of intensity for infection and the
team is interested in identifying pertains
clinical stage of disease. "We determine
to how T cells respond to antigens by
intensity of infection by counting the numreleasing molecules called cytokines. "In
ber of worm eggs per gram of feces, "
particular, we are interested in a sub-type
explains LoVerde. "An infection of 100
ofT cells called Th 1 because they produce
interferon gamma, a potent cytokine that
eggs per gram and over is pretty severe,
marking the point between clinical and
promotes the response of macrophages,
subclinical. " The results of these tests have
which can kill schistosomiasis parasites,"
revealed that 68 percent of the
says LoVerde. Other cytokines
village population is infected
they are interested in tracking
and that the mean egg-perare T F alpha, the overgram feces ratio is over 200.
expression of which correlates
Once prevalence and
with severe hepatosplenetic
intensity were determined , the
disease, and Th 2-type
research team set out
cytokines, which produce an
to identify phenotypes , a
antibody called IgE that has
process that involves three
been shown to be important
procedures. First, they used
in protective immunity against
their genealogic data to build
schistosomiasis. "So these rea family tree called a pedisponses are phenotypes, and
gree. " The pedigree in
we can measure them, "
Melquiades is made up of over 2,000
explains LoVerde. "And if there is in fact a
Schistosomiasis is
people, of whom 800 are still alive. And it
genetic
basis for these immunologic phenoendemic in the
turns out that the area we're studying is
types,
we
would expect to find familial
Brazilian state of
one huge pedigree.
ow, that's really
aggregation of them. As it turns out, this is
Minas Gerais.
significant because we can perform matches
the case. We've been able to show for the first
statistically and can look for the identifitime that individuals within the same family
cation of genes or associations of traits that result in all respond in a similar fashion to an antigen-they show
certain phenotypes we're measuring," explains LoVerde. the same phenotypes, immunologically, to the infection. "
The next procedure , which is currently being This is extremely important, LoVerde points out,

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�Parasitic flatworms of the Schistoso-

person's skin, they can penetrate

matidae family are responsible for

unbroken tissue and eventually

the three main species of schistoso-

enter the bloodstream, where they

miosis found worldwide (primarily in

feed and grow. The worms then

Asia, South America, Africa, the

migrate to the circulation of the

Middle East and the West Indies).

intestine or bladder, where they de-

Depending on the species of worm,

posit eggs that are discharged in the

the female flushes out 300 to 3,500

feces or urine. Thus, the cycle begins

eggs daily. Eggs that come in contact

anew-but often not before the

with freshwater hatch, releasing ciliated larvae that go in search of a snail
host to infect and grow within. Over time, microscopic worm larvae leave

Pictured above is study collaborator Fred Lewis, PhD, of the Biomedical

the snail and swim about in fresh-water. If they come in contact with a

Research Institute in Rockville, Maryland.

"because we know that in people with severe
hepatosplenetic disease, the number of parasites is an
important indicator of how well they do; yet we also know
that in people with the same high number of parasites,
some go on to develop severe disease, while others don't.
So, it's something besides just the number of parasites,
and we think it's host genes."

for genes believed to be implicated in the immunologic phenotype.
"In humans, there's a major locus on chromosome 5
called q3l-33 , which correlates with resistance to reinfection of schistosomiasis and, lo and behold, what we find
is that there are genes that produce cytokines that behave
a lot like lL-4, which controls lgE production. This means
that the level of expression of lL-4 by T cells is determining in part whether or not somebody is going to be
resistant or susceptible to reinfection, and so this major
locus seems to be controlling the host-genetic response,"
explains LoVerde.
"Once we identify the genes, this will give us insight, at
the molecular level, into the immunological mechanisms
that account for either disease resistance or disease
progression. And then what we can do is intervene,
because we will know what the target is and we will know
what we have to focus our vaccines on, as well as ways to
manipulate those vaccines." +

TIIIIIL IIOHCI L'-,
With an immunologic phenotype established, the
researchers are using genetic epidemiologic methods
described earlier to quantify the relative importance of
genes , environment and gene-environment interaction
for determining a given phenotype. According to
LoVerde, current results point to genetics accounting
for as much as 45 percent of the host's response .
In the final stage of their study, they are using the
powerful statistical technique of variance components
analysis combined with linkage analysis to search
B

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�BY NICOLE PERADOTTO

Medic Ilice

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Cl

hat's because last spring, the Class of
200 1-collectively they represent some
17,000 students nationwide-became
the first to take the computerized
version of the Step One exam. By this
fall, all three steps will be offered only
on computer, following the decision by
the ational Board of Medical Examiners ( BME) to replace the USMLE
paper test with its high-tech "e-test"
counterpart. That's right: The sharpened No. 2 pencil has at last given way
to the mouse. And such a change can trigger exam
anxiety even among children of the computer age .
"There was definitely a lot of concern about the
test-more so than in years past, I'm surebecause the game was changing completely, and we
were the first to play by the new rules ," Adams says.
In fact, the NBME first began considering a change
to computer-assisted testing 22 years ago, although
they didn't start working toward that goal until
1996. The new format follows a national trend at
century's end that has seen standardized test takers
at various educational levels go from shading in
ovals in neat rows to pointing and clicking their way

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through exams. In addition to the USMLE, such
standardized tests as the Graduate Record Examination (taken annually by 400,000 people) and the
Graduate Management Admission Test (taken
annually by 200,000 people) are now computerized.
In most countries, the Test of English as a Foreign
Language is also offered electronically.
"The biggest reason we went this way was security," explains BME president Tom Bowles, MD.
"It's very hard to steal exams that have been administered electronically. "
Another improvement over the conventional
format is convenience, as the step exams can

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�ILLUSTRATION

BY

now be taken throughout the year rather than
just biannually on set dates.

'

omputerizing the exam will allow much greater
scheduling flexibility and convenience than in years
past," says Frank Schimpfhauser, PhD, assistant
dean for educational evaluation and research at UB's
School of Medicine and Biomedical Sciences.
"Students can arrange to take the test based on their
own study needs and academic schedule. Also, those
who have had to change their test date-either for
illness or for another reason-are finding the new
format much more accommodating to their needs."
Since it emerged on the scene more than a

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decade ago, computerized testing has not received
universal passing marks however. One concern
has been that with so many test dates available,
opportunities for cheating will abound. Other critics worry that the tests are unfair to students who
are not computer literate and question whether
e-testing is worth the hike in exam fees that typically come as part of the new package.
"The computer doesn't magically transform a
test into a better test," notes Robert Schaeffer,
director of the ational Center for Fair and Open
Testing, in Cambridge, Massachusetts. "But it seems
inevitable that once you have the technology, people
want to use it. So you have these multiple-choice

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�(·Testing
"There was definitely a lot of concern about the test-more so than in
years past, I'm sure-because the game was changing completely, and we
Were the first tO play by the neW rules." - Christopher Adams, Class of 2001
marathons whose existing flaws may
only be reinforced on computer."
Furthermore, he points out, computer tests end up costing students
more on two fronts. First, the price tag
for the test increases, which will be the
case for medical students starting in
2000. Second, whenever the format of
a test is altered, students tend to invest
in updated preparatory classes, such as
Princeton Review and Kaplan Preparatory Classes.
nd then there's the dreaded "black
screen of death," when computers
craSh beroreor during an exam.
That happened to
a group of students
taking Step One exams thispastsummer,
acknowledges Bowles
of the BME. However, he adds, the affected students in this
case were accommodated with "fairly rapid
re-testing. "
"With the paper-and-pencil exam,
we had disruptions caused by hurricanes, exploding boilers, bomb threats
and so forth," he continues. "If you take
the total number of examinees who
experienced disruptions this time
around, it's not a whole lot different
from the previous era."
'Tm sure the students who are
affected by the glitches think it's not
good, but when you look at the total
picture, it's been very smooth," says
- Alice Wooden Kelly, director of
administration at the BME. She feels
students will appreciate the many
benefits of e-testing, including receiving their results faster, more than they
will mind some of the drawbacks to
the new format, such as paying a little
more for the test.

®

B

Beyond having been transferred to
the computer, other aspects of the step
exams have changed dramatically. The
Step-One exam, for example, has been
reduced from a 700-question, two-day
test, to a 350-question, one-day test.
The Step Three exam, which will be
offered for the first time this fall,
incorporates sophisticated case simulations into the 14-hour exam. Test
takers will be presented with "virtual"
patients, and will be expected to take
a history, order lab tests and so forth.
As the test progresses, the patient's
condition will change based on the
student's decisions. "The case
~.J&lt;.
simulation is virtually
impossible on a paper, , and-pencilexam,"Bowles

f•

·~ says. "We think it challenges the examinee
to a higher level of
clinical reasoning. "
As he watched the
Class of 2001 ready
itself for e-testing,
Schimpfhauser, too,
noticed severe test dread hitting the
student body. "Everyone was extremely
nervous because it was a new
situation," he says. "For many, the
computer testing is perceived as an
improvement in the examination
procedure, but some students thought
that it would compromise their ability
to show what they know."
Danielle LaPrairie counts herself in
the latter group. She excels at standardized tests-the kind that involve
filling in hundreds of digitype bubbles
with a o. 2 pencil. She worried that
staring at a computer screen for seven
hours would strain her eyes. She wondered how she would adjust to taking
notes with a marker on a dry-erase
board rather than working through
problems on scratch paper. In short,
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she feared that any change in the formula she knew so well might adversely
affect her score.
Then she practiced for the exam on
the CD-ROM she received with her
registration materials. "After that,
I felt much better about taking the
test on the computer. It brought it
back down to being worried about
what type of questions would be
asked," she says.
And how did she like the exam? "I
had never sat in front of a computer for
that long. I was very nervous about that.
It was forcing me to change the way I
take tests. But looking back on it now,
I don't think it had that much of an effect
on how I did."
Overall, UB students had few complaints about the new Step One exam
and tended to prefer it to the paper-andpencil test. While some worried that an
abridged exam would mean broader
questions (which it didn't), their pretest anxiety was somewhat assuaged by
the fact that the exam had been cut back
to one day.
While taking the USMLE at Sylvan
Learning Centers, where the exam is
administered locally, Michael Duff
didn't miss his o. 2 pencil for a minute.
"It was just so simple," he saysreferring to the format; that is, not the
questions. And Duff doesn't consider
himself among the most computer
literate of his generation. He was a
physics major as an undergraduate, so
his calculator was his best friend.
But as an instructor of an MCAT
prep course, Duff recognizes that one
of the biggest mistakes students make
in a paper-and-pencil test is answering
questions in the wrong order. "I liked
this test because I didn't have to go
back and forth between a test booklet
and an answer sheet. The questions

I

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�The Smfactant StoiY-An Update
INFASURF G_OES TO MARKET

WESTERN NEW YORK HEALTH RESOURCES

WESTERN NEW YORK HEALTH DATABASE

FULL TEXT REPORTS SECTION

FACILITIES , ORGANIZATIONS , AND AGENCIES

OTHER SOURCES OF INFORMATION

HE SPRI G 1999 ISSGE of Buffalo Physician featured
a Special Report titled "The Surfactant Story," which
chronicled pioneering contributions made to the
field of surfactant therapy by University at Buffalo
scientists and physicians over the past four decades.
Prominent among those profiled in the article
was Edmund "Ted" Egan, MD , UB professor of pediatrics
and physiology and president and chief operating officer of
0 Y, Inc. , a company he founded in 1985 to manufacture
and distribute Infasurf, an exogenous surfactant product
that he and his colleagues had
developed for the treatment of
neonates with respiratory distress
syndrome (RDS) .
At the time that issue of
Buffalo Physician went to press
in May, 0 Y, Inc., was unable
to commercialize Infasurf due to a legal challenge from
one of its competitors, Abbott Laboratories, which in
1994 claimed Infasurf infringed on the patents of its
surfactant drug, Survanta. In September 1998, a jury in
District Court in Buffalo ruled in favor of Abbott
Laboratories, but a final judgment had not been entered.
Onjune 23 , 1999,Judge Richard]. Arcara ruled that
Abbott Laboratories failed to prove 0 Y, Inc. , had infringed on its paten I.. The judge also issued an "estoppel,"
which prevents Abbott Laboratories from claiming
infringement based on a principle-of-fairness doctrine.
"We're jubilant here, " says Egan . "This is the
culmination of a 14-year odyssey. That's how long we've
been working on this project."
The decision will allow 0 Y, Inc., to proceed with
manufacturing Infasurf at its facility in the Baird Research
Park on Sweet Home Road in Amherst, New York. "We
will also be able to hire more employees and to rehire
employees who were laid off after the decision that came
out last year,"says Egan.
In addition to being used a:u~ treatment for neonates
with RDS , Infasurf is also currently being studied in
clinical trials involving pediatric patients who receive the
drug for a wide spectrum of respiratory disorders. In a
study published in january 1999 in Critical Care Medicine
(Vol. 27, o. 1), it was shown that these patients
experienced rapid improvement in oxygenation and , on
average, were extubated 32 percent sooner and spent 30
percent less time in the pediatric intensive care unit than
control patients. As a result, larger, blinded, controlled
studies are planned. +

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~

I

Lifelong Cultivation
of Character
WHITE COAT CEREMONY
I NITIATES C L ASS OF 2003

'\1 ALGl-ST

9, 1999, the Univer-

sity at Buffalo's School of Medicine
and Biomedical Sciences welcomed
its Class of 2003 at the second
annual White Coat Ceremony, held
in the Center for the Arts on the
orth Campus.
The ceremony is
now a rite of passage
for first-year medical
students , who are
reminded of their responsibility to "care" as
well as "cure" patients
by endorsing a psychological contract of
professionalism and
empathy at the start of their medical
careers. To formalize this commitment,
they are officially "cloaked" with their
first white coats; then, as a group, they
recite the Physician's Oath, a modern

Sean Garvin, left, and Micheline Lubin, above, proudly "cloaked" with their new white coots.

version of the ancient
Hippocratic Oath.
Opening remarks were
made by medical school
deanjohn R. Wright, MD,
who highlighted the fact that the Class of
2003 is the last class entering the school
this millennium. The Physician's Oath,
he added, was "specially designed for our
school because the ethical basis of medicine is an evolutionary process" and
one that requires
updating to reflect
current issues."
Number of applicants: 2,200 (440 of whom were interviewed)
The students were
Class size: 13B (plus 4 MD/PhD students)
then addressed by
Where they call home: 69 of the students ore from Western New York,
Wesley L Hicks,
21 from the "extended" Western New York region, 13 from upstate New
DDS, MD '84, an asYork, 33 from downstate New York, and 2 from out-of-stole.
sociate professor of
Female-Male ratio: 76 women and 62 men
otolaryngology at
Undergraduate degree institutions: 2B of the students graduated
UB, who implored
from the University at Buffalo, 19 from Cornell University, 9 from Conisius
them never to forCollege, and Bfrom the University of Rochester; other institutions
get that "you are not
represented include SUNY at Binghamton, Yale University, Johns Hopkins
here only because of
University and Rochester Institute of Technology
your grade point
Average science grade point average: 3.6 (overage overall GPA, 3.6)
average and MCAT
Average MCAT score: 9.B
scores ... but you

A"Class" Profile -2003

are here today because your letters of
recommendation and your interviews
revealed you as having character.
"In my view, character is a sense of
integrity, noble purpose, thoughtful
determination, intellectual curiosity and
generosity of spirit," he added. "As I
think of my colleagues, teachers and
mentors whom I admire and respect, I
know this to be true."
Hicks also reminded the students that
"learning histology is a semester's
challenge; it's finite. Integrating honesty,
determination and wisdom into your
practice of medicine is a lifetime's commitment. If you remember nothing else
from our conversation today, remember
this: What translates the mechanics of
medicine into the art of healing is the
character we bring and communicate at
our patients' bedsides."
In concluding Hicks noted, "But to
live your lives and apply to your practice
of medicine the highest standards of character requires individual effort, introspection and, at times, emotional angst.
Above all, it requires your giving yourselves to something outside of self." +
- 5 . A . UNGER

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�Two Faculty Members Honored

MARK YOUR CALENDARS

r \CGLT't \1[\,1BERS 1 THE SCHOOL OF MEDICI E and Biomedical
Sciences were honored this summer at the school's annual faculty meeting.
BRUCE A. HoLM, PHD, professor of pharmacology and toxicology and of
gynecology-obstetrics, and associate dean for research and graduate studies,
received the George Thorn "Young Investigator" Award. This award recognizes investigators under age 45 who have demonstrated outstanding scientific achievement and the potential for continued contributions to the academic
programs and creative environment of the School of Medicine and Biomedical
Sciences. Holm, whose work has attracted millions of dollars in grant awards to UB ,
won the award for his research on lung surfactant and oxygen
toxicity affecting alveolar cells. He was also recognized for his
exemplary commitment to UB students and academic programs.
George Thorn, MD '29, is one ofUB's most distinguished alumni.
In 1939, in recognition of his research on Addison's disease , he
received the highest honor that can be bestowed upon a medical
scientist in the United States-the Gold Medal , awarded by the
Bruce A. Holm, PhD American Medical Association. In 194 2, he accepted the Hersey
Professor of Theory and Practice of Physics at the Harvard Medical
School, which began his long association with that institution. Later in his career,
Thorn was named president of the Howard Hughes Medical Institute, and in 1984
he was appointed chair of its board of trustees.
·MAURIZIO TREVISAN, MD, professor and chair of the Department of
Social and Preventive Medicine, received the 1999 Stockton Kimball
Award, honoring a faculty member for academic accomplishment
and worldwide recognition as an investigator and researcher.
Trevisan is known internationally for his research into cardiovascular disease risk factors. He is primarily responsible for establishing
the Women's Health Initiative at UB through a $10 million grant M . . T . MD
aunz1o reviSan,
from the ational Institutes of Health.
Stockton Kimball, MD '29 , was dean of UB's School of Medicine from 1946 to
1958. Dr. Kimball's contributions to the training of physicians in Buffalo spanned
more than a quarter of a century. Under his dedicated leadership as dean , the
medical school attained new heights of recognition. +
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Our Health Care Industry at the
Crossroads, What Lies in the Future?

Location:
Date:
Time:
Keynote
Speakers:

Adams Mark Hotel
Wednesday, November 17, 1999
8 a.m.-5 p.m.
Nancy Snyderman, MD
Medical Correspondent on
ABC's Good Morning America

George Will
Columnist, Washington Post

Present

Michael Millenson
Author of Demanding
Medical Excellence

Panel
Discussi
Physicia
Panelists

Community and business leaders
Health-care provider, CEOs, Insurers
l. N. "Nick" Hopkins, MD

Irene S. Snow, MD
Allyn Michael Norman, DO
Registration Fee: $80 For more information, call
Independent Health Foundation at 635-4959.

@ Minority Alumni Reunion
University at Buffalo School of Medicine
and Biomedical Sciences
"Coming Together in the New Millennium"
Date:
April 7-9, 2000
Place:

University Inn, Buffalo, New York

For more information, contact Dr Carolyn
Hamilton, assistant dean for Mmonty Affairs.
Phone: (716) 829-2802; fax: (716) 829-2798;
or e-mail, cah7@acsu.buffalo.edu

In the summer issue of Buffalo
Physician a graduation picture of
Maria LoTempio and John
Carter was published in the
table of contents. In the
photograph, Carter
was incorrect~
identified as Patrick
D'Abbracci.

Match Day /Northwestern University
Under the Match Day listings in the
same issue, McGaw Medical Center of
Northwestern University was incorrectly listed as McGaw Medical Center
Northwest or W under the names
james Flaherty, Henry Lee and Amy
Weinstein.

Peak Experience
The normal pulse oximetry rate is
approximately 96-100 percent,
depending on the altitude of the
patient. It is not 90-100 percent as
stated in the article "Peak Experience," published in the summer 1999
issue of Buffalo Physician.

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�JOSEPH GAGLIARDI'

MD '7 9'

TEACHES KIDS WHAT PHYSICIANS
USED TO DO FOR A

LIVI~G

SLOUCHED IN CLASSROOM SEATS, the seventh and
eighth graders wear the guarded, "what's-this-guy-tryingto-pull?" expression of adolescents when their teacher
introduces Dr. Alexander Dobbs. Authentically dressed as
a regimental physician and surgeon in General George
Washington's army, Dr. Dobbs (aka joseph Gagliardi, MD,
Class of 1979, family physician and addictionologist in
Columbia, Maryland) jumps directly into his monologue.
"Despite the victories at Trenton, Princeton and Saratoga,
the war for independence is floundering. The small, poorly
fed and ill-equipped Continental Army suffers from many
maladies," he says in the present tense, with just a shading
of colonial syntax and mannerisms.

��When he

[Dr. Dobbs} tells the students that he washes his

instruments in plain water between operations, some are appalled
and others refute it. Even junior high school students understand
the necessity of sterilization, but they have little understanding
that there was life before ER and Chicago Hope.
welcome lecturer at local
schools, historical societies and medical conferences, Gagliardi delights
teachers with the unique
learning experience
he brings to their classrooms. However,
media-sophisticated kids who have
grown up with Mortal Kombat and
MTV music videos are not an easy audience for a serious guy in a funny suit.
So Dr. Dobbs starts slowly, commenting on the boys' strange attire , at
the rips in their jeans. He asks the girls
why they are there (girls often did not
have an opportunity to go to school in

colonial times). Then he gets all of the
children out of their sedentary slouches,
and teaches the girls to curtsy and the
boys to bow.
ow they are amused. He talks about
himself. Like Benjamin Franklin ,
Dr. Dobbs is one of 17 children. He was
told at the age of 10 that his father could
no longer afford to keep him, and he was
apprenticed to a physician. "Before I
could begin my medical studies, I had to
learn to read ," Dobbs says. ow the kids
start asking questions , and he gives them
an anecdotal but accurate overview of
the rigors of daily life and the social
mores of colonial times.
After nine years of
honing his presentation skills, Gagliardi
knows just how gory
to make the medical
details of his lecture,
and when to ask
for volunteers. Using
reproductions of colonial surgical instruments , he simulates a
leg amputation in a
military hospital during a Revolutionary
War battle.
By introducing them
to medical practices of
the past, Gagliardi
hopes to broaden their
understanding of modern medicine and to
teach students that
what happens in a
doctor's office today
isn't so bad. "Maybe
they won ' t scream
bloody murder if the
doctor wants to take a

P

throat culture, now that they know that
in Dr. Dobbs's day he'd have bled their
necks to cure a sore throat. "
Gagliardi started speaking publicly
in 1990, when his son's social studies
teacher asked if there were parents with
special interests who would come to
class to talk about them. An avid student
of the history of medicine, Gagliardiplaying himself- gave an overview of
practices from the American Revolution
to the Civil War. The students were
impressed. Some even told their parents
that something of interest had actually
happened at school that day and they
related grisly details about how legs were
once chopped off without anesthesia or
the sterilization of instruments.
After he had given several more lectures as himself, Gagliardi decided that
a more dynamic approach would be to
allow students to interact with a physician from the colonial period. The transition, he figured, would "give me a
chance to get out of the 20th century
completely and play around in the 18th."
But he wasn't altogether confident.
Lecturing came easily to him , but could
he be convincing as Dr. Dobbs? To make
his characterization as authentic as
possible, Gagliardi read in depth about
late-18th century American life, concentrating not only on general history
but also on the subjects of dress, social
customs, medicine and science.
He also traveled repeatedly to
colonial Williamsburg to observe the
authentically dressed impersonators of
aristocracy and tradesmen at work.
Although he admired their skill and
the physical beauty of the reconstruction , he thought that visitors should be
given a truer picture of life in
colonial times.

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�o emphasize the contrast
between the life of a child
today and that of one
250 years ago, Gagliardi
decided to stress details of
Dobbs's own childhood.
For Dobbs, not having any schooling
was not nearly as bad as having no time
to play. To survive, average families
worked together from dawn until dark
every day except Sunday-which was
spent praying in church and doing other
"quiet" activities. One Sunday, the
young Alexander Dobbs was seen
running and playing, which led to
Dobbs's father being fined by the church
warden. Because the fine was much
more than his father could afford, the
boy was sent from home to work as a
physician's apprentice.
On the eve of every public appearance, Gagliardi goes to bed thinking

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about these details, as well as other
aspects of Dobbs's life. In the morning
he puts on his long coat, one-size-fits-all
breeches (with a knotted string as a belt),
a three-cornered hat, and riding gloves.
On the way to school he plays tapes of
colonial music on the car stereo.
"When I step out of my car, I go into
the school office and introduce myself
as Dr. Alexander Dobbs," explains
Gagliardi. 'Tve never had any acting
experience, so this helps keep me
in character."
The more convincing he is as
Dr. Dobbs, the more curious the students
become about women's roles, disease
causation, and other issues they can learn
about from their 18th-century visitor.
The combination of medicine and
social sciences in Gagliardi's outreach
to students is a logical progression of his
educational background and interests.

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As an undergraduate at the University
of otre Dame, he studied sociology
and education, intending to become a
social studies teacher. During his senior
year, a course on the sociology of medicine sparked his interest in the science.
He entered medical school at the State
University of New York at Buffalo in
1975 and completed his family practice
residency at the University of Maryland
in 1982. While in medical school,
Gagliardi started the Mad-Med newspaper and, in conjunction with classmate
Peter Condra, MD '79, founded the
Mad Med Choir. He also established the
Mad-Med Talent Show, the forerunner
of the school's current talent show.
Today, he practices with Patuxent
Medical Group in Columbia, Maryland,
where he lives with his wife, Diane, who
works in early childhood education, his
17-year-old son, ] oe, and 14-year-old

�"May be they won't scream bloody murder if the doctor wants
to take a throat culture, now that they know that in Dr. Dobbs's
day he'd have bled their necks to cure a sore throat. "
daughter, Christine. He also serves as an invited to the Universal Studios in Or- from Vermont to Alabama.
associate professor of psychiatry at the lando, Florida, where he appeared on a
Predictably, when he speaks before
University of Maryland, training third- live show called "Ask the Family youngsters, there are always a few who
year medical students in addiction Doctor," which airs on America's Health try to trick Gagliardi into admitting that
issues; and as a clinical instructor, work- Network. In addition, he has lectured to he drives a car and gives his patients
ing with students who rotate through his numerous medical organizations, aspirin. Once while demonstrating a leg
practice in four-week intervals.
amputation in a lOth-grade
Since first donning the garb
history class, he saw a boy slip
and persona of Dr. Dobbs,
out of his chair onto the floor. "I
Gagliardi estimates that he has
thought, 'There's a comedian
reached more than 10,000 stuhere,' and waited a few seconds
dents across Maryland. (All perfor him to get up. When he didn't,
formances are done in his free
I went over, saw he had fainted,
time and without charge to
and helped him come around."
schools and historical organizaGagliardi later learned that the
tions throughout the state.) In
boy passes out whenever he hears
recent years, he has also spoken
discussions about blood and
before the American Academy of
gore. That was the only time
Family Practitioners at its annual
Dr. Gagliardi has had to stand in
conference in Boston and was Mock amputation elicits strong reaction from a captured audience. for Dr. Dobbs. +

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I

�HIS FALL, THOMAS D.

fLA AGAN, PHD,

announced his retirement from the University at
Buffalo School of Medicine and Biomedical
Sciences after a long and distinguished career. As
Dean Wright explains in his message in this issue
of Buffalo Physician (see inside front cover),
Flanagan retired as professor emeritus of microbiology
in August 1997, but agreed to remain at the university
to serve for two years as assistant dean for student
and curricular affairs in the Office of Medical
Education (OME).
Flanagan, who received the Dean's Award for
Distinguished Service this year, came to UB in 1962
to begin work on his PhD. Following graduation, he completed a
postdoctoral fellowship in what was
then the Department of Bacteriology
and Immunology, where he studied
under Almen Barron and Ernest
Witebsky. In 1966, he was named an
instructor in the Department of
Microbiology.
In 1973-1974, Flanagan was a
guest research worker in the Department of Tumor Biology at the
Karolinska Institute in Stockholm,
Sweden, and visiting professor of
microbiology at the University of
Linkoping, also in Sweden. Two years
after returning to UB, he was named
professor in the Department of
Microbiology. In 1982, he again took a leave from UB
to serve as a guest research worker at the ational
Institutes of Health in Bethesda, Maryland.
In 1986, Flanagan was appointed acting chair of the
Department of Microbiology at UB, and in 1987 he was
named chair, a position he held until1990.
"Tom served as acting chair of the Department of
Microbiology during a tumultuous period in the
department's history and served as chair during an
equally challenging time," says Wright. "For over two
decades he directed the sophomore Medical Microbiology course and, for much of that period, I was his
counterpart in Pathology. Through this long relationship , I developed enormous respect for Tom,
particularly for his dedication to students."

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According to Wright, Flanagan's major research
interest was virology and for much of his career he
headed the Virology Laboratory both at Erie County
Medical Center and at UB. In addition to many other
school-wide activities, he promoted student research
and chaired the school's student research fellowship
committee for almost 20 years.
"When I was appointed Interim Dean and needed
someone to help out in the Office of Medical Education-in particular, to address the needs of first- and
second-year students-! looked to Tom Flanagan for
help," says Wright. "Then·, in September 1997, we took
advantage of the fact that he was willing to continue his
part-time work in OME, even though
he had just assumed emeritus status
in the Department of Microbiology."
Although the position was
officially part-time, according to
Wright, "Tom not only exceeded any
mythical time commitment limitation
previously established, but he brought
his wisdom, years of experience with
students and his enormous compassion to that office. We are greatly
indebted to him, not only for his years
of service as a faculty member and
leader within the Department of
Microbiology, but for the many important contributions he has made to
OME over the past two years."
In commenting on his years of
service at UB, Flanagan says, "One of the things that's
been very exciting about working here is that there's
been a lot of change, ferment and energy towards growth
and increase in stature for the university, and this is
something I see continuing." Teaching, he adds, has
been an especially rewarding endeavor: "It's been
frosting on the cake to be able to teach-to interact
everyday with young people who are well motivated in a
balanced way, who retain their idealism and who know
what they want to accomplish. It's very energizing for
everybody involved."
Retirement, says Flanagan, will involve "anything
that can fit around playing golf. " He adds that he and his
wife, Grace, plan to spend about five months each year at
their home in South Carolina. +

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�s

········· · ········ · ················· · ····· · ···························· · ················· ·

BY

SCOTT

THOMAS

Change Comes to the Veterans
Affairs Healthcare System
WESTERN NEW YORK FACILITIES RETOOL AND RESTRUCTURE

YO E CASTING A WARY EYE

line would have to be pleased with what's been going on within

Editor's note: he following

the Department of Veterans Affairs (VA) Western New York

ltuUt IStlltWS(InQ

hrce-pmt senes

Healthcare System.

highlighting t han~cs

111

the

A series of reorganizational moves and the establishment of

ealth-t are deliver}
~} ster11.s

in Western

several community-based clinics are enabling the VA to deliver

C\\

health services more conveniently, more effectively and less

Yorll. Pre\ to us articles
gtl\ C

(Ill

0\ ei\IIC\\

on the federal government's bottom

expensively than ever before. And because the system has been

oj

( hanges that resulted m the

retooled to emphasize primary and preventive care, the VA has

onnatwn of the Kalc1da

become a more well-rounded health-care delivery system, not just

lealth S\ stem (Bufblo

a place where veterans go for acute and emergency treatment.

Ph\ siCian, Summer 1998)
c nd in the reconj1guring

of

rhe Callwlu Health

.'&gt;}stem (Buffalo Physician,
Spring 1999).

11

®

historic 11-story Buffalo facility on Bailey
Avenue was integrated organizationally
with the VA's Batavia facility, creating
what is now a single management structure that allows more resources to be
directed toward patient care. Goals of
the integration have included the establishment of patient-privacy projects,
purchase of high-tech equipment and
upgrades in patient amenities.
In addition to patient-care concerns,
changes in the VA Western ew York
Healthcare System have been spurred
by the twin necessities of every healthcare delivery system today: competitive
pressures and cost containment. In the
4 7-counties included in the VA Healthcare etwork of Upstate ewYork, the

"Often, veterans were coming to us
only when they needed emergency
services," says Roger Maddigan, who, as
manager of medical VA care, is responsible for overseeing the agency's
community-based clinics and primarycare services. "Back in 1995-1996, we
saw that we needed to change and to start
providing general health services
that emphasize preventive care and the
treatmentofchronicdiseases-things that
we see a lot of in our population," he
explains. "Since then, there's been a shift
to primary care. We've been telling people,
'Don't wait until you're so sick that you
have to come to the emergency room."'
It was also during this time-in March
1995-that administration of the

Buffalo

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�············· · ········ · ·· · ···· · ········ · · ··· ·········· ·· ··· ···· ·········· · · ·· ····· · ······· [ i ]

population of veterans is expected to
shrink by 22 percent over the next 10
years, according to VA statistics, which
means fewer potential patients making
use of the system. Also, because many
veterans obtain their care outside the VA
system, the VA has recognized the need
to emphasize patient services and quality
of care in order to help it compete with
other providers.
Additionally, the system faces the
challenge of a patient population sig-

veterans than ever before. We find an
increasing number of veterans who either
opt to come here for their care, for which
we receive reimbursement from their insurance company, or who come because
they have no private health insurance.
"We believe we provide superior health
care because we concentrate on preventive
health care. For example, we look very
closely at smoking, hypertension and diabetes, and we have some very aggressive
programs to treat these conditions."

emphasized outpatient care, to the
point where 75 percent of surgeries are
done on an outpatient basis. During
last year alone, 412,121 outpatient
visits were made to VA facilities in the
Western ew York system.
This turn toward outpatient and clinical care is reflected in changes in the
delivery ofservices at the agency's Batavia
hospital, as well as in the establishment
of community-based VA clinics in
Jamestown, Dunkirk, iagara Falls
and, most recently, Lockport.
"We saw that there are veterans living in outlying areas,
and it was very much a disadvantage for them to travel long
distances for their primary
health care," Maddigan says.
"So we established clinics in
outlying areas to serve these
populations. We're also looking at establishing additional
clinics within the City of Buffalo , particularly in South
Buffalo and on the East Side.
There's a population of veterans who find it difficult to travel
to Bailey Avenue, even from a
relatively short distance."
Operation of the community-based clinics is contracted
out through a bidding process.
The Niagara Falls clinic, for
example, is operated by Horizon Health Services, a private,
not-for-profit company, which
currently serves 600 to 700
veteran clients at the site,

The Bailey Avenue facility is increasing outpatient services to the point where 75 percent of surgeries ore done onon outpatient basis.

nificantly older than the general public.
In 1998, 47 percent of all patients in the
VA's upstate network were over age 65.
"Some people feel that the VA is dying
and going out of business. That is
totally wrong," Maddigan says, adding
that 18 percent of eligible veterans in the
region currently seek care in VA facilities.
"Last year we treated more individual

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ne notable outcome of these recent
changes is that the number of beds at
the VA's Bailey Avenue facility has
been reduced to 167, down from
approximately 500 beds a decade ago
and a high of 900 when it opened in
1950. With two primary-care clinics
located at the Bailey Avenue facility,
however , the VA has increasingly

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according to Jennifer Vogel, MS,
Horizon's director of medical services. Before its association with
the VA, she says the clinic was
best-known for its mental health
services, particularly for patients with
substance abuse problems. With the
addition of the VA contract, Horizon
began providing primary care services,
which now account for a significant
portion of their business.

�[1] . . . . . . . . . . . . . . . . . ... . . . . . . . . . . . . . . . . . . . . . . ... . . .
:.: · ·

Laboratories and PFr Center Accessible to Non-Veteran Patients
lung function in patients with such disorders as chronic
obstructive lung disease, asthma and interstitial lung
disease, as well as damage from asbestos and other
irritants.
t The Cardiopulmonary Exercise Laboratory, offering
exercise studies that measure oxygen uptake, carbon
dioxide output, heart rate and cardiac electrical activity
during progressive exercise on a bicycle ergometer or
treadmill, and measurements useful in a patient experiencing unexplained shortness of breath, for example, or as a
training aid to serious athletes.
Physicians interested in referring a patient to any of
the three labs can call the VA at (716) 862-8635.
Physicians may also refer patients, regardless of their
veteran status, to the VA's Positron Emission Tomography
(PET) Center, which is a joint venture between the
Unversity at Buffalo and the VA. The center, which is
directed by Alan H. Lockwood, MD, UB professor of
neurology, nuclear medicine and communicative disorders
and sciences, can be reached at (716) 862-8871.

The Veterans AHairs Healthcare System is
assigned by law to treat veterans of America's armed
forces, but there are circumstances in which it accepts
non-veterans as temporary patients. For example, it was
recently announced that three specialized laboratories
at the VA's Bailey Avenue facility will begin accepting
non-veterans by referral, pending final approval.
VA physician Brydon Grant, MD, a professor of
medicine, physiology and biophysics at UB's School of
Medicine and Biomedical Sciences, and head of the
school's Division of Pulmonary and Critical Care
Medicine, says the labs became accessible to the public
because they're operating so efficiently that additional
capacity has become available.
THE LABORATORIES ARE :

t The Sleep Laboratory, providing overnight
polysomnography and sleep latency tests, mostly in
the diagnosis of sleep apnea .
t The' Pulmonary Function Testing Laboratory, using
spirometry, oximetry and other measurements to gauge

htPLICHIO . S FOR MEDIC \1 EDLCATIO

The changes taking place in the VA
system are also affecting clinical training programs at the University at Buffalo School of Medicine and Biomedical
Sciences. "From the educational point
of view, it's technically harder to set up
teaching activities for outpatients
because they come in, they're seen and
they leave," says Gerald Logue, MD,
vice chair for education in the school's
Department of Medicine. "That's a
challenge that the medical school is
faced with-not just at the VA , but
everywhere. Fewer and fewer numbers
of patients are being admitted to the
hospital these days. "
Logue, who is head of the Division of
Hematology in the Department of Medicine, served as chief of staff at the VA
until a year ago, so has experienced many
of the changes firsthand. Today, as director ofUB's residency program in internal
medicine, he's finding it a challenge to
give residents the kind of exposure to

patients they need while in training.
"Ward services have decreased and,
formerly, the provision of these services
was a very efficient means for teaching.
You have captive patients and a team of
students and interns taking care of them
and making rounds to see them as many
times a day as they care to. Because that
has obviously changed, we're now having to find ways to get the students
involved in specialty clinics and in freestanding or private offices and venues
that aren't part of the hospital setting.
Teaching that takes place in a clinic,
however , is more labor intensive
because you do a lot more one-on-one.
In a hospital, one attending can work
with a resident, a couple of interns and
a couple of students. In a clinic you can
just teach one person at a time. "

D

ue to logistics, such as long driving times, the teaching ofUB medical students at the VA currently
takes place at the Bailey Avenue

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location rather than at the community-based clinics, according to
Logue. Many students are assigned
to the facility's primary-care clinics,
and "virtually all UB medical students will at one time or another
have a rotation at the VA, " he says.
"For example, in third-year medicine, about one-fourth of the class
goes there for training. "
With regard to resident training,
Maddigan says , "We include the
resident clinics in our primary-care
services as much as we can. Our goal is
to help the residents train in a way that
best reflects what the real world is like,
so we very strongly emphasize with
them the management of chronic
disease and preventive health care.
"For the veteran , what they're
seeing looks seamless because they
have the same resident for three years,"
he adds. "In a way , our primary-care
clinics can be thought of as group
practices , with each having approxi-

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�. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . [1]
mately 8, 000 enrolled veterans. "
And as Logue notes, despite the logistical difficulties of matching physiciansin-training with clinic staff and patients,
the medicine being practiced in the
clinic settings is of the highest caliber.
"Generally speaking, the outpatient
experiences are evolving and, I think,
getting better and better," he says.
"When you bring a patient into the
hospital, you tend to have data overload

with test results and so on. In an outpatient setting, there's much less data.
You learn to depend more on the basics,
on taking the patient's history, doing a
clinical exam. In that sense, it's almost
back to basics-it's even better."
Whether it be patient care, facilities
management or medical education, the
challenges faced by Western New
York's VA Health care System are in
many ways no different from those

faced by the region's other health-care
systems. While each is driven by its
unique mission, history and
vision, the end goal for all is to discover ways to maintain the integrity of
patient care in as cost-effective a way
as possible. For the VA system, this
difficult end goal seems best grounded
in the "back-to-basics" approach
noted by Logue-no doubt, familiar
territory for America's veterans. +

Drug May Protect Against Hearing Loss
esearchers in University at Buffalo's Center for
Hearing and Deafness have shown for the first time
that a compound called leupeptin may help protect
against the noise-induced hearing loss caused by
living in noisy industrialized societies.
Using an animal model, the researchers found that
treating the inner ear with leupeptin before exposure to
high-level noise, comparable to a jet engine, reduced the
loss of sensory hair cells by 60 percent. Hair cells convert
sound waves into electrical impulses that are sent to
the brain.
Leupeptin, however, did not protect against the
damaging effects of the anti-cancer drug carboplatin that
can cause deafness in treated patients.
"The results are very exciting for two reasons. First, they
provide clues to the cellular events that lead to sensory-cell
death in the inner ear. Second, they suggest a potential
drug-therapy approach to protecting the ear against sound
damage," says Richard J. Salvi, PhD, lead investigator,
who is a professor of communicative disorders and
sciences in the College of Arts and Sciences, clinical
professor of otolaryngology and neurology in the School
of Medicine and Biomedical Sciences and co-director of
the Center for Hearing and Deafness.
Salvi and his colleagues at UB have been collaborating with Alfred Stracher and Abraham Shulman, both at
the SUNY Health Sciences Center at Brooklyn, to investigate ways to protect the auditory system from damage via
noise and ototoxic drugs, common causes of deafness in
Western societies.
Their current study-which was funded in part by a
$14,000 grant from the Martha Entenm~nn Tinnitus

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Research Foundation-was based on the knowledge that, in
many cases, degeneration of nerve function is caused by a
cascade of events, beginning with a trauma that induces an
increase of calcium in nerve cells. Excess calcium, in turn,
increases the level of enzymes called calpains, which promote the breakdown of proteins and other factors critical to
nerve functioning. "Drugs that inhibit the action of calpains,
of which leupeptin is one, have been shown to decrease
or prevent destruction of nerve functioning that results
in neuromuscular atrophy in cases of trauma or genetic
disorders," Stracher notes.
Salvi and colleagues set out to determine if leupeptin
also could protect the sensory hair cells in the ear from noise
and ototoxic drugs such as carboplatin-knowing that such
insults cause an increase in calpains--and thus prevent
hearing loss. The researchers treated the right cochlea of
chinchillas with leupeptin for 14 days. On the fifth day,
some of the animals were exposed to noise, at 100 decibels
or 105 decibels. The left ears of all animals served as
controls. Results from the noise exposure study showed
massive loss of hair cells in the ears not treated with
leupeptin, while only a few hair cells were missing in the
treated ear.
A similar study, designed to determine if leupeptin would
protect against hair-cell loss caused by carboplatin, showed
leupeptin offered no protection, Salvi says.
Other researchers on the study included Jain Wang and
Dalian Ding, research scientists in the Center for Hearing
and Deafness.
For more information on this study, refer to their recent
paper published in NeuroReport (Vol. 10, No. 4).

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Lifestyle Underpins Gallstones
he Western lifestyle of little
exercise, lots of saturated fat,
lots of refined sugar and little
fiber is a major risk factor for the
deve lopment of yet another
chronic disease- gallstones- a
new University at Buffalo study shows.
Published in the February 1999 issue
of the American journal of Clinical
Nutrition, the study is one of the few
popu lation-based investigations of
factors affecting the
development of gallbladder disease over time.
Results showed that
body mass index and
intake of refined sugar
and saturated fat were
directly associated
with the formation of
gallstones. The relationship between saturated fat and gallstones
was stronger in men than
in women . Conversely,
physical activity and a diet high in
monounsaturated fat, dietary cholesterol
and insoluble dietary fiber were protective against gallstones, results showed.
"This study confirms that gallbladder
disease is one of the diseases of Western
civilization ," says epidemiologist
Maurizio Trevisan, MD, professor and
chair of UB's Department of Social and
Preventive Medicine and author of the
study. "It's one more message that a diet
high in fat and refined sugar and a
pattern of low physical activity can get
you into all kinds of trouble. "
The results are interesting to epidemiologists, he says, because they
support the hypothesis that common
pathophysiological mechanisms may
underlie the chronic diseases afflicting
Western populations. Gallbladder
disease is increasingly common with
age and affects more women than
men. Twenty percent of women are

®

reported to have gallstones at autopsy.
The study was conducted in the small
farming community of Castellana in
southern Italy. In 1985 and 1986,
researchers administered ultrasound
scans of the gallbladder and took blood
samples from 1,429 men and 1,043
women selected randomly from the
population. Persons free of gallstones
at that time were reexamined by ultrasound between May 1992 and June
1993; they also completed questionnaires concerning sociodemographic

PARTICULARLY
INTERESTING WAS THE

F I ND I NG THAT SATURATED FAT

I NTAKE APPEARS TO HAVE A

STRONGER RELATIONSHIP TO

GALLSTONE FORMATION I N

MEN THAN IN WOMEN ,

TREVISAN SAYS .

status, medical history, dietary habits
and physical activity.
The 55 men and 49 women who had
developed gallstones during the study
period then were matched with controls
from the study population. To give a

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more complete picture of dietary intake,
these participants provided information
on how often they ate certain foods.
Analysis of the data from new cases
and controls showed that age, body mass
index (an indication of obesity) and
prevalence of diabetes were higher in
those who developed gallstones than in
those who did not, while physical
activity was lower. Dieting, caffeine and
smoking appeared to have little effect.
Dietary analysis showed that higher
monounsaturated fats and calories
expended lowered the
risk of gallstones,
while
higher
consumption of
refined sugars
and saturated
fat were directly
related to gallstone formation.
Particularly in-

~

teresting was the
finding that saturated fat intake
appears to have a
stronger relationship to gallstone formation in men than in women, Trevisan
says. Women had higher rates of gallstones at the first three quartiles of
saturated fat consumption, but theirrisk
increased slowly as consumption
increased. In men , however, the risk
doubled at each quartile of consumption; at the highest quartile, men were at
a higher risk of developing gallstones
than women.
"These findings seem to suggest that
other factors , such as hormones or
metabolism, may be more powerful risk
factors for gallstone formation among
women than saturated fat intake,"
Trevisan says.
The research team was headed by
Giovanni Misciagna, chief of the
laboratory of epidemiology and biostatistics at the Institute S. De Bellis in
Castellana. +

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Potatoes Deliver
Hepatitis BVaccine
an eating potatoes protect humans
against hepatitis B? Roswell Park
Cancer Institute (RPCI) and the
Boyce Thompson Institute (BTl)
at Cornell University began clinical trials in July I999 at RPCI to
test the safety and immunogenicity
of the world's first potential oral
vaccine against the hepatitis B
virus. Subjects will receive
the vaccine by eating potatoes genetically engineered
to contain it.
More than 2 billion
people worldwide are
affected by the hepatitis
B virus , a leading cause of
liver cancer and the cause
of more than I million
deaths annually.
Although an effective vaccine is available to prevent
hepatitis B, it is too expensive for developing nations to
afford . The vaccine must be
imported and refrigerated- at a
cost of$100 to $150 per personand three injections are required
over a six-month period, which prohibits mass immunization in Third
World countries.
The trial that began in July is the
culmination of several years of collaborative preclinical work by Yasmin
Thanavala , PhD , UB research assistant
professor of microbiology and professor and cancer research scientist in the
Department of Immunology at RPCI;
Charles Arntzen , PhD , president and
CEO of BTl and adjunct professor of
biological sciences at Cornell University ; and Hugh Mason , PhD, BTl
assistant research scientist and assistant professor of plant biology at
Cornell. The program is funded primarily by the
ational Institutes of

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Allergy and Infectious Diseases, part of
the ationalinstitutes of Health (NIH).
In previous pilot studies, researchers
inserted DNA extracted from hepatitis B
virus into tobacco leaves. An immunologically important protein antigen
known as HBsAG was partially purified
and injected into mice, where it elicited
the same immune responses as those

triggered by the commercial vaccine.
More recently, the researchers produced
this vital protein in potatoes that are
edible, making them more suitable for
testing oral vaccines.
In the current placebo-controlled,
double-blind Phase I study, health-care
workers who previously responded to a
licensed injectable vaccine receive an
oral booster dose delivered by a sample
of transgenic potato that expresses the
hepatitis B surface antigen. BTl generated the potatoes for the clinical trial
with financial support provided by Axis
Genetics of Cambridge, UK.
The clinical trial is coordinated jointly
by Thanavala and Martin Mahoney, MD
'95 , PhD '88, UB assistant professor of

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family medicine and director of the RPCI
Employee Health Clinic, who will be
responsible for conducting laboratory
testing and clinical assessment.
"We are very pleased to be taking the
next logical step with this research, "
Thanavala says. "The continued support of my basic research by the IH
and the World Health Organization,
along with the recent collaboration with
Axis Genetics , offers us a novel
way to impact public health and
control hepatitis B worldwide."
"This project is a wonderful example of moving
research ideas from the
laboratory bench to the
bedside," adds Mahoney.
"We are pleased to
participate in this trial to
bring this vaccine into a
clinical setting. "
Research with genetically engineered foods
opens up limitless possibilities for delivering vaccines, not only for hepatitis
B but also for such diseases
as malaria and leprosy. There
also may be a market for these
"garden variety" vaccines in
industrial countries. +
-

D EBORAH P ETTIBONE AND
C ATHERINE D ONNELLY

Hodgkin'sSmvivors Face
Second-Cancer Risk
ersons treated for Hodgkin's
disease in childhood are at high risk
for developing a second malignancy
and should be monitored closely by
their physicians throughout their
lifetimes , researchers at the
University at Buffalo and Roswell Park
Cancer Institute (RPCI) have shown
in two recent studies.

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Specifically, their findings showed
that persons treated for Hodgkin's
disease as children were at nine times
the risk of developing a second cancer,
with risks of developing certain types
of cancer much higher than that, compared to patients without Hodgkin's
disease. The risk of developing thyroid
cancer in males was especially high164 times that of controls. In addition,
the relative risk for breast cancer was
found to be eight times greater for
females; fornon-Hodgkin's lymphoma,
15 times greater for males and 23 times
greater for females; and leukemia, 19
times greater for males and 25 times
greater for female.
"These are big relative risks," says
Daniel M. Green, UB professor of
pediatrics, a specialist in pediatric
oncology at RPCI and senior researcher
for the studies. "These findings should
alert physicians to the need for careful
and continuing screening at a much
earlier age than the American Cancer
Society recommends for the population at large," he adds.
The studies involved 182 patients
treated at RPCI for Hodgkin's disease
between 1960 and 1989, all of whom
were less than 20 years old when
their disease was diagnosed.
By the time they were 30
years from diagnosis of
Hodgkin's disease, 2 7
percent of the patients
had developed at least
one second cancer, excluding skin cancer.
The second of the
two studies, which
reported on the incidence of skin cancer
only, found that the
most important variable was combined
treatment with radiation and chemotherapy. Of patients
who received radiation therapy alone,
3 percent developed skin cancer 20

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years after the diagnosis of Hodgkin's
disease compared to 5 percent of the
patients who received combined
therapy. +
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Gum Disease-Stroke
Relationship Found
he first national populationbased cohort study of periodontal disease and cerebrovacular disease, conducted by UB
researchers, has shown that people
with severe gum disease are twice
as likely to have the type of stroke
caused by blocked arteries than those
with good oral health.
The relationship of gum disease and
stroke was stronger even than the link
between gum disease and heart
disease, says lead author Tiejian Wu ,
MD, PhD, research assistant professor
in the Department of Social and
Preven tive Medicine in the School of
Medicine and Biomedical Sciences.
"This is the first major study to look
at this question," says Wu. "There have

been a few other very limited studies,
but the number of subjects was small
and was drawn from restricted populations. This study also looked at subgroups- men , women , blacks and
non-blacks. Periodontal disease was
associated with an increased risk for
cerebrovascular disease in all groups."
The study cohort comprised 9,962
adults between the ages of 25- 75 who
took part in the first National Health
and Nutrition Examination Survey
( HA ES I) conducted from 1972 to
1974anditsfollow-up, which was completed in 1992. Respondents' oral health

THE

RELATIONSHIP

OF GUM D ISEASE AND

STROKE WAS STRONGER EVEN

THAN THE LI NK BETWEEN

GUM DIS EASE AND HEART

DISEASE, SAY S LEAD AUTHOR

TIEJ IAN W U , MD , PHD .

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was categorized as no periodontal
disease , gingivitis, periodontitis, or
toothless , based on information
collected during HANES I.
Cerebrovascular-disease events
were confirmed in the follow-up
survey through hospital records and
death certificates. Results showed that
periodontitis was a significant and
independent risk factor for developing cerebrovascular events and for
non-hemorrhagic stroke- loss of
blood flow to the brain due to a blockage rather than a burst vessel.
Periodontitis was associated with a
twofold increase in non-hemorrhagic
stroke risk . The study found no
association between periodontal disease and hemorrhagic stroke or TIA.
According to Wu, periodontal
disease is thought to increase the risk
of stroke in much the same way it
increases the risk of heart attack.
"Bacteria, endotoxins and other bacterial products from gum pockets enter
the circulation and may promote an
inflammatory response , causing cells
to proliferate in the blood vessels and
causing the liver to increase production of clotting factors. Bacteria may
also attack the vessel lining and
damage endothelial cells ," he says.
"Further, several periodontal pathogens can induce platelet aggregation
and may promote plaque formation that
can cause blockages and clotting. "
Maurizio Trevisan, MD , professor and
chair of the Department of Social and
Preventive Medicine and the study's
coauthor, says, "While more studies
are needed for a conclusive statement
about the cause-and-effect association,
the consistency of the findings in different gender and racial groups , and
the strength of the association between
two chronic conditions prevalent in
the adult population, may have important implications for individual and
public health. " +
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CERTAIN PHYS ICAL

CHARACTERISTICS

LI NKED TO H IGH

LEVELS OF

TESTOSTERONE-

THE MOST ACT IVE

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HAVE A GREATER
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R ISK OF DEVELOP I NG

BREAST CANCER THAN

WOMEN WITHOUT

THESE CHARACTER IST ICS .

Breast Cancer Risk
and Insulin Levels
aola Muti, MD , PhD, University at
Buffalo epidemiologist and
assistant professor of social and
preventive medicine, has received
a two-year $238,000 grant from
the United States Army Medical
Research and Materiels Command to
conduct the first major study of the
relationship between breast cancer risk
and levels of insulin in the blood.
She also will investigate breastcancer risk and its association with levels of male sexual hormones, or androgens; female sexual hormones; and insulin-like growth factor 1 (IGF-I) ,
a protein that promotes changes in
breast cells.
Muti, who has been researching the

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role of hormones in the development of
cancer, has shown in an earlier study
that women with certain physical
characteristics linked to high levels of
testosterone- the most active androgen- ma y have a greater risk of
developing breast cancer than women
without these characteristics.
Her current study, which builds on
her previous research , aims to show
that the risk of developing breast cancer is associated with the hormonal
conditions of increased insulin levels
in the blood; increased bioavailability
of IGF-1 ; increased levels of androgens-specifically, total and free testosterone; and increased levels of estrogens-specifically, total and free estradiol. Finally, Muti hopes to show that
the increased bioavailability of IGF-1
and the higher concentrations of the
sexual hormones are caused by the
higher insulin levels.
Teresa Quattrin, MD , UB associate
professor of pediatrics and director of
the Diabetes Center at Children's
Hospital , and the Italian ational Cancer Institute in Milan are collaborating
on the study. +
-LOIS

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lfij
expected as managed-care physicians to
be knowledgeable and efficient providers of health care- supplying appropriate medical services, maximizing the
utility of patient contact and maintaining quality patient care. And we are expected as physicians in the community
POLITICS IS AN ANSWER
to be sensible and judicious members of
society- remaining nonjudgmental and
understanding, being sensitive to every
HREE YE-\RS AGO I BEGA to have a gnawing feeling in my person's predicament and valuing the
health of the community above all else.
stomach. The sensation was not a pain that might lead me to a These expectations are severe by any
estimation, but they are reasonable.
physician's office for a checkup or to my medical texts for causal
"The glory days of American medicine"
is a phrase that's come to represent
insight. Instead, it was a feeling of disappointment.
the era where a Marcus Welby- type
At the time, I was living in Tucson , of 20 years ignorant of the status of physician could practice medicine
Arizona , and working on an epidemio- health care as a privileged commodity. independently, concerned only with
logical project seeking to discern the The son of a pharmacist, I was raised in a the patient's best interests . While
relationship between physical activity reasonably wealthy home, where health society's expectations for a primaryand chronic disease in postmenopausal care and medical information were never care or specialty-care physician were
Hispanic women. The disappointment wanting. Like everyone else, I had been similar then to what they are today,
began one day while I was driving back inundated with statistics detailing the they were different with respect to the
from Phoenix, where I had met with the fact that 42 million people in the United community physician.
state's project coordinators for the study. States (or 25 percent of the population)
Free care, or care at appropriated costs,
I should have felt great. I was 22 years are uninsured. Yet what I began to was both a common and anticipated
old and living in one of the most beau- realize, as I thought about the women practice many doctors used to ensure
tiful regions of our country. I had been enrolled in the Arizona study, was that and improve the health of the commugood health is each person's nity. In addition, prestige was inherent in
accepted to medical school
at the University at Buffalo
greatest need and that health the practice of medicine. Physicians were
and would begin classes in
professionals are just as respected members of the community.
responsible for the health of They were asked to serve as public
six months. And I was on
vacation (being away from
the community as they are officials and were role models for prosschool and working on public health for that of the individual.
perity in the United States.
projects is certainly a vacation for me) .
As medical students, we are challenged
Today, however, in the era of manBut all I could think about during to meet the needs of our future patients aged care, a physician's ability to fulfill
that 110-mile drive through the desert in spite of the changing U.S. health-care the community's expectations seems
were the women enrolled in our study. system. We are expected as primary-care compromised. Gone are the opportuniThey did not agree to participate physicians to be diagnostic and rational ties to provide independent free care,
because they were interested in further- at the first moment of patient-physician replaced by utilization review and capiing research or because they had time contact-limiting preventable disease, tation. Gone are the prestige and proson their hands. o. The majority of the reducing unnecessary distress and im- perity of medicine, replaced instead by
women participating in the study were proving patient health. We are expected the business and entertainment indusdoing so because it provided them with as specialty-care physicians to be profi- tries . Gone is the physician as a role
health-care services for that short span cient and expedient when consulted on model for success, replaced instead by
of time. Access to health care, I was cases of advanced disease-assessing the the independent consultant or computer
beginning to realize, was a privilege best plan for treatment, working in technologist. But physicians should
most of them did not have.
cooperation with the primary physician not be discouraged: They are still of
Until that time, I had spent upwards and improving patient health. We are considerable importance to the society.

Health-Care Policy:
To Treat or Not to Treat

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�Last April , I attended a three-day
political leadership training workshop
in Washington, DC, that prepared medical students to become successful advocates for the public's health. At the Political Leadership Institute, we were
taught how to design a political strategy, research an issue, write a position
paper or an editorial for submission
to an advocacy
group or newspaper , speak in
public and lobby a
public official. The
weekend , which
was sponsored
by the American
Medical Student
Association , was
so bus y that I
didn't even have
time to see the
sights of our
nation's capital!
Instead, I learned
how my actions as
a medical student, and eventually as a
physician , can affect the health of
my community.
It may seem insignificant, but the
dues paid to a medical organization
supplement its office of legislative
affairs. That organization may one day
be instrumental in convincing a senator

Physicians must not diminish the
political power that is inherent in their
profession by being nonparticipants in,
or even apathetic to , health-care policy
making. Their patients cannot afford it.
Despite the image doctors have of being
detached from politics, in reality they
have always played a significant role in
the political process. Five doctors
signed the Declaration of Independence. Before the
Civil War , there
were about 20
doctors in every
Congress; after the
war , individual
political participation dropped ,
but
physician
power
stayed
strong through the
formation of organizations like the
American Medical
Association , the
American Medical Student Association
and the Association of American
Physicians and Surgeons, all of which
represent physicians in the political
arena . Why have physicians always
continued to participate in politics?
Political affairs affect the health of
the community.

I

E-TESTING CONTINUED FROM PAGE

10

popped up right in front of me, I clicked a button and
I was done. "
When Duff had finished his exam, his study partner, Christopher Adams, still had four days before he sat down to his test.
"We had really been pushing each other, and the camaraderie
was great," Adams says. "You couldn't sleep in because that
person was waiting for you. You couldn't leave the library early
because that person was counting on you . After Mike [Duff]
took his exam, I felt like I hit a wall. Your jokes just aren't as
funny when you're telling them to yourself. "

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to introduce significant tobacco reform
legislation. Participating in a voterregistration drive is time consuming;
however , publicizing key political
issues and convincing fringe voters to
cast their ballots may elect a state representative who supports universal access
to health care. Writing a thoughtful and
informative editorial on breast cancer
for the local paper may help the community better understand, prepare for , or
prevent a disease that over 184,000
women are diagnosed with each year.
Similarly, lobbying a city council for
increased funding for community
clinics may help limit the spread of
infectious disease.
Three years ago, I could see no
reason why so many middle-aged women
were participating in an epidemiological
study except for the express purpose of
obtaining health-care services. I can still
see no other reason, but I hope that my
actions eventually will provide those
women with health-care privileges. As an
advocate for the public's health , my
participation-every physician's participation-in legislative affairs improves
the health of the public. As health professionals, we must remember that we are
just as responsible for the health of the
community as we are for the individual. +
josLpli S. Ross is c th . -d-) a su.c L • c:. ••.• L
Unhcrsil) at Buffalo ~clwol of \lcdicinc and
Bwmcdical SCiences .

As e-testing makes its mark on a new generation of
students one thing is certain: The new format has profoundly changed the experience of taking a standardized
exam. With literally hundreds of exam dates available, gone
is the shared misery of hundreds of students huddled over
test booklets. Gone, too , is the room monitor telling students
when to take a break. Now, the computer does that for them.
For his part, Adams isn't the least bit nostalgic about the old
days. He'll take the mouse over the pencil any day. But in this
brave new world of test taking, he may do well to ensure that
his next test date coincides with his study partner's, because
there's still no replacement for camaraderie. +

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�BY

L I N D A

J .

ATrue Story

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"I don't go out much and
really can't plan to have dinner with you .... Well I guess
you can come see me, so long as you promise not to talk
about money ... "
I had been at the University at Buffalo for less than a
year and was traveling to her city for a professional meeting.
I decided to meet some of our past donors and thank them for
what their gifts had made possible. In her case, she and her
husband (deceased) had established a modest scholarship
endowment several years earlier. There was no additional
information on file so I checked the current value of the
endowment (credible growth), the number of students who
had received scholarships, and off I went.
She, her cats and I had lemonade by her pool and talked.
She told me about her family-"a single and two sets of
twins"; her husband and his early practice; and the vacations
with five kids and a tent. She also showed me pictureschildren, grandchildren and pets, trips they had taken, and
friends. She told me she volunteered at a local senior citizens'
center during tax season to help others with their taxes. In
her eighties, she expressed amazement that so many of those
"old people" didn't know how to fill out their tax forms.
When dinnertime rolled around, she smiled and said she
would join me after all, if the offer were still open. At a nearby
restaurant, we continued the conversation. She talked about
the heartbreak of watching her beloved husband lose track of
who she was and, then, who he was. She talked about her
dream of seeing a day when the mysteries of Alzheimer's
Disease were understood and there were options to slow or
halt its progress, and preventive measures to keep it at bay.
A week or two later, I sent a brochure developed by the
chair of nuclear medicine, for he, too, had a dream- using
marked neurons to visualize the activity of the brain. A
relatively new diagnostic tool at the time, Positron Emission
Tomography (PET) was used at only a few centers in the state,
to study the secrets of brain physiology and to diagnose
various conditions that didn't show up with other types of
technology. This crazy dreamer wanted UB to build one.
That was nearly ten years ago. In the intervening time, she
and I developed a long-distance friendship, a definite fondness and appreciation, each for the other.
During one conversation she said, "My husband and I
never complained about paying taxes. He earned a good living

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Buffalo

C 0 R DE R ,

PH D,

C F R E

and that's our country's way of paving the roads and providing schools for children. It was fair and we didn't mind that
much. But, I don't want to give away half of our hard-earned
resources when I die. My children will share the amount
that's excluded from taxes. Now, help me figure out how to
arrange the rest so Uncle Sam won't get any."
This woman knew she had the means to make an impact
"somewhere." She wanted to make a difference in the understanding of Alzheimer's Disease. She believed that UB's
proposed center was a way to "light one little candle against
the dark."
The department chair tirelessly made enthusiastic presentations to anyone who would listen, which painted a picture
of what that type of research center could be. Using PET
scanners, he explained, researchers might slowly uncover the
secrets of how human brains process information and what
happens when they lose that ability to function.
She became captivated by the convergence of those dreams.
Her creative planned gift, a charitable trust that would eventually fund an endowment for the
PET Center, his negotiations involving the school's partnership with the
Veterans Administration, a combination of other funding sources and
additional private gifts made the
building of the PET Center possible.
The center was completed while
she was still able to maneuver easily.
She was present at its grand opening,
along with her oldest daughter. She
helped to unveil a modest plaque
commemorating her husband's life and her commitment to
this center. After the dedication, her daughter made a rubbing
of the plaque. It was copied for all her children and then
framed and hung in her living room.
Her charitable trust reached maturity this past summer.
ow, there is a major endowment bearing their names that
will keep her dream alive and similar research moving forward, forever. My friend died peacefully, at age 93, with her
oldest daughter again by her side.
Her last act of generosity was to have a vital portion of her
brain removed immediately following her death and conveyed to a group of Alzheimer's researchers at one ofHarvard's
affiliated hospitals. She was then buried next to her husband
back home in Buffalo. What is essential lives on, in those of
us who knew her and cherish her memory-and in the future
research that her endowment will make possible.
CONTINUED ON PAGE 31

Physician

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�Endowments of the School of Medicine . di al S.
1ome c c1ences
HE SCHOOL'S E DO\\.-NlENT IS COMPRISED OF DOZE. S of separate funds, many named for the
individual or couple who initiated them. Collectively, they provide valuable resources that enrich
the lives and academic experiences of students, faculty and staff, and the wider community in our
region. They provide scholarships, annual lectures, underwrite research and travel to present
research results. Endowed chairs strengthen individual departments and the school as a whole.
Visiting professorships bring the students into contact with nationally known professors who spend
a day or several days on campus.
We have a strong endowment. We need to expand it. The
difference between a great institution and one that is
merely adequate is often found in the size and strength of
the endowment.
Listed below are the school's endowments. Those listed in
bold received additional gifts this past fiscal year. Those with an
asterisk (*)were established between july 1, 1998, and] une 30,
1999. Those with both an asterisk and bold lettering were
initiated and at least partially funded during that time period.

Gifts to the school may be designated for any existing
endowed fund. New endowments that meet funding guidelines established by the university may be established at any
time. Please give me a call if you have questions, notice an
inaccuracy or would like to make arrangements for a new
endowment in
your name or in '
Linda J. Corder (lyn) is the associate dean and director of
honor of somedevelopment. She may be reached toll-free at 1 (877)
one you admire
826-3246. Her e-mail address is ljcorder@buffalo.edu.
or love.
I

H.W. Abrohmmer Memorial Scholarship
Sidney Addleman Memoria l

Dr. and Mrs. Joseph A. Chozon Medical Scholarship

Dr. George J. Alker Fund for Neurodiology

Clinical Preventative Medicine Fellowship

Theodore &amp; Bessie G. Alpert School of Medicine Scholarship

Almon H. Cooke Scholarship

Alpha Omega Alpha Library Fund

Patrick Bryant Costello Memorial

Alpha Omega Alpha Endowment

CTG Oncology Fund

American Academy of Family Physicians President's Award

James H. Cummings Scholarship

Deportment of Anatomical Sciences Library Fund

Edward L. Curvish M .D. Award

Anesthesiology Deportment Endowment

The Elizabeth Medical Award

Bocceelli Medical Club Award

Dr. Robert M . Elliot Scholarship

L.B. Badgero Medical School Fund

Eleanor Fitzgerald Fairbairn Scholarship

Wolter Barnes Memorial Scholarship

Family Medicine Endowment

•virginia Barnes Endowment

Feyler Fund for Research in Hodgkins Disease

Dr. Charles A. Baudo Award in Family Medicine

Dr. Grant T. Fisher Fund

Thomas R. Beam, Jr. Memorial

L. Wolter Fix, M.D. '42/'43 Endowed Scholarship

Dr. Robert Benninger Fund in Orthopaedics

Edward Fagan Memorial Prize

Robert Berkson Memorial Award in the Art of Medicine

Ford Foundation for Medical Education

Museum of Neuroanotomy Fund (Bernhoft-DeSontis Library

Thomas Frawley, M .D. Residency Research Fellowship Fund
Marcos Gallego, M.D. Clinical Excellence Fund

Fund Anatomy, Cell Biology and Neurobiology)

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Louis J. Beyer Scholarship

James G ibson Anatomical Prize

Paul K. Birtch M.D. Fund

Wolter S. Goodale Scholarship

Dr. Solomon G. Booke and Rose Yosgur Booke Fund

•trene Pinney Goodwin Scholarship

James H. Borrell Urology Fund

A. Conger Goodyear Professorship of Pediatrics

• Anne and Harold Brody Lecture Fund

George Gorham Fund

Clayton Milo Memorial

Dr. Bernhardt S. and Dr. Sophie B. Gottlieb Award

George N . Burwell Fund

• carl Granger, M.D. Endowment

Dr. Winfield L. Butsch Memorial Lecture in Clinical Surgery

Dr. Pasquale A. Greco Loon Fund

Vincent Capraro Lectureship Fund-class of 194S

The Glen E. Gresham, M.D. V isiting Professorship

Dr. Charles Cory Memorial

Dr. Thomas J. and Barbaro L. Guttuso Scholarship &amp; Award

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ENDOWMENTS CONTINUED FROM PAGE

Omega Upsilon Phi Chi Scholarship

31

Josephine Hoyer Orton Trust Fund
Victor A. Panaro Medical School Fund

F. Corter Ponnil, Jr. , M.D. Award Endowment

Gynecology-Obstetrics Department Endowment

Stephen J. Paolini, M .D. Memorial

Jean Sarah Hohl Memorial

•Parkinson Research Fund

•Eugene J. Honovon Scholarship

John Paroski Memorial Award

Florence M. &amp; Sherman R. Hanson Fund for

Robert J. Patterson Resident Award

Medical Education

Dr. Mark Pettrino Memorial

DeVille V. Harrington Lectureship

Primary Care Achievement Fund

The Hekimion Fund

Progressive Medical Club of Buffalo Fund

Hewlett Family Enrichment Fund for Psychiatry

Psychiatry Department Endowment

Charles Gordon Heyd Medical Resources Fund

Dr. Hermon Rohn Memorial Lecture t

Dr. Fronk Whitehall Hinkel Scholarship

Albert and Elizabeth Rekote Choir in Cardiovascular Disease

Rolph Hochstetler Medical Research Fund

Albert C. Rekote Rehabilitation Medicine Library Fund
Donald Rennie Prize in Physiology

Abraham M. Horowitz Fund
R.R. Humphrey &amp; Stuart L. Vaughan Scholarship
James N. Johnston Scholarship

Douglas Riggs Award in Pharmacology and Therapeutics
The Ring Memorial Fund

C. Sumner Jones Library Fund

Emile Rodenberg Memorial Award

Harry E. and Loretto A. Jordon Fund

Thomas A. Rodenberg and Emile Davis Rodenberg

H. Colvin Kercheval Memorial

Scholarship
Elizabeth Rosner Fund

Dean Stockton Kimball Scholarship
Dean Stockton Kimball Memorial

Ira G. Ross Chair of Medical Informatics

Dr. James E. King Postgraduate Fund

Dr. Sheldon Rothfleisch Memorial Fund

Morris Lamer and Dr. Robert Bernat Scholarship

Harold S. Sones and Thelma Sones Medical Scholarship

Dr. Charles Alfred Lee Scholarship

Philip P. Song Memorial Fund

Dr. Garro K. Lester Student Loon

Sorkorio Family Endowed Choir in Diagnostic Medicine Fund
Schafer Fund in Cardiovascular Diseases

Lloyd Leve Fund
The Lieberman Award
Hans Lowenstein Award

Scholarship of the Progressive Medical Club of Buffalo
School of Medicine and Biomedical Sciences Unrestricted

Lupus Scholarship Fund

Endowment

William E. Mabie D.D.S. and Grace S. Mabie Fund

Lillie S. Seel Scholarship

Dr. William H. Monsperger Fund

Irene Sheehan Fund
Dewitt Holsey Sherman and Jessica Anthony Sherman Fund

Claro March Medical Scholarship
Medical Alumni Endowed Scholarship

Dr. Lois A. and Ruth Siegel Teacher' s Award

Annual Participating Fund for Medical Education Endowment

S. Mouchly Small, M.D. Award in Psychiatry

Medical School Lectureship

•s.

Medical School Closs of 1957 Scholarship

Mouchly Small Education Center Fund

•Irvine and Rosemary Smith Chair in Neurology Fund

Medical School Class of 1958 Scholarship

Dr. Irving M. Snow Fund

Medical School Class of 1963 Scholarship

•Mary Rosenblum Somit Scholarship

Medical School Closs of 1973 Scholarship
Marion Mellen Fund

Morris and Sadie Stein Neuroanotomy Prize
John H. Talbott Visiting Scholarship

•Microbiology Memorial Fund

Trevett Scholarship

Dr. David Kimball Miller Award

Richard E. Wahle Research Fund

Eugene R. Mindell, M.D. Choir in Orthopeoedic Surgery
G. Norris Miner, M.D. Memorial Award

Mildred Slosberg Weinberg Endowment
E.J. Weisenheimer Ophthalmology Award

• philip D. Morey Scholarship

Dr. Mark Welch and Beulah M . Welch Scholarship

Richard Nagel, M .D. Anesthesiology Research

• James Platt Wh ite Society Endowment

Dr. Anges S. Naples Memorial Scholarship

Williams /Bloom Medical Research Fund

The Dr. S. Robert Narins Memorial Award

Dr. Morvin N. Winer Fund for Dermatological Research

Notional Medical Association (Buffalo Chapter) Scholarship

Witebsky Fund for Immunology

Naughton Endowment

Dr. Ernest Witebsky Memorial

•Nephrology Research Endowment

Forney R. Wurlitzer Fund

Dr. Erwin Neier Memorial

Dr. Mark Zaleski Award

Antoinette and Louis H. Neubeck Fund

Hermon and Rose Zinke Scholarship

Neurology Deportment Endowment
Dr. Benjamin E. &amp; Lila Obletz Prize Fund in Orthopaedic Surgery

l·udou·mcfztS
1 udoumem,

Dr. Elizabeth P. Olmsted Fund in Biochemistry

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�Dear Fellow Alumni,
l T \\AS ~1Y HO'\OR TO SPEAI\. AT THE \.1EDICAL SCHOOL\ ORIL 'T \-:-'0

for the
first-year class on October 9, 1999, in Butler Auditorium. During that time, I
introduced the class to the Physician-Student Mentoring Program, in which the
Medical Alumni Association pairs up each medical student with a community
physician in a nonacademic advisory role. We are optimistic about this program
and are pleased to announce that we received a sufficient number of physician
volunteers this year to match all students.
Later that day, I was also pleased to take part in the White Coat
Ceremony that was planned by Dr. Tom Flanagan and reported on in
this issue of Buffalo Physician (see page 12). It was a wonderful program
that will be expanded next year, and I urge anyone interested to feel free
to attend.
In mid-September the Past Presidents' Dinner of the Medical
Alumni Association was given in honor of Robert E. Reisman, MD '56,
recipient of the 1999 Distinguished Medical Alumnus Award. Bob's
receipt of this award, which will be reported in the next issue of Buffalo Physician,
was prompted by a wonderful nomination fromjerome Kassirer, MD '57, former
editor-in-chief of the New England journal of Medicine. We on the Governing
Board were so pleased to be able to give Bob this award.
Spring Clinical Day is being organized by Colleen Mattimore , MD '_9 1,
and our Stockton Kimball lecturer will be Maxine Hayes, MD '73. Dr. Hayes is the
assistant secretary of community and family health for the Washington State
Department of Health, where she oversees a staff of more that 200 and manages
an annual budget of over 300 million dollars. Early in the Clinton Administration ,
Dr. Hayes was on a short list for the Surgeon General post
There was an out-of-town reception in San Francisco on October 12,
1999, at the American College of Surgeons' 85th Annual Clinical Congress. The
Medical Alumni Association co-sponsored a reception in conjunction with the
Department of Surgery at this meeting. All alumni attending this meeting and
alumni living in the area were invited to a reception at the Renaissance Park on
October 12.
The Community Physicians Speakers Program will be starting up this
falL This is a very well received program in which the Medical Alumni Association
arranges for physicians in the community to come and speak to the first- and
second-year classes during lunch to discuss the lifestyles of the various
subspecialties. The Medical Alumni Association provides pizza and soft drinks
for the talks.
The Medical Alumni Association partially sponsored a party held for
the first-year class on August 12, 1999, on the USS Little Rock. This event provided
a good opportunity for Dr. John Bodkin, Dr. Bertram Portin and me to meet and
welcome members of the class.
Finally, we are seeking nominations for next year's Distinguished
Medical Alumnus Award. (See nomination card inserted in the inside back cover
of each Buffalo Physician.) As a reminder, your nominations must be received by
March 1, 2000.

Richard L Collins, MD

President, Medical Alumni Association

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JOHN E . SH I E L DS JR ., MD '68 ,

Ham L. Metcalf, MD '60

writes: "Relocated to Hampton
Bays, Y. Wife, Bernice, has pro-

Receives Berkson Memorial Award

gressive MS. Prime Care of
Hamptons. FAA consultant. GD
consultant. Addiction medicine
consultant. "

arry L. Metcalf, MD '60, clinical professor Department of Family Medicine, in presenting the
of family medicine at the University at award to Metcalf, noted that he has acted as an
Buffalo, is the recipient of this year's advocate for continuing and comprehensive patient
RobertS. Berkson, MD, Memorial Award careboththroughhispracticeandinthemedicalsystem
in the Art of Medicine. Dr. Berkson was that has evolved to serve patient needs.
- - - - loved by his patients, respected by colA politically active physician, Metcalf has effecleagues and students, and his special
--lively implemented programs and
expertise in the "Art of Medicine" is
enacted initiatives for the advancement
meant to be perpetuated by this award.
of medical education and patient care at
state and federal decision-making levels.
For over thirty years, Metcalf has
been committed to educating graduate
The award also recognizes that Metcalf
"is well respected by his physician
and postgraduate students in the art and
science of medicine, a commitment that
colleagues and medical students and,
has been enhanced by his strong role
most importantly, by his patients, whom
modeling as a physician and the respect he has he continues to serve in a compassionate and caring
garnered for his abilities in patient care.
manner that indeed elevates his practice of medicine
Dr. Thomas C. Rosenthal, professor and chair of the from a science to an art."

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HUBBARD K . MEYERS , MD '36 :

writes: "I participate in the
retired physicians journal Club,
which meets biweekly in Green
Valley, AZ. The club has 30
members from various states and
areas of specialities, including:
dermatology, internal medicine,
general practice, surgery ,
orthopedics, anesthesia, neurology and psychiatry.

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LEONARD R.SC HAE R , MD , '55 ,

writes, "Since retirement in 1991,
I have been involved in mostly
volunteer activities. (!even volunteered for a coronary bypass
in 1996.) I have been a docent at
science museums, lecture to high

®

school senior boys regarding
testicular cancer, serve on the
advisory board of Emeritus College Division of Diablo Valley
College. I have
taken many
adult education classes as
well. Latest
hobby: have
had supporting
roles in a couple of movies,
including Bicentennial Man,
starring Robin Williams, and
SF0-2000, starring Timothy
Hutton. Both will be released
near the end of the year. Mostly
I enjoy my two precious
granddaughters, Danielle and
Talia , who live 10 minutes
away! Send e-mail! nanapop@
hotcoco.infi. net

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MD '74 ,

R U SS ELL,

writes: "Elected president of the
American Society of Neuroradiology (ASNR) for 1999- 2000;
program chair for the AS R
annual meeting in San Diego in
May 1999, with 3,000 attending;
member of the editorial boards
for the American Journal of
Neuroradiology and Radiology; a
member of the executive council
for the Society for Cardiovascular
and lnterventional Radiology. I
also am a regional member of the
UB Medical Alumni Association
board. My wife , Sandra K.
Fernbach, MD, and I have two
daughters: Gabrielle Robin, 16,

s

J OH N . J . L A MAR JR . , MD '63 ,

and Meredith jean, 12.

writes: "Retired as of October 1,
1998. Have 2 1/ 2 grandchildren.
Must visit Ft. Hood to see our

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K EVI N FEREN TZ, MD '83 , writes:
"I have been awarded the
Exemplary Teaching Award for
full-time faculty
from theAmericanAcademy of

current grandchildren and their
parents. Doing lots of fishing
and gardening."
B E RT W . RAPPOL E, MD '66, has
been elected to a two-year term as
president of the Eighth District
Branch of the Medical Society of
the State of ew York. Rappole, a
surgeon in jamestown, NY, is past
officer of the
District Branch

Family Physicians.! received
the award in
Orlando, FL, at
the Congress of Delegates meeting in September 1999. I've been
in Buffalo several times over the
last year, giving lectures on
smoking cessation to practicing
physicians. It's always good to
come back."

and a past president of the
Chautauqua
County Medical Society.

Physician

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•
•

MARC LEVINE , MD '83, writes:

P HI LOMENA MUFALLI BEHAR,

"My wife, DEBBIE FELDHEIM

Johnson Foundation on a sur-

MD '92, writes: ')erryandibought

I

early 1950s, serving at Thule Air
Force Base in Greenland. From

[MD '84] and I recently cele-

veillancesystem

a home in Memphis, TN, in May

1953--1973, he practiced medicine

brated our fifteenth wedding

for tracking to-

1999. I completed a two-year

inl.ockportand was Niagara County

anniversary. We live in the

bacco control

pediatric otolaryngology fellow-

health commissioner from 1973

Maryland suburbs of Washing-

activities in the

ship in Atlanta in June 1999 and

until his retirement in 1983. Clifford

ton, DC, with our three chil-

United States.

dren: Sammy,Max and Jeremy,

The goal of the initiative is to

am currently in private practice.
Jerry works for Thomas and Betts

was a fellow of the Royal Society of
HealthinEnglandandoftheAmeri-

age 4, 6 and 8. We both gradu-

identify policies that are effective

as their director of transportation.

can College of Surgeons.

ated from the Washington

in reducing adolescent tobacco

Psychoanalytic Institute several

use. Prior to coming to RPCI,

years ago and have private

Giovino was with the Centers for

practices in psychiatry and

Disease Control in Atlanta, GA,

psychoanalysis. In addition to

where he was Chief of the Epide-

time spent raising our three busy

miology Branch of the Office on

boys , we are active in the

Smoking and Health.

psychoanalytic community and

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GALE BURSTEIN AND P ETER

ROBERT LASEK AND COLETTE

BLOOM , MDs '90. Gale writes:

PRUEFER LASEK, MDS '84, write:

"Peter and I moved to Atlanta,

"We are happy to announce the

GA, in June. I am a medical epide-

birth of Eric Colin Lasek on April

miologist at the Division of Adolescent and School Health at the

7, 1999. We left our practices at
Geisinger Medical Center for op-

Centers for Disease Control. Peter

portunities in Plano, TX, lastJuly.

is an assistant professor in the GI

Hello to all our friends. Sorry we

Division at Emory Medical School.

couldn't make the reunion."

MICHAEL K. LANDI , MD '94, and his wife, Antonietta, announce

Our son, Zachary,just turned one
DEBBYAND WALLACE S ALTER,
MDs '85, are living in Grand
Junction, CO, with their three
children, Jeremy, 12, Brittany,
10, and Garrell, 8. They practice
family medicine together and
have started the area's first
multispecialty group with family medicine, internal medicine
and

OB-GY -Columbine

Medical Associates.

the birth of their daughter, Lily Marie, on july 21, 1999. She

year old in August. WeseeLAURIE
BURTO N, MD '90, very fre-

weighed 5 pounds, 12 ounces. Mom and baby are doing great!

quently. She is a pediatric/ER doc
at Egleston Hospital and assistant
professor of pediatrics at Emory
University." E-mail: gibs@cdc.gov

IN MEMORIAM
FRANCIS J . CLIFFORD, MD '42,

lLANA FEI NERMAN , MD '93,

professor emeritus of anatomy at
UB's School of Medicine and Bio-

writes: "After completing my oto-

medical Sciences and a former

in

iagara County commissioner of

Boston, MA, inJune 1998, Cary,

health, died May 17, 1999, in

laryngology

residency

Lockport, NY, after a lengthy ill-

GARY GIOVINO, PHD '87, has

Jeremy and I tried relocating to
ew Jersey. However, we soon

joined the faculty at Roswell Park

realized that Massachusetts was

ationfrom UB, Clifford served twice

Cancer Institute (RPCI) in the

more our speed and are now set-

as an Army physician. During

Department of Cancer Prevention,

tling down in Dartmouth, MA.

World War II, he was stationed in

Epidemiology and Biostatistics. He
is responsible for leading a project

Jeremy will be five years old this
October and his brother/sister will

orthem Europe with the 83rd
Infantry Division and was ordered

funded by the Robert Wood

hopefully arrive in September.

to active duty again during the

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THOMAS

J.

MURPHY, MD '45,

died June 1, 1999, in Syracuse,
Y, at age 76. Murphy was born
in Binghamton, NY, and attended
otre Dame University prior to
attending UB's medical school. He
was an internist for 40 years and a
clinical professor for medical students at St. Joseph's Hospital in
Syracuse. He was a past physician
for Le Moyne College and a consulting staff physician at the Syracuse Developmental Center, Plaza
Nursing Home and St. Joseph's
Hospital. Survivors include his

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I

his Snyder home after a lengthy
illness. He was 85. In addition to
conducting a private practice ,
Link was chief pediatrician at Sisters Hospital, where he also was

wife, Theresa M. "Hunnie," six
daughters and two sons.
SAMUELP . AVERSANO , MD '49 ,

died on May 16, 1999, in Rochester, Y. Aversano was a native of
Rochester, attended Madison
High School and Syracuse University, where he graduated with
a BS in chemistry. He was in the
U.S. Army at Pearl Harbor when

president of the staff in 1967-68.
Until his retirement in 1987, Link
worked extensively with disabled
children. He was physician-incharge at the Erie County Health
Facility for Children and School

it was bombed at the beginning
ofWWli and he received an honorable discharge in 1945. Fol-

84, and the new School 84 was
dedicated in his honor. He was
clinic medical director for the

lowing graduation from medical
school, he completed his postgraduate training at the then E.J.
Meyer Memorial Hospital in Buffa lo. He spent his professional
life in Rochester, where he was in
solo general practice for 15 years
before becoming associate
medical director of St. Ann's
Home for the Aged, a position
from which he retired in 1987.
He is survived by his wife, Mary
Aversano, and by his son, Thomas, of Baltimore, MD.
ROBERT T . DEAN , JR , MD ' 55 ,

d ied of lung cancer on May 24,
1999. Following graduation
from medical school, Dean returned to his home in Phoenix,
AZ, where he interned at Good
Samaritan Hospital. He practiced
general medicine for five years
before taking a three-year residency in psychiatry at Colorado
Psychopathic Hospital (19611964). He then went into the
private practice of psychiatry in
Phoenix , retiring in 1995 from
active practice. He continued as
a consultant until his death. He
is survived by his wife, janet,
and four children: Patricia Lewis,
Robert T. Dean, Ill, j. Richard

Class of 1994 during Spring Clinical Day and Reunion Weekend
First row, left to right: Ted Szarzanowicz, Michelle Penque, Carol Killian,
Patricia Geil, Maya Srivastava, Gloria Delvalle; second row, left to right:
Thomas BurneHe, Wendy Snyder, Richard Kozak, Amy Ferry.
Dean and Misty Ihrke; and five
grandchildren: jesse Lewis, 15 ,
Carly Lewis, 12, Kelsey Ihrke, 8,
and Lindsey and Taylor Ihrke, 2.
His wife, janet, says, "He loved
the practice of medicine and,
especially, psychiatry. It never
became routine or mundane
for him. "

IN MEMORIAM
F A C U L T Y
ELLIOTT MIDDLETON JR ., MD ,

a former professor of medicine
and pediatrics in the School of
Medicine and Biomedical Sciences , died on March 7, 1999,
at Maine Medical Center, in
Portland, ME, after a brief illness. He was 73.During his 19
years at UB , Middleton served
as director of the Division of
Allergy and Immunology in the
Department of Internal Medicine and co nducted research on
the biological effects of natural
food substances on health. He
was a diplomate of the American Board of Allergy and Im-

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munology , which

Muscular Dystrophy Association
of Western ew York at the
former E. ] . Meyer Memorial
Hospital and at WCA Hospital in
jamestown. The Muscular Dystrophy Association presents an
annual medical award in his

he co-

founded , and the American
Board of Internal Medicine.

name. Link conducted research
on cerebral palsy and muscular
dystrophy, including clinical tests
on several drugs for treatment of
the diseases. He was chair of the

Middleton was also a past president of the American Academy
of Allergy and Immunology, and
from 1983 through 1988, he
served as editor of the]oumal of

Western ew York chapters of
the Cerebral Palsy Association
and the Muscular Dystrophy
Association and for several
years was chair of the New York
State Cerebral Palsy Advisory
Board. He was a
member of the
board of
direc t ors
of Special
Help for
Special Children and the
medical advisory committee
for the March

Allergy and Clinical Immunology. In 1991, he received the
Distinguished Service Award
from the American Academy of
Allergy and Immunology.
JOSEPH

s

K . LINK ,

who
served as a
faculty member
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Medicine and
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�BUFFALO PHYSIC IAN

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••rsici••

ASSOCIATE VICE PRESIDE

T FOR

UNIVERSITY SERVICES

Dr. Carole Smith Petro

Dear Alumni and Friends,

DIRECTOR OF PUBLICATIO

Kathryn A. Sawner
EDITOR

As you can see, the magazine has a
new look. With the beginning of the new millennium, its Editorial Board and staff decided
now was a good time to update the publication's eight-year-old design and give it a

Stephanie A. Unger
ART D I RECTOR/DES 1 G N E R

Alan]. Kegler

"cleaner," more contemporary appearance. Most notable are the new cover masthead,
designed to allow more room for the photo image, and the new typefaces inside, chosen

ASSISTANT DESIGNER

Lynda Harmel

for easier readability. Also, the articles themselves are formatted in a more varied way in
order to invigorate content and better convey the stories about our medical community.
As always, your feedback is important and we hope you will e-mail, call, or write us with
your comments.

PRODUCTION CooRDINATOR

Cindy Todd
STATE UNIVERSITY OF

One aspect of Buffalo Physician that hasn't changed is its goal of keeping its readers
apprised of developments affecting our school. As we enter the new
millennium, one topic that will be closely followed is the fact that

EW

YoRK AT BuFFALO ScHOOL
OF MEDICINE AND
BIOMEDICAL SCIENCES

Dr. john Wright, Dean

stewardship of increasingly scarce resources continues to represent our
most significant and pressing challenge, a situation that will no doubt
extend well into the years ahead. Superimposed upon significantly reduced
state financial support (related to negotiated, but as yet unfunded, state
salary increases) and significant reductions in hospital support (GME
and Part A funding), we are headed for some difficult times indeed. In
addition to the effects of managed care and the reduced hospital funding related to the
1997 Balanced Budget Act, we have yet to feel the effects of the pending, much publicized,
GME-funding "reform"- a particularly critical issue for New York State. Those of you
associated with other academic medical centers around the country are no doubt
experiencing similar challenges.
Despite all the gloomy financial projections, however, life does go on. A number of
positive accomplishments over the past year are beginning to have effects. While work on
the new curriculum is still in progress, some physical improvements have already been
accomplished. Refurbishing G26 and Butler, our two major lecture halls, has been
extremely well received and by late spring we hope to have renovated more appropriate
student study space and offices for key student organizations. In addition, planning has
begun for the redesign of Farber 144, our most challenging lecture room rehabilitation
project thus far. When completed, the physical facilities available for medical education
on the South Campus will not only be attractive but more functional and up to date.
Finally, through their own initiatives, our students continue to inspire and motivate

EDITORIAL BOARD

Dr. Bertram Portin, Chair
Dr. Martin Brecher
Dr. Harold Brody
Dr. Linda]. Corder
Dr. Alan]. Drinnan
Dr. ]ames Kanski
Dr. Elizabeth Olmsted
Dr. Stephen Spaulding
Dr. Bradley T. Truax
Ms.]ennifer Wiler
Dr. Franklin Zeplowitz
TEACHING HOSPITALS

Erie County Medical Center
KA.L£/OA HEALTH:

Tire Buffalo General Hospital
The Children's Hospital of Buffalo
Millard Fillmore Gates Hospital
Millard Fillmore Suburban
Hospital
Roswell Park Cancer Institute
Veterans Affairs Western
New York Healthcare System
CATI-IOLIC HEALTH S'iSTE.\1:

Mercy Health System
Sisters of Charity Hospital
Niagara Falls Memorial
Medical Center

us all. Of particular note is their willingness (perhaps a more appropriate term would be
"eagerness") to help one another. In addition to the Students Offering Support (S.O.S.)
Program described in this issue of Buffalo Physician, student-run tutorials have cropped
up at a variety of levels, in particular those involving sophomores helping freshmen.
Although. faculty supervision is provided, it is really the students who drive these
programs.! think you will agree that whatever this new millennium has in store for us, our
graduates will continue to play a major role in shaping the future of medicine.

7

~~ MD

Dean, School of Medicine and Biomedical Sciences

@TIE SUI£ IIIYIISITT IF 1£11 Tlllllllfflll
Buffalo Physician is published
quarterly by the State University of
New York at Buffalo School of
Medicine and Biomedical Sciences
and the Office of Publications. It rs
sent, free of rharge, to alumni,
faculty, students, resitients, and
friends. The staff reserves the right
to edit all copy and submissions
accepted for publicatio11.

S

�VOLUME

34,

NUMBER 0

p

H

y

s

c

A

Features
The 'Insider' Steps Out
Jeffrey Wigand, PhD '73, takes
on the tobacco industry
BY NICOLE

PERADOTTO

Back into Shape
Help for osteoporotic compression fractures of vertebrae
BY

S. A.

UNGER

The Edge of Possibility

Russell Crowe portrays Jeffrey Wigand in a.scene from The Insider. The film dramatizes
the UB graduate'slife-shattering ordeal with the tobacco industry.

Irwin Ginsberg, MD '44,
otologist and inventor
BY

S. A.

UNGER

COVER PHOTO

20 New Roles for
Dr. Carlos Pato
and Dr. Mary
Anne Rokitka

21 Dr. Charles
Severin and
Debra Stamm
join OME

22 Students form
rock band

25 Melatonin
linked to bone
growth

26 Research
Institute on
Addictions
joins UB

27 $4.2 million
NIH grant to
study bipolar
disorder

28 Han a Choe,
Class of 2002,
describes how
new S.O.S.
peer-support
group was
formed in
response to
survey of firstand second-year
students

17 Robert E.

Alumnus

31 Mark your
calendars for
Spring Clinical
Day and
Reunion
Weekend 2000!

3D Thomas
Frawley, MD
'44, recalls
faculty support;
establishes
endowment
for research

BY WILSON

BAKER

35 Saar A.
Porrath, MD
'61, remembered

JAN2 8

LIUuatif

N

���First Whiff of Smoke

copy of the minutes-one that had been cut down, the scientist
says, to "two and a half pages of vanilla."

In 1989, Wigand-who earned his doctorate in biochemistry at the
University at Buffalo School of Medicine and Biomedical Sciences
in 1973-accepted the most lucrative job of his career: a $300,000a-year position as vice president for research and development at
Brown &amp; Williamson, a subsidiary of British-American Tobacco.
Presiding over 243 employees and a $30 million budget, Wigand
was the senior scientist at the world's second-largest tobacco company, manufacturer of Kool, Viceroy and Capri cigarettes.
To his former colleagues, it must have seemed like Wigand was
sleeping with the enemy. After all, he had spent more than two

"Missing were concepts and discussions that were very controversial and contentious-concepts that could prove an embarrassment during litigation. And I had no choice in the matter. I had to
[sign off]."(A Brown &amp; Williamson attorney has denied that
documents were improperly altered.)
Wigand was stunned: A lawyer telling him how to think about
science? "That bothered me immensely," he recalls. But things got
stranger still. According to Wigand, after the Vancouver conference the company held a "Caution in Writing" seminar, offering

decades in health care, working as a director of
corporate development for Pfizer, director of
WIGAND REFERS TO THIS TIME-CHRONICLED IN THE
marketing for Ortho Diagnostics Systems (a
division of}ohnson &amp; Johnson) and senior vice
MOVIE THE iNSIDER-AS fHE PERIOD WHEN "ALL HELL
president of marketing for Technicon, a company that sells blood-analysis equipment.
BROKE LOOSE."H IS MARRIAGE WAS FALLING APART,
Tobacco?
"!thought I was going to be using my skills
HE FEARED FOR HIS LIFE, A• D CBS HAD HIRED FORMER
to make a difference-to make an intrinsically
SECRET SERVICE AGENTS TO ESCORT HIS DAUGHTERS
unsafe product safer for those who had to smoke.
I thought I could do something that would
TO SCHOOL.
make a difference socially," says Wigand, who
also holds a bachelor's degree in chemistry and
a master's degree in biochemistry from UB.
Ten months into his tenure at Brown &amp; Williamson, howparticipants advice on "how to write, what not to write, who gets
ever, Wigand caught his first whiff of smoke. Attending a meetcopies of what, who communicates with whom. A system was
ing in Vancouver, British Columbia, he and other scientists
created by which information was controlled and edited and vetted
from British-American Tobacco's subsidiaries discussed possiby lawyers," he contends.
bilities for safer cigarettes. Following the five-day meeting,
At company parties, Wigand began overhearing colleagues
Wigand returned to Brown &amp; Williamson's Louisville, Kenusing code words: "Zephyr," for example, meant "cancer"; "Ariel"
tucky, headquarters and enthusiastically circulated a 22-page
and "Project 16" referred to smoking research Brown &amp; Williamson
summary of the meeting's minutes to his colleagues. A few days
conducted during the 1970s. "These were documents I couldn't read.
later, a company lawyer asked Wigand to sign off on a revised
I was the senior scientific officer for the second-largest tobacco

!I

I

l uffal• Pb pici11

W1nter

2000

�company in the world, and I couldn't get access to research documents," he says.
By this time, Wigand had grown increasingly unsettled about
his company's practices. It wasn't only the fact that his daughters,
who learned about the dangers of smoking in school, were asking
him, "Why do you do what you do?" He was also starting to grapple
with that question himself. And yet, Wigand stayed. He stayed, he
says, even after he realized that the company was not committed to
a safer cigarette.
He stayed even after repeatedly dashing with the company's thenpresident, Thomas Sandefur. The more questions he asked, the more
isolated he became. Wigand says he felt like everyone was watching
him and describes how his office was moved from a remote section of
the building to an area adjoining the offices of the senior executives.
Then, in March 1993, Wigand was fired. "I was between a rock
and a hard place," he says, explaining why he didn't leave until
forced out. "I had relocated my family, and I guess I just didn'twant
to create havoc for them.
"Don't mistake me," he adds. "I was looking for a job. But
leaving the health-care industry to work in the tobacco industry
and then trying to get back into health care is not a simple task."

Wigand says he was fired after he objected to the use of the
additive coumarin in pipe tobacco. After reading a study showing
that the vanilla-like flavoring causes tumors in mice, he urged
Sandefur to remove it from Brown &amp; Williamson's products. "I felt
that was enough to warrant that we take it out immediately. But I
was told to mind my own business and to keep searching for another
replacement. I took a stand and was fired two months later." (Brown
&amp; Williamson spokesmen have said that the company used safe
levels of coumarin and that it does not use the additive anymore.)
ix months after Wigand was fired, Brown &amp; Williamson
sued him for reportedly violating his confidentiality agreement by discussing his salary and health-care benefits with
a former colleague. The company interrupted his severance and health-care benefits, which he especially needed

for his daughter Rachel, who had been diagnosed with spina bifida.
In order to have the suit dropped, Wigand reluctantly agreed to an
onerous confidentiality agreement-one he would ultimately break.

Couldn't Keep Silent Any Longer
Jeffrey Wigand might have gone down as just another former
tobacco executive- one of hundreds who leave the industry quietlyand take company secrets to the grave. "All I wanted when I left
was what I was entitled to-my severance pay and retirement
benefits," Wigand says. But when company executives decided to
sue him, "it came back to haunt them," he adds.

Winter

2000

l 1flal• Hysicin

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�In early 1994, Wigand agreed to help Lowell Bergman, a
producer for 60 Minutes, analyze documents from Philip
Morris about that company's research into fire-safe cigarettes.
"They code-named it 'Project Hamlet: To Burn or otto Burn,"'
Wigand remembers.

As it turns out, Wigand wasn't the only one worried about
lawsuits. CBS executives feared that Brown &amp; Williamson would
charge them with "tortious interference," claiming that they had
induced Wigand to break his confidentiality pact. In an unprecedented and embarrassing move by the network, CBS shelved the
interview in the fall of 1995.

she poured through the documents, his anger mounted.
"The industry has always said [a fire-safe cigarette] was a
technical impossibility. And then I read in those papersproduced by Philip Morris in 1985 and 1986-that they
had developed a fire-safe cigarette and had tested it against
their leading product, Marlboro, and had found it equal
to Marlboro. But they elected not to put it into the marketplace because there was no legislation that forced them
to." (A Philip Morris spokesman has said in previous
published reports that the company has been unsuccessful
in creating a fire-safe cigarette, but that research on

Wigand refers to this time-chronicled in the movie The
Insider-as the period when "all hell broke loose." His marriage
was falling apart, he feared for his life. CBS had hired former
Secret Service agents to escort his daughters to school. He kept a
gun in his house. When he traveled, he used assumed names and
unmarked entrances.

I

it continues.)
Bergman quickly came to realize that Wigand had more to offer
than his work as a paid scientific consultant. He had a story to
tell-one that no one had told before. Unaware that Wigand had
signed a confidentiality agreement, Bergman began pushing him to
go public.
Meanwhile, Wigand's name began making the rounds
within the antitobacco crowd. He became an
advisor to the Food and Drug Administrationusing the code name "Research"-and served as a
witness in several federal inquiries into the

Out There. Naked.
After the 60 Minutes debacle, Wigand's name was leaked to the
press, along with lengthy excerpts from his interview with Mike
Wallace. Four days after the story broke, Brown &amp; Williamson sued
Wigand, with the company's lawyers instructing him to appear in
a Kentucky court for violating his confidentiality agreement.
Defying the Kentucky order, Wigand traveled to Mississippi.
Facing possible contempt proceedings, he went ahead and testified
in that state's massive lawsuit against tobacco companies to recoup
Medicaid money paid out for smoking-related illnesses.
"I didn't go to jail," Wigand says. "But the threat was very real."

«HAD IT NOT BEEN FOR JEFF WIGAND AND

tobacco industry.
INDIVIDUALS LIKE HIM COMING FORWARD A. D
Then, on April 14, 1994, the CEOs of seven
BASICALLY DRAWING ATTENTION TO THE TOBACCO
tobacco companies sat before the House SubcomINDUSTRY, WE WOULDN ' T HAVE HAD THE TOBACCO
mittee on Health and the Environment and testified under oath that they did not believe nicotine
SETTLEMENT."
-K. MICHAEL CUMMINGS, MD
was addictive. As Wigand watched his ex-boss,
Sandefur, raise his right hand, something in him
snapped. "That's when I knew that if I kept silent
any longer I would be just as culpable asanyofthe men on TV. !just
After Wigand testified in Mississippi, a reporter with the Wall
couldn't live with my conscience anymore. Somebody had to do
Street journal obtained the sealed deposition and reproduced excerpts
it," he says.
from Wigand's allegations of company misdeeds. (It was
Within weeks, a man called his house twice, warning Wigand to
keep an eye on his daughters.

Confidentiality Disagreement
In August of 1995, Wigand agreed to a 60 Minutes interview. Yes,
he would discuss what he knew of Brown &amp; Williamson's use of
coumarin. Yes, he would discuss how the documents about safer
cigarettes had been cut. Yes, he would say that he believed Sandefur
perjured himself when he said he believed nicotine wasn't addictive-but only if CBS promised to cover his legal costs in the likely
event that Brown &amp; Williamson sued him.

6

lulfalt Pbysiciu

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2000

only then that CBS aired the interview- a bowdlerized version on

the network's evening news and the complete version on 60 Minutes.)
Less than a week later, the Wall Street journal reported on
another story related to Wigand-a 500-page dossier prepared by
his former employer titled "The Misconduct of JeffreyS. Wigand
Available in the Public Record." In an attempt to discredit him,
investigators working for Brown &amp; Williamson combed through
Wigand's past. They read his PhD dissertation for possible
plagiarism and searched his resume for misstatements. They even
looked into his demands that an airline reimburse him for a
cleaning bill after his luggage was returned wet.

�is "an American hero."
"There have been many people who got
out of the industry and have insider information, but very few who have spoken out.
He spoke out against the industry, causing
great disruption in his life," says Cummings,
adding that Wigand is today serving as a
consultant on a Roswell Park project to
determine a protocol for testing nicotine

During production of The Insider, Jeffrey Wigand, left, meets his film counterpart Russell Crowe (second from the
left) and lowell Bergman (rigbt) meets AI Pacino (second from the rigbt), who portrays him in the film.

delivery devices.
"Had it not been for Jeff Wigand
and individuals like him coming forward
and basically drawing attention to the
tobacco industry, we wouldn't have had
the tobacco settlement," Cummings
points out.

"

...
..
..

.
.•
®

..
.
.

...

....•

In its article on the contents of the dossier, the
Wall Street Journal concluded: "A close look at this
file, and independent research by this paper into
WIGAJ. D WAS STUNNED: A LAWYER TELLING HIM HOW
key claims, indicate that many of the serious
TO THINK ABOUT science? ((THAT BOTHERED ME
allegations against Mr. Wigand are backed by
scant or contradictory evidence .... Some of the
IMMENSELY." BUT THINGS GOT STRA. •GER STILL.
charges ... are demonstrably untrue."
I had people inspecting every aspect of my
life," Wigand recalls. "And they took it all out of
"Jeff Wigand showed just what price you are going to pay if
context. Because I went after somebody because my luggage was
defect," adds Joe Cherner, president of Smoke-Free
you
ruined in transit doesn't mean I falsified a claim. In the end, I must
Educational
Services.
say that it backfired on them. But that was a hard place to be. Out
Wigand doesn't want to discuss the most severe price he paid by
there. aked .
speaking out-his marriage, which collapsed under the pressure
"It was a terrifying time in my life. This wasn't for the faintof that period. And yet, if he had to do it over again, he says he
hearted. Many people would not have given me good odds of
wouldn't hesitate.
surviving, much less succeeding."
"I have no regrets about what I did. I would do it again ifl had
to.
Hopefully,
history will reflect what I did as something that was
No Regrets
honorable-something others will take as a lesson.
' ' I n June of 1997 the proposed multibillion-dollar settlement
"I take no small satisfaction in the role I played-no small
of the Medicaid suit that originated in Mississippi was held
satisfaction," he adds. "I continue to spread the word. And I will
up by one sticking point: Brown &amp; Williamson's lawsuit
not stop spreading the word."
4D
against Jeffrey Wigand. After a series of closed-door meetings, company executives finally agreed to drop the suit,
allowing the settlement to proceed and Wigand to
get on with his life .
Today he's a high school teacher in Charleston,
South Carolina, and the head of Smoke-Free Kids,
an organization he founded that educates children
about the perils of smoking. "I use actual industry
documents and experiments and examples from the
silver screen and advertising to help them make
healthy and educated choices," he explains.
To K. Michael Cummings, MD, director of cancer
prevention at Roswell Park Cancer Institute, Wigand

Winter

2000

I I

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��I
New treatment for osteoporotic compression fractures of the venebra
BY

PHOTO

BY

JosH

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Winter

2000

ltffal1 Pbrsicial

9

�lee Guterman, PhD, MD

THE PAST, when an osteoporotic compression fracture occurred, there wasn't much
physicians could do for their patients. More often than not, standard treatment included pain
&lt; T

medication, bracing and bed rest.
Today, however, the outlook for treatment of these fractures is considerably brighter due
to the introduction of a new procedure called percutaneous vertebroplasty, the goal of which
is to strengthen injured vertebral bodies by filling them with a type of bone cement
traditionally used by orthopedic surgeons to affix prosthetic implants. Currently, this
investigational procedure is being performed by only a small number of physicians in the
United States, one of whom is Lee Guterman, PhD, MD '89, assistant professor of neurosurgery at the University at Buffalo's School of Medicine and Biomedical Sciences.
According to Guterman, percutaneous vertebroplasty was
developed by a group of physicians in France in the mid-1980s and
popularized in the United States in the mid-1990s by colleagues of
his at the University ofVirginia in Charlottesville-Jacques Dion,
MD, and Mary Lee Jensen, MD-both of whom are radiologists.
In the past year, Guterman, who practices at Kaleida Health's
Millard Fillmore Gates Hospital, has completed more than 20
percutaneous vertebroplasties. Dedicated to teaching the procedure to other specialists around the country, in May 1999 he
taught a course at the American Association of eurological
Surgeons in New Orleans, and in October he traveled to Boston,
where he taught a course at the Congress of Neurological
Surgeons. Recently, he served as a member of a committee that
developed standards of practice guidelines for percutaneous
vertebroplasty. *

Needle Placement with fluoroscopic Guidance
Patients undergoing percutaneous vertebroplasty receive local
sedation and are awake throughout the procedure. A needle
similar to that used for bone marrow biopsies is used to penetrate
the injured vertebra. Precise placement of the needle is accomplished using fluoroscopy, a form of real-time X-ray that enables
the surgeon to visualize the needle tip and follow its progression
in three dimensions.
The cement-called methyl methacrylate-is injected via the
syringe into the fractured vertebra and must be mixed with
carefully timed precision because it begins to harden in minutes.
Before the cement is prepared, however, surgeons first must
perform vertebral venography, which accomplishes several things:
It helps confirm needle placement within the bony trabeculae,

10

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2000

clarifies definition of the fractures in the bony cortex and, most
importantly, according to Guterman, outlines the venous drainage pattern.
"The vertebral body is made up not only of bone, but it's also
made up of veins that drain into the vena cava," he says. "So the
first thing we do is inject a contrast medium to see what the venous
drainage pattern is. If it is very fast-flowing, there's a chance the
cement will enter the vena cava and be carried up to the heart and
into the lungs."
According to Guterman, if a fistula, or direct connection, is
found between the vertebral body and vena cava, the surgeon
has several options. "To shut off that connection," he says, "you
can take cement that is at a stage where it is ready to solidify and
inject it more slowly, which closes off the pathway. Then you
can approach from
the opposite side and
fill up the vertebral
body from there. I
also sometimes use
small sponges made
of collagen foam to
seal the passageway,
then go ahead and
insert the cement."
Once the venograph has confirmed
placement of the Left is an X-ray of a vertebra prior to percutaneous
needle and a safe vertebroplasy, and right is an image of the same
venous drainage pat- vertebra filled with the methyl methacrylate
material. Once the procedure is completed.
tern, the surgeons mix patients can ambulate after two hours bed rest.

�Vertebral bodies are strengthened by filling them with a quick·setting bone cement.
the ingredients of the cement until a "toothpaste"
or "cake glaze" consistency is reached, at which
time it's ready for insertion. Because the material
is not sufficiently radiopaque, chemical compounds
containing either barium or tungsten powder are
added to it at this time. "By doing this, we opacify
the cement, which means it will scatter X-rays, so when we inject the
material we can view it much like you would view an angiogram,"
Guterman says.
In general, complications for percutaneous vertebroplasty are
rare. One important reason why surgeons need to view the cement
as closely as they do, however, is to avoid the procedure's most
serious potential complication-epidural overflow with spinal
cord compression.
ormally, the procedure takes approximately one hour, depending on how many vertebrae are treated. Guterman says he routinely
treats two levels per session, and sometimes up to three. Once the
vertebroplasty is completed, the patients rest in bed for a minimum
of two hours in order to assure that the cement sets properly. After
that, they are free to ambulate and resume normal activities.

Vertebroplasty'sFuture: AWork in Progress
uterman reports that 70-80 percent of the patients he has
treated with vertebroplasty have experienced improvement in
symptoms; he also notes that Drs. Jensen and Dion at the
University of Virginia recently completed a study on 100
patients in which they demonstrated a decrease in pain, a decrease
in patients' use of narcotics and improved ambulation. The procedure is currently not approved by the Food and Drug Administration; however, clinical trials are planned, and Guterman anticipates participating in a controlled study at UB in the near future.
While percutaneous vertebroplasty has proven to be effective for a growing number of patients, Guterman emphasizes
that the procedure is not for everyone and that proper screening of patients is essential to success. "People have back pain
for a lot of reasons, and often they have multiple complaints,
especially if they are older," he says. "They could have osteoporotic compression fractures, but they could also have
degenerative disease or a herniated disc. However, if they can
identify one spot in particular that is painful and you take an
X-ray and find there's a fracture, then there's a reasonable
certainty- maybe 80 percent- that vertebroplasty is going to
work. It's not going to cure them of osteoporosis and it's
probably not going to take away all their pain, but it will very
likely take care of the pain that's due to that fracture. "

In looking to the
future, Guterman
predicts a day when
percutaneous
vertebroplasty will
be used preventively,
with significant savings in health-care costs. "I can see the dayand this is conjecture on my part-where imaging technology will
be used to identify high-risk patients who are then treated prophylactically with the type of bone cements we are using today or yetto-be developed materials that either regenerate bone or bolster it
so fractures don't occur in the first place," he says. "The savings in
the area of rehabilitation alone would be huge because patients
with multiple osteoporotic compression fractures usually never
recover full function. "
In addition to osteoporotic compression fractures, percutaneous vertebroplasty is also being used for malignant tumors of the
bony portion of the spine, according to Guterman. "This does not
cure the tumor, of course, but if a patient is experiencing significant pain and can't ambulate because of structural problems,
vertebroplasty is one method for dealing with this limitation."
Guterman has already seen notable improvements made to the
way vertebroplasty is performed and reports that "a company
called Parallax Medical has devised a new method for delivering
the cement, which is extremely helpful; it changes the whole
procedure and, in my opinion, makes it much easier."
Teaching other neurosurgeons about vertebroplasty is a priority
for Guterman. " eurosurgeons are very well suited for vertebroplasty because they typically operate on the spine and are able to
understand radiographic anatomy of the spine," he says. "Also,
they have to use the same trajectory to put the needle in that they
would use to introduce a pedicle screw for spine fusion, so it's just
another step to instruct them in how to properly insert the cement."
While few physicians in the United States are currently trained
to perform percutaneous vertebroplasty, Guterman anticipates
that this will change as ongoing studies confirm its benefit to
patients suffering from osteoporotic compression fracture or
malignant spinal tumors. "We're finding this to be a very effective
procedure," he concludes. "It works."
CD
*The standards ofpractice guidelines were developed under the auspices
of the American Society of Neuroradiology, the American Society of
Interventional and Therapeutic Neuroradiology, and the American
Society of Spine Radiology. The committee on which Dr. Guterman
served was co-chaired by john D. Barr, MD, and fohn M. Mathis, MD.

W i11 t e r

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By
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L'

�Working at the

Despite the fact that his field has developed at such a brisk
pace over the course ofhis career, Ginsberg was not a man to be
left behind. By the time he retired from active practice in 1997,
he was widely regarded as one of Buffalo's finest ear surgeons.
A hugely extroverted man with a flair for energetic joke telling,
Ginsberg is also known for his warm bedside manner, his
generous mentoring of students, his quick mastery of basic
science and his downright uncanny ability to understand and
engineer biomedical devices and instruments. Given that he is
now planning to bring to market a state-of-the-art device he
invented for the removal ofear wax, the question perhaps is not
whether Irwin Ginsberg has kept up with technology, but
whether technology has kept up with Irwin.
leci~ilf

u lee••• a lutu

It was through Ginsberg's love of the automobile that his talent
for science and engineering first became evident. Some of his
earliest memories are of refusing to go to sleep at night until

Otologist Irwin Ginsberg,
MD '44-surgeon, educator,
researcher and inventor-reflects

his mother let him play with a
set of toy cars with which he
was infatuated. As an adult,
this interest translated into a

fascination with owning and renovating vintage automobiles,
and by mid-career he was full tilt into amassing what was to
become one of the best classic-car collections in the world.
But it wasn't Ginsberg's innate technical abilities that drew
him to medicine and surgery; it was the near death of his
mother when he was six years old. "She had a ruptured appendix, was riddled with peritonitis and was admitted to Buffalo
General Hospital under the care of Dr. Marshall Clinton," the
78-year-old Ginsberg recalls. ''I'll never forget it. I can still see
the room: It was on Michael Corridor on the third floor. Every
time I walked down that corridor when I was an intern and a
doctor, I remembered the time my mother was a patient in
that room."
Ginsberg especially remembers going to the hospital one
day with his father and overhearing Dr. Clinton say, ''I've done
all I can do. All I can tell you is to go home and pray. It doesn't
look very good."
"I heard that and if affected me deeply," Ginsberg says. "As
it turned out, she was on death's door for three weeks and then
suddenly went through some sort of crisis and recovered. I
remember the day Dr. Clinton put his arm around my dad's
shoulder and told him we could take her home in a few days. I
knew right then and there that's what I wanted to be-a doctor.

on fifty years of change.
II r

11

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er 2 0 0 0

1111a11 nrsicin

�I just figured you had to be something really great if you could do
that for somebody; if you could help a boy get his mom back."

T a·ning at Home and Abroad
Upon graduation from Bennett High School in 1938, Ginsberg
entered premedical studies at the then-University of Buffalo. By
1941 he had earned a degree in chemistry and was admitted to the
university's School of Medicine. "We finished in three years at
that time because doctors were wanted for the war, so they put
us all through an accelerated program, which meant we went to
school during the summer, too," Ginsberg says.
"I was only 22 when I received my medical
degree, and I had gotten married just a year
earlier," he adds, explaining that this was a
time of great change in his life.
Following his graduation in 1944, Ginsberg
completed his internship at Buffalo General
Hospital, after which he served in the navy for
several years. Upon discharge from the service,
he moved to ew York City to pursue studies in
surgical pathology and research at Columbia Presbyterian Medical Center. He completed his residency in surgery at Mount Sinai
Hospital in 1948 and the following year returned to Columbia
Presbyterian Medical Center to begin a residency in otolaryngology, training under Edmund Fowler, MD, whom he considers to
be one of his foremost mentors.
Asked why he chose to specialize in otolaryngology, Ginsberg
explains, "When I was rotating through the head and neck department during my general surgery training, I fell in love with the ear,
just pure and simple, because of the beauty of it. And I'm still in
love with it; it's never tired me out because when you work with
the ear, you're often working at the edge of possibility and so that
has been a great challenge for me."
Ginsberg's appreciation for "working at the edge of possibility" and his aptitude for engineering merged in a fortuitous way
while he was completing his residency in otolaryngology and was
strapped for funds. During this time, he became aware of a
research project at the medical center in which investigators were

l alfal1 Plysici11

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2000

measuring the electrical potentials for the stomach in an effort to
develop a method for early detection of stomach cancer. In order
to do this, they needed to place a silver-silver chloride electrode
in one lumen of a Miller-Abbott tube, a task that was proving
difficult because the electrode had to be housed in a tiny piece of
Lucite machined out of a Lucite rod.
"They couldn't get anybody to make those pieces because they
were so small, and they drove people mad," Ginsberg recalls with
a chuckle. "So I said I could make them. I went down to Canal
Street and bought a wrecked jeweler's lathe for eight dollars, put
new bearings in it, got a pair of Zeiss twopowered magnifying glasses and developed a
technique for making the electrodes," he says.
"They worked pretty well, and they helped me
get through my residency and support my wife
and two children."
When Ginsberg completed his training in
otolaryngology, his professors declared him
"a good technician" and recommended that he
go to Europe for further training. "In those days,
they'd say they were sending you to Europe to 'get polished,"'
Ginsberg recalls. He spent 18 months abroad and completed a
fellowship at Guys Hospital in London, where he trained with
Robert J. Cann and Sir Victor egus, as well as with other surgeons
of repute in Switzerland, Sweden, Scotland and Denmark.

The Golden Da so

C OS
ge
Once his training was completed, Ginsberg decided to return to
Buffalo, despite having offers to join practices in London and New
York City. "I like Buffalo as a city, and my family was here, so I
decided to return here to live," he says. "I opened up an office at
333 Linwood, a building that had many E T men in it at the time,
and I did very well." So well, in fact, that in 1968 he built his own
office building at 897 Delaware Avenue, which today remains one
of four locations for the Buffalo Otolaryngology Group.
It was during those first years when Ginsberg was in private
practice-in the early 1950s-that stapedectomy came to be
standard surgical procedure for the treatment of otosclerosis, a

�IN ]UNE

198J,

DAVID RADLIN, AGE 10, TOOK A RIDE WITH DR. lRWL GINSBERG IN HIS

VI 'TAGE PACKARD. DAVID's FATHER, BARRY RADLI ',REMEMBERS THIS RIDE WITH
FO 'D. ESS BECAUSE, WHILE E.' ROL'TE, DAVID HAD A TALK WITH DR.

GI. 'SBERG

A 'D

DECIDED HE WOULD WEAR HIS HEARING AIDS AT SCHOOL, DFSPITE THE I-ACT THAT HE WAS
BEl TG TEASED BY HIS CLASSMATES. I

T

1996

DAVID GRADUATED FROM SYRACUSE

UNIVI:.RSITY WITH A DEGREE L' RETAIL AND MANAGE 1E T AND HASSI. TCE
EMBARKED ON A CAREFR IN VISUAL DISPLAY.

hereditary ear disorder that causes deafness due to growth of excess
bone in the middle ear. Ironically, stapedectomy was the first
medical procedure in which microsurgery was utilized, and in
mastering this technique, Ginsberg couldn't help but recall his early
work making electrodes with the aid of Zeiss magnifying glasses.
"The golden days for microsurgery were when stapedectomy
was perfected," he recalls, "but the most dramatic thing for a
surgeon was realizing you could help someone who was deafhear.
The operation was done under sedation, so while the patients were
still on the operating table, they'd say, 'Oh, it's wonderful, doctor.
I can hear!' I tell you, that was a great feeling."
ot so great, however, are his memories of the patients no
surgical intervention could help. "When a mother would bring
her new baby to me and say, 'I wonder if my child can hear or not,'
and I knew very quickly he couldn't, sometimes I'd have to walk
out of the office to compose myself before I could talk with the

mother and tell her her baby was deaf, with all that such a diagnosis
entails. It's an awful sentence to give someone."
Ginsberg says that children who are deaf or hard of hearing are
in special need of support and encouragement. He recalls fondly
a case of a 10-year-old boy, David Radlin, who resolutely refused
to wear his hearing aids because he was teased mercilessly at
school. In desperation, his father, Barry, brought him to see
Ginsberg. "I took him for a ride in my Packard with the top down,
and afterward he decided he'd wear the hearing aids," Ginsberg
remembers with a laugh, adding, "You have to support them all,
support them like mad!"

P onee

ng Coc

ea

Imp an s

In 1968 Ginsberg hired Thomas P. White, MA, MBA, as his
audiologist, and the two have worked together ever since. White,
who holds a joint appointment as an assistant professor in the

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Department of Communicative Disorders and Sciences at the
University at Buffalo, worked with Ginsberg in the early 1980s to
develop the first comprehensive cochlear implant program in
Buffalo. "Our group always prided itself on being up on state-ofthe-art developments, so we had kept our eye on the implants for
a number of years as the procedure was going through its early
stages of experimentation," he says.
In 1984, Ginsberg decided it was time to move ahead with
learning the procedure himself, so he took White to Europe,
where they traveled to England, Germany, Switzerland and
Austria to talk to and observe surgeons performing the implantations. In Vienna they met with electrical engineers Erwin and
Ingeborg Hochmaier, who had designed a cochlear implant called
the Vienna Device. "Dr. Ginsberg liked this device best because it
had a special application in that the electrode that did the stimulation didn't enter the inner ear," White explains. "And
he felt this was an important difference
because the inner ear is a very delicate
structure, very small, and he didn't want
to ram a wire in there. Too, he didn't
want to rule out the possibility of
future developments."
Upon returning to Buffalo, Ginsberg
was anxious to begin performing cochlear
implantations, but the Vienna Device,
which was being manufactured in the
U.S. by the 3M Corporation, was still in
the process of being tested by the Food
and Drug Administration (FDA) and was
only available through 10 clinical trial
sites, all of which had already been set up.
Through persistent efforts and a little good luck, Ginsberg's
practice was eventually named a test site when one of the original
investigators dropped out of the trial. In 1985, therefore, he began
performing the procedure according to the strict FDA guidelines.
"We did about 10 patients at the start, and it was a very
emotional experience for all of us," White says. "You wait about
a month for healing to take place, and then you stimulate the
device with the external equipment. When a person tells you that
he's hearing something for the first time in his life, it evokes very
strong feelings. And often the patients cry."

g Researc ing

n en

g

White says Ginsberg contributed greatly to the education of
audiologists in Buffalo by teaching at UB and opening his practice
to students. "When I was hired, Dr. Ginsberg agreed to make his
office accessible to audiology students from the university. Anybody who wanted to could come down to his office and, under
supervision, get experience testing in a real environment. And I

16

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POSSIBILITY

think his professional commitment to the emerging field of
audiology has been exceptional. It has really made a difference for
the students."
In addition, Ginsberg volunteered his time to teach a seminar
at UB called Clinical Otology for the Audiologist. "Throughout
his career, he always treated audiologists as colleagues," says
White. "And he always supported our field because he felt
audiologists helped him to find better ways to treat patients."
In the late 1980s, Ginsberg founded an Ear Research Laboratory to study temporal bone anatomy. Although the laboratory is
no longer in existence, scientists at UB today acknowledge that
Ginsberg's laboratory was in many ways a precursor to presentday laboratories at the university that focus on basic science
inquiries into hearing and deafness.
One such scientist is Richard Salvi,
PhD, professor of communicative disorders and sciences in the College of Arts
and Sciences, clinical professor of otolaryngology and neurology in the School
of Medicine and Biomedical Sciences
and co-director of UB's Center for
Hearing and Deafness. "Dr. Ginsberg
has been one of Buffalo's best ear surgeons for many years, and he's made
significant contributions to the field of
otology in this city. Recently I invited
him to come and give a lecture to my
students, and he brought along with him
a device called the Earigator that he has
invented to remove ear wax," says Salvi,
who agreed to let Ginsberg demonstrate
it on him before the class. "The device is
incredibly well designed; he's worked all sorts of clever features
into it that are really remarkable, and it works very well."
Ginsberg is pleased with his new device, too, and says that it's
in the process of being commercialized. But the Earigator is just
one of many ongoing projects for this protean ear surgeon, who
insists he's only "semi-retired."
Recently, he passed an important personal milestone in his life
when he auctioned off his beloved classic-car collection. "It was
sort of a heartbreak to sell, but what do you do with things like
that in my stage oflife?" he asks. "I drove in a Mille Miglia [a 1,000mile race along the coast of California] about six years ago, but
that was stretching it. I was in my 70s, and I decided I didn't
want to spin out anymore."
Ginsberg may not be spinning out in auto races anymore, but
he's also not sitting back in the slow lane, watching the world go
by. As Salvi observes, "Dr. Ginsberg's at an age when most people
would be lying on the beach, relaxing, but he's sharper than ever,
and he's still contributing to his field."
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�MEDICAL

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1999 Distinguished Medical Alumnus Named
Nationally Recognized Allergist and Immunologist

RoBERT

E.

REISMAN,

MD '56

clinical pro- and aside from his exceptional professional
fessor of medicine and pediatrics, received expertise-for which he is sought after by
the Distinguished Medical Alumnus Award physicians and patients all over the Westfrom the University at Buffalo School of ern ewYork area-he is one of the genMedicine and Biomedical Sciences at a din- tlest, kindest and most thoughtful doctors
ner held in his honor on September 23, I have ever encountered. He is one of a
1999, at the Buffalo Club.
small cadre of physicians who always
A 1956 graduate of the medical school, listens to his patients'
Reisman is an attending physician and complaints."
allergist at Kaleida Health's Buffalo
Although Reisman
General Hospital (BGH) and Children's has been a full-time
Hospital. In addition, he served as co- practitioner throughdirector of the Allergy Research Labora- out his career, he has
tory at BGH, in the Department of also managed to
Medicine at UB from 1970 to 1990.
conduct a superb
Over the past four decades, Reisman research program in
has integrated into his career the varied allergic diseases,
pursuits of clinical medicine, research, according to Kasteaching and dedication to the allergy- sirer. "With Dr. Carl
immunology discipline. He has authored Arbesman, he eluciover 200 articles, papers and book chap- dated many fundaters, many of which address clinically mental aspects of allergic diseases,
relevant issues in anaphylaxis, asthma, especially the mechanisms of insect
drug allergy and stinging insect allergy. He allergies," he explains.
is co-editor of the allergy-immunology text
Reisman's service to his field includes
Expert Guide to Allergy and Immunology, the presidency of the American Academy
which was published in 1999 by the of Allergy, Asthma and Immunology;
American College of Physicians. In addi- chair of the American Board of Allergy
tion, he has played a major role in the and Immunology; a member of the Ameritraining of allergy-immunology specialists, can Board oflnternal Medicine; and chair
as well as students, residents and other of the Residency Review Committee of the
practicing physicians.
American Medical Association for Allergy
Jerome P. Kassirer, MD '57, former and Immunology. In 1993, he received the
editor-in-chiefofthe New England journal prestigious honor of being awarded the
of Medicine, nominated Reisman for the Mastership in the American College of
award. "Dr. Reisman was a year ahead of Physicians, one of only 15-20 such awards
me in medical school in Buffalo and was bestowed by the college each year. CD
my resident at Buffalo General Hospital _ s . A . u N 0 E R
when I was an intern there nearly four
decades ago," he says. "''ve followed his
career closely since that time, and he is one
of the most impressive physicians I have
known. He has become one of the most
highly respected practitioners in Buffalo,

Wint e r

2 000

Lett to right: Jerome
Kassirer, MD. Rena
Reisman. and Hoben
Hersman, MD

l affale Hysiciu

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�MEDICAL

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he Primary Care Summer bternship Program
wishes
to extend a heartfelt thank you to all the preceptors who
continue to make this program a success. Many of these physicians volunteer their time year after year to ensure that students
experience the true practice of medicine early in their careers.
The program, which has just concluded its seventh year,
offers first- and second-year medical students a paid six-week
externship during the summer months. Students are placed in
the offices of generalist physicians throughout Western New
York, where they enjoy varying degrees of interaction with
patients, incl uding taking histories and performing physicals,
while participating in the daily operation of an office.

Jennifer Paglino Adamson Richard Ruh. MD
Mark Swetz, MD
Steve Lana, MD
Antoinette Alonzo
Thomas R. Gerbasi, MD
Victoria Amodeo
Angela Ferguson, MD
Amy Braun
Chester Fox. MD
Audrey Chan
G. Jay lishop, MD
Kristin Clark
Andrea Manyon. MD
Ellen Rich, MD
Jennifer Clementi
Anthony 0.
Jesse Cone
Bartholomew, MD
Jeffrey Conklin
Thomas S. Scanlon. MD
John Brewer, MD
Neu Daley
J. Thomas Reagan, MD
Cheri Dwyer
Keely Dwyer
Dawid Holmes, MD
Kimberly Erway
Colleen Mattimore. MD
Mary Schamann. MD
George Figueroa
John Thompson. MD
James Galas
Gaurang Sheth, MD
Anjeli Gupta
Nicholas Aquino. MD
Aaron Guyer
Brad Truax. MD
Mark Haggerty
Ann Marie Hedges
Gregory Jobes
Michael Kader
Steven Kam
Brian Kenjarski

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Family Medicine
Pediatrics
Pediatrics
Family Medicine
Internal Medicine
Family Medicine
Internal Medicine
Internal Medicine
Internal Medicine
Family Medicine
Family Medicine
Family Medicine
Pediatrics

Family Medicine
Pediatrics
Medicine /Pediatrics
Independent Health
Administration
Independent Health
Brad Truax. MD
Administration
Jane M. Parmington. MD Pediatrics
Internal Medicine
Dnid Milling, MD
Internal Medicine
Jack P. Freer, MD
Independent Health
Brad Truax, MD
Administration
Independent Health
lrad Truax. MD
Administration

Wi11t e r

2 000

The externship program is currently supported by anumber ofsources, including the Charles E. Culpeper Foundation,
the Independent Health Foundation, the Lake Plains Community Care etwork, and the New York State Department
of Health. There is also an opportunity for individuals to
support the program; for example, a special endowment fund
has been established by Evan Calkins, MD, to develop a more
consistent funding source in this age of decreasing capital.
For more information about the Primary Care Summer
Externship Program or giving opportunities, please contact
Susan Orrange at (716) 829-2917/2012 or e-mail her at
sorrange@buffalo.edu.
c:D

Duid Kim

Ellis Gomez. MD
John Sauret, MD
Danielle LaPrairie
Ashok Naik, MD
John Jaeger. MD
Eileen Lau
Chelikani Y.P. Varma, MD
G. Lawrence McNally, MD
Sabina Lim
Frank C. Menadri, MD
Leah Millstein
Dwight Lewis. MD
Morcos Morcos
Howard Sperry, MD
Dhruti Naik
Michael Ndegwa Njuguna Richard Castaldo, MD
lrenda Perez
lrad Truax. MD
Sara Ponkow
Rebecca Puchalski

Karena Steiding
Andrew Swan
Juliane Thurlow
Steven Weitzman

larbara Stouter, MD
Catherine O'Neil, MD
Janet Sundquist, MD
Theodore Putnam. MD
Peter Kowalski. MD
Harry Metcalf, MD
Donald Robinson. MD
Charles Hershey, MD
Frederick Downs. MD
Ashok Naik, MD
John Jaeger. MD
Peter Winkelstein. MD
Sanford Levy, MD
Mark R. Klocke, MD
Michael J. Aronica. MD

Debra Wojtanik
Robert Wong
Adam Wychowski
Dana Yip

Jack F. Coyne, MD
Raphael Wang, MD
Gregory Snyder. MD
John Fudyma. MD

Robert Ramsdell
Laura lendano
Teresa Russell
Dnindra Seelagan
Robert Setlik
Jonathan Siuta
Kristen Smini

Family Medicine
01/GYN
Pediatrics
Pediatrics
Medicine/Pediatrics
Family Medicine
Internal Medicine
Internal Medicine
Independent Health
Administration
Pediatrics
Internal Medicine
Pediatrics
Family Medicine
Family Medicine
Family Medicine
Internal Medicine
Family Medicine
01/CYN
Pediatrics
Internal Medicine
Pediatrics
Medicine/
Pediatrics
Pediatrics
Pediatrics
Family Medicine
Internal Medicine

�Through the (yes of aStudent

I

I

I

Neva Daley , Class of 2001

Preceptor: John Brewer, MD, Upper West Side Family Health Center

Public Heahh
\
externship at the
Upper WestSide Family Health Center with much anticipation. I was unsure what to expect, but I knew I would enjoy
the diversity that family medicine has to offer. As the
externship progressed, I began to realize that the benefit of
being an extern in this particular clinic went far beyond
practicing clinical skills. Yes, I was receiving fine clinical
teaching from the various physicians and nurse practitioners, and I was also getting an introduction to the
complexities of practicing medicine in an underserved community. The patients were primarily African American
and Hispanic of low socioeconomic status. I learned the
importance of having just as much respect for patients in
poor economic situations as I would for those from a
suburban middle class environment. I observed how the
physicians addressed the components of the lives of each
of their patients with thoroughness and sensitivity.
Issues prevalent in this underserved population included
affordability of medication or physical therapy if not
covered by insurance, transportation costs to a referred
physician, lack of compliance for follow-up visits, abuse of
(even the sale of) pain medications, poor family planning
and contraceptive use, and domestic violence.
A significant proportion of the patients also were
refugees from Eastern Europe, the Middle East, Vietnam,
and Africa. Due to the large number of refugees treated at
the clinic, I had to use an AT&amp;T Translator Service with
several patients. During the course of the summer, I was
able to help deliver care to three members of a family who
were among the first wave of refugees from Kosovo. One
had been severely beaten by Serbian soldiers before his
arrival to the United States. I was humbled to be able to
help those who had endured such hardships and brutality.
Each of the refugees I saw this summer expressed so much
gratitude for the care they were given, and I felt deep
satisfaction. It amazed me that I had reached a stage in my
medical education where I could help the poor in this
manner and have a true impact on the lives of others. !twas
as if my childhood dreams of maybe one day serving in an
international capacity were slowly unfolding- right
here in Buffalo.
CD

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Mary Rosenblum Somit Scholar hip
a
he
Assisting undergraduates in the School of Medicine
and Biomedical Sciences
UNIVERSITY AT BUFFALO SENIOR Diana Pratt, who volunteered this
summer to help deliver needed medical services to villagers in remote
areas of the Himalayas, is the first recipient of a Mary Rosenblum
Somit Scholarship. The award, made possible by an endowment
established by former UB executive vice president Albert Somit, provides Pratt with a $1,800 scholarship for the 1999-2000 academic year.
Somit, who served as the university's acting president in 1977,
says he established the endowment "to honor my mother, who like
so many others of her generation, left family,
friends and all that was familiar in Russia to
seek a better life for themselves and their children." Widowed when Somit was four, Mary
Rosenblum Somit continued to work hard at
several low-paying jobs to ensure that her son
would be able to attend a good college.
Somit initiated the scholarship fund through
a $75,000 bequest commitment to benefit "hard-working and
deserving undergraduate students" in the UB School of Medicine
and Biomedical Science . Deciding he wanted to see immediate
results, Somit has given additional gifts so he could activate the
fund and meet the needs of students like Pratt, who he says is
"precisely the sort of student I had in mind. "
Pratt, whose goal is a career in medicine, was part of a group that
recently returned from a 28-day trek to India led by UB professor of
medicine Richard Lee, MD. Currently, she is pursuing a bachelor of
science degree in medical anthropology and special studies and
expects to graduate in May 2000.
Pratt notes that although her journey to the Himalayas was
exhausting and demanding due to precarious trails and high

CARLOS P ATO, MD, associate professor of
psychiatry and adjunct associate professor of
pharmacology and toxicology, has been appointed associate dean for clinical affairs in the School
of Medicine and Biomedical Sciences.
Pato will work directly with John Wright, MD, dean of the School
of Medicine and Biomedical Sciences, and Bruce Holm, PhD, senior
associate dean, on matters relating to university faculty and programs
within UB's affiliated clinical sites, including clinical research and
space allocation issues within all ofUB's health-care affiliates.
A UB faculty member since 1996, Pato also serves as codirector of
the UB Laboratory of Psychiatric and Molecular Genetics. The lab's
research program focuses on the genetics of psychiatric disorders and
substance-use disorders. The program is funded by the ational
Institute of Mental Health ( IMH ) to study the genetics of schizophrenia and bipolar disorder, and has pilot projects in obsessive
compulsive disorder, alcoholism and substance-use disorder. In
November 1999, it was announced that Pato and his wife, Michele T.
Pato, MD, received a $4.2 million grant from the IMH to search
for a gene(s) that may be linked to bipolar disorder (see page 27 for
more information. )
Pato has received many awards, including a National Research
Service Award and a Young Investigator Award from the ational
Alliance for Research on Schizophrenia and Depression. He has also
published numerous scholarly articles, conference proceedings and

-

LOIS

BAKER

Medical Alumni
Association
Scholarship

altitudes, the knowledge she gained about the health-care challenges
faced by the region's villagers gave her newfound "wisdom and

on, a

-ye· student at

he University at Buffalo School of

endowment fund. Recipients are
selected by the admissions commiHee according to considerations
of financial need and academic
merit based on the incoming

appreciation for both cultural and medical diversity."
While at UB, Pratt has been a volunteer tutor with UB's Learning

Medicine and Biomedical Sciences,

Center and has worked for the past three years in the Office of
CD
Disability Services.

is this year's recipient of the

Originally from Lockport, New

Medical Alumni Association Schol-

York, Eaton is a graduate of Case

ATTENTION STUDENTS

Look for these upcoming events ...
AMA/AMSA Physician-Medical Student
Golf Tournament, Spring 2000
AMSllnnual Residency Fair.lpril2000
More information to come!

20

CD

book chapters.

1 111111 nysiciu

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2000

students' applications.

arship. The scholarship is made

Western Reserve University, where

possible by the

she earned a bachelor of science

generosity of

degree in chemistry. She says her

alumni through
their reunion

long-termgoal is to return to Lockport
CD
:ticem ..

gifts

- S. A.

desig-

nated to the
edical Alumni
Association

UNGER

�Sever"n ,Jo"ns 0

E asAss"stant Dean

CHARLES SEVERIN, MD '97, PHD, has been named assistant dean of
student and curricular affairs for years one and two at the University
at Buffalo School of Medicine and Biomedical Sciences. Severin, who
is a clinical associate professor of anatomy, came to UB in 1981 to
serve as assistant professor of anatomy. Since joining the faculty, he
has been consistently recognized for his service to students and
teaching excellence, having received the Seigel Award as Outstanding
Teacher in Basic Sciences for five years (1982,
1991, 1993, 1994 and 1998). In 1999, he won the
award for residency teaching.
In 1993, at age 46, Severin decided to enter
UB's medical school in addition to maintaining
his teaching responsibilities in anatomy. "I went
to medical school to improve my teaching. I felt
if I had the clinical background I could insert
this experience in my lectures," he says. "Also, I was serving on a
number of committees in which student issues were being discussed
in depth and I wanted to better understand what the students were
experiencing-to be able to better relate to them," he adds.
"Dr. Severin was chosen for this position because of his extraordinary record as a teacher and as a student advocate," says Dennis
adler, MD, associate dean for academic and curricular affairs and
head of the Office of Medical Education (OME). "He is enormously
respected and loved by students, as evidenced by his having been
named recipient of the Seigel Award as many years as he has."
Originally from Youngstown, Ohio, Severin earned his AB degree
in biology in 1970 from St. Louis University, where he also completed his MSCR degree in anatomy in 1972 and his PhD in 1975.
Prior to coming to UB, he was assistant professor of anatomy at the
University of Texas Medical Branch at Galveston.
4D

Rokitka Named
Assistant Dean
MARY ANNE ROKITKA, PHD,
clinical associate professor of
physiology and biophysics, has
been appointed assistant dean
for biomedical undergraduate
education in the School of
Medicine and Biomedical Sci-

ences. She will continue to have
primary responsibility within the
school for developing and overseeing education programs for
undergraduate students potentially interested in careers in the
biomedical sciences.
A faculty member since 1975,
her research involves comparative environmental, animal and
hyperbaric physiology.

New Director of
Student Services

dean for academic and curricular
affairs and head of the Office of
Medical Education. In particular,

of student services in the Office of

he adds, "we wanted to designate

'Jiedical Education lOME) in the

somebody who is not directly in the

School of Medicine and Biomedical

promotion pathway to advocate for

Sciences. She is the first to hold

students and to provide them with

his position, which was created to

assistance and support."
Stamm earned a bachelor of

provide improved support and

arts degree in psychology at the

services to students.
In her role, Stamm serves as a

State University of New York at

student advocate and acts as a

Geneseo in 1992 and a master of

"aison between the student body

education degree in college coun-

and administration. She also is avail-

seling and student personnel ad-

able as a resource person for stu-

ministration at UB in 1995. Prior to

lent clubs and organizations rec-

joining the staff in OME, she was

ognized by Polity.In addition, Stamm

admissions

ill be coordinating the Primary

coordinator in

Care Externship Program (see re-

the Offices of

ated article on page 181 and will be

Admission

orting to implement a new pro-

and Financial

gram called MedCAREERS, a four-

Aid at Har-

ear career planning program cre-

vard Medical
School

ated by the Association of American
Medical Colleges and the American

in

Boston, Massachusetts.

Medical Association to assist medi-

Stamm is available to students

cal students in selecting a specialty.

on a walk-in or appointment basis.

"Our goal in establishing this

She can be reached by phone at

new position in OME was to upgrade

(7161 829-2802; or by e-mail at

theservicesweprovidetostudents,"
says Dennis Nadler, MD, associate

In 1993, she received the
Chancellor's Award for Excellence in Teaching and has been
named an honorary member of
the Mortar
Board and
Golden Key
national
honor societies. She also
received the

o.edu.

Charles W. Shilling Award from
the Undersea and Hyperbaric
Medical Society in 1991 and the
first annual Dr. Mary Anne
Rokitka Award from the Great
Lakes Chapter for the Undersea
and Hyperbaric Medical Society
in 1990.
Rokitka, who has an impressive record of university and
community service, holds two
master's degrees and a doctoral
degree from UB.
- LO IS

\V i 11t er

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2000

BAKER

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2002: Sta eOd sse

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THOMAS

Second·year students form rock band

District,
they rehearse in the basement of a rented house on
Callodine Avenue. There, in a litter of pizza boxes,
beer bottles and backpacks-with a wa her and dryer
for ambience- the members of the rock band
Super-RelateD work out the details of their highenergy contemporary sound. A Marshall amplifier the
size of a filing cabinet blasts out the music as lead
vocalist Andy Swan lets fly with an original song called
"Original Song."
You got to see there isn't a need to get excited
I'm the least of burdens but I hold on, should move on,
That's what I gotta do.
This is medical school?
Well, no. And for the four University at Buffalo

medical school students who make up SuperRelateD,
that's the whole point.
"Most people in class are completely wrapped up in
school," says Mike Campoli, the group's bass player. "I
can't deal with that."
"You can get involved in the
clubs and stuff, but they're still
attached to the school," says Rich
Oh, the band's lead guitarist.
"This is something that's totally
unrelated."
Which is why these four members of the Class of 2002- the
fourth is drummer Dave Krakowski- are manhandling their schedules to make time every Friday afternoon to work on their music. They play cover versions
of pop hits originally recorded by the likes of Mathew
Sweet and eil Young, but they' re also developing a
roster of original songs, actively seeking to play more
nightclubs, hoping to release a CD by the end of the
academic year- in short, putting a lot of nonmedical
energy into the rock-star dream.
Yet it was at school that the idea for SuperRelateD
was conceived, almost by accident. The band members
got together for the first time in January 1998 to perform at the student talent show, which promised to be

22

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a successful debut except for the fact that they didn't
have a drummer. Krakowski, a bassist by training but
quick to pick up other instruments, was nudged into the
breach. "I was elected," he says. "Literally, on the day of
the show, Mike and I went to the music store and
bought a drum set, and I watched an instructional video
that came with it." That night, SuperRelateD closed the
show with a brief set of power rock tunes: cover
versions of Radiohead's " Bends" and Guns' ' Roses'
"Patience." Big dreams were born.
Final exams and the summer break separated the
band for a while, but this academic year they've taken
up the cause with a vengeance. They've recorded a
demo tape, shopped it around to various nightclubs,
and played a live gig at a newly opened club in iagara
Falls. (It wasn' t exactly Madison Square Garden, they
discovered: The owners had put a new roof on the
building and that evening were testing it by dumping
water on it. The roofing job wasn' t great, apparently, as
the ceiling sporadically leaked
water over the band as they
played, inches from megawatts of
microphones, amps and speakers.
They survived.)
For each member of SuperRelateD, their dream requires an
investment of scarce time, not to
mention money. Besides the $600
drum set, they've spent more than $3,000 on amps and
other equipment. "Every time you get something new,
you discover something else you need," Swan says.
But as an antidote to the rigors of anatomy class and
hospital rounds, the band is something they're only too
happy to pursue. One of their more pleasant challenges
is accommodating each performer's tastes in music,
and they're not all that similar. Among their influences,
Campoli cites Captain Beefheart, Lynyrd Skynyrd and
Led Zeppelin; Krakowski listens to AC/DC, Pearl Jam
and modern electronica; Oh is into current British pop
like Stone Roses and the Posies; and Swan loves Pink
Floyd, Queen and the Black Crowes.

SuperRelateD
includes, left
to right, Rich Oh.
Mike Campoli.
Andy Swan and
Dave Krakowski.
Opposite, Andy
Swan. normally
lead smger on
guitar. takes a
turn on drums.

�The band members
As befits a rock band, the musicians are a varied,
eclectic bunch. Swan grew up in the Southern Tier of
ew York, sang in a small a cappella group at Cornell
University, and spent a year after college on the beaches
ofVenezuela. Oh, from Buffalo, played in various bands
in high school and at the University of Chicago.
Krakowski, a ew York City native who'd never played
in a band before, graduated from the State University of
New York at Geneseo, after which he migrated to
Antarctica, where he spent three months doing research.
Campoli played in a band called French Toast at Rutgers
University in his home state of ew Jersey.
But fate brought them together in Buffalo, and only
time will tell how far Super RelateD will go. Two people
who are working to make as much happen as possible for
the band are Charlton Byun, another second-year medical student, who helps out with sound and equipment;
and Dan Yoon, a third-year student in UB's joint MD/
MBA program. Yoon, a versatile musician himself who
has a studio set up in his Amherst home, is acting as the
band's manager and giving advice on technical aspects of
performing, as well as how to approach club owners and
how to construct a crowd-pleasing set of songs.
"They have a very high-energy stage show," Yoon
says. "The songs they choose and the way they play them
is really exciting. They know how to get people going."

Yoon is studying marketing and other management
topics this year, which has played right into his efforts to
develop the band. "I would base a Jot of their marketability on the fact that they're just excellent musicians,"
he says, "which, by the way, is actually pretty common
among medical professionals.
"These guys all love it like I do," he adds, "to the point
where we're all finding the time to approach medical
school from the perspective that although medicine is
going to be our profession, we still need to make time to
do other things we love. And I really think they actually
have a shot. In my opinion, they're as good as any band
I've heard in Buffalo."
Oh, yes, and the name? "The current name,
SuperRelateD, was thought up by Rich during a class
on immunology," Swan says. "And we all agreed it
sounded cool. Originally, we were Val Salva, but we
switched it because we didn't want it to be a medschool pun."
And make no mistake, the band is no joke; its
members are proud of what they're doing and are
seriously devoted to developing their talent in this
creative realm. Says Mike Campoli of their planned
CD: "I want it to happen for us so that someday when
I have kids and they ask, 'Who's this band?' I can tell
them, 'We're the band!"'

Winte r

2000

got together for
the first time in
January 1998 to
perform at the
student talent
show, which
promised to be a
successful debut
except they didn't
haye adrummer.

l• ff a l • n rsi c i u

23

�RESEARCH

ms

N

E

w s

the liver than full-term infants.

president and chief medical

This deficiency could leave them

officer of TRC.
Robert A. Klocke, MD,

susceptible to infection because
of the immaturity of their

professor and chair of the UB

million grant from the Institute

immune system."
Vivien Carrion, MD, and

Department of Medicine, says

for Child Health and Human De-

Linda Duffy, PhD, both of the

the grant "provides a solid base
for us to continue and even to

UB

expand our ongoing research in

University at Buffalo pediatric
researchers have received a $1.2

Work are collaborating with

renal disease."

Upstate New York Transplant
Services, Inc., (U YTS) on a

cal trial of vitamin A's potential
to bolster the immune systems of

Hospital,

Brian M. Murray, MD, UB
associate professor of medicine,

develop ways to increase organ

very premature babies, an action

-LOIS BAKER

Department of Pediatrics
are

co-principal

investigators on the study.

CD

antibody response to the
hepatitis B vaccine, adminis-

who has received early funding

donation in the African American community.

studying the role of growth fac-

The grant is part of a $13
million effort funded by the

Rocco C. Venuto, MD, pro-

tered to all infants at about

three-year, $180,000 grant to

through this grant is currently
tors in the progression of kidney
disease, differentiating between
those that are beneficial and toxic.

The researchers will use

..

Related Professions and Social

and Kaleida Health's Children's

ational Institutes of

that could help prevent poten- .JIIII.if!"!'l'!'!~"'"!'!f'l!'l~~!!!!ll~'--'!lr"!!lii
tially deadly infections.

0

The UB Schools of Medicine
and Biomedical Sciences, Health

Health, to conduct the first clini-

velopment,

.."
..

Organ Donation
Among Minorities
Studied

organ

donation

across

all

one month of age, as an indi-

fessor

cator of vitamin A's immune-

second UB researcher who has

boosting potential. Mark

received TRC grant money,

tor of UNYTS, will be principal

Ballow, MD, UB professor

is conducting ongoing, collab-

investigator on the grant. Judith

of pediatrics and chief of

orative research in the area of

Tamburlin, PhD, UB assistant

the Division of Allergy and

blood-pressure control during

research professor of clinical

Immunology and Pediatric

pregnancy, a topic he has been

laboratory sciences and anatomy

direct the study.
Vitamin A's role as a modula-

segments of the population.
Mark Simon, executive direc-

exploring for nearly 25 years.

and cell biology, will be project

Nephrology
Rese rch Endowe

"If we can understand the role
of the kidney in controlling blood

director and coinvestigator.
The UNYTS-UB collabora-

Rheumatology at Kaleida Health's
Children'sHospital of Buffalo, will

of medicine and a

National Organ and Tissue
Donation Initiative to increase

Total Renal Care, Inc., (TRC) has

pressure, then we can become

tion in the first year of the grant

tor of the immune function has

donated $500,000 to the Univer-

better at avoiding hypertension

will be aimed specifically at the

been studied in both animals and

sity at Buffalo School ofMedicine

and perhaps at saving the lives of

humans, and results have shown

and Biomedical Sciences to es-

pregnant women and preventing

that it is essential for supporting

tablish the Nephrology Research

premature births," he says.

the immune system against infec-

Endowment Fund to partner with

Total Renal Care Holdings,
Inc., headquartered in Torrance,

tion, according to Ballow.

UB in the battle against kidney

"Despite many improvements in

disease. "We are proud to sup-

California, is a provider of inte-

recent years in treating very-low-

port the endeavors of our partner

grated dialysis services for patients

birthweight preterm infants,

institutions like UB, which was

suffering from chronic kidney

infection remains a major problem," he says. "Preterm infants

chosen because of the strength of
its academic program and its

failure, also known as end-stage
CD
renal disease.

have lower levels of vitamin A in

excellent research," says Stan M.

- SUZANNE

their blood and lower reserves in

Lindenfeld , MD, senior vice

"IF WF CAN UNDERSTAND THE ROLE OF THE KIDNEY L

CHAMBERLAIN

CONTROLLING BLOOD PRESSURE,

THEN WF CAN BECOME BETTER AT AVOIDING HYPERTENSION AND PERHAPS AT SAVING THE
LIVES OF PREGNA ••T WOMEN AND PREVE 'TING PREMATURE BIRTHS."

l 1 1f al1 Hysicin

Wi11ter

2000

�African American community.
years of the grant, the emphasis

biology in the UB School of
Dental Medicine.
By exposing mouse

will be on increasing organ

pre·osteoblasts and fully

During the second and third

donation in the Western

ew

York Hispanic and Native American communities, respectively.
Statistics compiled by U YTS
show that in Buffalo, 50 percent
of patients needing organ transplants are African Americans,
while the consent rate for donation from this ethnic group is
only 14 percent.
This low donation rate poses
problems on two accounts: It
limits the number of organs available in general to a population in
which the need is great; and it
decreases the possibility of obtaining a compatible match. Rejection
rates for African Americans are
higher when the organ is from a
donor of another race.

4D

-LOIS BAKER

Melatonin Linked
to Bone Crowth
University at Buffalo researchers
have shown for the first time that
melatonin may play an important
role in promoting bone growth.
The study was conducted by
Jerome A. Roth, PhD, professor of
pharmacology and toxicology in
the UB School of Medicine and
Biomedical Sciences, and Moon·ll
Cho, PhD, professor of oral

differentiated rat osteoblasts
to melatonin, the researchers
were able to show that normal
body levels of the hormone
sped up the transformation
of pre-osteoblasts to fully
differentiated osteoblasts
and induced both types of cells
to produce increased amounts of
several bone matrix proteins
responsible for bone formation.
"After binding to its receptor
on the cell surface, melatonin signals the cell to produce and mineralize bone matrix proteins," Roth
says. ''This has not been shown
before, and we are now investigat·
ing what cellular events are taking
place to make this happen."
"We know melatonin decreases
with age and that bone loss, which
can lead to osteoporosis, is an
inevitable part of aging, especially
among women," Cho says.
"Can melatonin help prevent
osteoporosis? Our research indicates it may have that potential."
Under standard growth conditions in vitro, mouse pre·
osteoblasts undergo cell differentiation to osteoblasts and mineralization in 21 days. Roth and Cho
showed that in the presence of
melatonin, cell differentiation was
completed by day 12 and was

Exercise a Cood
Workout for
..Ju enile
t
ew research on the effects of
exercise on juvenile arthritis indicates it is OK-advantageous, in
fact-for these kids to be kids.
Children with juvenile arthritis who took part in an eight-week
individualized program of resistance exercise at the University at
Buffalo significantly improved
their ability to function, some by

equivalent or greater at that point
than cells grown for 21 days.
Most significantly, says Roth
further experiments showed that
the mouse pre-osteoblasts responded to normal body levels o
melatonin, but the cells needed
to undergo five to seven days of
differentiation before they were
capable of responding to melatonin at that level.
"These findings place melatonin with a select handful of other
agents-includingglucocorticoids,
bone morphogenic proteins and
vitamin D-that are known to
stimulate mineralization in osteoblasts," says Roth.
"Because melatonin levels
decrease during the aging process,
the possibility must be considered
that melatonin may have a significant influence on the rate of synthesis and maintenance of bone in
the elde ly.
-LOIS

as much as 200 percent, as shown
in preliminary results of the
study. Equally important, their
pain, disability and use of medications decreased significantly.
The research was
conducted by adine
Fisher, EdD, assistant
professor of occupational therapy and
rehabilitation medicine, with support from
the ational Institute
on Disability and Rehabilitation Research.
In
ovember 1999,
she presented results of

eexpected to
see achange in the
disease with
exercise, but we
didn't expect to
ee so much,"
says Fisher.
Everybody
showed
tremendous
hysiological
·mprovement.''

the study in Boston,
MA, at a joint meeting of the
American College of Rheumatology and the Association of Rheumatology Health Professionals.
"We expected to see a change
in the disease with exercise, but
we didn't expect to see so much,"

BAKER

says Fisher. "Everybody showed tremendous physiological
improvement-better strength,
endurance and even better
aerobic capacity, although these
exercises weren't designed for
that. Everyone had less pain.

~NTINUED

Winter

2000

ON

PAGE

26

1111111 Hysicill

25

�N

RESEARCH

....
..

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w s

Res arch Institute
on Add"ctions
"oins UB

sion of hepatitis C. RIA scientist!

The Research Institute on Addic-

addictive gambling, one involvin

tions (RIAl, formerly a component

a nationwide survey of gamblin

..

I~N TI N UEO

behavior and alcohol use, and the

Alcoholism and Substance Abuse

second evaluating coping skills in

Services (OASASI, became part of

individuals who have partners who

University at Buffalo on November

are pathological gamblers.

PA G E 25

at the institute at 1021 Main
Street in Buffalo, New York.

lished at UB in 1968 by the state
Department of Mental Hygiene to

ally for its research on the develop-

conduct research into alcoholisn

" Some kids showed 200percent improvement," she adds.
"That's pretty exciting."
Fisher designed the exercise

ment of substance-abuse problems

and potential treatments. Cedric

and the prevention and treatment

Smith, MD, UB professor of phar

of substance abuse. The institute

macology and toxicology (see be

umps $8.1 million a year in exter-

low), was RIA's first director, serv

program and has shown its

al research funding into the local

ing unti11979. Through a series of

conomy, in addition to expending

changes in administration, both at

benefits in previous studies of
elderly patients with osteoarthritis. However, until now, an
individualized resis -

The sho
examined t
nature. prevalenc
and consequence
of complete
memory lapsesso-cane

tance exercise program
had never been tried
with children.

a state budget of $3.1 million.

other researchers around the
country-have found to be a
relatively common occurrence.
Specifically, Smith was asked
to describe the results of studies
he has carried out in collaboration with Cynthia Pristach, MD,
clinical associate professor in
UB's Department of Psychiatry,
in which they examined the
effects of blackouts on subsequent drinking in both moderate
drinkers and alcoholic patients.

under the administrative jurisdiction of OASAS, although the two

Characteristically, indjviduals

ill retain its identity and remain

institutions maintained close re-

experiencing blackouts don't
realize they have had memory
loss until hours or days after

n its present location. Gerard J.

searc

c ional ties.

4D

- LOIS BAKER

research professor of psychology,
said of the transition: "We are
delighted with our merger with the
niversity and are excited about
he new opportunities that will re-

20,20 Features
Cedric Smith as
Exp rt on Alcoholic

ultfor both RIA and UB." Connors
id the institute will continue to
ocus its research on alcohol and
other substance use and abuse
and that it has expanded it
emphasis to include compulsiv

inflammatory compounds.

infant development in alcoholi

-

families; ways of reducing DWI rc

ambling. Current RIA researcl
·ncludes investigating alcohol us
in early marriage; parenting an

cidivism; skills training for parent
of adolescent drug abusers; an
heavydrinking,druguseand blood
to-blood transmission betwee1

lllfall nysieiu

least 10- 20 percent of the population. The interest in blackouts stems in part from apparent
skepticism on the part of
the public regarding what Smith
and his colleagues-as well as

RIA will function as a free-stand-

controls at baseline and that the
exercise program significantly
decreased these cytokines and
increased production of anti-

LOIS BAKER

UB and at the state level, RIA moved

particularly interested in establishing that blackouts not only do
occur, but are experienced by at

ing research institute within UB and

onnors, RIA director and UB

An accompanying
investigation conducted
by )aya Venkatraman,
PhD, associate profes~blackouts"­
sor of nutrition, found
that can occ
that children with
with alcohol juvenile arthritis had
higher concentrations
of pro-inflammatory cytokines
in their blood than normal

26

The merger brings RIA back to
its roots. The institute was estab

RIA is recognized intemation·
FROM

recently began two projects or

of the New York State Office of

18, 1999, during ceremonies held

•

sexual partners in the transmis

Wi11t e r

2 000

The October 18, 1999, edition of
the ABC television news program
20/20featured Cedric Smith, MD,
professor in the Department of
Pharmacology and Toxicology, as
an expert on memory disturbances produced by alcoholic
beverages. The show examined
the nature, prevalence and consequences of complete memory
lapses- so-called "blackouts"that can occur with alcohol consumption. Smith was interviewed
by Cynthia McFadden, who was

recovery from the intoxication,
according to Smith. Furthermore,
although alcoholic patients
(approximately 70 percent) often
suffer repeatedly from blackouts,
the episodes are not limited to
alcoholic individuals. "The particularly puzzling and frightening

�aspect of blackouts is the fact that

a $2.6 million project also funded

the individuals appear to have an
intact memory and can act 'nor-

by the IH, now entering its
third year.
"Although a genetic linkage
has been presumed to underlie
bipolar disease in many individu-

mally' during the time period that
they subsequently can't remember," says Smith. "Fortunately,
some individuals appear less susceptible to blackouts than others."
Currently, Smith and his
colleagues are preparing to
publish new data they have gathered from their studies on
alcohol-induced blackouts. CD
-S.A. UNGER

$4.2 Million Crant
to Study Cenetics
of Bipolar Disorder
Carlos . Pato, MD, and Michele
T. Pato, MD, associate professors
of psychiatry and co-directors of
the Laboratory of Psychiatric
and Molecular Genetics at the
University at Buffalo School
of Medicine and Biomedical
Sciences, have received a $4.2
million grant from the ational
Institutes ofHealth to search for a
gene or genes that may be linked

.

....
..

to bipolar disorder.
Identifying the molecular basis
of such a linkage could lead to
advances in diagnosis and treatmentofthe disorder, which affects
millions of people worldwide .
The husband-and-wife team
are conducting their research with
the relatively homogeneous population of the Azores, Portuguese
islands located in the North
Atlantic about 1,000 miles off the
coast of the Iberian Peninsula.
This same population forms the
study base for their search forgenetic markers for schizophrenia,

als, this research promises to
reveal the molecular basis of that
linkage, and may well lead to
important
diagnostic
and therapeutic advances," says

months. Persons in the manic

Pato explains. "In addition, the
Azores have a centralized health
system, and alllO psychiatrists on

phase of the disorder can be psy-

the islands are collaborating on

chotic, are easily distracted,
experience exaggerated feelings
of well being, exhibit inflated

the project."
The researchers will look for
hereditary pathways of the disease using a variety ofapproaches.
"We will select genetic markers

be cyclic, with sufferers remaining manic or depressive for

self-esteem and may indulge
extravagantly in irrational activities. In the
depressive
phase,
persons ex-

and look at how the markers behave in well families, compared
to a family where the illness shows
up several times," Patosays. "We'll

perience inertia, loss of
self-esteem,
withdrawal,

also look to see if illness and

Biomedical

sadness and
may even be

we'll develop a description of
each suspect gene and determine

Sciences.
Carlos

suicidal.
Present

how often it occurs
with illness."
An important aspect of the study will be
a haplotype relativerisk analysis. Using this
approach, researchers

John Wright,
MD, dean of
the School of
Medicine and

Pato, principal
investigator on this research
project and associate dean for
clinical affairs in the medical
school, says bipolar disordercommonly referred to as manic
depression-affects about 0. 7
percent of the worldwide population, with a large percentage having a possible genetic component.
"The most consistent and signifi-

treatments for
bipolar disorder focus on managing these symptoms. The Patos
say they hope that uncovering the
genetic etiology of these disorders will be an important step in
developing improved treatments
and, possibly, specific cures.
Through a pilot study, the researchers already have identified
25 families with 84 affected mem-

cant risk for developing bipolar
disorder or schizophrenia is

bers. That population will be
expanded in the newly funded

being related to a person suffering from the same illness," he
says. "Though it is likely that

five-year investigation to include
225 persons with bipolar disorder
and their parents. A third study
group will be composed of all
other Azoreans with the disorder.
"The Azores are ideal for a

nongenetic factors play an important role in the expression of
these illnesses, a significant
portion or risk must be genetic."
Bipolar disorder is characterized by dramatic mood swings
between mania and depression.
The mood swings develop and
subside spontaneously and may

genetic analysis because the
islands are geographically isolated and the population has
remained relatively homogeneous, with most inhabitants
descended from a few families,"

Winter

genetic markers co-exist and
analyze genetic patterns from ill
person to ill person. In addition,

Mllthough a
11enetic linkage
as been
resumed to
derlie bipolar
sease in many
ividuals, this
will analyze the set of
esearch promises
genes from a patient's
oreveal the
parents that were not
olecular basis of
passed on to that that linkage, and
patient, with the nonay well lead to
inherited set then
nponant
acting as a control.
iagnostic and
Both researchers therapeutic
hold adjunct appoint- advances."
ments with the Center
for euroscience at the UniversityofCoimbra in Portugal, which
is collaborating on the project.
The Whitehead/MIT Center for
Genome Research will perform a
genome-wide scan and collaboCD
rate on all data analysis.
-LOIS BAKER

2 000

laffale Hysicin

27

�S

T

U

D

E

N

T

COLUMN

Sendin Out an S.O.S.

BY
H

A

N

A

C

H

0

E

Students Offer i ng Support Peer Group Established

yet
I stared at the clock as if it
were alien to me. I just
wanted it to stop bothering me so I tried willing it
to be silent. Finally,
itsincessantnagging
forced me to drag
myself across the
room to turn it off.
I had classes.

....

28

l11falt Hysiciu

Though the morning
sun streamed through
the window blinds heralding a new day, I convinced myself that it
would probably be too
cold, or classes would be
boring, or that I could
read and study on my
own and, oh, that I wasn't
feeling too well either.
This day was just not a
good day.
I crawled back into bed, relieved that I had been
able to rationalize my way out of going to school.
Perhaps I was getting sick; it was winter in Buffalo,
ew York, after all. Maybe I had hypothyroidism;
hadn't we just learned about Hashimoto's thyroiditis
and the concomitant lethargy? Surely, there was a
physiological explanation. Yet, in the back of my
mind, in my heart of hearts, I knew it was something
else: I was depressed.
But how could I be? I had always been a proactive,
strong, independent soul with high ambitions and
strict control over all aspects of my life. While at
Columbia University as an undergraduate, I had been
vice president of my senior class and felt I had a bright
future. Following graduation, I took time off to

Winter

2000

prepare for medical school, get some experience in the
work force, and earn a master's degree in biology at
ew York University, to boot.
Accomplishment, scholarship and leadership had
not been foreign to me. But now I felt trapped in a
futile struggle against apathy towards school, career,
life. And in the vicious cycle of life's quirks, the less I
cared, the worse I performed in school and the worse
the situation progressed. It was as if I had been
performing all along and, now, I could not muster the
energy or desire to go back on stage anymore.
I needed help, but did not know where to turn.
Approaching a dean seemed intimidating, and friends
seemed to be having some of the same problems. We
did not have advisors, and I wondered, "Did UB have
counselors specifically for medical students?"
Because several of my fellow students had similar
questions and concerns, we began a quest to find
answers and forge solutions. We decided to get a
consensus ofhow many students were suffering doubts,
fears and emotional stress. Therefore, in March 1999,
we conducted a survey of the classes of 2002 and
2001. Some sobering facts were revealed: 62.1 percent
of the 120 students of the class of 2002 and 69.7
percent of the 85 second year students in the class of
2001 who responded said they had experienced a
period of significant psychological and emotional
distress at least once since attending medical school.
These statistics confirm the trend that during
medical school training, while students are taught to
empathize with, diagnose and treat patients, our own
physical, mental and emotional health suffers.
We further found that almost a third of the class of
2002 (43 students) and a quarter of the class of2001
(31 students) were distressed enough to need help
or counseling. More disturbing is the fact that these
medical students-typically characterized as bright
and intelligent, motivated and achievement
oriented-did not know where to turn for help.
What will medicine be like in the next millennium
if medical students today cannot obtain help to maintain their own health and happiness? The reality is that

�A RECENT ARTICLE

IN NEWSWEEK ... TITLED «THE SILENT

A1

GUISH OF THE HEALERS"

ADDRESSES THIS CYCLE THAT EVENTUALLY MANIFESTS ITSELF IN THI:. DETERIORATION OF
THE PHYSICIAN-PATIENT RELATIONSHIP AND, INCREASINGLY, IN MALPRACTICE LITIGATION.
the problem stems not from a lack of coping abilities,
but because there is often a stigma attached to medical
students and physicians who admit they need help;
it's as if we were admitting a weakness. The awesome
responsibility of caring for the people in our community and the fiduciary expectations placed on
physicians can be not only intimidating but debilitating, especially when shouldered by clinically naive
medical students. However, to concede that we cannot
handle adversity not only forces us to relinquish
control of a situation, but exposes a fallibility that is
not allowed. Hence, it is safer to assume the pretense of
unyielding strength and flawless competency.
Moreover, the Marcus Welby phenomenon traps
us and transforms us into demigods in the eyes of our
families, friends and communities. How then can we
possibly admit we need help? It is one thing to cope
with the vicissitudes of life in our own personal lives;
it is quite another to be defined by our career and to
play a role that is immune to doubts, fears and tragedy.
Physicians may become captives of the emotional
and psychological duress associated with caring for
the health of entire communities, which involves
confronting pain and death at every step. Ironically,
as administrators of health care, we are trained to
recognize the signs that a patient's health is compromised, yet we ignore these same signs in ourselves.
Would it make us too vulnerable if we remembered
that we are in fact only human? If we do not tend to
ourselves, we cannot fully and sincerely attend to our
patients. A recent article in Newsweek (September 13,
1999) titled "The Silent Anguish of the Healers"
addresses this cycle that eventually manifests itself in
the deterioration of the physician-patient relationship
and, increasingly, in malpractice litigation.
My peers and I refuse to accept this state of affairs
and are endeavoring to change it. As a result, in April
1999, we established a student-run peer support group
called S.O.S., for Students Offering Support. Through
sheer determination and dedication we have initiated
a program-the first of its kind at UB-that will
promote the health of the medical student body.
Though our group is still in its infancy, its mission is
centuries old and found throughout the animal kingdom: We must take care of our own if we expect to

survive. If we medical students and future doctors
are to work together on the wards, in teams and
in group practices, we must work together to preserve
the sanctity of our collective well being.
Therefore, S.O.S. reaches out to students by offering education and peer support on four levels. The
first level of support includes a resource center that
provides information on service agencies in the community and a lecture series that addresses issues such
as stress reduction, family planning and seasonal affective disorder. With prevention as the
trend in health care for the millennium, our responsibility is to
educate not only our patients,
but ourselves and our peers.
The second level of support is
a pager service offered daily for
direct and immediate peer support and referrals. As one S.O.S. member states, "I
believe that an S.O.S. volunteer can demonstrate the
same personal attention and compassion on the phone
that a physician would show during a face-to-face
visit." It's inspiring that students are concerned enough
for fellow students that they will take time out of their
busy schedules to be on call for others.
The third level of support maximizes the benefits of
group discussions to further examine issues like
maintaining relationships and exploring spirituality
throughout a medical career. Finally, the fourth level
is the bridge to professional therapists and psychiatrists. By matching medical students with psychiatrists
in the community, we are encouraging them to seek
help when they have problems.
And now, almost a year has passed since that morning I lay in bed, willing my alarm to cease its noise. I
admit I am still anxious about the challenges ahead.
However, I do know there is strength in numbers; I
will support and be supported by my peers. I encourage
4D
you to do the same by sending out an S.O.S.

For more information on S.O.S., visit the group's website at
http://www.smbs.buffalo.edu/polity/sos.

What will medicine be
like in the next
millennium if medical
students today cannot
obtain help to maintain
their own health an
happiness? The reality is
that the problem stems
not from alack of coping
abilities, but because
there is often astigma
attached to medical
students and physicians
who admit they need
help: it's as if we were
admitting aweakness.

{ana Choe zs a second-year student at the Uni~erstty at
Buffalo School of Medicme and Biomedical Sciences.

Wi11ter

2000

1111111 Plysicill

29

�N

E

w s

"Can You B

•

By Li nda J . Cor de r , PhD, CFRE

on my birthday,
about a decade ago. His eyes were intense but kind as he
welcomed me to his kingdom, the Department of
Medicine at St. Louis University's School of Medicine.
Obviously a benign monarch, he offered me heartshaped cookies baked by one of the office staff for
Valentine's Day. While he went to find coffee, I
explored the landscape of his office, noting that the
walls were covered with a lifetime of honors. These
included a citation of appreciation for his term as
president of the American College of Physicians, hung
not far from his UB diploma.
Tom was also in charge of graduate medical education. On a tour of St. John's Mercy Medical Center,
everyone we met grinned in response to his quiet
greeting. Along the way, he indulged my obviously
nascent knowledge of the field of medicine by explaining the various stages of medical education and training. Tom also fervently extolled the virtues
of music, literature, art and "living life."
We ended our sojourn in the library, where
a large oil painting of him was propped
against a set of shelves. "When you next
visit," he said shyly, "that will be hanging;
the library was recently named for me."
Over the intervening years, Tom shared
more stories about his life. I learned that
he is a spouse, a dad, and a man deeply
involved in his community. He also plays
the piano, reads widely and enjoys excelling at golf.
Driving down Buffalo's "memory lanes" a few years
ago, Tom described to me his UB days, which were
spent mostly at the hospital because he lived in a house
in Allentown where the heat seldom made it to his
third-floor room. As a result, the residents dubbed him
"that student who hangs around."
One night, he recalls, a woman was brought into the
ERin a coma and he was encouraged to observe as an
"amber-colored fluid" was injected into a vein. The
patient immediately awoke and asked where she was.
"To a kid, this seemed like magic, or a true miracle,"
Tom remembers. Later, he learned that the woman had
been in Addisonian crisis.

30

l 1 fla l1 H ysi c i11

Winter

2000

Tom was in the hospital that night because his room
was freezing, a fortuitous circumstance that changed
his life, as he made up his mind then and there to
dedicate his energies to the study of Addison's disease.
When he completed his residency, Tom's dream
was to conduct research with George Thorn, a UB
graduate known for his seminal work in endocrinology. After interviewing Tom in Boston, Dr. Thorn
decided he would be a welcome addition to his lab;
however, due to funding, he had to delay offering him
a fellowship for a year. Fearful that a dream deferred
would never come to pass, Tom returned to Buffalo
broken-hearted.
A group of faculty-Jed by Dr. John Talbott-told
Tom, "We will finance your first year of research until
Thorn can provide fellowship funds." Recalling this
offer, Tom asked me with unmitigated awe, "Can you
believe that?" The UB faculty encouraged Tom to
"learn and return" but didn't hold him to
an agreement when he was offered "a rank
and salary UB simply couldn't match."
His mentor said, "We want what is best for
you, so take it." Again Tom said to me,
"Can you believe that?"
Recently, Dr. and Mrs. Frawley completed funding an endowment that will
enable other young physicians interested
in research to pursue their dream.
This story is not just about the Thomas
Frawley, M. D. Residency Research Fellowship Fund,
although it will make a difference to the school forever.
What strikes me as amazing is the aspect of
Tom's story that pertains to his decision to embark
upon a career in medical research and how dedicated
professors and an outstanding UB alumnus worked
together to effect a remarkable outcome. It also shows
how "serendipitous" can become "likely" when people
and resources are dedicated to students and to creating
an academic environment that exceeds expectations.
Lyn Corder is associate dean and director of development.
She may be reached by phone, toll free, at 1-877-826-3246,
or by e-mail at ljcorder@buffalo.edu.

�Spring Clinical Day and
e nion Weekend 2000
Mark your calendars

I

Cass of 1955

t's not too early to plan for the 2000 Spring Clinical Day and
Reunion Weekend.

John H. Peterson

A cocktail reception will be held Friday, April28, 2000. The

Ray Schiferle

63rd Spring Clinical Day and Reunion Dinners will be
on Saturday, April 29. For more information, call the Medical Alumni
Association at (7161 829-2778.

John H. Peterson

The reunion classes are 1945, 1950, 1955, 1960, 1965, 1970,
1975, 1980, 1985, 1990 and 1995.
Here's what your reunion chairs have to say . . .

Admit it, you've stayed away too long! Come
enjoy Spring Clinical Day activities and our
45th reunion. The clock is ticking, so plan
to attend. Details very soon. -Ray

Class of 1945
Herbert Joyce

Herbert Joyce

Ray Schiferle

We encourage all of those of the Class
of' 45 who are still able to come to attend
our 55th reunion. The festivities will be
the grandest yet for the double nickel
on 4/29/2000.

Class of 1950

Class of 1960
James Kanski
RogerDayer

]ames Kanski

Sidney Anthone

Save thedatesApri128 and 29,2000. It's our
50-year class reunion and great plans are
being made to make it a monumental event.
You will be hearing from us about further
details. Call your closest classmates and
start planning to share the event. Please let
us know of any ideas you may have to make
the occasion even more special.

Plan now for our May 2000 reunion. It's
time to renew old friendships, reminisce
and share a few laughs. -James
Hope everyone will join us for our Can-Am
celebration of our 40th. -Roger

Bob Patterson

Sidney Anthone

In '95 we had a great time with 20 classmates. Let's try and double that for our
45th. You wouldn't believe all the tales
traded about. Please try and make it.
-John

Roger Dayer

Bob Patterson

Wi11ter

2000

1111111 Plysiciu

31

�S

P R. I

G

C

IC'AL

Ll

DAY

AND

REU

10

WEEKEND

c sso

5

2000

985

Beth Maher

Joe Cardamone

Jack Coyne

Joe Cardamone

It really has been 35 years since graduation.
Let's all get reacquainted. I look forward to
seeing you at our reunion weekend
April 28-30, 2000.

Come and join us in the "City of Light" in
the spring of the new millennium.
Beth Maher

970
Don Copley

Don Copley

Be sure to reserve the dates for our 30th
medical school reunion in April. Andrea
and I look forward to seeing you. If you
attended our last reunion, you'll recall the
fun we had reminiscing, comparing
career twists and reviewing life's little
adventures. And don't forget to bring
along some belly laughs!

Jack Coyne

s 990
Ray Paolini

Ray Paolini
John C. Stubenbord

John C.
Stubenbord

On April 29, 2000, we will be celebrating
our ten-year reunion. Please mark your
new 2000 calendars now and share with
your classmates some fond memories of
good times.

It's been 25 years since we were all together
in Buffalo. Come on home to the place of
our medical beginnings. Hope that you all
can return for April 29, 2000.

95
Martin Mahoney
Tara Sosa Paolini

Margaret W. Paroski

Martin Mahoney

Let's begin the new millennium by renewing old friendships.
Margaret
W. Paroski

Tara Sosa Paolil1i

3 2

l 1ffal1 Hysicin

Wtnter

2000

Let's get together to catch up! Plan to join
us for our five-year reunion .... Hope you
can attend.

�Dear Fellow Alumni,
I have been privileged to participate in many
interesting and exciting events over the past few months.
In mid-September, Dr. john Bodkin, vice president of the Medical Alumni Association, chaired the
reunion chairs' dinner, held at the Transit Valley Country Club. Dean Wright spoke, and we had a chance
to meet with the chairs of the individual reunion classes that will be held in April 2000. It was a welcome
opportunity for us to meet these volunteers and show our appreciation for their stepping forward to chair
their respective reunion dinners.
Later in September, the past presidents' dinner was held at the Buffalo Club in downtown Buffalo. At this
event, we were pleased to present the Distinguished Medical Alumnus Award to Dr. Robert Reisman in
honor of his many contributions to allergy and immunology and to our medical school. In
accepting the award, Dr. Reisman gave a wonderful talk about his career and his thoughts on
the past, present and future of medicine.
On October 9, 1999, I was privileged to speak before the Parents' Guild during Parents'
Week for the first-year medical students. The Parents' Guild is an impressive organization that
has been established to try to improve aspects of the medical education experience. This was
a well-organized day that gave the parents an opportunity to visit the classrooms, meet the
professors and see where their children are learning the basic sciences.
The Physician-Student Mentoring Program got off to a rousing start this year under the direction of
Dr. Stephen Pollack, who was successful in matching 140 physicians one-on-one with medical students. The
goal of this program is to provide students with a nonacademic advisor who can be available on an informal
basis to answer any personal or professional questions they may have.
Dr. Anthony Markello has volunteered to chair the Community Physicians Speakers Program. In this
program, the Medical Alumni Association arranges for physicians in the community to come and speak to
first- and second-year classes to help acquaint them with the hours and dedication needed for the various
fields of medicine.
We have begun to plan our fourth-year medical student reception, held each spring and sponsored by
the Medical Alumni Association. The reception, which will be chaired this year by Dr. Bodkin, is a splendid
annual event in which the fourth-year students and their significant others come and celebrate the close of
their medical school experience.
Finally, plans for Spring Clinical Day 2000 are beginning to take shape. The theme for the day will be
"Children's Health," and our Stockton Kimball lecturer, as announced in the last issue of Buffalo Physician,
will be Maxine Hayes, MD '73, assistant secretary of community and family health for the Washington State
Department of Health. Dr. Bruce Rogers, head of the Division of Maternal-Fetal Medicine at Kaleida
Health's Children's Hospital, has also accepted Dr. Colleen Mattimore's invitation to participate in the
program. Other speakers have been invited, and we are awaiting their response.
This is an exciting time to be on the Medical Alumni Association's board. If you are interested in joining
our board, please drop me a line through the Medical Alumni Association office at 101 Cary Hall, or call the
office at (716) 829-2778.

RICHARD

L.

COLLINS ,

MD

President, Medical Alumni Association

Winter

2000

l11fale Hysicin

33

�CLASS

1940s
Ralph T. Behling, MD '43,

My wife, Rita Clancy
Behling, died in July
1998. I remarried in
August 1999 to California widow with five
children.
Jacqueline Paroski, MD '49,

North Tonawanda, Y,
Pediatrics. "Julie Cullen
and I were the first
women interns at the
Millard Fillmore Hospital. We were also
among the first women
physicians in the U.S.
Navy. I was the first
woman president of the
medical staff of the
DeGraff Memorial
Hospital and first
woman to be head of
pediatrics at DeGraff."
John Sharp, MD '49,

Holmes Beach, FL,
Internal Medicine.
"From 1959 to 1987 I
was chief of cardiopulmonary medicine at
Hines VA Hospital near
Chicago, IL. I was also
professor of medicine at
the University of Illinois
and Loyola University in
Chicago. I did research
in cardiorespiratory
physiology and was associate editor of the fota-

nal of Applied Physiology
in the 1980s for five
years." jacksue@gte.net

34

NOTES

rics/gynecology at the
University of Mississippi
from 1967-1974; assistant/associate dean of
Academic Affairs at the
University of Mississippi
from 1970-1974; and
chair of obstetrics/
gynecology at the
University of Rochester
(NY) from 1974-1995.
I am now retired."
thiede@rochester.rr.com
Irma Waldo, MD '49,

Hillsdale, NY, Pediatrics/
Primary Care. "I have
skied for 40 years and
am serving on the ski
patrol at the Catamount
ski area in Hillsdale, NY.
In addition to private
solo practice, I have
always done school
health, and with the
County Health Department held well-baby and
immunization clinics. In
semi-retirement. I was
attending MD and
medical director of our
county nursing home
and Twin County Alcohol and Substance Abuse
Services of Columbia
and Greene counties."

1950s
Eugene Beltrami, MD '54,

Williamsville, NY,
Obstetrics/Gynecology.
"I am director of Medical Legal Affairs for the
Department ofVeteran's
Affairs nationwide."

Henry Thiede, MD '49,

Jacob Lemann Jr., MD '54,

Pittsford, Y, OB/GY
"I was chair of obstet-

ew Orleans, LA, Internal Medicine. "I was an

l tffal• Hysici11

Winter

2000

instructor in medicine at
Boston University
School of Medicine from
1961-1963; assistant/
associate professor of
medicine at Marquette
University School of
Medicine in Milwaukee,
WI, from 1963-1968;
associate professor and
chief of Nephrology
Division at Boston
University School of
Medicine from 19681970; professor of medicine and chief of nephrology at the Medical
College of Wisconsin
from 1970-1990; clinical
professor of medicine
(part-time), Tulane University School of Medicine in New Orleans,
LA, from 1995-present."
J]emannla@aol.com
Ernest Meese, MD '54,

Cincinnati, OH,
Cardiothoracic Surgery.
"My first wife, Marge,
was killed in auto accident in 1984 (32 years of
marriage). I remarried
Rockell Dombar in 1985
and in 1992 had twins
Matthew and Donyel,
now seven years old. I
am still actively practicing thoracic surgery in

Cincinnati, where I have
lived for 34 years. I am
active in state and local
American Cancer
Society and am a lifetime board member."

Thaddeus Reszel, MD '54,

Robert Dshrin, MD '54,

Buffalo, NY. "I am with
Buffalo Amherst Allergy
Associates, Department
of Internal Medicine,
Rheumatology and
Hepatology and senior
partner of a fivephysician allergy/
immunology practice.
Also, president of the
ew York State Society
of Allergy and Immunology from (1997-1999).

orth Tonawanda, NY.
"I am in part-time office
practice at Reszel Family
Practice."
John Kent, MD '55,

Hackettstown, NJ,
Obstetrics/Gynecology.
"I have been golfing,
traveling, reading, relaxing for the past 13 and a
half years of retired life."
Joshrin@worldnet.att.net
Robert Pletman, MD '54,

Schenectedy, NY, Urology. "I am president of
Schenectady Urologic
Associates. I served 18
years as chief of urology
and five years as chief of
staff at St. Clares Hospital. I am active as a
hospital trustee."

E-mail

BernardS. Shapiro, MD '57,

writes: "I was forced
to retire from general
surgery due to a knee
injury, and moved to
ashua, NH, to live
closer to our four grandchildren and their
parents. I've done some
teaching of medical
ethics to seniors at an
institute of learning in
retirement. I also work
CONTlNUED ON PAGE 36

�In Memoriam

Kenneth H. Eckhert, Sr.
MD '35, a member of the
School of Medicine and

James E. Long, MD '31,
a fonner faculty member
in the School of Medi·
cine and Biomedical
Sciences, died November
10, 1999, one day
before his 93rd birthday,
in Buffalo General Hospi·
tal after a brief illness.
Long, who joined the UB
faculty in 1946, received
a bachelor's degree from
UB in 1924 and gradu·
ated from the UB medi·
cal school in 1931.
During his career, he
established a private
general-medicine prac·
tice on Parkside Avenue
in Buffalo and also was
affiliated with Buffalo
General Hospital as an
associate physician.
When he retired in 1977,
he was awarded a
Citation of Professional
Medicine by the UB
medical school. A vet·
eran of World War II,

Biomedical Sciences' clini·
cal faculty for more than
40 years, died November
26, 1999, in his Buffalo

was boarded in radiology,
radiation therapy and

can Cancer Society and

berg earned bachelor's and

nuclear medicine and

was working to build a

master's degrees from the

quality assurance. His

network of patient advo·

University of Buffalo before

passion was for making a

cacy centers around the

difference in the treat·

country. He had been

. entering the Anny in 1942.
After the war, he briefly

ment of breast disease

honored by Los Angeles

studied psychology at the

and, to this end, he

County and the cities of
Los Angeles and Santa

University of Chicago before

helped introduce the use

He was 88. A native of

returning to UB to study

of noninvasive needle

Monica, among others,

Buffalo, Eckhert graduated

medicine. He graduated

biopsies of the breast and

for his contributions to

home after a long illness.

from the University of Buf·
falo in 1931 and from the
university's medical school
in 1935. He served on the
medical school faculty from
1940 to 1981, retiring as a
clinical instructor emeritus.
He received the Dean's
Award from the medical
school in 1968. During his
long medical career,
Eckhert was chief of sur·
gery at Deaconess Hospital
and senior cancer research
surgeon at what is now
Roswell Park Cancer lnsti·
tute. Among his survivors
is his son, Kenneth H.
Eckhert, Jr., MD '68,
clinical assistant professor
of surgery in the UB
medical school.

Long joined the Anny in
1942 and served as a

Committee of the Ameri·

Williamsville home. He was
80. A Buffalo native, Stul·

Gardner Cox II, MD '48, died

major in the 20th Gen·

in June 1999 at age 76 in

eral Hospital, University

Holyoke, MA.

from the School of Medicine

other organs in the Los

health care. He was au·

and Biomedical Sciences in

Angeles area. In 1975, he

thor of a book titled The

1952. After receiving train·

opened one of the first

Multimodality Approach

centers exclusively dedi·

to Breast Imaging and

. Harvard University and Mas·

cated to breast diagnos·

consuHed and lectured

sachuseHs General Hospital,

tics. Called the Women's

internationally on breast

. ing in child psychiatry at

Stulberg returned to

disease, patient·

Buffalo and entered

centered disease

private practice. He

state management

. served as director of

and patient advo·

· the Child and Adoles·

cacy. In addition, he

cent Clinic on three

worked successfully

· occasions and was

with national, state

: honored by the clinic

andlocalheaHhcare
policymakers on

for 37 years of ser·
· vice. He joined the

of Pennsylvania, Unit.

Breast Center, this facility

women under age 50, and

: also worked with the psy·

became a medical blue·

the allocation of tax

. chology department, in·

print and effective busi·

revenues from the sale of
cigarettes for use in

structing clinical students in

ness model for other such

group therapy. Stulberg had

centers that were estab·

breast cancer research.

been a life fellow of the

lished across the nation

Porrath is survived by his

American Psychiatric Asso·

in the following decades.

wife, Toni Bernay, PhD,

ciation since 1967.

Porrath served as presi·

and his three children:

Bunna-lndia Theater

clinical associate professor

and, while stationed in

emeritus of psychiatry, died

India, was awarded a

November 24, 1999, in

commendation for

Millard Fillmore Hospital

research in malaria

after becoming ill in his

dent of The American So·

Mitchell Bernay of Dallas,

ciety of Breast Disease,

TX, Ellen Lord of Buffalo,

The National Consortium

NY, Laura Chalfin of Los

. at his home in Beverly Hills,

of Breast Centers, and

Angeles, CA; and his sis·

· CA. A pioneer in medical

vice president and trea·

ter, Hedria Lunken, and

. diagnosis and treatment of

surer of the International

mother, Tibey Porrath,

· women's heaHh, Porrath

Society of Senology. He

both of Buffalo, NY.

died September 12, 1999,
Burton Stulberg, MD '52,

to mammograms for

: UB medical school
· clinical faculty in 1989. He

· Saar l. Porrath, MD '61,

He served in the China·

legislation pertaining

Saar A. Porrath, MD '&amp;1

was a Fellow of the Ameri·

was a member of the

can College of Radiology

AHernative Medicine

treatment.

Winter

2000

l1ffall Hysitill

35

�CLASSNOTES

parttime now at the
VAMC in Manchester,
NH, doing GI endoscopy
and small surgeries two
days a week. I would
love to hear from my
classmates. n
bernshap@aol.com
Constantine Cretekos,
MD '59, Pi ttburgh, PA,

Child and Adolescent
Psychiatry. "I have
worked at the same
agency for 30 years and
have loved it."
James Doyle, MD '59,

Dana Point, CA, General
Practice-Anesthesiology.
"I am now retired. Recently I was visited by
Dr. Ron Hoyt and his
wife, Susan. He's a
retired Air Force colonel.
I also had dinner
recently with Jay Stevens
and Dorothy Rasinski
and talked to Bob
Wilbee and Larry Way
on the phone. All are in
good health."
Seymour Grauer, MD '59,

Syosset, Y, General
Surgery. "I am director
of surgery at orth
Shore University Hospital in Syosset. I am
happily married, actively
practicing surgery, doing
some administrative
work and studying for a
master's in medical
management at ew
School University. I am
also traveling. Regards to
all!" tgrauer@liu.edu

36

1111111 Hpici11

Dorothy Rasinski Gregory,
MD '59, Long Beach, CA,

Internal Medicine. "I
served with the President's Commission on
Ethics in Medicine and
Biomedical and Behavioral Research and
currently am on the
VA's National Bioethics
Advisory Committee."
Eli Isaacs, MD '59,

West Bloomfield, MI,
Obstetrics/Gynecology.
"I am still working, but
not out of necessity."
Isaacs l23@aol.com 1950s

1960s
Barry Weinstein, MD '69,

(R-Amherst) Erie
County
Legislator,
15th District was
re-elected
in the
ovember
1999 elections. He ran
unopposed.

970s
Allen L. Carl, MD '79,

has been elected to the
American Orthopaedic
Association (AOA), an
international organization with a mission to
enhance the quality of
musculoskeletal health.
Membership in AOA is
achieved by those who
have made a significant
contribution to education, research and the
practice of orthopaedic
surgery. Carl is professor

Winter

2000

of surgery and pediatrics
in the Division of Orthopaedic
Surgery
at Albany
Medical
College.
He specializes in
the treatment of spinal
injuries and disorders in
children and adults.

1980s
Thomas Pullano, MD '8D,

writes: "Since completing my fellowship in
neonatal medicine at the
University of Colorado,
I have been working in
Dallas. I am now
medical director of the
eo natal Intensive Care
Unit at Presbyterian
Hospital Dallas and a
member of Magella
Medical Associates.

!ina]" article in the
Greenville Magazine.
Hollins is medical
director/administrator
for the Roger C. Peace
Rehabilitation Hospital,
which is part of the
Greenville Hospital System. He is the first
African American to
ever hold such a post in
the hospital system.
Hollins began practicing
in Greenville in 1991,
following completion of
his residency training in
Buffalo in Physical
Medicine and Rehabilitation. His wife, Suzette,
earned an advanced
graduate certificate in
information and library
sciences from UB in
1988. They are raising
their three daughters
in Greer, SC.

1990s

Tina Marie Gardner, MD '87,

Donato Borrillo,

writes from Stamford,
NY: "I am extremely
busy in a hospital-owned
outpatient practice. I
also teach reading to atrisk kids, serve as a Cub
Scout leader and am an
attending at a nursing
home. In my abundant
free time, I camp with
my husband, Joe, and
our two sons, Jake (9),
and Luke ( 4).

MS, MD '90, JD,

Dennis C. Hollins, MD '87,
PhD, was recently selected

for inclusion in the
annual "Best Doctors in
Greenville [South Caro-

writes: "! married Christine Wells of Cleveland,
OH, and have a ninemonth-old baby girl,
Jessica. After graduating
from UB medical school,
I went on to obtain my
law degree from Case
Western Reserve University and am licensed to
practice law in Ohio. In
addition, I completed an
aerospace medicine
residency at Wright State
University (board certified) and have a commercial multi-engine
instrument-rated pilot's
license. Currently, my

family lives in England,
where I practice as a
flight surgeon for the
352nd Air Force Special
Operations squadron at
RAF Mildenhall. Cheers!
William Palmer, MD '90,

and his wife, Stephanie,
announce the birth of
Jayson William Palmer
on September 6, 1999.
He joins his sisters,
Janee, 9, and Jilian, 7.
Palmer is currently in an
office-based physical
medicine and rehabilitation group practice,
Rehabilitation Associates
of Indiana, in Indianapolis, I
Krista M. ( Prigg) Kozacki,
MD '91 , writes: "Life is

wonderful in Florence,
S.C. We had our third
child, Emily Marie, on
July 9. She weighed 7
pounds. Her twin brothers Stefan and Jacob (age
6) think she is their little
princess. I more than
ever advocate breast
feeding to my patients
now! I am loving my
private practice more
and more every day. It
has been five years. I
also get to interact residents. Call if anyone gets
this way."

EDITOR'S

OTE:

Due to space limitations, several Classnotes
submissions were held
for the following issue
of Buffalo Physician.

�Your stock may pay more dividends
than you thought possible
You dabbled in the market long before it became a fad and your
hunches paid off. But now you need income, and your shares
are only producing low annual dividends. so how can you make
the most of your securities and still achieve your personal and
financial goals?
Give your stock to the University at Buffalo. With careful planning,
your gift may provide you with income fOr life, a charitable deduction and reduce or eliminate taxes. And fOr UB it can mean more
scholarships, research funds or the realization of your own
personal vision and goal fOr the University.
To learn how your gifts of stock can benefit you and the University
at Buffalo, please call the Office of Gift Planning at !716l 645-3312.

T~

University at Buffalo

':t=:::l The State University ofNew York

University at Buffalo • Office of Gift Planning • 103 Center for Tomorrow • Buffalo, New York 14260-7400 • 716-645-3312

�l•ffale Pllyslcla•
State IIIYirslty If lew Yerk at l1ffal1
M35 •ail St.
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l1ffale lew Yerk 1U1•·3113

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Buffo o NY
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We Get Rehab Results!
Our Superior ~M Improvement
Vs. National and Northeast-em
Regional Subacute Facillties

Hve Star Care

The McGuire Rehabilitation Centers achieve a 34%
GREATER FIM5 M increase vs. the national average for
all admissions.
• Stroke
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• Medically Complex
• Orthopedic
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• Joint Replacement
Eatll'lg
• Amputee

Our facilities were rated outstanding in the
community with five stars out of five, according to
the Inside Guide to America's Nursing Homes for
long-term care.

****

The McGuire
Team ofExperts
The McGuire Rehabilitation
Centers employ a team of
over 30 licensed Physical and
Occupational Therapists,
specially trained support
staff, and an on-staff
Physiatrist/ Gerontologist.
Together they ensure the
highest level of individualized
medical and restorative care.

Cost Effective!

=Inpatient Admissions

The McGuire Rehabilitation Centers'
average charge per case is more than 35%
WWER than other facilities in the nation,
according to statistics from The Wall Street
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I = Inpatient Discharge I = Outpatient Follow-Up

Our case mix is consistent with the Northeas t and national subacute region. Our
average s tatistics are: length of stay - 25 days; age - 78; admission FIM score 72.5; discharge F"JM score - 97.6 ; FIM change- 25 .1 points; length of stay
efficiency 1.40; onset time - 17; discharge disposition - 80% to community. Based
on 12 months ending March 31 , 1998.

The McGuire Rehabilitation Centers rely on the national
The results are in. The McGuire Rehabilitation Centers have
leading measurement tool for documenting patients'
the clear advantage over other regional facilities based on F!Ms"'
rehabilitative outcomes. This tool is !mown as FIMSM&lt;
improvement, discharge to home, and cost effectiveness.
lnstJument; Functional Independence Measure, developed
Our successful rehab program delivers results
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because of our superior staff, state-of-the-art equipment,
Functional Assessment Research. It's used
and specialized rehab facilities. Choose The
along with the Uniform Data System for
McGuire Rehabilitation Centers for five-star
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rehabilitation services.
to establish rehab outcomes that ~~"DU
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�</text>
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                    <text>�l1ffale P'ysiciaa
ASS OC I ATE V IC E PRESID ENT F OR
UNI V ERSITY SERV I C ES

Dr. Carole Smith Petro

Dear Alumni and Friends,

DIRE C T O R OF P U BLI C AT I O N S

Kathryn A. Sawner
E DI TO R

Stephanie A. Unger
I

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At this writing, we have
AR T DIRE C TOR/DESI GNE R

just returned from our Dean's Advisory Committee meeting in Las Vegas, ably hosted by

Alan]. Kegler

joan and Max Doubrava (Class of '59). Max also arranged a mini-reunion of the Class
of '59, and I am happy to report that class spirit is very much alive and well. Next month

ASSISTA NT DESIGNER

Lynda Donati

we will be in La jolla to meet with another group of alumni.
I have good news to report on the recruitment front: On May 1, 2000, Dr. john Yeh will
be joining us as chair of the Department of Obstetrics and Gynecology. Also, on August 1,

PROD UC TION COORDI N ATOR

Cynthia Todd- Flick

2000, Dr. Kenneth Blumenthal will be joining us as chair of the Department ofBiochemistry

STATE UN IVER S ITY O F

(see pages 26-28 for details). Our next major challenge will be to shore up the Department

YORK AT B U FFALO S C HOOL

of Surgery, an essential medical school department that urgently needs some help.
By now many of you have probably heard of the federal audit under

EW

OF MEDICINE AND
BIOMEDI C A L SCIEN C ES

Dr. fohn Wright, Dean

way in Buffalo, involving the medical school and a number of its affiliated
hospitals. This type of audit has been experienced by almost one-third of
the medical schools in the country and has caused considerable concern at
each location. In our very distributed system, it has been very difficult to
monitor the practice plans as closely as would be ideal. But the bright side
is that, once this is all over, we might achieve a more consolidated system.
Similar audits are going on at Stony Brook and Downstate, but we don't
have too many details yet as to where our own particular audit is headed. I just wanted to
let you know firsthand in case you were to hear about it secondhand.
Our medical students are putting the finishing touches on a "Professionalism Program," the centerpiece of which will be a student-generated code of conduct and student
involvement in implementation. This has been a much hoped-for student-initiative for
some time; thankfully-particularly in this increasingly difficult environment-our
students have taken on the challenge. If you care to monitor progress, you can visit the
students' website at http://www.smbs.buffalo.edu/CPCx.html. I am certain they would
welcome your comments and input. We will be instituting several other facets of this
important program at the resident and faculty levels, so stay tuned. We also plan to provide
opportunities for input at Spring Clinical Day events.
The Mini-Med School, directed by Harry Sultz and Alan Reynard, is a continuing
success, and ours is the first in the nation to have a full-fledged "Mini-Med School Alumni
Association." More than 2,000 participants have attended the program since its inception

EDI TO RIAL BOARD

Dr. Bertram Partin, Chair
Dr. Martin Brecher
Dr. Harold Brody
Dr. Linda]. Corder
Dr. Alan]. Drinnan
Dr. ]ames Kanski
Dr. Elizabeth Olmsted
Dr. Stephen Spaulding
Dr. Bradley T . Truax
Ms.]ennifer Wiler
Dr. Franklin Zeplowitz
TEA C HIN G HOSPITALS

Erie County Medical Center
Roswell Park Cancer Institute
Veterans Affa irs Western
N ew York Healthcare System
K ALEIDA H EAL TH:

The Buffalo General Hospital
Til e Children 's Hospital of Buffalo
Millard Fillmore Gates Hospital
Millard Fillmore Suburban
Hospital
C ATHOLIC H EALT H SYSTEM:

Mercy Health System
Sisters of Charity Hospital
Niagara Falls Memorial
M edical Center

in 1997, and Harry has received recognition for it from the community on a number of
instances. just recently, he was recognized as a "Health Care Hero" by Business First,

@TIE STITIINIYEISITJ I I lEI Ylll U lllllLD

Western New York's business newspaper. In collaboration with the UB Law School, a
program based upon a series of medical-legal vignettes and specifically targeted to the legal
profession was launched on March 2, 2000.
There is a lot going on here- some of it admittedly bordering on the unpleasant, but
much more of it progressive and frankly uplifting.
~

~C/~

~ jn~:"N

R.

WRIGHT ,

Buffalo Physician is p ublished
quarterly by the S tate University of
New York at Buffalo School of
Medicine and Biomedical Sciences
and the Office of Publications. It is
sent, free of charge, to alum ni,
facu lty, students, residen ts, and
frie nds. The staff reserves the right
to edit all copy and submissions
accepted for publica tion.

MD

Dean, School of Medicine and Biomedical Sciences

T...=.:.. University at Buffalo

-:a=:s The State University ofNt'w York

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34 ,

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HEALTH SCIENCES
AUG 1 4 2000

Features

2

Rehabbing from Within
A doctor's tale of trauma,
and the long road back
BY jONATHAN BEAN ,

8
14

MD

' 89

Little Ears, Big Infections
Vaccine developed for treating
otitis media and COPD
BY

S. A.

UNGER

In 1989, soon after beginning his internship, Jonathan Bean, MD, was severely injured when hit by acar
while crllSsing the street. Beginning on page 2, Bean, aphysiatrist, tells of his journey back to health.

Brain Drain
New clues to how alcohol
affects the aging brain
BY

LOIS BAKER

ABOUT THE COVER

RODS

A~D

jONATHAN BEAN HOLDS THE

SCREWS IMPLANTED IN HIS PELVIS AND
LEG AFTER THE ACCIDENT.

CovER

12 Michael White,
Class of 2000,
returns to
his adopted
homeland of
Brazil to
complete an
infectious
disease
rotation

18 Program to
help students
gain entrance to
medical school

20 New institute
established

21 Grant supports
development of
two new centers

26 Kenneth
Blumenthal
named chair of
Biochemistry

28 John Yeh, MD,
named chair of
Obstetrics and
Gynecology

30 A salute to the
Class of 1945

31James Platt
White Society
Annual Listing

PHOTO

36 News from
your classmates
and other UB
alumni

39 Stuart Collins
and Peter julian
remembered

BY j o s H

LEVINE

41 Deborah,
Christopher
and Adam
White
Memorial Fund
established

�Photos by Josh Levine

•

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I

1111111 ••r•lcl••

��IKETHEINCANDESCENTBARRELOF ASHOTGUN, the two headlights bore down. There was no turning back. I took two running
steps and dove for the sidewalk. In that instant, I recalled afootball game from my youth. After intercepting apass,
I was able to dive over the goal line before the tacklers stopped my momentum. I had the elated sense that I would
triumph again. Apiercing crack and the sudden sensation of being forcefully twisted through the air jolted such
thoughts away. As I carne to rest, 10 yards down the sidewalk, the smell of concrete dust permeated my nostrils. I
instinctively attempted to stand, but it became evident I could not control my legs. Blood and torn flesh covered my
right thigh. As I untwisted to lie back down, an exquisite raw pain enveloped my pelvis. I cried out for help. No one
answered. I cried out again, but in response heard only the receding sound of screeching wheels in the distance.
Eventually, assistance arrived. In the ambulance, with the siren blaring, I considered what would occur
next. I could see the paramedic's watch on his wrist. Ironically, I would arrive at work on time.

Survey of the Damage
Twelve hours later, in a clouded state, I awoke in the
surgical intensive care unit. There was a lattice of
metal rods screwed into my pelvis and a full-length
cast encasing my right leg. Surgery had been lengthy.
My pelvis had been fractured in two places and my leg
in three. More surgery was scheduled for the coming
days. The nurse pointed to a button near my hand,
explaining that I could control the morphine dose
myself. She suggested that I get
some rest. Pain ran up and down
my body. I gave a press and fell
to sleep.
When I next awoke, I was in a
private room. Dr. M., one of the

•

l 1 1f a l e Hysiei11

Spr in g

2 000

most respected members of the medical staff, smiled
down at me. He explained that I was under his
group's care, that my surgery had been 36 hours earlier
and that my anesthesia was still wearing off. With
some hesitation, he asked, "You're going into physical
medicine and rehabilitation aren't you?"
"Yeah," I said, "at Tufts."
He shook his head in disbelief and said, "Well, I
guess you're going to learn rehab from the inside."
He pointed to the morphine pump. "These PCA
pumps are new. I'm not so sure they' re a good
thing." Turning to leave, he patted my cast and said,
"Get some more rest. You'll need it."
I looked around the room. A half-eaten sandwich
and my sister's coat were lying on the chair
at the foot of my bed. Still unable to stay
awake, I closed my eyes. Occasionally, I awakened to see the faces of my concerned family
or a nurse changing my IV, but each time I
sank back into oblivion, my sleep deepening.
Finally, I fell into a sleep that was
profound; blissful, even. But in the distance
I could hear someone calling my name. His
voice became louder and increasingly
urgent. I was being yanked from the comfort
of my dreams. I felt him slapping my arm, and
then a sharp stab at my wrist. Opening my
eyes, I saw Rick, one of my fellow
interns, drawing a blood gas. I had never
seen him so frightened. He clamped an oxygen mask on my face and told me I was
being transferred to the Intensive Care Unit.
Later that day, with the overwhelming sensation that
I was breathing through a straw, I underwent the
obligatory workup. I had suffered a fat embolism.

�Long Road Back
Pain Mismanagement
After an extensive debate, the physicians decided not to
intubate me. Though the respiratory distress was a consequence of emboli released from the fractured bone
marrow, they still felt that my use of the morphine
pump was to blame. Today, I know better; nevertheless,
for the rest of my hospitalization I was labeled as
someone for whom narcotics should be minimized.
Over the course of the next month, I learned firsthand
many of the pain-management principles that would
later be a part of my physiatry training. For example, I
learned that pain medications with a half-life of four
hours should not be prescribed every six, and that it
takes 15 minutes for a nurse to deliver a prn
medication and an additional half hour before
it takes effect. I learned about the difference
between bone pain and neuropathic pain, and
that narcotics do little to quell the latter. Most
notably, for the next nine weeks I came to
know the unrelenting tedium, frustration and
helplessness of pain mismanaged.
An important topic in every physical
medicine and rehabilitation text is the medical
consequences of bed rest and immobility. Bed
rest affects every organ system. As a consultant, I am familiar with the facts: Hemoglobin
and blood volume decrease; muscle strength
weakens l to 3 percent per day; and heart rate
elevates one beat for every two days in bed.
Conditions like constipation, postural
hypotension and contracture often occur. I experienced these and other complications.
Upon discharge from the acute-care hospital, my
resting heart rate had elevated from 60 to 85, and my
weight had fallen from 155 to lOS pounds. Once I was
allowed to bear weight in my eighth week of hospitalization, the postural hypotension was so severe that it
took 10 days of tilt-table training before I could stand
without passing out. Coupled with the narcotics, the
constipation became so bad that enemas and manual
disimpaction were commonplace.

B

Devoted Friendship, the Best Medicine
esides all of these issues, lying in bed for nine
weeks was both boring and depressing. My
concentration was clouded, so reading was very
difficult. I became far too acquainted with the
emptiness of daytime television. Evenings were
the best times because my girlfriend, Melissa, would
visit. She brought a VCR and we watched rented movies
until visiting hours ended. Nights were very hard.

Minus daytime distractions, my pain escalated, and the
night nurses were always slower about delivering
medications. Lying in the darkness, only partially able
to turn side to side, I listened to the sounds of the
hospital, wondering ifl would ever walk again.
The worst times, however, were the mornings. In
my dreams I was always healthy-swimming, climbing
mountains or just running with reckless abandon.
Waking to the cold truth of the hospital room and my
broken body was like being hit by a car all over again.
Importantly, for three straight weeks, I was distracted by the sound of snoring. Reclined in the chair
at my bedside was Dave Blaustein, a fellow intern and

one of my best friends from medical school. After
completing his night-float shift, he visited me rather
than going home to sleep. Unshaven, with his rumpled
lab coat draped askew, he often
had a fresh banana peel lying on his
-Jonathan Bean today
chest. (My family kept the bedside
stocked with fresh fruit and juice.)
with his wife, Melissa, and long·
Upon waking, I'd nudge Dave with
time friend and DB alumus
my long-handled reacher, and for
the next 20 minutes we'd talk like
David Blaustein, MD '89, right.
we always had, joking about the
doctors who took themselves too
seriously and cursing the nurses who had given us a
hard time. We also talked about sports and politics
and shared stories of past escapades. He always left
time to hear how I was doing and to validate my
frustrations. As much as anything else, he helped me
to feel as if things were normal, even if circumstances were not. He taught me about healingthat there are times when devoted friendship is the
strongest medicine of all.

Spring

2000

l1ffala Pbysic i u

5

�A

The Group of Four

fter nine weeks of lying in bed fulfilling the typical
passive role of a patient in an acute-care hospital, I was
transferred to Magee Rehabilitation Hospital. Inpatient rehabilitation requires a patient to function as
independently as possible. Patients often wear street
clothes, signifying a sense of normal life. For most
patients, however, it feels more like boot camp.
Given my anxious and disoriented look, it was clear
to all those around me that I was a new admission.
After having gone through the multiple initial evaluations by nursing, physiatry and social work, I was told
to make my way down to the cafeteria for dinner. Now
that the external fixeter had been removed from my
pelvis, I was able to sit upright and independently
propel my loaner wheelchair. Staff helped me when
asked, but otherwise tended to those with greater needs.
The other patients observed me, though no one
initiated conversation and most avoided eye contact.
This was particularly true for a group of four youngadult paraplegics of diverse racial background who
wore fingerless black leather gloves and were unified by
their reliance on lightweight custom wheelchairs. They
joked together, darting glances in my direction during
pauses in their conversation.
Over the next few days, this group of four seemed to
follow me around. They often hovered closely, be it in
the cafeteria or the therapy gyms.
Despite this progress, it took
Like a group of adolescent skateboarders, they practiced pulling
four more surgeries and five more years
wheelies and jumping curbs.
of rehabilitation before I considered
They observed with knowing
curiosity as I strengthened my
myself substantially recovered.
atrophied arms and shoulders.
Though nearby, they never approached or outwardly
addressed the fear I felt inside.
Then on the fourth day, my physical therapist
announced that it was time for me to use the stationary
bike. Despite the fractures and nerve injury, the healthcare team agreed that with the return of strength, I
would walk again . Initially I was concerned about pain
or falling, but I felt more confident with each minute
of riding. As my legs became more comfortable, I
increased the pace. Closing my eyes, I soaked in the
long-missed exhilaration of exercise.
Eventually, I became aware that the group of four
was parked around me. They had mystified looks on
their faces. One spoke, "So, you can use your legs."
"Yes," I said with a selfish pride, ''I'll start walking
with crutches tomorrow."
"Wow, that will be great for you," he said, with a
mixture of generosity and sadness.

6

l affal1 Hysicin

Spring

2000

I sensed the awkwardness of the moment and
struggled with a response. He spared me the discomfort by asking about my injuries. He shared that he had
suffered a lower-cervical spinal cord injury as an
interscholastic wrestler. The others had suffered
injuries from a motor vehicle accident, a gunshot
wound and a diving accident.
They wished me the best and then slowly wheeled
away in separate directions. Framed by wheelchairs,
with their narrow legs folded neatly beneath the seats,
they suddenly looked young and vulnerable. At that
moment, I realized that I had been undergoing a rite
of passage, an initiation into the world of spinal
cord injury (SCI). Once it was clear that my spinal
cord was spared, the process suddenly ended. I
became a spectator, not an insider.
As a physiatrist, my training has taught me that in
SCI almost all body systems are altered. The adjustments to the many social and emotional changes are
even more challenging. It can be a very difficult and
lonely transition. Throughout the rest of my hospitalization, I rarely saw any of those four again, though
they always greeted me with kindness when I did.

I

Imaginary Finish Line

n late January 1990, after three months ofhospitalization, I was discharged to home. In March, I
returned to work. Despite this progress, it took four
more surgeries and five more years of rehabilitation
before I considered myself substantially recovered.
Exercise and patience were my daily medications.
Most of the feeling has returned in my leg, and
every once in a while I go for a long run. At last year's
Spring Clinical Day and Reunion Weekend-which
included a reunion for the Class of 1989-I returned
to one of my favorite places in Buffalo, Delaware
Park. Running around the familiar path, my thoughts
sifted through the last 10 years. With my asymmetric
gait, I sprinted the last half-mile as if it were the end of
an important race. As I passed the imaginary finish
line, no one cheered or celebrated. The victory was a
private one. My experiences did not dramatically
change my goals, nor did they lead to some sort of
religious epiphany. They have been woven into the
fabric of my life. Ultimately, illness is a solitary experience of adjustments that are only partially shared
with others. In recognition, as a physiatrist, I lend a
hand, assisting my patients to feel intact again. 4D

�Spring

2000

luffal1 Hysiciaa

7

�BY

s.

A.

UNGER

PHOTO

BY

K.C.

KRATT

Little

Ears,

Big
Iiifections

vaccines
to prevent
ear and
respiratory
tract
infections

lF YOU WANT TO GET the attention of
parents with young children, just tell them
that scientists are making significant strides
toward developing a vaccine to prevent
recurrent ear infections.
A leader in this endeavor is Timothy F.
Murphy, MD, a University at Buffalo professor of medicine and microbiology whose
research is currently funded by a five-year,
$1 million grant from the National Institutes
of Health (NIH). The vaccine Murphy is
developing targets a bacterium called
non typeable Haemophilus influenzae (NTHI),
which not only is the second most common
cause of ear infections (otitis media) in children, but also is a leading cause of recurrent
infections in patients with chronic obstructive
pulmonary disease, or CO PD. A vaccine against
THI is especially promising because it would
be effective in both populations of patients.

8

l•ffale Plysicial

S p ri n g

2 000

��I

LITTLE

EARS,

BIG

INFECTIONS

EDIA and COPD are enormous national health problems in terms of human suffering and cost,"
rphy, whose work in this area has been continuously funded by the NIH since 1983. "About 80
of children have a least one episode of otitis media by age three, and it is the most common reason

£ rvisi s to pediatricians. Recurrent otitis media is painful and because it impairs hearing, it is associated with
d lays speech and language development, as well as with learning problems in children as they reach school
PD, which includes chronic bronchitis and emphysema, is the fourth leading cause of death in the
States, with infections being the most common singie identifiable cause of these deaths."
der for a vaccine to be effective against recurrent ear
.._........-~,ions, it must work within the first months of a child's life,
according to Murphy. This is because if a child's throat becomes
colonized with NTHI during his first year of life-even in the
absence of an ear infection- he may then be prone to ear infections throughout childhood. "Some vaccines do not induce an
immune response in children under age two. It will be critical to
develop a vaccine for ear infections that is effective in infancy
because it will be important to immunize early to prevent
recurrent infections, which are the real problem," he explains.
To that end, Murphy's work focuses on two proteins on the outer membrane surface ofNTHI-P2 and P6-each of which has the
appealing feature of being able to generate antibodies in infants.
"P2 makes up 50 percent of the protein content of the outer
membrane and is an immunodominant protein, which means it induces the human host to make antibodies to it," says Murphy. "And
what's interesting about it is that if we look at its amino acid sequence among strains, it's different, particularly the parts of
it called 'loops' that stick out."
It turns out that these heterogeneous loops of P2 were
key to answering a crucial
question driving vaccine
research in this area: Why do
children with normal immune systems get recurrent
ear infections? Itwas Murphy,
working in collaboration
with Howard Fadden, MD,
at Kaleida Health's Children's Hospital ofBuffalo, who
played a leading role in answering this question. "We now have reason to believe that it's
because these children with otherwise healthy immune systems
are making strain-specific antibodies to these so-called antigenically heterogeneous loops on P2, which leaves them susceptible to
reinfection with the heterologous strains," Murphy explains.
The fact that the strains are varied "outlines the challenge we
face in trying to make a vaccine to prevent these recurrent infec-

..
..

..

10

laffal1 Pbysiciae

Sp rin g

2 00 0

tions," he says. "So, the approach we've taken is to try and identify
the proteins on the surface of the organism that are the same from
strain to strain, or what we call 'antigenically conserved."' In his
current study, Murphy has fully explored this approach and he
and his team have successfully identified conserved loops on the
P2 molecule. "In fact, we can now generate antibodies to these
loops, and they kill multiple strains of the organism," he reports.
The other protein Murphy is focusing on in tandem with P2 is
P6. Since discovering this protein 15 years ago, Murphy has learned
much about it, including the fact that
Astrategy to present the
it is antigenically conserved; in other
words, it is identical in amino acid
P&amp; molecule for destruction,
sequence from strain to strain. In
with the goal being to produce addition, he has made several other
discoveries that suggest that P6 would
a"lethal mutation" in the
make a good vaccine antigen. First, he
targeted bacterium.
determined that the protein is on the
surface of the organism, so antibodies
can easily bind to it. Second, studies he conducted on human serum-and confirmed by
animal studies in other labs-indicate that
antibodies to P6 will protect the host by killing
the organism. Finally, he has demonstrated
that P6 is critical to the viability of the
organism; it can't live without it.
This latter feature is noteworthy, according to Murphy, because bacteria, like all
microbes, can shut off production of surface
antigens if they are targeted for destruction,
a trick scientists term "phase variation."
"P6 is critical to the organism, so it can't shut it off," he says.
"In fact we've actually attempted to make a mutant of NTHI
that lacks P6 and have been unable to. The organism won't
survive without it; it's a lethal mutation."
The downside ofP6, however, is that it makes up only 5 percent
of the surface of the protein, so in effect it is "hidden" by the
organism. "What remains to be determined, therefore, is whether
there's enough of a target there for the vaccine to work," Murphy
explains. An answer to this question will begin to unfold in the years
ahead, as UB has signed a licensing agreement with a pharma-

�MURPHY IS ACTIVELY EXPLORING ANOTHER INTRIGUING POSSIBILITY: DEVELOPING
A VACCINE THAT CONTAINS MULTIPLE ANTIGENS HOMING IN ON MULTIPLE TARGETS.
ceu tical company, Wyeth-Led erie, in Rochester, New York, which is
currently testing in humans a P6 vaccine based on Murphy's research.
"What my lab has done is identify and characterize vaccine
antigens and perform initial studies supporting the potential
viability of the vaccine; it's up to the pharmaceutical companies to
produce large amounts of the vaccine antigen for testing, which is
now happening," says Murphy, who holds multiple patents on the
P6 molecule pertaining to its gene and protein sequences and
purification and diagnostic methods.

C

urrently, Murphy is dedicating his research efforts to continuing to learn as much as possible about the P6 molecule
and the human response to it. "In particular, I want to know
what parts of the molecule they [vaccinated individuals] are
making antibodies to. Recently, we've done a lot of work on
the antigenic structure of the P6 molecule, looking at how this
protein is arranged in the outer membrane. Now we want to
identify the specific parts of the molecule that are protective."

Murphy is also actively exploring another intriguing possibility:
developing a vaccine that contains multiple antigens homing in on
multiple targets. Given the fact that P2 is so antigenically appealing,
he posits, "Why not splice out its immunodominant loop-loop
five, which is very heterogeneous from strain to strain, and people
love to make antibodies to it-and put in there an important part
ofP6? In other words, why not make P2 a vaccine-delivery system?"
By developing a P2-P6 hybrid molecule, he says, "We'd be taking advantage of the immunodominant observation-that humans love to make antibodies to P2. But then we'd manipulate the
molecule by putting in the P6 we want the host to make antibodies
to. In essence, we'd be using the 'juicy' part ofP2
to rev up the immune system to kill p 6, which
SanjaySethi,MD, collaborates

will have a bactericidal effect. So we wouldn't be
focusing exclusively
on either P2 or
P6. We'd be taking
both routes." CD

S p ring

2000

with Murphy on clinical studies.

l11fal• Hysiciu

11

�S

B
MI

W

C

H

T

U

D

E

N

T

COLUMN

Brazil Redox

v
HAEL

I

T

E

Mi chael White , MD ' 00 , Returns to Hi s Adopted Homeland

ERY QUICKLY

l

REALIZED

that my infectious disease
rotation in Brazil was
going to be a novel experience when, on my very
first day at the
Hospital Ferreira
Machada, our group
of 20 medical students was led by our
professor into a
room where a fouryear-old girl lay
suffering on a cot.

I

..
..
c

12

l•ffal• nysicia•

She was feverish and
very jaundiced, and her
abdomen was distended. As the doctor approached the child to
perform an exam, she
cried out with anticipatory pain. Very calmly
and gently, the physician
examined the wary child.
It was obvious that every
nerve ending was hypersensitive and that each
touch sent bolts of pain
through her tiny body.
To give us further
insight, the parents recounted the story of their
child's illness. Approximately 10 days earlier, she
had complained of abdominal discomfort and
fatigue, which had progressed to nausea and
vomiting. She then refused to eat, began to look
yellowish and developed a fever.
The physician took her parents aside to describe
the gravity of the situation to them, explaining that
their child's liver was not working well, which was why
her skin tone was yellow and her abdomen was

Spring

2 0 00

enlarged. Of even greater concern, he explained, was
the fact that the minerals in her blood were not
being maintained at appropriate levels. The child, he
added, was also at a high risk of bleeding because
her platelets were low.
Unfortunately, the parents refused to have her
placed in the ICU because their visitation time would
be markedly reduced.
During this exchange, we also learned that the
family was very poor and unable to pay to have a
sample of the girl's blood sent to Rio de Janeiro for
etiologic determination of hepatitis. As a result, the
students decided to pay for the test themselves.
The next morning, we learned that the child had died.
A week later the lab report arrived, confirming the
infectious agent as hepatitis A.
This shocking initiation into the Brazilian healthcare system was distressing, yet educational and very
beneficial. Compared to the health-care system in the
United States, the Brazilian system appears to be much
simpler and more direct. As I soon discovered, however, it has an acute yet broad pathology of its own:
Despite the fact that many of the country's health-care
facilities possess all the amenities of American facilities, the Brazilian public is far too poor to access them.
I also learned that in Brazil treatment regimens are
frequently engendered without a definitive, formal
diagnosis; for example, the child with hepatitis was
treated with corticosteroids based solely on history
and prior to etiologic delineation of her illness. Furthermore, I was very surprised to discover that clinical
impression and physical diagnosis play the primary
role in diagnosis and treatment in Brazil, whereas in
the United States, a physician's interpretation is used
as a startingpointand is characteristically implemented
only after diverse and diagnostic laboratory tests are
performed. This approach to diagnosis and treatment,
although discussed frequently during medical school,
had previously struck me as fraught with error and
unreliable for practical application.
However, my Brazilian experience taught me the
merit of a methodical approach to the ill patient that

�ALTHOUGH MY FOREIGN LANGUAGE STUDIES CONSISTED ONLY OF A SEMESTER OF
EIGHTH-GRADE LATIN,

l

WAS A BOLD 18-YEAR-OLD WHO JUMPED AT THE CHANCE FOR SUCH

AN ADVENTURE. UNDEltSTANI)ABtY, MY PAREN'f-5 WERE ANXIOUS ABOUT THEIR SON MOVING
MORE THAN 5,000 MILES AWAY, BUT THEY WERE VERY SUPPORTIVE.
includes a thorough and well-planned history and
physical examination, as well as a fundamental understanding of disease processes and a faith in one's own
medical judgment. In contrast, when working in a
health-care system where frequent laboratory studies
are the exception, fundamental understanding and
application of basic medicine is the rule.

In the following years, I often dreamed of returning
to Brazil, and once I entered medical school, the idea of
setting up a rotation there intrigued me. Not only would
such an experience allow me to revisit that beautiful
country, it would give me an opportunity to practice the
new love of my life, medicine.

Just Another Brazilian Medical Student

A Homecoming of Sorts

1

hese experiences and powerful impressions were a
stimulating introduction to the month-long
infectious disease rotation I undertook late in the
summer of 1999 as part of my fourth year of medical
school. While the rotation was the source of many
new and exciting insights, my visit to Brazil itself
was not a novel experience; in fact, it was a homecoming of sorts, a sequel to a year-long visit I made
to the country in 1990 while a senior at Portville
Central School near Olean, New York.
While in high school I had met a Brazilian exchange
student, and we quickly became friends. As his visit
drew to a close, he invited me to return to Brazil with
him and live with his family. Although my foreignlanguage studies consisted only of a semester of eighthgrade Latin, I was a bold 18-year-old who jumped at
the chance for such an adventure. Understandably, my
parents were anxious about their son moving more
than 5,000 miles away, but they were very supportive.
My first few months in Brazil were among the most
challenging of my life. I battled through various illnesses, a completely new diet, an inability to speak the
language, and initiation into a very different culture. I
attended a local public school, met more Brazilians,
joined a basketball league and found a teacher who
was willing to tutor me in Portuguese.
Slowly, I learned. Through charades and common
sense, I began to acquire a vocabulary and an understanding of the culture. My peers taught me how to
speak basic Portuguese, including the slang terms,
and my teacher taught me formal Portuguese, as
well as how to read and write the language.
By the time I returned to the United States in 1991,
I was very proud of the fact that I could be mistaken for a Brazilian teenager due to my fluency
in Portuguese.

I

n the fall of 1998, I began to
contact friends in Brazil.to he.lp
me arrange a rotatiOn 1n
Campos, a city of 500,000 people located three hours north of
Rio de Janeiro. Its economy is
dependent upon sugarcane
plantations and the factories that
produce sugar granules, drinking alcohol and alcohol for use
as fuel in cars. As residents of a
plantation town, many Campistas are poor and uneducated;
few study beyond high school.
With the help of my Brazilian
friends, I obtained contacts at a private hospital
(Hospital Geral Doctor Beda) and a large public hospital (Hospital Ferreira Machada). Through these
contacts, arrangements were made for my rotation.
Prior to my departure, I spoke with Dr. Nelia
Artiles Freitas, head of infectious diseases at Hospital
Ferreira Machada. We outlined my responsibilities,
agreeing that, throughout my stay, I would be treated
as one of the Brazilian students from the local medical
school (faculdade de medicina de Campos) studying
infectious diseases. As a result, immediately upon my
arrival in early August, I assumed the same hospital
schedule as the other students; I also researched
diseases, attended classes and took exams.
Over the course of my rotation, I saw numerous
infectious disease cases at various stages, including but
not limited to lepromatous leprosy, leptospirosis,
herpes encephalitis, tetanus with sorriso sardonicus,
pulmonary varicella, ascaris, gonorrheal meningitis,
disseminated TB, various fungal infections, HIV and

I

CONT I NUED

ON

P AGE

While in Brazil, White
was hosted by the
Fusco family. Pictured
above, is 11·year·old
Gregory Arenari
Fusco Soares,
learning how to use a
stethoscope by
listening to his
ownhean.

4 0

S pri ng

2000

luffale Pbpician

13

�14

�BY

LOIS

BAKER

Alcohol' effect on the aging brain
PHOTO

BY

K.

KR

TT

Does drinking really kill brain cells? If not, what oes happen, and h w?
Is the damage permanent? oes chronic alcohol abuse in late adulthood
increase the deficits caused by aging? For 16 years Roberta J. Pentney,
PhD, U professor of anatomy and cell biology, has pondered these basic
questions concerning chronic alcohol abuse and brain function.

Spri11g

2000

Blff311 Pbysiciu

15

�C

ELL MORPHOMETRY-the quantitative study of the form and structure of cells-is Pentney's field, and

her painstaking work with neurons in the cerebellum, the control center for movement, coordination

and equilibrium, has yielded striking and unexpected answers to difficult questions. For example:

Q: Does alcohol kill brain cells in adults?
Not in the cerebellum.

Q: What does happen?
Alcohol damages dendrites, reducing
message traffic between neurons.

Q: Is the damage permanent?
No, it's mostly reversible; however,
neuronal structure is changed in
the process.

Q: Does alcohol abuse make people age faster?
No. Age and alcohol appear to act on
neurons in different ways.

Why is this information important?
"It shows that we are moving toward
finding out how alcoholism damages the
brain , information that eventually could
lead to treatments or prevention of the
destructive effects of alcohol on brain
function in humans," Pentney says.
"For a long time, people were looking
at cell loss as the real measure of alcohol's
effects," she says. "What we've seen through
this research is that you don't have to lose
entire neurons to disrupt brain function. All you need is damage, and we have
developed a model for that kind of change
with alcohol.
"Damage to the brain caused by alcohol, we now think, is probably similar to
the way alcohol affects the liver: There is
dam age and repair. Alcohol acts on a

16

1111111 Pbpiciu

Sp r ing

2000

number of molecules that interact with each other. Just getting
to the point where we can look
at a specific part of a cell that is
involved is a big step forward. "
Identifying that particular
part of the neuron affected by
alcohol-a structure called the
smooth endoplasmic reticulum, or SER-has been accomplished with the aid of $1.4
million in grants from the
National Institute on Alcohol
Abuse and Alcoholism , including a current grant for
$645,000. Pentney's research
and that of her coinvestigator,
Cynthia A. Dlugos, PhD, UB
research scientist in anatomy
and cell biology, concentrates
on a condition called lateonset alcoholism.
"Everybody else has been
interested in dealing with alcoholism in the early
also bears a striking resemblance
stages of life," PenThe Purkinje neuron with full
to a tree, and in scientific partney says. ''I'm looklance its branches are called, acing at a span during dendritic arbor; a magnification
cordingly, the dendritic arbor.
maturity that applies
of (A) terminal segments and
Pentney and colleagues are
to human alcoholism, and at the com(B) loss of a terminal segment.
on intimate terms with these
arbors . They have examined
bined conditions of
thousands of light-microscope images
aging and alcoholism."
The object of her attention is a specific and electron micrographs-photos
type of brain cell in the cerebellum called a taken with an electron microscopePurkinje neuron. Pentney considers this looking for changes in shape and signs
neuron one of the most spectacular in the of thinning, and counting dendritic
brain. Under the microscope it resembles a branches and segments and measuring
vast riverine system with branching den- their length s. They have al so determined
drites forming the tributaries. The neuron the total number of synapses, the sites

�on the ends of branches that receive
nerve impulses.
Conducting this kind of research with
humans is clearly out of the question.
Pentney has been working with Fisher 344
rats, whose 22- to 27-month life span has
been fully studied and documented. To
mimic the neuronal responses of a middleaged human, she begins her interventions
with rats that are 11 to 12 months old.
In all investigations, Pentney and colleagues used long-term study periods,
usually 40 to 48 weeks, to mimic human
chronic alcohol intake. One group of
middle-aged rats received a liquid diet
containing ethanol. A control group of the
same age received the same liquid diet with
the same number of calories but without the
alcohol, and a second age-matched control
group received a standard rat-chow-andwater diet. The researchers examined and
compared the structure of Purkinje neuron
dendritic arbors from aU groups.
Over the years a picture emerged of the

of synapses. "This was a hopeful note,"
Pentney says. "Every change we saw was a
reversible phenomenon. The brain was
repairing itself after alcohol damage."
That was good news, but it came with
a cautionary note: While the number of
terminal segments and synapses had returned to normal, the researchers knew
from experience that their placement on
the dendritic arbor most likely would be
different than before treatment. Pentney's results supported the hypothesis
that Purkinje neurons were changed
after recovery.
"The implications here are clear," she
says. "The branching pattern in Purkinje
neurons after recovery is not identical to
that before recovery; you don't end up with
the same arrangement. There is a fair
amount of recovery, but the neurons may
not function in the same way. A different
branching pattern would result in a change
in message transmission, which would
change the way that part of the brain works.

channels, they discovered that the
channels were dilated in alcohol-fed rats.
This change in neurons, Pentney says, is
usually associated with the entry of excess
calcium into the cell. o dilation was
found in the control animals.
"Calcium turns things on in cells,"
Pentney says. "Too much calcium stimulates too much activity and can kill cells.
The SER sequesters calcium within the
cell until it is needed. We're thinking that
in the case of the Purkinje neuron, localized dilation of the SER is causing the loss
of dendritic terminal segments but is not
killing the whole cell."
Knowing that alcohol-fed rats recouped
their synapses after recovery, the researchers expected to see the SER function return
to normal also, but it did not. At some point
during alcohol recovery, aging began to have
its own effect, independently producing
dilation of the SER membrane. Finding out
when in the life cycle this phenomenon
occurs is important, Pentney says, because

"THE BRANCHING PATTERN IN PURKINJE NEURONS AFTER RECOVERY IS NOT IDE TICAL TO THAT BEFORE RECOVERY;
YOU DON'T END UP WITH THE SAME ARRANGEMENT."
effects of alcohol on these neurons. The
researchers observed a significant thinning
of arbors in alcohol-fed rats, compared to
controls. Next, they showed that this thinning resulted from the loss of terminal
segments-those at the periphery of the
arbors- at the point where they branch
from the parent shaft.
Because synapses are located on terminal segments, losing some of these segments
would result in fewer synapses and, therefore, a reduction in message traffic between
neurons in this part of the brain. According
to Pentney, these findings may relate to
some of the abnormal movements often
seen in alcoholics, such as unsteady gait,
tremors and Jack of coordination.
Turning to examining the damage to
Purkinje neurons after recovery from alcohol treatment, the researchers were in for a
surprise: Expecting to see thin arbors and a
Joss of synapses, they found instead lush
dendritic arbors and the normal number

"We

now had a model that might
apply to what is happening in
recovering alcoholics," she says.
"Most of their motor functioning
returns to normal, but some does not."
Having determined that parts ofPurkinje
neurons disappeared in alcohol-fed rats, the
questions now to be answered were, Why and
how are these segments being eliminated?
Pentney and colleagues considered the
possibility that the segments had
atrophied from lack of stimulation from
interconnecting nerve cells in the cerebellum, which may have been killed by
alcohol. That turned out not to be the case.
They found instead a completely different mechanism at work. They were able
to show that the cellular structure responsible for regulating the flow of
calcium within the neuron- the smooth
endoplasmic reticulum- was being
disrupted in the alcohol-fed rats. Measuring the diameter of these calcium

it will help define how alcohol and aging
impair brain function-information that is
relevant to recovering human alcoholics.
"This information tells us that alcohol
and aging may act on the brain independently," she says. "It also indicates that
these two conditions are disrupting control of calcium in different ways, only one
of which leads to deletion of dendritic
segments and, by extension, to impairments of normal brain function."
Next, the researchers hope to determine exactly what part of the SER
membrane is being disrupted.
"We are moving toward a mechanism
of alcohol's effect on the aging brain,"
Pentney says. "This research allows us to
look at particular components of neurons
and understand how their function is
related to structure. Maybe if something
is missing, we can supply it. Maybe all we
need is a single change to prevent these
alcohol-induced impairments."
&lt;D

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SAWYER

Support for economically and academically disadvantaged students
HE AMS PosT-BACCALAUREATE P ROGRAM takes
potential medical students who have been impeded by
special circumstances in their application to medical
school and helps them prepare to try again. Cosponsored
by the Associated Medical Schools (AMS) of New York
and the University at Buffalo, the program was started in
1991 to promote minority enrollment in the state's
medical schools. Currently, it enrolls 14-20 economically disadvantaged or minority students each year.
"The Post-Baccalaureate Program is a well-coordinated, structured program of courses, counseling,
tutorials and support that provides students with the
opportunity to gain requisite skills for entry into medical
school," says Carolyn Hamilton, EdD, assistant dean
for minority affairs at the University at Buffalo School
of Medicine and Biomedical Sciences. "It was designed
for applicants who have been denied admission to medical school, to assist them in improving their performance
in academic areas where they have shown weakness."

Qualities of Character
Enrollment in the program is by invitation, with admissions directors at eight participating AMS institutions
referring students based on their positive showing during preadmission interviews. Once students gain entrance into the program and successfully complete all of
its requirements, they are guaranteed acceptance into the
medical school that recommended them .
"These applicants represent a diverse cross section of
the state's minority population," Hamilton says. "The
chief thing they have in common is that they're talented,
but they may be lacking in one area or another. The
admitting school refers them to the Post-Baccalaureate
Program because they show great potential, and because
the school recognizes that if they had had that certain
'missing piece,' they would have been accepted."
The program allows students to demonstrate abilities
that may not be highlighted during a typical medical
school admissions interview, says Adrian Jones, PostBaccalaureate Program coordinator at UB.

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Jones believes that because there are so many highquality applicants vying for a limited number of medical
school slots, the interview process is geared to exclude
rather than recruit students. This approach, he says,
tends to work against economically disadvantaged
candidates, who may be highly competent but may not
have had exposure to the types of experiences and
opportunities available to more affluent applicants.
"Every person in th is program has had to deal with
difficult circumstances and challenges,'' Jones says. "The
fact that they've been able to function and to perform so
well academically demonstrates qualities of character
that can't always be measured in a one-hour interview."

c

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"

�AChance to Thrive
ow in his second year at UB's medical school, George
Figueroa typifies the sort of person for whom the PostBaccalaureate Program was designed. As the youngest
member of a large, close-knit family, Figueroa has
carried the primary responsibility of financing his
own education.
With the aid of vari ous grants and loans,
and sometimes two jobs
at a time, Figueroa man aged to put him self
through school at Rochester Institute of Technology. As undergraduates, he and his wife,
Carol, planned a future
that would include a
family medical practice
for him and a network
analyst's career for her.
Figueroa concentrated on maintaining a record of solid academic
achievement while keeping his family afloat financially. Every spare
moment was consumed
by school, work and the
prerequisite hours of
community service so
necessary to distinguish
applicants in the eyes of
medical school admissions officials. For the Figueroas, the
Second·year student
George Figueroa
dream was well worth the sacrifice.
works with Carolyn
Figueroa's first application to mediHamilton, EdD, to
cal school was declined because his
provide other
Medical College Admission Test
students with the
(MCAT) scores were not competitive.
support he knows will
Determined to succeed, he enrolled in
make adifference.
an MCAT preparation course and repeated the test. Although he was able to improve his
score, the application period had passed by the time he
completed the course, forcing him to wait another year.
Figueroa's second attempt was only slightly more
successful, garnering interviews by interested admis-

sions officials but still no acceptance letters. "They say
that every time you apply to medical school and get
turned down , your odds of acceptance diminish," he
says. "At the time, I was doing customer support for a
cellular company and I was miserable. When my second
try didn 't pan out, l was very discouraged."
Growing increasingly anxious, Figueroa began researching other options, including a year-long graduate
program in medical science at Hahnemann University
in Philadelphia. While enrollment in the program
offered a chance at medical school admission, there
were no guarantees. Moreover, financial constraints on
the famil y meant that Figueroa would have to leave his
wife and two young sons behind in Rochester while he
moved to Philadelphia for the year. Despite the drawbacks, he decided to go for it.
"Being away from the famil y was the most difficult
part," Figueroa says. "Philadelphia was a 14-hour bus
trip from Rochester, and I couldn 't go home very
often-only about once every four to six weeks. Our
youngest wasn't even a year old when I started the
program, and every time I'd come home he'd be bigger,
taller and heavier. "
Though grueling, the experience deepened
Figueroa's resolve to achieve his goal. After completing the program in Philadelphia, he was ready to try
again. This time he was placed on several medical schools'
waiting lists, and most important, although his application was declined by UB, the university invited him to
enroll in the Post-Baccalaureate Program.
" It was an opportunity I couldn't refuse," Figueroa
says. Although the program would require him to spend
another year in preparation, he was assured of admission
to the UB School ofMedicine and Biomedical Sciences if
he successfully completed all program requirements.
"The [Post-Baccalaureate] Program helped me immensely," he says, in retrospect. "I can see that if I'd
gotten into medical school without the coursework, I'd
have been like a guppy in a sea of sharks. All the pre-work
gave me a much stronger foundation and has made the
current work much easier. For one thing, I don 't have to
spend so much time focusing on the minutia, so I can
concentrate on some of the more difficult concepts. "
In addition to keeping up with his hefty class schedule, family life and part-time job, Figueroa is committed
to helping others navigate the path to medical school.
CONTINUED

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New Institute for lasers,
Photonics and Biophotonics

N

GoLDBAUM

he University at Buffalo has established
a new multidisciplinary institute to
conduct research designed to harness
the power oflight in a broad spectrum
of applications and potential products,
ranging from cancer therapy to telecommunications.
The idea behind the formation of
the Institute for Lasers, Photonics and
Biophotonics is to foster economic
growth in Western New York by tapping into UB's strengths in lasers, biotechnology and photonics (the use of photons,
instead of electrons, as a medium for processing information).
"The medical school is very excited about
the institute," says Bruce A. Holm, PhD, the
school's senior associate dean, and professor
of pharmacology and toxicology and gynecology-obstetrics. "Our interest is twofold,
related to the development of new therapeutic modalities for the treatment of conditions
ranging from cancer to skin disease, and to
the opportunity to use the institute as a
mechanism for establishing a true biomedical engineering program that will expand
our current activities in other areas."

"Nanoclinics" aBillionth of aMeter in Size
The Institute for Lasers, Photonics and
Biophotonics- which will be headed by Paras
Prasad, PhD, SUNY Distinguished Professor
in the departments of chemistry and physics
and Samuel P. Capen Chair in the Department of Chemistry- has its roots in UB's
Photonics Research Laboratory (PRL), established in 1990 and considered one of the
most advanced and comprehensive facilities
for photonics research in the United States.
One of the most promising technologies

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developed by institute researchers is the
nanoclinic, described by Prasad as "the
world's smallest clinic." This tiny
nanobubble-about a billionth of a meter in
size- is designed to perform any one of a
number of varied diagnostic or therapeutic
tasks by carrying a chemical treatment or
diagnostic tool to a specific site in the body.
In cell-culture experiments, the group has
already developed one formulation of the
nanoclinic that selectively destroys cancer
cells without the use of chemotherapy.
"The entire purpose of this is to take the
therapy inside the cancer cell," says E. J.
Bergey, PhD, research associate professor of
chemistry at UB. "The advantage of the
nanoclinic concept is that we can target specific cancers and effect the therapy from
within the cancerous tissue or cell, minimizing collateral damage to the healthy
cells. The size of the nanoclinic is critical to
allowing for efficient distribution throughout the body."
The nanoclinics have the
potential to be remarkably
versatile in carrying optical
probes, drugs, genes, inorganic compounds, controlledrelease substances and other
diagnostic and therapeutic
agents. In addition, hormones,
antibodies or other appropriate chemical agents can be attached to the surface to selectively target specific types of
cells, according to Bergey.
"The nanoclinics can be of

SUNY Distinguished Professor Paras
Prasad, PhD, heads new institute.

'I

tremendous benefit in the noninvasive treatment of early-stage cancer and infectious
disease, as well as in gene therapy and
oxygenation of damaged tissues," he says.
To date, the institute has developed a
working prototype and samples of the
nanobubble material, both of which are
available for testing.

The Big Picture
In the years ahead, the Institute for Lasers,
Photonics and Biophotonics will build on its
existing network of partnerships with both
industry and research. Within the university,
it already has ongoing relationships with
other photonics research programs in the
School of Dental Medicine, the School of
Engineering and Applied Sciences, and the
Department of Physics. In addition to

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�Support for Two New Centers an~
\

$3 . 8 million gr ant from Howard Hughes Medical Institute

f
B v
L o I S
four-year, $3.8 million award
Medicine and Biomedical
from the Howard Hughes
Sciences. "It reflects well
B A K E R
Medical Institute has been
not only on the quality of
granted to University at Buffalo ' s Bruce Holm's proposal, but also on
School of Medicine and Biomedical the university and its reputation.
Sciences to speed development of two
"In making the award to VB,
new research centers.
the Howard Hughes Medical InstiThe award will fund research sup- tute reviewers cited a number of
port for five new faculty members and strengths," Wright notes.
capital equipment for a new Center for
"In addition to the quality of the
Single-Molecule Biophysics, as well as proposal itself, UB's commitment to
facilities for that center and a new Center the two centers was specifically
noted, as was the school's recent growth in
for Genomics and Proteomics.
extramural
grant support. The institute
In recent years, UB has invested nearly
$9 million in building renovations and citing VB as 'an institution rapidly on the

equipment purchases that are vital to the two
new centers, in addition to providing more
than $2 million annually in salary to faculty
members associated with the programs.
The review of UB's grant request to the
institute noted that "the institution has
undergone recent growth, and extramural
(external ) grant support has increased
significantly-evidence that this is an
institution rapidly on the rise. "
Forty-one medical schools were selected
for funding through the institute's Biomedical Research Support Program for
Medical Schools from 105 that submitted
proposals. UB's award is the second largest in
the program. Only UCLA School of Medicine, the University of Michigan Medical
School and Yale University School of Medicine-which each received $4 million-were
granted more funding.
Bruce Holm, PhD, senior associate dean in
the medical school and author of the grant
proposal, will serve as the project director.
"This is no ordinary grant award," says
John Wright, MD, dean of the School of

rise' are encouraging words, indeed. We
congratulate Dr. Holm and the faculty for
this outstanding achievement."
The Center for Genomics and Proteomics
will be a joint effort with senior investigators
located at Roswell Park Cancer Institute and
at the Hauptman-Woodward Medical
Research Institute. This state-of-the-art
center will enhance existing expertise in the
areas of human , mouse and microbial
genomics. Capabilities will include
microarray and mass spectroscopic analyses
of genes and proteins that will enhance
understanding of cancer biology, microbial
pathogenesis and human-disease genes.
The Center for Single-Molecule Biophysics will emphasize work on computational
chemistry, structural biology and molecular
biology. Five new faculty members will be
hired to further develop this area. The goal,
Holm says, is to study proteins and other
macromolecules in space and time. Results
from such research will provide insights into
protein structure-function relationships
that can solve clinical problems.

...

•

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Bruce Holm PhD, senior associate dean in the School of Medicine
and Biomedical Sciences, will serve as the project director.
Current work in this area is being applied
to cardiac function, synaptic transmission,
electrolyte secretion and tumor suppression.
Anthony Auerbach, PhD, and Frederick
Sachs, PhD, both proTHE REVIEW OF UB's
fessors of physiology
and biophysics, will GRA T REQUEST TO THE
codirect this center.
INSTITUTE NOTED THAT
The work will be "THE INSTITUTION HAS
overseen by an adviUNDERGONE RECENT
sory board composed
GROWTH, AND EXTRAof Holm; Wright;
MURAL (EXTERNAL)
John Hay, PhD, associate provost for reGRANT SUPPORT HAS
search and chair of INCREASED SIGNIFIthe Department of
CANTLY-EVIDENCE
Microbiology; Harold
Strauss, MD , chair of THAT THIS IS AN
the Department of INSTITUTION RAPIDLY
Physiology and BioON THE RISE."
physics; David Hohn,
MD, director of the Roswell Park Cancer
Institute; as well as the codirectors of the
two centers.

S prin g

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~uvenile

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Arthritis Study

reported on a study being led by Nadine Fisher,
EdD, which, to date, has shown that children
with juvenile arthritis who take part in an individualized program of resistance exercise
experience significant improvement in their
ability to function. The article inadvertently
omitted Fisher's coinvestigators: Kathleen M.
O'Neil, MD, a University at Buffalo associate
professor of clinical pediatrics affiliated with
Kaleida Health System's Children's Hospital of
Buffalo; and Vylma Velazquez, MD, pediatric
fellow. Fisher, who designed the exercise program, is an assistant professor of occupational
therapy and rehabilitation at UB.
4D

OF

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students' previous training and prepare them for the
rigors of medical school."
Students begin the program with a six-week summer

THE W I NTER 2000 ISSUE of Buffalo Physician

DE C REE

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19

Somehow, he finds time to tutor anatomy students enrolled in the Post- Baccalaureate Program and to function
as treasurer of the Student National Medical Association.
With other members of the association, he is involved
in an effort to introduce a peer-mentoring program into
UB's medical school. This informal program would link
local undergraduates with medical students, who would
answer questions and offer insight into various aspects of
medical school admission and campus life.

enrichment program in math and science. Continuing
through the academic year, each student is placed in a
14-credit course of study tailored to meet his or her
specific needs. The curriculum also includes daily tutorial sessions and a summer program of prematriculation
studies offered on the campuses of each referring school.
Participating institutions include Albany Medical
College, Albert Einstein College of Medicine, New York
Medical College, SUNY at Buffalo School of Medicine
and Biomedical Sciences, SUNY Health Science Center
at Brooklyn, SUNY Health Science Center at Syracuse,
SUNY Health Sciences Center at Stony Brook and the
University of Rochester.
In most cases, tuition and fees are waived for students
accepted into the program. Additionally, students are
provided with monthly stipends for room and board
and books.
"The Post-Baccalaureate Program is proving to be
very effective in helping underrepresented students get
into medical school," Hamilton says. "Of the 127 to
participate during the first eight years of the program,
115 subsequently gained admission.
"The program provides the mechanism, but it's really
up to the students to benefit from this opportunity. To
succeed, they have to be motivated and focused." 4D
The AMS Post-Baccalaureate Program is supported by the
Josiah Macy ]r. Foundation and the New York State
DepartmentofHealth. For additional information, contact
Carolyn Hamilton, EdD, director, or Adrian ]ones,
coordinator, at (716) 829-2802.

Filling in the Gaps
The Post-Baccalaureate Program at UB offers a comprehensive curriculum ofbiology, physics, chemistry, mathematics and English, as well as a variety of electives and
instruction in organizational and study skills.
"Individual coursework varies, depending on the
student," says Hamilton. "All of these students are
highly qualified, but each needs strengthening in certain areas. One student may need extra attention in
chemistry, while another may need to improve
performance on the MCAT. Still another may sign up
for an elective course on the Greek and Latin roots of
scientific terminology. The goal is to fill in gaps in the

22

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2 0

giving its partners access to a broad range of scientific
instruments and technologies and world-class testing
and research facilities, the institute will offer technical
expertise, joint efforts to develop new products, short
courses on innovative technologies, and training and
recruitment opportunities. For the university, the institute will offer an interdisciplinary graduate program of
study, postdoctoral training, visiting-faculty programs,
summer programs, and international collaborations
and exchange programs.
4J:)

�1111111 nraJclu

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S. Mouchly Small Education Center
AN EDUCATION CENTER in honor
of S. Mouchly Small, MD, has
been opened in the Department
of Psychiatry at Erie County
Medical Center.
Small, who died in
1996, was an internationall y known ps ychiatrist and educator
who chaired the Universityat Buffalo's Department of Psychiatry from 1951 to 1978.
Under his leadership, the department grew from a handful of
faculty members into a major
national training and research
center of more than 150 profes-

sionals. In the early 1950s, Small
founded the Muscular Dystrophy Association and served as its
national president from 1980 to
1989 and as chair of
its executive com mittee until hi s
death. In the mid1950s, he wa s in strumental in organizing the Erie County Mental Health
Board and was its
first director. In this capacity, he
helped obtain funding for Buffal o General Hospital's Community Mental Health Center and
played an integral role in estab-

Musicians, artists, dancers,
actors, athletes, scholars ...
we all love Nichols.

E

w s

lishing the State Alcoholism
Research Center in Buffalo.
Small published extensively
and was author of A Handbook
of Psychiatry, a 1943 book that
was widely viewed as an authoritative guide to ps ychiatric
theory and practice.
In recognition of his outstanding contributions to his
field , Small received the E. B.
Bowis Gold Medal from the
American College of Psychiatrists, the Distinguished Service
Citation from the American Psychiatric Association and UB's
Stockton Kimball Award. In May
1997, UB 's Medical Alumni
Association posthumously presented Small with the Walter P.
Cooke Award.
The award, given to nonalumn i, recognizes notable and
meritorious contributions to

the university that influence its
growth and improvement.
The 3, 000- squa re-foot S.
Mouchly Small Education Center includes a conference room
and library, administrative offices
for the residency-training program and teaching space for
clinical services. Included in the
center is an area for journals and
textbooks, as well as online
computer services.
The center, which was established through benefactors and
donors, was formall y dedicated
on October 29, 1999. Speaking
at th e ceremon y were Su san
McLeer, chair of the Department
of Psychiatry, and John Wright,
dean of the School of Medicine
and Biomedical Sciences. In attendance to cut the ribbon during the ceremony was Small's
widow, Mrs. Sophie Small. &lt;:t)

Rosenfeld Receives Distinguished Service Award

• State of the art visual and
performing arts center

George Rosenfeld, MD, clinical associate professor of pediatrics at the

• Exceptional college
placement record

University at Buffalo School of Medicine and Biomedical Sciences, has

• Challenging curriculum with 17
advanced placement courses

at Kaleida Health System's

• Comprehensive community
~~~~_.~"'· service program
• More than 60 sports teams

been presented with a Distinguished Service Award from the medical staff
Children's Hospital of Buffalo.
Rosenfeld, a member of the
staff at Children's for 48
years, has been a stalwart in

• Average class size of 15

the hospital's teaching pro-

• Financial aid available

gram and has served as chair

Only one investment
lasts a lifetime
Coeducational grades 5-12

875-8212
1250 Amherst Street
Buffalo, NY 14216
www.nicholsnet.net

of its Lab Committee for the
past 25 years. In addition, he
and his wife established the
George and Harriet Rosenfeld

'

leh to right: Theodore I. Putnam, MD, George Rosenfeld,
MD, Mrs. Harriet Rosenfeld, and Bernard Eisenberg, MD.

Award and Grant, which honors the outstanding laboratory accomplishments of an individual on staff at Children's and offers a grant on a
competitive basis to physicians interested in research.
"George is a fine example of what we would want our resident physi-

Acceptance granted to qualified students
without regard to race, color, religion or
national origin.

24

l1ffal1 Hysicia1

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cians to emulate," says Theodore I. Putnam, MD, chief of the Division of
General Pediatrics. "This award is presented to him for his long and
faithful service to Children's Hospital."

4D

�New Online Catalog for Libraries
ONCILL provides integrated access to
medical resources

medical practitioners at
the forefront ofthe digital revolution is the mission of the
Library Consortium of Health Institutions in Buffalo
(LCHIB). In 1993, electronic access to medical information in our community was forever redefined when the
consortium unveiled HUBNET (Hospitals and University at Buffalo Network). Today, an expanded HUB ET
delivers such resources as MEDLINE, QMR, selected full-text
journals, reference texts, drug information and consumer resources directly to homes, offices and clinical and hospital sites.
The newest component of HUBNET is a
Today, anyone with a
shared electronic online library catalog that
web browser and
replaces the outdated card catalogs. The sysconnection to the
tem-named 0 CALL for the Online Catalog
Internet can search
of LCHIB Libraries-was first implemented at
EEPING WESTERN NEW YORK

the library catalogs
of any of the LCHIB
participating
hospital libraries,
24 hours aday, by
visiting the ONCILL
web site.

Kaleida Health System libraries with support
provided by a $200,000 grant from the
National Library of Medicine (NLM).
In 1998, LCHIB received a second grant
from the NLM for $298,000 to include the
card catalogs of the libraries at Roswell Park
Cancer Institute, Erie County
Medical Center, Kaleida Health System's
Children's Hospital of Buffalo and the
Catholic Health System's Sisters of Charity
Hospital, Mercy Hospital and Kenmore
Mercy Hospital.
Today, anyone with a web browser and
connection to the Internet can search the
library catalogs of any of the LCHIB participating hospital libraries, 24 hours a day, by
visiting the ONCALL website at http://oncall.buffalo.edu.
The Library Consortium of Health Institutions in Buffalo is
comprised of most of the medical libraries in Buffalo, as well as
the UB Health Sciences Library. To learn more about the consortium's HUB ET and ONCALL services, contact Martin E.
Mutka, director of the LCHIB at (716) 829-3900, ext. 143, or
e-mail him at mmutka@acsu.buffalo.edu.

-PAT

PRIOR

�PATHWAYS

EDITOR's NOTE:

The following are brief introductions to faculty who have

recently joined the University at Buffalo School of Medicine and Biomedical
Sciences. Additional profiles will be published in future issues ofBuffalo Physician.

Chair,
Department of Biochemzstry

Professor,
Department of Social and
Prn·entive Medicine

.loseph De.lames, MD

Donahue joined UB's faculty as a

biochemistry in 1974. While

Clinical Assistant Professor,
Department of Family Medzmze

Social and Preventive Medicine in

in Florida, he was also on the

Dejames joined the University at

july 1997. He earned a bachelor of

staff of the C.V. Whitney Marine

Buffalo's Department of Family

science degree in biology from

as assistant professor of

KennethM.
Blumenthal, PhD

Richard Donahue,
PhD, MPH

professor in the Department of

Medicine in August 1999. In

Providence College, Providence,

professor of molecular genetics,

Blumenthal became assistant

addition to practicing at Niagara

RI, in 1976 and a master's in public

biochemistry and microbiology

professor of biological chemistry

Family Health Center, he is work-

health from the University of

at the University at Cincinnati,

Michigan in Ann Arbor, MI, in

Kenneth M. Blumenthal, PhD,

Research laboratory.

at the University of Cincinnati

ing with UB's Family Medicine

has been named chair

College of Medicine in

Residency Program, teaching

1981. In 1983, he completed a doc-

of the UB Department

1976 and was promot-

residents, conducting research

torate in epidemiology at the Uni-

of Biochemistry, effec-

ed to full professor in

and serving as associate coordina-

versity of Pittsburgh, Pittsburgh,

tive August 1, 2000.

1986. While there he

tor for the Clinical Practice of

PA. Prior to joining the faculty at

A specialist in the

was honored for out-

Medicine course for first-year

UB, Donahue was a professor of

study of protein struc-

standing teaching for

medical students. De)ames triple

epidemiology and public health

tures, Blumenthal is

three consecutive years.

majored in biology, philosophy

at the University of Miami School

currently

At the time of his de-

and African-American Studies at

of Medicine in Miami, FL. His

parture, he was chair
ofthe medical school's

Boston College, where he gradu-

research interests include the epi-

ated in 1990. In 1992, he earned a

demiology of insulin resistance,

National Institutes of Health

Committee on Basic Research and

master of arts degree in American/

coronary heart disease and diabe-

(NIH) grant to investigate the

associate director of the Ohio

Puerto Rican Studies at UB. He

tes; primary prevention of diabetes

interaction of peptide blockers

Center for Computer-Aided

completed his medical degree at

in youth; and coronary heart dis-

with gastric chloride channels.

Molecular Design, which is

UB in 1996 and in 1999 served his

ease in people with Type 1 diabetes.

Blumenthal earned a bach-

housed at the university. He

family medicine residency at the

elor of science degree in chem-

also served three terms on the

university, where he was chief

istry from the University of

university-wide research council.

resident in 1998-1999. His clin-

Wisconsin in 1967 and a PhD

Blumenthal is a member of

ical/academic interests include

in biochemistry from the Uni-

NIH site-visit teams and a past

underserved populations, the

principal

investigator on a K.
four-year $596,000

BLUMENTHAL

Sarah C. Finnegan,
MD, PhD
Assistant Researc/z Professor,
Department of Neurology
Department of Pharmacology
and Toxicology

versity of Chicago in 1971. He

member of three NIH study sec-

impact of lower socioeconomic

completed a three-year NIH

tions. He serves on the editorial

status on health, and teaching

postdoctoral fellowship in bio-

board of the Journal of Biological

clinical skills to medical students.

logical chemistry at the Univer-

Chemistry and has authored

July 1999 as an assistant research
professor and Buswell Fellowship

Finnegan joined UB's faculty in

sity of California at los Angles

or coauthored 50 papers in

School of Medicine before join-

refereed journals and five

recipient in the Department of

ing the faculty of the University

book chapters.

CD

Neurology. She also holds a sec-

of Florida College of Medicine

L o r s BA K E R

ondary appointment in the Department of Pharmacology and

JoHN YEH, MD, WILL JOIN UB AS CHAIR OF OBSTETRICS AND GYNECOLOGY oN MAY 1, AND
KENNETH BLUMENTHAL, PHD, WILL BEGIN AS CHAIR OF BIOCHEMISTRY ON AUGUST 1.

2 ..

26

1111111 Hysiciu

Spring

20 00

�Toxicology, where she works with

Psychiatry, Faculty of Medicine

Dennis Higgins, PhD . Finnegan

since 1971 , joined the Department

earned a bachelor of science de-

of Family Medicine in Ma y 1999.

gree in chemistry at

His clinical affiliation is with Erie

SU Y at Binghamton

County Medical Center' s Divi-

in 1984, after which

sion of Chemical Dependency.

she earned MD/PhD

Giordano completed his under-

(physiology) degrees

graduate premed studies at UB in

at UB in 1994. She

1954, after which he earned his

Chair, Department of
Radiatwn Medicine
Roswell Park Cancer lnstit11te

interned in internal

medical degree from the Univer-

Prior to joining the University at

human cervical cells by ionizing

medicin e at Millard

sity of Padua, in Padova, Italy, in

Buffalo and Roswell Park Cancer

radiation; in vitro screening

Fillmore

Ho s pital

1960. He completed his residency

Institute in August

of potential chemo-

from 1994-1995 and

in psychiatry at Buffalo State Hos-

1999, Kuettel served as

preventive

completed residency training in

pital in 1964. From 1976 to 1991 ,

associate professor of

using human prostate

neurology at UB, serving as chief

he served as chief of psychiatry at

radiation medicine and

epithelial cells; and

resident in 1998. She then com-

Mercy Hospital in Buffalo, and

anatomy and cell biol-

investigations of a new

pleted pediatric residency train-

from 1993 until May 1999, as

ogy in the Department

tumor suppressor gene

ing, also at UB, in 1999. Finnegan,

medical director of Addiction

of Radiation Oncology

in prostate cancer.

who practices at Kaleida Health 's

Medicine at Sisters Hospital, also

at Georgetown Univer-

Children 's Hospital of Buffalo, is

in Buffalo.

S . FI NN EGAN

Michael R. Kuettel,
MD, MBA, PhD

of the National Board of
Medical Examiners and the

Professor and Chair,
Department of Radwtion
Oncology
University at Buffalo

American Board of Radiology
(radiation oncology).
Kuettel's research interests
include the molecular mechanisms of neoplastic transformation of human prostate and

At Roswell Park Can-

interested in caring for children

sity in Washington, D.C. M . K u
Kuettel received his

with neurological disorders, in-

medical degree from Northwest·

cluding those with developmental
disabilities related to perinatal
brain injury. Her research inter-

Kenneth Hoffman,
PhD Associate Professor,
Department of Neurosurgery
Toshiba Stroke Research Center

ests involve elucidation of factors promoting the survival and
regeneration of adult human neurons that may hold implications
for degenerative disease processes.

Hoffman, who joined UB 's faculty
in September 1999, earned his
bachelor of arts degree in physics,
summa cum

agents

ET T E L

cer Institute, Kuettel
heads the Department

of Radiation Medicine, a referral

ern University Medical School in

and resource center to health·

Chicago, ll, and completed his

care facilities across the country

residency training in radiation

and Canada that offers cancer

oncology at The Johns Hopkins

patients comprehensive care and

Hospital, Baltimore, MD. He then

innovative treatments such as the

earned a PhD in anatomy and cell

gamma knife, photodynamic

biology from the Medical College

therapy and brachytherapy. &lt;L;)

of Wisconsin. He is a Diplomate

DEBORAH

PETTIBO~E

laude, from St.

Louis Univer-

P•ul B. Qlord•no, MD

sity, St. Louis,

Assistant Professor,
Clinical Family Medicwe
Department of Family Medzc111e

MO, in 1976,

Waltham, MA, in 1984. Prior to

tomographic images, or temporal

and a PhD in

coming to UB, he was an associate

3D data sets, with a focus on vascu -

physics from

professor in the Department of

lar or luminal structures. Specifi-

Giordano, a clinical assistant pro-

Brandeis

Radiology at the University of

cally, he is interested in determina-

fessor in UB ' s Depa rtment of

University in K. H o FFMA N

Chicago. Hi s research interests

tion of 3D vascular structures

include developing ways to ana-

from two or more views, quanti -

lyze and present radiographic im-

tative analysis of these structures

age data, either projection images,

and alignment of them with their
projections. He is al so interested
in the segmentation and quantitation of bone, vascular structures and the colon from CT data
sets. Currently, he is funded by

Spring

2000

lu ffalo Pbysici11

21

�PATHWAY

.JohnYeh,MD

1983. Following a residency at

research and strategic planning.

study the role of growth factors

Chair, Department of
Obstetrics and Gynecology

Beth Israel Hospital in Boston,

He also served as executive

in human fetal ova development

he completed a fellowship in

director

John Yeh, MD, professor and

fertility and reproductive endo-

Women's Health Pro-

vice-chair of the Department of

crinology at Boston's Brigham

gram at Regions Hos-

Yeh is coauthor of a

Obstetrics and Gynecology at the

and Women's Hospital.

pital in Minneapolis

1991 book, Legal Aspects

the

and has grants pending for
cervical cancer research.

University of Minnesota, has

In 1987, Yehjoinedthefaculty

and was director of

of lnferlility, and is writing

been named chair of the UB

of Harvard Medical School, where

the residency pro-

a book on growth factors in
reproductive medicine. He

Department of Gynecology and

he spent years conducting re-

gram in obstetrics

Obstetrics, effective May 1, 2000.

search in the field of reproductive

and gynecology.

Yeh earned an AB degree

endocrinology, teaching and

from Harvard University in 1979

treating patients. In 1997, he

has been funded by

and a medical degree from the

took the position at the University

the National Institutes of Health

University of California at San

of Minnesota, where he was

since 1989. Currently, he is prin-

Diego School of Medicine in

responsible for the department's

cipal investigator on a grant to

also has published many

Yeh's research J · Y

research abstracts, book

EH

chapters and scientific
studies in professional journals.
Lo s

BAKER

ests include the regulation of neu-

his PharmD

Stanley H. Kim, MD

to study methods to improve

rotransmitter release and produc-

degree at the

radiologic colon polyp detection.

tion in the nervous system; regula-

University of

Clinical Asszstant Professor,
Department of Neurosurgery

tion of cytokine production and

Arizona Col-

Kim, who practices at Kaleida

the National Institutes of Health

release from cells of the nervous

lege of Phar-

Health System's Millard Fil-

Tracey Ignatowski,
PhD

and

and

macy in Tuc-

lmore Gates Hospital, joined

interactions among proinflam-

son, AZ, in

UB's faculty as an assistant

Research Assistant Professor,
Department of Pathology

matory cytokines, adrenergic re-

Ignatowski joined UB's Department of Pathology as a research
assistant professor in
May 1999 and has
served in a similar
capacity in the Department of Anesthe-

immune

systems;

sponses and opioid responses

earned a bachelor of

T. I G NATOWSKI

M. KALSMAN

1991 and his

professor of neurosurgery in

medical de-

July 1999. A specialist in inter-

gree from the

ventional neuroradiology, Kim

during antidepressant drug ad-

University of Arizona College of

earned his bachelor of science

ministration, providing possible

Medicine, also in Tucson, in 1995.

degree at the University of

mechanisms of action for antide-

He completed his family practice

Michigan in Ann Arbor, MI, in

pressants in the treatment of de-

residency in Salt Lake City, UT, at

1986 and his medi-

the University of Utah, serving as

cal

chief resident in 1997-1998. He

Wayne State Uni-

then completed a rural medicine

versity in Detroit in

during persistent pain, as well as

pression and chronic pain states.

siology since 1997. She

degree

from

fellowship in Tacoma, WA, in 1999.

1990. He served his

science degree in bio-

Michael Kalsman, MD,
PharmD

logical sciences at UB

Clllltcal Associate Professor,
Department of Family Medicine

His primary interest is in rural

residency training

medicine with an emphasis on

in neurosurgery at

obstetrics. He is also interested in

Wayne State Uni-

researching the use of the Internet

versity from 19911993 and at The

in 1990 and a PhD in

28

of

pathology at the university in

Kalsman joined the University at

1995. From 1995-1997 she was a

Buffalo's Department of Family

postdoctoral fellow at the Univer-

Medicine in September 1999. He

Ohio

sity of Rochester in the Depart-

practices

at the University Pri-

Columbus, OH, from 1995-1999.

ment of Pharmacology and Physi-

mary Clinic and is affiliated with

In addition to interventional

ology. Ignatowski's research inter-

Olean General Hospital. He earned

neuroradiology, Kim's clinical

luflale Pbysiciaa

Spring

2000

as a medical resource.

State

STANLEY KIM

University

in

�idency Pro-

NewYork,NY. He received a medi-

pita!. Her interests include patient

complex spine surgery and mini-

gram and as-

cal degree from George Washing-

education and training medical

mally invasive spine surgery.

sistant professor in the De-

ton University School of Medicine

students and residents.

in Washington, D.C., and com-

partment of

pleted residency training in sur-

Susan Y. Kim, MD

Social

and

gery and plastic surgery at St.

Daniel Rifkin, MD

Asststant Professor,
Departmerzt of Radtation Oncology
University at Buffalo

Preventive

Luke's/Roosevelt Hospital Center.

Assistant Professor,
Department of Neurology

and research interests include

Department of Radtation Medicine
Roswell Park Cancer Institute

Kim rejoined Roswell Park Cancer Institute
(RPCI)and
UB as an assistant professor
of radiation
medicine

LI

He then served a fellowship in

Medical Director, Sleep Disorder
CerJter of Western New York

head and neck oncology and sur-

bachelor of science degree in bioi-

gery at Memorial Sloan-Kettering

ogy, magna cum laude, at the Uni-

Cancer Center in New York, NY.

versity of Southern California in

Loree is board certified by the

Los Angeles, CA, in 1979 and

American Board of Plastic Surgery

his medical degree at St. Louis

and the American Board of Sur-

University School of Medicine

gery. His research interests include

in St. Louis, MO, in 1984. He

thyroid cancer, microsurgery and

then completed a master of pub-

in

Rifkin joined the UB's faculty in
August 1998 and serves as medical
directorofthe Sleep Disorder Center of Western

lard Fillmore Hospital. Rifkin
earned a bachelor of arts degree,

free-tissue transfer.

cum laude, in religion from Ham-

ilton College, Clinton, NY, in 1988,

sity of Michigan in Ann Arbor,
SUSAN

KIM

gist, she is a
graduate of the University of

MI, in 1989. Li's research interests

Nilsa M. Martinez:, MD

and a medical degree from

are preventive medicine, public

Clinical Assistant Professor,
Department of Family Medictne

Dartmouth Medical School,

health and chronic disease.

Vermont School of Medicine in
Burlington, VT.

She completed

her residency at St. Luke's Medical
Center in Chicago, IL, and is board
certified by the American Board of
Radiology. Most recently, she
founded and headed the stereotac-

Thom R. Loree, MD
C!tief, Divtsion of Head and Neck
Surgtcal Oncology/Plastic and
Reconstructive Surgery
Department of Surgery
Roswell Park Cancer Jnstttute

Israel Medical Center in New York

Assistant Professor,
Departmertt of Surgery
University at Buffalo

City. At RPCI, she is practicing

tic radiosurgery program at Beth

ew York, located

at Kaleida Health System's Mil-

lic health degree at the Univer-

September
1999. A radiation oncoJo-

Medicine.
He earned his

Hanover, NH, in 1992. He served

Martinez joined the

his residency in neurology

University

Buf-

at Strong Memorial Hos-

falo Family Medicine

pital, Rochester, NY, where

Faculty Associates in

he was chief resident in

at

She

1996. In 1997,

practices at the Univer-

he completed a

October

1999.

sity Primary Clinic in

postdoctoral

Houghton, NY, and is

clinical and re-

affiliated with Olean
Hospital.
General

.

MARTINEZ

search fellowship in sleep

Loree was appointed chief of the

Martinez earned her bachelor of

medicine and clinical

neuro-oncology, including gamma

Division of Head and Neck Surgi-

science degree in neurosciences at

neurophysiology at the

knife radiosurgery.

cal Oncology/Plastic and Recon-

the University of Rochester in

University of Mich-

Rochester, NY, in 1990 and her

igan Medical Center

Carl LI,MD

structive Surgery at Roswell Park
Cancer Institute (RPCI) in Janu-

medical degree at Boston Univer-

in Ann Arbor, MI. His

ary 2000. Loree,

sity School of Medicine in Bos-

clinical research inter-

who is also an

ton, MA, in 1994. She completed

ests include all aspects

assistant pro-

her family practice residency at

of sleep disorders

fessor of sur-

St. Joseph's Hospital Health Cen-

medicine, with a pri-

gery

Associate Director,
General Preventtve Medicine
Residency Program
Assistant Professor,
Department of Social and
Preventive Medicine

Li joined UB's faculty in March
1999 as associate director of the
General Preventive Medicine Res-

Rifkin is medical
director of the
Sleep Disorder
Center of Western
New York. His
clinical research
interests include
all aspects
of sleep
disorders
medicine, with a
primary focus on
the effects of
hypoxia on
the brain.

UB,

ter in Syracuse, NY, in 1997. Prior

mary focus on the ef-

came to RPCI

to coming to UB, Martinez was

fects of hypoxia (often associated

from St. Luke's!

affiliated with the Hospital Inter-

Roosevelt Hos-

nists Group at St. Joseph's Hos-

with obstructive sleep apnea) on
the brain.
&lt;!;)

at

pital Center in T. LoREE

Spring

2000

I DIIII O Pbys i c i 10

29

�DEVELOPMENT

N

E

w s

Salute to the Class of 194~
By Li nda J . Cor de r , PhD. CFRE

\S_ \'1

lN
OF

r 1, I

Sin) \J.G~I 1 11· H 'l\\ \II. Shortly

after arriving, I switched on the rental car's radio and
heard a narrator describing the USS Arizona in its
underwater tomb at Pearl Harbor, barely a mile from
Honolulu's airport. Then I realized the date was December 7th. The broadcast, from Washington, D.C.,
was a retrospective on the 1941 surprise attack that
catapulted our nation into the Second World War. For
me, that war was just a chapter in my history book, as
vague as Vietnam is to our current students. I decided
to visit the memorial, to imagine what medical students of that era might have felt as they tried to come to
terms with the brutality of war while dedicating themselves to becoming physicians.
Members of the Class of 1945 were UB's first to
enroll after the U.S. entered the war. Seven months to
the day of that bombing-July 7, 1942-they began
their medical education at 24 High Street. They were
on a fast track-three short years. All their youthful
energy was bent toward learning the skills of healing,
knowing that their most crucial tests might come
under battlefield conditions far from home.
The class bonded in
a way that, from this
vantage point, appears
unique in the annals of
the school. It may have
been due to the attitude
prevalent in the nation,
or perhaps it was something within the
walls of the school.
I can't explain it; I
1945 lHE VAST MAJORITY
just know it's there.
THE SC HOOL's STUDENTS
A look through
WERE IN UNI~ORM.
their 1945 yearbook
shows the majority
of students in uniform. Most went directly into active
duty following graduation and picked up formal residencies following stints in the service. Thus, their paths
took a variety of war-influenced turns, both before and
following their training. Some became career military
doctors. Many returned to Buffalo or practiced in

30

l •ttal• nysiein

Spring

2000

small towns fanning out from Western New York
into America's heartland and westward.
Collectively, they have done a tremendous amount
for the school. Some served on the admissions committee, as voluntary faculty members, and as mentors
for students and residents. Others are generous with
their resources, establishing endowments, supporting
scholarships and the school's general fund (many of
their names are in this year's Honor Roll, which
follows). As a tribute to them and to the interweaving
of their lives with World War II, we are working with
volunteers to compile a memory book, for them, for
the school, for those of us enriched by their stories.
Every five years, like clockwork, they reunite in
Buffalo to exchange stories and catch up on each
other's lives. With each passing cycle, the group gets a
bit smaller. Since their 50th anniversary, a hearty core
has met every fall "in case they didn't all make it to
their 55th." I have a feeling they will extend these
annual conclaves as long as there are volunteers to
handle the details.
In addition to my ruminations on the Class of 1945,
what did I learn from my visit to the USS Arizona? That
war really is hell. That understanding that particular
war simply is not possible for those of us born in its
wake. That most people seem to feel genuine sorrow
for the inhumanity of it all, when seen from nearly 60
years' perspective. (Flowers sent to mark the anniversary were from groups like the Japanese-American
Friendship Association, and most of the visitors on my
early-morning sojourn spoke Japanese.)
So, I come down on the side of Anne Frank, believing both that most people are good at heart,
and also that we need to find better ways to resolve
our differences. A war worse than "The Big One" is
too awful to contemplate. Or, as our friends in the Class
of 1945 would attest, it's better to bind up wounds
than to inflict them.
Lyn Corder is associate dean and director of develoment.
If you would like a copy of the 1945 reunion booklet, call
the Development Office toll free, at 1-877-826-3246, or
E-mail Lyn at ljcorder@buffalo.edu.

�the

Lifetime Members
When cumulative contributions reach
$50,000 or an irrevocable deferred gift is
completed for $100,000 or more, a couple or
individual is granted lifetime membership in
the James Platt White Society. Combinations
of outright and deferred gifts in appropriate
proportions may also be the basis of lifetime
membership. Names of Founders-Lifetime
Members-are repeated in an annual
category in any year that they make a new
gift to the school.

ntal in founding UB's medical school in 1846.
F nde s' c· le

Dr. Joseph Chazan '60 and
Mrs. Helene Chazan

Dr. Kenneth M. AHord '37
and Mrs. Joan W. AHord

Buffalo, NY
Williamsville, NY

primarily physicians and attorneys,
envisioned a school to train students for service to the
community. The society's Founders help to actualize
that vision by providing a generous base of support
for programs and activities that enrich the academic
environment and enhance medical training.

Dr. Williard Bernhoft '35
and Mrs. Clarice Bemhoft

Snyder, NY

Dr. Kenneth H. Eckhert '35*
and Mrs. Majorie Eckhert

Buffalo, NY
Ms. Rose Ellerbrock

Dr. Willard Boardman ' 44
and Mrs. Jean Boardman

'48
Winter Park, FL

Amherst, NY
Dr. George M. Ellis '45 and
Mrs. Kelly Ellis

Connersville, IN

Dr. William Chardack

Gulfstream, FL

Spring

Mr. DuVal Cravens and
Mrs. Annette Cravens

Buffalo, NY

Mrs. June M. Alker

DB's Founders,

Providence, RI

Mrs. Grant Fisher

Lakeview, NY

2000

1111a11 Pkysiciu

31

�DEVELOPMENT

fOUNDERS CIRCLE CO!"T·o

Mrs. Catherine Fix

Martinsburg, WV
Dr. Thomas F. Frawley '44
and Mrs. Marigrace Frawley

Chesterfield, MO
Mrs. Christian Gretschel
Genner

Potomac, MD
Mr. John Goodwin

Williamsville, NY
Dr. Pasquale A. Greco '41
and Mrs. Joan Greco

Buffalo, N Y
Dr. Glen E. Gresham and
Mrs. Phyllis K. Gresham

Snyder, NY
Dr. Thomas J. Guttuso '60
and Mrs. Barbara L. Guttuso

East Amherst, NY
Dr. Eugene J. Hanavan Jr.
'41

Buffalo, NY
Mrs. Morris Lamer

New York, NY
Dr. Eugene R. and Mrs. June
A. Mindell

Buffalo, NY
Dr. Richard J. Nagel '53
and Mrs. Forence Nagel

E

W

S

Annual Memberships

Chairs' Circle

Dr. and Mrs. Paul H.
Wierzbieniec '74

Scholars' Circle

Annual memberships, in
the appropriate circle,
are granted for one year,
beginning January 1, for
gifts received during the
prior calendar year. The
roster of the James Platt
White Society "Class of
1999" follows.

Just as a department chair
leads a program, donors
of leadersh ip gifts in
this range of $10,000
to $24,999 are given
special recognition.

Amherst, NY

One strength of an outstanding institution is
the caliber of students
who study there. Scholars in the James Platt
White Society h ave
made gifts to the school
totaling $1,000 to $2,499
during the past year.
Those marked with (**)
are young scholars,
graduates of the last decade, who qualify with
gifts of $500 to $999.

Dr. Hilliard Jason '61

Boulder, CO
Mr. and Mrs. Wilson
Greatbatch

Dean'sCircle

Akron, NY

The dean is the school's
leader. Every leader depends on a small circle
of associates who help
bring the organization's
vision into reality.
Individuals or couples
qualify as members in
the Dean's Circle with
generous
gifts
of
$25,000 or more during the calendar year.

Orchard Park, NY
Dr. Richard B. Narins '63
and Mrs. Ellen B. Narins

Dr. Willard H. Boardman
'44

East Aurora, NY

Winter Park, FL

Dr. Albert C. Rekate '40
and Mrs. Linda Rekate '71

Max Doubrava Jr., M.D. '59

Hilton H ead, N C

Anonymous

Las Vegas, NV

Philip D. Morey M.D. '62

Williamsville, NY

Dr. Syeda Fazila Zafar
and Dr. lsmaial Zafar

East Amherst, NY

Fellows' Circle
Fellows in the school are
recognized for the added
depth they bring to postgraduate study. Within
the society, Fellows are
honored for gifts that
total $2,500 to $4,999.

Dr. Maria Naples Sarno '34

Syracuse, NY
Marie Rose Sarno

Syracuse, NY

Dr. Charles A. Baud a '42

Boynton Beach, FL
Mr. Sheldon M. Berlow

Buffalo, NY

Buffalo, NY

Professors' Circle

Dr. and Mrs. Harold Brody '61
Getzville, NY

Dr. Kenneth Z. AHshuler '52
and Mrs. Ruth AHshuler

A strong faculty is central to a great university.
Likewise, central to the
future of our school is
the dedication of a cadre
of supporte rs whose
annual gifts ra nge from
$5,000 to $9,999.

Dr. Melvin M. Brothman '58

Dallas, TX

Snyder, NY

Darcy Steinhart Amiel
and Jack J. Amiel

Dr. Allen Barnett '65

Pine Brook, NJ

Dr. Elizabeth P. Olmsted
Ross'39

Dr. Janet Sung and
Mr. John Sung

Dr. Charles D. Bauer '46,
and Mrs. Mary A. Bauer

Buffalo, NY

Clarence, NY

Williamsville, NY

Dr. and Mrs. Robert J.
Gillespie

Buffalo, NY

Caledonia, NY
Dr. Philip S. Anson '79

Mr. Arthur H. Judelsohn

Scarborough, ME

Buffalo, NY

Dr. J. Bradley Aust Jr. '49

Dr. Hak J. Ko

San Antonio, TX

Buffalo, NY

Dr. George R. Baeumler '59

Dr. Susan V. Mcleer

Kenmore, NY

Buffalo, NY

Dr. George Bancroft '81 and
Mrs. Susan Bancroft '79

Dr. Richard B. Narins '63
and Mrs. Ellen B. Narins

East Aurora, NY

Dr. Dan Miller '48

Scarsdale, NY

Dr. Claudia D. Fosket '85
and Dr. Robert J. Smolinski
'83

Dr. John C. Newman

Lewiston, NY

Dr. John Parker ' 57
and Mrs. Dorris Parker

Orchard Park, NY

Dr. Charles S. Tirone '63
and Mrs. Anne Tirone '94

Latrobe, PA

Williamsville, NY

Dr. Edward D. Simmons Jr.

Dr. Salvador M. Udagawa

Dr. Phillip B. Wels '41
and Mrs. Elayne Wels

Lakeview, NY

Buffalo, NY

Dr. and Mrs. James J.
White Jr. '69

*deceased

Dr. Nancy H. Nielsen '76

Orchard Park, NY

Buffalo, NY
Dr. Robert G. Smith '49

32

l1ff al o Hys ici an

Sp r i n g

20 00

Drs. Elizabeth and Kevin
Barlog'82

Amherst, NY
Dr. Jared C. Bartow Sr. '66
and Mrs. Barbara Bartow '64

Grand Island, NY
Dr. Paul D. Barry '71

Bethesda, MD
Dr. Ralph T. Behling '43

San Mateo, CA

Dr. Irving Sterman '64

Dr. Richard A. Berkson '72
and Mrs. Andrea Berkson

Boynton Beach, FL

THE CALIBER OF STUDENTS WHO STUDY THERE.

Hamburg, NY

Savannah, GA
and Mrs. Gail Sterman

ONE STRENGTH OF AN OUTSTANDI, G INSTITUTION I S

Dr. WilliamS. Andaloro '45

Bradford, PA

Williamsville, NY

Clarence, NY

Encino, CA

Dr. Anita J. Herbert '63

Miss Thelma Sanes

Dr. Janet and Mr. John Sung

Dr. Kenneth Alford '37
and Mrs. Joan Alford

Rancho Palos Verdes, CA

Mr. Haskell Stovroff

Dr. and Mrs. Michael E.
Bernardino

Buffalo, NY

Buffalo, NY

Mr. James I. Stovroff

Dr. Joel M. Bernstein '75

Buffalo, NY

Williamsville, NY

�EVERY LEADER DEPENDS ON A SMALL CIRCLE OF ASSOC I ATES WHO
HELP BRI 'G THE ORGANIZATION'S VISION INTO REALITY.

Dr. Kathleen O'leary '88 and
Mr. Michael J. Collins '90

Dr. Susan Fischbeck '82
and Dr. Patrick Hurley '82

Buffalo, NY

East Concord, NY

Dr. Suzanne F. Bradley '81

Dr. Mark R. Comaratta '85
and Mrs. Kathleen
Comaratta

Whitmore Lake, MI

East Amherst, NY

Dr. Theodore S. Bistany '60

Buffalo, NY
Dr. Dennis l. Bordan '70

Port Washington, NY

Dr. Martin Brecher '72
and Mrs. Geri Brecher

Dr. Bernice S. ComfortTyran '58

Amherst, NY

Los Altos, CA

Dr. James B. Bronk '81
and Mrs. Suzanne Bronk

Napa, CA

Dr. linda J. Corder

Buffalo, NY

Dr. August A. Bruno Sr. '51

Dr. James J. Creighton Jr.
'79

Amherst, NY

Indianapolis, IN

Clarence, NY
Dr. Edwin J. Manning '61

Dr. Jack C. Fisher '62

Dr. Herbert E. Joyce '45
and Mrs. Ruth Joyce

La Jolla, CA

Lockport, NY

Dr. Thomas D. Aanagan '65
and Mrs. Grace Flanagan '60

Dr. Wendy Kaiser '85 and
Dr. Roger E. Kaiser Jr. '79

Williamsville, NY

Clarence, NY

Dr. Claudia D. Fosket '85 and
Dr. Robert J. Smolinski '83
Orchard Park, NY

Dr. Kyoichi Kano

Williamsville, NY

Tokyo, Japan

Dr. Merrilll. Miller '71

Dr. Genievieve Kanski '58
and Dr. James R. Kanski '60

Coram, NY

Eggertsville, NY
Dr. Reiji Kasukawa

Ann Arbor, MI

Williamsville, NY

Fukushima, Japan
Dr. Kenneth Kim '65
and Mrs. Susan Kim

Dr. Eugene l. Gaier

Buffalo, NY

Dr. Daniel E. Curtin '47
and Mrs. Elaine Curtin

Dr. Penny A. Gardner '69

Mr. Michael T. Bukowski

Orchard Park, NY

Los Altos, CA

Dr. David R. Dantzker '67
and Sherrye Dantzker

Dr. Ronald F. Garvey '53

Roslyn, NY

Dr. lawrence Golden '46
and Mrs. Nancy Golden '48

Dr. William M. Burleigh '67

Rancho Mirage, CA
Dr. Jennifer l. Cadiz '87

Mechanicsburg, PA
Drs. Virginia and Evan
Calkins

Dr. Roberta Dayer '72
and Dr. RogerS. Dayer '60

Williamsville, NY

Tyler, TX

Eggertsville, NY

Buffalo, NY

Dr. Michael Goldhamer '64

Dr. Philip C. Dennen '49

San Diego, CA

Southbury, CT

Dr. and Mrs. Glen E.
Gresham

Dr. Gerard J. Diesfeld '60

Arcade, NY

Williamsville, NY

Hambu rg, NY

Dr. Frederick R. Downs '70

Dr. Kim Griswold '94**

Dr. David T. Carboy '63
and Mrs. Jacqueline Carboy

Attica, NY

Buffalo, NY

Ronald I. Dozoretz, M.D. '62

Lincroft, NJ

Washington, DC

Dr. Robert T. Guelcher '60
and Mrs. Elizabeth Guelcher

Dr. Joseph G. Cardamone
'65 and Mrs. Susan
Cardamone

Mrs. Ruth H. Dugan '65

Eden, NY

Dr. Melvin B. Oyster '52

Dr. Nicholas C. Carosella '54
and Mrs. Mary Carosella

Appleton, NY

Hamburg, NY
Niagara Falls, NY
Dr. Robert Einhorn '72

North Brunswick, NJ

Erie, PA
Mrs. Gilda l. Hansen '44

Williamsville, NY
Dr. John H. Hedger '75
and Mrs. Sandra Hedger

Salisbury, MD

Dr. Yung C. Chan '73

Dr. George M. Erickson '49

Dr. and Mrs. Reid R. Heffner
Jr.

Draper, VA

Deland, FL

Buffalo, NY

Dr. Norman Chassin '45
and Mrs. Charlotte Chassin

Buffalo, NY
Dr. Yong Baek Chi

Lockport, NY
Dr. Prem K. Chopra

West Seneca, NY
Dr. and Mrs. Charles KwokChi Chow

Dr. Joseph M. Failla '82

Dr. William J. Hewett '61

Bloomfield Hills, MI

West Hartford, CT

Dr. Domonic F. Falsetti '58

Dr. Fredric M. Hirsh '73
and Mrs. Donna Hirsch '75

Lewiston, NY
Dr. and Mrs. leon E. Farhi

Williamsville, NY

Dr. Maynard H. Mires Jr. '46

Georgetown, DE
Dr. Joseph F. Monte '59

Clinton, NY

Buffalo, NY

Dr. Robert A. Klocke '62
and Mrs. Barbara Klocke

Williamsville, NY

Dr. John F. Montroy '39
and Mrs. Catherine Montroy

Bella Vista, AR

Dr. Richard Kozak '94**

Eugene, OR
Dr. Daniel C. Kozera '59
and Mrs. Delphine Kozera

Lackawanna, NY

Dr. Beth Moscato '96
and Dr. John A. Moscato '68

Orchard Park, NY
Dr. John D. Mountain '33

Manhasset, NY

Drs. Marie Kunz '58
and Joseph l. Kunz '56

Lockport, NY

Dr. Arthur W. Mruczek Sr.
'73

Medina, NY

Dr. Weerachai ladakom '91

Bangkok, Thailand

Dr. Richard l. Munk '71

Sylvania, OH

Dr. Andre D. lascari '60

Poestenkill, NY

Dr. Masao Nakandakari '55

Honolulu, HI

Dr. Thomas J. lawley '72

Atlanta, GA

Dr. Tomoe Nishimaki

Fukushima, japan

Dr. Jack lemann Jr. '54
and Mrs. Mary MacDonaldlemann

Dr. Thomas P. O'Connor '67

East Amherst, NY

New Orleans, LA

Dr. James M. Orr '53

Dr. Eugene V. leslie '51
and Mrs. Faith leslie

Dr. Marvin G. Osofsky '59

Gallipolis, OH

Williamsville, NY

Nanuet, NY

Dr. laurence M. lesser '70

Dr. Margaret Paroski '80

Atlanta, GA

Buffalo, NY

Dr. Harold J. levy '46
and Mrs. Arlene levy

Drs. Jacqueline Paroski '49
and Paul A. Paroski DDS '45

Amherst, NY

North Tonawanda, NY

Eggertsville, NY

Dr. John M. Hodson '56

Mr. Kevin Feor '80 and
Mrs. Elizabeth Feor '78

Williamsville, NY

Alice Jo Lichtman '58 and
Marshall A. Lichtman, M.D.
'60

Mr. Harold Housler

Rochester, NY

Webster, NY

Rochester, NY

Dr. Hing-Har lo '74

Snyder, NY

Hong Kong

Dr. Amy Ferry '94**

Robert M. Jaeger, M.D. '47

Blacksburg, VA

Bethlehem, PA

Allentown, PA

Dr. and Mrs. Gerald l. Logue

Dr. Carlos R. Jaen '89**

Williamsville, NY

Dr. Michael E. Cohen '61
and Mrs. Joan Cohen

Dr. Helen Marie Findlay '77
and Dr. Albert Schlisserman
'77

Buffalo, NY

Williamsville, NY

Eggertsville, NY

Dr. Thomas A. Lombardo Jr.
'73 and Mrs. Donna
Lombardo

Lexington, MA

East Aurora, NY

Spring

Dr. Robert J. Patterson 'SO
and Mrs. Patricia Patterson
'48
Dr. Norman l. Paul '48

Dr. Eugene E. Cisek

Buffalo, NY

Hamilton, NY

Dr. Neal W. Fuhr '52

Dr. Julia Cullen '49

Eggertsville, NY

Buffalo, NY
Dr. Kaaren Metcalf '78
and Dr. Harry l. MetcaH '60

Dr. and Mrs. David P.
Mind ell

Buffalo, NY

Dr. Stanley l. Bukowski '81
and Mrs. Romana Bukowski

Buffalo, NY
Dr. John Marzo

Dr. Andrew J. Francis '84

Mount Dora, FL

Washington, DC

Dr. Frank A. luzi '88

La Jolla, CA

Dr. Paul T. Buerger '49
Ms. Mary J. Bukowski Schutz

Irene and Frank Jellinek '40

2000

Dr. Clayton A. Peimer
and Mrs. Susan Peimer

Eggertsville, NY
Mr. Edwin Polokoff

Boca Raton, FL

laffa l1 Physician

33

�D

E

V

E

~---------

SCHOLARS' CIRCLE, CONT'D

Dr. Charles W. Pruet

Williamsville, NY

L

0

P

M

E

Dr. Hiroshi Yoshida

Fukushima, japan

Dr. Roy E. Seibel Sr. '39
and Mrs. Ruth Seibel

Dr. Wayne C. Templer '45

Dr. Gregory E. Young '77
and Mrs. Diane Young

Dr. Molly R. Seidenberg '53
Dr. Arthur M. Seigel '70

Guilford, CT

Dr. Bert W. Rappole '66
and Mrs. Mary Helen
Rappole '97

Dr. Elizabeth G. Serrage '64

jamestown, NY

Mr. Eugene M. Setel

Boca Raton, FL

Buffalo, NY
Dr. Richard R. Romanowski
'58

Cape Elizabeth, ME
Buffalo, NY

Corning, NY
Dr. Henry A. Thiede '49

Pittsford, NY
Dr. James C. Tibbetts '64

Sturgeon Bay, WI
Dr. George Toufexis '76

Williamsville, NY
Dr. Bradley T. Truax '74

Lewiston, NY

Dr. Edward Shanbrom '51
and Mrs. Helen Shanbrom

Santa Ana, CA
Dr. John T. Sharp '49
and Mrs. Susan Sharp

Lancaster, NY
Dr. Thomas F. Varecka '74

Minneapolis, MN
Dr. Alvin Volkman '51

Holmes Beach, FL

Greenville, NC

Dr. John B. Sheffer '47

Dr. Richard D. Wasson '58
and Mrs. Janet Wasson

Williamsville, NY

Dr. Charles H. Rosenberg '44
Stamford, CT

Dr. Peter E. Shields '79

Williamsville, NY

Dr. Arnold Wax '76

Dr. Elizabeth P. Olmsted
Ross'39

Dr. Timothy S. Sievenpiper
'68 and Mrs. Karen
Sievenpiper '66

Dr. Pierce Weinstein '49

Dr. Jeffrey S. Ross '70

Holland, NY
Dr. Wende W. Young '61

Canandaigua, NY
Dr. Franklin Zeplowitz '58
and Mrs. Piera Zeplowitz

Buffalo, NY
Dr. David Ziegler '64 and
Mrs. Susan Ziegler '61

Walnut Creek, CA

Mr. James J. Trzaska

Buffalo, NY

Buffalo, NY

East Aurora, NY

Holiday, FL

Special Members
A few individuals and
coup les were gra n ted multiyear memberships based on generous
gifts made between
1989-1993.

Henderson, NV
West Palm Beach, FL
Drs. Charlotte Weiss '52
and Dr. Hyman Weiss '52

Lebanon Springs, NY

Edward H. Simmons, M.D.

Mr. James J. Rosso '76
and Mrs. Cheryl Rosso

Williamsville, NY

Highland Park, Nj

Dr. James A. Smith '74

Dr. Gary J. Wilcox '73

Buffalo, NY

Orchard Park, NY

Carlsbad, CA

Dr. Albert G. Rowe '46

Dr. Albert Somit

Dr. Charles E. Wiles '45

Tonawanda, NY

Aurora, Co
Dr. David W. Butsch

Montpelier, VT
Dr. John l. Butsch

Buffalo, NY
Dr. Marvin Z. Kurian '64
and Mrs. Eleanor Kurian

Carbondale, JL

Orlando, FL

Dr. John J. Squadrito '39

Dr. Richard G. Williams '80

New York, NY

Sarasota, FL

Clearfield, PA

Buffalo, NY

Dr. Pina Sanelli '94**

Dr. David D. Stahl '79

Mr. Ralph C. Wilson Jr.

M edina, NY

Orchard Park, NY

Mrs. Marvin (Helen) Winer

Boston, MA

Dr. William C. Sternfeld '71

Dr. Stuart Alan Wolman '74

Sylvania, OH

Beverly Hills, CA

Snyder, NY

Dr. louise M. Stomierowski
'74

Dr. and Mrs. John R. Wright

Dr. Stephen C. Scheiber '64
and Ms. Mary Ann Scheiber

Garrett Park, MD

Glenview, IL
Dr. James N. Schmitt '52

Kenmore, NY

•• Clln lllrcll

•• ..,.. . . . . . '%1

.....
...........
........

....... s.

Williamsville, NY
Dr. John Naughton

Sarasota, FL

We have made
every effort to en
ure accuracy tn
these hsts If ou
ha e questio or
corrections, please
call Mary Glenn,
toll free at

Williamsville, NY

Dr. Michael A. Sullivan '53

Williamsville, NY
Dr. lin-lan Tang '84

Warren, N]

Dr. Max A. Schneider ' 49

U B's

Orange, CA
Robert N. Schnitzler, M.D.
'65

f OUNDERS, PRIMARILY PHYSICIANS AND ATTORNEYS, ENVISIONED

A SCHOOL TO TRAIN STUDENTS FOR SERVICE TO THE COMMU, 'ITY.

San Antonio, TX
Dr. Adolphe J. Schoepflin '45

Ada, OK
Dr. David S. Schreiber '69

Westwood, MA
Dr. Joseph I.SchuHz'57

San Pedro, CA

l 1 1f a lo Hys ieia n

The following indi
viduals left gen
erous bequests or
made arrangements
for the school to
recetve gtfts from
testamentary trusts
Gtfts from those
listed were received
dunng 1999.

. . . . . . . . '15

Ms. Janet Butsch

Dr. Edwin A. Salsitz '72

Dr. Arthur J. Schaefer '47
and Mrs. Elizabeth Ann
Schaefer

34

w s

Columbus, OH

Rochester, NY

Dr. Frank T. Riforgiato '39
and Mrs. Mary Cecina
Riforgiato '37

E

Dr. Michael Taxier '75

Amherst, NY

Dr. Frederic D. Regan '45

N

Dr. Fred S. Schwarz '46

Eggertsville, NY

Fairview Park, OH

T

Buffalo, NY

Dr. Kenneth J. Raczka '72
and Mrs. Rita Raczka
Dr. John Y. Ranchoff '52

N

S prin g

2 000

�Dear Fellow Alumni,
NOW! R SUCCESSFUL S PRING C LINICAL D AY has recently come and gone. For those of
you who missed this event-organized by Colleen A. Matti more, MD '91, and featuring the
theme of "Children's Health"-be sure to look for coverage of it in the summer issue of
Buffalo Physician.

Prior to Spring Clinical Day, the Medical Alumni Association Board met and chose the
following four alumni from reunion classes to receive achievement awards at Spring Clinical
Day: Richard H. Alder, MD '45; D. Jackson Coleman, MD '60; N. Lynn Eckhert,
PhD, MD '70; and Ani! B. Mukherjee, PhD/MD '75.
The board also met to discuss nominations for the Berkson Award, which is
given to the outstanding teacher among our faculty, and approved nominations
of Robert Kalb, MD, and Corstiaan Brass, MD, to receive this year's honor.
In addition to Spring Clinical Day, I am pleased to report that this year's
Medical Alumni Association programs have all been successful. The Physician-Student Mentoring
Program-in which first-year students are paired up with attending physicians in the Buffalo
area-has had enthusiatic reviews from both the students and the physician-mentors. I
encourage any of you in the Western New York area who would like to become involved in the
program to contact the Medical Alumni Association office at the number listed below so that a
student can be paired with you in August.
The Community Physicians Program for first- and second-year students continues to meet
with success, as well. The Alumni Association, under the chairmanship of Anthony Markello,
MD '62, organizes speakers for these noontime meetings, which also include lunch for attendees.
On February 2, 2000, Jack Cudmore, MD '62, and Daniel Kozera, MD '59, talked about their
careers in medicine.
For more information about any of these events, or other matters, please feel free to call the
Medical Alumni Association office at (716) 829-2778.

RICHARD L. COLLINS , MD
President, Medical A lumni Association

Spring

2000

luffal e Pb ysici ao

35

�CLASSNOTES

1940s
Samuel Cassara, MD '44,

writes from Rochester,
NY: "I retired in 1997.
I am a board certified
pediatrician and was in
the navy twice. The rest
of the time I spent in
private practice. I have
three children: my
oldest, my daugher,
works in public relations
for a private company;
my son is an oral
surgeon and my youngest is a social worker.
Arthur J. Schaefer, MD '47,

attended the American
Academy of Ophthalmology's annual meeting in Orlando, FL,
where he gave a threehour course on the
surgical correction of
malpositions of the eyelids. The meeting was
held in conjunction with
the PanAmerican Society
of Ophthalmology and
was attended by over
25,000 ophthalmologists
from the United States
and around the world.

1950s
Richard Lyons, MD '50,

writes: "I retired july 1,
1999, after 36 years of
practice in anesthesiology; assistant clinical
professor of anesthesiology at the University of
Illinois; director of anesthesiology at Ravenwood
Hospital Medical Center
in Chicago, IL. Also retired from sailing, skiing
and SCUBA. Widowed

36

l 11fala H ysieian

since September 1998.
Maintain homes in
Evanston, IL, and
Holmes Beach, FL.
Looking forward to our
50th reunion."
Ernest H. Meese, MD '54,

received the American
Cancer Society's (ACS)
prestigious National St.
George Medal in November 1999 at the Ohio
Division's annual state
meeting in Columbus,
OH. The St. George
Medal is presented
annually to an outstanding division volunteer.
Meese,
who
practices
cardiathoracic
surgery
in Cincinnati, has been a dedicated volunteer for the
ACS for 36 years and has
served as president of
the board of trustees for
both the local Hamilton
County Unit and the
Ohio Division. He has
also given many lectures
in support of antismoking ordinance
efforts and has seen the
positive results of the
ACS's work in his
region. Currently,
Meese serves as a
lifetime member of
the Hamilton County
Unit Board of Trustees
and as chair of the
Tobacco Committee.
Philip Brunell, MD '57,

writes: "I retired from
NIH a few months ago

S prin g

2 000

but I am off to England
to Great Ormond Street
Children's Hospital as a
visiting professor for
three months in the
spring. I still go into
work at the NIH occasionally, edit Infectious
Diseases in Children and
serve as secretary of the
World Society for Pediatric Infectious Diseases.
Most of all, I enjoy my
four grandchildren."
E-mail address is:
pbrunell@niaid.nih.gov

Jacob Krieger, MD '59,

Daniel Kozera, MD '59,

Sandra Leininger, MD '59,

Lackawanna, NY,
Obstetrics/Gynecology.
"I have been on the
Board of Health for Erie
County for over 15 years
and have served as
president. Due to heart
disease, I left private
practice of ob-gyn in
1986. Since then, I have
worked parttime at the
Erie County Health
Department as a consultant in ob- gyn. I also
consulted for the NYS
Health Department and
I am past president of
Buffalo Gyn-Ob Society
and past chief of ob-gyn
at Buffalo Mercy and
OLV hospitals."

Danville, CA, Pediatrics.
''I'm healthy and happy!"

Rochester, NY, Anesthesiology. "I was chief of
anesthesia at Genesee
Hospital in Rochester,
NY, from 1969-1977;
chief of anesthesia at
Rochester General
Hospital, Rochester,
NY, 1984-1989; clinical
assistant professor of
anesthesiology at the
University of Rochester
School of Medicine from
1969-present." E-mail is:
j mdkrieger@aol.com

Richard Musgnug, MD '59,

Medford Lakes, NJ,
Dermatology. "I have
learned over the years, as
I am sure you all have
too, life is too short and
unpredictable to waste
on things that don't have
any real meaning in your
life. If you can contribute something to a meeting, a committee, a
board, etc., do it; if not,
move on." E-mail is:
Rcmus@aol.com

E-mai

1960s
Roberta Gilbert, MD '62,

writes: "Just published
Connecting with Our
Children, Guiding Principles for Parents in a
Troubled World. Wiley,
NY, publishers."
Robert W. Hamilton, MD '63,

writes, "I was promoted
to Professor Emeritus
of medicine at the Medical College of Ohio on
January 1, 2000. I have
retired from the practice
of medicine, but still
teach parttime. I
remain active in my
church and with the
Ohio Chapter of the
American College of
Physicians as vice president of the chapter. I am
also learning to play the
Great Highland bagpipes. E- mail address is:
rhamilton@core.com
Walter Ceranski, MD '64,

Phoenix, AZ, Family
Practice. "I became a
grandfather six months
ago." E-mail address is:
72772.137@compuserve.com
Joseph DiPoala Sr, MD '64,

Rochester, NY, Internal
Medicine. "I am medical
director and owner of
the Doctor's Wellness
Weight Loss Center to
assist patients in achieving better health, physical fitness and weight
loss. Plus rehabilitation
exercise for elderly and
those with osteoarthritis." E- mail address is:
)dipoalasr@pol.net

�__,

!"'}'

development and Medi·
caid managed care, he

Thomas C. Rosenthal,

practice in the rural

MD '75, professor and

Western New

chair of the Department

York community

Area Health Educa·

of Family Medicine in the

of Perry. Over

tion Center, which
he directs. For his

also led efforts to create
the New York State

thalmology. It's still
new and exciting and
one of the most fun
things in my life, along
with hiking and
kayaking and learning
other 'new' things."

University at Buffalo

the next eight

School of Medicine and

years, he re-

ongoing efforts in

Irving Sterman, MD '64,

Biomedical Sciences, has

cruited and built

the field of rural

been named editor of

the practice into

health services, he

The Journal of Rural

a stable group

was presented with

Health, the peer-reviewed

model.

Boynton Beach, FL. "I
was widowed in 1993
and remarried in 1995
and moved to FL. I am
now working parttime
doing disability evaluations, mostly for
worker compensation
cases in Syracuse, Y.
I am enjoying traveling." E-mail address is:
Turkyii@aol.com

publication of the

Rosenthal returned to

National Rural Health

his alma mater in 1986,

Association INRHAJ.

establishing the Office of

A longtime contributor
to the journal, Rosenthal

the NRHA's Distinguished
Educator Award in 1992.
Rosenthal plans to
broaden the journal's

Rural Health at UB and

audience and impact by

leading the New York

expanding its traditional
focus on health-services

has served on the

Rural Health Research

publication's editorial

Center. Committed to

research to include more

board since 1997. His

improving health care in

articles on clinical issues

interest in rural health

underserved rural areas

and social issues of rural

began in the late 1970s,

through research into

health.

when he opened a solo

such issues as health
professional workforce

Michael Feinstein, MD '64,

Scottsdale, AZ. "I retired
on July 31, 1998, from
my hematology-oncology practice on Long
Island after 26 years. I
am working parttime in
a consultation practice
in hematology-oncology
in Phoenix." E-mail is:
linmic@msn.com
John Hazeltine, MD '64,

Brainerd, MN, Otolaryngology. "I retired in
October 1998. We are
planning to live in Jack-

sonville, OR, and will
move this summer,
nearer to our children in
San Francisco. Retirement is terrific; I should
have done it sooner."
Stephen C. Scheiber, MD '64,

writes from Deerfield, IL:
"I am beginning
my 15th
year as
the executive vice
president
of the American Board of
Psychiatry and Neurology and I am currently

- MARY BETH SP I NA

for the Advancement of
Psychiatry and the treasurer for the American
College of Psychiatrists.
I continue to be active
on a number of committees of the American
Board of Medical
Specialties and participate in national meetings of many of the
psychiatry and neurology specialty and subspecialty organizations."
Elizabeth Serrage, MD '64,

Cape Elizabeth, ME,
Ophthalmology. "I still
love practicing medicine

C1aS'SiiOteS

SPRING

2000

J. Michael Taylor, MD '64,

Portland, ME. "I have
developed a four-person
dermatology practice in
Portland, ME. I encounter Liz (Goering) and
John Serrage regularly,
both professionally and
socially." E-mail: m.and.
w.taylor@worldnet.att.net
James Tibbetts, MD "64,

Neurological Surgery.
"We retired December
31, 1997, and are enjoying it and each other."
Shorepeace@dcwis.com
David Ziegler, MD '64,

Walnut Creek, CA, Neurology. ''I'm retired and
spend March in Phoenix- spring training
(baseball)." E-mail is:
Davidz@pc-systems. net
Stuart H. Shapiro, MD '68.

After graduation and
board certification in
radiology, nuclear medi-

Spring

2000

cine, and public health,
Shapiro turned his attention to the interface
of politics, business and
medicine. After staffing
the U.S. Senate Health
Subcommittee Committee, he became Health
Commissioner for the
City of Philadelphia and
joined the faculty at
Wharton School of Business at the University of
Pennsylvania.
He then
moved into
the private

health-care financing
at a large bank, then
became senior vice president of a multinational
nutrition company.
Later he was named
CEO of a publicly traded
company that provides
health care to prisoners
across America. In 1997
he was recruited to be
CEO of the President's
Summit for America's
Future with Presidents
Clinton and Bush as active honorary chair and
General [Colin] Powell
as the chair. Shapiro
continues to work with
General Powell and to
do private investing and
consulting for for-profit
and not-for-profit
businesses. He feels he
certainly may have the
youngest children of
anyone in the class- a
daughter four and a son
11 months. E-mail'- - - address is:
shapirostu@aol.com

lu lf1l1 Hysieiu

37

�CLASSNOTES

James Cavalieri, MD '69,

Williamsville, NY,
Pediatrics. "I am past
president of the Buffalo
Pediatric Society; past
member of the board of
trustees for Children's
Hospital; and past board
member of Independent
Practice Associates. I am
a founding member of
Community Pediatric
Associates ofWNY LLC.
1994 Pediatrician of the
Year." E-mail address is:
Jimkatec@aol.com
John Fisk, MD '69,

Springfield, IL. "I am
professor of surgery at
Southern Illinois University School of Medicine." E-mail address is:
Jfisk@siumed.edu
William Major Jr, MD '69,

Orchard Park, NY,
Thoracic Surgery. "I am
executive director, IPA/
WNY, January 1999current." E-mail is:
Wmajor@buf.adelphia.net

William E. Stempsey, MD
'78, SJ, has recently

published a book titled
Disease and Diagnosis,
Value-Dependent Realism. Stempsey, a member of the Jesuit Community,
currently
is an
assistant
professor
in the Department of
Philosophy at the

FACP, FAC, writes: "I
retired from active solo
practice of medicineinternal medicine and
cardiology- in March
1999, not by choice but
due to health reasons. In

College of Holy Cross in
Worcester, MA. In 1988,
ten years after earning
his medical degree at
UB, Stempsey completed
a master of arts degree in
philosophy at Loyola
University Chicago,
after which he earned a
master of divinity degree
from the Jesuit School
of Theology at the Uni versity of California at
Berkeley. In 1996, he
completed his doctorate
in philosophy at Georgetown University. The
book's publishers,
Kluwer Academic, state
that Stempsey's book
"will be of interest to

1111111 Hysici11

Sprin g

1970s
Russell P. Massaro, MD '70,

lives in Elmhurst, IL,
and is currently executive vice president for
accreditation operations
at JCAHO.
Ashesh K. Maulik, MD '72,

38

May 1998, I was discovered to have pituitary
macroadenoma. I underwent a craniotomy,
followed by radiation
therapy. Due to weakness and failing vision,
I could not practice.
Moved to Las Vegas,
NV, to be near family.
I miss Western New
York and all the CME
courses in Buffalo."

2 000

philosophers of medicine, value theorists, bioethicists, and physicians"
because it "situates the
practice of diagnosis in a
new vision of how values
permeate the world of
disease and medical
practice." More information on Disease and
Diagnosis can be obtained by calling Kluwer
Academic Publishers at
(781) 871-6600; E-mail:
kluwer@wkap.com
Avery It Ellis, MD '77. PhD '79

has been appointed
physician executive at
the Department of
Veterans Affairs Western
New York Healthcare
System. As clinical head
of the veterans' facility,
Ellis supervises the
operation of both the
Buffalo and Batavia sites,
as well as community
based outpatient clinics
in Jamestown, Dunkirk,
Niagara Falls, Lockport
and Warsaw. Ellis received his undergraduate
degree from Cornell
University and his medi cal degree from UB,
where he also received
his PhD
in physiology. He
completed a
medical
residency
and cardiology fellowship at Stanford University Hospital. In October
1999, he received an
MBA from Duke University. At UB, Ellis is an
associate professor of

medicine and physiology, as well as director of
the Cardiology Fellowship Program. A Fellow
in the American College
of Cardiology, he also
holds membership in the
American Heart Association, the American Society of Echocardiography
and the New York Sate
Cardiologic Society.

of
Andover
[Maryland]
and is
medical
director
of two nursing facilities
in the area and a local
college. He has also been
a mentor to family
practice students
and residents.

-

Terence Chorba, MD '79,

writes: "After working
on infectious disease
issues in Kazakstan and
central Asia for the Centers for Disease Control
for four years, I am now
working in Cote d'Ivoire
[Ivory Coast] as director
of Project Retro-CI, a
collaborative AIDS/TB/
STD research activity of
the Ministry of Health
and the CDC."

1980s
David Bristol, PhD '82,

lives in Ann Arbor, MI,
and is currently director
of biometrics at ParkeDavis Pharmaceutical
Research, where he provides guidance for development of treatment for
cardiovascular diseases.

Wesley L. Hicks, Jr. DDS, MD
'84, FACS, has been ap-

pointed director of the
Fellowship Program in
the Division of Head and
Neck Surgical Oncology/
Plastic and Reconstructive Surgery at Roswell
Park Cancer Institute
(RPCI). In this capacity,
he is responsible for the
national
accreditation and
development
of education and
research
programs at RPCI
through the American
Head and Neck Society.
He will also continue to
serve as associate professor in UB's Department
of Otolaryngology.

Anthony E. Turiano, MD '83,

has been listed in the
Guide to Top Doctors, a
state-by-state listing of
15,000 doctors in 30
specialties nationwide
who are most highly
recommended by their
peers. Turiano is chief
of family practice at
Suburban Health Care

Andrew M. Knoll, MD '84,
FACP, and Maritza
Alvarado, MD '85, write:

"Andrew has received a
chancellor's scholarship at Syracuse
University College of
Law and graduates in
August 2000."

�In Memoriam
Stuan Y. Collins, MD' 40,
died on April 16, 1999.
After being discharged
from the Army Medical
Corp, in 1946, Collins
practiced medicine in
Elmira, NY. Following his
retirement in 1975, he
resided in Tequesta, FL,
with his wife, Marian,
who survives him and
who currently resides at

113 Cool View Drive,

Noma Roberson, PhD '86,

of Amherst, NY,
recently published a
book, titled Year 2000
and Beyond, which
offers information
about the potential
impact of the year 2000;
a checklist for personal
information, housing,
money, supplies, communications, transportation and personal
computers; and spiritual
guidance and devotion.
Roberson is president/
CEO of a
newly
formed
consulting company,
Roberson
Consulting Internationa!, the mission of
which is to provide consultation to universities,

Seneca, SC, 29672-2302.

nity Hospital in

Julian, named

Julian was well known as

Collins is also survived by

Jersey City, NJ,

a diplomate of

a chef and culinary advi·

three children and four

after which he

the American

sor who frequently

grandchildren.

returned to But-

Board of Ob-

cooked in his home for

Peter J. Julian, MD '47,

falo to complete

stetrics and

Dallas restaurant chefs.

his residency

Gynecology in

Besides his wife, Ruth
Gray Julian, he is

a Dallas, TX, obstetrician!

training at Dea-

1954, moved

gynecologist who practiced

coness Hospital

to Dallas with

survived by a son,

in Buffalo from 1951-

in 1951. He then

his family in

nationally-known

1960, died of a heart

entered private

1960 to start

neoexpressionist artist

attack in June 1999 at his

practice on

his own prac-

Peter Julian, of New

Dallas home. He was 74. A

Humboldt Parkway with

tice. He served as a clinical

York, NY; a daughter,

native of Buffalo, Julian

Dr. W. Herbert Burwig, who

professor at the University

Linda Julian Richie of

also completed his under·

had the largest obstetrical

of Texas Southwestern

Dallas; a sister, Mildred

graduate studies at UB.

practice in Buffalo and

Medical Center at Dallas,

Nicholas of PA; and

Following graduation from

developed the city's first

from 1960 to his retirement

a granddaugbter.

medical school, he interned

group practice in obstetrics.

in 1998. In addition to his

at Margaret Hague Mater-

(Burwig died in 1992.)

reputation as a physician,

foundations and
government agencies
that conduct health
research and services
for public education.

Peggy Stager, MD '88,

Dlufowobi Gbadebo, MD '91,

writes: "My husband,
Dick, and I welcomed
our second son, Benjamin, on Superbowl
Sunday, January 31 ,
2000. Dick is certain that
Ben's birthday is a sure
sign that he will be a professional football player!"

writes: "Buffalo Physician
is sure a good way to
keep in touch with
events and developments
within the University at
Buffalo and the affiliated
hospitals. As an alumnus
of the Medical Department, I look forward to
each edition of the
magazine. Although
my practive here in
central Wisconsin is
busy and rewarding,
reading about my
colleagues in Buffalo
makes me homesick."

Anhur Weissman, MD '86,

writes: "I am a general
surgeon at Tri County
Memorial Hospital, in
Gowanda, NY, and have
a busy solo rural practice. I'm fortunate to be
surrounded by excellent
nurses and support staff
and grateful to be alive
and well, working and
enjoying operating and
office practice. Watching my kids grow up
(Katie is 13-going on
35-and Zack is almost
9). Pat and I are planning our 20th anniversary trip to Paris. My
best to all." E-mail is:
arthursurg@aol.com

1990s
Sean Cao, MD '90, was

recently appointed
associate chief, Division
of Transplantation,
Department of Surgery,
at the University of
California at Irvine's
Medical Center. His
address is UCI Medical
Center, Bldg 26, Room
1001, Route 81, Orange,
CA 92868-3298; his
telephone number is
(714) 456-8441.

David J. Rodman, MD '91 ,

writes: "I have received
an appointment in
SUNY at Buffalo's Department of Chemistry
as a research assistant
professor and have
joined the Biophotonics
Institute [see related

S prin g

2000

CD

article on page 20 ]. I will
be working on joint
collaborative projects,
including solid-state
lasers and new drugdelivery systems. "
Rosalind Nolan Sulaiman,
MD '91, writes: "Rosalind

Nolan Sulaiman and
Adel Sulaimen are
pleased to announce the
birth of their second
son, Kyle, last spring.
Big brother, Cass, is
now four."
Daniel Pitterman, MD '92,

writes: "I am an assistant
professor of anesthesiology at Loyola University
Medical Center in Chicago. My wife, Corrine,
and I are expecting our
first child in March."

I~NT I NUEO

ON

PAGE + 0

l affale Pbysician

39

�CLASS

NOTES

BRAZIL REDUX

Do you have a favorite
memory, anecdote or
inspirational moment
that you associate with
your medical education?
How about a favorite
professor, mentor or

classmate you'd like to
tell about?
Buffalo Physician is putting out a call for stories
about your past, which we
will publish in future
issues of the magazine.
Here are some ways you
can submit your story• •.
bp-notes@buffalo.edu

716-645-2313
Editor, Buffalo
Physician, 330 Crofts
Hall, Buffalo, NY 14260.
Be sure to include your
name and a phone number or address where you
can be reached.
Your fellow alumni look
forward to reading about
your storied past!

CONTINUED

FROM

PA GE

13

toxoplasmosis. Again, most of the diagnoses were
based on history and physical exam, and I did learn
how to perform a thorough medical examination
and how to more efficiently use the history and
presentation of the patient. I feel that this experience
raised my skills to a new level and certainly deepened
my appreciation for medicine.

l Day-and Month-To Remember

Joseph M. Kowlaksi, MD '93,

has been appointed to
the medical staff at the
Erie County Medical
Center (ECMC)
Healthcare etwork. An
orthopaedic physician/
surgeon, he will join the
current team of specialists at ECMC's Spine
Center.
Kowalski
earned
his medical degree
summa
cum laude
from UB,
where he also completed
his residency. He then
completed a fellowship
in spine surgery at
Emory University in
Decatur, GA. Prior to
medical school, he
earned a doctor of chiropractic degree from the
National College of Chiropractic in Chicago, IL.
Kowalski is a diplomate
of both the National
Board of Medical Examiners and Chiropractic
Examiners. He is a member of the Alpha Omega
Alpha Honor Medical
Society and the orth
American Spine Society.

l1flal• Hysiciu

Mansour V. Shirbacheh, MD
'93, PhD, writes: "After

obtaining my MD, I
started general surgery
training in Long Island,
NY. However, in 1996, I
decided to leave clinical
training and join plastic
surgery research in Louisville, KY. My research
and many others culminated in the first hand
transplant in the U.S. I
also applied my research
to my PhD dissertation.
I received my PhD in
physiology last May. I
am currently training in
plastic and reconstructive surgery in Louisville
and will graduate in
June 2001."
Carollnn Killian, MD '94,
Thomas Burnette, MD '94,

write: "We are pleased to
announce the birth of our
second daughter, Lauren
Killian Burnette, on November 24, 1999 (7lbs.,
11 oz.). Big sister, Kristen,
is now 19
months
old and is
adjusting
well! Tom
continues
to practice
internal

Spri n g

2000

medicine and Carol
Ann, emergency medicine, in NY.
Catherine (Costello) Skae,
MD '97, writes: "My hus-

band, John, and I
proudly announce the
birth of our daughter,
Anya Bernadette, who
was born on January 21,
2000-9 pounds, 7
ounces. I am a third-year
pediatrics resident at the
Albert Einstein College
of Medicine, Montefiore
Medical Center, Bronx,
NY, where I will be the
pediatrics chief resident
starting in July 2000."
Paul Guttuso, MD '97,

writes: "I will be starting
a fellowship in sports
medicine in July 2000.
My wife, Trinia, an
occupational therapist,
just passed licensure for
certified hand therapy.
We are so proud!"
Paul Rosen, MD '97, writes:

"I will graduate from
Mt. Sinai's Department
of Pediatrics and start a
fellowship in pediatric
rheumatology at
Children's Hospital of
Cincinnati in July 2000."

M

y last day at the hospital is one I will always
remember, as that's when I completed my
most difficult assignment. Weeks earlier, a
professor had asked me if I would be interested in
giving a talk on hepatitis A. He gave me articles to
read, as well as suggestions on what I should cover.
He also recommended that I generate a handout
for the students.
So, on that last day-in front of my classmates,
professors, nurses and hospital administrators! gave a 20-minute presentation in Portuguese.
Although I was anxious about having to present
such technical information in a foreign language,
it went very well. I did have difficulty pronouncing
certain medical words without a strong accent;
however, the audience was responsive and helpful.
After I finished, I realized that I had learned a
lot about myself, my work ethic and my presentation skills. Having overcome such a challenging
situation, I now feel I would be comfortable
speaking in front of any group.
Looking back on my experience in Campos, I
can see that every facet of my education was
enhanced, as I learned a tremendous amount
about medicine- and myself. In short, I feel that
my month in Brazil was a high point in my medical
education, to date, and one that further affirmed
for me that medicine is my career of choice. CD
Michael White is a fourth-year student at the
University at Buffalo School of Medicine and
Biomedical Sciences. This summer he begins residency
training in emergency medicine at Eastern Virginia
Medical School, Sentara General Hospital, in
Norfolk, Virginia.

�HEN DEBORAH A. WHITE, MD '87,
her husband, Christopher, and their
four-year-old son, Adam, were killed
m an automobile accident in February
1999, a number of people at the University at Buffalo School of Medicine and
Biomedical Sciences felt a desire to bring
together alumni, faculty, staff and friends with the
goal of memorializing the Whites. Instrumental in
this effort has been Dr. Gail Willsky, associate
professor of biochemistry, who knew Deborah as a
student and friend and remains close to her family.
As a result of the efforts of Dr. Willsky and others
over the past year, the medical school's Office of
Development has established the Deborah, Christopher and Adam White Memorial Fund. Proceeds
from this fund will support a summer internship for
a first- or second-year medical student at UB who is
interested in pursuing rural medicine as a career.
As many of you know, Deborah was a native of
Western New York and grew up on a dairy farm in
Eden. Three years after earning her medical degree at
UB, she joined a busy internal medicine practice in
Middleport, a town of approximately 2,000 people
several miles west of Medina, where she was on staff
at Medina Memorial Hospital. The same year
Deborah began her practice in Middleport,
Christopher-who earned bachelor's and master's
degrees in biology from UB-chose to give up his
position as a cellular and molecular biologist at
Roswell Park Cancer Institute to become a stay-athome parent.
Today, the White's surviving children, Andrew,
10, and Elizabeth, 7, live with Christopher's sister,
Mrs. Sue White Chiddy, in Elba. Mrs. Chiddy says the
children are doing well and both show an interest in
science. (Andrew says he'd like to be a veterinarian.)

Friends and colleagues who knew of
Deborah's dedication
to rural medicine felt
that an endowment
supporting education
and training in this
area of health care
would be the best way
to honor her life as
a physician.
In the future, a
student whose training is supported through the
memorial fund will be expected to complete a
summer internship in a rural setting, preferably in the
Deborah and
Medina area. In addition to supporting a
rural internship, it is hoped that the fund
Christopher White,
will provide two additional awards: one to a
with Andrew, Adam
student graduating in the biological sciand Elizabeth.
ences, and another to a student graduating
Today, Andrew and
in biochemistry, thereby honoring both
Elizabeth live with
Deborah's and Christopher's accomplishChristopher's
ments in these fields.
sister, Mrs. Susan
For more information about the
Chiddy, in Elba, NY.
Deborah, Christopher and Adam White
Memorial Fund and its support of students interested
in pursuing careers in rural medicine and biological
sciences, please contact Mary Glenn in the medical
school's development office by calling (toll free)
1-877-826-3246; e-mailing glenn@acsu.buffalo.edu;
or writing to: Office of Development, School of
Medicine and Biomedical Sciences, University at
Buffalo, 102 Cary Hall, 3435 Main St., Bldg. 23,
Buffalo, NY 14214-3005.

�We Get Rehab Results!
Our Superior~ Improvement
Vs. National and Northeastetn
Regional Subacute Facilities

Hve Star Care

The McGuire Rehabilitation Centers achieve a 34%
GREATER FIMsM increase vs. the national average for
all admissions.
• Pain Management
Stroke
• Medically Complex
• Orthopedic
• Infections
Cardiac
• Cancer
• Joint Replacement
• Amputee

Our facilities were rated outstanding in the
community with five stars out of five, according to
the Inside Guide to America's Nursing Homes for
long-term care.

0

*****

0

The McGuire
learn. ofExperts
The McGuire Rehabilitation
Centers employ a team of
over 30 licensed Physical and
Occupational Therapists,
specially trained support
staff, and an on-staff
Physiatrist/ Gerontologist.
Together they ensure the
highest level of individualized
medical and restorative care.

Cost Effective!
Transfer

=Inpatient Admissions

I

The McGuire Rehabilitation Centers'
average charge per case is more than 35%
WWER than other facilities in the nation,
according to statistics from The Wall Street
Journal and the American Health Care
Association.

To1let
Transfer

=Inpatient Discharge

I =Outpatient Follow-Up

Our case mix is consistent with the Northeast and national su bacute region. Our

average statistics are: length of stay - 25 days; age - 78; admission FlM score 72.5; discharge FlM score- 97.6; FlM change- 25. 1 points; length of stay
efficiency- 1.40; onset time- 17; discharge disposition- 80% to community. Based
on 12 months ending March 3 1, 1998.

The McGuire Rehabilitation Centers rely on the national
The results are in. The McGuire Rehabilitation Centers have
leading measurement tool for documenting patients'
the clear advantage over other regional facilities based on FIMsM
rehabilitative outcomes. This tool is known as FIMsM©
improvement, discharge to home, and cost effectiveness.
Instrument; Functional Independence Measure, developed ,.,...
Our successful rehab program delivers results
by the UB School of Medicine along with the Center for
~ ~ because of our superior staff, state-of-the-art equipment,
Functional Assessment Research. It's used
and specialized rehab facilities. Choose The
along with the Uniform Data System for
McGuire Rehabilitation Centers for five-star
Medical Rehabilitation (UDSMRsM)
rehabilitation services.
to establish rehab outcomes that
DTT ~JI'T""T""J\T Call l-888-POSTACUTE.
can be measured and calculated .&amp; ~~
~\7~

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Autumn View • Garden Gate • Harris Hill• Northgate

BP 0004-00

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                    <text>�l1ffale

P~ysicial

A SSOC IATE V I C E PRE S I DE

T FO R

U NIVERSI T Y SERVI C E S

Dr. Ca role Smith Petro

Dear Alumni and Friends,

DIRE CTO R O F P U BLI C ATI ONS

Kathryn A. Sawner
EDI TO R

Stephanie A. Unger
~\ RITI '(,,

nn

I·~D 01 Till \( ADF\11(

n

\R

is upon us and both freshme n and

sophomores are in the m idst of fina l examinations. Although the newly created study space

ART DIRE cT 0 RIDE s I G N E R

Alan]. Kegler

is as yet un furnished (the furniture is on order), we have made some makeshift arrangements
for students du ring their finals and for national board preparation. We hope to have this
important student resource fully functional shortly.
On another positive note, we hope to upgrade the computer lab during this next year,
as the present computers are three years old and their warranties are about to expire. The
newer machines (and redistribution of the o lder ones) will be helpful to the new curriculum

A SS I STA N T DE S I GN ER

Lynda Donati
PR O D UCT I O N COO RDIN ATO R

Cynthia Todd - Flick
STATE UN I V ERSIT Y OF NE W

as it begins to u nfold a year from now. Some of the o lder pentium computers will be

YORK AT B u FFALO S c H oOL

relocated to the Standardized Patient Project, which, as many of you know, is a project

OF M E DI C I N E AND

through which Buffalo has taken a leadership role in the development of

BI O M E DI C A L S C IE NCES

Dr. fohn Wright, Dean

modules for the national board, as well as in the development of
E DI TO RIAL B O ARD

standardized testing.
In collaboration with the national board, our own computer group,
under the leadership of Dr. Ray Dannenhoffer, has devised a system to
computerize studen t-"patient" interactions for reporting direct ly to the
board. Using industry standard hardware and software wi th customized
programming scripts, a pilot project was so successful that we have been
asked to provide the computer support for each of the board's present test sites at the
University of California at Irvine, Mercer University, Tulane University, the University of
Massachusetts, East Carolina University, St. Lou is Un iversity and, of course, UB. We will
configure the servers and workstations here and ship them to each of the participating
schools. Our staff will then complete hardware and software installation on site and train
loca l personnel on program operation. Since the standardized patient will soon be part of
national board testing, our school's involvement in the process is something to brag about.
Speaking of"bragging rights," our Mini Medical School has a few of its own. Through
this innovative progra m , Harry Sultz and Alan Reynard have developed a remarkable
community resource. The Mini Medica l School recently received a welcome "shot in the
arm" through a generous gift from Esther and Don Davis. This support will provide muchneeded financial stability as the project branches out in both subject area and community
coverage. We have already been alerted to a need in the Southtowns, and the facu lty are
looking into telemedicine venues in order to reach an even broader community. This, of
course, has implications for a range of programs at UB, includ ingCME and GM E possibilities.
Finally, Dr. john Yeh, from the University of Minnesota, joined the Department of

Dr. Bertram Portin, C hai r
Dr. Martin Brecher
Dr. Haro ld Brody
Dr. Linda f. Corder
Dr. Alan]. Drin nan
Dr. fames Kanski
Dr. Elizabeth O lmste d
Dr. Steph e n Spau lding
Dr. Bradley T. Tru ax
Ms.fennifer Wiler
Dr. Franklin Zeplowitz
TEA C HIN G H O SPITALS

Erie County M edica l Ceuter
Roswell Park Cancer Institute
Vet erans Affairs Western
N ew York Healthcare System
K A U :IDA Hf: A l_ J fl:

Th e Buffalo General Hospital
The Children 's Hospital of Buffalo
Millard Fillmore Gates Hospital
Millard Fillm ore Suburban
Hospital
C ATH OLIC H f. A l TH SY&lt;Tf.\1:

Mercy Health System
Sisters of Charity Hospital
Niagara Falls Mem orial
Medical Center

® TIE STITI IIIYIISITY If lEI Till AT II HALO

Ob-Gyn as chair on May I. He has recruited four new facu lty and is working on a fifth . And
we look forward to the arrival of Dr. Kenneth Blumen thal, from the University of Cincinnati, who will begin leading the Department of Biochemistry around the first of August.
Greetings to you all, and best wishes for a very pleasan t and relaxing summer.
7

(
/

~&lt;/~
R. WRIGHT, MD
Dean, Sch oo l of Medicine and Bio m edica l Scien ces

jOHN

Buffalo Physician is published
quarterly by the State University of
N ew York at Buffalo School of
M ediciue aud Biomedical Sciences
aud the Office of Publications. It is
seut, free of charge, to a/umui,
faculty, students, restdents, aud
frieuds . The staff reserves the rig/It
to edit all copy and submissions
accepted for publication.

T...:l:... University at suffal;rk

-:.=:s

Tiu&gt;State University ofNew

�V 0

L U M E

35,

NUMBER

0
H

Special

2

group helps
first-year
students

14 Match Day
18 Graduation

N

Concussion in sports: new
guidelines call for "time-out"
BY

S.A.

UNGER
MILLER

Wake·up Call
Difficult decisions for
a gifted young athlete
S. A.

BY

UNGER

Carl Lindros, left, father of hockey stars Brett and Eric Lindros, has teamed up with University
at Buffalo professor Barry Willer, PhD, right, to institute back·to·play guidelines following
concussion in amateur sports. The story of their successful international effort begins on page 2.

Baseline Scoring
UB professor's neurocognitive
test used by FL and NHL
BY

S. A .

UNGER

21 Professor

13 New tutorial

A

Safe and Sound

COVER

prospective
students an
in-depth
preview

c

s

eport

PHOTOGRAPHY BY FRANK

8
10

y

Theodore
Bronk
remembered

22 New faculty
23 Nancy Druar
wins Naughton
Award

ILLUSTRATION

BY

WHITNEY

SHERMAN

25 Maxine Hayes
returns to UB
to deliver
Stockton
Kimball lecture

27 Medical Alum ni
Lifetime
Achievement
Awards

29 Reunion classes

traditions begin
today

your classmates
and other UB
alum ni

36 First Minority
Alumn i
Reunion held

40 Medical
Alumn i
Association
officers elected

reception
October 29 in
Chicago

41 Photographs
from Spring
Clinical Day
and Reunion
Weekend
gatherings

�or

ort

by S. I. Unger

Photos by Frank Miller

-Carl
,,

lin~ros

�Due to concussion. Brett Lindros, right, was forced to
withdraw from the National Hockey League in 1996 at the age
of 19. His injuries served as an impetus for his father, Carl
other
young athletes from experiencing what his son-former
professional hockey player Brett Lindros-experienced that
led Carl Lindros four years ago to seek out Barry Willer,
PhD, an expert in traumatic brain injury and a professor of
psychology at the University at Buffalo School of Medicine and
Biomedical Sciences. Since that time- due in large part to
Lindros's inspiration- Wilier has become a highly visible leader
in international efforts to establish return-to-play guidelines
following concussion in amateur sports.
The pivotal event that allied Willer and Lindros in their efforts
to prevent concussions in sports took place in Buffalo on ovember 24, 1995, during a ational Hockey League (NHL) game
between the New York Islanders and the Buffalo Sabres. During
that game, while his father watched from the stands, Brett, a
second-year player with the Islanders, sustained a concussion
that not only changed his life forever but, indirectly, impacted
the world of amateur sports, as well.

Lindros. to work with University at Buffalo professor Barry
"While watching
Willer to develop guidelines aimed at keeping young athletes
the game, I rememout of sporting events for asafe period of time following a
ber seeing Brett check
an opposing player in
concussion. Pictured with Brett is his older brother Eric. of
open ice late in the
the Philadelphia Flyers. who today is fighting his own
first period," Lindros
well·publicized battle with concussion.
recalls. "He wasn't hit
in the head, but the
deceleration from the contact caused him to be concussed."
When Brett didn't come back on the ice at the start of the
second period, Lindros became concerned and went to the
locker room to look for him. There he saw something he says
he will never forget.
" I found Brett sitting alone, trembling. And right away r
could see he wasn't himself," explains Lindros. "He was very
disoriented-one moment he was coherent and the next moment, incoherent; he was fading in and out. l could see that it
was a serious issue."

S 11mm er

2000

Bu ffalo Physician

3

�he next morning, having returned home to Toronto, Lindros went to the public library to discover
what he could about concussions. It was through his research in the weeks that followed
that he first learned about the Ontario Brain Injury Association (OBIA), an organization that
Willer-a native of Canada-has been affiliated with as avolunteer for more than ten years.
"In my search of the literature, I found a lot of current
" He'd go 'in and out,' and there were noticeable changes in his
behavior. He was anxious and jittery-like he had too much
papers on severe traumatic brain injury, but hardly anything
about repeated mild traumatic brain injury, and it's these
caffeine-so he couldn ' t focus on anything for very long."
Over several months, Brett's symptoms gradually abated;
types of injuries-concussions-that are the most preventable," says Lindros. "What I did find about concussions tended
however, in the interim he sought the opinion of three promito be published in the last 10 years, but the theories they
nent neurologists, each of whom recommended that he not play
discussed were often contradictory, and they confused me
hockey again. As a result, on April 15, 1996, at age 19, Brett
because I was looking for clear direction," he adds.
formally announced his withdrawal from the sport.
Despite the dearth of published research on concussions,
Knowing what he now knows about concussions, Lindros is
Lindros did discover startling statistics about the scope of the
thankful that his son was not hurt worse than he was. "Brett's
problem, including the fact that an estimated 30 percent of all
concussion [in November 1995] was his second in an eight-day
youth in the U.S. and Canada will experience a concussion
period. What I realize now is that he was probably playing in a
before they leave high school and that, of these cases, only
concussed mode that night."
about one-fourth will be seen by a physician.
In hindsight, Lindros also realizes that Brett might have been
As long as there is only one minor concussion, the symptoms
playing in a concussed mode earlier in the session, as well.
are, for the most part, reversible, and the brain recovers within
"For example, l remember on one occasion Brett's coach
about five days. However, when there are multiple minor conasked him what he was doing during a shift, and he couldn't
cussions, particularly if these concussions occur
tell him because he couldn't remember.
close in time, the probability of irreversible brain damage
"Clearly, Brett could have been seriously and permanently
rises dramatically.
injured in Buffalo. If he had had a significant direct blow to his
More worrisome still is the fact that if a young athlete is
head that night, there's no telling where he'd be today. There 's
allowed to return to play too soon following a concussion and
no doubt he was playing when he should not have been. "
sustains a second, even minor, blow to the head, he or she
can experience a rare, but lethal, condition called secondimpact syndrome.
On March 12, 1997, the American AcademyofNeurology (AA
The more Lindros learned about concusheld a news conference in New York City for the purpose of
sions in the weeks following Brett's injury,
announcing return-to-play guidelines it had established. In
the more concerned
response to an invitation from the AAN, Brett attended the news
he became for his
son, whose symptoms
were debilitating. "He
ut of this discussion evolved the guidelines that were adopted in 1998, which,
couldn ' t dial a digital
phone, he couldn't
according to Willer. have been worded in such a way that they "not only make sense
read, he couldn't drive,
medically. but are presented in a format that enables mom·the·team·trainer to readily
and what was really
frustrating was that his
understand them-mom, that is, whose occupation may be accounting, not medicine."
symptoms weren't consistent," says Li ndros.

4

Butt a I o Physician

S 11111111 er

20 0 0

�-~

- - - - --

~~--~-------------------~-------------

conference and participated in a panel discussion on the guidelines and their role in attempting to prevent concussion in sports.
Soon after this event, the Lindroses were contacted by the
OBIA and asked if they would lend their support to the
organization's fund-raising efforts, which they agreed to do with
the stipulation that a portion of the proceeds raised go to
disseminating information about the AAN's guidelines.
In response to this request, the president of the OBIA initiated
preliminary discussions with the Canadian Hockey Association
(CHA) in an attempt to get the association to agree to adapt the
AA 's guidelines.
It was when these discussions came to an impasse in the
summer of 1997 that Lindros asked Wilier-whom he had met at
an OBIA event-if he would help get the stalled negotiations
with the CHA back on track.

W

iller agreed to collaborate with Lindros on the project, as
well as on a myriad of other preventive strategies aimed at
keeping young athletes out of sporting events for a safe
period of time following a head injury. On January 1, 1998,
their efforts came to fruition when the CHA formally adopted return-to-play guidelines that had
been painstakingly crafted by Willer with the assistance of John Leddy, MD, a UB associate professor
of clinical orthopaedics and associate director of
the university's Sports Medicine Institute.
Getting the return-to-play guidelines adopted
by the CHA was a very significant step forward,
according to Willer, because "the association
governs all amateur hockey in Canada, which
makes it the first bona fide sports organization
to have adopted guidelines regarding concussion."
Willer, who has been involved with hockey as a
player and coach for most of his life, says he agreed
to focus his efforts on hockey not only because he
loves the sport, but because he felt it would be an
effective conduit for introducing return-to-play
guidelines in other amateur sports, which in fact it

adopted them on an informal basis, with formal adoption
expected to take place sometime this year. When this happens,
the guidelines will apply to all international hockey events,
including Olympic hockey. Furthermore, if other, alternative
guidelines aren't adopted [by the Olympics], the return-to-play
guidelines of the International Ice Hockey Federation will
apply, by default, to all Olympic events."
Willer reiterates that the initial impetus for establishing return-to-play guidelines came from the AA but emphasizes that
these guidelines, while groundbreaking, do not translate well to
the realities of amateur athletics. " Prior to the AA announcing
their guidelines and publishing them in the journal ofNeurology,
there were no really authoritative guidelines anywhere. The
problem, however, was that the AAN guidelines were basically
written for professional sports or other environments where a
qualified trainer is on-site and the athletes' histories of concussion are available; in other words, they assume that there is
someone on the bench-either a physician or a professional
trainer-who can immediately appraise an athlete's condition
and determine if he or she can return to play at that time or not."

has been.
"Hockey was born and bred in Canada, so the
international sporting community still looks to
Canada and the CHA for leadership," he notes.
"Because the CHA adopted the guidelines, the
International Ice Hockey Federation also recently

S

11 111 111

e

r

2 0 0 0

Bu II a I o Physician

5

�when you 'sprain your
brain' it's a bigger deal
than spraining your knee
ing your knee or ankle. If you play on abum knee or live with abum knee, that's one
or ankle. If you play on a
bum knee or live with a
thing. But if you don't come back fully from abrain injury, it's different. You may be
bum knee, that's one
left with asignificant decline in mental functioning."
thing. But if you don't
come back fully from a
brain injury, it's different.
You may be left with a
When Lindros suggested to Willer that the UB professor apply
functioning."
significant
decline
in
mental
his expertise and influence toward helping establish guidelines of

tell the players. when you 'sprain your brain' it's abigger deal than sprain·

a similar nature in amateur sports, Willer and his collaborators
began by going to the CHA to meet with the individuals within
the association who develop educational programs for trainers.
"What ensued was a debate that centered on the questions,
'What can we realistically expect from the volunteer trainer/
coach on the sideline who is just somebody's mom or dad and
who has little or no medical background? What kinds of decisions
can we expect him or her to make about a player's condition?"'
explains Willer. Out of this discussion evolved the guidelines that
were adopted in 1998, which, according to Willer, have been
worded in such a way that they "not only make sense medically,
but are presented in a format that enables mom-the-team-trainer
to readily understand them-mom, that is, whose occupation
may be accounting, not medicine. " (See guidelines on page 7.)
Essentially, the guidelines adopted by the CHA
involve three basic modifications to the AAN guidelines. In addition to providing wording that better
helps inexperienced trainers identify a concussion
when it occurs, they recommend that all concussed
athletes be asked to see their physician before they
return to play. "Also, given the substantial increase in
risk for irreversible damage due to repeated concussions, if an athlete has three concussions in the same
year, it is recommended that he or she rest away from
the sport for the remainder of the playing season,"
explains Willer.
"These guidelines help make sure nobody goes
back to playing sports until they've fully recovered
from symptoms of a head injury," emphasizes Leddy,
who, as a team physician for intercollegiate athletics at
UB, knows firsthand about the dangers of concussive
injuries in amateur competition. "I tell the players,

6

8 u f fa I o Physician

S llllllll cr

2 000

Despite the apparent simplicity of the modifications made to
the AAN guidelines, they required a long series of discussions
with the CHA, with final wording changes taking place as late as
December of 1999. Lindros feels Willer's role was crucial to
making the project a success. "Due to his scientific expertise and
credibility, he [Willer] was able to facilitate the whole process
and gain the complete support of Canadian amateur hockey
through the CHA. He brought order and cohesion to the effort."

Physicians' Role aKey to Success
Because the guidelines recommend that players see their physician before returning to play, Willer and Leddy have also been
working to provide physicians with educational material about
concussion in an effort to help them better assess when it's

�safe to allow a child to return to playing sports. "Most family
doctors, internists and pediatricians probably don 't see enough
of these head injuries to really be very comfortable with treating
them, and it's not something they' re taught about in medical
school," notes Leddy. " 1 think most physicians need more
education about how to identify when a concussion has occurred,
as well as how to identify and treat symptoms of postconcussive syndrome."

F

urthermore, he cautions, "These injuries can be difficult to
diagnose, at best. There are a lot of symptoms that mimic
other things; also, athletes are prone to minimizing symptoms or downright denying them to the doctor. "
Toward the goal of educating physicians, Willer is developing an educational package that includes the return-to-play
guidelines, information on symptoms of concussion, and
assessment procedures for concussed athletes. Through his
affiliation with the OBIA, he is also working to organize a
medical advisory committee on concussions that, in addition

Management

e .o

eyes; or if eyes open, cannot

s

Guidelines Following Concussion

1. Remove from the contest.
2. Monitor symptoms (con-

Developed by the Ontario
Brain Injury Association and
approved by the Canadian
Hockey Association.

fusion, headache, etc.). If they
persist longer than 15 minutes from the time of injury,
the athlete should be referred
to a physician immediately.
The injury should then be
treated as a Second-Degree/
Complex Concussion.
3. Always check for a possible
neck injury.
4. Notify parent or guardian
and do not administer any
medication.
5. Cannot return to play
without approval of a physician and at least 24 hours of
symptom-free rest.

First-Degree/Simple
1. Confusion, also defined as
an altered state of consciousness, that lasts for less than 15
minutes (e.g., asks the same
question repeatedly, such as
"What happened?" or does
not know simple facts, like
who the opponent is or what
the score is).
2. No loss of consciousness.
3. Dizziness, headaches, nausea, lethargy; may have some
memory loss.

to establishing a consensus on post-concussive symptoms, will
sponsor educational conferences for health-care professionals.
" In the long run," he says, " the goal is to help physicians be a little
more astute at picking up symptoms and a little more aware of
the long-term consequences of concussions themselves."
Lindros commends this comprehensive approach to education because he fe els it can lead to protection for all children, not just those involved in sports. "These guidelines, and
the awareness they help create, apply to everyone, including
parents who see their child fall off the swing set and hit their
head. They aren ' t just for sports, but for life in general. What
they remind all of us is that the clock doesn't start ticking-a
child or an athlete doesn ' t go back to play-until he or she is
symptom-free at rest and with exertion for an appropriate
period of time.
" Essentially what we' re saying is, 'Let's have greater respect
for the body and things we do to the head. ' When the body isn ' t
treated with respect, a minor concussion can lead to significant,
long-lasting problems. "
CD

Second-Degree/Complex

seem to focus, does not answer to name, may be limp).
2. Loss of consciousness may
only last seconds but is still serious and must result in removal
of the player from the contest.

Management
ec m aos
1. Always check for injury to
the neck.
2. Remove from contest and
disallow return that day.
3. If unconscious, or condition
deteriorates, stabilize the head
and neck and activate the
Emergency Action Plan, including transfer by ambulance.
4.Cannot return to play without approval of a physician
and at least one week of symptom-free rest.

after any concussion requires
a physician 's approval. In order to make the most informed decision, the physician
must be made aware of the
history of concussions and
symptoms experienced by the
athlete. Another important
aspect of these guidelines is
that the only known cure for
concussion is rest. It takes
time for brain cells to recover.
When there is more than one
concussion in the same season, a physician may recommend a much longer period
of rest from sports. If an athlete has three concussions in
the same year, the physician
may recommend rest away
from the sport for the remainder of the playing season.
For more information, call

1. Confusion that lasts longer
than 15 minutes, or a loss of
consciousness (does not open

More than One Concussion
S·
S o
An essential aspect of these
guidelines is that return to play

S 11 mmer

the Ontario Brain Injury
Association pt 1-800-2635404, or visit their website at
www.obia.on.ca.

2000

B u II a I o P h y s i c i a n

7

�by S. I. Unger

Wake·

Difficult decisions for agifted young athlete
)

C)

was quite sure

hockey would be a big part of his life for as long as he
wanted it to be. Today, however, the 17-year-old from
Kenmore, New York, isn't quite so certain. That's because
Dan recently suffered two debilitating concussions that have left
him with a decidedly new appreciation for what it means to have
a healthy brain.
"Hockey has pretty much been my life. I started playing when
I was four, and since the seventh grade I've played on teams yearround," he explains.
And Dan hasn't been the only one enjoying the sport. "Hockey
is a bonding experience for our family," says his father, Tom. His
mother, Bonnie, says, "If you ever get to watch Dan play, the joy
is in seeing him skate; he's just such a beautiful skater."
john Mickler, Dan's coach at St. joseph's Collegiate Institute,
also gives Dan high marks for his prowess on the ice. "Dan has
been on the varsity since he was a sophomore. He's a very good
player. He's fast and aggressive and plays with great enthusiasm,
with a love of life."
Dan experienced his first concussion in September 1998, while
playing with an independent travel team, the Buffalo Saints, at a
tournament in Toronto, Ontario. "I was skating up the middle of
the ice and was hit behind with a cross-check," he recalls.
"He didn't know where he was. He was disoriented, his eyes
were dilated, and we knew he had to come off the ice," explains
Tom, who was in the stands when the injury occurred and felt
confused himself. "I know what needs to happen when a player
breaks his arm, but I didn't have any idea what to do when Dan
had his concussion," he says.
Despite his initial uncertainty, Tom had the paramedics at the
rink look at Dan. "They told us he had a head trauma, and that we
needed to watch him pretty carefully," he remembers.
The next day, the tournament was in full swing and Dan's team
was scheduled to play again. When Dan got up in the morning, his
father asked him how he felt, and he said he felt pretty good, that
he didn't have a headache and wasn't disoriented anymore.
''I'm not proud of this, but when he asked me if he could play
in the game that day, I said yes," explains Tom.
In looking back on that decision, Tom now knows how

8

Buffalo

Physician

S11mmer

2000

fortunate he and his family were that day. "It was a very rough
tournament. And while Dan didn't get hurt in the game, his
closest friend experienced a concussion in it."
The week following the tournament was the first week of
school for Dan. "I didn't know why I was there or what I was
supposed to be doing," he says. "I figure I'd had concussions
before-maybe from playing football in the neighborhoodbut nothing ever stopped me before like this. I was startled."
Over the following weeks, Dan's symptoms cleared up and he
was again able to immerse himself in the sport he loved.
A year went by, and Dan's concussion seemed a thing of the
past. Then, on October 24, 1999, at the close of his season with
the Buffalo Saints, he suffered a second, even more serious,
concussion. The incident occurred at a tournament in Cleveland,
Ohio, where Dan had traveled with the parents of a friend on the
team. Despite the severity of his injury, no one seems certain
about what actually happened.
"It was the third game of the tournament, and I remember
playing really hard and scoring a goal. After the game, we had free
time on the ice, but I remember going over to the bench and just
sitting down," says Dan. "I thought maybe I was super tired."
Later, in the locker room, Dan's coach came in to talk to the
team, but Dan couldn't understand him."[ didn't know what he
was saying. I was lightheaded and dizzy, and I began to wonder
what I was doing there and where my parents were. I almost got
kind of panicky. I didn't even know what day it was."
Although scared, Dan didn't tell his coach what he was feeling.
''I'm not a big guy," he explains. 'Tm only about 5' 8", and I
didn't want to complain, but I was so tired I couldn't stand up."
When his teammates dressed and left the locker room, Dan
stayed behind. "The parents of Dan's friend waited in the lobby
and became alarmed when he didn't come out," recalls Tom.
"When the father finally went to look for him, he found Dan in
the locker room alone, sitting on the bench. He didn't know what
was going on or what had happened."
All Dan remembers about the remainder of that road trip is
that he slept in the car during the entire drive back to Buffalo.
Bonnie Sanderson called Dan's pediatrician, who told her
Dan had to stay off the ice for two weeks. Tryouts for the school

�because l wasn't in shape, that maybe I had heat exhaustion," he says.
Dan didn't try to skate again until the week ofThanksgiving, at
which time he traveled with the team to Detroit and played in a
game, the first since his concussion. Again, he felt as though he
were suffering from heat exhaustion. "After that, I knew l needed
to go to the doctor again; I just wasn't getting better," he says.
The following Monday, Bonnie called a friend of theirs who
is a neurologist, and he told her to bring her son in immediately.
"He gave Dan an MRI and a complete examination and told us he
couldn't be on the ice for another two or three weeks, or until his
symptoms went away," says Bonnie.
On December 15, 1999, Dan returned to play and has not
reinjured himself since.
"This last concussion was our wake-up call," says Tom, who
accepts that Dan's playing days may be numbered.
Dan, too, knows there may be difficult decisions to make in
the future, but says he no longer looks at hockey in the same way.
"Alii have to do is remember those couple of
months when I couldn't think in math class
and had to ask everyone to repeat things they
Normally,l'm agood student, but I couldn't sit still in class for five minutes. I wanted to
said to me four times. What's happened to me
has brought me down to thinking about what
get up and walk out. I just had no ambition to be there," says Dan. "I slept a lot, had a
I really want to do. I'm starting to think about
headache all the time, was dizzy, and my head felt foggy.l didn't want to do anything."
the pros and cons of continuing to play."
As he helps his son grapple with the
potential long-term implications of his
injuries, Tom also ponders whether better
Bonnie Sanderson also
decisions about Dan's health could have
noticed big changes in her
been made from the outset. "As parents, I
son. "Dan is usually on top
think we needed a little more training and
of things, both at school
guidance.
We need more information so we
and at home. But many
can
all
be
on the same page when a player
times when I would talk to
gets
a
concussion.
It would have been helpful
him, I'd literally have to
if
we
had
had
more
explicit instructions
say, 'Dan, are you with me?'
about
what
to
look
for,
what to do."
He wasn't himself. He was
Bonnie
sees
the
problem
in an even larger
acting very goofy; that's the
"I
feel
it's
really
a
disservice
when you
context.
best way I can describe it."
read in the paper that a pro player has had a
While Dan didn' t play
concussion
on Sunday and then is back at prachockey, he did go to his
tice
on
Thursday
and back playing in a game
team's practice sessions,
that
next
week.
The
media treats concussions
where he'd watch from the
like
a
broken
leg.
They
make it out to be nobench. "I wanted to stand
thing,
so
it's
been
hard
to
know what to think."
on the bench to watch, but
Like
Tom,
Bonnie
feels different decimy balance wasn't good
sions
would
have
been
made
had she known
enough to do that, so I rein September 1998 what she knows today. "I
member I had to stand on
would
never have a child of mine go back out
the floor instead."
on
the
ice if I knew it would endanger his
On November 17, Dan
health,"
she says. "Yes, hockey is important to
played in a scrimmage, but
us
as
a
family,
but, as I tell Dan, 'I like you
didn't feel well afterwards,
just
the
way
you
are."'
4D
he says. "I thought it was

team were coming up, but since Dan had made the team the year
before, Coach Mickler suggested he take some extra
time off in addition to the two weeks.
Unlike what happened after his first concussion, however,
Dan's symptoms didn't go away, so Bonnie took him to see their
pediatrician, who told her Dan couldn't return to play until his
headaches subsided.
"Normally, I'm a good student, but I couldn't sit still in class for
five minutes.! wanted to get up and walkout. I just had no ambition
to be there," says Dan. "I slept a lot, had a headache all the time, was
dizzy, and my head felt foggy. I didn't want to do anything.
"I really began to wonder what was wrong with me, what was
happening to me," he adds. "It would have been easier if there
had been a clear-cut blow to my head that caused my concussion,
but we watched film from the game later, and even though I
could see I was hit in the head a few times, nothing stood out as
the hit that caused my concussion."

5 "

111 111

er

200 0

Buffalo Physician

9

�I
I
by S . A. Unger
ne of the reasons why many experts feel concussion is such
an overlooked problem-even a "hidden epidemic"-is
because the affected organ is itself hidden from view.
"Yet, when a brain is concussed, if you look at it on a
microscopic or cellular level, there's a whole cascade of
events taking place, including changes in blood flow and
glucose and electrolyte metabolism," explains John Leddy, MD,
UB associate professor of clinical orthopaedics and associate
director of the university's Sports Medicine Institute.
While physicians still don't understand all the physiological
changes a brain undergoes when con cussed, what they do know
is that concussions cause deficits in neurocognitive abilities,
especially when more than one concussion is suffered within
a short period of time.
Due to recent advances in neuropsychology, neurocognitive tests are now available that measure these deficits
more precisely than ever before. When used in conjunction with
a standard neurological examination, they become powerful
tools for assessing whether an individual has recovered from a concussion.

Neurocognitive tests and the data they provide are of particular
interest to professional sports organizations, which today are
experiencing increased pressure from players' unions and
insurance companies to adopt return-to-play guidelines that
better protect athletes from preventable, career-ending head
injuries. (See article on return-to-play guidelines established
in 1997 by the American Academy of Neurology, page 2.)
Several years ago, in response to these pressures, both the National Hockey League (NHL) and the National Football League
( FL) began participating in the HL!NFL Players' Association
Concussion Testing Project, developed by Mark Lovell, PhD, a
neuropsychologist at Henry Ford Hospital, in Detroit, Michigan.
(Participation in the project is mandatory for NHL teams and
voluntary for NFL teams. Currently, about 85 percent of the FL
teams participate, not including the Buffalo Bills.)
As part of the project, no athlete can practice or play with a team
until he undergoes a baseline neuropsychological examination. In
the event of a head injury, he is reexamined and the data are then
compared to the "healthy" baseline as a means to measure the
severity of his injury and his progress toward recovery.
In 1997, Lovell contacted Ralph Benedict, PhD, a neu ropsychologist at the University at Buffalo School of Medicine and
Biomedical Sciences, and asked if he could incorporate in the
Concussion Testing Project a neurocognitive test Benedict had
developed called the BriefVisuospatial Memory Test.
As a result, Benedict's test is now a key component in the
professional sporting world's attempt to keep players from
returning to play too soon following a concussion.
Also used in the project is a test called the Hopkins Verbal
Learning Test. While completing his postdoctoral training and
residency at the Johns Hopkins University, Benedict took a lead
role in revising this test, which was originally developed by
Dr. Jason Brandt.
In addition to providing the Concussion Testing Project with
the tools it needs to test the players, Benedict is also serving as a
consultant with the project. In this capacity, he is available on an
on-call basis should an NHL or NFL player be concussed while
playing in Buffalo and require neurocognitive evaluation.
Benedict's Brief Visuospatial Memory Test is also widely
used outside of professional sports to evaluate cognitive
function in individuals affected by brain injuries or disease. 4D

�------------------------------------------------------------

-------

UB Selected as Site for High School Pilot Program
n a related development, the University at Buffalo was
informed in May 2000 that it has been selected as one
of three national test sites for a new computer-based
neurocognitive assessment program for high school
athletes. (The other two sites are the Mayo Clinic and
Henry Ford Hospital.) Developed by the same researchers
at Henry Ford Hospital who developed the NHL/NFL
Players' Association Concussion Testing Project, the new
program involves giving high school students an
abbreviated version of the professional-level test that can
be administered by computer in 15 to 20 minutes.
The UB effort--led by Barry Willer, PhD, UB professor of
psychology, in collaboration with the Ontario Brain Injury
Association and Brock University-will involve high school
students in Buffalo, New York, and Niagara, Ontario.

Significance of Cong·term
ncuss·suotie)effects:

"At minimum, parttopating schools are expected to
assess every student involved in sports. What would be ideal,
however, would be for all students to be assessed, since
organized sports-while they do constitute high-risk
activities-account for only about 15 percent of all concussions in this population," explains Willer.
"Participation in this project to assess the feasibility and
validity of the brief assessment procedure could be a major
factor in the prevention of cognitive disabilities in young
people," he adds.
For more information on the HLINFL Players' Association Concussion Testing Project, e-mail Dr. Benedict at
benedict@acsu.buffalo.edu. For more information on the
new high school testing project, e-mail Dr. Willer at
bswiller@ acsu.buffalo.edu.

The Impact of
Concussions on Youth
•:• One-third of youth experience a concussion before the
end of high school.
•:• One-half of all concussions are accompanied by
loss of consciousness.
•:• Average age of concussion
is age 10.
•:• For children who experience more than one concussion, there is an increased
likelihood that the problems
described above will remain
long term.
•:• Children with protracted
problems stemming from
concussion are less likely to
attend college.
•:• Children who return to play
too soon after concussion may
experience very serious consequences, including secondimpact syndrome, which can
result in death.
CD

•:• Ringing in the ears
•:• Change in appetite
•:• Loss of taste/smell

Behavioral
•:• Irritable/ Agitated
•:• Quick temper
•:• Can ' t sit still/ ervous
•:• Moody/ Depressed/
Tearful
•:• Sleep problems
Cognitive
•:• Mentally "foggy"
•:• Memory difficulties
•:• Poor concentration/
attention
•:• Poor judgment
•:• Fatigue
•:• Difficulty finding words
Physical
•:• Headache
•:• Dizziness
•:• Fatigue/ Drowsiness
•:• Blurry/ Double vision
•:• Light/Noise sensitivity

S

11

m

111

e r

2 0 0 0

Buff a I o Physician

.

.
~

..

11

�M

B
M

E

D

C

A

L

ScHOOL

N

E

w

s

y

Second·look Day

D

KINNAMON

ln · depth preview for prospective students

\ 40 ~

D the first

spective students could talk to first-year students. One

University at Buffalo School of Medicine and

popular session was the student question-and-answer

l

Biomedical Sciences "Second-Look Day" on

panel, which included six students in different phases of

April 29, 2000. The event was planned to give

their medical education at UB. Topics ranged from the

accepted students more interaction with cur-

MD/MBA dual-degree program to long-distance rela-

rent medical students and another chance to

tionships, what day-to-day life is like, and opportunities

see where they might be spending the next

available during the clinical years. For julie Baker, a UB

four years.

undergraduate, the day was invaluable. "It helped me feel

The idea came to first-year students
Laura Cinski, )ill Albrecht and Steve

more comfortable about my decision to continue at UB."

Turkovich as they discussed their Inter-

First·year student Lisa Reaves
talking with Jim Krygowski, a
biology major from Grove City
College in Pennsylvannia.

view Day experiences. The students felt

continued to get acquainted at dinner

so focused on interviewing that they

and then enjoyed a night on the town

weren ' t able to properly evaluate what

with their new friends. "I was a bit

UB had to offer them. They also thought

nervous to meet my future class-

Interview Day didn't offer enough

mates," says Joe Kita, a St.

student contact.

Bonaventure student, "but I found

Albrecht had attended a similar type

that we have the same career goals

of event at another school last spring

and dreams. l felt like I could connect

and felt it would be an ideal model for UB. "Second-

to so many people and became excited

Look Day lets the school sell itself," she says. "We want

about the next four years."

people to make an informed
decision and to be happy here.
The best way to ensure this is
to give them lots of information about what UB's medical
school is like from a student's
perspective."
The inaugural SecondLook Day at UB included
mini-lectures in anatomy and

L

physiology presented by

.

Charles Severin, MD, PhD,

z

and Perry Hogan, PhD; smallgroup problem-based learning
sessions with Murray Ettinger,
PhD; student-led tours of
facilities; and breakfast and
lunch meetings where pro-

12

I u f fa I o Physician

Afterwards, a group of the prospective students who
had been corresponding by e-mail

S 11mm e r

2 000

CD

First·year student Joanna
Shaw, below left, talks
with prospective
students. left to right.
Joyce Yan Li of Yale
University, Julie Baker of
the University at Buffalo,
and Penny Lawson of the
University of Rochester.

�The An of

New tutor i al group helps first·year students

lutorin Science
Hi·

"l;J

,

&gt;O

" experience gained by

some second-year students in the University at Buffalo

refer them to a better information source," says Mato.

School of Medicine and Biomedical Sciences is now

In addition to giving tutors the

helping first-year students master their medical school

opportunity to serve the school,

coursework. The Buffalo Medical Tutorial Group,

the tutorial program gives them

launched in january 2000, consists of second-year

the chance to review for board ex-

students who volunteer to share not only their prior

ams and to learn how to effectively

knowledge of physiology, anatomy, biochemistry and

communicate scientific ideas. It's

the other first-year subjects, but also their insights on
how best to learn them and have a successful first year.

and foster camaraderie among

The tutorial group is the brainchild of second-year
student Anthony Mato, who, while an undergraduate at
Cornell University, tutored biochemistry and organic
and general chemistry in its Learning Skills Center. Inspired by that program, Mato approached former UB
assistant dean Thomas D. Flanagan in October 1999 with
the idea of starting a tutorial program at UB.
"Our goal is to offer students help during evening
hours when professors aren't around," says
Mato. "We wanted to create a resource for
students studying at night who otherwise
couldn't get questions answered until their
professor is available." While the group en-

~I

K

I

courages students to consult their professors
first, sometimes students are more comfortable talking to
their peers, Mato says. "Some first-year students are intimidated by the faculty, and the idea ofcallinga professor
at home is a big deal to them. That's why we're here."
Four nights a week students can go to Sherman Hall

also an excellent way to introduce
first- and second-year students.
The group, which attracted 22
student volunteers its first year,

First·year student Lily Belli, /efr. being tutored by Anthony Mato.

enjoys strong faculty support.
Mato met with each of the first -yea r professors individually to discuss how the program would work with their
courses, and the group communicates regularly with
professors about any changes in course material. Each
department provided a complete set of
their courses' required textbooks, and
B y
faculty members donated meeting space, a
D
computer and a teaching microscope.
A \I 0 'I
Physiology professor james T. Goldinger,
PhD, is their faculty advisor.
"This [first] year's class is quite successful," says Perry
Hogan, PhD, professor of physiology. "They're calmer
about their involvement and their progress. The tutorial
group could reasonably take credit for their students'

imln•eltaH
tlllir pncress. De
tltlriallfll.
CIIN I'IISIII~Iy

talll cre~it fer tlllir

strints's...tller

smoother progress through the medical curriculum."

and drop in on a number of sessions that take place in the

But the tutorial group's biggest fans are students. "I

physiology department conference rooms. These infor-

perform better on exams," says Amy Puzio. "Rather than

mal get-togethers can take the form of one-on-one meetings, Q -and-A sessions, roundtable discussions or test

staring at a textbook, talking about the material solidifies
the information for me." Mato's efforts were recently

reviews. "Our time is owned by whoever walks in the

honored with the school's student-nominated Louis A.

room. We' re there to discuss whatever the students want,"

and Ruth Siegel Award. He is the first student to receive

says Mato. Each tutor commits to a minimum of two

this award, which is traditionally presented to faculty.

hours a week and teaches a subject they did well in and are

"A lot of people say they go to medical school because

excited about. "We might not know the answer to every

they want to help people," says Mato. "This program is a

question, but we answer to the best of our knowledge or

true test of that."

4D

Summer

2000

I u ff a I o Pb y sic ian

13

�MEDICAL

ScHOOL

N

E

w

s

Dorothy Adler
Thomas Jefferson University

Paul Bogner
Pathology, University of
Michigan Hospitals

PHILADELPHIA, PA

ANN ARBOR, Ml

Tamara Alberti

Anthony Bottiggi

Pediatrics,
Medical College of Virginia

General SLirgery, University
of Kentucky Medical Center

RICHMOND. VA

LEXINGTON, KY

Benjamin Alderfer
Psychiatry, University of
Colorado School of Medicine

George Boucher

DENVER, CO

Graduate Medical-Dental
Education Consortium

Family Practice,

his year's National Residency Matching Program (NRMP) results
were announced on March 16 by Dennis Nadler, MD, associate
dean in University at Buffalo's School of Medicine and Biomedical
Sciences. Of UB's graduating medical students, 58 percent were
placed in primary care residencies. Eighty·one percent of the
students received their first, second or

BUFFALO,

Y

BUFFALO,

Y

Mathijs Brentjens

Internal Medicine, Emory
University School of Medicine
ATLANTA, CA

third choice of placements. Twenty· nine

AkkiiAii

Internal Medici11e,

Suzanne Burke

percent will stay in Buffalo to train in

University of Florida
Health Science Center

Emergency Medicine, SUNY/

the Graduate Medical Dental Education

jACKSONVILLE, FL

Consortium, while 52 percent will go

Steven Ambrusko
Pediatrics, SUNY/Buffalo
Graduate Medical-Dental
Education Consortium

out of state.
In the primary care specialties, 34

BUFFALO, NY

students were placed in internal
medicine, 15 in pediatrics, 12 in family medicine, 9in medicine/
pediatrics and 5in obstetrics/gynecology.
"Our students do consistently well in the NRMP with placements
in some of the top programs in the country," says Nadler. "Our
record in 'early' subspecialty match is equally impressive. We are
extraordinarily proud of our students' achievements."
Nationwide, 51 percent-or 6,931 graduating U.S. medical

Jeffrey Amodeo
General SLirgery, SUNY/
Buffalo Graduate Medical-Dental
Education Consortium

Buffalo Graduate MedicalDental Education Consortium
BUFFALO, NY

Anthony Caprio

Internal Medicine, University of
Rochester/Strong Memorial Hospital
ROCHESTER, NY

Thomas Caprio

Internal Medicine, University of
Rochester/Strong Memorial Hospital
ROCHESTER, NY

BUFFALO, NY

Daniel Carl
Lisa Apfel

Intemal Medicine,

General SLirgery, SUNY/Buffalo

Medical College of Virginia

Graduate Medical-Dental
Education Consortium

RICHMOND, VA

BUFFALO. NY

Hope Cawdery

Internal Medicine, Duke University
Michael Banas

Medical Center

school seniors-matched to afirst·year residency position in

Internal Medicine, SUNY/Buffalo

DURHAM, NC

one of the generalist disciplines. This is the lowest generalist

Graduate Medical-Dental
Education Consortium

Leslie Chamberlain

specialty match rate since 1995, when seniors also matched at

BUFFALO,

Y

AmyBeuler

51 percent.
According to the NRMP, 25,056 individuals participated in

Family Practice, SUNY/Buffalo
Graduate Medical-Dental
Education Consortium

Medicine/Pediatrics,
Ohio State University
Medical Center
COLUMBUS, OH

Julie Cheng

Pediatrics,

the match this year, aslight decrease from the 26,462 who

BUFFALO, NY

participated in 1999. Of the total active applicants, 73.4 percent

Howard Blumstein

Loma Linda
University

were matched, a4percent increase over last year.

Internal Medicine, UMDNJNew Jersey Medical School

CA

-S.A . UNGER

14

Ramune Alexander
Family Practice, SU Y/Buffalo
Graduate Medical-Dental
Education Consortium

Medicine/Physical Medicine and
Rehabilitation, SU Y/B uffalo

Buffal o Ph ysici an

Summer

2000

PISCATAWAY, Nj

�James Chevalier
Internal Medicine, ew York
Presbyterian Hospital-Cornell

Christopher Di Maio
Internal Medici11e,
Thomas jefferson University

Michelle Ehrlich
Dermatology,
Cleveland Clinic Foundation

NEw YORK, NY

PHILADELPHIA, PA

CLEVELAND, OH

Frederic Chi
Orthopedic Surgery,
University of Rochester/
Strong Memorial Hospital

Louis Domenico
Medicine (Prelim), SUNY/Buffalo
Graduate Medical-Dental
Education Consortium

Catherine Falkner
Obstetrics/Gynecology, SU Y
Upstate Medical Center

ROCHESTER.

Y

Michael D'Angelo
Internal Medicine, SUNY/Buffalo
Graduate Medical-Dental
Education Consortium

BUFFALO,

Y:

Diagnostic nadiology,
Penn State Geisinger
HERSHEY, PA

James Doran
Undecided

Jaimie De Rosa
Surgery (Prelim),
Boston Medical Center

Holly Drexler
Family Practice,
Williamsport Hospital

BOSTON, MA;

WILLIAMSPORT, PA

BOSTON, MA

Todd Duggan
Internal Medicine,
Medical College of Virginia

James De Santis
Surgery (Prelim), SUNY/Buffalo
Graduate Medical-Dental
Education Consortium

Kimberly Dumoff
Pathology, University of Pennsylvania

BUFFALO, NY

PHILADELPHIA, PA

Sorabh Dhar
Medicine/Pediatrics, SU Y/
Buffalo Graduate MedicalDental Education Consortium

Zeynep Ebcioglu
lntemal Medicine,
Thomas Jefferson University

BUFFALO,

Margaret Eberl
Family Practice, SUNY/Buffalo
Graduate Medical-Dental
Education Consortium

Y

Kenneth Harris
Pathology, Massachusetts
General Hospital

SYRACUSE, NY

Ani Fleisig
Gweral Surgery, Georgetown
University Hospital

BOSTON, MA

Nishi Harvey
Medicine (Prelim),
St. joseph's Hospital

WASHINGTON, DC

BUFFALO, NY

Otolaryngology,
Boston Medical Center

Steven Lo. 26. and his fiancee and classmate
Reshma Katira, 25. were pleased-and relieved
-to discover they will both be going to Chicago.

RICHMOND, VA

PHILADELPHIA, PA

BUFFALO. NY

Scott Frank
Surgery (Prelim),
Mercy Hospital of Pittsburgh

ANN ARBOR, Ml

PITTSBURGH, PA

Bret Gelder
Surgery (Prelim), SU Y/Buffalo
Graduate Medical-Dental
Education Consortium
BUFFALO, NY

SumanGona
Transitional, St Vincent's Hospital
NEW YORK,

Y:

Ophthalmology,
Mt . Sinai School of Medicine

Aram Hezel
Intemal Medicine, Beth Israel
Deaconess Medical Center
BOSTON, MA

Michael Hochberg
Surgery (Prelim),
Mt. Sinai School of Medicine
NEW YORK,

Charles Howarth
Medici11e, Columbia Bassett
COOPERSTOWN,

Y

AllysonHowe
Family Practice,
Travis Air Force Base
Fairfield, CA

NEW YORK. NY

Niels G•thgen
General Surgery, Hospital of
St. Raphael
EW HAVEN, CT

Shirley Huang
Pediatrics, University of
orth Caro lina Hospital

Rose Graham
Pediatrics, Children's
Hospital of Philadelphia

c

CHAPEL HILL,

PHILADELPHIA, PA

Madhuri Guntupalli
Surgery (Prelim), RushPresbyterian-St. Luke's Hospita l
CHICAGO. IL;
Ophthalmology, RushPresbyterian-51 Luke's Hospital
CHICAGO, IL

Alissa Huston
lntemal Medicine, University
of Rochester/Strong
Memo rial Hospital
ROCHESTER, NY

Adriana Kaczaraj
Internal Medicine,
Mt. Sinai Hospital
NEW YORK,

John Hannibal
Law School

Y

Y

Kevin Stanley, 25. of
Oswego. NY,
vociferously shares
his results. On his
right is Madhuri
Guntupalli and to his
left. Andrew Stone.

.
.•

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Second·year student Sandy
Singh and his sister. Abhilasha
(Abby) Singh, 25. below. await
news about her match results.

w

Jennifer Kam

Brian Klagges

William Lighthart

Medicine (Prelim), SUNY/Buffalo

General Surgery,

Surgery (Prelim),

Graduate Medical-Dental
Education Consortium
BUFFALO, NY:

Diagnostic Radiology,
Rochester General Hospital
ROCHESTER, NY

HeyJooKang

Obstetrics/Gynecology, New York
Presbyterian Hospital-Cornell
NEW YORK,

Y

Reshma Katira

Surgery (Prelim), RushPresbyterian-St. Luke's Hospital
CHICAGO,

IL:

Ophthalmology, RushPresbyterian-St. Luke's Hospital
CHICAGO,

IL

Mark Kenyon

Pediatrics,
Children's Memorial Hospital
CHICAGO,

IL

ew England Medical Center

BALTIMORE, MD

Marta Kolthoff

Jennifer Lin

Obstetrics/Gynecology,
University Health Center

General Surgery, University
of North Carolina Hospital

PITTSBURGH, PA

CHAPEL HILL,

Matthew Krauza

Steven Lo

Internal Medicine, SU Y/Buffalo

Medicine (Prelim), University

Graduate Medical-Dental
Education Consortium

of Illinois College of Medicine

BUFFALO,

Neurology, University of Chicago

CHICAGO,

Y

CHICAGO,

Sharmeela Kuperan

Medicine (Prelim), SUNY/Buffalo
Graduate Medical-Dental
Education Consortium
BUFFALO, NY

HasitMehta

Diagnostic Radiology,
University of Texas
Southwestern Medical School
DALLAS, TX

IL;
IL

Melinda Mesmer
Medicine, Yale-New Haven Hospital
NEW HAVEN, CT

Alka Patel

Todd Loftus
Psychiatry, New York
Presbyterian Hospital-Cornell

Medicine/Pediatrics, University
Hospital of Cincinnati
CINCINNATI, OH

Darshan Patel

Justin Kwan

Michael Logue

Family Practice, Pinnacle Health-

Medicine (Prelim),

Intemal Medicine, New York

Harrisburg Hospital

Long Island jewish Hospital

Presbyterian Hospital-Cornell

HARRISBURG, PA

NEW HYDE PARK, NY;

NEW YORK,

Neurology,
Baylor College of Medicine

General Surgery, SU Y/Buffalo
Graduate Medical-Dental
Education Consortium

HOUSTON, TX

Y

c

EW YORK, NY

Eric Kirker

BUFFALO,

Union Memorial Hospital

BOSTON, MA

Y

Penn State Geisinger
DANVILLE, PA

BUFFALO, NY

Dionysia Mamais

Jesenia Peiia

Medicine/Pediatrics,

Family Practice, SU Y/Buffalo
Graduate Medical-Dental
Education Consortium

Emergency Medicine,

Jason Lake

Internal Medicine, Walter Reed
Army Medical Center
WASHINGTON, DC

St. Vincent's Hospital

Charles Lau

NEW YORK,

Medicine (Prelim), Brigham &amp;
Women's Hospital
BOSTON, MA;

Diagnostic Radiology, Hospital

Y

Rosemarie Mannino

Everett Porter

Medical College of Virginia

Internal Medicine, University
of Rochester/Strong
Memorial Hospital

of the University
of Pennsylvania

Andrew Mayer

PHILADELPHIA, PA

Internal Medicine,

BUFFALO,

Y

Medicine/ Pedia tries,
Mt Sinai Hospital
EW YORK,

Cedars-Sinai Medical Center
Los ANGELES, CA
Donald McDonald

Y

Graduate Medical-Dental
Education Consortium
y

Daniel McKenna
Pediatrics, SU Y/Buffalo
Graduate Medical-Dental
Education Consortium

Robert Lewis

BUFFALO,

Internal Medicine,

Talia McNamara
Psychiatry, University of
California at Los AngelesSan Fernando Valley

Lenox Hill Hospital
NEw YORK, NY

ROCHESTER,

Y

Erin Reardon

Emergency Medicine,
Morristown Memorial Hospital
MORRISTOWN, NJ

Internal Medicine, SUNY/Buffalo

BUFFALO,

Jennifer Lee

BUFFALO, NY

Intemal Medicine,
RICHMOND, VA

Lynn Lawrence
Pediatrics, SUNY/
Buffalo Graduate
Medical-Dental
Education
Consortium

Donna Peace

Family Practice, SU Y/Buffalo
Graduate Medical-Dental
Education Consortium

Jason Lorenc

Y

SEPULVEDA, CA

Tara Reimer
Pediatrics, SUNY/Buffalo
Graduate Medical-Dental
Education Consortium
BUFFALO, NY

Gretchen
Schueckler. 32,
from Buffalo. NY.
on the phone to
spread the news
while receiving
ahug from
Catherine (Kate)
Falkner, 25.

�--------------

-

- - - - - - - - - - - - - - - - - - --

--

----------

-----

NehaSheth

Richard Telesco

Pediatrics,

Pediatrics,

Priya Wagner
Pediatrics, University of Connecticut
FARMINGTON, CT

University Hospitals of Cleveland

Medical College of Virginia

CLEVELAND, OH

RICHMOND. VA

Phaelon Silva

Felicia Tenedios

Melissa Reyes

Obstetrics/Gy!Iecology,

lntemal Medicine, New York

Hospitals of C leveland

Family Leave

Madigan Army Medical Center

Presbyterian Hospital-Cornell

CLEVELAND, OH

TACOMA, WA

NEW YORK, NY

Abhilasha Singh

Michael Tinnesz

Emergency Medicine, McGaw Medical Center-Northwestern University

Emergency Medicine, SUNY/Buffalo
Graduate Medical-Dental
Education Consortium

David Rice

lntemal Medicine, Wright
Patterson Air Force Base
DAYTON. OH

CHICAGO, IL

Walter Walek

Surgery (Prelim), University

BUFFALO, NY

CamiRiley

Intemal Medicine, SU Y/Buffalo
Graduate Medical-Dental
Education Consortium

Graduate Medical-Dental
Education Consortium

Medicine (Prelim), SUNY/Buffalo
Graduate Medical-Dental
Education Consortium

Medical Center Hospital

St. joseph's Hospital

Medicine/Pediatrics, Albany

ALBANY, NY

CHICAGO, IL

Y, NY

Lirim Tonuzi

Graduate Medical-Dental
Educatio n Consortium

Medicine (Prelim), SU Y/Buffalo

BUFFALO,

Y

Matthew Smith

iiiternal Medici11e, SUNY/Buffa lo
Graduate Medical-Dental
Education Consortium

Graduate Medical-Dental
Education Consortium
BUFFALO, NY;

Neurology, SU Y/Buffalo
Graduate Medical-Dental
Education Consortium
BUFFALO,

BUFFALO, NY

Graduate Medical-Dental
Education Consortium
BUFFALO. NY

MEMPHIS, T

Christopher Santangelo

Andrew Stone

Psychiatry,

Internal Medicine,
ew England Medical Center

WASHINGTON. DC

BOSTON, MA

Gretchen Schueckler
Internal Medicine, Brown University

Jason Stopyra
Emergency Medicine, Wake Forest
University Baptist Medical Center

Michelle Watson

Surgery (Prelim), SU Y/Buffalo

Psychiatry, SU Y/Buffalo

Kevin Stanley
Orthopedic Surgery, Un iversity of
Tennessee College of Medicine

Georgetown University Hospital

Medical Center Hospital
ALBA

BUFFALO, NY;

Diagnostic Radiology, SUNY/Buffalo

Robert Wang

Rommel Tolentino

BUFFALO, NY

Samuel S'doia

ANN ARBOR, Ml

Transitional, Catholic Health-

Beth Smith

Family Practice, SUNY/Buffalo

Stephen Wampler
Family Practice, University
of Michigan Hospitals

Medici11e/Pediatrics, Albany

Igor Sirotkin

BUFFALO, NY

Lynne Ross

y

Graduate Medical-Dental
Education Consortium
BUFFALO, NY

Theresa Wendel

General Surgery, RushPresbyterian-St. Luke's Hospital
CHICAGO, IL

Michael White

Judith Toski

Emerge11cy Medicine, Eastern
Virginia Medical School

Emergency Medicine, SU Y/Buffalo
Graduate Medical-Dental
Education Consortium

Melissa Wolf

BUFFALO, NY

Family Practice, University

ORFOLK, VA

Hospitals of Cleve land

Amy Van de Water

Medicine/Pediatrics, University of

CLEVELAND, OH

Minnesota Medical School

Emily Wong

MINNEAPOLIS, M

lntemal Medici11e, University
of Michigan Hospitals

Rosalia Viterbo

General Surgery, SUNY/Buffalo

ANN ARBOR, Ml

WINSTON-SALEM, NC

Graduate Medical-Dental
Education Consortium

Nora Yip

Transitional, Mercy Hospital

Marisa Stumpf

BUFFALO. NY

Un iversity of Connecticut

PITTSBURGH, PA

Obstetrics/Gy!Iecology,

PROVIDENCE. Rl

Bryan Scott

ew England Medical Center
Tracey Shanahan
Pediatrics, Ohio State
University/Chi ldren 's Hospital
COLUMBUS, OH

Kathryn Shanks

Emergency Medicine, SU Y/Buffalo
Graduate Medical-Dental
Education Consortium
BUFFALO,

y

--

BOSTON, MA

Britta Svoren
Pediatrics, Boston Combined
Pediatric Residency
BOSTON. MA

FARMINGTON, CT

Roy Vongtama

Medici11e (Prelim),

Vladimir Zelenko

Graduate Hospital

Rabbinic Educatio11

PHILADELPHIA, PA;

Radiation Oncology, University of
California at Los Angeles

JamaiZohur

LOS ANGELES, CA

Buffalo Graduate MedicalDental Education Co nsortium

Cheryl Taurassi

Eric Waffner

Pediatrics,

l11temal Medicine, SUNY/Buffa lo

Long Island jewish Hospital

Graduate Medical-Dental
Education Consortium

EW HYDE PARK, NY

Ge11eral Surgery,

BUFFALO,

Medicine/Pediatrics, SU Y/

BUFFALO,

Y

Y

S11mmer 2000

luflalo Physician

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Songs Give S1 Million to School
p
and his wife, Janet H. Sung, MD,
\1
founder and president of four radiological practices in Western New York, including
Windsong Radiology, P.C., are giving a $1 million cash scholarship gift to the University
at Buffalo's School of Medicine and Biomedical Sciences.
"What better way to show our gratitude and appreciad
tion," says John Sung, "than to provide scholarships for UB

CFO ) \\

Children's
Health for Kids

medical school students who have good grades, need the
money and demonstrate soundness of character, including a genuine, caring attitude, generosity of spirit and leadership potential?"
Janet Sung concurs that the gift to the university "has made us very
happy because my husband is finally realizing a dream that began
when he was a college student in Korea, working his way through

"What better way to
show our gratitude
and appreciation."
-John Sung

school and depending also on scholarships."
The Sungs' story began in Korea, where both were born and attended college.
They moved to the United States as a newly married couple in 1972, arriving in New
Jersey with only $200. While Janet Sung completed her residency, John Sung earned
his MBA from Seton Hall University and completed his CPA training.

In 1977, they moved to Buffalo, where janet Sung held positions in radiology with area
hospitals. John Sung worked first for the accounting firm Peat Marwick Mitchell, then taught at
Daemen College before working full time with his wife.
In 1987, the Sungs opened Harlem Radiology, P.C., in a converted Pizza Hut. Today they
operate Windsong Radiology, which employs over 120 people and is the only free-standing clinic
in Western New York with full diagnostic accreditation from the American College ofRadiology.
-SUZANNE CHAMBERLAIN

Frawley Establishes Fellowship Award
, .\ LJ

1

made the first presentation of the

"Frawley Fellowship Award" to V. Uma Valeti, MD, who is currently completing his
residency training in internal medicine at the University at Buffalo School of Medicine
and Biomedical Sciences. Frawley established the fund this year to support "worthy
medical/surgical residents for whom medical research represents a primary personal
interest and passion." Valeti, whose goal is to pursue an academic career in cardiology,
has completed cardiovascular research in the laboratory of Dr. John Canty. Receipt of the
Frawley Fellowship will make it possible for him to continue his research on ischemic cardiomyopathy and hibernating myocardium.
Frawley began his own research career with the study of adrenal
physiology at UB and then at Harvard University. He continued research on the adrenal cortex and also in carbohydrate metabolism at
the National Institute of Arthritis and Metabolic Diseases in Washington, D.C. From there he went on to become professor and chair of

I

..

internal medicine and director of the first Division of Endocrinology

&lt;

and Metabolism at St. Louis University School of Medicine.

...

20

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UN G ER

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2 000

Compiled by Pamela M. Rose, MLS, Health
Scie11ces Library, U11i1•ersity at Buffalo, 3435
,\1aill St., Buffalo, .''JY 14214-3002; (716)
829-3900, ext. 129; pmrose@acsu.buffalo.edu.

�PATHWAYS

Click Appointed to
Ped"a r·c Surgery Po t
Following a national search,
Philip L. Glick, MD, has been

In Memoriam

appointed surgeon-in-chief at
Kaleida Health's Children 's Hospital of Buffalo, clinical
director of the
Department of
Pediatric Surgical Services
at Kaleida and
division head
of pediatric
surgery in the Department of
General Surgery at the University
at Buffalo's School of Medicine
and Biomedical Sciences.
Glick, a staff member at
Children's Hospital since 1988, is
a professor of surgery, pediatrics
and obstetrics/gynecology at UB,
where he also serves as vice chair
of surgery for research, and training director for the Pediatric
Surgery Residency Program.
A Los Angeles native, Glick
completed his undergraduate

T.

BRONK

education at the University of
California at Berkeley. He graduated from medical school at the
University of California at San
Francisco, where he also completed residencies in general surgery and fetal surgery and served as
chief resident in general surgery.
He was a senior resident and chief
resident in pediatric surgery at the
University of Washington and at
the Children 's Hospital and Regional Medical Center in Seattle.
- S.

A.

UNGER

Summer

2000

Buffalo Ph ysi ci an

21

�PATHWAYS

EDITOR's
NOTE:
1

tH;. JVUVH'J.If.g

are brief
introductions
to faculty

Scott Coffey, PhD

Marc S. Fineberg, MD

1ssi&lt;tatlt Pr.Jte&lt;sc r

Amsta•Jt ( timcal Professor
Depart•nent of Orthopaedic Surgery
c·r.iver&lt;ity at Buffalo Sports
\1edi:i JC Institute

who have
recently
joined the
Universztv at
Buffalo
School of

Coffey joined UB's faculty in
November 1999 as an assistant
professor in the Department of
Psychiatry and is affiliated with the
Community Mental Health Center
at Kaleida Health's Buffalo General
Hospital. He earned his bachelor of
science degree in psychology at

Medicine and

Arizona State University in 1988,

Biomedical

his master's degree from the Uni-

SCiences.

his PhD from the University of

versity of North Texas in 1992 and
Mississippi in 1996. Coffey completed his training at the National
Crime Victims Research and Treatment Center and was a National
Institute on Drug Abuse research
fellow at the Medical University of
South Carolina. Prior to coming to
UB, he was a research associate in
the Department of Rehabilitation
Sciences in the College of Health
Professions at the Medical UniversityofSouth Carolina. His research
interests include drug craving and
impulsivity in substance-dependent
individuals and the treatment of
trauma victims with a comorbid
substance use diagnosis.

Fineberg joined UB's faculty as an

Fineberg's current research

thopaedic surgery in August 1999.

interests include procedural

He is affiliated with the UB Sports

advancements in anterior cruci-

Medicine Institute, with active

ate ligament reconstruction

surgical time spent at Kaleida

through the Cadaveric Arthro-

Health's Buffalo General Hospi-

scopy Teaching Lab; and mag-

tal and Millard Ambulatory Sur-

netic resonance arthrogram

gery Center, and at Erie County

active (MRAA), a new test de-

Medical Center. Fineberg earned

signed to increase diagnostic

a bachelor of science degree in

sensitivity for occult soft-tissue

biology, cum laude, from Syra-

injuries of the shoulder.

cuse University in 1989, and a
medical degree from Northwest-

Paola Muti, MD

ern University Medica l School in

4ssocia te Professor
VepartmetJt of Son a/ and
Preventive .\ledicJtJe
Senior Associate Research Snentist
Research ltJstJtutc 011 4ddJctions

1993. He completed a general
surgery internship at New York
University/Bellevue Hospital
Center in 1994, and a residency in

In july 1999, Muti was appointed

pediatric orthopaedic surgery at

as an associate professor in UB's

Shriner's Hospital for Crippled

Department of Social and Preven-

Children in Tampa, Florida, from

tive Medicine, where from 1995 to

March to April1995 and january

1999 she had served as a research

to February 1997. He was execu-

assistant professor. Currently, she

tive chief resident in orthopaedic

also serves as a senior associate

surgery at New York University/

research scientist in UB's Research

Hospital for joint Diseases from

Institute on Addictions, a position

july 1997 to june 1998, and a clini-

she has held since 1995. Muti
earned a medical degree from

Mun wAs APPOL 1TED AS A • A~sociATE PROFESSOR IN

22

l 1 1fa l o Ph ysici an

Summer

ment of Orthopaedic Surgery
from August 1998 to july 1999.

assistant clinical professor of or-

cal fellow in sports medicine at

TIVE MFDICI E, WHFRF FROM

Massachusetts General Hospital!
Harvard Medical School's Depart-

UB's DEPARTMENT oF

SociAL AND PREVEN-

1995 TO 1999 SHE HAD SERVED AS A RESEARCH ASS ISTANT PROFESSOR.

2000

�University of Pisa in 1984 and a
master of science in epidemiology

Druar Named Recipient
of Naughton Award

Christopher T.
Sempos,PhD

ship in UB 's Department of Social

\ssocrate Professor
Director ot Graduate Stud.
Department of Sacral and
Pn" P&gt;Jt'"p \1 .,, ·

and Preventive Medicine. Her

Sempos joined UB's faculty in No-

from UB in 1993. From 1996 to
1999, she served a Buswell Fellow-

5

named the first recipient of the Naughton

research interests are in cancer

vember 1999 as an associate profes-

epidemiology, specifically hor-

sor and director of graduate studies

monally related cancers, such as

in the Department of Social and

breast and prostate; and in research

Preventive Medicine. He earned a

methodology and biomarkers.

bachelor of arts degree in anthropology from the University of

M.

Matthew Phillips, MD

Wisconsin, Milwaukee, in 1973, and

Cllllrcal Assistant Professor
Department of Ortlropocd•cs

master of science degrees in nutritional services and preventive med-

Phillips joined UB 's facu lty as a

icine/epidemiology at the Univer-

clinical assistant professor of or-

sityofWisconsin, Madison, in 1979

thopaedics in july 1997 and is

and 1982, respectively. He completed

affiliated with Erie

a doctorate in nutrition sciences at

County Medical
Center and Kaleida

Wisconsin in 1982. For more than

Health ' s

Buffalo

Federal Civil Service as a health stat-

General Hospital

istician, during which time he was

(BGH ). He earned

project officer for the Framingham

his bachelor of sci-

and jackson heart studies at the

PHILLIPS

15 years, Sempos worked in the

ence degree, cum

National Heart, Lung and Blood

laude, in chemistry

Institute. He also served as chief of

from St. Lawrence

retary for the Medical Alumni Association

Nancy Druar,

the longitudinal studies branch for

University, in Canton, New York,

the National Health and

in 1987 and his medical degree

Examination Surveys, and assistant

utrition

Award, as announced by dean John R. Wright, MD, on April29,
2000, at this year's Spring Clinical Day and Reunion Week·
end. The new award, established by John Naughton, MD, dean
of the University
at Buffalo School
of Medicine and
Biomedical Sci·
ences from 1976
to 1996, recognizes a nonfaculty
individual who
has made signifi·
cant contribu·
tions

to

the

school. Such an
individual, the
award acknowl·
edges, is one who
"day in and day
out, in his or her
NA NC Y DRUAR
own quiet way,
makes our school,
with its affiliated teaching hospitals, a stronger, healthier
and happier place for the rest of us to learn, work, conduct
research, provide patient care and teach." Druar, who has
served in her current role since 1980, is responsible for

I

.

from UB in 1991. He completed

to the head for the World Health

coordinating the day-to-day operations of the Medical Alumni

an internship in general surgery

Organization Collaborating Centre

Association office, including communications, dues manage-

at UB in 1992 and residency

for Health and Nutrition Examina-

training in orthopaedic surgery

tion Surveys. His current research

ment, financial reporting and budget preparation. In addi·
tion, for the past 19 years she has taken a lead role in planning

at the university in 1996. He

focuses on the relationship of

then served a fellowship in joint

body iron stores to risk of cardio-

replacement and lower-extrem-

vascular disease.

"ambassador for the school" and an individual who through

Krackow, MD, at BGH from 1996

Barbara Stefanick, MD

"kept the vital machinery of the alumni office moving,

to 1997. His clinical interests in-

\ssistant Professor of

Clilllcal Pc,thologr
Dcpartmmt of
Patholo "

advancing the school's mission in ways immeasurable."

clude hip and knee replacements,

ity reconstruction under Kenneth

failed or revised hip and knee

Nomination letters on Druar's behalf referred to her as an
her "intelligence, pleasantness and diligence to her task" has

replacements, lower-extremity
deformity and knee orthoscopy.

the school's annual Spring Clinical Day and Reunion Weekend.

Stefanick, who joined UB 's faculty

Druar received the award at the Annual Faculty Meeting
on May 26, 2000. Other awards presented at the me
be reported on in the fall issue of Buffalo Physiciat

CD

in july 1999, is an attending
pathologist at Kaleida Health 's

S umm e r 2 000

Buffalo Pbys i c i an

23

�PATHWAY

Buffalo General Hospital. She
earned her bachelor of science

Bianca WeinstockCuttman,MD

degree, magna cum laude, in biology from UB in 1990 and her
medical degree, cum laude, from
the university in 1994. She then
completed her residency training
in anatomic and clinical pathology at UB, where she served as
cochief resident from 1998 to
1999. Stefanick is board certified
in anatomic and clinical pathology, and her clinical interests
focus on renal pathology.

Weinstock-Guttman joined UB's
faculty in November 1998 as an
assistant professor of
neurology. Her clinical
affiliations are with
Kaleida Health 's Buffalo General Hospital
and Baird Multiple
Sclerosis Center at
Millard Fillmore Gates
Hospital. WeinstockGuttman earned her

medical degree at the University of

Foundation, where he then served

Bucharest in Romania in 1983. She

an EEG/epilepsy fellowship from

completed a rotating internship at

1996 to 1997. In june I998, he

Carmel Hospital in Haifa, Israel,

completed a pediatric residency

in 1986 and a neurology residency

at Rainbow Babies and Children

at Sapir Medical Center,

Hospital in Cleveland . Wein-

Meir General Hospital,

stock's primary research interest

Kfar-Saba, Tel Aviv Uni-

is in epilepsy, EEG and neuro-

versity, in Israel, in 1992.

physiology. At the Mildred

In 1996, she completed a

)assoy Long-Term Monitoring

three-year Neuroimmun-

Unit, he and his colleagues are

ology Fellowship at the

assessing whether patients could

Mellen Center for Mul-

benefit from epilepsy surgery.

tiple Sclerosis Treatment
and

Research at the

Cleveland Clinic Foundation. At UB, her research and
clinical focus continues to be MS.

Musicians, artists, dancers,
actors, athletes, scholars ...
we all love Nichols.
• State of the art visual and
performing arts center
• Exceptional college
placement record

Prot s &gt;r

p

a d

'\/ ,r 'PI

~' '-'' I a

t

n

Wilkinson, who joined UB's Department of Social and Preventive
Medicine in May 1998, also serves
as a professor in UB's Department of Oral Diagnostic Sciences,

Weinstock joined UB's faculty in

in the School of Dental Medicine.

August 1998 as an assistant pro-

Prior to coming to UB, he was an

fessor in neurology and director

adjunct professor in the Depart-

of pediatric epilepsy and neuro-

ment ofEpidem iology at the School

physiology. He is affiliated with

of

Kaleida Health's Children's Hos-

at Albany. Wilkinson earned his

• Comprehensive community
service program

pital of Buffalo, where he is

bachelor's degree in 1969, his

director of the Mildred jassoy

master's degree in 1971 and his

• More than 60 sports teams

Long-Term Monitoring Unit.

PhD in 1973, all from UB. He com-

• Average class size of 15

Weinstock completed a rotating

pleted a postdoctoral research

• Financial aid available

internship at Carmel Hospital in

training fellowship at Duke Uni -

Haifa, Israel, in 1986, and a pedi -

versity Medical Center in Durham,

atric residency at Hasharon

North Carolina. At UB, his research

Coeducational grades 5·12

875-8212
1250 Amherst Street
Buffalo, NY 14216
www.nicholsnet.net

Acceptance granted to qualified students
without regard to race, color, religion or
national origin.

laffalo Pbysician

\/(flit

I r ct r Jfl'ctlu, r1c tp1

rotcs&lt;"
JCpartmcllt

• Challenging curriculum with 17
advanced placement courses

Only one inveslrnenl
lasrs a lifetime

24

Arie L. Weinstock, MD

Cregg S. Wilkinson,
PhD

5

u 111 m e r

2 0 0 0

Public

Health,

SUNY

Hospital and Tel-Aviv

interests include the ef-

University, from 1987 to

fects of low-dose radia-

1992. From 1993 to 1996,

tion, and cancer induc-

he served a pediatric

tion related to environ -

neurology fellowship at

mental and occupational

the Cleveland Clinic

exposures.

CD

�- - - - - - - - - - - - - - - - - - - - - - - - - - - --- - -

--~

--

~- --

the 63rd
April29

2000

ACall to Physicians to Lend Their Voices
Children's health in the new millennium
BY jENNIFER LEWANDOWSKI AND

s. A.

UNGER

Opportunities and Challenges," at the University at
Buffalo's 63rd annual Spring Clinical Day held
April 29, 2000, at the Buffalo-Niagara Marriott in
Amherst, New York. The weekend event, which
explored the theme "Children's Health Issues," was
sponsored by the UB Medical Alumni Association.
Hayes, the assistant secretary of Community and
Family Health for the Washington State Department of
Health, urged physicians to view the advent of a new
decade and new millennium as an auspicious time to
more proactively advocate for an improvement
in children's health in our country.
" It begins with a fresh commitment from each

Pictured,
letr. Maxine
Hayes. MD
'73. delivered
Stockton
Kimball
Lecture.

of us as individuals, wherever we are stationed, to
be willing to move out of our comfort zone and
get involved as advocates for children and their
families," Hayes implored. "It might start with a
small gesture: a telephone call to a powerful
political figure, a letter to the editor of a newspaper, a talk

at a PTA group, a testimony before a health committee

..•

.
I

MAGINE A NATION in which the child poverty
rate is the highest in the industrialized world .
Imagine a nation in which social conditions are bringing about a rapid increase in youth depression, a nation
in which children as young as preschool-age are being

of a state legislature, a contribution to a child advocacy
group, or through mentorship of a medical student.
"We can all find ways to use the clout we have as
physicians and stand up for children," she added, stressing
that now is the time to reflect and focus on children, as "they
do beautifully symbolize the promise of the 21st century."

prescribed such antidepressants as Prozacand such stimulants as Ritalin.
Imagine a nation in which youth in the fastest growing segments of the population are at the greatest risk for

Hayes began her overview of the status of children's

poor health status and care.
The nation is the United States, and the challenges are

health by presenting a historical survey of the development of medicine over the past millennium, highlight-

growing exponentially, according to Maxine Hayes,

ing the many strides made in health care, especially in the

MD '73, who delivered the keynote lecture titled "The

area of public health. From there, she turned her atten-

Future of Children's Health in the New Millennium:

tion to issues prevalent in the 21st century that threaten

S 11mm e r

2 000

I u f fa I o Physician

25

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our children, and ways in which physicians can take a leadership role

function of America's families are also directly impacting children's

in confronting these issues.
Because chronic disease has supplanted acute illness as the pri-

substantially more likely to have a family income below poverty than

health. "Children who live in a household with one parent are

mary threat to children's health, physicians who treat children today

children with two parents," she reported. "In 1998, nearly 25 percent

are faced with different challenges than were their counterparts in

of children lived only with their mother and, today, more children

the recent past, Hayes explained. Referencing data from the National

live in step, blended, sequential or foster families, and many more

Health Interview Survey on Disability, she reported that 15 to 18

are homeless." In all, "child poverty in the United States has nearly
doubled since the 1960s," she stated.

percent of all children today have "ongoing developmental, physical
or mental problems that affect their functioning or that require
compensatory services for maintenance of a functional level." These

To this mix of social changes affecting our children must be added
the fact that racial and ethnic diversity has grown dramatically in the

conditions, she explained, range from such common diagnoses as

United States over the past 30 years, noted Hayes, who predicted that,

attention deficit hyperactivity disorder to severe psychiatric disor-

after the 2000 census, "we will see a continuation of this trend."

ders. "Assuring children's mental health and emotional well-being

According to the Children's Defense Fund, Hayes said, minority
children now make up 30 percent o f t h e populatiOn
.
under age 19,

will challenge us in the new millennium," she said.
Of special concern, she noted, is a rise in the reported incidence

and by the year 2020, racial and ethnic minority children will make

of depression in children, an increase she attributed to

up 40 percent of the population under age 19. "Because minority

"fHF BO.rOM

the many "rapidly changing social conditions" encoun-

chtldren are more likely to be poor than their non-Hispanic, white

L,'&lt;E IS "!HAT

tered by today's youth.
Hayes described a recent study of8,000 Americans 15

counterparts, they are often at risk of poor health status" she said.
"And these
children ca 11 no t b e ·tgnore d , as t h ey are fast becommg
'
. the
.

PHYSIC lA "''&gt;DO

to 54 years of age in which only 2 percent of those age 45

HAVF ( lOl T.

to 54 reported symptoms of clinical depression by their

emergmg maJ·ority upon wh'IC h th.ts natiOns
· , contmumg
. . prospenty
.
and future will rest."

late teens, while among 15- to 24-year-olds, 23 percent
THE PROBLE~I

reported serious depression before age 20. Furthermore,

roo

she said, teachers and pediatricians are documenting

I&lt;; fHAT

more depressed youngsters than in the past.
MANY 0~ U

1-AI ... lO l &lt;;tIT."

Among the "rapidly changing social conditions" that
contribute to depression, Hayes said, are alterations in
family structure, increased mobility of families and un-

stinting exposure to global violence and unrest through television
and the Internet.
"With the click of a mouse, children can view graphic worldwide
calamity and suffering," which causes increased levels of anxiety and

Physicians today , Hayes sat·d , can h e1p counter these dtsturbmg
.
.
trends in children's he a lth b Yb ecommg
· .mvolved tn
. one or more of
the following four are nas.. po 1·tcy, practice,
. research, and educatton
.
and training
.
.
· With regard to po 1·tcy, s h e sat'd" strong mvestments
111
.
preventton are key to assuring child health," emphasizing that "these
mvestments
are no 1anger a 1uxury or even a chotce."
.
.
An example of
such an mvestment 1·11 preventiOn,
·
. ts
. the Chtldren's
.
s h e satd,
Health
Insurance Progran1 , w h.IC h sh e encouraged phystctans
..
to become

Compounding the problem of overexposure to calamitous news

aware of and supp or t tn
· t h etr
· respecttve
. states.
In terms of practice and education, Hayes candidly told her
audtence that "changt'ngde mograp h.tcs means we must d'tverst·ry our

is the fact that many children today aren't provided with "the

provider work force. We need practicing providers who are not only

depression, she said. "As citizens of a global village, they are far less
protected from worrying than children were in years past."

anchors, the emotional support, they used to have growing up,"

tram~d 111 technical skills but culturally competent, as well."

ow is

divorce currently affects more than 1 million children in the U.S.,

the time, she said, for us to address the "- isms" in medicine-the
"racism and se xtsm
·
th at create barners
.
to mutual respect and
understand'mg. "Reterencmg
c
·
the February 25 New England Journal

and, at any one time in our country, some 500,000 children are in

of Medicine editorial that addressed this problem in medicine as it

foster homes, circumstances that further erode their emotional

relates to gross inequities in the distribution of care, she added, "As

support base and contribute significantly to depression.

physicians, we need to acknowledge the role we ourselves play in
closmg the gap in health disparities."

Hayes explained. This is because children aren't spending nearly as
much time with their parents as they did three decades ago. Also,

Children are less "anchored" not only in a figurative sense, but in a
literal sense, as well, because their families are relocating more fre-

ln concluding, Hayes reiterated that, "As physicians, we have a

quently, according to Hayes. Thirty years ago, children lived in one place

umque opportunity today to make a difference for our children and
for future gener a t"tons. sorne o f you may say ' I don ' t take care o f

for an average of 21 years, a number that today has shrunk to seven.
Hayes further explained that rapid changes in the structure and

26

The Badly Needed Clout of Physicians

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CONTINUED ON PACE 28

�Medical Alumni lifetime Achievement Awards
Honoring alumni for their outstand i ng contributions

ach year at Spring Clinical Day and Reunion Weekend, medical alumni achievement awards are presented
to graduates of the University at Buffalo's School of Med1cme and Biomedical Sciences who have made
significant contributions to their fields. Recipients are nominated by their fellow alumni, with final selections
made by the governing board of the Medical Alumni Association. This year's recipients are as follow:

Richard H. Adler, MD '45

D . ..Jackson Coleman, MD 'GO
ISO

.. J.:c.ltl~wana ac&lt;"CP _d 1 / Dr GcoriC Ellis
For Dr. Richard H. Adler, former director of the Cardiothoracic
Surgery Residency Program at UB's School of Medicine and Biomedical Sciences, receiving the Medical Alumni Lifetime Achievement Award represented "a valued gift from this fine medical
institution" that launched and helped foster Adler's medical career,
said Dr. George Ellis, who spoke of his friend's achievements
and character.
It was through his education at UB that Adler was given the
opportunity to build on his medical knowledge at various institutions throughout the country and world, experience that prepared
him for his return in 1949 to UB, where he served on the faculty until
1986, Ellis said.
Perhaps the most notable experience for Adler, who also served
as head of the Division of Thoracic Surgery at Buffalo General
Hospital until 1986, was working in conjunction with his students
and house physicians, who continuously stimulated his growth in
medicine, Ellis said, adding that it was through his tenure at UB
that Adler has been able to influence the next generation of UB
students. In 1982-83, this service was recognized at UB, when Adler
received the Louis and Ruth A. Siegel Distinguished Teaching
Award with Honors.
In all his work, he has been a staunch advocate of the clinician
fulfilling the role of a caring provider, something he encourages his

"

Calling Dr. D. jackson Coleman a pioneer in ultrasonography and

"

ophthalmology, Dr. Thomas). Guttuso credited Coleman with discoveries that have increased the ability of ophthalmologists to ana-

•

lyze previously undiscovered diseases.
"He is now a professor and chairman of
ophthalmology at Cornell Medical College," Guttuso said. "He has won nine national awards and fellowships and he is
credited with six inventions," he added,
including an ultrasonically vibrated surgical knife, an apparatus for medicinally
spraying an eyeball and a method for enhancing ultrasonic image data.
In addition, Coleman has written some
56 book chapters, as well as a book titled

Ultrasonography of the Eye and Orbit. He has
also authored 120 publications, in 70 of which
he is the first author, Guttuso said. As a visiting professor, Coleman
has presented 16lectures throughout the United States and Canada,
largely on the subject of ocular trauma.
Coleman serves on the editorial boards oftheA11nals ofOphthal-

mology and RETINA. In addition to being a diplomate of the
American Board of Ophthalmology, he is a fellow of the American
College of Surgeons and of the American Academy of Ophthalmol-

younger colleagues to emulate, Ellis said. Adler believes wholeheartedly that "being a caring clinician and earning the trust and respect
of a patient, is a cherished gift," Ellis concluded.

CoNTINUED ON PAGE 2s

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er 2 00 0

Buff a I o Physician

21

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ogy. He also has served as president of the ew York Hospital
Medical Board and on the Executive Faculty Committee at Cornell
University Medical College.
"He has contributed significantly, not only to his field, but to
the knowledge of medicine everywhere," Guttuso said. "He is
certainly the star of our class."

Anil B. Mukherjee, MD '75

[.... vducec.

Wl&lt;.

l.Ccep.cJ !J/ Dr.

/urw

s,ztbenlwrd

A friend of Dr. A nil B. Mukherjee's since their early days of medical
school in 1972, Dr. john Stubenbord explained that, after graduation from the UniversityofCalcutta in 1962, Mukherjee came to the
United States, where he completed master's and doctoral degrees at
the University of Utah. He then earned his medical degree from the

N . Lynn Eckhert, MD '70

University at Buffalo 1975.
After medical school, Mukherjee completed his residency training

Jmnd ta t b; her broclnr, Dr. Kenneth H. Eckhert

in internal medicine at Georgetown University, and in neonatal and
"It's a privilege and honor to present this award to my sister," said Dr.

a

Kenneth H. Eckhert, who chronicled Dr. N. Lynn

•

pediatric medicine at the National Institute of Child Health and
Human Development and at the ational Insti-

Eckhert's achievements as a medical practitioner.
After finishing medical
school, Dr. Lynn Eckhert

tutes of Health's Clinical Center in Bethesda, MD.
Serving first as the senior investigator of the

In all his work,

pregnancy research branch of the NICHD and

completed an internship at
the Cleveland Clinic, said

has been astaunch

the NIH, then as chief of the section on molecu-

advocate of the clinician

lar and developmental genetics in the pregnancy

her brother, himself a 1968

fulfilling the role of acaring

branch, Mukherjee is currently chief of the sec-

provider, something he

tion on developmental genetics in the human

graduate of UB. Shortly
thereafter, she was married
"to a wonderful physician

encourages his younger

genetics branch of the TCHD.
Mukherjee, who served a brief stint as an

who was studying at

colleagues to emulate, Ellis

assistant professor of pediatrics and human ge-

Children's Hospital of

said. Alder believes whole·

netics at UB in the late 1960s and early 1970s, has

Buffalo" and whose work

heartedly that "being a

also written hundreds of papers on genetics,

with the Peace Corps took
them to Oklahoma.
"Lynn then took a residency in pediatrics at the
University of Oklahoma, and from there she went

"most of which I couldn't possibly understand,"

caring clinician and earning

joked Stubenbord.

the trust and respect of a

Concluding, Stubenbord said he was hon-

patient is acherished gift."

ored to speak on behalf ofM ukherjee. "Ani! is a

on to johns Hopkins University, where she became

good friend, and I feel privileged to accept the

I

a Robert Wood johnson Clinical Scholar and re-

award for him," he said.

ceived her second master's degree-a master's in
public health-in 1973," he said. Seven years later, she completed
a doctoral degree in public health from johns Hopkins University.

"A

CALL TO

PHYSICIANS"

FROM

PAGE

26

In 1984, she was named chair of the Department of Family and

children,' or 'I am retired,' or ' I take care of children, but my practice

Community Medicine at the University of Massachusetts Medical

doesn 't involve children who are disadvantaged.' Others might say, 'I

Center and, in 1991, codirector of the MPH Program at the

am empathetic ... but I don't think I can do anythingaboutanyofthis.'

university's Amherst School of Public Health.
In the early 1990s, she served for one year as a visiting professor

that too many of us fail to use it. It is true that most children in our

"The bottom line is that physicians do have clout. The problem is

in the Department of Community Medicine at the University of

nation are in good health and have loving parents who tend diligently

Zimbabwe and another year as visiting professor in the Department

to their physical, intellectual and spiritual needs. But we live in an

of Pediatrics at the University of Capetown. In 1994, she was named

interdependent world and our destiny ... depends as much on

Project HOPE's first William Walsh International Health chair.

youngsters who are unhealthy, poor and alienated as on those who are

cellor and dean of the International and Public Health Programs at

more advantaged.
"We can all find ways to use the clout we have and to stand up for

the University of Massachusetts Medical Center.

children," Hayes concluded. "They are depending on our voices.

In 1997, she was appointed to her current position of vice chan-

They are depending on us."

28

CONTINUED

I u If a I o Ph ysici an

Summer

2000

4D

�I

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~~--

~

------------+~~----

FIRST ROW: ROBERT j. PATTERSON. V\ILLIAM S.
WEBSTER, LEO ~~~NNING, ADELMO 0UNGHE, HELEN
f. SIKORSKI: SECOND ROW: GEORGE TAYLOR, ROY
'\&lt;\'.ROBINSON, CARLA. CECILIA, RICHARD.).
LEBERER, HY\IA:-1 TETEWSKY. ROBERT BERG.'ER,
KARL MANDERS, WILLIA\1 STEIN. YALE SOLO\!ON,
ROLAND ANTHONE: THIRD ROW: HENRY

L.

PECH,

SIDNEY ANTHON E. ROBERT,'. Ku.·G. RICHARD
LYONS

ROBERT BENNINGER, GUYS. ALFANO,

EuGENE.).

LEFT TO RIGHT: ALBERT

C.

REKATE

lYGAJ. jAMES Du.·N. Do:-~ALD THO\I~S.

WARREN R.

\!0:-&lt;TGOMERY, jOHN G. 7.0LL, WILLIA\1 HILDEBRAND,
j HIES

P.

SCHAUS.

FIRST ROW: WINIFRED MERXA:-1, CLEORA K.
KEELEY, jOHN H. PETERSON, C. DANIEL
FAGERSTROM: SECOND ROW: S. JOSEPH
LA\1ANCUSA, LAWRENCE

f. BEAHAN . .)OHX H.

KENT, fRANK.). GAZZO, ALBERT A. FRANCO.
RAY G. SCHIFERLE, jOHN B. BAKER.

FIRST ROW: HERBERT

E. JOYCE,

A. ARTHUR GRABAU,

GE:O.:EVIEVE G. HOWEN. EARL K. CANTWELL
ROBINSON, CHARLES

E.

JOHN G.

WILES; SECOND ROW: "lORMAN

GHASSIN, JOHN f. HARTMAN. WILLIA'.I S. ANDALORO, WAYNE
G. Tn!PLER, IvAN W. KuHL, WILLIAM'\. MciNTOSH: THIRD

ROW: K. jOSEPH SHEEDY. GEORGE M. ELLIS. jACOB

S1

EINHART: FOURTH ROW: ROBERT

l.AGLIA. GEORGE THORNGATE.

IV.

C.

.\1.

SCHOPP, \'ITO

P.
Summer

2000

laffala Physician

29

�SuMMER

2000

FIRST ROW : IRWIN STEINBERG, WILLIAM E. ABRAMSON; SECOND
ROW : jOSEPH A. CHAZAN, EDWARDj. GRABER, fRANKLIN
GLOCKNER. jAMES R. KANSKI, ROGERS. DAYER, SYLVIA
SussMAN, HARRIS C. fAIGEL: THIRD ROW : jOSEPH C.
&gt;\NTKOWIAK, DANIEL A. GOLDBERG, H ARR I S ~.KENNER,

L. LEITER,

MARSHALL A. LICHT\IAN. ANDRE D. LASCAR!, NAOMI

ALGIRDAS CAMZIUKAS, DONALDj. DONIUS. WILLIAMj. STEIN,
DO!'iALD A. HA\O.IEL, D. jACKSON COLEMAN' GERALD
DIESFIELD, EDWIN R. LAMM, EUGENE T. PARTRIDGE; FOURTH

ROW : fRANCISj. KLOCKE. HARRY

L.

METCALF. DANIEL T.

GIA!'o&lt;TURCO. THO\I ASj. GUTTUSO, THEODORE S. BISTANY,
ROBERT T. GUELCHER. ROBERT

L. ~ALATESTA,

DAV I D'\.

FIRST ROW : SULAH MEGAHED, ALAN M. PODOSEK, STEVEN
V. GRAB I EC, ALANj. f i NK, N. LYNN ECKHERT, LAURENCE

:-...1.

LESSER, WILLIAM f. BALISTRER I , D.H'IDj. ROSSMAN,

AGNES

\ I ESCHES.

V.

SZEKERES, DONALD

SECOND ROW: HENRY

L.

P. COPLEY, jOHN D. fOLEY;

WHITED, ARTHUR R. GOSHIN.

THOMAS A. O'CONNOR, SHAFIC Y . TWAL, WILLIAM j.
fiDEN, \ I ICHAEL

FIRST ROW : ARTHUR

M.

L. LIPPMAN!'i, jA:-i

~-NOVAK.

MORRIS, LANCE fOGAN, IRA

HINDEN, SECOND ROW : jOSEPH G. CARDA~IONE, GEORGE B.

~OORE, GARY H. JEFFERY, GEORGES. STRAUSS,

H.

ELLIOTT

LARSON, BENJAMIN j. WHERLEY. !1-frCHAEL S. FEINBERG.
AUGUST

J.

D'ALESSANDRO.

FIRST ROW: DAVID KLUG, LEO R. ~UIDO, \1ARY ELIZABETH
ROEHMHOLDT, ~ ARGUERITE DYNSKI, LYKNE HOCHBERG PACE,
BRENDAN C. BRADY; SECOND ROW: PAUL D. TRAUTMAN, HENRY
P. TOMIAK, DENNIS C. WHITEHEAD, LAWRESCE C. MILLHOFER,
WILLIAM I. COHEN, LUDWIG LICCIARDI, jACK
CUKIERMAN, ~ARC

30

lullalt Hysician

SummL'r

2000

F.

P. fREER, jACK

COLMA!&gt;, jOHN H. HEDGER, jOHN C.

STUBENBORD, jOHN LOVECCHIO.

�----- -----

----~~~~~------------

---~

- - - - - ~--

FIRST ROW : MATTHEW G . SALTARELLI. MARC K.
KLEME~TOWSKI. GALE BURSTEIN BL00\1, ~1ICHAEL B.

MARINO, !\'IZA:\1 RAZACK, ANN RIZZO; SECOND ROW : PETER
BLOOM. LIDIA V. WENZ, NGOZI 0SUAGWU, EILEEN

M.

SALTARELLI, VALERIE VULLO SAENGER, MICHAEL LICATA,
RAYMOND V. PAOLINI. LAURA
PANEBIANCO, jOYCE
jANICE

E.

N.

J.

NICHOLSON. STEPHEN M.

PATERSON, ALICE PIEN MILGROM.

ERRICK, SHOBHINA G. CHHEDA. SuzzETTE

N.

ROBINSO'I, STEVEN j. HOWARD. DENISE ALOISIO, VIRGINIA
FIRST ROW : BARRY A. CLARK, ROBERT SHALWITZ. PETER H.
GREENMAN. MARK S. BORER, EvA KLO~OWSKI, LYNN

\1.

E. ROBERTSON; TH IRD ROW : PETER WINKELSTEIN. EDWARD
F. KOWALSKI, ROBERT j. LEON. SEAN CAO, RAGHU RAM,

l.

STEINBRENNER, fRANK W. SANCHEZ, THOMAS DOUGHERTY;

HOWARD

SECOND ROW: ~! ARGARET W. PAROSK I , CONSTANCE B.

LIVERPOOL. GREGORY D. SA:&gt;.!BUCHI . RA:-.:JAN BHAYAI'&lt;A.

STOLL, MICHAEL HAYMAN, STEVEN F.

LE:-.:Tz, THERESA STEPHAN HAil'S, EDWARDj. ROCKWOOD.

LEFT T O RIGH T: KAREN E. DULL, TRACIE DIMARCO, MARTIN
C. :v!AHONEY. TARA SOSA PAOLINI. PATRICIA A. KREBS.
STEVEN M. FINKELSTEIN, GARY j. 'l!ELAN, DANIELLE
NOTEBAERT FEELEY, ARAVIND HERLE, KATE GUERNSEY
ACKERMAN. MIROSLAV P. BOBEK. GREGORY A. MCDANIEL.

F I RST ROW : ELIZABETH

l.

MAHER. C. ADRIANA ALVAREZ,

LUCIE A. DIMAGG I O, ELIZABETH SPATOLA; SECOND ROW :
LOU ANI\ GART:-;ER,jOSEPH A. ZIZZI, RAYMONDj. MEEKS,
CAROL HAMMER FORSTER, MARGARET E. REIDY, SHIRLEY V.
GALUCKI, BARBARA P. UPPAL. ELAI:o.;E SCHAAF, LAUREL A.

\1. STIDHAM; THIRD ROW : THOMAS B.
~1ICHAEL P. NANCOLLAS. CARLj. TURTSS I !\1.

PFEIL. LY:\DA
COWAN,

IRA S.

HANDLER, jACK F. COYNE, DAVIDj. FoRSTER. DoNALD
TINGLEY. jOHN LEDDY, jAMES M. ESSER. jOHN R. FUDYMAN,
M I CHAEL LAHOOD, DALE W. SPONAUGLE.

Spri11g

2000

lufl al 1 Physicia n

31

�0

E

V

E

L

0

P

M

E

N

T

N

E

s

w

Tomorrow's Traditions Be ·nToda
By Li nda J . Cor de r , Ph0, CFRE
of memory and hope.

region, joined with the medical school as official spon-

extends back through the generations to a small group of

sors of the Mini-Medical School for the next ten years.

Buffalo citizens, primarily physicians and attorneys, who

This is the third year that UB has participated in the

founded the University in 1846. Their dreams included

White Coat Ceremony. One ofouralumni, Don Pachuta,

awarding degrees in all fields, being nonsectarian in governance, and training professionals to serve their region.

History of Medicine at the University of Maryland, real-

Ourcommunitynowextends to all states and throughout the world, where physicians, surgeons and scientists

minds and hearts of future doctors, so initiated an en-

institutions-labor in hope, providing tools for lifelong
learning, nurturing curiosity and humanity.

inaugural lecture himself. Both events reinforce that
medicine is an art and that healing often has more to do

The mission of the development staff is to serve as a

with authentic communication between human beings

catalyst to deepen and expand this noble endeavor. Our
work complements that of faculty and administrators and

than with the latest technology or complex equipment.
In the fall, the Pathology Department will initiate a
lecture in memory of Dr. Kornel Terplan, who earned
an international reputation for his research in the areas

professors and to express their appreciation for the educa-

of tuberculosis and neonatal neuropathology.

•.. \I E ll I C I -.; I

much as possible about the dreams and
priorities for the

sons initiated the endowment, with the reminder that

\1 0 R E T 0
~

T IC

B E T \\" E E :\

\\"\T\1

32

0 F T I \:
\) 0

school's future.

"although educational content and educational tools

We listen to

will change from century to century, the need to

the stories of

develop healthy minds, healthy bodies and a healthy

alumni

and

environment will not change. We will always require

friends, seeking

disciplined scholarship, hard work, honesty, humility,

C 0 .\1 \I L '.; I C. AT I 0

I A"\ EST

C 0 \t P L E X

I u I I a I o Phys ician

~

T II ·\ :"'

TEl 11:-:01E Q L I P \I 1- ;-,: T .

S11mmer

humor and skepticism of the unproven . .. "
On a final note, the first annual

aughton Award

to help the school realize

was presented at the annual faculty meeting on

its vision. Then, we en-

May 24, 2000. This endowed award-established by
Dr. john aughton for the "unsung heroes" of our

This spring, Dr. Harry

RT
II A S

\1 I T H

H U :\t A ;\ B F I ' (, S

TilE

0 R

~

I S A :-;

H \· A I I :-; &lt;;

Dr. Terplan served our school and that department as
chair for over three decades, and even those of us who
never met him feel his presence in our community. His

able them to "just do it."

0 GY

Physician." This August, Dr. Pachuta will deliver the

and friends an opportunity to "give back," to honor former

finding those who want

L T H I

dowment to ensure that the tradition will be ongoing. He

enhances the students' experiences. It also provides alumni

common threads,

~

ized the personal importance of this ceremony in the

also made provision for a special lecture for returning
second-year students, with the theme "Dear and Glorious

Development officers are matchmakers. We learn as

:-; ll

who served for many years as professor of Ethics and the

use skills and knowledge they learned in Buffalo. Our
immediate community, those who study, conduct research, guide grand rounds, and otherwise work within
the school's walls-and in its network of affiliated

tion and opportunities they received from the school.

.~

known for their support of activities that enrich our

Our community transcends both time and distance. It

school-is described in detail on page 23.

Sultz, founder of our

Thus do the values in the school's collective memory

Mini-Medical School,

become the foundation of its future hope. Together, mem-

was honored in a special

bers of our unique community facilitate that process. 4D

"Health Care Heroes"
issue of Business First. At
about the same time,
Don and Esther Davis,

Lyn Corder is associate dean and director of development.
Slzemaybereachedbyplwne, tollfree,at l-877-826-3246,or
by e-mail at ljcorder@buffalo.edu.

2000

�Dear Fellow Alumni,
F\\t&gt;lhiiJT

T!H

~

A ""r)r I\ rrn

\Jfri)(Af A11

I would first like to

thank our outgoing president, Dr. Richard L. Collins, for the outstanding job he has done in
leading our organization. Dr. Collins was successful in solidifying two wonderful programs
during his tenure: The first was the Physician-Student Mento ring Program, which has become
a huge success. The second was the White Coat Ceremony, in which first-year students are given
their clinical white coats on the first day of their orientation to medical school; this is done in
the presence of their families and many of the faculty members.
On April 29, 2000, we held our annual Spring Clinical Day at the BuffaloNiagara Marriott. The program was titled "Children 's Health Issues," and our
keynote lecture, delivered by Maxine Hayes, MD '73, addressed the future of
children's health in the new millennium. For a report on this insightful and
informative lecture, l refer you to page 25 of this issue of Buffalo Physician.
This year, we plan on continuing all of the programs that have been offered to both the
alumni and the medical students in the past. I would, however, like to focus on membership in
the Medical Alumni Association. I know how valuable a physician's time is. Nevertheless, l do
feel that as our university continues to make great strides in the medical community, our alumni
association should be matching those strides step for step. We need to have a strong base of
alumni-not only our older graduates, but also our recent graduates-to support the school in
every way possible. We offer a lifetime membership that is very economical, especially for
younger doctors who plan on being in the alumni association for the next two to 30 years. Our
lifetime membership is also a way for older physicians who are in a more stable situation to
support the alumni association and its programs. You 'll be hearing more from me in the fall
about increasing our membership and the percentage of alumni who become lifetime members.
If any alumni have ideas they wish to share or would like to volunteer their time to help
with the association, please contact me at (716) 829-2778. !look forward to this upcoming year
as one in which our association will grow and prosper.

President, Medical Alumni Association

5

11 111 111

er 2 00 0

Bu If a I o Physician

33

�CLASS

1940s
Edward Tracy, MD '43,

writes: "I enjoy Buffalo
Physician. It's good to
hear about classmates,
etc. I have been married
57 years to the same
"Chick" (that's her nickname!) and we have
seven children, all of
whom are married. Two
graduated from West
Point Military Academy
and two from The Citadel. Three of my daughters were educated in
France. We have 15
grandchildren and one
great-grandchild. I am
still very active in private
practice-internal medicine-and teach, pro
bono, at the Medical
University of South
Carolina. The best to all
of you, especially my
classmates."

1960s
Joseph A.Chazan,
MD '&amp;D. received Univer-

sity at
Buffalo's
Distinguished
Alumni
Award
at the
Alumni
Association's annual
awards dinner on April 7,
2000. Chazen is founder
of the Rhode Island Di-

NOTES

active in many civic,
religious and arts
organizations. He has
served for nearly a decade
on the UB School of
Medicine and Biomedical
Sciences alumni board
and is a former chairman
of UB's general alumni
fund drive.
Michael E. Cohen,
MD '61, received the

Samuel Capan Award at
UB's annual Alumni
Association's awards
dinner on April 7, 2000.
Cohen is professor of
pediatrics and neurology and
former
chair of
the UB's
Department of
eurology, received the Samuel P.
Capen Award-the
alumni association's
most prestigious prizeon April 7, 2000. The
award is presented for
notable and meritorious
contributions to the
university and its family.
Director of pediatric
neurology at Kaleida
Health System's
Children's Hospital of
Buffalo since 1978,
Cohen and his UB colleague, Patricia Duffner,
MD, coauthored the

alysis Program and medical director of the Rhode
Island Artificial Kidney
Centers. He has made
significant contributions
to his community and is

34

lu ffalo

Pbysician

Wels Receives Chancellor Charles Norton Medal
Philip B. Wels, MD '41,

visionary and dedicated

Biomedical Sciences,

received the Chancellor

benefactors of time,

the Medical Alumni

Charles P. Norton

energy, ideas and

Association's

Medal-University at

key funding. A uni-

Achievement

Buffalo's highest

versity Founder and

Award and the

honor-on May 14,

trustee of the UB

Chancellor Capen
Award. In 1997,

2000, during UB's 154th

Foundation, Inc.,

general commencement.

Wels has been the

he was awarded

Wels, who is Professor

recipient of many

the President's

Emeritus of Surgery and

awards from UB,

Chair Emeritus of the

including the Distin-

than 60 years of ongo-

Medal for more

University at Buffalo

guished Alumni Award,

ing service to the UB

Council, has long served

the Dean's Award in the

community.

UB as one of its most

School of Medicine and

highly regarded textbook Brain Tumors in

ties, including chair of
the Tissue Committee
and Representative of
Private Practice to the
Executive Committee.
He is also a clinical
associate professor of
surgery at UB's School
of Medicine and

Western ew York for
25 years and is currently
a member of Advanced
Cardiac Surgical
Associates, PLLC, a
Buffalo-based
practice group.

Biomedical Sciences.

1970s

Children: Principles of
Diagnosis and Treatment, now in its second
edition. A member of
the medical-school faculty since I 968, Cohen
also serves on the Dean's
Advisory Council.
Joseph R. Gerbasi, MD '62,

was honored by the Erie
County Medical
Center's (ECMC) Lifeline Foundation at its
Springfest 2000 annual
black-tie dinner on
April 15. Gerbasi has
been the surgical director of transplantation at
ECMC since 1969 and
has served the medical
center in many capaci-

BP

Areta Kowai·Yern, MD '72,
Ross L. Guarino, MD '66,

was installed as the new
president of the Medical
Society of the County of
Erie on May 9, 2000.
Guarino,
who
succeeds
Datta G.
Wagle,
MD, has
practiced
cardiovascular and
thoracic surgery in

writes:"[ have taken a
position as burn research
director and tissue bank
director at Cook County
Hospital, Department of
Trauma, Burn Center,
Chicago, IL."
Gordon Avery. MD '74.

McLean, VA, Orthopedic Surgery. "I have been
an FL team physician
for the past five years
with the Washington

assnotes
S " '" m e r

2 0 0 0

�Redskins. I am past
president of the County
Medical Society."

the Community Workshop. Please say 'hi' to
everyone for us."

John and Kathleen Braico,
MD '74, Queensbury, NY,

Richard J. Goldberg, MD
'74, writes: "I'm cur-

Pediatrics. "We have
been happily married for
nearly 28 years and have
built a successful group
practice (five pediatricians and two nurse
practitioners). John does
general pediatrics as well
as neurodevelopmental
evaluations for kids with
learning disabilities and
has greatly helped their
educational success. We
are raising two healthy
boys. Besides our prac-

rently professor of psychiatry and medicine at
Brown University, and
psychiatrist-in-chief at
Rhode Island Hospital
and The Miriam Hospital. Recent new events
include starting as editor of the Brown Geriatric Psychopharmacology
Update. Also, I'm halfway through a two
year master's degree
program in medical
management at
Harvard University."
rjgoldberg@lifespan.org

E-mai

nity Health of the University of Massachusetts
Medical School, Worcester, MA. l have a clinical
practice at a community
health center in Worcester." E-mail address is
Lasserd@ummhc.org

Eric Russell, MD '74, Chi-

cago, !L, Neuroradiology.
"I was elected president of
the American Society of
Neuroradiology, 19992000. I am professor of
radiology at orthwestern University Medical
School and director of

neuroradiology at
Northwestern Memorial Hospital. l have
published over 100
scientific publications/
book chapters."
erussell@nwu.edu

~NTIN U ED

ON PAGE 37

J. Manzella, MD '74, York,

PA, Internal Medicine.
"We take care of approximately 250 HIV
patients." lf-jmanzella@

AGenerous Gift of Suppon

yorkhospital.edu
Diane Matuszak. MD '74,

Columbia, MD, Preventive Medicine. "!have
served as a local health
officer ( 1982-1984) and
as a state public health
official for the past 14
years in the Maryland
Department of Health
and Mental Hygiene."
Summerr@compuserve.com

will provide a renewable
tuition scholarship for at
least one student in each

Sanford Pleskow, MD '74,

tice, we are both instructors for neonatal resuscitation. Kathy is a
pediatric advanced life
support instructor, and
for six years she has been
medical director of the
Hole in the Woods
Ranch camp for children with serious and
chronic illnesses. She
participates in an annual
medical mission to Gua temala. John has been
on the board of Head
Start for 20 years, and
Kathy is on the board of

Howard Goldstein. MD '74.

Cherry Hill, NJ, Adult
and Pediatric Urology.
"Children: Lee is a
junior at Yale Medical
School; Lauren is a
sophomore at Columbia
University; and Daniel
is a junior at Cherry Hill
High School."
Daniel Lasser, MD '74,

eedham, MA, Family
Practice. "My current
position is chair of
Department of Family
Medicine and Commu-

Williamsville, NY, Internal Medicine."! have
been happily married for
29 years (same person).
Hobbies are travel,
hiking, tennis and exercise. I have a daughter
who is applying to
medical school."
says she worked hard to earn
John Rowlingson, MD '74,

he~

education during

a period when state schools awarded scholarships

Earlysville, VA, Anesthesiology. "My years of
practice have taught me
the importance of making pain management a
priority. When the case
is beyond your skillsget help. Remember, we
can't help patients who
won't help themselves."
Jcr3t@virginia.edu

While in medical school, she earned scholarships
and summer jobs covering the costs of books and
room and board. After completing
training, GoHschalk practiced general surgery witli

S limm er

200 0

B u If

a I o Physician

35

�C

L

A

N

0

T

E

he first Minority Alumni Reunion of the University at Buffalo School of
Medicine and Biomedical Sciences was held April 7-9, 2000, at the
University Inn and Conference Center in Amherst, NY. "Coming Together
for the New Millennium" was the theme for the event, which included
social gatherings and an educational program that focused on advances
in the prevention and treatment of common health problems encountered
in minority communities. The keynote address for the reunion was
delivered by Kevin Greenidge, MD '77, who spoke on "Health Care Access
without Health Care: A Minority Dilemma."
Greenidge is professor and chair of the
Department of Ophthalmology at the SUNY
Health Science Center at Brooklyn.
The following Classnotes were submit·
ted by several attendees of the reunion:

JOSEPH OE.JAMES,

36

8 u I I a I o Physician

S11mmer

2000

\10

'96

KEV IN GREEN IDGE ,

\10

'77

�William Sperling, MD '66, Honored
William Sperling, MD '66, has been named

that meet monthly, bringing together pulmo-

the "Dale Daniel, MD, Memorial Partner of

nary physicians and thoracic surgeons from

the Year" by the Southern California

Kaiser Permanente, Balboa Naval Hospital

Permanente Medical Group (SCPMG), a

and UCSD to learn from one another and to

partnership of SOO physicians who care for

improve the care of patients.
County Pulmonary Society and has worked

health maintenance organization. Sperling
joined SCPMG in 1974, when Kaiser

with the San Diego County Lung Association

Permanente was only seven years old in

to help establish a Better Breathing Club for

San Diego. He is credited with establishing

William Sperling, MD '66

an ongoing relationship between SCPMG's

chronic pulmonary disease patients. He has
also chaired the Tobacco Free 2000 Commit-

Internal Medicine Department and the

tee for the San Diego County Medical Society and helped to

residency program at the University of California at

eliminate smoking in the local sports stadium and airport

San Diego (UCSD).

before state law required it.

Sperling is a clinical professor of medicine at UCSD

patients, understand their fears, reassure them and give

addition to teaching at the university, he has actively

them the best care possible," says Maurice Alfaro, a

promoted pulmonary medicine educational programs

colleague of Sperling's at SCPMG.

Wynnewood, PA,
Neurology. "I am very
involved in a professional organization in the
area of headache, and I

Inc. I am spending
my summers in
Zimbabwe, Africa.
BonniDutcher, PhD'7B.

Amherst, NY, Orthope-

Hoffman Estates, IL.
"I am working as a medical science liaison for
Genentech in Chicago.
I set up the clinical trials
with antibodies for cancer

dies. "I am current chair
of Credentials for Kaleida

treatment. l would love to
hear from old friends. "

Health, president of
orthtown Orthopedics,

Bonnllll@yahoo.com

and medical director of
the Millard Fillmore Ambulatory Surgery Center. "

Bennett Yogelman. MD '78.

lecture extensively."
Eschul6641 @home.com
Paul Wierzbieniec, MD '74,

Center for Women's
Health and Women's
Health Research, as well
as the named recipient
of the jean Manchester
Biddick Professor of
Women's Health Research. Their son, Paul,
will start as a freshman
at the University of Wisconsin this fall, and their
daughter, Lindsey, will
begin high school. Molly
and Bennett have fond
memories of medical

4:D

trator of Brandeis
University's business/
management graduate
program from which I
graduated in 1995."
Magjersam@aol.com
Philip Anson, MD '79,

Scarborough, ME,
Orthopedic Surgery.
"After 14 years in a large
subspecialty orthopedic
practice, I took a twomonth summer sabbatical (as a Teaching Fellow
ottingham, England)
111

and Molly Carnes, MD '78.

school, where they met
and are very grateful to

continue to thrive in

Leonard Katz, who

Madison, WI. Both

steered them to UW for

are professors in the
Department of Medicine

their residencies.

Phoenix, AZ. "I am
retired from medicine
and am now a rancher
in Arizona, working for

at the University of
Wisconsin. Bennett is
the associate chair for

Robin Adair. MD '79,

the Bitter Creek Land
and Cattle Company,

education and Molly is

practice for the time

(referee) for both men's

director of the UW

being to be an adminis-

and women's lacrosse.

Richard Zeschke, MD '76.

eedham, MA, Pediatrics. "I've left clinical

hotmail.com

Snyder, NY, Internal
Medicine. "I am currently professor of
medicine and associate
chief of the Division of
Cardiology at UB."
Canty@buffalo.edu
Allen Carl, MD '79,

"Lastly, he's never been too busy to listen to his

and has been active in the pulmonary service there. In

Elliott Schulman, MD '74,

and spine) through
AO-ASIF." Psalax@

John Canty Jr., MD '79,

Sperling is past president of the San Diego

patients in Kaiser Health Plan, a nonprofit

I am also an oral examiner for the American
Board of Orthopedic
Surgery and a lecturer/
instructor (in trauma

in I996 and opened a
solo private practice on
my return. I am team

Slingerlands, Y. "I am
professor of orthopedic
surgery at Albany Medical College. My research
involves spinal cord injury and scoliosis. In
1997 I had a traveling
fellowship with the Scoliosis Research Society."
Alscar@nyca p. rr .com
Terence Chorba. MD '79,

Atlanta, GA, Internal
Medicine. "Buffalo is a
great place to go to
medical school and you
were great classmates to
be with." Tlc2@cdc.gov
Peter Condro, MD '79,

Richmond, VA, Nephrology. "Since 1985 I
have lived in Richmond,
Virginia, practicing with
Richmond Nephrology." E-mail address is:

physician for the U.S.
Soccer Federation, on the

los4441154@::ompuserv.com

board of directors of the

Margaret Garrisi, MD '79,

Maine Lacrosse Foun-

Scarsdale,

dation and an official

ductive Endocrinology

S

11 m 111 e r

2 0 0 0

Y, Repro-

CONTINUED ON PACE 38

Bu ffa l o Ph ysi c ian

37

�CLASS

I

CONTINUED FROM PAGE 37

and Infertility. Mjgraf@
mail.med.cornell.edu

98

Subhabrata Chakraborti,
PhD '84, Tuscaloosa, AL,

"!am working at the
University of Alabama in
the Department of

NOTES

Management Science
and Statististics and am
a professor of statistics.
Published over 30
research articles and
am associate editor of
two statistics journals."
Michael Mercado, MD '84,

Windermere, FL, Family
Medicine. "I've com-

pleted 18 marathons since
I graduated in 1984. I'm
medical director at West
Orange Family Medical
Care (group practice) and
Health Central Park
(nursing home); and
in-structor in Tang
Soo Do Karate at the
Traditional Martial
Arts Center."

A reception for alumni of the University at Buffalo
School of Medicine and Biomedical Sciences will
be held in conjunction with the Association of
American Medical College's annual -.tlng
October 27-November 2, 2000, in Chlcaco.
Chlcaco MarrioH

Kimberly Norris. MD '84,

Middleville, Ml, Ophthalmology, and husband, Mike Nosanov, MD
'84, Otolaryngology/

Head and Neck
Surgery. "We practice
together in our own
practice, eye and E. .T.
specialists, in Hastings,
Michigan. l [Kimberly]
am actively involved in
childhood vision
screening research and
program development."
Mnosanov@voyager.net
William Reichman, MD '84,

Princeton, N), Psychiatry.
"I am director of the
Division of Geriatric
Psychiatry at the Robert
Wood Johnson Medical
School and vice chair of
the Deptartment of Psychiatry. I am also COO of
our university's Behavioral Health System."
Reich man@u md nj.ed u
Kevin Rosteing, MD '84,

Green Bay, WI, Internal
Medicine. "We live in
Green Bay, a 'cool' beautiful place on the Great
Lakes. We own a boat
and spend some wonderful time on the water
with our children."
Kevinr@gbonline.com

38

Buffalo P bysician

S 11111111 C r

2 000

Look for more information at the conference, or
contact Mary Glenn at I 877) 826-3246;
e-mail glenn@acsu.buffalo.cdu.

Randall Solomon, MD '84,
and Susan Abbott, MD '84,

Setauket, NY, Psychiatry.
Randall writes, "My wife,
Susan, and I are both in
private practice of psychiatry. Susan is medical
director of]. T Mathe
Hospital's adolescent inpatient psychiatric unit."
Rsdomon3@bigfoot.com
Michelle Stram, MD '84,

Chalfont, PA, Internal
Medicine. "I've been in
a very successful, busy
cardiology group practice. I am the managing
partner of our office that
employs a staff of 25.
Michael Kaplan (internal
medicine and endocrinology resident and fellow at UB) and I have
two wonderful children
David, 6, and Sara, 4.
Mstram@worldnet.att.net
John Oyster, MD '84,

Lewiston, NY, Family
Medicine. "I am assistant

director of Niagara Falls
Memorial Medical
Center Family Practice
Residency and a member
of the medical school's
Admissions Committee."
David Crandell, MD '89,

Needham, MA, Physical
Medicine and Rehabilitation. " I am team
physician for the Ballet
Theatre of Boston. Team
physician, U.S. Disabled
Sports Team, Athletics
World Championships,
1994, 1998."
Carol DeCosta, MD '89,

Brooklyn, NY, Physical
Medicine and Rehabili tation. "I worked as a
physician for the 1996
Olympic Games in Atlanta. Recently I started
a private practice in rehabilitation and sports
medicine in Brooklyn
Heights, New York.
Cdale2810@aol.com

�Anna Hart, MD '89, Ports-

mouth, VA, Otolaryngology/Head and Neck
Surgery. "I was a U.S.
aval Flight Surgeon for
more than five years,
stationed in Florida, then
Washington State. I resumed my residency in
otolaryngology/head and
neck surgery in 1995 and
will start as chief this
summer. I have presented papers at several
meetings, including the
Academy of Otolaryngology/Head and eck
Surgery and have also

wife, Stacey, and l have
an 18-month-old son,
Ian, and are living in
Westchester County,
New York. Silberj@
rockvax. rockefeller.ed u
Stuart Varon, MD '89,

Baltimore, MD, Child
Psychiatry. "I am
medical director of
child psychiatry at Sinai
Hospital of Baltimore
and an instructor at
johns Hopkins University School of Medicine."
Svaron@sinai-balt.com

In Memoriam
Thomas A. March, MD

psychology at the VA Cen-

South Buffalo for about

'31.

tral Office in Washington,

50 years and was on the

age 96. March

D. C., and as the director

staff of Mercy Hospital

was born in New Castle,

of the VA Hospital at

for 42 years. From 1957

PA. In 1946, after earn-

American Lake, WA,

to 1997, he served as

ing his medical degree

where he retired in 1973.

associate medical direc-

from UB, he completed

In May of that year, in

tor and later medical

postgraduate training

honor of his contributions

director fo the Buffalo

neurology and psychiatry

to psychiatry, March was

Chapter of the Blood

at Columbia Unaversity.

elected a Ufe Fellow by

Collection Program of

He entered the U.S. Army

the American Psychiatric

the American Red Cross.

Air Force Medical Corps

Association. He is sur-

He was also a clinical

in 1942 and became a

vived by his wife, Rorie;

instructor at UB for more

flight and group surgeon

daughter, Peggy Ander·

than 40 years. In addition

for the 8th Air Force

son; son Thomas D.

to his wife, Eleanor, he is

published three papers.
I am on the editorial

1990s

Squadron based in En-

March; and stepsons

survived by five daugh-

review panel for our
academy's (Oto/H S)
journal, which keeps me
busy as well." Email is:
Toddandkristina@msn.com

Lyn M. Oyster, PhD '90,

gland. He achieved the

Richard and Greg Nace.

ters and three sons.

received University at
Buffalo's Distinguished
Alumni Award at the
Alumni
Association's

rank of Lt. Colonel and
Elton Rock, MD '59,

1947, March joined the

Edward L. Valentine, MD
'45,
ent died Febru-

Veterans Administration

ary 25, 2000, at age 80.

Alzheimer's Disease.

Department of Medicme

A World War II veteran,

Rock started the Depart-

in Pittsburgh, PA. During

Valentine served in

ment of Gastroenterology

his VA career, he served

Batavia, New Orleans and

at Sisters Hospital in

as the director of the VA

Asheville/Black Mountain,

1970 and headed It until

Hospital at Bedford, MA,

NC, as a Navy medical

illness forced h

Oyster is a founder and

as the deputy director of

officer. He had private

retire in 199

president of GenCyte,
LLC, a microbiology
company that patents
genetic markers for
breast cancer. The company will leverage its
skill base in molecular
biology, microbiology
and cell culture to
perform biologic laboratory services. It also
plans to develop cellculture products for sale

psychiatry, neurology and

practices in Elma and

Andrea Messina, MD '89,

Wayzata, M , Obstetrics/Gynecology. "Hugh
eeson and I work in the
same large multispecialty
group with over 350
physicians in Minneapolis. I never thought a
neuroradiologist and OB/
Gyn would work for the
same group; it's supposedly the shape of things
to come."
Jeffrey Silberzweig, MD
'89, Elmsford, NY,

Internal Medicine.
"I am currently the
medical director of the
Rogosin Institute's
Queens Dialysis Center

annual
awards
dinner on
April?,
2000.

Cornell University
Medical College. My

American Academy of
Orthopaedic Surgeons
during ceremonies at the
academy's 67th annual
meeting in Orlando, FL,
on March 15, 2000.

after a long battle with

CD

Maxillofacial radiology

child. We are moving

at Virginia Commonwealth University School

into our first home, in
Rockville, Maryland. I

of Dentistry, MCV
campus, effective

am presently an assistant
clinical professor at
George Washington

August l, 2000.

Elissa (Jaffe) Bookner, MD
'91, see Scott Bookner,

Richard Safeer, MD '93,

writes: "After finishing

University and the associate program director
of the Family Practice

MD '89.

my residency in Ba ltimore, I married a won-

Residency Program
there. I am really enjoying teaching and, in

to niche markets.
Laurie Carter, DDS '83, PhD
Glen M. Ginsburg, MD '90,

derful woman. A year

'93, has been appointed

of Omaha, NE, was in-

and a half later, we are

associate professor and

ducted as a fellow of the

pregnant with our first

director of oral and

and an assistant professor of medicine at

served in the Air Force
Reserves untii19S3. In

5

11 111 111

e r 2 0 00

I

CONTINUED ON PAGE 40

Bullalo Phys i c i an

39

�CLASSNOTES

particular, I have had a
chance to do some
writing and lecturing on
the topic of cholesterol
management."

New Alumni Association

Sarah Finnegan, MD/PhD
'94, has received a

Electe

Alumni Association. Duffner is a UB
professor of neurology and pediatrics and a physician in the Depart=-

John J. Bodkin, II, MD, was elected presi-

ment of Neurology at Children's

dent of the Medical Alumni Association on

Hospital of Buffalo.

April 29, 2000, at Spring Clinical Day.

$10,300 grant from
Fight for Sight, the
research division of
Prevent Blindness
America, to conduct
a study titled "Human
Photoreceptors in
Culture: Growth
Factor Requirements
and Potential
Gene Therapies." &lt;I;)

Bodkin, a 1976 graduate of UB, is

Colleen Mattimore, MD, class of 1991, is

a clinical associate professor of

the new treasurer for the association.

family medicine and president

Mattimore, a UB clinical instructor of

of the Highgate Medical Group in

pediatrics, is on staff at

Williamsville, NY.

Kaleida Health's Children's
Hospital and Mercy Hospital

Patricia K. Duffner, MD, class of 1972,

of Buffalo.

becomes vice president of the Medical

A plan for living.
Hospice really is a plan for living.
And the sooner you call, the sooner
we can help you put that plan into
action - with emotional support,
pain management, in-home care anythjng you need to keep
enjoying life. Ca/1686-8077.

TilE

CE:-..:TER

FOR

H"')SPICE&amp;

PALLIATIVE CARE
www. hospiceb1!{folo. com

40

luffalo

Physician

S11mmer

2000

��- Based on FIMsM Data

t t

They were drJl sergeants-

and cheerleaders~'
- Frank Stelarski, stroke rehab patient, Harris Hill H.C.F

Why do our patients have better rehab resuh:s compared to the national average? Maybe rt's our staff.
''They knew exactly how far to push me,' ' says Frank Stelarski.''But they also encouraged me every little
step of the way. When you've been through what I have, that really means a
lot.'' To leam more about the nationally recognized McGuire Rehabilrt:ation

THE

UJ1CGUIRE

~HABILITATll91'{

CENTE~

Centers, call 1-888-POSTACUTE or visrt: www.mcguire-group.com.

1\ccognizcd ror excellence in guality care.
AUTUMN
BP 000 1 0 1

VIEW

•

GARDEN

GATE

•

HARRIS

"*****"

HILL

•

NORTH

GATE

�</text>
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P~ysicial

ASSOCIATE VICE PRESIDENT FOR
UN I \ ERSITY SERVICES
Dr. C a role S mi t h Petro

Dear Alumni and Friends,

DIRECTOR OF PERIODICALS
Sue Wue t cher

EDITOR
S t eplwnie A. Unger
)I

(,

!

, the fi rst of the new millennium

(depending, of course, o n how o ne defines the start date of a new millennium). We have
just completed another highly successful orientatio n week for inco ming freshmen, which
concluded wi th the now-traditio nal White Coat Ceremo ny. Dr. Robert A. Milch, MD '68,

ART DIRECTOR/DESIGNER
A lan ]. Kegler

AssiSTANT DESIGNER
Lynda Dona t i

directo r of the Center fo r Hospice and Palliati ve Ca re in Buffalo, delivered an inspiring
message to the first-year class and their parents, spo uses and friends. Dr. Do n Pachuta, MD
'66, addressed the second -yea r students, focusing his comments on the humanistic philosophy
that sho uld- must-underpin the physician's approach to learning and to practicing
medicine. Do n is in the process of creating an endowmen t that will suppo rt an a nnual
lectureship on the "humanism" underpinnings of medici ne.
Students also received a copy of the new Code of Professional Conduct,
published in an elegant booklet. Printing expenses for the booklets were
underwritten by a generous unrestricted gift from Dr. and Mrs. Edward
Shanbrom (Ed is an MD '51 alumnus who now resides in California). A
special article on the code and how it was developed by our students last
year will be presented in the winter issue of Buffalo Physician, which will
also feature the complete text of Dr. Milch's talk. All in all, it has been an
excellent start to the new academic year.
This is the time of year fo r new arrivals to the uni versity. Dr. John Yeh joined us ea rlier
in the spring as chair of Gynecology-Obstetrics. Even during this short period of time, the
departm ent has undergone remarkable rejuvenatio n. In addition to four new faculty

PRODUCTIO!'i COORDINATOR
Cynthia Todd-Flick

STATE l.JNI\ ERSITY OF NEW
YORK AT BuFFALO ScHOOL
OF MEDIC INE ~ND
BIOMEDICAL SCIENCES
Dr. / o lm Wrigh t , Dean

EDITORIAL BOARD
D r. B e rt ra m Portin, Chair
Dr. Martin Brech e r
Dr. H a ro ld Brod y
Dr. Linda f . Co rde r
D r. A lan f . D ri nnan
D r. fam es Ka n ski
Dr. Eliz abeth Olms t ed
D r. S t eph e n Spa ulding
Dr. Bradley T . T ru ax
M s./ en n ife r Wiler
Dr. Franklin Zeplowitz

(besides Dr. Yeh}, the teaching programs at both the resident and medical student levels

TEACHING HOSPITALS

have received new life and there is an air of optimism and enthusiasm in the department.

Erie Co unty .\fedica/ Ce nter
Roswell Park Cancer In stitute
Vetera ns Affairs Western
New York Hea lthcare System

Dr. Ken Blumenthal arrived in early August to assume the chair of Biochemistry. We are
confident that he will grea tly strengthen this department, in terms of bo th its program and
its wo rking relationships, and we all look fo rward to wo rking with him as he remolds this
esse ntial basic-science department.
In ea rly July, Dr. Elizabeth Capaldi joined the university as o ur new provost. For us, in
the medical school, this is an extremely impo rtant positio n beca use it represents not o nly
overall academic program leadershi p fo r the university, but also for the School of Medicine
and Bio medical Sciences. This is a particularly critical period for the medical school as we
attempt to remain current in teaching and resea rch yet accomm odate the buffeting fo rces
that are all aro und us in the clinical enviro nment.
One of the majo r tasks of the fall semester will be to fashion a durable affiliatio n

KHHDA HI:A.IIII:

T he Buffalo General Hospital
Th e Ch ildren's Hospital of Buffalo
Millard Fillmore Gates Hospi tal
Milla rd Fillmore S ubu rban
Hospi tal
CATHOliC H fAITif Sr.\TF.\1:

Mercy Hea lth System
S ist ers of Charity Hospi tal
N iagara Fa lls Me m orial
M edical Cen ter

® THE STATE INIYUSIIY Of NEW YllliJIUIFlll

agreement with Kaleida Health System (the merged Buffa lo General, Child ren's, Millard
Fillmo re and DeG raff hospitals) . Central SUNY administratio n and community leadership will be very much involved in the process, which will likely chart the future directio n
of o ur school and its clinical programs. No doubt it will be a fea tu red article in an upcoming
Buffa lo Physician. We will certainly keep you posted.

j OHN

R.

WRI GHT. MD

D ean, Schoo l of M edicin e and Biom edical Scie n ces

Buffalo Physician is published
quarterly by the State Uni1·ersity of
New York at Bujjalo School of
Afedicit~e and Biomedical Scieuces
and the Office of Pu/JiicatioiiS. It is
sent, free of charge, to alumtll,
facultj·, students, resiLICtJts, and
friends. The staff rcscn'es the right
to etfit all ropy aud submissions
arrcpted for publiwtwn.

T~

at Buffalo
-:.:=:s University
Tire State University ofNew York

�VO L UME

35,

p

H

y

c

s

A

Features

2

Internal Medicine's Man
James P. alan's extraordinary
contributions to his field and
UB's Department of Medicine
BY

S .A .

UNGER

PHOTOGRAPHY

12

BY FRANK MILLER

Eschewing Viewing
Obese children learn to replace
television with other activities
BY

S. A.

UNGER

PHOTOGRAPHY BY

MARK DELLAS

UB professor of pediatrics and psychology Leonard H. Epstein, PhD, has
conducted pioneering research on childhood obesity for the past two
decades. On page 12 begins astory about his current work aimed at
teaching obese children to choose active behaviors over sedentary ones.

COVER

16 Annual Faculty
Awards

17 McAloon
receives 2000
Humanism
Award

18 Nielsen elected
AMA's vice
speaker

26 "Lonely for a

20 Auerbach wins
jacob )avits
Award

21 Hypertension
redefined

23 Colon polyps
unaffected by
healthy diet

Sciences Career
Day a success
White Coat
Ceremony

25 Professors
Albini and
Gabrieli
remembered

Calling of My
Own"-Umut
Sarpel, class
of2001, finds
clinical rotations include
an exercise in
introspection

PHOTO

29 Endowments
crucial to
chool's future

30 Listing of
current
endowments

BY

FRANK

MILLER

your UB
classmates and
other alumni

N

��alkins certainly had this far-reaching goal in mind when
he called • ' olan, but what he couldn't haw known at the
time was that he was setting in motion a successful recruitment effort that would bring to the L'niversity at Buffalo a
future chair of its Department of ~1edicine, and a man,
who along with himself, would lead the department for a
combined total of 3-l years. :\ot only would :\olan go on to
work with Calkins to oYersee the growth of UB's Department
of ~lediLine from approximateh- 50 faculty to more than 150,
but he would also pia~· a leading role nationalh· in academic
medicine, eventually serYing as president of the Association of

Professors of ~1edicine and chair of the Board of Regents for the
American College of Physicians.
\\'ith his "official'' retirement from the State of, ' ew York in
July 1999, • 'ohm brought to a dose a career in medicine that
would have to be considered exemplary by any standard. Contributing to his stature is the fact that man\' of his colleagues and
former students feel strongly that he will be remembered not so
much for his long list of accomplishments as for his distinctly
artful style of leadership-a stYle that could perhaps serYe as a
model for any physician-leader today whose goal is to bring
out the best in others under the most difficult of cirwmstanct&gt;s.

�The Early Years
hen Calkins first approached Nolan about returning to UB, the university was still in the throes of adjusting to the enormous
change it had undergone in 1962, when the University of Buffalo-a medium·sized private college founded as a medical
school in 1846-was incorporated into the State University of New York (SUNY) system to form SUNY at Buffalo or,
more simply, the University at Buffalo.
Once the realities of this transition began to take shape, it soon became evident to everyone involved that the state was
not just absorbing the buildings, faculty and staff of the University of Buffalo; it was also absorbing its remarkable history
and ethos dating back 116 years to when the school was founded by such men as Millard Fillmore, James Platt White,
Austin Flint and Frank Hastings Hamilton, all of whom went on to make their mark in the annals of American medicine.

Added to this stir of proud history and state incorporation were the sweeping changes taking place in
academic medicine at the national level. In large part,
these changes were fueled by an unprecedented influx
of dollars from the National Institutes of Health into
the nation's medical schools, with the goal of promoting
the growth and development of academic departments
capable of fostering excellence in research.
If a medical school were to compete nationally with the

lulfalo Hpicin

Autum11

2000

rush to develop sound academic departments that
boasted the best and brightest in clinical and research
faculty, then the best and the brightest it must recruit.
At the time Calkins first contacted him, Nolan had just
completed a clinical fellowship in medicine in the Liver
Study Unit at Yale University's School of Medicine and
was finishing up as chief resident in medicine, all the
while contemplating the likelihood that he would set up
practice in ew Haven, Connecticut. During his internship a few years earlier, he had met
Christa, a student from Sweden who
was studying microbiology at the
university, and the two had married
and begun a family. Returning to
Buffalo was not in the picture.
Calkins himself had come to
Buffalo from Harvard University
in 1960, when he was chosen to
succeed the eminent internist John
Talbott, MD, who had left UB to
accept the editorship of the journal
of the American Medical Association. While at Harvard, Calkins had
become acquainted with Dr. Paul
Beeson, professor and chair of
medicine at Yale, whom he had
talked with on several occasions
about career opportunities. When
Calkins was first offered the job as
head of medicine at Buffalo General Hospital, he turned to Beeson for advice about whether or
not he should accept the position.
"Dr. Beeson had some connection with Buffalo," Calkins recalls.
"I think his wife was from here.
When I asked him what he thought
about my coming here he said,
'Absolutely! It's going to be a great

�The establishment of the division of endocrinology marked the stan of abuilding program
that would continue for the next 17 years as 13 major divisions were gradually formed
within the Oepanment of Medicine.
opportunity and challenge. You get up there and get
things going and then we'll exchange residents. '
"Well, what more terrific confidence could you give
any young man coming into a program by saying on
behalf of one of the major departments in the country
that the chair would exchange residents?" asks Calkins.
CE I B UFFALO, Calkins set to work identifying potential areas of growth and concomitant recruitment needs.
At the time, the Department of Medicine for the university was cochaired by the heads of medicine at Buffalo
General Hospital and Edward ]. Meyer Memorial Hospital (now the Erie County Medical Center). Calkins's
counterpart at E. ]. Meyer Hospital was the legendary
clinician David K. Miller, MD, the first full-time faculty
member in medicine at UB, who had been head of medicine at the hospital since 1940. For many years, the two
hospital-based departments operated largely independently; however, with the arrival of Calkins and the incorporation of UB into the SUNY system, the two heads of
medicine began to acknowledge the necessity of working
more closely to develop a university-wide department.
In 1968, Miller volunteered to step down as cochair of
the department. Following a national search, Calkins was
chosen to lead the department, with the aim of developing
it as a unified entity.
From the time of his arrival at UB eight years earlier,
Calkins had aggressively taken the lead in recruiting new
faculty for his group at Buffalo General Hospital, which
had a good base of clinically oriented faculty but a very
limited number of research-oriented faculty, as was also
the case at the E. ]. Meyer Hospital. "We were in a new
era of medicine, where the emphasis was on integrating
clinical and basic-science approaches," recalls Calkins.
"We identified several areas where we thought if we put
all our strength and energy into building in-depth, we
would be able to develop programs that could be
nationally competitive and attract major funding from
the NIH, as well as set the standard for quality of care
and for the teaching of students and house staff. "
At the time, Calkins estimates that there were only
about three or four facult y members in the Department
of Medicine who were involved in focused research
efforts. The first area that was identified as having a

strong basic-science foundation upon which to build
was endocrinology. Because the researchers in this
group-most notably Dr. John Plager-were located at
Roswell Park Cancer Institute, Calkins led an effort to
bring them into the Department of Medicine at UB and
give them faculty titles. He then recruited Dr. Keith
Vance to head the new division. The establishment ofthe
division of endocrinology marked the start of a building

Alltllmn

2000

luffal1

Physician

5

�-

--

-

--------------------------------------------~~=---~~-

program that would continue for the next 17 years as 13
major divisions were gradually formed within the
Department of Medicine.

medical school's teaching programs and faculty are disbursed among Buffalo's major community hospitals. For
the Department of Medicine, this meant faculty would
continue to be located in three hospitals: Buffalo General
Hospital, Erie County Medical Center and the Department of Veteran's Affairs Medical Center.
"On balance, I think that a university hospital is a
tremendous advantage," says Nolan. "And I have always
pushed for one, as did Evan Calkins before me. I never
made it a secret that I thought that was the way we ought
to go. But, early on--in the early 1970s--it was clear it
wasn't going to occur, so then one had to accept it and
make the best of it, and I think we did."

Time to Bring the Talent Home
EVERAL YEARS INTO THIS EFFORT, Calkins says he and
Vance "got pretty lonely in coordinating the broad teaching responsibilities designed to integrate the basic
sciences with clinical medicine." Thinking it time to bring
someone on board who could help them with this work,
Calkins again turned for advice to Yale's Paul Beeson,
who recommended olan, his former chief resident.
In the years ahead, olan and Calkins would fondlyand humorously--remember the recruitment effort that
ensued. "We didn 't have much money back then and nobody would give us departmental funds for this type of
thing, so when Jim came to Buffalo, we took him to a
restaurant in the Southtowns where, for something like
$3. 75, you stood in line and got your own food. Years later,
when Jim and I were actively recruiting somebody
and were trying to pull out all the stops, we took the person
out for a nice dinner. Later, in an attempt to describe the
dinner to someone, Jim joked, 'You know, it was the kind
where you get waited on,"' Calkins recalls with a laugh.
Smorgasbord dinner aside, Nolan found himself
swayed by Calkins and soon he and his family were on
their way to Buffalo, where he had accepted a dual position
as associate professor of medicine at UB and clinical
associate in medicine at Buffalo General Hospital. "Evan
Calkins is a very dynamic recruiter," says Nolan, adding
that the early 1960s
were "very heady
times for the university. SUNY at Buffalo
was to be the flagship campus--the
'Berkeley of
ew
York State'--and it
was a timeoftremendous growth."
olan further explains that one of the
great attractions that
drew him back to
Buffalo was the plan
to build a new university/county hospital on the South Campus, at Bailey
and Winspear, but recounts how, over the years, that
idea--as well as a whole series of plans to relocate the
medical school--was scuttled. It wasn't until the early
1970s that administrators finally made the decision not
to build a university hospital and instead put into place
the still extant affiliated-hospital model whereby the

6

lulfala Physician

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11t11 11111

2000

A Cool Head on the Hot Seat
"

AKI G TH E BEST OF IT," according to Calkins,

involved putting Nolan to work using a special
talent he was discovered to have soon after his
arrival at UB.
"We didn't have the power structure to
work with that's in place today; we had to be
on the various hospital committees and win
by persuasion, by political savvy, in a sense," Calkins
explains. And, as luck would have it, he and others soon
recognized that olan had a remarkable talent for sitting
on these committees and effectively lobbying for the
needs of the Department of Medicine.
"Jim is easily the best committee man that I have ever,
ever seen," Calkins says. "We knew that if we put him on a
committee, we could be certain that it would come out
exactly the way the Department of Medicine wanted. Jim
would sit down with all these senior people and he would
represent our position by using his personal interdynamics, by taking a modest, friendly approach, never
overemphasizing anything, not getting purple in the face
and not pounding the table. This is just who he is and
everybody liked and respected him very much and would,
in large part, agree with the steps he proposed."
As time went on, according to Calkins, olan grew
increasingly practiced with committee work, and his
skills became invaluable to the department and to the
school of medicine. "He of course got better at it because
we were always giving him the hot seat," Calkins recalls
with a chuckle. "We didn' t waste him on the obvious
[committees]. We put him on the ones where the whole
future of the department would hinge. He was always
much better at this work than I was because I would
come in and be much more confrontational, more
demanding, more un yielding.
"This talent of Jim 's was a lead feature for him
throughout his career," he adds, "and I know the dean
on several occasions appointed him to chair very tricky
committees involving subtle areas of great importance

�" Making the best of it," according to Calkins, involved putting Nolan to work using aspecial talent
he was discovered to have soon after his arrival at UB.

to the school. Also, when he became involved with the
American College of Physicians and the Association of
Professors of Medicine he was able to do the same kind
of work wonderfully well."

Building on Buswell Fellowships
Y THE LATE 1960s, the Department of Medicine faculty
at Buffalo General Hospital had grown out of proportion
to the needs or scope of care at the facility. "We were
really bulging at the seams. We must have had at least
25 well-established young scientific doctors who had
achieved national recognition and were getting major
grants," recalls Calkins.
At the same time, the county hospital was struggling
financially and its faculty in medicine remained primarily
clinically focused. Given this situation and the resignation
of D. K. Miller as cochair of the department, the time was
right, according to Calkins, to begin to bring the county's

faculty into the new model for the department. To
accomplish this complex transition, Calkins decided it
was necessary to move a third of the department's fulltime faculty over to the county hospital. Also at this time,
the decision was made to move the department's administrative offices to the hospital, where they remain today.
A key factor that made it possible for the Department
of Medicine to continue to grow over the next decade was
the availability of Buswell Fellowships through the school
of medicine.
"One of the main reasons why the timing was right for
what we were trying to do is that we had about 15 of these
faculty fellowships at the assistant professor level, which
were given on the condition that the faculty coming in
spend 90 percent of their time on research during their
first two years," explains Calkins. "So we figured that, in
time, the financial support would begin to grow as these
scientists became more clinically oriented, got more

Autumn

2000

11 flail

n

y sic i a1

1

�patients coming in, developed as teachers and won recognition
for their research activities."
The plan, therefore, was to make full use of the Buswell
Fellowships to recruit future division heads who would "get
their feet on the ground while Jim and I were carrying out the
core work of the department," Calkins recalls.
In addition to olan, Calkins was working closely with
Dr. Thomas Tomasi, who had joined the department in the early
1960s as head of immunology and was instrumental in recruiting key faculty to the department. "Tom Tomasi was a major
colleague of ours for eight years. He played a very, very important
role in the department during those early years because he
helped us identify the key frontiers of scientific medicine and the
people we should try to bring into the department," says Calkins.
In all, the effort of these and other leaders in the department
met with extraordinary success, and today both Calkins and
olan proudly point out that of the core group of faculty
brought into the department during their combined tenure,
some 25 have gone on to chair departments or hold similar
appointments elsewhere around the world (see list on page 10).
Another area in which great strides were made involved
the recruitment of talented residents, according to Calkins.

"Dr. olan and Vance and I made a tremendous effort to recruit
top-notch house staff in these early years because we recognized
that some of the most effective teaching of medical students is
carried out by these individuals, who also serve as role models
for the students," he explains
"So at a time when internal medicine occupied a particularly
strong place in the eyes of medical students and house staff, we
succeeded in attracting an exceptionally strong group of graduates from UB, as well as from such schools as Harvard, New
York University, Temple, johns Hopkins and the University of
orth Carolina," he adds.

The Heart and Science of Medicine

1969, OLA WAS appointed professor of medicine in the
department, and in addition to his growing administrative
and teaching duties, he also continued to lead an active
research program in liver disease and the effects of endotoxins. In the 1970s, he and his group made key discoveries that
led to a better understanding of the role these toxins play
in liver disease when the liver is affected by alcoholism and
hepatitis. They also determined that antibiotics can worsen
some liver diseases by increasing endotoxins.
olan had also by this time established a stellar
reputation as a teacher and clinician. "Jim is one of
the most informed internists I know," say Robert
Internal Medicine House Staff, 1976. A complete listing of those pictured here is not available;
Klocke,
MD '62, current chair of the Department
however, the following individuals have been identified: Susan Arbuck, Thomas Avery, Raymond W.
Bergenstock Jr., James Cirbus, Richard Curran, Richard Dolinar, Helen Findlay, Geraldine Kelley,
of Medicine, who came to UB in 1970 when the
Steve Lanse, Alan Leibowitz, Trudy Masters, Nancy Nielsen, James P. Nolan, MaHhew J. O'Brien Jr.,
department was just beginning to be more inRichard Rosenfield, Marilyn Telon, Henri T. Woodman, AntoineHe Wozniak.
volved with the county hospital and who, in
19 78, was named head of the Pulmonary
Division there. "He knows a lot about everything,
not just his specialty of liver disease, and he is an
excellent teacher.
"I think the students who really appreciated
him the most over the years were the residents,
who benefited from his impromptu teaching at
the bedside," Klocke adds. "He has such vast
knowledge and yet organizes material very well
when teaching. Also, because he doesn 't just
focus on one thing and then another, he is able
to see the big picture."
"What's been important to me about teaching,
in addition to the content itself," says olan, "is
that, hopefully, you can mold individuals into
compassionate physicians. And I have always tried
to stress this when dealing with patients and with
students-the idea of professionalism, of compassion and empathy."
olan's gift for teaching both the "heart and
science" of medicine resulted in his being twice
chosen by residents to receive UB's coveted White
Coat Award, which honors "excellence in teaching

8

Buffalo Hpician

A utum tz

2 0 00

�and outstanding contributions to the education of house staff."
Today, olan says he considers these awards to be among his
most prized honors at UB.

Creative Funding and Support for Faculty
KEEP! G WITH HIS GROW! G stature as a teacher, researcher
and administrator, Nolan was named vice chair of the Department of Medicine in 1973 and acting chair in 1978, when
Calkins retired from that role. A year later, he was appointed
chair of the department, a position he held until1995.
"The first few years as chair of a big department like that are
tough because you have to prove yourself, but then, over time,
you gain confidence," says olan. "But the major thing I had
going for me from the start was that I had good division heads
and clinical directors, so after a while I was in a position to
delegate and to do other things as well. Really, I was blessed with
very, very good associates who took on major roles in both the
educational and the research aspects of the department."
While the department's faculty were exceptional, olan
admits that their being housed in three hospitals did pose an
ever-present challenge for him. "With the resources of a full-time
faculty spread throughout three community hospitals, it's difficult to achieve a critical mass in any one location," he says. "This
is especially true for the smaller divisions. It was also difficult to
obtain the laboratory space that was needed for the department."

An even larger dilemma for Nolan throughout his tenure as
chair, however, was the chronic shortage of funds brought about
by severe cutbacks from the state and Medicare, in combination
with new fiscal austerities imposed by managed care.
"Throughout the 1980s and '90s, the hospitals in Buffalo were
very badly squeezed-as were hospitals everywhere," explains
Nolan, and this directly impacted the medical school and
Buffalo's entire health-care community in ways that hadn't
been felt before, he contends.
"There were times in the '60s and '70s and even into the early
'80s, when the hospitals would get into some financial trouble
and the university would just pick up their lines, and there were
times when the university would get into trouble and the hospitals would step in. Nobody's helping out now; everybody's
having to look out for themselves, and over the past 10 years it's
become a tremendously competitive environment.
"Even though we are a state school, the percentage of our
budget that comes from the state for salary purposes is only
about 15 percent; that's not a lot," he continues." owadays, over
50 percent of the compensation for the full-time faculty, even
in a big department like medicine, comes from practice dollars,
and those dollars are increasingly hard to come by."
olan explains that these and other funding pressures have in
turn "greatly impeded our ability to teach medical students in an
ambulatory setting because the practicing physicians, who have
always been supportive of teaching students in their offices, are
having increasing difficulty doing this because they are under
such tremendous pressure to process patients at a rapid rate."
Given the pervasive funding shortages olan had to confront
as chair, Klocke says it's a tribute to him that the department
continued to grow-albeit not at the earlier pace-and that the
faculty, for the most part, functioned as a cooperative and
cohesive group.
"Jim was very creative when it came to finding funding," he
says with a smile. "He would go around and sell people on an
idea, and then get a piece of funding from here and a piece from
there and put together all the little pieces. I was able to recruit an
excellent person from Yale-Jamson Lwebuga-Mukasa, who's at
Buffalo General now-because Jim helped convince the hospital
and the dean to make an investment. He was always very
supportive in this way.
"Too, Jim has a knack for making people feel wanted, and he
is very good at acknowledging people's contributions in a quiet
way," Klocke explains.
"Actually, everything he does is done in such a low-key,
gentlemanly way," he adds. "I have heard people who did not
agree with him, but I've never heard anybody say he wasn't a
nice person. Even when he had to make tough decisions that
somebody didn't like, you knew it was never personal.
"So even though there were huge cutbacks from the state and
lots of financial and administrative problems when he was chair,
he kept everybody going, and our department actually continued to

Aut um 11

2000

II

f f If I H JS i

C iII

9

�grow. And thereally nice thing for
me is that I inherited from him a
happy and extremely cooperative department."
When asked
what he consider
to be highlights of
his tenure as chair,
olan says he is in
many ways most
proud of the research efforts of
the department. "At one time, we had more IH dollars than any
other department in the four [SUNY] schools," he says, "and that
was a source of great pride for our department-that we were able
to attract people of that stature. And I think, as such, we developed
a very good national reputation for the department as a place for
young faculty to work. And during my time, as well as Evan's, we
exported some very good people to other very good schools."
In addition to this, olan says that he is also proud of the work
he did in support of affirmative action during the 17 years he was

Former Faculty Members

chair. "We were all involved in affirmative action at that time in
the sense that we made a real effort to attract medical students
from the minority population who were superb," he explains.
"Buffalo did extremely well in terms of percentages in this
--area~he add,-'' and I'm proud of that."

A Mentor and a Model
N THE EARLY 1990s NOLA became an increasingly visible
leader in academic medicine in his role as president of the
Association of Professors of Medicine, a group comprising
chairs of medicine across the nation, and as chair of the Board
of Regents for the American College of Physicians. Both
organizations provided a forum for him to address a central
concern he had at that time: the trend toward specialization
in internal medicine; in particular, the fact that 70 percent of all
medical-school graduates were going into the specialties and only
30 percent into primary care areas. Many people feel that the
energy and attention Nolan dedicated to this problem while a
leader with both these organizations contributed significantly to
the reversal of this trend by the close of the decade.
"If you look at his writings from the '90s, you'll see he was
writing very frequently in the Annals of Internal Medicine and
other journals, talking about the value of the internist," says
Klocke. "And as president of the Association of Professors of

director, Fogarty

Robert A. Murgita, chair and pro·

International Center and associate

fessor, Department of Microbioi·

Gerald Keusch,

T HE FOLLOW! G IS A LIST of former fac u lty members in
Un iversity at Buffalo's Department of Medicine who hold or
have held positions of chair (o r comparable positions).

James C. Allen, chair, Department

David R. Dantzker, president, Long

of Medicine, University of South

Island Jewish Medical Center, New

Carolina; subsequently, vice presi·

Hyde Park, New York

director, International Research,

ogy and Immunology, McGill Uni·

National Institutes of Health,

versity, Montreal, Quebec

Bethesda, Maryland

James P. Nolan, chair, Department
Frances J. Klocke,

director,

of Medicine, State University of New

Feinberg Cardiovascular Research

York at Buffalo, Buffalo, New York

Institute, Northwestern University
Medical School, Chicago, Illinois

dentfor medical affairs, Roper Hos·

Medicine, Albany Medical College,

Michael A. Apicella, chair, Depart·

Albany, New York

ment of Microbiology, University of
Iowa College of Medicine, Iowa

Robin DeAndrade,

ment of Physical Medicine and Re·

of Medicine, Atlanta, Georgia

president, McMaster University

10

professor of medicine, Tufts-New

ment of Medicine, State University

England Medical Center, Boston,

of New York at Buffalo, Buffalo,

Massachusetts

Thomas Provost,

ment of Medicine, University of

HamiHon, Ontario

Illinois, Chicago, Illinois

A!II!IIIITI

2000

chair, Depart·

Albert F. LoBuglio, medical direc·

ment of Dermatology, Johns Hopkins

tor and professor, Comprehensive

University, BaHimore, Maryland

Cancer Unit, University of Alabama,
Birmingham, Alabama

Lawrence Frohman, chair, Depart·

fessor, McMaster University,

luffllo Hysicin

chair, Depart·

chair, Depart·

habilitation, Emory University School

Medical Center; currently, pro·

Robert A. Klocke,

New York

City, Iowa

John Bienenstock, dean and vice

director, Digestive

Disease Research Center and

Paul J. Davis, chair, Department of

pital, Charleston, South Carolina

Andrew Plaut,

�Medicine, which is a small but very influential group, he certainly
played a major role in shaping the approach that chairs of medicine in this country took in terms of teaching primary care and
what roles the departments of medicine were to play in this."
Through the American College of Physicians, olan also participated in the national debate taking place in the early 1990s over
President Clinton's proposed health-care plan. "This was a very
exciting time on several points," he says. "One was the issue of
needing to train more general internists, and the other was the
whole question of universal health care. And this [latter] issue is
one the college has always been in favor of; we believe everyone
should be insured, so while I was chair of the Board [of Regents]
we had meetings at the White House. I think many of us,
myself included, were very disappointed that we didn't get
something out of that," he says.
Klocke feels that Nolan's national visibility as a leader in academic medicine has been invaluable to UB faculty, not only because it has "opened a lot of doors," but because it has provided a
model of public service for others to emulate. "When I was offered
the position of editor of the American journal of Respiratory and
Critical Care Medicine in 1989, Jim was entirely supportive of my
taking on this responsibility, even though it took up an enormous
amount of my time for five years," says Klocke. "He felt it was
important for my career, as well as for the university, and he was

happy for my success, just as he always was for others."
Since his retirement from the state in July 1999, Nolan has
continued to write and see patients on a consulting basis. At
Klocke's request, he is also helping with recruitment for the
department and has agreed to continue serving as acting head
of the Division of General Medicine until that position-which
was vacated two years ago-is filled.
Klocke says Nolan has been extremely supportive of him since
he became chair of the department but, at the same time, has been
careful not to exert his influence on the day-to-day operations of
the department. "Jim has been very helpful to me since I became
chair, yet he purposely moved his office to another floor so he
wouldn't be around, wouldn't be in a position to second-guess
me," says Klocke.
"However, when I need advice, he's there for me. And on a
couple of occasions, he's just stopped by and said to me, 'I know
people don't come in to tell you that you're doing a good job,
but I just wanted to let you know that things have gone well.'
"That's been very heart
Special thanks to University
warming," says Klocke.
Archives, Dr. Evan Calkins
But coming from the "best
and Dr. \Villiam A. Fleming
committee man ever"-and
for their assistance in locating
a gentleman-certainly not
photographs for this article.
very surprising.
4D

chair,

David Schmidt, chair, Department

Roswell Park Cancer Institute,

This list was compiled by

Department of Medicine,

of Family Medicine, University of

Buffalo, New York, and chair, De·

drawi11g on the collective

University of California,

Connecticut

partment of Molecular Medicine,

mem ories of current and

San Diego. (Dr. Ranney was

Farmington, Connecticut

State University of New York at

former members of UB's

Buffalo, Buffalo, New York.

Department of Medici11e, mzd

Helen M. Ranney,

Health

Center,

the first woman to chair a
department of medicine in the

John B. Stobo, chair,

country.!

of Medicine, Johns Hopkins Uni·

Philip H. N. Wood,

chair, Depart-

to ensure its accuracy and

versity. Currently, president of Uni·

ment of Epidemiology, University

completerzess. Corrections or

Morris Reichlin, vice president for

versity of Texas Medical Branch,

of Manchester, England

commerzts are welcome and

research at Oklahoma Research

Galveston, Texas.

every attempt has bee11 made

Department

can be sent

John R. Wright, chair, Department

Foundation, and George

via

e-mail to

bp-notes@buffalo.edu; or by

Lynn Cross Distinguish·

Thomas Tomasi, chair, Department

of Pathology, State University of

writing to editor, Buffa lo

ed Professor, University

of Immunology, Mayo Clinic/Medi·

New York at Buffalo. Currently,

Phys icia n, 330 Crofts Hall,

of Oklahoma, Norman,

cal School, Rochester, Minnesota

dean of SUNY at Buffalo's School

U11 iversity at Buffalo, Buffalo,

Oklahoma

(the first department of immunol·

of Medicine and Biomedical Sci-

NY 14260.

ogy in the country I. Subsequently,

ences. (Dr. Wright was a Buswell

David Sackett, chair,

Department

director, Cancer Center, University

Fellow, working on amyloidosis

of Epidemiology, McMaster Univer·

of New Mexico; chair, Department

with Dr. Evan Calkins from

1965-1967.1

sity, Hamilton, Ontario. Currently,

of Cell Biology, University of New

chair of the Department of Epide-

Mexico, Albuquerque, New Mexico;

miology, Oxford University, England.

president/chief executive officer,

Alllllmll

2000

4D

l t ffa le Hys i c i u

11

�ST

0 R Y

By
S.

A .

UNGER

•

Obese
children
learn to
turn off
television

is helping obese children learn
to choose healthy behaviors.

�high-calorie foods are red and should be eaten rarely; moderatecalorie foods are yellow and can be eaten in moderation; and
low-calorie foods are green and can be eaten freely.
According to Epstein, obesity carries the same risks for children as it does for adults: an increase in health problems that
include diabetes mellitus, hypertension and high cholesterol. In
addition, obese children are at higher risk of remaining so as
adults. "Obese children who become obese adults have a very
difficult time losing weight and maintaining a normal weight;
only a very small percentage are successful over the long
run," he says. "So most researchers feel the best hope
is to catch kids early and try to prevent them from
becoming overweight adults."
As part of their ongoing effort to devise ways to
"catch kids early," Epstein and his group are currently conducting a study aimed at better
understanding how sedentary behaviors can be modified to treat and prevent obesity in children. In work
funded by a 1,050,688 grant from
the ational Institute of Child
Health and Human Development
( ICHHD) of the IH, the researchers are specifically interested in discovering ways to
modify a constellation of
sedentary behaviors that are
especially popular among
today's children: watching
television, playing video games
and surfing the Internet.

Sedentary Behaviors
Move to the Foreground

I

n describing the stair-step approach he and his
group have taken over the past 20 years to arrive at their
current focus on sedentary behaviors, Epstein
explains that their first studies- begun in the early 1980s at
the University of Pittsburgh-demonstrated the efficacy of

treating a child and his or her family together, versus just treating
the child separately.
From there, Epstein's group focused their attention on trying
to understand the role of physical activity in treating obesity.
"We started off with a review of the literature on activity, and it
suggested that lots of people who begin exercise programs do not
maintain them," he says. As a result, his group developed the idea
of "lifestyle exercise."
Instead of trying to get people to
adhere to a very high-intensity
exercise program, lifestyle exercise
encourages changes in everyday
behaviors; for example, parking
farther from a store entrance
and walking. In the early 1980s,
Epstein's group completed the
first randomized study done
on a lifestyle exercise program
and demonstrated that this
approach toweightlossworks
better than a traditional
exercise program.
Bythemid-1980s,
therefore, Epstein's
research had resulted
in the establishment
of innovative exercise and diet models
specifically geared to
treating obesity in the
pediatric population.
"About that time,
however, we started
to recognize that
even though lifestyle exercise and
diet were very useful, lots
of kids still preferred being
sedentary, so then we started to look at the competition-and
the competition, of course, was television," recounts Epstein.

THE RESEARCHERS ARE SPECIFICALLY INTERESTED IN DISCOVER!
TO MODIFY A CONSTELLATIO
POPULAR AMO

OF SEDE

G TODAY'S CHILDRE
GAMES A

TARY BEHAVIORS THAT ARE ESPECIALLY

:WATCH!

D SURF!

G WAYS

G TELEVISION, PLAY!

G VIDEO

G THE INTERNET.

A utum"

2 000

l 1ffal1 Pbysician

13

�This realization was based on pioneering work being conducted at that time by two Harvard researchers, William H.
Dietz Jr., MD, PhD, and Steven L. Gortmaker, PhD, who "were
the first to effectively argue that sedentary behaviors-television
viewing, in particular-were a risk factor in the development
of obesity," according to Epstein. They did this, he says, by
conducting studies that showed that sedentary behaviors
replace high-energy activities while at the same time promoting
increased caloric intake in response to commercials for food.

B

Behavior of Choice
ased on Dietz and Gortmaker's studies, Epstein became interested in the idea ofbehavior-choice theory,
and in the early 1990s he and his group began a
series of studies aimed at better understanding how
sedentary behaviors can be modified within the context of this
theory to treat and prevent childhood obesity. Again, the
sedentary behavior they were particularly interested in studying was television viewing because "it is estimated that by the
time children today graduate from high school, they will have
spent more time watching television than they spent in class,"
says Epstein.
"Behavioral-choice theory recognizes that kids have a choice
between two incompatible behaviors-they can either be active,
or they can be sedentary," explains Epstein. "Therefore, we
started to look at understanding how people allocate choicehow they decide to do things-and in working with behavioralchoice theory, one of the obvious things suggested by it is that if
two things are incompatible, you can either reinforce the one
you want, or you can reduce access to it."
Subsequently, Epstein set up a study comparing weight loss
between three groups: one reinforced for an increase in exercise;

1 ..

Buffa a Pbysicia1

A ut11m11

2 000

a second, for a decrease in sedentary activity; and a third, for a
combined approach. To reinforce behavior, contracts were set
up between the children and their parents that enabled the
children to earn points toward rewards that were activity based,
as opposed to money or food; for example, going to the zoo with
their parents.
The results of the study, published in Health Psychology in
1995, showed that the children who were reinforced for being
less sedentary- e.g., less television and fewer computer
games- had a bigger weight loss than the children who were
reinforced for increasing their physical activity. They also had
equal fitness changes and a better adherence to the diet
prescribed to all study participants.
This study, which was the first to manipulate access to
television, suggested "that at least this was an alternative
approach to trying to work on getting kids to be more active,"
says Epstein. In an effort to replicate these findings and better
understand how the children made their choices, Epstein and
his UB group recently completed a study titled "Exercise in the
Long-Term Control of Childhood Obesity," which was funded
by a $1,073,213 grant from the NICHHD. Participants in this
study were randomized to either increase physical activity or
reduce sedentary behavior and, in addition to keeping a log on
their exercise and food intake, they wore a beeper-size device
called an accelerometer that provided the researchers with data
about caloric expenditure.
"Again, we found that the group that reduced sedentary
behavior had substantial decreases in weight loss and improvements in fitness that were maintained over the two years we
followed them," reports Epstein. "We also found that in the kids
who reduced their sedentary behavior, about one-third of the
time they substituted the behavior with physical activity, which

�is exactly what we wanted. The other two-thirds of the time, they
substituted it with other sedentary behaviors."
Epstein emphasizes that the children were not being told
what they had to do; instead, they were being rewarded for
choices that freed up time for them to fill any way they chose.
"Everybody likes to choose what they're going to do, and they
are much more likely to change a behavior if they think it's
their choice," he says.
In 1997, Epstein and his group conducted a laboratory study
that confirmed this supposition: "We got much better results
for reinforcing children's behavior than restricting it," he says.
Two years ago, with these preliminary results in hand, they
began their current study, the goal of which is to look at different ways to reduce television that translates into different
kinds of outcomes. "We know that reducing a broad constellation of sedentary behaviors-especially TV-is useful in
treating obesity," says Epstein. "The study we're currently
conducting is designed to identify specific techniques we
might use to do that."
4D

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SCHOOL
Acceptance granted to qualified students
without regard to race, color, religion or
national origin.

�PATHWAYS

THE

Louis A. and Ruth Siegel Teaching Awards

FOLLOWING

The Louis A. and Ruth Siegel Awards are presented annually in order to

AWARDS

recognize the importance of superior teaching in the clinical and preclinical

were presented

years, as well as to encourage or1going teaching excellence. Recipients of the

at the Univer-

awards are chosen by students through a nomination process, with final
input from a committee comprising representatives from each of the

sity at Buffalo

school's four classes. Louis A. Siegel, MD '23, served as an assistant

School of

professor in obstetrics and gynecology at the University at Buffalo School of
Medicine and Biomedical Sciences for 21 years. In 1977, he and his wife,

Medicine and

Ruth, erJdowed the Siegel Excellence in Teaching A wards.

Biomedical
Sciences'
Annual Faculty
Meeting, held
onMay 24,
2000, in Butler

oversees and manages the school's

House Staff and
Special Awards

entire research operation and

Marsilia Seiwell, MD, GY lOB

graduate training program," said

Francis Whalen, MD, medicine

Dean Wright. "In addition to his

Pierre Giglio, MD, neurology

many other activities, Bruce is our

Gul Dadlani, MD, pediatrics

essential liaison with the provost's

Dilip Dan, MD, surgery

office, as well as with government

Dinesh Arab, MD, medicine

and industry."

Auditorium,

Anthony Mato, Class of 2002

Farber Hall.

Timothy Pardee, Class of2001

Stockton
Kimball Award

Dean's Award

ors a faculty member for academic

The Stockton Kimball Award honThe Dean's Award is given zn

accomplishment and worldwide

special recognition of extraordinary

recop1ition as an investigator and

service to the School

researcher. Stockton Kimball, MD
'29, was dean of the University at

MD, professor of medicine and

medical Sciences.

Buffalo School of Medicine from

chief of the Infectious Diseases

Wright presented the
award to Bruce Holm ,
PhD, senior associate
dean, in recognition

l uffall Hysician

1946 to 1958, and his

Division at Buffalo Veter-

contributions to the

ans Affairs Medical Cen-

training ofphysicians at

ter. Murphy was honored

UB spanned more than

for being an outstanding

a quarter of a cent!lry.

scientific investigator in

of his many contributions to the

The recipient of

school. " ot only does Bruce

this year's Stockton

maintain an extremely well-funded

Kimball

research program, but he also

16

Autumn

2000

Preclinical Award, Peter T. Ostrow, MD.
associate professor of pathology and
neurology (left); Volunteer Award,
Howard E. Sperry, MD, clinical assistant
professor of medicine (right); and
Clinical Award, RichardT. Sarkin, MD,
associate professor of clinical
pediatrics (seated).

of Medicine and Bio-

This year, Dean

H

s

Timothy

Award

IS

Murphy,

the field of microbial
pathogenesis who

hy

has received notable recognition

�for his development of vaccine

he has developed protocols for

antigens for ear and respiratory

antibiotic usage and has emerged

tract infections. In addition to

asaleadingadvocateinNewYork

his work at UB, Murphy has

for the appropriate management

served on numerous national

of infections.

study sections, review panels and
international committees.

In recent years, Brass has developed a strong interest in the
use of computers in support of

Berkson
Memorial Award

evidence-based medicine and has
generously given of his time to

The Robert S. Berkson, MD,
Memorial Award is presented
nn111Wily to honor the values nnd
ideals epitomized by Dr. Berkson,
who wns nn esteemed family physician in Buffalo. Patient wre wns
his forte; competence, compassion,
patience nnd dediwtion to teaching were his virwes. His expertise
in the "nrtofmedicine" is

teach residents how to research
information online.
For the past 10 years, Dr.

in this nwnrd.

Margaret McAloon, MD, associate professor of clinical medicine and pediatrics, was presented the University at Buffalo
School of Medicine and Biomedical Sciences' Humanism
Award at this year's White Coat Ceremony (see also page 24).
Nominations for the award are made by directors of the thirdand fourth-year clerkships. McAloon's nominator stated:

Robert Kalb has served as a

"I cannot think

member of the school's volunteer

of another faculty

faculty, integrating an active

member I have

private practice with an intensive
teaching schedule. Throughout
his career, Kalb has demonstrated
a remarkable knowledge

meant to be perpetuated

2000 Humanism Award

worked with who
has so gracefully
exhibited all the

of clinical and investiga-

characteristics

tive dermatology, which

typically demon-

The 2000 Berkson

he has used to provide

strated by the

Memorial Award was

exceptional patient care.

recipients of this

presented this year to

During the year, he

award

Corstiaan Brass, MD,

generously shares

[Dr. McAloon is]

lb

clinical associate professor of medicine, and

this knowledge by
conducting week-

Robert E. Kalb, MD, clinical asso-

ly dermatology conferences,

ciate professor of dermatology.

supervising residents and students

•

able to treat people
with sincere com-

MARGARET MCALOON. MD

passion, determine their physical, emotional and social needs, all while

Brass has been a model physi-

in dermatology clinics and giving

cian who willingly volunteers his

fourth-year students exposure to

teaching a large team of health-care professionals. Her style

time to teach at all levels of medi-

the practice of dermatology

seems effortless and is completely inspiring. She is also a

cine, a dedication that has won

through his office setting. &lt;Ii)

fantastic clinician because she has retained treatment modali-

him the respect of students and

-NANCY DRUAR

ties that may have been forgotten by most, but which consis-

colleagues alike. Over the years,

tently work for her patients. At the same time, she is completely
up to date on the newest proven treatment options. She is one

BRASS HAS BEE

A ~10DEL PHYSICIAN WHO WILL-

INGLY VOLUNTEERS HIS TIME TO TEACH AT ALL
LEVELS OF MEDIC INE , A DEDICATION THAT HAS

of those special people I hope to emulate as a physician,
teacher and mentor."
Support for the Humanism Award is provided by the
Healthcare Foundation of New Jersey.

&lt;Ii)

WON HIM THE RESPECT OF STUDENTS AND
COLLEAGUES ALIKE .

A

ll

t II Ill tl

2 0 00

luf f al • Phy si c i an

11

�PATHWAY

of the board of the

ew York State

sionary work in Botswana and

- LOIS BAKER

South Africa.

Children's Names CoChiefs for Pediatric
Gastroenterology
Robert D. Baker, MD, and Susan
S. Baker, MD, from Medical
University of South Carolina,
have been appointed co-chiefs of
the Division of Pediatric Gastroenterology, Hepatology and

u-

trition at the Children's Hospital

Chelikani V. P. Varma, MD {leh), has received the 2000 Pediatric Teaching Award
from the Pediatric Residents Association of Kaleida Health's Children'sHospital of
Buffalo. Varma, aclinical associate professor of pediatrics at the University at
Buffalo School of Medicine and Biomedical Sciences, maintains aprivate practiceD.L.C. Pediatrics-in Depew, New York. Pictured with Varma is Dawn M. Simon, MD
'98, president of the Pediatric Residents Association at Children'sHospital.

of Buffalo and professors of

atric gastroenterology and have served
as instructors in pediatrics at Harvard
Medical School.
Among

their

responsibilities at
Children's are the
administration and developm
of the hospital's Gastroenterol-

Buffalo School of Medicine and

ogy Laboratory, as well as

Biomedical Sciences.
The husband-and-wife team
earned their medical degrees from
Medicine and doctorate degrees

elected to the AMA's Council on

from Massachusetts Institute of

Scientific Affairs and sits on its ex-

Technology. They completed in-

research

on

cell

gastrointestinal
tract in pediatric
patients. Their clinical interests include
nutrition, dysmotil-

ielsen, MD '76, PhD,

ecutive committee and Strategic

ternships in pediatrics at the

assistant dean for student affairs

Planning Task Force. She also cur-

Children's Hospital of Buffalo in

medicine and infec-

at the University at Buffalo School

rently serves the AMA on the la-

1973, after which they spent three

tious disease.

of Medicine and Biomedical

tional Patient Safety Foundation

Sciences and a clinical associate

Board of Directors and the Com-

professor of medicine, has been

mission for the Prevention of

elected vice speaker of the Amer-

Youth Violence. In the past, she

ker

has served on the AMA 's

Medical Imaging
Team Wins Top Pri:ze

tion's policy-making

Ad Hoc Committee on

A University at Buffalo team

who received a doctorate in ra-

House of Delegates.

Structure, Governance

won the prestigious Blue

diation physics from UB this

ican Medical Associa-

If tradition holds,
the election places

and Operations.

iel-

Currently,

ielsen

Ribbon Award at the SPIE

year. Other members of the

International Symposium on

team were Stephen Rudin , MD,

sen in line for the presi -

serves as the speaker of

Medical Imaging held in june

co-director of the Toshiba

dency of the AMA,

the House of Delegates

2000. The group received the

Stroke Research Center and

according to an

of the Medical Society of

award for a research presenta-

director of the Division of

AMA spokesper-

the State of

ew York.

tion describing a new medical-

Radiation Physics, and Daniel

son who explained

She has served as a trustee of the

imaging technique developed

R. Bednarek, PhD, associate

that, in the past,

State University of

ew York

at UB that could lead to im-

professor of radiology and

the vice speaker has assumed

and chief medical officer for the

proved diagnostic imaging us-

research associate professor of

ew York State Department of

ing lower doses of radiation.

neurosurgery and physiology

Health's Western Region, and is a

Primaryauthorofthestudywas

and biophysics.

Nielsen, an internist in private

fellow of the American College of

Parinaz Massoumzadeh, PhD,

practice in Buffalo, has twice been

Physicians and a former member

the speaker's role, and the speaker has been elected president.

l•lfal• Hysiciu

Alltlllllll

2 000

ker

function within the

ity, complementary

Nancy II.

t 8

Both are board certified in
pediatrics and pedi-

pediatrics at the University at

Temple University School of

Nielsen Elected Vice
Speaker of AMA

years performing hospital mis-

Society of Internal Medicine.

fD

j

�McKinley Assassination [xamine~
By J a c k C. Fi sher , MD '6 2

VERY PRESIDENTIAL ASSASSINATIO

~
.;
=

~

~
=
~

%

..

u

r

..
~

-

-;

.
.
=
~

!
u
c

::

m United ballistic advisory, I have relied primarily on my uncle, Jack
States history has prompted its own conspiracy theory and led Anthony, a retired engineer with a lifelong interest in historic
to public rebuke of the physicians who tried to save their firearms. His theory was a "short load," which means that the
patient. Indeed, following President McKinley's murder in 1901 cartridge was deficient of gunpowder and never reached its full
the public was skeptical that any individual could act alone to speed or force. His suggestion was to weigh the residual ammuundertake such an anarchical deed, and the late president's nition retrieved from Czolgosz's weapon. Other cartridges might
also be short of their gunpowder load .
surgeons were eventually censured by
CzoLGosz ONLY GOT Two
With the cooperation of William Seiner
laymen and professionals alike.
SHOTS OFF BEFORE HE WAS
and William Mayer at the Buffalo and Erie
o evidence of a conspiracy was ever
SUBDUED. HIS WEAPON
County Historical Society, the unexpended
found; like so many assassins, Leon Czolgosz
WAS
DOUBLE
ACTION,
AND
cartridges from the assassin's revolver,
acted as a solitary influence on history.
HE
SHOULD
HAVE
BEEN
together with the two fired cartridge cases
Whether or not the surgeons deserved the
ABLE TO EMPTY HIS GU:--: IN
and the deflected bullet, pictured below, were
criticism they received is the principal issue
THREE TO FIVE SECONDS.
taken to the laboratory of Bruce
that I will deal with in a forthcoming book
Actual gun used in
\NHY DIDN'T HE?
Holm, PhD, senior associate dean
about the McKinley assassination (Stolen
the assassination
in the School of Medicine and
Glory, due out in the spring of 2001 ).
of President
Other questions have arisen during my research. Czolgosz Biomedical Sciences. Weights were recorded on a gram
McKinley; held in
patterned his attack on the 1900 assassination of Italy's King scale accurate to four decimal points.
the collection of the
The results clearly showed that one of the unused
Humbert. He purchased at a Buffalo hardware store a weapon
Buffalo and Erie
identical to the one used against Humbert, a 5-shot .32-caliber cartridges was short of its full load of gunpowder, lending
County Historical
Iver-Johnson revolver. Whereas King Humbert's assailant was support to the theory that one of the two spent cartridges
Society.
able to fire four times,

-

r
I

..

Czolgosz got only two shots off
before he was subdued. His weapon
was double action, and he should have been able to empty his
gun in three to five seconds. Why didn 't he?
Furthermore, only one of the two bullets penetrated the body;
the other bounced off the breastbone, resulting only in a superficial
contusion of the skin. A .32-caliber revolver in 1901 could develop
a bullet velocity of 700 feet per second and a muzzle force of 100
foot-pounds, more than enough to pierce the sternum and inflict
serious damage to the chest cavity. Why didn't that happen?
Shortly after the attack, a Buffalo police officer suggested to a
reporter that one bullet likely failed because it was defective. For

was also defective. Presumably, Czolgosz had purchased
ammunition with significant manufacturing variations.
One can speculate that if the assassin had emptied his revolver into
McKinley's body, only three of five bullets would have penetrated.
Why weren't all five shots fired? The best guess of experts I have
polled is that the revolver's external hammer became entangled in
the handkerchief that Czolgosz used to conceal his weapon. As the
assassin went down, his right hand still held the revolver aimed at
McKinley, but no more shots were heard.
4D
Jack Fisher, MD '62-who will write a more extensive article on this
subject for an upcoming issue of Buffalo Physician-is an emeritus
professor of surgery at the University of Califomia at San Diego,
where he is wrrently a master's candidate in U.S. history. Readers
with questions or comments can e-maillzim at jfishermd@aol.com.

�R

20

IUffliD

E

Pbp i c i ln

E

A

R

C

H

Autumr~

N

2000

E

w

�Hypertension
Redefined

hypertension is the most prevalent risk factor in heart failure,

inversely related to cardiovascular risk."

mutations due to exposure to
X-ray or to anything potentially

joseph Izzo, MD, University at

stroke and kidney failure," he

Additional authors on the

Buffalo professor of medicine and
pharmacology and vice chair of

explains. "It is clear that lowering
systolic pressure is associated with
better outcomes in cardiovascu-

study were Daniel Levy, director
of the Framingham Heart Study

carcinogenic that mimics X-ray
damage, such as many chemicals

research for the Department of
Medicine, was lead author of a
National Institutes of Healthsponsored
clinical advisory statement
released in
May stating

..

that systolic
blood pressure is the
important
factor in

lar and renal disease.
"Systolic hypertension interacts with other
major risk
factors, such
as high cholesterol and
diabetes,
which also
increase
with age,
to amplify
the age-re-

of the National Heart, Lung and
Blood Institute, and Henry R.
Black, Roberts Professor and chair
of the Department of Preventive
Medicine, and associate vice
president for research at RushPresbyterian-St. Luke's Medical
Center in Chicago.

4D

-LOIS BAKER

BloodTest
Measures
Radiation Damage

determining
whether a person has hypertension-not diastolic blood pres-

lated risk of
cardiovascular events," he adds.
Isola ted systolic hyperten-

Scientists from the University at
Buffalo have developed and
patented a simple blood test that
can measure accumulated cell

sure, as traditionally thought.
Making systolic blood pres-

sion-defined as systolic pressure

damage from ionizing radiation

at or above 140 mm/Hg and dias-

long before any physical signs

sure the major criterion for diag-

tolic under 90 mm/Hg-is the

are evident.

nosis, staging and therapeutic

most common form of hypertension and is present in about

management of hypertension,
particularly in middle-aged and
older Americans, represents "a
major paradigm shift," the
advisory states. It also calls for
more vigorous control efforts
and for abolishing the use of ageadjusted blood-pressure targets.
"This shift affects 25 million
people in the United States whose
lives can be improved by the
change," says Izzo, who adds that
much evidence points to systolic
pressure as the critical factor in
determining the risk of heart
disease. "For example, systolic

two-thirds of people over the age
of 60 with diagnosed high blood
pressure, according to Izzo.
Using diastolic blood pressure to define hypertension in
persons middle-aged and older
actually misrepresents the risk of
potential heart problems, he
notes. "Systolic blood pressure
increases steadily with age in industrialized Western societies,
whereas diastolic blood pressure
increases until about age 55 and
then declines. So in older persons, diastolic blood pressure is

The testcalled the
Transferrin
Receptor
Red
Cell
Assay, or
"E-Trassay"
-was developed by

used in the microchip industry.
"This test provides a way to
measure damage before the first
sign of cancer appears," Gong
explains. "It also can determine if
cell mutations from ionizing
radiation are increasing
over time. If so, an indi- The test-which
vidual can take steps to requires adrop of
stop the increase, per- blood and about two

hours for
analysis-can be
taken as often as
desired, SO
subsequent blood
tests can monitor
any
increase or
patients who have redecrease in cell
ceived radiation treatdamage.

haps through a change in
job, diet or environment.
It gives people more control over their health."
Potentially, the test
could also allow cancer

ment to reconstruct their

past radiation doses, as
well as project the
amount of residual injury
that will exist
in the future,
Gong adds.
It could also
be useful for
determining
exposure to
ionizing radia-

Joseph K.
Gong, PhD, as-

tion emitted by
cellular phones,

sociate professor
emeritus of oral diagnostic sciences and chair of UB's Radioisotope Safety Committee.
Using a specific biomarker, it reveals the extent of stem cell

microwave ovens and
computer screens.

CONTINUED ON

PAGE

22

SCIENTISTS FROM THE UNIVERSITY AT BUFFALO HAVE DEVELOPED AND PATENTED A SIMPLE
BLOOD TEST THAT CAN MEASURE ACCUMULATED CELL DAMAGE FROM IONIZING RADIATION
LONG BEFORE A Y PHYSICAL SIGNS ARE EVIDENT.

Autumn

2000

I u f f al o Physic i a a

21

�RESEAR

~NTIN U ED

FR O M

PA G E

2 1

Gong and his co-investigator,
Chester A. Glomski, MD, PhD,
professor of anatomy and cell
biology, were able to show that
radiation exposure causes stem
cells to express an excess of
erythrocytes that bear receptors
for the protein transferrin on their
surface membrane. Knowing this
cause and effect, it then became
possible to use the number of red
blood cells with transferrin receptors as a biomarker for
radiation exposure. The test0

.."
..

which requ ires a drop of blood
and about two hours for analysis-can be taken as often as
des ired, so subsequent blood
tests can monitor any increase or
decrease in cell damage.
Also par t icipating in the
research was Yuqing Guo,
biophysicist and research scientist at Biomira USA, Inc., in
Cranbury,

ew Jersey.

4D

-LOIS BAKER

Another Piece to
Insulin Pu:z::z:le
In addition to enabling cells to
absorb sugars, insulin is also known
to dilate blood vessels, an action
that is a boon to the heart because
it allows blood to flow more easily
and under less pressure. Precisely
how this vasodilation occurs is a
puule. But researchers have shown
that when insulin comes into con-

C

N

H

E

w s

tact with cells in the blood-vessel
lining, it induces the release of

rise above baseline in the amount
of enzyme.

nitric oxide, a known blood-

In addition to providing new

wider application than previously
thought, new research by University at Buffalo faculty has shown.

information on the mechanism un-

Thomas S. Mang, PhD, UB

Endocrinologists from UB have

derlying insulin's vasodilatory ef-

clinical associate professor of oral

vessel dilator.
now supplied a new piece to this

fect, these findings give insight

and maxillofacial surgery, has

puule by showing for the first time

into the relationship between hard·

found that by manipulating the

that insulin causes cells in the

ening of the arteries and insulin

amount of a light-sensitive drug

blood-vessel lining to increase se-

resistance/diabetes, conditions

and the intensity of the laser beam

cretion of nitric oxide synthase,

that often exist in tandem. "The

that activates it, he can successfully

the enzyme responsible for nitric
oxide produc-

lack of insulin or resistance to
the action of insu-

treat cancer cells deeply embedded

lin will cause

ing surrounding normal tissue. In

tion.
"This

in the chest wall without damag-

the vessel

a study recently completed by

new ob-

constriction

Mang and Ronald R. Allison, MD,

servation

and increase

UB associate professor of clinical

is impor-

aggregation

radiation oncology, this low-dose

tant

be-

cause

of

it

platelets

PDT approach resulted in com-

known to occur

plete healing in nearly 90 percent

provides

in diabetes mel·

of 102 recurrent breast-cancer

the molecu-

litus," Dandona

lesions found in nine women who

lar basis for the
known vasodilatory

explains. "Fur-

had undergone surgery, fulldose radiation and chemotherapy.

effects of insulin," says Paresh

thermore, the fact that
nitric oxide also may reduce the

Dandona, MD, UB professor of

expression of adhesion molecules

proof of the ability to lower drug
concentrat ions and raise light

"These results offer further

medicine, who conducted the re-

on the surface of cells lining blood

search in collaboration with gradu-

vessels may prevent cells from

intensity to successfully treat

ate student Ahmad Alijada.

adhering to the vessel lining. This

certain difficult tumors, " says

By introducing insulin into aor-

adhesion is one of the initial

Man g. " It allows broader applica-

tic cell cultures in increasing con-

events in arterial hardening

tion of this therapy in patients

centrations from 25 to 1,000

and blockage."

who can truly benefit from it. "

microunits per milliliter for a total

-LOIS

BAKER

of six days-amounts similar to
what would occur normally and in
patients with obesity and type 2
diabetes-the researchers showed
that nitric oxide synthase increased
as the amount of insulin increased,
with the highest concentration of

PDT, which was developed at
Roswell Park Cancer Institute, the
site of UB 's basic cancer research

New Light on
Cancer Therapy
Pho todynamic therapy, or PDT,
one of the most promising new
cancer treatments, may have much

insulin resulting in a 250 percent

programs, exploits the propensity
of cancer cells to absorb higher
than normal concentrations of
photosensitive drugs. When exposed to light via lasers, these drugs
become toxic and destroy the malignant tissue. Since normal tissue

searc
22

luflalo Phys i c i u

Autumn

2 000

surrounding tumors also absorbs
a certain amount of the drug, the
goal of researchers and clinicians
is to find a drug-to-light ratio for
each tumor type that will kill the

�most tumor cells while sparing the

Medi-

Cancer Center;

veys, restaurant-employment

most normal tissue.

cine

..-:::::::;;;;;;;;ii~~[FI!iljl=::;:;;;;'==-':::~:§::; University of

statistics and complaint reports .

In the current study involving

t h a t

Pittsburgh;

A review of taxable sales

breast-cancer lesions that had

there

University of

showed no effect on sales from

"'0

formed on the chest wall, Mang

was no dif-

Utah; Wake

smoking restrictions in restau-

,.

lowered the standard 2.0 mglkg

ference in there-

Forest

rants in dozens of communities

dose of the photosensitive drug to

currence of pol-

School

in New York, California, Colo-

of

0.8 mglkg. "If we used the standard

yps between the

Medicine; Walter

rado, Massachusetts, Arizona,

drug dose, we never would have

diet intervention group and a con-

Reed Army Medical Center; Veterans

and Texas, he found. In addition,

been able to use a light dose that

trol group that didn't change diets.

Administration Medical Center (Hines,

bar revenues in California in-

would reach deep enough to kill

Peter Lance, MD, associate

Ill; and Kaiser Foundation Research

creased 6 percent 12 months

the tumor cells without destroying

professor of medicine and physiol-

Institute (Oakland, CA).

normal tissue," he explains.

ogy, and principal investigator on

-LOIS BAKER

"By lowering the drug dose,

&lt;D

was disappointed but not alto-

normal tissue bleaches out before
it does any damage, and by

gether surprised by the negative
results. "The study is consistent

after smoking was restricted .
Consumer surveys conducted
in New York City at five months

UB's portion of the trial, says he

the small amount of the drug in

and 18 months after passage of the

Smoke-free
Restaurants,
Healthy Restaurants

delivering more light, we can

with the findings of previous

reach deeper into tumors where

smaller trials and of another large

Restricting smoking in restaurants

the drug concentration is still

trial-the Wheat Bran Fiber

has not been a recipe for econo-

high enough to kill cancer cells.

Study-published in the same

mic disaster for the restaurant

"These results offer a glimpse of

issue. Clearly, dietary change does

business, despite predictions to

the parameters one might be able

not make you less likely to develop

the contrary, a University at Buf-

to use for treating whole fields of

new polyps after you've had all

falo epidemiologist has found

disease with little normal tissue

existing polyps removed.

following review of existing data.

ew York City Clean
Air Act indicated that

"Studies showing
adverse
conse·
the vast majority of
quences typically
consumers dined out
are flawed, relying
as often after the law
on survey data or
as before. "Analyses of
anecdotal repons.
restaurant-employment
Our analysis shows
statistics indicated that
that the restaurant
more restaurant jobs
business remains
were added in New healthy after smoke·
York City two years free dining policies
after the law went into are implemented."

damage," Mang says. "It gives us

"What the study does not ad-

"Virtually all" published stud-

good local control of disease." &lt;D

dress-and was not designed to

ies on the issue show no adverse

address-is what the environment

effect in restaurants, hotels and

of the colon should be to reduce

bars, regardless of the study

effect than the rest of
ew York State where smoking

the likelihood that small, innocent

method used, says Andrew

was still permitted," Hyland

polyps will grow to become can-

Hyland, PhD, research assistant

reports. In Erie County,

cers," he notes.

professor of social and preventive

per-capita restaurant employ-

-LOIS BAKER

Polyps Unaffected
by Healthy Diet

Y,

Adopting a diet low in fat and high

The researchers also noted

medicine, who recently presented

ment increased faster than in six

in fruits and vegetables may have

thatdespitetheirfindings, the idea

his findings at the International

of seven surrounding counties

many health benefits, but lowering

that a healthy diet may lower the

Society for Environmental Epi-

where smoking was permitted, 12

the risk of developing recurrent

risk of colon cancer should not be

demiology meeting. "Studies

months after a county law went

colon polyps-precursors of colon

entirely discarded. Several fac-

showing adverse consequences

into effect. "Also, few people are

cancer--does not appear to be

tors, including study length and

one of them.

potential reporting errors, could

typically are flawed, relying on
survey data or anecdotal reports.
Our analysis shows that the res-

complaining about the law,"
Hyland notes.

taurant business remains healthy
after smoke-free dining policies
are implemented."

public health issue," says Hyland.

Investigators from the Univer-

have influenced this study's re-

sity at Buffalo's School of Medicine

sults, Lance says. In addition, such

and Biomedical Sciences and the

a diet is known to have a favor-

seven other centers involved in the

able impact on cardiovascular dis-

:

"Secondhand smoke is a serious
"Policymakers need to understand
that adverse economic claims

five-year national Polyp Prevention

ease and other chronic conditions.

Hyland examined published

Trial reported in the April20, 2000,

Other sites involved in the study

studies examining taxable sales,

tion are unsubstantiated."

issue of The New England Journal of

were Memorial Sloan-Kettering

consumer and restaurateur sur-

-LOIS BAKER

A11t11mn

resulting from smoke-free legisla-

2000

&lt;D

l 1ffaf1 Hysiciu

23

�M

E

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L

ScHOOL

E

W

S

First Biomedical Sciences Career Day
G R ADUATE STUDENTS FROM

and faculty, as well as from rep-

Health, Schering Plough, Ros-

the University at Buffalo School

resentatives from the law firm

well Park Cancer Institute.

of Medicine and Biomedical

of Hodgson, Ross, Andrews,

Sciences, the Departments of

The program included a key-

an opportunity for one-on-one
interactions. Roundtable discussions on specific career paths

Woods and Goodyear, the

note address by Claire Lathers,

were also held with panelists

Oral Biology and
Pharmaceutics, and

Centers for Disease

PhD '74, FCP, director of the

Ranjana Kadle, PhD, JD; Gary

Control,

DuPont

Office of New Animal Drug

Giovino, PhD; Sarita Chauhan,

Roswell Park Cancer

Central

Research

Evaluation, Center for Veteri-

PhD; John Simich, PhD; Lyn

Institute attended

and Development,

nary Medicine, U.S. Food and

Oyster, PhD; Wilson Great-

the First Biomedical

Erie County Central

Drug Administration. Her lec-

Sciences Career Day

Police Services For-

ture was followed by a series of

batch; Mark Connors, MA;
jacques Berlin, PhD; Michael

on May 31, 2000, at

ensics Laboratory,
the Food and Drug
Administration, Gen

short talks by Robert Genco,
DDS, PhD; Allen Barnett, PhD;

Vladutiu, PhD; and james

David McCann, PhD; and

Hernandez, PhD. The day end-

learned about successful strate-

Cyte, LLC, the National lnsti-

Wade Sigurdson, PhD. During

ed with a reception that includ-

gies for career development and

tute on Drug Abuse, the

ew

lunch, students were seated

ed more networking with the

management from UB alumni

York State Department of

with the invited guests to foster

invited presenters.

the Buffalo/ iagara
Marriott. Students

CLAIRE LATHERS

Morales, PhD; Georgirene

4D

Wh"te Coat Ceremony
MEGAN MOORE OF P ITTSFORD,

Y,

being "cloaked" at this year's White Coat
Ceremony by Daniel C. Kozera , MD '59, a
board member of the Medical

Alumni

Association . The annual ceremony-a
symbolic rite of passage for beginning
medical students to help them establish a
ps ychological contract for professionalism and empath y in the pra ctice of

.
...
.

medicine-is sponsored by the Medical
Alumni Association a nd The Medical

L

School Parents' Council.

0

The keynote speaker at the August 11
event was Robert Milch, MD, director for

z

the Center for Hospice and Palliative
Care in Buffalo, whose talk will be featured In the winter
issue of Buffalo Physicia11.
Following Dr. Milch 's lecture, Margaret McAloon , MD ,

class is 23 . Their average science grade point average is 3.53 and

was presented the " Humanism in Medicine Award " (see page

mean MCAT, 9.60. Fifty-seven of the students are male and 79,

17 ) by Charles Severin, MD, PhD, assistant dean for students.

female. Ten hold master's degrees and 113 were science majors.
Seventy-five are from Western New York.
-S. A. Ur-;cE R

Thomas Guttuso, MD, assistant dean of admissions, then
introduced each of the students while they were being cloaked.

24

For the Class of 2004, there were 1,987 applicants; of those,
463 were interviewed and 136 accepted. The average age of the

l a lfa le Ph ysi c i aa

Alltllmll

2000

�I

AUTUMN

2000

llorls Albini, profe-r
of microbiology

Elmer ......._11, medical

computlntfpl.....r

A1&lt;tumn

2000

1111111 ,.pic l u

Z5

�S

B
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S

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L

U

M

lonely for aCalling of My Own
Clinical r otations i nc l ude an exercise i n int r ospect i on

OR MOST MEDICAL

stu-

dents, the clinical experience of the third year
is like a carrot held out
to entice them
through

the

heavily didactic
first two years.

their conviction, I also realized I was lonely for a
calling of my own.
Gradually, my fear of third year began to mingle
with a sense of anticipation for the opportunity I
would have to experience each medical field. I
decided that the best way to make peace with what
lay ahead was to view it as a sort of exercise in
introspection. I would fully immerse myself in each
of the six rotations: internal medicine, psychiatry,
pediatrics, surgery, family medicine, and obstetrics/
gynecology. I would try on every hat and see which
one fit. Surely only one would flatter me, and the
rest would look obviously ridiculous.

But I quietly
dreaded

the A Possible Cure , but No Patient

transition.
After all, with almost 20 years of
experience sitting
behind a de k, I
was good at being
a student. I had
become quite comfortable in Butler
Auditorium, twothirds of the way
back, slightly left
of middle. I loved
all the zebra diagnoses and esoteric
nuggets of information and could not imagine what lured people
from the top of this ivory tower to the bottom of
the hospital totem pole.
Furthermore, I still wasn't sure which specialty I
wanted to pursue, and this ambiguity added to my
sense of unease. I envied (and frankly distrusted)
those characters who knew they were fated to be
urologists or neurosurgeons. As much as I doubted

26

luffall Pbysicill

A utumn

2 000

I

showed up for the first day of internal medicine
dressed sharply, not yet realizing the perils of
uncomfortable shoes. My short white coat was
brilliantly clean. To give the illusion of experience, I
had forced in a few wrinkles and had stuffed the
pockets with trusty reference books.
My memory of the first week of internal medicine
is a disconnected series of flashbacks. There was a
lot of wading through lab results- random numbers
that I knew were supposed to mean something to
me. I couldn't have told you the cause of my patient's
microcytic anemia, but I at least made sure that I
knew his TIBC by heart. Did medicine really consist
of merely juggling consults and labs? This was not
the glorious career I had had in mind when I wrote
my application essay for medical school.
One of my new patients had a concerning set of
symptoms: night sweats, weight loss, documented
daily fever spikes and anemia. The team was "working
him up"-a phrase that, at the time, seemed so
aggressive to me. He had already had a history and
physical, and although it seemed pointless, I knew I
would have to repeat them.
I dutifully palpated the thyroid, assessed the trachea for mobility and checked for tactile fremitusjust as I had learned in Butler Auditorium. On and on

�fURTHERMORE,

I

STILL WASN'T SURE WHICH SPECIALTY

AMBIGUITY ADDED TO MY SENSE OF UNEASE.

I

I

WANTED TO PURSUE, AND THIS

ENVIED (AND FRANKLY DISTRUSTED) THOSE

CHARACTERS WHO KNEW THEY WERE FATED TO BE UROLOGISTS OR NEUROSURGEONS.
AS

I

DOUBTED THEIR CONVICTION, I ALSO REALIZED

I went with the esoteric details of the physical exam,
feeling for epitrochlear lymph nodes and frustrated
by the amount of time I was wasting. Then, much to
my surprise, I felt something in my patient's axilla.
Yikes, a 4 x 5 em axillary lymph node. (At least I thought
it was a lymph node, since I had never
actually felt one before.)
"Sir, you seem to have a lump here. Have you
noticed it before?"
I proudly reported back to the team that I had
found the lymph node-not the attending, not my
resident, not my intern, but me, the lowly third-year.
So this was medicine!
As I arranged for the needle aspiration, I thought
about how we were going to get to the bottom of his
symptoms, discover his diagnosis and cure him.
When we told the patient that we wanted to stick a
needle into him, he promptly left the hospital against
medical advice. I couldn't believe the team would let a
seriously ill person just walk away.
"He'll be back," they said.
Medicine was not all brilliant diagnosis and
glorious cure after all.

The Missing Glasses

P

sychiatry was quite a change. Every day I faithfully
rounded up the latest Jab values, but my reports on
anemia were always met with statements like, "Yes,
yes, but how has he been sleeping?" I was surprised by
how much effort it took to detach myself from the
numbers and actually pay attention to the patient.
When had I gotten so comfortable with labs?
What struck me about my psych rotation was the
malleability of the human mind. Until I had spent
seven weeks in a locked psychiatry wing, I had always
assumed that one's personality was a fixed thing. I
had friends who were moody, others who were cheery,
and that was just how they were. But I was amazed by
the phenomenon of the "titrateable" personality and
marveled at watching rational minds emerge from
once fully psychotic people.

I WAS LONELY FOR A CALLING OF

I especially remember one of my patients, who
arrived in a comatose state. I thought he must have
been suffering from a hopeless neurological disability, but we kept on with the medications. One
morning I walked in and saw him eating breakfast,
and the nurse told me he had been asking for his
glasses. For the first time, I saw that some diagnoses
take time to emerge and cannot be elicited by strictly
objective measurements.

As MUCH
MY OWN.

I would fully immerse
myself in each of the
six rotations: internal
medicine, psychiatry,
pediatrics. surgery.

An "Old Hand" Draws Blood

N

ext on the Jist was my pediatrics rotation, where I
met a five-year-old boy named Alex (not his real
name) who was already in the hospital when I
arrived and remained there throughout my inpatient
rotation. After a while it seemed totally normal to
see Alex playing in the conference area during afternoon rounds, and we all took turns wheeling him
around the floor in his wagon. Somehow, the oddity
of his continuous presence wore off, and I grew
to think he was a normal boy who just happened to
live at Children's Hospital.
One day, Alex wanted to play a new game. Someone had given him a needleless syringe, and he said,
"Let's pretend I'm gonna draw your blood!" A little
macabre, I thought, but why not? Alex tied a tourniquet around my arm, and I winced at the squeeze. "It's
gotta be tight!" he said in a mock adult voice. Next,
uncoached, he expertly wiped down my forearm with
an alcohol pad, then began slapping my arm to bring
out a vein. "There's a good one!" he said in his doctorvoice, while pressing the syringe up against my arm
and directing, "Hold still, I don't have enough yet."
I couldn't help but laugh at this parody, but
underneath I was horrified by his impression of the
medical field. We were trying to heal Alex, but all he
knew was that he had been kept away from his family
for months, and every day he had blood drawn. It was
disillusioning to realize that your most idealistic
intentions are not always perceived as such.
The last I heard, Alex was still in the hospital.

Autum11

2000

family medicine. and
obstetrics/gynecology.
I would try on every hat
and see which one fit.
Surely only one would
flatter me, and the
rest would look
obviously ridiculous.

l off a le Pb ysician

27

�S

l

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T

COLUMN

WAS IN AWE AS MY ATTENDING SPOKE WITH HER. HIS COMPASSIONATE QUESTIONS ABOUT

THE DEATH OF HER HUSBAND AND HER CURRENT FI

ANCIAL SITUATIO

WERE A

TREATME T AS VALID AS ANY PILL OR SCALPEL.

History in the Making

H

y the time I began my surgery rotation, I felt like I
had figured out the routine. I had given up carrying references in my pockets, I spent all my time in
comfortable scrubs and clogs, and the wrinkles in my
white coat were legitimate. I also knew I could take the
sleepless nights, the lack of food, and the scut work.
Even though I had been duly warned by my classmates
about this rotation, I was looking forward to it: Surgery was going to be great.
My first days in the OR were indeed thrilling. I
loved scrubbing in, and I loved pulling off
the mask after we had closed up. This was
Your Turn?
better than watching ER!
If you are a student
After a while, however, the physical and
emotional demands set in. One case was paror resident interested
ticularly arduous: a deep abdominal procedure
in contributing to this
on an obese patient. I had a large Deaver retraccolumn in future
tor in each hand, and my chief still couldn't get
issues of Buffalo
a clear look at the field. He told the circulating
Physician, e·mail
nurse to find a St. Mark's retractor. Why did that
sound so much like a torture device from the
bp·notes@buffalo.edu
French Reign of Terror? The nurse handed me
to suggest a topic.
the oddly shaped tool and warned me that it
was notoriously difficult to hold.
The operation lasted six hours. As I stood holding
the retractors, I tried meditating on whether it was
possible to experience a higher level of pain in my
arms. It was not. Mostly, I was terrified that I would
contaminate the field with the proverbial bead of
sweat that was working its way down my brow.
At the end of the case, my chief turned to me and
said, "That may be the second time in history that a
medical student has held a St. Mark's retractor for
so long without complaining. The first time was
when I did it."

Better Than a Pill or a Scalpel

M

oving on to family medicine after surgery was
quite a shock. At first, I admit, I fought the gentle
nature of the family practice appointment. It's

just not humane to expect medical students to change
pace so drastically.
One day after I had begun to settle into my new

28

l alfale Hpiciu

Autumn

2 000

routine, I went to the door of my next patient and
picked up a thick chart, labeled "Volume II." After
introducing myself to the patient, I tried to do a
review of systems and to assess the state of each one of
her many ailments, but I kept meeting with resistance. From my perspective, it seemed like she really
didn't want to talk about her physical health at all.
When I tried to present this patient to my
attending, he smiled and said, "Let's go in and see
her together." I had been told about therapeutic
touch and the "art" of medicine, but nevertheless I
was in awe as my attending spoke with her. His
compassionate questions about the death of her
husband and her current financial situation were a
treatment as valid as any pill or scalpel.
After we closed the door behind us, he said,
"Sometimes you just have to know your patients."

The Totem Pole and the Hat Rack
s I write this article, I am completing my final
rotation, obstetrics and gynecology. The other
day, one of my classmates was talking enthusiastically about his experience in the rotation.
"So, have you delivered any babies yet?" I asked.
"Oh no," he replied, "but yesterday they let me
deliver a placenta!" It's funny how you learn to be
content with your place on the totem pole.
Much to my surprise, this year that I dreaded is
coming to an end. Despite what I've learned, I still
don't know which field to pick. All the hats have fit,
more or less. o one ever told me the choice would
not be obvious, that fate would not present me with
the answer as I had expected. There is an active
decision-making process, and I can see now that
whichever field I choose, it will involve sacrificing
what I value in other fields.
Lately, I've narrowed down my wardrobe to two
hats. Every day I look in the mirror and try to figure
out which one looks better on me.
4D

A

Umut Sarpel is currently a fourth-year student at
the Unil'ersity at Buffalo School of Medicine and
Biomedical Sciences.

�DEVELOPMENT

N

E

w s

(ndowments Crucial to School's future
By Li nda J . Cor de r • PhD. CFRE

-- ( - - c s
for the current "Campaign fo r UB: Generation to
Generation" is to increase its endowment significantly.
Establishing new endowed funds, adding to existing
endowments and growing the principal through
prudent investing-coupled with a sound spending
policy-are all ways to increase the value of the overall
endowment and to ensure the future of our school's
mission and vision.
Some of the School of Medicine and Biomedical
Sciences' most cherished traditions germinated from
dreams of our forebea rs whose gifts formed the core of
its present endowment. With both private and public
roots, our school benefits from a combined endowment
that generates funds to support, in perpetuity, designated
programs of the institution.
One of the school's earliest endowments was a gift
from Devillo W. Harrington. He
was wounded during the Civil War
ONE OF THE
and brought to Buffalo General
SC HOOL 'S EARLl Hospital, where interns from UB
ES T E •oQ \VM EN TS
treated his wounds. He recovered,
WA S A GI FT FROM
remained in Buffalo and went to
D EV ILL O \V.
medical school, graduating in
H AR RI:-&lt; GTO !&lt;. H E
1871. In honor of the 25th anniWAS WOU :-&lt;DED
versary of his graduation in 1896,
DURING THE CIVIL
he established an endowment. For
\\fAR AND
more than a century, the HarringBRO UG HT TO
ton Lectureship has brought outBuFF ALo G E =&lt; ERA L
standing medical scientists to
H o s P 1 T AL, w H E R E
Buffalo. Many others added gifts
1 NT ERN s FRoM U B
to the school 's endowment, of
TR EATED H 1 s
which the most significant to date
wo uNDs .
is the Hochstetter Fund for
Medical Research . Mr. Ralph
Hochstetter, president of Cliff
Petroleum, died in 1955, leaving UB a multimilliondollar bequest for scientific research. This endowment
provides annual support for the Bertha H. and Henry
Buswell Postdoctoral Fellowships, a program that

underwrites up to three years of support for each of
several young researchers in the biomedical sciences.
Today, that endowment provides over $20 million a
year-more than the original bequest.
Endowment is crucial to the school's future. Thus,
the development team spends a great deal of time facilitating new endowment gifts and providing information
to donors of endowed funds about the programs they
support and the financial status of the funds. Looking at
the school's overall budget, annual gifts and endowment gifts are small, but significant- and increasingsources of income. Endowment income provides
perpetual funding for either general unrestricted use by
the dean (extremely important) or for
specified programs established in accordance with the terms of an endowment
gift. It also provides a hedge against
downturns in the economy; fluctuations
in the political climate in our community,
region, state, nation and world; variations
in the number of alumni and friends supporting the school's annual appeal; and
other changes in the academic environment. Today's students and faculty benefit from the
endowment gifts of previous generations. Tomorrow's
school is being created by today's endowment gifts.
The market value of the school's combined
endowment assets was right at $145 million as of
June 30, 2000. This represents an increase of nearly
10 percent since 1998, when the school's endowment
was $132,161,604.
During the "Campaign fo r UB: Generation to
Generation," I trust the endowment will continue to
show such significant increases. This will require many
new endowment gifts designated for the school, in addition to the ongoing wise management of the funds
already in the care of the State University of ew York
and the UB Foundation.
" D EVELOP M EsT"

Co s T I ~UEo o s

Autumn

PAGE 30

2000

l alflll H y sici11

29

�--------

D

-

E

-

V

E

"T'Y J

~

L

0

P

M

E

N

T

E

W

CLIN ICAL PREVENTAT I VE MEDICI NE FELLOWSHIp

D flit

" 'G PAGE, we list the School of

Medicine and Biomedical Sciences' endowments held by both the UB
Foundation and the state. Those in bold print received one or more
gifts during the past fiscal year ( through 6/ 30/00 ) ; an asterisk*
indicates a new endowment, established during the same time frame.
Those of us who learn , teach a nd conduct research in this unique
institution extend our thanks to all alumni and friends who made
endowment gifts or finalized endowment agreements in the past year.
If you would like information about 1n1t1ating a named
endowed fund, or if you have any questions regarding the school's combin ed endowment, please
Linda ( Lyn) ]. Corder, associate dean and
contact me.
director of development, can be reached,
toll-free, at 1-877-826-3246, or via e-mail
at Ijcorder@buffalo.edu.

ALMON

H.

COOKE

CHOLARSHIP

PATRICK BRYANT COSTELLO MEMOR I AL
CTG ONCOLOGY FUND
) AMES

H.

EDWARD

CUMM I NGS SCHOLARSH I P

L.

CuRV ISH M.D . AwARD

" MA X D OU BRAVA }R. S C HOLARSHIP FUND
THE ELIZABETH MED ICAL AWARD
DR. RoBERT M. ELLIOT ScHOLARSHIP
ELEANOR FITZGERALD FAIRBA I RN ScHOLARSHIP
FAMILY MED ICINE ENDOWMENT
FEYLER FUND FOR R ESEARCH IN
HoDGK I N's D i sEASE
DR. GRANT

L.

T.

FISHER FUND

WALTER Fix M.D . '42, '43 E

DOWED

SCHOLARSHIP
EDwARD FoGAN MEMOR I AL PRIZE
FORD FOUNDAT ION FOR MEDICAL EDUCAT ION
THOMAS FRAWLEY M.D . RESIDENCY RESEARCH

H.W. ABRAHMMER MEMOR IAL SCHOLARSHIP

THOMAS R. BEAM, ) R. MEMORIAL

S I DNEY ADDLEMAN MEMORIAL

DR. RoBERT BENNINGER FuND I N ORTHOPOED ICs

" F uN D FOR CE LEBRATI NG PHI LANTHROPY

DR. GEORGE) . ALKER FUND FOR

RoBERT BERKSON MEMORIAL AwARD IN THE

MARCOS GALLEGO M.D. CLINICAL

NEURORADIOLOGY

ART OF MEDIC I NE

THEODORE &amp; BESSIE G. ALPERT SCHOOL OF
MED IC I NE SCHOLARS HI P

MusEuM oF NEUROANATOMY FuND
LOU IS). BEYER SCHOLARSH I P

ExcELLENCE FuND
RONALD GARVEY M.D. STUDENT
L IFE ENRICHMENT FUND

ALPHA OMEGA ALPHA ENDOWMENT

PAULK. B I RTCH M.D. FUND

)AMES GIBSON ANATOMICAL PR IZE

ALP H A OMEGA ALPHA L I BRARY FUND

" DR. W I LLARD AN D } EAN BOA RDMA N

WALTERS. GOODALE

AMER ICAN ACADEMY OF FAMILY PHYS IC I ANS
PRESIDENT's AwARD

EN DOWM ENT

BOOKE FUND

ANATOMICAL SCIENCES

OF PEDIATR ICS
GEORGE GORHAM FUND
DR. BERNHARDT

ANESTHES IOLOGY DEPARTMENT ENDOWMENT

ANNE AND H AROLD BRODY LECTURE FUND
CLAYTON MILO BROWN MEMOR IAL

L.

GEORGE

B . BADGERO MEDICAL SCHOOL FUND

VIRGIN I A BARNES ENDOWMENT

. BuRWELL FuND

DR. WINFIELD

L.

VINCENT CAPRARO LECTURESHIP FUND

PH A RM ACOLOG Y

-

DR. CHARLES A. BAUDA AWARD IN

CLAS

OF I945

DR. CHARLES CARY MEMOR IAL

FAM I LY MED ICINE

DR. AND MRS. jOSEPH A. CHAZAN MEDICAL
ScHOLARSHIP

l uff lll n y sicill

BUTSCH MEMORIAL LECTURE

IN CLIN ICAL SURGERY

* DR. ALL EN BARNET T F ELLO W S H I P I N

Autumn

2000

A . CoNGER GooDYEAR PRoFESSORSHIP

)AMES H. BORRELL UROLOGY FUND

BACCELLI MEDICAL CLUB AWARD

WALTER BARNES MEMOR IAL SCHOLARSHIP

CHOLARSHIP

I RENE P I NNEY GooDWIN ScHOLARSH I P

DR. SoLOMON G. BooKE AND RosE YASGUR

BERNHOFT- DESANTIS LIBRARY FUND FOR

30

FELLOWSHIP FUND

. AND DR. SoPHIE B. GoTTLIEB

AWARD
* AD E LE M. G o TTSC HALK S c H O LARS HIP F uND
CARL GRA GER M.D. ENDOWMENT
DR. PASQUALE A. GRECO LOAN FUND
THE GLEN

E.

GRE HAM M.D. VISITING

PROFESSORSHIP
DR. THOMAS). AND BARBARA
ScHOLARSHIP &amp; AwARD

L.

GuTTuso

�GYNECOLOGY-OBSTETRICS DEPARTMENT
ENDOWMENT
)EAN SARAH HAHL MEMORIAL
EuGENE). HANAVAN ScHOLARSHIP
FLORENCE M. &amp; SHERMAN R . HANSON FUND
FOR MEDICAL EDUCATION
DEVJLLO V . HARRINGTON LECTURESHIP
THE HEKIMIAN FUND

MICROBIOLOGY MEMORIAL FUND

ELIZABETH ROSNER FUND

DR . DAVID KIMBALL MILLER AWARD

IRA G. Ross CHAIR oF MEDICAL INFORMATics

EuGENE R. MINDELL M.D. CHAIR IN

DR . SHELDON ROTH FLEISCH MEMORIAL FUND
HAROLD

ORTHOPAEDIC SURGERY
G. NORRIS MINER M.D . MEMORIAL AWARD
PHILIP D. MoREY ScHOLARSHIP

PHILIPP . SANG MEMORIAL FUND

RICHARD

SARKARIA FAMILY ENDOWED CHAIR IN

AGEL M.D . ANESTHESIOLOGY

RESEARCH

HEWLETT FAMILY ENRICHMENT FUND
FOR PSYCHIATRY

DR. ANGES

RESOURCES FUND

DIAGNOSTIC MEDICINE FUND

s. NAPLES MEMORIAL SCHOLARSHIP

THE DR. S. ROBERT

CHARLES GORDON HEYD MEDICAL

ARINS MEMORIAL AWARD

ATIO ' AL MEDICAL AssociATION,

SCHOLARSHIP FUND

NAUGHTON AWARD ENDOWMENT

DR. ERWIN NETER MEMORIAL

* DR. S u K K1 HoN G MEMO RI AL FuN D

ANTOINETTE AND LOUIS H.

ABRAHAM M. HoROWITZ FuND

NEUROLOGY DEPARTMENT ENDOWMENT

LUCIEN HowE PRIZE FUND

DR . BENJAMIN E. &amp; LILA 0BLETZ PR IZE FUND

R. R. HUMPHREY &amp; STUART
Nu SIGMA

C.

L.

VAUGHAN

u ALUMNI ScHOLARSHIP

. )OHNSTON SCHOLARSHIP

SUMNER )ONES LIBRARY FUND

EUBECK FUND

IN ORTHOPAEDIC SuRGERY
DR. ELIZABETH P. OLMSTED FUND I

SCHOLARSHIP OF THE PROGRESSIVE MEDICAL
CLUB oF BuFFALO
SCHOOL OF MEDICINE AND BIOMEDICAL SCIENCES

HARRY E. AND LORETTA A . )ORDON FUND

VICTOR A . PANARO MEDICAL SCHOOL FUND

H. CALVIN KERCHEVAL MEMORIAL FuND

F. CARTER PANNIL )R., M . D. AWARD

DEAN STOCKTON KIMBALL MEMORIAL
ScHOLARSHIP

UNRESTRICTED ENDOWMENT FUND
LILLIE S. SEEL ScHOLARSHIP
IRENE SHEEHAN FuND
DEWITT HALSEY SHERMAN AND
)ESSICA ANTHONY SHERMAN FuND
DR . L01sA . AND RUTH SIEGEL TEACHER's AWARD
S . MoucHLY SMALL M.D. AwARD IN

BIOCHEMISTRY
josEPHINE HoYER ORTON TRUST FuND

PSYCHIATRY
S. MOUCHLY SMALL M.D. EDUCATION
CENTER FUND
IRVINE AND ROSEMARY SMITH CHAIR IN

ENDOWMENT
STEPHEN). PAOLINI M . D. MEMORIAL FUND

APLES SARNO SC H OLA RSHIP F UND

ScHAFER FuND IN CARDIOVASCULAR DISEASES

EPHROLOGY RESEARCH ENDOWMENT

RALPH HocHSTETTER MEDICAL RESEARCH FuND

)AMES

* D R. MA RI A

BuFFALo CHAPTER ScHOLARSHIP FuND

DR. FRANK WHITEHALL HINKEL

s. SANES AND THELMA SANES MEDICAL

SCHOLARSHIP

NEUROLOGY FUND
DR. IRVING M. SNOW FUND

DEAN STOCKTON KIMBALL MEMORIAL AWARD

PARKINSON RESEARCH FuND

MARY RosENBLUM SoMIT ScHOLARSHIP FuND

DR. )AMES E. KING POSTGRADUATE FUND

)OHN PAROSKI MEMORIAL FUND

MORRIS AND SADIE STEIN NEUROANATOMY PRIZE

MoRRIS LAMER AND DR. ROBERT BERNOT
SCHOLARSHIP
DR. CHARLES ALFRED LEE ScHOLARSHIP
DR. GARRA K. LESTER STUDENT LOAN

RoBERT]. PATTERSON RESIDENT AwARD

* j o H N AN D ) ANET SuNG Sc H OLA RSHIP FuND

DR. MARK PETTRINO MEMORIAL FUND

]oH

PHI CHI MEDICAL FRATERNITY

TREVETT SCHOLARSHIP

SCHOLARSHIP FUND

H. TALBOTT VISITING ScHOLARSHIP FuND

* K o R NELL

L.

TE RPLAN M .D . L ECTURE FuND

PRIMARY CARE ACHIEVEMENT FUND

RICHARD E. \VAHLE RESEARCH FUND

THE LIEBERMAN AWARD

PROGRESSIVE MEDICAL CLUB OF BUFFALO FUND

MILDRED SLOSBERG WEINBERG ENDOWMENT

HA

PsYCHIATRY DEPARTMENT ENDOWMENT FuND

E.). WEISENHEIMER OPHTHALMOLOGY AWARD

LUPUS SCHOLARSHIP FUND

DR. HERMAN RAHN MEMORIAL LECTURE

DR. MARK WELCH AND BEULAH M . WELCH

WILLIAM E. MABIE D . D .S. AND

ALBERT AND ELIZABETH REKATE CHAIR IN

LLOYD LEVE FUND

s LOWENSTEIN AWARD

GRACES. MABIE Fu

D

DR. WILLIAM H. MANSPERGER FuND
CLARA MARCH MEDICAL ScHOLARSHIP

CARDIOVASCULAR DISEASE
ALBERT

C.

REKATE REHABILITATION MEDICINE

LIBRARY FUND

MEDICAL ALUMNI ENDOWED ScHOLARSHIP

DONALD RENNIE PRIZE IN PHYSIOLOGY

ANNUAL PARTICIPATING FUND FOR MEDICAL

DouGLAS RIGGs AwARD IN PHARMACOLOGY AND

EDUCATION ENDOWMENT

THERAPEUTICS

ScHOLARSHIP
)AMES PLATT WHITE SOCIETY ENDOWME T
WILLIAMS/BLOOM MEDICAL RESEARCH FUND
DR . MARVIN N . WINER FUND FOR
DERMATOLOGICAL RESEARCH
WITEBSKY FUND FOR IMMUNOLOGY
DR. ERNEST WITEBSKY MEMORIAL FUND

MEDICAL SCHOOL LECTURESHIP FUND

THE RING MEMORIAL FUND

FARNEY R. WuRLJTZER FuND

MEDICAL ScHOOL CLASS oF 1957 ScHOLARSHIP

MEYER H. RIWCHUN PROFESSORSHIP IN

DR . MARK ZALESKI AWARD

MEDICAL SCHOOL CLASS OF 1958 SCHOLARSHIP

OPHTHALMOLOGY FUND

MEDICAL SCHOOL CLASS OF 1963 SCHOLARSHIP

EMILE RODENBERG MEMORIAL AWARD

MEDICAL SCHOOL CLASS OF 1973 SCHOLARSHIP

THOMAS A. RODENBERG AND EMILE DAVIS

MARIAN MELLEN FuND

HERMAN AND RosE ZINKE MEMORIAL
SCHOLARSHIP

RODENBERG SCHOLARSHIP FUND

Autumn

2000

luffal1 Hysici11

31

�Dear Fellow Alumni,
'GI"\ :-.IY YEAR AS PRESIDE:-\T OF THE MEDICAL ALU\1 ' I AssOCIA'I'lO, ' , I am looking at
a well-run, hard-working volunteer organization. Our organization has two major objectives. The first
one is to promote and encourage alumni interest and activity in the School ofMedicine and Biomedical
Sciences. This is done through our Spring Clinical Day and Reunion Weekend, countrywide meetings,
awards dinners, luncheons and various other activities. The second objective is to help the medical
students-from orientation through graduation-to assimilate into our profession, to
grow as doctors and as human beings and to have some fun in the process.
The Medical Alumni Association sponsors events at orientation. Along with the
White Coat Ceremony for the incoming students, we have a Physician-Student Mentoring
Program, which has received excellent feedback. Our Community Physician Program
allows first- and second-year students to meet area doctors and talk about their
specialties. We also organize a senior reception and a Match Day luncheon, and entertain requests from
the student government.
So, what's wrong with the picture? Here's where I start to sound like a guy on public television. Our
organization, like most volunteer groups, relies on support from its constituents. Our school has about
6,000 living graduates, but we only average about 1,500 dues-paying members each year. We need your
help! I would like to issue a challenge (again, just like public television). A lifetime membership in the
Medical Alumni Association costs $750. This is a bargain for younger doctors and a great way for the
"mature" doctors to support our school.
In order to continue to increase all the association's activities each year for our school, its students
and alumni, we need 200 new lifetime members by May 200 I. Anyone who joins the Medical Alumni
Association as a new lifetime member between September 2000 and May 2001 will receive a free copy
of our new University at Buffalo School ofMedicineand Biomedical Scie11ces Alumni Directory, which will
be published in May 2001.
As our pulmonary colleagues would say, "Come on, cough it up!" Please help your school-join the
Medical Alumni Association now!

jOHN

I

....

j.

BODKIN

II,

MD

President, Medical Alumni Association

Pbysici11

A11t1111111

2 000

�CLASSNOTES

1940s

1950s

Eugene J. Hanavan, MD '41 ,

Roland Anthone, MD '50,

an associate clinical professor of orthopaedic
surgery at VB, retired
from practice February
29, 2000 and resides in
Buffalo, Y.

Buffalo, NY, "Did surgery and renal transplantation surgery for 50
years and am now enjoying retirement, although
still doing some parttime work with BGH.
Spend time with my wife
playing tennis and golf."

William E. Maloney, MD '41 ,

writes, "I retired to York
Harbor, ME, after years
of anesthesia practice in
New York. I am married
with three children and
three grandchildren.
My health is not too
good. Broken hip, etc.
Age 82. Anyone still alive
of 194!s?
Edward M. Tracy, MD '43,

writes: ''I'll be 82 soon,
but still practice internal
medicine six days a week
with a group of physicians I formed last year.
I continue to be involved
with students at the
Medical University here
[in South Carolina] and
do the same in China.
Chick (most of you
know her) and I have
been married 57 years
and have 7 children, 17
grandchildren and 2
great grandchildren. I
am in excellent health
and enjoy my dog
and horse."
John G. Allen, MD '46,

writes: "I am looking
forward to my 55th reunion in spring 2001."
E-mail is jallenl391 @aol.

Sidney Anthone, MD '50,

Buffalo, NY, surgery,
"Am currently director
ofU YTS."
Robert E. Bergner, MD '50,

Colden, Y, internal
medicine: "Married 50
years and still happy. We
have five children and
eight grandchildren. I
retired after 43 years in
private practice. Still
playing cello in the Orchard Park Symphony
Orchestra and am singing in the church choir."
Adelmo P. Dunghe, MD '50,

Highland Beach, FL,
family medicine: "!
recently retired from
the U.S. Army; happily
retired since 1989; happily married since 1948."
James C. Dunn, MD '50,

Tucson, AZ, general surgery: "! have been on the
faculty at the University
of Arizona's College of

Representatives of Bernard C. Harris
Publishing Company, Inc., will start
phoning alumni for the verification phase
of our Unirerslty ilf Buffalo School at
MedH:ine and BiomedH:al Sciences
Alumni Direcfoty project.
Much of the information to be verified
on each individual's listing will be going
into the directory; in particular, this
includes current name, academic data,
residence address and II"- number (if
applicable!. The scope of this information
is an indication of the comprehensive
quality of the entire volume. The dlrec·
tory will sort this data by name In the

Medicine since 1978 in
the Department of
Anatomy. I was on the
faculty at SU Y at Buffalo from 1957-1978, in
the Department of
Anatomy," E-mail is
azcacti@acol.com.
Yale Solomon, MD '50,

Brightwaters,
, ophthalmology, recently
authored a book for laymen, titled Overcoming
Macular Degeneration: A
Guide to Seeing Beyond
the Clouds, Avon Books.
E-mail address is
ysolomon@earthlink.net.
James Youker, MD '54, was
elected president of the

alphabetical division, and by class year,
and geographical location in separate

sections of the book. There will also be
a special message from the Alumni
Office as well as photos and information
about the school.
Soon, locating fellow alumni will be
as easy as turning a page in the Univer·
sity ilf Buffalo School at MedH:ine and
BiomedH:al Sciences Alumni Directory.
You may resene your personal copy
when your Harris representative
phones, but don't delay because only
pre-publication orders received at that
tiRM will be guaranteed.

American Board of
Medical Specialties
(ABMS) in March 2000.
In this capacity, he will
work closely with Steve
Scheiber, MD '64, executive vice president of the
American Board of Psychiatry and eurology,
who is active on a number of committees of the
ABMS. E-mail address is
jyouker@mcw.edu
Laurence J. Beahan, MD
'55, Snyder, NY, psychia-

try. "!am chair of the Sierra Club iagara Group
2000 and am publishing a
book titled My Grampa's
Woods: The Adirondacks.
Am on the Public Health
Committee Medical
Society County of Erie."

E-mail address is
larry_beahan@adelphia.net.
Leonard R. Schaer, MD '55,

Alamo, CA. "I am retired." E-mail address is
nanapop@hotcoco.infi.net.
William J. Sullivan, MD ' 55.

writes: "I am practicing
half time at the present as
the medical
director of a
group doing
forensic psychiatry. I have
stopped my
psychoanalysis
and psychotherapy. I hope and expect to continue to practice for a number of
years more."

I

CONTINUED ON PAGE 34

assnotes
Autumn

2000

l uff al1 Physician

33

�~ ---

---

- - - --

-

-

CLASSNOTES

CO NTI NU ED FR O M P AC E 33

the hospital will be
named in their honor.

Barbara YonSchmidt, MD
'55, Oakland, CA, pa-

thology. "I retired
December 31, 1991, after
working 35 years at
Children 's Hospital of
Oakland. "
Jacques Lipson, MD '58,

and his wife, Dawn,
received the john
Whitbeck, MD, Medal
of Philanthropy for the
Year 2000. This was
awarded by the Rochester General Hospital
Foundation. The newly
constructed cancer and
blood disorder center at

1960s
William E. Abramson, MD
'60, writes: "I enjoyed

reading the Buffalo Physician summer 2000 issue. Also enjoyed seeing
30 of my classmatesstill vertical-at our reunion dinner on April
29, 2000. How come the
Class of 1950 got the attendance trophy with 24
attendees, when we had
31 ?" {Editor's note: In re-

sponse to Dr. Abramson's
question, the Medical
Alumni Association Office

'11
who is

chai~

explains that the attendallce trophy is determined by proportional
represe11tatio11; i.e., the
percentage of surviving
members who attended. ]

of the Department of Oral Diagnostic
Sciences in the School of Dental

Naomi leiter, MD '60, New

York, Y, adult and
child psychiatry. " I live
near Lincoln Center and
would love if my classmates visited with me.
My eldest son is a
"professor" at the ew
School. My youngest son
is starting his own theater company called Imbalance as director and
artistic director. " E-mail
is nl7012 @aol.com.
Paullessler, MD '63, has

been named director
of Pain Management
at University of
Southern California's
orris Comprehensive
Cancer Institute in Los
Angeles, CA.
J. Richard Gunderman, MD
'65, writes: " In 1999, I

published a book,

Raisi11g Your ChildA Love Story, on how
to raise children. "
E-mail address is:
dickgund @aol.com.
louis Trachtman, MD '65,

writes: "Buffalo Physician
is always enjoyable, but I
was especially moved by
Dr. Bean's article in the
spring issue. It reminded
me of the teaching methods of our professor of
pathology at UB, Dr.
Samuel Sanes, who
taught the natural course

34

IU II I II

rh JS I CI ID

A11111mll

2 000

of diseases
from the
patient's
perspective. P. S.,
I recently
.....:t.:....,.L.:...;;;;....J
had two
articles
published in our state
medical society's journal, highlighting public
health." E-mail:
trachman@dhh.sta te.la. us.
Andre D. lascari, MD '60,

Poestemkill, NY, pediatric hematology/oncology.
"I retired in April 1999.
William G. Wolff, MD '69, is

president of the New
York State Radiological
Society; councilor of the
American College of Radiology; Advisory Committee on Radiological
Health to New York State
Department of Health.
He is chair of the Department of Radiology at
The ew York Hospital
Medical Center of
Queens, Flushing Hospital Medical Center,
Coler-Goldwater Memorial Hospital; clinical
associate professor of the
Weill Medical College of
Cornell University; and
senior member of the
American Institute of
Ultrasound in Medicine
and member of the
Executive Committee
of ew York Medical
Imaging.

1970s
John E. Knipp, MD '72, has

been elected chief of medi-

cine at St. Luke's Hospital
m ewburgh, NY.
Eric J. Russell, MD '74,

Dr. Russell 's corrected
E-mail address is
e-russell@nwu.edu.
Nancy A. Cunningham, PhD
'78 and '80, has been a p-

pointed medical library
administrator in the Department of Educational
Affairs at Roswell Park
Cancer Center (RPCI ).
In this role, she will
supervise and direct
personnel, fiscal and
budgetary planning and
operations of the Dr.
Edwin A. Mirand
Library and
implement
and coordinate
library marketing and
outreach
activities.
Peter Condro Jr. MD '79.

Dr. Condro's corrected
E-mail address is
crrtfo ra rf@cs. com.

1980s
Edward J. Rockwood, MD
'80, writes: "My wife,

joann Agnello
Rockwood, died of
breast cancer on july 29,
2000. She worked in the
Medical Education Office at Millard Fillmore
Hospital from 1977 to
1983, first with Dr.
Harry Alvis and then
with Dr. Luther
Musselman. We have
four daughters: Tiffany,
13, Delena, 12, Ashley,

�In Memoriam
school, Ihrig, who retired

attended SUNY at Buffalo,

editors of national and

professor at Hershey

in 1991, was on the staffs

where he earned his un-

local news media. He is

Medical Center from

36 years at 71 North

of Buffalo General,

dergraduate and medical

survived by his wife of

1972-1995. Yahn was

Street in Buffalo, NY, died

Children's and the former

degrees. Klein co-founded

over 30 years, the former

a native of Olean, NY

July 7, 2000, at age 71. A

Lafayette General hospi-

Williamsville Obstetrics

Lois ("Cookie") Joseph

and a graduate of St.

native of Chicago, Ihrig

tals for many years, as

and Gynecology, where he

Cominsky, three stepchil·

Bonaventure University.

graduated from the then-

well as the Erie County

practiced for over 30

dren and three children

He was a Navy veteran,

University of Buffalo in

Medical Center. Survivors

years. In addition, he was

from his previous mar-

a fellow of the Ameri·

1953, with honors. Follow-

include his wife, the

a clinical assistant pro-

riage to Shirley Gerring.

ing medical school, he

former Jeanette S. Latona;

fessor of OB/GYN at UB

completed his internship

two sons, four daughters,

and an active member of

Arthur E. Yahn Ill, MD

at Bexar County Hospital

and a brother.

the American Medical As-

'65, died at his orne n

of Anesthesiology and

sociation and the Ameri·

Har• sburg, PA, on May

the National Board of

John J. Ihrig, MD '57,

ho

practiced dermatology for

in San Antonio, TX, and

can College of Anesthesiologists, a Diplomate
of the American Board

served three years in the

Morton Paul Klein, MD

can College of Obstetrics

15,2000,afteralong

Medical Examiners.

Air Force, where he rose to

'62, died April 5. 2000

and Gynecology. An avid

battle with spindle cell

Surviving are his wife,

the rank of captain. He

in Delray Beach, FL, of

recreational bicyclist,

fibro sarcoma. He was

Mary Ann Krastell

then returned to Buffalo

complications following a

world and RV traveler and

60. Yahn had been on

Yahn; three daughters,

and began his practice in

bicycle accident. He was

gourmand, Klein was also

staff at Harrisburg

three sons, his mother,

1965 after completing his

68. A native of Union City,

an active supporter of Jew-

Hospital since 1971 and

two sisters, and
a brother.

residency in dermatology

NY, Klein served in the

ish community activities in

director of anesthesiology

at UB. In addition to serv-

U. S. Navy as a medical

Western New York and a

services there from

ing as a volunteer faculty

corpsman during the

frequently published con-

1975-1977. He was also

member at UB's medical

Korean War. He then

tributor of letters to the

an assistant clinical

10, and Amanda, 5. I am
a staff ophthalmologist
at the Cleveland Clinic
Foundation, subspecializing in glaucoma. »
E-mail address is:
edwardrockwood@aolcom.
Steven R. Goodman, MD '84,

practices physical and
rehabilitation medicine
in Federal Way, WA. He
is a clinical associate
professor at the University of Washington's
Multidisciplinary Pain
Center, where he teaches
intramuscular stimulation for the treatment of
neuropathic-myofascial
pain syndromes.

E-mail address is
srgood@home.com.
Francis Whalen, MD 'B7,

writes: "I have just completed an internal medicine residency and will
start a pulmonary critical care fellowship in
July at Pittsburgh."
E-mail address is
fwhalen@adelphia .net.
Thomas E. Kowalski. MD
'BB, has been named

medical director of gastrointestinal endoscopy
in the Division of Gastroenterology and Hepatology, Department of
Medicine, at Thomas

Jefferson University
Hospital in Philadelphia.
He is
also associate
professor of
medicine at
Jefferson
Medical College of Thomas Jefferson University.

1990s
Rohit Bakshi, MD '91, has

been awarded a threeyear, $300,000 grant
from the JH-Nl DS to
study MRI findings in
multiple sclerosis. The

work will be carried out
in the Department of
eurology at Kaleida
Health System's Buffalo
General Hospital, where
Dr. Bakshi is a neuroimager and MS specialist. E-mail address is
rbakshi@buffalo.edu.
Mary (Cappuccino)
Bonafede and Joseph P.
Bonafede, MDs '91. write:

"We are happy to announce the arrival of our
third child, Andrew Joseph, on February 1,
2000. Andrew joins his
big brother, Sam, age 4,
and his sister, Ella, age 3.
Joe and 1 are both enjoy-

A u t u mn

20 00

CD

ing private practice
(otolaryngology and
pedia tries) on the eastern shores of Long
Island. E-mail address is
Mbon.465050@aol.com."
Philomena Mufalli Behar,
MD '92, writes: "My hus-

band, Jerry, and I would
like to announce the
birth of our daughter,
Julia Fay, on June 25,
2000. She weighed five
pounds, 12 ounces, and
was 18 inches long."
E-mail address is:
pmbehar@aol.com.

C ON T IN U E D ON P AG E 36

1 1 If al•

n ysic ian

35

�CLASS

I

CON TIN UED

FR O \~ ~

35

Warren Scherer, MD/PhD
'92, writes: " I served as

the ophthalmic surgeon
for a medical mission to
El Salvador in August
2000. I am currently in
private practice in ew
Port Richey, FL." E- mail
address is warren
scherer@hotmail.com.

E-mai

NOTES

Michael Aronica MD '93,

writes: "I am proud to
announce the birth of
our third child, Marykate. Meghan and
Madeline just love their
little sister. Mary and I
are doing well in Buffalo,
NY. I am enjoying my
job with the Division of
Internal Medicine and
Pediatrics at the U
Buffalo School of Medicine. My clini-

cal duties are based at
the Elmwood Health
Center and Children's
Hospital of Buffalo."
Alissa Shulman, MD '93,

writes: "I am pleased to
announce I have recently
joined a wonderful and
busy plastic surgery
practice- Plastic urgery, P. C.- in South
Bend, IN. An additional
note: I have continued
with my artistic endeavors, both personally and
professionally. Life is
good!" E-mail address is:
doctoral issa@aol.com.

Donna (Sinensky) Ferrero,
MD '94, writes: "I recently

joined a large multispecialty private practice
in orth Andover,
MA- ew England
eurological Associates,
P. C. I am practicing
physiatry. I am also
happy to announce that
my husband and I are
expecting our first child
in March 2001."
Babak Parwar, MD '96, and
Bobbie Parwar, MD '97.

Babak writes: "I am in
my fourth year of head
and neck surgery at
UCLA Medical Center.

My wife, Bobbie, is in
her second year of ophthalmology at the Jules
Stein Eye Institute in
Los Angeles."
Kristin Larsen, PhD '97,

writes: "It's been a good
year for me. I got married in September 1999
and was recently promoted to junior faculty
in the Department of
eurology at Columbia
University. My research
angle is alternative
therapies and preventions for Parkinson's
disease." E-mail address
is kell4@columbia.edu.

A plan for livllg.
Hospice really is a plan for living ...
one that we can make together.
With treatment options from you,
plus emotional support, symptom

I plan to keep going.

management and in-home care from
Hospice, we can help your patients
make the most of their time with
family and friends. Call 686-8077.
T H E

C E;&gt;.;TER

F O R

H1)SPICE&amp;
PALLIATIVE CARE
www.lzospicebtiffo lo. com

36

l•flale Pbysiciaa

A utu m"

2000

�- Based on F/Mst-1 Data

dnJl

ffTheywere
sergeantsand cheerleaders:'
- Fronk Stelarski, stroke rehab patient Harris Hill H.C.F.

Why do our patients have better rehab resuh:s compared to the national average? Maybe

~·s

our staff

''They knew exactly how far to push me,'' says Frank Stelarski. ''But they also encouraged me every lfttle
step of the way. When you've been through what I have, that really means a
lot.'' To leam more about the nationally recognized McGuire

THE

Rehabil~tion ~~ry}Jfl.I(9!{

Centers, call 1-888-POSTACUTE or vis~ www.mcguire-group.com.

Recognized for excellence in quality· care.

CEN1E~

tf*****"

AUTUMN VIEW • GARDEN GATE • HARRIS HILL • NORTH GATE

�p H

A R M A

c

0

p

0

E I

A

GB's HISTORY
OF MED!Clr-iE
COLLECTIO:-i PRF.SE . . TS
PHARMACOPOEIA

Digitally reproduced
prints from a pharma copoeia by Otto Karl
Berg (1815-1866) are on
display

this

fall

in

University at Buffalo's
Health Sciences Library
(HSL), South Campus.
The botanical show
was developed by the
HSL and the university's
iMedia staff and is the
first

in

a

series

of

"Art in the Library"
exhibits intended to
promote the History of
Medicine

Collection

through the display and
sale of reproductions of
selected works.
Fred Kwiecien and
Don Trainor of iMedia
prepared

the

prints

from the original art in
the Berg volume , published in Leipzig in
1863. Pictu red is Iris
Florentina.

RP 00 02 01

�</text>
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I

c

I

A

N

�lullala P~ysicial

ASSOC IA TE V I CE P RES I DENT FO R
lJ ' I \ ERSITY SER\ I CES

Dr. Carole Smith Petro

Dear Alumni and Friends,

D I R E CTOR Of PERIODICALS

Su e Wu etcl1er
EDITOR

S t ephanie A. Unge r

B

we will no doubt be in the

grips of wi nter, which is supposed to be a bit more bracing here in Buffalo than in recent
years.

,\RT DIRECTORIDESIG,;ER

A lan]. Kegler

evertheless, we do look forward to our predictable changes of seasons and hope
CONTR I BUTING \\ RITFR

that all of you have had a pleasant holiday break from the routine.
The capital campaign "Generation to Generation" kickoff occurred on October 20,

Lois Baker
COORD I ~ATOR

2000, an event coinciding with UB Homecoming Weekend and the convening of our

PRODUCT I ON

Dean's Advisory Council. Our own medical school "Family Weekend" took place over the

Cy nthia T odd - Fli ck

two days that followed. The campaign kickoff was capped by a reception in the Center for
the Arts and a marvelous presentation by the American Ballet Theater Company,

111

residence at UB during October.
Based on progress to date (during the "quiet phase" of the campaign),

ST~TE lJ'dVERSITY OF;\£"

'I ORK AT BurrALO ScHooL
0 F ~~ E D I C I N E A N D
BIOMED I C·\L SC I ENCES

Dr. j ohn W rig ht , Dean

the School of Medicine and Biomedical Sciences' campaign goal has been
adjusted upward to $50 million dollars. With Skip Garvey, MD '53, as our
campaign committee leader, we not only expect to achieve that goal over
the next three years but indeed to surpass it. Endowment means so much
to a school such as ours, a fact to which I can personally attest as we manage our way through what have become very challenging times. A healthy
endowment will enable many good things for the school, not the least of
which will be the ability to attract the very finest student applicants and to provide them
with the very best medical education experience. All this would benefit from a significant

E.DITOR I AL BOARD

Dr.
Dr.
Dr.
Dr.
Dr.
Dr.
Dr.
Dr.
D r.
Dr.

Bertram Portin , Chair
Mart in Brech er
Har old Brody
Linda]. C orde r
Alan]. Drinnan
]am es Kan ski
Eli za beth Olm sted
S teph en Sp a ulding
Bradley T. T rua x
Franklin Ze plowitz

increment in student scholarship availability, which has become so important in the recruitment of excellent students and, through endowed professorships, enabling us to recruit
the very best faculty with whom our students can interact, learn and become inspired.
As we head into completion of the fall semester, significant progress has been made on
developing the new curriculum that we intend to implement in the fall of 2001. Dr. Reid
Heffner (assistant dean for curriculum and chair of pathology) is coordinating this effort
with the help of a team of dedicated, experienced teaching faculty. The intent is to better
integrate course material into a more clinically focused formal in which repetition is intentional rather than accidental, and relevance to basic overarching biologic concepts and
clinical application becomes more transparent. The curriculum will also provide more
lecture-free time so students can consolidate information on their own and access modern
instructional technology; for example, through the use of the computer lab. Since there will
be more small-group teaching in the new formal, we arc already planning significant ex-

TEACHING HOSPITALS

Er ie Co un ty Med ica l Ce nt er
Roswell Pa rk Ca n ca l11 stit11 t&lt;'
\'e te ra 11 s Affai rs W es te ru
New Yo rk H ealt h ca re Syste m
K-\11/1)-\ H fo\1 Ill :

T h e B uffa lo Ge 11 era l H osp ital
T h e Child re 11 's H osp ita l of Buffalo
.\ I ill ard Fi llm o re Ga tes H ospilll l . I
.\ I ill ard Fillm ore S ubu rba u Hosp tttl
H I-\1111 Snrt.u:
Me rcy H ea/t/1 Sys t em
Sisters of C h ari ty H ospiw l
N tagara Fa lls M e m oria l
Me d ica l Ce ut er

C-\riiOIH

® THE STATE UNIYEISITT Of NEW Ylll IT lUFf ILl

pansion of that type of learning space to be ready in time for the implementation date.
Although curriculum change is in fact a constant for most schools, this project promises
to be more dramatic than any change effected in recent memory. It is unlikely to be perfect
at implementation, but we think it will be a significant improvement for our students,
nonetheless. Further improvements will be accomplished as experience with the new
curriculum evolves. Our goal is to maintain the UB tradition of graduating physicians
capable of meeting the challenges of the continually evolving world of medicine.

.JOliN

R. WRIGHT. MD

Dean, School of Medici11e and Biomedical Sciences

Letters to the Editor
liu(falo l'hp1wm " pubh,hed qu.trterh
h' the C nivcr&gt;it\ at Bufl;11o School of
,\kdicinc .md BiomcdiLal Science!-. .111d
the Offkc of &lt;:ommunic.ltions.
1 etters to the h.litor arc wckomc
and can be sent CIO Buflalo Phplcimz.

330 t rofh II all, L'ni,~;,i1y al Buff;,lo,
Buffalo,!'\\ 14260; or ,·ia c·maillo
hp-notcs •' butf.tlo.cdu.
The 'laff re,crvc' the righl to edil ,,II
... ubmlssiom, for length and daritr .

�VOLUME

35,

Features

2

Warsaw after the War
Morris Unher, MD '43,
looks back on his year
as a medical officer in
post-war Poland
PHOTOGRAPHY BY DR. MORRIS UNHER

8

Writing Code
Medical students draft
first -ever code of
conduct for school
BY DAVID FLINT.

CLASS OF 2003

PHOTOGRAPHY BY FRANK MILLER

Emergency medicine resident Ann Marsh competed on the U.S. Fencing Team in the 2000 Summer
Olympic Games inSydney. The story of this remarkable physician·athlete begins on page 26.

COVER

PHOTO

BY

DR.

MORRIS

UNHER

Medical School
34 Mark your

14 UB medical
st udents named
HHM I- IH
research
scholars

16 Frederick
Sachs to lead
international
research project

20 Honors Brunch
Awardees

named 2000
Distinguished
Medical
Alumnus

26 Philip Wels
selected for
1936 u.s.
Olympic
fencing
team

campaign,
"Generation to
Generation"

31 Lung function
associated with
longevity

33 Blood vessels
reflect future
health

calendars for
April 27-29,
2000, for Spring
Clinical Day
and Reunion
Weekend
Messages from
Reunion Chairs

39

your UB
classmates and
other alumni
In Memoriam
Drs. Henry
Morelewicz,
Eugene Farber,
Arthur Schaefer

AP9 2 7

.-

J

. .J

���ter the
nexpectedly, however, the dull routine came to an end when I received orders to report to the Surgeon General's Office
in Washington,DC, followed by assignment as medical officer at the U.S. Embassy in Warsaw. Avivid memory 1have of my
brief stay in Washington involves avisit from my parents, both native·born Russian, and asomewhat embarrassing
moment when my mother asked my superior officer why it had to be hers on who was selected for this assignment.
From Washington, I traveled to Camp Kilmer, ew Jersey,
then on to the port of embarkation, where I boarded the USS
Claymont, a "victory class" transport ship. During the boarding,
I learned that I was to serve as transport surgeon for the 900
troops already on board. Fortunately, our voyage was uneventful.
Our ship arrived at LeHavre, France, and from there I traveled
to Paris where I spent a sleepless 36 hours enjoying the sights
and sounds of that beautiful city, which was spared the destruction I was soon to encounter farther east.
When it was time to leave Paris I boarded a troop train that
carried me to Berlin. Along the way, I began to catch glimpses of
burned-out villages. The Berlin I arrived in was a city divided
between U.S., French and Russian sectors, all of which were in the
throes of reconstruction following nearly complete demolition.
From Berlin, I made the 400-mile flight to Warsaw on board a
C-47 U.S. army transport plane that departed from Templehof
Airport, a busy place with military planes taking off and arriving
from many destinations.
On our approach to the Warsaw Airport, I saw Russian planes
sitting on the field amidst bombed-out buildings and potholed
runways. When we landed we were met by a U.S. military attache's
car and taken directly to the Hotel Polonia-war scarred, but still
standing-and home to the U.S. Embassy while the destroyed
embassy building was being reconstructed. The hotel was situated
on Aleya )erozolimskie (the "Times Square" of Warsaw), across
from tl1e railway station, which had been reduced to a pile of rubble.
Arthur Bliss Lane was the U.S. ambassador at the time, and he
and his wife and many of the embassy staff lived in the Polonia.
Upon my arrival I received a very warm and friendly greeting.
Soon I settled into my routine, providing medical care for employees of our embassy-American and Poles-as well as for
employees of the British and Italian embassies.

Rapid Immersion in "The Polish Problem"
Medical facilities at my disposal were primitive. In the hotel, a oneroom dispensary had been established and stocked with medical
supplies and equipment from the army medical depot in Berlin and
luffale Physician

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with occasional acquisitions from relief agencies in Warsaw.
Dr. Fraczek Litwin, the Minister of Health, graciously placed the
facilities of the Lecznica Ministertwo Zdrowia at our disposal and,
in my year's tour of duty, scarcely a day passed without at least one
staff member occupying a hospital bed there. Throughout my stay,
I had neither a clerical nor medical assistant and, consequently, it
was difficult to maintain adequate records. In all, it would be fair to
state that my services as medical officer were utilized to capacity.
In the course of performing my duties, I had the privilege of
traveling extensively in Warsaw and throughout Poland, visiting many health installations, meeting members of the medical
profession and observing the patterns of medical education and
practice. Friendships with medical students, practicing physicians and health officials offered me much
insight into the "Polish problem" as it was
I will never
referred to then.
By the time I arrived in Warsaw, more
than 500,000 Poles had drifted back to the
city's ruins to live in what was left of cellars
and crumbling attics. I remember observing
how, in a burst of ambitious activity, the
provisional government had posted one
gutted building as the Ministry of Agriculture and another, as the Ministry of
Health, and so on. Everywhere the individual and collective will to live and rebuild
was strong, but the tasks seemed hopelessly
overwhelming in scale.
Despite the inevitable manpower shortage incidental to the war and enslavement,
Poland was consigning an inordinately large
proportion of her remaining men to serve in
the armed forces that were being rapidly rebuilt. So, while platoons of singing troops
marched through the streets and armed militia patrolled the ruins, old women and young
students picked at the rubble.

forget a young
medical student
telling me the
harrowing tale
of how, during
the war, he took
his third-year
medical examinations by
candlelight in
an abandoned
farmhouse while
his fellow students guarded
the doors and
lonely road.

�Warsaw'sdecimated railroad station, situated in the city's"Times Square," as seen from the rooftop of the Hotel Polonia.

Physician Population and Hospitals Decimated
Among the 10 million people who perished during the German
occupation of Poland, 7,000 were doctors, or one-half ofPoland's
physician population at the time. In addition, the country lost its
most able administrators, educators and public health authorities. As a result of this grievous situation, it was a heroic, but
unqualified group that assembled in the Ministry of Health's
headquarters in 1945 to begin the Herculean task of rebuilding the
country's health-care system. Although he held the position of
minister of health, Dr. Litwin, an internist by training, had little
formal public health experience. However, he possessed inexhaustible energy and a humanitarian political philosophy. In less
than a year, this remarkable man reorganized the public health
program in his country, efficiently integrated United Nations
Relief Administration (U RA) and Red Cross aid and gave the
harassed Polish people respite from the fear of epidemic diseases.
In Warsaw, his ministry began the great task of rebuilding the
Polish Medical Library; his laboratories began producing vaccines and serums; and his tuberculosis sanitarium began receiving patients. At the same time, Polish peasants once again began
benefiting from care provided by their local public health officers.

Years later, I learned
that Dr. Litwin was purged in the "communist victory" of January 1947.
Fearing the rise of
epidemics-which fortunately never came-authorities hastily
restored water purification and sewage disposal plants. Concurrently, immunization against typhoid fever was made compulsory as a prerequisite to obtaining food ration cards.
Without dispute, Poland's worst enemies had by then become
tuberculosis, venereal disease, malnutrition and infant mortality,
which were overwhelming the resources and ingenuity of the
country's health authorities. By the time my tour of duty ended,
1,000 new cases of pulmonary tuberculosis were being reported
each week.
Compounding the despair was the fact that Polish hospital
staffs had been disintegrated, medical equipment looted and
buildings destroyed. Fortunately, although there was a shortage
of hospital beds immediately after the war, by the time I arrived,
the recovery of hospital facilities was well under way and
continued at a steady pace while I was working in the country.
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Polish Medical Education, aSurvival Story

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The buildings that housed the University of Warsaw's undergraduate and medical schools were not spared in the destruction
ofWarsaw. A far more irreparable loss, however, was the teaching
staff, which was annihilated by German violence. In effect, the war
brought to an end the education of doctors of medicine by official decree; however, I
learned that surreptitious education continued in the guise of
"schools of sanitation."
I will never forget a
young medical student
telling me the harrowing tale of how, during
the war, he took his
third-year medical examinations by candlelight in an abandoned
farmhouse while his
fellow students guarded the doors and lonely
road. After the war,
despite the fact there
were no books and
instruments, classes
continued to be held.
In 1946, large classesthe majority of which
were made up of
women-were meeting
in scattered clinics
throughout the city.
Strenuous efforts
were being made to reorient the Polish clinical methods away from
the German model and
toward the AngloAmerican model, and
the new Ministry of
Health Library, which
was being generously
supported with U. S.
contributions, was beginning to be a potent
served as an associate clinical professor of
force in Poland's medical education. To this
day, I feel the survival
of Polish medical education must be regarded as a minor miracle.

View of Hotel Polonia, home to the U.S. Embassy staff and Dr. Unher while in Warsaw.

Professional Integrity amid Crime and Politics
In looking back on my experiences in Warsaw, I cannot conceal
my unbounded admiration for the Polish physicians among
whom I lived and with whom I worked. The caliber of the medical
practitioners I met was extremely high and their efforts to bridge
the gap of seven terrible years were commendable.
Those few who were left to serve the country's 22 million
people pooled their meager equipment and books and instinctively sought the urban centers. In the face of the nationalization
program that had been instituted, they turned to group practice,
and collective clinics comprised of 10 to 20 doctors were
becoming common in Warsaw.
All the physicians rallied to the task of rebuilding and restaffing hospitals. Eighteen- to 20-hour days were normal for the
Polish practitioners, who often were required to walk many
miles each day in shell-pocked streets, attending to this task
and the many people in dire need of their services.
Not surprisingly, counterinfluences sprung up that exploited
the chaos surrounding efforts to rebuild the health-care system.
For example, drugs were scarce and inequitably distributed;
therefore, drug bootleggers who charged exorbitant prices prospered. Also during this time, the terribly reprehensible practice of
replenishing the contents of discarded penicillin bottles with
burnt sugar and offering them for resale was discovered.
In all, I would say that the busy Polish physicians had many
distractions during this troubled period. Not the least of which was
the fact that the communist-dominated government was making
vigorous efforts to recruit medical professionals to its ranks with
offers of food and housing privileges. The vast majority resisted all
attempts at conversion and so the government had no choice but to
tolerate and refrain from molesting these valuable, virtually irreplaceable, members of the Polish population.

�I:Jreerpta tre• •

Letter He•e

Days Gone by, but Never Lost
During my tour of duty I traveled
widely, both in Warsaw and other
areas in Poland. The embassy provided me a car and I spent many
hours visiting the square mile that
once had been the 'Warsaw Ghetto.'
I remember climbing several tall
mounds of debris there to gaze in utter disbelief at the charred brick
and twisted steel around me. Four hundred thousand people saw life
for the last time in that ghetto, and the hot summer sun reminded
those of us still alive that all the dead had not yet been buried.
I also visited Krakow, Lodz, Zakopane and other places of
interest and notoriety, including Auschwitz (or "Oswencin" in
Polish). This terrible camp is a place I will never forget.
While I was learning firsthand about these atrocities, I also
became aware that a new version of the centuries' old tradition of
"Jew baiting" was being practiced less than 200 miles from Warsaw, in the ravaged city of Kielce. While this deeply saddened me,
it did not surprise me, as throughout my tour of duty I witnessed
hundreds of miniature conflicts involving countless bitter, disillusioned and tragic people. Once I had been in Poland long enough
to begin to see "the broad picture," it became clear to me that it
was a country that had barely begun the long process of healing.
In addition to my travels, I also had the privilege of playing
host to and providing medical care for visitors to the embassy,
some of whom were very memorable individuals. One such
person was Dr. Fronczak, health commissioner of Erie County;
Harold Stassen, a U.S. senator and then-candidate for president
of the United States; Fiorella LaGuardia, former mayor of
ew York City; and Franco Autori, conductor of the Buffalo
Philharmonic Orchestra.
Because of all these remarkable experiences-many of which
still profoundly affect me today-it was with mixed feelings that
I learned my odyssey in Poland was to come to an end in July
1947, at which time I boarded the Polish luxury liner the MS
Batory and set sail for ew York City via Stockholm. While these
are memories of a time far in the past, I was reminded just the
other day that they are still close to my heart when I recalled an
old tune, "Warszawa, Kochana Warszawa.''
"Warsaw, Beloved Warsaw.''

Morris
\Vinter

2001

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On the following pages, you will read second-year student David Flint's description of how a Medical
Student Code of Professional Conduct was recently developed at the University at Buffalo School of
Medicine and Biomedical Sciences. The formulation of the code was largely a student-driven process, and the
student participants and document architects are to be congratulated for a job well done.
The creation of such a code has been periodically suggested over the years but rejected as "something better
left to administration." The classes of 2000-2003 were up to the challenge, however, and the product of their
collective labors has won wide, and well-deserved, acclaim. As an elegant finishing touch to this
product, the code has been published as a very attractive booklet that will be distributed to each incoming class. This publication was underwritten as part of a generous unrestricted gift to the school
from Dr. and Mrs. Edward Shanbrom (Class of'S!). We are indebted to the Shanbroms for this help.
One might ask why such a code should be developed by students-or perhaps even developed
at all. The first question can be answered in a single word: empowerment. What good is such a
code if those who are obliged to follow it are not engaged in its creation?
The second question might be paraphrased as "Isn't the Hippocratic Oath good enough?" As venerable as
the Hippocratic Oath is, and even though we have modernized it to make it more contemporary, it still falls
considerably short both for the present-day medical student and for the practitioner. When UB's medical
school was founded in 1846, the states of medical knowledge and technology were such that a physician
could probably get by with
simply being a good and
moral person endowed with
a generous amount of common sense. One could occasionally do good, but the

What better introduction to the rigors ofbeing a modern
physician than a code ofprofessional conduct, created by
students for students, which places significant responsi-

ability to do harm was quite
limited. Mother

ature was

bility on the students themselves?

the great healer.
In today's world, the ability to do considerable good is more than balanced by the ability to do considerable harm, with potentially devastating consequences. Decisions about when to intervene, or "merely"
support, are critical and often difficult decisions for society, as well as for physicians. Ethical issues that our
forefathers (and foremothers) could not have imagined now confront the practicing physician on an almost
daily basis. The ability to prolong life is counterbalanced by both the finite nature of resources and the concept
of quality of life. Finally, the notion of physicians being responsible for one another's behavior and mode of
practice has now become a matter of law; and in jeopardy in most-if not all-states is the physician's right
(license) to practice.
What better introduction to the rigors ofbeing a modern physician than a code of professional conduct,
created by students for students, which places significant responsibility on the students themselves? Our
students have taken the challenge seriously, and although the actual code will undergo modification as a
function of time and the experience of implementation, it is an excellent starting place.
Again, thank you, students, for this extraordinary piece of work.

John R. Wright, MD
Dean, School of Medicine and Biomedical Sciences

�A student's perspective
on the year-long process

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CoNDUCT

By

Dav

d

Fl

nt,

Class

of 2003

, the University at Buffalo School of Medicine
and Biomedical Sciences-despite its 155-year history-did not have a code of conduct While the university at large
does have academic policies, our school did not have a code to address the special social and professional
responsibilities of medical students.
In an attempt to remedy this, Dr. john R. Wright, dean of the school, organized a committee of second -year students
in the spring of 1999 and charged us with the task of drafting such a code. (In the fall , Dr. Charles Severin, assistant dean
for students in the Office of Medical Education , expanded the committee by adding members of the class of2003. ) This
was the start of a year-long process, the final outcome of which was the development of the first Medical Student Code
of Professional Conduct for UB's School of Medicine and Biomedical Sciences.

We started at the begin·
ning, by asking ourselves,
Why do we even need a
code? On the first day of
orientation to medical
school and again at gradua·
tion, we take an oath to our
patients, peers and
medicine. But what does
that oath mean?

Open Process Key to Consensus
We started atthe beginning, by askingourselves, Why do we even
need a code? On the first day of orientation to medical school and
again at graduation, we take an oath to our patients, peers and
medicine. But what does that oath mean?
After discussing these and other questions, we decided that
our goal in creating a code of professional conduct was to
establish a set of common expectations for professional, social
and academic behavior, and to provide a framework for discussion about our roles and responsibilities as physicians.
To prepare ourselves to accomplish this goal, the committee
reviewed journal articles highlighting moral and ethical dilemmas faced by students and physicians. We also reviewed do zens
of honor codes from medical schools around the country, which
ranged from militaristic to anarchistic, and everywhere in
between. From this starting point, we then attempted to create a

document that was general enough to have longevity, but
specific enough to have practical application .
The drafting process itself was eye-opening, as each committee member brought unique skills and perspectives to the
ensuing debate about substance and form . Some of the
issues raised in our discussion seemed uncontroversial; for
example, there was limited disagreement over issues of
academic integrity. Other areas resulted in more vigorous
debate, such as, When and how is it appropriate to address
issues of substance abuse among peers? Where is the line
drawn between personal and professional life?
In order for a document like this to be supported,
there of course needs to be input from more than just
eight students and a dean meeting in a conference room.
Past attempts at creating a code of conduct at our school
had failed , which is understandable because it is a substantial task to reach consensus between students, basic
scientists, clinical faculty and administrators.
To make the creation of the code an open process,
therefore, we did a number of things: We held two

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"town meetings," which were audiotaped for those unable to
attend, and we created a webpage that allowed for critiquing of
the code, section-by-section. We also made a suggestion box
available for anonymous comments and set up an e-mail address
to receive input about the code. In addition to distributing hardcopy drafts of the code, we made copies of codes from other
medical schools available for comparison. Furthermore, Dean
Wright requested comments from the public, as well as from
readers of Buffalo Physician.
Of all these efforts, the web page was by far the most popular
medium through which we received comments on drafts of the
code. The page provided an easy way for students, staff and
faculty to comment, and also made consolidating and reviewing
comments much easier for members of the committee. (The
design and maintenance of the webpage was greatly aided by
staff in the Office of Medical Computing.)
The debate that was made possible through open discussion
encompassed a wide spectrum of issues. For example, Is it appropriate to include a portion of the Hippocratic Oath in the preamble? Should the code address the use and care of laboratory
animals? Does it adequately address sexual harassment?

oF

CoNDUCT

conflict of interest arise. ) The committee will also consist of two
faculty members and one ad hoc administrative member, as
chosen by Dean Wright. The dean's faculty representatives will
vote, but the administrative member will not.
Currently, members of the committee are working to develop
a lunchtime speaker series centered around what we hope will
be provocative vignettes that will serve as catalysts for debate
about ethical issues.
Efforts Win National Recognition
In the intervening time since the code was finalized and disseminated, our efforts have been recognized by the Association of
American Medical Colleges, the Medical Society of the State of
ew York, and the assistant dean of Mount Sinai Medical
Center, all of whom have expressed an interest in learning how we
managed this process.
Anyone who has ever served on a committee, whether in
academia or in business, understands the hurdles that must be
surmounted in order to prevent drifting deadlines and missed
opportunities. The Medical Student Code of Professional Conduct for UB's School of Medicine and Biomedical Sciences could

It is because the students, faculty and staff dedicated such a
significant amount of time to thoughtful discussion of such
issues as honor, integrity and professionalism that
today we have a Medical Student Code of Professional
Conduct that is a very powerful document.
In April2000, after more than 1,200 hours of committee time,
the student body voted to support the new code by a threefourths majority. Later that same month, the school's Faculty
Council unanimously endorsed the student-approved code.
It is because the students, faculty and staff dedicated such a
significant amount of time to thoughtful discussion of such
issues as honor, integrity and professionalism that today we
have a Medical Student Code of Professional Conduct that is a
very powerful document.
Continuing Education and Adjudication
In addition to the creation of the code itself, a legacy of this
year-long process is the establishment of an institutional body
that will have an unprecedented opportunity to take a leadership role in acting not only as an adjudicator, but also as a
continuing educator in this area. The Committee of Professional
Conduct will consist of two members from each of the four
classes, who will be elected early each fall by their peers. First-year
students will serve a one-year term, while second-year students
will serve for the duration of their medical school careers. (One
alternate will also be elected from the first-year class should a

not have been created without commitment from the school's
administration, most notably Dean Wright. As a committee, we
received exceptional support from the Office of Medical Education, especially Dr. Severin. In addition, Dr. Dennis adler,
associate dean for academic and curricular affairs, and Dr.
Nancy ielsen, assistant dean for student affairs, provided
amazing insight into the special issues arising in the clinical
years. Finally, credit goes to Junda Woo '02, whose editing
expertise helped make the code a much more readable document.
D AVID FU I\T IS CURRENTLY A SECOND- YEAR STUDENT AT THE UNIVERSITY
AT B UFFALO SCHOOL OF M EDICINE AND BIOMEDICAL SCIE CES.

Editor'sNote: The full text of the M edical Student Code of Professional Conduct can be found at http://www. smbs. buffalo. edu/
fianlCPC. htm. Readers who do not have!nternetaccess may request
a copy by calling Dr. Charles Severin at (716) 829-2802, or by
writing him at the Office ofM edical Education, 40 CPS, 3435 Main
St., Buffalo, NY 14214-3013. Beginning September 2000, each firstyear student entering UB's School of M edicine and Biomedical
Sciences will be given a copy of the code during orientation.
IV i n

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Thoughts on professionalism and empathy

Ro!IERT

\1

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Editor's Note: 011

68

\ugust 1/,2000. Robm \.,\filch,.\/[) '68, rlclnwcd
the kcmott 'n rtrt at the lliPl!lal 1\ lute Coat Cercmon~ hdd for the
mcolmllg class at the UmiWSlt~ at Buffalo School of ,\fcdtcmc and
Biomcdiw/ ~ci&lt;·nns. In the weeks followlllg the ceremony, Buftalo
PlwsiLian recei1·ed lllllltewus calls frotll indil'iduals rcqucstmg a
copy of .\Ttlch's speech and recommcruli&gt;tg that 11 he reprinted in
tht• magaztnt' (or the benefit of readers interested PI furthering
dzscusston of profemonalism ilt medrwtc. \s a rc,rdt, his &lt;pccclr i:published her&lt;!, 111 zts e11tircty
As medical dirctfor jiJr Hospice Buffalo and the Center for Hospnc
a111i Palliatn·e (an in Bul)alo, ,\ttlch Ira; garnered worldwtdc recogm
ticm for accomplishments 111 /m fteld. In I 989 he n:n ivd th· British
Fmbassv \mhassador's Award for Contnbuttcms to the Intematzonal
Hosptce ,\Towmt'ltt, and in }'}'}:; he rtCCli'Cli Cluldrcn'.; Hosptn
fllltmational s I tfctllltt \chtn•emt'llt A ward.
In a brief illfroductory talk at thc I l'hllt Coat Ceremony, Dean
john R. II nght.•\1]), explai11ed that \filch practiced as " general
surgeo11for 1;"years prior to dcudmg to pursue-full tune "a passi011
for e11d o(ltft care." He also described how \!ilch went on "to build
pwgmms of national and tnterrwtWII&lt;li rellOl\'11."
/11 addillon, 1\'nght COIItmended \filch fin Ius e!jorts to l.e/p the
medical school integrate the hosptcc program tnto its wmwlum
"Bob zs a11 iltcreclthle tndt\'l(lua/ alllla co1•tpassi01wte pln.·sicia•t,"
he concluded, "and I thmk ;n 'rc l't'ry
pril·t!eged to hal'c /u11r as our speahr
at tl11s \\'hilt Coat Ccremo 11
- S.A.U.

IT IS A PRIVILEGE TO BE PART OF THIS CEREMO Y TODAY, to
witness the inception of your professional journey.
The moment and the event are rife with symbolism, the
temptations of metaphor and allegory irresistible. But I would
like to think that we can do better than hackneyed allusions to
virginity and ship launchings, and in my attempt to do so I hope
that you will forgive me the politically incorrect use of the
pronoun "he" in reference to all the sexes.
As you know, the White Coat Ceremony is intended to emphasize the importance of both scientific excellence and compassionate care, to help "forge the contract for professionalism
and empathy" between the one who wears it and those for whom
he cares. In this, it is emblematic of the many dualities that
henceforth will be at the center of your lives, like the caduceus
with its twin serpents of knowledge and wisdom, the one useless
without the other.

In your first years, of course, your coats may be little more
than functional accoutrements, pale tokens of the ultimate
prize, a though "MD" tood for Medical Decolletage. They will
become repositories for papers and pens, handbooks and broken slides, redolent of formaldehyde and the splattering of many
labs. And they will continue to serve these utilitarian purposes.

�These coats are like the doctor's frock coat of old, worn from
morning to night in the performance of duty-a coat where he
carried his instruments and upon which he wiped his hands
and his chin; a coat that spoke to the distances he had traveled
and the wounds he had dressed-an ensign of position long
before it became a symbol of cleanliness and sterility.
But the coat also carries greater symbolism, not the least of
which may be that it is shorter than the professor's. Its stains are
the medals of struggles against ignorance and illness and suffering. It sets you apart from the bewildering cast that populates
hospitals and clinics, from other "health-care professionals"
(and, I assume, health-care unprofessionals) . It draws attention
to your duty, even in the face of your station. Its color speaks to
the purity of your purpose and pursuit. To wear it without a
sense of awe is to be a dandy-all style and no substance.
It is the badge of entry into the arenas in which you have
chosen to labor and to serve. It legitimizes your presence even as
the least of learners. It grants you privileged access to the bedside and to the patient, and from this Delphic place the chance
to glean things previously unknown. If in your first years you
learned about disease, now you can learn about illness. The
former occurs in organs; the latter, in people.
The oracle is the patient, in all his frailty and unsightliness,
whose diagnosis may be common but whose suffering is unique.
If you would meet his needs, you must go beyond the mere
proficiencies of your training. Listen to what you are hearing,
remembering that sometimes the best way to auscultate a heart
is to remove the stethoscope from your ears. Feel what you are
palpating, see the world with his vision and understand his fears,
for his fears are the manifestations of his needs. You must
understand his values and goals and make them your own,
knowing that cure is not the only legitimate outcome; if it
becomes your sole focus, you are destined to be heartbroken.
And you must be willing to share the power that is implicitly
granted the physician, whose relationship with the patient is
inherently one of inequality. Patients come to us because there
is something "wrong" with them, and we have the knowledge

and the skill they lack to make them whole once again. The coat,
which signifies the repository of that knowledge and skill, must
never become a barrier to their sharing, nor a cloak that hides
beneath it an adroit but tyrannical practitioner.
The struggle, then-and from your vantage point today you
must accept this on faith-is to stay humane, to continue to fan
the embers of compassion and empathy that lie at the heart of the
instincts that brought you here. These are fires easily damped by
the impetus to acquire knowledge and master skills. But while
the aim may be to acquire, the goal should be to dispense, and
the demonstration of those qualities of our shared humanity is
every bit as valuable, if not more so, than the ability to draw
blood or tie a square knot. It is reinforced by the recognition
that what happens at the patient's bedside is not just a function
of what you know, but of what you are.
Still, you will find that the system and the
Its color speaks to the
process often conspire against this, and, if alpurity of your purpose
lowed to, make it difficult to care. You must be
and pursuit. To wear it
vigilant to this and find ways to renew yourwithout asense of awe is
to be adandy-all style
selves by nurturing your own body, mind and
and no substance.
spirit as you would those whom you serve.
There is a world ofbeauty outside medicine,
and we do neither ourselves nor our patients justice by slighting
our involvement with it. Music resonates with our inner harmonies; art gives us fresh views of life. Read uland and Selzer and
Schweitzer, as well as the New England Journal ofMedicine. Their
science may not be as exact, but their lessons are longer lasting
and their contributions probably greater. The physicians truly
worth emulating did not have a monochromatic vision of life,
and their wisdom was enriched by the arts and their avocations
as they gained insight into themselves, as well as into their
patients. Let your coats remind you of this, especially when you
take them off.
Thoughtful men have written that the physician must also be
a priest. This is not to confuse him with the gods at whose altars
he works, or with the rituals he observes. Rather, it speaks to the
summons to heal the soul as he would the body, and, in so doing,
find the full richness of his calling. It is fitting, then, that today
you don the first metaphorical
raiment of priesthood. Today
they are those of an acolyte,
but other robes await.
4D

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Cloister Program Opens New Vistas
Three UB medical students selected as Research Scholars

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Biomedical Sciences' students Margo McKenna and
janice Sung, Class of 2003, and Charmaine Gregory,
Class of 2002, are among 40 medical students selected
nationwide for entrance into the prestigious Howard
Hughes Medical Institute-National Institutes of
Health (HHMI- !H) Research Scholars Program for
the 2000-2001 academic year.

the direct mentorship of a preceptor whom they select
from over 1,100 tenured or tenure-track intramural
scientists working on more than 2,600 research projects.
In addition to working one-on-one with scientists,
the students have an opportunity to meet and talk with
accomplished investigators at weekly lectures and can
attend national scientific meetings, NIH conferences
and workshops.

The HHMI-NIH Research Scholars Program, also
known as the Cloister Program, was established in 1985
to give outstanding students at U.S. medical schools the

Salaries and benefits for the research scholars, as well
as administrative costs for the program, are provided

opportunity to receive research training at the ational
Institutes of Health in Bethesda, Maryland. Those cho-

mentors, laboratory space and equipment and supplies
for laboratory work.

sen to participate in the program spend nine months to a
year on the

l H campus conducting basic research under

by the HHM!. The

IH, in turn, provides advisors,

The UB medical school students have settled into
their year of study and report that their experience in the
Cloister Program, to date, is everything

..

they had expected it to be.
Margo McKenna has selected Leslie
Ungerleider, PhD, as her preceptor and is

._,•

working on a project titled "Emotion
and Attention in the Human Brain: a
Functional MRI Study," which is being

-

conducted in the Laboratory of Brain

30

and Cognition, a division of the National
Institute of Mental Health. Specifically,
she and her fellow researchers are looking
at the amygdala, a region of the brain
thought to be involved in the regulation
of emotion and social behavior.
The lab specializes in using functional
magnetic resonance imaging (fMRI) to
ask basic questions about how the brain
works. "In the study, subjects are asked to
perform a task while in the scanner, and
the images that we collect can show
which areas of the brain are most active
and important for doing the task,"
McKenna explains.

Research Scholars,leh to rigbt: Janice Sung, Charmaine Gregory and Margo McKenna.

With regard to the Cloister Program,
itself, McKenna says "it's an amazing

14

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�LIKE McKE. '!\'A A:--JD SU.i\G, GREGORY FEFLS 1HE CLOISTER PROGRA~I GIVES STUDL 'TS A.' EXCELLE!\'T
OPPORTGNITI TO GAI:--J EXPOSURE TO BE:--JCH RESI:.ARCH I,' A U0.'IQUE E. 'VIRO. '~IE. '1. " P RES£. I"LY,

l A~l

• 'OT SURE IF :&gt;!Y CAREER WILL L 'CLUDE BASIC SCIE, 'CE SOLELY OR IF IT \\'ILL SO:&gt;lEHO\\' BE I 'TEGRAfED.
H O\\EVER, THERE IS i':"O DOUBT L' :\lY :\II, 'D THAT THIS IS A 0. 'CE- I, ' - A-LifETl:\lE EXPERIL 'CE A, 'D 0. 'E
THAT WILL !:&gt;!PACT 0.' :&gt;IY FL., TURE DECIS!O, 'S."

opportunity for medical students who are thinking
about incorporating research into their careers and an
ideal setting for independent thought and creativity in
the field of medicine."
Janice Sung, who is working with Bar"In the study, subjects bara Bierer, MD, in the National Heart
are asked to perform a Lung and Blood Institute on a project

task while in the
scanner, and the
images that we collect
can show which areas
of the brain are most
active and important

titled "Effect of Gelsolin on Actin Dynamics in T Cell Signaling," concurs with
McKenna. "I think the program is a wonderful opportunity to further our interests
and understanding of the basic sciences
that we were introduced to during the
first two years of medical school," she says.
"Also, living with 40 students with remarkably diverse backgrounds provides

for doing the task."

exposure to bench research in a unique environment.
"Presently, I am not sure if my career will include basic
science solely or if it will somehow be integrated.
However, there is no doubt in my mind that this is a
once-in-a-lifetime experience and one that will impact
on my future decisions."

White Family Memorial Fund Recipient

B

rian Bennett, Class of 2003, participated in the University at Buffalo

School of Medicine and Biomedical
Sciences' Primary Care Summer Externship (see article on page 22) as the first

a unique environment that is fulfilling
both intellectually and emotionally."
Charmaine Gregory is working with preceptor Marc
Reitman MD, PhD, Molecular Biology and Gene Regulation section chief in the Diabetes Branch of the
ational Institute of Diabetes and Digestive and Kidney Diseases. The project they are working on, titled
"The Role of PPAR alpha in the Hepatic Steatosis and
Insulin Resistance of AZIP/FI Mice," utilizes transgenic
mice (AZIP/Fl ), engineered in Reitman's lab, which have

recipient of the White Family Memorial
Fund. The fund-which memorializes
Deborah A. White, MD '87, and her
husband, Christopher, and son, Adam,
who died in a car accident in 1999supports a summer internship for a firstor second-year student who is interested
in pursuing a career in rural medicine.
Bennett, who is from Bath, ew York,
graduated from SU Y at Binghamton in 1998 with a bachelor

a paucity of white adipose tissue and develop an insulinresistant diabetes mellitus. The lack offat cells, according

of science degree in biology. "I was very pleased to have had

to Gregory, leads to a sequestering of lipids in the liver
and muscle. "A remarkable steatosis develops and an
impressive diabetic state evolves," she explains.

"One of my main goals throughout this past summer was to
find out if my image of a small-town physician's life was

"Peroxisome proliferator-activated receptor (PPAR) al-

day-to-day basis. I am pleased to say that my experience reinforced not only how much I want to be a doctor, but also my
selection of a small-town setting for practice.
"I can't think of a greater distinction to begin my

pha is a transcription factor that stimulates fatty acid
oxidation and peroxisome proliferation in mice. I am
investigating the effect PPAR alpha has on the steatosis,
as well as the insulin resistant diabetes in AZIP/Fl mice."
To accomplish this goal, metabolic, physiologic, and
molecular studies are being conducted.
Like McKenna and Sung, Gregory feels the Cloister

my externship placed in Medina with Dr. Madejski," he says.

representative of what a real doctor actually experiences on a

professional career," he adds, "than to receive a scholarship
in memory of the White family and connected with small4D
town medicine."
-S.A.

U!-iGER

Program gives students an excellent opportunity to gain

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Kornel Terplan Memorial Lecture

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The inaugural Kornel L. Terplan Memorial lecture was held October

Sachs Leads Collaborative Project
on Mechanical Sensitivity of Cells

5, 2000, in the lippshutz Room at the University at Buffalo School of

!:&gt;clcc t.il·, /ape

'&gt;u&lt; IH&lt;

a '' I ec 1

' o~, \fl

.s

Medicine and Biomedical Sciences. The lecturer was Donald L. Price,
MD, professor of pathology, neurology and neurosciences at the
Johns Hopkins University and president-elect of the Society of
Neuroscience. Price, an internationally renowned scientist who has
made major discoveries in the field of neurodegenerative disease,
delivered a talk titled "Alzheimer's Disease, lessons from a

has established an endowment to fund

$500,000 ove r fi ve years, University at Buffa lo and th e Massachu -

an annual lecture. Terplan's son, Martin

setts Institute of Techn ology are th e only U.S, un ive rsities selected
by the japanese Ministry for ongoi ng collabora tive projects,

Terplan, MD '55, assumed a major role in
falo to aHend the lecture, according to

The researchers will stud y the physiological p rocess by which
th e mechanical defo rmation of a cell is transfo rm ed in to elect ri cal

Reid R. Heffner Jr., MD, professor and

and chemi cal respo nses, For exam ple, mechani cal transductio n,

chair of UB's Department of Pathology.

mo re se nsitive than visio n, occurs when the movement of cells in

creating the endowment and was in Buf-

TERPLAN

japa n Science and Tec hn ology M inistry to collabora te on a
$10 m illio n resea rch p roject aimed at understanding th e m ec h-

generosity of the Terplan family, which

The event was made possible by the

L.

iop hysics researchers at Uni versity at Buffa lo's School o f

Medicine and Bio m edical Sciences have been selected by th e

ani ca l sensiti vity of cells,
Fred eri ck Sac hs, Ph D, p rofesso r of ph ys iology a nd bi oph ysics, wi ll lead th e UB project, esti mated to in volve abo ut

Genetic Approach."

KoRNEL

B

Kornel Terplan, MD, was professor

the inner ea r ge nera te nerve im pulses that res ult in th e sense of

and chair of UB's Department of Pathol-

hea rin g, Sachs and his collabo rato rs at UB discovered the firs t

ogy from 1933-1960 and served for

mechanical transducers in 1983 and, since th en, their labo ratory

many years as a pathologist at Child-

has bee n a wo rld ce nter for work o n biological mec han ica l

ren's Hospital of Buffalo and Buffalo

se nsiti vity. "In add iti o n to providin g the se nse of hearing, me-

General Hospital. A 1919 medical

cha nica l transdu ctio n also is in vo lved in to uch, th e measurem ent

graduate of German University in

of jo in t positio n, muscle tensio n, bo ne growth, blood -p ress ure

Prague, Terplan was internationally

regul atio n, fi lling of th e bladd er and intestines, and the regul atio n

recognized for his work in childhood

of cell , ti ss ue and orga nism volume an d size," Sachs explai ns.

tuberculosis and brain pathology associated with chromosome
anomalies of children. Through his work on the pathogenesis of

"Altho ugh it is an esse nti al se nso ry process, mec hani cal
transdu ctio n also ca n produ ce pa th ology. Ca rd iac fib rill atio n-

was a frequent occurrence. In 1936, Terplan recruited Ernest

th e un coo rdin ated co ntractio n of th e hea rt- ca n be initiated by
m echani cal stress,

Witebsky, MD, to the Department of Pathology. In the early 1940s

and fai lure of th e

Witebsky and Niels Klendshoj isolated the B-antigen found in

hea rt is th e most

human blood, a discovery that made blood transfusions safer.

co mmo n ca use of

TB, he proved that a reactivation of past cases of the disease

"Dr. Terplan guided the Department of Pathology through

d eat h wor ld wide.

difficult times prior to and during World War II," says Heffner,

U nd erstandin g th e

"but his leadership was even more important during the 1950s,

m ec h a ni s m s

when there was considerable change and unprecedented growth

mec hanical trans-

in medical schools throughout the country.

du cti o n w ill e n -

"Not only was Dr. Terplan an eminent scholar and one of the lead-

of

ab le scie nt ists to
rat io nal

ing figures at the medical school, he was also a man with great energy

deve lo p

and enthusiasm who was known for his personal wannth," he adds.

th erapies fo r di s-

Following his retirement as chair of the Department of Pathology

ease." (See related

in 1960, Terplan continued a productive career for another 25

articl e o n page 3 1.)

years, pursuing his lifelong interest in neuropathology.
., A. i.

T he wo rk will
be ca r ried o ut in
collabora ti o n with

16

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I

�Kavinoky &amp; Cook, said "Dr.
Riwchun felt it was very important to give back to his alma
mater and to provide training to
young
physicians. This desire to
atUB.
CD
repay culminated years later in
-LO IS BAKER
his decision to donate part of
his estate to the university, a
Riwchun Endows
desire that was ultimately carProfessorship of
ried out by his wife's bequest."
Ophthalmology
Ann Riwchun was equally
he University at Buffalo School of committed to the community
Medicine and Biomedical Sciences has and Wisbaum praised her as
received a $1 million gift to endow a pro- "a strong woman, a dedicated
Masahiro Sokabe, chair of the Department
of Physiology at agoya Medical School,
who is heading the project and who spent a
sabbatical year in Sachs' laboratory

l

fessorship in memory of internationally
known ophthalmologist, eye surgeon and
UB alumnus Meyer H. Riwchun, MD '27.

mother and wife, and active
civic leader." She was the first woman to

Hospital and at Children's Hospital of Buf-

serve as president of the Buffalo Association

falo during the 1960s. Riwchun was attend-

for the Blind, and was honored by many

ing ophthalmologist at the then-Deaconess

organizations for her civic leadership. In
B
1979, the Riwchuns were

Hospital and attending ophthalmologistin-chief at the former Rosa Coplon Home.

The gift-a bequest from Riwchun's
wife, Ann S. Riwchun, who died in 1999will fund the Meyer H.
Riwchun Professorship
of Ophthalmology in the

"

jointly named Buffalo

During World War II, he was a lieutenant

News Outstanding Citi-

colonel assigned as chief of eye services at

zens for their work with
the blind. John R. Wright, MD, dean of the
School of Medicine and Biomedical Sciences,
hailed Riwchun as "a leader in the field of eye

Walter Reed Hospital in Washington, DC.

l

C•~MBE

Department of Ophthalmology. Ann Riwchun made the bequest to
recognize and continue the work that her
husband had pursued as a professor in the
medical school, in his private practice and as
head of eye services for the U.S. Armed
Forces during World War II.
"Dr. Riwchun was a highly regarded
ophthalmologist and UB graduate who enjoyed a long and distinguished career in
medicine, while his wife was equally dedicated to civic activities," President William
R. Greiner said at the time the bequest was
announced. " During their lives, they
made a real difference in the quality of life
for Western ew York residents and con-

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His patients ranged from enlisted men to
such high-ranking officers as General of the
Army George C. Marshall, as well as Ameri-

care, whether he was using innovative surgical can and foreign diplomats, including Soviet
techniques or educating medical students and Foreign Minister Andrei Gromyko.
Along with maintaining a private practhe public about the issues of good eye care.
tice,
Riwchun taught at UB as a clinical proThis gift will allow UB to carry on that legacy
fessor
in surgery and ophthalmology, was
ofleading-edge education in ophthalmology."
chair
of
the Department of Ophthalmology
Wright also said he expects the Riwchun
and wrote numerous scientific papers on
Professor to be named by September 2001.
Riwchun, who died in 1998 at the age of eye disorders and eye surgery.
The Riwchuns' leadership gift goes to95, earned his medical degree from UB in
cialists in Austria before returning to Western ew York for a long career in medicine.

wards meeting the School of Medicine and
Biomedical Sciences' goal in the campaign for
UB: Generation to Generation, a $250 million

tinue to do so through this generous gift."
The Riwchuns' long-time friend and at-

He maintained a private practice from 1929-

university campaign. Funds raised will be

1985, also serving as head of the departments

torney Wayne Wisbaum, a senior partner at

of ophthalmology at The Buffalo General

used to enrich academic programs, support
students and enhance university life. CD

1927, and then trained under European spe-

Wint e r

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Distinguished Medical Alumnus Named
Do.wld Ptt

.L., ,\[/) .~ ••

pct.l£... 1( vllCo!ogts.

W

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UB Hosts
International
Epidemiology
Conference

tures can work

to improve the

effectiveness of ISEE chapters in
latin America , the Caribbean,
Central America, Africa, and

Univer-

The 12th annual meeting of the

Central and Eastern Europe,"

sity Medical School and a renowned specialist in pediatric oncology,

\II)

International Society for Envi-

explains Vena.

received the University at Buffalo's Distinguished Medical Alumnus

ronmental Epidemiology (ISEE),

Conference cochairs, in addi·

Award from the Medical Alumni Association at a dinner September

hosted by D. John Vena, PhD, of

tion to Vena, were John Weiner,

28, 2000, in the Buffalo Club.

the Department of Social and

DrPH, and Germaine Buck, PhD.

I'

PROHSSOR OF Pill I ITRICS at Texas A&amp;M

A Buffalo native, Pinkel received a bachelor's degree from

Preventive Medicine, was held

For the full program and ab-

Canisius College in 1947 and a medical degree from UB in 195 L He

August 18-22, 2000, at the

stracts, visit the conference web-

served his residency at Children's Hospital of Buffalo, and was a

Adams Mark Hotel in Buffalo,

site at: http://www.phoenixwork

research fellow at the Children's Cancer Research Foundation in

New York.

group.comlisee2000.

Boston, now Dana-Farber Cancer Institute.
Pinkel returned to Buffalo in 1956 to start the pediatric department at Roswell Park Cancer Institute. In 1961, he was appointed

and 92 students from 45 countries attended the meeting, where

the founding director of St. jude Children's Research Hospital in

some 350 papers and three poster

Memphis, the first institution devoted solely to basic and clinical

sessions were presented on the

pediatric research.

theme of "Environmental Epide-

ing members of the Class of

miology in Pan America and the

200 I, who were recently in-

Since leaving St. jude in
1973, he has accomplished a va-

Left to right: Dean John R. Wright, Dr. Donald
Pinkel and Dr. John Bodkin

World: Building Connections."

riety of tasks, including rejuve-

"The purpose of the meeting
scientists and students from

CHRI'&gt; TOP H E R ADA\1'.

Midwest Children's Cancer

around the world to exchange

TH O \IA S BLA C K

Center in the city; developing

ideas for cutting-edge research in

)OHS B O RGO \

pediatric leukemia research

the field of environmental health,"

TH O \IA'o B OTT A

programs at City of Hope

says Vena, who adds that the event

MARIS A BRA \ "IS

Medical Center in California and

was tremendously successful.
The primary goals of the con-

in Houston; and, as medical
director, taking a key role in

ference were to showcase ongoing

BARB A RA GR EE SB E R(,

interdisciplinary, international

AAR O S GL YE R

rebuilding St. Christopher's

epidemiologic research and to

KEI IS M O LLE:\
ELYSSA PE T ER'.

facilitate more collaboration in

KILl-IS S .H E RS O

research and training worldwide.

Award for Medical Research, the Kettering Prize for Cancer

opportunity for the scientists to

Research from the General Motors Cancer Research Foundation,

highlight emerging global envi·

the Zimmerman Prize for Cancer Research, the Biennial Winder-

ronmental health issues, ex-

mere Lectureship of the British Pediatric Association and the

change the latest scientific

Return of the Child Award from the Leukemia Society of America.

findings and methodological

An upcoming issue of Buffalo Physician will feature an in-depth

approaches for a wide spectrum of

article on Dr. Pinkel's career, including many fond memories he has

environmental exposures and re-

of his days in medical school at UB, as well as in training at

lated health outcomes, and to talk

CD

Children 's Hospital of Buffalo.

about ways in which organizational and administrative struc·

- L O I S BAKER

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SA SHA GIL\I ORE

provide a forum to discuss how to

"The meeting also provided an

\\' 1 11

RYAS DFSHAE SE

M.D. Anderson Cancer Center

Pinkel has received many honors, including the Albert Lasker

y sic i a a

Alpha Omega

was to bring together distinguished

sor of pediatrics at the University of Texas Medical School in Houston.

n

ducted into

Alpha this past fall.

nating Milwaukee Children 's

In addition to his post at Texas A&amp;M, he currently serves as profes-

I a If ale

Congratulations to the follow-

Hospital and establishing the

Hospital for Children in its North Philadelphia neighborhood.

18

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Approximately 400 scientists

Alpha Omega Alpha is the only
national medical honor society
in the world. Its purpose is to
recog11ize wtdergraduate medical school achievement and to
perpetuate excellence in the
medical profession.

�A:z:odo Completes Alpha Omega Alpha Fellowship
L
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2&lt; 2, is the recipient of an Alpha Omega Alpha Student Research
Fellowship, which provided him with $3,000 in support of a research project he completed
during the fall of 2000 in the laboratory of Wesley Hicks Jr., MD '84, DDS, at Roswell Park
In his research project, Azodo focused on understanding why
granulomas form in the airway of cancer patients who undergo radiation therapy or have tumors surgically resected. Specifically, he worked
to characterize the role of IL-l, an endogenous cytokine, in the response
of tracheal respiratory epithelial cells (RECs) to injury.

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"We were trying to see how blocking IL-l or changing its concentrations affects the growth of porcine tracheal RECs, used as a model for
human cells," explains Azodo. "IL-l is known to be an endogenous

"

result of signal transduction from membrane receptors. It also modi-

....

fies the activity of several known mitogens and chemokines. In

..

First-year student Diana Pratt is
this year's recipient of the Univer-

Cancer Institute.

..

Medical Alumni
Association
Scholarship

pyrogen and has many effects, both directly on the nucleus and as a

particular, it plays a major role in the early attraction of neutrophils
to the site of inflammation, which accounts for some of its destructive
involvement. This investigation is complicated by the presence of two
distinct sub-populations-IL-l alpha, and IL-2 beta-each with different proportions, sites of
action and mechanisms of regulations."
Originally from igeria, Azodo lived in Rochester, New York, for seven years prior to
coming to the University at Buffalo in the fall of 1994 to begin work on a bachelor of arts
degree in biology, which he completed in the spring of 1998.
Currently, he has a strong interest in pursuing a career in radiology and says he would like
to complete a residency somewhere in the southeast or mid-Atlantic, if he does not remain
in Buffalo.
"As an undergraduate, I had several opportunities to engage my talents and interests outside
of the classroom, and I worried that my involvement in these activities would end when I
began medical school, but I was wrong," says Azodo. "In my second year, I began a Radiology
Interest Group (RIG) that has been recognized by the Polity [the medical student governing
body]. The group now serves to introduce medical students in the preclinical years to this
innovative and integral part of medicine as it is practiced today."
In his second year, Azodo also had an opportunity to serve as vice president of the Student
ational Medical Association (S MA). As the junior branch of better-known National

sity at Buffalo's Medical Alumni
Association Scholarship. The
scholarship is made possible by
the generosity of alumni through
their reunion gifts designated to
the Medical Alumni Association
endowment fund.
Recipients are
selected by the
admissions committee according
to considerations
of financial need
and academic merit based on the in·
coming student's
applications.
Pratt, a native
of Buffalo, New
York, graduated
from UB in 1999
with a bachelor of science degree
in biomedical anthropology. At
this point in her education, she is

..

interested in pursuing a career in

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family medicine, but plans to remain open to other possibilities,
including international medicine.

I

-5. A. U:-.:GER

Medical Association, the S MA provides an avenue for minority medical students to explore
the unique contributions they can make to medicine, according to Azodo. "Through collaborative efforts with other groups during the 1999- 2000 school year, we introduced several non -

....

minority students to the S MA," he says. "We also provided insight into what minorities
could offer the medical community at all levels. In part, we accomplished this by discussing
the prevalence of major diseases such as lupus and diabetes in the minority community and
by sponsoring lectures, including one by Dr. Paresh Dandona that was well attended.
"My work with the RIG and the S MA are just two examples of the kind of overall growth I
have experienced and come to value during my time in Buffalo," Azodo continues. "On the
whole, UB has been a wonderful place for part of my transition into adulthood."
-5. A.

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Honors Brunch Recognizes first·
and Second·Year Achievements
!I F A

U-\I

HO'\ORS BRc ( H recognizingacademicexcellenceamong Kathleen O'Donnell, '02,

first- and second-year students at the University at Buffalo School
of Medicine and Biomedical Sciences was held October 22, 2000.
The following is a list of award recipients and a description of
the awards received.

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The Department of Pathology's
American Society of Clinical
Pathologists Award for Academic
Excellence, which is presented
to the second-year student who
has demonstrated high academic achievement and outstanding performance in the

KATHLEEN o ·oo"&lt;ELL

Departmental Awards

Kelly Gordon, '02, received

The departments of the School of Medicine
and Biomedical Sciences have established
awards, described below, to recognize merito-

the Department of Microbiology's Ernest Witebsky
Award for Proficiency in

rious performance in courses and outstanding
achievement in wrriculum-related activities.

Microbiology, which is

Pharmacology and Toxicology's Edward A.

given to the second-year

Carr, Jr. Clinical Pharmacology

pathology laboratory.

Brian Maim, '02, received the Department of

student achieving the

Award and the DouglasS. Riggs
Award. The former award is

of Anatomy and Cell Biology's Gibson-

highest grade in the
microbiology and immu-

Atwell-)ones Award, which recognizes the

nology course. Dr. Witebsky was the found -

achieving the highest average in

student with the highest com-

ing chair of the Department of Microbiology.

Richard Newell, 'OJ, received the Department
L

received

KELLY GORDO N

bined average in the anatomical

given to the MD/PhD student
the Fundamentals of Pharmacology course, while the latter is

sciences courses of gross ana -

Christine Kerr, '02, received

tomy, histology, neuroanatomy

the Department ofMicro-

and embryology. The award is

presented to the second-year
student with the highest average

BRIAN MALM

biology's Marek Zaleski

in the course. Drs. Carr and Riggs were

named in honor of past chairs of Award, which is presented

chairs of the Department of Pharmacology

the department: james A. Gibson,

to the student who best

Wayne ). Atwell and Oliver P.

combines high standards

and Toxicology.
Maim also received the Department of

)ones.
ewell also received a
McGraw-Hill Book Award, which is given

of academic achievement
with outstanding service

to the two highest-ranking students in the

to the community. The
second-year class chooses the recipient.

RI C HARD NEWELL

first-year curriculum.

Pathology's john B. Sheffer Award, which is
C HRI STil\ E KERR

given to the second-year student who has
performed at the highest level in the laboratory portion of the courses in general and
systemic pathology. Dr. john Sheffer prac-

Sara Kaprove, 'OJ, received the Department of Christopher Mutty, '02,

ticed pathology in Buffalo for over 35 years

Biochemistry's Edward L. Curvish Award,
which recognizes the student with

received the Department
of Pathology's Kornel

and was acting chair of the Department of

the highest average in the two

Terplan Award, presented

first-year biochemistry courses.

to the student with the

Kaprove also
McGraw-Hill

received a

Book

Award,

in the two second-year
pathology courses. Dr.
Terplan was a past chair of
the department.

first -year curriculum.

S AR A K A J&gt;ROVE

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highest combined average

which is given to the two
highest-ranking students in the

Pathology from 1972 to 1974.

1
C HRISTOP HER Mt:TTY

�the student with the highest combined average in the two physiology courses in the
first year. Dr. Rennie was a former vice president for research at UB and chair of the
Department of Physiology and Biophysics.

Discipline Honorary Societies
A:-.; JEll

GL:PT A

The Association of Pathology Chairs Honor
Society awardees were Christopher Mutty, Brian

JI LL ALB R EC H T

L AL R A

C u..:S KJ

Anne Wolpiuk , '02, Robyn Filipink, '02, and Maim, Kathleen O'Donnell, Jennifer Defazio, Diane Jill Albrecht '03, and Laura Cinski, '03, received
Anjeli Gupta, '02, received the AstraZeneka Den Haese and Linda Cuomo, all the Class of 2002. the Evan Calkins Primary Care Achievement
Cardiovascular Drug Monograph Award

Award, which is given to one or two

given to second-year students by the Depart-

outstanding students in the Primary

ment of Pharmacology and Toxicology. The

Care Summer Externship Program.

award is based on the quality of a mono-

Calkins is a former chair of the

graph written in the form of a package insert.

Department of Medicine.

4:D

Carlos Cedeno, '03, received the Department
of Physiology and Biophysics' Donald W.
Rennie Physiology Prize, which is given to

J•""" •• DEFAzio

Dean'sLetters of Commendation, 1999-2000

M ELII'DA K NOX

Class of 2003

T ODD ) AN I C KI

The Dean 's Letters of Commendation are awarded to students who

D A\'ID K RAKOWSKI

) or'EL B ALLARD

SARA K APRO\'E

achieve 75 percent of available honors points in each year. Two
honors points are earned for each credit hour ofhonors performance

C H RI STOPHER A DA~IS
M ARll'&gt;A B RA\'1:-1
B ARBRA G REE:-.'BERG

Class of 2002
VI CTOR A MODEO
G ARRICK A PPLEBEE
S L'Z IE A RIY ARATANA

E LIZABETH B OLRKE

) E,.N I FER K ORZEN

B RI Al'&gt; M AL~!

) AMES B onE

) A~IES LI N
ATAS H A M A"ES

A "THO" Y M ATO

CARLOS CEDEl-&gt;0

C H RISTOPHER M LTT\'

KI T C HENG

RI CH ARD

K AT H LEEN O ' D oNNELL

C H RI ST INA CLAR K

) EFFREY

) El-&gt;NIFER D EF AZ I O

CARYN O RR

D AN IELLE D oRsA:-.Eo

T IMOTHY P ARDEE

D IANE D E. · H AESE

P HILLIP S EEREI TER

L ISA E sLER

E LIZABETH P ENDER

M ELISSA D ESANTI S

S ANDES H S ING H

E sME F INLAY

E RIC SCHAEFER

K EELY D WYER- M ATZ KY

) ON \THAN S IUTA

D A\'ID F l"TAK

D A\ ID S CHLESINGER

M ELANIE FI ORELLA

) ULI E V OGEL

while one point is earned per credit for high satisfactory.

Class of 2001

CHRI STOPHER L OGUE

EWELL
ORTH

K ARA G ROSS

M ARC. A UERBACH

R OBYN F IUPI:-.' K

AIM EE STA" I SLAWSK I

A ARON G uYER

SHALEE~ B ELA'!

CHRISTOPHER F ORESTO

A NDREI\' SWAN

D A\'ID F LINT

B oBBI W Ax

K E\'1' M oLLEt&lt;

LI LY B ELFI

A LICIA G ITTLEMAN

A NDREW Sn1oNs

A LFRED F RONTERA

L YNDSAY WIL LMOTT-

E LYSSA P ETERS

S\'ETLAl'&gt;A B LITSHTEY~

K ELLY G oRDON

E ~11 LY T ENNEY

) ULIE G A\' I N
LI SA G ELMAN

KI LIAN SALERNO

VI TO B RL'NETTI

G REGO RY ) ANIS

M ATTHEW T RAUGOTT

) ERR\' CHANG

K YLE K ATO~A

) ULIANE T HuRLOW

D A\'ID G RAY

L INDA CuoMo

D A\' I D K IM

K ARES W EISS

H OWARD H AO

B ARTOS
R oss Y APLE

STEVEN W E I TZ~IA:-.'

l

l

Honors Brune
1V i11 t er

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The Primary Care Summer [xternship Program
" Truly taught me what it takes to be a fine physician "

0

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Summer Externship Program has offered first- and
second-year students a paid six-week experience during
the summer months. Through the program, medical

Through the Eyes of Students ...
The following comments were made by students who
participated in the 2000 Primary Care Summer
Externship Program.

students are placed in the offices of generalist physicians
across Western ew York, where they enjoy varying
degrees of interaction with patients, including taking
histories and performing physicals.
The externship experience clearly has a positive im-

.lennifer K. Kor:z:en, Class of 2003
P Rl c F PTO RS:

pact on student participants. In reviewing results of the
program over the last three years, we found that 96 percent of externs "agreed" or "strongly agreed" that their
clinical teachers improved their understanding of clinical

"I am now only beginning to grasp all that I really learned

practice (such as physical exams, medical decision making, treatment options, etc.). We were also pleased with

this summer. Whether it was on the pathophysiology of

the results of comparing pre- and post-externship surveys.

how limiting HMO drug formularies can be, or how

Twenty-seven percent of students felt that prior
to the externship they had a broad or very broad

much some patients really need reassurance from their
doctors, I know my time at Geneva B. Scruggs Health

exposure to career opportunities in primary care

Care Center has been one of the best learning experiences

We found that 96
percent of externs
"agreed" or "strongly
agreed" that their
clinical teachers
improved their

type II diabetes, how to comfort a patient who has HlV,

compared to 64 percent, post-externship. Since

of my medical school career thus far. I do not think I will

the program's inception in I 993, 67 percent of

ever really be able to thank Dr. Gbadamosi, Dr. Lewis, or

primary-care externs have entered generalist

Susan [Ba ran ] enough for being able to watch them and

residency programs, compared to 48 percent of
the entire University at Buffalo graduating class

work alongside them this past summer, for they have truly
taught me what it takes to be a fine physician."

during those years.
We are grateful for the support of the various

understanding of

program sponsors, including the

clinical practice.

tion (whose significant three-year grant ended this
past summer) and the Robert Wood Johnson Foun-

ulpeper Founda-

dation (whose Generalist Physician Initiative grant also
ment of Health, the Western

.leffrey Conklin, Class of 2002
PRECIPT OR:

Fra11k C. Mezzadri, MD

"One of the nice things about working for a large group

ew York State Depart-

practice like Quaker Medical Associates (QMA) was the

ew York Rural Area Health

chance to see different styles of dealing with patients and

ended). Other sponsors include the

Education Center and the White Family Memorial Fund.
In addition to foundation and institutional support,

hearing various perspectives on medical topics ranging from
the diagnosis and treatment of patients to managed care. I

the Primary Care Summer Externship Program welcomes

left each day with at least one new insight that will help me a

support from individuals; for example, Evan Calkins, MD,

great deal once I get into practice.

has established a special endowment fund to develop a

confirmed my desire to work in the primary care setting and

Externing at QMA

more consistent funding source for the program. For more

to treat both adults and children, and it also gave me a sense

information about the program or giving opportunities,

that I would really enjoy working in a group practice, assum-

contact the Office of Medical Education at (7 16) 829-2802.

ing I have the opportunity to choose my career path."

-DFBRA STA~tM,

22

Fatai Gbadamosi, MD,
Dwight Lewis, MD, a11d Susn11 Barnn, PA,
Geneva B. Scruggs Health Care Center

laflal1 Hysiciaa

\\'t11tcr

200/

DirectorofStudelll Services

�Student

Preceptor

Speciality

MAL'REES GROSSI

Drs. Colleen Mattimore
&amp; Mary Schamann

Pediatrics

MARK HAG(,ERTY

Dr. Edward). Graber

Internal Medicine

KESSETH HALLI\\"ELL

Dr. Sanford Levy

lttternal Medicine

CHRIS "CARL"
RE\SOLDS

Dr. Richard Castaldo

Internal Medicine

Scon HoRs

Dr. Richard Castaldo

Internal Medicine

STE\"ES KA\1

Dr. Donald Robinson

Family Medicine

pediatrics and my desire to pursue this field, but also taught me a

ILSTIS KA:&lt;ALEY

Dr. Raphael Wang

Pediatrics

wealth of information about how to be a good clinician and
communicator with both children and their parents."

)EsstFER KoRZE:-&lt;

Drs. Dwight Lewis

Family Medicine

.Justin Kanaley, Class of 2003
PRECEPTOR:

Raphael Wang, MD, Williamsville Pediatrics

"Beyond the one-on-one teaching that I received from Dr. Wang,
I was able to become part of a team of health-care providers who
made the office run very smoothly. Every nurse, nurse practitioner,
secretary and doctor at Williamsville Pediatrics went out of his or
her way to make me feel comfortable in the office. When my sixweek externship was finished, I didn't want to leave, for I truly felt
that I had become a part of their team. The experience that I gained
from this summer program not only emphasized my love of

&amp; Fatai Gbadamosi

ROSA'" LASA

Dr. Theresita Dolojan

OB/GYN

ALEXASDER LERSER

Dr. john Fudyma

Internal Medicine

he Primary Care Summer Externship Program wishes to

MARA Ltsscon

Dr.) . Thomas Reagan

Family Medicitte

extend a sincere thank you to all the preceptors, listed

CrsTHIA MARTISEZ
-CAPOLI:-&lt;0

Dr. Ellis Gomez

Family Medicitte

MATTHE\\ McKES. 'A

Dr. Gregory Snyder

Family Medicine

MORCOS MORCOS

Dr. Khalid 1ahran

lttternal Medicitte/
Nepltrology

HEATHER MoRGASTI

Dr. Lawrence Me ally

Pediatrics

MICHELE 0DROBISA

Drs. john Brewer,
Roberta Gebhard
&amp; Kim Griswold

Family Medicine

THANK

You,

PRECEPTORS . . . .

T

below, who continue to make this program a success.
Many of these physicians volunteer their time year after
yea r to ensure that students experience the true practice
of medicine early in their careers.
Student

Preceptor

)ILL ALBRECHT

Dr. M. jane Parmington Pediatrics

DA:-&lt;IELLE A:-&lt;&lt;.,LI\1

Drs. Russell Vaughan
&amp; Lorie Leonard

Pediatrics

SL SIL BAS SAL

Dr. john Thompson

Family Medicine

LL'CIA PHROSE-Gtuo Dr. Mark Swetz

Family Medicine

Dr. Thomas) . Madejski

Internal Medicine/
Geriatric Medicine

)ES'\IFER PAYSE

Dr. Arnold A. Abramo

Pediatrics

Drs. Thomas R. Gerbasi

Pediatrics

MICHAEL CHILLSGL'

Dr. jack P. Freer

Internal Medicine

L•LRA Ct:-&lt;SKI

Dr. Sharon L. Ziegler

Family Medicine

)EFFREY CosKus

Dr. Frank C. Mezzadri

Medicine/Pediatrics

LtsDA CL'0\10

Dr. Thomas S. Scanlon

Internal Medicine

Dr. Howard Sperry

Internal Medicine

AIRANI SATHASATHA'\ Drs. Catherine O'Neilt
&amp; Janet Sundquist

Intemal Medicine

)E:-&lt;SIFER DEFAZIO
BETH DmiARACKI

Dr. David james

Family Medicilte

RACHEL SCH\IITT

Dr. William Kuehnling

Family Medicine

DASIELLE DoRSASEO

Dr. Peter Kowalski

Family Medicine

)OS ATHAN Stl'TA

Dr. Peter Winkelstein

Pediatrics

MOLLY E.nos

Dr. Rodney Logan

Family Medicine

STEPHES TL'RKO\KH

Dr. Mark R. Klocke

Pediatrics

GEOR&lt;,E FtuL"EROA

Dr. Anthony C. Sorge

Internal Medicine/
Pediatrics

SHA\\S VAISIO

Dr. Frederick Downs

Family Medicine

MtCH"\EL WHITESIDE

Dr. David Milling

Intemal Medicine

Dwm Ft:-&lt;TAK

Dr.

Medicine/Pediatrics
Intemal Medicitte

Dr. G. jay Bishop

l111emal Medicitte

LYSDSAY \\'tLL\tOTT
-BARTOS

Dr. Charles Hershey

SEAS GARY!.
CHRISTISA GRACZYK

Dr. Michael) . Aronica

Medicine/Pediatrics

Tt:&lt;A WL'

Dr. Lorne Campbell

Family Medicine

Speciality

A\tY PLZIO

icholas Aquino

&amp; Shawn Ferguson

)A\IISOS RIDGELEY

Dr. Anthony
0. Bartholomew

Itttemal Medicine

ELENA SALKO\"SKY

Dr. Ashok

OB!GYN

ll'i11ter

aik

2001

1 1 11 111 Hysic i aa

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Mini-Medical
School Thrives
Gift from Davises supports school and new office

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free to high school students enrolled in the Buffalo, Lockport,
West Seneca and Williamsville school districts. Students are presented a curriculum focusing on the real-life applications of the
sciences, which they in turn share with lOth graders at their school
after completing the semester-long program.

Retired business executive and community leader

In addition, the Mini-Medical School hosts a

Donald L. Davis and his wife, Esther, have made a

Mini-Veterinary School, now in its third year, which

$600,000 gift to the University at Buffalo's MiniMedical School, a highly popular, public-service

medicine and pet health care. Also, in the spring of

program presented by

B ,
f

D

offers a five-week slate of courses in veterinary

l

\\

the School of Medicine

R
5

2000, in collaboration with the UB Law School, a

K

program based upon a series of medical-legal

and Biomedical Sciences.

vignettes and specifically targeted to the legal profes-

Long-time benefactors of

sion was launched.
Graduates of both the medical and veterinary

the university, the Davises have reached the
$1 million mark in their support of UB with their
most recent gift.
"The Mini-Medical School fits our guidelines for

Esther and Donald L. Dnis

benefiting the community and the university," says
Esther Davis. "It has a very good format, builds on the strengths
of the university and extends that knowledge to the community."
"The university is the greatest thing that has happened to our
area," Don Davis adds. "We wanted to do something that would
benefit the entire community."
In addition to guaranteeing support for the Mini-Medical
School for the next I 0 years, the Davises' donation has also helped fund a new public-access office for the Mini-Medical School at
101 Farber Hall, directly across from Butler Auditorium where
the school's programs are conducted. During a ribbon-cutting
ceremony held on September 26, 2000, for the new office, Harry
Sultz, DDS, MPH, director of the Mini-Medical School, welcomed
and thanked the Davises, whom he referred to as "among the most
generous, public-spirited citizens we have in Western

ew York."

The Mini-Medical School- which was started by Sultz and his
associate Alan Reynard, PhD, in I997 as "a shoestring operation"-

programs are eligible for membership in the MiniMedical School Alumni Association-the first of its

kind in the nation-which provides additional
science-related programs, clinics and tours, as well as discount
enrollment for future programs with the school.

Musicians, artists, dancers,
actors, athletes, scholars ...
we all love Nichols.
• State of the art visual and
performing arts center
• Exceptional college
placement record
• Challenging curriculum with 17
advanced placement courses

has been a highly successful endeavor by all measures. To date,

• Comprehensive community
service program

over 2,000 participants have attended its programs, making it one

• More than 60 sports teams

of the most popular and far-reaching community services at the

• Average class size of 15
• Financial aid available

university. In March 2000, the success of the school was formally
recognized by Business First, Western ew York's business journal,
when it named Sultz a "Health-Care Hero."

On!v one invesrment
lase; a liferime

In its core program, the Mini-Medical School provides a series
of lectures dealing with subjects traditionally covered in medical

Coeducational grades 5·12

875-8212

school, but geared to helping the public understand the science

1250 Amherst Street
Buffalo. NY 14216
www.nicholsnet.net

behind the medicine, according to Sultz, who is also dean emeritus
of UB's School of Health Related Professions and professor
emeritus in the Department of Social and Preventive Medicine.
Building on the success of this format, the Mini-Medical School
has expanded its offerings to include the High School Science
Enrichment Program, which was begun in the fall of 1999 and is

24

c::J:)

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2 001

NICHOLS
SCHOOL
Acceptance granted to qualified students
Without regard to race, color, religion or
national origm.

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Gifts for Generations to Come
By Li nda J . Cor de r , Ph0, CFRE

0? 1\l l \L 'Cl )
Campaign for
DB-Generation to Generation was exciting. The Dean's
Advisory Council and Campaign Steering Committee
were on hand for special meetings with Dean Wright, a
luncheon hosted by President Greiner and a universitywide reception.
Our school is poised to top its original goal ($40
million ) shortly, due in part to grants its outstanding
faculty receive from nonprofit organizations and private
foundations. Thus, the committee agreed to raise the goal
to $50 million. Gifts from individuals are increasing as
more people realize the small percentage of the budget
that comes from state appropriations (about 12 percent).
What a tremendous difference philanthropy m akes to
an institution like UB!
Best of all, there are ways to give that benefit donors
as much as their contributions enrich the school. After
the kickoff, I was asked several questions regarding charitable trusts. While continuing to respond personally to
requests, this column also provides a way to share some
quotations about unitrusts that one of our alumni wrote
to some of his friends.
He warned me that including it here might signal the
end of the long-running bull market. However, with the
market's constant ups and downs in recent months, neither of us could be blamed for a change in its direction.
He begins: "Eat your cake, have more of it and
benefit UB Med," and continues:
If you are a UB graduate in your fifties or older, there's
an excellent chance that your kids are educated to the hilt,
off on their own and doing well. There 's also a possibility
that you may have bought stock that has gone up tenfold
or more. If this applies, read on ...
The Charitable Remainder Unitrust is a nifty invention.
You not only get out of the tax you would owe if you sold it

in value of the original stock purchase. The older y ou are,
the larger the deduction , because you have less time left, less
time to do something nice.
Here's another feature: The winner that you select

probably pays a skimpy dividend-or none. The charitable unitrust will pay you five
percent [possibly more]. This
may come at a time when you
GI FTS FROM I:&lt;DIVIDUALS ARE
would like to have more money
INCREASING AS MORE PEOPLE
because of cutting back on your
REALIZE TH E S~I ALL PERCENT income-or the inroads of
AGE OF THE BUDGET THAT
managed care.
COMES FRO~t STATE
Is a charitable remainder
APPROPRIATIONS (ABOUT 12
trust complicated to set up? Will
PERCENT) . WH AT A
you have to go to a lawyer (which
you hate to do )? Heck no. It's
DIFF ERENCE PH ILA NTH ROPY
pretty much an off-the-shelf, fillMAKES TO A:&lt; INSTITUTI ON
in-the-blanks product. UB will
LIK E UB!
help. So will I, a retired simple
B EST O F ALL , TH ERE ARE WAYS
country doctor who started on
TO GIVE THAT BENEF IT DONORS
the path at the noble building
AS M uC H AS T HEIR CONTRI BU on High Street . . .
TI ONS ENR IC H
He ends with: Tell me about
T HE SC H OO L.
your big winner, brag about your
class and I'll brag about mine . .. "
I agreed to pass along letters
if anyone wants to write to our "Dr. Feelgood. "
This campaign provides opportunities for
making gifts that will enhance the academic
environment for this generation of students and
those in the future. If you would like to find out
more about the school's dreams or perhaps see an example of how a unitrust, or other charitable trusts, might
benefit you and those you love, give me a call. The cam-

[the appreciated stock], but you 'll be rewarded with a de-

paign will continue through 2003 . Your benefits could last
a lifetime; your legacy to the school would last forever.

duction for your upcoming income tax return (s). The

Linda]. Corder, associate dean, can be reached toll free at

amount of the write-off is a generous portion of the increase

1-877-826-3246, or e-mail her at ljcorder@buffalo.edu.

W i nt e r

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�OLYMPIC

FENCING

COMPETITION

~-ent
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THOMAS

UB intern competes on Olympic fencing team
NN MARSH WENT TO THE OLYMPICS last September and almost brought
back the most rare of souvenirs.
An emergency medicine intern in University at Buffalo's Residency Consortium,
Marsh was one of three members of the U.S. fencing team that placed fourth in the
2000 Summer Games' team competition in Sydney, Australia. After their comefrom-behind win over fourth-seeded Hungary in the quarterfinals, the Americans
lost an oh-so-close bronze-medal match to Germany, 45-42. It was the U.S. team's
first-ever medal-round appearance in Olympic competition.
"We would really have liked to have won a medal,"
says Marsh, who was participating in her third Olympic
competition. "But we had a very good result. It was a
big step for us to beat Hungary-the biggest win we've

fitting exit from a sport she has pursued with a passion
since the eighth grade in her native Michigan. Fencing's

ever had."
For the U.S., this win also represented a giant step
toward legitimacy in the sport of fencing, which has
long been dominated by Europeans. In fact, Marsh and

with muscles," though Marsh dismisses that with a
laugh-"more like high-speed checkers," she quips.
"You're really trying to fake out your opponent,"
she says of the sport's mental aspects. "Are they really

her teammates-sisters Iris and Felicia Zimmerman of
Rochester, New York-left Sydney knowing that their

going to be smart enough to try that move, or are they
just trying to make you think they'll try it?"

performance had won the sport new respect in the

Fencers wear wire-mesh protective gear and scoring
is kept by electronically registering "touches" that are
made with the point of the foil. In individual competition, bouts are to I 5 points.

United States.
Marsh also placed I 6th in the individual foil competition. (The foil, a light, flexible weapon with a rectangular blade, is one of three weapons used in the sport.)
If these Olympic games were Marsh's last-as she
says they probably were-then she certainly made a

26

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demands are many: quickness, agility, strength, balance
and mental dexterity. The sport has been called "chess

Team contests, in turn, are relay affairs in which each
of the opposing teams' three fencers goes against one
another. It can be grueling both physically and

�emotionally, and Marsh says she gets sore during competitions from the tension.
A competitor who is known for her always-attacking
style, Marsh admits to having no patience with the careful parrying of some fencers. ''I'm pretty aggressive," she
states. "I kind of overpower people. But I've been working on my defense a lot more, too."
The showing in Sydney was even more impressive
because Marsh, who had been rather busy adapting to
her new life as an intern, didn't do a great deal of train-

I

..
•
..

ing. She lifted weights, did some running and watched
videotapes of potential opponents, but there just
wasn't time to do the intensive training she's done in
past years. "Maybe my attack isn't quite as strong anymore because I haven't had time to train as I once did,
due to medical school and residency," she notes, "but I
have more strategies and more of a well-rounded game."
Once the competition was finally under
way in Sydney, however, Marsh's veteran
savvy kicked in, making the quarterfinal
match against Hungary a drama worthy
of its Olympic billing. "We were ahead
throughout the beginning of the match,"
Marsh explains. "But in the middle they had
a couple of good bouts, and they started
catching up. I was feeling like the tide was
turning and they were gaining on us. But our
comeback was really dramatic, too. Iris won
to get us back ahead, and I was last, against
Hungary's top fencer. She's really strongone of the top 10 women in the world- and

Acompetitor who is
known for her
always·attacking
style, Marsh admits
to having no patience
with the careful
parrying of some
fencers. "I'm pretty
aggressive," she
states. "I kind of
overpower people.
But I've been working
on my defense alot
more, too."

I always have trouble with her. But I just tried to focus
and not get too nervous.
"I felt a lot of pressure initially. She has some moves
that always catch me off guard, so I tried to really keep
that in mind when I was starting, and it worked for me.
I beat her S-2."
Match to the Americans.
Adding to the piquancy of the victory was the fact that
members of the Chinese and Cuban fencing teams
watched from the stands, as did Chelsea Clinton, a friend
of the Zimmerman sisters at Stanford University.
After the foil was put away, the Olympics held other
pleasures for Marsh. H er parents redeemed a slew of
frequent-flier miles to be there, and the three of them
toured the Great Barrier Reef. Also, the fencing team
CONTINUED ON

P AGE 29

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E PERSO FOLLOW ING Ann Marsh's Olympic efforts with a keen interest
was Philip B. Wels, MD '41, professor emeritus in surgery at University at Buffalo
School of Medicine and Biomedical Sciences and chair emeritus of the University
at Buffalo Council. He had good reason: An outstanding fencer in his youth, Wels
was himself once named to the U.S. Olympic team.
But fate intervened. The year was 1936,
and the Olympics were to be held in Berlin
under the oppressive sway of Adolf Hitler.
The United States boycotted the games, and
Wels' Olympic team never competed.

B

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then go to tournaments on Saturday and
Sunday," he recalls. "I was pretty serious

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"I was a very, very unorthodox fencer. I

didn ' t stick to the positions they taught me.
My style was aggressive. 1 tried to use a more decep-

Wels says that the missed opportunity was of course
disappointing, but adds that the Olympic experience in
the 1930s wasn ' t like it is now, with athletes devoting

tive type of attack than forceful. J was a bouncing
type of guy, all over the place."

years entirely to training for the Games. The main focus
then was intercollegiate competition,

years and even for a time in medical school. After

Philip I . Wels. MD '41.
professor emeritus
in surrery at the
University at luflalo
was inducted in the
Ul Athletic Hall of
Fame in 1965 for his
fencin£ prowess.

Wels pursued the sport through his undergraduate

and Wels says he has plenty of great

medical school, he served in the Army in the Pacific

memories in that arena. In college at
UB, he fenced with all three weap-

during World War ll and when he returned to UB to
complete his residency, he coached the UB team for a

ons- a rarity- and placed fourth in

couple of years, but "then just kind of faded out of it,"

the United States in foil.
Wels also notes with pride that the

he says. "It's a strenuous sport. 1n intercollegiate competitions, r fought both team and individual bouts, and

UB fencing team he founded was more

I would lose 10 pounds in two day of fencing."

successful than most of the school's

Wei 's remarkable accomplishments in this rigorous discipline were not forgotten, however, as in I 965

athletic teams, explaining that one year the wrestlers
were 0- 6 and the basketball team was 0- 13, while the
fencers went 6- 2. "I used to practice five days a week,

he became an original inductee into the UB Athletic
Hall of Fame.

Former fencer Philip Wels, 'MD 41, a knowing observer

28

about it, and it kept me in great shape.

l•flalo Hysician

Wi11t e r

2 001

�METTLE,

CONTINUED

FROM

PAGE 27

shared a house in Olympic Village with the U.S. women's
judo team, giving the athletes a chance to compare notes
on their sports. "That was a good opportunity for us; we
really enjoyed talking to them and learning about their
sport," Marsh says. "Fencing and judo are both martial
arts, so there are some interesting similarities."
Back in Buffalo after a nine-week leave of absence,
Marsh quickly settled into her medical training, refocusing her energy and talents on emergency medicine.
She recalls with enthusiasm an opportunity she had to
help treat a 19-year-old man with four bullet wounds.
"You definitely see people at their worst in the emergency room," she says. "But you have the ability to have
a big impact."
Since her return, Marsh has also been sharing the
story of her Olympic experience with others.
Her fellow residents had followed the competition closely and there's little doubt this
group of doctors-in-training knows more
about fencing than most. (Earlier in the year,
in response to numerous requests, Marsh
demonstrated the sport in a lecture hall at
Buffalo General Hospital, fencing with a
friend from Rochester. "People are always so
impressed when they see it," she says.)
But there's no fencing club in Buffalo
and little free time in the life of a medical
resident. So lately, for fun, Marsh has been playing
tennis and learning the guitar. She says she'd like to
eventually get married and have children. And she's
realistic about competing against younger, bettertrained fencers. "What I don't want to be is the older
woman who's still trying to compete at this
level," she says.
While her career as an Olympic athlete may be
behind her, Marsh can certainly look forward to taking
her gifts of agility, strength, balance and mental
dexterity into the arena of emergency medicine, where no
doubt they will serve her- and her patients- well. 4D

Wint e r

20 01

luff1l1 Pbysiciu

29

�R

E

E

A

R

C

E

H

W

Drug Delays Symptoms of Multiple Sclerosis

LAURENCEjACOBS,

30

1111111 Physic i 11

Wi11ter

2001

MD

�Medicinal
Properties of
Venom Examined

the scientists found that the 20

Biophysicists at the University

gan were more than twice as likely

at Buffa lo h ave identified a
component of venom from a

to have died during follow-up

C hilean tarantula that blocks

tion. Women in the lowest group

....

the action of ion channels re-

were more than one and a half

0

percent of men with the poorest
lung function when the study be·

than men with the best lung func-

sponsible for cellul ar mechani-

times more likely to have died.

th e

.
..

"This observation suggests

cal responses-specificall y, the
cell 's ability to feel.

that those with lower lung-

These channels or pores in
the cell

0

function levels may need to pay

membran e-called
mechanics , sa ys Frederick

acti vated ch annels also pl ay a

causes them to open and close-

Sach s, PhD, UB professor of

role in th e successful tran sition

have been implicated in func-

ph ysiology and biophysics, and

of newborns from th e placental

tions as diverse as the se nses of

senior researcher on the project.

oxygen suppl y to using their

touch and hearing, muscle con-

" For example , cells swell

traction and coordination, and

during congestive heart failure,

blood pressure regulation.
This is the first report o f a

and this peptide interferes with

own lungs."
The next re sea rch phase ,
Sachs says, will in vo lve identi -

th at process," Sachs explain s.

fying other biological actions of

substance (in this case, a small

" We al so know from earlier

protein ) that specificall y blocks

work that stretching the heart
can initiate fibrillation. If we

stretch -activated chann els. Until now, it has been difficult
to associate these channels with

can block the stretch-activated
channels, we ma y be able to

particular function s beca use

block fibrillation , a cause of

there were no chemical com-

death following heart attacks."

pound s known specificall y to

Addressi ng another area ,
Sachs notes that tumor inva-

the peptide and findin g a drug
compan y to turn th e peptide
into clinically useful drugs. 4D
- L O I S BAKER

on their lungs, " says
Holger Schiinemann,
MD, research assistant
professor in the Department of Social and Preventive Medicine, who
led the investigation.
Schiinemann

and

colleagues analyzed
data from the Buffalo
Blood Pressure/Erie

"It is important
to note that the
risk of death was
increased for
participants with
moderately
impaired lung
function, not just
those in the
lower quintile."

County Air PollutionPulmonary Function Study collected during 1960 and 1961.

Lung Function
Associated with
Longevity

The original study enrolled 2,273
women and men between the
ages of 15 and 96 from whom

How well your lungs function may

information on lifestyle factors

predict how long you live. This

and health status , including pul-

finding is the result of a nearly

monary function , was collected.

30-year follow-up study conducted

In 1990, a follow-up study deter-

by University at Buffalo research-

mined which participants had

ers on the association between

died and their cause of death.

from the Universit y of Vir-

sion of brain tissue produces a
deformation of the surrounding norm al cells, causing them

ginia, Michigan State University

to release growth fa ctors that

and NPS Ph a rma ce uticalsappears in the May 2000 issue of

may fac ilitate or accelerate tumor growth . Stretch-activated

th e ]oumal ofG eneraLPhysiology.

channels may be the signal for

impaired pulmonary function

The newl y identified peptide

no rm al cells to release growth

and all causes of mortality.

collaboration with· scientists

ative effects, such as smoking,

says. "Stretch -

cause stretching the membrane

block them .
Re sults of the research-a

particular attention to avoid neg-

tumor s," h e

stretch- activated channels be-

toxin could have several clinical

facto rs. "Th is peptide blocks

In the study, published in the

applic a tions re late d to ce ll

those channels and may aid in

September 2000 issue of Chest,

The purpose of the current
study was to investigate the

I

C O NT IN U ED

ON

PA G E 3 2

"foR EXAMPLE . CELLS SWELL DURIKG CO:SGESTIVE HEART FAILURE, A:\'D THIS PEPTIDE INTERFERES WITH THAT
PROCESS." SACHS EXPLAL'S.
F BR d
C

~SE

\T 0

. IF \1'

"V\'E \LSO K 0\1 F~0\1 EARl ER \\ORK

C \.BLOCK fHE STRE.Ct:-\Cfi\ATED C lA.

H\f STREfU l G

fHE HEARI (A

l 'lTl-\TE

ElS, \IE \1\1 BE \BLE TO BlOCK FIBRIL:..Ar"O

A \1 ]OR

OF DE \iH FOl:..0\1" (, Ht-\Rf ATTACKS.

\Vint e r

2001

l1flal1 Hysician

31

�assistant professor, and

between iron levels and risk of

Maurizio Trevisan, MD,

death from an y cause.

professor and chair, De-

....
..

public-health recommendations

Preventive Medicine;

must be based on reasonabl y solid

Brydon Grant, MD, pro-

evidence that what is being rec-

fessor of medicine and

ommended is both safe and effec-

physiology, and War-

tive," says Christopher Sempos,

ren Winkelstein, MD,

PhD, associate professor of social

formerly of UB, now
professor emeritus of

and preventive medicine and lead
author o n the stud y.

the School of Public

"Currently available data do

Health, University of
CONT I NUED

FROM

PAGE

31

Schiinemann says, noting that

"Sound clinical guidance and

partment of Social and

California-Berkeley.

not support radical changes in
dietary recommendations for

increased risk is found in per-

The National Heart, lung and

iron intake or screening b y

association between pulmonary

sons who never smoked, as well

Blood Institute and the German

ph ysician s to detect hi gh-

function

as among smokers. "The lung is

Research Foundation (DFGJ sup-

and

mortality for

periods that extended past 25

a primary defense organism

ported the study.

years, the limit of previous

against environmental toxins. It

- LO IS BAKER

studies. Schiinemann

could be that impaired pulmo-

It is surprising

and colleagues also

nary function could lead to

that this simple

wanted to determine

decreased tolerance against

measurement

for how long pulmo-

these toxins. Researchers also

has not

nary function is a sig-

gained more

nificant predictor of
mortality.

derlie an increase in oxidative

importance as a

normal levels o f serum ferritin, "
states Sempos . " Nor do th ey
support the need for large-scale,
randomized trials of dietar y

Iron, Heart Disease
Link Debunked

restriction or phlebotom y as a
means of lowering iron stores. "
There have been more than

have speculated that decreased

The que stion of wh ether too

two dozen studies conducted in

pulmonary function could un-

much iron increases the risk of
dying from heart di sease has
received another " no" an -

recent years on the association

general health-

Results showed that

stress from free radicals, and we

assessment

lung function was in

know that oxidative stress plays

tool.

fact a significant pre-

a role in the development of

dictor of mortality in

many diseases."

swer via a populationbased, long-term , fol low-up study con -

the whole group for the full 29

Schiinemann says the fact that

ducted b y Uni-

years of follow-up. "It is impor-

a relationship does exist between

versity at Buffalo

tant to note that the risk of death

lung function and risk of death

researchers.

was increased for participants

should motivate physicians to

The stud y, ap-

with moderately impaired lung

screen patients for pulmonary

pearing in the

function, not just those in the

function, even if more research is

October 2000 issue

needed to determine why. "It is

of A nnals of Epi-

lowest quintile," Schiinemann

CD

says. "This suggests that increas-

surprising that this simple mea-

demiology, found no

ed risk isn't confined to a small

surement has not gained more

a ss ociation

fraction of the population with

importance as a general health-

" high-norm al" iron stores

severely impaired lung function."

assessment tool," he notes.

and risk of death due to car-

The reasons lung function may

Also participating in the re-

predict mortality are not clear,

search were Joan Dorn, PhD,

between

diovascular disease, coronary
heart disease or heart attack, or

"RESULTS FRO\! THIS STUDY ARE CO "SISTE "T WITH OTHERS I:--; SHOWI;-.;G THAT IRO;:o.; DOES. "OT APPEAR TO PLAY
A DIRECT ROLE I;:o.; fHE DEVELOP\!E. T OF CORO. ARY HEART DISEASE . ..\10RE RESEARCH
STUDY THIS ISSUE I.' V.O\IF..· A."D \11:--;0RITIFS."

32

l1ffale

Physicin

\Vi11ter

2001

"EEDS TO BE DO;:o.;E TO

�Blood Vessels
Reflect Future
Health

Trevisan notes. "These were non-

history of myocardial infarction,

invasive, direct measurements of

was conducted by Trevisan and

vessel structure and function.

colleagues in Italy. Forty healthy

which showed positive findings,

Researchers can see the future

Our findings showed thickening

subjects between ages six and 30

Sempos notes. Still, the subject

years with a parental history of

between diseases of the heart and
circulatory system, and measures
of body iron stores, only a few of

in the blood vessels of children

in the interior layers of the

remains controversial.
The current study was based

with a parent who has had a pre-

carotid artery and a malfunction

premature heart attack were

mature heart attack, and the

of the endothelium, the lining of

compared with 40 persons with

on data collected from partici-

picture is not pretty.

the vessel. Both these abnor·

no family history of heart disease,

malities are indicators of 'pre-

matched for age and gender.

pants in the second National
Health and

'

utrition Examina-

A study published in the New

Trevisan says few stud-

England Journal of Medicine

tion Survey (NHANES II) between 1976 and 1980, and an

(Vol. 343, No. 121

ies have looked at

by University at

the association

analysis of death records through

Buffalo research-

between family

December 31 , 1992. The study

ers reports that ul-

history of heart

sample consisted of 1,604 per-

trasound images

disease and

sons-128 men and 100 black

showed structural

both

and functional ab·

vessel struc-

women; 658 white men and 718
white women- between the ages
of45 and 74.
"Results from this study are
consistent with others in showing
that iron does not appear to play a
direct role in the development of

to lead to atherosclerosis in children as young as

was already reflected in

Other researchers on the
study included Anne C. Looker,

..

results could

•

have important

'"

be further explored
so we can better under-

Trevisan, MD, senior author on

clinical disease,' disease that

the study and professor and chair

doesn't yet have symptoms."

in the Department of Social and
Preventive Medicine.

It has been known for some
time that persons with a parental

stand the causes and disease
path of coronary-heart disease
and plan early-intervention
strategies," he adds.

history of premature coronary

A team of physicians from

pants with a parent who had a

disease are themselves at high

the A. Cardarelli Hospital,

heart attack before the age of 60

risk. This research set out to

Federico II University and S.

had vessel layers that were 11

determine if it was possible to

Maria di Loreto Hospital in

Disease Control and Preven -

percent thicker and vessels that

see structural and functional

Naples, Italy; and M. Gene Bond,

tion, and Daniel L. McGee of

were 55 percent less reactive

changes in the arteries of these

director of the Division of Vascu-

Loyola University Stritch School

than blood vessels in children

persons at an early age.

lar Ultrasound Research at Wake

of Medicine.

with no parental history of heart

The study, which involved re-

Forest University Baptist Medi-

attack. "This was not a measure-

cruitment of children and young

cal Center, were major contribu-

ment of clinical disease,"

adults with and without parental

tors to this study.

Richard F. Gillum, Cuong V.
Vuong and Clifford L. johnson,
all of the

ational Center for

Health Statistics, Centers for

-LOIS BAKER

Results showed that partici·

..

tions and need to

"The parent's Ml
their kids," says Maurizio

;

clinical implica-

six years.

coronary heart disease," Sempos
needs to be done to study this issue
in women and minorities."

ture and tunction. "These

normalities known

says, adding that " more research

blood-

CD

LOI'i BAK~R

searc
1Vi11ter

2001

laflale Hysiciaa

33

�--

---- -

--- ---

---

-Mark vour calendars
"

Edmond J. Gicewicz
In nineteen hundred and fifty-six we tried to learn
to heal the sick. In the year of two thousand one
let's get together and have some fun.

Howard C. Wilinsky
Here's what your reunion chairs have to sa

The 40th reunion approaches. So much to do.
So little time. Join the celebration!

Louis J. Antonucci
let's toast the new millennium together. After

Jared C. Barlow

all, it's over one·haH a century since we gradu·

Thirty-five years-boy, have there been changes

ated. See you in Buffalo.

in all our lives. Come share and reminisce with
your old classmates. Transit Valley Country
Club, April 28, 2001.

Allen L. Goldfarb

Joel H. Paull
Thirty years is a long time. let's definitely make
sure we get together this year. We'll be in touch

Robert E. Ploss
let us all get together for our 50th and remi·

with the details.

nisce about our good years in medicine.

looking forward to renewing old friendships and
"re-living" some of our most fonnative years.
See you there!-R. Ploss

Linda Wild
Don't put off-now is the time to decide to
aHend our 25th reunion. Come back, renew old
friendships and catch up on everything new in
Buffalo and at the medical school.

II f fIll

PI J I i C iII

i~

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£11011111-' ........,. c- ..... ......
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..........

A plan for living.
Hospice really is a plan for living.
And the sooner you call, the sooner
we can help you put that plan into
action - with emotional support,
pain management, in-home care anything you need to keep
enjoying life. Call 686-8077.

T H E

CEKTE R

FOR

H1SPICE&amp;
PAlLIATIVE CARE
www.hospicebuffulo.com

ltffah Urslclu

II

�-

- -- ---

-

- -

~--

-

---

---

. - --

Dear Fellow Alumni,
Fl' \ l \K.S AGO, I \PI'ROACHI D DR. JAc K RICHFk (then- associate dean for alumni affairs ) and
asked him about my doing some work in the medical school. Jack and I had been friends for a number
of years, but even he was curious as to why I needed "another job. " He knew I was very busy with my
practice and my wife and four sons at home. I told jack that after years of being on
hospital committees and attending insurance company meetings and other medically
related events, I needed a change.
By joining the Medical Alumni Association, I felt I could learn a little about what
was going on in the school and see if I wanted to do more. Indeed, my tenure with the
Medical Alumni Association has been a very fulfilling experience.
In today's world, especially in New York, most of the medical establishments are in turmoil. It
seems almost everyone is loosing money, suing someone or is being bought and sold. There are
constantly new rules, new players and outrageous situations with which to deal.
The one constant for all UB graduates is the medical school. The Medical Alumni Association is our
fraternity; the school, our house; and all the alumni , our "brothers and sisters." Sure, the school has its
problems, but it will always be here and it is one place we are alwa ys welcome.
With various opportunities in every department, there are many avenues to develop an ongoing
relationship with our school, something we all need to do. Anyone wishing for more information, please
call the Medical Alumni Association Office at (716) 829-2778.
So, remember to support your school. join the Medical Alumni Association; become a lifetime
member.
Be healthy and happy.

jOHN

31

p~ JS i

Ci I I

1\!irrter

2 0 0 0

j .

BODKIN

II . MD
President, Medical Alumni Association

�C

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S

1950s

1960s

Robert A. Benninger, MD

Franklin Glockner, MD '60,

'50. Cape Coral, FL,

orthopaedic surgery, "I
am acting my age; no
more flying or sailing.
Assistant Pastor at Calvary Wesleyan Church."

Truno, MA, orthopaedic
surgery. "I retired as
chief of orthopaedics,
Albany, VA, 1998."
E-mail is: glockner
@medicine. net.

Alfred E. Falcone, MD '50.

Francis J. Klocke, MD '60,

Jamesville, NY, plastic
surgery, "Love you all!
Retired!" E-mail is
aefalcone@aol.com.

Chicago, IL, internal
medicine and cardiology, writes: "I work for
Northwestern University
Medical School, where I
am a professor of medicine and director of the
Feinberg Cardiov cular
Institute. My wife and I
have five children ranging from 30 to 39 years
of age." E-mail is: fklocke@northwestern.edu.

Eugene J. Zygaj, MD '50,

Lancaster, Y, OB/GY
"I play softball four
mornings a week. Our
group consists of90-!00
men over 60. Great exercise and fun."
Irving Joffe, MD '55,

Boynton Beach, FL,
radiology. "I am partially
retired, working part
time for the Palm Beach
Health Department,
State of Florida. Also
doing volunteer work
in several clinics."
John H. Paterson, MD '55,

East Aurora, NY, OBI
GYN. "I retired in 1998,
and am working part
time for a rural hospital
in Bath, NY-lowpressure position. I
have a cottage on
Keuka Lake."
Leonard R. Schaer, MD '55,

Alamo, CA. "I am retired." E-mail address is
nanapop@hotcoco.infi.net.

Pathologist Fierro, an Author's Inspiration

experiences as the chief of a Statewide Medical Examiner System, the State

factual errors. She is also the inspiration behind the fictional medic
Kay Scarpetta, characterized in many of Cromwell's books.

Andre D. Lascari, MD '60,

Poestemkill, NY, pediatric hematology/
oncology. "I retired in
Aprill999."
Lance Fogan, MD '65,

Edwin R. Lamm, MD '60,

Lakeland, FL, general
surgery, general practice,
nursing home care. "I am
vice president for Medical Affairs for Genesis
Eldercare; my wife, Rosemary, obtained a PhD
and teaches nursing. I
have certification as a
medical director from the
American Medical Directors Association and am
a member of the board of
directors for the Florida
Medical Directors Association; president, Central Florida Physicians
Alliance," E-mail is:
rslamm 1@aol.com

Valenc ia, CA, neurology,
writes: "I retired in 1997.
I'm teaching UCLA neurology residents two
months a year. I fill in
occasionally when
needed at my former
med group offices, take
classes, travel. I haven't
been bored yet!" E-mail
is: lfogan@aol.com.
Dean Orman, MD '65,

Clarence, NY, internal
medicine/ gastroen tero 1ogy, writes: "My wife,
Donna, graduated from
UB medical school in

1984 and practiced with
an HMO for II years.
Both daughters graduated from UB medical
school and are practicing pediatrics. Whitney
married a classmate,
Andrew Feinberg,
whose father and I were
also classmates (Mike
Feinberg)!"

1970s
James M. Baker, MD '70,

Poulsbo, WA, family
practice, writes: "I
worked in small towns
all these years but have
been forced financially
to join a large group
where I work less and
make more. My youngest is graduating from
college this year. My wife
and I are active in
church and enjoy the

childless phase of life."
E-mail is: baker
poulsbo@pol.net
Carl Ellison, MD '70, Tulsa,

OK, Pediatrics, writes:
"I retired from the U.S.
Public Health Service in
1998 after 21 years. I am
working for the Cherokee Nation as a primary
care pediatrician." Email is: carlellison
@gateway.net.
Alan J. Fink, MD '70,

Wilmington, DE, neurology, writes: "I am still
married to Phyllis after
31 years. Our oldest son,
Greg, is in his second
year of dental school at
the University of
Pennsylvania, and our
younger son is attending

I

CoNTINUED or.; PAGE 38

assnotes
\\'i11ter

2001

I a fla il H J Si c i I I

37

�~--

--

CLASS

COr-.iT I~ UED F RO M P AC E 37

Washington and Lee
University. " E-mail is
drafink@aol.com.
John D. Foley. MD ' 70,

El Paso, TX, pediatrics,
adolescent medicine,
writes: " I retired from
the U.S. Army with 22
years of active duty in
I 995. I am currently on
the fu ll -time faculty at
Texas Tech University
H ealth Science Center,
as an asssociate professor
of pediatrics and the
director of adolescent
medicine." E-mail
address is john52l6
@aol.com.

-

--

-----

-

---

--------

I

NOTES

Jan M. Novak. MD '70.

Williamsville, Y,
gastroenterology,
writes: "My son David is
a graduate ofUB Medical School ( 1997 ) and
son joshua is a UB
Medical Student (2003 }.
Our daughter judith is a
graduate of UB 's English
department and is now
a graduate student in
Health Care Policy at
American University in
Washington, DC. "
Hug11 A. Sampson. MD ' 75.

Larchmont, Y, pediatric allergy and Immunology, writes: " My
wife, Anne, and I have
three children, ranging

Terence Chorba, MD '79

from 13 to I 8 years of
age. I am currently a
professor of pediatrics
and biomedical sciences, the chief of

ICEP Leaders~ip Award

pediatric allergy and
immunology, the Kurt
Hirshhorn Chair in
pediatrics and the director of General Clin ical
Research Center at
Mount Sinai School of
Medicine." E-mail is:
hasampson @aol.com.

1980s
Christopher S. Walsh. MD

'85. medical director of
the Cancer Center of
Virginia, in Fredericksburg, VA, has developed

studying the association
between HIV and other
opportunistic illnesses.

Terence Chorba, MD

national Center for HIV,

The Project is based in

' 79, writes: "Over the

STD, and TB Prevention.

the Infectious Diseases

years, I have had an

Project Retro-CI is an

Ward of the Centre

enjoyable career in the

epidemiologic, labora·

Hospitalier Universitaire

U.S. Public Health Ser·

tory and clinical

de Treichville, the larg-

vice with several unique

research collaboration

est public hospital in

assignments. We used

between the Ministry of

Abidjan, and currently

to live in Kazakhstan,

Health (MOH) of Cote

has a full-time staff of

where I started an office

d' lvoire, the Institute of

140 persons. My wife,

for the U.S. Centers for

Tropical Medicine in

Lindy, is a nurse practi·

Disease Control and Pre-

Antwerp, and CDC . It

tioner working at the

vention (CDC) to address

serves as CDC's primary

U.S. Embassy. Our three

infectious disease issues

research center for the

children are busy learn-

in all five Central Asian

study of HIV infection in

ing French and are pa-

Republics of the former

Africa. The work is fo·

tient with our efforts to

Soviet Union. Currently,

cused on preventing HIV

keep up their Russian. If

we live in Abidjan, Cote

in uninfected persons;

any classmates come to

d' lvoire, where I direct

preventing HIV disease in

West Africa, I would be

Project Retro-CI on

persons already infected

glad to meet them and

assignment from the

with HIV; assisting the

reminisce about old

International Activities

MOH in monitoring the

times." E-mail address is

Branch of CDC's

HIV/AIDS epidemic; and

chorba457@hotmail.com.

the VEEBAAT TM System, which debuted at
the American Society
for Therapeutic Radiology and Oncology 2000
exposition (ASTRO
2000 } in Boston , MA,
on October 22-25, 2000 .
VEEBAAT-which is an
acronym for Verify
Event Entries Before
and After Task-is a
new electronic decision

support system designed
to he lp reduce the risk
of error in the radiation
oncology treatment process. Walsh developed
the system because he
found that the new sophisticated digital technologies susbstantial ly
improved automation,
but none maintained
the human cross-check
process in a manner

�that enabled efficient
manual recovery to safe
mode of operation, or
what he calls "Symmetric Recovery TM." For
more information on
the new system, go to
www.veebaat.com, or
call VEEBAA T Medical
Technologies, Inc., at
(540) 785-4488.
Michael Rokaw, MD '88,

writes: "I'm in private
practice nephrology in
Shreveport, LA. I' m enjoying the change from
academic medicine.
While at the University

of Pittsburgh, I received
a National Kidney
Foundation Young
Investigator grant, a
Paul Teschan DC!
research grant and a
National Institutes of
Health First Award for
sodium channel
regulation. I authored
seven papers and over
20 abstracts. My daughter, Sarah, is four years
old (in K4) and enjoys
swim class, dance class
and gymnastics. My
wife, Amy (we
celebrated our ninth
anniversary in April

2000) and I are loving
southern living. Miss
my classmates, and
think of them often."

E-mai

1990s
Joseph Accurso, MD '92,

writes: "! completed a
five-year radiology/
nuclear medicine
residency at UB after
my three years in the
U.S. avy. I spent one
year in Antarctica,
providing medical care
to the U.S. researchers.
I have been married for
almost five years (no

children yet) and am
now with the Mayo
Health System at the
Austin Medical Center
in Austin, M . E-mail
address is: accurso.
joseph@mayo.edu.
Cynthia L. Jenson, MD '92,

writes from Bangor,
ME: ''I'm in my second

year of private practice
in anesthesiology. We
are finally settled after
a long first year.
Alexandra is five and a
half and is in kindergarten, and Erica is two
and a half. Mark is staying home and loving it."
E-mail address is:
cjenson@prodigy.net

Henry V. Morelewlcz, MD '38
champion of children with dl-bUity

\V in t er

200 1

1 111111 Pbpiciaa

�Eugene M. Farber, MD '43,
Internationally known dermatologist
Arthur .,J. Schaefer, MD '47,
pioneer In oculoplastlc surgery

1111111 npiciu

\\ ' ~J

te

r

2 00 I

�- Based on FIM " Data

drill

ttTheywere
sergeantsand cheerleaders.''
-Frank Stelarski, stroke rehab patient, Harris Hill H.C.F

Why do our patients have better rehab resutts compared to the national average? Maybe it's our staff
''They knew exactly how far to push me.'' says Frank Stelarski. ''But they also encouraged me every little
step of the way. When you've been through what I have, that really means a

THE

lot." To leam more about the nationally recognized McGuire Rehabilitation

~cJNn~l(91'{_
CENTE~

Centers, call 1-888-POSTACUTE or visit www.mcguire-group.com.

* *"
AUTUMN VIEW

•

GARDEN

GATE

•

HARRIS

HILL

\\ ' 1 11 1 c

•

r 200 I

NORTH

GATE

I I I I I I I Pb J s i c i 1 n

4

~

�p H A R M

A

c

0

p

0

E I A

UB s !IJSfORY
0~ \IEDIC.INE

COILECTIO"&lt; PRF~L·rs
I'I!ARMACOPOEI \

Digitally reproduced
prints from a pharmacopoeia by Otto Karl
Bei·g (I8IS· 1866) were
on display last fall in
University at Buffalo's
Health SCiences Librai)'
(HSL), South Campus.
The botamcal show
"as developed by the

HSL and the umversity's
i \1edia staff and is the
fir;t

in

a

senes

of

"Art in the Libi·ary"
exhibits intended to
promote the History of
\1edicine

Collection

through the display and
sale of reproductions of
selected works.
Fred Kwiecien and
Don Tramoi· of i\1edia
prepared

the

prints

from the original art in
the Berg volume. pub lished 1n Leipzig 111

1863. Pictured is Picea
excel sa.

H P OliO\ 0 I

�</text>
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                    <text>�l1ffale ••ysicial
ASSOCIATE VICE PRESIDENT FOR
UNIVERSITY COMMUNICATIONS

D r. Ca ro le Sm ith Petro
DIRECTOR OF PERIODICALS

S ue Wuetcher

Dear Alumni and Friends,

EDITOR

S tephanie A. Unger
ART D I RECTOR/DESIGNER

we anxiously await word from Punxatawney Phil and
Dunkirk Dave, those furry little rodents who allegedly predict the end of wintry weather.
eedless to say, they had differing messages this year (Phil saw his shadow, Dave did not),

Alan f. Kegler
CONTRIBUTING WRITER

Lois Baker

so apparently we now have a choice as to whom we believe. Fortunately, for those on the
Campaign Committee, the Dean's Advisory Committee and/or the National Advisory

PRODUCTION COORDINATOR

Cyn thia Todd-Flick

Group, it really didn't matter, as an early February "taste of spring" was experienced in
Hilton Head, NC, where we held the annual "winter outing" for these dedicated volunteer
groups. The meeting was hosted by Linda and AI Rekate, MD '40, and by Roger Farber

UN I VERSITY AT BuFFALO. THE
STATE UNIVERSITY OF NEW
YORK. SCHOOL OF MEDICINE

who, although not a UB alum, has strong family ties to this medical school. Twenty-one of

AND BIOMEDICAL SCIENCES

these committee/group members attended and a good deal of work was accomplished.

Dr. j ohn W right, Dean

After much discussion and reflection, the Buffalo Medical-Dental

EDITORIAL B OARD

Consortium voted to discontinue participation in the "Demonstration
Project," a six-year resident-reduction program that was beginning to adversely affect the region's postgraduate educational experience. This action
averted the need to reduce the resident quota to final-year levels and
provided some needed flexibility to expand the pool, just a bit. The physician work force dynamics have changed dramatically since the Demonstration Project began in 1996, at which time a significant excess of
specialists (by the end of the century) had been predicted. The Western

ew York region

Dr. Bertram Partin, Chair
Dr. john Bodkin
Dr. Martin Brech e r
Dr. Haro ld Brody
Dr. Linda f. Corder
Dr. Alan f. D rinnan
Dr. j a m es Ka nski
Dr. Eliz abeth Olmsted
Dr. Step /1 e11 Spaulding
Dr. Bradley T. Trua x
Dr. Franklin Zeplowitz

(indeed, the entire country) is now experiencing significant shortages of anesthesiologists,
radiologists, and medical oncologists, to name just a few of the specialty areas in short
supply. We will continue our commitment to train physicians in the primary care disciplines but this action will allow us to more accurately respond to the real world's needs. A
major financial benefit to our ailing hospital systems was yet another reason for with drawing from the project.
On February 14, the Hauptman Woodward Institute (HW!) and the university announced an agreement to create a new Structural Biology Department within the
School of Medicine and Biomedical Sciences, to be housed within HWI on High Street
(see article on page 10). This formalizes the extensive collaboration that has evolved with
HWI and Roswell Park (RPC!), and will facilitate even greater collaboration in the future. Indeed, our closer relationships with HWI and RPCI have enabled us to apply for
significant new grant funding that would have been well beyond our reach had these
collaborative interactions not been in place. This development also marks an important

TEACHING HOSP ITALS

Erie Co unty Medical Cen ter
Roswell Park Cancer Institu te
Ve terans Affairs W estern
New Yo rk H ealth care System
KALEIDA H EALTH:

The Buffalo General H osp ita l
The Cl1ildren 's Hospital of Buffa lo
Millard Fillmore Gates Hosp ital
Millard Fillm ore Suburban H ospital
CATHOLIC H EALT H SYSTEM:

M ercy H ealt /1 System
Sisters of Charity Hospital
N iagara Falls M em orial
Med ical Ce nter
@

UNIYEISITY IT 18fllll.
THE SUTE UNIVEISIJT IF NEW YOlK

step to developing the Buffalo-Niagara-High Street Medical campus, an idea that holds
great promise for this community. The return of at least a portion of the medical school to
High Street should engender a bit of nostalgia for some of our more "chronologicallyadvantaged" alumni. Although the planning process has generated predictable pockets
of opposition and controversy, strong community support and visions of opportunity
abound-not an unfamiliar path to progress here on the Niagara Frontier.

---7

~MD

Dean, Schoo l of Medicine and Biomedical Sciences

Letters to the Editor
Buffalo Physicim1 is published quarterly
by the University at Buffalo School of
Medicine and Biomedical Sciences in
cooperation with the Office of
Communications.
Letters to the Editor are welcome
and can be sent c/o Buffalo Physician,
330 Crofts Hall, University at Buffalo,
Buffalo, NY 14260; or via e-mail to
bp-notes@buffalo.edu.
The staff reserves the right to edit all
submissions for length and clarity.

%

University at auffalo k
The State Ut~iversity ofNew Yor

�VOLUME

35,

NUMBER @

Features

4

Medicine Goes Molecular
New fields of proteomics and
bioinformatics are spurring
multidisciplinary research
collaborations in Buffalo
BY

S . A.

UNGER, ELLEN GOLDBAUM

AND LOIS BAKER
PHOTOGRAPHY BY FRANK MILLER

12

McKinley's Assassination
Surgeon and historian Jack
Fisher, MD '62, revisits the
the medical controversy
one hundred years later

The Temple of Musicat the 1901 Pan-American Exposition. here pictured at night. was the site of the
assassination of President William McKinley inBuffalo, New York.

DEPICTS A THREE-DIMENSIONAL STRUCTURE OF MEMBERS OF
THE SHORT-CHAIN OEHYDROCENASEIREDUCTASE FAMILY, DETERMINED AT

THE HAUPTMAN-WOODWARD MEDICAL RESEARCH INSTITUTE. WORK ON
THE STRUCTURE RELATES TO BREAST CANCER AND THE SEARCH FOR MORE
EFFECTIVE DRUGS TO TREAT THE DISEASE.

18 John Naughton,
honored by
AMS of ew
York for
distinguished
service

22 jacobs study
named Top 10
for 2000
by Harvard
Health Letter

18 Paola Muti
Emeritus
Faculty Group
formed

27 Robert Blake
Reeves and
james E. Allen
remembered

named first
chair in
family medicine
at Tuft's
University

23 jerome Kassirer
honored by
American jewish
Congress

studies breast
cancer and the
role of
hormones
and insulin

32 Cocaine use
and heart
attacks

33 Marjuana use
and male
infertility

34 Message from
the director"Every Gift
Vital to
School's
Future"

35 james Platt
White Society

37 Edmund Hayes
Society

40 ews from
your UB
classmates and
other alumni

44 Eugene
Morhous and
George Alex
Poda
remembered

�-

Internal Medicine's Man

T

hank you for the wonderful article
on James Nolan, MD, in the autumn
2000 issue of Buffalo Physician. He was
an outstanding role model in internal
medicine, and I am one of the legions
of medical students who followed his
lead into academic medicine. It has been a source of
pride to watch his leadership of the American College of Physicians and his
support of training of
more generalists.
Finally, during the time
I was a minority student in
Buffalo in the early 1980s,
Dr. Nolan helped to shape a
demanding yet inclusive
and supportive environment m which
excellence was expected. To me, this will
be his greatest legacy.

0

-

W

hile scanning through the newly
arrived autumn 2000 issue of
Buffalo Physician, I discovered a wonderful
group photo on page seven. In it are pictured the Internal Medicine House Staff,
1967, of the Buffalo General Hospital.
I think the photo is wonderful because it shows
Helmut G. Schrott, MD '66,
my husband, in the first
row, far right. However, he
is identified as "Harold
Schrott," an understandable mistake because everyone called him "Hal," but
incorrect nevertheless. If
you look in your database, I
think you will find that he
has long been a professor of internal
medicine at the University of Iowa Hospitals and Clinics in Iowa City, Iowa.

Sincerely,
DavidS. Kountz, MD '85, FACP

.+-J

Mara J. Schrott

Associate Dean for Postgraduate Education
Associate Professor of Medicine
Chief, Division of Primary Care
UMDN]-Robert Wood Johnson
Medical School

I

just wanted to let you know how
wonderful your article on Dr. Nolan
was. It was quite a tribute to a man who
had an exemplary career. I remember
Dr.
olan as being an exceptional
teacher and legendary clinician. Your
superb article certainly brought that out.
Congratulations on writing a real "gem."

Stephen Lazoritz, MD '76

Vice President, Medical Affairs, Children's
Hospital of Omaha

I

always enjoy reading Buffalo Physician
and thought your article about Jim
Nolan was very good, but I think you
could have done better at identifying the
people in the '67 photograph [of the internal medicine house staff]. The two women
in the picture are myself-Carol Segal (not
Siegel), the third from the left, front rowand Marie (Tony) Verso; I do not see
Daphne [Hare] at all. Behind Tony on the
end of the second row is Ron Rohe, who
became chief resident after Bill [Fleming].
Kenneth Newmark is third from the left
in that row. Bob Moskowitz is third &amp;om
the right, front row. Joel Schnure is the
correct spelling for the resident between
Dr. Calkins and Bob. Lou Wertalik is in
the back row.

Sincerely,
Carol Segal, MD

2

luffalo Physician

Spring

2001

~---

�tion (successfully) at the Buffalo General
Hospital.
As far as I know, the mentoring program
was accepted and carried on then for
some time in the '50s. From the Buffalo
Physician article, I gather that it fell on
hard times and then was renewed and now
apparently funding is being withdrawn
from some other sources.

I

n regard to the unknown individuals in
the photograph [of the internal medicine house staff] on page 7 in the autumn
2000 issue of Buffalo Physician, I believe I
can identify the following:
1. SAMUEL ARMSTRONG

2. ORMA BERKOWITZ
3. ARTHUR COHEN
4. DAVID DANTZKER
5. DouGLAS GERSTEIN
6. LIBERATO !ANNO E
7. Ro ALD JosEPHSON
8. JOHN MENCH! I
9. DONALD MILLER
10.

DouGLAS RosiNG

11.

BRIA

12.

JAMES STROSBERG

13.

CALVIN TREGER

14.

LOUIS W ERTALIK

SHEEDY

Sincerely yours,
Douglas Gerstein, MD

San Rafael, CA

Primary Care Summer
Externship Program

I

read with interest the article by Debra
Stamm in the winter 2001 issue concerning the Primary Care Summer
Externship Program ... and I thought
you might be interested in the following
story of my involvement in primary care
training for Buffalo physicians.
In the spring of 1950, I approached
Dean Stockton Kimball to request that I
be allowed to spend time in my junior/

Internal Medicine House Staff, 1967

senior year with a general practitioner,
literally living with him or her and observing the practice of medicine and patient
care at the level of a capable general practitioner. If I could spend my summer this
way, I promised to report to Dean Kimball on my experiences and then, if approved by the faculty, the program could
be offered to subsequent classes as an
elective. Dean Kimball agreed and with
the help of other faculty found a doctor
in East Aurora, Dr. Donald E. Donovan,
who was willing to be my summer mentor.
I spent a fascinating month with
Dr. Donovan, living at his home and
answering all calls, seeing patients in his
office and studying up on the subjects
his patients called to my attention.
During that time, I helped diagnose a
coarctation of the aorta of one patient
and helped to arrange for Dr. John
Payne to correct that congenital condi-

It is interesting how the direct care of
patients has suffered in these modern
times. The economics of medical care have
been the most important factor, as well as
the variable "prestige" of specialties. I
guess "follow the money" is the American
way of life, but there will always be a few
romantic and selfless people who want to
deal directly with patients' problems and
ills. Thanks be for this.

Sincerely,
Robert E. Ploss, MD '51

Letters to the Editor

are
welcome and can be sent via e-mail
to bp-notes@buffalo.edu; or by post
to Buffalo Physician, 330 Crofts Hall,
University at Buffalo, Buffalo, NY,
14260. Letters may be edited for
length and clarity.

Spring

200/

lu flllo Physicin

3

�A&lt;; r YtAR ABOl T Tills TI~

the biomedical community was

abuzz with news that the much-vaunted Human Genome

By S.A. Unger
nd Ellen Goldbaum

Project was coming to a climax as rival international groups, both private and
government-sponsored, raced toward the finish line in what is arguably one of the
most important accomplishments of the 20th century.
But what does it mean now that we have sequenced the full complement of DNA
in the human genome, and how can these data help scientists develop advanced
medical treatments? Much like when a sculptor unveils his prize work of art only to be met
with a quizzical, "What is it?" scientists today are now busy explaining to a highly expectant
public why the Human Genome Project is indeed a masterpiece.
In essence, what they are telling us is that although the Human Genome Project was a
Photos By
Frank Miller

.t

luffalo Phys ici aa

"race," it was more specifically, a relay race-and only the first leg of it
has been run.

Spring

2001

�PROTEOMICS

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The baton-the decoded human genome-is today being

.

•

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.c

"

handed off to a new set of sprinters who will take it a second lap,
bringing scientists just one step closer to what most nonscientists
consider the "real" finish line: the translation of basic science into
clinical science, where it has practical applications for patients.
This second lap in the relay race is today being referred to as
the "post-genomic era" because scientists running it are no
longer focused on mapping and sequencing genes; instead
they have turned their attention to the substances genes
produce: proteins.

E
.
.

..•

xperts now estimate that we humans have some 30,000
genes that are responsible for churning out thousands of
different proteins. The challenge is that, in most cases, the
functiOn of these genes and their proteins is a mystery.
Toward the goal of unlocking the secrets of proteins, a
new scientific field called proteomics has sprung into being, the aim
of which is to discover the structure and interactions of all proteins
in a given cell. By studying the proteomic landscape of healthy and
diseased cells, researchers may better understand the complex ways
in which cells communicate at a molecular level, which in turn can
lead to a better understanding of our body's metabolic pathways.
Once these mysteries are deduced, pharmaceutical companies
can collaborate with basic scientists to develop more sophisticated
diagnostic devices, as well as new drug targets. In this new world of
pharmacogenetics and pharmacodynamics, scientists will attempt
to identify which misguided protein needs targeting and design

BIOINFORMATICS

drugs that bind to it in order to turn it on or off-a form of
treatment that, because of its specificity, is predicted to produce
few, if any, side effects.
Although scientists do not know the details surrounding how
proteins function, what they do understand is that a protein's
function is often tied to a protein's shape; in other words, the way
in which a protein interacts with other molecules is in many cases
determined by its three-dimensional architecture.
In this post-genomic era, therefore, much attention and
tremendous resources are being marshaled toward the goal of
modeling the three-dimensional structure of as many proteins
as possible. More specifically, scientists who have expertise in
structural biology are seeking to devise ways to better understand, and even predict, how a gene's D A directs amino acids
to fold in order to create a protein's three-dimensional shape.
(Based on current knowledge, scientists estimate that there are
several thousand different classes of protein folds.)
The quest to sequence proteins and model their shape
promises to be as thrilling a race as was the one run to decode the
human genome.
Over the past few decades, scientists have devised a number of
laboriously painstaking techniques to determine the shape of a
protein. One of these techniques is crystallography, which involves bombarding single crystals of protein molecules with X-ray
beams. The beams are diffracted by the atoms of the protein molecule thereby generating the diffraction pattern. This pattern is
then analyzed by computer to define the protein's molecular

Spring

2001

lulfale Physician

5

�-~

PROTEOMICS

AND

structure. A second technique involves nuclear magnetic resonance (NMR) spectroscopy, which uses powerful magnets to
determine the chemical shifts of nearly all atoms of the protein.
Knowledge of these shifts enables scientists to measure distances
between protons, from which protein structure can be calculated.
·ke the Human Genome Project, the success of proteomics
ill depend heavily on the ability of scientists to automate
[
nd greatly accelerate these and other protein-modeling
techniques-as well as protein-sequencing techniquesin order to process phenomenal amounts of information embedded within all the proteins in a given species, or its
proteome. Integral to this automation effort will be the tandem
development of new generations of supercomputers and
robotics systems.
Underpinning this entire post-genomic quest is the burgeoning new field of bioinformatics, where computer scientists and
biologists work side by side toward the goal of harvesting information produced by the genome and proteome projects in order
to provide medical researchers with the knowledge they will need
to move forward with discoveries.

Center of Excellence in Bioinformatics
It was with an understandable sense of pride and accomplishment,
therefore, that the University at Buffalo learned in January 200 l that
New York State Governor George Pataki, in his "State of the State"
address, proposed that Buffalo be designated as the site for a worldclass Center of Excellence in Bioinformatics.

6

lu llale Ph ysician

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-

-

--

BIOINFORMATICS

In what Bruce Holm, PhD, senior associate dean in UB's School
of Medicine and Biomedical Sciences, describes as "one of the biggest announcements made at this university in at least a decade,"
the governor detailed plans for the center, which he said would be
one of three established across the state as part of an ambitious
$1 billion high-technology and biotechnology plan aimed at positioning ew York State as a worldwide leader in university-based
research, job creation and job development.
The other two centers- one of which
would be located in
Albany for nanoelec-

I

...

Scientists who HAVE EXPERTISE
I • STRUCTURAL BIOLOGY ARE SEEKI:-;'G

tronics, and the other
TO DEVISE WAYS TO BETTER U . DERSTAND,
in Rochester for photonics and optoelec- AND EVE •• PREDICT, HOW A GENE's
tronics-would, along
DNA DIRECTS AMINO ACIDS TO FOLD IN
with the Center of
Bioinformatics, serve ORDER TO CREATE A PROTEIN's THREEto link university reDIMENSIONAL SHAPE.
searchers directly with
private industry as
part of what Pataki referred to as "the largest high-tech economic
development initiative in our state's history."
Making Buffalo a dedicated research site for bioinformatics is a
natural progression of the pioneering work that the proposed
center's three partner institutions-University at Buffalo, Roswell
Park Cancer Institute (RPCI) and Hauptman-Woodward Medical
Research Institute (HWI)-have been doing for years. Holm,

�PROTEOMICS

.
.
c

AND

who points out that the majority of the DNA used in the Human
Genome Project came from volunteers in Western ew York,
courtesy of Roswell Park Cancer Institute's proficiency in creating
D A libraries, says Buffalo is uniquely positioned to make a
Center of Excellence in Bioinformatics possible because the
scientific areas in which it excels will be critical ingredients in the
bioinformatics revolution.
These ingredients, as outlined by Holm and others who will be
involved in the center, include the following:

·Supercomputing. UB's Center for Computational Research (CCR),
which is one of the world's leading academic high-performance
computing sites, has the large-scale computing and visualization
capabilities and the staff expertise necessary for tackling the massive
computational problems presented by the data in the human
genome. CCR already serves as the computational backbone for
research under a $25 million National Institutes of Health (NIH)
grant in structural genomics awarded to a consortium of nine
institutions, including UB and HWJ (see article on page 9).
"CCR provides the computing power that is essential for any
successful bioinformatics initiative," says Holm. "Without it, we
wouldn't even be in the game."
"Proteomics and structural biology require massive supercomputing capabilities," says Jaylan Turkkan, PhD, UB vice
president for research. "There are tens of thousands of different
ways that proteins can fold, so only with high-end computing
are scientists going to be able to model and predict what those
folds are going to look like."

8IOINFORMATICS

·Structural Biology, Genomics and Proteomics. Over the past five years,
more than $17 million in key scientific awards has been received by
UB's School of Medicine and Biomedical Sciences, RPCJ and HWJ
to study genomics, proteomics, structural biology and neuroimaging as they pertain to disease modeling and drug discovery.

·Generation of DNA Microarrays. The DNA microarray facility, jointly
operated by UB and RPCI, allows scientists to detect thousands of
genes simultaneously and analyze their expression. By creating custom gene "chips," each of which can contain thousands of genes, the
facility is a boon to researchers investigating which of the 30,000
human genes are active in a given cell or tissue.

·Pharmaceutical Science. Pioneering work in UB's School of Pharmacy
and Pharmaceutical Sciences led to the development of the field of
pharmacodynamics, and continued work by the same researchers
has resulted in new techniques to find markers of pharmacological
effect that can be used to optimize new drugs and therapies.

A

t the same time, HWI and UB are home to the developers
of SnB, the molecular structure-determination software
based on the algorithm developed by Nobel laureate
Herbert Hauptman, PhD, UB Distinguished Professor
and president ofHWI, and the Shake-and-Bake algorithm
developed by George DeTitta, PhD, professor and chair of the
Department of Structural Biology in UB's School of Medicine
and Biomedical Sciences and HWI executive director; Charles
Weeks, PhD, senior research scientist at HWI; and Russ

Spring

200/

l a lla l o Ph ysici an

7

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PROTEOMICS

I

.
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AND

Miller, PhD, director of CCR and professor of computer science
and engineering. SnB is the structure-determination software of
choice in more than 500 laboratories across the United States.

s za on Also at UB is the New York State Center for Engineering Design and Industrial Innovation ( YSCEDII), which has the
virtual-reality capabilities to allow scientists to visualize and interact with three-dimensional molecular structures in large, immersive environments.
The current arrangement at YSCEDII allows scientists to interact with biological data through visual data-mining techniques.
Planned expansion to a fully developed, six-wall (walls, floor and
ceiling) "cave"-a capability now available at only one other institution in the nation-will amplify the amount of information that can
be displayed by a factor of six at the very least. This new environment
will make it possible to 'walk through' a compound, evaluate the fit
of a series of drug leads to a particular target protein and suggest
changes to drug candidates to maximize their potential efficacy.

eR

Co ec on

We have the right collection of institutions, individuals and facilities
to make this [center] happen," says CCR's Miller. "In fact, many of
us have been working collaboratively for years."
And while it is very early, the business community is already
starting to respond. A major firm with strong ties to the area and an
interest in bioinformatics has stated that it is considering an additional
significant investment in resources in Buffalo, now that a Center of
Excellence in Bioinformatics has been proposed.

8

luffa le Physici11

Spring

2001

·· - - -

BIOINFORMATICS

olm adds that because Buffalo is a very low-overhead
place to locate a business, he expects to see more firms
become interested in the area as the center gets going .
"Heads are turned by this kind of investment," he says.
That's also likely to be the response from federal
funding agencies, according to Turkkan. "The federal government
wants to see that a state supports a university's activities," she says.
"When we can show them that we already have a coherent plan for
this center, that we have space identified and major support from
Albany, all of these things will make us that much more competitive,
especially because they demonstrate to the IH that recruitment
of top faculty will be much easier," she adds.
In addition, Turkkan notes, the participating institutions have
long histories of collaboration that include formal memoranda
and faculty with joint appointments, and she emphasizes that it is
the nature of those institutions themselves and the capabilities
they posses that also make it possible to exploit bioinformatics in
its broadest sense.
All over the university, and in labs throughout the world,
therefore, bioinformatics is driving such collaborations. Buffalo
already is making and exploiting those connections, but it is Pataki's
announcement that will put the area on the map.
"It's time to recognize that Buffalo has some unique strengths,"
says Holm. "The money for the new Center of Excellence in
Bioinformatics will allow us to take those strengths and turn
them into an economic engine for this area."

- --

�P

ROTE

OMI

CS

A

N

D

BI

O

I

NFO

RMATI

CS

ctures
-Woodward

resonance ( MR) spectros-

Medical Research Institute

copy to determine protein

(HWI) and University at

structures.Knowingthemo-

Buffalo have received grants

lecular structure of proteins

totaling $3.13 million to develop new, highB
speed methods to determine

is essential for designing new
drugs to treat, prevent

L o

the molecular structure of proteins. The funding is part of a

y

B

A

$25 million center grant awarded to the
Northeast Structural Genomics ( ESG)

I
K

z:

0

....
.

and cure diseases.
George DeTitta,

S
E

....
..
....

R

~

professor and chair of

the Department of Structural Biology in UB's School

Consortium composed of researchers

of Medicine and Biomedical

from UB, HWI, Cornell University,

Sciences and HWI executive

.
...•
•
...•..

Columbia University, Yale University,

director and CEO, and Jo-

University of Toronto, Ontario Cancer

seph Luft, HWI senior re-

Institute, Pacific Northwest National
Laboratories and Rutgers University,

search scientist, will receive
$1.75 million over the next

home to the principal investigator on

five years for their work in crystal-

will receive $1.38 million for research

the project, Gaetano T. Montelione.

growth methods and techniques. The
institute will use a newly developed,

using NMR spectroscopy to establish

The consortium was established in

E

protein structures. Approximately $1

response to the National Institutes of

high-throughput robotics laboratory

million was awarded through the

Health's (NIH) Protein Structure Ini-

center grant for the UB work, with the

ational

that will allow researchers to obtain
crystals for X-ray structural analysis for

additional $385,000 contributed by

Institute of General Medical Sciences

a large number of different proteins in a

the National Science Foundation.

(NIGMS). The initiative aims to capital-

short time. The new laboratory was es-

"The center grant supports the pur-

tiative, funded through the

IH

ize on discoveries generated by the

tablished with funds from the John R.

chase of a cryogenic NMR probe, which

Human Genome Project.

Oishei Foundation, making Hauptman-

The ESG Consortium is one of seven pilot research centers in structural

Woodward scientists among the first to
use this method of crystal production.

will increase the sensitivity of our spectrometer by a factor of three or more, thus
reducing measurement time of molecular

genomics, a new field dedicated to

"It is projects like these that exem-

determining gene function by defining

plify how critical initial support can be,"

the protein structure encoded in a
gene's DNA sequence. The goal of the
NIH initiative is to target proteins from
various model organisms, including the
fruit fly, yeast, roundworm and certain
human proteins.
The consortium will use both X-ray
crystallography and nuclear magnetic

DeTitta says. "The funding from the
Oishei Foundation provided the infrastructure for the lab and also gave us
another great opportunity to work with
talented colleagues, including Tom
Szyperski at the University at Buffalo."
Thomas Szyperski, PhD, UB associate professor of chemistry, and his team

structures about tenfold," Szyperski says.
"This will enable us to solve protein structures by MR in an unprecedented rapid
fashion. Such investments ensure that
our research group, and thus UB's highfield NMR center, will successfully participate in the leading-edge endeavor of
structural genomics, which will contribute to lay the foundations of this century's biomedical research," he says.

Spri11g

200 1

4D

Buffalo Physician

9

�PROTEOMI

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AND

8IOINFORMATICS

New Structural Biolo
Department Crea ed
Univers i ty at Buffalo and Hauptman-Woodward Institute to Collaborate

University at Buffalo and HauptmanWoodward Medical
Research Institute
(HWI) have agreed
to establish a UB De-

tutions for groundB
breaking research in
I. 0
structural biology and
enables UB's students
to have a unique educational opportunity to study
both at the research institute
and university," said Greiner
when the agreement was signed.
"It's a win-win situation, not
only for UB and HauptmanWoodward, but also for Western
New York because the region is
now positioned to become a
leader in this exciting field," he
added. "We're looking
forward to a long and
fruitful collaboration

partment of Structural Biology
at HWI, initiating a 10-year
collaboration that positions
Buffalo to play a lead role in this
critical field.
Under the agreement, which
was formally signed by Christopher T. Greene, chair of the
HWI board of directors, and
William R. Greiner, president of
UB, on February 14, 2001, HWI
will remain an independent entity and will continue to conduct with the Hauptmanits own research outside of Woodward Medical
projects undertaken by UB de- Research Institute."
"It is extremely repartmental faculty members.
The new department will be a warding to have been a
unit of the UB School of Medi- part of this developing
cine and Biomedical Sciences, collaboration," said
and Herbert A. Hauptman, PhD, Greene. "This new
HWI president and 1985 Nobel department will not
laureate in chemistry, joins the only allow Hauptmandepartment as a distinguished Woodward to conprofessor. George T. DeTitta, tinue its rapid growth,
PhD, HWI executive director but also adds a new
and chief operating officer, is teaching element to the
department chair and professor. Main and High Street
In addition, 15 other HWI re- medical corridor. It's
searchers assume faculty posi- positive for us, the university, the medical
tions in the department.
" This agreement brings corridor and all of
together two outstanding insti- Western ew York."

10

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2001

In his comments, Hauptman noted that "with
l ~
Hauptman- Woodward
involved with some of
the world's leading scientists in crystallography and
structural biology, this new department will provide a unique
opportunity for students to
learn and train in two different
research environments-both
an independent research institute and a university setting.
"It will allow our scientists to
mentor graduate students and

v

teach them our methods, spurring a greater interest in our
work and facilitating the development of new relationships.
"It also will encourage the
breaking down of walls, which
all too often isolate individuals
and groups from one another,
thus making the diffusion of
ideas more difficult. These ideas
are needed to stimulate creativity in the individual scientist. Without the combined
strengths of the university and
Hauptman- Woodward, this

Left to right: Christopher Greene, chair of the board at Hauptman· Woodward Medical Research
Institute (HWI), George T. DeTitta, professor and chair of the Department of Structural Biology
at the University at Buffalo and executive director and chief operating officer of HWI, and
Herbert Hauptman, PhD, UB Distinguished Professor and president of HWI.

�PROTEOMICS

AND

8IOINFORMATICS

experience would not be pos-

expertise in its midst. "This ini-

capabilities, as well as its exper-

South Campus to complement

sible," Hauptman added.
John R. Wright, MD, dean of

tiative is also a key element of
the larger bioinformatics initia-

tise in biology, biochemistry
and biophysics.

HWJ's facilities.
The agreement calls for UB to

the School of Medicine and Bio-

tive that will help to drive the

UB and HWI are already

staff the new department imme-

medical Sciences, said the new

future of the Western New York

working closely as members of diately with a minimum of four

Department of Structural Biol-

economy," he stressed.

the recently formed

ortheast

full-time-equivalent faculty

ogy "will strengthen professional interactions that already exist

The field of structural biology
dates to the 1930s, when scien-

Structural Genomics (NESG)
Consortium, a collaboration

positions. Two of those positions will be filled by six current

and greatly expand the opportu-

tists discovered it was possible to

that has resulted in a total of HWI research scientists and by

nities for future collaboration.

crystallize proteins and view

$3.1 million in grants to scien-

them in three dimensions.

tists at the two institutions for

hired to work exclusively in the

obel

genomics research. With fund-

department. UB and HWI cur-

prize for an innovative mathe-

ing from the John R. Oishei

rently are recruiting those faculty members.
The faculty members

"In many respects, the science at Hauptman-Woodward

Hauptman received a

and at the medical school is
complementary and this

two new faculty members to be

is therefore a parti-

The department wiLL BE cENTERED AT HAuPTMAN-

cularly fortunate align-

compensated by HWI,

ment for the Western
New York community,"

in addition to DeTitta

WooDWARD INSTITuTE [HWI], WITH UB OUTFITTING

he further commented.
DeTitta noted that

are

Robert H. Blessing,

ADDITIONAL LABORATORY SPACE IN ITS BIOMEDICAL

"this is an exciting time
for biomedical research
in Western

and Hauptman,

PhD, professor; Vivian
Cody, PhD, professor;

RESEARCH BurLDING o"N" THE SouTH CAMPus TO

ew York.

William L. Duax, PhD,
professor; and Walter

COMPLEMENT HWJ's FACILITIES .

Biological scientists at

A. Pangborn, PhD,
associate professor.

UB, Roswell, Kaleida,
D'Y ouville and Canisius have

Eleven additional HWI sci-

matical technique called "direct
methods," which has enabled

Foundation, HWI recently established a new robotics labora-

work-with structural scientists
at HWI. Today, we cement a

scientists around the world to

tory that will allow researchers

uncompensated faculty posi-

determine the three-dimensional

to grow a large number of pro-

tions in the department. Hold-

relationship that has been 40

structure of molecules rapidly
and automatically, using com-

tein crystals for X-ray structural

ing the rank of professor are

analysis in record time. UB has

Jeremy A. Bruenn, PhD, D.Y.

received $1.38 million through

Guo, PhD, and Charles M .

worked-and will continue to

years in the making.
"Out of this relationship, will

puter programs.

come medically relevant re-

The aim of structural biolo-

search of importance for its im-

ESG for research using

Weeks, PhD. Associate profes-

gists in the 21st century is to

nuclear magnetic resonance

sors are Jane F. Griffin, PhD,

pact on our health and on our

understand the operation of

(NMR) spectroscopy to deter-

Debashis Ghosh, PhD, David A.

local economy," he predicted.

biological systems at the subcellular, molecular and atomic

mine the structure of proteins,
adding to the department 's

Langs, PhD, and G. David
Smith, PhD. Assistant pro -

levels by studying the threedimensional structures of D A,
R A and proteins. Knowing the

armamentarium.

fessors are Chang I. Ban, PhD,

Faculty in the new department will perform advanced

L. Wayne Schultz, PhD, Yang-

structure of specific proteins will

research and train scientists in

liang Xu, PhD.

enable scientists to target new
drugs to treat chronic diseases.

the methods of modern structural biology. The department
will be centered at HWI, with

In addition, a number of fac ulty members from UB's graduate school division at Roswell

UB outfitting additional labo-

Park Cancer Institute and other

ruce Holm, PhD, senior associate dean in
the School of Medicine and Biomedical
Sciences, explained
that "structural biology is a scientific cornerstone in

the

entists are being appointed to

zhou Wang, PhD, and Hong-

the future of pharmaceutical

The collaboration combines
HWI's internationally known

development, and Buffalo is for-

expertise in X- ray crystallography

ratory space in its Biomedical

UB departments will be affiliated

tunate to have such world-class

with

Research Building on the

with the new department. ( D

UB's supercomputing

Spri11g

2001

Buffalo Physician

11

��Assassination in Buffalo
Time to put the medical controversy to rest?

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-•

.

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can still remember an afternoon stroll up High Street from the Buffalo General Hospital, where I was

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assigned as afourth·year clinical clerk in 1962. My destination was asmall bookstore at the corner
of Main (I can't recall its name, but someone will likely remind me). What I do remember, however, are
the nice people who worked there and my first purchase: awell· preserved copy of Selected Papers,

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Surgical and Scientific, by Roswell Park, MD, an esteemed professor of surgery at the University
of Buffalo and one of Western New York's most influential medical professionals at the close of the
19th century. As I sat down to read Park's book, which was published shortly after his death in 1914,
my interest was immediately drawn to the chapter titled "Reminiscences of McKinley Week."

Spring

2001

I HI IIID PbysitiiD

13

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ears later, I visited the Buffalo and Erie County Historical Society and took note of a display case
featuring artifacts from the events surrounding President William McKinley's assassination in
Buffalo at the 1901 Pan-American Exposition. Standing before the display, I viewed the assassin's
nickel-plated revolver, the unspent ammunition and a faded typescript. As I leaned closer, I saw
that the document was the original draft ofPark's "Reminiscences," made available to the historical
society in 1945 by his son, historian Julian Park. Several lines and paragraphs had been penciled
out, leading me to wonder what Park had written that he later decided his readers must not read.

As I progressed through my surgical training, I never forgot the

Pan-American Exposition's Temple of Music, where President

ing abdominal trauma, I came to understand what had likely

McKinley stood greeting well-wishers. The assassin, 28-year-old

happened to our 25th President, and why-after being shot twice

Leon Czolgosz (shole-gawz), was an angry, unemployed dissident

in the abdomen-his condition deteriorated so rapidly despite the
very best efforts of his surgeons. Eventually, I also became aware

from Cleveland, Ohio. Although Buffalo police detectives and the

of the fallen image of Buffalo and its surgical community due to

dent-as were several "special agents," forerunners to the Secret

the perception, by laymen and professionals alike, that the

Service-no one even managed to spot Czolgosz before he stepped

medical treatment the President received was substandard.
From a copy of Park's typescript, I learned of his concerns

73rd Coastal Artillery brigade had been assigned to guard the Presi-

up, thrust a recently purchased revolver at McKinley's breast and
fired twice.

ever intending to escape, and fully prepared to con-

about the operation that had been hastily performed on President

front the inevitable consequences of his act, Czolgosz calmly sub-

McKinley by a gynecologist, Matthew Mann, and about his convic-

mitted to the violent blows directed at him by a furious mob.

tion that abdominal drains would have made a difference in the

The President barely wavered and seemed to not know if he had

outcome of the case. Implicit in the remarks Park had crossed out
was the belief that the President's life could have been saved-and

been injured until he saw fresh blood on his shirt. Within moments,

the subsequent rebuke of Buffalo's med ical community avoided-

where a hastily assembled surgical team decided to operate rather

he was transferred to the exposition's modest emergency hospital,

if those who were making decisions about his care had waited for

than await the arrival of Buffalo's acknowledged expert, Roswell

Park to arrive instead of allowing the surgery by Mann to proceed.

Park, who at the time was operating in Niagara Falls.

Over the years, while researching my book Stolen Glory: The

Examination of McKinley's wound revealed that one bullet

McKinley Assassination, I have come to recognize that the prevailing

had bounced off his sternum, while the other penetrated the left

historical opinion of most 20th-century writers is that the surgery was

upper quadrant of his abdomen. Laparotomy was performed
under considerably disadvantageous conditions in that the patient

botched, an opinion that can still be elicited in Buffalo from many
who are aware of some of the details of the case. I believe, however,
that this is a conviction that is distorted by a century-old conception

14

the sudden, sharp report of gunshots pierced the grand hall of the

McKinley assassination story. With accumulated experience treat-

was significantly overweight, and lighting and instrumentation
were inadequate.

of McKinley's injury, as well as by comparisons to modern standards

evertheless, two gastric perforations were found and repaired.

of how his surgery and aftercare should have been conducted. In

Since no other injury was perceived (and the bullet remained undis-

contrast, I contend in my book that the available evidence, when

covered), the decision was made to conclude the surgery. While the

carefully considered in a historical context, supports a different

incision was being closed, Roswell Park appeared at the operating

conclusion; namely, that members of the surgical team available to

room door. He conferred briefly with Mann and then lent his hand

serve McKinley's needs acquitted themselves as well as anyone in the

to making arrangements for McKinley to recover in the Delaware

city or in the nation could have at that time, and that McKinley's

Avenue home of exposition President John G. Milburn.

wound in 1901 represented a mortal injury from the outset.
Stolen Glory begins with the anarchist movement and the climate

Meanwhile, the assassin had been transferred to Buffalo's downtown police headquarters before a lynch-minded crowd could assert

of terror that led to the assassination of six heads of state worldwide

its most fervent wish. Interrogation began at once and lasted

between 1894 and 1912; however, for the purpose of brevity, the
story can also begin on the afternoon of September 6, 1901, when

Czolgosz denied complicity with anyone, he cited as his inspiration

luf f a le Ph ys i till

Spri11g

2001

through the night, resulting in a signed confession. Although

--~

�America's notorious
anarchist orator,
Emma Goldman,
who was then hunted down across the
nation and eventually arrested in Chicago.
President McKinley awoke the morning after his
surgery and asked to see the newspapers. He was not
the least bit curious about his assassin; instead, he
wanted to know how the world had reacted to
the speech he delivered in the exposition's esplanade shortly after
arriving in Buffalo. Everyone assured him that his eloquent advocacy of reduced trade barriers in the Western Hemisphere had
been greeted with considerable enthusiasm. Each of his surgeons,
along with Park, expressed their delight with his quick mental and
physical rebound and through periodic bulletins kept reporters
informed that the President was destined for a prompt recovery.
Wall Street reacted enthusiastically to the news.
However, any physician today presented with all the evidence
available that morning would have recognized sure signs of trouble:
The President's pulse remained high-in the range at 120-and his

urinary output following surgery had only been 270 cc. Measurement of the blood pressure and red blood cell concentration were
not available in 190 l. Had they been, progressive hypotension and a
rising hematocrit would have been observed as the week passed.
Instead, all trained eyes were focused on bowel activity, the prevalent fear in that day being " intestinal toxemia." Accordingly, enemas
of every known variety were given incessantly.
On Thursday morning, the sixth postoperative day, Mr. Charles
McBurney of New York City, who had been summoned as a
consultant earlier in the week, visited the President again just prior
to leaving Buffalo. Meeting reporters afterward, his optimism was
apparent to all. When asked about the retained bullet, he jokingly
replied that it lay where it couldn't even shorten Methuselah's life

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by a single day.
o sooner had McBurney departed Buffalo's Terrace Street
Terminal than the President's condition began to deteriorate. His
pulse, then 130, was becoming weaker, his oliguria had persisted,
and efforts to administer saline by subcutaneous clysis had been
initiated too late.
Most physicians today will recognize that McKinley was in
shock, not because of hemorrhage, but because of the development of a pathologic third space with several liters of fluid having

Spring

2001

Bu ff al o Ph ysician

15

�accumulated deeply within an inflamed retroperitoneum. What

While Emma Goldman was still being hunted down as
Czolgosz's accomplice, the assassin himself was quietly arraigned
in a courtroom while reporters were diverted by the President's
funeral service in Buffalo, held a few hundred yards away. In a pace

McKinley had needed desperately, and did not receive, was intravenous fluid in significant quantity. Unfortunately, this was a physiologic requirement that would not be defined for many more years.
On Friday, a week after McKinley had been shot, the signs of progressive heart failure were apparent to all of his physicians. Every
known heart stimulant was used: strychnine, digitalis

of justice unimaginable today, a swift trial was followed by
electrocution of Czolgosz, all within six weeks of the shooting.
""·

During this same period of time, McKinley's surgeons
became the targets of stinging criticism from the press as well
as from their medical colleagues, whose denunciations were
paraphrased by journalists. In response, the sur-

and adrenal gland extract. Even brandy was
'"'~. '"~~,.~~'{·~~~\\
injected subcutaneously.
"''' •''"'~"tS ~ ""1.·
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More consultants hurried to Buffalo from
v~\'5 .... ..: ...
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turt:,lo ([outicr. -:::_
cities as far away as Philadelphia, Washington,
-:".-C\T~A!
D.C., and New York. Among them was Charles
~~: .'1lKI.\'LEY IS C\T~AI
McBurney, who, upon arriving home had been

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dumbfounded to learn of the President's condition
and promptly boarded another train bound
for Buffalo.
Their efforts were all to no avail. William McKinley,

"1\11 r h /II

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-- lli'~

25th President of the United States, died at 2:15A.M. on
Saturday, September 14, 1901.
The American public was stunned, for they had
been led to believe that their enormously popular
President would recover completely, an outcome many associated
with continued economic expansion and prosperity. Instead,
Americans were faced with a different kind of leader, Theodore
Roosevelt, the unlikely running mate in the 1900 election whom
McKinley advisors had called "a damned cowboy!"

geons sought counsel from an attorney, and a
statement was later issued assuring the public that
they had been of one mind throughout the time
they cared for the President, a distinct stretch of the
truth. Congress meanwhile debated whether or
not the surgeons should be paid for their services
from the McKinley estate. Eventually they did allow

funds to be appropriated from the national treasury
because Mann and his chosen assistants had been
serving McKinley in his capacity as President.
Soon after McKinley died, Roswell Park dictated his recollection of the events surrounding the President's
medical care. Once he completed this exercise, he placed the transcription in a desk drawer, where it remained for several years.
Shortly before he died in 1914, he edited his comments, and the
revised narrative was published true to his wishes. Not until 1945

Advanced Trauma Life Support (ATLSJ protocol. One of the technicians

What 11 · McKinley Were Shot Today

Secret Service personnel, while another would establish whether the

n this, the lOOth anniversary of President William McKinley's

other would be in charge of cardiovascular resuscitation of the patient,

or nurses would take a history from paramedics or, in this case, from the
President's airway and breathing are intact. At the same time still an-

death, I have been asked by Buffalo Physician to comment on

starting large-bore catheters in each of his anns and initially running

how the injured President would be treated today and how

approximately two liters of fluid if he showed signs of tachycardia or

surgical care has changed since 1901. I have consulted with

shock. At this time, we would also perfonn a thorough physical exam-

Dr. Fisher on this and am eagerly awaiting his new book.

ination, from head to toe, front to back.

It should be first emphasized that the care rendered to the
President would be no different than that given to any other

X-rays to detennine the location of the bullet and its possible course. In

patient in the Trauma Center of the Erie County Medical Center; that is,

the case of President McKinley-or in the case of this hypothetical

the same care is rendered to all patients without regard to their status. An

patient-the entrance wound in the abdomen was anterior, and the

in-house trauma-call team is present in the hospital 24 hours a day to

bullet lodged posteriorly. Approximately 20 to 30 minutes after arrival

respond to emergencies, and all trauma team members carry special

in the Emergency Room, the patient would be taken to the operating

trauma pagers. If we have advance notice, a

room for exploration of his abdomen. (Specialized tests such as CT scan

team of surgical residents, technicians and ER

and MRis are not utilized in penetrating trauma.) The surgeon would

personnel is available-gowned, gloved, and

make a generous midline incision and perform a thorough and complete

ready to go-in the Emergency Department.
When treating the patient, we use an approach that follows

16

After we ascertained that the patient was stable, we would take

l1ffalo Physiciaa

S prin g

20 01

exploration of the abdomen. The incision might also be extended into
the chest through the sternum to gain access to the heart and lungs as

�was the original draft made available for historical interpretation . A
comparison of the two documents reveals an edited version that is
soft in tone and reflective of the determined effort made by everyone involved in the tragedy to bring order to the chaotic events that
initially surrounded it. Perhaps it also shows a mellowing of
Park's estimation of events after the passing of a dozen years.
The unedited draft, however, clearly displays considerable angst
on the part of Park and perhaps a degree of resentment as well.

In it, he raises four issues: First, the haste in which the operation
was performed despite the fact that there were no signs of
hemorrhage and the President appea red stable; second, the
inexperience of the principal surgeon , Matthew Mann, who,
although a skilled gynecologist, had no prior experience with
gunshot wounds to the abdomen; third, the inadequacy of the
facilities used for the surgery (Park recorded that, in h is estimation, the President should have been transferred to the newly

c

.

"

,

•
needed. In an exploration for trauma, the surgeon would follow

resect the pancreas using a stapler. Ligation of the splenic artery and vein

these priorities:

would be done and the whole specimen removed in one piece. The surgeon

1. Control of hemorrhage;

would place suction drains, and the abdomen would be closed quickly.

2. Control of contamination;

Once the operation was completed-which a senior surgeon would

3. Identify and evaluate all of the injuries;

probably do in about two hours-the patient would be taken to the

4. Debride all devitalized tissue and remove all contamination and repair

ICU, where a trained team of critical care specialists would monitor his

and treat all of the injuries with appropriate surgery;
5. Close the patient.

care. This would include urine output, NG output, and other parameters
to optimize blood pressure, pulse and fluids. The team would also support
the cardiopulmonary and metabolic needs of the patient as needed.

In this case, we would debride and close the wounds of the anterior

In all likelihood, the President's hospital stay would be approximately

and posterior portion of the stomach. If bleeding was encountered, we

7 to 10 days without complications such as pneumonia or a pancreatic

would give the patient blood.

leak. In all, a total of 100 to 200 physicians, nurses and technicians

During surgery, the President would be monitored as if he were in an

would have been either directly or indirectly involved in his hospital

intensive care unit IICUJ. Using clamps, the surgeon would take down the

care. Clearly, the intensity ofthis care and the resources necessary to suc-

gastrocolic ligament and omentum between the stomach and colon and

cessfully manage such a patient justify the need for a trauma center.

explore the underside of the stomach and pancreas. (The bullet that
penetrated President McKinley traversed his pancreas to the left of the

Dr. Seibel is a clinical professor of surgery at the University at Buffalo School

superior mesenteric artery and vein, probably damaging the pancreatic

of Medicine and Biomedical Sciences and director of Surgery and Trauma

duct.) After the stomach and pancreas were explored, the surgeon would

Services at Erie County Medical Center in Buffalo, New York. He wishes to

mobilize the spleen and tail of the pancreas towards the midline and

thank Dr. john LaDuca for his assistance in editing this article.

S p ri n g

2 001

IDIII I O Physiciu

17

�expanded Buffalo General Hospital); and fourth, the omission of
inserting abdominal drains.
The autopsy revealed that both gastric suture lines were intact
and that there was no peritonitis nor any collection of pus, although
cultures taken at the postmortem examination grew a mixture of
organisms. A large gangrenous cavity behind the stomach was
consistent with significant inflammatory damage to the pancreas
and adjacent organs. Also, the heart showed severe fatty changes
consistent with failure.
Unfortunately, McKinley's case preceded by several decades
experiments performed by Alfred Blalock and Owen Wangensteen
in which they showed that surgically induced ischemia followed

by inflammation could result in clinical shock in the absence of
hemorrhage. Specifically, they determined that blood volume contracted as fluid was drawn from the plasma and interstitial spaces
in order to support a zone of severe inflammation. Without
intravenous replacement of that fluid loss, they concluded, death
would likely result from a failing heart.
By addressing Park's four issues from the perspective of surgery
as it was practiced in 1901-together with the hindsight inevitably
gained by a century-long interlude-! have drawn the following
conclusions about his concerns:
In 1901, McKinley appeared clinically stable to his physicians.
The standard response to any penetrating injury to the abdomen

What

attend the event has already been asked by the Secret Service to sub-

c

.

0

,

mit their social security numbers to permit security checks. The ad-

McKinley Needed Protection Today

vance team inquires about potential public demonstrations involving
local or national controversies. If required, a site for these protests will
be designated within sight of the President's motorcade. The Secret

n 1901, the Secret Service had not been charged with the responsi-

Service cannot abridge constitutional rights of assembly or protest.

bility of protecting the nation's President. After the McKinley

When the President arrives in Buffalo, usually by air, he is driven by

assassination, Congress corrected that omission. Today, the

the Secret Service to the event. His route is never revealed in advance to

Secret Service's capacity and impact far

the media as McKinley's itinerary was in 1901. At the Historical Society,

exceeds its modest presence a century

no person unknown to the Secret Service comes within range of the

ago. The following excerpt from Stolen

President, with one exception. A space for bystanders has been desig-

Glory: The McKinley Assassination, by Jack Fisher, MD '62, (see
article on page 121 considers how the Secret Service would prepare
today for a presidential visit to Buffalo, New York, and how it would

nated and cordoned off behind the television cameras approximately
75 feet to the side of the front entrance.
After the President has fulfilled his obligations and bidden farewell
to local political leaders attending the event, he departs through the

respond if a similar attack were to occur.
The President will be attending a series of events in Buffalo that in-

Historical Society's front entrance. Surrounded by his protective de-

clude an award ceremony at the Historical Society, the former New

tail, he stops, turns toward the television cameras, and waves. At that

York State Building for the 1901 Pan-American Exposition. The Secret

moment, the unthinkable occurs! A young man standing among the

Service was informed two weeks in advance of the planned visit. Special

bystanders draws a revolver from his pocket, aims, and fires twice at

agents in Washington coordinate with their counterparts in Buffalo,

the President before he is brought down. The Secret Service agents

where one of 116 field offices is located. The Protective Intelligence

close in around the President, prepared to take additional bullets if they

Section begins its database search of individuals in Western New York

come. They quickly pile into the car and depart.

who made prior threats to a President or other government official.

Police had already halted traffic on Elmwood Avenue, facilitating their

Meanwhile, an advance team visits Buffalo and determines the

entry onto the Scajaqueda Expressway, a planned emergency departure

President's actual motorcade route. The team contacts the Erie

route. Inside the vehicle, a still alert President identifies fresh blood on

County Highway Department to determine where construction projects

his shirt. Seeing this, a special agent alerts the driver to proceed im-

might impede movement. Dr. Roger Seibel, or his designate, at Erie

mediately to ECMC. Their limousine enters the passing lane and acceler-

County Medical Center (ECMCJ will be notified of the visit. [See "What

ates. On a closed-communication system, the Trauma Center is notified

If McKinley Were Shot Today," on page 16.]

of their approach. They exit at Grider Street and arrive at the trauma

Planning is coordinated with the Buffalo Police Department; its
responsibilities will include traffic and crowd control. At the Historical

receiving ramp six minutes after departing the scene of the attack.
At that point, Dr. Seibel's team takes over.

Society building, all doorways and spaces are checked, with the aid of

18

explosives-sniffing dogs. This will be repeated on the morning of the visit

The author is grateful to the Secret Service for their assistance providing

and at that time, the building will be secured. Everyone designated to

archive documentation from 1901, and for reviewing this descriptio11.

laffalo Phys i c i an

Spring

2001

•

�then-as it is today-was prompt surgical
exploration. Waiting would not have
helped the President.
of. In 1901, gynecologists performed

many more laparotomies than did general surgeons, albeit not for gunshot wounds. However, Mann had selected two surgeons to assist him who were experienced with injuries of the
kind that McKinley had experienced.

+

In 1901, elective surgery was often performed in private homes because

infection was prevalent in hospitals.

+

In 1901, the placement of a drain meant use of long rolls of stiffened

gauze. Plastic tubes attached to wall suction were not yet imagined.
Thus, I conclude that it is extremely unlikely that significant changes in the course of
treatment provided to McKinley by his surgeons would have made any difference in the
outcome of his case.
either is it likely that Roswell Park could have saved President McKinley, as the fate he
suffered resulted from errors of omission, not errors of commission. Those errors were unwitting on the part of Mann, Park and their associates, none of whom understood surgical
physiology as we know it today.

or did they benefit from the capability we have today of

monitoring our patients' myriad life functions or from having at our disposal the intravenous
fluids and pharmaceutical cornucopia for critical life support.
Given a careful and thorough review of historical facts surrounding the medical treatment
provided to President McKinley by Matthew Mann, Roswell Park, and their medical colleagues,
I believe that events surrounding his care should no longer represent a disparaging chapter in
Buffalo's history. Any reconsideration of the McKinley tragedy should be nothing less than a
celebration of one hundred years of medical and surgical progress culminating in a century of
achievements that Buffalo's surgical community has contributed to significantly.

jack Fisher, MD '62, is an emeritus professor of surgery at the University of California at San
Diego, where he is currently a master's candidate in United States history. His book, Stolen
Glory, The McKinley Assassination, will be available in july 2001 by subscription. For further
information, contact Alamar Books at P.O. Box 2876 La jolla, CA, 92037, or by e-mail, at
Alamarbooks@aol.com. Dr. Fisher can also be contacted by e-mail at jfishermd@aol.com.

�'

.

-

--

---

-

PATHWAYS

N EWS ABOUT ALUMNI, FACULTY AND STAFF AT THE UNIVERSITY AT

UB's

School

of

Medicine and Bio-

BUFFALO SCHOOL OF MEDICINE AND BIOMEDICAL SCIENCES

medical Sciences, in
the September 2000
issue of the New

Craig Smith,
Distinguished
Alumnus Visitor
Craig Smith, MD '72, chief
executive officer of Guilford
Pharmaceuticals, recently visited
University at Buffalo's School of
Medicine and Biomedical Sciences as a Distinguished Alumnus Visitor.
During his stay, Smith
met with students,
members of the Dean's

contains

ner held on April 26, 2001, at the

BCNU, or carmustine, a cancer

University Club in New York City.

England Journal of
Medicine, has been
selected by Harvard
Health Letter as

chemotherapy drug used in the

In announcing the award, Gregory

one of the top 10 health advances

treatment of glioblastoma multi-

L. Eastwood, MD, president of

of2000.

forme, a particularly virulent

AMS, told

that agency in over 20 years. This

cal Schools (AMS) of New York at

wafer, which is made of a biode-

its annual Deans and Trustees din-

gradable

polymer,

search and graduate deCRAIG SMITH

partments to discuss
work under way at

form of brain cancer. Currently,

Deans wish to recognize your long

winter 2001 issue of Buffalo Physi-

service to the organization, in-

trials for a diagnostic test it has

cluding your tenure as President,

outstanding leadership you have

cian, showed that early treatment
with one of the drugs used to control multiple sclerosis (MS)interferon beta-1a-reduced the
rate of development of clinically
definite MS for these high-risk
individuals by 44 percent versus

provided to the

treatment with placebo.

developed for Parkinson's disease.

during which [time) you spear-

-S .A.

headed a restructuring of AMS to

UNGER

strengthen its statewide scope. We
also wish to call attention to the

Naughton Receives
AMS Distinguished
Service Award
john Naughton, MD, dean of

Guilford Pharmaceuticals, which

UB's School of Medicine and

he helped establish in 1993 to dis-

Biomedical

cover and develop drugs to diag-

Sciences from

ew York State

Consortium on Graduate Medical

jacobs was the first American

Education and the many other

researcher, beginning in the 1970s,

ways in which you have served

to test a form of beta interferon, a

academic medicine in New York."
-S.A. UNGER

the body, in the treatment of MS.

naturally occurring substance in

nose, treat and prevent brain can-

1975 to 1996,

cer and other neurological dis-

was present-

eases. Guilford's leading product,

ed a Distin-

the GLIADEL wafer, gained Food

guished Ser-

.Jacob's Study
Touted by Harvard
Health Letter

and Drug Administration approval

vice Award

A study published by Lawrence

of beta interferon. His prior re-

in 1996, becoming the first brain

by the Associated Medi-

jacobs, MD, Irvin and Rosemary

search has shown that the drug,

Smith Professor of Neurology in

approved by the Federal Drug

cancer treatment to be cleared by

GREC.ORY

L.

EAsrwo&lt;..m, MD, PREsiDENT

10 (, -,~!{VIC f

ro

Since that time, he has lead several

joHN NAUGHTON

m

AMS,

.ow NALGHTO

MS studies using interferon beta1a, a genetically engineered form

rHAT "n!E DEA. 'SWISH

ro

RECOG IZF YOt:R

lHE ORC,A I?ATIO , INCLL DING YOCR Tf.Nl RE AS PRESIDE 'T, DURL 'G WHICH [TIME] YOU SPEAR-

HEADED A RES.RLC TURI c, Or AMS ro STRENG!HEN ITS STAlFWIDE SCOPE."

20

The study, also reported in the

the company is involved in clinical

Advisory Council, and
faculty in several re-

aughton that "the

LAWRENCE jAcoss

l u fla la Pb ysicin

Spring

200/

�Administration in 1996, slows the
accumulation of physical disability and decreases the frequency of
clinical flare-ups in patients with

.Jehle Honored by
ACEP for Teach ng
Dietrich Jehle, MD, FACEP,
clinical director of Emergency
Services at the Erie County

relapsing forms of MS.
- Lots BAKER

Medical Center, has received the
ational Emergency Medicine
Faculty Teaching Award 2000

Holm Named a Top
SUNY Researcher
Bruce A. Holm, PhD, professor of
pediatrics, pharmacology and
toxicology, and gynecology/
obstetrics at UB's School of
Medicine and Biomedical Sciences, was honored as one of the
SU Y system's top research scientists at a dinner held in Albany,
New York, on January 22, 2001.
Holm, who is also senior associate
dean at the School of Medicine
and Biomedical Sciences, has
conducted internationally recognized
research on lung
surfactant and oxygen toxicity affecting alveolar cells.
In his address to
the evening's 21
BR UC E

A.

HOLM

honorees,

SU Y

Chancellor Robert
L. King said, "Each of you has

distinguished yourself and our
university by the body of your
work. Learning of the specifics of
[this] work has validated all of my

from the American College of
Emergency Physicians (ACEP ).
Jehle, who is associate professor
and vice chair
of the Emergency Medicine Program
at UB 's School
and BiomediDtETRt C H J E HL E

plays host to tremendous research
initiatives and has, and will, continue to make great contributions
to our state, our economy and
our society."
-Lots BAKER

tional Institute of Allergy and

ant at RPCI

Infectious Diseases, National

stnce

Institutes of Health.
- S.A. U N GER

1999,

has also been
appointed to

BRAHM H. SE GA L

the faculty position of assistant
sions of Infectious Diseases and

Sethi and Berenson
Funded to Study
Emphysema

Allergy, Immunology, and Rheu-

Sanjay Sethi, MD, and Charles S.

professor of medicine in the Divi-

matology at UB's School of Med-

Berenson, MD, in the Department

icine and Biomedical Sciences.

of Medicine at the University at

Segal earned his medical de-

Buffalo, have been awarded a

gree from Albert Einstein College

four-year, $750,000 grant from

ew York.

the National Heart, Lung and

He completed residency training

Blood Institute of the National

ew

England Medical Center, Boston,

CON TI NU ED ON

P ACE 22

cipient of numerous awards, including the
Outstanding Mentor/Teaching

STUDENTS' ANNOUNCEMENT

Award and the Chairman's Teaching Award from UB's Department
of Emergency Medicine.
Jehle is recognized for devel-

tudents for Health and Human Rights (SHHR), a local
offshoot of Physicians for Social Responsibility (PSR), has

oping the first study of bedside

several members who are interested in recycling surplus

ultrasonography in abdominal

and unused medical supplies from hospitals for use in

trauma by emergency physicians

developing countries. This type of program was first

orth America. He is also co-

developed at the Yale-New Haven Hospital several years ago

editor of a trauma ultrasound text

and has been successfully implemented in hospitals across the

that will be used as an instruc-

United States.

in

tional guide for future ACEP

The program works as follows: Supplies for patients are often

Trauma Ultrasound courses fol-

unused, but according to law cannot be reallocated for use with

lowing its publication in 200 l.
- S.A. UNGER

other patients in the United States. Our organization is interested
in systematically recycling these supplies and sending them abroad
in keeping with the Yale-New Haven Hospital model, and we are

we, as a great research institution,
proven that the State University

in Infectious Diseases at the Na-

eases consult-

in internal medicine at the

cal Sciences,

beliefs and my vision for where
can go. Your achievements have

infectious dis-

of Medicine, Bronx,

of Medicine

is the past re-

Massachusetts, and a fellowship

has been an

interested in finding a local hospital that is willing to participate

Segal Named
Assistant Professor
of ed"c ne

in this program. We have several potential recipients in Haiti and
other countries in desperate need of supplies.

Brahm H. Segal, MD, has been ap-

If you know of a hospital or administrator who would be willing

pointed director of the Division of

to assist us in this endeavor, please e-mail Christina Chang at

Infectious Diseases, Department

cmcll@buffalo.edu; Betsy Schneider at eas26@buffalo.edu;

of Medicine, at Roswell Park

or Sarah Gaughan at sgaughan@buffalo.edu.

Cancer Institute (RPCI ). Segal, who

S prin g

200/

Buffa l o Pb ysi c i an

21

�PATHWAYS

Tm

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COST

EFFECriv~, PREY~

CO

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BL HAlo,

, F\\ YoRK, cALLS HIMSELF A. " 1A AG£D CARF IDEOLOGuE" \\ HO sEEs "HIGH-QC'ALITY,
T

fiH-ORIFNTt:D

M~DIUNE

.•. PRACTICED BY A GROUP Of PROVIDERS \\HOARE WILLI, "G TO

,I LOl SL'I AS~FSS A D IMPROVE THEIR l.)L \lLY OF CARE" AS THE BFSr \\AY ro DELIVER HEALTH CARE .

however, the

CONTINUED FROM PAGE 21

Institutes of Health to study the
precise role that respiratory bacteria (Haemophilus injluenzae) play
in regulating immunologic mechanisms of inflammation that lead
to chronic obstructive pulmonary
disease or emphysema.
It has long been known that
inflammation is present in the air-

critical

care

medicine-and

effective therapies in the future.

role that bac-

Berenson-an associate professor

Both Sethi and Berenson are

teria play in

of medicine who is board certified

affiliated with Veteran Affairs

decreasing

in infectious diseases-will com-

Western New York Health-

function has

bine

care System's Bailey Avenue

their

clinical

and

not been ex-

research interests in an effort to

facility, where the research will

plored. In this

provide a better understanding

be conducted.
-S.A. UNGER

study, Sethian assistant

of the basic causes of emphySANJAY SETHI

sema. Such an understanding

professor of medicine who is

may in turn provide a basis for

board certified in pulmonary and

designing

ways of people with emphysema;

novel

and

more

Robert Dickman, MD '68, Named Chair at Tuhs University
n April 5, 2001, Robert L. Dickman, MD '68, was installed as the

That philosophy was the foundation of his work as director of

inaugural holder of the Jaharis Family Chair in Family Medicine

ambulatory services at the Buffalo General Hospital, beginning in

atTufts University School of Medicine in Boston, Massachusetts.

1972, and as a faculty member at University at Buffalo's School of

This is the first endowed chair of Family Medicine in

Medicine and Biomedical Sciences, where he earned his

New England, and one of approximately 14 others

medical degree in 1968.
It guided him later him as a faculty member of the

in the country.
Dickman formerly served as chief of Tufts' Division

Family Medicine Center at Case Western University;

of Family Medicine, which he came to the university

helped his creation, in 1982, of a new Department of

to create in 1998. This effort involved strengthening

Family Medicine at Cleveland's Mt. Sinai Medical

existing family medicine programs and developing

Center; and informed his work as a consultant for

new ones, including a required third-year clinical

Meridia Health Care Systems, as well as in his estab·

clerkship. Experienced in shaping new organizations,
ROBERT DICKMAN

Dickman in 1971 was a founding physician of the
Matthew Thornton Health Plan, one of the Northeast's
first health maintenance organizations.
Throughout his career, Dickman has integrated the principles

In 1995, Dickman took the same philosophy to
Israel, where he directed managed care programs at Maccabi Health
Services, Israel's second largest health fund.

of family medicine and managed care in academics, practice and

In addition to his interest in managed care, Dickman has pursued

management. The native of Buffalo, New York, calls himself a

clinical and publishing interests in geriatrics, most recently con-

"managed care ideologue" who sees "high-quality, cost-effective,

tributing to a major family medicine text; and medical ethics,

preventive-oriented medicine ••• practiced by a group of providers

especially end-of-life care issues.

who are willing to continuously assess and improve their quality of
care" as the best way to deliver health care.

22

lishment of a family medicine group practice in
Cleveland.

laffalo Phys ic ian

Spring

2001

Dickman will continue to administer the Tufts' medical school
family medicine programs.

�Jerome Kassirer Honored by American Jewish Congress
Distinguished Community Leadership Award
erome Kassirer, MD '57, received the Distinguished

referred to as the 'conscience of American medicine.' Kassirer's

Community Leadership Award from the American

reputation as the 'conscience of American medicine' was furthered

Jewish Congress on February 7, 2001, at a ceremony

in July 2000, when he stepped down aseditorofthe N£/Minthewake

held at the Westin Copley Place Hotel in Boston,

of a decision made by the journal's publisher, the Massachusetts

Massachusetts. The American Jewish Congress, which

Medical Society, to begin adding the tagline "publishers of the New

in its own literature refers to itself as the "Attorney

England Journal of Medicine" to its other publications.

General for the Jewish People," is an 80-year-old

After graduating magna cum

organization that works around the world to pro·

laude from UB's School of Medicine

mote religious freedom and diversity, defend the

in 1957, Kassirer trained in internal

civil rights of minorities, and guarantee the consti·

medicine at Buffalo General Hos·

tutional rights of all Americans.

pital and in nephrology at the New

In presenting Kassirer with the award, the Con·

England Medical Center in Boston.

gress notes that "as editor-in-chief emeritus of the

He joined the faculty at Tufts Uni·

New England Journal of Medicine {N£/MJ [he] has

versity School of Medicine in 1961,

made outstanding contributions in the areas of

was named professor of medicine in

medical care, education, research and health policy.

1974 and was the Sara Murray

He has had a distinguished career as a caring physi·

Jordan Professor of Medicine from

cian, outstanding educator, researcher, innovator in

1987 to 1991. From 1971 to 1991
he was associate physician-in-chief

clinical reasoning, and leader in promoting profes·
jEROME KAS S JRER

sional values. In numerous editorial op-ed pieces and

of the New England Medical Center

commentaries over the past two decades, he has

and vice chair of the Depart-

criticized our inadequate medical care delivery system, govern·

ment of Medicine at Tufts. In 1991, he became the 38th editor-in·

mental interference in medical decision making and the resis·

chief of the New England Journal of Medicine.

tance of the gun lobby to support reasonable safety measures.

Also in 1991, Kassirer was named Distinguished Alumnus of

He has tirelessly promoted integrity in patient care and re·

University at Buffalo's School of Medicine and Biomedical Sciences

search, endorsed a stronger role for patients in medical deci·

and received the Distinguished Faculty Award from Tufts University

sions and been a careful observer of the role business interests

School of Medicine. He now teaches at Tufts, as well as at Yale

have played in our American health-care system. During his

University School of Medicine.

tenure at the New England Journal of Medicine, he was often

- S . A. U N c E R

Spring

200 1

l uffafo Physician

23

�M

B v
S
U

N

A
G

E

R

E

D

C

A

L

S

C

H

0

0

L

E

W

S

AWealth of Knowled eand (xperience
N e w M e d i c a I E m e r i t u s Fa c u I t y G r o u p Fo r m e d

has found its
counterpart in lifelong teaching and mentoring through
a new group formed at University at Buffalo's School of
Medicine and Biomedical Sciences. The group-called
the Medical Emeritus Faculty Group (MEFG)-was
begun last year in an effort to provide retired faculty with
an opportunity to continue viable, interactive relationships with the medical school once their formal academic
careers have come to a close.
The MEFG got its start in January 2000, when Glen
Gresham, MD, emeritus professor and chair of the
Department of Rehabilitation Medicine at UB, met
with Dean John R. Wright, MD, to discuss the idea of
creating a more uniform way in which retired faculty
could continue to stay connected with the school should
they choose to do so.

"In the past, when medical faculty members retired
but wanted to stay involved with the school, they
worked out informal arrangements with their former
departments, but there wasn't a uniform approach to
this transition," Gresham explains. "Also, there was no
place for us to get together and to feel a part of a peer
group. Many of us are in Buffalo for at least part of the
year, but our interactions with the school were
random-anything from being on the mailing list for
Buffalo Physician to being invited to a lecture or some
other event. It was kind of'luck of the draw."'
ln talking with Dean Wright, Gresham explained that
he and a core group of his colleagues felt they were not
alone in perceiving that an attempt to establish an emeritus faculty group would be well received by a significant
number of their peers.
"Dean Wright was very supportive of this idea and
suggested that we go ahead and pursue it," says
Gresham. "He gave me the names of some
people he thought would be interested and
to this list we added other names to
form an ad hoc steering committee,
which began meeting monthly in the
summer of 2000."
The steering committee
has been meeting on an ongoing
basis since then and its members
have embarked on an outreach
effort aimed at inviting as many
of their peers as they can locate to
join the MEFG. With the assistance of Mary Glenn, from the offices of Alumni and Development,
whom the Dean assigned to serve as a
liaison with the group, committee members have contacted retired faculty by
phone and letters, as well as by word of mouth.
Currently, they are preparing to send out a questionnaire to all medical emeritus faculty in the school's
database, which has approximately 200 names in it.

.."..

,..
•
0:

24

lulfale Physiciaa

Spring

2001

�((Many of the current emeritus faculty have been leaders within the school and have
a rich sense of history due to their long tenure here. They will be respected and
effective ambassadors for the school." -Dean

Gresham says he was pleasantly surprised when he
reviewed the database, name by name, and identified
193 emeritus faculty who still list a principal address in
Western ew York. "I had no idea there were so many;
I thought maybe there would be 50, " he
says.
"But what I found is that there are a
In the long run,
lot of us. "
Gresham foresees a
The response to invitations to join the
number of other group has been extraordinary, according
to Gresham, who explains that memberinterest groups
ship is open to anyone who meets the
forming to establish a criterion of being an emeritus professor
or faculty member from UB's School of
"bank of expertise"
Medicine and Biomedical Sciences.
that's available to "This is a first-class group, and we'd be
anyone who wishes to delighted to have anyone join who ' s
interested," he says.
draw upon it.
Since its formation, the MEFG has
accomplished its initial objective, which,
according to Gresham, "was to bring us together and see
how well we got along and to see what we might be
interested in doing.
"We all worked together a long time and have much
in common, and what we have found is that we do like
seeing each other," he continues. "We really are a cohort; we are a group. And this has been very gratifying
to confirm. "
Another objective the group's members have agreed
upon, is that they would like to remain an informal
entity. "One of our members was very wise and said we
should go slowly and not be in a hurry to become overly
organized and have officers and bylaws and such
things," Gresham says. "He suggested that we just 'let it
grow,' so that's what we're doing."
Having reached a consensus that there is indeed a
place for such a group, and that its organizational style
should remain informal, the MEFG has set to work
planning specific events and tasks. Last fall, they began
hosting bimonthly roundtable lectures featuring
distinguished speakers from the medical school who

John R. Wright

address topics put forth by the group. In November
2000, for example, Michael Bernardino, MD, MBA,
vice president for Health Affairs at UB, spoke on
"What Is the Relationship between the School and
the Hospitals in Buffalo? " and in January 2001,
Dean Wright spoke on "Where Is the School Now and
Where Is It Headed?" The roundtable format has proved
conducive to discussions between the speaker and
members of the group, according to Gresham.
In addition to the roundtable luncheons, the MEFG
has formed a sub-set of interest groups that draw upon
the special expertise of its members. "There's a lot of
interest in medical education among our members,
particularly with regard to mentoring and tutoring, "
says Gresham. "We are a group that has enormous
experience in these areas and many still feel they have
much to contribute."
To date, two such interest groups have been formed:
One, headed by jacob Steinhart, MD, an emeritus
professor of pediatrics, is aimed at working with
physicians-in-training to hone their interactions
with patients and to cultivate "clinical wisdom";
and a second group, headed by john Robinson, MD,
an emeritus professor of psychiatry, is aimed at providing support to medical students interested in
learning more about post-traumatic stress disorder.
In the long run, Gresham foresees a number of
other interest groups forming to establish a "bank of
expertise" that's available to anyone who wishes to
draw upon it. "Depending on who comes forward, I
anticipate a variety of interest groups that capitalize on
the strengths of our members," he says.
Another specific task the MEFG has set its sights on
is the completion of the emeritus faculty questionnaire, which they hope will help them to better define
the group's goals and potential contributions for the
future. They also hope to obtain office space for headquarters that would provide them with a place for small
CONT I NUE D

ON

PA GE

26

S prin g

2 001

11111 11 Pbys i c i11

25

�----

M

E

D

----- -

C

A

L

SCHOOL

E

W

S

"In the past, when medical faculty members retired but wanted to stay involved with the
school, they worked out informal arrangements with their former departments, but there
wasn't a uniform approach to this transition," Gresham explains.
KNOWLEDGE,

CONTINUED

FROM

PAGE 25

meetings, a phone, fax and computer. "We envision the
office being staffed by volunteers who can give of their
time to help us accomplish another of our goals,
which is to keep a master schedule for all the fascinating medical and scientific lectures at the school and

Charles Paganelli, PhD, an emeritus professor of
physiology and biophysics who is also a member of the
MEFG steering committee, says "It's been a pleasure to
see people you've known for years and to work with
them in this capacity. This is a group of senior faculty,
now retired, whose members have lots of experience
around the school and there's no reason why their

throughout Buffalo," explains Gresham. "Right now,

accumulated knowledge can't be used by the school to

these events are spread all over the place and nobody
keeps a master calendar that could be made available to
our members and whoever else would like to avail
themselves of this information."

some good purpose."
Gresham and his fellow members of the MEFG's
steering committee know that to effectively accomplish
the goals they have outlined, they must integrate the
group's presence into the fabric ofUB's School ofMedi-

therefore, view themselves
as a resource that not only can be tapped into by
others but that can reach out to the school and community. "We've had wonderful careers and we're
proud to be emeritus faculty at UB," says Gresham.
"Many of us are very busy with volunteer work and
some of us continue to practice. So, it's not that
people aren't doing things; it's just that we haven't
been doing anything as a group with the school. And
the response we're getting from the school is very
affirming of our goal to interact in this way."
"The organization of an active, informed and dedicated emeritus faculty group is good news indeed for
the School ofMedicine and Biomedical Sciences and for
the university community," says Dean Wright. "Many
of the current emeritus faculty have been leaders within
the school and have a rich sense of history due to their
long tenure here. They will be respected and effective
ambassadors for the school."
Harold Brody, PhD, MD, emeritus professor of
anatomy and cell biology, and member of the MEFG's
steering committee, concurs with Wright and Gresham.
"A gap has existed because there hasn't been a group like
[the MEFG] in the past. Potentially, it could be a very
important group because it's made up of people who
care very much about the school and understand how it
works," he says.

26

lalfal1 Physiciaa

Spring

2001

cine and Biomedical Sciences so that when faculty members retire, they see the potential for involvement with
the MEFG as just another step in a continuum of interaction with the school. Toward this end, therefore, the
MEFG would like to initiate a new stage in the process
whereby a faculty member retires from the school.
"We now have a faculty meeting where people who
are retiring receive a 'diploma' that states he or she has
been promoted to the rank of professor emeritus with
all its rights and privileges," says Gresham. "In addition,
we'd like someone from the MEFG to immediately
approach those who have retired to say, 'welcome to the
Medical Emeritus Faculty Group.'
"In other words, we'd like to make it a seamless and
positive transition for those faculty who are interested
in continuing their involvement with the school."
For more information on the Medical Faculty
Emeritus Group, call Mary Glenn at (716) 829-2773;
or e-mail her at glenn@acsu.buffalo.edu.

�..James E. Allen, assistant
professor of surgery

Blake Reeves, professor of
physiology

Sprirrg

2001

l 11fale Hysicin

27

�....
G.&gt;

.....

=
.......

-

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-=

...

2.

1111111 Pkysitill

Spring

2001

��Hormones,

I n s u I

n

a n d

B r e a s t

'&gt; she has been looking at how

the blood levels of estrogens and androgens are associated
with the risk of developing breast cancer. More recentlywith the support of a two-year, $238,000 grant from the
United States Army Medical Research and Materiel Command-she has turned her attention to conducting the first
major study of the relationship between breast-cancer risk
and levels of insulin in the blood.

The Influence of Diet and Exercise
When breast-cancer researchers set out to explore questions such
as those Muti is pondering, they begin with the recognition that
breast-cancer incidence rates are about 25 percent higher in
Western countries than in Africa or Asia. "Although both
genetic and environmental
factors may contribute to explaining this large geographic
variation in incidence rates,
studies on migrants who moved from countries characterized by low incidence, such as
Japan, to countries at higher
risk, such as the United States,
have shown a significant increase in breast-cancer incidence in individuals that migrate in comparison with their
peers who remain in the countries of origin," Muti explains.
This evidence has led researchers to surmise that
environmental factors, such
as diet and lifestyle, play a
dominant role in breastcancer incidence, according
to Muti. "In countries with
high breast-cancer incidence
rates, these environmental
factors are characterized by an
energy-dense diet rich in total and saturated fat and refined
carbohydrates, and by low physical activity," she says.
In terms of what role genetics plays as a risk factor in the
incidence of the disease, Muti reports that "there are connections,
but, in absolute terms, genetic predisposition as it has been
studied up to now accounts for only 5 percent ofbreast cancer cases.
"However, it is possible that the way in which we metabolize
components of the environment-metabolize diet or pollutants-may give us a different risk in comparison with people who
metabolize in a different way," she adds.

3 0

I u fl a I a Physician

Spring

200 1

Cancer

Given that genes appear to play a lesser role in the development
of the majority of breast-cancer cases, Muti emphasizes that "at
this historical moment in research on this cancer, it is very important that we identify the environmental factors that are placing
women in our country at such high risk in comparison to women
in low-risk populations. Clearly, there are environmental factors,
but we really don't understand how they work."
One potential explanation of the role environmental factors
play in the etiology of breast cancer is that diets rich in total and
saturated fat and refined carbohydrates often lead to the development of insulin resistance and hyperinsulimia. Like hormones,
insulin is an endogenous substance; in other words, it originates
within the body, as opposed to exogenous factors, which arise
externally. These endogenous substances, Muti says, are
"big mediators between the environment and ourselves."
Muti's goal in her current study, therefore, is to
test the hypothesis of the linkage between serum insulin
and breast cancer. "We know that insulin itself is an
important mutagenic factor because it is able to induce
proliferation and growth of a cell," she explains. "The
mechanistic model we are working with now leads us to
hypothesize that because insulin can also increase production of androgens from the ovaries, and because androgens are the precursors of estrogen, insulin is then
able to produce both androgens and estrogens, which are
important factors for breast-cancer etiology."

F"nding Markers of Metabolic Risk
To conduct her study on the role of insulin in breast cancer,
Muti is building on a series of related studies she has
completed over the past decade. The studies are based on
data she gathered on almost 11,000 healthy women in Italy
between 1987 and 1992 for an initial prospective study on
breast cancer, called the HORmones and Diet
in the ETiology of Breast Cancer (ORDET) study.
Five and a half years after the women were recruited to
this original study, 144 were found to have developed
breast cancer. In the early 1990s, Muti and her colleagues
went back and looked at samples of blood from the
women who developed cancer and compared them with
samples from women who didn't develop the disease. It was this
important study, later replicated all over the world, that first
provided scientists with data indicating a definitive link between
the presence of high levels of estrogens and androgens in a woman's blood and the subsequent development of breast cancer.
In 1998, again relying on analysis of data collected on women
who took part in the ORDET study, Muti and her colleagues
conducted a study in which they sought to discover whether there
was a way they could determine a woman's hormonal (androgen)
and insulin levels other than by analyzing her blood-in essence, to

�lstrogen Metabolism linked to Breast Cancer Risk
and collaborators have

Researchers analyzed the

found that premenopausal women show a 40 percent lower

urine samples from both breast

risk of developing breast cancer if their predominant path-

cancer cases and controls from

way of estrogen metabolism produces by-products with little

the ORDET study to determine the

biologic activity, rather than by-products that are highly

predominant estrogen-metabolism

reactive. The research is based on data from 10,786 women

pathway. Results showed that the

who took part in a prospective study of breast cancer in Italy

premenopausal women who devel-

called the Hormones and Diet in the Etiology of Breast Cancer

oped breast cancer had a higher

(ORDETI study (see also article, opposite).
Once estrogen has performed its essential hormonal duties, it must be eliminated from the body by undergoing a
process called hydroxylation.
"Estrogen hydroxylation takes place at two primary sites on the
estrogen molecule, designated as the C-2 position and the C-16

percentage of the highly active byproducts of estrogen metabolism
(produced by the C-16 pathway),
than by-products from the C-2
pathway. Women with predominately C-2 pathway by-products-those with low activity-were 40

position," Muti says. "Earlier research has shown that hydroxyla-

percent less likely to have developed breast cancer during those

tion at the C-2 position produces metabolites with little or no

five years.

estrogenic activity and thus might be associated with decreased

"The way to change from one pathway to the other is through

breast-cancer risk. Conversely, hydroxylation at the C-16 position

changes in lifestyle. Physical activity and eating a diet low in fat

produces metabolites with high estrogenic activity, and might be

and high in cruciferous vegetables can shift estrogen metabolism

associated with increased breast-cancer risk. We set out to deter-

from high-risk to low-risk," says Muti.

mine if there was an association between later development of

For more information on this study, refer to the paper published

invasive breast cancer and the ratio of C-2 to C-16 by-products in

on it in the November 2000 issue of Epidemiology.

women before cancer developed."

- LOIS BAKER

discover whether biological markers exist for these substances
other than in the blood . To accomplish this, they assessed the
women's sebum production (the output of the skin's oil-andwax-producing sebaceous glands), their body-fat distribution and
amount of body hair. (The relation of excess androgen in the
blood with sebum production and symptoms of excess body hair,
or "hirsutism," has been recognized by researchers for many
years, Muti points out. In more recent years, clinical studies on
women with established non-insulin-dependent diabetes mellitus
and consequent elevated insulin concentration have shown that
they have higher abdominal fat.)

W

hat M uti found in her study was that hair and sebum production were predictors of breast cancer in older, postmenopausal women. Furthermore, the body-fat distribution that
fit a more male (pear-shaped) pattern, as opposed to the
female (apple-shaped) pattern, was a predictorofbreastcanceronly
in premenopausal women, in particular in women who were thinner. "One of the things this told us is that the hypothetical model
we have for describing the mechanism of how insulin is able to
induce increased production of androgens and estrogens as

&lt;!;)

precursors to breast cancer is not so simple; it's more complex
than we had thought. There are factors that make insulin a relevant
risk factor in younger women and there are factors that make
androgen and estrogen important risk factors in older women,"
says Muti. "In my present study on insulin, therefore, what I am
looking at is the potential determinant of why insulin is so important in young women, and why androgen and estrogen, and not
insulin, is so important in postmenopausal women."
To date, the results from Muti's current insulin study are
"telling us that insulin and IGF-1 [insulin-like growth factor- I),
when measured in the blood, are more important in premenopausal than in postmenopausal women."
These findings are leading Muti and her colleagues to hypothesize "that the insulin-resistance theory is stronger, is more valid,
for younger women," she reports. "In particular, what we're
finding is that glucose in the blood-glycemia-is a risk factor
for breast cancer in these women," she notes.
Based on these findings, she says, "we are very close at this
point in our research to finding markers of metabolic risk that
will tell us a little bit more about the potential markers of
these environmental factors for breast cancer."

Spring

200/

l a fla l a Pbys i c i u

31

�E

RESEARCH

W

S

Cocaine Use and
Heart Attacks
One- uarter of nonfa a heart
attacks among persons under
the age of 45 in the United
I

.
..•
&lt;

States can be attributed to regular cocaine use, scientists at
the University at Buffalo's
Toshiba Stroke Research Center
have reported in a study published in the January 2001 issue
of Circulation.
Lead author Ad nan I. Qureshi,

to Qureshi. "What we do know is
that cocaine use increases the
levels of the neurotransmitters
norepinephrine and dopamine at
nerve terminals, which in turn
increases heart rate, ventricular
contraction and the heart's
demand for oxygen.
"Cocaine may also constrict
blood vessels and increase platelet aggregation. In addition, it has

MD, UB assistant professor of

been shown to accelerate arter-

neurosurgery, and colleagues
found an association between
frequent cocaine use and heart
attacks in this age group, but not
between cocaine use and strokes.
"These findings
"Cocaine may
ndicate that changalso constrict blood
ng behavior sur-

iosclerosis in young patients.
Since regular, but not infrequent,
use of cocaine was associated
with an increased risk in our
study, our results seem to support

vessels and
increase platelet
aggregation. In
addition, it has been
shown to accelerate
arteriosclerosis in
young patients.
Since regular, but
not infrequent, use
of cocaine was
associated with an
increased risk in our
study, our results
seem to support this

rounding cocaine
use-due to public
awareness and education-may reduce
the incidence of cardiovascular disease
n younger persons,"
Qureshi says.
Previous researchers had reported
cases of heart attack and stroke in

persons who had
sed cocaine within
latter mechanism." the previous hour.
Given the increase
in cocaine use among young
adults in the United States, the
UB researchers undertook an
extensive investigation of the
possible relationship.

this latter mechanism," he says.
In their analysis the researchers used data from the most
recent National Health and
Nutrition Examination Survey
(NHANES 1111, which was conducted between 1988 and 1994
by the Centers for Disease Control
to estimate the prevalence of
chronic disease in the United
States population and identify
factors that put people at risk of
developing chronic health problems. It involved 40,000 persons
two months of age or older. For
the first time since these national
surveys began, participants ages
18 to 59 were asked about life·
time cocaine use.
For their analysis of the association with heart attack and

luffalo

Physician

Spring

stroke risk, the UB researchers
limited their study population to
the 18 to 45 age group, which
captured all but 25 cocaine users
and resulted in a study base
of 10,085.
The study group was divided
into three user groups: never, in·
frequent, and frequent. This included anyone reporting using the
drug from 10 to more than 100
times. The survey also contained
data on prevalence of nonfatal
stroke or heart attack.
Analysis showed that about one
in 20 subjects, 67 percent of
whom were males, reported
using cocaine regularly.
To estimate the impact of the
drug on nonfatal heart attack or
stroke, the researchers calculated the percent of populationattributable risk-the portion of
disease that would be eliminated

if the exposure lin this case, use
of cocaine) were removed.
In general, regular users of
cocaine were at nearly seven
times the risk of having a nonfatal
heart attack than non-users,
results showed. The populationattributable risk was 25 percent,
indicating that in this age group,
one in four nonfatal heart
attacks would not have occurred
if there had been no cocaine use
in the group.
There was no relationship between cocaine use and nonfatal stroke.
Additional researchers on the
study included M. Fareed K. Suri,
MD; Lee R. Guterman, PhD, MD;
and L. Nelson Hopkins, MD, chair
of the UB Department of Neurosurgery and director of the
Toshiba Stroke Research Center.
lOISBAK

R

searc

Researchers aren't sure how
cocaine might increase the
chances of having a nonfatal
heart attack or stroke, according

32

Adnan 1. Qureshi, MD

2001

�" THESF RESULTS SUGGEST THAT NATURALE

DOCA .• ABL OID-SIG"'JALI

G REGl.JlArF&lt;; SPER\1 FU CfiONS IN

HUMANS, Fl. 'DI. GS WITH :\1EDI&lt; AL IMPLICATIONS FOR HUMAN REPRODUCTIO.' AND DRUG ABUSE," SCHUEL SA Y::i .

Marijuana Abuse
and Fertility
For about the past 40 years, re-

concentrations were inhibitory,

stance called anandamide was

which suggests that localized

"In addition, the increased

differences in anandamide levels

load of cannabinoids in people

may regulate sperm swimming

who abuse marijuana could flood

found to be that chemical.

searchers have hypothesized that

Regulatory mechanisms that

marijuana smoke may affect
sperm fertility. A recent study

prepare sperm to fertilize eggs in
human reproductive tracts remain poorly understood. Human

THC inhibit structural altera-

adversely impact fertil-

scientists provides compelling

sperm are bathed in male repro-

tions, which are required for

ity," he says. "This may

"Defects in

evidence in support of this

ductive tract secretions when they

physiological acrosome reactions,

explain why men who

endocannabinoidsignaling may
be responsible
for certain

headed by University at Buffalo

In VIVO.

Secondly, both AM-356 and

natural endocannabinoid-signal
systems in reproductive organs and

theory by discovering that a

are ejaculated into the female's

over the acrosomal cap during

smoke the drug have

cellular-signaling system that
responds to THC (the active sub-

vagina, and are not immediately
capable of fertilizing eggs. How-

capacitation.
Thirdly, AM-356 inhibited

lower sperm counts
than nonsmokers."

stance in marijuana), as well as to

ever, once removed from the

tight binding of sperm to the

Collaborating on

anandamide (a cannabinoid-like

seminal plasma and exposed for

egg's zona. "Failure of sperm to

the research were Drs.

unexplained

molecule, or endocannabinoid,

several hours to secretions with-

bind tightly to zonae is predic-

Robert Picone and

types of

normally produced in the body)

in the female reproductive tract,

tive of fertilization failure for in

Alexandros Makri-

may regulate sperm functions re-

sperm become "capacitated"

quired for fertilization in humans.

and can fertilize eggs in vivo, or

vitro fertilization," says Burkman.
"Defects in endocannabinoid-

yannis of the University of Connecticut;

The study, led by Herbert

by incubation in appropriate
culture media in vitro.

signaling may be responsible for

Jack Lippes of UB; Mary C.

Schue!, PhD, professor in pathol-

certain currently unexplained

Mahony of Eastern Virginia

ogy and anatomical sciences, and

"We know that sperm capa-

Medical School; and Andrea

Lani Burkman PhD, assistant
professor of gynecology-obstet-

citation and fertilizing potential
are tightly regulated within

types of infertility," Schue! says.
"Conversely, endocannabinoidsignaling in reproductive tracts

Giuffrida and Daniele Piomelli
of the University of California

rics, presents the first evidence

female reproductive tracts, "

that anandamide exists in

Burkman says. "We also know

may provide potential targets for
future development of novel

-LO IS BAKER

human seminal plasma, mid-

that the cannabinoid receptor

cycle oviductal fluid and follicu-

found in the human brain is ex-

lar fluid. Sperm are normally
exposed to these fluids as they

pressed in the human testis, and
that anandamide is produced in

travel from the vagina to the site

mammalian testes and uteri."

of fertilization in the oviduct.

Capacitated sperm exhibit a

The study also shows that human
sperm contain cannabinoid re-

characteristic pattern of vigorous
swimming called hyperactivated

ceptors, and that anandamide

motility. After binding to a specific protein in the egg's surface

and THC regulate the sperm's
"These results suggest that

coat (zona pellucida), capacitated
sperm undergo the acrosome re-

natural endocannabinoid signal-

action, a secretory event in sperm

ability to fertilize eggs in vitro.

,.'

drugs for reproductive medicine.

activate these receptors. A sub-

ing regulates sperm functions in
humans-findings with implications for human reproduction
and drug abuse," Schue! says.
In 1991, a cannabinoid receptor gene was cloned from a

currently

infertility,"
Schuel says.

at Irvine.

that releases enzymes that enable
sperm to penetrate zonae during
fertilization. The current study
found that an anandamide analog (AM-356) and THC affect the
following processes in humans.

:

i

..•

....

First, a low concentration of

human brain, which suggested
that the body must produce its

AM-356 stimulated hyperacti-

own chemical version ofTHC to

vated motility while slightly higher

lani Burkman PhD, and Herbert Schuel, PhD.

Spring

2 001

Bu ffalo Physici an

33

�DEVELOPMENT

N

E

w s

(ve~ G"ft Vi ato School's future
By Li nda J . Co rde r. PhD. CFRE

and Biomedical Sciences received $10.8 million in gifts
and grants. About two-thirds of the total represented
grants awarded competitively by foundations, corporations and nonprofit organizations to outstanding
faculty researchers.
Members of the James Platt White Society account
for the vast majority of the remainder, approximately
$3.7 million. This figure represents current gifts, contributions to endowments, bequests and other estate gifts.
When I see the tremendous difference that these gifts
make to the quality of life for those who study, teach,
conduct research and see patients, saying "Thank you"
seems hardly enough ... I wish you could walk the halls
of our school, our affiliated hospitals, our laboratories
and student study areas with me. You would recognize
many signs of your philanthropy at work.
"Scholarships" is the designation for many gifts. We made proTHIS FUND SUPPLE·
gress this year, but increasing both
MENTS SCHOLARSHIP
the size and number of scholarAWARDS, PAYS
ships remain a high priority. CurTRANSPORTATION
rently our medical students gradCOSTS FOR STU·
uate owing, on average, about
DENTS TO PRESENT
$80,000 in education loans. For
RESEARCH RESULTS
the school to enroll its most
AND UNDERWRITES
promising applicants, it simply
RECEPTIONS FOR
needs more scholarship funds.
DISTINGUISHED
Members of the Society underALUMNI WHO RE·
wrote several lectures this year.
TURN TO TALK WITH
The Department of Pathology
STUDENTS ABOUT
launched a lecture in memory of
THEIR CAREERS.
Dr. Kornel Terplan. Students
heard inspiring lectures dealing
with the "art of medicine" during
their first- and second-year orientation sessions. Surgery residents participated in the 11 th annual
Winfield Butsch Lectureship with an internationally
renowned surgeon.

The medical student Professionalism Committee
finalized the Code of Conduct. It was overwhelmingly
approved by students, the Faculty Council and Dean's
Executive Committee. A member of this Society
underwrote costs for it to be printed on
attractive stock, worthy of the content,
and distributed without cost to students.
The first recipient of the Frawley Resident Research Award received laboratory
support for his research in cardiac pathology, cardiac cell biology and integrative
physiology. He worked under the guidance
of Dr. John Canty, holder of the Rekate
Chair in Cardiovascular Disease, an endowed position
supported by the Rekate and Boardman Endowments.
Many Society members gave to the school's general
fund. These contributions provide flexibility to Dean
Wright to respond to opportunities that arise serendipitously. This fund supplements scholarship
awards, pays transportation costs for students to present research results and underwrites receptions for
distinguished alumni who return to talk with students
about their careers. Faculty recruitment costs, often
not fully covered by budgeted funds, may be supplemented by this fund. A small proportion of overall
philanthropy, the general fund remains an important
component of the budget.
Please help us spread the word regarding the importance of private support. Although state-assisted, the
school receives only about 12.5 percent of its budget
directly from New York State. Thus, every bit of gift
money is vital to our school's future.
Development staff members, working in conjunction with alumni, faculty and department chairs, some
emeritus faculty members, most importantly, the dean
and campaign volunteers who believe in this work, are
responsible for encouraging private philanthropy.
We want you to know that gifts are used precisely as
" DE V EL O PME NT"

l 1ffala Pbysician

Spring

2001

CON TI NUE D

ON

P AG E 4 4

�}ANUARY

the

1 ,

2 0 0 0 - D

E

c

E J\1 B E R

3 1 ,

2 0 0 0

Society
When cumulative contributions reach $50,000 or an irrevocable deferred gift is completed for
$100,000 or more, a couple or individual is granted lifetime membership in the ]ames Platt
White Society. Combinations of outright and deferred gifts in appropriate proportions may

also be the basis oflifetime membership. Names of Founders' Circle members are repeated
in the annual category in any year that they make a new gift to the school.

Founders' Circle
UB's fo unders-pri maril y
physicians and attorneysenvisio ned a school to trai n
studen ts for service to the
commun ity. The Society's
Founders help to actual ize
that vision by providi ng a
genero us base of support
fo r programs and activities
that enri ch th e academi c
enviro nment and enhance
medical training.

Dr. Willard H. Boardman '44 &amp;
Mrs. Jean E. Boardman '48
Winter Park, FL
Dr. William M. Chardack

Buffalo, NY
Mrs. June M. Alker

James Platt
White, MD,

(1811-18811
was instrumental
in founding UB's
medical school in

1846.

W illiamsville, NY
Charles D. Bauer MD '46 &amp;
Mrs. Mary Bauer

Williamsville, NY
Dr. Ralph T. Behling '43

San Mateo, CA
Dr. Willard H. Bernhoft '35 &amp;
Mrs. Clarice L. Bernhoft

Snyder, NY

Dr. Thomas F. Frawley '44 &amp;
Mrs. Marigrace Frawley

Gulfstream, FL

Chesterfield, MO

Dr. Joseph A. Chazan '60 &amp;
Mrs. Helen Chazan

Mrs. Christine Gretschel
Genner

Providence, Rf

Potomac, MD

Mr. DuVal Cravens
(deceased! &amp; Mrs. Annette
Cravens

Mr. John H. Goodwin Jr.

Buffalo, NY
Dr. Kenneth M. Alford '37 &amp;
Mrs. Joan W. Alford

Dr. Richard J. Nagel '53 &amp;
Mrs. Florence T. Nagel

Mrs. Catherine Fix

Martinsburg, WV

Mr. Donald L. Davis &amp; Mrs.
Esther P. Davis

Clarence, N Y
Dr. Pasquale A. Greco '41 &amp;
Mrs. Lois J. Greco

Buffa lo, NY

Williamsville, NY
Dr. Max Doubrava Jr.

W illiamsville, NY

Mrs. Marjorie B. Eckhert

Dr. Thomas J. '61 and Mrs.
Barbara L. Guttuso

Buffalo, NY

East A m herst, NY

Ms. Rose M. Ellerbrock

Dr. Eugene J. Hanavan Jr. '41

Willia msville, NY

Buffa lo, NY

Dr. George M. Ellis Jr. '45 &amp;
Mrs. Kelly Ellis

Mrs. Morris Lamer

Connersville, TN
Mrs. Grant T. Fisher
Palm Beach, FL

East Aurora, NY
Dr. Albert C. Rekate '40 &amp;
Mrs. Linda H. Rekate '71

William sville, NY
Dr. Elizabeth P. Olmsted
Ross '39

Buffa lo, NY
Ms. Thelma Sanes

Dr. Glen E. Gresham &amp; Mrs.
Phyllis K. Gresham '85

Las Vegas, NV

Orchard Park, NY
Dr. Richard B. Narins '63 &amp;
Mrs. Ellen B. Narins

Williamsville, NY
Dr. Robert J. Smolinski '83 &amp;
Dr. Claudia D. Fosket '85

O rchard Park, NY
Dr. Janet H. Sung &amp;
Mr. John J. Sung

Clarence, NY
Dr. Philip B. Wels '41 &amp; Mrs.
Elayne G. Wels

Williamsville, NY

New York, NY
Dr. Eugene R. Mindell &amp; Mrs.
June A. Mindell

fOUNDERS' C IR CLE, CONT'D

Buffa lo, NY

Spring

200 1

Buffalo Physiciaa

35

�DEVELOPMENT

just as a department chair
leads a program, donors of
leadership gifts in the range
of $10,000 to $24,999 are
given special recognition.

Mrs. Mollie Holtzman
Bergman
Hollywood, FL
Dr. &amp; Mrs. Ernest Beutner
Eggertville, NY
Dr. Carl V. Granger
Buffalo, NY
Philip D. Morey M.D. '62 &amp;
Mrs. Colleen Morey
Williamsville, NY
Dr. Edward Shanbrom '51 &amp;
Mrs. Helen Shanbrom
Santa Ana, CA

The dean is the school's
leader. Every leader depends on a small circle of
associates who help bring
the organization's vision
into reality. Individuals or
couples qualify as members
in the Dean's Circle with
generous gifts of $25,000
or more during the calendar year.

Mr. Donald L. Davis &amp; Mrs.
Esther P. Davis
Williamsville, NY
Dr. Max Doubrava Jr. '59
Las Vegas, NV
Dr. Lawrence Golden '46 &amp;
Mrs. Nancy Golden '48
Eggertsville, NY
Dr. Albert C. Rekate '40 &amp;
Mrs. linda H. Rekate '71
Williamsville, NY

Dr. Eugene J. Zygaj '50
Lancaster, NY

A strong faculty is central to
a great university. Likewise,
central to the future of our
school is the dedication of a
cadre of supporters whose
annual gifts range from
$5,000 to $9,999.

Mrs. June M. Alker
Williamsville, NY
Charles D. Bauer, MD '46 &amp;
Mrs. Mary A. Bauer
Williamsville, NY
Dr. Joseph G. Cardamone '65
&amp; Mrs. Susan G. Cardamone
Eden, NY

Dr. Morton A. Stenchever '56
Mercer lsland, WA

Drs. Michael and Laura
Garrick
Getzville, NY

Dr. Martin C. Terplan '55
San Francisco, CA

Dr. Waun Ki Hong
Houston, TX
Mr. Fred K. Kurata &amp; Mrs.
Lynn W. Kurata
Santa Monica, CA

36

I u II a I o Pb ys i c i a n

E

w

Dr. Gordon R. Lang '62
Chicago, IL

PLATT SOCIETY, CONT'O

Annual donors of $1,000*
or more are granted membership in the james Platt
White Society.
Annual memberships in
the appropriate circle within the james Platt White
Society are granted for one
year, beginning january I
(for gifts received the prior
calendar year).
The roster of the fames
Platt White Society "Class
of 2000" follows.

N

Spring

2 0 0 1

Dr. Shedrick H. Moore '55
Costa Mesa, CA
Dr. John C. Newman
Lewiston, NY
Dr. Charles S. Tirone '63 &amp;
Mrs. Anne R. Tirone '94
Williamsville, NY
Dr. James J. White Jr. '69
Buffalo, NY

Scholars· Circle
One strength of outstanding institutions is the caliber
of those who study there.
Scholars within the james
Platt White Society have
made gifts to the school totaling $1,000 to $2,499 during the past year. Those
marked with an asterisk (*)
are young scholars, graduates of the last decade, who
qualify with gifts of $500
to $999.

'"'·c e
Fellows within the school are
recognized for added depth
they bring to postgraduate
study. Fellows are honored
for gifts that total $2,500 to
$4,999.
Dr. &amp; Mrs. Charles A. Bauda
'42
Boynton Beach, FL

Dr. C. John Abeyounis
Williamsville, NY
Dr. Kenneth M. Alford '37 &amp;
Mrs. Joan W. Alford
Buffalo, NY
Dr. Kenneth Z. Altshuler '52
&amp; Mrs. Ruth Altshuler
Dallas, TX

Dr. Willard H. Boardman '44
&amp; Mrs. Jean Boardman '48
Winter Park, FL
Dr. Lawrence B. Bone '73
Orchard Park, NY
Dr. Dennis L. Bordan '70
Port Washington, NY
Dr. Suzanne F. Bradley '81
Whitmore Lake, Ml

Dr. Martin '72 &amp; Geri Brecher
Amherst, NY
Dr. Robert A. Brenner '59
Moravia, NY
Dr. Harold Brody '61
Getzville, NY
Dr. James B. Bronk '81 &amp;
Mrs. Suzanne Bronk
Napa, CA
Dr. August A. Bruno Sr. '51
Buffalo, NY
Dr. David P. Buchanan '48
Hillsborough, CA

Dr. Hossein Amani
Ontario, Canada

Dr. William M. Burleigh '67
Rancho Mirage, CA

Dr. Melvin M. Brothman '58
Snyder, NY

Dr. WilliamS. Andaloro '45
Caledonia, NY

Dr. Washington Burns Ill '61
Berkeley, CA

Dr. Jennifer L. Cadiz '87
Lemoyne, PA

Dr. Mark Anders
Buffalo, NY

Dr. Charoen &amp; Dr.
Charlearmsee Chotigavanich
Thailand

Dr. Douglas Armstrong
Buffalo, NY

Dr. Evan Calkins &amp; Dr.
Virginia Calkins
Hamburg, NY

Dr. Robert Gillespie '74 &amp;
Mrs. Kathleen Gillespie
Buffalo, NY
Dr. Hak J. Ko
Buffalo, NY
Dr. Robert L. Malatesta '60
Warren, N]
Dr. Susan V. McLeer
Buffalo, NY
Dr. Nancy H. Nielsen '76
Orchard Park, NY
Dr. Thomas P. O'Connor '67
&amp; Mrs. Sandra S. O'Connor
East Amherst, NY
Dr. Robert J. Smolinski '83 &amp;
Dr. Claudia D. Fosket '85
Orchard Park, NY

Dr. J. Bradley Aust Jr. '49
San Antonio, TX
Dr. George Bancroft '81 &amp;
Mrs. Susan K. Bancroft '79
Hamburg, NY
Dr. Elizabeth P. Barlog '82 &amp;
Dr. Kevin Barlog '82
Amherst, NY
Dr. Jared C. Barlow Sr. '66 &amp;
Mrs. Barabara Barlow
Grand Island, NY
Dr. Paul D. Barry '71
Arlington, VA
Dr. Richard A. Berkson '72 &amp;
Mrs. Andrea Berkson
Rancho Palos Verdes, CA
Mr. Sheldon M. Berlow
Buffalo, NY

Dr. David T. Carboy '63 &amp;
Mrs. Jacqueline G. Carboy
Lincroft, Nj
Dr. Nicholas C. Carosella '54
Appleton, NY
Dr. Yung C. Chan '73
Draper, VA
Dr. Norman Chassin '45 &amp;
Mrs. Charlotte S. Chassin
Williamsville, NY
Dr. Charles Kwok·Chi Chow &amp;
Mrs. Patricia Chow
Hong Kong

Dr. Bernice S. Comfort·Tyran '58
Los Altos, CA
Dr. Donald P. Copley '70 &amp;
Mrs. Andrea Copley
Amherst, NY
Dr. Linda J. Corder
Buffalo, NY

Dr. Irving Sterman '64 &amp;
Mrs. Gail K. Sterman
jacksonville, FL

Dr. Michael E. Bernardino &amp;
Mrs. Joan Bernardino
Buffalo, NY

Mr. Haskell Stovroff
Buffalo, NY

Dr. Beverly P. Bishop '58
Snyder, NY

Dr. Julia Cullen '49
Buffalo, NY

Mr. James I. Stovroff
Buffalo, NY

Dr. Theodore S. Bistany '60
Buffalo, NY

Dr. Daniel E. Curtin '47 &amp;
Mrs. Elaine Curtin
Orchard Park, NY

Dr. J. Steven Cramer
East Amherst, NY

�E VE R Y LEADE R DEPE

DS 0

HELP BR I NG T H E ORGA

A SMALL CIRCLE OF ASSOC I ATES W H O

I ZAT I ON ' S V I SIO

I NTO R EALITY .

Dr. David R. Dantzker '67 &amp;
Mrs. Sherrye Dantzker

Dr. William A. Fleming '64 &amp;
Dr. Beth D. Fleming '67

Dr. John H. Hedger '75 &amp;
Mrs. Sandra Hedger

Dr. Paul B. Karas '87 &amp; Mrs.
Donna Karas

Dr. Mark J. Lema '76 &amp; Mrs.
Suzanne Lema

Roslyn, NY

Buffalo, NY

Salisbury, MD

Buffalo, NY

East Amherst, NY

Dr. Roger S. Dayer '60 &amp; Dr.
Roberta A. Dayer '72

Dr. Andrew J. Francis '84

Dr. Reid R. Heffner Jr. &amp; Mrs.
Elenora M. Heffner

Dr. Julian R. Karelitz '68 &amp;
Dr. Mayenne A. Karelitz

Dr. Harold J. Levy '46 &amp; Mrs.
Arlyne Levy

Buffalo, NY

Carson City, NV

Amherst, NY

Dr. William J. Hewett '61

Dr. Mahito Kawashima

West Hartford, CT

Japan

Dr. David C. Lew &amp; Mrs. June
K. Lew

Dr. Fredric M. Hirsh '73 &amp;
Mrs. Donna A. Hirsh

Dr. John H. Kent '55

Buffalo, NY

Coram, NY
Dr. Neal W. Fuhr '52

Dr. Gerard J. Diesfeld '60

Arcade, NY

Williamsville, NY
Dr. Penny A. Gardner '69

Ronald I. Dozoretz M.D. '62

Falls Church, VA
Dr. Robert Einhorn '72

North Brunswick, N]
Dr. lillian M. EngasserRowan'45

Chatsworth, CA
Dr. Domonic F. Falsetti '58

Lewiston, NY
Dr. Leon E. Farhi &amp; Mrs.
Haya Farhi

Eggertsville, NY
Mr. Kevin Feor '80 &amp; Mrs.
Elizabeth A. Feor '78

Webster, NY
*Dr. Amy E. Ferry '94

Bethlehem, PA
Dr. Helen Marie Findlay '78 &amp;
Dr. Albert Schlissennan '77

Eggertsville, NY
Dr. Marc S. Fineberg

Williamsville, NY
Dr. Susan Fischbeck '82 &amp;
Dr. Patrick T. Hurley '82

East Concord, NY
Dr. Jack Fisher '62

La jolla, CA

Los Altos, CA
Dr. Ronald F. Garvey '53

Tyler, TX
Kenneth L. Gayles, M.D.
Amherst, NY
Dr. Carmen D. Gelormini '50

Syrawse, NY
Dr. Michael Goldhamer '64

San Diego, CA
Dr. Peter H. Greenman '80

Fairfax Station, VA
Dr. Glen E. Gresham &amp; Mrs.
Phyllis K. Gresham '85

Williamsville, NY
Dr. Robert T. Guelcher '60 &amp;
Mrs. Elizabeth Guelcher

Erie, PA
Dr. Thomas J. Guttuso Sr. '60
&amp; Mrs. Barabara Guttuso

East Amherst, NY
Dr. Robert Joseph Hall '48 &amp;
Mrs. Dorothy N. Hall

Houston, TX
Dr. Christopher Hamill '89

Buffalo, NY
Dr. Donald A. Hammel '60

Ravena, OH

Dr. Thomas D. Flanagan '65 &amp;
Mrs. Grace Flanagan '70

Williamsville, NY

n

This society honors Genera l Edmund Hayes, an
in ternat io na lly reno wn ed d es igner of bridges
who bequea thed nea rly
$390,000 to UB in 1923.
Over the years, a growing
number o f friends a nd
alumni o f UB's School of
Medicine and Bio medical
Sciences have joined the
Ed m und H ayes Society
by including the school
in their estate plan. If you
are interested in becomin g a m e m ber of th e

Dr. Seymour J. Liberman '61

Buffalo, NY

Dr. John M. Hodson '56

Dr. Kenneth K. Kim '65 &amp;
Mrs. Susan W. Kim

Williamsville, NY

Clinton, NY

Mr. Paul F. Hohenschuh &amp;
Dr. Marjorie E. Winkler

Dr. Francis J. Klocke '60

Burlingame, CA
Dr. Hilton R. Jacobson '45

Shaker Heights, OH
Dr. Marshall A. Lichtman '60

&amp; Mrs. Alice Jo M. Lichtman
Rochester, NY

Chicago, IL

Dr. Hing-Har Lo '74

Dr. Robert A. Klocke '62 &amp;
Mrs. Barbara Klocke

Dr. Alice Challen Lo Grasso '37

Blacksburg, VA

Lakewood, NY

Williamsville, NY

Alameda, CA

Robert M. Jaeger, M.D. '47

Mr. Tetsuri Kondo

Allentown, PA

Japar1

Dr. Gerald L. Logue &amp; Mrs.
Joelle Logue

Dr. Herbert E. Joyce '45 &amp;
Mrs. Ruth Marie Joyce

Dr. Joseph M. Kowalski '93

Lockport, NY
Mr. Arthur H. Judelsohn

Buffalo, NY
Mr. Chan Y. lung &amp; Mrs.
Sooja Y. lung

East Amherst, NY
Dr. Wendy A. Kaiser '85 &amp;
Dr. Roger E. Kaiser Jr. '79

Clarence, NY
Dr. James R. Kanski '60 &amp; Dr.
Genevieve W. Kanski '84

Eggertsville, NY
Dr. Robert E. Kaplan '81

Buffalo, NY

Williamsville, NY

Dr. Thomas A. Lombardo Jr. '73
&amp; Mrs. Donna M. Lombardo
East Aurora, NY

Amherst, NY
Dr. Kenneth Krackow

Williamsville, NY
Dr. Jacob S. Kriteman '67

Danvers, MA
Dr. Robert B. Kroopnick '72

Pikesville, MD

*Dr. David R. Ludwig '90

Williamsvillie, NY
Dr. Frank A. Luzi '88 &amp; Dr.
Lori Luzi '88

Clarence, NY

Dr. Ivan W. Kuhl '45

Dr. James R. Markello '61

Wimberley, TX

Eden, NY

Dr. Marie Leyden Kunz '58 &amp;
Dr. Joseph L. Kunz ' 56

Lockport, NY
Dr. Weerachai Ladakom '91

Bangkok
Dr. Andre D. Lascari '60

Poestenkill, NY

Williamsville, NY

T

Okahumpka, FL

Dr. John M. Marzo '86

Buffalo, NY
Dr. Conrad May '81

Kensington, MD
Dr. Brian McGrath

Buffalo, NY

Dr. Ronald F. Garvey

Dr. Karl L. Manders

Dr. John T. Cangelosi

Mr. John H. Goodwin, Jr.

Dr. Benjamin E. Obletz

Dr. Stanley B. Clark

Dr. Adele M. Gottschalk

Dr. Elizabeth P. Olmsted
Ross

H ayes Society, you m ay
con tact the Planned Giving Office at 716-645-33 12.
O r, if you have made similar plans and do not see
yo ur na m e o n thi s lis t,
please call Mary Glenn in
the UB O ffi ce o f Develo pm ent, toll -free, at 1-877826-3246 so that we may
in cl ud e yo u in sp ec ia l
events d uring the year and
honor you in futu re recogn itio n lists.

Dr. Charles A. Bauda

Dr. Frances R. Abel

Mrs. Grant T. Fisher

Dr. linda J. Corder

Dr. Pasquale A. Greco

Dr. Julia Cullen

Dr. Glen E. Gresham

Dr. Thomas G. Cummiskey

Dr. Eugene J. Hanavan, Jr.

Dr. Richard A. Rahner
Dr. Albert C. Rekate
Dr. Myron G. Rosenbaum

Mr. Edward L. Curvish, Jr.

Dr. David M. Holden

Dr. Leonard S. Danzig

Dr. Hilliard Jason &amp;
Dr. Jane Westberg

Dr. Daniel S. P. Schubert

Dr. Richard F. Kaine

Dr. Albert Somit

Dr. J. Walter Knapp

Dr. Eugene M. Teich

Dr. Melvin B. Oyster
Ms. Rose M. Ellerbrock
Dr. George M. Ellis, Jr.

Dr. Kenneth M. Alford

Dr. Jack C. Fisher

Mrs. June M. Alker

Dr. Lance Fogan

Miss Thelma Sanes

Dr. Harold J. Levy

Dr. Pierce Weinstein

Dr. Sanford H. Levy

Dr. John R. Wright

Dr. Milford &amp; Dione
Maloney

Dr. Wende W. Young

Spring

2001

lulf alo Physiciaa

37

�DEVELOPMENT

E

w

Dr. Margaret W. Paroski '80

Dr. David S. Schreiber '69

Dr. James C. Tibbetts '64

Buffalo, NY

Westwood, MA

Sturgeon Bay, WI

Dr. Harry L. Metcalf '60 &amp;
Dr. Kaaren Metcalf '78

Dr. Robert J. Patterson '50 &amp;
Mrs. Patricia M. Patterson

Dr. Joseph I. Schultz '57 &amp;
Mrs. Yolanda Schultz

Dr. Bradley T. Truax ' 74

Williamsville, NY

Snyder, NY

San Pedro, CA

Dr. Merrill L. Miller '71

Dr. Norman L. Paul '48

Dr. Fred S. Schwarz '46

Hamilton, NY

Lexington, MA

Buffalo, NY

Dr. David P. Mindell &amp; Mrs.
Margaret H. Mindell

Dr. John H. Peterson '55

East Aurora, NY

Dr. Roy E. Seibel Sr. '39 &amp;
Mrs. Ruth Seibel

SCHOLARS' CIRCLE, CONT'D

Ann Arbor, MI

Eggertsville, NY

Lewiston, NY
Dr. John A. Tuyn '60

Williamsville, NY
Dr. Hugh D. VanLiew &amp;
Dr. Judith B. Van Liew
Dr. Alvin Volkman '51

North Hills, NY

Dr. Molly R. Seidenberg '53

Georgetown, DE

Buffalo, NY

Rochester, NY

Dr. Arthur M. Morris '65

Dr. Matthew Phillips '91

Dr. Arthur M. Seigel ' 70

Dr. Richard D. Wasson '58 &amp;
Mrs. Janet Wasson

River Forest, IL

Buffalo, NY

Guilford, CT

Holiday, FL

Dr. John A. Moscato '68 &amp;
Dr. Beth A. Moscato '96

Mr. Edwin Polokoff

Dr. Elizabeth G. Serrage '64

Dr. Arnold Wax ' 76

Boca Raton, FL

Cape Elizabeth, ME

Hendersor1, NV

Dr. Anthony V. Postoloff '39

Mr. Eugene M. Setel

Williamsville, NY

Buffalo, NY

Dr. Charlotte C. Weiss '52 &amp;
Dr. Hyman Weiss

Manhasset, NY
Dr. Arthur W. Mruczek Sr. '73

Dr. Kenneth John Raczka &amp;
Mrs. Rita Raczka

Medina, NY

Amherst, NY

Dr. Richard L. Munk '71

Ms. Katharine B. Rahn

Sylvania, OH

Arlington, MA

Dr. Masao Nakandakari '55

Dr. John Y. Ranchoff '52

Dr. John B. Sheffer '47

Williamsville, NY
Dr. Peter E. Shields '79

Tonawanda, NY
Dr. Timothy S. Sievenpiper '68
&amp; Mrs. Karen S. Sievenpiper

Greenville, NC

Highland Park, NJ

Carlsbad, CA

East Aurora, NY

John B. Neeld, M.D.P.C.

Dr. Bert W. Rappole '66 &amp;
Mrs. Mary Helen Rappole

Dr. &amp; Mrs. Edward H. SiiMIOIIS
Williamsville, NY

Dr. Richard G. Williams '80

jamestown, NY
Dr. Frederic D. Regan '45

Dr. Ralph M. Obler '52 &amp;
Mrs. June M. Obler '49

Los Angeles, CA
Dr. Yasuyo Ohta

Japan
Dr. Kathleen O'Leary '88 &amp;
Mr. Michael J. Collins '90

Buffalo, NY
Dr. Albert J. Olszowka '58 &amp;
Dr. Janice S. Olszowka

Boca Raton, FL
Dr. Frank T. Riforgiato '39 &amp;
Mrs. Mary Cecina Riforgiato

Buffalo, NY
Dr. John G. Robinson '45 &amp;
Mrs. Pauline H. Robinson '67

Williamsville, NY

Dr. Bernhard J. Rohrbacher '83
Getzville, NY
Dr. Richard R. Romanowski '58
Buffalo, NY

Dr. James M. Orr '53

Dr. Jeffrey S. Ross ' 70

Gallipolis, OH

Lebanon Springs, NY

Nanuet, NY

Dr. Albert Somit

Encinitas, CA
Dr. John J. Squadrito '39

Albany, NY
Dr. Philip M. Stegemann '82

Orchard Park, NY
Dr. William C. Sternfeld '71

Sylvania, OH
Mrs. Gloria Stulberg

Orchard Park, NY
Dr. John R. Wright &amp; Mrs.
Deanna P. Wright

Williamsville, NY
*Dr. Shih-Ping Yang '93

Dr. Edwin A. Salsitz '72

Maitland, FL

New York, NY

Mr. Chun-Sik Park &amp; Mrs.
Younghae K. Park

Dr. Arthur Schaefer (deceased)

Dr. Sylvia W. Sussman '60

Allentown, PA
Hideo Suzuki

Holland, NY
Dr. Wende W. Young '61

Dr. Meyer lllwchun 'XI
and Mrs. Ann S. Rlwchun

Malden, MA

Dr. Warren M. Zapol

Boston, MA
Dr. Franklin Zeplowitz '58 &amp;
Mrs. Piera Zeplowitz

Buffalo, NY

&amp; Mrs. Elizabeth Ann Schaefer
Snyder, NY

Dr. Wayne C. Templer '45

Dr. Adolphe J. Schoepflin '45

Mr. Fritz Terplan

Ada, OK

San Francisco, CA

Walnut Creek, CA
Dr. Israel Ziv

Williamsville, NY

Ph ysici an

Spring

2001

Mr.WafterMazal

*Ms. Sanda Yu '95

Dr. David C. Ziegler '64 &amp;
Mrs. Susan D. Ziegler

Latrobe, PA

Dr. Clan A. March '07

Canandaigua, NY

japan
Corning, NY

Ms. V'll'linia A. lames

Mrs. Grace S. Mabie

Carmel, IN

Tonawanda, NY

The following individuals left generous
bequests or made arrangements for the
school to receive gifts
from testamentary
trusts. Gifts from the
individuals listed below were received
during 2000.
Miss Ruth v. Hewlett '30

Dr. Michael A. Sullivan '53

Williamsville, NY

Williamsville, NY

Taiwan

Buffalo, NY
Williamsville, NY

Dr. Marvin Z. Kurian '64 &amp;
Mrs. Eleanor Kurian

Dr. Gregory E. Young '77 &amp;
Mrs. Diane Young

Buffalo, NY

Dr. Paul A. Palma '73

lul f a le

Lewiston, ME
Dr. Robert G. Smith '49

Clearfield, PA
Mr. Ralph C. Wilson Jr.

Dr. Heun Y. Yune &amp;
Mrs. Kay K. Yune

Dr. Albert G. Rowe '46

Dr. John S. Parker '57 &amp;
Mrs. Dorris M. Parker

Dr. Richard A. Smith

Orlando, FL

Mr. James J. Rosso '76 &amp;
Mrs. Cheryl Rosso

Dr. Charles V. Paganelli Jr. &amp;
Mrs. Barbara Paganelli

Seoul, Korea

Orchard Park, NY

Savannah, GA

Amherst, NY

Dr. Marvin G. Osofsky '59

Dr. James A. Smith ' 74

Dr. John L. Butsch
Buffalo, NY

Dr. Gary J. Wilcox '73

Fairview Park, OH

Dr. Tomoe Nishimaki

Ms. Janet F. Butsch

Aurora, CO

Buffalo, NY

Honolulu, HI

Japan

Dr. David W. Butsch

Montpelier, VT

Dr. Paul H. Wierzbieniec '74
&amp; Ms. Ellen Wierzbieniec

Dr. Charles E. Wiles '45

Atlanta, GA

A few individuals and couples were granted multiyear memberships based
on generous gifts made between 1989 and 1993.

Dr. Robert Bernot '60 &amp; Mrs.
Carol Bernot

Dr. James F. Phillips '47 &amp;
Mrs. Marcella Phillips

Orchard Park, NY

Special Members

Barnstable, MA

Dr. Maynard H. Mires Jr. '46

Dr. John D. Mountain '33

38

N

Mrs. TModosia H.

SlicllneJ '28
Mrs. Ethel Wlmbelty

We have made every
effort to ensure accuracy in these lists. If
you have any questions or corrections,
call Mary Glenn tollfree
or
or e-mail her at
glenn@acsu.butfalo.edu.

�Dear Fellow Alumni,
was held the last weekend in April and

1 Q

was a tremendous success, with over 300 University at Buffalo School of Medicine and Biomedical
Sciences' alumni attending with their families. Be sure to look for a full report on the weekend's events
in the summer issue of Buffalo Physician, which, among other things, will feature the
four alumni chosen by the Medical Alumni Association Board to receive this year's
achievement awards: Marcella F. Fierro, MD '66, Wendy W. Logan-Young, MD '61,
Nancy H.

ielsen, MD '76, and Morton A. Stenchever, MD '56.

As my year of serving as president of the Medical Alumni Association comes to a
close, I can tell you that it has been both a privilege and an honor to serve in this
capacity and to have had the opportunity to meet so many interesting and outstanding
members of our UB Alumni Association. At this time, I would like to thank a few people who help
make this organization run as smoothly and effectively as it does.
Bertram Portin, MD '53, our assistant dean for Alumni Affairs, is a tremendous source of
support and information, as is Dr. Jack Richert, former associate dean for Alumni Affairs,
who has served on the board this year at my request. Jack has also helped with his tremendous
knowledge of the history of the organization and the medical school. Mrs.

ancy Druar, who serves

as our administrative assistant, is certainly the glue that holds this organization together and
without Nancy's help, we wouldn't have any of the successful programs that we have today.
I also would like to thank some of our fellow Alumni Association board members: Richard
Collins, MD '83, who has served as past president, Patricia Duffner, MD '72, who served this year as
vice-president, Colleen Mattimore, MD '91, who will be the next vice president, and Stephen
Pollack, MD '82, who will be the next treasurer and secretary.
I would be remiss if I did not mention one more time that we are still looking for many more
lifetime members, and we hope that you, as alumni, will find it in your hearts to support our school
in this manner.
Once again, I thank you for allowing me to serve as your president.

II , MD
President, Medical Alumni Association

jOHN j . BODKIN

Spring 2001

luffal1 Physician

39

�CLASSNOTES

1940s
William Herman Bloom,
MD '48, has been elected

to Who's Who in Medicine and Healthcare, as
well as Who's Who in
Science and Engineering
and Who's Who in the
World. He recently published After All, It's Only
Brain Surgery (available
in bookstores ISB l56167-573-3; publisher,
Noble House).

Michael Genco, MD '58,

writes: "Ann and I are
enjoying retirement. We
have moved to a condo
at 600 Main Street in
downtown Buffalo, NY,
14202." E-mail address
is: mgencobuf@aol.com.

1960s
Dick Eggleston, MD '62,

writes, "Hi, I retired
from Ford Motors at the
end of2000. We just
completed a home in
Hamilton, MT. I will
be hiking, learning to
fly fish and using my

camera. In addition, I
have accepted a parttime
position at Marcus Daly
Hospital in Hamilton."

1970s
Howard R. Goldstein,
MD '74, writes: "Judy and
I are still living in Cherry
Hill, NJ. I'm in an eightman urology practice
and am very happy. Our
children: Lee is a firstyear surgery resident at
the Hospital of University of Pennsylvania
(MD, Yale Medical
School); Lauren is a

the next four years. These
included tours of duty in

surgery, thanks to a surgi-

In 1974, I was in·

'46, FPCS, writes from

cal residency while in the

ducted as a Fellow in the

Santa Barbara, CA:

Philadelphia, Washington,

Navy. Because of being in a

Philippine College of Sur-

Greetings from - of
the members of the

DC, the USNAS in the Phil-

"goiter belt," I seemed to

geons. As the years went

ippines, and An-

by, my role gradually

short-term help to sister

class of '46. In lieu of

napolis before

shifted to that of men·

mission hospitals in tiYe

Uncoln D. Nelson, MD

a healthy body) but lose
his soul?'
Since retirement we
haYe continued to glye

my being able to attend

discharge from

tor for young Filipino

foreign countries:

the reunion In April, I

actiYe duty in

doctors. When we re-

Bangladesh, Amazonas

will write this note about

'51. Six months

tired from full-time

Brazil, Togo, the Gambia

our life's work. I say

thereafter we

duty with our Mission

in West Africa and a
clinic in the Ukraine. We

'our' since my life's

were back in the

lthe Association of

partner, Lenore Butts

PhHipplnes under

Baptists for Wortd

plan to continue doing

Nelson, RN, became my

a HeaYenly Com-

EYangelism, Inc.) we

so as long as the Lord

bride in '44 and has re-

mander In Chief.

malned my closest friend

For the next

left three of these

keeps us in good health.

hospitals In the

We are grateful for the

and colleague in our

35 years, God

capable hands of an

training years at UB and

medical missionary work

enabled us to

all-Filipino staff

thank our mentors there.

eYer

since our training

years In Buffalo.

establish three rural

major in thryoidectomies

continuing the care of the

We hnen't piled up

mission hospitals and as-

and deYeloped a technique

total patient: body, soul

much of this wortd's

and spirit.

goods, but the remu-

sist in a fourth. These each

of doing them under

In a ciYIIIan hospital in

became general hospitals

regional block anesthesia.

Hackensack, NJ, in '46-

in which we had no choice

When I last stopped count-

47, the Navy took charge

but to be 'general special-

of our appointments for

ists,' with a major in

After my Internship

4D

grandfather, Tom
Beahan, an Adirondack
Larry Beahan, MD '55, has
logger in the early 1900s.
published a book, titled, "Larry describes life in a
My Grampa's Woods,
lumber camp in the
the Adirondacks. Beahan, Adirondack woods of
a physician active in
1900 in an honest and
conservation efforts,
intimate way," writes a
has assembled a collecreviewer for Amazon.
tion of colorful stories
com, "so that you hear
spanning the 20th centhe noise of the loggers
tury. These tales of
talking at breakfast, taste
tragedy and death,
the hot cakes covered
humor and family lore
with maple syrup, and
stem from his family's
smell the horses as they
encounters in the
sweat and strain at
Adirondack Mountains
pulling the logs across
in northeast New York
the snow-covered
State, beginning with his forest floor."

1950s

luffal 1 Phys i c i an

Spring

2001

The theme plaque OYer

neration is "out of this

the door reads, 'For what

wortd." We wouldn't

ing, we had done OYer

does it profit a man to gain

switch jobs with any-

1,200 of them.

the whole world !including

body.

�assnotes

tion. I enjoy traveling
with my wife, Carol,
and our three wonderful
children." E-mail
is Dforster @pol.net.
Michael Nancollas, MD, '85,

senior at Columbia
University and Daniel is
a freshman at the
University of Pennsylvania, where he is
playing catcher for their
Division 1 baseball
team." E-mail is
hrgmd1@home.com.
Marguerite Dynski, MD '75,

Rochester, Y, general
surgery/breast disease,
writes: ''I'm a site
director of third-year
students from the
University of Rochester
and am on faculty at
RIT." E-mail address is
marguerite.dynski@
viahealth.org.
Claudette Robbins, MD '78,

writes: ''I'm no longer at
HDH, but am now a
full-time radiologist at
Olive View Medical
Center in Sylmar, CA.
E-mails are welcome:
claudettemd@yahoo.com."
Cavia L. Stanley, MD '78.

MDiv, is listed in the
2000 (millennium)
edition of Who 's Who in
Medicine and Healthcare.
He is the district health
director of Waccamaw
Public H ealth District in
South Carolina. The district includes Horry
Country (Myrtle Beach),

Georgetown and
Williamsburg counties.
Stanley is a gynecologist
in the U.S. Airforce
reserves and a
lieutenant colonel.

1980s
Ellen M. Tedaldi, MD ·so.

Philadelphia, PA, internal medicine, is director
of the HIV Program at
Temple Hospital. E-mail
address is etedaldi@
unix.temple.edu.

RPCI, where he is also
director of the institute's
Head and eck Surgical
Oncology Fellowship
Program. His research
interests focus on
respiratory epithelial
injury-repair and differentiation, and his laboratory is doing novel
work in bioengineering
large conducting
airway devices.

David Forster. MD '85, Oak

Hill, VA, ophthalmology, writes: ''I'm a clinical associate professor of
ophthalmology at
Georgetown University.
I'm also vice president of
the orthern Virginia
Academy of Ophthalmology and president of
Georgetown Ophthalmology Alumni Associa-

Fayetteville, NY, hand
surgery/orthopaedic
surgery, writes: "I started
a clinic for performing
artists, so I get to practice a different type of
'sports medicine,' treating musicians in the
Central ewYorkarea."
E-mail address is
hand.doctor@pobox.com.
CO N T I NUED ON P AGE 4 2

Wigand's "Secrets through the Smoke"

Wesley L. Hicks Jr. DDS,
MD '84, associate profes-

sor of otolaryngology/
head and neck surgery at
the University at Buffalo
School of
Medicine
md Biomedical
Sciences,
and attending
surgeon
in the Division of Head
and Neck Surgery at
Roswell Park Cancer
Institute (RPCI ), has
been invited by the
American Board of Otolaryngology to serve as
alternative guest exam iner for its 2001 oral examination and guest
examiner for its 2002
oral examination. In
1991, Hicks joined

Spri 11 g

200 1

laffala Physician

41

�CLASSNOTES

CONTINUED FROM PAGE 41

Roseann Russo, MD '85,

Manhasset, Y, pulmonary, critical care
medicine, writes: ''I'm
medical director of the
respiratory care unit at
orth Shore University
Hospital in Manhasset.
Am also the medical
director of pulmonary
rehabilitation for
NSUH/LIJ."
Lynda Stidham, MD '85,

Glenwood, NY, pediatrics, writes, "Two years
ago I returned to Christ
the King Seminary
where I am studying
pastoral ministry, which
is enriching my personal
and professional life immensely. I'm practicing
in a suburban pediatric
group."

199 s
Gale R. Burstein, MD '9D,

Decatur, GA, pediatrics
and adolescent medicine, is working as medical epidemiologist at the
Centers for Disease
Control and Prevention.
E-mail address is
gib5@cdc.gov.
Pamela A. Clark, MD '90,

Prospect, KY, pediatric
endocrinology, writes: "I
am currently chief of the
Division of Endocrinology at the University of
Louisville." E-mail address is paclark@pol.net.

42

l ulfal1 Pb ysiciaa

Mark A. Flanzenbaum, MD

Douglas P. Prevost, MD '90,

'90, Glen Allen, VA,

San Antonio, TX, orthopaedic surgery, writes: "I
am an army staff orthopaedic surgeon, chief of
joint service." E-mail
address is dprevost@
gateway. net.

emergency medicine and
pediatric emergency
medicine, writes: "I am a
faculty member at the
Medical College of Virginia." E-mail address is
mflanz@worldnet.att.net.

Eileen Schwartz Saltarelli,
Robert J. Leon, MD '90,

MD '90, Canton, OH, psy-

ew York, NY, writes:
"I live on the upper east
side of Manhattan. My
practice is located in NJ.
I enjoy the culture of
NYC and solo cardiology
practice." E-mail address
is rleonmd944@aol.com.

chiatry, writes: "I work
for a community mental
health agency and consult in 12 nursing
homes." E-mail address
is msaltdoc@aol.com.

Laura Nicholson, MD '90,

Palo Alto, CA medicine,
writes: "I joined Stanford University in 1997
as director of the Medical Consultation Service.
I also serve as medical
director of Inpatient
General Medicine and
associate program director of Internal Medicine
Residency. On weekends, I enjoy the great
outdoors of northern CA
and great indoors of San
Francisco." E-mail address is lnicho@leland.
stanford.edu.

Timur Sarac, MD '90,

Orange Village, OH,
vascular surgery, writes:
"I have spent nine years
in postgraduate education. Finally it's paying
off, as I am working with
my residency mentor at
the Cleveland Clinic."
E-mail address is
saract@ccf.org.
Valerie Vullo, MD '90,

Clarence, NY, physical
medicine and rehabilitation. "I am part of the
Department of Rehabilitation Medicine at UB
and a clinical assistant
professor at UB's School
of Medicine."

Spring

200 1

surgery at the University of California at
Davis in Sacramento,
CA." E-mail address is
rudolph.schrot@
ucdmc. ucdavis.ed u.

Cynthia Leberman Jenson,
MD '92, writes: ''I'm in

Kenneth A. Levey, MD '97,

private practice in
Bangor, ME, (anesthesiology). My husband,
Mark, is a stay-at-home
dad with our two daughters, Alexandra, age six,
and Erica, three." E-mail
address is mcaejenson@
adelphia. net.

writes: "I am completing
both my residency in
OB/GYN and my
master's degree in public
health this spring at the
George Washington
University. I will be
starting this summer as
assistant professor of
OB/GYN at the New

E-mai
Jon Kemp, MD '93, writes:

"Meri and I are in Portland, Oregon, and very
happy. We have two
little girls, Laurel and
Sophie. I am practicing
ophthalmology and not
taking too much call."
E-mail address is
jkemp899@aol.com.
Tara (Sosa) Paolini, MD '95,

Lisa M. Nocera, MD '90,

Greenville, NC, anesthesiology-pain management. I recently married,
moved and started a new
job! I'm as happy as I've
ever been!" E-mail
address is lmnocera@
hotmail.com.

cal care at UPMC
Passavant in Pittsburgh,
PA. I look forward to
retiring in 2035."

York University School
of Medicine."
Mark L. Capener, MD '99,

writes: "My practice is
going very well here in
Elko, NV. I also work in
Ely, NV, and in Winnamucca on alternative
weeks. Who woulda
thought? Hello to all the
gang in Buffalo!" E-mail
is: capeners@elko.net.

Steven P. Harris, MD '91,

and Raymond V. Paolini,

writes: "We are pleased
to announce the birth of
our third child, Elaina
Anne-Marie. She is welcomed by brothers
Donovan, age 4, and
Steven, age 5. I am currently in private practice
in pulmonary and criti-

MD '90, write: "We are

Thomas A. Cumbo, MD '99,

happy to announce the
birth of our daughter,
Dora Rae, on August 14,
2000." E-mail address is
tsosa@ yahoo.com.

writes: "I completed my
second research expedition to the epa! Himalayas last summer as a
PGY-2 resident at
The Johns Hopkins

Rudolph Schrot, MD '96,

writes: "I am currently
PGY-3 in neuro -

CONTINUED ON PAGE 44

�Erica (Heit) Remer pens amedical thriller

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Hospice really is a plan for living.
And the sooner you call, the sooner
we can help you put that plan into
action - with emotional support,
pain management, in-home care anything you need to keep
enjoying life . Call686-8077.

THE

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Spr i ng

200 1

luffalo Physiciaa

43

�C

L

A

CON TI NU ED FR O M P AC E 4 2

University/Sinai Hospital Program in Internal
Medicine. I led an eightman team from the Himalayan Rescue Association into the Langtang
region of the peaks (just
below Tibet) where we
gathered data to test a
hypothesis regarding the
pathogenesis of altitude
illness. We studied a
Hindu pilgrim population at a sacred high
altitude lake at approximately 4,500 meters. The
pilgrimage is an annual
event in honor of the
Vedic Diety Shiva and is
performed by approximately 4,000-5,000
individuals. In addition

In emo

N

0

T

E

tO COllecting data, We
were in charge of
providing medical care
for the masses in a
Third-World environment. It was an exciting
mix of basic science,
field research, ThirdWorld culture, backcountry medical care
and religion. I plan a
biannual trek to further
refine our numbers and
test novel hypotheses.
P.S. I have a letter to the
editor published about
high altitude medicine in
the January 2001 issue
of Emergency Medicine
on page 6. "

each donor specifies. The UB Foundation acts as the school's banker and
investment manager, charges minimal fees (much less than profitmaking financial institutions) and makes disbursements in accordance
with donors' stipulations. It is the Dean, however, who leads the development program. He articulates the vision and the dreams of the school.
Our office does assist with details , but it is the donors and volunteer
leaders who respond that make the dreams come true.
With appreciation to all of those who make philanthropy a high
priority, and on behalf of the ultimate beneficiaries , I thank our increasing number of committed james Platt White Society members. You make
such a crucial difference to our school.
CD

mda f. (h 11 Cordu may he reached, toll-j•H at 1-877-826-3246 or
mad at ljCOJ derCrobuffalo.edu.

CD

West Virginia; and Ronald of

Buffalo in 1945. A diplo-

in White Sulphur Springs,

Burbank, California.

mate of the National

board of trustees for

Board of Medical Examin-

Aiken County Rescue

West Virginia. Morhous was

Squad and chair of the

Board of Internal Medicine,

George Alex Poda,
MD '45, died on December

ers and the American

Eugene J. Morhous,
MD '45, died Septem-

Board of Preventive Medi-

South Carolina Regional

was a fellow of the Ameri-

22, 2000, at Aiken Re-

cine, he was the author of

Blood Bank. Poda orga-

gional Medical Center in

numerous papers and

nized the Sabin Polio

certified by the American

44

tal, was a member of the

staff at the Greenbrier Hotel

ber 11, 2000, at his

can College of Physicians

home in White Sulphur

and served as a member of

South Carolina. He was 79.

books on nuclear medi-

vaccine program in Aiken

Springs, West Virginia.

the National Board of Medi-

A native of Jamestown, NY,

cine. He served as an

County and Richmond

A native of Palmyra,

cal Examiners. He was a

Poda served as a captain

associate professor in the

County, GA, and champi-

New York, Morhous

past president of the Green-

in the U.S. Army Medical

Department of Community

oned the formation of the

received his under-

brier Valley Medical Society

Corps, both on active

Medicine at the Medical

associate degree nursing

graduate degree from

and was a member of the

duty and reserve status,

College of Georgia and

program at USC Aiken.

St. Lawrence University.

West Virginia State Medical

from 1941 to 1952, and

was a visiting lecturer on

He is survived by his wife,

Following graduation

Society and the American

later in the U.S. Navy

occupational medicine at

Anna Michele Poda; son,

from the University of

Medical Association.

Medical Corps.

the Medical University of

Steven Michael Poda,

Poda was a graduate of

Buffalo School of Medi-

Morhous, who was pre-

South Carolina (USC). He

Aiken, South Carolina;

cine in 1945, he prac·

ceded in death by his wife,

Alfred University and Mount

served as chair of the

and daughter, Deborah

ticed medicine for 35

Betty Jane, is survived by

Union College and com·

board of trustees of Aiken

Ann Poda Lyles, Spar·

years as a member of

two sons: Lawrence, and his

pleted his medical degree at

Country Hospital and later

tanburg, South Carolina.

the Greenbrier Clinic

wife, Carolyn, of Bluefield,

the University of

Aiken Community Hospi·

I UII aID

Ph ySiC iII

Spri11g

2001

CD

b~

�- Based on F/MsM Data

ffTheywere drJl sergeantsand cheerleaders~'
- Frank Ste/arski, stroke rehab

patien~

Harris Hill H.C.F

Why do our patients have better rehab results compared to the national average? Maybe it's our staff
''They knew exactly how far to push me,'' says Frank Stelarski. ''But they also encouraged me every little
step of the way. When you've been through what I have, that really means a

THE

lot:' To leam more about the nationally recognized McGuire Rehabilitation

~~cy}Jf1fl(91'{
CENTE~

Centers, call 1-888-POSTACUTE or visrt www.mcguire-group.com.

Recognized for excellence in quabty care.
AUTUMN VIEW

•

GARDEN

GATE

•

HARRIS

H*****"

HILL •

Spring

2001

NORTH

GATE

Bu f falo Pbysicin

45

�The State University of New York

A

R

A

UB's HISTORY
OF MEDICINE
COLLECTION PRESENTS

reproduced
prints from a pharmacopoeia by Otto Karl
Berg (r8rs-r866) were
on display last fall in
University at Buffalo's
Health Sciences Library
(HSL), South Campus.
The botanical show
was developed by the
HSL and the university's
iMedia staff and is the
first

in

a

series

of

"Art in the Library"
exhibits intended to
promote the His tory of
Medicine

Collection

through the display and
sale of reproductions of
selected works.
Fred Kwiecien and
Don Trainor of iMedia
prepared

the

prints

from the original art in
the Berg volume, published in Leipzig in

I863. Pictured is
Papaver somniferum.

BP 0004 01

�</text>
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LIB_R_AR_Y_ _

L - -_ _

j

ASSOCIATE VICE PRESIDENT FOR
UN I VERSITY COMMUN I CAT I ONS

Dr. C arole S nrit/1 Petro
D I RECTOR OF P ER I OD I CALS

Sue Wu e tcher

New Dean Named

EDITOR

S t ephani e A . U n ge r
ART DIRECTOR/DESIGNER

A lan f . Kegle r
N JUNE 28,2001,

University at Buffalo Provost Elizabeth D. Capaldi, PhD, announced that
CONTR I BUTING W R ITER

the positions of vice president for health affairs and dean of medicine would be recombined,

Lois Bake r

and she named Michael Bernardino, MD, MBA, to the role, effective immediately.
Bernardino has been serving as vice president for health affairs at UB since the spring of

PRODUCT I ON COORD I NATOR

Cy nthia Todd-Flick

1998. As the new dean of the School ofMedicine and Biomedical Sciences, he succeeds John
R. Wright, MD, who has served in that capacity since 1998 and as interim dean since 1997.

UN I VERS I TY AT B UFFALO
ScHOOL OF MED I CINE AND

Before assuming that role, Wright was chair ofUB's Department of Pathology for 23 years.
In citing reasons for the consolidation, Capaldi explained that "given the current
period of rapid change in the field of medicine, the university has decided that leadership for the school can most effectively be provided by one individual who is responsible
for its overall educational and research mission, its financial affairs and its relationship
with its affiliated teaching hospitals."
Capaldi also announced that Wright will continue to serve as professor of pathology in
the School of Medicine and Biomedical Sciences.
"We all appreciate Dr. Wright's leadership in developing the school's new curriculum
and in building a support base for the school with the alumni, students and other
constituencies," she said. "These contributions form a strong basis for continued excellence."
Prior to coming to UB, Bernardino served as director ()f managed care with the Emory
University System of Health Care, in Atlanta, and was a professor of radiology in the Emory
University School of Medicine. As vice president for health affairs at UB, he has been
responsible for overseeing the clinical and collaborative activities of the university's five
health sciences schools: medicine and biomedical sciences, dental medicine, health related
professions, nursing and pharmacy and pharmaceutical sciences. He has also been responsible for spearheading the university's relations with its affiliated teaching hospitals and
for leading the healthcscience deans in planning and executing joint and cooperative

B I OMED I CAL SCIENCES

Dr. Mi chael Bernardino, Dcatl
EDITOR I AL BOARD

Dr. john Bodkin
Dr. Martin Brech e r
Dr. Harold Brody
Dr. Linda f . C orde r
Jason Hoffman, C la ss of 2004
Dr. fame s Kan ski
Dr. Elizabeth Olm st ed
Dr. fames R . Olson
Dr. Stephen Spaulding
Dr. Bradley T. Truax
Dr. Franklin Zeplowitz
TEACH I NG H OSPITALS

Erie Co unty M edi cal Ce11t er
Ros well Park Ca11 ce r In stitut e
Ve tera11 s Affairs W es tenr
New York Health ca re Sys t em
K ALEIDA H EAITII:

T he Buffalo Ge11 eral Ho spital
Th e CIIildre11 's Ho sp i tal of Buffa lo
Mill ard Fillmo re Ga tes Hosp i tal
Mi llard Fillm ore S ubu rban H ospit al
CA TIIOLI(. H EALTH

s )'S1"EM :

M ercy Health Sys t em
Sis ters of Clwrity Hospit al

programs of teaching and research.
Earlier this spring, it was announced that Bruce Holm, PhD, senior associate dean for
research in the School of Medicine and Biomedical Sciences, has been given the additional

N iagara Fa lls M emoria l
M edi cal Ce 11t er

title of senior associate vice president for health affairs, reporting to Bernardino.

@

John Hay, PhD, Grant T. Fisher Chair of Microbiology at UB, has assumed Holm's
former administrative responsibilities related to the school's graduate programs in biomedical education. Also, the position of assistant dean for alumni affairs-formerly filled
by Bertram Partin, MD '53-has been discontinued, with plans under way to restructure
administrative roles in the Medical Alumni Office.

UNIYEISIIY l!IUIIILO.
THE STilE UNIYEISITY 01 NEW YORK

Letters to the Editor
Bllffalo Pl1ysician is published quarterly
by the University at Buffalo School of
Medicine and Biomedical Sciences in
cooperation with the Office of
Communications.

Ongoing developments at the School of Medicine and Biomedical Sciences will be
addressed in messages by Dr. Bernardino in upcoming issues of Buffalo Physician, as well as
in feature articles and news updates.
-

S .

A.

UNGER

Letters to the Editor are welcome
and can be sent c/o Buffalo Physiciall,
330 Crofts Hall, University at Buffalo,
Buffa lo, NY 14260; or via e-mail to
bp-notes@buffalo.cdu.
The staff reserves the right to ed it a ll
submissions for length and clarity.

T...:.:... University at B-~~';, 1York
~

The State University OJ

�VOLUME

36,

NUMBER 0

p

H

y

s

c

A

N

Features

2

'A Little Fire in the Belly'
Donald Finkel, MD '51,
.
.
p10neenng cancer
researcher and founder
of the Women, Infants
and Children Program
BY

10

S. A.

UNGER

Good Ways to Deliver Bad News
New course teaches students
how to deliver bad news in a
caring, effective way
BY

M.D.

This year'scommencement-held on May 18, 2001-marked the 155th at the University at Buffalo
School of Medicine and Biomedical Sciences. Pictured above is new graduate Timothy 8. Curry, MO/PhO.

KINNAMON

Cov

15 Departments
Merge

16 Match Day
20 CAT and
NYSTAR
programs
announced

23 Buffalo-Niagara
Medical
Campus group
formed

24 Graduation

26 Margaret
Paroski new
director
of admissions

27 Beutner and
Jordon receive
Discovery
Award

29 Robert Galpin,
MD, heads
pediatric orthopaedic surgery

30 Role of statins
in heart disease
topic of 200 l
Stockton
Kimball lecture
by Antonio
Gotto, dean of
Weill Medical
College, Cornell

31 Medical Alumni
Achievement
Awards

IMAGE BY PAM f-RAN

34 Michael Baron
reflects on his
medical career
after 30 years

35 Class reunion
photographs

s

38 Gifts of art
beautify the
school, inspire
students
jim Dine prints
presented to
school by
AAMC now on
display (see
back cover)

40 News from
your UB
classmates and
other alumni

43 In MemoriamClassmates
remembered
and their
accomplishments honored

�by S. A. Unger

Donald Pinkel, MD '51. pioneering cancer researcher and founder ofWIC Program
bout the time his Career began tO hit itS peak in the late 1960s, Donald Pinkel, MD '51,
found himself at the center of two controversies, the resolution of which would help redefine standards for pediatric care
during the latter half of the 20th century.
The first of these controversies revolved around the fact that Pinkel insisted on the feasibility of curing childhood leukemia
with agents that were then available, a stance that went in direct opposition to prominent pediatricians and hematologists at
the time who felt any use of the word "cure" in this context would give false hope to parents whose children had leukemia.
By the early 1970s, however, Pinkel and his colleagues had succeeded in silencing these critics by developing the first
curative drug treatment for acute lymphocytic leukemia (ALL) in children.
The second controversy, which grew out of the first, involved Pinkel's attempt to address the fact that many of the pediatric
hematology/oncology patients he and his colleagues were treating also suffered from chronic malnutrition directly related to
their socioeconomic status. As a result of this observation, Pinkel led a politically unpopular
effort to develop and prove the efficacy of a public-health initiative that later came to be called
"Everybody was getting
the Special Supplemental Food Program for Women, Infants and Children.
upset with us because we
Known to health-care professionals today as WIC, this
were talking about curing
program has since been adopted at the federal level by the Food
leukemia and they said,
and utrition Service of the United States Department of
'You can't do that,' and
Agriculture (USDA), which in its own literature refers to it as
"one of the nation's most successful and cost-effective nutrition
some people got pretty
intervention programs."
defensive and angry about
How did this native Buffalonian and graduate of the thenthat in the early days," he
University of Buffalo School of Medicine find himself on the
says. "We were trying to
front line of these key battles in oncologic research and publichealth policy? Pinkel-who returned to UB last September to
be modest, but still alot of
be honored as the 2000 Distinguished Medical Alumnusjournal editors and
explains that, in retrospect, his career was stimulated in its course
referees didn't like that
not so much by clear direction as by disturbing voids in health
kind of talk."
care for children.
2

laffal1 Physiciaa

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2 001

��inkel traces his interest in pediatric hematology/oncologyback to 1949,
when, as a second-year medical student, he had the "good fortune" to take an elective in hematology with the renowned
clinician David K. Miller, MD, who was head of medicine at E.). Meyer Memorial Hospital (now Erie County Medical
Center). "I saw my first child leukemia patient while making rounds with Dr. Miller, and at that point I became very
interested in these children. So, by the time I graduated from medical school I was, as you might say, 'into' hematology,"
he explains.
This interest was reinforced during the first few months of Pinkel's internship at Children's Hospital of Buffalo
(CHOB). "One of my first patients was a newly admitted child with all the symptoms and signs of leukemia, which I was
pretty familiar with by then," he recalls, "so I made the diagnosis and was in the position of having to inform the parents
that their child was going to die, because this diagnosis was like a death warrant then.
"This was a very disturbing experience for a young person right out of medical school-so disturbing, in fact, that I
felt l couldn't run away from it, which might be one's first impulse," he adds.

Despite his strong interest in pediatric hematology/oncology,
Pinkel had few role models he could look to at that time because
the fields of hematology and oncology were still in their infancy,
too new to recognize or support individuals with subspecialty
interests. In fact, during the time he was a resident at CHOB, the
hospital employed only one part-time pediatric hematologist,
George Selkirk, MD, whom Pinkel remembers as being very
encouraging and supportive.
While serving as chief resident during his third year of training,
Pinkel received a welcome boost to his aspirations when Selkirk
took him aside and asked if he would like to take on a project to
develop a tumor clinic at the hospital. "Dr. Selkirk had received
funding from the American Cancer Society for a
tumor board at Children's, so with those fundsand with the approval of Dr. Mitchell Rubin,
chairman of pediatrics-he set me up with an office
and a part-time secretary, and I began to review
all the patients at Children's who had ever been
diagnosed with cancer," he explains.
Gradually, because there was no full-time
hematologist/oncologist on staff at the hospital,
Pinkel began to be called in to see all the children
diagnosed with leukemia and other forms of cancer. "You have to understand, no one was doing
much then with children who had cancer. Attitudes
were negative everywhere," he emphasizes. "It was
a very sad situation, so somebody had to get in there
and start it."
Over the course of his residency, therefore,
Pinkel became that "somebody" who stepped in
to fill the void.
"By the time I finished my residency, I had
become the [hospital's] unofficial pediatric oncologist because of my special interest in children
with cancer," he says. "I also sensed that much
more could be done, at least in terms of pain relief
and comfort for the children and their families."

lallala Phys iciaa

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"Real" Postgra~uate Training in Me~icine
Having had the opportunity to see that he could, in fact, "get in
there and start it," Pinkel was eager to seek greater exposure to his
newly chosen field. Prior to completing his residency in June 1954,
therefore, he applied for a fellowship at Memorial Sloan-Kettering
Cancer Center in New York City and was accepted. Soon thereafter, however, his plans changed dramatically when he received
notification that he had been activated out of his reserve unit at
UB, the 338th General Hospital, which he had joined as a commissioned officer following graduation from medical school. In
a twist of fate that would change his life in ways he never could
have foreseen, Pinkel was
assigned as head of pediatrics at the station hospital
at Fort Devens, Massachusetts. There, not long after
his arrival, he contracted
poliomyelitis and became
severely disabled, requiring
hospitalization for six
months at nearby Murphy
Army Hospital in Waltham,
Massachusetts.
"I was extremely ill with it
for a while, but after about
six weeks I could start raising my head, and after
about three or four months,
I was able to ambulate some
with long leg braces and
crutches," Pinkel recalls.
Upon discharge from Murphy Army Hospital, the 28year-old Pinkel was retired
from the army on full, permanent disability. Still on
long leg braces and crutches,

�''Th.IS was the first curative treatment of any kind
for leukemia and the first time that cancer had been cured
primarily with drugs;' he notes. "It was also the first time
that people who had generalized cancer were cured, so it
was important in three different ways:'
-------

he was transferred to a Veteran's Administration hospital outside
Boston, where his rehabilitation continued for another year. Referring to this time as his "real postgraduate training in medicine," Pinkel recounts how after a year at the VA, most of
which was spent in half-day outpatient physical therapy sessions,
he progressed to where he was free of the wheelchair and could
rely solely on short leg braces and a cane to walk. "So, after a
while, I was able to move along and was very fortunate," he says.
As part of his rehabilitation, Pinkel was encouraged to resume
working, so the very first day he received his driver's license after
relearning how to drive, he headed to Boston Children's Hospital
preceded by a letter of introduction from Dr. Rubin at CHOB.
The letter was addressed to Dr. Charles Janeway, who referred
him to Dr. Sydney Farber, a fellow native Buffalonian and
oncologist whose contributions to his field eventually led to
Harvard University naming its Dana Farber Cancer Institute in
his honor. "When I saw Dr. Farber, he hired me on the spot as a
half-time fellow, and I began to work in the Jimmy Fund Clinic
at Boston Children's Hospital. In this way I resumed my interest
and my activity in hematology and cancer, especially leukemia,"
explains Pinkel.

Back to Buffalo, and Beyond
Toward the end of his first year as a fellow
with Farber, Pinkel was contacted by Rubin
and George Moore, MD, the new director at
Roswell Park Cancer Institute (RPCI), who
asked him if he would consider returning to
Buffalo to establish a pediatric service at
RPCI, as well as join the faculty at UB and the
staff at CHOB.
The answer was yes, and by April 1956,
following discharge from the VA hospital,
he was on his way back to Buffalo. In the five
and a half years of whirlwind activity that
followed, Pinkel set about organizing the
new pediatric inpatient unit, clinic, laboratory and research programs at Roswell Park,

while concurrently conducting his own
research, teaching and seeing patients.
Then, in 1961, Pinkel was asked to
become the first director of St. Jude
Children's Research Hospital, which
was under construction in Memphis,
Tennessee. As envisioned by its founder, entertainer Danny Thomas, the hospital would become the first institution
in the United States devoted solely to
basic and clinical pediatric research and
the first racially integrated institution
in that region.
Pinkel accepted the offer and began
preparing for his move to Memphis in
October 1961. As it turned out, however, he didn't leave Buffalo without
what would later prove to be a providential encounter in the airport with a
former UB medical school professor,
John Talbott, MD, who was also on his way out of town, having
resigned as head of medicine at Buffalo General Hospital to
accept the editorship of the Journal
of the American
Medical Association
(lAMA). While in
the airport, the two
physicians had an
opportunity to talk
about their work
and Talbott, sensing a future in the
drug-intervention
studies Pinkel was
describing for pediatric malignancies,
encouraged him to
submit papers on

S ummer

200/

l ulfale Physician

5

�his work to ]AMA. In the years ahead, both men recognized this
meeting as a catalyst to Talbott's support of Pinkel's innovative studies at a time when other leaders in the medical community were skeptical.

ne Controversial Cure
Before Pinkel could begin building a world-class research program
at St. Jude Hospital, he first had to attend to a few practical details
upon his arrival at the hospital, which was still a work in progress.
"I was the first person in the building," he recalls with a laugh. "I
had a card table and a chair, and we
strung a wire out to the telephone pole
and another wire out to the electrical
pole for my plugged-in heater, and I
was in business!"
Indeed Pinkel was in business, and
over the course of the next few years,
he oversaw the hiring of staff, the organization of basic and clinical research
programs and the building of inpatient
and outpatient clinics, while at the same
time he worked to raise money needed
to complete construction of the hospital in March 1962.
"Shortly after we opened, it occurred
to me that we actually ought to be trying to cure ALL, rather than just palliate
it," Pinkel recalls. "But no one was talking about trying to cure it at that point
because all attempts had been unsuccessful. Scientifically, the pessimism
was justifiable because we did not
know its cause or mechanism. However, a key feature of St. Jude was the
integration of basic and clinical research. And the basic scientists
at the hospital were adamant that there was an excellent theoretical basis for curative treatment of ALL with drug combinations."
In contrast to the mute resignation that was prevalent at that
time, Pinkel and his group moved into action, devising a new plan
they called "total therapy," which remains the standard for treatment today. "The idea was that we would use drug combinations:
one set for induction of remission, another set for intensive
chemotherapy, and another set for continuation," he explains.
"Then we used specific therapy aimed at the CNS [central nervous
system] based on the observation that children on therapy with
normal-appearing bone marrow were coming down with first
relapse in the CNS because our drugs weren't getting into the
cerebrospinal fluid."
For the next five years, the St. Jude researchers conducted pilot
studies that, while promising, were very difficult. "We encountered lots of new problems that we had not seen before because
of the immunosuppression we were inducing in the children,"

6

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Pinkel explains. By the time a fifth pilot study had been completed in 1968, however, Pinkel and his colleagues could see that they
had something. "As it turned out later, we had reached a point
where we were able to cure half the children . This was the first
curative treatment of any kind for leukemia and the first time
that cancer had been cured primarily with drugs," he notes. "It
was also the first time that people who had generalized cancer
were cured, so it was important in three different ways."
Despite these milestones, Pinkel at first could not win support
for the studies from some of his peers and was even "thrown out
of' two leading oncology groups whose leadership disagreed with
the protocols he was developing and felt strongly that the St. Jude
team should not be focusing on trying to cure ALL. "Everybody
was getting upset with us because we were talking about curing
leukemia and they said, 'You can't do that,' and some people got
pretty defensive and angry about that in the early days,'' he says.
"We were trying to be modest, but still a lot of journal editors
and referees didn't like that kind of talk."
Talbott, who had followed Pinkel's work closely over the
intervening years since their meeting in the Buffalo Airport, did
like that kind of talk, and in 1971 he helped change the field of
oncology forever by lending his support to publishing a paper in
lAMA on Pinkel's five-year follow-up study. In fact, so confident
was Talbott in the merit of the paper, he selected a special cover to
highlight it and wrote an accompanying editorial to extol the
work being done at St. Jude Children's Research Hospital.
In recounting this historic show of support by Talbott, Pinkel
says, "That was the first time the phrase 'five-year cure rate' was
applied to leukemia in a medical journal. I'm not sure any other
journal would have allowed that statement then."
A year later, Pinkel won the Albert Lasker Award for Medical
Research . Often called "America's Nobel's,'' Lasker Awards are
our nation's most distinguished honor for outstanding contributions to basic and clinical medical research.

rood as aPrescri~tion
While Pinkel and his group could not help but savor seeing children cured of ALL, a problem that had come to light as they were
conducting their studies
on cancer had thrown a
long shadow over their
accomplishments.
"We found that we
were seeing children in
that area [Memphis]
with leukemia and other
forms of cancer who in
fact had two diseases: not
only cancer, but malnutrition, as well," Pinkel
says. "This made it very
difficult to treat their

�"Actually,

we got into a lot of trouble for this

[program];' he continues. "You have to remember this
was the time of the civil rights movement and most of the
youngsters we were seeing were from very poor black
families, so people thought WIC was another form of
civil rights agitation."
cancers because they had such a low tolerance for the chemotherapy due to their poor nutrition."
Realizing that the problem of malnutrition was rampant, especially among low-income African-American children in South
Memphis, Pinkel began to recognize the need to address this
threat to children's health at a community-wide level, not just in
terms of how it was impacting those with cancer.
In a move that put him well ahead of his time, Pinkel had recruited a full-time MD/PhD nutritionist, Paul Zee, when St. Jude
first opened. Together they identified people in the community
willing to work with them to establish clinics and a "nutrition
warehouse" where food was collected for strategic dissemination
to needy women and children. "In this way, we were able to tie in
well-child care and prenatal care with the active-feeding program," says Pinkel. "The idea was food as treatment-food as a
prescription-and that really hit home and was highly effective.
"The food program the St. Jude team carried out was different
from other food programs," he adds, "because we conducted a
scientific study to test the effectiveness of combining food prescriptions with prenatal and preventive infant and child care. The
results of the study documented not only the health-effectiveness,
but also the cost-effectiveness of this combined approach to maternal and child health at a community level."
As word about the success of the program spread, a local television station became interested and produced a documentary about
it that ignited a political firestorm when it first aired. "Many people
in Memphis didn't like it at all," Pinkel explains, referring to his
nutrition program. So unpopular was it that the city's mayor felt
compelled to call Pinkel and assert that he was giving the city a
bad image.
"When he told me this, I said, 'Wait, maybe you should look at
it differently; maybe you should look at it as giving the city a good
image because you are recognizing the problem and doing something about it, which is better than what other cities are doing,"'
Pinkel explains. "But that didn't go over very well.
"Actually, we got into a lot of trouble for this [program]," he
continues. "You have to remember this was the time of the civil

rights movement and most of the youngsters we were seeing were
from very poor black families, so people thought WIC was another
form of civil rights agitation. As a matter of fact, some of our St.
Jude donors said they wouldn't contribute to the hospital anymore, which got our fund -raisers pretty upset with me."
In the meantime, the television station that produced the
controversial documentary had been unable to find a sponsor. As
a result, they sold it to a national network called DuMont Televi-

SLi mm er

200 1

Buffalo Pbysiciaa

7

�"The Ion er that I've been out of school and
have taught at other medical schools, the more I appreciate the fact that the medical education we received at
UB was really superb:'
sion, which ran it as a late-night filler-"You know, one of those
shows for insomniacs," says Pinkel.
As the story goes, one such insomniac who just happened to
tune into the documentary was Senator Hubert Humphrey from
Minnesota. Galvanized by what he saw, Humphrey immediately
became interested in the St. Jude Nutrition and Health Program and held
hearings on Capitol Hill to investigate
the problem of malnutrition in the
country. "One of our people went to
Washington and testified at the hearings," recalls Pinkel. "Senator Humphrey became very involved in this
project and was responsible for getting
Women, Infants and Children (WIC)
legislation passed in the Congress. Before he died, he said he considered this
to be his greatest achievement, and the
Senate voted unanimous approval of
increased funding in his honor."
Pinkel, too, considers the WIC program St. Jude' s most noteworthy
achievement, surpassing even the
curative drug therapy for ALL. "Leukemia is a relatively rare disease, but
malnutrition is the most prevalent,
fatal and disabling childhood illness
worldwide," he says.
However, because ofthe tenor of the
times and the study's revelation of
widespread malnutrition in a high proportion of AfricanAmerican children in a wealthy American city, the St. Jude team
was concerned that no journal would accept the study for
publication, according to Pinkel.
"I suggested to the senior author, Dr. Zee, that it be sent to
lAMA because of Dr. Talbott's enlightened attitude and the fact
that a student on our team had received an AMA Goldberger
scholarship in nutrition," explains Pinkel. "Although peer review
was favorable, I am convinced that, again, Dr. Talbott influenced its publication and the subsequent wide dissemination of
our results.
"It was this publication, plus a follow-up study in the AMA
Journal of Diseases of Children, that documented remarkable im8

l uffal1 Pbysiciaa

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200 1

provement in nutrition and health from our program, convincing
even the most conservative [individuals) to support WIC."

Building on aProven Track Record
In 1974, Pinkelleft St. Jude Hospital and embarked on a stage in
his career that involved being recruited to fill a series ofleadership
positions at institutions eager to capitalize on his proven track
record as a researcher, administrator and teacher. The first stop
was in Wisconsin, where he was professor and chair of the Department of Pediatrics at The Medical College of Wisconsin
and pediatrician-in-chief at the Milwaukee Children's Hospital,
and where he established the Midwest Children's Cancer Center.
Fours years later, he accepted a position as chair of the Department of Pediatrics at City of Hope ational Medical Center in
Duarte, California, just outside Los Angeles. There, he established pediatric inpatient and outpatient units and research laboratories in the Familian Children's Hospital.
In 1982, he again pulled up stakes and moved to Philadelphia,
where he assumed the chair of pediatrics at Temple University
Medical School and the medical directorship of St. Christopher's
Hospital for Children.
"!was in Philadelphia long enough to get accomplished what I
had wanted to do there, which was to make certain that a new
hospital was built in the inner city rather than in a distant suburb,"
says Pinkel. "Then, I decided it was time to return to my research,
so in 1985 I took a position at the University of Texas M. D.
Anderson Cancer Center in Houston in an endowed chair in
pediatric leukemia research, from which I retired in 1993."
Currently, Pinkel continues to work part-time, at Driscoll
Children's Hospital in Corpus Christi as a professor of pediatrics
at Texas A&amp;M College of Medicine. He also teaches, consults and
chairs the Institutional Review Board [at the hospital) and is
especially concerned about biomedical ethics.

Challenges for the future
After devoting more than 50 years of his life to helping define the
frontiers of pediatric oncology, Pinkel is crystal clear when asked
what he feels the major challenges are for the field today. "First," he
says, "we need to find out what causes these cancers and eliminate
these causes, because that's the only way to handle any pediatric
disease, just as was the case with polio, diphtheria, rickets, scurvyall those terrible diseases."

�them. They were also very aware of the 'art' of medicine-of
looking at the whole patient, looking straight in the patient's
eyes and listening. That's something many of the students today
aren't learning."
Pausing, he adds: "And I do think medicine is an art, and in
order to be successful, it not only takes scientific discipline and
integrity and devotion, but it also takes imagination, intuition and
passion. You have to have a little fire in your belly."
CD

He also contends that researchers need to find
much simpler ways of treating pediatric malignancies because the therapies being used today are too
complex and expensive. "By that I mean, there can be
a treatment that's 100 percent effective, but if only 20
percent of the children in need have access to it, then
it's only 20 percent effective.
"The treatment needs to be simple enough for a
'barefoot doctor' with an eighth-grade education to
use," he continues. "One of the big problems we've
had in the last 20 years is that we've been moving
toward more and more sophisticated treatments
that are complex and expensive-like megatherapy
and stem cell transplantation. These have been a
disaster as far as I'm concerned because they've
moved us away from making therapy available to
everyone and have separated even more the 'haves'
and 'have-nots' in this world."
The most promising future for pediatric
oncology, Pinkel asserts, is in molecular genetics,
"where we can develop therapies that work to
block the expression of disease-causing genes or
gene products. This is where we need to be putting
our energies."

Mr. Danny Thomas
Paramount TV
5451 Marathon Street
Hollywood, CaiHornia 90028

Carrying on the UBlradition
When working with students throughout his career-whether in the laboratory, the clinic or the
classroom-Pinkel says he has tried to carry on the
tradition of teaching from which he benefited while
a student at UB's School of Medicine.
"I feel sorry for all the medical students I teach
who can't go to UB," he says. "The longer that I've
been out of school and have taught at other medical schools, the more I appreciate the fact that the
medical education we received at UB was really
superb. We had very good clinical faculty who
were inspiring; they made you want to be a doctor,
and they made you want to be good doctors like

* Talbott was professor of medicine at the then-University of
Buffalo and chief of medicine at Buffalo General Hospital
from 1946 to 1959. In 1959 he left UB to assume the
editorship of the Journal of the American Medical Association, a position he held unti/1971. Entertainer Danny
Thomas founded St. Jude Research Hospital in 1962.

5

II Ill Ill C

r 200 I

luffala Pbysician

9

�ILLUSTRATION

BY

RANDY

LYHUS

�BY

M.D.

KINNAMON

New course helps students learn essential communication skill

...........

..Haw to Bnak Bad

module within the

school's two·
year-lang Clinical

Practice of
Medicine caursa

Summer

2001

�''

ow

TO

BREAK BAD NEws," a new module within the school's two-year-long

Clinical Practice of Medicine course, evolved in part from informal teaching
interactions the medical school had with a local Chemotherapy Coach Program.
As director of the program, Hillary Ruchlin often gave presentations to UB medical students about how best to communicate with seriously ill patients. To enhance
the immediacy of her message, Ruchlin, who is now executive director of the Cancer
Wellness Center in Buffalo, always brought along volunteers-«chemo coaches"who were cancer survivors. Her idea to introduce doctors- in-training to the feelings
and experiences of cancer patients in a more structured environment evolved from
seeing students questioning volunteers after the sessions.
"I thought [the new module] would be a wonderful way to

of the Standardized Patient Program, who organizes and in-

help students understand just what is at stake the moment
patients are told they have cancer," says Ruchlin. "It is a life-

structs the patients in their real-to-life role-playing scenarios

altering moment."
Ruchlin approached Alan Baer, MD, UB associate professor of medicine, and they collaborated on the development of the curricular module, now referred to as the "Bad

and in how to give feedback to students on the Bad News
Checklist (see page 14); Diana R. Anderson, EdM, who assists
with the administration of the Standardized Patient Program; and Deborah Waldrop, PhD, assistant professor in
UB's School of Social Work.

News Project." Their aim was to teach students how to give
bad news to patients and to reinforce appropriate methods

[motionally Charged Communication Issues

by using a format that involves the participation of actual

Dennis Nadler, MD, associate dean for academic and cur-

cancer patients.

ricular affairs in the Office of Medical Education, thinks

To develop the curriculum, Baer looked to Dr. Robert

"How to Break Bad News" is an idea whose time has come.

Buckman's pioneering work on the subject as described in

"This is a critical aspect of medical education, one that has

his book How to Break Bad News: A Guide for Health Care

Professionals (Johns Hopkins University Press, 1992).

been left to on-the-job training for much too long," he says.
"Actual cancer survivors

Buckman, an oncologist at the Toronto-Bayview Regional

are uniquely positioned to

Cancer Centre (Ontario, Canada) and professor of medicine

help young physicians

at the University of Toronto, developed a method that

learn how to do it right."

with, and for me, the

stresses the need for physicians to assess the patient's level of

Baer thinks students

encounter felt abso-

understanding of the possible diagnosis. His methodology

need help with these emo-

lutely real because I

also emphasizes the importance of using unambiguous lan-

tionally charged communi-

could see in their faces

guage, presenting information honestly, identifying sources

cation issues. "Historical-

of emotional support and presenting a clear plan for therapy.

ly, physicians have been

In addition to Ruchlin, Baer worked to develop the mod-

blamed for not doing this
well," he explains. "Many

ule with UB medical school faculty and staff, including Jack
Freer, MD, associate professor of clinical medicine and social
and preventive medicine, who teaches the first session of the
class and oversees the school's palliative care elective; Karen
H. Zinnerstrom, PhD, coordinator for training and evaluation

12

"For the patients I dealt

I I f f a I I Pb y s i t i a I

Summer

2001

they had gone through
this before. One patient
told me that it's almost

patients have stories of
how they first learned

like reliving the whole

about diagnoses of cancer,
and often it's not very

tions were authentic."

experience. Her emo·

�flattering to the medical profession. So now there's a protocol,
a step-wise method for teaching students these skills."
First taught in January 2000, the four-week-long module
begins with two weeks of introductory material that includes
lessons on the protocol for how to break bad news; a presentation of Buckman's video, "How to Break Bad News"; and a
discussion with a panel of former cancer patients. The panelists describe their experiences, including how they were given
their diagnoses, how they handled the information, how they
would have preferred to have been told (if it was a bad
experience), what they felt upon learning the news, and how
they survived their illnesses.
In the third and fourth weeks, role-playing begins. During
these videotaped sessions, which take place in examination
rooms of the Standardized Patient Testing Suite, students
present the cancer diagnosis to "patients" using fictional case
histories they've learned ahead of time. The patients, who are
actual cancer survivors, are then able to give feedback on how
effectively their "doctors" communicated the news. Patients
complete a written evaluation checklist on the student's performance, and students are given pre- and post-tests to assess
their approach to the task before and after their classroom
and role-play experiences.

Authentic [motions, Authentic Results
In its first year the module was conducted as a research project, with Deborah Waldrop from the School of Social
Work helping to design the research methodology. In
October 2000, Baer presented an abstract on the project's
findings at the Association of American Medical Colleges'
annual meeting in Chicago. Titled "Breaking Bad News:
Use of Cancer Survivors in Role-Play Teaching," the
abstract described significant differences in students'
approaches to breaking bad news based on the pre- and

post-test results. After completing the module, Baer
reported students used impersonal and technically specific language less frequently and instead adopted more
personal, empathetic and reassuring phrasing.

W

hile many medical schools use standardized patients
(scripted actors) in teaching, the use of actual cancer
survivors is what makes UB's program unique. "It
feels more real when you're dealing with a person
who has been through it," notes Baer. "Students gain confidence and walk away feeling like what they've heard is valid
and meaningful."
To student Jennifer Payne, role-playing was the most
valuable part of the sessions. "It made the biggest impact on
all of us," she says. "For the patients I dealt with, and for me,
the encounter felt absolutely real because I could see in their
faces they had gone through this before. One patient told
me that it's almost like reliving the whole experience. Her
emotions were authentic."
In order for all 140 second-year students to participate
in the role-playing, each of the 12 volunteer "patients" had
to hear the bad news up to six times a day in a two-hour
period. Though these dedicated volunteers were eager to
work with the students, it was difficult for them to relive
the trauma they experienced upon learning they had cancer.
Cancer survivor Ann O'Neil-Merritt, who is fully recovered from a rare cancer she was diagnosed with six years
ago, says, "Participating [in the module] this year was a lot
easier than last year. I'm one more year removed from the
day I found out, but it's very difficult because you're trying
to react honestly by putting yourself in the situation you
were in and reacting like you did."
Ruchlin adds, "We had volunteers 17 years removed from
their [cancer diagnosis] who were still having a difficult time."

Ultimately, "How to Break Bad News" is about communication and human
connection. "The class helped all of us realize that you have to establish a
rapport with your patient," Payne reflects.

�e s" Chec list for Student reed back

On Their Team to Help Them through It
The experience was trying for the students as well, although in a
different way. Payne explains that her confidence going into the
role-playing was shaky, as was that of her peers. "All of us were
exceptionally nervous. It was the most difficult thing we've had
to do yet in terms of actual patient interaction," she says. "But
it made me realize that this is as much a skill as is listening
to a heart."
Former patient O'Neil-Merritt got involved with the project
"to awaken these soon-to-be doctors to the fact that we' re more
than bodies. We're a whole organism, not just a set of cells." She
also wanted to impart to the students the importance of paying
attention. "Listen, watch and pick up clues from your patient
and then react to them. Change your agenda and your protocol
to meet the patient's needs because every patient will react
differently. You have to be aware of what their emotions and
body language are telling you," she says.

1. The student introduced him/herself.
2. The student addressed me by my proper name (i.e., did not call me by
my first name).
3. The student began our conversation with a question as to my current
well-being, health or state of mind.
4. The student asked me what I understood so far; about the symptoms
I have been having; about my illness, or the reason for the diagnostic
tests that had been performed.
5. The student asked me if I knew the results of the diagnostic tests that
were performed.
6. The student asked me how much I would like to know about my illness.
7. The student checked with me several times during his/her explanation
to make sure that I understood what was being said.
8. The student told me that the biopsy results were those of "cancer"
(and not simply a "tumor" or "growth").
9. The student described the possible forms of treatment that I
might need.
10. The student identified sources of support for me (e.g., family, friends,
community, professional).
11. The student outlined a clear plan for the future.

A

ccording to Baer, the medical education community is becoming increasingly interested in ways to develop the skill of
communicating bad news, especially since many experienced doctors did not have this kind of training as students.

"We'd love to present this program to physicians as a reminder,"
says Ruchlin. Associate Dean Nadler agrees, "Every health-care
professional should be given this sensitivity training. This is

12. The student ended the interview with an appropriate, polite closure.

Standardized patients are asked whether they "agree strongly," "agree,"
"do not agree or disagree," "disagree," or "disagree strongly" with
the following:

training that house officers and many faculty could benefit

* The student appeared comfortable in his/her communication with me.
* The student maintained appropriate eye contact with me throughout

from, as well, not just medical students."
Ultimately, "How to Break Bad News" is about communication

* The student explained the results of the diagnostic test and/or my ill

and human connection. "The class helped all of us realize that you
have to establish a rapport with your patient," Payne reflects. "!
assumed that doctors provided the information to patients and
then let them go off and determine how they're going to deal with
it from then on. But Dr. Buckman's protocol emphasizes that a
physician should take a more active role and should be on their
team to help them through it."

CD

the interview.
ness in a language that I could easily understand.

* The student facilitated the expression of my concerns and fears (e.g.,
possibility of impotence, need for mastectomy, fear of pain and death).

* The student behaved warmly, but professionally, throughout our
encounter.

* The student acknowledged and responded em pathetically to my ex
pressed fears, crying, tears, or other signs of emotion.

* The student guided our dialogue along in a manner which made me
feel comfortable.

* Overall Rating: The student did an excellent job in presenting me with
bad news.

According to [Dr. Alan] Baer, the medical education community is becoming increas·
ingly interested in ways to develop the skill of communicating bad news, especially
since many experienced doctors did not have this kind of training as students.

�B v

S

A.

UNGER

Department of Pathology
and Anatomical Sciences
formed

N

FOLLOW-UP TO A PLAN that was first proposed

over four years ago, the Departments of Pathology

to give anatomy, which is a pure
basic science, a clinical base by linking it with pathology, which is both a

and of Anatomy and Cell Biology in the University at

clinical and a basic science," accord-

Buffalo School of Medicine and Biomedical Sciences

ing to Heffner.
Heffner explains that yet another

officially merged in March 2001 to form the Depart-

factor leading to the merger was that

ment of Pathology and Anatomical Sciences. The
department is chaired by Reid Heffner, MD, formerly

both departments had become smaller

chair of the Department of Pathology.

together a "critical mass" of talent to

At the time of the merger, the Department of Anatomy

in recent years, and the combining of
faculty was viewed as a means to bring

foster new research initiatives, especially in the neurosciences.

ations, according to Heffner, including the fact that

The proposal to merge the two departments was extensively reviewed by the Faculty Council, which established an ad hoc committee chaired by Distinguished
Teaching Professor of Physiology and Biophysics Perry

basic science departments, in general, are increasingly

Hogan, PhD, to study its merits. After meeting with

and Cell Biology, which had been without a chair since
1992, was being led by interim chair Frank Mendel, PhD.
The merger was prompted by a number of consider-

focused on overlapping areas of research, a trend that is
particularly accentuated in the anatomical sciences and

"THERE'S BEEN A MERGING OF BASIC SCIENCES IN A

pathology because both disciplines are historically
rooted in morphology.
"There's been a merging of basic sciences in a sense
that they all are now directly involved in such questions

SE SE THAT THEY ALL ARE NOW DIRECTLY INVOLVED I
SUCH QUESTIONS AS 'How DO GENES REGULATE CELLS?

as 'How do genes regulate cells? How do they manufac-

How DO THEY MANUFACTURE PROTEINS, AND HOW DO

ture proteins, and how do they regulate growth?'" says
Heffner. "Even though [anatomical sciences and pathol-

THEY REGULATE GROWTH?'" SAYS HEFFNER.

ogy] have morphology in common, we are also like a lot
of the other basic science departments in that we are

faculty from both departments, the committee wrote a

investigating disease and cell and tissue function using

report supporting the merger and making several recom -

the same techniques, whether it's physiology, pharma-

mendations, including that new bylaws and policies and

cology, anatomy or pathology. So there's a lot ofblurring
between departments; we're not as compartmentalized

procedures be written for the department and that addi tional faculty be recruited. Committee members also

as we used to be."
A related reason for the merger is the planned imple-

endorsed formation of a Division of Anatomy within the
department, a step that has been taken, according to

mentation in fall 200l of a new curriculum in the School

Heffner. After two-thirds of the members of the Faculty

of Medicine and Biomedical Sciences that will place an

Council voted to approve the merger in October 2000,

emphasis on the integration of all basic sciences and in

the process for consideration of the proposed merger

making those sciences clinically relevant to students.

was reviewed and approved by the Faculty Senate, con-

"One of the goals with this merger, therefore, was

cluding two years of faculty input on the decision. &lt;!:)

S umm er

200 1

lufl alo Pbysiciaa

15

�MEDICAL

SCHOOL

N

E

w

S

Stacey Blyth, left, will stay in Buffalo and train in
family practice, while friend Amy Woolever is headed
for Einstein/Montefiore to train in pediatrics.

;;

..
..•

L

lbdelrazeq, Sonya

z

SUNY/Buffalo Graduate MedicalDental Education Consortium
BUFFALO,
y

Obstetrics-GYJlecology

Adams, Christopher
Orthopaedic Surgery

HIS YEAR's NATIONAL RESIDENCY MATCHING PROGRAM (NRMP) results

Eve Sisser with her husband,
ToddSullivan,andtheirsnen·
week·old daughter Leeba,
celebrate Eve's placement in
psychiatryatLonglsland
Jewish Hospital.

were announced on March 22 by Dennis Nadler, MD, associate
dean in University at Buffalo's School of Medicine and Bio·
medical Sciences. Of UB's graduating medical students 80
percent of the students received their first, sec~nd or third
. .
choice of placements. Thirty percent will stay m Buffal~ to tram m the Graduate
Medicai·Dental Education Consortium, while 45 percent will go out of state.
"Competition for desirable residency positions continues to be intense," says
Nadler. "We are very pleased that our students consistently match to some of the
best programs in the country."
Nationally, match results this year reflected a shift away from trends of recent
years where new physicians showed greater interest in family practice programs
and less interest for certain specialties, according to the NRMP. This year, the
number of individuals entering family practice residency programs decreased
by 4.9 percent. Conversely, specialties such as anesthesiology and pathology
showed increases of 5.8 and 8.1 percent respectively.
Despite the decline in family practice, 51 percent of graduating U.S. medical
school seniors matched to a first·year residency position in one of the generalist
positions. Among the UB students, 26 were placed in internal medicine, 22 in pediat·
rics, 12 in family medicine, 4in medicine-pediatrics and 3in obstetrics-gynecology.
Overall, 23,981 individuals participated in the match this year, a decrease from
the 25,056 who participated in 2000. Of the total active applicants, 76.5 percent
were matched to afirst·year position, a3.1 increase over last year.
-S. A.

UNGER

Mayo Graduate School of Medicine
ROCHESTER, MN

Adamson, Jennifer
Family Practice
SUNY/Buffalo Graduate MedicalDental Education Consortium
BUFFALO, NY

Amoako, Patricia
Medicine-Primary
North Shore University
MANHASSET, NY

bosso, Daniel
Emergency Medicine
orth Shore University
MANHASSET, NY

Bax·Debiaso, Sarina
Ge11eral Surgery
SUNY/Buffalo Graduate MedicalDental Education Consortium
BUFFALO, NY

Bellows, Jason
Medicine-Preliminary
George Washington University
WASHINGTON, DC

Emergency Medicine
George Washington University
WASHINGTON, DC

Benedicto, IIberto
Surgery-Preliminary
SUNY/Buffalo Graduate MedicalDental Education Consortium
BUFFALO, NY

16

l 1llalo Physician

S

u

111 111

er 2 0 0 1

�Damian and Kristen Compa will train at the University Hospitals of
Cleveland; he will pursue internal medicine and she, pediatrics.

Azin Shahryarinejad, class of 2002. right,
congratulates Eileen Lau, who is pleased
to be going to the University of Southern
California to train in pediatrics.

Terry Thompson, who received his first choice, celebrates with his wife,
Melissa, and their 14·month·old daughter, Makayla.

Colletti. Richard

Bergfeld, Deborah

Bravin, Marina

Chan. Keith

Physical and Rehabilitation Medicine
McGaw Medical CenterNorthwestern University
CHICAGO, JL

Medicine-Primary
Columbia Bassett
COOPERSTOWN, y

Radiology-Diagnostic
Bridgeport Hospital
BRIDGEPORT, CT

Bui. Hieu

Chan, Mew

Medicir1e-Preliminary
Franklin Square Hospital
BALTIMORE, MD

Pediatrics
Baystate Medical Center
SPRINGFIELD, MA

l11temal Medicine
University Hospitals of Cleveland
CLEVELAND, OH

Buscaglia, Jonathan

Cheung, Barbara

Compa, Kristen

Internal Medicine
Einstein/Montefiore
BRONX, y

Internal Medicine
St. Vincent's Hospital
NEW YORK, Y

Black. Thomas
Pediatrics
SUNY/Buffalo Graduate MedicalDental Education Consortium
BuFFALO, NY

Blyth, Stacey
Family Practice
SUNY/Buffalo Graduate MedicalDental Education Consortium
BuFFALO, NY

Psychiatry
Lama Linda University
LOMA LINDA, CA

Compa, Damian

Pediatrics
University Hospitals of Clevela nd
CLEVELAND, OH

Conboy, Thomas

Butsch, Winfield

Chou, Richard

Internal Medicine
SU Y/Buffalo Graduate MedicalDental Education Consortium
BUFFALO, NY

lntemal Medicine
Ohio State University
Medical Center
COLUMBUS, OI-l

Campbell. Katrin

Chow, Selwyn

Transitional
Akron General Hospital
AKRON, OH

Medicine-Preliminary
Brown University
PROVIDENCE, Rl

Botta, Thomas

Cancilla. Laura

Cicero, Mark

Internal Medicine
New York Presbyterian Hospital
NEw YoRK, Y

Internal Medicine
University of Rochester/Strong
Memorial Hospital
ROCHESTER, NY

Pediatrics
Eastern Virginia Medical School
NoRFOLK, VA

Borgoy, John
Medicine- Preliminary
Lankenau Hospital
WYNNEWOOD, PA
Emory University School of
Medicine
ATLANTA, GA

Bourne, Ryan
Internal Medicine
SUNY/Buffalo Graduate MedicalDental Education Consortium
BuFFALO, Y

Bowman, Daniel
Orthopaedic Surgery
Albany Medical Center
ALBANY, Y

Braun, Amy
Pediatrics
SUNY/Buffalo Graduate MedicalDental Education Consortium
BuFFALO, NY

Clark, Kristin
Carrero, Albert
Anesthesiology
SUNY/Buffalo Graduate MedicalDental Education Consortium
BUFFALO, NY

Chan, Audrey
Medicine- Preliminary
Pennsylvania Hospital
PH ILADELPHIA, PA
Ophthalmology
University of Maryland
BALTIMORE, MD

Medici 11e-Preli m ina ry
SU Y/Buffalo Graduate MedicalDental Education Consortium
BuFFALO, NY
Radiology- Diagnostic
SUNY/Buffa lo Graduate MedicalDental Education Consortium
BUFFALO, NY

Clementi, Jennifer
Pediatrics
Long Island jewish Hospital
NEW HYDE PARK, NY

Psychiatry
Duke University Medical Center
DUR II AM, c

Curry, Timothy
Medicine- Prelimi11ary
SU Y/Buffalo Graduate MedicalDental Education Consortium
BuFFALO, NY
Anesthesiology
Mayo Graduate School of Medical
ROCHESTER, MN

Dalewitz, Jessica
Medici11e- Preliminary
Beth Israel Medical Center
EW YORK, NY
Neurology
Albert Einstein College of Medicine
BRONX, NY

Den Haese, Ryan
Neurological Surgery
University of Maryland
BALTIMORE, MD

Diamantis, Pamela
Pediatrics
University of Texas Medical School
HousTON, TX

Summer 200/

l ulf1ID Physiciu

17

�M

E

D

C

A

L

SCHOOL

N

w

Doran, James

Figueroa, Jeanette

Kallen, Dianne

Family Practice
Mercy Hospital
PITTSBURGH, PA

Family Practice
SUNY/Buffalo Graduate MedicalDental Education Consortium
BUFFALO, NY

Family Practice
St. Vincent Health Center
ERIE, PA

Dull, Michael

Dwyer, Cheri
Family Practice
Atlanta Medical Center
ATLANTA, GA

Flood, Jeremy
lntemal Medicine
Thomas jefferson University
PHILADELPHIA,

PA

Kling, Christopher

Pediatrics
SU ¥/Buffalo Graduate MedicalDental Education Consortium
BuFFALO, NY

Medicine-Preliminary
SUNY/Buffalo Graduate MedicalDental Education Consortium
BUFFALO, NY
Derma to logy
St Louis University School of
Medicine
STLOUIS, MO

Psychiatry
Harvard Longwood
BosTON, MA

Emerge11cy Medici11e
SU ¥/Buffalo Graduate MedicalDental Education Consortium
BuFFALO, NY

Obstetrics-Gyr1ecology
SUNY/Buffalo Graduate MedicalDental Education Consortium
BUFFALO, NY

Galas, James

Gilmore. Sasha

Dwyer, James

Kundu, Renita
Gould, Milena
/ntemal Medicine
New England l'vledical Center
BosToN, MA

Ehrig, Debra

Emergency Medicine
Yale-New Haven Hospital
NEw HAVEN, CT

Kurtz, Stacey

Pediatrics
SUNY/Buffalo Graduate MedicalDental Education Consortium
BUFFALO, NY

Greenberg, Barbra
Psychiatry
ew York University School
of Medicine
EW YoRK, NY

Elliott, Frederick
Pediatrics
New York University School
of Medicine
EW YORK,
y

Gross, Kara

Erway, Kimberly

Guyer, Aaron

Psychiatry
University Health Center
PITTSBURGH, PA

Orthopaedic Surgery
University of Michigan Hospitals
ANN ARBOR, Ml

Evanchuk, Darren

Hannahoe, Brigid

illtemal Medicine
McGaw Medical CenterNorthwestern University
CHICAGO, IL

Pathology
Cleveland Clinic Foundation
CLEVELAND, OH

Pediatrics
Einstein/Montefiore
BRONX, NY

Facer, Jeffery
Internal Medicine
SU ¥/Buffalo Graduate MedicalDental Education Consortium
BUFFALO, NY

Falvo, Mark
General Surgery
SUNY/Buffalo Graduate MedicalDental Education Consortium
BUFFALO, NY

Fantuzzo, Joseph
Surgery-Prelimirwry
SUNY /Buffalo Graduate MedicalDental Education Consortium
BuFFALO, NY

luffalo Phys i cian

Kevin Mullen and his wife, Rachel, celebrate his
placement in general surgery at the University
of Pittsburgh's University Health Center.

Kennedy, Suzette

Medici11e Preliminary
SUNY/Buffalo Graduate MedicalDental Education Consortium
BuFFALO, NY
Radiatior1-0ncology
University of Minnesota Medical
School
MINNEAPOLIS, MN

18

E

Pediatrics
Georgetown University Hospital
WASHINGTON, DC

Laprairie, Danielle
Obstetrics-Gynecology
University of Connecticut
FARMINGTON, CT

Lau, Eileen
Pediatrics
University of Southern California
Los ANGELES, CA

Lesh, Charles

Lim Sabina
Psychiatry
Yale-New Haven Hospital
NEW HAVEN, CT

Maness is, Anastasios
Medici11e-Pediatrics
St. Vincent's Hospital
NEw YoRK, NY

Mazzeo, Ramona
Psychiatry
University of Massachusetts
Medical School
WoRCESTER, MA

McConn, Kara
Psychiatry
California Pacific Medical Center
SAN FRANCISCO, CA

lntemal Medicine
SUNY/Buffalo Graduate MedicalDental Education Consortium
BuFFALO, Y

Hughes, Jeffrey

Medicine Preliminary
SUNY/Buffalo Graduate MedicalDental Education Consortium
BUFFALO, NY
Radiology-Diagnostic
Hospital of St. Raphael
NEw HAVEN, CT

Family Practice
St. joseph's Hospital
SYRACUSE, NY

Lewin, Sami

General Surgery
University of Chicago Hospital
CHICAGO, IL

Pediatrics
SU ¥/Buffalo Graduate MedicalDental Education Consortium
BuFFALO, NY

Medici11e-Prelimi11ary
Winthrop-University Hospital
MINEOLA, NY
Radiology-Diagnostic
Mt. Sinai Hospital
NEW YORK, NY

Jobes. Gregory

Lezama, Jennifer

lntemal Medicine
SU ¥/Buffalo Graduate MedicalDental Education Consortium
BUFFALO, y

Psychiatry
SUNY/Buffalo Graduate MedicalDental Education Consortium
BUFFALO, NY

Jobes, Annmarie

Summer

2001

McDonald, Amy

Mezhir, James

Millstein, Leah
Medici11e-Pediatrics
University Hospitals of Cleveland
CLEVELAND, OH

Miralog1u, Didem
Medici 11e-Preli 111 ina ry
Mary Imogene Bassett
CooPERSTOwN, Y
Physical and Rehabilitive Medicine
Eastern Virginia Medical School
NORFOLK, VA

�Ndegwa Njuguna is headed for the
University of Illinois College of Medicine.

Ouilikon, Neva
lr1temal Medici11e
johns Hopkins/Sinai
BALTIMORE, MD

Paa, Kimberly
Mallen, Kevin
Gweral Surgery
University Health Center
PITTSBURGH, PA

Morris, Eleazar
TrallSitiorwl
ew York Hospital/Medical
Center Queens
FLUSHING, Y
A11esthesiology
Mt. Sinai Hospital
NEW YORK, NY

Naik. Dhruti
Pediatrics
SU Y/Buffalo Graduate MedicalDental Education Consortium
BuFFALO, NY

Njuguna, Ndegwa
l11temal Medici11e
University of Illinois College
of Medicine
CHICAGO, IL

O'Brien, Kristen
Family Practice
Stonybrook Teaching Hospitals
STONY BROOK, NY

O'Connor, Thomas
Medici11e-Primary
University of Rochester/Strong
Memorial Hospital
RocHESTER, NY

Odell, Barbara
Medicine-Pediatrics
Penn State
HERSHEY, PA

Ogie. Debra
l11temal Medicine
University of Illinois College
of Medicine
CHICAGO , I L

Orr.Jeremy
Family Practice
University of Colorado School
of Medicine
DENVER, CO

A11esthesiology
SU Y/Buffalo Graduate MedicalDental Education Consortium
BUFFALO, NY

Park, James
lrttemal Medicine
New York University School
of Medicine
EW YORK, NY

Pasamba, Bernadette
Medici11e-Prelimirwry
Einstein/Montefiore
BRONX, y
Anesthesiology
ew York Presbyterian Hospital
EW YORK, NY

Peters, Elyssa
Medicine- Prclimirwry
Abington Memorial Hospital
ABINGTON, PA
Ophthalmology
Temple University
PHILADELPHIA, PA

Pfalzer, Aaron

Plumpton, Jessica

Swiencicki, James

Pediatrics
Wright Patterson, AFB
DAYTON, OH

Medicine-Primary
Metrohealth Medical Center
CLEVELAND, OH

Rakhlin, Aleksandr

Syed, Sufia

Gweral Surgery
Westchester Medical Center
VALHALLA, NY

l11temal Medici11e
George Washington Universtiy
WASHINGTON, DC

Reynolds, Deborah

Thompson, Terry

l11temal Medici11e
Mt. Sinai Hospital
NEw YORK, Y

Family Practice
Lynchburg Family Practice Center
LYNCHBURG, VA

Salerno, Kilian

Trapp, Kathleen

Emergwcy Medici11e
SUNY/Buffalo Graduate MedicalDental Education Consortium
BUFFALO, NY

Family Practice
SU Y/Buffalo Graduate MedicalDental Education Consortium
BuFFALO, NY

Samanich, John

Trebb, David

Psychiatry
Beth Israel Medical Center
NEw YoRK, NY

Pediatrics
Brooke Army Medical Center
FoRT SAM HousTON, TX

Sarpel, Umut

Trojan, Christopher

General Surgery
Mt. Sinai Hospital
NEw YoRK, Y

Radiology-Diagrzostic
William Beaumont Hospital
ROYAL OAK, Ml

Medici 11e-Preli111 i 11ary
SUNY/Buffalo Graduate MedicalDental Education Consortium
BuFFALO, Y
Radiology-Diag11ostic
SUNY/Buffalo Graduate MedicalDental Education Consortium
BUFFALO, y

Setlik, Robert

Yakani, Rajesh

1111emal Medici11e
Brooke Army Medical Center
FoRT SAM HousToN, TX

Medici ne-Pedia 1rics
Albany Medical Center
ALBANY, NY

Seelagan, Davindra

Emerge11cy Medici11e
SUNY/Buffalo Graduate MedicalDental Education Consortium
BUFFALO, Y

Shaposhnikov, Rimma

Werth, Christopher

l11temal Medici11e
University of Southern California
Los ANGELES, CA

Surgery-Prelimi11ary
SUNY/Buffalo Graduate MedicalDental Education Consortium
BuFfALO, NY

Philip, Joey

Sharma, Mudit

Medici11e-Prclimirwry
SU Y/Buffalo Graduate MedicalDental Education Consortium
BuFFALO, NY

Surgery-Prclimirwry
Georgetown University Hospital
WASHINGTON, DC
Neurological Surgery
Georgetown University Hospital
WASHINGTON, DC

Pickhardt, Donald
Pediatrics
SUNY/Buffalo Graduate MedicalDental Education Consortium
BuFFALO, NY

Pietryga, Michelle
Psychiatry
Harbor UCLA Medical Center
TORRANCE, CA

Pigos, Kevin
Family Practice
Williamsport Hospital
WILLIAMSPORT, PA

Sisser. Eve
Psychiatry
Long Island jewish Hospital
NEW HYDE PARK, NY

Steiding, Karena
Pediatrics
Yale- New Haven Hospital
NEW HAVFN, CT

Woolever, Amy
Pediatrics
Einstein/Montefiore
BRONX, NY

Wychowski, Adam
Medici11e-Pediatrics
Baystate Medical Center
SPRINGFIELD, MA

Yates, Robin
Pediatrics
New York University School
of Medicine
NEw YoRK, NY

Zalar, Mona
PEDIATRICS
New England Medical Center
BosTON, MA

Summer 2 001

Bu ff

1

I o Physic i 1 n

19

�==,
I

CAT Program Returns to Buffalo
Focus on biomedical and bioengineering technologies

f lt.R 1\lF \RIY A DH. A.DF without a New York State Center for

programs available to partners of such centers,

Advanced Technology (CAT) program that supports industryuniversity collaborations to drive job creation and economic
growth, Buffalo is once again home to a CAT, this time a joint
venture between the University at Buffalo and Roswell Park

explains Holm, adding, "that's why it was so important to get this formal designation."

Cancer Institute (RPCI).
At a press conference held on April 30, 2001, at RPCI, Governor George E. Pataki announced the new Center for Advanced
Technology in Biomedical and Bioengineering Technologies
along with $1 million in funding for the center. There are 14 other
such centers around the state, each of which receives $1 million in
funding annually.
Noting that the elimination of Buffalo's CAT in the early 1990s
"sent the wrong message" about UB and Western New York, Pataki
said that the redesignation of the CAT program will have a tremendous impact on the people of Western New York by fostering
the creation of new biotechnology start-up companies and by helping existing biomedical businesses to expand through new or im-

v

G

The Center for Advanced Technology in Biomedical and Bioengineering Technologies will focus on developing new products
and creating new jobs in Western New York from biomedical and
bioengineering research conducted at UB, RPCI and Western New
York companies. Robert]. Genco, DDS, PhD, SUNY Distinguished
Professor and chair of the Department of Oral Biology in the
School of Dental Medicine, was named director of the center.
Genco explains that the Center for Advanced Technology in
Biomedical and Bioengineering Technologies will fund projects
that are close to the commercialization stage. Particular emphasis
will be placed on two areas in which Buffalo researchers have traditionally excelled: the development of biopharmaceuticals, such as
the PSA test for prostate cancer, lung-surfactant therapy-for premature infants, photodynamic-cancer therapy and interferon treatment

for UB and RPCI by several years, explains Bruce Holm, PhD, senior

for multiple sclerosis; and biomedical devices, such as the implantable
pacemaker and the platinum coil for inoperable cranial aneurysms.
According to Genco, the center will take advances like these and help
ensure that they not only are developed in Western New York, but also

associate vice president for health affairs. "We assumed we'd have to
wait until 2004 to apply formally when the next round of com-

produced and manufactured here once they are commercialized.
In addition, he says that the Center for Advanced Technology in

petition for a CAT becomes available," he says. "The governor's

Biomedical and Bioengineering Technologies will function as the
science-transfer and accelerator arm of other new centers that are fund-

proved product lines.
The governor's announcement shortened the formal CAT process

announcement shortens the timeline by three years."
The announcement also makes UB eligible for any and all state

2 0

B

ELLEN
0 L 0 8 Au M

1111111 Pbysiciaa

S um me r

2 0 0 1

ed in Western New York, such as the new NYSTAR center (see article,

�State companies may compete for two different types of awards,

Research Milestone

which will be in the range of $100,000 to $200,000 per project.

NYSTAR Program announced by governor

opposite) and the proposed Center of Excellence in Bioinformatics.
Researchers at UB and RPCI, in collaboration with ew York

Discovery Awards are made for innovative projects that use a
bioinformatics-type approach that allows researchers

Particular emphasis will
be placed on two areas
in which Buffalo
researchers have
traditionally excelled:

to "leapfrog" from a basic-science level to a develop-

~ MA'r 3,200l, GovernorGeorge

Bv

ment stage. Science Transfer Awards are for research

E. Pataki came to the University at

ELLEN

that is nearly ready for commercialization.

Buffalo School of Medicine and Bio-

GOLDBAUM

"The Discovery Awards typically will fund re-

medical Sciences to announce that UB and its research

search that uses a genomic or bioinformatics ap-

partners have received three peer-reviewed grants total-

proach," explains Genco. "Say a researcher has an idea

ing $25 million from the New York State Office of Sci-

for a diagnostic test or a treatment target. By asking

ence, Technology and Academic Research (NYSTAR).

a very practical question, and by doing very rapid

Calling the funding one of the largest high-

the development of

throughput screening and analysis with the DNA

technology/biotechnology-related investments ever

biopharmaceuticals.

microarray or on the computer, the scientist can very

made by the state in the Buffalo area, Pataki said the

quickly come up with some good candidate com-

amount constituted one-fourth of the total funding
awarded throughout the state under the NYSTAR program .
"This new STAR center in Buffalo represents a major milestone

and biomedical devices.

pounds for drug targets or diagnostic tests."
Science Transfer Awards will be made to research-

ers who have something in late-stage development that
requires additional testing.
"This type of award has been the missing link for our researchers," Genco notes. "Government agencies won't fund such projects
because they're not true 'discovery research' and often companies
want this kind of 'proof-of-concept' work to have already been
completed. The Science Transfer Award will facilitate the next
step, which could be either solicitation from venture-capital
companies or major funding from industry. We're particularly
excited because the CAT fills that niche."

in our efforts to foster the growth of high-tech and biotechnology
research and economic development throughout New York State,"
Pataki said. "This new center-when combined with our $1 billion
Centers of Excellence plan-will generate significant new research
funding and spur the establishment of spin-off enterprises, bringing
new jobs and economic opportunities to Western New York."
The most substantial of the three competitive awards granted
was $15.3 million allocated for the establishment of the new Strategically Targeted Academic Research (STAR) Center for Disease

For more information on the Center for Advanced Technology

Modeling and Therapy Discovery. The center is a partnership between UB, Roswell Park Cancer Institute, Hauptman-Woodward

m Biomedical and Bioengineering Technologies, contact Dr.

Med ical Research Institute and Ka leida Health. The corporate

Genco at (716) 829-2854; or at rjgenco@buffalo.edu.

CD

.

0

partner is IBM Life Sciences Division, and Bruce Holm, PhD,

Summer

2001

l af falt Pbys i c i aa

2 1

�senior associate vice president for health affairs at UB, is principal
investigator for the award.
The Center for Disease Modeling and Therapy Discovery is
designed to make Western New York a world-class player in a broad
range of new scientific fields made possible by the sequencing of the

ew York."

The strategy involves developing an academic-industry colocator facility in the vacant 50,000-square-foot Westwood
Squibb Pharmaceutical building at 100 Forest Avenue in Buffalo.
The co-locator will facilitate prototyping of new products and

human genome. Its ultimate purpose is to discover and develop new
drugs and clinical therapies using the tools made possible by the

commercialization of research by providing laboratory and busi-

genomics revolution and to bring them to the marketplace.
An additional $8 million in NYSTAR funding was awarded to

from academic and industry, as well as UB Business Alliance staff.

UB's Institute for Lasers, Photonics and Biophotonics, under the
direction of Paras Prasad, PhD, SUNY Distinguished Professor in

locally, but throughout the state- through establishment of a
"virtual collaboratory" with the IBM Life Sciences Computational

the Department of Chemistry, as part of a $14 million information

Biology Division. The virtual collaboratory developed and proto-

technology research center awarded to Rochester Institute of

typed by UB faculty members is an innovative informatics concept

Technology. University at Buffalo researchers led by Robert E. Baier,

that makes possible ubiquitous telecommunications between all

PhD, professor of oral diagnostic sciences and director of
the Industry/University Center on Biosurfaces, and George Lopos,
PhD, dean of Millard Fillmore College, also received funding

participating institutions. An additional economic engine for
Western New York, this concept already has resulted in the forma -

totaling $1.5 million as part of the New York Environmental
Quality Systems Center established at Syracuse University.

ness-incubation space to a multidisciplinary group of scientists
The center will forge numerous links with partners-not just

tion of a spin-off company, Visual Design Systems.
The virtual collaboratory concept means that for the first time

"It's a win-win situation for UB, its partners and the entire

in Western New York, different institutions will be linked
through Internet 2, the high-bandwidth portion of the Internet

Western New York community, which will benefit greatly from
new job creation in the biomedical field," said }aylan Turkkan, UB

reserved for computationally intensive research. Already functioning on and between UB's North and South campuses,

vice president for research. "Through our plans for virtual collabora-

Internet 2 communications require the installation of so-called

tories and academic-industry co-location, our researchers will be

"dark fiber" connections, funding for which will be provided by
the NYST AR award.

integrated with industry in a way they never have been before."
Holm noted that the awarding of the grant speaks highly of the
quality of science being conducted by UB and its partners. "The fact
that this gran t was awarded based on a peer-review process demon-

"This will connect not only institutions in Western New York,
but all across the state," said Holm.
"And our experience in the past six months has been that even

strates that the quality of science already being done in Western New

just the possibility of having this type of connection has clearly

York meets a particularly good standard," he noted. "We are opti-

turned heads. To connect not only to faculty in the region, but to

mistic that with this funding and with the plan that actually formu-

have access to the intellectual capital all across the state has been a
very strong draw."
4D

lated the funded proposal, we will be able to accelerate both the

22

academic science and the corporate science in Western

I u II a I o P b JS i cia n

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111 111

er

2 0 0 I

�Buffalo-Niagara Medical Campus
New group formed to coordinate projects

HE MAJOR PL \\ ERS IN ~1EDJCAL CARE, research, educa-

Bv

fruition. "In my 20 years as a volunteer in health care

tion and biotechnical innovation concentrated in what has been

L

0 Is

around the High Street area, this is the best I have ever

BAKER

seen the institutions communicate and work with one

termed the "High Street medical corridor" in Buffalo have formed
an entity called the Buffalo-Niagara Medical Campus (B MC) to

another," Beecher says. "It is encouraging to see the 'silo mentality'

coordinate projects that will serve and enhance the group as a whole.

disappear, which in the past has isolated individuals and groups

Thomas R. Beecher, chair of the group's board of directors, announced the formation of the BNMC at a press conference held on
April 30, 2001, at Roswell Park Cancer Institute (RPCI).

from one another, thus making partnerships more difficult."
The BNMC has adopted three goals that will drive its work in the
future: Create a world-class medical campus that enhances the

The members are the University at Buffalo, RPCI, Kaleida Health,

already existing clinical, research and teaching excellence of the

Hauptman-Woodward Medical Research Institute (HWJ) and the
Buffalo Medical Group Foundation. The City ofBuffalo, Erie Coun-

member institutions; create economic-development opportunities;
and improve and expand the infrastructure of the current campus.

ty and the adjoining neighborhoods of Allentown and the Fruit Belt

The work is being funded by contributions from the Oshei Founda-

are partners in the effort. The entity is governed by a 14-member

tion and the five member institutions. Active since December 2000,

board of directors composed of representatives from the institutions

the group has a project director, Matthew K. Enstice, and has
accomplished a number of tasks, including contracting with UB's
Center for Computational Research to create a virtual medical
campus for use in research collaborations, economic development
and faculty recruitment.

and partners. UB is represented by President William R. Greiner and
Michael E. Bernardino, MD, MBA, vice president for health affairs
and dean of the School of Medicine and Biomedical Sciences.
Each institution retains its independent governance while collaborating on campus activities. They are being supported in their
efforts by a loosely organized Trustee Council composed of corpora-

While UB doesn't own land or structures on the medical campus,

tions, businesses, government agencies and nonprofit organizations

it has a major presence there through its faculty and research. UB's
new Department of Structural Biology is located within HWJ, and

that are asked to provide volunteer help and consultation as needed.
The purpose of the B MC, according to Beecher, is to support the

HWI scientists are on the department's faculty. The university and
RPCI are joint operators of the DNA microarray facility, many

needs of the member institutions as they work to form a world-class

RPCI faculty have UB appointments, and UB's cancer research and

medical campus that supports centers of excellence in research,

teaching is carried out there. Moreover, Kaleida Health is UB's

education and clinical care. He praised the synergy and cooperative

largest medical-care teaching affiliate, and many members of the

spirit of the BNMC members in bringing the collaboration to

Buffalo Medical Group serve as UB clinical faculty members.

Summer

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Buffalo Physician

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Commencement 2001
Commencement for the University at Buffalo School of Medicine
and Biomedical Sciences was held on May 18, 2001. This year, the
school conferred 125 MD degrees, 2 MD/PhD degrees, one MD/MBA
degree, 33 PhDs and 42 master's degrees.
Pictured (1) Honored Speaker Ronald Dozoretz, MD '62 (2) Kathleen
Trapp with children Will, Anne and Joseph (3) Dean John R. Wright, MD
(4) Kristen A. O'Brien (5) Jeanette Figueroa and third·year student
Pamela Livingston (6) Patricia lmoako (7) Timothy B. Curry, MD, PhD
(B) left to right, Mark Cicero, Ndegwa Njuguna and Jennifer Lezama.
The following excerpts are from the commencement speech given by
this year'shonored speaker Ronald I. Dozoretz, MD '62, chief executive
officer, chair and founder of FHC Health Systems.
"Set your sights high-be braced and sure-footed on your
journey. The possibilities before you in this remarkable
time are infinite. With new technologies and understanding from initiatives like the Human Genome
Project, you have the capability to make breakthroughs
I could only dream of when I was in school."
"And I challenge you not only to be bold and take chances
in the field of medical science, but in the social sciences
as well. Do not leave this very important responsibility to
someone else . ... I am sure you are aware of the billions
of dollars given to teaching institutions and research
projects each year by local, state and especially the
federal government. Be involved so you can help influence
their decisions."
"Few people will ever have such a magnificent opportunity
to help society. You have an obligation to do so-seize it.
There are many challenges that we face collectively: one
in six children live in poverty in this country. There are
44 million Americans without health insurance. Public
schools in most cities are in poor repair, and students have
no books. AIDS in Africa threatens the future of the
entire continent.
"We as a nation and as a people must address these
challenges. And with your expertise, society will look to
you for leadership."
"As you embark on your journeys in the world of
medicine, research and teaching, please follow your
dreams and don't be afraid to fail. Take chances. Be bold.
Be passionate. Give back to your community But most
important: Never give up. Never give up. Never give up."

Summer

2001

��PATHWAYS

N Ews ABOUT UB' s ScHOOL oF M E DICINE AND BIOM EDICAL S c i EN CES
AND I TS ALU MNI, F AC U LT Y, S T UD ENTS AND STAFF

M

Paroski Named
Director of
Admissions
Margaret W. Paroski, MD '80,
has been named director of
admissions for University at
Buffalo's School of Medicine
and Biomedical Sciences. She
succeeds Thomas
Guttuso, MD '60, who
served in this capacity
at UB for 19 years.
Paroski is professor of clinical neurology at UB and
medical director for
A RGA RE T P A R os KI Erie County Medical
Center, a position she
will continue to hold. She served
as president of UB's Medical
Alumni Association in 1996
and is president-elect of the
UB Alumni Association. Currently, Paroski is a member of
the Dean 's Advisory Council
for the School of Medicine and
Biomedical Sciences.

Guttuso joined the Admissions Committee in 1977 and
was named director of
admissions in 1982. He has
also served as acting chair of
the school 's Department of
Ophthalmology.
- S.A .

UNG ER

Bojovic Selected for
Medical Mission
Branko Bojovic, Class of 2002,
has been selected as a medical
student participant on an international medical mission
sponsored by Operation Smile.
Medical students are chosen
via a competitive application
process, and Branko is the first
University at Buffalo student
ever selected for this prestigious opportunity. Approximately 20 medical missions are
sponsored by "Op Smile" each
year to over 20 countries,
where free facial reconstruc-

tive surgery repairs are provided to the medically needy, most
of whom are children.
- D E BR A STAMM

Miller to Head
Division of Child and
Adolescent Psychiatry
Following a national search,
Bruce Miller, MD, associate
professor of psychiatry and
pediatrics in University at
Buffalo 's School of Medicine
and Biomedical Sciences, has
been named director of the Division of Child and Adolescent
Psychiatry at UB. He succeeds Gary
Cohen, MD,
associate
professor of
clinical psychiatry, who
founded the
division
in 1978 and CA RY CO H EN

has served as its director for
the past 23 years.
Miller, who joined UB 's
faculty six years ago, is a national authority on emotional
factors impacting on childhood
asthma. He received his medical
degree from the
College of Medicine and Dentistry
of New Jersey. He
served as an intern
in medicine at
B RUC E MILLER
Long Island Jewish/Hillside Medical Center in New Hyde Park,
New York, and completed his
residency tra ining in general
psychiatry and child and
adolescent psychiatry prior to
completing a postdoctoral research fellowship in developmental psychobiology at the
University of Colorado Health
Sciences Center. Miller served

MILLER, A NATIONAL AUTHORITY ON EMOTIONAL FACTORS IMPACTING ON CHILDHOOD
ASTHMA, SUCCEEDS GARY COHEN, MD, ASSOCIATE PROFESSOR OF CLINICAL PSYCHIATRY, WHO
FOUNDED THE DIVISION IN

26

I u If a I a Phy si c i an

S umm er

1978

2 001

AND HAS SERVED AS ITS DIRECTOR FOR THE PAST

23

YEARS .

�on the faculty of the University
of Colorado for nine years before being named director of
the Division of Child and Adolescent Psychiatry at the University of Rochester. Prior to
his accepting the position of director ofUB's Division of Child
and Adolescent Psychiatry, he
served as the director of pediatric psychiatry at Children's
Hospital of Buffalo, a position
he will continue to hold.
Since coming to Buffalo, Miller
and his research team have been
awarded over $2 million in
federal grant support for

government payers and patients
will routinely use to make
health-care decisions.
"To see ECMC listed as a
Top 100 Benchmark Hospital
in two out of four specialized
areas included in this national
study is a proud achievement
for our hospital," says Sheila K.
Kee, chief executive officer at
ECMC. "T his recognition
serves as yet another confirmation of the outstanding quality
care that is offered by the
Western ew York region's
medical center."
-S.A.

UNGER

their research.
-S.A.

UNGER

ECMC's
Cardiovascular and
ICU Services Top 100
Modern Healthcare magazine
has cited the Erie County Medical Center (ECMC)-a major
teaching facility for University
at Buffalo-as one of the 100
top hospitals for cardiovascular and intensive care services
in the United States, according
to an independent study conducted by Solucient (formerly
HCIA-Sachs Institute) healthcare information company.
The magazine's February26,
2001, issue features Solucient's
100Top Hospitals program that
examines clinical, financial and
operational data from hospitals
to establish benchmarks for
excellence. Clark Bell, editor of
Modern Healthcare, noted that
the study has evolved into a
legitimate tool that employers,

CraigVenter Delivers
2001 Cori Lecture
J. Craig Venter, PhD, president
and chief scientific officer for
Cetera Genomics delivered a
talk on "Sequencing the Human Genome" at the 24th annual Cori Lecture at Roswell
Park Cancer lnstitute (RPCI)
held on May 23, 2001. Venter,
who was on the faculty at the
University at Buffalo School of
Medicine and Biomedical Sciences and RPCl from 1982 to
1984, has been widely recognized as the scientist who led
the team at Celera Genomics
in sequencing the human genome. He has published more
than 160 research articles and
is one of the most cited scientists in biology and medicine.
He has received a number of
honorary degrees for his pioneering work and was selected as Man of the Year by the
Financial Times.

The Cori
lecture honors Drs.
Carl and
Gerty Cori,
who served
on RPCl's
faculty from
J.

CRAIG VENTER

1922 until
1933. During this time, they
initiated work on the chemis-

try of the glycogen-glucose
cycle, research that earned
them the 1947 Nobel Prize in
Physiology and Medicine.
With this honor, Gerty Cori
became the first American
woman and the third woman
in the world to be awarded the
Nobel Prize.
-DEBORAH PETTIBONE

Ceorge M. Ellis .Jr.,
MD '45, Receives
Samuel P. Capen Award
George M. Ellis Jr., MD '45, received the Samuel P. Capen
Award-University at Buffalo
Alumni Association's most
prestigious prize-at a dinner
held on April 20, 2001, in the
Center for Tomorrow on the
north campus. Ellis, a generous
and devoted alumnus of the
School of Medicine and Biomedical Sciences for half a
century was presented the
honor for his notable and
meritorious contributions to
the university and its family.
Prior to his retirement, Ellis
worked as a physician and surgeon in a small, semi-rural
Indiana community. He established the George M. Ellis Jr.,

S

11 111 111

MD, Endowment Fund for
Medicine at UB, and also donated a rare, first edition of
De conceptu et generatione
homin11s-written by Jacob
Rueff and published in Zurich
in 1554-to mark the university library's acquisition of its
three-millionth volume.
Since his graduation from medical
school, Ellis has devoted countless hours
to organizing annual
reunions for the class
of 1945 as well as to
keeping his classGEORGE M.
mates updated and
informed about each other.
Last year, at the class's 55th
reunion, he compiled a book
that featured a biographical
sketch of each class member.
"The book is a treasured
piece of memorabilia for each
of his classmates and the families of those no longer with
us," says Mary Glenn, director
of community relations for
the School of Medicine and
Biomedical Sciences.
-S.A .

ELLIS

UNGER

Beutner and .Jordon
Honored for Research
Ernst Beutner, PhD,
professor emeritus of
microbiology and
dermatology at the
University at Buffalo
School of Medicine
and Biomedical Sciences, and Robert E.
Jordon, MD '65, chair

e r 200 I

ERNST H. BEuTNER

Buffalo Physician

27

�PATHWAYS

"THE WORK OF DRS. [ERNST

H.]

BEUTNER AND [ROBERT E .] JORDON ESSENTIALLY BEGAN

THE MODERN ERA OF DERMATO-IMMUNOLOGY," SAYS DERMATOLOGY fOUNDATION PRESIDENT
JouNI J. UITTO, MD, PHD, IN PRESENTING THE SCIENTISTS WITH THE DISCOVERY AWARD.

of the Department of Dermatology at the University of
Texas Medical School at
Houston, were chosen as corecipients of the Dermatology
Foundation's 2000 Discovery
Award at the annual meeting
of the foundation on
March 3, 2001, in
Washington. D.C.
The Discovery
Award was created
by the Foundation's
Trustees in 1991 as
the specialty's highest tribute to those
colleagues who embody the essence of scientific and intellectual curiosity that the foundation strives to nurture through
its research awards program.
Drs. Beutner and Jordon
were honored for their seminal
recognition of the role of autoantibodies in the pathogenesis of pemphigus vulgaris
(PV). Together, they found
that PV autoantibodies bind to
the surface of keratinocytes in
precisely the same suprabasilar
location that PV bullae form,
suggesting a direct pathogenic
role for antibodies.
"The work of Drs. Beutner
and Jordon essentially began
the modern era of DermatoImmunology," says Dermatology Foundation President

Jouni J. Uitto, MD, PhD. "The
clarity of the relationship between bullous disease manifestations and laboratory
findings, first established by
[them] has not only permitted
important aspects of pemphigus pathogenesis to be
deciphered but has helped
frame the next set of research
challenges."
Beutner joined UB's faculty
in 1956 and taught microbiology to students of medicine
and dentistry until his retirement in 1994. In 1992, he became director of Beutner
Laboratories in Buffalo.
The UB School of Medicine
and Biomedical Sciences is
proud that a faculty member
and alumnus are corecipients
of this prestigious award.
-S. A.

UNGER

Lema Leads State
Anesthesiology
Society
Mark J. Lema, MD, PhD, professor and interim chair of the
Department of Anesthesiology
at University at Buffalo's
School of Medicine and Biomedical Sciences, has been installed as president of the New
York State Society of Anesthesiologists (NYSSA), a chapter
of the Society of Anesthesi-

ologists. Lema is also chair of
the Department of Anesthesiology and Pain Management at
Roswell Park Cancer Institute
(RPCI) and associate research
professor in the Experimental
Pathology Program at RPCI.
As head of NYSSA, Lema
leads a community of approximately 3,000 New York State
anesthesiologists and works
closely with the national organization, which boasts a membership of more that 37,000
anesthesiologists. In addition to
his new role with NYSSA, Lema
is editor of the journal Regional
Anesthesia and Pain Medicine,
the American Society ofAnesthesiology Newsletter, special editor
of SPHERE and associate editor
of the Clinical journal of Pain.
He is a member of the Cancer
Pain and
End -of-Life
Care panels
of the NationalComprehensive
Cancer
Network, a
MARK J. LEMA
member of
the Cancer
Pain Guidelines Panel of the
American Pain Society, and
serves on the New York State
Commissioner of Health' s
Preoperative Policy Panel.
- DEB OR AH PETTIB ON E

28

lu lfal a Pb ysicin

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2 001

Bakshi Named
Associate Professor
Rohit Bakshi, MD, has been
named associate professor of
neurology with tenure in the
clinical-scholar track
in the University at
Buffalo's School of
Medicine and Bio medical Sciences.
A native of Buffalo, Bakshi received
his medical degree
from UB in 1991. As RoHIT BAK SHI
an Alpha Omega Alpha scholar, he completed a
neuroscience research fellowship with Alan Faden, MD, at
the University of California at
San Francisco, where he studied neuropharmacology and
stroke. Following medical
school, he served a one-year
internship at the Massachusetts General Hospital and a
neurology residency at the
University of California at Los
Angeles. He then completed a
one-year MRI/CT neuro imaging fellowsh ip at the Dent
Neurologic Institute in Buffalo, followed by additional
training in functional imaging.
Bakshi, a staff neurologist
and neuroimager with Kaleida
Health System, is board certified in neurology and is a diplomat of the American Society
ofNeuroimaging. His research

�and clinical interests include
neuroimaging as it relates to
neurologic diseases, especially
multiple sclerosis (MS). Recently, he was awarded a threeyear $350,000, research grant
from the National Institute of
Neurological Disorders and
Stroke to study iron deposits
and atrophy in the brains of
patients with MS using computer analysis of magnetic
resonance imaging scans. The
project is being conducted at
the Buffalo
euroimaging
Analysis Center, part of the
Jacobs Neurological Institute
at Buffalo General Hospital
and the UB Department of
Neurology. Bakshi's previous
work suggests that iron deposition is common in MS
brains and that the level of
iron is related to impairments
in physical disability and brain
atrophy. Since increased iron
levels are known to cause brain
injury in other diseases, his
work raises the possibility of a
new treatment for MS.
-S. A.

UNGER

Robert A. Bermel
Receives the C. Milton
Shy Award
Robert A. Bermel, a secondyear student at the University
at Buffalo
School of
Medicine
and Biomedical
Sciences,
has received the G.
ROBERT A. BERMEL
Milton Shy

Galpin Heads Pediatric Orthopaedic Surgery at Kaleida
OBERT

D.

GALPIN,

MD, has been named chief of the Division of Pediatric

Orthopaedic Surgery at Kaleida HeaHh System's Children's Hospital of Buffalo,
and associate professor in University at Buffalo's Department of
Orthopaedic Surgery. Galpin earned his medical degree from the
University of Western Ontario, London, Ontario, Canada, where he also
completed his orthopaedic surgery residency. Galpin brings with him
over 13 years of experience in pediatric orthopaedic surgery. Prior to
joining Kaleida HeaHh System and UB, he was clinical assistant professor of orthopaedic surgery and pediatrics at the University of

ROBERT

D.

GALPIN

Western Ontario. His clinical interests include the treatment of spinal
deformities, limb lengthening, pediatric trauma, sports medicine and hip and foot
conditions. Galpin is a diplomat of both the American Board of Orthopaedic Surgery and
the National Board of Medical Examiners. He is also a member of Alpha Omega Alpha
Honor Medical Society and the Pediatric Orthopaedic Society of North America.

Award from the American
Academy of eurology.
The award, which recognizes the best essay in clinical
neurology, was presented to
Bermel on May 8, 2001, at the
academy's annual meeting in
Philadelphia, Pennsylvania.
"I am honored to receive
this award from the academy
and am grateful to my mentors, Rohit Bakshi, MD, and
Lawrence Jacobs, MD, for
their guidance in my pursuit
of a career in academic medicine," said Bermel.
"This award is just one
recognition of the world-class

research which continues to go
on in Buffalo in the battle
against multiple sclerosis."
Bermel is continuing his research on neuroimaging in MS
this summer with Bakshi at
the Buffalo Neuroimaging
Analysis Center in Buffalo
General Hospital.
His work will be funded by
student grants from Alpha
Omega Alpha Medical Honor
Society and the UB Research
Foundation.
-S. A.

Varma Selected to
Participate in Mead'-'ohnson Seminar
Chelikani Varma, MD, clinical
associate professor of pediatrics at the University at Buffalo
School of Medicine and Biomedical Sciences, and an
attending at Kaleida Health's
Children's Hospital of Buffalo,
was nationally selected to
participate in the MeadJohnson Clinical Seminar in
April2001 in Tucson, Arizona.
-S.A. UNGER
(I)

UNGER

Slimmer

200/

1 111211 Hysiciu

29

�the 64th

An (xamination of "The Healthy Heart"
Diagnoses and treatment of cardiovascular disease

NIVERSITY AT BUFFALO School of

BY
S

Medicine and Biomedical Sciences' 64th

A.

US G E R

Annual Spring Clinical Day was held April 28, 2001,
at the Buffalo-Niagara Marriott. The program, sponsored by UB's Medical Alumni Association, focused
on "The Healthy Heart" and featured expert speakers who presented state-of-the-art information on
the diagnoses and treatment of cardiovascular disease.
The program opened with a talk on
"Exploring the Power of Cardiac PET
in Mainstream Clinical Practice," by
Michael E. Merhige, MD, UB clinical
associate professor of nuclear medicine
and director of the Nuclear Cardiology
Fellowship Program in the Department
of Nuclear Medicine.
"Interventional Cardiology in the Year
2001" was the title of the next talk, delivered by John C. Corbelli, MD '79, FACC,
FACP. Corbelli is the Lipid Clinic and
Research Director with Buffalo Cardiology and Pulmonary Associates, P .C.,
and clinical instructor at UB.

30

lalfalo Pbysiciaa

S 11mm er

20 0/

Following Corbelli, Paul C. Kerr, DO,
FACS, UB clinical instructor in the
Department of Cardiothoracic Surgery,

spoke on the subject of "Minimally
Invasive Heart Surgery."
After a brief break, the Stockton
Kimball Lecture was delivered by
Antonio M. Gotto Jr., MD, DPhil, the
Stephen and Suzanne Weiss Dean and
Professor of Medicine at Weill Medical
College of Cornell University in New
York City and provost for medical affairs
at Cornell University. Gotto, who is also
past president of the American Heart
Association, spoke on "Perspective on the
Role of Statins in Health and Disease."
Prior to becoming dean of the medical
college at Cornell, Gotto spent over twenty years at Baylor College of Medicine in
Houston, Texas, where he was professor
and chair of the Department of Medicine
and chief of the Internal Medicine Service

�at the Methodist Hospital in Houston .
During that time, he was also]. S. Abercrombie Professor Chair for Athero sclerosis and Lipoprotein Research and
was the scientific director of the DeBakey
Heart Center at Baylor.
Gotto and his associates were the first
to achieve complete synthesis of a plasma
apolipoprotein (apo C-1) and also determined the complete eDNA and amino
acid sequence of apo B-100, one of the
largest proteins ever sequenced and a key
to atherosclerosis and coronary heart
disease (CHD).
In addition to his research interests,
which have brought him worldwide
repute as a leading expert on statins,
Gotto brought to his lecture his clinical
expertise on the pathology of atherosclerosis and CHD.

He began his talk with
a historical overview of
the role of statins in reducing the risk ofCHD,
explaining how the
drugs were subject to a
"backlash" controversy
following their approval by the U.S. Food and
Drug Administration
in 1987. As an example
of this backlash, he described a cover story
published in the September 1989 issue of
the Atlantic Monthly in
which it was contended
that the prescribing of
statins amounted to a
"conspiracy theory."
Following this introduction, Gotto described the statins currently
approved for use in the
United States. In addition to explaining their
mechanism of action,
he outlined data currently available from five major clinical
trials on the effect of statin therapy on
CHD, which, he said, "show a relative
risk reduction over the course of the
trials." Results from these trials, he added, are remarkably consistent and provide
"overwhelming evidence that statins
stabilize plaque," reduce levels of LDL
and reduce cardiac events.
Gotto also described potential new
targets for statin therapy, including diabetes, osteoporosis, stroke and dementia.
While the drugs' efficacy in reducing risk
for these conditions has not been demonstrated in clinical trials, studies are beginning, he explained.
In concluding, Gotto said that, given
statins proven effectiveness in reducing
risk for CHD, he believes there is a
"great underuse" of the drugs. Currently,

10 million Americans take statins, he noted, adding that, in his opinion, "some 25
to 30 million would benefit from them."
At the close of Gotto's lecture, the
audience had an opportunity to ask questions of a panel made up of all the morning's speakers, after which attendees
gathered for a luncheon, where Gotto was
presented the Stockton Kimball Award by
John ]. Bodkin II, MD '76, president of
the UB Medical Alumni Association.

Me~ical Alumni
Ac~ievement Awar~s
Following presentation of the Stockton
Kimball Award, Bodkin introduced the
four recipients of this year's Medical
Alumni Achievement Awards,
who were honored for "work Gotto also
above and beyond the general described potential
practice of medicine, whether
new targets for
it be teaching, research or
statin therapy.
national service."

including diabetes,
Morton A. Stenchever, osteoporosis, stroke
MD '56, was professor and and dementia. While
chair of the Department of
the drugs' efficacy in
Obstetrics and Gynecology at
the University of Washing- reducing risk for
ton's School of Medicine these conditions
from 1977 to 1996. Prior to
has not been
that, he held the same position at the University of Utah demonstrated in
from 1970 to 1977.
clinical trials,
In announcing the award, studies are
Bodkin briefly reviewed Stenbeginning, he
chever's career, explaining
that, after graduating from explained.
UB's School of Medicine, he
completed his internship and residency
training at the Columbia- Presbyterian
Medical Center in New York City. In
1962, following two years in the United
States Airforce, he joined the faculty of
Case Western Reserve University where

over the next eight years he served in a

S umm e r

2 001

l1f12ID Pbpiciu

31

�ALUMNI

number of roles prior to moving to the
University of Utah. Stenchever was unable
to receive his award in person due to an
obligation he was fulfilling in his current
capacity as professor
emeritus at the University of Washington.

Wende W. LoganYoung, MD '61, a
Buffalo native, is the
founder and director
of the Elizabeth Wende
Breast Clinic in Rochester, New York, and a
clinical professor of
diagnostic radiology
at the University of
Rochester. When it was
established in 1976, the
Elizabeth Wen de Breast
Clinic was the nation's
first freestanding mammography and breastimaging facility devoted to breast-disease
detection. Today, it is ranked
WI just want to say
as one of the nation's leading
breast-care centers and has
that when I opened my
clinic 25 years ago, I been given a grant by Blue
Cross/Blue Shield to define a
was almost laughed
Center of Excellence.
out of town. For the
"Many women from
the Buffalo area-patients
first five years, we
of mine and many doctors
didn't make any
here-have traveled to
money, but then the
Rochester to see Dr. Loganpractice took off, and
Young because she would
tell them right away whether
we did very well. And I
their mammogram was norattribute that to the
mal or not; she has really
fact that people born
helped to bring mammography
to where it is today,"
and raised in Buffalo
said Bodkin.
don't know how to
Logan-Young is also a
take no for an
past recipient of The American Cancer Society's (ACS)
answer."

3 2

lllfale Hysiciu

S umm e r

2001

Hope Award and The Distinguished Alumni Award from the University at Buffalo.
She is currently a member of the Medical
Advisory Committee for the ACS.
Following presentation of the award, Logan-Young commented:
"I just want to say that
when I opened myelinic
25 years ago, I was almost laughed out of
town. For the first five
years, we didn't make
any money, but then
the practice took off,
and we did very well.
And I attribute that to
the fact that people
born and raised in Buffalo don't know how to
take no for an answer."

Currently, she also serves as the speaker
of the House of Delegates of the Medical
Society of the State of New York. She has
served as a trustee of the State University
of New York and chief medical officer
for the New York State Department of
Health's Western Region.
Upon receipt of the Medical Alumni
Achievement Award, Nielsen stated: "I
wore two pins today. One is the UB pin
and the other is the emblem they gave me
that I'm to wear every time I represent
the AMA. I wear that for you because if
UB had not given me a chance to come to
medical school, I would have been who
knows where, and I want to thank all of
you who came before me and on
whose shoulders I stand. I think of you
always and every time I wear this, I
honor you."

Marcello Fierro, MD '66, is the chief
Nancy H. Nielsen, medical examiner for the Commonwealth
MD '76, PhD, assis- of Virginia and professor and chair of the
tant dean for student affairs at UB's Department of Legal Medicine at the
School of Medicine and Biomedical Sci- Medical College of Virginia. Only the
ences and clinical associate professor of ninth woman to have been certified by the
medicine, has been very
American Board of
active in the politics of
Pathology in forenNielson. PhD. MD '7&amp;
medicine throughout her
sic pathology, Fierro
career, Bodkin explained.
today is a Fellow of
In 2000, she was elected
the American Acadvice speaker of the Ameriemy of Forensic Scican Medical Association's
ences and serves as
policy-making House of
a consultant to the
Delegates, which, if tradiFederal Bureau of
tion holds, places her in
Investigation at the
line for the presidency of
National Crime Inthe AMA. An internist in
vestigation Center.
private practice in Buffalo,
In addition, she is
Nielsen has twice been
chair of the Forensic
elected to the AMA's
Pathology CommitCouncil on Scientific Aftee for the College of
fairs and sits on its execuAmerican Patholotive committee and Strategists and serves on
gic Planning Task Force.
the board of editors

Nancy

�Marcello Fierro. MD '66
of the American Journal of Forensic Medicine and Pathology.
Fierro has also
gained renown for inspiring the creation of
mystery novelist Patricia Cornwell's protagonist, Dr. Kay Scarpetta.
Cornwell has based the
character of Scarpetta
(the fictional chief

medical examiner for
Virginia)on her mentor
Fierro, whom she first
met in the 1980s while
working as a technical
writer in the Medical
Examiner's Office.
Cornwell has said of
Fierro, "I consider her
the best forensic pathologist in the world,
and she has been a

tremendous inspiration to me."
In accepting the Medical Alumni
Achievement Award, Fierro said, "Thank
you all very much for this award. It's hard
to accept an award for work that you
love and that you are driven to do."
Pausing, she quipped, "And I have
one other piece of information to pass
along to you: Patricia Cornwell's character is five feet tall, blonde, blue eyed
and lOS pounds!"
4D

Olmsted Ross Receives lucien Howe Medal
Iizabeth Olmsted Ross, MD '39, has received the prestigious

the award in recognition of her lifetime accomplishments in

Lucien Howe Medal for outstanding achievement in ophthal-

teaching, research and community service.

mology. The award, presented jointly by the University at

Olmsted Ross has been in private practice in Buffalo since

Buffalo School of Medicine and Biomedical Sciences and

1944. She began teaching clinical ophthalmology at UB's school

the Buffalo Ophthalmologic Society, is named in honor of

of medicine in 1955, and in 1974 was named clinical assistant

Lucien Howe, MD, who began prac-

professor, a position she still holds. She

tice in Buffalo in 1874 and founded

received a commendation for 50 years of

the Buffalo Eye and Ear Infirmary in

service at Millard Fillmore Hospital and a

1876. In addition to his private prac-

citation for service at Deaconess Hospi-

tice, Howe served as professor of

tal, where, in 1968, she was named chief

ophthalmology at the then-Univer-

of the Department of Ophthalmology and

sity of Buffalo from 1878-1909. The

chair of the residency program.

Howe medal, first presented in 1928,

Recently, Olmsted Ross was honored

was one of a number of awards he

by the Buffalo Blind Society, which

established to recognize contribu-

named their newly renovated area the

tions in ophthalmology.

Elizabeth Pierce Olmsted Educational
Center, and by the Western New York

"Past awardees of the Lucien
Howe Medal reads like a list of who's

Blind Association, which changed its

who in ophthalmology," says James

name to the Elizabeth Pierce Olmsted,

Reynolds, MD, chair of UB's Depart-

MD, Center for the Visually Impaired. A

ment of Ophthalmology. Olmsted

reception in honor of her receipt of the

Ross, who is the 23rd recipient of

Elizabeth Olmsted Ross, MD, ritflt, and James

Lucien Howe Medal was held at the

the medal, was selected to receive

Reynolds, MD, chair of ophthalmology at UB.

center on May 3, 2001.

S

11

m 111 e r

2 0 0 I

Buffale Physicin

33

�ALUMNI

Reflections on aMedical Career
Trying to practice the type of medicine UB taught me 30 years ago

For all of us, it was very
S I SA
\1 Ot.- R Spring
BY
special
indeed to see
Clinical Day dinner and
\1 CHAEI
BARO'&lt;
him again.
listened to my classmates \1 D ' 1 FCCP
Our 30th reunion
summarize their memories
allowed
us
to
rekindle
old friendships as
of UB and their careers, I felt
proud to be their colleague. What well as get to know some of our classhigher praise can I give them mates for the first time. Medical school,
except to say that I would entrust residencies and practice have been a blur
my life and care (and my family's) at times. It is a treat to have occasions
like these to reflect.
anyone in that room.
It is wonderful to practice
It was an honor to be accepted
to UB's School of Medicine. We were all medicine. We have the priviyoung and eager then, and with each day lege of seeing miracles unfold
that passed-and with every course-the in front of our eyes. In addition
enormity of our task became evident. A to witnessing people who have
lifelong commitment to study, work and healed and lived when we
excellence was what we pledged. By the thought they would die, sadly
time we reached our clinical years, the we have seen those who should
awesome responsibility of our profession have lived, pass away.
MICHAEL
had became clear to us.
I recount daily the words of
The faculty at UB were excellent and, wisdom from the internal medicine director
for our class, Dr. M. S. Megahed was the during my residency. He said, "Ladies and
best of the best. While he combined his gentlemen, you can't expect your patients
vast knowledge of neurology, neuro- to be as concerned about their health as
anatomy and internal medicine to teach you are. That's why you are the doctors."
us, he taught us far more than facts and
I suppose it is human nature, but I still
figures with his humanity, deep religious don't understand it. I struggle every day to
and family convictions, and friendship. mitigate my patients' suffering and give

• was elected to sene a sec:ond
tenn as president of the Medical Alu111nl Association on April 28,
2001, at Spring Clnical Day. Bodkin, a 1976 graduate of UB, Is a
clinical associate professor of famiiJ medicine and president
of the Hllhgate Medical Group In Wllllanmille, New YortL.
• class of 1991, becomes Yice
president of the Medical Alumni Association. Mattlmore Is a UB
clinical Instructor of pediatrics and Is on staff at Kalelda Health's

Children's Hospital and Men:, Hospital of Buffalo.

3 4

l llflil

Physicin

St~mmer

2001

them my best counsel.
If medicine has taught me anything, it
has been to keep an open mind. As knowledge expands, changes, or goes full circle,
we must adapt neither too quickly nor
too late. It is my hope that during my
career or lifetime I can begin to see and
understand the rudiments of the mindbody connection. Whether the keys will
be found in biochemistry, physiology,
neuroanatomy, or other fields
is inconsequential. It will be
our ability to harness that
great life force for wellness
first, and healing second.
At the reunion, I sought out
Philip Wels, MD '41, who initially interviewed me for a position
in the School of Medicine, and I
BARON
thanked him for the faith he
showed in me by accepting me in 1967. I
have tried to repay that faith by practicing
the type of medicine that UB taught me so
4D
many years ago.

Michael Baron is a pulmonary and critical
care physician who practices with Blue Ridge
Medical Specialists in Bristol, Tennessee.

• class of 1982, Is the new
treasurer for the association. Polack Is a UB clinical assistant
professor of ophthalmolou who Is In private practice In
WIUianmille, New YortL.

�FIRST Row, DOKALD

L.

BAROI'OE, LUDWIG R. KOUKAL,

ELI ENGEL.jONATHAK P. LEOPOLD, BERNARD SMOLENS,
MARVII'Oj. PLESKOW, LESTER E. WOLCOTT; SECOSD ROWe
AL\'1:-.1 VOLKMAN, LEO!';ARD S. DAI'OZIG, AUGUST A.
BRUNO, MARK E. HEERDT, ROBERT E. PLOSS; THIRD ROW,
ANTHOSY C. BAROI'OE. WILS0:-.1 W. SHAW. FRA!';Kj.
BOLGAS, GERARD E. SCHULTZ; FOURTH ROW, Or&gt; STAIRS,
EDWARD

:VI.

ZEHL.ER.jAY B. BELSKY, EUGE.'E V. LESLIE.

CARL R. CO!';RAD, AL.LEK

fiRST ROW: ROBERT\\". ED,fONDS.jOSEPH

T.

L.

GOLDFARB.

AQUILI. A, :\I.~RY H

BOTSFORD. GEORGE ECKH ERT; SECOS D ROW, PASQUALE A.
GRECO. PHILIP B. WELS. GEORGE GENT!';ER; THIRD ROW,
EUGENE.). HANAVAN. DANIEL.}. MCCUE, BRADLEY HULL.

fiRST ROW :

IRA

\fiLLER, ROBERT E . REISMA:-.i,jOSEPH

j . DARLAK, ROBERT B. CORRETORE. HERMA:-.1 R.
SCHOEr&gt;E, CARL N. SCHUELER; SECO;-."D ROW, PAUL
C. RONCA,JosEPH!.. Ku:-;z.jEAN C. HAAR, ERICK
REEBER, HUGH F. Oi:-.:EILL, DEK:-IIS P. IIEIMBACK,
HELENE BUERGER. ED,fO:-.ID.). GICEWICZ,jORDAr&gt;

S.

POPPER, GEORGE H. CHRIST, BERNARD II. SKLAR.
FIRST ROW, SEATED : RICHARD \\i. MuNSCHAUER, WILLIAM P. WALSH.
HAROLD.). LEVY, As;-."ABEL iRO;-."S, CHARLES D. BAUER; SECO:-.ID RO\L
EDWARD F. GuDGEL, LAwRDICE H. GoLDE:-.!, FRED S. ScHWARz.
CHARLES

A. jOY.

HARRY

E.

PETZI:-.IG, MAY:-.IARD H. MIRES. STANLEY j.

CYRAN. CARLj. ]M PELLITIER . jOSEPH R. NAPLES, HERBERT S. PIRSON,
EuGENE

:\1. \1ARKS .

\ummrr

2001

l1ffal1 Hysici11

35

�LEFT TO RIGHT: HAROLD f. GRUNERT. jEFFREY

L.

KAHLER, jAMES

COUGHLIN, CARY A. PRESANT, KENNETH V. KLEMENTOWSKI,
VIRGINIA RuBINSTEIN,jOHN RuBINSTEIN.jARED C. BARLOW, THOMAS
W. BRADLEY, CHARLES H. MICHALKO, DAVID

L.

BUCHIN, MARCELLA

f. FIERRO, ROGER W. SEIBEL, LOUISj. ANTONUCCI

fiRST ROW· TODD A. JACOBSON, THO~IAS LANE, TI!'.IOTHY P.
COOLEY,
BETTY

E.

:--,1 EREDITH HARRIS, ROBERTA SzCZUREK; SECO'&lt; D ROW:
L. BUKOWSKI. ROBERT E. KAPLA'&lt;

\'v.ELLS, STANLEY

PATRICK \\1. DIESFELD, GEORGE BANCROFT. DIASA
DA.'IELA. CASTELLANI. Ross

S.

E.

ELLIS,

SIL\ERSTEIN.

fiRST ROW: lLJAj. WEINRIEB, RICHARD A. MANCH, MOHA!'.IED
MEGAHED,jOEL H. PAULL, ROY M. 0SWAKS, HARVEY GREENBERG.
DONALD H. MARCUS: SECOND ROW: SANFORD S. DAVIDSON,
MARTIN

N.

"JANGO, SCOTT D. KIRSCH, ASKOLD D. MOSIJCZUK.

ALLEN BERLINER, NICHOLASj. CAPUA:-iA, MICHAEL B. BARON.
jERALD A. BOVINO, jONATHAN S. LEVY. jEFFREY D. fLEIGEL,

LEFT ROW BOTTO\! TO TOP· ROSYLN R. RO~IANOWSKI, PAUL C.
HOLMWOOD. LANCE A. BESNER. SANFORD H.

THOMAS G. DISESSA.

l FVY, RIC HARD WILKS:

RIGHT ROW THERESA TARTARONE URCIUOLI. STEPHEN URCIUOLI.
ANDREW P. GIACOBBE, LEO'&lt;ARD ). PORTOCARRERO, DA!'&gt;iiEL
ANDERSON, Wll.LIA!'.I

3&amp;

Summer

2001

fl. STEPHAN.

E.

�FIRST ROW SEATED. LEFT TO RIGHT: t\ILEDi

D.

CHANG. ROSAI.IND

~OI.AN SuL~I:&gt;.tAN, EussA \1. BoOKNER. JENNIFER). MoM£:&gt;~.
\II CHELLE SKRET. ·y SUSCO, KATHYLYNN PIETAK SOUTHARD, LINDA
LOR£l&gt;OZANI; SECOND ROW: KATHLEEN£. BETH IN, ADRIANA
OROZCO KELLERMEIER, LEliA KIRDANI RYAN, YVETTE M . .JOCKIN ,
jENSIFER HENKIND FERRARO, MuKESH K.jAtN,

Rou.:-~o

RODRIGUEZ, PRA!&gt;.IOD K. SHARMA. jOSEPH S. VASILE. \IARY E.
BONAFEDE. COLLEEN A. MATTIMORE; THIRD ROW: ERIC SCHUBERT,
GREGORY\\' . BRANCH, DwiGHT D. LEWIS, EDWARD PIORTOWSKI,
fiRST ROW, LEFT TO RIGHT: THOMAS K. CIESlA, WENDE

W.

YOU:-iG,

SYLVIA R. KENNEDY, j. ANTHONY BROWN; SECOND ROW : KEr-;1\ETH
E. BELL, HAROLD BRODY, RICHARD C. HATCH, RONALD

H.

\IATTHEWj. PHILUPS , ASTHONYR. RICOTTONE , PHlUPj. RADOS,
jOHN P.jOHN. MARKj. :\1ANCUSO,jOSEPH P. BONAFEDE.

USIAK,

EuGENE A. CI~IINO, :'viiCHAEL MADIANOS, ROBERT \1. \10RA!';,
GERALD

v.

ScHWARTZ, ALFRED \lEssoR E. HE. ·RY F. GoLLER,

MICHAEL E. COHE .. , HOWARD C. WI LINSKY. FREDERICKS.
CIESlAK. SEY~!OURj. LIBERMAN.
THE REUNION PHOTOGRAPH FOR THE Cuss OF 1996 WILL BE
PUBLISHED IS THE AUTUMK ISSUE OF BUFFALO PH}'S/CHS.

Gifts committed to the School by those celebrating reunions
this spring totaled over $170,000, the largest class fund drive
ever. On behalf of the UB School of Medicine and Biomedical
Sciences, I extend a very sincere thank you to the class chairs
and their classmates who responded. We are fortunate to have
your support and greatly appreciate your generosity.

-Lyn Corder, Director of Development
FIRST ROW. LEFT TO RIGHT: SUSAN H. BARDE, LINDA

\1.

WILD,

KARE. ·A. Gu.scow, KATHLEEN C. ACKERMA!';: SECOND ROW:
STEPHAN LE\ ITT, Do. 'ALD GEORGE, SHINY. l.IONG, MICHAELA.
SMITH, CHRISTOPHER). BARDE. DANIEL R. WILD, jOHN.). BOOK!.',
PATRICK R. HAYES. CHRISTOPHER F. BRA.'DY, GREGG BROfFMA.',
ANDREW

\1.

GAGE, PAUL P. ScHWACH. LAZLO TOMASCHEK. GRANT

GOLDEN.

Summrr

2001

llffall nysicial

37

�0

E

V

E

L

0

P

M

E

N

T

E

W

S

Gifts of Anwork Beautif Our School
By Li nda J . Cor de r , Ph0, CFRE
we
tend to focus on the larger monetary ones of stocks,
bonds, charitable unitrusts and estate plans because they
have the power to transform the school.
As vital as these larger gifts are, however, we also
deeply value other contributions; for example, the
many volunteers who give of their time. Think about
the Dean's Advisory Council, Campaign Steering Committee and National Advisory Group, or the Medical
Alumni Association Board, Medical Student Parents'
Council and newly formed Medical Faculty Emeritus
Group, all of which add to the richness of the fabric
that comprises our UB Family. Then, there are the class
reunion chairs, alumni who return to talk with students
about their specialties, alumni lecturers and the volunteer faculty, a most important group throughout the
institution's history.
This past year, a group of students became interested in
AT PRESENT, WE ARE COMPILING
beautifying their school and put
A LIST OF ALUMNI ARTISTS AND
out a call to alumni for gifts of
FRIENDS OF THE SCHOOL WHO
artwork that could be displayed in
WOULD LIKE TO MOUNT EXHIBITS
classrooms, study areas and the
OF THEIR WORK OR CONTRIBUTE
standardized patient offices, to
TO THE SCHOOL'S PERMANENT
name a few venues.
COLLECTION. PLEASE LET US KNOW
As a result, the school is
IF YOU WOULD LIKE TO BE ADDED
now beautified with works of art
TO THIS LIST.
such as those presented by one of
our alumni who works for the

38

laffal1 Physiciaa

Summer

2001

Journal of the American Medical Association and who
sent two prints from a show of the journal's cover art.
Also, in May of this year, with the help of one of our
volunteers, students hung an exhibition of photographs
taken by an alumnus. Another alumnus
donated a dozen prints on the history of
medicine that formerly hung in his office,
all of which will be exhibited in a location
where they may inspire students.
Many others have contributed posters
and prints, including Evolution (see below)
and the Herd of Buffalo, as well as depictions of plants and flowers.
In addition to gifts from alumni, the school has
received from the Association of American Medical
Colleges a set of five signed prints by Jim Dine (see back
cover) . We also have a study of ]ames Scott, Himalayan
Survivor signed by both Dr. Scott and the artist,
Martin Howard Boscott, a gift from philanthropists
in Melbourne, Australia.
At present, we are compiling a list of alumni artists
and friends of the school who would like to mount
exhibits of their work or contribute to the school's
permanent collection. Please let us know if you would
like to be added to this list.
4D

Linda (Lyn) Corder is associate dean and director of
development. She may be reached by phone, toll free, at
1-877-826-3246, or by e-mail, at ljcorder@buffalo. edu.

�Dear Fellow Alumni,
Sl'

.. ;S; 0 ·~in; ~"p11e11ed tc •ne on my way to a recent alumni board meeting. Patricia

Duffner, MD '72, told me she was not going to be able to serve as incoming president for our
Medical Alumni Association. She had a couple of unexpected situations come up that were going
to require a great deal of her time.
After discussing this with Bertram Partin, MD, '53, former assistant dean for
alumni affairs, I decided to offer my services to the board as president for another
year. As you all know, I felt very privileged to have served in this role for the past
year. I feel I already "know the ropes" and so will be able to help the school even more
in my second term in office. As president of our alumni association, I will work alongside Colleen Mattimore, MD '91, and Stephen Pollack, MD '82, who were elected vice
president and treasurer, respectively, for the coming year.
In the months ahead, I will keep you apprised of changes in the Medical Alumni Office in
follow-up to the restructuring plans recently announced for the office, as discussed on the inside front cover. Since these changes were announced as this issue of Buffalo Physician was
going to press, I'm unable to provide further details at this time. However, I will do my best
to give you as complete an update as possible in the fall issue of the magazine.
In other news, a major change in the bylaws of the Medical Alumni Association was approved
at the annual meeting held during this past April's Spring Clinical Day and Reunion Weekend. We
voted to expand our membership to include emeritus professors, fellows and residents of our
graduate medical education programs. These changes will enable us to continue on our course of
motivating more people to become interested and involved in "giving back" to our school. Anyone
who feels that they might fit into one of these groups and would like information about joining our
association, is invited to contact

ancy Druar in the Medical Alumni Office, at (7 16 ) 829-2778.

Finally, I would be personally remiss if I did not mention our continuing effort to expand the
number of alumni who hold lifetime memberships in our association. So, again, please consider
supporting our school by becoming a lifetime member of the UB Medical Alumni Association.
Thank you for the opportunity to serve another year.

jOHN

J.

BODKIN II , MD

President, Medical Alumni Association

St~mmer

2001

Buffalo

Physician

3 9

�CLASSNOTES

Charles J McAllister, MD,
'73, writes: "Since July

2000, I have been in the
position of chief medical
officer of DaVita, the
second-largest dialysis
company in the world.
We have over 430 dialysis units in 34 states. I
finally ended clinical
practice last year. Very
good news is that Diane
and I are to be first- time
grandparents this year.
I maintain offices in Los
Angeles, CA, and in New
Port Richey, FL."
E-mail address is:
HKidneydoc@cs.com.
Richard J. Goldberg, MD '74,

writes: "I am currently
professor of psychiatry
and medicine at Brown
University and psychiatrist-in-chief at Rhode
Island Hospital and
The Miriam Hospital in
Providence. I graduated
from the Harvard School
of Public Health with a
masters of science in
Health Care Administration in June 2001."

1980s
Michele J. Armenia, MD '86,

Barrington, IL, gynecology, writes: "My husband, Robert Aki, MD,
and I have three children: Maria, age three,
Matthew, age two, and
Laura, eight months."

4 0

I u If a I a

Amherst, NY, writes: "I
completed a lung transplant fellowship in Pittsburgh, PA, in 1991 and
currently work in pulmonary and critical care
medicine. I am married
to James Houck, MD."
E-mail address is:
lcampbell@kaleidahealth.org.

as anyone and writes
about them with passion
and compassion. This
fine, wrenching novel
chronicles the
addiction of a physician
with sensitivity and
fearlessness. Dr. Joseph
Molea has crafted a wellwritten, important, intensely engaging novel."

Karin E. Choy, MD '86,

Sean T. O'Brien, MD '86,

writes: "Turning 40 has
been anything but uneventful! I've finally returned to New York
from Connecticut and
have taken the position
of medical director for
Clinical Associates for
Rehabilitation and
Evaluations, Inc. I also
found time to get remarried (to a non-medical
UB alum) in April, and
we're dividing our time
between homes in the
city and Long Island.
Can't wait to see what's
next!" E-mail address is:
kcmd@worldnet.att.net.

Alpharetta, GA,
interventional radiology,
writes: "My
wife, Sandy,
and I have two
children: Kasey,
age seven, and
Jake, age four."
E-mail address:
styob@aol.com.

Lucy A. Campbell, MD '86,

1970s

Katrina Guest, MD '86,

Waukee, IA, pulmonary
medicine, writes: "My
husband, Andrew, and
I have two children:
Adam, ten, and Nathan
six." E-mail address is:
kaguest@home.com.
Joseph Molea, MD '86, will

publish his first novel,

Duck
Blood
Soup, this
summer.
Molea
trained as

Physic i a a

Summer

a general surgeon, has a
subspecialty in addiction
medicine and practices
administrative medicine
as the executive director
of Health Care Connection of Tampa, Inc., a
chemical-dependency
rehabilitation facility
specializing in the treatment of impaired
professionals.
He lives in St. Petersburg, FL, with his wife,
Heidi, a school teacher,
and their twin 16month-old daughters,
Sophia and Abbegail,
whom they adopted
from Cen tral Asia last
year. Heidi is expecting their third child
due this fall.
Duck Blood Soup is the
first-person account of
one physician's struggle
to become a surgeon
while losing his grip on
reality through Demerol

2 0 0 1

addiction. Senior surgical resident Rocky Van
Slyke is young, single,
living in Philadelphia,
at the brink of a brilliant
professional career.
He should be happy.
He's not.
Molea skillfully dovetails Rocky's memories
into the present-day
odyssey of the young
physician's own substance abuse, and,
through the character of
Vincent G. Buddy, the
hospital attorney, demonstrates, with alarming
accuracy, how the culture of abuse is passed
from one generation of
physicians to the next.
Acclaimed author,
Dr. Michael Palmer
wrote of this work:
"Duck Blood Soup is a
powerful, haunting
story. Joseph Molea
knows the inner workings of addiction as well

Deborah Richter,
MD '86, Montpe-

Sandy and Sean
O'Brien

lier, VT, family
practice, writes: "My
husband, Terry Doran,
and I have two children:
Justin, age 12, and
Patrick, age 11. My
favorite memory of
medical school were
the parties at Wally
Straus' house."
Roslyn R. Romanowski, MD
'86, E. Amherst, NY,

hematology/oncology,
writes; "My husband,
Robert Campo, and I
have one son, Richard,
age three." E-mail
address is: rromanow
@alum.mit.edu.
Alan M. Stein, MD '86,

Hooksett, NH, family
practice, writes: "My
wife, Susan Kunkel, and

�I have three children:
Sarah, age 15, Kevin, age
13, and Jimmy, age 10.
Theresa Tartarone, MD '86,
and Stephen Urciuoli,
MD'86, Westport, CT,
internal medicine, write:
"We have three children:
Stephanie, Carmine
and Anna."
Valerie E. Whiteman, MD '86,

Hockessin, DE,
obstetrics/gynecology,
completed a MFM Fellowship at the University
of lllinois at Chicago in
1990-1992. E-mail
address is: drvwhite
@home.com.
Kathleen Grisanti Lillis, MD
'87, has received the

2001 Catherine McAuley
Distinguished Alumna
Award from the
Alumnae Association of
Mount Mercy Academy
in Buffalo, NY.
The award is presented to an alumna of
the academy "who has
distinguished herself
as a woman of faith,
knowledge, integrity and
compassion; a
woman
whose accomplishments in
all areas

of her life-her family,
her community, her
career-reflect the legacy
and mission of
Catherine McAuley, the
foundress of the Sisters
of Mercy.
Lillis is chief of the
Division of Emergency
Medicine and medical
director of the Emergency Department at
Children's Hospital
of Buffalo.
According to Mount
Mercy Academy, she has
"dedicated her life to enriching the health, safety
and well being of infants
and children.
1n addition to managing an emergency
department that is one
of the best pediatric
facilities in the country,
Kathleen is also the
volunteer director of
Mercy Flight. She is on
call for the helicopter
team 24 hours a day,
fielding calls and directing care, all for the
welfare of children.
As a distinguished
alumna, Dr. Lillis's life
models that of Catherine
McAuley in her persistence to improve the
quality of life for children, in leading by example and in believing
that one life can make
a difference."

Vasile Chief of Psychiatry at faleahh Care

1990s
RohitBakshi, MD '91, neurology and neuroimaging,
writes: " My wife, Lori,
and I are
thrilled to
announce
the arrival
of our
first child,
Adam. He
has added much excitement and joy to our
lives. He has been welcomed enthusiastically
and lovingly by his four
beaming grandparents
who also live in the Buf-

falo area, including Dr.
George Baeumler, MD
'59, and Dr. Suraj Bakshi,
associate professor of
nuclear medicine at UB."

ite medical school
memories include
friends, Dermatones,
yearbook staff." E-mail
address is: gwmbranch
@aol.com.

Kathleen 8ethin, MD '91,

St. Louis, MO, pediatrics, writes: "I am currently working at St.
Louis Hospital in Missouri. E-mail address is:
beth in_k@kids. wustl.ed u.

Paul A. Brill, MD '91,

Anderson, SC, neurology, writes: "My wife,
Sandy, and I have a son,
Andrew, age nine."
E-mail address is:
pabrill@viafamily.com.

Gregory Branch, MD '91,

Baltimore, MD, internal
medicine, "I have a son,
Byron, age 11. My favor-

assnotes
Sllmme r

200 1

Aileen Chang, MD '91, Stony

Brook, Y, gastroenterology, internal medicine,
writes: "My favorite
memories of medical
school include orientation week." E-mail address is: achang@pol.net.

Buff a l o Phy sic i a a

4 1

�CLASSNOTES

Robert C. Dukarm, MD '91,

neonatology, Buffalo,
NY, writes: "My wife,
Carolyn Dukarm '89,
and I have two sons:
Ryan, age four, and
Matthew, age two."

have three children:
Steven, Donovan and
Elaina. My favorite
memory of medical
school was playing
pool at Chevy's Bar
and Grill."

John Gelinas, Jr, MD '91,

Ingrid C. Helmer, MD '91,

Redding, CT, child and
adolescent psychiatry,
writes: "My wife, Carole,
and I have three children: Andrew, jackson
and Emuly. My favorite
memories of medical
school are times with my
friends. UB was a great
experience!" E-mail
address is: jgjrchbg
@gateway. net.

Lunenburg, MA,
pediatrics, writes: "My
husband and I have two
children: Natalie and
Katherine."

Toby D. Goldsmith, MD '91,

Gainesville, FL, psychiatry, writes: "We have a
new little boy, Reid
Mitchell Shapira, born
in September of2000."
E-mail address is:
goldsmith@pol.net.
Ronald Hale, MD '91,

Victor, Y, public health
and general preventive
medicine, writes; "My
wife, Cynthia, and I have
two children: Madeline
and Benjamin. Among
many other things, I am
still under active duty
with the Air Force."
E-mail address is:
erhale@sajx.rr.com.
Steven P. Harris, MD '91,

Gibsonia, PA, pulmonary, critical care, writes:
"My wife, jane, and I

4 2

I u If a I o

La jolla, CA, ophthalmology, writes: "We
have a son, Erik Willem.
My favorite memory of
medical school was the
Follies." E-mail address
is: yvette@jockin.com.

Tualatin, OR, anesthesiology, writes: "My favorite memories of medical
school include studying
in the study hall with
my friends and then
wandering around campus to find different
places to study when it
got too crazy in the
study hall-and Buffalo
wings!" E-mail address
is: kubota@teleport.com.

Physician

Summer

Bethesda, MD, pediatric
endocrinology, writes:
"My husband, Eric
Feyer, and I have a
daughter, Elyssa, and a
new one due in August
of 2001." E-mail address
is: dmerke@nih.gov.

Stephen Lipsky, MD '91,

Susan Y. Kubota, MD '91,

Amherst, NY, internal
medicine, "My wife,
Erica, and I have four
children, Danitra,
Diandrea, Delmarie and
Dwight. My favorite
memory: 'Rubbish,' or
brownies." E-mail address is: dlera@aol.com.

Deborah Merke, MD '91,

'91, Westford, MA,

physical medicine and
rehabilitation, writes:
"My wife, Kathleen,
and I have two
children: Marc and
Elena. My favorite
memories of medical
school: friendships,
colleagues pulling together to help each other
through difficult times;
first time on the wards;
acceptance and graduation." E-mail address is:
pliguori@pol.net.

Yvette Jockin, MD '91,

Dwight Lewis, MD '91 ,

Paul Anthony Liguori, MD

Dunwoody, GA, pediatric ophthalmology,
writes: "I completed a
pediatric ophthalmology
fellowship in 1996 at
Indiana University. My
wife, Karen, and I have
two children: Harrison
and Alexandra." E-mail
address is: thelipskys
@media.one.net.

'91, Loganville, GA,

psychiatry, writes:
"I work for a community mentalhealth organization
at a crisis stabilization

inpatient unit." E-mail
address is: cbmorgan
@medscape.com
RichardS. Musialowski Jr.,
MD '91, Rock Hill, SC,

2 0 0 I

rics, writes: "My wife,
Kathleen, and I have two
children: Connor james
and Ryan Elizabeth. I am
currently on the hospital
staff at Children's Hospital of Philadelphia."

E-mai

Forest Hills, NY, obstetrics/gynecology, writes:
"My favorite memories
are brownies, anatomy
lab (our group was very
funny) and finishing!"
E-mail address is:
jabram5453@aol.com.

Keene, NH, pediatrics,
writes: "My husband,
Dean, and I have three
children: Anna, Maxwell and jonathan."
E-mail address is: janmcgonagle@hitchcock.org.

Kevin C. Osterhoudt, MD
'91, Radnor, PA, pediat-

Carol Bradley Morgan, MD

Susan J. Littler, MD '91,

Jan McGonagle, MD '91,

help me out when I had
troubles with my
classes-that they stuck
with me. That support
meant much for me."
E-mail address is:
atn0623@aol.com.

cardiology, writes: "My
favorite memory of
medical school was Friday afternoon anatomy
lab that continued on to
become chicken wings
and darts at a local
establishment." E-mail
address is: musialor
@rjsonline. net.
Anthony T. Ng, MD '91,

Brooklyn, NY, psychiatry, writes: "My favorite
memory of medical
school includes having
really good friends to

Terrence S. Peppy, MD '91,

Orlando, FL, obstetrics/
gynecology, writes: "My
wife, Renee, and I have
three children: Christopher, Stephen and
Nicholas. My favorite
medical school memories include classmates
and rotations."
Edward S. Piotrowski, MD
'91, Orchard Park, NY,

general surgery/trauma/
burns/laparoscopy,
writes: "I am a member
of the American Burn
Association. My wife,
judith, and I have two
children: Elizabeth and
Derek. My favorite
CONTINUED ON PAGE 44

�Lloyd A. Clarke,
MD'38
Clinical associate professor emeritus in psychiatry

Abraham%.
Freudenhelm,
MD'38

Paul Kendrick
McKissock, MD
'SG
Renowned plastic surgeon

.Jerome.J.
Maurlz:l, MD 'S2
Founder of Occupational
Health Services

Summer

2 0 0 I

lllfal•

nrsicia•

43

�CLASSNOTES

I

wife, Donna, and I have
two children: Joey and
Christopher. My favorite
medical school memory:
Thursday night Simpsons
and get togethers."
E-mail address is:
joewmd@hotmail.com.

CONTINUED FROM PACE 42

Cook at Strong Memorial

medical school memories include: ( l) The 'P'
dissection group in gross
anatomy; and (2) When
my partner in secondyear clinical asked an
elderly patient, "Do
you have a history of
subacute bacterial
endocarditis?"

Residents
Arif R. Alam, MD, has been

Phil Rados, MD '91, Buffalo,

NY, writes: "My wife,
Genevieve, and I have a
son, Francis ( Frano ),
born on january 31,
2001." E-mail address is:
amalavinica@hotmail.com.

Stephanie Han, MD '96,

Susan, and I have two
children: )yoti and
Ravi." E-mail address is:
pramodksharma@aol.com.

New York, NY, radiation
oncology, writes: "I will
join the faculty practice
at ew York University
Medical Center in July."
E-mail address is:
stephanie.han@yale.edu.

Michelle (Skretny) Susco,
MD '91, Clifton, VA, pedi-

Eileen Reilly, MD '91,

Buffalo, NY, family practice, writes: "I am married to Ray
Gomez. My favorite medical
school memories
include finishing
the first year and
planning a trip
Ray Gomez and
across the coutry."
Eileen Reilly

Vicki L. Seidenberg, MD '91,

New York, Y, physical
medicine and rehabilitation, writes: "My
husband, Mark, and I
have two children: early
Brooke and Leah Nicole.
My favorite memorygraduating!"
Pramod K. Sharma, MD '91,

Ann Arbor, MI, otolaryngology/head and
neck surgery, writes:
"I am currently on staff
at the University of
Michigan. My wife,

4 4

la lf al t

atrics, writes: "Among
other things, I recently
finished a program for
'Physicians Leading
Change' at Georgetown
University Medical Center." E-mail address is:
jmcsusco@erols.com.

Rudolph Joseph Schrot, MD
'96, Sacramento, CA,

Beth MacDonald, MD '96,

Portland, OR, internal
medicine, writes: "One
of my favorite memories
of medical school is
Karin Selva's cabin
party." E-mail address
is: sqrmf@aol.com.

Joseph A. Zarzour, MD '91,

Wichita Falls, TX, pediatric ophthalmology.
"My favorite medical
school memory: The
feeling of relief after a
block of exams!"

Paul S. Matz, MD '96,

Pawtucket, RI, writes:
"My primary specialty is
general academic pediatrics." E-mail address is:
psm9@cornell.edu.

Cindy (Repicci) Romanowski, MD '94, and Marcus

John S. Pulvino, MD '96,

Romanowski, MD '93,

Old Orchard Beach, ME,
obstetrics/gynecology.
E-mail address is:
jpulvino@mmicservices.com.

write: "We welcomed
our second child, Rachel,
on April13, 2001.
She joins Marcus Jr,
age three."

Phy si c i aa

children: Katherine,
Michelle and Rachel.
My favorite memorygraduation!" E-mail
address is: kmrobillard
@aol.com.

Kristen Schenk Robillard,

neurosurgery, writes:
"I remember drawing
inspiration from my colleagues during Intro to
Clinical MedicineClara K., Eileen K., Brad
D.-for their enthusiasm and discipline."
E-mail address
is: rudolph.schrot
@ucdmc.ucdavis.edu.
Karen Sneii-Garus, MD '96,

Williamsville, NY,
obstetrics/gynecology,
writes: "My husband and
I have two children:
Mitchell, age four, and
Kyle, almost two. My
favorite memories:
anatomy, snow, late
nights in the CT room at
ECMC, the Law library."

MD '96, Orchard Park,

NY, family medicine,
writes: "My husband,
Paul, and I have three

Summer

2 0 0 I

Joseph C. Wittmann, Jr.,
MD '96, Amherst, NY,

pediatrics, writes: "My

appointed to the
Division of Blood and
Marrow Transplantation
in the Department of
Medicine at Roswell
Park Cancer
Institute
(RPCI). He
has also been
named an assistant professor of medicine at University at
Buffalo's School of Medicine and Biomedical Sciences. Alam joints RPCI
and UB from
City of Hope National
Medical Center in
Duarte, California, where
he completed a clinical
fellowship in bone marrow transplantation. He
earned his medical degree from Dow Medical
College, Karachi, Pakistan, in 1991, and completed residency training
in medicine at UB
in 1996.

A nutnber flf Clasnotes
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the autumn 20011aue.

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- Frank Ste/ars/&lt;.j, stroke rehab patient, Harris Hill H.C.F.

Why do our patients have better rehab resutts compared to the national average? Maybe it's our staff
''They knew exactly how far to push me:' says Frank Stelarski.' 'But they also encouraged me every little
step of the way. When you've been through what I have, that really means a
lot.'' To leam more about the nationally recognized McGuire Rehabilitation

11IE

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Centers, call 1-888-POSTACUTE or visit www.mcguire-group.com.

Recognized for excellence in quality care.
AUTUMN VIEW

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ARTIST jiM DINE's
PRINTS ON DISPLAY

Heart is one of five prints
by Jim Dine , a well - known
modern artist. Astra USA
commissioned the prints
and made an initial gift of
several sets to the Associ ation of American Medical
Colleges (AAMC) for dis tribution to its nonproft
member institutions. In
1997 , the AAMC gave set
81 / 400 to the University
at Buffalo 's School of
Medicine and Biomedical
Sciences. The prints hang
on the second floor of the
Biomedical Education
Building on UB ' s South
Campus. Recently , Heart
graced the cover of the
brochure for the school's
Spring Clinical Day , the
theme of which was "The
Healthy Heart. "

liP 0001

02

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                    <text>�AssOCIATE \ ICE PRESIDE"T FOR
UN I\ ERSITY Co~n! UNICATIONS
Dr. C arole Smit/1 Pe tro

DIRECTOR OF PERIODICALS
S u e Wu e tcl1 e r

EDITOR

Dear Alumni and Friends,

S t ephanie A. U nge r

ART DIRECTOR &amp; OESIG"
A lan j. Keg le r

OVEMBER, I ATTENDED THE AN UAL MEETING of the Association of American

DESIGNER
Da v id f. Riley

Medical Colleges (AAMC) in Washington, DC, along with other individuals representing
our school. An important reason for attending meetings such as this is that they provide a

0ESIG'I ASSISTANT
Ka re n Lie/m e r

national perspective on challenges faced by medical schools. This, in turn, enables us to
understand that many of the day-to-day issues we deal with at UB are not unique but are
instead part of larger trends and patterns.
For example, we learned that, like UB, most medical schools are having difficulty placing their third- and four-year students in clinical teaching sites because faculty are increasingly situated in outpatient environments. In these environments it is difficult for faculty
to take time to teach because of their patient load and paperwork.
We also learned that about one-third of all medical schools are
experiencing financial difficulties due in large part to the debt being
incurred by their hospitals. While we do not have a university hospital
and our school is not in debt, we do have pressing issues related to the
dispersed nature of our school and its affiliated clinical sites.
If we are to address these issues, it is important that we communicate
with one another in an open and consistent way. This fall, therefore,
the school's senior associate deans and l began hosting a series of Town
Hall meetings at our affiliated hospitals and on campus. These meetings,
attended by faculty, students, residents and staff, have spurred productive discussions
about a wide range of issues. In order to share the content of these discussions with as many
people as possible, we have prepared notes from each meeting and distributed them on a
listserve. If you would like to be included on this listserve-which distributes other schoolrelated announcements, as well-please send your e-mail address to Mary Glenn, director
of constituency relations in the Office of Alumni Affairs, at glenn@acsu.buffalo.edu.
Another challenge schools are facing is the introduction of new curricula. At the AAMC

CONTRIBUTING WRITER
Lo is Ba k e r

PRODUCTION CooRDINATOR
Cy nthia T o dd - Fli ck

UN I\ ERSITY AT BuFFALO
SCHOOL OF \1EDICINE AI'D
BIOMED ICAL SCIENCES
Dr. Mi chael B e rnard i n o , D~oll

EDITORIAL BOARD
Dr. f o /w Bodk i n
Dr. M artin Brech e r
Dr. Har old Brody
Dr. Linda j. C orde r
04
ja son H offmann , C lass of 20
Dr. jam es Kan ski
Dr. Eli z ab e th Olm s t ed
Dr. j a m es R . Ol so n
Dr. S t eph e n Spauldin g
Dr. Bradley T . T ruax
Dr. Franklin Z eplowit z

TEACHING HOSPITALS
Erie Co unty M ed ica l Ce nt er
Ros well Pa rk Ca ncer In st itut e
\'et eran s Affairs Wes tem
New }'~r k Hea lth care Sys tem
K :\ll:ID," H t:-\IIH:

T il e B uffa lo Ge nera l H ospital . 1
Tir e Clril d ren 's Hospit al of Buffll 0
M ill ard Fillm ore Ga t es Hospital . 1
Millard Fillm o re S ubu rban Hosprta

meeting we learned that our peer institutions are finding that it takes anywhere from four
to eleven years from the inception of a new curriculum to the time it is solidly in place and
well adapted to the school's needs and educational goals. As you know, we introduced a new
curriculum at our school this past fall. One thing I assure everyone when talking about this
milestone achievement is that the new curriculum is a "work in progress" and one that
will be evaluated and improved with as much input as possible from everyone involved.
Finally, I would like to announce that according to numbers provided by the AAMC, our

CArttotn H f.-tt1H S1srr\f:

M ercy Healtlr Sys tem
S isters of Clra rit y Hospital
N iaga ra Falls Me m orial
M edi cal Ce nt er

® UNIYEISITY IT IUFFILI.
THE STATE UNIYEISITY If lEW Till

school 's basic science faculty produce above the 90 percentile in revenues, per individual,
when compared with other medical schools in the United States (specifically, $300,000/
faculty). What this tells us is these faculty are bringing in large amounts of grant dollars in
an exceedingly competitive environment and that their work is of the highest quality.
This is something I think we should all be very proud of, and it is a strength we will do
our best to maintain and build upon in the future.

J.

R,

(LA~; ....

-c)

~~- BERNARDINO , MD. MBA

Letters to the Editor
Buffalo Plly;rcum "published quarterlY
h)' the Um,·ersitv at Buffalo School nf
~1cdicine and Biomedical

S(ICO(CS Ill

cooperation with the Office of
(.ommunicatiOns.

Letter&gt; to the Editor arc wckoille
.md can be sent c/o IJ11(jalo Plr)'srcu"'·
330 Crofts Hall, Univ~r"t' at Bufl,,to,
Buffalo, NY t 4260; or vi,J e-nMil to
bp-notcs~• bufti1lo.edu.

.
·dit ,Jll
The &gt;taft re&gt;en·c; the nght to&lt;
submissions for length and darity.

Dean, School of Medicine and Biomedical Sciences
Vice Presiden t for H ea l t l1 Affairs
University at Bu

ffalo
}vrk

The State Uui~'Ct'Sity ofNeW

�V

0

L U M E

36,

Features

2

10

18

Healing in the Aftermath
A report on three UB psychiatrists' work
at Ground Zero and environs
BY

S. A.

UNGER

First Impressions, Lasting Memories
Buffalo Physician readers write about
September 11, 2001

One Woman's Global Concern
Bess Miller, MD '77, a leader in efforts
to prevent and treat AIDS and TB worldwide
BY BETSY SAWYER

COVER

Convocation

26

Christiane
Northrup, MD,
delivers the
inaugural
Lawrence and
a ncy Golden
Lectu re

EdwardS. Cheslow, MD '81, above, contributes to "First Impressions, Lasting
Memories" about September 11, 2001. starting on page 10.

Litchman,
Class of 1960,
ho nored as
Distinguished
Medical
Alumnus

41 Messages from
this year's
reun ion chairs

alumn i

31 Lawrence
jacobs, MD,
and Gloria
Roblin, PhD,
remem bered

grant to
fund study of
lin k between
periodo ntal
d isease and
hea rt d isease

34 Program
project gra nt to
develop vaccine
fo r ear and
respiratory tract
in fections

PHOTO

OF ANTHONY

tori um to the
Hospitalthe Third-Year
Experience,
by Svetlana
Bli tshteyn,
Class of 2002

No

BY

00UC

LEVERE

other alumni

46 Past Forward,
a unique
perspective
on the Class
of 1976

�BY S.A.

Areport on three UB
psychiatrists' work at
Ground Zero and its
environs

u

GER

N THE LONG HOURS FOLLOWING THE ATTACK on the World

Trade Center on September 11, 2001, many healthcare professionals trained to respond to disasters found themselves in limbo as
they awaited a tidal wave of patients that instead arrived at their
doors as a wayward trickle.
As the days passed and even the trickle dissipated, it became clear
that the definition of a worst-case cenario was being reconstructed
in this environment of limited activity. Instead of physicians equipped to deal with the most devastating of physical traumas, what
was needed were physicians equipped to treat psychic trauma on a scale
previously unimaginable in our country.
One physician well prepared to galvanize a response to this hastily
redefined disaster wasAnthonyT. g, MD '91, who at the time of the attack
was treasurer and vice president of operations for Disaster Psychiatry
Outreach (DPO), an organization for which he is now medical director.
Headquartered in ew York City, DPO comprises volunteer psychiatrists
committed to providing on-site disaster mental health services, as well as
to producing educational programs, research data and policy statements
in support of this mission.

�••••••••• ,. c ••

�e
p

The photographs in this

a.::»

article that depict me-

...

morials erected on the

E5

e

1 I

streets of New York City
after the September 11
attack on the World
Trade Center were taken
by Bruce Jackson, SUNY
Distinguished Professor

and Samuel P. Capen Professor of
American Culture at the University
at Buffalo. Sixty of Jackson's photographs-documenting the commemorative candles, photos, flyers,
notes, toys and flowers left in New
York City's Union Square and
Sheridan Square, at St. Vincent's
Hospital and on the streets of lower
Manhattan-were exhibited October

16--22, 2001, in UB's Center for
the Arts.
Jackson notes that many of the
items displayed originally posed
questions as to the whereabouts of
thousands of individuals lost in the
attack. By September 22, when he
took the photographs, however,
they had become memorials.
"Every place you go in lower
Manhattan," he says, "you see
sheets of paper taped to walls,
fences, kiosks and lampposts.
They're all about people who
are missing.
"Most of the city's firehouses
and parks have shrines-things
people made or left to try and say
something that could not be sail!
in words."

Buffalo Physician would like

to thank Professor Jackson for
his generosity in allowing us to
include his photographs in this
article. We would also like to thank
Patricia Donovan, senior editor in
UB's News Services, for providing
the above information about
Jackson's exhibit.
-S. A.

UNGER

AST SUMMER, NG HAD CALLED his former
teacher Cynthia Pristach, MD '83, associate
professor of clinical psychiatry in the University at Buffalo's School of Medicine and
Biomedical Sciences, and asked if she would
be interested in not only joining DPO, but
also in expanding its membership in Western ew York.

Pristach joined the organization and recruited a number of her UB colleagues, including Linda Pessar, MD, associate professor of clinical psychiatry, and
Helen Aronoff, MD '92, assistant
professor of clinical psychiatry in the Division of
Child and Adolescent Psychiatry.
Two weeks after the attack on the World Trade
Center, g was again on the phone to Pristach,
asking if she and other members of DPO in Buffalo would be willing to come to ew York City to
work at two sites: the Family Assistance Center and
Ground Zero.
g said he contacted Pristach because he was
confident his former medical school professors
would be up to the task. ''I'm biased because I know
both Cindy [Pristach] and Linda [Pessar]," Ng
admits, "but I also knew they would be very helpful
for two reasons: First, they are very experienced,
and second, there were a lot of Buffalo folks down
here that week, both with the ational Guard and
as firefighters, and I thought their having that
connection would help us. Too, I knew Linda had
previous experience working with firefighters,
and that was a nice addition because they are a
very tough group to get close to."
On September 27, 2001, two days after

she had the courage she would need. They assuaged
many of these feelings by talking with one another
and by confronting what Pessar calls "the imagined
chaos of this time."
The evening before they departed, which was the
eve of Yom Kippur, Pessar and Aronoff went to
services together. "We each would have done this
anyway," says Pessar, "but I felt like we were preparing to enter another psychic space, and when
we ended our final shift in ew York City that
following Saturday, we accompanied Cindy to
mass at St. Patrick's Cathedral.
"So, it occurred to me that, in this time of crisis,
we were mobilizing around the values of the
important institutions in our lives-that we were
bounded by religious, patriotic and vocational
values," adds Pessar.
Upon their arrival at La Guardia Airport, Pessar
and Aronoff, both New York City natives, immediately noticed a dramatic change in the city. "Everything was spooky," says Pessar. "The airport was
empty when we arrived, and the taxi dispatcher in
Manhattan thanked us for coming! Everything was
sort of tumbled about."
That same evening, Pristach accompanied g to
Ground Zero, where he taught her the protocol
for intervention so that she could in turn teach it
to Pessar and Aronoff in the days that followed.
Pessar and Aronoff did not go directly to Ground
Zero, but instead began a 4 p.m. to midnight shift
at the Family Assistance Center, located in the
cavernous Pier 94 on the Hudson River, which
housed a wide array of centralized services for
families and survivors.

g

called, Pristach, Pessar and Aronoff boarded a
plane to New York City.
In recalling their decision to help, all three
psychiatrists say that while they were not ambivalent about going, each did experience some anxiety
prior to departing and even questioned whether

THE FACES OF TRAGEDY
At the Family Assistance Center, Pessar and Aronoff
began work at a booth next to another sponsored
by the ew York City Department of Mental
Health. Thousands of people milled about,

�availing themselves of services provided by such almost like what you would see in a painting."
Some people needed counseling and referral,
organizations as the Red Cross, Salvation Army,
Social Security Administration, and Department of while others needed simple advice or an opportuVeterans Affairs, as well as the mayor's office and nity to vent anger, frustration, grief and fear.
the city's police and fire departments. Also on site Counseling sessions took place anywhere the psywere groups prepared to provide assistance with chiatrists encountered need, and the need they
housing and financial needs, as well as representa- encountered was as diverse as the population.
tives from companies formerly located in the World
Trade Center. Food was available in cafeterias, and
AN
FOLD! G OF STORIES
places were allotted for children to play and for
families to rest. "There were also two long rows of Ten minutes after arriving at the pier, Pessar talked
attorneys whose job it was to take data and fill out with a woman referred by a Red Cross worker. The
death certificates," recounts Pessar. "Later, we woman lived in an apartment several blocks from
learned that the Department of Mental Health had the World Trade Center and, in the aftermath of
organized support groups for these lawyers because the attack, was extremely agitated.
"She kept repeating, 'I'm not crazy.' She had
they had heard some 3,000 stories."
At the pier, as well as at Ground Zero, a number of terrible post-traumatic stress disorder," says Pessar.
shrines had been spontaneously constructed. Pessar "What we did was talk about the events that had so
recalls that along one wall at the pier was a massive upended her life, and what it was she was dwelling
collage of photographs of the missing-people of on and worrying about. I reassured her that she
every ethnicity, age and appearance. The area was had a well-known and predictable syndrome and
roped off, and under the pictures were hundreds of that she would get 'all better' with quick linkage and
Teddy Bears sent from families in Oklahoma City. ongoing psychotherapy at a clinic."
Helping people identify and name what they
"People walked by and looked at this makeshift
were
experiencing was key to the psychiatrists'
shrine, and it was very moving for everyone," says
Pessar. "Again, 1 think this was an attempt to use work. "I think the most important advice we gave
ritual as a way of containing people's grief and fear." people was that their enormous emotional upUnder the aegis of Disaster Psychiatry Out- heaval was proper and that they didn't need to be
reach, the psychiatrists were asked to perform two afraid of their own responses," Pessar notes. If neckinds of services. One was to respond to requests for essary, in addition to talking with people, she and
formal evaluation made by the various agencies at the other six or seven psychiatrists working at the
the site on behalf of individuals they were assisting, pier also gave medications, but provided only a few
and the second was to walk around the pier and talk days' supply so that people wouldn't become comwith people who appeared distressed, with the goal placent about seeking further help.
Another encounter at the pier took place in the
of providing them with a quick linkage to longladies
room, where Pessar and Aronoff struck up a
term mental health services.
conversation
with an African-American woman
"What I remember most about the pier are the
who
appeared
outwardly composed. "This wonderfaces, the faces of tragedy," says Pessar. "You knew
whom to walk up to, and it was like nothing I had fully dignified woman in her mid-50s talked to us
ever seen. The grief had drained and etched them; about her faith, explaining that she was very relithe detail of suffering in their faces was exquisite, gious," says Pessar.

u

"\VIzat I remember
most about the pier
are the faces, the
faces of tragedy,"
says Pessar. "You
knew whom to walk
up to, and it was like
nothing I had n•er
seen. The grief had
drained and etched
them; the deta if of
suffering in their
faces was exquisite,
almost like what you
would see in a
painting."

�HE WOMAN ALSO TOLD THEM HER STORY,

"There were also two
long rows of tJttorneys whose job it was
to take data and fill
out death certificates," recounts
Pessar. "Later, we
leamed that the
Department of
Mental Health lznd
organized support
groups for these
lawyers because they
had heard some
3,000 stories."

explaining that she was a receptionist for
one of the administrators at the World
Trade Center and that she had been in the
1993 bombing and had escaped without
incident. On September 11, one of the
planes hit the tower very close to the floor
on which she worked. The ceiling fell in,
but she was unscathed.
"When she didn't get anything on her from the
ceiling, she thought that was a sign from God, that
God had created a shield around her to protect her,
and that calmed her," recounts Pessar. "One of the
secretaries on her floor was not so fortunate and was
consumed by a fireball."
The woman further explained that when the
plane hit, the building's sprinkler system was activated and all the doors in her office automatically
locked. She knew of a door that had been kept ajar
so people could go down to the level below and
smoke. She headed for this exit and proceeded to
walk down 73 flights of stairs.
"She described water pouring down on these
slippery steps and how she just tried to go step by
step while the firemen were rushing up," Pessar relates. "And she did escape. But, after telling us her
story, she said, 'I'm a religious woman, and my faith
is very important to me, but I've been through two
bombings, and I need counseling.' So before we parted, Helen provided her with referral information."
While working at the pier, Aronoff also recalls
going into a television lounge and finding an Ecuadorian woman curled up tightly on a couch, accompanied by her four-year-old son and her sister.
Aronoff sat on the floor and talked with them for
about half an hour, relying on her limited proficiency in Spanish and the sister's equally limited
English to piece together their story. She learned
that the mother had recently left behind three other
children in her homeland to come to the United
States with her husband, who was in the World

Trade Center and was missing. When Aronoff asked
how the boy was doing, she discovered that the
mother was very concerned about him.
"She told me he was 'acting like a baby again,"'
says Aronoff. "He wanted to sleep in her bed, was
clinging to her, was enuretic and was having temper
tantrums if he didn't get what he wanted. And she
didn ' t know what to do about it because she was
barely able to function day to day herself. So I
focussed on giving her support, and I think that
was very helpful to her. "

No

E

D To THE NEED

As intense and draining as these patient encounters
were, Aronoff and Pessar found that their work
didn ' t end when they left the pier. Each night when
their shift was over, they boarded one of the buses
provided by the city that stopped at subway stations
and other locations in order to facilitate transportation for people traveling to and from the pier to
receive services. As it turned out, these bus rides also
proved fertile ground for counseling sessions.
On one occasion they met a woman on the bus
whose fiance worked at the World Trade Center as
a carpenters' supervisor. He was called in to work
that day and had died in the attack.
"The woman told me they had planned to marry
and that they had custody of his two small children,"
recalls Pessar. "She was accompanied by the man's
sister, who herself had recently been widowed and
had no living relative except her brother. So these sad
women had come to the pier only to discover that
because the woman was not legally married to the
carpenter, she was not entitled to any benefits.
"And this was quite common in terms of what we
found," continues Pessar. "The pier was populated
by people who represented all kinds of domestic
catastrophes. These were the families of the janitors,
the secretaries, and the cafeteria workers in the
World Trade Center. Most had scanty resources to

�begin with, and many saw all those resources disappear. They needed to be advised about psychological
services and given practical advice."
On another bus ride, Aronoff remembers meeting and talking with a husband and wife who had
come from south New Jersey because the woman's
brother had been killed in the attack. "They were
planning a memorial service," says Aronoff, "and
they wanted to get as close to Ground Zero as
possible just to get a cupful of dirt so they would
have something to remember him by."

GROU

D THAT DEFIES DESCRIPTION

On Friday, the second day they were in ew York
City, Aronoff worked at Ground Zero in the morning, while Pessar and Pristach worked there in the
evening. All three women relate that it is difficult
to put into words their first impression of Ground
Zero, saying simply that it defies description. Each
says she was initially struck by the vastness of the
space, approximately 70 acres of dirt and gray
mountains of rubble.
"On the periphery are cinder-stained buildings
with windows blown out and sections of the World
Trade Center imbedded in them; and this is Manhattan! " recalls Pessar.
Adding to the disorienting effect produced by the
obliteration of streets and other directional cues was
the fact that at night the site was artificially lighted,
which gave it a garish, foggy atmosphere made all the
more lurid by the smells that hung in smoke-filled air.
Dotting the site, as at the pier, were a number of
shrines, where exhausted and dispirited workers
stopped to pray.
"Everywhere you looked, there was this eerie
contrast of the sacred and the profane," says Pessar.
"Among the workers, there was a sense of enormous
grief, but enormous purpose and patriotism, too.
This was a sacred site, sacred to all of us because of
the death and because we were Americans and felt

we needed to protect it; but then it was a hellish
place, too."
Along with the grim mood and somber respect
evoked by destruction and death, there was a strange,
almost carnival-like atmosphere that developed at
the site, as well.
"Amidst the ruins, there were rows of tents with
free food of every kind," says Pessar, "and booths
full of new clothes, boots and socks, all free for the
taking; heaps of stuffed animals for your children;
and places where you could make free calls home. It
made me think of Pleasure Island in the Pinocchio
movie. And then there was this pile of rubble with
3,000 human remains."

MEMORIES OF THE

U

IMAGINABLE

At Ground Zero, the psychiatrists' first task was to
meet with the disaster medical assistance teams
(DMAT), which are teams of health professionals
mobilized by the federal government during emergencies. There were five DMAT teams on the perimeter of the site, and it was their job to respond to
any medical emergency, whether it be a cut finger
or more serious situations. As was the case at the
pier, in addition to responding to formal requests
for evaluation, the psychiatrists were expected to
approach people at the site-construction workers,
firefighters, police, and members of the National
Guard-and to provide counseling if needed.
A crucial aspect to work at Ground Zero was
helping the workers validate their experience, according to Pristach. "Although nobody was saying
it officially, during the four days we were there,
work at the site was transitioning from rescue to
recovery. The workers digging through the rubble
needed help validating that they were living
through the experience and that what they had
been doing was in some way helpful," she says.
In one instance, Pristach and Pessar had a lengthy
conversation with a high-ranking firefighter who

The woman further
explained that when
the plane hit, the
building's sprinkler
system was activnted
and all the doors in
her office automnticnlly locked. She
knew of a door that
had been kept ajar so
people could go down
to the level below
and smoke. She
headed for this exit
and proceeded to
walk down 73 flights
of stairs.

�On another
occasion, Pristach
says she was
approached by a
firefighter who was
concerned about a
coworker who had
fallen five stories in
one of the towers
and had survived,
but was not coping
well in the aftermath.
"He told me that his
friend was shaking
like a leaf at home
and that nobody
knew what to do for
him," she recounts.

they said "just needed to vent." He explained how the
younger firefighters looked to him for support and
guidance but that, as a leader, he had few people to
turn to for comfort. He was exhausted by the continuous 12-hour shifts he had been required to work
and was concerned about new manpower shortages
the fire department was experiencing as a result of the
disaster. He explained that, in addition to the many
deaths among his ranks, SO new recruits had decided
to rethink their career paths, putting pressure on
older firefighters not to retire as they had planned.
"He was not only grieving the loss of his coworkers and time away from his family, but the
fact that everything in his life had been displaced,"
says Pristach. "And the worst thing was he felt he
couldn ' t complain because so many had died."
On another occasion, Pristach says she was approached by a firefighter who was concerned about
a coworker who had fallen five stories in one of the
towers and had survived, but was not coping well in
the aftermath. "He told me that his friend was
shaking like a leaf at home and that nobody knew
what to do for him," she recounts. The firefighter
gave Pristach the man's phone number, which she
then passed on to a local outreach center for appropriate intervention.
Pessar says she found people at Ground Zero
more reluctant to talk than at the pier, but that the
older firefighters, in general, were more open about
their feelings than their younger colleagues. "They
had nothing to prove," she says.
While working at the site, she recalls being pulled
aside by one such older firefighter who said, "Can I
speak with you, Doc?" He then began telling her
how he had been off duty when he heard the reports
of the attack on the radio and had come to the
World Trade Center to help. He was in the second
tower when it collapsed and was saved by being
thrown under a metal table that protected his
head. He was rescued from the rubble, given last
rites and hospitalized for ten days.

''

from the hospital he became preoccupied by the fact
that his injuries were not on his face,"
says Pessar. "He didn't have any legitimate markings of his involvement, and
he thought that there were rumors in his
neighborhood that he was lying about his
experience."
Again, Pessar found it important to
help the man name what he was experiencing and
to be assured that it was normal. "So we talked
extensively about survivor guilt, and I tried to help
him understand what he was feeling," she says.
"We must have talked 4S minutes; it was really a
psychotherapy session, and as we finished I asked
him to link up with services offered through the
fire department and he promised me he would."
For Aronoff, one of the most lasting memories
of Ground Zero pertains to seeing families of the
victims who were brought to the site by Red Cross
workers to say their final good-byes.
"The first day I was at Ground Zero, the Red
Cross began escorting family members by ferry
boat from the Family Assistance Center over to
Ground Zero in groups of about SO at a time," she
explains.
FTER HE WAS DISCHARGED

"When the first boatload of families came, it
was a very moving experience because we were
literally standing at the site of the twin towers and
all of a sudden from one of the side streets came a
group of people who were clearly not rescue workers. They were holding on to each other, holding
Teddy Bears, holding flowers, and were absolutely
silent as they walked past the towers. Spontaneously, every one of us working at the site took off
our hard hats and held them to our hearts," she
says. " It was incredibly painful, and it happened
three or four times while I was there."

�TIME

To Go HoME

After four days, the remarkable ordeal of these three
psychiatrists came to a close and it was time to
return to Buffalo and their families, practices and
students. In attempting to sum up the enormity of
their emotions surrounding this experience, they
expect it will take months, perhaps years, to fully
absorb what they encountered.
All agree that the experience is one they never
would have forfeited, and they relate wholeheartedly to Aronoff when she says, "I felt like it was an
honor to go, to be called to help. You never really
know how much individual help you provided, but
I think none of us feels our time was wasted. For
me, at least, I was glad to have a
chance to be able to give something back."
Echoing Aronoffs sentiment, Pessar adds, "I think all
three of us-Cindy, Helen and
I-are fairly idealistic. And I
know that when I went to
medical school, I was taught
that medicine is a calling.
"During the time we were in
the city, there was a sense of
responding to one's calling. I
think this is something all three
of us felt; and it was a privilege
to respond."
CD

Drs. Pristach, Pessar and Aronoff
would like to thank Dr. Susan
McLeer, chair of University at
Buffalo's Department of Psychiatry, and other administrators
in the School of Medicine and Biomedical Sciences
for allowing them to take time away from their
normal schedules to travel to New York City to work
with Disaster Psychiatry Outreach.

.-

hllall ,.rslclu

I

�---

--

Buffalo Physician readers write about September 11

[~itor'snote: J allowing the tcrrorists'attacks zn" 'cw York, \\ ashington, DC,

Waiting for Few Patients

and Pcnnsylmnia on September 11,2001, "\litlwel Bcmard111o, AID, dean
Bv

ALEXANDER VoLFSON. CLASS O F 2002

of the Unn·ersity tlt Buffalo School of Medicine and Bio111CdJml Sciences,
conl'eycd in

11

letter to alllllllll, flu ulty and students the deep sorrow and

disbelief our UB COIII/Illllllt)' felt in the ajtermath oj tillS tragi( day. Dean
Bernardino also expressed concern

f(Jl·

the saJcty of our school's alumni,

explaining that some 1,550 lil'c and \\'Orkin the New York Cit)' area, and
anaddit1onal600 or more within a 45-minute dnve of\\'ashington, DC
At the

cl(N

o( Ius letter, he inntcd ltllhl'Jduals to contact Buffalo

Ph) sician should they lun•e stories they "1shcd to tell about e1 cnts

surrounding eptC1nl1cr 11th.
Here arc so11zc of tilt' responses \\'e receJ\'cd.

n September 11th I was in the fourth week of an
anesthesiology elective at ew York Presbyterian Hospital/Weill Cornell Medical Center and
spent most of the day in the emergency room.
Once I rea lized the scope of what had happened, I felt shocked and scared, but definitely
proud to be in a position to help. When the hospital
went into emergency mode, there was no panic;
everyone just came together and worked calmly.
Physicians from all specialties were divided into
teams, each assigned to an ER station. There were
nurses, students and other staff there as well. Volunteers passed out food and drinks, and we had
shifts so that no one would get tired. Unfortunately
there weren't too many patients to treat.
Cornell has a big burn center, and many patients
were directed straight there, bypassing the emergency room. We took care of a few firefighters and
police who suffered minor inhalational injuries. Several buses took doctors to the Chelsea Piers, where a
triage area was set up. At one point, the discovery of
the bodies of two EMT workers brought to tears
many of the people in the ER who knew them. But
everyone remained calm and continued to work.
At the end of the day, a couple of us went to get
some pizza at a nearby pizza shop. As we walked in,
the customers there began to applaud us. It was a
great feeling knowing that you were part of a special
group of people who know how and a re ready and
willing to help others.
CD

�SORE SPASMODIC
SO

ET U

SU

G

VESALIUS EXFOLIA T
SUBJECT DESCE

DI

FREE OF GALILEO A

G

D

EWTON BOTH

AT 0

E POI T, THE

DISCOVERY OF THE BODIES
OF TWO

EMT WORKERS

BROUGHT TO TEARS MA Y
OF THE PEOPLE I
WHO K
EVERYO
A

THE

ER

EW THEM. BUT
E REMAINED CALM

D CO TI

UED TO WORK.

�Grey Sonnet Following the Cloud Solace and Inspiration
BY EDWARDS. CHESLOW,

MD

'81

Cataclysmic Convulsions Imploding
Laden in grieving horror of chagrin

As the initial
Witnesses all too complicit in expedient libel begin

numbing phase
Substitutive Echo of the Enigmatic Hate

began to wane,
Unpardonable Occurrence action we mistake

the psychiatric
repercussions of this
trauma began to
surface. \\'e saw
immigmnts with
post-trcwnwt1c stress

Immediate nearly complete in lethality
aftermath unrest
Incalculable misery seed to vitiate our unsoiled
mighty granite nest
Sore spasmodic sonnet unsung
Vesalius' exfoliant subject descending

disorderfrom war-

Free of Galileo and Newton both

tom countries who

Terminal velocity of neither feather nor weight

were rc-tmumatized;

Applied accelerant to both Human body
and symbol

in at least one case I
either hope nor solution this

encountered, this led
Innumerable Particulate

to psychotic dcc0111pcnsation requiring

Or Clzeslow" a, Ticholas Ra11go Fellow i11 HI\'
,\fedu i11c at the 4IDS Institute, \lowlt Si•m1 S( fwol

of A!ed!Wie, m, 1cw York City

hospitaliza tio 11.
CATHY BUDMAN

BY CATHY BuDMAN,

MD

'84

am an academic psychiatrist on staff at the
orth Shore-Long Island Jewish Health System,
approximately 20 miles from Manhattan. While
our staff remained on alert, anxiously awaiting
for what we expected to be the many injured,
we could see the smoke from the burning towers
from our hospital. To our horror, the patients
never arrived.
The devastating reality for health-care workers
throughout the ew York metropolitan area on
September 11 was that there were no large numbers
of civilians to be saved. Many, many people perished without tangible remains. Forty to 60 people are
missing from my hometown, Manhasset, on Long
Island. Some families are missing two siblings, or
both parents. In the majority of cases, there are no
whole bodies to retrieve, only body parts that were
gruesomely dispersed throughout the rubble. The
human loss is overwhelming.
On a personal level, this catastrophe impacted
directly on my sister and her family. They became
homeless, the children's elementary school was
destroyed, and my sister's office in the American
Express building was used as a morgue. And my
sister-in-law, who survived the 1993 tower bombing, managed to safely evacuate from the
ninth floor of Building 7, which later collapsed.
Both witnessed the carnage: the terrifying crashes
of both planes into the towers, the desperate
people jumping from the upper floors, those killed
by falling debris on the streets, and the tidal waves
of dust and debris that followed the collapse of the
towers. Of course, they have lost neighbors and
colleagues. We feel blessed that our immediate
family members are alive.
For the first few days after the disaster, my office
at the hospital was unnaturally quiet. We spent
some time counseling emergency medical service
personnel from Long Island, many of whom were
at Ground Zero but unable to find survivors to
help. Many had lost colleagues and friends from
the various fire or police departments.

�September 11,2001
BY LARRY BEAHA

' .MD

'55

t's like On the Beach. What would you like to do
As the initial numbing phase began to wane, the '
on the last day of your life?" my wife, Lyn, said.
psychiatric repercussions of this trauma began to
We were launching our tandem canoe into the
surface. We saw immigrants with post-traumatic
Erie Barge Canal on our way for apple strudel
stress disorder from war-torn countries who were
at Omi's Deli across the water. A battered Stars
re-traumatized; in at least one case I encountered,
this led to psychotic decompensation requiring and Stripes dangled at two-thirds mast as brilliant
sun turned a cotton-spattered sky unreal baby blue.
hospitalization.
"If this is the last day, it will do," I said.
We saw families reeling from the unimaginable
loss of loved ones, in many cases involving young
That morning as I was at work on my computer,
people with young children. We saw elderly who Lyn came in breathless: "They just crashed a jet into
had survived America's wars overseas and who the World Trade Center." We rushed to the televiwere now heartbroken to experience it on our soil. sion as another plane exploded the second tower in
We saw paranoid-schizophrenic patients who were orange flame. It was unbelievable. Like watching
delusionally convinced that they had actually King Kong climb the Empire State Building. It lookcaused this disaster. We saw Moslem patients who ed like a trick. The audio portion was Orson Wells
were afraid to leave their homes lest they be threat- and his "War of the Worlds" over again but there
ened and beaten. We saw angry, depressed adoles- were no disclaimers.
cent boys filled with fantasies of rage and retaliOur son, Teck, called from work. "Did you hear
ation, as well as many patients with anxiety disor- what happened?" he said.
ders and depression who were experiencing severe
Yes, we did, and we recalled a pilot with a Kenworsening of symptoms. Many children were pre- more connection who was killed when his B-25
senting with somatization and conversion disor- crashed into the Empire State Building in fog, and
ders. We expect the need for psychiatric services will Kennedy's death. Curiously, I remembered the
only increase as time goes on.
bowl of oyster crackers I ate in a Deco restaurant
Being a doctor has provided me with great solace when the Pearl Harbor news came over the radio
and inspiration during this crisis. I appreciate more that day my dad had taken us Christmas shopping.
than ever the gift of being able to help others. Each
Our out-of-town son, Nick, got through on the
day brings new challenges and opportunities to phone. "We haven't heard how Pat and Mike are,"
exert one's humanity, and for this I am so very I said. Our niece and her husband have a tiny rentthankful.
4D controlled apartment they inherited in lower
Manhattan. He works in the Financial District.
"Thank God you aren't flying today," Lyn said.
Nick said, "Isn't Patty's baby just about due?"
I remembered the Bay of Pigs. I was in the Air
Force on temporary duty in the U.S. Lyn and our
kids were on a troop ship sailing from our home
base in Japan to meet me in Hawaii. While we were
there, Teck and I watched from Waikiki as a hydrogen bomb, tested 600 miles from us, ignited the
en tire Pacific sky.
As New York rocked in the aftershocks of the
World Trade towers, we watched and watched the
death and destruction on television. Reports of the
Pentagon crash and of another jetliner in Pennsylvania came in. A friend e-mailed, "What if that jet
went into the nuclear reactor at Three-Mile Island?"

\\'e recalled a pilot
with a Kenmore
Connection who

\\'{IS

killed when his B-25
crashed into the
Empire State Building in fog, and
Kennedy's death.
Curiously, I remembered the bowl of
oyster crackers I ate
in a Deco restaurant
when the Pearl
Harbor news came
over the radio that
day my dad had
taken us Ch ristmns
shopping.
-LARRY BEAHAN

�That afternoon in
the canal and at
Omi's, it might fum.'
been the last day of
our ln·es, so Lyn and
I rclJShed the sun,
the \Vlltcr and a great
blue heron's flight.
\\'c paddled our
canoe doH 11 the

canal and across to
the do(k at Omi's
little dclzcatesscn.
-

I
f

1•

LARRY BEAHAN

~

I 1 f f a f 1 P ys i ei a1

That evening I had two meetings I was planning
to attend. Both were cancelled. I argued with one
chairman who felt we must mourn rather than
meet. I believe it would have been better for our
groups to meet and talk and plan joint action,
maybe a carpool to the Red Cross to donate blood
or to pray. Staying home glued to the one-way
communication of the television screen
does little for me.
That afternoon in the canal and at
Omi's, it might have been the last day of
our lives, so Lyn and I relished the sun,
the water and a great blue heron's flight.
We paddled our canoe down the canal
and across to the dock at Omi's little delicatessen. Omi, the transplanted German
grandmother with her big smile, her bad
hip and her full-length apron of pale roses, was flustered. " o, I didn't forget your soup. Who would
believe it, how could it happen in this country?" I
accepted the hot chocolate she brought instead of
the chocolate milk I ordered. "Everything is
discombobulated this morning, "she said.
An elderly couple arrived by bicycle and took
their tea and brownies outside in the sunshine. "I'll
pay, you paid last time at Mississippi Mudds," she
said. Apparently it was their second date.
Omi called, "How do you want your strudel, hot
from the oven or cold?
"Hot, I love it hot," I called back.
Two young women talked, one in a bright red
dress with a watermelon-size bulge in front, the
other in similar red top and white pants but carrying her newborn in a car seat. "I like to make a big
pile of spaghetti with a red meat sauce," one said
as the other picked up with her ideas on how to
make pickles.
Omi, between serving her Transylvanian horseradish soup and delicious flaky, tart-sweet strudel,
talked of war: "You tell me how that was possible,
in this country. In Germany the airports have soldiers with machine guns. Here we pay inspectors
minimum wage. When she interviewed me, Janice
Okun loved this soup. I got one granddaughter,
lives twenty miles from the Pentagon."
One of the mothers peeked at the baby in the
basket. "He's nodding. They do that, you know,"
she said: then, "I just sat and watched an airplane
fly into the World Trade Tower. You know how
sometimes you can't grasp what you're looking at.

IV , ,

r ,. r

1 oo2

I couldn't believe it. Jt was like something in the
Third World."
I went to the counter to pay Omi. She was
working on a sandwich as she talked on a cell
phone tucked under her tilted chin. "Bye, bye
Shatzi. I love you too. Goodbye," she said; then to
me, "All my kids are calling. I charged you for the
lunch special since you had the sandwich and your
wife the soup. Was everything okay?"
"That strudel, just hot out of the oven, was
wonderful."
"I know, but some people only like it cold. You
have to ask."
I tried to tell her about Lyn's On the Beach
question- "How would you like to spend your last
day?" I don't think I got it through Omi's
"discombobulation" that, if this had to be our last
day, then a paddle on the canal with Lyn and
strudel at Omi's would do fine for me.
That evening my sister e-mailed me, "Mike got
home covered with dust. He helped rescue workers
till there was nothing more he could do. Pat and
the baby are okay."
CD

Dr. Bcaha11 ;, a rcttrcd p:-rclzl&lt;ltn~t mui c111thor o(Mv
C.randp.1\ \\'oods, th~ Admmd,1cb. 1-h lives 11ot far
from where the Fnc Hargt Canal pa:scs througlz 'orth
f'otull\'&lt;lllda,
'ew York. 1-lt• wrote thi.&lt; story 011 the
Cl't'lllllg o('\eptl'll!bcr II, 2001.

ADay in Downtown Manhattan
BY HAROLD BRODY , MD '61, PHD

hile on a visit to ew York City to see my
cousin on October4, 2001, I took the opportunity to travel into downtown Manhattan
to visit the area around what was formerly
the World Trade Center.
Since my cousin lives on Broadway and West
I 1 I th Street, I rode the subway downtown to two
station stops before Canal Street and walked the
remainder of the way to the site. Leaving the subway, I was immediately struck by how few people
were on Broadway. Uptown, there had been about
100 persons per city block, while downtown there
were only two to four people per block.

�"IT's LIKE ON THE BEACH. WHAT WOULD
YOU LIKE TO DO 0

THE LAST DAY OF YOlJR

LIFE?" MY WIFE, LY

, SAID. WE WERE

LAUNCH!

DEM CA

G OUR TA

ERIE BARGE CA AL 0

OE INTO THE

OUR WAY FOR APPLE

STRUDEL AT 0MI'S DELI ACROSS THE
WATER.

A BATTER~D STARS A D STRIPES

DANGLED AT TWO-THIRDS MAST AS
BRILLIANT SUN TUR
SPATTERE

SKY U

ED A COTTO

-

REAL BABY BLUE.

MY ONLY HOPE IS THAT WHAT
ALSO LINGERS IS THE RESPECT
AND REGARD THAT PEOPLE
SHOWED EACH OTHER AT THE
SITE. IT SEEMS A PITY THAT WE
MUST GO THROUGH AN
EXPERIE

CE LIKE THIS TO

DEVELOP A

ATTITUDE OF

REGARD AND RESPECT FOR EACH
OTHER. BUT PERHAPS THIS
PAl

FUL LESSO

WITH US.

WILL REMAI

�I went into a hardware store to speak with the owner, who said
that the streets had been desolate since the World Trade Center
was destroyed and he could not see how he and his family could
remain there for very long, given the drop-off in customers to
his store.
Restaurants were empty, hardly a car passed by, and I saw few
police patrolling the area. In short, there was a feeling that everyone had forgotten the existence of this part of the city, where even
24 days after the attack, a cloud of smoke hung in the air.
As I neared Canal Street I noticed that store fronts and apartment houses were covered with thick deposits of ash. There was an
increase in the number of pedestrians and police, although automobiles, including taxicabs, were virtually absent.
Pedestrians were restricted to walkways that had been built
on the sidewalks. We could venture as far as one street from the
periphery of the damaged area, but no closer. The number of
police in this area was very great and they were clearly in charge.
Looking toward Ground Zero, the amount of damage I observed was incredible. o buildings were standing in the area;
everything had been destroyed. Occasionally, people walking by
would wipe tears from their eyes.
As we stood observing the work at the site, no one smiled or
laughed. There were few young adults in the area, and I saw no
children.
The area around Wall Street, assau Street, Fulton Street and
the former World Trade Center is normally very noisy. Yet while
I was there, I was struck by how quiet it was. When people spoke,
they kept their voices low. o one shouted, everyone was patient,
and there was a total regard for the next person, as well as a
gentleness toward complete strangers.
In talking with people I encountered, l often sensed confusion
in their minds about how to respond to what had happened. While
they wanted some form of retribution for those who had created
this hell and killed so many thousands without regard, at the same
time they were very sad, and several remarked that they wanted to
cry as they looked at the broken buildings and debris. Many talked about struggling with the realization that life must go on.
You have to leave this area before you can overcome the feeling
of dread that envelopes you while you are there. And the feeling
does not disappear completely once you've left, but haunts you
for hours and days after.
My only hope is that what also lingers is the respect and regard
that people showed each other at the site. It seems a pity that we
must go through an experience like this to develop an attitude of
regard and respect for each other. But perhaps this painful lesson
will remain with us.
4D

Dr. Harold Brody 1sa lh&lt;tmguishcd fcaclung Projl·ssor l;mcntus of
anatomical sciences in the Ulllvcrsit)' at Bu{fi1lo School of.\lcdicillc
a111f Biomedical Scic11ccs.

lhttp://www.sciam.coml

attacks are most at risk fo~ post-traumatic stress disorder
feel much more vulnerable. Author Sarah Graham discusses wliat
events in this article on the Scientific American web site. An
internet study lhttp://coping.stanford.edu/J launched on
September 22nd attempts to assess responses to the attacks on
America. The article also offers a set of do's and don'ts for
coping with anxiety and links to other relevant topics.

mental heaHh services to those who have survived disasters such

also available in print, free of charge, from the Center for Mental

�ALUMNI

Oistin~ished Medical Alumnus Named
Marshall A. Lichtman, MD '60

arshall A. Lichtman, MD '60, received the
University at Buffalo's Distinguished Medical
Alumnus Award from the Medical Alumni
Association at a dinner held on September 20,
2001, at the Buffalo Club. Lichtman is former
dean of the University of Rochester School of
Medicine and Dentistry and former executive vice president
for research and medical affairs for the Leukemia and Lymphoma Society of America.
After graduating from Buffalo's Lafayette High School,
Lichtman attended Cornell University, where he earned a
bachelor of arts degree in zoology. He then entered the thenUniversity ofBuffalo School of Medicine, graduating in 1960.
Lichtman spent his entire academic career at the University of Rochester. He completed his residency in internal
medicine there in 1963, after which he served in the Public
Health Service until1965. He then returned to the University
of Rochester to serve as chief resident in medicine.
After completing his residency training in 1966, he pursued a strong interest in hematology and was awarded a Special
Postdoctoral Research Fellowship from the National Institutes of Health from 1967 to 1969 to conduct studies on the
biochemistry and physiology of blood cells and their abnormalities in leukemia. In 1969, he was named a Scholar of the
Leukemia Society of America, an honor that was complemented by research support from the National Cancer Institute.
In 1968 Lichtman was appointed assistant professor of
medicine at the University of Rochester School of Medicine
and Dentistry and in 1970, assistant professor ofbiophysics.
In 1974, he was appointed professor of medicine and of
biophysics, and in 1975 he was named chief of the Hematology Unit. From 1979 to 1989 he served as dean for academic
affairs and research at the university, in addition to his
responsibilities as a professor, scientist and hematologist.
From 1990 to 1995, Lichtman served as dean of the
University of Rochester School of Medicine and Dentistry.
In 1996, he was named executive vice president for research and medical affairs of the Leukemia Society of America, now the Leukemia and Lymphoma Society. He also
retained his appointment as professor of medicine and of
biochemistry and biophysics at the University of Rochester.

Lichtman has served on the editorial board of five scientific journals and as the editor-in-chief of Blood Cells,
Molecules, and Diseases. He has been the editor of two
monographs and four textbooks of hematology, one of
which is in its sixth edition, and has authored more than
230 scientific articles and book chapters on the physiology,
biochemistry and disorders of blood cells.

Left to right: John Bodkin II, MD '76, president of the University at Buffalo's
Medical Alumni Association, Marshall A. Litchman, MD '60, and his wife, Mary Jo.

A Master of the American College of Physicians, Lichtman has been a visiting professor at over 40 medical centers
in the United States and Canada. He has served on the
Hematology Study Section of the National Institutes of
Health and as chair of the U.S. Navy's peer review group of
the Division of Biological and Medical Research. He is a
past president of the American Society of Hematology and
has been chair of the society's advisory board.
Lichtman also served on the Council for Graduate Medical Education of the State of New York and on the board
of governors of the American Red Cross. CD
-S. A.

UNGER

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��"There are about eight million new cases of TB worldwide
each year, 95 percent of which occur in the developing world,"
Miller says. "Unless we act aggressively to control and eliminate
this treatable and preventable disease, it will continue to take an
enormous toll."
The World Health Organization (WHO) estimates that
without dramatically strengthening public health control and
elimination efforts, one billion people will become infected
with TB within the next 20 years, 200 million people will become sick and 35 million people will die from TB. Moreover,
there are approximately 36 million people living with HIV
infection-some 5.3 million of whom became newly infected
in 2000 alone. To date, nearly 22 million people worldwide
have died from AIDS, and the number of individuals who
have been co-infected with this disease and TB-estimated to
be about 11 million people-is expected to dramatically increase in the next 10 years. Persons infected with both HIV and
TB are 50 to 100 times as likely to develop active TB as those
who are not HIV infected. As a result, rates of TB in subSaharan Africa, formerly 10 to 20 times higher than rates of
TB in the U.S., have doubled and tripled in the past 10 years.

"To prevent HIV infection is to prevent TB, and to treat
TB is to treat AIDS," Miller observes. "These two pandemics
are intimately linked, and the tactics to control them must
be synchronized."

1.1.1
a:
TO MAKE A DIFFERENCE

u; Born in 1947 in Racine, Wisconsin, and raised in Gary,

=

1.1.1 Indiana, Miller was encouraged to pursue her academic

interests by her mother, and equally imbued with a strong
sense of community and a desire to make a difference in
the world by her father, who is a rabbi. A career in public
health seemed the logical choice, Miller explains, because of its
scientific rigor and its potential to improve conditions for large
numbers of people.
With this in mind, Miller studied public health nutrition at
Harvard University, earning a master's degree in that field in
1970. Three years as a public health nutritionist whetted her
appetite for medical knowledge and prompted her to enroll in
medical school at the University at Buffalo.

C

"I loved Buffalo from the beginning," she says. "The

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�approach there was, and continues to be, very practical and
very patient oriented."
At UB, she adds, she found further inspiration to work in
the area of public health under the tutelage of such mentors as
Harry Metcalf, MD, UB associate clinical professor of family
medicine, and Robert Dickman, MD '68, then a UB professor
of medicine in the Department of Social and Preventive Medicine, who is currently chair of family medicine at Tufts University. Both professors, she says, conveyed a strong concern
for and awareness of community-oriented medicine. Her
interest in public health was further reinforced when she and a
fellow medical student, Benjamin Gitterman, MD '76, established a community board to work with the administration of
Buffalo General Hospital to enhance the hospital's responsiveness to the needs of the local community.

C PANDEMIC AND OTHER
..... INTERNATIONAL

Miller's interest in international health was sparked
by another unusual opportunity that came her way
during her two-year training with the Epidemic Intelligence Service. This time it was the chance to track down
the cause of an illness affecting more than 900 Palestinian schoolgirls on the West Bank of Israel. The
illness was characterized by headache, dizziness, abdominal pain and leg weakness, and many of the girls
were hospitalized.
"I was asked to participate in this outbreak investigation because I had previously worked in the Middle
East and because I was a woman," Miller notes. "We
visited five hospitals where the girls were receiving care
in wards accommodating up to 40 patients, generally
two to a bed. Some clearly appeared in distress, but most
were full of the bubbling enthusiasm and curiosity of
teenage girls. While all were wearing abbayahs and appeared appropriately modest, further examination re-

c::t CROSSCURRENTS

en After completing her internship and residency in internal

e

medicine at Washington Hospital Center in Washington,
.... DC, Miller moved to Atlanta to join the staff at the CDC
as a member of the Epidemic Intelligence Service, a practical training program in public health, emphasizing field work.
The year was 1981, a momentous time in public health, as a
puzzling affliction (a generalized lymphadenopathy syndrome)
had recently emerged among gay men and appeared to be
associated with the growing numbers of cases of Kaposi's sarcoma and Pneumocystis carinii pneumonia in the same population. Miller spent months in ew York City investigating the
condition. She and her CDC colleagues produced the most complete description of the syndrome, which is now known to be an
early manifestation of HJV disease.
"The experience was life changing because we were seeing
so many vibrant young men in the prime of their lives with an
unknown illnes ,"she says. "We conducted extensive interviews,
drew blood specimens for the virologists in Atlanta, and reviewed thousands of pathology records to look for a pattern. We
found one: There was an increase in generalized lymphadenopathy in ew York C ity among homosexual and bisexual
young men between 1977 and 1981. This syndrome appeared to
be linked to the illnesses affecting gay men. In a few years, nearly
all of the men we had interviewed would be dead."

en

20

laffale PhysiciaA

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.....
a:

1111

.....
a:
.....

...:z:

w

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:

�asks, 'What are the major health issues for this
community and nation? What causes the greatest burden of disease and loss of productive
life? What is the cost to the community and
nation in terms of economic development
and quality of life? '"

a:1!5

BEFORE THE STORM

vealed that most were wearing blue jeans and tee shirts beneath
their traditional dress. I was filled with feelings of tenderness.
"Thankfully, we were able to rule out organic disease and toxic
exposures and to rapidly identify possible trigger factors for what
turned out to be an epidemic of mass psychogenic illness. Despite
the political tensions of the region, the CDC's structured, epidemiologic approach helped calm the situation, and we were able to
put a community's concerns over this immediate worry to rest. "
Although she found such detective work fascinating, Miller
left the CDC in 1983 in favor of a clinical practice as an internist. As much as she enjoyed working with patients, however,
she found that she missed the breadth and scope of public
health work. After two years, she returned to the CDC, this
time taking a position with the Division of TB Elimination,
where she could combine her interests in clinical medicine

Miller's first years with the Division of
TB Elimination in the mid-1980s were
.... fairly quiet, she recalls. Because the pub:Z:: lie was not yet aware that the Pandora's
.... box of tuberculosis had been reopened,
federal funding was sparse. Miller primarily
worked in the U.S., consulting with state and
local TB control professionals on public health
practice. The link between TB and HIV infection was just becoming apparent in the U.S. ,
and much of Miller's writing and consultation
were focused on this connection.
As this assignment involved less
travel, it gave Miller and her husband, Steve Solomon, an
infectious disease specialist who works on patient safety
and health-care quality at the CDC, an opportunity to
settle in and concentrate on raising their two sons,
David and Matthew, now ages 17 and 14.
"I like the fieldwork. It's energizing and allows me
to learn about the concerns of health-care workers
and the people in the community involved," Miller says.
"However, when the boys were younger, I felt strongly
about not being away from home too much. Now, they
beg me to leave!" she jokes.
On a more sombre note, she adds that following the
September 11 attack on New York City, CDC staff
continue to travel and work abroad. However, they
closely monitor all State Department warnings regard-

and public health.
Part of the balance she strives to achieve between practicing
clinical medicine and public health comes from her work at a
weekly TB clinic in Dekalb County, Georgia, where she has seen
patients for the past 12 years. "I like the mixture of the political,
analytic and medical features of public health," she says. "At
the same time, my clinical work keeps me grounded. "
Miller emphasizes, however, that a supervening challenge
for everyone working in public health is getting public and
private sectors to communicate. "The world of private medicine is geared toward the individual patient, primarily toward
illness and cure, although it is becoming more prevention
oriented," she says. "The focus of public health, on the other
hand, is the entire community. The public health practitioner

ing specific destinations.
Despite the increasing incidence ofTB, control of the
disease remained a low priority throughout most of the
1980s. Late in the decade, however, reports of the spread
of multidrug-resistant TB jolted the U.S. public out of
complacency. The mounting HIV/ AIDS crisis prompted
further concern as epidemics ofTB among AIDS patients
were reported in hospitals, prisons and other institutional settings where persons infected with HIV lived or
received care. As a result, numerous public and private
foundations entered the fray against the disease at both
the national and international levels, and Miller soon
found herself at the forefront of well-financed efforts to
bring TB under control.

U

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GLOBAL HEALTH PRIORITY

.... So alarming is the modern TB pandemic that WHO declared
it a global emergency in 1993. In 1998 the organization
C launched the STOP TB Initiative, a global partnership to increase resources and move worldwide TB control higher up on the
international public health agenda. Since then, numerous partners have joined this initiative, including United ations agencies, private donors, universities, professional societies and
nongovernmental agencies. Miller has represented the CDC on
this initiative and strives to promote collaboration between the
Global AIDS Program and the efforts of STOP TB.
TB control is particularly challenging in developing countries
in Africa, Asia and Latin America, where TB and HIV/AIDS are
prevalent and health-care infrastructures may be weak. In an effort to improve control in all settings, WHO promotes the
Directly Observed Therapy Strategy (DOTS) for TB.
"This strategy requires political commitment on the part of
the government of each country, a stable supply of anti-TB
drugs, direct observation of each patient's therapy for six to
nine months, a network of laboratories to perform microscopic
examination of sputum, and a recording and reporting system,"
says Miller. "Political commitment is the key, however, because
TB control efforts require perseverance."

:Z

A major hurdle in the battle against TB is the tendency for
patients to discontinue treatment prematurely. "TB is a very
slow-growing organism, and it takes six to eight months to treat
it," Miller explains. "Because it's time consuming and labor
intensive for patients to complete the regimen, it's not surprising that many drop out of treatment after the symptoms go
away, even though they still have the disease. "
The result may be an increase in drug-resistant disease in the
community, Miller notes. When people fail to complete standard
treatment regimens, or are given the wrong treatment regimen,
the persisting bacilli may include organisms that are res istant to
one or more of the anti-TB drugs. These individuals may then
transmit these drug-resistant organisms to the people they infect.
Multidrug-resistant TB requires up to two years of more toxic,
less effective chemotherapy and may be up to 100 times more
expensive to treat than drug-susceptible disease.
"All of these activities require a strong primary health-care
infrastructure, which is critical for the improvement of the health
sector in developing countries," Miller explains. "However, these
activities are significant challenges for countries where the per
capita health expenditure may be less than five dollars a year."
There is a great need for new drugs, a shorter treatment
regimen, an improved and more effective vaccine than BCG, and

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new tools to make the diagnosis of TB quicker and
easier in the field, Miller stresses. "It takes years of
research to develop effective new drugs, and large financial commitments to fund that research. Given that
TB is a 'poor person's disease'-afflicting homeless
people, prison inmates, refugees and people with HIVthe market for TB drugs isn 't very lucrative. This tends
to inhibit research in this area," she says.

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1::::1 Despite these challenges, Miller is optimistic that

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c:::» where HIV infection is prevalent. "Though TB is

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by far the most common opportunistic infection
associated with HIV infection, it is treatable and
preventable, provided that treatment is begun
early and carried through to completion," she says.
The growing collaboration among international
agencies, governments and private donors seeking
solutions to TB and other health concerns greatly
encourages her. In 1998, for example, WHO launched
a massive effort toward elimination of "diseases of
poverty, " including malaria, HIV/AIDS and TB .

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Recently, the CDC has also substantially expanded and formalized its efforts in the international arena, a direction that
has been supported by Congress.
"This past year, as part of the STOP TB initiative, a Global
Alliance for Drug Development, spearheaded by the Rockefeller
Foundation, has been created to promote new drug development
for TB, which is really quite thrilling," Miller points out.
Scientific progress offers additional hope. "The genome of
the TB bacillus has been sequenced. That's a huge breakthrough
that will have a great impact on treatment and vaccine development. All of this makes me optimistic. The TB bacillus is a very
complex and tenacious organism, but we have finally moved into
the 21st century and are poised to eliminate it."
Miller encourages medical students to consider a career in
public health as an opportunity to make a difference for entire
populations. "When I was in medical school, I don't think many
of us looked to public health practitioners as role models. But
since then, I've been impressed by the creative, inspiring professionals contributing to this field of medicine. In the arena of
TB, with the enormous burden of disease it imposes on world
health, the challenge to public health practitioners is tremendous
and thoroughly motivating. I feel privileged to be among those
responding to that challenge."
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Honors Convocation Reco nizes
first· an Second-Year Achievements
ur

A

\

Hr) rw&lt;;

Co ' ·oc \flO recognizing academic excellence

among first- and second-year students at the University at Buffalo
School of Medicine and Biomedical Sciences was held in Butler

in general and systemic pathology. Dr. john
Sheffer practiced pathology in Buffalo for
over 35 years and was acting chair of the
Department of Pathology from 1972 to 1974.

Auditorium October 6, 2001.
The following is a list of award recipients and a description of the

Elizabetb laurke, '03, received The
Department of Pathology' s

awards received.

Departmental Awards

CARl- .

level in the laboratory portion of the courses

the second-year student achieving the highest grade in the microbiology and immunol-

American Society of Clinical
Pathologists Award for Aca-

The departments of the School of Medicine mzd
Biomedical Sciences have established awards to
recognize meritorious performance in their
courses as well as outsta11di11g achievemerzt i11
other curriculum-related activities.

Iarin Llrb•anee,'13,

outstanding performance in the

received the Department

pathology laboratory.

Carea Cellia, '14,

received the Department

ofMicrobiology' s Marek

of Anatomy and Cell Biology's
Gibson -A twell - jones Award,

Zaleski Award, which is
prese nted to the student

ment of Pharmacology and

which recognizes the student
with the highest combined average in the anatomical sciences
courses of gross anatomy, histology, neuroanatomy and embryology. The award is named in honor

who best combines high

Toxicology's Edward A. Carr Jr.
Clinical Pharmacology Award
and the DouglasS. Riggs Award.

GtLLIN

ogy course. Dr. Witebsky was the founding
chair of the Department of Microbiology.

demic Excellence, which is
presented to the second-year
student who has demonstrated
high academic achievement and

ELIZABETH BOURKE

~iaa Lia, '13, received the Depart-

standards of academic
achievement with outDARius LoGHMANEE
standing service to the
community. The second-year class chooses

The award is given to the
student achieving the highest

the recipient

average in the Fundamentals of

of past chairs of the department

}IAN LIN

Pharmacology course. Drs. Carr

Drs. james A. Gibson, Wayne ). Atwell and

Laura Ciaski, '13, received

and Riggs were chairs of the Department of

Oliver P. jones.

the Department of Pa-

Pharmacology and Toxicology.

thology's Kornel Terplan

Natalie Sbaw, '14,

received the

Award, presented to the

Department of Biochemistry's

student with the highest

Lisa Esler, '13, larn Cbaa, '13, an~ IISs
Iieber, '13, received the AstraZeneka Car-

Edward L Curvish Award, which

combined average in the

diovascular Drug Monograph Awards,

recognizes the student with the

two second-year pathology courses. Dr. Terplan

which are presented to second-year students

highest average in the two first-

LHRA C1NSK I

year biochemistry courses.

was a past chair of the department

by the Department of Pharmacology and
Toxicology. They are based on the quality
of a mono-

Timatby Par~ee, '13,

NATAUF SHA\\

graph written

'13,

ceived the Department

in the form

received the Department

of Pathology's john B.

of a package

Sheffer Award, which is

insert

Darat~y Hn~ricks,

ofMicrobiology's Ernest
Witebsky Award for

given to the second-year
student who has per-

Proficiency in Microbiology, which is given to

formed at the highest
DoROTHY

24

re-

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TIMOTHY PAROFF

LISA ESLER

Ross

RICHER

�Je1aifer NIWibilski, '14, received
the Department of Physiology
and Biophysics' Donald W.
Rennie Physiology Prize, which
is given to the student with the
highest combined average in the

l

\

two physiology courses in the
first year. Dr. Rennie was a former vice president for research at UB
and chair of the Department of Physiology

AL F R E D FRo NTE RA

SARA KAPROVE

LYNDS AY

ESME FINLAY

WILLMOTT-BARTOS

Discipline Honorary Societies:

Narab Jaaasy, '13, received the

and Biophysics.

The Association of Pathology Chairs Honor
Society awardees were Laara Ciaski, Alfred

.leaaifer Naw1bilski, '14,
aad Natalie Sbaw, '84, re-

and Esllle Fialay, all in the Class of 2003 ( Cinski

Evan Calkins Primary Care
Achievement Award, which is
given to one outstanding student in the Primary Care Summer Externship Program. Dr.
Calkins is a former chair of the

Fr11tera. Lyadsay Willmatt·lanas, Saralapme.

ceived the McGraw-Hill
Book Awards, which are
given to the two highestranking students in the
first -year curriculum.

is pictured on page 24.)

Department of Medicine.

CD

NoRAH JANosv

NATALI E SHAW

Dean's Letters of Commendation
Dean's Letters of Commendation recognize exceptional coursework. In years one and two, they are a
earn honors grades in 75 percent of required courses or achieve 75 percent of available honors pom
three, students who earn at least four honors and two high satisfactory grades are honored.
Letters in Yea

NICOLE MANN

DANIEL BAER

)EFFREY MARTI

DOROTHY HENDRICKS

CHRISTOPHER Ross1

Tooo )ANICKI

ELENA SALKOVSKY

FORESTO
CHRISTINE KERR

MEGAN MooRE

ADAM COHEN

NoRAH )ANOSY

ERIC SCHAEFER

DAVID KRAKOWSKI

CHRISTOPHER

SYED MusTAFA

DANIEL COTTER

SARA KAPROVE

DAviD ScHLESINGER

BRIAN MALM

KIMBERLY CARNEY

jENNIFER NELSON

KAMALJOT DHINGRA

jENNIFER KoRZEN

LARISSA STABINSKI

ANTHONY MATO

jENNIFER

DANIELLE DoRSANEO

THERESA Kouo

jENNIFER TRASK

CHRISTOPHER MUTTY

LISA DosSANTos

KIMBERLEY LEONARD

STEPHEN TURKOVICH

KATHLEEN

REBECCA DWYER

)IAN LIN

)ULIE VOGEL

LISA ESLER

)AMES LIN

BoBBI WAx

ANDREW SWAN

LYNDSAY WILLMOTT-

ANDREW SYMONS

OWOBILSKI

ORA CHAN
GREGORY Co NOLLY
THOMAS DuQUIN
SARA GAUGHAN
CAREN GELLIN
BRIAN GIORDANO

DIANA PRATT
ATALIE SHAW
GARRON SoLOMON

ESME FINLAY

MARA LINSCOTT

STEPHEN VARA

DAVID FINTAK

NATASHA MANES

MICHAEL

MELANIE FIORELLA

VALERIE MARCHI

ZAIR FISHKIN

CYNTHIA MARTINEZ-

CARMINE "ALEX"

l

KIT CHENG
LAURA CINSKI

)AMES BoYLE

BRENNAN

I

EZ

WEINGARTEN

DAVID FLI T

GRIECO
)ASON GUTMAN
CHRISTINA
HAVERSTOCK

Lett

.arll

APRIL BAKER
SUNIL BANSAL

CAPOLINO

BARTOS
)OYCE ZMUDA

MICHAEL WHITESIDE

HEATHER MORGANTI

SUZIE ARIYARATANA

ALFRED FRONTERA

RICHARD

LILY BELFI

BRYAN GARGA 0

AARON OLDEN

LINDA CUOMO
jENNIFER DEFAZIO
KEELY DWYER-

SHERU KANSAL

ELIZABETH BouRKE

)ULIE GAVIN

BRIAN PAGE

ERIC Ko

)AMES BOYLE

LISA GELMAN

TIMOTHY PARDEE

SANDY KOTIAH

BRANDY BRYDEN

DAVID GRAY

BRENT RISCILI

CRISTINA LAM PURl

ALBERT CHA G

HoWARD HAo

KERRYN ROCK

)ULIANE THURLOW
KAREN WEISS

Le ters in ear Ill

ANDREW FREEMAN

EWELL

O'DoNNELL

MATZKY
CHRISTOPHER

Wint e r

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Engender Health

I COLE
PERADOTTO

Christiane Northrup, MD, delivers inaugural Lawrence and Nancy Golden Lecture
hen Christiane

orthrup, MD,

When it came time to decide

began stressing the importance of

who would kick off the lectureship,

holistic health during the 1980s, it

Northrup was an easy choice for the

seemed like she was a lone voice in

Goldens. A dynamic speaker who

the wilderness. The obstetriciangynecologist remembers shutting

has hosted four popular specials on
PBS, the Ellicottville, ew York,

her office door while discussing

native, who now lives and practices

nutrition with a patient, for fear

in Maine, has received international

a colleague would hear her dispen-

acclaim for advocating that women

sing such unconventional advice.

tune in to their bodies, take charge
of their health and take it easy on

What a difference 20 years can
make. Today, mainstream news pro-

While addressing UB medical

stories about healing foods. Ameri-

students, she similarly encouraged

cans are pending billions of dollars

them to listen to their inner wis-

in alternative medicine and thera-

dom and know their limits. "We all

pies. At health clubs, yoga and Pilates

have this intuitive ability to know

are all the rage.
For her part, Northrup doesn't

what's the right thing to do for our
patients," Northrup said. "What

need to whisper behind doors anymore. In fact, so many

you need to learn is how to be good surgeons, good

people want to hear what she has to say about wellness

plumbers. You have to tie the knots right; you have to
know this body of work. But that also means that you
cannot treat every patient in an ideal way because it

and health that her first book, Women's Bodies, Women's
Wisdom, sold more than 1.2 million copies. Last year's

follow-up, The Wisdom ofMenopause, leaped to first place

takes too long. So choose one patient a week with whom

among advice books on the New York Times best-seller list

you'll interact fully, on whom you'll take a full history.

a week after it was released.

"You can be St. Francis of Assisi and pretend that

"It's really gratifying to see how things have changed,"

patient is someone you're administering to. Be a physi-

Northrup said during a September 24, 2001, lecture at the

cian in that way for one person a week who somehow

University at Buffalo School of Medicine and Biomedical

grabs your soul."

Sciences. "As far as I'm concerned, it's a miracle."

orthrup warned the group that physicians who

orthrup was the featured speaker for the inaugural

blame themselves for every patient death simply can't

Lawrence and Nancy Golden lecture on mind-body

perform effectively in the medical profession. "The

medicine. Founded in 2001, the annual lectureship aims

reason doctors get burned out is that they begin to think,

to teach medical students how the mind and body inter-

and you're taught-at least, I was-that if someone dies,

act to promote or endanger good health. A clinical professor of medicine at UB, Lawrence Golden, MD '46, was

faster than [thinking like] that."

chief of medicine and cardiology at the Millard Fillmore
Hospital, where he founded the first cardiac rehabilitation program with his \vife, ancy, a family therapist at
Child and Family Services for more than 30 years.

26

themselves.

grams and magazines abound with

lufl a l e Pb Jsician

IVi11tcr

2002

it's your fault.

othing will take the wind out of your sails

When treating patients,

orthrup told the physicians-

in-training, it's wise to consider factors outside the traditional medical model of cells and genes-factors such as
the health of a patient's marriage, her job satisfaction or

�\,

even incidents of physical abuse lingering in her past. She acknowledged
that she makes it a habit to ask patients, one simple question: "What's
going on in your life?" From the answers, she's often able to glean
important information about situations that may be compromising
her patients' health.
Although she doesn't minimize the role of molecular biology,
orthrup argues that it can't always explain the complex roots of
illness and disease. She worries that physicians too often opt for a pill's
quick fiX, yet fail to address the circumstances in a patient's environment that may be aggravating
the condition. To make matters worse, the so-called magic
bullet may even result in a new
complication-addiction.
As she spoke, orthrup reinforced her points with a slide
presentation of advertisements

Jeffrey Ross, MD '70, Delivers Terplan Lecture
The second annual Kornell. Terplan Memorial Lecture was held
October 17, 2001, in Farber Hall at the University at Buffalo
School of Medicine and Biomedical Sciences. The lecturer was
Jeffrey Ross, MD '70, chair and Cyrus Strong Merrill Professor
in the Department of Pathology and Laboratory Medicine at
Albany Medical College. He is also vice president for molecular
pathology at Millennium Pharmaceuticals of Cambridge, Massachusetts, where he served as a Scientific Fellow during 2000.
Ross's lecture was titled "From Gene to Patient: The Emergence
of Targeted Therapy and Personalized Medicine in Oncology."
The event was made possible by the generlished an endowment to fund the lecture.
Terplan's son, Martin Terplan, MD '55, assum-

for psychotropic drugs. An ad for Valium showed a woman jogging

ed a major role in creating the endowment and

down the street, her face a portrait of bliss. A Xanax ad claimed to
have unraveled the mystery of depression, pinpointing its origins at a

was in Buffalo to attend the lecture and host a

particular synaptic site in the brain.
"Depression and anxiety in the brain are highly overlapping and

r-------..1.....--

osity of the Terplan family, which has estab-

reception following it.
Kornel Terplan, MD, was professor and chair
of UB's Department of Pathology from 1933 to

they intercept," she said. "You might have some professors who think

1960 and served for many years as a pathologist

that if you get the absolute correct dose of Xanax or Prozac you will
cure your patient's life. I wish it were that easy."
orthrup added that she's not against prescribing such drugs, if
circumstances warrant it. "They all help some people. But what about
all the women who are battered in their marriage? We can't get a

at Children's Hospital of Buffalo and Buffalo General Hospital.

biochemical solution for that."

He was internationally recognized for his work in childhood
tuberculosis and brain pathology associated with chromosome
anomalies of children.
"Not only was Dr. Terplan an eminent scholar and one ofthe
leading figures at the medical school, he was also a man with
great energy and enthusiasm who was known for his personal

S

umming up her concerns, she read a quote from Max Lerner's

warmth," recalls Reid Heffner, MD, chair of UB's Department

1959 book The Unfinished Country: "What. is dangerous about
tranquilizers is that whatever peace of mmd they bnng ts a

of Pathology and Anatomical Sciences.

packaged peace of mind. When you buy a pill and buy peace of
mind, you get conditioned to cheap solutions instead of deep ones."
Since she began preaching the merits of a mind-body approach to
medicine, orthrup has contended that a woman's health is tied to
the culture she lives in. She's a harsh critic of the messages that society
sends women-destructive messages that make them feel insignificant

When the endowment to support this lecture was established by the Terplan family, the long-term goal was for UB to work
to expand it by asking former students and colleagues, as well
as those who enjoy the lectures, to join in expanding the
endowment, according to Heffner.
"We would like to be able to fully underwrite one lecturer
each year, with a visit lasting for at least one day in order to

and self-conscious. Casting an accusing glance at a lingerie ad featuring

provide an opportunity for all current medical and graduate

a gorgeous woman preparing breakfast while clad only in a bra and

students to interact with the guest lecturer," he says. "These

panties, she quipped: 'Tm sure that most women make eggs like this-

types of visits enhance the curriculum and provide students,

you know, before you go into the clinic and get going for the day."
When women- and for that matter, men- are made to believe

about exciting innovations in pathology research."

residents and practicing physicians with an opportunity to hear

that they should do it all, they're bound to think they've come up short

For information on contributing to the endowment in

at the end of the day. The cover of the health magazine Northrup

support of the annual Kornel Terplan Memorial Lecture,

used to illustrate her point read: "Be loved, think positive, eat right,

please contact Lyn Corder, associate dean for alumni affairs

stay fit, enrich your life, save the world."
"This is the new American dream," she sighed. "It makes you crazy,

and development. She may be reached by phone, toll free, at

and very stressed out."

1-877·826-3246; or by e-mail at ljcorder@buffalo.edu.

CD

W in t er

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1111111 Pbysiciaa

27

�PATHWAYS

NEws ABOUT UB's ScHooL oF
MEDICINE AND BIOMEDICAL
SCIENCES AND ITS ALUMNI,
FACULTY, STUDENTS AND STAFF

((I

HAD THE OPPORTU-

NITY TO MEET SOME
OF MY FELLOW TORCHBEARERS AT A TRAINING EVENT [IN EARLY
NOVEMBER], AND

I

WAS TRULY HUMBLED."

TURKOVICH

28

l1flal• Physician

\I' i

11

t r r

Turkovich Selected as
Olympic Torchbearer
Steve Turkovich, a third-year
student in University at Buffalo's School of Medicine and
Biomedical Sciences, was selected to be an Olympic Torchbearer for the 2002 Winter
Games in Salt Lake City, Utah.
A native of West Seneca,
ew York, Turkovich attended
Orchard Park High School
before coming to UB to complete a major in anthropology.
He was nominated for the
honor by a relative who,
among other
things, highlighted his past
involvement in
the Tar Wars
Program, which
educates elementary students about the
dangers of tobacco use, as
well as his work
with Hospice's
Life Transitions
Center, which
provides support to children
whose parents have a terminal
illness.
Turkovich was notified of
his selection on September 12,
2001, at which time he was

2 0 0 2

told he would be running Because Turkovich will be in
two-tenths of a mile at a yet- his medicine clerkship in
to-be determined location in
February, his near-future plans
unfortunately do not include
Western New York on December 31 or January 1.
attending the Olympics.
"This is an unbelievable
For more information on
honor," says Turkovich about the Olympic Torch relay and
his selection. "I had the optorchbearers, visit the 2002
portunity to meet some of Winter Olympics' website at
my fellow torchbearers at a www.saltlake2002.com and
training event [in early ov- click on Game Programs.
ember 2001], and I was truly -S. A. UNCER
humbled.
Trevisan Named
"Many of them have overInterim Dean of HRP
come much adversity in their Maurizio Trevisan, MD, prolives and are very inspira- fessor and chair of the Departtional. It's a privilege to carry ment of Social and Preventhe torch with them.
tive Medicine in the
"Too, this is the
University at Buflast time the Olymfalo School ofMedipics will be held on
icine and Biomedical
American soil for at
Sciences, has been
least the next ten
named interim dean
years," he says.
of UB's School of
"And given the
Health Related Proevents of September
fessions (HRP).
TREVISAN
11, I am especially
Trevisan succeeds
proud to represent the United Mark Krista!, PhD, professor
States in an event that stands of psychology, who has refor peace and unity."
turned to the faculty after
When asked what he hopes serving as interim dean of
his future as a physician will
HRP for 18 months. A search
hold, Turkovich says, "''d like for a permanent dean has been
to pursue a career in either under way since the death of
general pediatrics or child
Frank Brady in November
psychiatry, and perhaps also
1999, just a month after he
teach clinical medicine."
assumed the dean's position.

�l

In addition to
serving as chair of the
Department of Social
and Preventive Medicine, Trevisan is diEDGE
rector of the Center
for Preventive Medicine, part
of the Women's Health Initiative. A UB faculty member
since 1985, Trevisan's current
research is focused on cardiovascular disease epidemiology.
He earned a medical degree
from the University of aples
Medical School in Naples,
Italy, and a master's degree in
epidemiology from UB.

L EV I N E

Edge and Levine
Named Best Breast
Cancer Doctors
Two Roswell Park Cancer
Institute (RPCI) physicians
and University at Buffalo professors were named among the
top breast cancer doctors in
America in the October 2001
issue of Redbook magazine.
Stephen B. Edge, MD, chief of
breast surgery at RPCI and an
associate professor of surgery
at UB, and Ellis
Levine, MD, chief
of the medical divisions of breast and
genitourinary on cology at RPCI and
associate professor
of medicine at UB,
were among the 355
physicians cited by

the magazine's "Exclusive List: The
Breast Cancer Specialists Rated the Best
by Their Peers."
"The faculty and staff of
Roswell Park congratulate these two
outstanding physicians for the recognition given to them by
their peers through
Redbook magazine," CIAN C IO
says David C. Hohn,
MD, president and chief executive officer of RPCI. "Drs.
Edge and Levine lead a team of
caring and compassionate cancer specialists who are dedicated to giving breast cancer patients the best possible care, as
well as improving outcomes
for the disease."
Ciancio Receives Cold
Medal from AAP
Sebastian G. Ciancio, DDS,
SU Y Distinguished Service
Professor and chair of the Department of Periodontology,
has received the Gold Medal
Award from the American
Academy of Periodontology
(AAP). Ciancio received the
award- the AAP ' s highest
honor-at the group's 87th
annual meeting, held this past
fall in Philadelphia.
The Gold Medal Award is
given annually in recognition

of outstanding contributions
to the field of periodontology
and the diagnosis and treatment of periodontal diseases.
A member of the AAP for
35 years, Ciancio is a
past president of the
association, as well
as of the American
Academy of Periodontology Foundation. He is a consultant for the Journal

of Periodontology
and an editor for

Biological Therapies in Dentistry
and Periodontal Insights.
Ciancio received the AAP's
Clinical Research Award in
1996, a Special Citation in 1994
and the William]. Gies Award
in 1988.
A prolific researcher, he has
authored more than I 00 scholarly papers.
Cinsberg's Earigator
Device on the Market
The Earigator, an ear-wax
removal device invented by
Irwin Ginsberg, MD '44, adjunct clinical professor in
University at Buffalo's Department of Otolaryngology,
is currently being marketed
by SURYA Technologies of
Amherst, ew York.
Ginsberg says he identified
the need for an improved
method of removing ear wax
after observing the discomfort

that many patients endured
while undergoing the procedure, which traditionally involves irrigating with a syringe
that injects water into the external auditory canal. In addition to requiring two-people to
complete, the procedure is
time-consuming and messy,
he explains.
The Earigator, on the other
hand, delivers a large quantity
of irrigating water maintained
at 3 7 degrees Celsius and is
controlled by a pistol-grip tip
equipped with an
optically programmed trigger. A large
deflector disc uses
fiberoptics to illuminate the gently
pulsating stream of
water and the ear
canal. The proce- GINSBERG
dure can be done in
one-third the time of the
syringe method and can be
performed by a trained medical professional other than a
physician.
Currently SURYA Technologies is featuring the device
at trade shows and arranging
onsite demonstrations for audiologists, otolaryngologists,
pediatricians and hearing aid
dispensaries.
"The response to the product has been very good, and we
are quite encouraged," reports

"THE RESPONSE TO THE [£ARIGATOR] HAS BEEN VERY GOOD, AND WE ARE QUITE ENCOURAGED,"
REPORTS

RAJ

BANSAL OF SURYA TECHNOLOGIES. "WE HAD BEEN FOCUSING ON WESTERN NEW

YORK BUT NOW ARE TAKING IT NATIONWIDE."

ll' i 11 ter

2002

luffalo Physician

29

�PATHWAYS

GET
C oNNECTED. • •
the exclusive right to all PDT
compounds and technologies
discovered during the next five
years of collaboration between
Light Sciences Corporation
and the PDT Center of RPCI.
This agreement also provides
- S . A. UN G ER
Light Sciences Corporation
with a license to certain novel
Global Licensing
PDT compounds previously
Agreement for
discovered
at RPCI. In return,
Photodynamic
Therapy
RPCI will receive research
Roswell Park Cancer Institute funds, licensing fees and cer(RPCI) and Light Sciences tain milestone payments, in
Corporation have entered into addition to royalties on coman exclusive global licensing mercialized products.
and research agreement for
"Light Sciences brings a
the development of future unique perspective to PDT
Photodynamic Therapy (PDT) that may well extend its use
products.
both in cancer and
Photodynamic
other diseases," exTherapy, pioneered
plains Dougherty,
at RPCI by Thomas
director of the PDT
J. Dougherty, PhD,
Center at RPCI.
"Combined with
and colleagues, is a
several highly effectwo-step treatment
tive new photosenthat uses a light sitizers developed at
sensitive drug, called DOUGHERTY
RPCI over the past
a photosensitizer,
and visible light to destroy few years that are activated at
cancer cells in solid tumors. deep-tissue penetrating wavePDT using Photofrin, a photo- lengths, this collaboration
sensitizer developed in the promises to advance the field
PDT Center at RPCI, has been of PDT and, most importantly,
approved by the U .S. Food benefit patients," he adds.
and Drug Administration
Projects to be developed
(USFDA) and regulatory under this agreement include
agencies worldwide for the preclinical and clinical retreatment of certain types of search on several unique comcancers, including lung and pounds aimed at approval by
esophageal cancers.
health agencies worldwide,
The agreement secures for including the USFDA. CD
Light Sciences Corporation - CATHERINE D O NNELLY
Raj Bansal of SURYA Technologies. "We had been focusing on Western ew York but
now are taking it nationwide."
Eventually, the product is
expected to make its way into
the worldwide market.

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~ CIMINELLI
'
30

luflall Physician

\\' i nt er

2 00 2

•

Development Company, Inc.

�Lawrence D. Jacobs, MD, world-renowned researcher in the

an honorary doctorate from D'Youville College. He also received

treatment of multiple sclerosis who was professor and chair of

a Dean's Award from the College of Arts and Sciences at Niagara

the Department of Neurology in the University at Buffalo School

University and the Alumni Merit Award from St. Louis University.

of Medicine and Biomedical Sciences, died November 2, 2001,

Jacobs served on the board of the International Federation of

in Memorial Sloan-Kettering Cancer Center in New

Multiple Sclerosis Societies, was past president of the American

York City. He was 63.

Society of Neuroimaging anti was a founding member and former

Jacobs' ground-breaking research, geared toward
developing better treatment for relapsing multiple
sclerosis, led to the development of the drug Avonex

officer of the American Academy of Neurology Education and
Research Foundation.
Jacobs is survived by his wife, the former Pamela Ryan, a

(interferon beta·lal the most widely prescribed drug

member of the State University of New York Board of Trustees;

used to treat this debilitating form of multiple

three sons, Christopher L., Luke T. and Lawrence D. Jr., all of

sclerosis.
As early as 1981, Jacobs' research showed that
early treatment of multiple sclerosis with interferon
beta·la, a genetically engineered form of beta inter·
feron, significantly reduced the rate of progression and impact

Buffalo; two daughters, Jessica H. Enstice of Snyder, NY, and
Elizabeth R. of Buffalo; two brothers, Max of Captiva Island, FL,
and Jeremy M. of East Aurora, NY, who is chair of the UB Council;
two sisters, Michelle of Laguna Beach, CA, and Jennifer of
Phoenix; and a granddaughter.

of the disease, which often includes brain and nerve damage.
Jacobs funded his initial work privately, eventually attracting
multi-million dollar grants from the National Institutes for Health.
In 2000, the New England Journal of Medicine published the
results of a large-scale study, led by Jacobs, of the benefits of
beta·la interferon in treating multiple sclerosis, which led to the
Harvard Health Letter naming his research as one of the 10

leading health advances for 2000.
After earning his medical degree from St. Louis University
and completing his residency at Mount Sinai Hospital and School
of Medicine in New York City, Jacobs returned to his native Buf·
falo, where he began his career in medicine as an attending
physician at Millard Fillmore Hospital. He served as chief of
research at the Dent Neurological Institute from 1985 to 1989.
In 1987, he became director of the William C. Baird Multiple
Sclerosis Research Center at Buffalo General Hospital, which was
devoted to developing better treatments for the disease and excel·
lence in patient education, clinical programs and support services.
The Jacobs Neurological Institute, which he also directed, was
dedicated in memory of his parents, Genevieve and Louis.
Jacobs held the Irvin and Rosemary Smith Chair in Neurology
in the School of Medicine and Biomedical Sciences, established
in 1998 with a 51.5 million endowment from Biogen, manufac·
turer of Avonex.
He authored more than 200 publications on neurology and
served on numerous medical journal editorial boards. He was the
recipient of many awards, including the Stockton Kimball Award
from the UB School of Medicine and Biomedical Sciences, the

Gloria L. Roblin, PhD, the first non-physician to become a full
clinical professor at the University at Buffalo School of Medicine
and Biomedical Scie ces, died April25, 2001, in Millard Fillmore
Hospital. She was 76.
Born Gloria Landsman in New York City, Roblin
graduated from Barnard College at age 20 and within
two years earned a master's degree and joined the
Columbia University faculty.
She moved to Buffalo and put her career on hold
· after marrying local industrialist and civic leader
Daniel A. Roblin Jr., who died in 1986. Once her
children completed elementary school, however,
Roblin returned to UB and earned a doctorate in
psychology in two years, finishing the coursework
ROBLIN

with distinction.
During her years as a clinical professor at UB,

she pioneered the medical study of both human sexuality and
clinical hypnosis. In particular, she was credited with
engendering understanding of sexual orientation.
An animated and entertaining speaker, her lectures and
speeches drew standing-room-only audiences. In 1980, the
medical school's yearbook was dedicated to her.
Surviving are her husband, Bennett Friedman of Bradford,
PA. her son, Daniel A. Ill of Buffalo, and her daughter, Diane
Finlayson of Toronto.

Stephen B. Kelley Award from the National Multiple Sclerosis
Society of Western New York and Northwest Pennsylvania, and

r\ 1

tJ

t

t~ ...

llffaft Hysitill

31

�RESEARCH

E

W

S

$7.3 Million Crant to Study
the Effects of Periodontal
Treatment on Heart Disease
he University at Buffalo has received a $7.3 million grant from the
National Institute of Dental and
Craniofacial Research to plan and
conduct a pilot study for a clinical
trial of the impact of periodontal
disease treatment on prevention of
second heart attacks.
The three-year effort, involving five
centers, will set the stage for a definitive
clinical trial on a larger scale of the relationship between periodontal infection,
which affects 75 percent of Americans, and
cardiovascular disease.
Robert }. Genco, DDS, PhD, chair of
the Department of Oral Biology in the
School of Dental Medicine and a SUNY
Distinguished Professor, is principal investigator on the grant.
UB is leading the study, which also involves the University of North Carolina,
Boston University, Kaiser Permanente/
Oregon Health and Science University
and the University of Maryland.

DDS, PhD, SUNY Distinguished Professor and chair of the Department
of Oral Biology in the University at Buffalo School of Dental Medicine. Recently, Genco

A Potential New Weapon
Against Heart Disease
Genco says the grant "provides an opportunity to bring the basic research we have
been doing at UB on periodontal infection and its potential effect on the risk of
heart disease and stroke into the real
world of the clinic.
"If we find through this pilot study
that keeping gum disease in check appears to lessen the chances of a second
cardiovascular incident," Genco continues, "we will be justified in proposing a
large-scale clinical trial that should provide definitive answers on the relationship
between these two chronic conditions. If
the study is positive, it will give us one
more weapon in the battle against heart

32

I u f f II

0

p by sic i I D

\1 ' i

11

t

er 2 0 0 2

was named a vice provost at UB and appointed head of its new Office of Science and
Technology Transfer and Outreach, which replaces the UB Business Alliance. The new
office will strengthen the university's existing business partnerships and foster creation
of new businesses and commercialization of the university's intellectual property.

disease; however, we are a long way from
having the data necessary to suggest that
treatment of gum disease or any infection will reduce heart disease. "
The grant will allow Genco and coinvestigators to assemble a team of cardiologists, periodontists, epidemiologists,
infectious-disease specialists, biostatisticians, research nurses in periodontics and
cardiology, and data managers necessary
to carry out a full-blown periodontal intervention trial.

The Question to Be Answered
The planning period and pilot study are
intended to form the foundation for a definitive trial to answer the question "If
periodontal infection is suppressed by an
anti-infective intervention , will this result
in decreased risk of heart disease?"
"It is important to answer this question in a clear and definitive fashion before any clinical decisions are to be made
to treat periodontal disease for general
health reasons," Genco says.

�The pilot clinical trial will begin after
a nine-month planning and development
period. It will include three groups of
subjects: one that will receive antibiotic
therapy directed to suppressing the local
gum infection; a second that will receive
local therapy plus treatment with the
systemic antibiotic azithromycin; and a
third that will receive standard care.
The investigators will assess a risk
factor for heart disease, the C-reactive
protein, which also may be related to
periodontal infection.
A total of 900 persons who have periodontal disease and have had one heart
attack or are otherwise at high risk for a
cardiovascular event will be recruited for
the trial by the five centers. The pilot trial
will be used to refine the infrastructure and
to select or refine an intervention protocol
for the definitive trial, Genco says.
Growin g Evidence of a Link
Epidemiological studies conducted at VB
and elsewhere have shown an association
between various measures of poor dental
health and coronary disease, even after
accounting for other risk factors.
A 1999 study using data collected nationwide through the Third ational
Health and Nutrition Examination Survey, for example, found that people with
the most severe periodontal disease were
nearly four times more likely to have had
a heart attack than people with no periodontal disease.
Genco's research team at VB, in one
of several studies, assessed the presence
of specific oral bacteria in heart-attack
patients compared to healthy controls.
The researchers found that two periodontal bacteria (Porphyromonas gingiva/is and Bacteroides forsythus) were
associated with a 2.5 and 3.0 increase in
risk, respectively, of heart attack.
Periodontal disease is common in the
United States. Seventy-five percent of

the population suffers mild forms, while
20-30 percent has more severe forms,
according to the most recent statistics
from the national health survey.
"There is growing evidence of a relationship between infection and atherosclerosis, as well as a specific link between
periodontal infection and heart disease,"
Genco says. "Previous studies have established possible effective treatments of
periodontal disease, and it is possible
these treatments may lead to fewer subsequent myocardial events in people at
high risk for cardiovascular disease. Our
study is designed to select the periodontal
treatment with the best chance of reducing
the risk for heart disease."
Co-investigators-all from UB-are
Maurizio Trevisan, MD, professor and
chair of the Department of Social and
Preventive Medicine and interim dean of
the School of Health Related Professions; Susan Graham, MD, associate professor of medicine; Sara Grossi, DDS,
clinical assistant professor of oral biology; Joseph J. Zambon, DDS, PhD, professor of periodontics and endodontics;
and Paola Muti, MD, PhD, associate professor of social and preventive medicine.
- Lots

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Medical Student Research
Training Grant
Faculty in the University at Buffalo's
School of Medicine and Biomedical Sciences have received a five-year, $231,000
training grant from the National Institutes of Health to support summer research fellowships for medical students.
The grant will fund stipends for eight
first- and second-year medical students
to spend 10 weeks during their summer
sessions performing a mentored research
project that focuses on infectious

destination city. Call l -800-888-1170
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Wint e r

2 00 2

1111111 nysicill

33

�RESEAR

C

H

E

W

S

earc
it funds. Murphy has
had a long-standing
interest in ear and
respiratory tract infections. He holds
several patents in volving vaccines, in-

- $2 Million Crant
· Targets Ear and
Lung Infections

u

Scientists at the University at
Buffalo, the Veterans Affairs
(VA ) Medical Center in Buffalo and Roswell Park Cancer
Institute ( RPCI) have received
a 2 million program project
grant from the ational Institutes of Health to conduct research aimed at developing
vaccines to prevent ear infections in children and respiratory tract infections in adu lts
with chronic lung disease.
Timothy Murphy, MD ,
professor of medicine and
microbiology and chief of infectious diseases at UB and the
VA medical center, is principal
investigator for the four-year
grant, as well as leader of one
of the three research projects

34

luflale

Phys ician

ll'tll ter

cluding one for the
P6 protein, which he
discovered and has
been studying for 15
years. This protein is
a promising vaccine
candidate for the
prevention of recurrent ear and lung infections caused by
nonencapsulated strains of the
bacterium Haemophilus influenzae, and it is currently being
tested in early clinical trials
in humans.

collection of samples obtained
from the long-running VA
COPD study, in which 110
veterans have been followed.
Yasmin Thanava la, PhD,
cancer research scientist at
RPCI, and Anthony Campagnari, UB associate professor of
microbiology, each will direct
one of the remaining projects.
Thanavala, an immunologist who has performed innovative research in the develop-

Ge11tzke &amp;
Associates. Inc.
Registered Investment Advisor

All three projects include
studies of clinical samples
emanating from a chronic ob-

Prinrte Portfolio/
\\' ca It h \ lanagrmcnt

structive pulmonary disease
(COPD) study clinic that has
been conducted continuously
since 1994 at the VA hospital
by Murphy and Sanjay Sethi,
MD, UB associate professor
of medicine.
The project Murphy is leading will involve experiments
to determine the human antibody response to th e bacterium Moraxella catarrhalis,
which is a common cause of
ear infections in children and
of lung infections in adults
with COPD. To accomplish
this, he and his team will test a

2002

ment of vaccines for hepatitis,
wi ll study the human immune
response to specific regions of
the P6 molecule. She will introduce human lymphocytes into
mice that lack immune systems, creating an animal model
with a human immune system.
The mice will be immunized
with P6 and the researchers will
study the antibody response.
This is the "next best thing"
to immunizing people, according to Murphy, because the
mice make human antibodies.
As another part the project, researchers will collect lymphocytes from healthy donors and

Comprrhrn:,i,·r Planning
Financial. C~tale. l?etin'lltenl. Tax

Tru:,t Sc 1Yice::,
Pre&lt;odent and cro Gleon Gefltzke and
Oloef Investment StrategiSt Chris King

Concierge ScrYicr::,
l

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Tel: (716) 639·0475
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10661 Crump Road
Holland, NY 14080
Tel: (716) 537·2269
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ri\\-C.HI.I· \&lt;hi-,or
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( .t'rl ifit·&lt; I (JuidJJooks
Proft•-,-,ionnl \&lt; h i-,or-,

�from adults with COPD and
study the response of these
cells to P6.
Campagnari is a widely recognized authority in studies of
the mechanisms of infection
and the immune response to
the bacterium M. catarrhalis.
His project involves studies of
an important molecule on the
surface of the bacterium called
lipooligosaccharide, or LOS.
This molecule is critical to the
bacterium 's ability to attach to
the human mucous membranes and to cause the inflammation seen in the ears of children and the airwa ys of adults

with COPD during infection.
"Understanding the speci fie
mechanisms whereby the LOS
molecule does this is the first
step in designing novel strategies to prevent these deleterious effects of infection, " notes
Murphy. " Dr. Campagnari
will clone the genes that are
responsible for making LOS
and make mutant bacteria
with altered LOS molecules.
This will allow him to elucidate
the role of LOS in infections. "
In addition, samples from
the COPD study clinic will be
used to study the human immune response to the LOS

molecule. Campagnari also
will collaborate with Howard
Faden , MD, UB professor of
pediatrics at Children 's Hospital of Buffalo , to study
samples obtained from children with ear infections. &lt;Ii)
- L O IS B A K ER

diseases, microbiology or immunology. Twenty UB faculty
members with active, extramurall y funded research programs will serve as a pool of
mentors for the students.
Principal investigator on
the grant is Timothy F. Mur-

phy, MD, director of the Division of Infectious Diseases at
UB's School of Medicine and
Biomedical Sciences and chief
of infectious diseases at the
Department of Veterans Affairs Medical Center. Coprin cipal investigators are Stanley
Schwartz, MD, PhD, director
of UB's Division of Allergy/
Immunology and professor of
medicine, pediatrics and microbiology; and Charles M .
Severin, MD, PhD, assistant
dean for years l and 2, and associate professor of pathology
and anatomical sciences. &lt;Ii)
- S. A.

UNGE R

C'l 2002 Porsche Cars North Amenca, Inc. Porsche recommends seat belt usage and observance of all traff1c laws at all t1mes. Performance specd 1cat 1ons for companson purposes only.

a

You dream about it. You decide to get it.
Then you enter kindergarten.

The more kids you have, the more
practical it becomes.

Maybe it was the shape. Or the sound. Maybe it was so long
ago you can't remember what made you determined to
someday drive one. Meanwhile, we put the years to good use,
making the 320 horsepower 911 Carrera our best yet.

A top that glides elegantly back in seconds. A new, more
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1Vi11ter

2002

l •ffale Hysicia1

35

�RESEARCH

N

E

w

s

average amounts, but who
drink together and in their
own home, tend to be very satisfied with their marriages. We
also have found that couples in
which the husband and wife
have dramatically different
drinking patterns are often
the least satisfied with their

Impact of Alcohol
on Marriage Studied
The impact of alcohol on
marriage-for better or for
worse-is the focus of a study
being conducted by a scientist
at the University at Buffalo's
Research Institute on Addictions (RIA) under a new 1.5
million grant from the ational Institute on Alcohol Abuse
and Alcoholism.
Kenneth E. Leonard, PhD, a
clinical psychologist at RIA
who also is a research professor

Children's Health
and Polluted Fish
The Toxicology Research Center
at the University at Buffalo School
of Medicine and Biomedical Sciences will receive $1.3 million
over the next five years as a par-

"This study will

ment of Psychia-

ticipant in a new six-member

examine how

try in the School
of Medicine and
Biomedical Sciences, is studying
alcohol, the transition to mar-

children's environmental health

change and adapt
their drinking
patterns to each
other over the early

riage, and spouse
and peer influ ence on the use of alcohol.
"While it seem common
sense that drinking problems
can cause divorce, there also is
evidence that some couples
can incorporate heavy drinking into the marriage," Leon-

years of marriage."

ard says.
"Our previous research has
found that couples who drink
frequently and drink above

l alfalt Hysician

Wt11ter

pal roles in the project are James
Olson, PhD, professor of pharma-

Researchers will look at the effect

cology and toxicology, and Rich-

of eating fish from these contami-

ard Fitzpatrick, laboratory direc-

nated sources on the motor, sen-

tor of the Toxicology Research

sory and mental development of

Center.
The University of Illinois at Chi-

the refugees' children. The project
also will involve educating the

cago, Michigan State

communities on safe fishing

University, the New York

sites, safe types of fish and pre-

State Department

paration methods that reduce the

of Health and the

risk of contamination.
The Toxicology Research Cen-

University of
Texas Health

l--\.1~-::::::;;;:~:;;;:::=:~
"(f

ter will serve as the core analytical

ScienceCen-

toxicology facility for the study.

ter also are

Paul Kostyniak, PhD, director of

membersofthe

the center, will head the analytical

new consortium.

core project. Also playing princi-

-

CD

LOIS BAKER

-KATHLEEN WEAVER

in the Depart-

husbands and wives

36

marriage.
"This study," he adds, "will
examine how husbands and
wives change and adapt their
drinking patterns to each other
over the early years of marriage, and which couple-drinking patterns can have a deleterious effect on marriage." CD

important part of the diet of the
two refugee groups being studied.

research center formed to study
the effects on Laotian and Hmong
refugees of eating large quantities of contaminated Great
Lakes fish.

"I've retired my snow shovel!"
A5 a semor, l enJoy my mdependence.
That:S why the Amberleigh lifestyle IS
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snow, I have ume to spend on thincr
that I enJoy' My monthly rental lee
includes three meals a day m a
grac1ous dining room, weekly
housekeepmg, scheduled courtCS)
transportation, plus a \\ide range of
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think Amberielgh IS what you've been
lookmg for, why not call today for a
personaltour7 Call 689-4555 ... you'll
be glad you did'

The project, called the Fox
River Environmental and Diet
Study, or FRIENDS, is centered at
the University of Illinois at
Urbana-Champaign. The Fox River,
which cuts through Green Bay,

fv\onthly rent inc udes. we -oppr m•• d ore
and twc.bedrocm oporlm •nl • th _ "leo s
served dody • w ,kJy h ,,
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• emergency resp&lt; n "' •Y''' m • sc~edu ed tronspo
• exercise room • pet w1ng • guest apartments

is one of the most heavily PCB·
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Retirement living... the way you always dreamed it would be.

Lakes Basin and the single largest source of PCBs entering
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Lake Michigan make up an

2002

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For a Jtcc brochure
or personal row~
Call

(716) 689-4555

�DEVELOPMENT

N

E

w s

any Rainbows Yet to find
By Li nda J . Cor de r , PhD. CFRE
the
rainbow ended at Farber Hall. There had been a run of
gray days, literally and figuratively, so the ephemeral
colors leading right to our school seemed to be a good
sign, and I spent the remainder of the semester looking
for rainbows.
New York was hit hard by the tragedies in September, especially those families who were directly affected
by terrorists' actions. Budgets, already tight, became more
tentative as legislators struggled to decide among competing priorities, and donors dealt with myriad requests
under the shadow of a volatile stock market. Within the
school, course coordinators, administrators and students met in different
types of ad hoc groups to adjust to
change and devise plans for finding
resources that make our respective
responsibilities possible.
You are likely aware of some of our
efforts. The first full alumni annual
appeal was mailed. We are stili receiving responses from graduates of the
school's many programs. Class chairs for spring medical
reunions are working to increase class gifts. The Pathology
and Anatomical Sciences Department held the second
annual Terplan Lecture and added several thousand
dollars to that endowment. A bequest, "on the books"
for more than twenty years, came in, half designated
for scholarships, the remainder for a radiology lecture
fund and seed money for radiation research. The school
also received proceeds from a charitable trust, again
designated for scholarships. As a community, we celebrated the life of, and grieved for, Dr. Lawrence Jacobs, chair
of neurology, who died "too soon," yet who accomplished much through his research on multiple sclerosis.
A dedicated faculty and staff group began plans to
augment the Clinical Skills Development Fund, an extremely important account for those teaching students
how best to communicate with patients. Family Medicine, the first department to form an advisory board

and hire a development officer, launched a drive to increase their departmental endowment, with an initial
goal of $250,000.
Members of the Medical Emeritus Faculty Group
met regularly throughout the year, and the Medical
Alumni Association has extended its membership to them.
Dean Bernardino and administrative staff joined those in
comparable positions for the Asand sllllnts .et illlffmlt
sociation of American Medical
~
Colleges' fall meeting in Washington D.C. These gatherings
llljlst t1cllaiCIIIIIIIInisl
provide a perspective on where
the school is now, relative to peer
institutions and to its own progress compared with a year, or
res,.sillilities jiiSSillle.
several years, before.
My personal benchmark is the
beginning of the campaign, summer of 1996, essentially
the same time I returned to UB. That year, Buffalo
Physician had an interim editor. This year, the magazine
received highest honors from AAMC's Group on
Institutional Advancement. In 1996, we had 169 members in the James Platt White Society and raised slightly
over a million dollars from alumni and friends. Today,
we have commitments for 85 percent of the school's
campaign goal of $50 million. We have several new
endowed lectures, many more scholarships, nearly 300
White Society members, a few endowed chairs and
many planned gifts in the pipeline. We have an active
Dean's Advisory Council extending the network of
volunteers and donors-which is fortunate because, in
one sense, we have barely begun. Those meetings come
around with startling frequency and there are many
rainbows yet to find.
4D

....,...

Linda (Lyn) Corder, PhD, is associate dean for alumni
affairs and development. She can be contacted at
1-877-826-3246, or via e-mail at ljcorder@buffalo.edu.

ll'111ter

2002

II

If a II Pb J sic i a I

37

�STUDENT

C

L

U

M

Wisdom Shared and Gained

B v
SvETLANA

Moving from Butler Auditorium to the hospital-the third·year experience

BLITSHTEY
CLASS

0

or

NEVER KNEW what "CCIII" meant
until a year ago, when as a third-year
medical student I left the safe familiarity
of Butler Auditorium and entered the
unfamiliar surroundings of the hospital.
Suddenly, an intricate and exciting world of clinical practice unfolded before me
in a way that had
been impossible
to anticipate in
the sheltered environment of a
classroom. It was
in the hospital,
hidden in the
white coat, blue
scrubs and progress notes, that I
found the meaning of CCIII"clinical clerk of
the third year"and came to the
realization that I
occupied the lowest rank in the hierarchy of hospital titles.
After two years of basic science, many students
welcomed the third year, while others feared the unknown. Regardless of how anyone felt, we all knew
that what lay ahead was printed on a schedule:
family medicine, obstetrics/gynecology, medicine,
psychiatry, pediatrics and surgery.
Looking back, I wonder who could have predicted
that becoming a CCIII would turn out to be one of
the most memorable and fulfilling experiences in
medical education?

38

luffall Physician

1\' i

11 t

e r

2 0 0 2

Fam· · edicine: Deep Re elation

I

opened the door to the room where a patient was
waiting anxiously for the doctor. She had been
coughing, running a fever and feeling so fatigued
that washing dishes had become an ordeal in endurance. She was expecting the doctor to uncover the
mystery of her bothersome symptoms and make her
feel "all better." This expectation changed abruptly
when she noticed a short white coat and the phrase
"medical student" in the formal introduction.
"How much do you know?" she asked suspiciously.
"Certainly not enough to feel confident," I thought
to myself.
With her permission, I dared to continue asking
numerous questions and to complete a physical exam.
After analyzing her history and physical findings, I
suddenly realized that I was about to embark on a
crucial milestone in my medical student career: my
first diagnosis, a case of pneumonia.
At last, the two years of basic sciences and what
had, at the time, seemed like useless memorization of
details were merging into a whole. The knowledge of
anatomy, physiology and pathology of the respiratory
system and the knowledge of microbiology and pharmacology related to pathogenesis and treatment of
pneumonia were now necessary to help this patient.
And so !left the room with a sense of deep revelation:
I was ready.

Obs et ics and Gynecolor'" Wha• oTextbook Can Teach

T

he evenly scheduled outpatient appointments of
the family medicine practice were followed by the
fast pace of obstetrics and gynecology. For the first
time, I was spending more than 24 consecutive hours
working in the hospital, realizing that in obstetrics and
gynecology, night no longer signified a time for relaxation and sleep. The distinction between day and night
was forever lost on the floors oflabor and delivery.
It was there, however, that I first witnessed something beautiful, something no textbook was capable of
teaching me: the birth of a child. I will never forget

�standing anxiously by a woman whom I had known
only since the beginning of my shift, surrounded by
her family, and by nurses and residents. I, the CClll,
was allowed, under the watchful eyes of the residents,
to deliver a baby into this world. As I tried to hold on
desperately to the small slippery body of the newborn
taking its first breath, I thought to myself what a
privilege it was to take part in the sanctity of this

Medicine: An Introduction to the End of Life

I

have wondered relentlessly what it takes to become a
good physician. If I memorize the names of every
muscle and every nerve, if I understand the pathology of every disease, if I learn every pathogen and
every medication, will I then have acquired sufficient

knowledge to become a physician?
While my medicine clerkship taught me the basic
skills of reading EKGs, interpreting laboratory tests
and recognizing emergency states, working with patients taught me the meaning of the phrase "my patient." For the first time, I felt a tremendous sense of
responsibility, obligation and loyalty to those chosen
among many on the ward as "the best teaching cases."
I knew their every complaint, abnormal physical
finding and lab value, their daily vitals and pending
diagnostic procedures. I was introduced to their
family members, was made aware of their occupation
and hobbies, and was contacted by their numerous
care providers about the status of their condition.
One of my patients, a 50-year-old woman with
stage IV adenocarcinoma of the lungs, was planning
to undergo an experimental treatment at Roswell
Park Cancer Institute. Every day she would tell me
"''m a little better today," even though her condition
was obviously deteriorating.
Then one day during grand rounds, she could no
longer contain her emotions and began crying. She
knew as well as we did that she would not live to
undergo the experimental therapy. Struggling to carry
on a conversation, she described her feelings of desperation, hopelessness and fear of impending death.
She was already grieving for herself, for her children
and for her seven-year-old granddaughter, whose
get-well picture posted by the bed served as a subtle
reminder of a future stripped of watching her grow.

I ;\lE;\lORIZE 1 HI.:.
I

With her permis·

patient is gone."

sion.l dared to
continue asking

Psychiatry. Compassion and Complex Ques ions
ompassion in medicine is viewed not as a trait of
character; it is emphasized as an essential element
that defines the physician as a healer. Compassion
is naturally felt toward a patient battling cancer or a
severe physical disease. However, to feel this emotion
for those suffering from a mental illness requires a willingness to look past the disease, as well as an encounter
that may influence how one views mental illness.
For me, this encounter occurred when I was asked
to evaluate a 50-year-old man with chronic schizophrenia who was accompanied by his sister. Her concern was that "he just wasn' t himself lately": He acted
confused and lethargic and appeared physically ill.
Although his presentation was less than typical, he
exhibited several signs and symptoms suggestive of
acute exacerbation of schizophrenia. As a result, he
was admitted to the psychiatric unit and placed temporarily in the isolation room.
While I tried to convince myself that my limited
experience in psychiatry precluded disagreements with
the higher authorities, 1felt perplexed. There were certain aspects in the history and presentation of this
patient that were inconsistent with a diagnosis of
schizophrenia. Could it be that the etiology of his
symptoms were rooted in a different disease? I wondered. The answer came with the results of the routine laboratory tests taken upon admission, which,
fortunately, I decided to check before leaving the
hospital. Printed in bold on the computer screen
with the letter "C'' attached for "critical'' was a blood
sugar value ten times higher than normal.
Instantly, the diagnosis changed from acute exacerbation of schizophrenia to a life- threatening
complication from undiagnosed and untreated
diabetes mellitus.
While the patient was being transported to the
intensive care unit for treatment, a psychiatrist
on the ward approached me. H e thanked me for

A;\lES oF J:\ ER\ J\IuSCLF A. o I-.VER\ • ~::RVE, Ir

PATHOLOGY OF EVERY DISEASF, IF
\\'ILL

her family.
The next morning I was approached by one of the
nurses, and for the first time I heard the words "Your

C

family's happiest occasion!

IF

I later witnessed the final hours of her life as she
gasped for air, trying to maintain her strength for

I

I

u. · o~::Rs rA

numerous questions
and to complete a
physical exam. After
analyzing her history
and physical
findings. I suddenly
realized that I was
about to embark
on acrucial
milestone in my
medical student
career: my first
diagnosis. acase
of pneumonia.

n 1 HE

lEAR.' bYFRY PATHOGL' A. 'D EVERY ;\1EDICAriO, ,

THE.' HAVE ACQUIRED SUFFICIE. ' T K. ' 0\\'LFDGE TO BEC0:\1£ A PHYSIUA. •?

\\' irrter

2002

luffalt Pbysiciaa

39

�STUDENT

COLUMN

calling attention to the problem, mentioning that
"the patient's life was saved" because I checked his
lab results.
Although I felt honored by his words, I did not feel
proud. If this man had lost his life to diabetic coma,
would it be because he also had a mental illness? Who
would be to blame for his death? The psychiatrist whose
diagnosis was confounded by the past psychiatric history? The primary care physician who
never addressed the problem of hyperglycemia,
IF YOU ARE A STUDENT
although it had been demonstrated several
OR RESIDENT INTERESTED
times in the past? Or was it the patient's fault
IN CONTRIBUTI G TO
for
being noncompliant with keeping appointTHIS COLUMN , E - MAIL
BP - NOTES@BUFFALO. EDU
ments and taking medications, for being unTO SUGGEST A TOPIC.
able to express or comprehend the nature of
his physical symptoms, for being apathetic to
his health because he suffered from a mental illness?
As I looked at the patients through the window of
the locked doors on the psychiatric ward, I thought of
others who, by the very nature of their illnesses, are
incapable of being actively involved in their healthcare. All they can do is trust the people in white coats
and hope that they can find the right treatment and
have some compassion for their souls.

Your Turn?

Pediatrics: No Need for aStethoscope

A

s we walked through the long hospital corridors
during morning rounds, I glanced at a nearby bed
where a 15-year-old girl had just received a diagnosis of insulin-dependent diabetes mellitus. She sat
alone in her room crying.
As the team of residents and students proceeded to
discuss her case- presented with an admirable degree
of accuracy by a pediatric intern- the verdict was
confirmed: a classic manifestation of diabetes. The
treatment plan was simple and concise: administer
insulin, check blood glucose and urine ketones, enroll
in the diabetes teaching program and begin her on a
diabetic diet.
" othing exciting," the senior resident said, "just
a typical case of new-onset diabetes." The team then
moved to the next room where another case was
waiting to be discussed.
At the end of the official rounds, I decided to visit
the girl. She had stopped crying and was looking out
of the window, perplexed. She told me she dreamt
of becoming a dancer and had been taking dance
lessons since she was five. "What will my life be like?"
she wondered aloud, expecting a reply. "Will I ever
become a dancer, now that I have this disease?"

40

IDIIIII rhysiciaa

II'

1 11

re r

2 0 0 2

As I thought of my response, I began to realize the
complexity of my situation. This girl needed comfort,
support and guidance. She was not interested in hearing the pathophysiology of diabetes, or the plan of
treatment outlined in her chart. or was she interested in the statistics of long-term complications, or the
benefits of tight glucose control. She just wanted to
hear from me that she will be all right; that despite
the daily insulin injections and glucose checks, despite multiple visits to doctors, emergency rooms,
and even intensive care units, she will be able to reach
for her dreams and lead the life she desired to have.
I sat down next to her, listened to her and reassured her, and for that I did not need a stethoscope.

Surgery: AFascinating and Intimidating Close
here is something mysterious about the way lights
shine on the operating table and the way people
' dressed in blue gowns and masks work diligently
in an atmosphere of precision governed by concrete
commands. The profession of surgery- and the
demands imposed on those who dare to join itboth fascinates and intimidates.
Surgery is the clerkship concluding the yearlong
journey as CCIII. Its completion brings us to the
finish line of the third year and grants us the higher
status of CCIV.
Six clerkships ago, the third year of medical school
seemed as unattainable as a mountain that I had to
climb before reaching the next destination. Looking
back at the accomplishment, the height of the
mountain was merely a product of heightened
anticipation. Living it day by day, week by week,
clerkship by clerkship was nevertheless difficult and,
at times, overwhelming, but a small price to pay
given the rewards.
ow another class of students joins the ranks of
CCI lis, wondering whether the third year will be a
positive experience. Like all of us, they will be immersed in the details of rotations, hospitals, grading
and exams, while becoming oblivious to the insignificance of each in shaping an overall experience.
As I am nearing the completion of the year I
realize, in retrospect, that the experience was about
more than an education in the clinical practice of
medicine and how to function in it. It was also about
lessons learned from the lives of the patients, wisdom
shared by those who care for them every day, and
knowledge gained as a medical student and, above
all, as a person.
CD

�Mark your calendars

Sherman Waldman. MD '57

Saturday, April 27.

Fo~

more information, call the Medical

We're all still here! Carpe diem! We should all
enjoy each other while we can. Please consider
a glorious 45th reunion.

Alumni Association at (7161 829-2778.
The reunion classes are 1947,
Sebastian S. Fasanello. Sr. MD'&amp;2

1972, 1977, 1982,

God bless America. We must maintain our
traditions. I'm looking forward to seeing you
in April.

James F. Phillips. MD

·.n

Dear Classmate, I am chairing this year's 55th
reunion for our class. Please attend. The dinner
will be held at the best restaurant in town: my
house at 106 Depew AYenue, with Western New
Yoril's best chef, my wife, Marcella.

Thomas P. O'Connor. MD '&amp;7
Congregate and celebrate 35 years of the
finest profession on earth.
Donald (. Miller. MD '&amp;7
The face of medicine has changed drastically

since 1967. Has yours? Let's get together and
share war stories.

Robert I. Baumler. MD "52
There haYe been a lot of changes in medicine
during the past half century. Come to our
50-year reunion and let us fill each other In
on what has been going on with us and
medicine during those years.

Linda I. lam. MD "72
Thirty years! Let's get together to celebrate,
reminisce and renew friendships.

Ileal W. Fuhr. MD '52
Start making your plans now to join those of
us who remain for our sr medical school
reunion. So much has happened to all of us
since graduation. Come and bring us up to
date oa your life in and out of medicine!

Gregory (. Young. MD '77
Try to make every effort to join us as we
celebrate the 'Silver AnniYersary' of our grad·
uation from medical school. Come back and
see how UB has changed!

H • n t e r

2002

I 1 I I I I I P' 1 1 i C i 1 I

41

�Which can
you afford
to waste?
FEATURES

BENEFITS

• Electronic submission of all
major insurance claims

• Increase your accounts
receivable turnover

• Follow-up of all unpaid claims
and open patient accounts

• Improve collection ratio and
reduce bad debts

• Advisement on and assistance
with insurance carriers and
government regulations

• Optimize revenue through
proper monitoring of charge
master

• Choice of processing
options including on-line
or full-service

• Eliminate costs associated
with computer software and
maintenance

• Easy start-up or conversion
from present billing system

• Transition smoothly and quickly
while maintaining cash flow

• Appointment scheduling
software available on request

• Improve office efficiency and
patient satisfaction

• Expertise on existing and new • Assure your patients' rights are
corporate compliance guidelines protected
• Practice management with
• Gain peace of mind from
professionally trained staff and
knowing that your finances are
experienced C.P.A.'s
being managed optimally

Thomas A. Maher, C.P.A.
President

50 Alcona Avenue

MEDICAL B ILLING
S PECIALISTS

Amherst, NY 14226
Tel: (716) 834-1191
Fax: (716) 834-1382

e-mail: pbs50@aol.com

�Dear Fellow Alumni,
~e

winds of change continue to blow through our medical school. I see these changes as

signs of positive growth, and not just change for the sake of change.
Following the membership vote on Spring Clinical Day, the Medical Alumni Association
(MAA ) is now welcoming as members emeritus faculty, PhD graduates, residents of our affiliated
teaching hospitals and postdoctoral fellows. These additions will both broaden and strengthen
the interests of the association.
Dean Bernardino decided that the informal working relationship between the
school's offices of Alumni Affairs and Development should be formalized. Thus, late in
the semester, we welcomed Mary Glenn to her first MAA board meeting in her new
official role as director of constituency relations. In this capacity, Mary will serve as the
school's liaison with our association.
Another significant change in our association is the departure of

ancy Druar on

December 31, 2001. As most of you know, Nancy was secretary in the MAA's office for the past 21
years and was responsible for coordinating its day-to-day operations. In addition, she was instrumental in planning the school 's annual Spring Clinical Day and Reunion Weekend.

ancy's

presence and singular competence will be missed, and we wish her all the best.
As we incorporate these and other changes, our association will stay true to its goal of initiating
and supporting social and educational projects related to the school. These projects will no doubt
be enhanced by the increased involvement of Lyn Corder, whom Dean Bernardino has named
associate dean for development and alumni affairs. We welcome Lyn's interaction with all alumni
and know that the merger of these two offices within our school be a "work in progress" throughout this next year.
In September, the past presidents of the MAA gathered to toast our newest Distinguished
Alumnus, Marshall Lichtman, MD '60. We congratulate Dr. Lichtman on receipt of this award and
invite you to read more about his remarkable career and accomplishments on page 17 of this issue
of Buffalo Physician.
Also this past fall, the Reunion Class Chairs met for dinner to continue the planning for reunions that will be held in conjunction with Spring Clinical Day, April27, 2002. The program will
take on a historical flavor this year, with the theme "Presidential Assassinations in the 20th Century."
jack Fisher, MD '62, will deliver the Stockton Kimball Address.
Finally, I continue to ask for your support of our alma mater through your interest, time,

jOH N j. BODKIN!! ,

MD

'7 6

President, Medical Al11mni Association

�C

L

A

1940s
Maynard Mires. MD ·46,

Georgetown, DE, Preventive Medicine, writes: "!
am now retired. I have

N

0

T

E

Herbert Pirson. MD '46.

Orchard Park, NY, Diagnostic Radiology, writes:
"I am retired. My favorite
memory was graduation." E-mail address is
hsp-ecp@ worldnet.
att.net.

Daniel A. Phillips. MD '51.

1950s
Carl R. Conrad. MD '51,

Clarence, NY, Internal
Medicine, writes:"! will
never forget my first day
with Dr. 0. P. jones."
E-mail address is
carldocc@cs.com.

, Gen-

Williamsville, Y, Radiology, writes: "My wife,

having fun with special

Leslie, and I have five
grown children. Who

fond memories of the old
Medical School at 24

with Harold Levy and
Ross lmburgio in the old

High Street, where the
worn steps, the antiquated

amphitheater on
High Street."

fixtures and the memorials on the walls reminded
me that we are all part of
an ancient and honorable

could forget Doc
Leonard's messages to
the graduates?"

Alvin Volkman, MD '51,

Me Cutcheon.

Greenville, NC, Pathology, writes:"! have so
many favorite memories

MD'56.

of medical school. Physical diagnosis provided
our first clinical experience, but my group was
not satisfying our instruc-

tor Dr. john Boylan. He
demanded more than we
seemed capable of doing.
Finally, we got it all to-

am retired
from a pri-

McCuTCHEON

vate practice in Michi-

1960s

ting pretty smart.' We
were on our way to being

Long Beach, CA, OBI
G
, writes:"! am chief

doctors." E-mail address
is alphavic@earthlink.net.

of staff at Kaiser
Permanente Medical
Center in Anaheim, CA.

Mark A. Dentinger, MD '56,

Carmichael, CA, writes:
"!am retired. When I

My favorite memory of
medical school was carrying anatomic specimens

think of medical school,
I think fondly of the

from Buffalo General
Hospital to the medical

original school on
High Street."

school in the trunk of my
car in metal pails. I always
feared I would

Daphne, AL,
Otolaryngology, writes:"!

and kidneys
thrown across
the roadway."

am on the
GACEK

2002

Kenneth E. Bell. MD '61.

be in an accident with
multiple livers

MD'56,

IV1111er

gan. Friends can
e-mail me at wrenwood@
webtv.net."

gether, and Dr. Boylan
said in his slow stutter,
'You gentlemen are get-

Richard Gacek.

l uflale Physician

Pittsboro,
C, Internal
Medicine,
writes:" I

assnotes

tradition. My wife, Ruth,
and I are pictured here
with our family."

44

ries of medical school include the old building on
High Street and "Doc"
Leonard.
Sue A.

Eugene Leslie, MD '51,

eral Surgery, writes: "My
favorite memories include
friends, and shooting dice

Danny Cordova and Bob
Burke." E-mail address is

hospital staff at the University of South Alabama.
My wife, Elaine, and I
have four grown children. My favorite memo-

madap@prodigy.net.

Fred Schwarz. MD' 46,

Williamsville,

Reno,
, Orthopaedic
Surgery, writes: "I am retired. My favorite memories include my marriage
to Mary Ann in 1949, the
good friends like the late

�Harold Brody. MD '61, PhD.

Wayne P. Fricke. MD '66,

Brody's late wife, Anne,
was recently honored as
one of 100 outstanding
women in the history of
Western ew York. A
stone was placed on the
Women's Walkway-

Olcott, Y, Orthopedic
Surgery, writes: "I am
retired and enjoying life."
E-mail address is
frickes@attglobal.net.

located at the HSBC
Arena and the Waterfront-to recognize her
work in helping to establish the International
Committee of the
Women 's Club of the
State University of ew
York at Buffalo. This
committee has helped
students, faculty, and
families to adjust to living in the United States.
Anne Brody also pioneered in establishing the
Adult Day Care Program
at the Amherst Center for
Senior Services.

Marino, CA, Hematology/Oncology, writes: "!
am on the faculty of the
University of Southern

James R. Markello, MD '61,

Greenville, C, Pediatrics, writes: "I am retired.
One of my favorite
memories is the evaluation session at the home
of Mitchell Rubin, MD,
professor and chair of
pediatrics." E-mail address is munmark@
earthlink.net.
Thomas W. Bradley, MD '66,

Tonawanda, Y, Family
Practice, writes: "Retired
August 1, 1999." E-mail
address is tomjan1936@
aol.com.

Cary Presant. MD '66, San

California School of
Medicine as professor of
Clinical Medicine and
Oncology. One of my
most vivid memories was
being tested by 0. P
jones in gross anatomy
on Saturday morning,
and I did not have many
parties on Friday nights
during that course."

1970s
Jerald A. Bovino. MD '71,

Aspen, CO, Ophthalmology, writes:
"!remember Saturday
morning anatomy questions from 0. P. jones;
Dr. Megahed's kindness
and teaching generosity;
my good fortune in having wonderful classmates;
our great parties to music
of the Beatles (Sergeant
Pepper's Lonely Hearts
Club Ba11d)."
Scott A. Kirsch, MD '71,

the people in my class,
but most of all the UB
campus, which is where
I met my wife."
Richard A. Manch. MD '71.

Phoenix, AZ, Internal
Medicine, writes: "I am
on the staff at the University of Arizona College
of Medicine and the
Good Samaritan Regional Medical Center.
Fondest memories are
gross anatomy lab with
Robby Kaufman, Henry
Milgrom, Mike Armani."

1980s
Shirley A. Anain, MD '85, has

been elected president of
the medical staff at Sisters
of Charity Hospital, part
of the Catholic Health
System, in Buffalo, NY.
Anain has been a member

of the hospital's medical

Young B. Huh, MD '89,

staff since 1992. She com-

writes: "! completed a

pleted her residency in
general surgery and plastic surgery at the Cleveland Clinic Foundation
and a fellowship in plastic

gastroenterology and
hepatology fellowship in
1996 at the University of
Pittsburgh Medical Cen-

surgery at the Hospital for
Sick Children in Toronto,
Canada. She will serve a
one-year term.
Mitch lublin. MD '88, and
Mary Davitt, MD '88. re-

cently moved back to
Pittsburgh, PA. Mitch is
chief of ultrasound at
University of Pittsburgh
Medical Center in the
Department of Radiology. Mary plans to return to practicing general pediatrics soon.
E-mail address is:
tublindavitt@msn.com.

ter. I have just joined
Gastroenterology Associates, P.C., in Quad Cities,
!A. My wife, Veronica,
and I have two children:
Christopher and
Hannah." E-mail is
kimhuh@aol.com.

1990s
Deb (Delozier) D'Souza and
John DeSouza. MD '94,

write: "We recently celebrated the birth of our
second child, john joseph,
on june 12, 2001. His
older sister, Irene, is four.
We also recently moved to
Toledo, OH, where john is
practicing neuroradiology,
and I plan to practice OBI

Commack, Y, Family
Practice, writes: "My favorite memories include

GYN.
Chris Wood, MD '94. writes:
"! recently married julie
Marz, an architect. We're
living in a suburb of Chicago and I'm practicing
ophthalmology."
E-mail address is
fenny90@hotmail.com.

E-mai

CD

RICHARD MAN CH AND fAMILY.

Wi11ter

2002

l ulfall Physician

45

�A

t last year's Spring Clinical Day and Reunion Weekend, we decided to have a little fun with the Class of 1976, which was
celebrating its 25th reunion. In addition to asking class member to provide us with an update on their families and careers, we also
requested that they have their pictures taken.
Little did they know that we also had managed to lay our hands on a 1976 issue of Iris, as evidenced below!
\I ~

R Y

G

L E .• S

D I R l

C T 0

R

0 F

C 0

"

ST I

C Y

R E L A

I 0

S S

0

F I C E

0 F

\I

E D I C A L

6, Dayton, Ohio. Chris is certified in internal
18a
top
medicine and gastroenterology and is chief of medicine at Dayton VA Medical
Center. Susan is a consultant in allergy and respiratory medicine. They have
two children, Christian and Andrew.
Ch

John Bodkin, MD '76, Williamsville, NY, family medicine. Bodkin is the president of Highgate
Medical Group and president of the UB Medical Alumni Association. He and his wife,
Maria, have four boys, Jack, Michael, Ryan and Andrew.

athl n (Can ell) c er an D '76, Bethesda, MD, child psychiatry. Ackerman and her
husband, Ronald, have two children, Elizabeth and Jeffrey. Kathleen writes: "My favorite
memory of UB is graduating and seeing my father-an MD who graduated from UB's
School of Medicine-just beaming." E-mail address is drwireman@aol.com.

Christopher Brandy, MD '76, Morristown,

Y, general surgery. Brandy and his wife, Linda,
have three children, John, Brian and Kathryn. Friends can e-mail him at curtieb@giseo.net.

GreggB o man, MD 76, Glenwood, NY, medical management, pediatrics. Broffman is a

member of the governing board of the Medical Alumni Association. He and his wife,
Denise, have three children, Lauren, Andi and Jake. Gregg writes: "One of my favorite
memories of UB is time spent with friends at Don George's family cabin in North Java."
E-mail address is lbroffman@aol.com.
Paul B. Cotter Jr.. MD '76, Cohasser, MA, ophthalmology, writes: "Who can forget Dan Wild's

bachelor party." Paul and his wife, Margaret, have three children,
Paul. E-mail address is pbcotter@hotmail.com.

lndr w artin Gage, MD. '76, Williamsville,

athaniel, John and

Y, general and vascular surgeon. Gage is director of the Noninvasive Diagnostic Vascular Lab in Williamsville, NY. He is married to
Mary M. Burke.

•6

l1ffal• Pbysici11

\V

I II t

e r

2 0 0 2

A

L U ~~

�(married to Patrick Hayes), Dublin, OH, internal medicine, writes:
"My favorite memories include study dates with Pat, lunches with special friends at the
'Tiffin Room,' and movie parties at Grant Golden's." E-mail address is karen.glasgow@
mailcity.com.
Kare

Patrick R. Hayes MD '76 Dublin, OH, emergency medicine, writes: "One of my favorite

memories is meeting my future wife in gross anatomy!" Patrick and Karen have a son,
Gavin. E-mail address is pathayes@mailcity.com.

r
S
Buffalo, NY, diagnostic radiology. Golden is married to Deborah
Goldman, and they have three children, Holly, Geoffrey, and Margaret Curtis. Golden is on
the hospital staff St. Joseph's. E-mail address is old-chestnut@hotmail.com.

Donald Geor e. MD '76 Jacksonville, FL, pediatrics. George is chief pediatric/nutrition at
Nemours Children's Clinic. He and his wife, Linda, have four children, Sarah, Katherine,
Christopher, Elizabeth. E-mail address is dgeorge@mediaone.net.

n M.levitt, MD'
Nashua, H, dermatology. Levitt and his wife, Deborah, have
been very busy with their five children, Michelle, David, Tammy, Stephen and Scott. He is
in private practice in New Hampshire.
Step

ShinY liongMD 76. Anaheim Hills, CA, internal medicine. Liong works in Rancho

Cucamonga as a clinical physiatrist.

Pa

· 6. Olean, NY, surgery. Schwach and his wife, Barb, have three children,
Davis, Rebecca and Catherine. E-mail address is docschwach@yahoo.com.

Michael Smith. MD, '76. Reidsville, NC, family practice. Smith works in a

a val Hospital in

Camp LeJeune in Jacksonville.

Laszlo lomas he , D' 6, Cleveland, OH, ophthalmology. Tomaschek works in Parma, OH,

with his wife, Susanne.

Linda Wild MD 76. Buffalo, Y, pathology. Linda Wild is an associate professor of
clinical pathology at UB's School of Medicine and Biomedical Sciences. E-mail
address is wil@buffalo.edu. Linda's husband, Dan Wild, MD '76, is an orthopaedic
surgeon in private practice in Buffalo. They have two children, both of whom
are in college, Katherine (Katey) and Michael. 4D

Wi11ter

2002

l uff1le Physiciu

47

�WINTER

Kenneth M.
Alford, MD '37
Kenneth
Alford, MD '37, a
prominent member of the
Buffalo medical community
and a decorated Army veteran, died October 26, 2001,
in his Buffalo home after a
long illness. He was 89.
A Buffalo native, Alford
attended Lafayette High
School, where he was an AllHigh basketball playerfor two
years. Following graduation,
he attended Colgate University, where he also played
basketball. After college, he
returned to Buffalo to study
medicine at the University of
Buffalo, graduating in 1937.
Alford interned at Buffalo
General Hospital and the
Hospital for Sick Children in
Toronto, where, from 1939to
1940, he was chief resident in

to 1982 and a fellow in adolescent medicine at Harvard
Medical School and Boston
Children's Hospital in 1971
and 1972. He served as
trustee of CHOB from 1979 to
1993 and as a director of the
Cummings Foundation from
1975 to 1997.
Alford is survived by his
wife of 61 years, the former
Joan Wendt; a son, David H.
of Durango, CO; a daughter,
Anne Surdam of Buffalo; four
grandchildren; and a greatgrandchild.

FrankT.
Riforgiato,
MD'39
Fran T. Rifor&amp; ato, MD '39,
died unexpectedly October 26,

pediatrics. During that time
he was also an instructor in
pediatrics at the University of

2001, in Sisters Hospital. He

Toronto Medical School.
A World War II Army veteran, Alford served five years

medicine on Buffalo's West
Side for 46 years, was born In
Buffalo in 1913 and attended elementary schools in the
city. He attended Canisius
High School, graduating in
1931, and then went on to
Canisius College, earning a
bachelor's degree in 1935.
Following graduation
from the then-University of
Buffalo Medical School in
1939, Riforgiato interned at
Sisters Hospital and com-

in the 4th Medical Battalion.
On D-Day, he was part of the
landing force on Utah Beach
and served as commanding
officer at the clearing station
hospital, caring for and evacuating the wounded soldiers.
For his efforts, he was awarded
the Bronze Star.
Following the war, Alford
joined the pediatric medical
staff at Children's Hospital
of Buffalo (CHOBI, where he
was attending pediatrician
from 1977 to 1982. He also
was a member of the pediatric staff at Millard Fillmore
and Buffalo General hospitals. At Buffalo General, he
served as chief pediatrician
from 1950 to 1977.

48

Alford was clinical professor of pediatrics at the University at Buffalo from 1973

lllllll Pbysicill

was 87.
Riforgiato, who practiced

pleted his medical residency
at the former E.J. Meyer
Memorial Hospital in 1941.
During World War II,
Riforgiato served in the Army,
rising to the rank of captain.
He was stationed in Surinam,
South America, from 1941 to
1943, and also was based at
Camp Butner in North Carolina and hospitals and clinics

\\ ' 1 11

t

e r

2 0 0 2

in Kansas, including the
Menninger Clinic.
After returning to Buffalo, Riforgiato practiced
general family medicine for
46 years on the lower West
Side of the city, retiring just
a few years ago.
"He probably delivered
about half the babies in Buffalo during the baby boom,"
says his son Francis.
Besides his wife of 60
years, the former Mary Cecina
Gallo, survivors include two
daughters, Margaret Mary
Rumunno of Conway, NH, and
Mary Frances Nagel of
Gilmanton, NH; three sons,
Leonard of Miami, Philip of
Eggertsville and Francis of
the Town of Tonawanda; a
brother, John of Amherst; and
six grandchildren.

PaulA. Cline
MD'43
Paul A. Cline, MD '43, a retired Kaiser Permanente surgeon, died in Parma, OH, on
June 26, 2000, at age 80.
A resident of Strongsville,
OH, since 1972, Cline began
his ten-year tenure as chief of
surgery for Kaiser Perrnanente
Hospital in Parma a few months
after joining the staff in 1973.
He retired as a surgeon in 1989,
but continued working as a consultant at Kaiser's Musculoskeletal Clinic for a few years.
Born in Budapest, Hungary, Cline came to the United
States at a young age.
Following graduation from
US's school of medicine in
1943, he interned at Massachusetts Memorial Hospital in
Boston.
After a three-year stint in
the Army, he served residencies at former E. J. Meyer Memorial Hospital in Buffalo, NY,

2002

and at the Veterans Administration hospitals in Buffalo and
Batavia, NY.
For 20 years, Cline had a
general surgery practice in
Buffalo and was also clinical
assistant professor at UB and
an attending surgeon at
Kenmore Mercy Hospital.
He is survived by his wife of
28 years, Harriett "Hattie";
daughters, Sandra Schlerf of
Columbia, SC, and Barbara
Warren of Lawrenceville, GA;
son, Clifford of Dallas, TX; stepdaughter, Holly MacMurray
of Orchard Park, NY; stepson, Daniel Lewin of Los Altos,
CA; two grandchildren; three
great-grandchildren; and a
brother.

Earl K.
Cantwell,
MD'4S
Earl K. Cantwell, MD '45, a
former Erie County medical
examiner who practiced obstetrics and gynecology for many
years, died on April4, 2001, in
Kenmore Mercy Hospital, Town
of Tonawanda, NY, after a
lengthy illness. He was 80.
Born in Buffalo, NY,
Cantwell graduated from
Amherst Central High School
in 1938 and completed his
undergraduate and medical
studies at the then-University of Buffalo, where he received his medical degree in
1945. After interning at the
former E. J. Meyer Memorial
Hospital, he joined the Army
Air Forces, and in 1948 graduated from the School of
Aviation Medicine. He was
aviation medical examiner at
Griffis Air Force Base in
Rome, NY, before leaving the
service with the rank of
captain.

After returning to Buffalo,
he met Rita J. Roll, whom he
married in 1950. Cantwell
worked at Deaconess Hospital and maintained a general
practice until 1956, when he
decided to become an obstetrician-gynecologist and
moved his family to Indianapolis to serve a residency at
St. Vincent Hospital.
After working at the Sault
Ste. Marie Clinic in Michigan, Cantwell returned to
Buffalo in 1963. He was
county medical examiner for
15 years and Amherst town
physician for five, as well as
a school doctor for the Buffalo Public Schools. He also
was a civilian Armed Forces
examining officer for 21 years
and chief medical officer at
the Armed Forces entry station in Buffalo for 10 years.
Cantwell maintained an OBI
GYN practice in his Amherst,
NY, home before retiring in
1984.
"By temperament and
spirit, he was a physician, and
that calling defined his life,"
says his son, Kevin, of Amherst.
"His passion for medicine inspired two of his children to
become doctors as well."
In addition to his wife and
son, Kevin, he is survived by
two daughters, Dr. K.C.
Ackerman of Bethesda, MD,
and Mary Beth of Buffalo, NY;
two other sons, Earl K. II of
Buffalo, and Dr. Michael of
San Francisco, CA; and seven
grandchildren.

Ansel Robert
Martin, MD '48
Ansel Robert Martin, MD '48,
who studied dermatology
under Dr. Earl Osborne, died
on July 17, 2001.

&lt;Ii)

�Early nineteenth century

Italian tourniquet with a brass key and iron-cogged-wheel tightening

mechanism. The brass frame is stamped "Giannattasi In Napoli." The tourniquet has many brass and iron
decorative flourishes, including the fluting to the screw heads and the iron loop of the catch.
In the ear1y 18th century, Jean Louis Petit, a French surgeon, invented the screw tourniquet to control bleeding.
The device made thigh amputations possible and reduced risks associated with amputations below the knee.
Tourniquets similar to the one pictured here were still in use during the American Civil War.
The instrument is part of the Edgar R. McGuire Historical Medical Instrument Collection, housed in the
Robert L. Brown History of Medicine Collection, Health Sciences library, Abbott Hall, on the University at
Buffalo's South Campus.

�CM I SC

CATHY GEAqy

HE~LTH

p H A

]

SCIE CE LI~R RY
SOUTH C MPU
130 ASEOTT H ll
CAr-PUS "'1 IL

A

UB's HISTORY
OF MEDICINE
COLLECTION PRESENTS
PHARMACOPOEIA.

Digitally reproduced
prints from a pharma copoeia by Otto Karl
Berg (1815 - 1866) were
on display last fall in
University at Buffalo's
Health Sciences Library
(HSL),

outh Campus.

The botanical show
was developed by the
HSL and the university' s
iMedia staff and is the
first

in

a

series

of

"Art in the Library"'
exhibits intended to
promote the History of
Medicine

Collection

through the display and
sale of reproductions of
selected works.
F1·ed Kwiecien and
Don Trainor of iMedia
prepared

the

prints

from the original art in
the Berg volume, pub lished in Leipzig in

1863. Pictured is Colchicum
Autumnale (Autumn Crocus).

HP 0001

02

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P~ysician

ASSO CIATE VICE PRESIDENT FOR
UNIVERSI TY COMMUNICATIO NS
Dr. Carole Smith Petro

DIRECTOR OF PERIODI CALS
Sue Wuetcher

Dear Alumni and Friends,

EDITOR
Stepl1a11ie A. U11ger

ART DIRE CT OR &amp; DESIG N
Alan f. Kegler

AST SPRI

·c,

YOL READ ABOVI the pride and excitement we felt when Governor George

Pataki p roposed in his "State of the State" address that Buffalo be designated the site for a
world-class Center of Excellence in Bioinformatics-a collaborative effort involving the
state, industry partners and area academic institutions.
In january 2002, this proposa l moved one step closer to rea lity, when Governor Pataki
visited Buffalo to announce $200 mi ll ion in state and private-sector funding for the center
(see article on page 14 for details on this announcement).
The Center of Excellence in Bioinformatics-combined with the establishment of the
Strategically Targeted Academic Research (STAR) Center for Disease Modeling and Therapy Discovery in Buffalo-will have a sign ificant influence on the types of basic research
we will be conducting at our school in the decades ahead. It will also affect
the growth and development of our school's faculty because we will be
hiring individuals to fi ll positions that will mesh with the center's goals.
Working synerg istically, these two ce n ters-with the aid of
supercomputers-will place our school in an excellent position to take a
lead role in research that will help provide a better understanding of interactions between molecules and proteins, and disease states and genetics.
Ultimately, such studies hold great promise for the timely development of
novel drugs, as well as the discovery of new, more viable ways to manage and treat disease.

DE SIGNER
David f. Riley

DESI GN A SS ISTANT
Kare11 Lichner

Co NTRIB UT ING WRITERS
Lois Baker and Elle11 Goldbaum

PR ODUCT I ON COO RDI NATO R
Cynthia Todd-Flick

UNIVERSITY AT BUFFALO
S CHOO L OF MEDI CINE AND
BIOM EDI CA L S CIE NC ES
Dr. Michael Bemardino, D ea 11
E DIT ORIAL BOARD
Dr. john Bodkin
Dr. Marti11 Brecher
Dr. Harold Brody
Dr. Linda f. Corder
jason Hoffman II, Class of 2004
Dr. james Ka11ski
Dr. Eliz abet/1 Olmsted
Dr. james R. Olson
Dr. Steph e n Spaulding
Dr. Bradley T. Truax
Dr. Frat1k/in Zeplowitz

The establishment of the Buffalo Center of Excellence in Bioinformatics is extremely
important to our school, and we will continue to update you on the progress of this exciting
venture in the months and years ahead.
I am also p leased to announce that Suzanne Laychock, PhD, professor and associate
chair of the Department of Pharmacology and Toxicology at UB, has agreed to serve as the

T EAC HI NG H OSPITALS
Erie County Medical Center
Roswell Park Cancer In stitute
Veterans Affairs West ern
N ew York Healthcnre Syst em
K ALE I DA H EAl T JI :

significant role in determining what research will be conducted at our school in the future .

Th e Buffalo General Hospital
Til e Cl1ildren 's Hospital of Buffalo
Millard Fillmore Gates Hospital
Millard Fillmore Suburban Hospital

She will also help deter mine how resources will be allocated for th is research and will

C A TH O II C

new senior associate dean for research at our school, replacing Bruce Holm, PhD, who has
been named a senior vice provost at UB. In her new position Dr. Laychock wi ll have a

oversee the recruitment and hiring of new research facu lty.
Recent data provided by the Association of American Medical Colleges (AAMC)
indicates that our school's performance in basic and clinical research is very good and, as a
result, UB has moved up in AAMC rankings in this area. Certainly this improvementalong with the recent steps made toward establishing a center in bioinformatics-gives us

H EAcr u S rsrE M:

Mercy Health System
Siste rs of Clwrity Hospital
Niagara Falls Memorial
Medical Center
@

UNIYEISITY lT IUFFlLO.
THE STATE UNIYEISITY II NEW Ylll

a positive context within which to work as we strive to conduct research that will help
reshape the fie ld of medicine as it enters the new era of proteomics and genomics.
Finally, I would like to announce that in the coming year we are planning to recruit new
faculty in surgery, pediatrics, neurology and medicine. Currently, we are conducting
national searches for chairs of surgery, neurology and rehabilitation medicine, and !look
forward to updating you on these once completed.

MI C HAEL E. BERNARDINO . MD , MBA
Dean, Sclwol of Medicine a n d Biomedica l Sciences
Vice President for Hea lt h Affairs

Letters to the Editor
Buffalo Physician is published quarterly
by the University at Buffalo School of
Med icine and Biomedical Sciences in
cooperation with the Office of
Communications.
Letters to the Editor are welcome
and can be sent c/o Buffalo Physician,
330 Crofts Hall, University at Buffalo,
Buffalo, NY 14260; o r via e-mail to
bp-notes@buffalo.edu.
The staff reserves the right to edit all
submissions for length and clarity.

T~

~

University at Buffalo

T11e State University ofNew York

�V 0 L U M E

N U M B E R

36,

0

Features

2

Minimal Access Surgery for Kids
Buffalo's pediatric surgeons
are leaders in performing and
teaching laparoscopic surgery
BY

16

24

S.

A. UNGER

APlace for Business in Medicine
A student's perspective on UB's
new MD/MBA Program
BY

Jennifer Wiler, Class of 2003

Imaging and Imagination
A look back at a decade of
research: Pet Center marks
its tenth anniversary

The Buffalo Center of Excellence in Bioinformatics receives $200 million in state, federal
and private-sector support. Article begins on page 14.

BY ALAN LOCKWOOD, MD
COVER PHOTOGRAPH, CLOCKWISE, FRONT RIGHT, PEDIATRIC SURGEONS
PHILIP GLICK, MARC LEVITT , M I CHAEL CATY , AND GuY BRISSEAU

15

ational
Science
Foundation
grant bolsters
computer
storage capacity

21

Sung and White
scho larship
recipients
Alpha Omega
Alpha scholars
inducted

22 Orvan

Hess,
Class of 1931,
a pioneer in
fetal-heart
monitoring

30 Suzanne
Laychock, PhD,
named senior
assoc iate dean
for research

31 Maxine Hayes,

36 Message from

MD '73,
honored by
theAMA

37 james Platt

33 ew faculty at

Society

Roswell Park

42 News from
your UB
classmates and
other alumni

the directorthe cost of
medical
education then
and now
White Society

40 Edmund Hayes
~-

\ I\

JUN ' 5

���NE OF THE THINGS THAT IS DIFFERENT ABOUT OUR PROGRAM

in Buffalo compared to others

around the country is that our entire faculty has embraced the goal of converting over to
minimally invasive surgery as a way to think about every operation;' says Glick, who also serves
as interim chair of surgery at the University at Buffalo and professor of surgery and pediatrics.
"Five years ago, each faculty member made a commitment to this and said, 'I'm on board.'
We decided we were going to learn together, sharing both our successes and our mistakes,"
he adds. ''Although the learning curve was just as steep, I believe we got to the flat part of the
curve much quicker than we would have otherwise."
At the time they began the transition, the surgeons at
CHOB were applying minimally invasive surgical techniques to about 5 percent of their cases; currently, they
are up to about 50 percent, and their goal is to eventually
reach 100 percent. Convinced that these proven techniques provide a host of benefits to patients and their
families, as well as savings in healthcare costs, they now
want to do for other pediatric surgery training programs
in the country what they've done for their own.
"There are some programs out there that are still at
5 percent, so the children in those cities are not benefiting
from these great techniques," says Glick. "We'd like to
help change that."

An Operating Room with a View
The new MASC includes two state-of-the-art operating
rooms custom-designed for the performance of multidisciplinary, minimally invasive surgery, including
laparoscopy, thoracoscopy, endoscopy, arthroscopy and
cystoscopy. All equipment in each room is suspended
from ceiling booms and is totally automated by a voiceactivated computer controlled by a headset worn by the
surgeon. Simply by talking into this headset, he or she
can direct all the equipment located on the booms, in cluding flat-screen televisions used to view procedures in
real time as transmitted from cameras embedded in the
tips of the endoscopes.
[n addition, cameras built into the lights above the
operating table capture on-screen a bird's-eye view of
what the surgeon is seeing with his or her own eyes.
Situated unobtrusively in the corner of each room is
a "communication control center" that allows images
captured by these cameras to be telecast to any location
in the world equipped for teleconferencing, which
provides the MASC with expansive telesurgery and
"telemen to ring" capabilities.

I u f fa I o Physician

Spri11g

2002

On October 10, 2001, the first live operation from the
MASC was broadcast to a meeting of the American
College of Surgeons in New Orleans. On March 15, 2002,
a second surgery was broadcast from the MASC to a
meeting of the Society of American Gastrointestinal
Endoscopic Surgeons in New York City.
Also located within the MASC are state-of-the-art
conference room facilities and an observation room,
where medical students or other visitors can view surgical
procedures being performed and telecast on a highresolution screen mounted in the room.
Surrounding this minimalistic surgical environment
are walls and ceilings painted with soft blue clouds and
floating teddy bears. Children can select a cartoon movie
from a collection of 20 videos donated by Warner Brothers and watch it on the four television screens in the
operating room while anesthesia is administered. Or they
can choose to play Xbox games donated by Microsoft.
"So the kids go off to sleep watching the cartoon or
playing the games," says Glick.

A New Way to Teach and
Train Students

I

eveloped in tandem with the MASC is the Miniature
Access Teaching, Training and Research (MASTTAR)
Center, housed in the Biomedical Research Building
on the campus of the University at Buffalo School of
Medicine and Biomedical Sciences, located five miles from
CHOB. This $900,000 center-linked fiberoptically to the
MASC- is a component of the Buffalo Center of Excellence in Bioinformatics (see related article on page 14)
and is supported by the university for the purpose of
teaching medical students, residents, fellows, nurses and
technicians about minimally invasive surgery.
The idea to make the MASTTAR Center a component of

�l

the Center ofExceUence in Bioinformatics was championed
by Bruce Holm, PhD, former senior associate vice president
for health affairs at UB, who was recently named a senior
vice provost at the university.
"Bruce Holm's efforts have been an essential component of the MASTTAR," explains Marc Levitt, MD, UB
assistant professor of surgery and pediatrics and
medical director for both the MASC and the MASTTAR
Center. "Several years ago, he foresaw how it could be
a part of the bioinformatics center, and because of his
involvement from the start, the university has been
extremely supportive of the MASTTAR Center by providing a significant amount of funding, as well as by
encouraging multidisciplinary collaborations with engineers, computer scientists and others on campus."
he MASTTAR Center includes an eight-station laboratory
that is used to conduct basic-science projects and minimally invasive surgery training courses. Located adjacent
to a fully-equipped surgery suite that is used in conjunction with this training, the MASTTAR Center also houses
cutting-edge computer facilities, fiberoptic connections
and office space available for personal computing needs,

including data storage and reduction, statistical analysis
and graphic presentation.
Also located in the center is an $850,000 Zeus surgical
robot donated by Computer Motion. This highly sophisticated robot is an earlier model of one that is located in Buffalo General Hospital's (BGH)* Center for Less Invasive
Cardiac Surgery and Robotic Heart Surgery, which is directed by Hratch Karamanoukian, MD, a UB assistant clinical professor of surgery (see page 9 for details on a robotic
heart surgery trial currently under way at this center).
"Dr. Karamanoukian is one of the premier cardiac
surgeons in the country, and he routinely performs coronary anastomoses with the Zeus robot," says Levitt, who
adds that Karamanoukian collaborates on a number of
projects at the MASTTAR Center. "Basically, Dr. Glick
worked out a deal with Computer Motion, where they
gave Dr. Karamanoukian a newer model of the robot, and
the MASTTAR received the older one he had been using."
In the future, surgeons fully expect that robots will
merge with minimally invasive surgery to provide surgical
applications that could only have been imagined a few
years ago. For example, NASA and the military are interested in this technology, which, theoretically, could allow
an operation to be performed on an
astronaut in space by a surgeon on Earth,
or on a soldier on a battlefield by a surgeon located miles away at a secure site,
according to Levitt. These scenarios recently took one step closer to becoming a
reality when Michel Gagner, MD, a
surgeon at Mount Sinai Hospital under
whom Levitt trained, performed a

Spri11g

2002

Bu If a I o Ph ysi cian

5

�(bottom right)
(bottom left)

The stmulator was
donated to the
MASTTAR by

Computer Motion.

�laparoscopic gallbladder operation on a woman in France
from his office in New York City.
" In addition to these applications, the reason we're
interested in robots is because they can do repetitive
motions in very small places, very accurately, and eliminate any tremor a surgeon might have, so you can be
incredibly precise," explains Levitt.
In pediatric surgery, this instrumentation would be
particularly advantageous for such procedures as esophageal repairs on newborns, according to Glick. It would
also be a valuable tool for ligating extra blood vessels
between the heart and lungs in a procedure called patent
ductus arteriosus ligation, and may have some applications to biliary atresia, where surgeons sew extremely
small pieces of the intestine to the liver and bile ducts.

A

t the MASTTAR Center, Glick and his colleagues also
are working to develop and test a wide variety of new
equipment and technologies related to minimally invasive surgery. Currently, for example, they are collaborating with a multidisciplinary Surgical Simulator Team to
develop a next-generation laparoscopic virtual-reality
surgery simulator in partnership with two companies:
Mentice Corporation, of San Diego; and Silicon Graphics, of Mountain View, California.
Members of this team include Christina Bloebaum,
PhD, UB Professor for Competitive Product and Process
Design and director of the ew York State Center for
Engineering Design and Industrial Innovation
(NYSCEDII) on UB's orth Campus; and Eliot Winer,
PhD, UB research assistant professor of engineering and
applied sciences and the associate director ofNYSCEDII;
Thenkurussi Kesavadas, PhD, UB assistant professor of
mechanical and aerospace engineering and director of
the UB Virtual Reality Laboratory; Russ Miller, PhD, UB
professor of computer science and engineering and director of the university's Center for Computational Research
(CCR); and Thomas Furlani, PhD, associate director of
CCR and UB research associate professor of chemistry.
Each of the three entities that makes up the Surgical
Simulator Team provides specialized expertise that makes
this project possible, according to Glick and Levitt. CCR

primarily provides the computing power and knowledge;
YSCEDII provides advanced virtual-reality technology;
and the VR Laboratory is contributing groundbreaking
work on hap tics. "Haptics involves, for example, a surgeon
using virtual-reality technology to pick up an instrument
on the computer screen and being able to feel its weight
and consistency with his hand," explains Levitt.
The surgical simulator under development at the
MASTTAR Center will have two specific applications.
The first is preoperative planning, where radiographic
images, such as CAT scans or MRis, are burned onto a
CD and loaded in a computer, where the images are
reconstructed in three dimensions.
"If you have a patient with a tumor in his liver, which
has a lot of blood vessels around it, you could reconstruct the liver in three dimensions and then remove
certain components of the anatomy to see how close the
tumor is to the main blood vessels," says Michael Caty,
MD, a CHOB pediatric surgeon and UB associate professor of surgery. "This is work we have already done, and
it can help the surgeon avoid potential problems and
discover safer approaches to take."
The second application being developed is one that
will enable an individual to simulate an operation on the
computer for training purposes. "If you had a surgical
resident learning to remove a gallbladder," says Levitt,
"she could perform the whole operation before she met
her first patient. It's just like the flight simulators used by
the airlines, and in both cases it really enhances safety."
In addition to these and other research and development projects, Glick has established a clinical laboratory
at the MASTTAR Center that focuses exclusively on
minimally invasive surgery. He explains that surgeons
working with adults have recently begun to examine how
minimally invasive surgery affects the physiology of
their patients; however, few such studies have been
conducted in the pediatric population .
"Our goal, therefore, is to explore how this type of surgery impacts on the physiology of children," says Glick.
"For example, when you insufflate the abdomen of a fivepound infant with carbon dioxide [in order to create a
hollow space so you can perform a minimally invasive

Spring

2002

Buffalo Physician

7

�surgical procedure], what exactly is going on in that little
baby? This is the type of question we are asking in our
research."

Stitching in the Curriculum Piece
Glick is tremendously enthused about ways in which these
research projects and the technologies made available
through the MASTTAR Center will affect the training of
medical students and surgical residents at UB. He also
feels the center can play a role in reversing trends in
medical education over the past decade that have resulted
in fewer students choosing surgery as a career.
"Over the past 10 or more years, because there has been
such an emphasis on primary care, students have lost valuable contact time with surgeons and other specialists and,
as a result, some of the best students have been turned on
to things other than surgery," explains Glick.

0

etermined to do his part to counter this trend, Glick has
embarked on an effort to build what he calls "a farm team
for the Department of Surgery." To accomplish this, he
has begun a surgical interest group (the "SIG") at UB for
first- and second-year students, and he is working with
administrators to introduce changes in the curriculum that, among other
things, will expose students to stimulating new
laboratory experiences.
Guy Brisseau, MD, CHOB
pediatric surgeon and UB
assistant professor of surgery and pediatrics, is collaborating with Glick on the details of this new secondyear elective.
There are inducements for third-year students, as well.
On the first day of their surgery rotation, the students are
brought to the MASTTAR Center, where they begin learning basic hands-on skills, such as suturing, the placement of
chest tubes and endotracheal intubation. Also, students can
test their hand-eye coordination by attempting to take balls
from one beaker and place them in another using the
laparoscopic virtual reality-surgery simulator/trainer (the
same simulator for which the MASTT AR Center researchers are working to develop a next-generation model).
"The student's proficiency on this trainer is really
amazing," notes Levitt. "If you took a senior surgeon and
put him next to a third- or fourth-year medical student on
the virtual-reality simulator, the student would do better
because they have grown up playing video games and so

8

Bu ff a l o Physicia n

Spring

2002

are used to looking at a TV screen while working with their
hands. People 50 years and older never did this as children.
The computer can record how quickly the students learn
these skills, and they are very adept right away."
Glick is also developing an entirely new curriculum and
training for pediatric surgical residents, a goal he says the
MASTTAR Center is "totally suited to support." Recently,
he created a teaching program in miniature access surgery
for third-year residents aimed at helping them to acquire a
clearly defined set of surgical skills prior to being allowed to
work in an operating room. "In England, they're very into
this kind of'programmed learning,"' notes Glick. "Basically,
you have to be credentialed in certain skills before you can
operate on humans. In this country, a lot of teaching has
been done in the OR, but we're going back to the basics now
and our residents are going to have to be credentialed in certain skills before they can progress to the operating room."
Alan Posner, MD, UB assistant professor of clinical
surgery and chief of laparoendoscopic surgery at Erie
County Medical Center (ECMC) and Buffalo General
Hospital, will collaborate with Glick and others to help
train the residents in acquiring these skills. In addition,
ECMC has been fiberoptically linked to the MASTTAR

Center, and in February 2002 Posner taught a course on
nephrectomy for urologists. For the course, a nephrectomy was performed at ECMC and broadcast live to a
conference room on UB's campus.
In addition to medical students and residents, practicing surgeons-many of whom attended medical school
before minimally invasive surgery was taught-now are
being retrained in these techniques utilizing teleconferencing and "telementoring" capabilities at the MASC. In
reference to this latter mode of training, Glick explains
that there are a number of new operations he and his
colleagues have developed and want to teach to others, but
they don't have time to travel to locations to be present
with surgeons who are performing the operation for the
first time on their own. Instead, the surgeons can come to
Buffalo to train and when they return home to a facility
whose operating rooms are equipped with teleconferenc-

�ing capabilities, they can then perform the new procedure while being closely monitored by a CHOB
surgeon situated in the MASC conference room.
A key to taking the center's teleconferencing capabilities to such an advanced stage is an ongoing collaboration
between MASC faculty and Lisa Stephens, associate director for Distance Learning Operations at UB. Due in
large part to the technical assistance provided by Stephens
and her group, the MASC this year is offering six postgraduate teleconferencing courses, not only to physicians,
but to nurses and technicians, as well. The first course,
held on January 26, 2002, was attended by 80 operating
room nurses and technicians representing 30 hospitals in
five different cities in Western New York.

f

or the past five years, a course has been taught at Miami
Children 's Hospital to train pediatric surgery fellows in
pediatric laparoscopy. This year, the course moved to
Buffalo, where it was taught by the CHOB pediatric team
of Glick, Levitt, Caty and Brisseau. Joining this team as

v1s1tmg professors were four other leading pediatric
surgeons from around the country, including Raleigh
Thompson, MD, Steve Rothenberg, MD, Keith
Georgeson , MD, and Thorn Lobe, MD. Held in
April 2002, the course was attended by more than 20
pediatric surgery fellows from across orth America.
In addition, a pediatric laparoscopic fellow, funded
by Ethicon Corporation, currently is being trained at
CHOB in minimally invasive surgery. The fellow,
)oselito Tantoco, MD, is from the Philippines; after two
years he will return to his homeland, where he will be
the only pediatric surgeon trained in these skills.
Another exciting development is the completion of a
fiberoptic connection between the MASC and Butler
Auditorium in UB's School of Medicine and Biomedical
Sciences, which equips that venue with telesurgery capabilities. The new telecommunications system was unveiled on March 19, 2002, for a class on minimally invasive
surgery sponsored by UB's Mini Medical School , which
seeks to educate the community about science and medicine. More than 300 people attended the class,
which was taught by Glick while Levitt simultaneously performed an operation at CHOB,
key portions of which were telecast live in
Butler Auditorium throughout the lecture.
"Our multifaceted approach is the thing
that sold our program to our corporate sponsors," Glick says, explaining that the MASC
and the MASTTAR Center are supported by
grants from the Stryker Corporation; Ethicon
Endo-Surgery, a subsidiary of johnson and
Johnson; Berchtold Corporation; and Steris
Corporation. The MASC has also been supported by the Children's Hospital of Buffalo
Foundation, and the MASTT AR, by funds
from UB.
"There are many people knocking on the
doors of corporations, saying they want to
be a center of excellence," adds Glick. "But
what made us unique is that we were the first
pediatric group to approach these sponsors
and offer them the clinical excellence, as
well as teaching, training and research, in
one program. " CD

*Children 's Hospital of Buffalo and Buffalo
General Hospital are part of the Kale ida
Health System.

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luflalo Physician

9

��inimally invasive surgery is the antithesis of the traditional "open access" approach to surgery in which an
operation is performed through an incision in the body large enough to accommodate a surgeon's hands
wielding a scalpel, suction tubes or other instruments. Alarge, open wound brings with it collateral tissue
damage, risk of infection, pain and alengthy recovery, not to mention permanent, often prominent, scarring.
The ability to perform surgery through small "ports,"
or keyhole incisions, became possible with the invention
of the endoscope, a rigid or flexible tube a few centimeters
in diameter equipped with a light and camera at one end.
By introducing the endoscope and other tiny instruments
into small, strategically located incisions via conduits
called "trocars," surgeons can complete almost any task.
Gynecologists have been performing laparoscopic
procedures for several decades; in many ways, they pioneered the field of minimally invasive surgery as we
know it today. The first laparoscopic cholecystectomy
(gallbladder excision) was performed in 1987, and since
then laparoscopy has been applied to many surgical
problems, leading some to predict that minimally invasive surgery will make up greater than two-thirds of
operating room cases in the near future. Despite its

success in adults, however, this form of surgery was rarely
used in infants and children until recently.
"There was a lot of resistance to minimally invasive
surgery in pediatrics, and some was for bad reasons that
have taken us a decade to get past," says Philip Glick, MD,
surgeon-in-chief at Children's Hospital of Buffalo
(CHOB)*, executive director of its new Miniature Access
Surgery Center (MASC) and UB professor of surgery
and pediatrics and interim chair of the Department of
Surgery (see previous article).
These reasons include the fact that postoperative pain
in children was not well understood and was underestimated, so the need for a more minimal approach was not
deemed necessary.
Also, because pediatric surgeons prided themselves on
making small incisions to begin with, the advantages of

Spring

2002

I u If a I o Phy s i ci an

11

�even smaller incisions were not at first recognized, but
instead dismissed by early critics of laparoscopy in
pediatrics as merely "cosmetic."
Other major stumbling blocks were the steep learning
curve for minimally invasive surgical techniques and the
fact that the equipment was costly and time consuming
to set up.
Finally, the unavailability of instruments that were
small enough in size for infants and children served to
effectively stymie those few pediatric surgeons amenable
to exploring these innovative surgical procedures.
Over the past five years, Glick and his colleagues at
CHOB have played a leading role in surmounting many
of these barriers, as well as in pioneering new minimally
invasive surgery techniques for use in children that,
ironically, now are being adapted by surgeons working
with adults.

A Quest to Move the Field Forward

8

ecause there are 35,000 general surgeons in the United
States and only 400 pediatric surgeons, the manufacturers of medical instrumentation were not interested
in downsizing their tools for use in pediatrics, claiming
that the market was not big enough.
"It took a few companies to believe in what we were
doing to realize that we were going to push the envelope
on this technology, and then they started miniaturizing
the equipment for us about five years ago," says Glick.
So, instead of 10- to 12-millimeter telescopes-about
the size of a chunky pen-pediatric surgeons now can use
three- to five-millimeter tools that also have been shortened in length. The new instruments have proven
so effective that general surgeons have started using
them, especially in adults for whom scarring is a concern.
With the new instruments on board, other barriers
began tumbling, and minimally invasive surgery in
children has taken off at a brisk pace, especially given
the obvious benefits to patients and the bottom line
for hospitals.
"The benefits of minimally invasive surgery for
children are significant," says Marc Levitt, MD, UB
assistant professor of surgery and pediatrics and
medical director for the MASC and the Miniature
Access Teaching, Training and Research (MASTTAR)
Center at UB.
" It leaves little or no scarring, and the risk of pul monary problems is greatly reduced. Also, the chil dren have shorter hospital stays, and once they are
discharged they can return to school and normal
activities. Essentially, after most of these operations

12

I u If

I

II P h J s i e i a n

S p ri 11 g

2 00 2

there are no restrictions on their activities."
Levitt says that evidence is now pointing to a correlation between a decrease in pain due to the smaller incisions and the decrease in pulmonary complications.
"Because they have less postoperative pain, they are
better able to cough and breathe deeply," he notes.
In addition to improved patient care, the equipment
and instruments that have been developed are resulting
in reductions in healthcare costs. The state-of-the-art
operating rooms in the MASC can be readied for surgery
with the flip of a switch, in comparison to the lengthy
and labor-intensive set-up procedures required for
minimally invasive surgery in years past. "We basically
have a 'preflight' checklist, where the nurses walk into
the OR and in five minutes it's ready to go; all they have
to do is set up the sterile equipment," says Levitt.
In addition, recent studies have shown that the
dollars saved in turnaround time for these operating
rooms-where six to eight cases can be done in a day
instead of just four- will pay for them in a short time.

Leaving No Procedure Unturned
By having all the latest equipment and instrumentation
at their fingertips, the pediatric surgeons at CHOB have
become innovators in their field, challenging themselves
and their peers to take a fresh look at all procedures,
leaving none overlooked. What they are finding is that
many surgeries not only can benefit from the adaptation
of minimally invasive techniques, but in some cases can
be converted over to these new techniques exclusively.
An example of such a surgical procedure involves
the treatment of Hirschsprung's disease, a congenital
disorder in which the bowel malfunctions, resulting in
severe constipation.
This condition once required three separate operations during a baby's first six months of life, with each
surgery involving a five- to seven-day hospital stay.
Using a laparoscopic approach, surgeons at CHOB now
perform one three-hour operation that requires no
incision. The procedure is done during the first month
of life, and the baby can go home in one or two days.
"We've done 20 of these operations using telescopes.
This gives us a lot better visualization and mobilization
from above, which makes the operation safer," says
Michael Caty, MD, who, along with Levitt, performed
this procedure at the MASC while it was being broadcast
live to a group of several hundred surgeons watching it
on a screen at the annual meeting of the American
College of Surgeons in ew Orleans in October 2001.
Caty and Guy Brisseau, MD, along with Glick and Levitt,

�make up the pediatric surgery team at CHOB and are
the only pediatric surgeons in Western New York.
Building on this work, these surgeons have begun
using trocar-less surgery in exceptionally small babies in
need of minor operations.
"Instead of using a trocar, we introduce the surgical
instruments directly into the abdominal wall through
a three-millimeter
incision," says Glick.
"This greatly reduces
scarring, and it allows
you the flexibility of
putting the instru-

to eight hours to complete. ow, with the assistance of
the pediatric surgeons at CHOB, the orthopedists are
using thoracoscopic techniques to complete this phase
of the surgery, reducing it to a two- to three-hour
process and avoiding a large incision.
The pediatric surgeons' role is to insert all the trocars
and camera instruments for the orthopedic surgeon.
Once this is done, they can either go down the hall to
the MASC conference room, where they can observe the
procedure via telesurgery, or they can go next door to
perform their own surgery while still being available to
communicate with the orthopedic surgeons should the
need arise.

ments tn anywhere
you want. In the past,
we were very rigid
about where we placed our trocars, but
now we understand
that this can be cus-

As they eagerly look to the future to explore how
other minimally invasive techniques can be incorporated into surgical procedures, the pediatric surgeons at
CHOB take pride in the fact that they consider no operation outside the bounds of their scopes. "When we started doing minimally invasive surgery
here five years ago, it involved about 60 of the 2,000
cases we complete each year. ow we're up to about
1,000 cases," says Glick.
"And the ones we're not doing, we're still asking
ourselves, ' Can we do it?' Right now, the answer is,
'We can't,' but we keep asking ourselves that question
every day, and as the equipment gets better and we gain
more experience, we'll be approaching 100 percent.
It's just a matter of time." CD

tomized for each operation."
The CHOB surgeons also are collaborating with
specialists in other fields to develop innovative alterations to surgical procedures that significantly affect
quality of life and outcomes for patients.

A

dramatic example of this is the work they've been
doing with orthopedic surgeons to correct spinal
deformities resulting from congenital scoliosis. In this
procedure, the orthopedic surgeons at CHOB-Robert
Galpin, MD, and Douglas Armstrong, MD-must first
release the ligaments on the child's anterior spine, after
which the patient is turned over and the corrective
hardware inserted. In the past, using the traditional
open-surgery approach, the surgeon had to make a large
incision across the chest or the abdomen to access the
spine and release the ligaments, a process that took six

*Children's Hospital of Buffalo is part of the Kaleida
Health System.
Lois Baker, senior editor in News Services at the University at Buffalo,
contributed to this story.

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13

�RESEARCH

E

W

S

Bioinformatics Center
Receives 8200 Million

Bv
ELLEN
GOLDBAUM

-Merging of high·end technologies to foster advances inhealthcare and science

n December 6, 2001, ew York
State Governor George E. Pataki
announced $50 million in state
funding and more than $150 million
in private-sector funding for the
Buffalo Center of Excellence in Bioinformatics, a collaborative effort
involving ew York State, industry
partners and academic institutions.
Building on the emerging discipline of bioinformatics, which uses the
power of supercomputers to interpret data
in the biological sciences at the molecular
level, the new center will merge high-end
technology, such as supercomputing and
visualization, with expertise in genomics,
proteomics and bioimaging to foster
advances in healthcare and science.
First proposed in January 200 l by
Pataki, the Buffalo Center of Excellence in
Bioinformatics is an integral part of the
governor's plan to develop centers of
excellence across the state to harness the
strengths of universities and the private
sector to create strategically targeted hightechnology centers of innovation, all
aimed at spurring economic development
and creating jobs.
Since that initial announcement, the
Buffalo Center of Excellence in Bioinformatics has attracted funding from major
national corporations. In December, Pataki
acknowledged that efforts to garner such
funding were bearing fruit and that the
center "will go forward. "
In addition to an "initial installment"
of $50 million from New York State, he
announced the following commitments in
software, hardware, venture capital, cash
and equipment from the industry partners

14

I u I I a II Physic i a a

S prir~ g

2 00 2

to date: Veridian will contribute $62.5 million; Compaq, $42.6 million; Informax,
$20.8 million; and a group ofWestern New
York businesses is investing 15 million.
Stryker Communications is providing
$7.2 million to create a communications
network for the center (see related article
on page 2), and Dell Computer Corporation and Sun Microsystems Inc. together
are providing more than $1 million.
Other partners include Invitrogen
Corporation, Q-Chem, SGI, Amersham
Pharmacia Biotech, AT&amp;T, Wyeth Led erie,
Human Genome Sciences, Inc. and the
Alfred P. Sloan Foundation.
The level of the commitment of New
York State and the industry and academic
partners, Pataki said, will assure that the
center will be "the state-of-the-art facility,
not just in the United States, but in the
world"; and he also predicted that the
center "will transform Western ew York
into a 21st-century economy."
On behalf of the University at Buffalo,
which is taking the lead among the center's academic partners, UB president
William R. Greiner thanked Pataki for his
vision, leadership and continuing commitment to Buffalo- iagara. "It is much
appreciated in this region," Greiner said,
"and we will work to make you proud."
In addition to support from the state,
the Buffalo Center of Excellence in Bioinformatics will receive funding from the
federal government. On December 7,
Representative Thomas Reynolds an nounced that $3 million had been earmarked for the center in the House version of the defense appropriations bill.
Senator Hillary Rodham Clinton worked

hard to supplement this allocation in the
Senate, and on December 21 she and Representative Reynolds announced $3.1 million in funds from two separate Congressional appropriations, providing important start-up costs for the initiative.
The Buffalo Center of Excellence in
Bioinformatics will be headquartered in a
150,000-square-foot facility to be built on
the Buffalo-Niagara Medical Campus (formerly known as the "High Street medical
corridor") and will house drug-design and
research laboratories, high-performance
computational facilities, 3-D visualization
capabilities, product commercialization
space and workforce training facilities.
The center is a natural progression of
the pioneering work that the center's major
research partners-the University at Buffalo, Roswell Park Cancer Institute and the
Hauptman-Woodward Medical Research
Institute- have been doing for years in the
areas of high-performance computing and
visualization, structural biology, genomics,
proteomics, pharmaceutical science and

�generation of custom gene "chips" through
the generation of DNA microarrays.

Global link for Bioinformatics Center
In a related development, the University
at Buffalo has entered into a new hightechnology partnership with Biopharma
Ireland, Ireland's new national institute
focused on biopharmaceutical research
and development, giving the Buffalo
Center of Excellence in Bioinformatics an
important international connection.
UB and Columbia University were
named as Biopharma Ireland's first U.S.
partners in an announcement made on
March 27, 2002, by U.S. Senator Hillary
Rodham Clinton.
Biopharma Ireland was established by
Dublin City University and Athlone Institute of Technology to promote research
leading to the discovery of new pharmaceuticals and to the creation of new companies and investments based on that
research in Ireland and ew York State.
"As a true Center of Excellence we need
not only national, but international, connections and recognition," says UB Provost
Elizabeth D. Capaldi, PhD. "Ireland has
strong computer and pharmaceutical industries and is an ideal partner for our
bioinformatics effort. We are pleased to
be able to have Biopharma Ireland as a
partner."
Bruce Holm, PhD, UB senior vice provost and the university's representative at
the announcement, notes, "It only makes
sense that as a center of excellence,
Buffalo's bioinformatics center should
be linked with other centers of excellence.
"In particular, Ireland has made substantially more of an investment in pharmaceutical research than most other
places in the European community," he
says. "With our partners in Ireland, as
well as with Columbia, this is a natural,
complementary partnership for UB."
The pharmaceutical companies Elan,
Wyeth (a subsidiary of American Home
Products) and Schering-Plough recently
have made major investments in Ireland.

Biopharma Ireland also is putting resources into developing spin-off biotech
companies that will benefit both Ireland
and New York State.
UB's partnership with Biopharma
Ireland has its roots in previous research
collaborations with Irish institutions facilitated initially by the Atlantic Corridor
USA, a Buffalo-based, non-profit alliance
created to link the NAFTA and European
Union markets.
Last semester, UB's Institute for Lasers,
Photonics and Biophotonics and the
Hauptman-Woodward Medical Research
Institute hosted visiting researchers from

the University of Galway and the Athlone
Institute of Technology.
UB has been partnering with Columbia
University on the Northeast Structural
Genomics Consortium, a $25 million
project involving nine institutions to study
structural genomics, a new field dedicated
to determining gene function by defining
the protein structure encoded in a gene's
D A sequence. UB's Center for Computational Research, one of the world's
leading academic high-performance
computing sites, serves as the computational backbone for the ational Institutes of Health-funded project. ( D

Sp r i 11 g

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Buffalo Physician

15

�16

lallala Hysiciaa

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�Sprtng 2002

1111111 .. JSICIII

17

�hile the general public may not fully understand how business skills can help today's physicians function more effectively in our complex
health care economy, medical students do-and increasingly they are seeking ways to obtain these skills.
In response to this growing demand. UB'sSchool of Medicine and Biomedical Sciences teamed up with the School of Management in
1997 to design an innovative program aimed at providing business skills to medical students. This collaboration has since resulted in the
formal establishment of an MD/MBA program at UB, which last spring matriculated its first graduate.
The new program, one of

MBA student Michael Chilungu, Class of

neurship, which may help them to open

17 MD/MBA programs in the

2003. " I see a need for physicians who are

their own practices, participate in hospital

country, was designed to allow medical students to obtain a dual degree in medicine

conversant in the business aspects of medi cine to serve as an antidote to this problem.

administration, serve as managers in health
maintenance organizations, or simply

and management in five years, instead of the

l t is they who can best reconcile the need for

improve their understanding of personal

six it would take if the degrees were earned

sound financial management with quality

finance.

independently. Students enrolled in the pro-

patient care."

gram spend years one and two completing

gram is that students are required to complete

traditional preclinical medical school

also Class of2003, had no previous business

a semester of internship training, which helps

coursework. They then spend the following

experience before entering the MD/MBA

ground coursework in the realities of the

year as full-time MBA students, after which

program. Instead, she credits her clinical

market economy. To date, UB students have

they return to medical school to complete

experience in medical school and intern-

completed internships that have involved

their third-year medical clerkships and the

ships at Independent Health as her primary

performing quality assessment research in

required fourth-year medical rotations.
They conclude the five-year dual-degree

motivation to better understand the business of medicine.

Erie County Medical Center's Emergency
Department; developing and facilitating a

"I became interested in the program after

course in medical ethics; working as an ac-

The reasons students cite for entering the

I began working with physicians during my

countant; and assisting in product develop-

program are as eclectic as the choice of a

outpatient experiences as a first-year stu-

ment and strategic planning at Cognigen

medical specialty. Some report having felt
intimidated by financial jargon, others say
they have been unsure of what will be

dent," says Perez. "I realized that most phy-

Corporation, a local firm that performs sta-

sicians were overworked, pressured for time
and very frustrated with the effect managed
care is having on them and their practices.

tistical analysis and consulting services for
global pharmaceutical organizations.

program with a semester of MBA classes.

required of them to run a private practice,
while still others are drawn to an opportunity
to explore a subject other than medicine.
Diverse as these motives are, however, one

"I feel that the way around this obstacle
is to get physicians involved in the decisionmaking processes of HMOs," she adds.

l

hadeus Grasela, PhD, PharmD, chief
executive officer and president of
Cognigen, says his company recruits students from the program because their

education and training provide them with a

students are seeking ways to provide the

"In general, I believe that the business aspect
of medicine should be understood

highest quality of care for their future patients.

by all physicians in order to help them de-

assets to his organization.

theme is echoed by all: Ultimately, these

"I have been hearing so much about the
changes that are going on in the medical
profession with regard to cost-cutting and
managed care, and it concerns me that this

18

A notable feature ofUB's MD/MBA pro-

Like manyofhercolleagues, Brenda Perez,

liver optimal care to their patients."

unique skills set-and perspective- that are
"The students have a background and

Medical students who earn their MBA

interest in both science and business, so they

have an opportunity to gain exposure to

bring a new vision of the future to the table,"
says Grasela. " In order for Cognigen to be

increased emphasis on the business aspect of

numerous subjects that are essential to a
practicing physician, such as finance,

medicine will lead to a disregard for the well -

accounting, information technology, man -

knowledge for decision making, we must

being of the patient, particularly when top

agement development and negotiations.

also develop paradigms for the use of

management consists of individuals with
little or no clinical experience," says MD/

Students can also receive training in health -

knowledge in strategic planning.

luffala Hysiciu

Spri11g

2002

care consulting, marketing, and entrepre-

successful, we must not only develop new

"Society desperately needs individuals

�trained in science and the use of knowledge
for decision making," he continues. "The

obtain a dual degree. "The year of business
training between the second and third year

directors looked upon his degree favorably
when he interviewed. "They were uniformly

lack of these individuals will become more

of medicine is well-timed," observes Michelle
Clark, Class of2003. "Without interrupting

impressed and encouraging," he says.

apparent as we move into the next phase of
increasing productivity based on the efficient use of technology.
"The [MD/MBA] students bring an enthusiasm and interest in global affairs that is
refreshing and stimulating. It is a pleasure to

rotations, we gain business knowledge after
having been introduced to medicine. This

Some MD/MBA students, however, have
received feedback about their participation
in the program that reflects deeply felt

allows us to begin applying our business
experience during our clinical years."

schisms in our society regarding the rela-

or the most part, students report that

Third-year student Perez, for example, has

f

tionship between medicine and business.

responses to their dual degree aspira-

been asked questions such as, "Why are you

tions have been positive. Daniel Avosso,

getting a business degree, only to go work for

For students, the opportunity to fluently

MD/MBA '01-the UB program 's first

an HMO?" And, "If you are interested in

transition between two well- integrated professional training environments is viewed

graduate-is currently working as an emergency medicine resident at Long Island's

as both an efficient and pragmatic way to

North Shore Hospital. He says residency

business, why not just go to business school?
You are taking the spot of someone who is
truly interested in practicing medicine."

work with such motivated-and motivating-individuals," Grasela adds.

I see aneed for physicians who are conversant in the business aspects of medicine to serve as an antidote to
this problem. It is they who can best reconcile the need for sound financial management with quality patient care.

�The students have abackground and interest in both science and business, so they bring
anew vision of the future to the table. In order for Cognigen to be successful, we must not
only develop new knowledge for decision making, we must also develop paradigms for the
use of knowledge in strategic planning.

About the author
Jennifer Wiler is a Colorado native who
has lived in NewYorkStateforthe past 10
years. After completing her undergraduate education at Colgate University
in Hamilton, New York, she worked at
Memorial Sloan-Kettering's Harlem
Women's Clinic

Some have even suggested to her that she is

adds. "By now, I feel it has become abun-

betraying the profession of medicine, ex-

dantly clear that medicine is not practiced in

pressing the opinion that "there is no place

a vacuum-it must be understood within
the context of its environment, part of

in medicine for business."
Fortunately, many physicians and students

which includes our market economy."

and then on Wall
Street as an assistant securities

do appreciate the critical role that business

Students in UB's new MD/MBA program

analyst. She has

now plays in medicine, and they recognize the

are delighted with the training they have

been an active

need for physicians who are both clinicians

received thus far and, as a group, we are

member of the

and managers. "Regardless of whether I later

anxious to see where our degrees will lead

decide to go into private practice, hospital

us. As we look to the future, we have no

administration or medical consulting, there-

doubts that throughout our careers as

medical school
community and served as president of the

alities of business have a daily and profound

physicians, we will strive to increase the

medical student body for 1999-2000. Upon

impact on how medicine is practiced in any of

quality of care delivered to our patients,

completion of her MD/MBA degree in 2003,

these settings," says MD/MBA student

while simultaneously acting as informed

she hopes to practice emergency medicine

Charlton Byun, Class of2003.

patient and physician advocates when busi-

"Understanding the basic concepts un-

ness issues enter the equation. This is not a

derlying the business world will likely be

formula for us to "make a lot of money," but

very helpful, if not essential, in any attempt
to deliver high-quality patient care," he

perhaps it is a way to enrich the healthcare
experience for our patients. &lt;t)

1501 Ferry Road , Grand Island , NY 14072

773-7063
z0

in New York City

l1ffale

Pbys i c i u

S priu g

200 2

and design programs for victims of domestic violence and sexual assauH. &lt;t)

�Alpha Omega Alpha
Honor Medical Society
White Family Memorial Fund Recipient

B

Alpha Omega Alpha is a national organization dedicated to supporting academic

rittany Lee Morse, Class of 2004, participated in a six-week rural family practice

excellence and perpetuating excellence

externship in Perry,

ew York, with support provided by the White Family

in the medical profession. It is the only

A native of LeRoy, New York, Morse currently resides in Corfu, New York, a

world; students are selected on the basis

Memorial Fund.

national medical honor society in the

rural town in Genesee County. Prior to entering the University at Buffalo's School of
Medicine and Biomedical Sciences, she attended SU Y College at Geneseo, where she

of scholarship and integrity.
Newly nominated Alpha Omega Alpha

earned a bachelor of science degree in biology. Lee's goal is to

members of the University at Buffalo's

practice medicine in an underserved rural community and, to

Epsilon Chapter from the Class of 2002

date, she has pursued a strong interest in family medicine.

inducted this spring are:

The White Family Memorial Fund was established in
2000 to memorialize Deborah A. White, MD '87, and her
husband, Christopher, and son, Adam, who died in a car
accident in 1999. It supports a summer internship for a firstor second-year student who is interested in pursuing a career

Garrick A. Applebee
Suzie Ariyaratana
Lily M. Belfi
linda J. Cuomo
Keely E. Dwyer-Matzky

in rural medicine.
"It was an honor to take part in achieving the goals set
forth by the White family, and I look forward to furthering
this effort in my career," says Morse. &lt;li)

Christopher M. Foresta
Anthony R. Mato
Christopher E. MuHy
Kathleen T. O'Donnell

-S. A.

UNGER

Aimee l. Stanislawski
Andrew B. Symons

Cra:z:iade Receives Sung Scholarship

Juliane M. Thurlow
Matthew S. Traugott

llison Graziade, Class of2005, is the first recipient of the john J. and janet H. Sung

A

Karen M. Weiss

Scholarship. Graziade, a native ofL1ttle Falls, New York, attended Umon College m
Schenectady, New York, where she majored in biology, with a minor in psychology.
"!am honored to receive the Sung Scholarship and be chosen out of the first-

Students from the Class of
20021nducted Last Spring:

year class to be the first recipient," says Graziade. "The Sungs are outstanding people,

Shaleen l. Belani

and I appreciate that they have provided a scholarship to recognize medical students.

Jennifer l. DeFazio

"In addition to the honor of receiving this award, the monetary gift is extremely
helpful considering the burden of financing a medical
education."
The Sung Scholarship is funded by a $1 million gift to the
University at Buffalo School of Medicine and Biomedical Sciences by John and Janet Sung, who came to the United States
from Korea in 1972 with only $200 to complete their education.
At the time, they had two dreams: to financially assist other
deserving students to attain their educational goals and to
establish a renowned clinic in radiology, both of which have
&lt;li)
been realized.

David M. Krakowski
Brian J. Maim
Caryn E. Orr
Andrew P. Swan

Students from the Class of
20031nducted This Spring:
Esme E. Finlay
Alfred T. Frontera
Julie A. Gavin
Stephen D. Hess
Sara I. Kaprove
Natasha S. Manes
Richard G. Newell

�A

L

U

M

N

BY S.A. UNGER

ATribute to Orvan Hess
A pioneer in fetal·heart monitoring
opment that made it possible to keep a
continuous, accurate check on the unborn
University at Buffalo School of Medicine and Biomedical Sciences-and certainly one of the most
baby's heartbeat even when medical peraccomplished. Over the course of his career, which spanned more than 50 years at Yale-New Haven
sonnel
were unable to be in the room.
Hospital, Hess helped pioneer fetal-heart monitoring, was an early advocate for the return of natural
"The fetal cardiac electrical signals
childbirth methods and was instrumental in the first use of penicillin.
could then be monitored and transmitted
While not able to travel from his home in Connecticut to join us for last year's Spring Clinical
by radio signal to a distant receiver,"
Day and his 70th class reunion, Dr. Hess, age 95, was nonetheless with us in spirit.
explains Hess.
The following article is published as a tribute to Dr. Hess, whose many scientific accomplish·
While these early fetal-heart monitors
ments not only have earned him world renown in his field, but also a place of pride among his fellow
were crude by today's standards and
medical school alumni. - John J. Bodkin II, MD '76 Preside11t, Mediml Alumni Association
would eventually be replaced by ultrasound, their development by Hess and his
colleagues marked the beginning of the
field of fetal cardiology.
In large part due to his work in this
field,
Hess received the Scientific AchieveOLLOWI G GRADUATIO from
faint and difficult to isolate from the
the then-University of Buffalo mother's. As a result, physicians were forc- ment Award from the American Medical
School of Medicine in 1931 , ed to employ what he calls the "watch-and- Association in 1979.
Contributing to his receipt of this prestiOrvan Hess completed his in- wait-and-pray" method.
ternship and residency training
Watching and waiting, however, was gious award was the work he did following
at the New Haven Hospital in not Hess's style. Upon his return to Yale, World War II to usher in the renaissance of
natural childbirth, as well as
New Haven, Connecticut. In therefore, he teamed up
\VHI LE THESE EARLY
pioneering studies he led in
1936, he began a research fel- with Dr. Edward Hon, a
FETA
L·
H
EA
RT
MO
l'&lt;I
TORS
wound
healing of the uterlowship at Yale University postdoctoral fellow, to
WERE
C
R
t;
DE
BY
TODAY'S
us after a Cesarean section.
School of Medicine, where he address this problem. In
STANDARDS AN D WOULD
was named clinical instructor 1957, the two researchers
Hess's clinical judgEVENTUA LLY BE REment also proved presm 1937. Five years later, he left the uni- became the first in the
PLACED BY uLTRASOuND,
cient in 1942, when he
versity to serve as a surgeon during World world to monitor fetal THE I R
BY
was a catalyst for the first
War II as part of the evacuation hospital heart activity by continHESS AND H I S COLsuccessful clinical use of
attached to General George Patton's 2nd uously detecting and reLEAGUES
MARKED
THE
penicillin. He recalled the
cording
electrical
cardiac
Armored Division during the invasions
BEG
INNING
OF
THE
FIELD
circumstances
leading to
signals
indicating
the
of North Africa, Sicily and ormandy.
OF
FETAL
CARDIOLOGY.
this
milestone
in a 1999
In 1949, Hess returned to Yale Univer- condition of the unborn.
interview. "My associate,
sity as assistant clinical professor and re- The machine they develsumed work he had begun as a resident on oped was six-and-a-half feet tall and two Dr. A. Nowell Creadick, asked me to go
a way to electronically monitor fetal-heart feet wide, far from being portable or com- see Mrs. Anne Miller in the isolation unit
of New Haven Hospital. She was one of
activity before and during delivery. One of pact in a crowded delivery room.
Working in collaboration with Wasil our obstetrical patients, pregnant with her
the problems obstetricians faced at that
time was the inability to diagnose fetal Litvenko, chief of Yale Medical School's fourth child, when she contracted scarlet
distress during the critical period oflabor electronics laboratory in the 1960s, Hess fever from her youngest son and suffered a
and delivery.
devised a system of telemetering the fetal miscarriage, subsequently developing an
"The stethoscope just could not do the electrocardiogram and intrauterine pres- overwhelming bloodstream streptococcus
job," says Hess. The fetal heartbeat was sure during pregnancy and labor, a devel- infection. Doctors had done everything

Obstetrician/gynecologist and surgeon Orvan Hess, MD '31, is one of the oldest living alumni of the

DEVELOP~IEl'&lt;T

22

B

u II a I o Physician

Spri11g

2002

�possible, both surgically and medically. I
went to see her and knew she was dying.
" From the hospital I went to the Graduate Club to see her internist, Dr. John
Bumstead. I discovered he was upstairs in
the library, where he had fallen asleep
reading a newspaper. While I was waiting
for him to wake up, I sat and read the
latest Reader's Digest, in which there was
an article called " Germ Killers from
Earth, " about the use of a soil bacteria to
kill streptococcal infection in animals.
"When I spoke to Dr. Bumstead, I asked if anything more could be done for
Mrs. Miller, and I said, 'Wouldn't it be
wonderful if we had something like this
gramicidin mentioned in the Reader's
Digest?' This suggestion prompted Dr.
Bumstead to talk with his neighbor, John
Fulton, a professor of physiology at the

Drvan Hess, MD '31, says he is still fascinated with technology and the excitement of medical progress.

Yale School of Medicine, who had worked
in England with Howard Florey, who was
studying penicillin. Dr. Bumstead asked
Fulton if he could contact Florey and possibly obtain some of the scarce penicillin.
Fulton agreed and Anne Miller received
her first injection on March 14, 1942.

By the next day, her fever had broken. "
Today, Hess says: "I am more convinced than ever that technology can be
applied to medical practice without sacrificing humanism or our sacred patientphysician relationship. " (Ji)

.
0

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Spring

2002

lu ff a l o Phy sici lD

23

�IMAGINATION
PET

CENTER MARKS
TENTH ANNIVERSARY
BvALAN H.

I

LOCKWOOD.

MD

n November 2001, the University at Buffalo-Veterans Affairs' Positron Emission Tomography (PET) Center celebrated its
1Oth anniversary. In recognition of this milestone-and the notable accomplishments emanating from this center since its
inception-we asked Alan Lockwood, MD, director of operations, to write an article highlighting work that has taken

place at the facility over the past decade and to preview the direction in which he sees this research moving in the years ahead.
Lockwood, a UB professor of neurology, nuclear medicine, and communicative disorders and sciences, has won international
acclaim for PET studies he has led in recent years on the origins of tinnitus. These studies-conducted in collaboration with
Richard Salvi, PhD, UB professor of communicative disorders and sciences and clinical professor of otolaryngology and neurology,
and Robert Burkard, PhD, also a UB professor of communicative disorders and sciences-were the first to show that tinnitus
sounds originate in the brain, not in the cochlea, as scientists previously thought.
Following the announcement of these findings in January 1998, Lockwood received a steady stream of calls from news reporters
around the world. The study was featured on NBC's Today Show and reported on in the New York Times, the Los Angeles Times
and Time magazine, among other publications.
As Lockwood reports here, a number of other studies conducted at the UB- VA PET Center over the past ten years have
uncovered intriguing findings that demonstrate what can be accomplished when talented researchers from a broad range of
disciplines combine the science of imaging with the power of imagination.
S. A.

lJ~GER

EDITOR

2 ..

Ia f fa I o Physic i aa

Spri 11 g

2 00 2

�hat do tinnitus ,
heart attacks, cancer and the past
tense of English
verbs all have in
common? These
seemingly disparate topics have all been the focus of
research studies performed in the UB-VA
Positron Emission Tomography Center.
To mark its first ten years of operation, center investigators described their accomplishments in an Anniversary Symposium
held last

ovember.

Positron emission tomography, better
known as PET, is a technique that captures
basic life processes in a pictorial format. The
PET image is, in essence, a snapshot of
how the body functions from a biochemical
or physiological perspective. By contrast,
X-rays, computerized tomography (CT)
scans and magnetic resonance images
(MRI) typically portray anatomical information. This ability of PET images to
photograph life processes has led to important advances in research and patient care.
PET imaging begins with knowledge of
how a critical body system works. For example, the brain uses glucose, a sugar, as its
only source of energy. Since the brain can't
store glucose, it depends on the rest of the
body to deliver this vital compound on a
second-to-second basis via the bloodstream. In a very real sense, the brain is like
the engine of a car-it does lots of work,
but it depends on the constant delivery of
fuel to be able to function. By measuring
how much glucose the brain is using or how
much blood is flowing to the brain, it is
possible to deduce how hard the brain is
working. In other words, measurements of
glucose use and blood flow yield impor-

ALA" LOCKWOOD,

~D

largest medical cyclotrons in the United

subject or a patient undergoing a PET scan,

inject a tracer (isotope) and take pictures.
Behind this fa&lt;yade, however, there is a large
team of technicians.
Since the isotopes used in PET all have
very short half-lives (the time it takes for the
activity to fall by 50 percent ), all the tracers

the process is deceptively simple. All they

are synthesized just before they are used.

need do is to lie down with their head in the

This step takes place on UB's South Cam-

The most commonly used PET tracers

camera while members of the PET team

pus, in Parker Hall, home of one of the

are fluorodeoxyglucose (FDG ) and water.

tant information about how normal or
healthy a part of the brain might be or how
hard it is working.
From the perspective of a research

States. After the tracer is synthesized, it is
whisked over to Buffalo's VA medical center, some 3,000 feet away, via an underground pneumatic transport system. At the
VA, images are produced and then analyzed
using sophisticated computer software.

S pri ng

2002

lullalo Physicin

25

�I111aging and I MAG

CONTINUED

I NAT I

FROM PAGE

o

N

25

The metabolism of FDG is very similar to
glucose metabolism, with one important
exception: One of the key enzymes for
glucose metabolism can't act on FDG, so
the metabolic process stops at this step.
This traps the tracer, which allows the PET
camera to image its distribution in the
body. The amount of trapped FDG is proportional to the amount of glucose that is
being metabolized. High amounts of the
tracer are an indication of a high glucose
metabolic rate, and vice versa.
Blood flow is measured in studies that
use labeled water as a tracer. These studies
are complicated by the fact that the halflife of the water used is only 123 seconds,
SO every tWO minutes the amount of

jAMES fALLAVOLLITA , MD, left, AND jOHN CANTY, MD

tracer is reduced by half. As a result, these
studies require close cooperation be-

parts of the brain become active or inac-

energy to bring this complex projecL

tween the cyclotron operators and chem-

tive. Thus, a typical brain mapping study

to fruition. After securing critical support

ists who make the labeled oxygen and

includes scans done at rest and scans done

from the community in the form of a

convert it into water and the technolo-

as a subject performs a series of increasingly

substantial grant from the James H.
Cummings Foundation, Prezio and his
associates convinced UB and the VA that
the center would become a vital element

"THE STUDIES IN THE

UB-VA PET

in their quest for excellence. Several years
CENTER SERVE AS A MODEL

FOR INTERDISCIPLINARY COLLABORATION. THE OPPORTUNITY TO
WORK WITH COLLEAGUES WITH VASTLY DIFFERENT BACKGROUNDS

of planning, construction and recruitment of staff led to the first PET scan in
October 1991. Since then, thousands of
patients have been scanned and more than

HAS BEEN ONE OF THE MOST REWARDING ASPECTS OF MY JOB AS
DIRECTOR OF PET OPERATIONS."

- ALAN LOCKWOOD,

MD

$4 million has been awarded to support

research in the center. The Anniversary
Symposium was planned to highlight
major research accomplishments.

gists and investigators who use the labeled

complex tasks. By subtracting the resting-

water in a PET study.

state scan from the scan done while the

Although blood-flow studies using
labeled water are complex, they have been
the key to some of the most important
work done in the UB- VA PET Center.
By comparing the pattern of blood

26

brain is at work, it is possible to identify the
parts of the brain that mediate the task.
Using this basic strategy, center investigators have made important discoveries
that have identified the brain regions that

flow at rest with the pattern during the

mediate tinnitus and those that we use

performance of a specific task, it is pos-

when we form the past tense of a verb.

sible to identify the regions of the brain

The Anniversary Symposium began

that perform the task. This strategy works

with a brief history of the UB-VA PET

because the brain can' t store energy. It

Center, which reviewed how joseph Prezio,

depends on instantaneous changes in the

MD, the then-chair of the UB Department

delivery of glucose and oxygen as various

of Nuclear Medicine, had the vision and

l1ffalo Physician

Spri11 g

2 00 2

BETTER CARE FOR HEART DISEASE

Heart disease is a major cause of death and
disability among Americans and is a particularly serious problem in Western

ew

York. John Canty, MD, and James
Fallavollita, MD, from the UB Department
of Medicine, have used FDG PET to define
and study "hibernation" in the heart muscle. Hibernating muscle is still alive but does
not function properly, causing the heart to
pump inefficiently. A better understanding
of this process will lead to improved care
for patients with coronary artery disease.

�Since PET cameras are

thesizes that some of these new connec-

nearly noiseless, unlike

tions are responsible for this false sense of

magnetic resonance scan-

ringing in the ears.

ners, PET is the ideal tool

These studies are complemented by

for studies of hearing dis-

studies of the normal auditory systems

orders. A research team

performed by the tinnitus team and inves-

consisting of myself, Robert

tigations of other aspects of the normal

Burkard, PhD, and Richard

auditory system spearheaded by Ann

Salvi, PhD, from the UB

Eddins, PhD, associate professor in the UB

Departments of Communi-

Department of Communicative Disorders

cative Disorders and Sci-

and Sciences.

ences, Neurology and Nuclear Medicine, have identi-

L ANG UAG E AND GENDER

fied and mapped the brain
regions that mediate tinnitus, the false perception of a
sound in the absence of an
environmental source. This
problem plagues millions
and is almost always associated with hearing loss. By
studying a group of patients
who are able to modulate
the loudness of their tinnitus, this investigative team
was able to pinpoint the
auditory cortex as the site
ROBERT BURKARD. PHD.

front. A~D

RICHARD SALVI. PHD

DI FFE RENTIATING LESIONS

Every year, doctors must tell some of their
patients that a routine chest X-ray reveals

where tinnitus originates.

In related studies, these
researchers have found that hearing loss
leads to a reorganization of the auditory

jeri jaeger, PhD, from the UB Department
of Linguistics, directed studies that show
how the brain forms the past tense of
English verbs. By mapping brain regions
activated by forming the past tense of regular verbs (e.g., walk/walked), irregular
verbs (run/ran) and clusters of letters that
look like words (brep/brepped), jaeger and
her colleagues concluded that the brain
minimizes word storage needs by using
rules to form the regular past tense and a
dictionary look-up strategy for irregular
verbs. In addition, the brains of men and
women perform these tasks differently:
Women use both brain hemispheres to
form a past tense, whereas men use the left
hemisphere.

pathways in the brain. The team hypo-

a spot or nodule in the lung. Not all of
these nodules are cancerous, but that is
always the main concern. Since cancerous
cells use large amounts of glucose, FDG
PET scans can help differentiate the cancers from benign lesions, without the need
to perform invasive surgical procedures.
Syed Husain, MD, a nuclear medicine physician at the VA, is the Buffalo site investigator in a nationwide cooperative study
designed to better characterize the ability
of PET to differentiate malignant nodules
in the lung from those that are benign.

B RA I N R EGIONS AN D T I NN ITUS

Studies of the auditory system, particularly investigations of tinnitus, have been
a major focus of research in the center.

JERI jAEGER. PHD

Spring

2002

8 u If a I o Ph JS i ci a n

27

�Jmagin,~

and I

M A G I N AT I 0 N

anatomy relationships revealed by MRI scans, and
brain physiology revealed
by PET.
CusTOMIZING
CANCER CARE

Hani Abdel-Nabi, MD,
PhD, chair of UB' s Department of
uclear
Medicine, and his associates from otolaryngology
and surgery have made
important contributions
to the emerging field of
PET oncology. In patients
with cancer PET often
yields information about
the extent of a patient's
disease with images that
are more sensitive and
specific than images obtained with other methods. PET scans allow a
cancer patient' s physicians to plan treatments

RALPH BE!';EDICT, MD

THE IMPACT OF MULTIPLE SCLEROSIS ON AUDITORY ATTENTION

Attention is a term psychologists use to describe the process of focusing brain resources on a given task. The neural systems
that mediate visual attention have been
studied extensively in other centers. Ralph
Benedict, MD, and his colleagues from the
UB Department of Neurology have developed a task that tests auditory attention. Not
surprisingly, some of the same regions of the
brain are used by both the auditory and the
visual systems. In a recent extension of those
studies, Benedict and his colleagues have
studied attention in patients with multiple
sclerosis, They have found that there are
changes in the auditory attention pathways
that appear to be the consequence of the
disease, and they have begun to show how
the brains of these patients are reorganized
in an attempt to compensate for the lesions
in their brains. This team is also collaborating with Rohit Bakshi, MD, from the UB
Department of eurology, to study brain

that are the most effective while avoiding
high-morbidity surgical procedures that
would be ineffective. This is a win-win
situation that helps the patient, the physician and the healthcare system by reducing costs.

Left to right,

laflalo Physician

S prin g

20 0 2

D THE AUDITORY SYSTEM

Salvi and Burkard and I have teamed up
with investigators from the University of
Rochester to study aging in the auditory
system. Studies by this group have shown
that aging has an effect on the central auditory system that is independent of the hearing loss common among the elderly.
MIGRAI E PHYsiOLOGY AND TREATMENT

Headache is one of the most common problems faced by Americans and is a frequent
cause of lost time from work. Edward
Bednarczyk, PharmD, of the UB Departments of Nuclear Medicine and Pharmacy
Practice, and his associates have tackled this
problem in a series of studies of spontaneous migraine headaches. They augmented
these investigations by using a model of
migraine in which tiny amounts of nitroglycerine are given to migraine patients as
they are scanned. To complement these
studies, the team is evaluating drugs designed to prevent headaches.
PET AND

EUROPSYCHOLOGY

The symposium was rounded out by showing how PET imaging can be integrated with
psychological testing. In separate studies
that have probed the effects of head injury
and the effects of liver failure on brain

HA:-11 ABDEL-N'ABI, MD, PHD. EDWARD BEDNARCZYK. PHARMD, AND

SYED SAJID HUSAIN. MD

28

AGING A

�function, my colleagues and I have shown
that specific brain regions are associated
with the performance of some of the most
common tests used by psychologists.

IN ANOTHER STUDY ON THE HORIZON, CENTER INVESTIGATORS WILL BEGIN COLLABORATION WITH COLLEAGUES

UB

RESEARCH PROJECTS ON THE HORIZON

FROM THE

DEPARTMENTS OF NEUROLOGY AND

The studies in the UB-VA PET Center serve

NEUROSURGERY IN A NATIONWIDE EFFORT TO IDENTIFY

as a model for interdisciplinary collaboration. The opportunity to work with col-

STROKE PATIENTS WHO WOULD BENEFIT FROM SURGERY

leagues with vastly different backgrounds

DESIGNED TO BYPASS BLOCKED ARTERIES TO THE BRAIN.

has been one of the most rewarding aspects
of my job as director of PET Operations.
Clearly, none of the research conductstudy of multiple sclerosis, where inves-

ed in the center would have been possible
without grants from sources that are as

a nationwide effort to identify stroke
patients who would benefit from surgery

tigators from the Jacobs

diverse as the expertise of the center' s sci-

designed to bypass blocked arteries to

Institute are studying genetic markers in

entists. These include several branches of

the brain.

these patients.

eurological

ational Institutes of Health, the

Also, Canty and Michael Haka, the

For these reasons and more, I believe

Department of Veterans Affairs, the De-

center's chief radiochemist, have recently

that the next decade will be even more

partment of Education , the American
Heart Association, a number of pharma-

teamed up to study the nerve supply to the

exciting than the first for the UB- VA

heart using a novel

PET Center.

ceutical companies, Siemens Medical

tracer, hydroxy-

the

Systems, and a variety of foundations,

ephedrine. Canty

most notably the James H . Cummings

suspects that an

Foundation of Buffalo.
In looking toward the next decade, I

abnormal nerve

PET Center. Several new initiatives are

supply to the heart
may be an important factor in sud-

under way that will expand its research

den cardiac death.

program .
In a new half- million-dollar grant from

I also anticipate that the ini-

feel the best is yet to come for the UB-VA

the VA Merit Review program, Burkard

tiatives growing

and I, along with other collaborators, will

out of the Buffalo

study the effects of background noise on

Center of Excel-

the auditory system. Merging recordings

lence in Bioinfor-

of brainwave activity with PET is a cen-

matics (see related

tral aspect of this research. It takes about a
minute for a PET camera to image brain

article on page 14)
will enable PET

activity. This is an eternity, in terms of
neural activity, where communications

expand their stud-

investigators to

between nerve cells occur in thousandths of

ies and enhance

a second. By combining PET images that
show where something happens with

the value of their
PET data by creating links with in-

electrophysiological recordings that show

4D

when something happens, we hope to
improve our ability to probe brain function.
In another study on th e hori zon, center

vestigators study-

investigators will begin collaboration

liminary steps in

with colleagues from the UB Departments of eurology and Neurosurgery in

been taken in the

ing genomics and
proteomics. Prethis direction have

Spri11g 2002

Bu ffalo Physician

29

�PATHWAYS

NEws ABOUT UB's ScHooL oF MEDICINE
AND BIOMEDICAL SciENCES AND ITS
ALUMNI, FACULTY, STUDENTS AND STAFF

IN THIS CAPACITY
[LAYCHOCK] WILL
PLAY A LEAD ROLE IN
DETERMINING WHAT
RESEARCH WILL BE
CONDUCTED AT UB's
SCHOOL OF MEDICINE
AND BIOMEDICAL
SCIENCES AND HOW
RESOURCES WILL BE
ALLOCATED FOR THIS
RESEARCH.

30

I u I I a I o Physician

logy from Brooklyn College,
Laychock to Lead
Research Efforts
City University of New York,
Suzanne G. Laychock, PhD, and a doctorate in pharmacolprofessor and associate chair ogy from the Medical College
of the Department of Pharm- of Virginia. In 1990, she was
acology and Toxicology in the selected as the outstanding
University at Buffalo
STAR alumnus at
School of Medicine
the Medical College
and Biomedical Sciof Virginia.
ences, has been apLaychock serves
pointed senior associas associate editor
ate dean for research
of Lipids and was
and biomedical eduassociate editor of
cation at the school.
Endocrine Research
In this capacity, LAY C HO C K
from 1992 to 200 l.
she will play a lead
She has also served
role in determining what re- as field editor for the Journal
search will be conducted at of Pharmacology and ExperiUB's School of Medicine and mental Therapeutics, and on
Biomedical Sciences and how the editorial board of the
resources will be allocated for journal Diabetes.
this research. She will also
Laychock's research into
oversee the recruitment and endocrine pharmacology with
hiring of new research faculty.
an emphasis on the cellular
Laychock, a member of the mechanisms regulating insuUB faculty since 1989, is an lin secretion has been funded
accomplished researcher with since 1979.
more than 80 publications. In
She is a member of several
addition to serving as associ- professional societies, includate chair of her department ing the American Diabetes
since 1995, she was codirector Association, the American
of its Institute for Research Society for Pharmacology and
and Education on Women and Experimental Therapeutics
Gender. She holds bachelor's and the Endocrine Society.
and master's degrees in bio- - LOIS BA K ER

S p ri n g

2 00 2

Holm Named Senior
Vice Provost
Bruce A. Holm, PhD, has been
named a senior vice provost at
the University at Buffalo,
where he will serve as the point
person on many of the
university's high-technology/
biotechnology projects.
In this role, Holm, who formerly served as UB's senior
associate vice president for
health affairs, will represent
Provost Elizabeth D. Capaldi
in a variety of capacities.
He will be the chief administrator in the provost's office
for the Buffalo Center of Excellence in Bioinformatics (see
related article on page 14), the
Strategically Targeted Academic Research (STAR) Center for Disease Modeling and
Therapy Discovery, and the
Center for Advanced Biomedical and Bioengineering Tech nologies (CAT). He also will
participate in the development
of an institute in biomedical
engineering at UB and collaborate with administrators in the
Office of Science, Technology
and Economic Outreach.
"Dr. Holm will work closely
with our academic partners-

�Roswell Park
Cancer Institute
and the Hauptman-Woodward Medical
Research Institute-and with
our
corporate
HOLM
partners, the
local business community
and faculty and deans as these
projects move forward," says
Capaldi. "He also will work to
develop further external relations and scientific and corporate partnerships."
Holm holds faculty positions as professor of pediatrics,
pharmacology and toxicology,
and gynecology-obstetrics, and
also serves as associate senior
vice president for scientific
affairs at Roswell Park. He is
principal investigator of the
STAR center, as well as several
other large awards, including
those from the Markey Trust
and the Howard Hughes Medical Institute. In addition, he
maintains an active research
program that has attracted
millions of dollars in grant
awards to VB.
- S U E WUETC HER

Mihalko to Direct CAT
William M. Mihalko, MD, has
been named executive director
of the University at Buffalo's
Center for Advanced Technology (CAT) by Provost Elizabeth D. Capaldi.
Mihalko is an associate professor in the Department of
Orthopaedics in UB's School of
Medicine and Biomedical Sciences and research director in

the Department of Orthopaedic Surgery. Holding both
medical and biomechanicalengineering degrees, he serves
as the head of arthroplasty at
the Erie County Medical Center
and is on the medical staffs
of Kaleida Health's Millard
Fillmore hospitals, Buffalo
General Hospital and Children's Hospital of Buffalo.
"We are delighted to have
someone of Dr. Mihalko's
caliber to direct the CAT,"
Capaldi said in making the announcement. "He is a bioengineer with an active research
and clinical program who will
provide superb leadership in
evaluating and developing
biodevices for commercialization in Western New York."
Mihalko ' s appointment
comes at a time when the
CAT- barely three-quarters
into its first official year-is already making strides in its
main mission: to provide funding to innovations in biopharmaceuticals and in biomedical
devices that are close to commercialization. ew York State
Governor George E. Pataki announced creation of the CAT
and $1 million in funding for its
first year of operation last May.
"Dr. Mihalko's expertise
bioengineering represents
an area in
which we' re
very strong,"
says Robert
Genco, DDS,
PhD, a vice
provost
and head of
UB's Office
MIHALKO

111

Hayes Honored by the AMA
Maxine Hayes, MD '73, assistant secretary of Community
and Family Health for the Washington State Department of
Health and the recipient of UB's 2000 Stockton Kimball
Award, has received the American Medical Association's
2002 Nathan Davis Award in the category of Career Public
Servant at the State Level. She was nominated for the
award by Mary Selecky, Secretary of Health, Washington
State Department of Health.
In announcing the award, the AMA stated: "The awards,
presented to local, state and federal career and elected
government officials, were established by the AMA in
1989 and are truly one of the most prestigious forms of
recognition for outstanding public service in the advancement of public health .... The caliber of our nominees [this
year) was truly inspiring, and your selection from such
an impressive
group certainly
speaks volumes
in recognizing
the dedication
and diligence
of your public
service."
Hayes, who
also holds a
master's degree
in public health
from Harvard
University, is a
nationally known

HAYES

pediatrician
who, among other things, has strongly advocated for
universal health and dental care for children and the
elimination of tobacco use among our youth.
The award was presented to Hayes on January 29,
2002, at a dinner in Washington, D.C., that was attended
by officers of the AMA, as well as by members of Congress
and administration officials. &lt;t)
-S. A. UNGER

Spri11g

20 0 2

I u If a I o Physician

31

�PATHWAYS

MIHALKO's APPOINTMENT COMES AT A TIME WHEN THE

CAT ...

IS ALREADY MAKING STRIDES IN

ITS MAIN MISSION: TO PROVIDE FUNDING TO INNOVATIONS IN BIOPHARMACEUTICALS AND IN
BIOMEDICAL DEVICES THAT ARE CLOSE TO COMMERCIALIZATION.

of Science, Technology and
Economic Outreach. Previously director of the CAT, Genco
is a SU Y Distinguished Professor and chair of the Department of Oral Biology in the
School of Dental Medicine.
After completing his residency at the UB Department
of Orthopaedic Surgery,
Mihalko completed an Adult
Reconstructive Surgery Fellowship at the Missouri Bone
and Joint Center. He earned
his medical degree, as well as a
doctorate in biomechanical
engineering, from the Medical
College of Virginia.
He is the recipient of an
award from the Buffalo Orthopaedic Research and Education
Foundation for Outstanding
Orthopaedic Research during
Residency, and the American
Medical Association's Physician Recognition Award and,
with colleagues, the Knee

Society's Ranawat Award for
research on knee-joint stability.
- ELLE N GOLDBAUM

Baker and Coldbaum
Win Writing Awards
Lois Baker and Ellen Goldbaum, senior editors in the
University at Buffalo's News
Services unit and regular contributors to Buffalo Physician
received a Gold Medal in
the research, medicine and
science writing category in
the 200 l Council for the Advancement and Support of
Education (CASE) District II
Accolades competition. The
silver medal in this category
was awarded to the University
of Toronto and the bronze to
Princeton University.
Baker ' s submissions included a series of articles on
research being conducted by
Frederick Sachs, PhD, UB
professor of physiology and
biophysics, in which he has

shown how a
protein isolated from
the venom
of a Chilean
tarantula
holds promise as the basis for new

GOLDB A UM

drugs for preventing atrial fibrillation. Also judged to be
excellent were articles she
wrote on research conducted
by Herbert Schue!, PhD, UB
professor of pathology and
anatomical sciences, that elucidates an internal cannabinoid-signaling system that
regulates human sperm fertilization potential; and a
study by Ad nan Qureshi, MD,
UB assistant professor of
neurosurgery, which found a
lack of preventive efforts to
avert second heart attacks.
Goldbaum was singled out
for her article on work being

conducted
at UB by
Thenkurussi
Kesavadas,
PhD, assistant professor of mechanical and
BAKER
aerospace
engineering, who is collaborating with researchers in
UB ' s School of Medicine and
Biomedical Sciences to develop a virtual palpation glove.
Baker and Goldbaum's
medical-science reporting
also won Bronze Medals in
the national 200 l and 2002
CASE Circle of Excellence
Awards competitions.
-S. A .

Rokitka Named to
Editorial Post
Mary Anne Rokitka, PhD,
clinical associate professor of
physiology, assistant dean,
and director of undergraduate studies in the University
at Buffalo's School of Medicine and Biomedical Sciences, has been named an associate editor for Advances in
Physiology Education. The
peer-reviewed journal, a publication of the American
Physiological Society, is dedicated to the improvement of
teaching and learning physiology and to the advancement
of physiology as a teaching
profession. 4D
- S. A.

3 2

luttale Physician

Spring

2002

UNG ER

U NGE R

�Roswell Park Cancer Institute IRPCII was founded in 1898 and is the nation's first cancer research,
treatment and education center and the only National Cancer Institute-designated comprehensive
cancer center in Western New York. The cancer center is a teaching and research affiliate of the UB
School of Medicine and Biomedical Sciences, and many faculty at RPCI hold joint appointments at UB.
Over the past two years, RPCI has developed and implemented a strategic plan to aggressively
recruit new clinical and scientific talent to the cancer center. In January 2002 RPCI president and
CEO David Hohn, MD, held a press conference to summarize the successful results of this effort. He also
took the opportunity to announce the recent recruitment of two national leaders in the field of oncology,
Donald L. Trump, MD, and Candace S. Johnson, PhD.
Below are brief profiles of Trump, Johnson and other faculty who have joined RPCI and UB's
School of Medicine and Biomedical Sciences in leadership positions since 2000.

Donald L. Trump, MD

Senwr V&gt;ce President for
Clinical Researrh
Chazr, Department of Medicim
Copnncipnl Jnvestzgator,
Cancer Center Support Grant
Roswell Pnrk Cancer Institute
Donald L. Trump, MD, joined
the faculty of RPCI in February
2002 as senior vice president for
clinical research, chair of the
Department of Medicine, and
coprincipal investigator of the
Cancer Center Support Grant.
Trump earned his
medical degree from
The Johns Hopkins
University School of
Medicine, Baltimore, in
1970 . From 1970 to
1975 he completed an
internship and resiTR U MP
dency training in medicine at The Johns Hopkins
Hospital, along with a fellowship in oncology at The Johns
Hopkins Oncology Center.
Most recently, Trump served as deputy director of clinical
investigations at the University
of Pittsburgh Cancer Institute
(UPCI), where he had primary
responsibility for directing the

clinical and translational research activities, and as chief
of the Division of Hematology and Oncology in the Department of Medicine and
professor of medicine and
urology at the University of
Pittsburgh Medical Center.
Trump is a Diplomate of
the American Board of Internal Medicine, with subspecialty
boards in medical oncology,
and a Fellow of the American
College of Physicians. His research interests include innovative clinical trials
and chemoprevention studies in prostate cancer; antitumor mechanisms and
therapeutic effects of
vitamin D; and feasibility studies on retinoid treatment in
emphysema. He is a member of
the Eastern Cooperative Oncology Group and a principal
investigator or coprincipal investigator on several National
Cancer Institute-funded trials.
Trump is the recipient of
numerous awards and honors
including the 2001 Pittsburgh

Science, which recognizes those
individuals who dedicate their
services to making Pittsburgh a
better place to live; multiple citations in Best Doctors in

America; and, yearly since 1998,
awards from the Association for
the Cure of Cancer of the Prostate (CaP CURE) for his research
on the role of vitamin D in the
treatment of prostate cancer.
Trump serves as secretary/
treasurer of the American
Society of Clinical Oncology
and is a member of many professional societies. He is also
reviewer and/or member of the
editorial board of several
prestigious journals, such as
the New England foumal of
Medicine, and the Journal ofthe
National Cancer Institute.

Gentzke &amp;
sociates,

Inc.

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.\ la n age mcnt
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President and CEO Glenn Gentzke
and Chief Investment Strategist
Chris King

Fcc- Based 1\ ssrt
.\la nagcm cnt

UB Commons
520 Lee Entrance

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Suite 205

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Tel: (716) 639-G475

Certified Qflicf.JJooks
Profrss iona l Ackiso rs

www.gentzke.com

Vectors Person of the Year in

Sp rin g

2 0 0 2

l alfal1 Physiein

33

�PATHWAYS

Candace S . .lohnson, PhD

Senior ~'icc Pres1dwt {or
Translational Research
Semor Member, Department of
Pharmacology and Therapeutics
Roswell Park Cancer Institute

Candace S. Johnson, PhD,
joined the faculty of RPCI in
February 2002 as senior vice
president for translational research and senior faculty member of the Department of Pharmacology and Therapeutics.
Johnson earned her doctoral
degree in immunology from
Ohio State University in 1977.
From 1977 to 1981 she completed research
and postdoctoral
fellowships in
immunology/cell
biology at the
Michigan Cancer
Foundation in
Detroit. Most recently, Johnson
jOHNSON
served as deputy
director of basic research at
the University of Pittsburgh
Cancer Institute and as professor of pharmacology and
medicine at the University of
Pittsburgh School of Medicine.
Johnson's research interests
include translational research
to facilitate the efficient application of promising laboratory
findings in clinical studies;
preclinical design and development of more effective therapeutic approaches to cancer
using highly characterized tumor models; and mechanisms
of vitamin D-mediated antiproliferativeeffects either alone
or in combination with other
cytotoxic agents.

34

luflal1

Pbysiciaa

Johnson is a member of the
National Institutes of Health
Reviewers Reserve and the National Cancer Institute Review
Group Subcommittee A-Cancer
Center (Parent Committee). She
is also a member the editorial
board of Oncology Reports,
Molecular Cancer Therapeutics,
and Molecular PIUlrmacology.
Michael C. Brattain, PhD

Chair, Department of Phannacology and Therapeutics
Basic Science Director, Cancer
Center Support Grant
Roswell Park Cancer Institute

Michael Brattain, PhD, joined
RPCI in 2001 as chair of the
Department of Pharmacology
and Therapeutics and basicscience director of the Cancer
Center Support Grant.
Brattain, who earned his
doctoral degree in biochemistry from Rutgers University in
1974, carne to RPCI from the
San Antonio Cancer Institute,
a National Cancer Institutedesignated comprehensive
cancer center, where he was associate director for basic research. At the same time, he
served as professor of surgery
at the University of Texas
Health Science Center in San
Antonio.
Over the years, Brattain has
held several research, administrative and academic positions,
including professor of biochemistry and molecular biology at the Medical College of
Ohio; director of the BristolBaylor Laboratory Division,
Baylor College of Medicine;
and director of molecular and

Spring

2002

cellular
biology,
anticancer
research, at
BristolM y e r s
Squibb, Inc.
He serves on
BRATTAIN
the editorial
board of Cancer Research, International Journal of Oncology,
and Oncology Research.
Brattain is a member of the
American Association for Cancer Research, the American Association of Pathologists, and
the Metabolic Pathology Study
Section of the National Institutes of Health. His research in
signal transduction pathways
in breast and colon cancer has
attracted major funding from
the National Cancer Institute,
and he has created a broad
national network of scientific
collaborations.
.lohn K. Cowell, PhD, DSC

Chmr, Department of
Cancer Genetics
Roswell Park Cancer Institute
Professor, Cellular and
Molecular Biology Program
Roswell Park Graduate
Dll'lsion, University at Buffalo

John K. Cowell, PhD, DSc,
joined the staff of RPCI in
2000 as chair of the Department of Cancer Genetics. He
also is professor of the Cellular and Molecular Biology
Program in the Roswell Park
Graduate Division, University
at Buffalo.
Cowell earned his doctoral
degree in genetics from

Sheffield University (UK) in
1978 and completed research
fellowship training in the Department of Cellular Pathology at the Imperial Cancer
Research Fund (London, UK)
in 1981. He was honored with a
doctor of science degree from
Sheffield University
in 1993.
Cowell came to
RPCI from the
Cleveland Clinic
Foundation (CCF),
Lerner Research
Institute, where he
had served as direc- CowELL
tor of the Center for
Molecular Genetics since 1995.
He also had a joint appointment at the CCF Cancer Center
and was a CCF professor of
clinical chemistry at Cleveland
State University.
Cowell's research interests
include molecular genetics of
cancer and cancer predisposition, molecular analysis of
neuroblastoma, molecular
genetic changes in leukemia,
and genetic analysis of brain
tumors and breast cancer.
Soldano Ferrone, MD, PhD

Cha1r, Department of
Immunology
Roswell Park Cmzcer Institute
Professor, Aficrolnology
University at BujJalo

Soldano Ferrone, MD, PhD,
joined the staff of RPCI in
1999 as chair of the Department of Immunology. He also
is professor of microbiology at
the University at Buffalo.
Ferrone earned his medical

�degree at the Medical School,
University of Milan (Italy) in
1964, and his doctorate in hematology at the University of
Milan in 1971.
He was a member of the
faculty of the Department of
Medicine at the University of
Milan from 1964 to 1965; the
Department of Experimental
Pathology at Scripps Clinic
and Research Foundation (La
Jolla, California) from 1971 to
1981; the Department of Pathology at Columbia University from 1981 to 1983; and
chair of the Department of
Microbiology and Immuno-

logy at New York Medical
College (Valhalla, New York)
from 1983 to 1999.
Ferrone's laboratory research program focuses on
developing approaches to
counter the multiple mechanisms used by human melanoma cells to escape immune
recognition and destruction,
and on designing a strategy to
target humoral and cellular
immunity to malignant lesions
in patients with melanoma.
Ferrone is a member of the
American Association of Immunologists, the American
Association for Cancer Re-

search, and the Transplantation Society.
Currently, he is a member
of the Biological Resources
Branch Oversight Committee
and of Subcommittee F (Manpower and Training) of the
National Cancer Institute Initial Review Group.
Ferrone has been issued
patents on "Anti-idiotypic
Monoclonal Antibodies MK223MelanomaAntibody763.74"
and on "Anti-idiotypic Monoclonal Antibodies for Treatment of Melanoma."
He was honored with the
Alexander Von Humboldt

Award, Senior
Distinguished
U.S. Scientist
Award, Germany, in 1997.
Ferrone has
authored or coauthored more FERRONE
than 700 journal publications, book chapters and abstracts.
He serves on the editorial
board of the International
Journal of Oncology, Journal of
Im111unology, Journal of l111munothernpy, Tissue Antigens,
and Vaccine Research.

GENESEE
HEARING SERVICES

THE AUDIOLOGY
CENTER

61 Wehrle Drive
(Near Harlem)
Amherst 14225

630 Orchard Park Rd.
(Near Ridge Rd.)
West Seneca 14224

837-6213

712-2000

• Diagnostic audiometric evaluations (pediatric and adult)
• Digital &amp; programmable hearing aid fittings on 60-day trial basis • Tinnitus evaluation and therapy
• Vestibular evaluation for patients with dizziness/vertigo • Vestibular therapy • State of the art facilities

"The Ear is the Road
to the Heart" rvoJraireJ

Daniel Schneider, AuD

Jennifer Schneider, MA

Spring

Jerri Kaplan Joyce, MA

2002

lulfal1 Physician

35

�DEVELOPMENT

N

E

w s

Scholarships for Our Students
By Li nd a J . Cor d e r , PhD, CFRE

OR YEARS, THERE'S BEEN DISCUSSION about
the importance of scholarships- "We're losing some of
our best 'acceptances' due to higher scholarships elsewhere ... ";or, "If we had even one full scholarship, we
might be more competitive ... "
Recently, I decided to look into tuition, average student debt and scholarship assistance at UB. What I found
begs for additional research and analysis, including correlation of tuition with the number of paid full-time
faculty, when medical class size changed and when the
school added basic science programs.
In the interim, I found that UB's tuition has always
been relatively low. Initially, this was due to
the short course of study ( 15 weeks) by people
who were already, in effect, apprentices to
volunteer faculty members who organized the
first curriculum. The Class of 1847 paid $80.
This included their graduation fee.
This situation scarcely changed for 70
years. Although the course of study lengthened, the cost per year remained stable. In
1916, tuition had risen to only $125 a year. In
1928, a mere 12 years
later, medical education had in1:-\CREASL 'G
creased fourfold to $500 annually.
ENDOWMENTS FOR
Another period of stability lasted
SCHOLARSHIPS WILL
through WWII. Then, from 1948
CO, 'TINUE TO BE A
to 1955, costs rose from $600 a
\IA)OR FOCUS FOR
year to $850. During the late 1950s,
THF RE,\!AINDER OF
tuition decreased and fees increasTHE CA\!PAIG::-.. FOR
ed, with the net cost steady. In
UB AND BEYO:\'D.
1959, tuition climbed to $1080,
but fees declined.
Five years later, in 1964, two years after UB's merger
with the State University, tuition dropped slightly to
$800 for New York residents, remaining at $1,000 for all
others, plus a UB fee of $81. This remained constant
through the 1970s, increasing somewhat towards the
end of the decade. By 1982, residents paid $4,300 a year,
when the national average for public medical schools

36

luffalo Physician

Spring

2002

was only $2,1 00! By the early
1990s, tuition was $5,600 for
New Yorkers, nearly $9,000
for others, with fees still at about $300 a year.
We seem to be in another growth mode. Last year
was slightly under $12,000. This year we're at $12,840
in-state and $22,940 out-of-state. There is a projected
annual increase of $2,000 for the next three years.
The above figures might dispel a few myths. Tuition
was incredibly low while UB was private. The clinical
faculty, high in experience, volunteered their time to
teach, which kept costs to students artificially low. The
"drop" in tuition and fees when the school
merged with SUNY was minor. The largest
increases have taken place recently. UB is
still a relative bargain, but the fact is that
medical and biomedical education and research now cost significantly more than they
did for the majority of our graduates.
Our students are graduating with an average debt in excess of$80,000. With current
scholarship endowments, we were able to
award only about $288,000 this academic
year m scholarships. The school's Alumni Scholars
Endowment got a big boost this year with a generous
bequest from AI Dobrak, MD, Class of '39. His gift, in
excess of $200,000, increased this endowment by 53
percent, bringing it to about $580,000. Last year,
Janet Sung, MD, a Western New York radiologist, and
her husband, John, established a scholarship fund
with a million-dollar gift. Several alumni have set up
smaller named scholarship endowments. Every one of
these gifts helps, but the fact is we have a long way to
go. Increasing endowments for scholarships will continue to be a major focus for the remainder of the
Campaign for UB and beyond.

Linda (Lyn) Corder, PhD, is associate dean for alumni
affairs and development. She can be contacted at
I -877-826-3246, or via e-mail at ljcorder@buffalo.edu.

�Lifetime Members
When cumulative contributions reach $50,000 or an irrevocable deferred gift
is completed for $100,000 or more, a couple or individual is granted lifetime
membership in the fames Platt White Society. Combinations of outright and
deferred gifts in appropriate proportions may also be the basis of lifetime
membership. Names of Founders' Circle members are repeated in an annual
category in any year that they make a new gift to the school.

UB' s Founders-primarily physicians and attorneysenvisioned a school to train students for service to the
community. The Society's Founders help to actualize
that vision by providing a generous base of support
for programs and activities that enrich the academic
environment and enhance medical training.

Mrs. Catherine Fix

Martinsburg, WV
Dr. Thomas F. Frawley '44

Chesterfield, MO
Mrs. Christine Gretschel
Genner

Potomoac, MD
Dr. Lawrence Golden '46 &amp;
Mrs. Nancy Golden '48

Mrs. Joan W. Alford

Mrs. Annette Cravens

Buffalo, NY

Buffalo, NY

Mrs. June M. Alker

Mr. Donald l. Davis &amp;
Mrs. Esther P. Davis

Williamsville, NY
Charles D. Bauer, MD '46 &amp;
Mrs. Mary A. Bauer

Williamsville, NY
Dr. Ralph T. Behling '43

Williamsville, NY
Dr. S. Max Doubrava Jr. &amp;
Mrs. Joan Doubrava

Las Vegas, NV

Eggertsville, NY
Dr. Pasquale A. Greco '41 &amp;
Mrs. Lois J. Greco

Buffalo, NY
Dr. Glen E. Gresham &amp;
Mrs. Phyllis K. Gresham '8S

Williamsville, NY
Dr. Thomas Jr. '60 &amp; Mrs.
Barbara l. Guttuso

San Mateo, CA

Mrs. Marjorie B. Eckhert

Dr. Willard H. Boardman '44
&amp; Mrs. Jean E. Boardman '48

Buffalo, NY

East Amherst, NY

Ms. Rose M. Ellerbrock

Dr. Eugene J. Hanavan Jr. '41

Winter Park, FL

Williamsville, NY

Buffalo, NY

Dr. William M. Chardack

Dr. George M. Ellis Jr. '4S &amp;
Mrs. Kelly Ellis

Mrs. Morris Lamer

Gulfstream, FL

Connersville, IN

New York, NY

Dr. Joseph A. Chazan '60 &amp;
Mrs. Helen Chazan

Mrs. Grant T. Fisher

Dr. Eugene R. Minden &amp; Mrs.
June A. Mindell

Providence, RI

Palm Beach, FL

Buffalo, NY

Dr. Phil Morey '62 &amp; Mrs.
Colleen Morey

Dr. Philip B. Wels '41 &amp; Mrs.
Elayne G. Wels

Williamsville, NY

Williamsville, NY

Dr. Richard J. Nagel '53 &amp;
Mrs. Florence T. Nagel

Dr. John &amp; Mrs. Deanna
Wright

Orchard Park, NY

Williamsville, NY

Dr. Richard B. Narins '63 &amp;
Mrs. Ellen B. Narins

East Aurora, NY
Dr. Albert C. Rekate '40 &amp;
Mrs. linda H. Rekate '71

Williamsville, NY
Dr. Elizabeth P. Olmsted
Ross '39

Buffalo, NY
Mrs. Mary Cecina Riforgiato

Buffalo, NY
Dr. Robert J. Smolinski '83
&amp; Dr. Claudia D. Fosket '85

Orchard Park, NY
Dr. Albert Somit

Carlsbad, CA
Dr. Janet H. Sung &amp;
Mr. John J. Sung

Clarence, NY

Spri11g

2002

Annual Memberships
All annual donors of
$1,000 or more are
granted membership in
the]ames Platt White Society. Annual membership in the appropriate
circle within the society
are granted for one year,
beginn ing January 1, for
the gifts received the
prior calendar year.
The roster of the
fames Platt White Society
"Class of 2001" follows.

lullalo Phy sic ian

37

�DEVELOPMENT

I

jAMES PLArr\VHITE. cosT.

Dean's Circle
The dean is the school's
leader. Every leader depends on a small circle
of associates who help
bring the organization's
vision into reality. Individuals or couples qualify as members in the
Dean's Circle with generous gifts of $25,000 or
more during the calendar year.

Professors' Circle
A strong faculty is central to a great university.
Likewise, central to the
future of our school is
the dedication of a cadre
of supporters whose annual gifts range from
$5,000 to $9,999.
Charles D. Bauer, MD '46 &amp;
Mrs. Mary A. Bauer

Williamsville, NY
Dr. Melvin B. Oyster '52

Niagara Falls, NY
Mrs. Lidia Hreshchyshyn

Williamsville, NY
Mr. Donald l. Davis &amp; Mrs.
Esther P. Davis

Williamsville, NY
Dr. Max Doubrava Jr. '59 &amp;
Mrs. Joan Doubrava

Las Vegas, NV
Dr. Janet Sung and Mr. John
Sung

Clarence, NY

Dr. Gordon R. lang '62

Chicago, IL
Dr. John C. Newman

Lewiston, NY
Mr. James I. Stovroff

Buffalo, NY
Dr. Charles S. Tirone '63 &amp;
Mrs. Anne R. Tirone '94

Williamsville, NY

Chairs' Circle

Fellows' Circle

Just as a department
chair leads a program,
donors of leadership
gifts In the range of
$10,000 to $24,999 are
given special recognition.

Fellows within the school
are recognized for added
depth they bring to postgraduate study. Fellows
are honored for gifts that
total $2,500 to $4,999.

Dr. and Mrs. Ernest Beutner

Dr. Willard H. Boardman'44
&amp; Mrs. Jean Boardman '48

N

E

w

Dr. Douglas Sinensky

Dr. Jay Belsky' 51

Dr. Roman Cham

Williamsville, NY

San Pedro, CA

La Mesa, CA

Dr. Robert J. Smolinski '83 &amp;
Dr. Claudia D. Fosket '85

Dr. Richard A. Berkson '72 &amp;
Mrs. Andrea Berkson

Draper, VA

Orchard Park, NY

Rancho Palos Verdes, CA

Dr. Irving Sterman '64 &amp;
Mrs. Gail K. Sterman

Mr. Sheldon M. Berlow

Dr. Isidore S. Edelman

New York, NY
Dr. lawrence Golden '46 &amp;
Mrs. Nancy Golden '48

Eggertsville, NY
Philip D. Morey M.D. '62 &amp;
Mrs. Colleen Morey

Williamsville, NY
Dr. John R. Wright &amp;
Mrs. Deanna P. Wright

Williamsville, NY

Winter Park, FL
Dr. Melvin M. Brothman '58

Snyder, NY

Buffalo, NY

Williamsville, NY
Dr. Yong Baek Chi

Dr. Martin C. Terplan '55

San Francisco, CA

Buffalo, NY
Dr. Theodore S. Bistany '60

Scholars' Circle
One strength of an outstanding institution is
the caliber of those who
study there. Scholars
within the fames Platt
White Society have made
gifts to the school totaling $1000 to $2,499 during the past year. Those
marked with an asterisk
(*) are young scholars,
graduates of the last decade, who qualify with
gifts of $500 to $999.
Mrs. Joan W. Alford

Buffalo, NY
Dr. Kenneth Z. Altshuler '52
&amp; Mrs. Ruth Altshuler

I uI I

a I o n ys i c i a n

West Seneca, NY

Dr. lawrence B. Bone '73

Dr. Charles Kwok-Chi Chow &amp;
Mrs. Patricia Chow

Orchard Park, NY

Hong Kong

Dr. Jerald Bovino '71

Dr. George H. Christ '56

Aspen, CO

Largo, FL

Dr. Suzanne F. Bradley '81

Dr. Eugene Cisek

Whitmore Lake, MI

Buffalo, NY

Dr. Martin Brecher '72 &amp;
Geri Brecher

Dr. Mark Comaratta '85

Amherst, NY

East Amherst, NY

Dr. Harold Brody '61

Dr. Bernice S. ComfortTyran '58

Getzville, NY

Los Altos, CA

Dr. James B. Bronk '81 &amp;
Mrs. Suzanne Bronk

Buffalo, NY

Napa, CA
Dr. August A. Bruno Sr. '51

Buffalo, NY

Dr. linda J. Corder

Dr. J. Steven Cramer

East Amherst, NY
Dr. Julia Cullen '49

Buffalo, NY

La jolla, CA

Dr. Daniel E. Curtin '47 &amp;
Mrs. Elaine Curtin

Dr. Stanley Bukowski '81

Orchard Park, NY

Buffalo, NY

Dr. Stanley J. Cyran Jr. '46

Prospect, KY

Dr. William S. Andaloro '45

Chapel Hill, NC

Dr. David R. Dantzker '67 &amp;
Mrs. Sherrye Dantzker

Dr. James P. Burdick '75

Roslyn, NY

Caledonia, NY
Dr. Mark Anders
Dr. Douglas Armstrong

Buffalo, NY
Dr. J. Bradley Aust Jr. '49

San Antonio, TX

Lemoyne, PA

Hamburg, NY

Dr. Charoen &amp; Dr.
Charlearmsee Chotigavanich

Dr. Jared C. Barlow Sr. '66 &amp;
Mrs. Barbara Barlow

Thailand

Grand fsland, NY

East Amherst, NY
Dr. William M. Burleigh '67

Rar1cho Mirage, CA
Mrs. John Buyers

Little Silver, NY
Dr. Roger S. Dayer '60 &amp;
Dr. Roberta A. Dayer '72

Williamsville, NY

Buffalo, NY
Dr. Gerard J. Diesfeld '60

Hamburg, NY
Dr. David T. Carboy '63 &amp;
Mrs. Jacqueline G. Carboy

Lincroft, N]

Dr. Nancy H. Nielsen '76

Mrs. Agnes T. Baron

Orchard Park, NY

Snyder, NY

Eden, NY

Dr. Thomas P. O'Connor '67

Dr. Michael B. Baron '71

Dr. Nicholas C. Carosella '54

&amp; Mrs. Sandra S. O'Connor

Blountville, TN

Appleton, NY

Dr. Paul D. Barry '71

Dr. leonard S. Danzig '51

Dr. Evan Calkins &amp;
Dr. Virginia Calkins

Dr. Joseph G. Cardamone '65
&amp; Mrs. Susan G. Cardamone

2002

Dr. Prem Chopra

Dr. Timothy Bukowski '87 &amp;
Dr. Naomi J. Kagetsu '86

Dr. George Bancroft '81 &amp;
Mrs. Susan K. Bancroft '79

Spring

Lockport, NY

Dallas, TX

Arlington, VA

38

Buffalo, NY

Dr. Helene E. BuergerPeck'56

Dr. Jennifer l. Cadiz '87

East Amherst, NY

Dr. Norman Chassin '45 &amp;
Mrs. Charlotte S. Chassin

Dr. Michael E. Bernardino &amp;
Mrs. Joan Bernardino

jacksonville, FL

Buffalo, NY

Eggertville, NY

Dr. Yung C. Chan '73

Arcade, NY
Mr. James B. Docherty

Orchard Park, NY
Ronald I. Dozoretz M.D. '62

Falls Church, VA
Dr. Robert Einhorn '72

North Brunswick, Nj
Dr. Domonic F. Falsetti '58 &amp;
Mrs. Margaret Falsetti

Lewiston, NY

�Dr. Leon E. Farhi &amp;
Mrs. Haya Farhi

Eggertsville, NY

Dr. Carl V. Granger

Buffalo, NY

Dr. Bernard J. Feldman '66

Dr. Glen E. Gresham &amp; Mrs.
Phyllis K. Gresham '85

Palos Park, IL

Williamsville, NY

Mr. Kevin Feor '80 &amp;
Mrs. Elizabeth A. Feor '78

Dr. Robert T. Guelcher '60 &amp;
Mrs. Elizabeth Guelcher

Webster, NY

Erie, PA

Dr. James R. Kanski '60 &amp;
Dr. Genevieve W. Kanski '84

Dr. Gerald L. Logue &amp;
Mrs. Joelle Logue

Eggertsville, NY

Williamsville, NY

Latrobe, PA

Dr. Steven R. Kassman '87 &amp;
Mrs. Jeannine Kassman

Dr. Thomas A. Lombardo Jr.
'73 &amp; Mrs. Donna M.
Lombardo

Dr. Margaret W. Paroski '80

Glendale, AZ
Dr. Kenneth K. Kim '65 &amp;
Mrs. Susan W. Kim

Clinton, NY

East Aurora, NY
Dr. Frank A. Luzi '88 &amp;
Dr. Lori Luzi '88

Bethlehem, PA

Dr. Robert Joseph Hall '48 &amp;
Mrs. Dorothy N. Hall

Dr. Francis J. Klocke '60

Dr. Helen Marie Findlay '78
Dr. Albert Schlisserman '77

Houston, TX

Chicago, JL

Dr. Christopher Hamill '89

Dr. Robert A. Klocke '62 &amp;
Mrs. Barbara Klocke

Dr. Brian McGrath

*Dr. Amy E. Ferry '94

Clarence, NY
Dr. John M. Marzo '86

Buffalo, NY

Eggertsville, NY

Buffalo, NY
Dr. Donald Hauler '57 and
Mrs. Barbara Hauler

Williamsville, NY

Buffalo, NY

Dr. Ludwig R. Koukal '51

Dr. Susan V. McLeer

Pensacola, FL

Tucson, AZ

Buffalo, NY

Dr. Mark Heerdt '51 &amp; Mrs.
Lois Heerdt

Dr. Joseph M. Kowalski '93

Dr. Harry L. Metcalf '60 &amp;
Dr. Kaaren Metcalf '78

Dr. Susan Fischbeck '82 &amp;
Dr. Patrick T. Hurley '82

East Concord, NY
Dr. Jack Fisher '62

La jolla, CA
Dr. John Fisher

Buffalo, NY
Dr. Thomas D. Flanagan '65
&amp; Mrs. Grace Flanagan '70

Williamsville, NY
Dr. William A. Fleming '64 &amp;
Dr. Beth D. Fleming '67

Greer, SC
Dr. Reid R. Heffner Jr. &amp; Mrs.
Elenora M. Heffner

Buffalo, NY

Amherst, NY
Dr. Daniel Kozera '59

Lackawanna, NY
Dr. Kenneth Krackow

Williamsville, NY

Dr. Fredric M. Hirsh '73 &amp;
Mrs. Donna A. Hirsh

Dr. Jacob S. Kriteman '67

Williamsville, NY

Danvers, MA

Dr. John M. Hodson '56

Dr. Harold Krueger '51

Williamsville, NY

Rockford, IL

Buffalo, NY

Mr. Paul F. Hohenschuh &amp;
Dr. Marjorie E. Winkler

Dr. Ivan W. Kuhl '45

Dr. Neal W. Fuhr '52

Burlingame, CA

Dr. Marie Leyden Kunz '58 &amp;
Dr. Joseph L. Kunz '56

Williamsville, NY

Ms. Peggy Hong
Dr. Robert Galpin

Milwaukee, WI

Buffalo, NY

Wimberley, TX

Lockport, NY
Dr. Andre D. Lascari '60

Dr. Penny A. Gardner '69

Dr. Waun Ki Hong &amp; Mrs.
Mihwa Hong

Los Altos, CA

Houston, TX

Drs. Laura &amp; Michael Garrick

Dr. Bradley Hull '41

Brooklyn, NY

Getsville, NY

Rocky River, OH

Dr. Mark J. Lema '76 &amp;
Mrs. Suzanne Lema

Dr. Ronald F. Garvey '53

Dr. Hilton R. Jacobson '45

Tyler, TX

Lakewood, NY

Mr. Warren Gelman '70

Robert M. Jaeger, M.D. '47

Buffalo, NY

Allentown, PA

Dr. George A. Gentner '41

Dr. Charles Alexander Joy '46

Poestenkill, NY
Dr. Sanford E. Left '68

East Amherst, NY
Dr. Dolores C. Leonard '87 &amp;
Mr. Martin Leonard

East Amherst, NY
Dr. Eugene Leslie '51 &amp; Mrs.
Faith Leslie

Buffalo, NY
Dr. Robert J. Patterson '50 &amp;
Mrs. Patricia M. Patterson

Snyder, NY
Dr. Norman L. Paul '48

Lexington, MA

Dr. Marc S. Fineberg

Williamsville, NY

Dr. John S. Parker '57 &amp;
Mrs. Dorris M. Parker

Dr. Joel H. Paull '71 &amp;Mrs.
Linda Paull

Eggertsville, NY
Dr. John H. Peterson '55

East Aurora, NY
Dr. Harry E. Petzing '46

Hamburg, NY

Williamsville, NY

Dr. Daniel Phillips '51 &amp;
Mrs. Mary Ann Phillips

Dr. Merrill L. Miller '71

Reno, NV

Hamilton, NY

Dr. James F. Phillips '47 &amp;
Mrs. Marcella Phillips

Ms. Sounghae Min

Korea

Buffalo, NY

Dr. David P. Mindell &amp;
Mrs. Margaret H. Mindell

Dr. Matthew Phillips '91

Ann Arbor, M I

Buffalo, NY
Dr. Anthony V. Postoloff '39

Dr. Maynard H. Mires Jr. '46

Georgetown, DE

Williamsville, NY
Dr. Richard A. Rahner '58

Dr. John A. Moscato '68 &amp;
Dr. Beth A. Moscato '96

Orchard Park, NY

Erie, PA
Dr. John Y. Ranchoff '52

Fairview Park, OH

Dr. John D. Mountain '33

Manhasset, NY
Dr. Arthur W. Mruczek Sr.
'73

Medina, NY

Dr. Bert W. Rappole '66 &amp;
Mrs. Mary Helen Rappole

jamestown, NY
Dr. Frederic D. Regan '45

Boca Rator1, FL

Dr. Richard L. Munk '71

Sylvania, OH

Dr. Robert E. Reisman '56 &amp;
Mrs. Rena Reisman

Dr. Masao Nakandakari '55

Williamsville, NY

Honolulu, HI

Dr. Bernhard Rohrbacher '83

Dr. Richard Narins '63 &amp;
Mrs. Ellen Narins

Getzville, NY
Dr. Richard Romanowski '58

Phoenix, AZ

Fairview, PA

Dr. Allen L. Goldfarb '51

Buffalo, NY

Dr. Herbert E. Joyce '45 &amp;
Mrs. Ruth Marie Joyce

Dr. Elizabeth P. Olmsted
Ross '39

Dr. Michael Gold hamer '64

Dr. Harold J. Levy '46 &amp; Mrs.
Arlyne Levy

Depew, NY

Lockport, NY

Dr. Tomoe Nishimaki

Buffalo, NY

San Diego, CA

Mr. Arthur H. Judelsohn

Amherst, NY

japan

Ms. Barbara Mcalpine
Gong'90

Buffalo, NY

Dr. Seymour J. Liberman '61

Dr. Ralph M. Obler '52 &amp;
Mrs. June M. Obler '49

Williamsville, NY
Dr. Myron Gordon '48

Dr. Jeffrey Kahler '66

Chapel Hill, NC

Albany, NY

Dr. Wendy A. Kaiser '85 &amp;
Dr. Roger E. Kaiser Jr. '79

Dr. Walter Grand

Clarwce, NY

Williamsville, NY

Williamsville, NY

Slwker Heights, OH
Dr. Hing·Har Lo '74

Blacksburg, VA

Dr. Alice Challen LoGrasso '37
Alameda, CA

East Aurora, NY

Buffalo, NY

Dr. John Naughton

Dr. Jeffrey S. Ross '70

Los Angeles, CA

Lebanon Springs, NY
Dr. Albert G. Rowe '46

Tonawanda, NY

Dr. Rudolph Oehm '66

Walnut Creek, CA

Dr. Joseph F. Ruh '53

Orchard Park, NY

Dr. Kathleen O'Leary '88 &amp;
Mr. Michael J. Collins '90

Buffalo, NY

Spring

2002

B u If a I o P h y s i c i a n

39

�~

-~

--

---~

-

---

DEVELOPMENT

I

jA\f ES PLATT W HITE

CO"\T.

Dr. Edwin A. Salsitz ' 72

New York, NY
Dr. Iqbal A. Samad &amp;
Mrs. Vicar Samad

Williamsville, NY
Mrs. Elizabeth Ann Schaefer

Snyder, NY
Dr. David S. Schreiber '69

Westwood, MA
Dr. Fred S. Schwarz ' 46

Buffalo, NY
Dr. Molly R. Seidenberg '53

Rochester, NY
Dr. Elizabeth G. Serrage '64

Cape Elizabeth, ME
Mr. Eugene M. Setel

Buffalo, NY
Dr. Timothy S. Sievenpiper
' 68 &amp; Mrs. Karen S.
Sievenpiper

40

Dr. Daniel J. Tutas

Washington Grove, MD

Dr. Gregory E. Young '77 &amp;
Mrs. Diane Young

Dr. John J. Squadrito ' 39

Dr. Salvador M. Udagawa &amp;
Mrs. Aurora Udagawa

Dr. Wende W. Young '61

Lake View, NY

Cmw11daigua, NY

Dr. Alvin Volkman ' 51

*Ms. Sandra Yu ' 95

Greenville, NC

Malden, MA

Dr. Coolidge S. Wakai '53

Dr. Franklin Zeplowitz ' 58 &amp;
Mrs. Piera Zeplowitz

Albany, NY
Dr. Philip M. Stegemann '82

Orchard Park, NY
Dr. Morton A. Stenchever '56

Mercer Island, WA
Dr. William C. Sternfeld '71

Sylvania, OH
Mr. Franz T. Stone

Clarence, NY
Mrs. Gloria Stulberg

Buffalo, NY
Dr. Michael A. Sullivan '53

Williamsville, NY
Dr. Joseph Tannenhaus '45

Homosassa, FL
Dr. Michael Taxier '75

Columbus, OH
Dr. Wayne C. Templer '45

Dr. Howard C. Smith '53

Mr. Fritz Terplan

Huron, OH

San Francisco, CA

Dr. James A. Smith ' 74

Dr. James C. Tibbetts '64

Orchard Park, NY

Sturgeon Bay, W I

Dr. Robert G. Smith '49

Dr. Bradley T. Truax '74

Savannah, GA

Lewiston, NY

internationally renowned
designer of bridges who in
1923 bequeathed nearly
$390,000 to UB. Through
the years, many generous
individuals have been inspired by the same conviction and have elected to
build on Hayes' foundation of support. Through
their commitment to the
university, and through
their investment in University at Buffalo, benefactors have taken part in
shaping the future of UB
and securing its legacy into
the next century.

I u II a I a

n ysic ian

S

Encinitas, CA

Corning, NY

This society is named after
General Edmund Hayes, an

W

Dr. Albert Somit

East Aurora, NY

The Edmund Hayes Society

E

Several of the Medical
School's friends and
alumni have joined the
Edmund Hayes Society,
demonstrating their support of our school by
including the UB School
of Medicine and Biomedical Sciences in their
estate plan.
If you are interested
in becoming a member
of the Hayes Society, you
can contact our planned
giving department at
(7 16) 645-3312.
Dr. Frances R. Abel
Mrs. June M. Alker
Dr. Charles A. Bauda
Dr. John T. Cangelosi

Spri11 g

200 2

Honolulu, HI
Dr. Richard D. Wasson '58 &amp;
Mrs. Janet Wasson

Holland, NY

Buffalo, NY

Holiday, FL

Dr. David C. Ziegler '64 &amp;
Mrs. Susan D. Ziegler

Dr. Arnold Wax '76

Walnut Creek, CA

Henderson, NV
Dr. Charlotte C. Weiss '52 &amp;
Dr. Hyman Weiss

Highland Park, N]
Dr. Paul H. Wierzbieniec '74

&amp; Ms. Ellen Wierzbieniec
Buffalo, NY
Dr. Gary J. Wilcox '73

Carlsbad, CA

Special Members
A few individuals and
couples were gra nted
multi-year memberships based on generous
gifts made between 1989
and 1993.

Dr. Myron E. Williams Jr. ' 46

Batavia, NY
Dr. Richard G. Williams '80

Clearfield, PA
Mr. Ralph C. Wilson Jr.

Orchard Park, NY

Dr. Robert Bernot '60 &amp;
Mrs. Carol Bernot

North Hills, NY
Dr. Marvin Z. Kurian '64 &amp;
Mrs. Eleanor Kurian

Williamsville, NY

Dr. Stanley B. Clark

Dr. Richard F. Kaine

Mrs. Edith Corcelius

Dr. J. Walter Knapp

Dr. Linda J. Corder

Dr. Harold J. levy

Dr. Julia Cullen

Dr. Sanford H. levy

Dr. Thomas G. Cummiskey

Dr. Milford C. Maloney &amp;
Mrs. Dione E. Maloney

Mr. Edward l. Curvish Jr.
Dr. leonard S. Danzig
Dr. Melvin Oyster
Ms. Rose M. Ellerbrock
Dr. George M. Ellis, Jr.
Mrs. Grant T. Fisher
Dr. Jack C. Fisher
Dr. lance Fogan
Dr. Ronald F. Garvey
Dr. Pasquale A. Greco
Dr. Glen E. Gresham
Dr. Eugene J. Hanavan Jr.
Dr. David M. Holden
Dr. Hilliard Jason &amp; Dr. Jane
Westberg

Dr. Kart l. Manders
Dr. Benjamin E. Obletz
Dr. Richard A. Rahner
Dr. Albert C. Rekate
Dr. Myron G. Rosenbaum
Dr. Elizabeth P. Olmsted
Ross
Dr. Daniel S. P. Schubert
Dr. Albert Somit
Dr. Eugene M. Teich
Dr. Pierce Weinstein
Dr. John R. Wright &amp;
Mrs. Deanna Wright
Dr. Wende W. Young

�Dear Fellow Alumni,
nother Spring Clinical Day and Reunion Weekend has comeai1d gone, the success
of which will be reported on in detail in the summer issue of Buffalo Physician.
As I close out my two-year term as president of the Medical Alumni Association (MAA ), l feel
I would be remiss not to thank some of the people who have made my job very easy, including

Nancy Druar, our longtime secretary, and Mary Glenn, director of constituency relations and the
school's liaison with our association, both of whom have greatly assisted me.
I also want to thank all the current and past MAA board members and my fellow

officers-Colleen Matti more, MD '91, and Stephen Pollack, MD '82-for the help they
have lent toward making the different activities we had throughout the year very successful. I appreciate everything you have done for the association and for the school.
In my final message as president, l would like to remind you of the three major
awards the MAA bestows on our fellow alumni throughout the year. I think that these
awards are very special and that more of our alumni need to know the criteria for
nominating individuals to receive them.
The Distinguished Alumn us Award, our most prestigious award, is presented each September
at the dinner for past presidents. The qualifications for the award are an alumnus who has
distinguished himself or herself nationally or internationally among peers and who has made an
outstanding contribution to medicine or to the arts and humanities.
The Med ical Alumn i Ac hievement Awa rds and the Robert S. Berkso n Memorial Award are the
other two awards, which are presented during Spring Clinical Day in April each year.
The achievement awards are presented to alumni who have shown conspicuous and outstanding achievement in one of the following areas of medical endeavors: teaching, research, innovation,
practice, service, and medical administration. Traditionally, these awards are given to alumni
celebrating their reunions that year so that their classmates and friends can join with them in
celebrating their success.
The RobertS. Berkson Award has been presented since 1988 in memory of Dr. Berkson, a wellknown internist in the Western New York community. It honors a physician who has performed his
or her teaching responsibilities in an outstanding manner during five or more years on the volunteer
teaching faculty and who combines scholarship and compassion in a way that elevates medicine, in
its best sense, from a science to an art.
Because I am sure there are many deserving alumni who have not yet been recognized by our
association, I encourage you to write to the MAA office to nominate a peer for one of these awards.
If you prefer to send your nominations via e-mail, they can be forwarded to Mary Glenn at
glenn@acsu.buffalo.edu.
In closing, I would also just like to put one more plug in for all eligible candidates-medical
school alumni, faculty, PhD graduates and emeritus professors-to join our association and, if
you are able, to become a lifetime member.
Again, thank you for the honor of allowing me to serve as your alumni association president.

4d14eft4·?
BooL,~:~
JoHN J.

' 76

President, Medical Alumni Association

S prin g 20 0 2

Buffalo Physician

4 1

�~~- -------

C

L

A

SNOTES

1940s
Raymond Bondi, MD '44,

writes: "Enjoying
salubrious and warm
South Florida. I even
exercise daily, with a
knife and fork."

1950s
Joseph F. Ruh, MD '53,

writes: "I retired from the
office in 1996, but am
working at the hospital
one day a week doing GI
endoscopy." E-mail address is joe@ruh.net.

Over the years, Bell
has been nationally recognized for his extensive
work in promoting
women's health issues,
particularly familycentered OB care. In
1980, he pioneered the
certified
nurse
mid-

University of California,
Irvine.
Michael I. Weintraub, MD
'66, FACP, FAAN, writes: "I

am in full-time private
practice of neurology and
pain medicine. Currently, I am performing
clinical research with dia-

Medical Center in Anaheim, CA. At that time,

betic peripheral neuropathy and carpal tunnel
syndrome with alternative modes of therapy;
i.e., magnetic therapy
and laser therapy. I have
over 190 publications,

James Youker, MD '54,

it was the first such pro-

and recently I edited a

writes: ''I'm still working

gram within the Kaiser

book, titled Alternative

and chair of radiology at
the Medical College of
Wisconsin. In March
2002, I finish my two-

system and one of the
first in the nation.

and Complementary
Treatment in Neurologic
Illness (Churchill
Livingstone, 2002). Presently, I am clinical professor of neurology and
medicine at New York
Medical College and ad-

wifery
program
at Kaiser

Jacob (Jack) Lemann Jr.,
MD '54, New Orleans, LA.

E-mail address is
dr.jack@lemann.net.

year term as president of
the American Board of
Medical Specialties."
E-mail address is:
jyouker@mcw.edu.

1960s
Kenneth Bell, MD '61. After

33 years as a Kaiser
Permanente obstetrician
and gynecologist, including the last 14 years as
area medical director for
the organization in Orange County, CA, Bell
retired from the Southern California Permanente Medical Group on
December 31, 2001.

42

assnotes

luff al a Ph ysici an

Pemlallel1te

In 1997, he was honored with the prestigious
Mentor in Medicine
Award from the March of
Dimes for his commitment to and leadership in
the community and the
healthcare industry.
While Bell is retiring
from Kaiser Permanente,
he is not giving up his
work as a medical administrator. On January
2, 2002, he stepped into
his new role as CalOptima's chief medical
officer (Cal-Optima
is Orange County's
Medi-Cal managed care
program).
He also serves as
clinical professor at the

Spri11g

2002

junct clinical professor of
neurology at Mount Sinai
School of Medicine in
ew York City."

from 1987 to 1990."
E-mail address is
andyandcarole@netzero.net.

E-mail address is:
miwneuro@pol.net.

Barry Schultz, MD '&amp;B.

John R. Anderson, MD '67,

Wyomissing, PA, writes:
"After a year at sea, I
spent the next year doing

Depew, NY, writes:
"In 1998, I retired

nothing but vasectomies
16/day, 5/day week. Then

from Brothers of Mercy
Hospital, where I was

I went into urology at the
University of Connecticut with classmate Bruce
Stoesser. I am now chief

medical director. From
1999 to 2001, I taught
anatomy and physiology
and medical terminology
at Bryant &amp; Stratton.
Currently, I work as a
program physician two
days a week at UB's
Research Institute on
Addictions. I had two
teaching degrees before
earning my medical
degree, and would love
to teach in the medical
school again, as I did

of urology at the Reading
Hospital and Medical
Center in my hometown.
I am past president of the
Urological Association of
Pennsylvania. I may slow
down a bit after I get
new knees."
John Fisk, MD '69, profes-

sor of surgery at Southern Illinois University
School of Medicine, was

�HUNT
Since 1911

elected in january 2002
to a two-year term as
chair of the board for the
U.S. members of the International Society for
Prosthetics and Orthotics.

Hunt Relocation Center

1970s
Donald H. Marcus, MD '71.

Northridge, CA, writes:
"! have just been reelected to the board of

directors of the Southern
California Permanente
Medical Group for my
seventh three-year term.
My daughter Elizabeth is
in her second year at the
University of Southern
California School of
Medicine."
Diane L. Matuszak, MD '74,

MPH, was appointed director of Community
Health Administration in
the Maryland Department of Health and Mental Hygiene, effective
December 26, 2001. This
administration oversees
all local health departments and statewide programs for Epidemiology
and Disease Control (including bioterrorism),
Food Protection and
Consumer Health Services, Environmental
Health and Health Planning. E-mail address is
dmatuszak@home.com.
Greg Antoine, MD '76,

writes: "! am the new
chairman of plastic surgery at Boston University
School of Medicine. I am
board certified in plastic

surgery and otolaryngology. I specialize in congenital and posttraumatic
facial reconstruction. I
retired as a colonel from
the Army and was formerly on the faculty at
Case Western Reserve
University School of
Medicine. My son
Elliott's high school football team won the Ohio
State Division I championship. My daughter,
Tai, graduated from
Dartmouth, and my son
Greg got a master's degree from the University
of Miami, both in june. I
am sad to hear that UB
lost its otolaryngology
residency program.
Jane (King) Dorval. MD '76,

was recently elected chair
of the Rehabilitation Accreditation Commission's (CARF) board of
trustees for the 2002
term. CARF is a private,
nonprofit organization
that promotes quality rehabilitation services by
establishing standards of
quality for national and
international organizations to use as guidelines
in developing and offering their programs or
services to consumers.
CARF standards are

developed with input
from consumers, rehabilitation professionals,
state and national organizations and those funding
the process. There are
more than 26,000 medical,
behavioral, employment/
community services, adult
day services and assistedliving CARF-accredited
programs in the U.S.,
Canada and Europe.
As a board-certified
physiatrist, Dorval is currently senior vice president of medical affairs
and quality oversight at
Good Shepherd Rehabilitation Hospital in Allentown, PA. She is also a
division chief of rehabilitation medicine at
Lehigh Valley Hospital,
also in Allentown, and a
clinical associate professor on the faculty of
Pennsylvania State University School of Medicine in Hershey, PA.

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Ira Salom, MD '77, has been

appointed to the ew
York State Board of
Medicine, in the Office of
the Professions, State
Education Department,
to serve on license restoration and moral fitness
hearing panels.

Mary Croglio
Corporate Relations

Officer
Hunt Relocation Center
5570 Main Street
Williamsville, NY 14221 -5410
Email: huntrelocation@huntrealestate.com

S p r in g

2002

8 u f fa I o Physician

43

�CLASSNOTES

Fred H. Geisler, MD '78,

publ ished three papers
on the natural evolution
and treatment of spinal
cord injury in the December 200 I issue of the
journal Spine. He works
in the Chicago Institute
of Neurosurgery and
Neuroresearch, specializing in spinal instrumentation. E-mail address is:
fgeis ler@co ncen tric. net.
Leigh Lachman, MD '78,

writes: "I live in New Jersey and practice in Manhattan . I am boarded in
both otolaryngology and

,;._..;.

genera l plastic surgery.
I'm married and have
three children: two girls,
ages 10 and 17, and a
boy, age 13. I truly miss
those days and parties in
medical school. I'd be
happy to hear from my
friends, who can e-mail me
at devilsrul9@aol.com. "
Roger E. Kaiser, Jr, MD '79,

has been appointed
medica l di rector of the
Erie County Medical
Center (ECMC)
Hea lthcare Network. The
network encompasses a
base of off-campus

health centers, an advanced academic medical
center with 500 inpatient
beds and 156 skilled
nursing home beds, and
the Erie County Home, a
638-bed skilled nursing
facility.
Kaiser,
who has
served as
clinical
director
of the Department of Anesthesia!ogy (1989-present) and
as attend ing anesthesio logist ( 1983-present) at
ECMC, will continue to

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44

Buffalo Phys i cian

Spring

2002

practice in these capacities. He also concurrently
serves as medical director at the Western New
York Center for Ambulatory Surgery (2001present) and is associate
professor of clinical anesthesiology (1993present) for the University at Buffalo's School of
Medicine and Biomedical Sciences. Kaiser is a
member of the American
College of Physician Executives, Society of Critical Care Medicine,
American Society of Anesthesiologists, and In-

ternal Anesthesia Research Society.

1980s
Frank W. Sanchez, MD '8D,

writes: "I am in my sixteen th year of practice in
interventional radiology.
l am president of the
medical staff at Memorial Hospital in Jacksonville, FL. I had a great
time at the 20th reunion
in spring 2000."
John Claude Krusz, PhD, MD
'83, Dallas, TX, was

elected vice president of

�~-~~--~

the American Board of
Electroencephalography
and Neurophysiology
(ABE ), which administers board certification
exams in EEG. Krusz
recently cofounded the
ational Deaf People's
Institute, a nonprofit
organization dedicated
to providing clinical services to the deaf and
hard of hearing. E-mail
address is nodynia@
swbell.net.
Joseph Carrese, MD '84,
MPH, Ellicott City, MD,

writes: "I was recently

~-

-----

promoted to associate
professor of medicine at
The johns Hopkins
University School of
Medicine (November
2001), and am a core
faculty member of The
johns Hopkins University Bioethics Institute. "
E-mail address is:
jcarrese@jhmi.edu.

-

physician assistant. We
also expanded our office.

John R. Fudyma, MD '85,

l continue to enjoy the
full spectrum of family

ciate medical director of
the Erie County Medical

care, including obstetrics.
My spare time goes into
maintenance of home,
yard and kids. Rachel
( 16) is hoping to drive
soon. jacob (12) is work-

work. Fudyma is currently associate professor
of clinical medicine in
internal medicine ( 1998-

Benson Zoghlin, MD '84,

ing on preparing for his
bar mitzvah. Mindy, my
wife, is practicing law

Hilton, Y, writes:
"Our family practice
group expanded again

and working on her second-degree belt in lsshin
Ryu Karate." E-mail

last year to five full-time
docs, one part-time (my
semi- retired dad) and a

address is: drben862
@aol.com.

has been appointed asso-

Center Healthcare Net-

present) and associate

ties, including assistant

program director of the
Internal Medicine Residency Program A ( 1996present) through the
University at Buffalo's

program director (19951996), assistant clinical
professor ( 1991-1998),
clinical instructor
( 1989-1991 ) and clinical

School of Medicine and
Biomedical Sciences. He

assistant instructor
(1985- 1989). The ECMC

has also served in other
university faculty capaci-

Healthcare Network
encompasses a base of

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S prin g

2 0 02

Bu f f a I a Phys i cia n

45

�CLASSNOTE

off-campus health centers, an advanced academic medical center
with 500 inpatient beds
and 156 skilled nursing
home beds, and the Erie
County Home, a skilled
nursing facility.
Kathleen O'Leary, MD '88,

has been appointed director of the Operating
Room at Roswell Park
Cancer l nsti tu te
(RPCI ). In her new position, O'Leary coordinates the scheduling,
staffing
and
day-today adm I IllStration
of the

seven operating rooms at
RPCI, in which 3,500
procedures are performed annually.
O'Leary joined the faculty of the Department of
Anesthesiology and Pain
Medicine at RPCI in 1992.
She has served as medical
director of the PostAnesthesia Care Unit
(1993-1995); medical director of the Respiratory
Therapy Department
(1993-1995); director of
resident education in the
Department of Anesthesiology ( 1994--1997); chief
of surgical anesthesia
(I 997); and vice chair of
the Department of Anesthesia (2000.)

Howard Chang, MD '89:

Dawn and Howard are
pleased to announce the
birth of Katherine Mei
Chang on December 17,
2001. She weighed in at 5
pounds, 13 ounces, and
was 17.5 inches long.
Baby Kate is blessed with
lots of beautiful, silky
black hair and has features similar to that of her
sisters, jenny and Marisa,
who are thrilled with their
new baby sister.

town Seattle. Our three
girls keep us very busy and
sleepless ... (in Seattle!) ."
E-mail address is
longomc@aol.com.
IIana Feinerman, MD '93,

writes: "My husband ,
Cary, and I have settled
in Dartmouth, MA. I
have just become a partner in my practice. We
have a son, jeremy, who
is a green belt in tae
kwon do. Our daughter,
Emily, is two, and our

1990s

third baby is on the way. "

Marie Christine Longo, MD

Lisa F. Keicher, MD '93,

'92, writes: "Mike and I are
happily transplanted in the
Pacific Northwest-great
outdoors-and we both
have great jobs in down-

writes: " Last summer my
husband, Steve, and I experienced the greatest
and most rewarding adventure of our lives! We

In Men1orian1

SPRING

46

traveled halfway around
the world to Kazakhs tan,
where we adopted our
beautiful son, Eli Sergei!

He is now a healthy,
thriving one year old
who is the love of our
lives! We continue to live
in Verona, NY, where I
practice general pediatrics, and my hubby,
veterinary medicine. "
E-mail address is
scneth@dreamscape.com.
CONTINUED ON PACE 48

2002

Marvin L. Amdur,
MD'36

Buffalo, NY, from early

tions. He frequently deliv·

two sisters, Adele "Ettie"

childhood. Following gradua-

ered expert testimony on

Brock and Genevieve

ing Long Island University,

Marvin L. Amdur, MD '36,

tion from the then-University

and wrote about toxic expo-

"Shaney" Cohen of

Helfert achieved distinction

emeritus professor of Social

of Buffalo School of Medi-

sure to substances, includ-

Rochester, NY, six grand·

by graduating from the

and Preventive Medicine in

cine, he practiced occupa-

ing lead and asbestos. In

children and two great-

then-University of Buffalo

the University at Buffalo

tiona! medicine and was

the mid-1980s, a lifelong

grandchildren.

Dental School in 1934 and ,

School of Medicine and Bio-

director of the Buffalo

interest in art led Amdur

medical Sciences, died on

Industrial Medical Center

back to UB, where he stud-

sors, from UB's Medical

JanuarY 18, 2000, in San

at 755 Tonawanda Street, a

ied with the artist Harvey

Irving Helfert,
DDS,MD'36

Diego, CA. Amdur, 86, was

private group practice (with

Breverman. In later years he

a pioneer in occupational

Drs. Robert A. Caputi,

also developed his skills on

medicine and an expert on

Harold L. Graff and John N.

the organ and piano. In ad-

toxic exposure in the work·

Strachan) for 50 years be-

dition to his wife, Myra,

place who, in his 70s, re·

fore retiring. Amdur served

Amdur is survived by a

turned to college to earn a

as a consultant to industrY,

daughter, Susan Hayman of

degree in fine arts. A native

federal and state govern-

San Diego, CA; a son, Dr.

of Erie, PA, Amdur lived in

ment and private organiza-

Mark Amdur of Chicago, IL;

la ff al1 Physician

Spring

2002

Hall High School and attend·

by invitation of the profes-

Irving Helfert, DDS, MD '36,
died on December 10, 2001,
at age 90. Born and raised
in Brooklyn, NY, Helfert was
the son of a well-known New
York tailor of fine men's
clothing. After graduating
with honors from Erasmus

School in 1936.
Helfert was chief resident in urology at Columbia
University and assisted in
the advanced development
of the well-known Gomco
Clamp circumcision tool. He
was board certified in urology, a Fellow of the Ameri-

�I

CONTINUED FROM PAGE 46

can College of Surgeons and
a Fellow of the International
College of Surgeons.

grandson Dylan B.

from Niagara Falls High

1930s and later the railway

surgeon from 1956 to 1981,

Swerdlow; sisters Gertrude

School in 1942. He attended

mail service. During World

with offices in the San

Tarnower and Rena Rifkin,

the then-University of Buf-

War II, he served in the

Fernando Valley, CA. He is

and former wife Sylvia

falo for premedical and

Army Corps. Upon discharge

survived by his wife, Helen.

medical school studies,

from the military, Erickson

Dinhofer Helfert.

Helfert moved to Day·
ton, OH, in 1943 and served
as chief of staff and chief of

Amo John Piccoli,
MD'46

surgery at St. Elizabeth and

Amo John Piccoli, MD '46,

Good Samaritan Hospitals.

died February 19, 2000, in

Shortly after World War II,

Fort Myers, FL. He was 77.

at the request of the U.S.

Piccoli, originally from Roch-

Government, he was one of

ester, NY, received his

the first doctors to adminis·

bachelor's degree from

ter penicillin to civilians. If a

Cornell University and his

patient could not afford life·

medical degree from the

saving surgery, Helfert was

then-University of Buffalo.

known to accept homemade

He completed his training

pies in lieu of payment and

and residency at the Roches-

was remembered as a ere·

ter General Hospital and

ative, caring and beloved

served as a major in the U.S.

doctor who found tremen·

Army during World War II.

dous satisfaction in helping

Piccoli practiced internal

people from all walks of life.

medicine at Rochester Gen-

In 1971, he moved to

eral Hospital until retiring in

los Angeles, CA, and joined

1990, when he moved to

the Sherwood Trimble Medi·

Fort Myers.

cal Group with the intention

He was a member of the

of practicing urological

Monroe County Medical So-

medicine with his son, Cap·

ciety, New York State Medi-

tain Bruce Stephen Helfert,

cal Society, New York State

MD, who died in 1972.

Society of Internal Medicine,

While in practice in Califor·

the American College of

nia, Helfert trained young

Physicians and the Roches-

doctors in Mexico and Cen·

ter Academy of Medicine.

tral America for City of Hope

Piccoli is survived by his

and donated time to the La·

wife, Bess (Gioia), and a

guna Beach Free Clinic. In

daughter, Julie Margaux

1976, he retired and moved

Kelleher.

to Laguna Hills, CA, with his
second wife, Gertrude
Kolbert Helfert, who passed
away in 1995.
Helfert is survived by
his children, Jay Helfert and
Carole Helfert Aragon and
son-in-law, Audie Aragon;
grandchildren Heather
Helfert Swerdlow and her
husband Aaron Swerdlow
and Breanna Helfert; great-

graduating in 1948. He

entered UB's medical

served a general surgery

school, after which he in-

residency at the former E. J.

terned in San Mateo, CA.

Meyer Memorial Hospital in
Buffalo and completed his

training, he opened a gen-

training at Veterans Hospital

eral practice in Hemet, CA.

in Omaha, NE. Graff

In 1954, he left his practice

enlisted in the Air Force in

to work for the Dade County

1952 and was stationed at

Public Health Department in

Mitchell Air Force Base on

Miami, where he remained

long Island, where he was

untill961. During that

chief of surgery. There, he

time, Erickson worked in the

met Mary Ellen White, a

field trials of a then-new

registered nurse, and the

oral vaccine against polio·

couple were married in

myelitis and earned an MPH

1955. They returned to

degree from Tulane Univer-

Buffalo, where he practiced

sity. In 1961, he moved to

general surgery at Kenmore

Crescent City, Fl, where he

Mercy Hospital and occupa-

practiced for a year before

tional medicine at Buffalo

moving to De land, where

Industrial Medical Center

he practiced until his retire·

until he retired in 1997.

ment in 1977. Erickson is

Besides his wife, he is
survived by a son, Jonathan,

of Madison, WI; a brother,

Deborah, of San Clemente,

Charles G. Erickson, of

CA; and three brothers,

Williamsville, NY; and a

Sanford and Harry, both of

sister, Marie T. Erickson,

Amherst, NY, and Herman of

of De land, FL.

George Erickson,
MD'49

died June 12, 2001, of
complications related to
Alzheimer's disease. He
was 70.
According to his oncology colleagues at the Uni·
versity of Nebraska (UN)
Medical Center, Foley strove
to provide the best care possible to his patients and to
keep up with research; but
it was in helping to train
future oncologists that he
took the most pride. A
native of Buffalo, NY, Foley
was first in his graduating
class at the then-University
of Buffalo in 1955.
He later earned a doctorate from the University of
Minnesota School of Medicine. He joined the UN Medi·
cal Center as an assistant
professor of internal medicine in 1963 and was named
a full professor in 1968. He
Hospice Program from 1977

Gertrude Waite
DeLaney, MD '50

to 1990. In 1994, he was

Gertrude Waite Delaney,

among 29 Nebraska physi·

George

MD '50, died in Tampa, Fl,

cians selected for the book

Erickson,

on April 18, 2001.

Best Doctors in America.

WilliamS.
Glassman, MD '51

wife, Janet; three sons,

Harold L. Graff, MD '48, a

gust 8,

retired general surgeon,

2001, in

Foley is survived by his

MD '49,

died unexpectedly on August

De land, Fl, where he lived

27, 2000, at his summer

since 1962. He was 90. A

home in Rose Hill, Ontario.

graduate of South Park High

He was 75.

in Buffalo and Canisius Col·

NY, Graff grew up on Memo·

John F. Foley, MD '55,

also served the University

Niagara Falls.

died Au·

rial Parkway and graduated

survived by a son, Matthew
George Erickson, MD, PhD,

of Amherst, NY; a daughter,

Harold L. Graff,
MD'48

Born in Niagara Falls,

Upon completion of his

John F. Foley,
MD'55

lege, Erickson worked in the
Bethlehem Steel Works in
lackawanna, NY, in the

William S. Glassman, MD
'51, died
November
8, 2001, in
las Vegas,
NV. Glass-

Peter of los Altos Hills, CA,
David of Fairview Heights,
ll, and James of Petaluma,
CA; and three daughters,
Sharon of Milwaukee, Judy
of Schaumburg, ll, and
Susan of los Angeles.

man was a
general

Spri11g

2002

I u f I a I o Phy si ci a n

�Which can
you afford
to waste?
BENEFITS

FEATURES

E-mai
I

CONTINUED FROM PAGE 46

C. White, MD. DDS '93, writes: "! am practicing emer-

gency medicine in Ravenna, OH. I am a partner in
PES, Inc. and have been practicing at Robinson
Memorial Hospital since 1997." E-mail address is
CRW36@aol.com.

• Electronic submission of all
major insurance claims

• Increase your accounts
receivable turnover

• Follow-up of all unpaid claims
and open patient accounts

• Improve collection ratio and
reduce bad debts

are delighted to announce the birth of our daughter, Naomi Hahna Kissel, on April12, 2001. We
make Madison, WI, our home and would welcome
visitors." E-mail address is: jsbae22@hotmail.com.

• Advisement on and assistance
with insurance carriers and
government regulations

• Optimize revenue through
proper monitoring of charge
master

Pamela (Crowell) Grover, MD '98, writes: "Last year I

• Choice of processing
options including on-line
or full-service

• Eliminate costs associated
with computer software and
maintenance

• Easy start-up or conversion
from present billing system

• Transition smoothly and quickly
while maintaining cash flow

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software available on request

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patient satisfaction

• Expertise on existing and new • Assure your patients' rights are
corporate compliance guidelines protected
• Gain peace of mind from
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experienced C.P.A.'s

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SPECIALISTS

50 Alcona Avenue
Amherst, NY 14226
Tel: (716) 834-1191
Fax: (716) 834-1382
e-mail: pbs50@aol.com

Gregg Kissel, MD '97, and Jean 8ae, MD '97, write: "We

graduated from the University of South Florida/
Morton Plant Mease Family Practice Residency
Program and was the recipient of the Outstanding
Family Practice Resident Award. I am currently a
junior faculty member for the program and will be
completing my fellowship in Faculty Development
at the Michigan State University Primary Care Faculty Development Fellowship in june, 2002. I am
also medical director for the Turley Family Health
Center-the outpatient site for our residency program. On May 27,2001, my husband, Will, and I
were married at Letchworth State Park, NY."
E-mail address is pgrover@tampabay.rr.com.
Hannah loon, MD '98, writes: " ! was married to

Steven lsserman on November 17, 2001. After a
brief honeymoon in Hawaii, I've resumed my
duties as chief resident in anesthesia at Massachusetts General Hospital. I am anticipating starting
an ICU fellowship at MGH in August 2002."
E-mail address is: HToon@massmed.org.

2000s
Steve Ambrusko, MD 'DO, writes: "My wife, Amy, and

I are doing well and are very excited about our
baby on the way, due in June 2002. Otherwise the
pediatric residency is going very well." E-mail
address is sj_ambrusko@hotmail.com. CD

48

luffalo Physician

Spring

2002

�Nineteenth-century shagreen

leather lancet case with four tortoise-shell handled blades. Knives such

as these were used to bleed patients. After applying a tourniquet, the physician would cut a vessel, usually
a vein, with the lancet, which he carried in a case. (Shagreen is a dyed, untanned leather or sharkskin.)
The instrument is part of the Edgar R. McGuire Historical Medical Instrument Collection, housed in
the Robert L. Brown History of Medicine Collection, Health Sciences Library, Abbott Hall, on the University
at Buffalo's South Campus.

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RY

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C A~PJS

PUS M~I L

UB's HISTORY
Of MEDICINE
COLLECTION PRESENTS
PHARMACOPOEIA

Th is illustration was digita ll y reproduced from
offizinellen Gewachse , a
four - volume edition of
pharmaceutical plants
a

and their medicinal uses ,
published in German in
I

863. The pharmacopoeia

by Otto -Karl Berg (I815 ()

c

~~afl~
..

~

I866) is part of the Rob ert L. Brown History of
Medicine Collection , located in the Abbott Hall

~

Health Sciences Library.
Pi ctured is the Cherry
Blossom , one of a series
of botanical images digi tally r estored as part of
an initiative to preserve
a nd highlight unique re sources from the library' s
coll ection.
R e production s

are

avail a bl e for purchase
through the library , and
ca n b e viewed onlin e at
iMedia. buffalo. edu/ art/ .
Image restoration was
performed by iMedia , the
instructional media ser vices

department

of

Computing and I nforma tion Techno logy, Univer sity at Buffalo .

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                    <text>�l1ffal1 P~ysicial

ASSOCIATE VICE PRESIDENT FOR
UNIVERSITY CoMMUNICATIONS

Dr. Carole Smith Petro
DIRECTOR OF PERIODI C ALS

Sue Wuetcher

Dear Alumni and Friends,

EDITOR

Stephat~ie

A.

Ut~ger

ART DIRE C TOR

&amp; DESIGN

Ala"]. Kegler

School of Medicine and Biomedical Sciences
graduated its ! 56th class, m arking yet another chapter in the histo ry of one of the oldest
institutions of m edi cal edu cation in o ur coun tr y. Anyone familiar with o ur school's
histo ry knows that its lo ngevi ty is d ue to both an adherence to trad ition and an adaptability to change. While the graduation ceremony fo r the Class of 2002 paid tribute to
trad it io n, this year's incoming class paid tribute to change by bei ng the first group of
students to complete a year of study in our new curriculum.
Th is new curriculum , which is essen tia l to our rem ai ning at th e cutting edge of
med ical educatio n, is a change that the students, for the most part, took in str ide, giving

DESIGN ASSISTANT

Karen Liclwer
CONTRIBUTING WRITERS

Lois Baker and Ellen Goldbaum
PRODUCTION COORDINATOR

Cynthia Todd-Flick
U NIVER S ITY AT BUFFALO
S C HOOL OF MEDICINE AND
BIOMEDICAL SCIENCES

Dr. Michael Bernardino, Dean

us reason to believe that we have gotten off to a good start in what we
EDITORIAL BOARD

know will be an o ngo ing process of refi nement.
While it is imperative that we immerse our students in the most modern
and effective curricul um possible, it is equally important for us to turn our
attention to other ways we can support their medical school experience.
This support can be demo nstrated in a num ber of different ways, including financia l, ca reer and psychosocial counseling, to name a few. The bottom line is that, as educators, we must establish a relationshi p with our
students that assures them we are as interested in their success as they are.
Programs that support our students require a financial investment, as well as a moral
commitment. In looking to the future, 1 anticipate that our school, like most state-assisted
schools, will not receive significantly more money from the state than what it is already
receiving, which is about 13 percent annuall y. Therefore, if we are to provide a "value-

Dr. john Bodki11
Dr. Martin Brecher
Dr. Harold Brody
Dr. Linda]. Corder
5
Elizabeth Volz, Class of 200
Dr. ]ames Kanski
Dr. Elizabeth Olmsted
Dr. ]ames R. Olson
Dr. Stephen Spaulding
Dr. Bradley T. Truax
Dr. Franklin Zep/owitz
TEA C HIN G HOSPITALS

Erie Cout~ty Medical Center
Roswell Park Cat~cer lt~stitute
Veteratls Affairs Wester"
tetll
New York Healthcare Sys
.
I
The Buffalo General Hosplta
lo
The Children 's Hospital of B4f~
Millard Fillmore Gates Hosplta "tal
Millard Fillmore Suburban Hospl
KAI.EIOA Ht .\ LT H:

added" education to ou r students it is clea r that a major issue we must devote our energy to
in the years ahead is development and ph ilanthropy. Currently, our school receives about
$200,000 a year from its alumni. I would like to see that fig ure rise to $3 to $5 mill ion.
It is important that these funds be used to enhance research efforts, to recruit and retain
fac ulty, and to bolster a discretionary fund that supports special projects that arise each
year. However, I feel it is equally important that we be in a position to use these fu nds to
support programs and services that make our students feel that they are having a positive
and worthwh ile experience. Also, because the cost of a medical education is only go ing to
increase, it is crucial that we be able to provide scholarships to high-quality students who
don't have the wherewithal to attend med ical school without financia l assistance.

Sr sTE-"'
Mercy Health System
Sisters of Charity Hospital
CA1Hou c H EAI.TII

Niagara Falls Memorial
Medical Center
@

ONIYEISITY AT IUFFllO.
TIE STliE UNIYEISITY OF NEW YOlK

If we can do these things, then today's students will be motivated to support tomorrow's students, further ensuring the integrity of a med ical school experience that has

Letters to the Editor

meant so m uch to so many people over the past century and a half.

Buffa lo Physician is published quarterly
by the University at Buffalo School o f
Medicine and Bio medical Sciences In
cooperation wi th the Office of
Communications.
Letters to the Editor a re welcome
and can be sent c/o Buffa lo Physician.
330 Crofts Hall, University at Buffalo,
Buffalo, NY 14260; o r via e-mail to
bp-no tes@buffalo.edu. Telepho ne:
(7 16) 645-5000, ext. 1387.
.
The staff reserves the right to edit
all submissions for clarity and length.

As we look to the future, therefore, I hope that you will join me and others at ou r
school to not only help define both short- and long-term goals for how we can enhance
o ur students' experiences, but to also provide the resources and support needed to see
these plans through to fruition. ) _

R..

~~£4 ./l_;_ y

.i)

M I CHAEL E . BERNARDINO.

MD . MBA

Dean, School of Medici ne at~ d Biomedical Sciet~ces
Vice Presidetlt for Hea lt h Affairs

T...:.:.... University at auffal~rk
~

TI1e State University ofNeW

�VOLUME

37,

NUMBER

t l

p

H

y

c

s

A

N

Features
Sound Science
UB scientists advance our
understanding of how we hear
and what happens when we don't
BY

LOIS BAKER

AChild Abused, but Not Forgotten
Stephen Lazoritz, MD '76,
brings the lessons of history
home to the present
by M .K. Kinnamon

David Hojnacki, MD '02, pauses to savor the long-awaited moment on stage at this year's
commencement, held on May U . For more on the day'scelebration, turn to page 22.

COVER

1&amp; Medicine
Taken to
Heart-John
Canty, MD '79,
Albert and
Elizabeth
Rekate Chair in
Cardiovascular
Disease

18 Match Day
Listing

22 Graduation
Day, 2002!

24 jeffrey Sko ln ick
amed
Director
of the Buffalo
Center of
Excellence in
Bioinformatics

I LLUSTRATION

30 Presidential
Assassinatio ns
of the 20th
Centuryup Close
and Medical

Honored for
Lifetime
Achievement

SANDRA

35 Find Your
Class and All
the Familiar
Faces from
Your Medical
School Days

OtONISI

42 News from
Your UB
Classmates and
Other Alumni

49 Spring Clinical
Day- a Collage

31 Medical Alumni
2&amp; Carl Granger

BY

Achievement
Awards

�B

I

ILLUSTRATIONS

SA ND R A

D

PHOTOGRAPHY
KC

2

BY

I 0 N IS I

BY

KRATT

laffafo Physicin

y

L

0

I

I

s

B

A

K

E

R

�n this multidisciplinary laboratory, specialists in anatomy, audiology, biophysics, engineering, otolaryngology, pediatrics, neurology, physiology, pharmacology and psychology are conducting
studies in hair-cell regeneration, drug therapy and ototoxic drugs,
noise-induced hearing loss, middle-ear disease, infant hearing
loss, central-auditory system plasticity, mechanical transduction
(the fundamental process of transferring sound energy to electrical energy), age-related hearing loss, hormonal influence on

hearing loss, and central-auditory processing in the brain.
Center scientists have generated more than $12 million in
research funding, including a highly competitive $5.7 million
multidisciplinary program project grant from the National
Institutes of Health awarded in 1999, which focuses specifically
on the mechanisms underlying acquired hearing loss.
Why is a large segment of the population becoming "hard
of hearing?"

S umm er 2 00 2

luffal1 Pbysician

3

�BOUT 10 MILLION CAN ATTRIBUTE THEIR LOSS OF HEARING TO NOISE EXPOSURE.
Listening to music through stereo headphones at top volume, for example, is as damaging to
the auditory system as the thunder of a diesel locomotive. Thirty million people in the U.S. are
exposed to similarly dangerous noise levels each day.
Infections and some cancer chemotherapy drugs also can cause deafness, but the maJor
culprit is Father Time. The National Institute on Deafness and Other Communicative Disorders
estimates that 30 to 35 percent of people between the ages of 65 and 75 have a hearing loss. The percentage
climbs to nearly 50 percent among those over 75.
For much of the 20th century, technology to improve hearing
had advanced little beyond the ear trumpet, a large cone-shaped
megaphone-in-reverse that was intended to amplify sound. That
was state-of-the-art for our hard-of-hearing great-grandparents.
Salvi, professor of communicative disorders and sciences,
neurology and otolaryngology and director of the UB Center for
Hearing and Deafness, says that until the past five to eight years,
people looked at hearing loss from a descriptive point of view.
"They measured loss-how poorly people detected speech and
other sounds, and how well they could hear in a background of
noise," he says. "That's been the situation for about the last 100
years." Only within the past two decades have hearing researchers begun to understand that hearing depends primarily on the
ability of tiny cilia on hair cells of the inner ear to transform
sound-wave energy into electrical energy, and on how accurately the brain receives and translates the resulting nerve impulses.
"The big change came with advances in biology and our ability
to study how inner-ear hair cells develop, live and die," Salvi says.
"A huge amount of work is now being done in that area, and our
lab was one of the first to get involved. Hearing research has moved from the cellular to the molecular to the genetic level."

Tracing the Path of Cell Death
Most cases of hearing loss occur when inner-ear hair cells in the
cochlea are damaged or killed. Hair cells transfer their neural
activity to the auditory nerve, which carries the nerve impulses to
the brain's central auditory system. Considerable research in
recent years has been devoted to finding compounds that might
protect against hearing loss by preventing hair-cell death or by
rescuing and repairing damaged cells.
Center researchers, collaborating with colleagues at Roswell
Park Cancer Institute, were among the first to study the process of
hair cell death-specifically programmed cell death called
apoptosis- in inner-ear hair cells. Salvi and fellow center scientists are attempting to determine what triggers the cell-death
switch of apoptosis by subjecting cultured inner-ear sensory cells
and sensory neurons to known ototoxic drugs- the antibiotic
gentamicin and cancer therapy drugs cisplatin or carboplatinand tracking the biochemical pathways involved in cell death.

4

luflal1 Pbysici11

S umm e r

2 00 2

Armed with these findings, the researchers now are using certain
drugs to try to block these pathways. The primary candidates are a
protease inhibitor called leupeptin and an
inhibitor of the tumor suppressor gene p53,
which acts a "cell executioner" of sorts.
"Gentamicin is used in the U.S. to treat
infections that arise in persons with muscular dystrophy and cystic fibrosis and is prescribed extensively in other parts of the

�world to treat a wide range of bacterial infections," Salvi says.
"Unfortunately, gentamicin causes severe deafness, so there is
tremendous interest in finding drugs that block hair-cell death.
"We have found that leupeptin does a tremendous job of
rescuing cells exposed to gentamicin. In inner-ear cultures, we
see 70 percent loss of hair cells without it, but with it we can
rescue most of those cells. We've also shown that using a p53
inhibitor, we can block cisplatin toxicity in the inner ear."
RI HASHINO, PHD, a center research assistant professor and
specialist in neuroscience, is studying the cellular mechanism
thought to be responsible for the uptake of gentamicin into the
hair cells. Her studies suggest that gentamicin is captured and sequestered in lysosomes (cell components that take up external
material in the body) for a period of time before it kills hair cells.
This finding suggests that lysosomes may be an important factor
in the cell-death process and could be targeted for intervention.
Hair-cell death due to noise exposure is the primary focus of
the work of Donald Henderson, PhD, professor of communicative disorders and sciences and otolaryngology at UB. He and
colleagues are conducting investigations into compounds that
may protect the auditory system from too much noise. They have
identified and are concentrating on a family of enzymes, some of
which trigger the death process and some that execute it.
"Now we are trying to trace the pathway of these enzymes to

following three to six hours of moderate-level noise exposure.
Initial studies indicate that even moderate noise exposure
stimulates the repair and replacement of proteins in the inner ear,
suggesting that if this repair process can be started early enough,
it may be possible to condition the ear against hearing loss.
Taggart also is investigating the potential of inherited variation in DNA sequences of the inner ear to influence an individual's susceptibility to noise-induced hearing loss. These studies,
which involve U.S. Navy personnel who work in high-noise jobs,
are assessing the possible role of genetic variation within the
specific inner-ear proteins that maintain cellular homeostasis of
the inner ear during and after noise exposure.
Taggart is targeting a group of functionally related proteins called connexins that maintain normal functioning within the inner
ear and are thought to be linked to noise-induced hearing loss.
Hearing loss due to aging, responsible for the largest cohort of
the hearing impaired, also may have a genetic component, an
avenue Robert Burkard, PhD, professor of communicative disorders and sciences and otolaryngology, is pursuing.
"Many hearing losses are genetically programmed to show up
later in life," says Burkard. "There is quite a bit of evidence to
indicate that age-related hearing loss may be a result of a genetic
inability to cleanup free radicals. If we
know that the gene turns on at, say,
60, we can be poised to do something

''The big change

their starting point," says Henderson. "If we can do this, we can
rescue, and perhaps prevent, hearing loss due to noise damage."
One enzyme being studied as a possible protectant is gluthathione peroxidase, a compound important for maintaining antioxidant activity, which in turn is essential for combating cell
damage from free radicals. "We know noise can increase formation of free radicals in the cochlea," Henderson says. "We are
investigating how this enzyme would work as a treatment in
humans, and how and when to give the drug."

The Genetics of Hearing Loss
Center researchers led by Tom Taggart, PhD, associate professor
of communicative disorders and sciences, are taking center stage
in a new avenue of auditory research: the genetics of hearing loss.
UB's center is one of the first to conduct gene-expression studies
identifying genes within the inner ear that are up-regulated in
response to intense sound stimulation. So far they have identified about 100 genes that increase their expression substantially

about it. Once we have ideas concerning the causes, we are in a
better position to approach a treatment or cure."

Tinnitus from the Brain's Perspective
UB researchers have done groundbreaking research into tinnitus, the debilitating phantom sounds known as "ringing in the
ears" that plague millions of persons, some to the point of
disability. Alan Lockwood, PhD, professor of neurology, nuclear
medicine and communicative disorders and sciences, a member of the center faculty and director of operations for DBVeteran Affairs' PET Imaging Center, was the first to identify
certain sites in the brain where tinnitus originates.
Lockwood, Salvi and Burkard now are studying volunteers
who can change their tinnitus with certain eye or jaw movements
to define further the brain regions that are involved. They also are
investigating the effects of the painkiller lidocaine on tinnitus,
as the drug is said to reduce the symptoms by up to 30 percent in
some sufferers.

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2 0 0 2

luff al o Ph pici an

5

�"We are trying to determine what is causing tinnitus from
the brain's perspective," says Burkard. "Why is the sound being
modified? Do different parts of the brain light up? We're
looking for areas less and more active that could be helping turn
off tinnitus."
Burkard, Salvi and Lockwood also are working with an experimental device that can interrupt or mask tinnitus in some
subjects through the use of ultrasonic bone conduction.
In a related project, center researchers are capitalizing on
PET's ability to track brain responses to stimuli to determine if
different brain regions are activated during noise and quiet.

The Mysterious, Pliable Brain
For other center researchers, studies in the field of brain plasticity have more immediate clinical applications. It is known
that the neuronal network responsible
for hearing reorganizes itself after
damage to inner-ear hair cells-in a

system may be important for hearing during noisy situations."
McFadden also is investigating the potential role of estrogen
as a protectant against hearing loss. Hers is the first study to look
at the hormone in this context. Working with chinchillas, she
found that noise exposure caused less damage in animals receiving estrogen than in those that didn't. These results suggest that
estrogen, like gluthathione peroxidase, may act as an antioxidant. "Men get more noise-induced hearing loss than women,
and they experience age-induced hearing loss earlier and more
severely than women," McFadden says. "In part, this may be
because men are exposed to more noise throughout life. But we
are seeing some very similar sex differences in chinchillas."
In experiments conducted before and after administering
estrogen, she found that the females were less susceptible to
noise damage at baseline, and that animals receiving estrogen
were less likely to develop hearing loss due to noise. She is now
measuring natural estrogen levels in the animals and testing
their susceptibility to noise.

"Now we are trying to trace

sense, changing the channel to get better reception.
Burkard says one explanation for this phenomenon may be
that somewhere in the brain, the inhibition mechanism that
protects the central auditory system from too much stimulus
develops a lower threshold when less sound reaches the system.
The brain's penchant for reorganizing itself may then explain
why people who receive hearing aids or implants often have
trouble adjusting to the devices.
"When people first try a hearing aid, they frequently don't
like it," Burkard says. "We think this is because the brain has
already compensated for less stimulus, and when the signal is
turned up with a hearing aid, it's bothersome; it helps to explain
people's distress. This is why it is really important for people to
stay with their devices until the brain once again adjusts to the
new stimuli." Sandra McFadden, PhD, research assistant professor at the center at UB, and Henderson have found that a
poorly understood segment of the auditory organs called the
efferent system may play a role in permanent hearing loss.
"The efferent system is the appendix of the auditory system,"
McFadden says. "We don't really know what it does."
natomically, the efferent system is a large bundle of fibers running from the brain to the cochlea that functions as a feedback
mechanism. "We' re one of the first laboratories to show that if
you cut the efferent fibers in one ear, those ears show more
damage from noise," McFadden says. "It appears the efferent

6

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Knowledge is power in nearly every endeavor, and this is
particularly true in basic scientific research. Understanding how
hearing is lost and how hearing loss can be recovered or prevented will make possible the development of new devices and
therapies that will brighten the lives of millions of people.
The future for understanding and treating hearing loss and
other hearing disabilities looks bright, Salvi says. "Drawing from
brain imaging, genetics, neuroscience, molecular biology and
biochemistry," he says, "we now have a whole arsenal of weapons at our disposal, ranging from those that allow us to look at
acquired hearing loss at the molecular level to those that let us
look at the whole brain at once."
Great-grandmother, with her ear trumpet, would no doubt
be a mazed.
CD
Additional UB scientists who have contributed to the studies
described above include Dalian Ding, Wei Sun, Xiangyang
Zheng, MD, and Bo-Hua Hu, MD, all of whom are research
assistant professors.

For more infonnation on the studies described in this article
or other major research advances made at the UB Center for
Hearing and Deafness, visit the center's web site at
http://wings.buffalo.edulfaculty/research/chdl

�SENSORY PHYS I CS AND
THE SUBSPECIALTY OF

Most hearing research and treatment to
date has concentrated on the transmitting of auditory signals to the brain-the

How Sound, Taste,

PSYCHOACOUSTICS

"sending" end. It is possible, however, for people to have trouble
hearing even when the sending mechanism is in fine shape. One
new and promising field of hearing research focuses on how
One of the theories she is following is that during hearing loss, these

and where the brain receives and deciphers certain signals from the

cells may lose their sensitivity due to lack of stimulation. "This leads us

auditory nerve.

to address a number of questions," she notes. "How plastic is the

David Eddins, PhD, and Ann Clock Eddins, PhD, both associate professors in Communicative Disorders and Sciences

By Lois Baker

(and also husband and wife), are conducting frontline research in this
area within University at Buffalo's Center for Hearing and Deafness.

brain? Are the cells in the brain being damaged? If we can provide some other type of stimulation, can they recover? Can we

stimulate them in a way that will help them respond better?"
In another approach to studying the temporal quality of sound, Eddins
is conducting PET studies on human volunteers to observe which parts of
the brain are active when exposed to auditory signals and what features
of sound prompt the brain to shift focus from one part to another.
"We are trying to understand why hearing comes easily when listening
to certain aspects of sound, while other aspects are
more difficuH," she says. "We've found that processing shifts from one side of the brain to the other,
depending on whether you are listening globally, such
as to general conversation, or locally, such as to a
teacher's instructions."
This work may help to explain why a problem student
"can't hear" even though a hearing test finds no deficit-there may be a glitch in the central processing.
David Eddins, PhD, trained in clinical audiology and
experimental psychology, studies how the intensity of a sound varies
across different frequencies, a concept called spectral processing.
"The ability of the ear to identify peaks and valleys of sound is very
important in identifying the characteristics of sound," he says. "Every
sound has a characteristic spectral pattern, which helps in identifying

They work in the field of sensory physics, which is the study of how

the source of the sound and in telling the difference between sounds,

sound, taste, smell, touch and vision are perceived, and within this

but we don't know how the brain processes this information."

larger field, in the subspecialty of psychoacoustics.

Eddins bases his research on the earlier work of vision researchers.

Ann Eddins, a specialist in auditory physiology, studies the brain's

These scientists had shown that the brain breaks down an image into

temporal processing of sound, or how sound varies over milliseconds of

many different parts, then assigns the parts to specific places in the

time. "There is a lot we don't know about how the auditory system codes

brain's visual center, where specialized cells tuned to certain spatial

time," she says. "Most people are able to process temporal variations in

frequencies become excited and create a neural representation of

sound, but in hearing loss we think people lose some of this proces-

the image.

sing abilitY."

"This discovery brought a revolution in visual science," Eddins says.

This results in sounds being smeared together, especially if the

"We think there may be a general mechanism for processing features

person is listening in an environment with background noise, Eddins

of all stimuli. Are cells in the brain tuned to certain spatial frequencies

says, which probably contributes to poor understanding of speech in

for hearing? We have found strong evidence of "tuning," and we think

the hearing impaired.

tuning can be explained by the presence of channels-groups of cells

Eddins is studying the question of how the temporal aspects of sound

devoted to different spatial frequencies of sound. This provides us with

are processed in the brain using several approaches, working with an

a basic understanding of how sound is interpreted in the brain and how

animal model. On a "global" level, she measures the electrical action

this tuning changes with hearing loss.

created by groups of cells in the brain, called evoked potentials, during

"We suspect that the evidence we and others find in this research

sound. This identifies the parts of the brain that are activated. She then

will completely change the way we think about how the central-auditory

measures responses of single neurons in the regions activated to deter-

system works."

mine which cells respond to sound duration, or to high or low frequency.

Summer

2002

l u ffa l1 Pb ysici a a

7

��BUT NOT FORGOTTE
THE WORK OF STEPHEN LAZORITZ,

MD '76,

PEDIATRICIAN, CHILD ADVOCATE AND AUTHOR

WHEN STEPHEN LAZORITZ, MD

'76,

FIRST

"MET" MARY ELLEN WILSON, IT WAS THE LATE

1960s AND HE WAS A UNIVERSITY AT BUFFALO

As

UNDERGRADUATE.

A STUDENT IN SOCIAL

WORK 101 HE LEARNED ABOUT THE 10-YEAR-

OLD GIRL, A NEW YORK CITY ORPHAN, WHO HAD

SUFFERED HORRIFIC ABUSE AT THE HANDS OF

HER FOSTER MOTHER FOR ALMOST EIGHT YEARS.

S

11 111

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2 0 0 2

llflal• nysicia•

9

�Not

FORGOTTEN

Mary Ellen was not a modern-day child, however. Born in 1864, she was a child from
another century, a time when laws accommodated the rescue of abused animals yet made no provision for
rescuing abused children. In 1874, her tragic young life became the subject of one of the most celebrated
and important legal cases of its time, a case that led to the establishment of the first child protection agency
in the United States: the New York Society for the Prevention of Cruelty to Children (NYSPCC).
Lazoritz never forgot the little girl whose suffering resulted in a landmark child protection case. Years
later, as a pediatrician with expertise in child abuse, he picked up the thread of Mary Ellen's story and
embarked on a 15-year quest to find out more. In 1988, his perseverance and a few serendipitous occurrences yielded a book titled Out of the Darkness: The Story ofMary Ellen Wilson, now in its second printing.
A Simple Twist of Fate

window, along with books and files, and the crowd chanting 'off

Today, as vice president for medical affairs at Children's Hospital

ROTC.' Eventually, this and other action by vocal students and

in Omaha, Nebraska, Lazoritz can look back on a career in which he

faculty led to the program being discontinued."

has dedicated more than 20 years to abused and neglected children.

As a result, Lazoritz, who had been accepted into the Air Force's

Despite this remarkably long tenure in a field noted for its quick

pilot training program with high honors, had to decide whether

burnout, Lazoritz did not enter college at the University at Buffalo in

he would transfer to a ROTC program at another university, or

1968 with a driving desire to become a physician. As an undergrad-

stay at UB and declare a new major. Eventually, he decided to stay
at UB and pursue studies in sociology and pre-medicine. To catch

uate in Air Force ROTC at UB, he had pretty much decided on a
career as a pilot. However, his experience as a hospital volunteer

up with his coursework in these areas, he attended summer

while in high school had also sparked an interest in healthcare,

school for two years, an effort that paid off when he was admitted

which prompted him to take classes in social work.

to UB's School of Medicine in 1972.
In his third year of medical school, Lazoritz completed his

"UB's social work department back then was radical. And there
I was, a politically conservative sophomore in my ROTC uniform,"
Lazoritz recalls. "So, needless to say, I didn't really fit into social
work at that time."

pediatric rotation at Mercy Hospital in Buffalo, where he met
faculty who inspired him to make a lifelong commitment to
working with children. "! had some really great preceptors who
had a big influence on my life," says Lazoritz.
In particular, he remembers UB clinical professors of pediatrics

Although he didn't know it in 1987,
t

return to Buffalo
ing more of the

Mary Ellen mystory. Upon learning that the child was
ventually placed with a family who lived near Rochester,
ew York. he made several trips there to investigate.

joseph Mattimore, MD, and Chelikani V. Varma, MD. "These
physicians and the staff at Mercy showed me that working with
kids was a fun thing to do," he recalls.

On-the-Job Training
Upon graduation in 1976, Lazoritz began a 10-year stint in the
United States military, during which time he served in both the
Navy and Army. After completing his residency in pediatrics at the
Naval Regional Medical Center in Portsmouth, Virginia, in 1979,

10

Ultimately, anti-Vietnam sentiments on campus culminated in
events that forced Lazoritz to make a tough decision about his career
plans, a decision that put him on a path to becoming a physician.

he began his pediatric career at the Naval Regional Medical Center
in Orlando, Florida.

"One afternoon a crowd looted the ROTC office in Clarke
Gym," he recalls. "! remember a Xerox machine flying out the

abused children. A turning point in his exposure to these cases

laffala Pbysiciaa

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2 00 2

As a pediatrician, it was inevitable that Lazoritz would encounter
came one day while he was working with a group of psychiatrists

�and overlooked documents. During his tenure as assistant professor of pediatrics at the Uniformed Services
University in Bethesda, Maryland, from 1981 to 1987, he
used his free time to search the Library of Congress for
information on her case. Finding newspaper articles
from 1874 that documented the court trial was easy, he
says, but what he really wanted to discover was who her
descendants were and how her life later unfolded.
On a trip to the National Archives he met a man who
gave him a crash course on how to conduct genealogical
research, which led to a major breakthrough.
performing evaluations of abused kids in Orlando.
"On my first day, I got paged to the emergency room to see a
child abuse case, and my boss said, 'Oh, by the way, you're also on
the child abuse team,"' recalls Lazoritz.

"I found out that Mary Ellen had gotten married, and !learned
what her husband's name was," recalls Lazoritz. "Then I started
looking through years of obituaries to find out when he died so I
could get a list of their descendants."
In 1987, Lazoritz, his wife, Mary, and their growing family (which

"When I saw that first patient, which was a sexual abuse case, I
realized that I didn't know what I was doing, and I knew I had to

eventually numbered six children, including a daughter named

learn," he continues. "Until the late 1970s and early 1980s, we didn't

Mary Ellen) returned to Buffalo, where he joined the UB School of

know much about sexual abuse. Those of us working in the field at

Medicine and Biomedical Sciences as an assistant professor of

the time had to teach ourselves and learn in an informal way from

pediatrics, a position he held until 1992. During this time, he also

other people who knew what they were talking about."
Lazoritz soon discovered that the "other people"
who knew what they were talking about often were
the allied healthcare professionals involved in the
abuse cases.
"One of the things that intrigued me most about
working in the area of child abuse is that you were a
member of a team that could include social workers,
psychologists, law enforcement officers, lawyers, or
prosecutors. And we all had to share information; this
is one of the tenets for this field. For example, early in
my career I didn't know as much about child abuse as the social
workers, nor did I know about the social work aspects of interven-

served as director of pediatrics at Erie County Medical Center,
where he established the hospital's first child sexual abuse clinic

ing in child abuse cases. I had to learn all this in order to be on
common ground with them."

(sec related article on page 15).
Although he didn't know it in 1987, his return to Buffalo moved

To this day, teamwork has remained an integral part of
Lazoritz' work ethic.

Lazoritz literally closer to solving more of the Mary Ellen mystery.

History in the Making
In 1980, Lazoritz began giving presentations in Orlando to educate
the public about child abuse. One day in 1983 while researching a

Upon learning that the child was eventually placed with a family
who lived near Rochester, New York, he made several trips there
to investigate. Not only did he find Mary Ellen's grave, but he also
found a school that was named after one of her daughters,
florence Brasser, a renowned teacher in the area.

lecture, he again encountered the scant, but extremely moving,

In talking with the school's principal, Lazoritz was elated to Jearn

details of the Mary Ellen Wilson story.
"Right then I decided that I had to know as much as I could about

that Florence Brasser was still alive and living in a nearby nursing

this girl. It became an obsession," recalls Lazoritz. "I kept thinking

information that eventually gave him access to the original files from

of her as a child, the way she was in 1874, and I believed there were

the Mary Ellen case that were stored in a box in the basement of the
NYSPCC in Manhattan.

real insights and lessons that could be learned from her story."
Lazoritz credits "serendipity and divine providence" for helping
him painstakingly reconstruct :V1ary Ellen's history from scattered

home. He visited the 86-year-old Brasser and was able to gain

"My meeting with Florence Brasser basically unlocked all kinds
of clues and information," says Lazoritz.

S11mmer

2002

lulfa l l npicill

11

�'ot FORGOTTEN

1

A Chance to Finally Tell Her Story
In September 1989, eager to share his latest findings on the case,
Lazoritz published "Whatever Happened to Mary Ellen?" in the
journal Child Abuse and Neglect. A subsequent article about her in
American Heritage magazine, which mentioned Lazoritz's research,
caught the attention of Eric Shelman, a playwright and fiction
writer who lived in Southern California. Shelman had earlier become interested in Mary Ellen's story after reading about her case
in a book of little-known facts.
In 1991, Shelman contacted Lazoritz via e-mail and the two men
began communicating by phone and computer. Eventually they
decided to combine their talents to finally tell Mary Ellen's story.
"I did most of the research and some of the writing; Eric did the
majority of the writing," says Lazoritz. "We were equal partners: I
couldn't have done it without him, and he couldn't have done it
without me."

"Until the late 1970s and early 1980s,

didn't know
orking in the

Milwaukee, where, in 1997, he was appointed associate professor.
In 1998, seven years into their collaboration, Lazoritz and Shelman finally met, a year before Out of the Darkness was published.

Unique Opportunity to Advocate for Children
In the late 1990s, after more than two decades of working on the
"front lines" with cases of child abuse, Lazoritz began to feel that his
job's high stress level was exacting a toll.
"Some people can take a daily dose of the worst that our world
has to offer without getting bitter, disillusioned or burned out," he
says. "However, I found myself getting bitter, hostile and angrylosing my objectivity and becoming part of the problem.
"I like the term 'compassion fatigue,"' he adds.
In 2000 Lazoritz left Wisconsin for his current position as vice
president for medical affairs at Children's Hospital in Omaha, where
he also serves as clinical professor in Creighton University School of
Medicine's Department of Pediatrics and as adjunct professor in the
University of Nebraska Medical Center's Department of Pediatrics.
In his leadership role at Children's Hospital, he feels he has a
unique opportunity to advocate for children. "My job is to be a

field at the time had to teach ourselves and learn in an

facilitator, to provide the medical staff with the tools they need to do

informal way from other people who knew what they

their work, and to look at the medical needs of the community to
see how we can better serve them," he says.

were talking about."

Collaborating by e-mail, phone and fax, the two created a work
of "historical fiction" that is firmly grounded in facts. Initially,
Lazoritz was reluctant to include even an iota of fiction; however,
Shelman convinced him that a strict reading of court transcripts,
dates, and data would not do justice to the story.
Having the complete original court transcript of the case was
crucial to retelling the story, as it supplied the authors with dialogue in a realistic context. Still, Shelman's storytelling expertise
was needed to recreate the settings and thoughts of the characters, as was the assistance of a
historian whom the writers employed to review the book for accuracy. For his part, Lazoritz
walked the streets of New York
and gathered factual information about the neighborhood
settings described in the book.
In 1992, when his collaboration with Shelman was just beginning to gain momentum, Lazoritz
left Buffalo for a position as assistant professor of pediatrics at the
Medical College of Wisconsin in

"As an administrator at a children's hospital," he continues, "I get a
dose of the best that our world has to offer: a team of dedicated professionals working tirelessly to save lives or make children's lives better."
While awareness and activism against child abuse has grown
tremendously in the past 30 years, the fight to protect children is far
from over, says Lazoritz, who points out that an average of three
children die from abuse and neglect in the United States every day.

One Person Helping One Child
During his career Lazoritz has been a keen observer of how the
medical profession reacts to child abuse cases, and he hasn't always
liked what he's seen. "The issue
is not identifying child abuse,"
he stresses. "For 10 years, every
physician licensed in New York
State has had to take a course in
identifying and reporting child
abuse. Unless they were sleeping,
they have had the facts. The real
issue is taking a stand."
Physicians, he says, deny
child abuse or don't report it for
a number of reasons: "For example, they don't want to get
involved, don't want to go to
court, don't believe that a family they are well acquainted with

I
12

l1ffala Ph ysician

Summer

2002

CONTINUED

ON

PACE

14

�children, Wheeler and Bergh rescued Mary Ellen by relying on
laws written to protect animals from inhumane treatment.
As a result of the Mary Ellen case, Bergh later went on to
found the New York Society for the Prevention of Cruelty to
Children INYSPCC).
Before the creation of the NYSPCC, child abuse and neglect was considered a family matter; challenging parents or

Ellen7

intervening on behaH of a child was unheard of. The land-

•

mark case of Mary Ellen Wilson forced
society to accept a moral responsibility to
protect children, even from their parents, and
many states followed New York in making
child abuse illegal.

The Story of Mary Ellen Wilson by

In April 1874, Mary Ellen's foster mother, Mary Connolly,
was convicted of felonious assault and sentenced to a year in

the first child in America to be legally removed from an abusive

the penitentiary at hard labor.

home. Born in 1864 in the New York City tenements of Hell's

In June 1875, Mary Ellen

Kitchen, Mary Ellen was only two months old when her father

was placed in the care of Etta

was killed in the Civil War, leaving her mother destitute.

Wheeler's sister, Elizabeth,

Unable to care for her daughter, Fanny Wilson was forced

and grew up in the country

to find others who could. When Fanny later died of consump-

outside of Rochester, New

tion, Mary Ellen was placed in a home where she was horribly

York. She eventually married

abused by her adoptive parents. She was beaten with a rawhide

and had two daughters who

whip almost daily, forced to sleep on a piece of carpet on the

are remembered as educated,

floor of a closet, burned with an iron, cut with sewing scissors,

successful and compassion-

and sexually abused by her foster father. Clothed only in a

ate women. Mary Ellen Wilson

tattered and tom dress she wore in all seasons, she was finally

died in 1956 at the age of 92.

rescued at age 10.

Out of the Darkness, The

The two extraordinary people who came to Mary Ellen's

Story of Mary Ellen Wilson, is

rescue were Etta Wheeler, a social worker who served victims

available at online booksell-

of poverty in the tenements, and Henry Bergh, who in 1866

ers; or it can be purchased

founded the American Society for the Prevention of Cruelty to

directly from its publisher,

Animals IASPCA).
Because there were no laws in 1874 to protect abused

Dolphin Moon Publishing, at
dolphinmoon.com.

Summer

2002

1111111 Pbysicin

13

�FORGOTTEN

CONTINUED

FROM

PACE

12

could be abusive, or they don't want to cause trouble for the family."
Lazoritz's hero, C. Henry Kempe, a researcher, teacher, pediatrician and pioneer in the field of child abuse and neglect, was outspoken in what he believed a physician's role should be. "Since
1961, when Kempe said 'physicians have a duty and a responsibility
to identify abuse and prevent its likely recurrence,' the medical
profession has had this responsibility," says Lazoritz.

Child Abuse Resources
The Child Abuse Resources page

The American Professional Society on the Abuse of Children (APSAC)

Another factor that affects the issue of effective intervention is
the differing ways a culture views child abuse over time. "Child
abuse is defined by society. Some of the things that we now call
child abuse would not have been labeled this 100
years ago, or even 20 years ago,'' explains Lazoritz.
"As societies advance and become more sophisticated, they identify things as child abuse that other
cultures wouldn't. Too, we're identifying abuse more
often because we're looking for it."
In addition to a rise in child abuse cases due to
more strenuous reporting, the incidence of abuse is
increasing due to societal changes. The biggest
change, Lazoritz feels, is in the increased numbers of
single-parent families and teenage pregnancies. "An

MARv ELLEN
AT AGE

16

art icle titled 'Infanticide' in the October 22, 1998, issue of the New
The International Society for Prevention of Child Abuse and Neglect
(IPSCANI

England journal ofMedicine stated that the highest risk factors for an
infant being killed in his or her first year oflife are a maternal age of
less than 19 and less than 12 years of education," he explains. "The
number of single teenage mothers has gone up, and therefore I think
that's why serious child abuse has gone up."
Another disturbing risk factor in abuse cases-and the subject of
an abstract Lazoritz coauthored-is a boyfriend or husband who is

The National Clearinghouse on Child Abuse and Neglect Information

not the child's biological father. In the abstract, Lazoritz cites a 1998
study showing that the rate for child physical abuse committed by
mothe rs' boyfriends lies somewhere between 16 and 25 percent.
Another form of abuse is the subject of Lazoritz's latest book,

Shaken Baby Syndrome: A Multidisciplinary Approach, which he coedited with Vincent). Palusci (Haworth Press, November 2001).
"! can't say there's a direct cause-and-effect relationship
between early childbearing age and infant homicide, but there
certainly is a strong correlation,'' he says. "We can tell people never
Prevent Child Abuse America

to shake a baby, but if we can get teenagers not to have babies,
that would be more effective."
Ultimately, Lazoritz hopes his work reflects and inspires a passion for helping children. "We are at a point now where each
physician who deals with children should ask: 'What more can I do

Compiled by Pamela M. Rose, MLS, Health Sciences Library,
University at Buffalo, 3435 Main St., Buffalo, NY 14214.
(716) 829-3900 x129; pmrose@acsu.buffalo.edu.

to prevent abuse? How can I advocate more for this child who has
been abused? How can I do more to help this abused child heal?"'
Again, he recalls a quote from Kempe: "It is just not possible to
worry about all of the needs of all of the children all of the time.
There lies frustration and total inaction as well. "
What should be learned from the Mary Ellen story? "Each one
of us must have our own 'Mary Ellen,"' says Lazoritz. "One person
helping one child at a time can make a difference."

1 1 1f al1 Hysicin

S u m m er

2002

CD

�~Uo.;'JW'"""'tl when a child

living in Buffalo or the surrounding area
was discovered to be sexually or physically abused, he or she was referred to

·nOur Own ackyar

the only physician in town who was providing medical care for these emergent

Coyne is paid

by

Kaleida Health System's
Children's Hospital of
Buffalo to treat patients
through CATS.

FURTHERING THE WORK OF STEPHEN LAZORITZ

Niagara

tor of pediatrics at Erie Country Medical
Center and a University at Buffalo assistant professor of pediatrics.

"Steve not only would see the children medically, he also would very

In addition, he treats
children at the CAC of

cases: Stephen Lazoritz, MD, then direc-

pital; the former is more of a justice model, where children

needed to do," says Jack Coyne, MD '85, clinical associate professor of

are primarily advocated for through the court system.

pediatrics at UB, and medical director of the Child Advocacy Centers of

Each week, Coyne treats 10 to 12 children at the
Child Advocacy Center of Erie County, or about 600 a year.

In 1992 Lazoritz left Buffalo for a position with the Medical College

"That's medically speaking," he emphasizes. "From

of Wisconsin in Milwaukee (see article opposite), and Coyne stepped

there, the children are seen therapeutically, and CATS

in to fill the vacancy he left.

advocates on behalf of the children for a wide variety of

On several occasions in the early 1990s, Coyne traveled to Milwaukee

reasons."

to train with Lazoritz in how to medically treat children who had been

In addition to the efforts of Lee Anthone, Coyne

sexually or physically abused, and since then the two physicians have

says, "Our community wouldn't be where it is today in

maintained a close friendship.

this process if it hadn't been for the work Steve Lazoritz

"Steve taught me the process for physically examining the children,

did while in Buffalo. By educating the community about

as well as how to talk to them and how to document what I saw," says

the medical exam we can provide for sexually abused

Coyne. In addition to treating abused children, Coyne also picked up

children-and what we can do with these exams-

where Lazoritz left off in attempting to better organize how the chil-

Steve showed how we can really help the children."

dren's cases were responded to in Buffalo by a multidisciplinary team of

Prior to Lazoritz's educational efforts, instead of

professionals that included child protective services, police and district

abused children being allowed to begin healing after

attorneys. At the time, disputes over areas of responsibility were result-

intervention, they were often subjected to a series of

ing in less than optimal intervention strategies for the children.

court-ordered physical exams-sometimes four or five

"For two years, we met as a group in an attempt to discover common
ground so that the process of evaluating these children and advocating

by different individuals and as late as nine months
after the initial intake exam.

for them wouldn't be one that was detrimental to their well-being," says

"Now we have colposcopy and we can document

Coyne. "In order to do that, we had to get on the same page and give up

with video and still photography for the medical record,"

things that we in our separate disciplines were doing, and that's exactly

says Coyne. "So if a defense attorney contests evidence

what happened."

that's being presented and wants another opinion, he

In 1994, as a result of these meetings, the Child Advocacy Center
(CACI of Erie County was established in Buffalo on Delaware Avenue;

can get it by having a physician look at the film and not
by traumatizing the child with another exam."

three years ago, it moved to its current location at 556 Franklin. Since

Despite such progress, there is still much work to be

that time, more than 300 such centers have been established in the

done in the area of child abuse in our region, Coyne

United States, including 14 in New York State.

stresses. "Right now, the only entity that 'owns' this

According to Coyne, much credit for this effort goes to the late Lee

whole process is CATS; in many cases, our healthcare

Anthone, the wife of Sidney Anthone, MD '50, a Buffalo general surgeon.

system is just doing what it needs to do and no more.

"Lee Anthone took this work upon herself as a citizen in an effort to

Getting the community involved with ownership-that's

try and make something happen. She helped facilitate the whole process," says Coyne.
The Child Advocacy Center of Erie County is part of the Child and
Adolescent Treatment Services (CATS), a local nonprofit social and

and

according to Coyne, and is affiliated with Niagara Falls Memorial Hos-

effectively advocate for them by going to court or doing whatever he

Erie, Niagara and Genesee counties.

County

the CAC of Genesee County. The latter operates along a hospital model,

the most important thing now," he says.
For more information on the Child Advocacy Center of

~

Erie County, contact Edward Suk, CSW, director, at (716) 886-5437,
or e-mail him at sukedward@aol.com.

therapeutic agency.

Summer

211112

laffale Hysician

15

�ALUMNl

MEDICINE,
ibernating myocardium i.
a condition causec1
by the progressiv£
narrowing of th£
heart arteries, re·
suiting in chronic
reduction of blood flow tc
t-ho hPtJrt

M. CANTY
MD '79, ALBERT

JoHN

While contraction of the heart is depressed, the heart tissue remains viable.
Since function can improve if blood flow
is restored, it is a reversible cause of
heart failure.
At the University at Buffalo School of
Medicine and Biomedical Sciences, John
M. Canty Jr., MD '79, and colleagues in
the Center for Research in Cardiovascular
Medicine are investigating ways in which
the heart adapts to chronic reductions in
blood flow. Their goal is to discover techniques by which this condition can be
diagnosed and to devise new therapies to
improve heart function.
Canty, a professor in UB's departments
of medicine and in physiology and biophysics, recently received a four-year,
$700,000 grant from the Department of
Veterans Affairs to support a study in
which he is using gene transfer by injecting the heart with experimental viruses
that contain vascular growth factors in
order to try and stimulate development of
new or existing blood vessels in the hibernating porcine model.
"Over the last several years, there has
been intense interest in developing angio-

JR.,

A~D ELIZABETH

KATE CHAIR IN
.ARDIOVASCULAR
DISEASE

16

laffalo

Phpiciaa

S umm e r

H111,r!P

2 00 2

genic gene transfer therapies to stimulate
the development of the coronary collateral circulation as an alternate approach to
care for patients with inoperable coronary
artery diseases," says Canty. "This investigation will identify the ability of different
therapeutic strategies to improve collateral perfusion and reverse chronic ischemic
left ventricular dysfunction."
This study is just one of a number of
funded investigations currently being
conducted by Canty, who is internationally known for his work in the area of
chronic adaptations of the heart to ischemia, according to Robert Klocke, MD,
chair of the Department of Medicine in
UB's School of Medicine and Biomedical
Sciences. In addition to the VA grant,
Canty's support includes two grants from
the National Heart, Lung and Blood Institute (NHLBI) that total $3.2 million.
"At the present time, we have very few
options other than cardiac surgery or
interventional cardiac catheterization to
improve blood supply to compromised
cardiac muscle," explains Klocke. "Dr.
Canty's work has the promise of providing alternate means of improving cardiac
blood flow in all patients with heart disease, not just those who are well enough
to tolerate invasive procedures."
In recognition of his ongoing contributions to research in cardiovascular
medicine, Canty was appointed as the
Albert and Elizabeth Rekate Chair in
Cardiovascular Disease in UB's School of
Medicine and Biomedical Sciences in
January 2001 (see article, opposite).
"It is a tremendous honor to have been
appointed the Rekate Chair," says Canty.

�"Since its inception nearly 20 years ago,
the Rekate endowment has been instrumental in facilitating a steady expansion of
the cardiovascular research programs at
UB. It has allowed us to support a number
of talented physician/scientists pursuing
basic research in cardiovascular medicine
in Buffalo."
A native of Buffalo, Canty received his
bachelor's degree in biomedical engineering from Rensselaer Polytechnic Institute
in 1975 and his medical degree from UB
in 1979. After training in internal medicine at the University of Rochester, hereturned to UB as a cardiology fellow and
joined the full-time faculty in 1983. In
1995 he was named professor of medicine
at UB and in 1996, professor of physiology and biophysics. Currently, he also
serves as associate chief of the Division of
Cardiology and is director of the Cardiac
Care Unit at Erie County Medical Center.
Canty has received numerous academic
awards, including membership in Alpha
Omega Alpha, the James A. Gibson Anatomical Society and the Tau Beta Pi Engineering Honorary Society. In 1982 he

received the John C. Sable Memorial Fund
Award and in 1983 was named a Sinsheimer
Scholar. He was also the recipient of a
Clinical Investigator Award from the National Institutes of Health's HLBI.
In addition, Canty has held numerous
memberships on national committees of
the American Heart Association and has
received consecutive four-year appointments to the Cardiovascular-Renal Study
Section of the NHLBI. He has also served
on the editorial boards of the American
journal of Physiology, Circulation Research
and the journal of Cardiovascular Pharmacology and currently reviews manuscripts
for numerous other journals, including
the New England journal ofMedicine. He is
a Fellow of the American College of Cardiology, the American College of Physicians
and the American Heart Association.
An active teacher and speaker, Canty
has mentored over 20 undergraduate students and postdoctoral trainees and has
accepted many invitations to speak at recognized centers of cardiovascular excellence worldwide and to chair national and
international meetings. 4D

1 he Albert and
Elizabeth Rekate
was established in 1982 to support and
strengthen the educational and research
activities of the Division of Cardiology in
the University at Buffalo School of
Medicine and Biomedical Sciences.
Albert C. Rekate, MD '40, has served
UB in a number of capacities, including
professor of medicine, director and acting
chair of the Department of Rehabilitation
Medicine, acting dean of the School of
Health Related Professions, and associate
dean. Since 1995, he has also served as a
member of the Dean's Advisory Council for
the School of Medicine and Biomedical
Sciences.
In 1999, the Albert and Elizabeth
Rekate Chair in Cardiovascular Disease was
augmented by the Willard H. Boardman,
M.D., and Jean Boardman Endowment.
William Boardman, a retired cardiologist,
earned a medical degree from UB in 1944;
his wife, Jean, earned a B.A. degree in biological sciences from UB in 1948.

4D

CRoss-DisCIPLINARY CoLLABORATIONS
m the cent r is their poten

estern New

c app 1c

for Research in Cardiovascular Medicine has a

tion to the development of new diagnostics and

York Healthcare System. Fallavolhta has re

broad interest in integrative cardiovascular bi-

therapies for patients w1th chronic coronary ar-

ceived a three-year, $390,000 grant from t

ology. By combining investigatiOnal stud1es di-

tery disease, accordmg to Canty. "In this regard,

Department of Veterans Affairs to support a

rected at understanding pathophysiological

we collaborate closely w1th the UB-VA Center for

study he 1 conductmg to determme wh1ch

mechanisms m the intact heart with stud1es

Positron Em1ss1on Tomography, as well as w1th

cardiac tests are most useful in pred1ctmg

aimed at

tter understandmg the basic bio-

bas1c scientists in the School of Med1cine and

those patients w th coronary heart d1s ase

chemical mechamsms at the molecular level,

who w1ll benefit most from surgery.

the program emphasizes research that can

Biomed1cal Sciences," h says.
"The translational nature of the research

translated from the laboratory to the beds1de.

giVes us the opportunity to test the concepts we

the heart improve clmically when blood flow

"The central theme of our research is fo-

know to be mechanistically involved based on

1s restored by cardiac bypass surgery, accord-

cused on understandmg chronic adaptive re-

pnor laboratory work with patients who have car-

mg to Fallavolhta. "However, m patients w1th

sponses of the heart to repetitive ischem1a

diovascular d1sease," adds Canty. "Many of the

coronary artery d1sease, chromcally dysfunc-

ar to that occurring m chronic coronary

expenmental approaches that we use are iden-

tional myocardium

artery d1seases," says John M. Canty Jr., MD,

tical to those used m the care of patients w1th

coronary revascul rlzation can improve left

Albert and Elizabeth Rekate Chair in Cardio-

chronic cardiovascular d sease."

ventricular function, symptoms and mortal-

si

vascular D1sease at UB and director of the
university's card logy research programs.
A key feature of all research projects with-

At present, Canty is collaboratmg on myocar-

Not all patients wsth poor blood flow to

IS

frequently v1

le and

ity. Therefore, the abihty to identify th1s via·

dial hibernation studies with James Fallavolhta,

bility m patients, prospectively, is of great

MD, assoc1ate professor of medicme at UB, who 1s

chnical importance," he says

Su mm er

2002

lulfalo Hysiciu

11

�MEDICAL

ScHOOL

N

E

w s

a
This yea
National Residency Matching Program
(NRMP) results were announced on March 21.2002. Thirty percent of
University at Buffalo's graduating medical students will stay in Buffalo
to train in the Graduate Medical-Dental Education Consortium,
while 46 percent will go out of state.
"For the first time, the NRMP has not provided data on choices," says
Nancy Nielsen, MD, assistant dean for Student Affairs in DB's Office of
Medical Education. "However, polling our students reveals oustanding
results, with over 60 percent receiving their first choice and over 90
percent matching in their top three choices."
Nationally, match results indicate adecrease in residency positions
filled in six primary care specialties: family practice, internal medicine,
pediatrics, medicine/pediatrics, internal medicine primary and pediatrics
primary. There were 373 fewer U.S. seniors filling these generalist
residency positions, with 2051ess positions filled overall.
Some specialty areas experienced an increase in match rates compar·
ed to last year, including anesthesiology, which had afill rate of 95.1
percent-a 7percent increase over last year; and physical medicine and
rehabilitation, for which the fill rate increased from 77.3 percent to
90.4 percent. Diagnostic radiology filled an additional44 PGY-2 positions
this year, while there was aslight decrease in U.S. medical school seniors
matching to general
surgery positions.
Overall, 23,459
individuals partici·
pated in the match this
year. Active U.S.
medical school senior
applicants enjoyed the
highest percentage of
matches to first·year
residency positions.
with a94.1 percent
match rate.
Nazaneeo Grant learns she is gaing to
Geargetown to train 11 surgery.

Amodeo, Victoria

Blitshteyn, SYetlana

U ROCHESTER/STRONG MEM-NY

UN i v BuFFALO GRAD MED-N Y

Applebee, Garrick
UVM/FLETCHER ALLEN-V T

Ariyaratana, Suzie

lulfal1 Pbysiciaa

Summer2002

LOYOLA UN I VERS ITY
MEDICAL CTR- I L

UN I V NoRTH CAROLINA HosP

Brennen, Dnid

Auerbach, Marc
SAUS H EC/ B ROOKE ARMY
NYU SCHOOL OF MED ICINE

MED CTR-TX

Azodo, Uchendu

Brooks, Victoria

M OREHOUSE SCHOOL OF
MED IC I NE-GA

UN I V BUFFALO GRAD MED-NY

Beaman, Antoinette

Brunetti, Vito
r
BETH I SRAEL MED CTR-

y

MERCY H OSP- P ITTSBURGH-PA

Beaman, Shawn
UN I V H EALTH CTR OF
PITTSBURGH- P A

UN I V H EALTH CTR OF
P I TTSBURGH-PA

ALBERT E I NSTE I N COM-NY

Bullaro, France sa
UN I V H EALTH CTR OF
P I TTSBURGH-PA

Burke, Mark

Beatty, Matthew
UNIV BUFFALO GRAD MED-NY
UN I V BuFFALO GRAD MED-NY

Carlin, Matthew

Belani, Shaleen
SUN Y H SC-SYRACUSE-NY

W I LLS EYE H OSP I TAL-PA

Belli, Lily

Chang, Jerry
LONG I SLAND ) EWISH-NY

Choe, Hana
LENOX H I LL H OSP ITAL-NY
W I NTHROP-UN I V H OSP-NY

Binder, DaYid

U SouT H ERN CA LI FORN I A

Chopra, Liza
UN i v BuFFALO GRAD MED-NY

CAMBRIDGE H osP/C H A-MA

NEW ENGLAND MEDICAL CTR-MA

18

MAYO CLIN IC- ) ACKSONV I LLE

BojoYic, Branko

�Asuccessful couple'smatch takes Jay Mepani
and Rachel Kozower to Case Western
University's Metrohealth Medical Center.

Francesca Bullaro and friends celebrate news
that she will train in pediatrics;Margo McKenna,
leh, was aresearch scholar at the NIH last year.

Hennon, Mark

Chu, Alvina

ALLEGHENY GEN H osP-PA

UN1v OF CHICAGO HosP- I L

DeiBroccolo, Jennifer

Fleming, Emily

Hinchey, Paul

Chung, Jeffrey
y

STONY BRooK TEAC H H asP-

Y

Foresta, Christopher

Hineman, Ashley

NYP HOSP-COLUM PRESBY-NY

WAYNE STATE UNIV-M I

W I NTHROP-UNIV H osP-

Den Haese, Diane

Collure, Don
UNIV BuFFALO GRAD MED-NY

P HOENIX C HI LD/MAR ICOPA-AZ

UN I V MARYLAND MED CTR

MART I N L K I NG ) R/DREW-CA

Dischner, Kurt

Conklin, Jeffrey
METROHEALTH MED CTR-0H

MEM SLOAN- K ETTER I NG-N Y
YU SCHOOL OF M ED ICINE

Gordon, Kelly

THOMAS ) EFFERSON UN I V-PA

Domaracki, Beth

Connery, Cristine

NYU Sc H OOL oF MED I C I NE

H ARTFORD H os PI TAL-CT

OHIO STATE UN I V MED CTR-O H

Grant, Gavin

Courtright·Orr, Caryn

EMORY UN I V SOM-GA

Dwyer·Matzky, Keely

UN I V BUFFALO GRAD MED-

y

UN I V BUFFALO GRAD MED-N Y

Horn, Scott
B ETH I SRAEL MED CTR-NY

NYU SCHOOL OF MED IC I NE

U CoLORADO SOM-DENVER

Hrycelak, Michael

Grant, Nazaneen

Cuomo, Linda
NYP HosP-

CooK CouNTY H oSP ITAL- I L

Dufort, Elizabeth

UN I V BuFFALO GRAD MED-NY

Holder,Amy

MARY I MOGENE BASSETT-NY
CooK CouNTY H oSPITAL- IL

Corvino, Timothy

Hoghooghi, Alexander

Hojnacki, David

Gore, Robert
UNIV BuFFALO GRAD MED-NY

Hines, Ryan

Gittleman, Alicia

ST. V I NCENT MERCY MED-O H

y

Y

YU SC H OOL OF MED IC I NE

DeSantis, Melissa

Cone, Jesse
COLUMBIA BASSETT-

UN I V BUFFALO GRAD MED-

UN1v NoRTH CAROLINA H osP

WILSON MEM REG/UHS-NY

UN IV H OSPS CLEVELAND-O H

U ROC H ESTER/STRONG M EM-NY

Y CoRNELL-

Y

Dayrit, Marivic
N SHORE U-MANHASSET-NY

De Jolla, Daniel

GEORGETOWN UNIV H osP-DC

Elliott. Darianne

GEORGETOWN UN I V H OSP-DC

N S H ORE U-MAN H ASSET-NY

Gregory, Charmaine

Figueroa, George
UN I V BUFFALO GRAD MED-

Filipink. Robyn

y

UNIV BuFFALO GRAD MED-NY
STONY BROOK TEACH HosPs-NY

UN I V H EALTH CTR OF
PITTSBURGH- P A

Filsinger, Daren
CEDARS-S I NA l MED CTR-CA

UN 1v BuFFALO GRAD MED-NY

Janis, Gregory

DUKE UN I V MED CTR-NC

Gupta, Anjeli

E1 NSTE I N/MONTEF IORE-NY

Kader, Michael

UN1v BuFFALO GRAD MED-NY

Defazio, Jennifer

Huebschmann, John

CLEVELAND CL I N IC FOUNDATIONO H

U ROCHESTER/STRONG MEM-

Y

Kam,Steven

Hebrank, Jessica
£1 NSTE I N/M ONTEF IORE-NY

W I LSON MEM R EG/U H S-NY

UC SAN FRANCISCO-CA

Summer

2002

l 1 f f af • H ys ic iaa

19

�M

E

C

D

A

L

N

SCHOOL

E

w

Ab1g sm le for
Hana Ch e, who
IS on ber way to
the Umversity of
Southern California
to train in general
surgery.

S

Katona, Kyle

Lee, Angela

Lundgren, Janell

N SHORE U-MANHASSET-NY

U

UNIV HosP CINCINNATI-OH

Kenjarski, Brian

Lee, Mitchell

Pr

UNIV BuFFALO GRAD MED-NY

IV BuFFALO GRAD MED-NY

FLUSHING

Maceda, Aimee
HOSPITAL MEDICAL

U MD-MERCY MED CTR

CTR-NY

Kerr, Christine

U FLORIDA PRoG-SHANDS HosP
YU SCHOOL OF MEDICINE

Mak, John

BROWN U INT MED REs- RI

Lerner, Alexander

Kim, David

ST . LuKE's-RoosEVELT-NY
WILSON MEM REG/UHS-

Y

BARNES-)EWISH HOSP-M0

B I DEACONESS MED CTR-MA
EINSTEIN/JACOBI-NY

Kozower, Rachel

Maim, Brian
METROHEALTH MED CTR-OH

Lesser, Adam
METROHEALTH MED CTR-OH

NYP HosP-NY CoRNELL-

I

WINTHROP-UNIV HosP-NY

Krakowski, David

Y

Mato, Anthony

IV Hosr-NY

HosP oF THE UNIV oF PA

Lin, Peter
MT. SINAI HOSPITAL-

Mclean, Erika

y

Lang, Christopher

Logue, Christopher

Miller, Rebecca
UN1v BuFFALO GRAD MED-NY

MT. SINAI HOSPITAL-NY
WINTHROP-U

Mepani,Jay

Morcos, Morcos
ST. FRANCIS MED CTR-PA

UNIV BuFFALO GRAD MED-NY
MAIMONIDES MED CTR- NY

RIVERSIDE METHODIST- 0H

U HLTH Svs E CAROLINA -

C

''We practice law for
your peace of mind."
Estate Planning - Personal Injury
Real Estate - Matrimonial
Elder Law

One John James Audubon Parkway
Amherst, New York 14228
716.636.7600

20

laflal1 Hysiciu

S umm e r 2 002

HOGAN &amp; WILLIG, PLLC
.\ ttorneys at Law - - - - - -

hoganandwillig.com

�Robert Gore ispleased to be going to
Cook County Hospital to train in
emergency medicine.

Mutty, Christopher

Rosella, Peter

Sorci, Jonathan

UNIV BuFFALO GRAD MED-NY

U

UNIV BUFFALO GRAD MED-NY
UNJV BUFFALO GRAD MED-

Weiss, Karen

Stanbro, Peter
MT AuBURN HosP ITAL- MA

y

Nguyen, Doan

u

LA MEDI C AL CENTER-CA

Russell, Teresa

BOSTON U MED CTR-MA

UNIV H EALTH CTR OF

Stanislawski, Aimee

BosToN U MED CTR-MA

I LLINOIS COM-CH ICAGO

Weitzman, Steven

PITTSBURGH-PA

O'Donnell, Kathleen

UNIV MAss MED ScHOOL

Samson, Gregory

LONG I SLAND ) EWISH-

Swan, Andrew
EMORY UNIV SOM-GA

UNIV NoRTH CAROLI

Oh, Richard

y

Whiteside, Michael

A HosP
H osP OF ST. RAPHAEL- CT

Schapiro, Ann

MARY I MOGENE BASSETT- NY
YALE UN I VERSITY-CT

UNIV BuFFALO GRAD MEDMAIMON I DES MED CTR-

Y

y

Osman, Magda
UN I V BuFFALO GRAD MED- NY

Ostrow, Gregory

H ARTFORD H OSP I TAL-CT

HLTH PART/REG IONs HosP-M

Symons, Andrew

Schindler, Kim

Wisnoski, Jennifer

r
UN I V BuFFALO GRAD MED- NY

UN I V BUFFALO GRAD MED-

y

UN I V BuFFALO GRAD MED- NY

Tenney, Emily

Wolpiuk, Anne

CLEVELAND CLINI C FouNDATIONOH

UN I V BuFFALO GRAD MED- NY

Schwartz, Lainie

Teper, Irene

UNIV BUFFALO GRAD MED- NY

ST . MARY's MED ICAL CTR-CA

Seereiter, Phillip

Thurlow, Juliane

UN I V BUFFALO GRAD MED-NY
UN I V B UFFALO GRAD MED-

UNIV BuFFALO GRAD MED-NY
UNIV BuFFALO GRAD MED-NY

Packianathan, Nalini
UNIV BuFFALO GRAD MED- NY

y

) OHNS HOPKINS H osP- MD

Selip, Debra

Traugott, Matthew

E1 NSTE I N/J ACOB I-NY

L ONG I SLAND )EW I S H-NY

Selkirk, Stephen

Vannelli, Patrick

Woo, Junda
BAYLOR CoLL MED- H ousTON - TX

Yoon, Daniel

YU SOM
UN I V BuFFALO GRAD MED-

Perez, Brenda

Y

ATLANTI C HEALTH SYs- N J

Shahryarinejad, Azin

Puchalski, Rebecca
BETH I SRAEL MED CTR-NY
UN I V BuFFALO GRAD MED- NY

Singh, Sandesh

Ramsdell, Robert
THOMAS ) EFFERSON UNIV - PA
UN I V BuFFALO GRAD MED- NY

lf'd

Yolfson, Alexander
CASE WESTERN RESERVE- OH

ST. }osEPH ' s-SvRACUSE-NY

y

UNIV HosP C I NC I NNAT I- OH

Pasol, Joshua
YU DowNTOWN HosP-NY

Wong, Robert
UN I V BuFFALO GRAD MED-

UN I V BUFFALO GRAD MED-

y

Siuta, Jonathan

Ridgeley, Jamison

U NEBRASKA AFFIL HosP
NYP H osP-NY CORNELL-NY

Zwerling, Brian

Walcott, Roger
NY H osP/MED CTR QuEENS
ST. ELIZABETH ' s MED CTR- MA
LONG I S LAND }EWISH MED CTR- NY

Weinstein, Jody
NAVAL HOSPITAL
PENSA C OLA-FL

PROGRAM -

U H LTH Svs E CAROL I NA- N C
UNIV BuFFALO GRAD MED-NY

u "' m e r

2 0 0 2

la ffalo Hys i c ian

21

�THE 156TH COMMENCEMENT FOR
THE SCHOOL OF MEDICINE AND
BIOMEDICAL SciENCES wAs HELD
ON

MAY

24,

2002,

AT

THE

CENTER FOR THE ARTS ON THE
NoRTH CAMPus.

THIS YEAR, THE SCHOOL CONFERRED 136 MD DEGREES, 2 MD/PHD
DEGREES,

7

MD/MBA DEGREES,

22 PHD DEGREES, 2 MPH DEGREES,
AND 27 MASTER'S DEGREES.

THE HONORED SPEAKER WAS NEW
YORK STATE HEALTH COMMISSIONER DR. ANTONIA NovELLO. CLASS
SPEAKER WAS ANTHONY

22

l1ffala Pbysicin

MATO.

��PATHWAYS

N E ws ABOUT UB' s ScHooL oF M E DICINE
AND BIOMEDICAL SCIENCES AND ITS
ALUMNI, FACULTY, STUDENTS AND STAF F
SUMMER

Skolnick t

2002

ad

Jeffrey Skolnick, PhD, a worldrenowned scientist in the fields
of computational biology and
bioinformatics, has been
named director of
the Buffalo Center
of Exce ll ence in
Bioinformatics and
UB Disting u ished
professor of structural biology at the
University at Buffalo,
the lead research
SKOLNI C K
partner in the center.
Skolnick has served as
director of computational and
"THIS C OMBI Fl
structura l genomics at the
Danforth Plant Center in St.
Sl PPORT MADE I I
Louis, Missouri, since 1999
POSSIBI E FOR US TC' and as an adjunct professor of
biochemistry at Washington
GO AFIER HIE BfSl
University in St. Louis, where
)
OF THE. BFST.
he has been a member of the
faculty since 1982. He has developed algorithms for the
prediction of protein structure
and folding pathways from
protein sequence and has pioneered the use of lattice-based
approaches to protein tertiary
structure prediction, as well as
the simulation of membranes

24

l a lfal e Phy si c iu

S t~ m m e r

20 0 2

and membrane peptides. He
has also developed structurebased approaches to predict
protein function from amino
acid sequence, protein-protein
interactions and pathways that
can be applied to entire genomes. He holds nearly
$700,000 in grant support from
various agencies, including the
National Institutes of Health.
Sko lnick earned a bachelor's degree in chemistry from
Washington University in St.
Louis and master's and doctoral degrees in chemistry from
Ya le University. He was a
postdoctoral research fellow at
Bell Laboratories from 19781979 and an Alfred P. Sloan
Foundation Research Fellow
from 1983-1987.
He is chair of the Scientific
Advisory Board on Geneformatics and a member of the
Scientific Advisory Board of
the Proteome Society and the
NIH's Molecular and Cellular
Biophysics Study Section.
Skolnick is a member of the
editorial boards of Biopolymers
and Applied Genomics and
Proteomics, and also has served

on the editorial boards of Proteins, Biophysical Journal and
Journal of Chemical Physics. He
serves as a referee for professional journals that in cl ude
Nature, International Journal
of Biological Macromolecules,
Journal of Molecular Evolution,
Journal of the American Chemical Society and Science.
Two accomplished researchers at the Danforth Plant
Science Center, Andrzej A.
Kolinski, PhD, and Marcos
R. Betancourt, PhD, will be
joining Skolnick at the Buffalo Center of Excellence in
Bioinformatics.
Kolinski is a professor at
the plant center and heads the
biopolymers laboratory at the
University of Warsaw 1n
Poland. He has won numerous
grants and earned several honors, inc! uding the Swietoslawski
Award in 1994 and an International Scholar's Award from the
Howard H ughes Medical Institute in 1995. Kolinski earned
his doctorate in chemistry from
the University of Warsaw in
1979, and has taught there and
at Washington University in St.

1
I

�1
1

Louis, in addition to having
worked at the Scripps Research
Institute in La Jolla, California.
Betancourt has worked in
the computational genomics
laboratory at the plant center.
Prior to that, he held positions
at the University of Maryland
and at the University of California at San Diego, where he
earned his doctorate in physics
in 1995. His honors include
the Enrico Fermi Award in
1986, a National Defense Science and Engineering Fellowship in 1989 and a National
Science Foundation Fellowship in 1996 and 1998.
The John R. Oishei Foundation has awarded UB a threeyear, $1,542,000 grant to help
support the salaries of Skolnick,
Kolinski and Betancourt.
"Thanks to the generosity
of the John R. Oishei Foundation, in addition to Governor
George E. Pataki's strong and
visionary financial commitment to this initiative and, at
the federal level, the efforts of
Congressman Tom Reynolds
and Senator Hillary Rodham
Clinton, we're delighted to have
secured the talents of Jeffrey
Skolnick and the world-class
team he has assembled for our
Buffalo Center of Excellence in
Bioinformatics," said President
William Greiner at the time of
the announcement. " This
combined support made it
possible for us to go after the
best of the best."

achsNamed
UB Di tinguished

Frederick Sachs, PhD, professor
of physiology and biophysics
was one of 13 University at
Buffalo faculty members named
in May2002
to the first
class of UB
Distinguished
SA c Hs
Professors.
The UB Distinguished Professor designation is open to
faculty members who have
achieved national or international prominence and a distinguished reputation within
their field through significant
contributions to the research/
scholarly literature or through
artistic performance or achievement in the fine arts.
Sachs is an authority on cell
mechanics and director ofUB's
Center for Single Molecule
Biophysics. He is also a member of the university's Center
for Advanced Molecular Biology and Immunology and its
Center for Neurobiology and
Vision. His research attempts
to understand the electrical
processes in cells. Of particular
interest are the mechanisms of
mechanoreception and the
role of ion channels.
- SU E W U ET C HER

Norton edaiConferred
on Jacobs
The late Lawrence D. Jacobs, MD, who was professor and chair
of the Department of Neurology and a wortd·renowned researcher in the treatment of multiple sclerosis IMSJ, was
chosen to receive posthumously University at Buffalo's highest award, the Chancellor Charles P. Norton Medal.
The Norton Medal is given annually at the uniYenlty's
general commencement ceremony to recocnize someone
who has, in Norton's words, "performed some great thing
which is identified with Buffalo . · . a civic or political act, a
great book, a great work of art, a
great scientific achievement, or
any other thing which, in itseH, is
truly great and enabling and
which dignifies the performer and
Buffalo in the eyes of the world."
"Larry Jacobs was one of our
most distinguished faculty mem·
ben, and a great Buffalonian-a
scholar, researcher and teacher
whose groundbreaking research
discoveries were exceeclecl only
by his compassion and his desire

to serve our university, our region
and all of humanity," said Presl·
dent William R. Greiner. "Throughout his career, Larry
brought national and international acclaim to our Depart-

ment of Neurology and the UB medical school, as well as to
Buffalo-Niagara."
Jacobs, who also held the Irvin and Rosemary Smith
Chair in Neurology at UB and served as director of the
Jacobs Neurological Institute and the William C. Baird Multiple Sclerosis Research Center at Buffalo General
Hospital, died of cancer last November at the age of 63.
His innovative research, geared toward developing better
treatment for relapsing multiple sclerosis-a form of MS
that affects 350,000 people in the United States-led to the
development of Avonex, which today is the most widely
prescribed drug to treat this debilitating form of MS.
-SUZASNE CHAMBERLAIN

- A RTH U R PA GE

Su mm e r

2002

Ia If a I a

n y sic ian

25

�PATHWAYS

Cranger Pr
nted
;t=.n ... i"F..,e Achi vemen

Carl Granger, MD, an internationally recognized authority in
the field of rehabilitation medicine and professor and chairemeritus of the Department of
Physical Medicine and Rehabilitation at the University at
Buffalo, received the Lifetime
Achievement Award at the third
Annual Health Care Heroes

Breakfast on April 18, 2002,
sponsored by Business First.
Granger was honored for
his role in developing the
Functional
Independ e n c e
Measure, or
FIM™ an
easy-to-use
rehabilitation assessGRANGER

Patrick J Kelly, MD '66, FACS, the Joseph P. Ransohoff
Professor and Chainnan of Neurosurgery at New York
University (NYU) School of Medicine, received the
Olivacrona Award from Karolinska Institute in Stockholm
in December 2001 in conjunction with the Nobel
ceremonies.
Kelly has pioneered computer-assisted stereotactic
neurosurgery and minimally invasive surgical techniques
for the removal of brain tumors-techniques he is credited with introducing to NYU Medical Center.
While a faculty member in the Department of Neurosurgery
at UB in the early 1980s-before moving to the Mayo Clinic in
1984-Kelly conducted innovative work in image.guided
neurosurgery.
To date, he has operated on more than 6,000 patients with
brain tumors and is internationally known not only as a brain
tumor surgeon but also as an expert in the surgical treatment
of movement disorders.
In April 2002, Kelly became the only neurosurgeon in
history to deliver the William P. Schneider honorary lecture at
the American Association of Neurological Surgeons (AANSJ
for a second time, having also delivered it in 1996. In this
year's lecture he talked about his experiences as a surgeon in
Vietnam in 1968-1969.
In 1997, Kelly was awarded the Scoville Achievement Award

ment tool that allows trained
personnel to assign a numerical value-the FIM rating-to
a patient's ability to function,
based on performance of 18
physical and mental tasks that
represent a basic daily routine
of personal-care activities.
The federal Centers for
Medicare and Medicaid Services (CMS), formerly called
the Health Care Financing
Administration, recently selected the FIM™ as the assessment instrument to be used by
rehabilitation hospitals to
document requests for prospective payment for rehabilitation treatment.
The FIMTM now is used by
1,400 facilities in 50 states and
the District of Columbia and
has been translated into several languages.
In conjunction with the
FIM™, Granger established
a nonprofit business, the Uniform Data System for Medical
Rehabilitation, or UDSMR, to
provide reports and store the
data for their FIM™ users. That
database now holds information on more than 4 million
patients, comprising the largest database of medical
rehabilitation treatment outcomes in the world. UDSMR
is a part of UB Foundation
Activities, Inc.
-LOIS BAKER

art-

from the World Federation of Neurological Surgical Societies,
marking only the second time in the organization's history that
this award has been given. He is also the recipient of The Sir
Peter Freyer Medal (Ireland, September 2001), and the Obrador
Medal from the Spanish Neurological Association (1996).
-S. A.

26

UNGER

luffalo Hysician

Summer

2002

Ashwani Raj put, MD, has been
appointed attending surgeon at
Roswell Park Cancer Institute
(RPCI) and assistant professor

of surgery in the University at
Buffalo School of Medicine
and Biomedical Sciences.
Rajput earned his medical degree (1993)
and completed a research fellowship in
the DepartmentofSurgery (1997)
RAJPUT
and
residency training in general surgery (2000) at Case Western
Reserve University School of
Medicine in Cleveland, Ohio.
He also completed a fellowship
in clinical oncology at RPCI
(2002). Rajput's research interests include the molecular genetics of colon cancer and other
gastrointestinal malignancies.
He is a member of the American
College of Surgeons, the Association for Academic Surgery
and Society of Surgical Oncology.
-DEBORAH PETTIBONE

nv

tors Recogniz: d

School of Medicine and Biomedical Sciences faculty named
on United States patents issued
to The Research Foundation
of the State of New York in
2001 were among those honored by the University at
Buffalo at a reception held on
May 2, 2002.
Among those recognized
were Wesley H icks Jr ., DDS,
MD '84, associate professor of
otolaryngology, who invented
the first model of a tracheal lumen that combines epithelial

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and mesenchymal elements in
a manner that mimics the tracheal lumen surface. Hicks was
also honored for his role in
developing a method for providing novel surface modified
biodegradable polyester polymers that allow small amounts
of surface modifiers to be situated on the surface. The research goal for both technologies is the development of
wound-healing membranes.
Paul }. Kostyniak, PhD,
professor of pharmacology and
toxicology; Rossman F. Giese
Jr. and Joseph A. Syracuse,
PhD, co-director of the Toxicology Research Center, were
recognized for developing an
antimicrobial composition that
can impart antimicrobial properties both in, and on, the surface of various household, industrial and medical products.
Donald D. Hickey, MD,
research assistant professor of
physiology and biophysics and
clinical assistant professor of
neurosurgery, was honored for
inventing a device and method
to provide a noninvasive
estimate of cardiac performance parameters by inserting
a catheter and balloon into the
esophagus, adjacent to the
aortic arch, to sense aortic
pressure (part of the previously
paten ted Hickey Cardiac
Monitoring System).

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CH UlOGYI&lt;.OF rH

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HI AR AARI rRLLYI tPRESSI\LA I&gt;WI APPR CIAr

Stephen Rudin, PhD, professor of radiology and codirector of Radiation Physics
Laboratory and Toshiba Stroke
Research Center, and Daniel
R. Bednarek, PhD, professor
of radiology, were recognized
for their role in developing a
radiographic image apparatus
and method for vascular interventions for acquiring veryhigh-resolution radiographic
digital images over a small
region of interest using a digital solid-state x-ray image detector for the medical imaging
application of angiography.

Faculty Who Received

e
Anthony Auerbach, PhD,
Physiology and Biophysics;
Anthony Campagnari, PhD,
Microbiology; Leonard
Epstein, PhD, Pediatrics/
Social and Preventive
Medicine; Jo Freudenheim,
PhD, Social and Preventive
Medicine; Paul Knight III,
MD, PhD, Anesthesiology/
Microbiology; Mulchand
Patel, PhD, Biochemistry;
Stanley Schwartz, MD,
Medicine; Suzanne Laychock,
PhD, Pharmacology and
Toxicology.
Inventors affiliated with the
University at Buffalo were also
recognized by the State University of New York as being

among the outstanding inventors within the SUNY system at
a ceremony held in Albany on
May 20, 2002.
The UB inventors represented more than one third of the 64
SUNY faculty and staff members from campuses across the
system who received awards for
their achievements from SUNY
Chancellor Robert L. King.
Noting this UB Provost
Elizabeth D. Capaldi says, "We
are proud that UB swept these
awards. UB's science and technology is of the highest quality
and it is a very high priority for
the university to commercialize this intellectual property.
Our faculty's achievements in
this area are truly impressive
and we appreciate SUNY's
recognition."
The SUNY inventors were
honored in four categories:
"outstanding inventor," "entrepreneur," "first-time patent"
and "first-time invention
disclosure."

Faculty members were honored
as "outstanding inventors,"
either because they have received multiple patents, their
invention has brought in considerable licensing income or
their invention is seen as
significant in other ways.
Faculty in the UB School of
Medicine and Biomedical

S umm er

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0

•

Sciences recognized in this
category were:
Claes Lundgren, MD, PhD,
professor of physiology and
director of UB's Center for
Research and Education in
Special Environments. He has
been awarded (with coinventors) more than 120 patents pertaining to, among other
areas, human engineering
(breathing gear for divers) and
the pharmaceutical fields
(Nicorette® for smoking withdrawal). Since joining the UB
faculty in 1974, Lundgren has
submitted six new technology
disclosures and has been
awarded three patents, two of
which are licensed to Sonus
Pharmaceuticals and one to a
Swiss company, Idiag AG
(equipment for respiratory
muscle training).
Timothy F. Murphy, MD,
professor of medicine and microbiology. During his distinguished career at UB, Murphy,
who conducts research in the
area of vaccine development,
has submitted 11 disclosures.
Nineteen U.S. and foreign patents have been issued and many
more are pending. He is working on a vaccine that targets a
bacteria that is the second most
common cause ofear infections
in children and a leading cause
of recurrent infection in patients with chronic obstructive
pulmonary disease.

2002

laffale Pbysiciu

27

�PATHWAYS

Frederick Sachs, PhD, UB
Distinguished Professor of
Physiology and Biophysics.
Sachs has submitted more than
35 invention disclosures.
In a recent study published
in Nature, he reported that a
protein isolated from the
venom of a Chilean tarantula
shows promise as a drug to
prevent and treat atrial fibrillation, a chaotic beating of
the heart that affects 25 million
Americans. Several companies
are considering the technology
for licensing.

Those honored as "entrepreneurs" have demonstrated
entrepreneurial spirit that
enabled them to move their inventions from the research
laboratory into wide-scale use.
Faculty in the UB School of
Medicine and Biomedical
Sciences recognized in this
category were:
EdmundA. Egan, MD, professor of pediatrics and physiology, and Bruce A. Holm,
PhD, senior vice provost and
professor of pediatrics, pharmacology and toxicology, and

gynecology-obstetrics. Egan
and Holm developed the commercial surfactant-replacement
therapy, INFASURF neonatal,
which received new drug approval from the Food and Drug
Administration in 1997 as a lifesaving drug that has been
demonstrated to reduce the
morbidity and mortality of
premature newborn infants.
INFASURF adult is now in
phase II clinical trials.
INFASURF drugs are manufactured by ONY, Inc., located in
the UB Technology Incubator,
part of the university's Office

of Science, Technology Transfer and Economic Outreach.

Faculty in the UB School of
Medicine and Biomedical Sciences recognized for receiving
their first patents in 2001 were:
Wesley L. Hicks Jr., DDS, MD,
associate professor of otolaryngology and attending head and
neck surgeon at Roswell Park
Cancer Institute, and Frederick
Sachs, PhD, UB Distinguished
Professor of Physiology and
Biophysics.
4D
- LORRAINE WAPPMAN
AND SUE WUETCHER

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laffal1 Physician

S umm e r

2 00 2

705 Renaissance Drive
Williamsville, New York 14221

�and physiological feedback systems led to the publication of
two books on the subject.
Dougtas S. Riggs, fonner chair of the Department of Phann·

Riggs and his wife of 60 years, Robin Palmer Riggs,

acology in University at Buffalo's School of Medicine and

shared an uncompromising belief in pacifism. With her help

Biomedical Sciences, died on December 22, 2001, at his

Riggs was a conscientious objector in World War 11, took in

home in Halifax, Canada. He was 87.

Hungarian refugees after the 1956 revolution and worked

Born in Harpoot, Turkey, of missionary parents, Riggs
was educated at Rollins College and at Yale University, where
he earned BS and MD degrees. Prior to coming to UB as chair

of the Department of Pharmacology in 1954, he pursued an

with Physicians for Social Responsibility in the Nuclear
Freeze Movement.
Riggs is survived by his three children: Timothy A.
Riggs of Durham, NC, Virginia P. Riggs, MD (Wendy Lyons)

academic career in pharmacology, with teaching positions at

of Suffield, CT, and Robin Elizabeth Sagurna of Taufkirchen,

Yale and Harvard universities.

Gennany; three grandchildren; and a brother, Lorrin A.

Riggs was a respected researcher, a gifted teacher and

Riggs of Hanover, NH.

an enthusiastic mentor. His fascination with mathematics

Keyser Cadillac

History of Orthopaedic
surgery at UB
Eugene R. Mindell, MD, chair of the Department of Orthopaedic
Surgery at the University at Buffalo School of Medicine
and Biomedical Science from 1964 to 1988, has
written a history of the department, which is now
available for purchase. The book includes an over·
view of trends in orthpaedics, both locally and
nationally, that impacted on the development of
this department, starting in about 1860 and
continuing to the present. Complementing this
overview are infonnative descriptions of universityhospital affiliations dating from 1848 to the present,
and succinct profiles of faculty who contributed to ortho·
paedic education at UB over the last 155 years. Also chronicled is

Upstate New York's only
exclusive Cadillac Dealer

the evolution of medical student curriculum and residency training
in orthopaedic surgery in Buffalo. Supplementing the 70-page text
are 80 photographs, spanning the entire history of the department.
The book, titled History of Orlhopaedic Surgery at the University
at Buffalo, can be purchased for $25 by sending a check, made

payable to the University at Buffalo Foundation, to Michael Quinn,

Keyser Cadillac

Orthopaedic Surgery Department, University at Buffalo, Hayes

4130Sheridan Drive· Williamsville. Y

Annex A, 3435 Main Street, Buffalo, NY 14214. All copies of the

634-4100
key ercadillac.com

book and sale proceeds have been donated to UB's School of
Medicine and Biomedical Sciences by Dr. Mindell.

Summer

2002

4D

luffalo Pbysician

29

�BY

S.

A. UNGER

PRESIDENTIAL AssASSINATIONS,

Up

osean

I

e c

-REEXAMINING THE DEATHS OF KENNEDY AND McKINLEY

chair of the Department of Legal Medicine Trauma, presented a talk titled "Trauma Care
at Virginia Commonwealth University, Today." He described treatment McKinley
Medical College of Virginia, and codirector received in 1901 after he had been shot in
of the Virginia Institute of Forensic Science Buffalo and then contrasted this with the
and Medicine. Fierro presented a fascinating care a president similarly wounded today
look at both the Kennedy and McKinley au- would receive; he also outlined the detailed
topsy reports from the perspective of a for- medical-contingency and security plans that
ensic pathologist with decades of experience would be put in place wherever the chief
executive travels worldwide.
studying fatal gunshot wounds of all kinds.
After a brief break, the Stockton Kimball
In
keeping
with
the
lively
public
debate
he University at Buffalo School of
Lecture
was delivered by Jack C. Fisher, MD,
surrounding
Kennedy's
assassination
over
Medicine and Biomedical Sciences'
emeritus
professor of surgery and former
the
decades,
Fierro
peppered
her
talk
with
65th Annual Spring Clinical Day was
head
of
the
Division of Plastic Surgery at the
candid
and
thought-provoking
rebuttals
of
held on April 27,2002, at the Buffalo/
of
California at San Diego. Fisher,
University
a
number
of
conclusions
reached
by
Becker.
Niagara Marriott. The program, sponsored
who
has
authored
a book on the McKinley
Following
Fierro,
Roger
Seibel,
MD
'66,
by UB's Medical Alumni Association, focused on "Presidential Assassinations in the UB clinical professor of surgery and ortho- assassination titled Stolen Glory, recounted
20th Century."
The opening talk was titled "A Surgeon

pedics and medical director of the Regional
Evaluation for Quality Improvement in

how he had become interested in this subject
while a medical student at UB. He then pre-

Looks at the Assassination of John F.
Kennedy" and was delivered by Donald R.
Becker, MD, a UB emeritus clinical professor of surgery. Becker provided a riveting
description of Kennedy's assassination-his
wounds, emergency room treatment and
autopsy (the latter of which he characterized
as "chaotic"). He also reviewed the criminal
investigation that followed, the findings of
the Warren Commission and the myriad
conspiracy theories that persist to this day.
Becker was followed by Marcella Fierro,
MD '66, chief medical examiner for the
Commonwealth of Virginia, professor and

30

luffall nysician

S ummer

2 002

I

�sented a well-argued case for why the con-

Sullivan, Sharon Murphy, Teresa Vietti and

troversy surrounding McKinley's operative

the late Brigid Leventhal. His prominence on

and postoperative care in Buffalo should
finally be laid to rest.
At the close of the lectures, the audience

the Hodgkin's and non-Hodgkin's lymphoma
disease committees of the Pediatric Oncology
Group, as well as his role as principal investi-

had an opportunity to ask questions of a

gator of seminal phase 3 studies of children

editor in chief of Vaccine Bulletin. He also
serves as a reviewer and editorial board
member for many other publications, including Pediatrics.

panel made up of the morning's speakers,

with these disorders, have Jed to important ad-

After leaving Buffalo in 1974, Dantzker

after which attendees gathered for a lun-

vances in treatment worldwide. In addition to

cheon, where Fisher was presented with
the Stockton Kimball award by Stephen

his scientific and academic credentials,
Brecher is known as a devoted, tireless and

Pollack, MD '82, on behalf of the UB

compassionate pediatrician who exemplifies

served as an instructor in the Department of
Internal Medicine
at the University of
California at San

Medical Alumni Association.

the best qualities of a caring physician.

Diego for a year
before joining the

Each year at Spring Clinical Day, medical

of pediatrics at the UniversityofCalifornia at

faculty at the Universityof Michigan,
where he contrib-

alumni achievement awards are presented to

Los Angeles and director of pediatric infec-

uted greatly to the

graduates of UB's School of Medicine and

tious diseases and the Pediatric AIDS

growth and reputa-

Biomedical Sciences. Recipients are nominat-

Program at the Cedars-Sinai Medical Center

tion of the Depart-

ed by their fellow alumni, with final selections made by the governing board of the

in Los Angeles. Prior to that, he served for six
years as professor and head of the Division

ment of Internal
Medicine's Pulmo-

Medical Alumni Association. This year's re-

of Infectious Diseases in the Department of

nary Medicine Sec-

Pediatrics at the University of Texas Health

tion. In 1983, he moved to the University of

Science Center at San Antonio, where from

Texas Health Science Center in Houston,

1975 to 1981 he was professor and chair of

where he served as professor and vice chair
of the Department of Internal Medicine

atrics at Roswell Park Cancer Institute, chief

the Department of Pediatrics. Brunell was a
member of the Advisory Committee on Im-

of the Division of Pediatric Hematology/

munization Practices

Oncology at Kaleida Health's Children's

of the Centers for Dis-

cine. In 1990, he was nam-

Hospital of Buffalo and chief of pediatric

ease Control (CDC)

ed chair of the Depart-

hematology/oncology in the Department of
Pediatrics in the University at Buffalo's

and the Consultative
Group on Vaccine De-

ment of Medicine at Long

School of Medicine

velopment, which is

and Biomedical Sci-

concerned mainly with

medicine at Albert Ein-

ences. He is recog-

evaluating vaccines for

stein College of Medicine

nized as a national

developing countries.

in New York City. He is

He has also served as a
member and chair of

currently a partner in a

of childhood lym-

the Committee on In-

Wheatley Medtech Part-

phomas and has

fectious Diseases of the

MEDICAL ALUMNI
Since 1987, Brunell has served as a professor

cipients are as follows:

Brecher is chair of the Department ofPediat-

and international
authority in the area

and Critical Care Medi-

Island Jewish Medical
Center and professor of

biotechnology company,
ners LP. Dantzker has

Academy of Pediatrics
(the Red Book Committee). In addition to

disease and non-

serving as a consultant to the World Health
Organization, the CDC, the National Insti-

textbook Cardiopulmonary Critical Care,

Hodgkin's

lym -

tutes of Health and the Food and Drug Ad-

which is the foremost text of its kind. He

phoma in children

ministration, Brunell has contributed to most
of the standard textbooks of pediatrics, med-

also established a major investigative jour-

icine and infectious diseases in the area of his

served on the editorial boards of numerous

expertise. Currently, he is chief medical
editor of Infectious Diseases in Children and

other journals, including The American
Review ofRespiratory Diseases.

published more than
stracts on Hodgkin's

and adolescents.
Brecher is first author on many papers,
published in collaboration with such prominent pediatric oncologists as Margaret

:~
0

and director of the Division of Pulmonary

authored more than 100
peer-reviewed papers and several text-

400 articles and ab-

c

a
E

books. He is best known for his remarkable

nal, The Journal of Critical Care, and has

S Limm e r

2002

luffale Physician

31

�A

L

U

M

N

Spring Clinical Day

B rkson M morial Award
The RobertS. Berkson, MD, Memorial Award in the Art ofMedicine
is presented annually to honor the values and ideals epitomized by
Dr. Berkson, who was an esteemed family physician in Buffalo.
Patient care was his forte; competence, compassion, patience and
dedication to teaching were his
virtues. His special expertise in
"the art of medicine" is perpetuated in this award.
This year, the award was
presented to Lawrence Golden,

Lawrence Golden

a local cardiologist who has
served in a number of leadership positions at Millard
Fillmore Hospital, including
chair of the Department of
Medicine (1969-86), chief of
cardiology (1967-87) and director of the Cardiology Fellowship Program (1980-92).

Throughout his career, Golden has given freely of his time and
expertise to a wide variety of services and programs, according to
Margaret Paroski, MD, senior associate dean in the School of Medicine and Biomedical Sciences, who nominated him for this award.
"In addition to dedicating his life to giving his patients the best
care possible and teaching the students and residents how to appreciate the humanism of medicine, Dr. Golden and his wife, Nancy,
recently endowed a lectureship series in mind-body medicine at our
school," says Paroski. "This generous gift builds upon what his
many years of voluntary service have exemplified to our studentsthat physicians who are well versed in mind-body medicine concepts will better provide humanistic care for their patients."

D an's Community Service Award
Melvin Oyster is the inaugural recipient of the Dean's Community
Service award, which recognizes outstanding accomplishments that
contribute to making our community a better place to live.
"After 50 years in medicine, I can recall only five outstanding
physicians, and Dr. Mel Oyster is one of them," says Francis Fote,
MD '52, who introduced Oyster
at Spring Clinical Day.
Oyster is best known for
having established the accred-

Gentzke &amp;
Associates, Inc.
Registered Investment Advisor

ited Family Practice Residency
Program in Niagara Falls, New
York, which has graduated 90
residents since 1974. The program grew out of an internship
he created in 1952 that was
dedicated to preparing students
for family practice.
"He did this without having

Private Portfolio
Management

President and CEO Glenn Gentzke

and Ch1ef Investment Strateg1st
Chns King

Tax Consulting

was one of the first to participate in the internship. "And he earned
recognition for the program the hard way. Initially his request for help
to support it was turned down by UB's medical school, so he looked

Estate Planning

instead to the University of Rochester School of Medicine."

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Management

UB Commons
520 Lee Entrance

TIAA -CREF Advisor

Suite 205

Network

Amherst, NY 14228

Tel: (716) 639-0475

had any formal residency training himself," recalled Fote, who

Certified QuickBooks
Professjonal Advisors

www.gentzke.com

In addition to founding the residency program, Oyster continues
to be "medical director of everything in Niagara Falls that concerns
the poor and underprivileged," according to Fote. "He continues to
work and teach with the enthusiasm of his youth, long after his contemporaries have retired, and he remains a favorite of the students."
Thomas Rosenthal, MD '75, chair ofUB's Department of Family
Medicine, says, "Dr. Oyster has been a mentor to me since I was in
medical school, and he continues to offer insight into how I, as
department chair, can best serve primary care physicians in Western
New York. He is an outstanding physician, a leader with energy, an
innovator with style, and an educator by example. Dr. Oyster defines community-based primary care."

32

luftal• Hysiciaa

Summer

2002

4D

�was elected president of

· will se"e as treasurer. Kozera is

the Medical Alumni Association on April27, 2002, at Spring Clin-

the medical director for social services and assistant medical

ical Day. Duffner is a UB professor of neurology and pediatrics and

administrator for Erie County Health Department.

a physician in the Department of Neurology at Kaleida Health's
Children's Hospital of Buffalo.

will se"e as the new vice
president for the association. Pollack is a UB clinical assistant professor of ophthalmology who is in private practice in Williamsville.

GENESEE
HEARING SERVICES
61 Wehrle Drive
(Near Harlem)
Amherst 14225

THE AUDIOLOGY

CENTER
630 Orchard Park Rd.
(Near Ridge Rd.)
West Seneca 14224

712-2000

837-6213

• Diagnostic audiometric evaluations (pediatric and adult)
• Digital &amp; programmable hearing aid fittings on 60-day trial basis • Tinnitus evaluation and therapy
• Vestibular evaluation for patients with dizziness/vertigo • Vestibular therapy • State of the art facilities

"The Ear is the Road
to the Heart" rvouaireJ

Jerri Kaplan Joyce, MA

Summ e r

2 00 2

Buffalo Physicin

33

�DEVELOPMENT

N

E

w s

The Choice to leave ale ac
By Li nda J . Cor de r , PhD. CFRE

of my first child and became a member of the "older
generation" quite recently, when my last parent, my
mom, died. Neither transition was unexpected. We are
schooled in this normal course of events from our
earliest years. It is, however, our personal experience of
these transitions that gives the concept, "Generation to
Generation," substance.
On this day of transition, we met, a small group of
those closest to my mom, with several doctors and a
hospital social worker. The lead doctor explained what
had happened medically, since Mom's admission several days before. One or two others added some small
detail. Altogether, we spent forty minutes discussing the physical aspects of
her body's rapid deterioration, in both
technical-and very down-to-earthterms. Each ofher children reaffirmed
what we had accepted in our hearts the
night before around her bed: If there
was no hope, life support should be
withdrawn.
At the end of this discussion, one of Mom's ministers-a woman not many years younger than ! suggested we say the Twenty-third Psalm together, "one
of Eva's favorites." Hand spontaneously joined hand
around the circle, physicians and children, grandchildren and close friends. Familiar words both comforted
and strengthened each of us for our respective roles in
the final few minutes of her long, loving life, already
irrevocably complete.
I was participant and spectator at once.
I was grateful for the education and experience of
these doctors, that they handled this particular endof-life discussion with such compassion and caring.
(I hoped that it was typical.) I was thankful that they
were part of the circle that symbolized our contemplation of the mystery of life, and what it meant to walk
in the shadow of death.

34

Ia f fa II P b J sic i a1

Summer

2002

This healing and profound transitiOn also made
me proud to be a part of one of our nation's medical
schools. It made me want to return home and make certain that UB's curriculum included practice in these
crucial conversations. It made "The Oath," repeated by
each new class of graduating
medical doctors, more poignant
and imminently real: " ... I will
"It made crystal clear
tread with care in matters of life
that medicine is art as
and death. If it be merely within
my abilities to help ease suffering
well as science, and that
at the end of a life, may I face this
we must provide our
awesome responsibility with humility and awareness of my
students with experi·
own frailty." It made crystal clear
ences along this entire
that medicine is art as well as scicontinuum."
ence, and that we must provide
our students with experiences
along this entire continuum.
My sibs and I spent the rest of that day of transition
making arrangements. Mom's service was a celebration, and memorials were designated for nonprofits in
which she was involved for many years.
Who can say where her impact will be the greatest?
For those who knew my mom, memories, love,
values, hope, even her genes, are her most direct
legacy. For others, it will be the story of her courage to
change and grow, her ideals and career as a teacher. It
may also be the scholarship created in her memory
that will provide an opportunity for a few more members of the next generation to earn a college degree.
When it comes right down to it, such possibilities are
why I work in this field, for UB and wholeheartedly
through our current campaign-to assist those who,
like my mom, choose to leave a legacy that will truly
make a difference from "Generation to Generation."
Linda (Lyn) Corder, PhD, is associate dean for alumni
affairs and development. She can be contacted at 1-877826-3246, or via e-mail at ljcorder@buffalo.edu. CD

�SUMMER

2002 1 - - - - - - - -l

FI RST ROW, LEFT TO RIGHT' GUEST MARGARET PAROSKI (SENIOR ASSOCIATE
DEAN), DANIEL CuRTIN.jOHN SHEFFER. HENRY GARDNER. SECON D ROW:
WILLIAM EDGECOMB, PHILIP REITZ, DONALD C. NUWER, ROBERT jAEGER,
ANTHONY PREZYNA. HANS

f.

KIPPING,jAMES STAGG, jAMES PHILLIPS.

Summer

2002

l 1ffale Hysiein

35

�,
FIRST Row, LEFT TO RIGHT· DONALD H. SPRECKER, 0LIVERj. STEINER, RALPH 0BLER, BERNIE DAVIS, EUGENE
W. LOESERjR., ROBERT McDONOUGH WILSON, KURT j. WEGNER, AARON SIMPSON, PHOEBE E. SATUREN, jOSEPH
f. CENEWICH, FRANCIS A. FOTE, DONALD F. DOHN, MILTON C. lAPP, ROBERTA. BAUMLER, MELVIN B. DYSTER,
jOHN Y. RANCHOFF,jAMES F. ZELLER, DONALDj. KELLY, MELVIN KROHN, NEAL fUHR.

,
FIRST ROW, LEFT TO RIGHT· BEN CELNIKER, CERMANTE

L.

BONCALDO, ROBERT B. SuSSMAN, SHERMAN

WOLD MAN, jAMES E. lASRY, j. DAVID SCHNATZ. SECOND ROW: fRANKj. CHAFEL, SOL MESSINGER , PHILIP ALFRED
BRUNELL, BERNARD WAKEFIELD, jOHN PARKER, ARTHUR L. BECK, PAULL. ARCHAMBEAU.

36

llffall nysiciaa

�FIRST Row, LEFT TO RIGHT: DAVID
CARLSON, ALAN POHL, GEORGE R.
TZETZO. SECOND ROW: RONALD

I.

DOZORETZ, PHILIP D. MOREY,
ROBERTA. KLOCKE, jACK C.
fiSHER, PAULj. LOREE, ANTHONY

P.

MARKELLO, M I CHAEL M .

MADDEN, MELVIN j. STEINHART,
SEBASTIAN S. fASANELLO.

FIRST Row, LEFT TO RIGHT•
ROBERT

M.

BENSON,jOHN

RANDALL ANDERSON, RONALD P .
jOSEPHSON, DAV I D R. DANTZKER.

SECOND Row: jACOB KRITEMAN.
T H OMAS P. O'CONNOR, ARTHUR
C. SOSIS. GoiNG UP STAIRS ON

THE LEFT, BOTTOM TO TOP· jAMES
P. GIAMBRONE, THOMAS P.
SHEEHAN, RICHARD G.
jUDELSOHN, ANTHONY LO GALBO .
LAST FOUR BOTTOM TO TOP:

T H OMASAUGUSTI NEjR.,j. BRIAN
SHEEDY, DONALD

E.

MILLER,

Rocco C. VENUTO.

Summer

2002

1111111 Phys ici n

37

�SUMMER

FIRST

Row,

2002 1 - - - - - - - - '

LEFT

TO RIGHT: ROBERT
EINHORN, LINDA
A. KAM. SECOND

Row:

RICHARD

SAVAGE, MARTIN
BRECHER.

I

FIRST ROW, LEFT TO RIGHT: EuGENE A. PAUL, HOWARD LIPPES, IRA l. SALOM, LINDA SMITH, ALAN S. KURITZKY,
RONALD A. VIDAL, CARLj. SCHMITT. SECOND ROW: MARK DE~ARIE,jOSEPH K. BYLEBYL, 0URET S. SMITH,
KEVIN C. GREENIDGE, GREG YOUNG.

38

l1ffale Pkysiciae

Summer

2002

�FIR.ST ROW, LEFT TO RfGHT: GERALD A. HARSTER, I VAN A. B AUMWELL, NA!'&lt;CY j. PETERS, jESS ICA R OCKWELL,
SUSAI'&lt; fiSCHBECK, MARY A. KELLY, ELIZABETH P. BARLOC. SECOND ROW:

TI~!OTHY j. CEERING,jO H N

S.

SANTELLI, ARLENE R. CURRY, DOUGLAS K . PLESKOW, RAND! C. PLESKOW. LINDA C. RABINOWITZ. ROBERT A.
CIANFAGNA, jOSEPH P. LEBERER. THIR.D ROW: ANDREW R. HORDES. jOSEPH f. GIOIA, DAVID

I.

KURSS, jOSEPH

WAYNE, RICHARD HEATH, STEPHEN POLLACK PATRICK HURLEY, 1\EIL KLUGER, KEV I N BARLOG, PHILLIP
STEGEMAN, ROBERT STERN, jOSEPH CELORMINI.

BOTTOM TO TOP: ADA\! K. ASHTON, TIMOTHY BUKOWSKI, DANIELA. BUR!'iS, PATRICKj. SHAUGHNESSY, YUOKO
YERACARIS, CARLOS LOPEZ, CAETANO SCUDERI, KATHY LiLLIS. PATRICIA

L. KAUFMANN, DOLORES C. LEONARD

]. KEVIN QUINLIVAN. IVAN HARANGOZO, MICHAEL B. WEINBERG. MICHAELS. WATSON.

S11mmer

'

2002

llfflll nys i cial

39

�Flli.STROW, LEFT TO RIGHT: jOHN K. CUMMING, KATHARYNE SULLIVAN, DIANE SANFILIPPO,jUDINE C . DAVIS, SHERI
BACZKOWSKI

ILDIKO MIKOS, PATRICIA A. VORIES, MAUREEN E. DLUGOZIMA, SHARON R. MALLEN, PHILOMENA~. BEHAR,

REBECCA HAVERLY, GAYLE FRAZZETTA, ROBERT HAVERLY, KEVIN
jACOBSON, MARK IPPOLITO, BRIAN

E.

J. McGRATH. SECOND ROW:

BOB l.AUDICO, MARK

PIOTROWSKI, MICHAELA. COLUCCI, GERARD DILLON, EILEEN CRESPO , CYNTHIA

JENSON, EvELYN CoGGINS, SUZANNE ROSENBERG, STEPHANIE fRETZ, CATHY YI, VINEET SINGH.

FIRST ROW, LEFT TO RIGHT• jEANNIE KAO - KOENIG, SUCHITRA KONERU,jANICE M. LEE, CLAUDIAjARAMILLO LEE, ANDREA
TORSONE. SECOND ROW: DAVID NOVAK, WILLIAM WIND, BENJAMIN KOENIG, fRANK M . LEE, RONIKA D. CHOUDHARY,
CATHERINE COSTELLO. jARED C. BARLOW JR., PETER ERCOLINO . THIRD ROW: CHARLES SEVERIN, RAVI K. DESAI, M. ANGELA
MCLELLAN,jOSEPH

40

11ffal1 Hysiciu

L.

CHOW, THOMAS R . ELMERjR., ALEXANDER MARCUS.

Summer

2002

�Dear Fellow Alumni

'

tis with great pleasure that I begin my year as president of the Medical Alumni Association (MAA ).
John Bodkin, who served as president for the last two years, ran the organization smoothly and
successfully, with insight, intelligence and good humor. I am pleased to announce that he has promised to continue to play an active role as past president.
This year's Spring Clinical Day-a fascinating blend of medicine and history-was
extremely successful, and I invite you to read about it, starting on page 30 of this issue.
Over the past several months, 1 have had the opportunity to serve as a member of the
Liaison Committee on Medical Education (LCME) Task Force, a self-study group that
reviews all aspects of the medical school in preparation for the accreditation review in
October. The last LCME visit was in 1994, and since then there have been a number of
significant developments at our school. For example, lecture halls have been renovated
and new classrooms and seminar rooms added-all of which are equipped with the latest
educational technologies. A new curriculum has been developed for the first- and secondyear students that combines basic science and clinical teaching, with less emphasis on lectures and
more on small-group and independent learning.
Since 1994, recruitment in the basic sciences has been very successful, and faculty in these areas
(including those at Roswell Park Cancer Institute and Hauptman-Woodward Medical Research
Institute) have received grants equivalent to the 86th percentile of all medical schools in the country.
The clinical faculty has also seen a sizeable increase in research dollars.
Under Dr. Bernardino's leadership, an infrastructure for the medical school has been put in
place, with clear-cut lines of authority. Direct communication between the medical school
administration and faculty has been greatly enhanced by Town Hall meetings that are hosted by
Dean Bernardino at each of the clinical sites.
As is the case elsewhere in the country, the biggest challenge to medical education in Buffalo is
the shortage of hospitalized inpatients for third- and fourth-year medical students. Additional
outpatient teaching clinics in hospitals and private offices will be necessary in order to train medical students and residents in the future. As such, the school's administration and faculty are
working hard to establish and enhance these venues throughout our community.
Finally, following the tragedy of September II, the enormous financial pressures on New York
State have directly impacted the medical school. Because our endowment is so limited, money for
scholarships, minority student recruitment and funding of resident and medical student research
projects is suboptimal. I hope that the medical alumni will take up the challenge to increase donations to the medical school to support these important projects. Medical students are our future and
we need to do everything we can to get the brightest and most compassionate to come to Buffalo.
In closing, I would like to say that it is a great honor to serve as president of the MAA. If you have
concerns or questions that you feel I can address on behalf of the association, please feel free to
contact me at any time by calling the MAA office at (7 16) 829-2778.

I /_LA-

PATRICIA K. DUFFNER, MD •72
President, Medical Alumni Association

Summer

2002

luflalo Physiciaa

4 1

�C

L

A

1950s
John W. Richards, MD '52,
FACS, writes: "I retired

from general surgery in
Chicago 1992 and like
living in the Ft. Lauderdale area very much.
Enjoy opera, symphony
and ballet here, plus
great weather. "

N

0

T

E

S

the antique car hobby.
We spend our summer
months in Western New
York, at our 150-year-old
home in Franklinville,
NY, and keep up contact
with our Meyer Eye
Department colleagues."
E-mail address is:
thelorees@hotmail.com.
William Sperling, MD '66,

Jacob (Jack) Lemann Jr.,
MD '54, New Orleans, LA.

E-mail address is
dr.jack@lemann.net.

"In May 2001, I retired
from Kaiser Permanente,
where I practiced pulmonary and critical care

with one office in suburban Williamsville, NY,
and the other in midtown, Buffalo, close to
the Children's Hospital
of Buffalo and the school
of medicine. The city office, especially, serves a
highly diverse and often
clinically challenging
population of children
and adolescents.
Because of my interest
in public health and epidemiology, I serve as the
medical director of the

spending two exciting
years traveling nationwide and internationally.
I have been a member
of the New York State
Immunization Advisory
Council since its formation by the governor and
legislature in I 995.
With the rapidly
expanding spectrum of
vaccines that have been
introduced in recent
years, I have had a busy
schedule teaching and
consulting on the subject."

care physician with
Group Health Cooperative in Spokane, W A. The
sun and snow were great,
and it is hoped that there
will be more trips in the
future." E-mail address:
schaffer@icehouse.net.
Robert Z. Fialkow, MD '72,

writes: "My wife, Mikie,
and I live in beautiful
Owensboro, Kentucky,
where we are building a
farmhouse on our 22acre farm. We have three

Michael S. Bardo, MD '55,

writes: "I retired from
medical practice on December 31, 2001, because
of my wife's illness. My
last 11 years of medical
practice were with the
State of California at the
California Correctional
Center, where I served as
the chief medical officer."

1960s
Jack Fisher, MD '62, writes:

"In June 2002-at the
tender age of 64-I
graduated with a master
of arts degree in history
from the University of
California at San Diego
as a member of the class
of '02-40 years after
'62!" E-mail address is:
jfishermd@aol.com.

medicine. My wife, Barbara, and I are traveling
around the U.S. and
Canada in our motorhome. We are also enjoying tandem bicycling and
playing golf and tennis. "
E-mail address is:
billsperl@aol.com.
James Giambrone, MD '67,

is director of the Catholic
Health System, Western
New York Board of Directors; also chief operating officer for Associated
Physicians ofWNY, P.C.
Richard Judelsohn, MD '67,

writes: "Sally and I are
Florida residents (Ft.
Lauderdale) and are enjoying retirement, traveling, grandchildren, and

writes: "As a practicing
pediatrician for over 25
years, I am the managing
partner of Buffalo Pediatric Associates. The group
has six physicians and
two nurse practitioners,

luffalo Hysiciaa

S umm e r

Paul J. Loree, MD '62,

42

assnotes

200 2

Erie Country Department of Health. My responsibilities there cover
a broad range, including
supervision of programs
for school health, chi!dren with special needs,
inner-city clinics, STD
and TB clinics, outbreak
investigation and control
and immunizations.
Vaccine-preventable
diseases-and their
eradication-have been
of special interest to me
since my pediatric training at Cornell Medical
Center-New York Hospital (where I volunteered
at city vaccination dinics ), followed by appointment to the Epidemic
Intelligence Service at the
Centers for Disease Control. At the latter, I was
an immunization officer,

E-mail address is:
judelson@bflo.co.erie.ny.us.

Donald P. Copley, MD '7D, a

cardiologist with Buffalo
Medical Group, P.C.,
was installed as
the new
president
of the
Medical
Society of
the County of Erie on
May 7, 2002.
Daniel J. Schaffer, MD '7D,
and Alan Podosek, MD '7D,

reunited this past january
in Vail, CO, for a week of
skiing. Alan has a private
practice in Lynchburg,
VA, and Dan is an urgent

sons: Dr. Lawrence
Fialkow, who lives in
Charlottesville, VA;
jared, who graduated
from medical school in
Philadelphia in May and
who presented us with
our first grandchild in
January 2002; and Ethan,
who is married to a gorgeous Japanese girl and
is a first-year law student
at the University of
Louisville.
I run four dialysis
units with my two associates and contemplate retirement in the next few
years to enjoy my hobbies of running, tennis,
music and video poker. "
E-mail address is
fialkow@yahoo.com .

��CLASS

NOTE

Bruce R. Javors, MD '73,

received the Award of Merit from the Rochester Academy of Medicine in 2001. A boardcertified surgeon who practices at Rochester
General Hospital, as well as a fellow of the
American College of Surgeons, Dynski holds
numerous faculty positions and finds time to
teach surgical, internal medicine and 08-GYN
residents. She is also the liaison between the

writes: "I was recently
named chairman of radiology at St. Vincent's
Catholic Medical Center
in NY. I was elected to
become a Fellow of the
American College of
Radiology, effective this
September. Last year, I
was appointed professor
of clinical radiology at
New York Medical College. I have just completed the manuscript
for my second text, to be
published this fall by
Springer-Verlag. My
wife, Susan, and daughter, Alii, continue to light
up my life." E-mail
address is: bjavors@
saintvincentsnyc.org.

Department of 08-GYN and has served as
director of the Breast Clinic at the Women's

John Marra, MD '74, is a

Center since 1992.

cardiologist at Good
Samaritan Hospital in
Baltimore, MD. He is
director of cardiac rehabilitation and assistant
professor of medicine at
johns Hopkins University. He and his wife,
Maggie, live in Roland
Park and have three
children.

Dynski, who is a sister of St. Joseph, is involved in numerous community programs and
has been a Special Olympics volunteer since
1997. She is a member of a Congregational
Committee to evaluate the future of geriatric
needs and member of a committee on medical
ethics advising the Catholic Diocese of Rochester through the Department of Social Justice
and Social Ministries.
"Perhaps most admirable and intriguing
about Marge," writes her friend Jeanne Grove,

DO, "is her courage and continuing accomplishments in spite of being paralyzed from
the waist down" as a result of complicated
back surgery in 1994. "Through intense rehabilitation and amazing perseverance, Marge
has taught herself to walk without gaining
sensation in her lower body.
"A quote by Willa Cather, I feel, epitomizes
Dr. Marguerite Dynski as follows: 'There are
some things you learn best in calm and some
in a storm."'

Larry Altschul, MD '77,

writes: "I can't believe it
has been 25 years already.
My wife, Mercedes, and I
live in Dix Hills on Long
Island. I am the 'senior'
(I can't believe that word
actually applies to me)
partner in a large cardiology practice. Since April
2000, I have been director of cardiology at Good
Samaritan Hospital

44

llffala nysicin

Summer

2002

Medical Center. We have
five children, ages 15, 17,
19, 21, and 22." E-mail
address is: drlarryalt@
aol.com.

Andrew S. Ross, MD 'BD,

writes: "I have been in
practice in Boca Raton,
FL, since 1986. I completed my general surgical residency and colon
and rectal surgical fellowship. I practice in the
largest surgical group in
South Florida ( 11 surgeons). I have a busy
colorectal practice with a
lot of laparoscopy. I
remain happily married
(26 years) and have three
wonderful daughters:
Dara, age 23, llana, age
\9 and Jordana, 16."
E-mail address is
arossl7481@aol.com.
Adolph Soto Jr. MD '83,

writes: "! am still working for Saint Vincent's
CMC of New York as a
pyschiatrist-Harrison,
NY. Adopted a baby,
Lucas Enrique, born on
january 18, 2001." E-mail
address is asoto@
saintvincents.com.
Herbert B. Newton, MD 'B4,

writes: "My family continues to enjoy Columbus and Ohio State. Alex
is into TaeKwonDo,
swimming, soccer and
riding his bike. Ashley is
into ballet, gymnastics,
swimming and piano lessons. Cheryl is still the

clinical nurse specialist
for the neurology/neurosurgery floor at OSU.
Work remains busy as I
continue my role as the
director of neurooncology at OSU and the
james Cancer Hospital. I
was recently elected vice
chairman and chairman
elect of the NeuroOncology Section of the
American Academy of
Neurology. In addition,
I am thrilled with the
publication of an article
entitled "Review of the
Molecular Genetics and
Chemotherapeutic Treatment of Adult and Pediatric Medulloblastoma"
in the December 2001
issue of Expert Opinion
on Investigational Drugs.
Blackford Middleton, MD

'85, writes: "I have re-

turned to the world of
academic medicine after
leaving MedicaLogic/
Medscape (now owned
byGE
Medical
Systems)
in early
2001. I
have
joined
the faculty in general
medicine at the Brigham
and Women's Hospital,
Harvard Medical School,
and I am director for
clinical information systems research and development at Partners
HealthCare System, Inc.
I'm having fun with students and research, and
still building clinical

�information systems.
Daughters Julia (9) and
Lillian (5) are wondering,
'Where is the snow?'
Wife Ursula King is making our new home and
considering work ...
eventually."
Laura L. Post, MD '87,

writes: "I have been living and working in
Saipan, Commonwealth
of the Northern Mariana
Islands (U.S.) for five
years now and am very
much enjoying medical
practice in a remote,
underserved area. I am
sorry that I was not able
to come to the reunion,
but the trip would cost
over $2,000 and taken
longer than 24 hours.
Maybe I will be ble to
make the 20th reunion. I
spend my days as the correctional psychiatrist at
the local prison and commute to the nearby Territory of Guam (U.S.) to
serve at their Medication
Clinic for seriously mentally ill adults. After
hours, I see private clients and on weekends do
competency and insanity
evaluations for the court,
disability and fitness-forduty evaluations in the
private sector, and opinions in personal injury
civil and sentencing mitigation in criminal matters. My partner, Judith
E. Avery, RN, MS (SUNY
at Buffalo '87), CNS and
I live in a beautiful house
overlooking the ocean
with our small dog, Max;

our medium-sized dog,
Sasha, and our large dog,

William Palmer Jr. MD. '90,

Boris." E-mail address is
drlaurapost@hotmail.com.

the move again.
Stephanie, Janee (12),
Jilian (9) and Jayson (2)

Pat Shaughnessy, MD '87,

and I relocated to
Winston-Salem, NC, in
june 2002. I have joined
another physician in pri-

writes: ''I'm in a twoman rehabilitation medicine practice in rural
Western Pennsylvania.
(I see Dennis Moll ins at
conventions.) I am
president-elect of the
Mercer County Medical
Society. My wife, Maggie,
and I have three daughters: Colleen, a freshman
in high school, Maureen,
12, and Kathleen, 11. All
are involved in music. I
am cantor and accompany at church. Our
"Farmette" is six acres,
and we have llamas,
sheep, chickens, etc. I'm
in Disney World's 20012002 promotional
video-biggest accomplishment to date!"
Anthony J. Bufo, MD '89,

writes: "I am a pediatric
surgeon in West Palm
Beach, FL." E-mail
address is: ajbcrb@
netscape.net.

Glen M. Ginsburg, MD '90,

pediatric orthopaedic
surgeon at the University
of Nebraska Medical
Center, has been promoted to associate professor. He has been on
the staff there si nee 1996.
E-mail address is:
gi nsy4549@yahoo.com.

writes: "We have been on

vate practice to work at
Whitaker Rehabilitation
Center. I have also assumed the outpatient
rehabilitation medical
directorship. We left
Indiana after eight years."

Andrew Feinberg, MD '95,
and Whitney (Orman)
Whitney writes: "Andrew and I got married

E-mail address is:
wpalmerjr@aol.com.

and have a two-year-old son, Ryan, and a

Susan J. Littler, MD '91,

ophthalmology in a private practice here in

PhD, is an attending in

Atlanta, and I am working part-time at a

OB/GYN at Mt. Sinai
Hospital. E-mail address
is: suejlittler@aol.com.

pediatric urgent care center."

on November 2, 1996. We live in Atlanta
baby due in June 2002. Andrew is practicing

Atif Zafar, BA '89, MD '94,

received the George W.
Thorn Award from the
University at Buffalo
Alumni Association during its annual awards
dinner held on April19,
2002. The award recognizes graduates under the
age of 40 who have made
outstanding national or
international contributions to their career field
or academic area. A medical computer scientist,
Zafar is clinical assistant
professor
in the
Department of
Medicine
at the In diana University (IU)
School of Medicine and
is on the staff of the

Regenstrief Institute, a
25-year-old research
foundation located on
the IU medical school
campus dedicated to the
study and improvement
of health and health care delivery.
Gonzalo Bearman, MD '97,

writes: "Regrettably, I
was not able to attend
the reunion this year.
All is well. I am an infectious diseases and public
health Fellow at Cornell
University in New York
City. I will finish the
program in july 2003.
Currently, I'm dedicating
most of my time to clinical research and an MPH
degree. Regards to all."

Dayo (Wilson) Lanier, MD '97,

wrote: ''I'm a pediatrician, living in Albany,
NY, with my husband,
Rob, and my nine-month
old son. I took this past
year off from practicing
medicine to stay at home
with my son, but started
back to work parttime
this june."
Stephen Milback, MD '97,

writes: "My wife, Cindi,
and I now have three
beautiful children ages 5,
3, and 16 months. We've
enjoyed living in San
Diego these past five
years and look forward
to a new adventure as we
plan our move to Japan."
E- mail address is: steve
milback@hotmail.com.
CONTIN U ED ON PAGE 4 8

Summ e r

20 0 2

luffale Physicia n

45

�•

e
.John Ambrusko,

named in his honor in 1988.

2002

After military service he

University of Buffalo School

LTJG, he returned to Buffalo

of Medicine. He was an All·

in private practice.

In his 80s, Ambrusko

returned to Buffalo and re·

John S. Ambrusko, a fonner

took on the role of father to

sumed his medical career,

American basketball player

Buffalo surgeon and Florida

two grandsons, 4 and 6

serving as chief of the head

and captain of the 1940

shaped the rest of Loeser's
career occurred in 1953,

The defining event that

public health official died on

years old, after their

and neck service at Roswell

Dartmouth team that won

April 25, 2002. He was 88.

mother, his daughter Sara

Park Cancer Institute. He

the Ivy League title. He

when he fell victim to polio

The youngest of nine

Tokars, was murdered near

also maintained a private

served in the Anny during

during the last major epi-

children of Hungarian immi-

Atlanta. Eventually her hus·

surgical practice in the Buf-

World War II, rising to the

demic in the Buffalo area.

grants, Ambrusko rose from

band, Atlanta attorney

falo area and served as a

rank of captain.

According to his brother,

humble beginnings to be-

Fredric Tokars, was convicted

clinical professor in UB's

come one of New York

of arranging the murder.

medical and dental schools.

State's most recognized and
respected surgeons.

Ambrusko's wife, the

Marchetta's colleagues

After the war, Sullivan

Eugene W. Loeser, MD '52,

was on the staff of Kenmore

he spent agonizing months

Mercy Hospital in the Town

in an iron lung, and only
after further months in re-

former Phyllis Eusterman,

describe him as a dedicated

of Tonawanda, served as

died in 1998. He is survived

humanitarian and skilled

chief of staff and surgery at

habilitation was he able to

cal degree, Ambrusko be-

by six daughters, Therese of

surgeon whose career was

Sheridan Park Hospital in

ambulate sufficiently to

After receiving his medicame a surgical fellow at

San Francisco, CA; Gretchen

marked by quiet service

the Town of Tonawanda and

work in the UB Respiratory

the Mayo Clinic in Roches-

Schaeffer of Newport Beach,

to his patients. He has

operated a private practice

and Rehabilitation Center,

ter, MN. When World War II

CA; Mary Bennett of

also been honored by the

for many years on Kenmore

where he later served as

broke out, he enlisted in the

Shrewsbury, NJ, Joni of

many medical residents

Avenue in the Town of

medical director. Loeser's

Navy, serving for several

Bradenton, FL, Karen Wilcox

he trained.

Tonawanda. A sports enthu-

personal experiences led

years before returning to the

of Buffalo, NY; and Krissy of

siast, he was team physician

him to introduce improve-

Marchetta was a diplo-

Mayo Clinic. In 1948, he

Woodstock, GA; and 11

mate of the American Board

for the Bisons baseball team

ments in feeding and

joined the surgical faculty at

grandchildren.

of Surgery, a fellow of the

in the 1950s and for the

breathing techniques to aid

American College of Sur·

Bills from 1960 to 1963.

patients in weaning from the

UB. He also opened a general surgery practice and in

rank Marchetta,

1950 helped the Sisters of

geons and a member and

Survivors include his

iron lung.
In 1958 Loeser relo-

past president of the

wife, the fonner Mary
Ferguson of Delray Beach

cated to Youngstown, Ohio,

Mercy found Kenmore Mercy

Frank Marchetta, a re-

International Head and
Neck Surgical Society.

Hospital, where he served as

spected oncologic surgeon

chief of surgery for 20

whose medical career

Survivors include his

years. From 1954 through

spanned more than 50

1978, he was chief medical

and Rose Hill, Ont.; a daugh-

to become director of medi-

ter, Elizabeth S. Bond of

cal education for its hospital

wife of 53 years, Jean; two

Wellesley, MA; a son, Ken·

association. During this pe-

years, died unexpectedly

daughters, Linda Marchetta

neth F. of New York City;

riod he introduced renal di-

consultant to Niagara

March 6, 2002, in his home

Wild, MD '76, of Williams-

and two grandchildren.

alysis into the local hospital.

Mohawk Power Corporation.

on Sanibel Island, FL. He

ville, NY, and Joanne

was 81.

Marchetta of San Francisco,

After cataract surgery
forced him to give up his

Born in Utica, Marchetta

Although he never re-

1am

• Loeser:

CA; a son, Dr. Charles of

attended Cornell University

East Aurora, NY; and five

William D. Loeser, died on

moved to Florida, where he

prior to earning his med-

grandchildren.

February 11, 2002, at 79

passed the state's medical

ical degree at the then-

board exam and began a

University of Buffalo Medical

new career as public health

School. After World War II,

years of age.

ames Sullivan,

Loeser was a native of
Buffalo and a graduate of

he served

James R. Sullivan, a former

County Health Department

in the U.S.

in Bradenton. He also served

Medical

as an associate medical ex-

Corps

sity of Buffalo ('41). Follow-

cally in his later years, but

Buffalo Bills and Buffalo

ing graduation from medical

his good spirits and humor

Bisons, died April 8, 2002,

school, he trained in inter-

never failed him.

with the

in Boynton Beach, FL, after

nal medicine at Jewish

a long illness. He was 85.

Hospital of Brooklyn and

forces

of his career. Post-polio

team physician for the

occupation

under General Douglas

who became close friends
and colleagues for the rest
syndrome slowed him physi-

aminer for the State of

agency, Ambrusko was re-

resume private practice and
joined a group of internists

Lafayette High and Univer-

Florida from 1980 to 1995.
As director of the Manatee

gained full strength, Loeser
felt the calling in 1964 to

surgical career, Ambrusko

director of the Manatee

46

SUMMER

Sullivan graduated from
Nichols School, Exeter and

Loeser is survived by his
wife of 55 years, Annette

completed his residency

Brown Loeser; a son, David,

under John Talbott, MD, at

of Needham Heights, MA;

sponsible for building a new

McArthur, attaining the rank

Dartmouth College prior to

Buffalo General. After a stint

daughters Ellen of West

health center, which was

of captain.

attending the then-

as a naval medical officer,

Roxbury, MA, and Cynthia

luffale Hp i cian

Summer

2002

�RELOCATION
HU T REAL ESTAT E ERA

Loeser Sandoval, of Daly

was an Erie County medical

where he practiced anesthe-

City, CA; and his brother,

examiner. He was also clini-

siology for two decades.

Eugene, of Jupiter, FL.

cal instructor emeritus of
rehabilitation medicine at UB.

er ert S. Wolfe,
Mrs. Herbert S. WoHe, RN,

Survivors include his

For the past 15 years,
Potenza had been medical
director of the health center

wife of 45 years, the former

at Geneseo State College.

Kathryn "Katie" Siegfried; a

He was also a past president

writes: "After Dr. WoHe had

daughter, Karen Vergo of

of the Livingston County

open heart surgery and he

Kenmore, NY; a son, Robert

Medical Society.

feH better, we headed for

of Santa Barbara, CA; a

Texas. We located in Mission, TX, at the Bentsen

cal care, often free, to indi-

NY; and five grandchildren.

gent patients. He received

.James mr

awards, and July 24, 1984,

Grove Trailer Park. We en·
joyed all the activities, and

many community service

the friends we made were

was declared Lucien A.

wonderful. Each year we

James lmre Szabo, of

stayed longer, and about

Winter Garden, FL, died

three years ago, we became

Monday, March 18, 2002,

permanent residents.
"Doctor's heaHh started
to fail, and each year he did

Potenza provided medi-

brother, Nicholas of Buffalo,

at age 84. Szabo, a Buffalo
native, moved to Central
Florida in 1953. He was a

less. He was hospitalized

member of the American

many times and then on

Association of Physicians

January 26, 2002, he went

and Surgeons, American

home to be with the Lord he

Geriatrics Society, American

Potenza Day in Buffalo.
Survivors include his
wife, the former Susan Baer;
a daughter, Evelyn Frank of

Lewiston, NY, Michael

both of Amherst, NY,
Andrew Bellman of

loved and served all his life.

Gerontologic Society. He is
survived by his wife, Nancy;

59 years in June."

daughters, Lisa A. Stone of

and a sister, Carmello

Oviedo, FL, and Nancy J., of

.James N. "Bo"

Menno of Cheektowaga .

Gainesville, FL; son, lmre A.,
of Winter Garden, FL.

former chief of rehabilita-

Cheektowaga, NY, and Paul
Bellman of Berkeley, CA;

ary Miller, MD

Lucien A.

Gary Miller, died unexpect-

Affairs Medical Center in

Lucien A. Potenza, died

heart attack while jogging.
He was a professor of

tion medicine at Veterans

edly May 25, 2001, of a

Batavia, NY, died March 26,

April 1, 2002, in Strong

2002, in Town of Tona·

Memorial Hospital,

pathology and urology at

wanda, NY, after a long ill-

Rochester, after a brief

the University of Colorado

ness. He was 73.

illness. He was 71.

A native of Buffalo,

Potenza was born in Buf·

HeaHh Sciences Center in
Denver, where he was also

Schmitt attended Canisius

falo and graduated from

College and the then-

Canisius High School. At the

urologic

University of Buffalo School

University of Buffalo School

cancer

of Medicine he served as

research.

as a surgeon and lieutenant

president of his class.

He was

commander in the Navy dur-

Following the war, he

•
•
•
•
•
•
•

Nationally trained relocation experts
Complete family needs analysis
Global home sale assistance
Special services for seniors
Full community tour
A complete cost of living analysis
A list of all school systems
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• Complete spousal placement
assistance including resume
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• 24 hour o r less response time
• Confidentiality assured

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For over 30 years

both na-

Potenza maintained a gen·
eral medical practice on

Totally customized
service portfolio including

director of

of Medicine prior to serving

ing the Korean War.

Call for a free relocation portfolio
regarding your destination city.
Call 1-800-688-1170 or go on-line
and visit our web site at
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Bellman and David Bellman

We would have been married

James N. "Bo" Schmitt,

...we help people move!

Buffalo; six sons, Daniel of
Warner, NH, Mark of

tionally and internationally

headed rehabilitation medi-

Buffalo's west side. He was

in the field of prostate can-

cine at the veterans hospi-

also a former president of

cer research.

tal, and until the mid-1970s

Lafayette General Hospital,

&lt;D)

Hunt ERA Relocation Center
5570 Main Street
Williamsville, New York 14221-5410
Email : huntrelocation@huntrealestate.com

S 11mmer

2 002

luffalo Pbysician

47

�CLASS

I

CONTINUED FROM PAGE 45

Kristen Andresen, MD '98,

Milford, CT, writes:
"After finishing my
residency in internal
medicine at the University of Rochester and
marrying a fellow resident, I've moved to
Connecticut, where
my husband, Scott, is
doing a fellowship at
Yale. I'm presently
working as a hospitalist
and enjoying life with
Scott and our two best
friends: Shadow (black
lab) and Sonner (golden

NOTES

retriever)!" E-mail is:
skskibo@ comcast.net.
Lisa E. Heichberger, MD '98,

Tacoma, WA, writes: "I
completed my family
practice residency at
Hamot Medical Center
in Erie, PA, where I
served as chief resident.
This past year, I was
granted a fellowship in
Rural Family Medicine at
Tacoma General Hospital
in Tacoma, WA. My husband, Mark Peterson,
and I presently reside in
Tacoma." E-mail address
is MPeter32@aol.com.

Michael P. Melman, MD '99,

Sue Miller, MD '99, writes:

writes: "After graduation
I spent a year at the NIH
completing research in
the field of pediatric
hematology/oncology.
Currently, I am a pediatric resident at Emory
University in Atlanta and
will be applying for a
fellowship in pediatric
emergency medicine.
Hope all is well with my
fellow alumni! E-mail
address is: mpmcrew@
aol.com.

"Larry and I are excited
to be moving to Seattle,
WA, in june. I finished
my pediatrics residency
at Children's Hospital of
Buffalo and will be starting my fellowship in

CELEBRATE THE SEASONS OF YOUR LIFE AT AMBERLEIGH

48

I u II a II Ph J sic i a 1

Summer

2002

neonatology at the
University of Washington. Larry completed
his MBA and is currently
a consultant with
Andersen. We hope
everybody is doing well!"
E-mail address is:
smm4S@hotmail.com.

E-mai

�Held at the Buffalo/Niagara Marriott,
THE 65TH ANNUAL SPRING
CLINICAL DAY AND
REUNION WEEKEND WAS A
TIME FOR OLD FRIENDS AND
CLASSMATES TO REUNITE
AND REMINISCE ABOUT THEIR
MEDICAL SCHOOL YEARS .

Dean Michael Bernardino
briefing the luncheon crowd on mam of the
positive changes taking place at the school, as
well as ongoing challenges.

..-----

Stephen Pollack, MD '82,
vice president for the \!edtcal Alumm
Association, was ke} to makmg the day
a success.

�p H A R M A

c

0 p 0 E .I A

OF MEDICINE
COLLECTION PRESENTS
PHARMACOPOEIA

This illustration was digitally reproduced from
offizinellen Gewachse, a

four - volume edition of
pharmaceutical plants
and their medicinal uses ,
published in German in

1863. The pharmacopoeia
by Otto Karl Berg (18I5I866) is part of the Rob e rt L. Brown History of
Medicine Collection ,
located in the Abbott Hall
Health Sciences Library.
Pi ctured is the Pomegranate, one of a series

of botanical images digi tally restored as part of
an initiative to preserve

and highlight unique
r e sources

from

the

library's collection.
Reproductions

are

available for purchase
through the library, and
can be viewed online at
iMedia. buffalo .edu/ art/ .
Image restoration was
performed by iMedia ,
the instructional media
se rvices department of
Computing and Info rma tion T echnology, University at Buffalo.

b,

R P 000 3- 02

.E

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                    <text>�l1ffale r•ysicial
ASSOCIATE VICE PRES I DENT FOR
UNIVERSITY COMMUNICATIONS

Dr. Caro le Smith Petro
DIRECTOR OF PERIODICALS

Sue Wuetcher
EDITOR

Dear Alumni and Friends,

Stephanie A. Unger
ART DIRECTOR

&amp; DESIGN

Alan f. Kegler
David]. Ri ley
N N OVEMBER,

I ATTENDED T HE ANNUAL MEETING of the Association of American Medical

Colleges (AAMC) in San Francisco. Because the meeting is a forum for discussing topics
affecting academic medicine nationwide, it serves as a valuable bellwether for deans and
other school leaders whose responsibility it is to prepare as best they can for foreseeable
trends, as well as for sudden exigencies.

DESIGN ASSISTANT

Karen Lichner
CONTRIBUTING WRITERS

Lois Baker and Ellen Goldbaum
PRODUCTION COORDINATOR

The financial status of medical schools was a prominent theme at the meeting due to the
fact that as many as 70 percent of all schools are having financial concerns. A number of
deans l spoke with experienced cuts between 4 and 8 percent in their school's budgets last
year and are expecting further cuts of about 4 to 6 percent for the coming year.

Cynthia Todd-Flick
UNIVERSITY AT BUFFALO
SCHOOL OF MEDICINE AND
BIOMEDICAL SCIENCES

Dr. Michael Bernardino, Dean

As a result of the current economic environment, many universities
are postponing building projects; others that have built are not sure how
they are going to pay for the buildings or maintain them. This reflects a
notable difference in how our school operates because the state builds
and maintains our buildings.
Although we may have smaller cuts in our school's budget, these cuts
are in some ways more painful because labor and union laws preclude us
from exercising the flexibility that others schools have in implementing
them. In general, however, I feel the financial status of our school is currently no worseand no better-than many of our peer institutions.

TEACHING HOSPITALS

An especially controversial topic at the meeting was physician shortages, which
participants spent an entire day debating. As you are aware, the number of residents was
capped in 1996 by the Balanced Budget Act, a move that was endorsed by the AAMC and
a number of other groups.

EDITORIAL BOARD

Dr. John Bodkin
Dr. Martin Brecher
Dr. Harold Brody
Dr. Linda f. Corder
Elizabeth Volz, Class of 2005
Dr. ]ames Kanski
Dr. Elizabeth Olmsted
Dr. ]ames R. Olson
Dr. Stephen Spaulding
Dr. Bradley T. Truax
Dr. Franklin Zep lowitz

ow, for the first time, the wisdom of this move is being

questioned due to the fact that, nationwide, there is a shortage of specialists in a growing
number of fields.
This is a debate that will directly impact our school, which ten years ago moved sharply
toward training primary care physicians and away from training specialists, as did many
other schools.
l don't know when or how the pendulum is going to swing back to a point that better
reflects the needs of our society, and l certainly don't advocate for reversing current trends
by instituting equally sharp upward adjustments in specialist training. However, most
leaders in our school's administration feel, as I do, that we currently have too many primary

Erie County Medical Center
Roswell Park Cancer Institute
Veterans Affairs Westem
New York Healtltcare System
KALETD.~ HEALTH:

Tlte Buffalo General Hospital
Tile Cltildren's Hospital of Buffalo
Millard Fillmore Gates Hospital
Millard Fillmore Suburban Hospital
CATHOLIC HEALTH SYST£\1:

Mercy Healtlr System
Sisters of Cltarity Hospital
Niagara Falls Memorial
Medical Center
@

IIIYEISITY AT IIFFALI ,
TIE SliT£ UIHISJTY If lEW Ylll

care and internal medicine residents and that it makes increasingly good sense to gradually
move some of them into specialties.

Letters to the Editor

Lastly, a topic that concerned many at the meeting is the amount of debt medical
students are assuming upon graduation. (It was reported that the mean average debt for all
medical graduates in 2002 was $103,855. When specialty training is factored in, the amount
of course rises.) This is an issue that we as educators must address. We must find a way to
decrease the significant debt burden of our students.

J. R.

4-A

.i.:. ,_A-&lt;)

~.BERNARDINO ,

MD, MBA

Dean, School of Medicine and Biomedical Sciences
Vice President for Health Affairs

Buffalo Pltysicratr is published quarterly
by the University at Buffalo School of
Medicine and Biomedical Sciences in
cooperation with the Office of
Communications.
Letters to the Editor are welcome
and can be sent cfo Buffalo Pltysicimr.
330 Crofts Hall, Unrversity at Buffalo,
Buffalo, NY 14260; or via e-mail to
bp-notes@buffalo.edu. Telephone:
(716) 645-5000, ext. 1387.
The staff reserves the right to edit
all submissions for clarity and length.

T~

~

University at Buffalo
TheStateUniversityofNt:wYork

�VOLU M E

37,

NU M BER 0

p

H

y

c

s

A

N

Features

2

Family Medicine, aGlobal Perspective
Refugee Cultural Competency
Training Program gives students
an opportunity to work with
patients from other cultures
BY

12

S . A. UNGER

ADegree of Latitude
Popular biomedical education
program helps young scientists
make smart career choices
May Shogan, left, translating coordinator atthe lnternationallnstitute, and Luis Zayas, PhD, right, a
medical/cultural anthropologist and research instructor in the Department of Family Medicine, helptrain
medical students and residents in University at Buffalo's new Refugee Cultural Competency
TrainingProgram, developed by KimGriswold, MD'94. Turn to page 2 for more.

BY NICOLE PERADOTTO

16

On Course
A conversation with Margaret
Paroski about medical education,
curriculum and admissions

COV ER

PHOTO

AB OUT THE

32 Update on
Convocation

21 Alpha Omega
Alpha Scholars

22 Sung and
Medical Alumni
Association
scholarships
Golden Mind
and Body
Lecture

Lawley named
Distinguished
Medical
Alumnus

41 Messages from
reunion class
chairs

43 Alumni
President's
column

faculty, staff,
students and
alumni

30 Western ew
York Pioneers
of Science
In Memoriamjohn Edwards

work in UB's
Center of
Excellence in
Bioinformatics

34 The Living
Anatomy
Program

36 Women's
Health
Initiative spins
off new projects

BY

COVER ,

RHEA ANNA
SEE

PA C E

40 The Road
Best TraveledKim Griswold's
circuitious
route tomedical school

other alumni

11

��Family Medi ine:
aGlobal

I

I

1

I

�~-~-

- - - - - - - ·

~-.

Despite the presence of interpreters,

attention to protocol and the neat stacks of paperwor , the

participants were not convened to resolve border disputes, monitor free elections, intercede on behalf of
warring parties or debate the merits of armed intervention.
Instead they had gathered to welcome new arrivals to America-men, women and children forced to flee
their homelands for safety-and to help these refugees learn how to navigate the labyrinthine health-care
system that awaits them in their new country.
Conspicuous among this group gathered at the Columbus
Health Center were two young men and a woman in starched
white coats, all first-year students in the University at Buffalo School of Medicine and Biomedical Sciences, who were
participating in the meeting as part of an innovative educational program aimed at increasing their cultural competency while improving access to preventive and primary care
services for refugees in Western ew York.

An Immersion Experience
The voluntary program, which is open to all students and
primary care residents at UB, was developed by Kim Griswold,
MD '94, MPH, an assistant professor of family medicine, who
has garnered a three-year, $393,933 grant from the ew York
State Department of Health to support its integration into
UB's medical school curriculum.
A joint sponsor of the program, along with UB's Department
of Family Medicine and Kaleida Health's Columbus Health
Center, is Jericho Road Family Practice (also located on Buffalo's
West Side), which is operated by Myron Glick, MD '93 UB
assistant professor of clinical family medicine. Assisting the two
clinics with implementing the program are the International
Institute of Buffalo and Journey's End Resettlement Services.
"Our strategy is to offer a concentrated cultural-immersion

l1ffale Hysiciaa

W11!t e r

2 003

experience to students and residents at evening clinical sessions that
serve only refugee patients," says Griswold. "The students work with
people from Rwanda, Sudan, Somalia, Ethiopia, Congo, Kosovo,
Bosnia, and Cuba, as well as from a number of Asian countries."
All refugees seen in the program are legal immigrants who are
being resettled through the federal government, according to
Glick. "They receive Medicaid for a year, during which time they

are expected to learn English, find a job and provide for their
family," he explains. "Some people do incredibly well with that.
There are a lot of success stories, but there definitely are those
who struggle, and health care is a big part of that struggle because
even when they do get jobs, they' re often low-paying and so don't
provide health insurance."

T

he program, formally titled the Refugee Cultural Competency Training Program, builds on a pilot project developed
over the past two years by Griswold, UB medical students and
volunteers in which medical students conducted health screening of refugees during monthly "health nights" at one of the
participating clinics.
Clinics for the newly funded program take place from 5:00 to
10:00 p.m. and are dedicated to medically evaluating refugees
who have recently entered the country. Prior to seeing patients,
the students attend an orientation discussion presented by staff

�Pictured,

left

to

right, May Shogan,

from one of the resettlement agencies, a cultural/medical anthropologist, a physician, and a case worker from either Journey's End
or the International Institute who is informed about the medical,
psychosocial, financial, cultural, gender and legal issues of the
refugees to be seen.
"The orientation focuses on helping the students know
what to expect during the clinical session, " explains Griswold,
who adds that each session is limited to a maximum of three
students to assure that they receive as much one-on-one training as possible. "In particular, they are briefed on what type of
psychosocial problems the refugees might present with; for
example, traumatic stressors such as torture, mutilation, religious persecution, murder of family members, or loss of home
and possessions. They also learn about the medical problems
common to the refugees ' homeland, such as parasites and
infectious diseases. "
In the orientation session, the students also are instructed in
how to address the problem of translation and how the translation
will be handled during the upcoming session-whether through a
telephone translator, physician or health-care translator.
Finally, the program's medical/cultural anthropologist, Luis
Zayas, PhD, research assistant professor in UB's Department of

Family Medicine, teaches the students about basic principles of
medical anthropology and introduces them to the concept of
"culture," as well as to methods for "taking the role of the other. "
In discussing this latter concept, Zayas and a staff member at the
International Institute talk to the students about the importance of being open, interested, empathetic and tactful with the
patients, attributes that will assist them not only in building
trust, but also in gaining meaningful information about the
patients' lives.
Zayas, an experienced ethnographer who is fluent in Spanish
and Portuguese, also briefs the students on the importance of
note taking while performing a history, as well as the etiquette for
doing this effectively, yet unobtrusively.

The Preceptor and the Process
After the orientation session, the students spend several hours in
the clinic, where they are encouraged to practice their interviewing and listening skills in order to gather knowledge about a
patient's life story, as well as facts about his or her health history.
Giving the refugees an opportunity to tell their stories serves as
a means to help validate the often bewildering and painful
experience they have undergone as an immigrant, according to

Winter

2003

l 1 fl al• Hysicin

5

�Griswold. "Too, a patient's life story can include important cultural, emotional, sociopolitical and economic events not captured in a standard medical history," she explains.
Glick, who leads similar evening sessions at his Jericho Family
Practice, recalls an encounter he had with a patient several years
ago that reinforced for him the importance of knowing as much
about a refugee's past as possible in order to deliver effective care.
"I met a woman from Sudan who was especially sad," he says,
"and when I heard her story-that she had lost her three older
children in a war, and that, basically, they were killed right in
front of her and her three younger children-this allowed me to
understand her a lot differently than if I didn 't know that part
of her story.
"But we hear countless stories like this," he continues. "The
refugees come with a lot of trauma in the past that can end up
causing depression , post-traumatic stress disorder, marital conflict or domestic violence-a lot of psychiatric issues that are
hard to put a finger on and are hard to treat, especially if you
don't know their stories. "
Despite the importance of gathering information about a
refugee's life story, Griswold is quick to tell the students that they
need to be patient in the interview process and that they don 't
need to obtain everything in one visit.
"Often the patients are not ready to divulge their histo ry, whatever it is," she says. "For example, torture is a huge issue, and we need
to ask about it sensitively. On the first visit, you're not going to say,
'Okay, tell me about your torture.' You can't be that direct; you

6

laffala Hysiciu

Winter

2003

have to establish the rapport, the trust. And it may take many visits
before a person is comfortable talking about things like that."
In addition to taking a medical history and listening to
patients' life stories, students also conduct physical exams
(depending on their level of training), or assist a resident or
attending physician. Further data are collected on health behaviors such as smoking, drinking and the patient's understanding of health in general.

0

nee the exams are completed, the students are taught how to
review the patient's story and objective findings, make an
assessment and plan with the preceptor forthe patient's continuing medical and psychosocial care.
Refugees in need of psychiatric care or mental health services
are referred to Lakeshore Mental Health Counseling or to Child
and Adolescent Treatment Services, as well as to other agencies
and practices collaborating with the program.
Attention also is paid to the refugees' oral health, as many
have never seen a dentist in their lives and are in urgent need of
such care, according to Glick, who is hoping to establish a similar
referral network among area dentists.
At the close of the clinic session, the students then re-group
in the conference room for a half-hour debriefing session that
is conducted in a focus-group format by Zayas and the supervising physician.
"We ask the students to talk about all aspects of their clinical
session with the refugee," says Griswold, "and we pay special

�attention to their emotions, especially if they have had few or no
experiences with a refugee population."
In addition to monitoring the students' emotional responses
to their patient encounters, the instructors ask the students to
summarize what they learned as it pertains to cultural issues and
to talk about hurdles they may have encountered related to
translation. They also ask the students to suggest ways they feel
the experience could be improved.
As part of the program, the students--each of whom must
commit to a minimum of two such sessions in order to participate-are asked to keep a diary in which they record all of their
encounters with refugees, whether they be within the formal
context of the program or in extracurricular activities they undertake on their own, and to complete a written evaluation of their

experience in the program. They also are required to write a short
paper linking the clinical experience to the lecture aspect of the
program and to describe how they feel they benefited from participation in the program. The data obtained during the debriefing
sessions are recorded and will be qualitatively analyzed by Zayas at
the end of the program in order to assess its success, including how
effectively it was integrated into the medical school's curriculum.

Life Stories. LiYe
The first-year students participating in the late October session at
Columbus Health Center were Lynne Learned, Justin Spooner
and Brian Eichner. Prior to the start of the session, they were
told by Griswold to expect the arrival of two refugee families as
the evening progressed: one from Vietnam and the other from
Bosnia. They also were reminded that once the refugees and the
other participants arrived, introductions would be made and
the refugees would be invited to tell the group as much about
themselves as they wished.
After this discussion, Griswold, Learned and Spooner would
escort the refugees down the hall to the clinic to begin the clinical
exam sessions.
Eichner, who, unlike his two classmates, had not yet attended

an orientation session, would remain behind and be briefed by
Zayas and a representative from the International Institute,
later joining the others in the clinic.
As it was the dinner hour, snacks and beverages were passed
around the table, and an air of warmth and collegiality filled the
small room as others trickled in and introductions were made.
Among the first to arrive were the translators from the International Institute: Bong Vu, a Vietnamese man who has been in the
United States for 30 years, and Vesna Demirovic, a Bosnian
woman who came to the United States five years ago with her
husband and 12-year-old daughter. They soon were joined by
Barbara Burns, a social worker and a conPictured,leh to right, are
sultant on the grant, and Sister Mary Judith,
medical students Justin

a case worker at the International Institute. May Shogan, an
immigrant from Jordan who has been in the United States for 15
years, also arrived and sat with Zayas, with whom she partnered
to present the orientation session for Eichner. Fluent in English,
French and Arabic, she, too, is a consultant on the grant, with
special expertise in cultural issues and refugee assimilation.
Rounding out the group were Griswold and two staff members
in UB's Department of Family Medicine who work closely with
her to administer the day-to-day operations of the grant: Joan
Kernan and Christine Wagner, a social worker.

A

fter about 15 minutes, the first refugee family arrived: a
husband and wife and two teenage daughters from Vietnam .
The parents were seated next to Vu at the head of the table, while
the girls sat to the left of their mother.
The girls immediately began interacting with the group, helping themselves to the food and drink that was offered and playfully trying to sound out how to pronounce words printed on the
label of a pop bottle. The younger girl, clearly the most outgoing
and spontaneous, stood up to offer to pour a cup of soda for the
social worker seated across the table from her and engaged in a
cheerful pantomime with Kernan, who admired the girl's blouse as
she took off her winter coat and settled into her chair. Although

Winter

2003

l affal1 Plysiciu

7

�little English was spoken by either girl, clearly they were relishing
the encounter and eager to dive headlong into their new life.
Their father sat quietly and appeared anxious and withdrawn,
the skin on his face deeply creased and worn in contrast to the
bright, fuchsia-colored sweatshirt that reached high on his neck,
forming the middle layer of several shirts he wore on this chilly
evening. The girls' mother also sat quietly, her reserve broken
only when Vu drew her into conversation in low tones. Occasionally she cast a quick, guarded look around the room and
seemed mildly amused with her daughters' chatter.

H

aving been informed that the Bosnian family was experiencing-delays in their transportation to the clinic, Griswold
decided to move ahead and formally opened the session, asking
those in the room to introduce themselves to the family.
Once the introductions were completed, Spooner, upon request, briefed the family about what to expect during the clinical
exam, after which he and Griswold addressed a few questions
from the younger daughter.
Zayas then gently encouraged the parents to tell about themselves, if they wished: Where were they from? What was life like
in their village?
The father, too shy to speak, deferred to his wife. After a brief

pause, she began talking rapidly while holding out both hands
and repeatedly flashing her fingers to show the numbers "two"
and "five," as if convinced her words alone could not convey
what she needed to explain.
The younger daughter, hearing her mother's sudden outpouring of words, implored her to slow down for the interpreter,
tugging on her mother's arm and making a pumping, brakelike motion with her hands.
Her distraught mother appeared not to notice and proceeded
with her story unabated.
When she stopped after a few minutes, Vu paused to collect
his thoughts, and then slowly turned to the group and spoke. He
explained that she had described how she and her husband had
met and married. She also said that they were from a rural
province in South Vietnam, about 80 kilometers south of Saigon.
When the communists took over, it was very hard because her
husband worked for an American company. They gave them all
kinds of problems, so it was very difficult to live under the new
regime. They didn't think they could survive in Vietnam. Two of
their children are here with them; five still are back in Vietnam.
Griswold thanked the mother for sharing some of her story and
then asked Vu to explain that she and two of the students were going
to escort the family down the hall to begin the clinical session.

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for now, they communicate by writing letters.
fter they left, and before the orientation for Eichner began,
The youngest of the two daughters with them attends a local
Sister Mary Judith, the caseworker, made a few follow-up
high school and the older takes English classes at the Internacomments about the Vietnamese family. She explained that in
tional Institute.
1995, immigration policy in the United States changed and, as a
They are happy to be in the United States, but the father worresult, children who are over age 18 or who are married cannot
ries about finding a good job, although he currently does enough
accompany their family. She surmised that the couple's five other
piece work for the family to live without public assistance.
children remained behind for that reason.
Learned, who examined the mother and two daughters, exLater that evening, during the debriefing session, Learned and
plained that she was impressed with their closeness.
Spooner shared additional information that they had learned
"They seemed very loving and concerned for each other," she
about the family during the clinical session.
said. "They freely discussed sensitive sexuality and gynecological
They explained that the parents are in their late 50s and have
five adult children in Vietnam. The family had been in the counquestions, even though neither girl is sexually active nor has a
boyfriend, something they believe they are
try about four months, and they hope that someday the
far too young for because, in their culture, it
older children also can come to the United States but,
Betty Lim, Class of 2003
means marriage."
On the whole, Learned concluded,
"the entire family was quick to laugh
and were very loving toward one another and seemed happy. I found them
easy to talk with and was even invited
to come to their home. It was sad
leaving them in the end."
Shortly after Eichner's orientation
session with Zayas and Shogan ended, the Bosnian couple arrived and
were seated with their interpreter,
who introduced them to the others
and then talked quietly with the couple
for a few moments.

B

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oth appeared to be on the brink
of exhaustion. The man's thin
cheeks, stubbled with whiskers, were
sunken in his face, and his eyes were
red rimmed and bloodshot, as if he
had not slept for days. His wife's pallor was gray and her brown eyes were
faded to a lusterless amber. Sturdily
built, she sat upright in her chair, tensely dangling her purse over the side of the armrest and
staring vacantly around the room, her occasional words to the interpreter revealing broken
and missing teeth, similar to her husband's.
In a short while, Griswold reappeared to talk
briefly with the interpreter and, because the
hour was growing late, she and Eichner then
escorted the couple to the exam area .
Following the clinic sessions, the refugees
returned home and the group reconvened in
the conference room to debrief the students.
In the debriefing session, Eichner, who had

Win t er

2003

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earlier that the remains of her husband had been found in a mass
grave in Srebrenica; she had then been asked to describe his
personal effects over the phone.

The Demographics of Doctoring
While the experiences students gain through this intensive
program may seem exotic to some, Glick and Griswold both
point to the fact that, more than ever, such experiences are
increasingly pertinent to the practice of medicine in the
United States and will teach students important clinical
skills no matter where they eventually practice or whom they
choose to serve.
In his Jericho Family Practice, Glick estimates
that he sees patients from approxiParisima Mirzakazemi. MD
mately
50 different countries around the
interviewed the Bosnia woman, shared with the
world,
some
20
to
30
percent
of whom are refugees.
group more about the family's story.
"More
and
more
of
our
country
is becoming increasingly
He explained that the couple, in their early 40s, has three sons,
diverse,"
he
says.
"And
whether
you
end
up practicing in rural
the oldest of whom was shot in the head but survived. They had
been in the United States for four months and speak very little Iowa or on the West Side of Buffalo, you're going to end up dealEnglish, so are taking classes at the International Institute. They ing with folks who are different from you and who come from
are Muslim, from a small village in northeastern Bosnia, and the different places, so I think it's wise early on in your training to get
husband is an environmental scientist. The wife lost her brothers exposure in a controlled setting such as this program affords."
Too often, the first clinical encounters medical students have
in the war, and her mother also died recently. She has several
with
people from other cultures take place in an emergency
sisters in the country, one of whom had been notified two weeks

10

lulfalo Hysiciaa

W ill t er

2003

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room, according to Glick. Because of the hectic nature of this
setting, the encounter often becomes a source of frustration for
the student, instead of a potent learning experience, he feels.
"One of the things that this grant does is it allows us to bring
students in for an evening that is fairly slow paced," says Glick.
"So they get a chance to just go in and talk with the patients, and
that gives them a chance to give in a different way than if the visit
were just about a medical problem. This is incredibly important
because if you don't see people as people, if you don't see them for
who they are and where they come from, then you're not going to
give them the kind of care that you really should be giving."

S

pooner couldn't agree ~ore with G~ick's .assessment of the
merits of the program. I feel workmg with the refugees IS
the most rewarding activity I participate in," he says.
"The refugee population needs our help to get acclimated to
American culture and lifestyle," he adds. "Each person brings
with them a history of family, beliefs and knowledge that varies
greatly from my own, and I feel I can learn a great deal from
listening to them. Also, interviewing people across a language
and cultural barrier is challenging and educational. Prior to this,
I really took language for granted!"
First-year student Brian Eichner, who previously worked
with migrant farm workers from Mexico, says he's interested in

learning about the health-care needs of refugees because they are an underrepresented
group that has few advocates, and by immersing himself in their lives, he hopes to learn
about how to help them. This, he adds, "might
also shed some light on aspects of my own
family's immigration experience generations
ago and so help me to understand my past on
a new level."
Having met and talked with the Bosnian
couple in detail during their clinical visit, he
says he was most impressed with their bravery.
"The mother spoke to me as openly as she
could about her struggles in Bosnia, even
though it was clearly difficult for her to do,
and she eventually changed the subject,"
he explains .
"However, in that brief time, I felt that I
made an emotional connection with her and
gained her trust, if for nothing more than a
minute; but that was truly a powerful feeling,
especially when working with someone who
has had to endure so much."
Eichner feels it would be valuable for anyone working in health care to be exposed to the
type of patient encounters he has experienced
through his participation in the program.
"It's very easy for us to get caught up in our own daily
struggles and to lose sight of how lucky most of us are," he says.
"Experiences like this remind me of why I am working so hard
in medical school and of how blessed I am to have the opportunities and freedoms that I have in my life."
CD

Pictured on the cover is the
Nzotungicympaye family
from Burundi. Left to right.

back row: Agnes Musoni ,
holding five·month·old
Nelson Peary Nzo; and
Protais Nzotungicympaye,
holding Franklin Sijeniyo.
age three. In front is She ilia
lngabire, age 7. The family
immigrated to Buffalo in
January ZOOZ via Rwanda.

��Progran1 helps young scientists
n1ake smart career choices

0
f-o

~&lt;
"'
"'

p..

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...J

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u

z

�One of the great advantages of the program is that you get
to explore different disciplines and choose the one that you
prefer the most.
"!thought, 'What a novel idea.' owl don't have to make
an uninformed decision about what l want to do for the
rest of my life," recalls the Minnesota native, currently a
fifth-year IGPBS student in toxicology. "What sold me most
on the program was the prospect that interdisciplinary
training in biomedical research would open the most doors
for my future."
Apparently, quite a few students feel the same way.
Since the program's inception in 1997, the number- and
caliber-of applicants has exceeded the expectations of
UB's staff and faculty.
"As soon as we set it up, our enrollment increased,"
notes Suzanne G. Laychock, PhD, senior associate dean for
research and biomedical education. "The students have
responded extremely well."

A

ll involved with establishing the program agree that get-

ting it off the ground was an incredible undertaking.
From developing the curriculum and creating new classes to
uniting faculty members and determining the best ways to
recruit students, it required participation from dozens of
different voices. "We were moving graduate education out
of the medical curriculum, and that was revolutionary for
us," says Lachock. "There was a lot of dissension on how
things would go, and which courses would be given, but we
had to get beyond that. The program went forward and now
everyone's on board."
The faculty's dedication to the program has paid off in
more ways than one. With the IGPBS attracting so many
applicants, the admissions committee can be more selective
in the candidates it chooses.
"In the past couple of years we have been competing
very well with institutions such as Cornell, University of
Rochester and St. Louis University," says Elizabeth Hayden,
staff associate for Graduate Biomedical Education. "We
have brought students in from as far away as Texas and
Utah, and all over the East Coa t."
And just what type of student is attracted to the interdisciplinary approach?
According to Anthony Campagnari, PhD, former director of recruitment and admissions for the IGPBS and professor in the department of microbiology, the program
is geared for students still looking for their research focus.
"We attract those individuals interested in multiple disci-

14

laffall Hysician

\V inter

2003

plines, and those who are not ready to commit to one single
program," he says.
"The students are very creative in terms of being able to
think about things they would like to do," adds Laychock.
"But many of them are unwilling to say they would like to
do something specific because their undergraduate programs didn't provide them with the breadth of information to make that decision."
Even students with predetermined interests often favor
the IGPBS over a traditional departmental program because it provides them such a strong foundation in the
sciences. Of those students, Laychock notes, roughly 80
percent are open to the possibility of changing fields.

~e program's first graduate can count himself among that

.1_

group. In the summer of 1997 Mohamed R. Mohamed
came to UB as part of a training program jointly sponsored
by the U.S. Agency for International Development and the
Egyptian Ministry of Health. Although he planned to apply
to the microbiology department's PhD program, he was
encouraged to instead apply to the IGPBS. In June of2001,
Mohamed received his PhD-not in microbiology, but in
biochemistry instead.
"Of course, I would not have been able to change majors
ifi wasn't in the IGPBS," says Mohamed, who is conducting
postdoctoral research at UB. "One of the great advantages
of the program is that you get to explore different disciplines and choose the one that you prefer the most."
The program is also popular because it equips students
with a knowledge of various fields, which is considered a
desirable trait among potential employers, according to
Richard Rabin, PhD, director of IGPBS and professor of
pharmacology and toxicology.
"Gone are the days when the scientists went to their labs
by themselves and did their own thing," says Rabin, "That
just doesn't happen anymore. There's a lot of interaction
across fields.
"Of course, students have to specialize; you can't be a
jack-of-all-trades. But you have to have an appreciation for
the other fields to know what their needs are. Students get a
broad experience from the IGPBS rather than immersing
themselves immediately in a field and getting myopic."
The IGPBS's first-year curriculum includes mandatory
lecture courses in cell biology and biochemistry as well as a
course on the principles of lab techniques. In the spring
semester, students are asked to critique and present papers
in a seminar series designed to hone both their analytical and
communicative skills. Elective-course options also help

�students explore new fields of interest. During
the first year, students are required to rotate
through at least three labs-and they have the
option of working in a fourth-allowing them
an opportunity to narrow down their areas of
interest and determine their PhD adviser.
"These lab rotations are very meaningful experiences," Rabin says. "They're 12 to 20 hours
per week and half a semester in length. The
students are in there learning new techniques,
getting involved to see how they like it and, from
the investigator's mind-set, to see how they do.
"They are really in the thick of things,"
he adds.
In the spring of the first year, students are asked to rank, in order of preference, the three faculty
members with whom they would most like to
work. The match is made-with the vast majority
of students receiving their first choice of labsonly after it's certain the professor has the funding
and space to accommodate the student. In this
way, the students differentiate into PhD programs
in anatomical science, biochemistry, biological
science, biophysical science, microbiology, neuroscience, oral biology, pathology, pharmacology,
toxicology, physiology or structural biology.

S

cott Severance, currently in his fifth year of
the program, works in the biochemistry lab of
Daniel Kosman, PhD. For Severance, one of the most alluring
aspects of the program is the fact that the courses are tailormade to his needs, not those of an aspiring physician.
"Although we are associated with a medical school, we do
not take medical school classes," says Severance. "Medical
school classes are great if you are going to be a doctor, but
the instruction, examinations and expectations are different in a graduate school class.
"It would be much easier to have the IGPBS students
fulfill their course requirements by taking medical school
classes, as is the case at many other schools," he adds. "But
the directors of the program have done just the opposite."
Another bonus of the program comes from an administrative point of view: With the creation of the IGPBS, the
recruitment process has been dramatically streamlined.
"Previously, each department had to have its own recruitment brochures, and they had to support financially all
the recruitment activities," Laychock says. "That was a very
expensive and time-consuming undertaking, and we were

not necessarily reaching the students we wanted to reach.
" ow, with the interdisciplinary program, everything is
consolidated, so all the expenses go toward attracting students to this centralized program. We have cut down on
expenses and decreased duplicated efforts."
"Recruitment involves far more personal contact and
follow-up than before," adds Campagnari. "I attempt to
contact students as soon as I receive any inquiries or GRE
scores and encourage them to fill out an online application."
And while the Internet has certainly helped prospective
students find out about the program, it's interesting to note
that the old-fashioned word of mouth still works wonders.
"About three years ago, we did a mailing to PhD alumni
informing them of what we were doing and how we were
proceeding," Hayden says. "Many of those involved in academic programs have sent us some very qualified candidates.
Our alumni are some of our best recruiters, and we welcome
their recommendations."

Winter

2 00 3

II

If Ill rb J SiC iII

15

��Recently, Paroski agreed to sit down and talk with Buffalo

Physician as part of an ongoing series of conversations with
leaders of UB's School of Medicine and Biomedical Sciences.
(Part I of the interview is published on the pages that follow;
Part II will appear in the spring 2003 issue of the magazine.)

In addition to this conversation-and an earlier conversation
with Dean Michael Bernardino-future issues of Buffalo Physician
will publish interviews with Roseanne Berger, MD, senior associate dean for graduate medical education, and Suzanne Laychock,
PhD, senior associate dean for research and biomedical education, each of whom will be asked about issues pertinent to her
areas of responsibility.
The goal in publishing these articles is to inform our readers
about the complex economic, political, regulatory and historic
considerations school leaders must weigh in making decisions
and to provide a larger context within which to understand the
many new developments taking place on campus.
Comments and questions, as well as suggestions for future
topics, are welcome and can be emailed to bp-notes@buffalo.edu
or mailed to the address printed on the inside front cover of the
magazine, below the heading "Letters to the Editor."
-S. A. Unger, editor

Q: What are the primary challenges you face in leading the three offices
you oversee: medical education, curriculum and admissions?

A: Let's start with admissions, since that is the office I started in
when I first joined the medical school's administration full time.
There, Dr. Bernardino has basically tasked me to do two things:
to give the school a better class every year and to give it a class that
looks more like the community.
In terms of a better class every year, that can be a tough call
because I don't think that the "best class" is necessarily the one
with the highest grade point averages and MCAT scores. While

being bright is certainly a prerequisite for being a doctor, there
are many other characteristics that are important in defining
what makes a good physician; for example, being personable and
professional. So, in the Office of Admissions our primary challenge is to come up with a methodology for finding people who
are capable of excelling in their coursework and who possess

''

critical non-cognitive attributes.
In terms of a class that looks more like the community, we have
a great deal of diversity in Buffalo, Western ew York and throughout the state. For example, we have large African-American and
Hispanic populations. Our current second-year class of 135 students, however, has only six under-represented minority students
in it, which certainly does not reflect the demographics of our
community. So, our challenge is to look for ways to recruit more
students who will not only be competitive, but also make their class
better reflect the community they are going to go out in and serve.
In the Office of Medical Education [OME], our primary challenge is twofold: The first is to serve a registrar function-to track
students and to produce all the paperwork that enables them to
go where they need to go- and secondly, to provide a wide range
of guidance and counseling services for our students.
With regard to the counseling component, we find that every
student who enters our school is truly unique. They all differ
widely in the pressures they experience and how they respond to
them, whether they be academic, financial or personal. Believe
me, these are people who lead widely diverse and exciting lives,
and trying to sort out reasonable solutions to their concerns or
dilemmas takes up a lot of folks' time!
In addition, the students need guidance counseling to help
them to decide what area of medicine to choose. This can be a
very tough decision. Some of the students have a family full of
doctors and they've been exposed to everything, and choosing a
career path is not a problem. For other students, they get to the
end of their third year and they either love or hate everything
and it is truly a crisis for them.
ancy Nielsen, who is the dean for the third and fourth years,
coaches them through this, and Chuck Severin, who is the dean
for the first and second years, helps them through the early years.

W int e r

2 003

l 1ffal1 Pbysicial

17

�Debbie Stamm, who is our assistant dean for student services in OME, spends a lot of time taking care
of the details of daily life that may not be medicinesuch as financial aid, insurance, clubs, summer internships, special events, and so on-but these are the
things that make the medical school experience tick.
Some of our students are married and have children; there are just so many facets of life they need
help integrating.
Again, these may seem like little things, but taken
together, they make the difference between a student
having a good experience or a bad one.
In the curriculum office, our challenge is, obviously, to give the students the education they need to
be good practicing physicians, now and in the future.
To accomplish this, the curriculum needs to be
interesting and stimulating for both the students and
the faculty and it needs to have something on the
menu for all types of learners.
Last year we implemented a new curriculum for
the first and second years. In doing so, we switched
from a discipline-based curriculum to an organ-based
curriculum, where, for example, when you learn the
gastrointestinal system, you learn GI physiology,
pharmacology, anatomy, microbiology, and so on,
because when you go out into the real world and begin
practicing medicine, this is how you will need to put
information together.
When I went to medical school here in the '70s, we
sat through lecture hour after lecture hour-a very
efficient way for the teacher to stuff as much information into your head as possible, but arguably not
the most effective way to learn. Adult learners like to
see the relevance of what they are studying; they like to
apply it, they like to be active learners.
Therefore, in devising the new curriculum, the
goals were to have fewer lecture hours and more
interactive learning sessions and to teach the students
how to go out and find their own information because, again, that's what you do once you get out and
begin practicing medicine.

Q: In recent years, as you have described, the Office of
Medical Education has placed an increased emphasis on
providing services to students, and in 1999 the position of
director of student services was created. Was that a big
change for OME?

A: Yes, it sure was. Actually, when I went through
school here, the staffing and services in OME were

18

I u II all Pb y sic i 11

Wi nt er

2003

fairly generous, but then they went through a period where they
were pretty scant. I think that the staff in the office were very
overextended and it was hard for them to be creative because
they were running to stay in place with the basic mechanics of:
Did the students have grades recorded? Have the dean's letters
gone out? As a result, I think a lot of the quality-of-life issues
got away from them.
Every year the AAMC [Association of American Medical Colleges] has the fourth-year class fill out a graduation survey and
they send the results back to the schools. Again and again, it was
very clear to us at UB that the students felt they received a good
basic education, but that a lot of the support services that made a
difference to people weren't there. The school realized that these
were not things that could be addressed by somebody as a sideline task ten minutes a day. This was a full-time job. In 1998,
therefore, the position of director of student services was created, which was filled by Debbie Stamm. Debbie has done a fantastic job, and the position has assumed such importance that we
recently changed the title to assistant dean for student services.

Q: How is the success of the new curriculum going to be measured, and
when might there begin to be results from these measurements?

A: It's always hard to prove that the way you're doing something is better, particularly when the results are so far down the
line. You know, who makes the best doctor is going to take time
to sort out!
However, in the short term, what we can measure is how they
do on Step 1 of the national boards, the USMLE. Our first class in
the new curriculum is coming through the second year now, so
next summer we're going to know how they did on that. We have
been told, however, that when schools put a new curriculum in
place, they often see a dip in these scores before they see an
improvement, so we are aware of that trend.
For the type of curriculum we've put in place, where you tend to
see the difference is when the students get into their clinical clerkships. Because this year's third-year class is the last class to go
through the old pre-clinical curriculum, we're going to survey the
clerkship directors to get a handle on how well prepared these
students were when they walked in the door. We will be asking
such questions as: Did they seem to be able to integrate the basicscience material? Were they able to think on their feet? How good
were they at going and getting other resources and information
and integrating it? And then we will do this for next year's thirdyear class, which will be the first through the new curriculum, to
see if we have a difference.
Feedback on the success of the new curriculum will be conveyed to the faculty through the appropriate committee structure-for example, the Curriculum Committee, which reports to
the Faculty Council-and through Town Hall meetings.

�Q: Are changes planned for the third and fourth years, as
well? If so, what is the goal of these changes, and what is
the timeline for their implementation?

A: We do have changes planned for the curriculum
in the third and fourth years, but they are not quite
as sweeping.
Our goal is to put some elective time into the third
year for career exploration. For the students, choosing the direction they will take after graduation is a
very pressured decision, and so we want to provide
them with a bigger sampling of career options in their
third year.
Currently, the third-year students have seven-week
clerkships in family medicine, psychiatry, OB-GYN
and pediatrics and eight-week clerkships in internal
medicine and surgery. We are proposing reorganizing
the clerkships into four 12-week blocks. One 12-week
block would have six weeks of OB-GYN and six weeks
of pediatrics; another would have six weeks of family
medicine and six weeks of psychiatry. The remaining
blocks would be eight weeks of internal medicine or
surgery, combined with four weeks of elective time.
The four weeks during medicine could be used for
any type of elective, and the four weeks during surgery
will be used for the advanced-surgery elective previously required in the fourth year.
This clerkship design will reduce the number of
students per clerkship because, at any given time,
approximately 25 students will be taking an elective.
This will relieve some of the congestion on the inpatient services and in the clinics. We also plan to give all
third-year students two weeks off at at the end of
December and over New Year's, as students want to be
home with their families during the holidays and the
combination of cancelled clinics, few elective surgeries and a decreased inpatient census makes these
two weeks a difficult time to teach.
We are also proposing that the third year of medical school start earlier than we currently do- in early
July rather than mid-August. One of the advantages
of starting earlier is that it gives the students more
time when they get to their senior year to either take
additional electives in things they think they may
want to do, or to get things out of the way to give them
time to travel when they're on the interview circuit
for residency positions.
With regard to the timeline for these changes, we
propose to partially implement them in 2003 and fully

implement them in 2004. We need to phase in the
earlier start date for third year to avoid overlap between the incoming and outgoing third-year class and
to allow students adequate notice to adjust summer
plans and financial aid. We also want to make sure we
have faculty buy-in regarding the proposed changes.

Q: What is the "continuity series"

being developed for

third- and fourth-year students, and what is its purpose?

A: The continuity series-so called because it will
span all 48 weeks of those clerkships we just discussed-is something we are putting in place for two
reasons: The first is to keep the third- and fourth-year
students connected to the school once they begin their
rotations in the hospitals. We have a very decentralized clinical campus; one class can be placed in up to
nine different hospitals. Given these logistics, they can
lose touch with each other and the school's faculty.
This is tough on the class and can be very alienating. It
can also make it difficult to provide the students with
the counseling they need.
So, to that end, the continuity series will bring the
students back on campus a couple of times a month in
the evenings and will give us an opportunity to talk
with them about all the housekeeping details that need
to be covered and to keep them connected to one
another and to the school.
The second reason for starting the series is to provide a forum for introducing the students to topics
that don't belong in any one place in the curriculum,
but that belong everywhere.
These 'orphan topics' can include ethics, professionalism, and some basic-science integration, as well
as topics that are suddenly in vogue-for example,
bioterrorism. Do you put that in obstetrics or pediatrics? Obviously, it doesn't really fit a particular clerkship. And yet, would you in this era graduate someone
from medical school who hadn't been introduced to
this topic? o, you wouldn't.
So this is the continuity series, and we are piloting
it in a limited fashion this year, from 6:00 to 8:00 in the
CD
evening on some Tuesdays.
Editor's note: Part II of this conversation, which will be published in the
spring 2003 issue of Buffalo Physician, will include in-depth discussion
of admissions procedures and criteria, minority recruitment efforts and
the role scholarships play in attracting quality students.

Winter

2003

l11fal1 Hysiciu

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�MEDICAL

SCHOOL

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Honors Convocation
Recognizing medical students' achievements

HE ANNUAL Ho ORS CoNVOCATION

recognizing academic excellence

among first- and second-year students at the University at Buffalo
School of Medicine and Biomedical Sciences was held in Butler
Auditorium on September 21, 2002.
The following is a list of award recipients and a description of
the awards received.

Departmental Awards
The departments in the School of Medicine
and Biomedical Sciences have established
awards to recognize meritorious performance
in their courses as well as outstandingachievement in other curriculum-related activities.

Garron Solomon, '04, has
received the Department
of Microbiology's Ernest
Witebsky Award for Proficiency in Microbiology,
which is given to the secondyear student achieving the
highest grade in the microGARRO'I SOLOMO"
biology and immunology
course. Dr. Witebsky was the founding
chair of the Department of Microbiology.

Primary Care Summer Externship Program. Dr. Calkins is a former chair of the
Department of Medicine.

Natalie Shaw, '04,
received the Department of Patholo gy's Kornel Terplan
Award, presented to
the student with the
highest combined
average in the two
second-year pathology courses. Dr. Terplan was a past chair
of the department.
Shaw also received an Association of
Pathology Chairs Honor Society Award.

Carmine Grieco, '04,
David Block, '04, received the Department

D A\' 1[)

20

of Microbiology's Marek Zaleski Award,
which is presented to the
student who best combines
high standards of academic
achievement with outstandingservice to the community.
The second-year class chooses
the recipient.
Block also received the
BLO&lt; K
Evan Calkins Primary Care
Achievement Award, which
is given to one outstanding student in the

laffall nysiciaa

W ir1t er

2003

received the Department of Pathology's
John Sheffer Award,
which is given to the
second-year student
who has performed
at the highest level in
CAR\11 "1E GR IECO
the laboratory portion of the courses in general and systemic
pathology. Dr. John Sheffer practiced pathology in Buffalo for over 35 years and
was acting chair of the Department of
Pathology from 1972 to 1974.

Julie Baker, '04, received
The Department of Pathology's American Society of
Clinical Pathologists Award
for Academic Excellence, J u LIE B AKER
which is presented to the
second-year student who has demonstrated high academic achievement and outstanding performance in the pathology
laboratory.
Jennifer Nelson '04, received the Department of Pharmacology and Toxicology's
Edward A. Carr, Jr. Clinical
Pharmacology Award and
the Douglas S. Riggs Award.
The former award is given
to the student achieving the
highest average in the Fundamentals of Pharmacology
course. Drs. Carr and Riggs
were chairs of the Department of Pharmacology and
Toxicology.
elson also received an Association of
Pathology Chairs Honor Society Award.

Other Awards
Neeta Chaudhary, James Hereth, Jason
Hoffman, Jennifer Maclaughlin, and
Eric Ko, Class of 2004, received the
AstraZeneka Cardiovascular Drug Monograph Award, which is presented to
second-year students by the Department
of Pharmacology and Toxicology. They
are based on the quality of a monograph
written in the form of a package insert.

�)EFFREY FEI!'&lt;ER

MATTHEW fERNAAYS

Jeffrey Feiner and Matthew Fernaays,
Class of 2005, received the McGraw-HillLA GE Medical Student Award, which is
given to the two highest-ranking students
in the first-year curriculum.

Discipline Honorary Societies
The Association ofPathologyChairs Honor
Society awardees were Carmine Grieco,

Sandy Kotiah, Jennifer Nelson, Jennifer
Nowobiliski, Natalie Shaw, Class of2004.

ELIZABETH BOURKE

LISA ESLER

]AMES W. BOYLE

DAVID

LAURA CINSKI
DANIELLE
DORSANEO

Ft

ToDD ]ANICKI

LY:--&lt;OSAY

]ENNIFER KORZEN

WILLMOTT-

MELANIE FIORELLA

TIMOTHY PARDEE

BARTOS

BRYAN GARGANO

ERIC SCHAEFER

DOROTHY

STEPHEN

LISA ANN DOS

TAK

HENDRICKS

JoYcE ZMt:DA

TURKOVICH

SANTOS

CD
Dean's Letters of Commendation
Years 1, 2 and 3
Dean's Letters of Commendation recognize exceptional coursework. In years one and two, they are awarded to students who earn
honors grades in 75 percent of required courses or achieve 75 percent of available honors points each year. In year three, students
who earn at least four honors and two high satisfactory grades are honored.
Year One

GLENN MILLER

MATTHEW ABOUDARA

MICHAEL NAZARETH

KRISTINE ALGOE

RYAN

Ross BAUER

CHADD

SARA BROOKSSIENKIEWICZ

CHRISTOPHER
BRENNAN

SHERIN HUSSAIN

KAVITA

MICHAEL jORDAN

TIMOTHY O'HERRON

YALAKONDA

LAURA Clt-&lt;SKI
MICHELLE CLARK

A:-.'

LORI BRODERICK

MANAS! KADAM

KIMBERLY CARNEY

JosEPH

]AY PAHADE

CATHERINE CASEY

ERIC Ko

DIANA PRATT

EsME Ft:--&lt;LAY

KRISTOPHER PAOLINO

LEE CHALUPKA

SANDY D. KOTIAH

MARAT REYZELMAN

DAVID FI:-&lt;TAK
ALFRED FRO:-.JTERA

ELSON
ESBIT

EETA CHACDHARY

KtTA

jESSICA PELOW

LISA

]ASON PERICAK

LtsA EsLER

DOS SA:--&lt;TOS

ROBERT BUCELLI

RoNALD PARSONS

CRISTINA LAMPURI

KARl SCANTLEBLRY

MARK BuRKER

BETH PETERSON

REBECCA CHUSID

MARY LEUNG

ELIZABETH ScHNEIDER

BRYAN GAR(,ANO

SAMANTHA CHEN

KEVIN SHILEY

SHAWN CIECKO

DEANNA LoVALLO

CORINE SEBAST

}ULIF G.&gt;.\ IN

} EFFREY FEINER

KEITH SIKORA

DAVID CIPOLLA

}ENNIFER

MATTHEW FERNAAYS

DALJIT SINGH

GREGORY CONNOLLY

ALLISON GRAZIADEI

jOANNE SMITH

SARA CONNOLLY

ICOLE MANN

ATALIE SHAW

MACLAUGHLIN

ICHOLAS 51 LV ESTRI
GARRON SoLOMON

CHRIST"A GRACZYK
DoROTHY HENDRicKs
5TEPHEK HESS

THOMAS GRt-BER

HoUMAN VosoGHI

)EFFREY DAYTON

TANIA MARIANI

ERIK STEINIGER

Tooo ]ANICKI

CRAIG HENDLER

DAVID WAGNER

ANNE DELLES

}EFFREY MARTINEZ

KEVAN STERNBERG

SARA KAPROVE

}ACQUELINE }ULIUS

STEVEN WATSON

}F. 'NIFER KoRnN

FAYE ]USTICIA-LINDE

THOMAS DUQUIN

MEGAN MOORE

]AMES SULZER

ANDREW FABIANO

BRITTANY MORSE

}ILL THOMAN

K1&gt;1BERELY LEONARD

CAREN GELLIN

EvE MoscATO

MEGAN TRACY

MICHELE 0BROBINA

MICHAEL WEII\GARTEN • STEPHEN TL'RKO\'ICH

)OHN KARPIE

Year Two

SAFINA KoREISHI

MEGHAN ANDREWS

BRIAN GIORDANO

)OLENE MusCAT

AMANDA KOST

CATHERINE ARTMAN

CARMINE GRIECO

SYED MusTAFA

MICHAEL LADRIGAN

DANIEL BAER

)ASON GuTMAN

}ENNIFER

MONICA LEE

)ASON BARKER

CHRISTINA

)AMES NITZKORSKI

ELIZABETH BoL•RKE

ANDREA LUCZKOWSKI

)A,1ES R. BOYLE

)ENNIFER LYNN

)AMES W. BOYLE

SAMUEL McCABE

HAVERSTOCK

ELSON

}ENNIFER WILER

Year Three

Ln..:DSAY WILLMOTT BARTOS
)OYCE Z.\1l DA

OWOBILISKI

W i 11t e r

2 00 3

1 111111 Hysici11

21

�MEDICAL

SCHOOL

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Sung Scholars Named

M oLLY M ooRE

H ANG K YU P ARK

Molly Moore and Hang Kyu Park, Class of2006, are the recipients of this year's John J. and
Janet H. Sung Scholarship.
Moore, a native ofHamburg, ew York, earned a bachelor of arts degree in biomedical
sciences from University at Buffalo.
"I wish to express my sincere gratitude to Dr. Sung and Mr. Sung, and I'm honored to
be a recipient of their generous gift," says Moore.
Park, who was born in Korea and immigrated to the United States in 1994, earned a
bachelor of science degree in chemistry from Queens College, CUNY.
"I am fortunate to be accepted to UB's medical school," says Park. "Furthermore, I am
very honored to be recognized as a Sung scholar. This scholarship enhances and enriches
my educational experience at UB and encourages and assists me to be successful academically. I have had the chance to meet many helpful and wonderful people because of the
Sung scholarship."
The Sung Scholarship is funded by a $1 million gift to the University at Buffalo School
of Medicine and Biomedical Sciences by John and Janet Sung, who came to the United
States from Korea in 1972 with only $200 to complete their education. At the time, they had
two dreams: to attain their educational goals and to establish a renowned clinic in radiology,
both of which have been realized.

Medical Alumni Association Scholarship
Lori-Ann Oliver and Jodi-Ann Oliver, Class of 2006, are recipients of this year's Medical Alumni
Association Scholarship. The scholarship is made possible by the generosity of the alumni through
their reunion gifts designated to the Medical Association endowment fund.
Recipients are selected by the admissions committee according to considerations of financial
need and academic merit based on the incoming students' applications.
The Olivers, twin sisters, were born in Jamaica and raised in Queens, ew York. They attended
Cornell University and earned bachelor of arts degrees in English in 2001.
4D
- S. A . UNGER

2 2

11flal1 Hysiciao

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2003

�Thomas J. Lawley, MD, an internationally known expert in autoimmune skin disease and Dean and William P. Timmie
Professor of Dermatology at Emory University School of Medicine, is the recipient ofthe University at Buffalo's 2002
Distinguished Medical Alumnus Award.
Lawley was presented the award on September 19,2002, by Patricia Duffner, MD '72, president of the UB Medical
Alumni Association, at a dinner held at the Buffalo Club.

fter graduating with honors from
UB's school of medicine in 1972,
Lawley trained in dermatology at
Yale University School of Medicine, UB and the National Institutes of Health (NIH).
Following completion of his
training, he stayed on at the NIH,
where he rose to the rank of senior investigator in the Dermatology Branch of the
National Cancer Institute(NCI).
In 1988, Lawley left the CI/NIH to
become chair of the Department of Dermatology at Emory University School of
Medicine. Under his leadership, the faculty grew six-fold and the department
went from having no NIH funding to
becoming the third highest NIH-funded
department in the country. Lawley, whose
research interests include the cell biology
of endothelial cells and the regulation of
cell adhesion molecules and inflammation, has published more than 150 original
articles and book chapters.
In 1996, Lawley was appointed dean of
the Emory University School of Medicine,
having served the previous year as interim
dean and executive associate dean. In this
role, he has focused on creating and implementing two critical strategic plans. Under
the research plan, he has recruited more
than 80 new scientists and has fostered the
establishment of several interdisciplinary
centers. He has also established the Dean's
Scholar Program, which protects the research time of clinician scientists and

Distinguished Medical Alumnus Thomas J. Lawley, MD '72, left, being congratulated for his outstanding contributions
to research and education by Patricia Duffner, MD '72, right, president of the Medical Alumni Association.

fulfills all 25 goals outlined by his comprehensive plan. During Lawley's tenure as
dean, the amount of research space in the
Emory University School of Medicine has
doubled and the amount of research funding increased by 150 percent.
Under the teaching plan, Lawley has
increased scholarships, created the Dean's
Teaching Awards, expanded the MD/PhD
Program and developed plans for a new
Medical Education Building.
In addition to spearheading these strategic initiatives, Lawley takes a proactive
role in overseeing the clinical enterprise at
Emory and its affiliated sites and has continued to see patients on a regular basis.
As a result of these and other initiatives,
the Emory School of Medicine has risen

dramatically in rankings to become one of
the outstanding medical schools in the
nation since Lawley assumed the role of
dean in 1996.
Over the years, in addition to his academic responsibilities, Lawley has served
on many national boards and committees,
including NIH study sections and the
National Advisory Allergy and Infectious
Diseases Council for the National Institute
of Allergy and Infectious Diseases of the
NIH. He is president of the Emory Medical Care Foundation and chair of the
board of directors of the Emory Children's Center. He also serves on the board
of directors of the Emory Clinic, Emory
Healthcare, and the Emory Children's
CD
Research Center. -S. A. UNGER

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2003

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�PATHWAYS

NEws ABOUT UB's ScHOOL OF MEDICINE
AND BIOMEDICAL SciENCEs AND ITS
ALUMNI, fACULTY, STUDENTS AND STAFF

Velazquez Named
Interim Chair

VELAZQUEZ

24

laffa le H ys ic i aa

Mallory Institute of Pathology and Boston University
Medical Center in Boston,
Massachusetts. Velazquez
is board certified in clinical
pathology and is currently
enrolled in the Master's in
Health Care Administration and Policy Program
at Harvard University.

Francisco Velazquez, MD, has
been named interim chai r of
the Department of Pathology
and Anatom ical Sciences in
the University at Buffalo
School of Medicine and
Biomedical Sciences.
Velazquez has held
-S. A. UNGER
the rank of clinical
associate professor
since August 2000
Robotic Surgery
Specialist
and has also served
as pathologist-in-chief
Celeste M. Hollands, MD, a
at Kaleida Health.
pioneer in pediatric robotic
Recently, he was
surgery, joined Children's
appointed division
Hospital of Buffalo in
commissioner for Western
September 2002 as clinical
New York for the College
director of the
of American Pathologists'
Miniature Access
Laboratory Accreditation
Surgery Center
Program.
(MASC) and
Velazquez has held
the Miniature
academic appointments
Access Teaching,
at Boston University
Training and
School of Medicine and
Robotic Research
H OLLANDS
Wayne State University
Center (MASTin Michigan. He received
TARR), located at the Unihis medical degree from
versity at Buffalo School of
Universidad Central del
Medicine and Biomedical
Caribe, Puerto Rico, and
Sciences. Hollands, who has
served his residency at the
also been named associate

Wznter

2003

professor of surgery and
pediatrics at UB, debuted
robotic surgery at the MASC
on September 27, 2002, when
she operated on two children
using this new technology.
The procedure was telecast
live to UB's School of
Medicine and Biomedical
Sciences, where twenty-four
pediatric surgeons-in-training
from various institutions
throughout orth America
viewed it as part of a two-day
advanced training course in
pediatric surgery hosted by
UB, CHOB, the MASC and
the MASTT ARR.
"We are very fortunate to
have Dr. Hollands as a
member of the Children's
Hospital staff and the UB
medical faculty," says Philip
L. Glick, MD, surgeon-inchief at CHOB and professor
and interim chair of surgery
at UB. "She is one of the few
pediatric surgeons in the
world to work extensively
with robotics. Her work is
ground breaking."
Hollands earned her
medical degree at the

�University of South Alabama
researchers
College of Medicine. She
in science,
completed her general
medicine and
surgery training at the
engineering
Graduate Hospital of the
honored at a
University of Pennsylvania
special dinner
and her pediatric surgery
held last
training at Miami Children's
October in
TREY! SAN
Hospital. Her research
Albany.
interests include pediatric
Trevisan is interim dean of
trauma and surgical educathe School of Health Related
tion in addition to miniature
Professions and professor and
access surgery, robotics and
chair of the Department of
new technologies as they
Social and Preventive
apply to these fields.
Medicine (SPM) in the UB
"The work we will be
School of Medicine and
doing here at Children's will
Biomedical Sciences. A UB
faculty member since 1985,
be paving the way for other
types of robotic surgeries,"
he is director of the Center for
says Hollands. "Eventually,
Preventive Medicine-part of
we will find ways to use this
the Women's Health Initiative-as well as SPM chair.
technology to help very tiny
He has served as interim dean
infants and possibly even for
of the School of Health
surgery in the womb. I am
very excited about the
Related Professions since
prospect of finding new and
September 1, 2001, and in
better ways to perform
that capacity is spearheading
surgery on infants."
an effort to create a School of
The two-day training
Public Health and Health
program was sponsored by
Professions at UB.
Ethicon Endo-Surgery, Inc.,
A prolific researcher,
Stryker Corporation, ComTrevisan has authored or
puter Motion, Inc., Berchtold, co-authored more than 110
B-K Medical Corporation,
articles in scholarly publications
and LSI Solutions.
and delivered numerous
- S. A. UNGER
presentations at national and
international meetings. A
recipient of grants from such
Trevisan Receives
Chancellors' Award
funding entities as the
ational Institutes of Health,
Maurizio Trevisan, MD, was
the American Heart Associaone of three University at
tion and the ational Cancer
Buffalo faculty members
Institute,
his current work is
selected to receive Chanfocused
on
cardiovascular
cellor's Research Recognition
disease
epidemiology.
Awards for 2002 and was
among leading SU Y

- SuE WuETCHER

Kaiser Named Interim
CEOatECMC

The Erie County Medical
Center (ECMC) Board of
Managers has appointed
Roger E. Kaiser Jr., MD '79,
interim CEO of the ECMC
Health care
Network.
Kaiser, who is
an associate
professor
of clinical
anesthesiology in UB's
School of
KAISER
Medicine and
Biomedical Sciences, currently
serves as ECMC's medical
director, as well as clinical
director of its Department of
Anesthesiology.
Kaiser agreed to fill the
pos1t1on in ovember 2002
while the ECMC Board of
Managers completes its search
for a permanent CEO to
replace Sheila K. Kee, who
stepped down from this role
on October 31, 2002.
-S.

A. UNGER

Book on Children's
Mental Health

David Kaye, MD, associate
professor of clinical psychiatry, and Maureen Montgomery, MD,
assistant
professor of
clinical
pediatrics at
the University
at Buffalo,
have authored
KAYE
a text titled

W i nte r

the Handbook of Child and
Adolescent Mental Health,
along with Stephen Munson,
MD, associate professor of
psychiatry and pediatrics at
the University of Rochester.
Published in October 2002
by Lippincott, Williams and
Wilkins as part of its "Core
Handbooks in Pediatrics"
series, the book is intended to
be a practical, handson guide for primary
care physicians. Its
authors took
special care to
integrate the
perspectives of
both mental
health
professionals
and pediatricians, explains
Kaye, who adds that the
book fills a niche in an area of
increasing importance in
health care.
"There are large numbers
of children and adolescents
with mental health problems
presenting to primary care
physicians, and yet there is no
single source of treatment
information available to guide
the practitioner on the front
lines," he says. "Pediatricians
are increasingly asked to
prescribe psychotropic
medications, and we hope this
book will help them make
more informed decisions."
In addition to addressing
common mental health
problems seen frequently in
practice, the book explains
the various systems involved

20 0 3

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�PATHWAYS

in children's mental health
(i.e., school, social services,
the legal system, the mental
health system ). By blending
the perspectives of child
psychiatry and general
pediatrics, "the authors
present a pragmatic and
current approach to issues
of office evaluation, assessment, and treatment,
including pediatric psychopharmacology," according to the publisher.
- S. A .

U N G ER

.lames Waxmonsky
.loins Psychiatry

from Cornell University in
1992 and a medical degree,
James G. Waxmonsky, MD,
summa cum laude, from UB in
joined the University
1996. He completed
at Buffalo School of
residency training in
Medicine and
adult psychiatry in the
Biomedical Sciences
UB Medical-Dental
in September 2002 as
Consortium in 1999.
assistant professor of
Following residency
psychiatry. He is
training, he comaffiliated with the
pleted a fellowship in
Children's Hospital
WAXMONSKY
child and adolescent
of Buffalo, where he
psychiatry at
serves as the primary psychiaMassachusetts General
trist in the Outpatient
Hospital (MGH) and a
Behavioral Health Unit.
psychopharmacology research
Waxmonsky earned a
fellowship, led by Dr. Joseph
bachelor of science degree
Biederman, also at MGH.

Waxmonsky's primary
research interests include the
pharmacological treatment of
children with bipolar disorder
and attention-deficithyperactivity disorder
(ADHD) and treatment of
adolescent addictions, as well
as adults with ADHD.
- S. A . UN G ER

Ferrick .loins
Orthopaedics

Michael Ferrick, MD, has
joined the pediatric orthopaedic surgery staff at the
Children's Hospital of Buffalo
and has been appointed

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2003

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�clinical assistant
professor of
orthopaedics at
the University at
Buffalo School of
Medicine and
Biomedical
Sciences.
FERRICK
A Buffalo
native, Ferrick graduated,
summa cum laude, from the
University of otre Dame in
1987. He earned a medical
degree from the University of
Michigan in 1992, after which
he returned to Buffalo for
residency training in orthopaedic surgery.

From 1997 to 2001 Ferrick
served as an active-duty
orthopaedic surgeon in the
United States Army, and in
2002 he completed a fellowship in pediatric orthopaedics
and scoliosis at the Texas
Scottish Rite Hospital for
Children in Dallas, Texas.
Ferrick's research and
clinical interests include
pediatric spinal deformity and
childhood lower-extremity
disorders.
- S. A.

UNG ER

Stamm Named
Assistant Dean

Debra L. Stamm has been
promoted to assistant dean
for student services in the
Office of Medical Education
(OME) in University at
Buffalo's School of Medicine
and Biomedical Sciences. She
previously
served for
three years
as director
of student
services in
OME. In her
new position, Stamm
STAMM

continues to advocate for
students and to act as a liaison
between the student body and
the school's administration.
She also serves as a resource
person for student clubs and
organizations recognized by
Polity, coordinates summer
programs for students and
assists with the implementation of MedCAREERS, a fouryear career planning program
created by the Association of
American Medical Colleges
to help medical students
select a specialty.
Stamm earned a bachelor
of arts degree in psychology at

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l 1ffal1 Pbysicia1

2 7

�PATHWAYS

the State University of ew
York at Genesee in 1992 and
a master of education degree
in college counseling and
student personnel administration at UB in 1995. Prior
to joining the staff in OME
in September 1999, she was
admissions coordinator in
the Offices of Admission
and Financial Aid at Harvard
Medical School in Boston,
Massachusetts.
-S. A.

UNGER

Chief of Thoracic
Surgery at RPCI

Todd Demmy, MD, has been
named chief of the Thoracic
Surgery Division at Roswell
Park Cancer
Institute (RPCI)
and associate
professor of
surgery at the
University at
Buffalo School of
Medicine and
Biomedical
DEMMY
Sciences.
Demmy comes to Buffalo
from the University of
Missouri Hospital and
Clinics, Columbia, MO,
where he served as chief of
thoracic oncology, associate
professor of surgery in the
Division of Surgical Oncology
and Cardiothoracic Surgery
and co-director of the
Cardiac Transplant Program.
He earned his medical degree
at Jefferson Medical College,
Philadelphia, PA, in 1983,
and completed residency
training in general surgery

28

llffal1 Hysiciaa

(1988) at Baylor College of
Medicine, Houston, TX, and
in cardiothoracic and cardiovascular surgery (1991) at
Allegheny General Hospital,
Pittsburgh, PA.
Demmy is a Diplomate of
the American Board of
Thoracic Surgery and the
American Board of Surgery.
Although he has had laboratory and human research
projects in both heart and
lung surgery, he is joining
RPCI to focus his efforts on
thoracic oncology. His
research interests include the
minimally invasive management of tumors of the lung,
esophagus and central portion
of the chest.
- DEBORAH PETTIBONE

Kuvshinoff .Joins
Surgery at RPCI

Boris W. Kuvshinoffll, MD,
has joined the Division of
Gastrointestinal Surgery at
Roswell Park Cancer Institute and has been named
assistant professor of surgery
at the University at Buffalo
School of Medicine and
Biomedical Sciences.
Kuvshinoff comes to
Buffalo from the Ellis Fischel
Cancer Center, Columbia,
MO, where
he served as
chief of the
Section of
Hepatobiliary
and Pancreas
Tumors,
Division of
Surgical
KuvSHINOFf

Wr11t er

2 00 3

Oncology, and interim chief
in the Division of Surgical
Oncology, Department of
Surgery, at the University of
Missouri HealthCare. He
earned his medical degree
from the University of
Maryland (1986) and
completed residency training
in the Department of Surgery
(1993) University of Cincinnati Hospital and a fellowship
in Surgical Oncology (1995)
at Memorial Sloan-Kettering
Cancer Center.
Kuvshinoff is boardcertified in general surgery
(1995) by the American Board
of Surgery. His research
interests include radiofrequency ablation of primary
and secondary liver tumors
and neoadjuvant therapy with
sphincter-sparing surgery for
low-lying rectal cancers and
the surgical treatment of
hepatobiliary and pancreatic
malignancies.
- DEBORAH PETTIBONE

Ciovino Receives
Doii/Wynder Award

Gary Giovino, PhD, a tobacco
control specialist in the
Department of Cancer
Prevention, Epidemiology
and Biostatistics at Roswell
Park Cancer Institute and a
research professor in University at Buffalo's Department
of Social and Preventive
Medicine, received the Doll/
Wynder Award during the
2002 annual meeting of the
Society for Research on
icotine and Tobacco

(SRNT) in
Savannah,
Georgia.
Giovino is
only the
second
winner of
this prestiGIOVINO
gious award,
which is presented every three
years. The award honors
scientists who have made
ground breaking advances in
public health, public policy or
epidemiological research,
focused on tobacco use and
the consequences of smoking
on populations of smokers.
The award is named after Sir
Richard Doll and Dr. Ernst
Wynder, whose influential
research in the 1950s clearly
established the link between
smoking and lung cancer.
Giovino is recognized
internationally for his
contributions to the measurement of tobacco use. In April
2002, he received a four-year
grant of approximately $3.5
million from the Robert
Wood Johnson Foundation
to conduct a comprehensive
survey to assess youth
smoking cessation needs
and practices.
- DEBORAH

PET T IBONE

O'Connor and Fakih
.Join Medicine

Two medical oncologists
have received joint appointments to Roswell Park
Cancer Institute (RPCI) and
to the University at Buffalo
School of Medicine and

�Biomedical Sciences,
where they have been
named assistant professors
of medicine.
Tracey L. O'Conner,
MD '97, will serve in the
Breast Cancer Division at
RPCI, and
Marwan G.
Fakih, MD, in the
Gastrointestinal
Cancer Division.
After earning
her medical degree from UB in
O'CONNER
1997, O'Conner
completed residency training
in internal medicine at Strong

.,

"""

,.,,

Memorial Hospital, University of Rochester Medical
Center, in 2000 and a
fellowship in medical
oncology at RPCI in 2001.
She is board certified in
internal medicine by the
American Board of Internal
Medicine and is a member of
the American Association of
Cancer Research and Alpha
Omega Alpha Honor Medical
Society. Her research interests
focus on novel treatments for
breast cancer and supportive
care therapies for patients
with advanced disease.
Fakih comes to Buffalo

from the University of
Pittsburgh School of Medicine, where he served as
assistant professor of medicine. He earned his medical
degree at the American
University of Beirut, Lebanon,
in 1992 and completed
residency training in internal
medicine at
Wayne State
University in
1995 and a
fellowship in
hematology
and oncology at the
University of
FAKIH

Pittsburgh in 2001. He is
board certified in internal
medicine and medical
oncology by the American
Board of Internal Medicine,
and is a member of the
American College of Physicians, the American Society
of Hematology, the American
Society of Clinical Oncology
and the European Society of
Medical Oncology. His
research interests include the
development of novel
treatments for patients with
gastrointestinal malignancies.
- DEB O RAH PETTIB O NE

GENESEE
HEARING SERVICES

THE AUDIOLOGY
CENTER

61 Wehrle Drive
(Near Harlem)
Amherst 14225

630 Orchard Park Rd.
(Near Ridge Rd.)
West Seneca 14224

837-6213

712-2000

• Diagnostic audiometric evaluations (pediatric and adult)
• Digital &amp; programmable hearing aid fittings on 60 day trial basis • Tinnitus evaluation and therapy
• Vestibular evaluation for patients with dizziness/vertigo • Vestibular therapy • State of the art facilities

"The Ear is the Road
to the Heart"
( Voltai re)

Daniel Schneider, AuD

Jennifer Schneider, MA

Win t er

Jerri Kaplan Joyce, MA

2003

111111 1 Pbysicill

29

�PATHWAYS

Western New York Pioneers of Science
The inaugural Western ew York Pioneers of Science Educational Conference and Awards
Banquet, sponsored by the Hauptman-Woodward Medical Research Institute, was held on
October 30, 2002. The purpose of the awards is to focus public awareness on the many
significant scientific advancements that have been developed in our region and to recognize those individuals who have achieved prominence through their discoveries. Among
those honored at this event were the following members of University at Buffalo's medicalscientific community and affiliated institutions:
T. MingChu, PhD, DSc, a research professor at Roswell Park Cancer Institute,

developed the PSA (prostate specific antigen) test, which has revolutionized the
detection of prostate cancer and become the world standard for early detection.
Chu received postdoctoral training at Hauptman-Woodward Medical Research
Institute, University at Buffalo and Buffalo General Hospital. Currently, he is
engaged in research that focuses on the immunodiagnosis of pancreatic cancer.

John A. Edwards, University at
Buffalo professor emeritus of
medicine and founder of the
Alzheimer's Disease Assistance
Center of Western New York, died
October 28, 2002, in Sisters
Hospital. He was 66.
Edwards, who retired from UB
in 2000, had been acting head of
the Division of Geriatrics/
Gerontology in the School of
Medicine and Biomedical Sciences.

Dr. Wilson Greatbatch is known for inventing the implantable cardiac

pacemaker and for introducing the long-life lithium iodine battery into
medical usage. He has dedicated his life to studying interdisciplinary areas
combining engineering with medical electronics, agricultural genetics and
the electrochemistry of pacemaker batteries. He is currently adjunct
professor of electrical engineering at the University at Buffalo.
Herbert A. Hauptman, PhD, a world-renowned mathematician, received the

obel Prize in Chemistry in 1985 for a mathematical formula known as
direct methods. His work changed the field of chemistry and began a new
era in molecular structure determination of crystallized materials. He is
currently president of Hauptman-Woodward Medical Research Institute
and a UB Distinguished Professor in the Department of Structural Biology.

Anative of Hawarden, Wales,
Edwards obtained medical degrees
from the University of Liverpool in
the United Kingdom in 1959 and
trained in internal medicine in the
U.K. He came to Buffalo in 1967 and
completed atwo·year fellowship in
medical genetics at the University
at Buffalo School of Medicine and
Biomedical Sciences. He joined the
UB faculty as aresearch assistant
professor of medicine in 1969.
Edwards received aNational
Institutes of Health Research
Career Development Award and
was a member of the American

Posthumously
Lawrence D. Jacobs, MD, was chair of University at Buffalo's Department of

Society of Clinical Investigators,

eurology and head of the Jacobs eurological Institute at Buffalo General
Hospital, which is affiliated with UB. A dedicated physician-scientist, he
was world renowned for groundbreaking research on multiple sclerosis and
for the development of new treatments for this disease.

the American Foundation for
Clinical Research and the New York
Academy of Sciences.
He was medical director of the
Episcopal Church Home Long Term
Care Facilities and Adult Day
Program, and was a member of the
Episcopal Church Homes board. He
also was president of the Amherst
Senior Center advisory board.

30

l ufllil Pbpitill

W i n ter

2003

�New Web Index to the Buffalo MedicalJourna1(1845-1919)
The Buffalo Medical Journal, published from

hospitals and discoveries,

1845 through 1919, contains original submis-

• contain obituaries and biographies about

Education Services, and linda Lohr, manager of

Sharon Gray, former head of Reference and

sions by Buffalo and Western New York physi-

Western New York physicians and nurses

the Robert L. Brown History of Medicine Col-

cians, including case studies, editorials and

• chronicle the UB medical school and regional

lection in the Health Sciences library, Jed the

articles, as well as reprints of articles published

medical history.

in other American and foreign medical journals
of the time.

project and established criteria for articles. Un-

Also included are select editorials by Buffalo

der the direction of Corinne Jorgensen, PhD,

Medical Journal editors. (The first editor of the

students in the UB Department of library and

Because indexing for this publication was

journal was Austin Flint, MD, a founding faculty

Information Studies completed half of the in-

inconsistent and sporadic, a comprehensive in-

member of the then-University of Buffalo School

dexing (nearly 1,200 articles).

dex in a single, searchable site on the web has

of Medicine. A professor of medicine as well as

Funding for the project was provided by the

recenUy been compiled, increasing access to the

the medical school's first registrar and treasur-

Friends of the Health Sciences library and the

journal's unique information for those interested

er, Flint edited the journal from 1845 to 1855.)

Western New York library Resources Council.

in the medical history of Western New York.
The database includes articles that:

The indexing project was a collaborative

Mouse Calls is compiled by Pamela M. Rose,

effort between the UB Health Sciences library,

MLS, Health Sciences Library, University at Buf-

• are written by Western New York physicians

the UB Department of library and Information

falo, 3435 Main St., Buffalo, NY 14214, (716}

• describe Western New York heaHh issues,

Studies, and the UB University libraries.

829-3900, ext 129; prose@acsu.buffalo.edu. ' ·

Chofce
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1111111 Pbysiciae

31

�era
otential outcomes for the newly christened post- The Structure of Proteins
genomic era have been widely prophesized and pub- At the UB Center of Excellence in Bioinformatics, one aspect of
licized: The development of drugs targeted to an research focuses on predicting the structure of proteins of a
individual's genetic profile. The elucidation of ways certain size-below a couple of hundred amino acids-and
all biochemical processes interact in the human body. figuring out how they fit into the extremely complex biology of
The creation of precise methods of diagnosing condi- both normal function and disease.
tions and treating them with minimal side effects.
"Ultimately, we' re trying to reduce the lead time for drug
Key to translating these theoretical potentials into development, not for one molecule or a few, but for hundreds
concrete results is the relatively young science of bio- or even thousands," Skolnick explains.
informatics and the ability ofbioinformaticians to acWithout the power of the CCR's supercomputers, this recess and leverage the exponential power of supercomputers.
search would not be capable of fulfilling its cutting-edge
At the University at Buffalo's Center of Excellence in Biopotential. "Even if each simulation of each protein took
informatics, director Jeffrey Skolnick, PhD, UB Distinfive days of computer time, and even if you're looking
guished Professor, and his research team have access to
BY
at just 14,000 protein structures (the small proteins in
ELLEN
this indispensable computing power and are focusing all
the human genome), then you're talking about 70,000
GOLDBAUM
their efforts on leveraging it to its maximum capability.
days to predict protein structure on a single computer
In fact, when describing computing capability at UB
processor," says Skolnick.
these days, the word that often comes to mind is "staggering."
"So if you don't have on the order of several thousand proThat's because in September 2002 a new Dell supercomputer cessors, you just can't reasonably do it. But if you have 4,000
cluster was installed in the university's Center for Computational processors, which we do, then, theoretically, it could take only
Research (CCR).
18 days," he predicts.
Weighing more than 80,000 pounds, the cluster has a capacity
And that's only for one genome. Skolnick and his colleagues in
to perform 5.8 trillion operations per second; it contains 4,120 the Department of Structural Biology in the UB School of
Pentium processors, more than 2 trillion bytes of random access Medicine and Biomedical Sciences are studying numerous gememory and 160 terabytes of storage.
nomes, including those of pathogens and organisms such as the
Currently more than 50 scientists at UB are engaged in mouse, the basis for many models of important human diseases.
bioinformatics research in the fields of genomics, proteomics, They also are studying less complex genomes, an understandbiophysics, biology, pharmaceutics, chemistry and computer ing of which will provide the basis for better approaches to the
science. Many, like Skolnick, will use the supercomputers in the human genome.
CCR for their research, which ranges from molecular-structure
After important protein structures are determined-a huge
determination and computational chemistry to materials sci- undertaking in itself that requires collaboration with experi-

�mentalists-comes what Skolnick calls "the hard part," the
analysis of each structure to determine its role in biochemical
function and how it may both influence, and be influenced by,
cellular processes involved in disease.
"Ultimately, what we want to do is to relate genotype (what's
happening genetically) to phenotype (what's happening clinically)," he says. "What we want to find is, What's the physiological
manifestation of this protein structure in this cellular pathway?
"The overall goal is to develop personalized medicine, which is
based on understanding how a drug affects one person versus how
it affects another, " he adds.

the interacting proteins that will help scientists discover their
role in biochemical pathways.
"That's what our method aims to do," he continues. "Using
our supercomputer, we can start to see how the path fits together,
how this enzyme interacts with that small molecule, or functions in a cascade of cellular processes.
"Ultimately, you want to know how the expression of these
particular molecules relates to a particular phenotype; for example, whether a particular set of proteins causes a certain kind
of cancer," he says.

Appetite for Data
Connecting the Dots
kolnick and his team already are making headway in
connecting those dots. In the November 15, 2002 issue
of Proteins, the team published results developed while
Skolnick was at the Danforth Plant Science Center in
St. Louis that provide the first large-scale (genome-based)
ability to predict protein-protein interactions. *
"With that research, we are now moving toward an understanding of how the whole system works-what's known as
systems biology, which is the key revolution in the post-genomic
era," he explains.
According to Skolnick, the Protein Data Bank, the international "public library" of solved protein structures from which
scientists draw data, contains not just isolated molecules but in
many instances solved compounds of two or more proteins
interacting with each other.
"Lots of cellular signals are mediated by these protein-protein
interactions," he explains, "but it's a very crowded party, and we
want to know exactly who's interacting with whom. Often, the
function of one protein can be deduced by studying the proteins
with which it interacts."
Skolnick conjectures that perhaps there are hundreds of millions of these interactions, a seemingly intractable problem.
However, he adds that the process is greatly accelerated if you
have a computational method that helps pinpoint the sites on

For bioinformaticians like Skolnick, these unprecedented challenges carry with them unprecedented opportunity, for these
scientists are getting a first glimpse of the dazzling array of
complex cascades of the biochemical activities that make up
human life.
"Right now, there are only about 500 proteins that are targets
of existing drugs, and there are 35,000 genes," explains Skolnick.
"The questions we are going to attempt to answer include exploring what makes a drug target a drug target? Can we predict
interesting drug targets? Can we suggest cocktails of drug leads?
"There is an immense and voracious appetite out there for
the kind of data we are generating. "
If the post-genomic era lives up to its promise, then experimentalists working in laboratories around the world will eagerly
devour these fresh computational results and in the years ahead
will translate them into findings that, step by step, will guide the
development of medications whose power and precision can
today only be imagined.
4D
•For a detailed description of the article published in the November 15, 2002. issue of
froteins by Skolnick and his team in which they describe a promising new algorithm
they have developed that can predict interactions between proteins whose struc·
tures are unsolved, visit the University at Buffalo's New Services Web site at http://
www.buffalo.edu/news and enter the keyword "Skolnick" in the search engine.

�RESEARCH

E

W

S

Virtual Surgery, Virtual Organs
Living Anatomy Program takes on a life of its own
esearchers at the Uni- if I could learn how to do an
versity at Buffalo are operation that poses a high
combining 21st-century mortality risk-one I may
materials and comput- never see until I'm called to
erized sensors to create do it at 3 p.m. on a Tuesdaya simulator for surgical if I can find a way to allow
training with "organs" that people to learn surgery techfeel, smell and respond like liv- niques quickly and efficiently,
it could save lives."'
ing tissue in the human body.
That was in 1993. Today
The work is being led by
David Fineberg, MD, clinical Fineberg is working with UB
assistant professor of surgery computer scientists, engineers,
and oral and maxillofacial sculptors, materials experts,
in the UB School of Medicine pharmaceutical firms, highand Biomedical Sciences, who school curriculum coordinawants to change the way sur- tors and a veterinary school to
create a surgical version
geons train. In fact, he
of a simulator he has
also wants to change
BY
named "The Living
LOIS
the way content is deBAKER
Anatomy Program."
livered across many
In the process, he has
industries and disciplines, including the teaching come to believe that the technology being developed for a
of mathematics and science.
Fineberg's idea took shape surgical simulator could have
nearly 10 years ago when he applications far beyond that
was a trauma surgery resident original goal.
at Erie County Medical Center.
''I'm interested in creating a
A young woman arrived at profound, in-depth immersion
the hospital with internal in- into content through a technojuries sustained in an automo- logy platform based on interacbile accident the day before tive physical-virtual models,"
she was to be married. The im- says Fineberg. "Users will be
pact had ripped her liver from able to enter, become immersed
its tethering vessels, and her ab- in and manipulate computerdomen was filled with blood. generated content in a very
The trauma team worked for natural way by using their
three hours in a frantic but fu- hands-a development that
tile attempt to save her life.
represents a new step in the
'Til never forget that," says evolution of a human-systems
Fineberg. "It really affected me. approach to interface developI thought, 'If! had had a model ment. This can be accomplishto practice that procedure on, ed with custom-made physical

34

ltffalo Physician

Wi11ter

2003

objects that direct motion of
related virtual models."
In referring to "a humansystems approach," Fineberg
explains that he is collectively
describing a myriad of interrelated components that are customized to represent sensory
systems of the human body in
order to allow, for example, a
surgeon-in-training to communicate more effectively with
an artificially generated environment. In the case of the
Living Anatomy Program, "the
sensation of touch and its
relationship with vision is the
focal point," he explains.
Fineberg sees a variety of
potential applications, from
teaching math and science to
high school students, to using
simulation to train workers to
perform potentially risky tasks,
such as operating industrial

machinery, without actually
putting them in harm's way
while they're learning.'Tm
looking to change the way content is delivered across all industries and disciplines," he says.
The surgical simulator
would showcase the technology's potential and function as a prototype for this
human/virtual reality interface.
Prospective surgeons, like
all medical students, learn about
the body from a cadaver, which
is useful but far from optimal,
says Fineberg. "A cadaver is
cold, hard and preserved. It
bears little resemblance to the
living body.
"With a surgical simulator,
surgeons-in-training could
learn, for example, how a ruptured spleen feels or how to
locate a torn blood vessel in a
blood-filled abdomen."

�FINEBERG WILL USE 21ST-CE TURY MATERIALS AND ENDOW THE MODELS
WITH COMPUTERIZED SE SORS TO CREATE PSEUDO-ORGANS THAT WILL FEEL,
SMELL A

D RESPO

D LIKE LIVING TISSUE I

Fineberg and Thenkurussi
Kesavadas, PhD, UB associate
professor of mechanical and
aerospace engineering and director of UB's Virtual Reality
Laboratory, have begun working toward that goal, one organ
at a time, with $100,000 in development funds from the ew
York State Office of Science
Technology and Academic
Research (NYSTAR).
rgan models, per se, are
nothing new, but Fineberg's organs will be unlike anything that exists
currently. He will use 21stcentury materials and endow
the models with computerized sensors to create pseudoorgans that will feel, smell and
respond like living tissue in
the body.
"This has not been done before," says Fineberg. "You have
to have someone who knows
what human organs feel like
committed to the project to
make it work. o one even
comes close to our technology
of combining these organs
with the computer interface."
To date he has made molds
of the liver and spleen using
cadaveric organs as models .
He is now working with Polytek, a materials company, to
find polymers that feel like
living tissue with which to fill
the molds.
The University of Ottawa
Heart Institute's Medical
Device Department has also
offered engineering assistance and mentoring services
on the project.

THE BODY.

Translating the tactile information into electronic data
falls to Kesavadas. He is helping to capture the properties of
human tissue using his virtualreality glove, a device that collects data on what the wearer is
feeling through sensors located in the glove's fingertips.
Kesavadas is creating a database of information that describes the biomechanical
properties of soft tissue under
various conditions.
Just as flight simulation involves more than manipulating instruments on a panel,
surgical simulation, to be
truly representative of reality,
must recreate the sense of
urgency and controlled chaos
of the surgical suite.
"There is a complex atmosphere that exists in a surgical
setting that must be reproduced for a realistic simulation," Fineberg says. "That includes sound, people walking
around, and algorithms of
activities that are occurring. A
computer-generated environmentcan capture much of this."
Before the project can reach
this point, the model organs
likely will have a first life as
individual teaching tools .
Fineberg plans to market them
and the technology platform
for a number of uses to generate funds to finish the surgical
simulator prototype.
A firm in Rochester, ew
York, is interested in marketing a complete set of organs for
teaching biology and anatomy.
Veterinary schools also have

shown interest in models of
dog organs for use in training
veterinary surgeons. (Washington State University's College
of Veterinary Medicine is currently formalizing a relationship with Fineberg to install a
lab to use his models as alternatives to live dogs in the training
of veterinary surgeons.) The
spleen model will be marketed
to physicians who treat bloodrelated diseases. Kesavadas is
working on a virtual-reality
"overlay" of the spleen, which
could make it appear to be injured, inflamed or of a particular age.

Fineberg plans next to produce a "liver trainer," for use by
anyone who needs to learn the
liver's physiology; a pancreas
model will follow.
"What we are working
toward doing is linking spatial
position and motion of physical objects with related images
in a computer-generated visual
scene, so that we can selectively
control objects in a virtual
world," Fineberg says. "This will
allow us to merge the physical
with the virtual. We cannot do
this without quite a bit of
front-end development in both
the physical and the virtual
area, and that is what we are
doing now."
&lt;P

for every ring purchased a $10 donation will be
made to the University at Buffalo alumni fund

/

February 12th·14th , 10am to 4:00pm

place an order call 1.800 .424.1492 or visit www.jostens.com
C 2002 Jostens Inc. Printed in U.S.A. 02·0920

Winter

2003

l11fale Pbysiciae

35

�RESEARCH

E

W

S

Rich Vein of Data

Women's Health Initiative a catalyst for new studies

hen researchers in the
University at Buffalo
School of Medicine
and Biomedical Sciences began recruiting
women to participate
in the three-pronged Women's
Health Initiative (WHI) in 1993,
the relationship of gum disease
to osteoporosis was not one of
the questions they were seeking
to answer.

generation, all of which
The goal ofWHI is to
BY
are direct spin-offs of
gather essential clinical
LOIS
the original initiative.
BAKER
data on the major disToday, a decade after
eases affecting women,
the initiative was launched, hun- using women as subjects. With
dreds of other spin-off projects that mission in mind, researchare under way at the WHI's 40 ers set out to determine, once
clinical sites across the country, and for all, if a woman's risk of
catalyzed in whole or in part by developing coronary heart disthe 12-year, $625 million initia- ease,breastandcoloncancer,and
tive funded by the ational In- osteoporosis could be lowered
stitutes of Health. The WHI is through three interventions:
hormone replacement (estrogen alone or with progesterone);
vitamin D and calcium supplementation; or a low-fat diet.
Meanwhile, myriad ancillary
studies have begun addressing
questions that weren't even being asked in 1993.
"This is one of the legacies of
WHI," says Jean WactawskiWende, PhD, co-director with
Maurizio Trevisan, MD, ofUB's
WHI Vanguard Center. "With
comprehensive health data on
162,000 women, we have an
invaluable mine of information
to use to advance public health.
I
think we'll be learning from it
Jean Wactawski·Wende, PhD, co-director with Maurizio Trevisan, MD, of University
for 50 years."
at Buffalo's Women's Health Initiative Clinical Vanguard Center
UB's interest in the link beIn the "one-thing-leads-to- the largest clinical trial ever un- tween oral health and osteoanother" nature of scientific dertaken in the U.S.; currently, porosis dates to the early 1990s.
research, however, investiga- some 162,000 women are en- Researchers in the Department
tors in UB's WHI Clinical rolled in it nationwide, includ- of Oral Biology in the School of
Vanguard Center have sincere- ing 4,000 in Buffalo.
Dental Medicine in 1995 received $3 million in funding to
Historically, clinical trials ported results of a pilot study
conduct a series of studies on have been conducted only on demonstrating that women with
the link between the two condi- men. As a result, treatments increasing levels of periodontal
tions. UB also is taking part in tested exclusively on men were disease showed corresponding
trials examining the effect of prescribed for women without losses of bone mineral density.
estrogen on memory, Alzhei- evidence that they would receive That study, supported in part by
mer's disease and macular de- the same benefit.
the U.S. Public Health Service,

36

l ulfalo HysicilD

Wi11ter

2003

led to a $750,000 grant from the
U.S. Army to investigate this link
in UB participants enrolled in
one arm of the WHI study.
Based on those findings,
which duplicated the pilot
study results, UB received
$2 million in the summer of
2001 from the ational Institute of Dental Research to
follow the women for four
more years and document any
gum disease-osteoporosis link.
Having a periodontal-disease
clinic in place for this WHI spinoff study provided the opportunity for UB researchers to move
forward quickly on another
major investigation: the link
between periodontal disease
and heart disease.
Trevisan and co-principal
investigator Robert J. Genco,
DDS, PhD, vice provost and
SUNY Distinguished Professor
in the Department of Oral Biology, received $7 million from
the a tiona! Institute of Dental
and Craniofacial Research in
October 2001 to plan and conduct a pilot study to determine
if treating periodontal disease in
patients who have had one heart
attack will prevent a second.
Genco was one of the first
scientists to show a connection
between inflammation from
periodontal disease and heart
disease. He has been working
for several years to further
elucidate this connection and
identify the particular oral
pathogens involved in inflammation in the blood vessels.

�Inflammation now is considered an important cause of heart
disease, and research is progressing in this area on several fronts.
Perhaps the richest WHI vein
available to be mined is the data
bank of blood samples taken
from alll62,000 participants at
the start ofthe initiative. As various conditions and diseases develop in participants, these blood
samples can be scanned for disease "markers," that could form
the basis for future screening
tests designed to catch diseases
in the very early stages.
none study, Trevisan and another group of WHI investigators led by Paul Ridker of
Harvard University Medical
School are analyzing the sam-

pies of WHI participants who
develop cardiovascular disease,
looking for such clues. This research will help detect blood
markers that can be used to
identify people who are at risk
of having a heart attack before
any symptoms develop.
UB researchers and scientists at additional WHI clinical
sites also are studying CA 125, a
blood marker for ovarian cancer, using this large database.
The collection of blood
samples could lead to the discovery of currently unknown disease markers and new methods
of early identification for a wide
variety of conditions, according
to Trevisan. "The fact that we
can wait for a disease to show up

and then look for clues in the
specimens already collected and
stored in the WHI blood sample
bank will give us better and
quicker ways to identify disease
markers," he explains.
The studies of estrogen replacement and its relationship
to Alzheimer's disease and
macular degeneration are being carried out at UB and several other WHI clinical centers
in participants over the age of
65. Even though the estrogen/
progesterone arm of the trial
has been halted, these women
will continue to be followed to
determine if hormone replacement was beneficial in preventing dementia or vision loss.
Women in the estrogen-

alone arm of that trial, which
was not halted, will continue
their participation as scheduled. Results of those trials will
begin to be released when the
WHI ends in 2005.
As the end of the initial
WHI trial approaches, UB and
other WHI clinical centers will
be applying for additional
grants to follow participants
into the future.
"The idea is to keep a
data stream going," notes
Wactawski-Wende. "The intention is to keep the cohort
together. I look at this as a lifespan study.
"There'ssomuchdata,people
will be analyzing it and learning
from it for years."
4D

Phillips, Lytle understands that health care providers face unique legal challenges. HIPAA, STARK,
compliance issues, DOH regulations, reimbursement, the OPMC, and let's not forget about MFCU
audits. These are all hot topics that we are prepared to help you with .
Experience

•

•

Breadth

Depth

Have questions or concerns? Call or e-mail Lisa McDougall, Esq., the health care practice group
coordinator, at (716) 847-5478 or lmcdougall@phillipslytle.com.
PHILLIPS.

LYTLE.

HITCHCOCK.

A T T 0

BLAINE

8

HUBER

LLP

R N E Y S

est.1834
3400 HSBC Center, Buffalo, NY 14203
(716) 847-8400 website: www.phillipslytle.com
BUFFALO

•

FREDONIA

•

jAMESTOWN

•

NEW YORK

•

ROCHESTER

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CUlture

ditor's Note: Last summer, Stephen Wear, PhD, associate professor in the Department
of Medicine at the University at Buffalo School of Medicine and Biomedical Sciences,
and co-director of the UB Center for Clinical Ethics, was invited to be a visiting
professor at the Graduate Institute of Philosophy, National Central University, in
Chung Li, Republic of China (Taiwan). Wear, who holds adjunct appointments in
the gynecology/obstetrics and philosophy departments at UB, sits on various ethics
committees in Buffalo, including those at the Veterans Affairs medical center (where
the UB Center for Clinical Ethics is located), South Buffalo Mercy Hospital, Erie County Medical Center,
Kaleida Health System and Millard Fillmore Hospital. He has published some 40 articles on a wide range of
bioethics' topics and has authored a book titled Informed Consent: Patient Autonomy and Clinician Benef'icence within Health Care, which is now in its second edition and has been translated into Italian.
At the invitation of Buffalo Physician, Wear has written the following article that encapsulates observations
he made during his stay in Taiwan regarding that country's efforts to establish ethical guidelines for health care
that incorporate both traditional and modem approaches to treatment.

-5. A . Unger

f

rom July 3 to August 4, 2002, I had the privilege of
being a visiting professor at the Graduate Institute
of Philosophy at the ational Central University
in Chung Li, in the Republic of China (Taiwan). During my month-long stay, I delivered a series oflectures
and grand round presentations and participated in a
number of case conferences at health-care facilities in
the Chung Li and Taipei area. In addition, I collaborated on various research projects that focused on
ethics committees and bedside ethics consultation,
and consulted with staff at the institute, as well as with
physician and nursing faculty at the Yang Ming School
of Medicine in Taipei.
Technologically, the Taiwanese seem to be about
on par with the United States. For example, I was
shown medical facilities that boast enormous 200-bed
intensive care units, was briefed on very active research
efforts in the teaching hospitals, and observed medical
student/resident education models that are fairly similar to our own. One notable difference in the educational system, however, is that students begin medical

38

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school right out of high school and earn their medical
degree after a seven-year course of study.
As I met and became acquainted with faculty and
attendings at various hospitals, I was surprised to
discover that a large percentage had been trained in
the West, particularly in the United States.
Taiwan has what is probably the last large, concentrated population in which traditional Chinese
culture abounds, as the communists have done everything they can to eradicate it on the mainland since
they took over in 1949 (e.g., the Great Leap Forward,
the Cultural Revolution, and the Red Guards).
Given that the focus of this ancient tradition is on
the family as the basic social unit-not on the individual, as in the West-this produces very different
clinical approaches to patient care than what we have
become accustomed to in our culture. For example,
even when the patient is competent, families are the
first to be approached with diagnoses and treatment
recommendations by staff. Respect for patient confidentiality is thus not a major ethical principle in

�Taiwan, and a family's demand that a patient not be
told bad news is usually honored.
It was also interesting for me to learn that informed
consent for procedures may be obtained by law from
either the patient or the family.
While the technological level of health care in Taiwan seems in many ways to be as high as ours, the
country is about 15 years behind the West in grappling with the issues of medical ethics that inevitably
accompany such technology. They are just now beginning to deal with such issues as do-not-resuscitate
orders, they have not yet made provision for advanced directives and withdrawal of life support rarely
occurs. In this sense, they are behind us; however,
their much higher respect for families as surrogates
has allowed them to deal with many death and dying
issues more comfortably than we have in the West.

B

efore I left for my visit, I was warned that, in general, Taiwanese health-care professionals are not
interested in a rendition of Western individualistic, patient-centered medical ethics. The reason for
this sensitivity, I was told, is that this approach would
be perceived as just another form of Western imperialism, something the Chinese have certainly had quite
enough of over the course of the past two centuries.
Given the emphasis on diversity in our own
culture, and out of respect for my host country's
mores, I was of course prepared to avoid any affront
in this regard.
Interestingly, however, throughout my visit, my
Chinese colleagues consistently wanted to know how
a given issue or case would be dealt with in the West.
On closer examination, it soon became apparent to me
that they were in many ways wrestling with the same
sorts of concerns we had wrestled with 25 years ago,
when bioethics arose in reaction to the Western
tradition of physician paternalism. In particular, they
expressed concern that the well-known lack of confidentiality in their medical culture has resulted in a
tendency for patients not to be candid when interviewed by physicians. They also report that, for the
same reason, people with AIDS come in for treatment
much too late.
As to truth-telling and patient autonomy, anumber of the cases I was presented with involved patients with treatable malignancies whose families
had forbidden the doctors to tell them their diagnosis and took them home for traditional Chinese
medical therapy, only to have the patient return a few

months later when their disease had metastasized
and was untreatable.
In response, I found myself wondering if we in
the West are being too humble about our progress in
medical ethics or too accepting of cultural diversity.
In effect, I felt that my hosts were most concerned
about the negative, harmful effects of a paternalistic
medical ethic, just as we had been a few decades
ago. This concern was demonstrated not just in their
more general discussions, but over and over again in
the cases they chose to present to me in their healthcare institutions.
It's not that I feel that the Western individualistic
approach to bioethics has the full answer for the
Chinese, any more than it does for Western cultures.
Often in the
West our approach to patients commits
the opposite evil
of not involving
their loved ones
at all, an approach that the
traditional Chinese practitioner
would not allow.
As my visit
drew to a close,
however, it became increasingly apparent
to me that cultural diversity
only goes so far,
and that there
may well be a
bedrock of desires, expectations and needs
common to all patients that any culture and medical
establishment must somehow accommodate in
order to be successful. Many clinicians in Taiwan are
seeing traditional Chinese culture, on its own terms,
as challenged by the new technologies and therapies
of 21st-century medicine. As a result, I came to
understand that they are curious not so much about
how we in the West deal with such issues, as about
how their own tradition can deal with them as they
move forward. 4D

Winter

2003

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�DEVELOPMENT

E

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The Road Best Traveled
By Linda J. Corder, PhD, CFRE

UR STUDE TS TRAVEL many paths to reach
medical school. One of the most interesting journeys is
that of Kim Griswold, MD '94, MPH, whose work with
refugees is highlighted in this issue.
Kim grew up in San Antonio but moved East to attend
Bard College, where she majored in acting. She then took
a job in summer stock in Virginia, later moving to Boston
to work for the Boston Repertory Company and to be
near her parents, who had relocated to Massachusetts.
When her mother became ill with breast cancer, Kim
moved home to help. Shortly after her mother's death,
she spent several weeks in the hospital herself, recovering
from injuries sustained in a horseback
riding accident.
With her acting career on indefinite
I
I
hold, Kim spent many long hours in the
hospital bed thinking about what she
would like to do with her life. Her primary doctor provided a possible answer:
"nursing." She enrolled in a two-year program at Syracuse University and after
graduation went to work at Massachusetts General Hospital in neurology. After five years, a neurologist-mentor asked
ifshe had ever considered medical school.
She said she hadn't because she was sure
she "couldn't do it"; but the question led
Kim to realize she needed a new challenge. Eventually
this same mentor suggested public health, and Kim
entered the MPH program at Yale University.
Her work at Yale brought to the fore an interest in
displaced populations, and a fellowship resulted in her
spending ten months at Oxford University, where she
studied the delivery of health-care services.
After she completed her MPH degree, Kim's father,
who had remarried and moved to Buffalo, suggested that
Kim consider moving to Buffalo, as well. She did, and
took a job writing grant proposals for UB's School of
Health Related Professions. Later she worked with the
Department of Pediatrics, helping to obtain a grant to
study developmental problems of children with severe
disabilities. She then began to teach research methods in
the Family Medicine Department and approached a

40

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mentor-supervisor with a request for
flexibility so she could pursue a PhD.
He said no, but added that he would
support her studies if instead she pursued a medical degree.
This time she took the suggestion
seriously and went back to school to complete prerequisite science courses. As the application deadline approached, her mentors wrote letters acknowledging her
nontraditional path, but whole-heartedly endorsing
her admission.
Once admitted, it wasn't easy. The socialization process was " overwhelming," says Kim, who
turned 39 the day of her first anatomy
exam,
which she failed. But she worked,
I
I
she studied, she cried, and by the end of
I
her first semester, she had passed everyI
thing. It was the turning point Kim
needed, and from then on, she knew
she would succeed.
In deciding on an area of practice,
Kim was conflicted until one day she
finally "just knew family medicine was
it." The field allows her to combine all
the elements she encountered on her
road to medical school, including public
health and research. And, along the way,
Buffalo had become home: Her family and friends are
here, and she feels she is in her element in the city,
whether it be practicing on the west side, teaching
medical students or conducting research in the Family
Medicine Research Institute.
In addition to other ways that Kim gives back, she has
initiated two endowments: a scholarship fund to honor
Adelaide and Brendan Griswold, who encouraged her to
"consider Buffalo"; and the Family Medicine Research
Fund, which will eventually underwrite research combining many of the areas of interest reflected in Kim's
circuitous journey to medical school. 4D
Linda (Ly n) /. Corder is associate dean for alumni affairs
and development. She can be contacted via e-mail at
ljcorder@buffalo.edu; or by phone at 1-877-826-3246.

�Spring Clinical Day
and Reunion Weekend
Class of' 58 /
Mike Genco, MD, '58 and
Mickey Stein, MD, '58

Mark your calendars
It's not too early to plan for the 2003 Spring Clinical Day and
Reunion Weekend.
A cocktail reception will be held Friday, April 25, 2003.
The 66th Spring Clinical Day and Reunion Dinners will
be on Saturday, April 26. For more information, turn to
Patty Duffner's message on page 43, or call the Medical
Alumni Association office at (716) 829-2778.

Our 45th reunion . • • Can you believe
it? We have much to be thankful for
much to look forward to. We'll see you in April!

\Class of '63
Charlie Tyrone, MD, '63
The face of medicine has changed drastically since 1963.
Has yours? Make plans now to attend our 40th reunion in
Buffalo. Let's get reacquainted and reminisce about the

Class of' 43 /

good old days.

Ralph Behling, MD, '43
Plans are still evolving! There are 37 "old timers" who are contemplating
our 60th! I hope to be there and hope you will be there too.

Class of' 68 /
Tom Cumbo, MD, '68 and
Bob Milch, MD, '68

Class of '48 /
Dan Fahey, MD, '48

We are putting together a 35th
reunion weekend that should prove
enjoyable, and we sincerely hope you will make every effort to attend.

Plans are well underway to celebrate the 55th anniversary of our graduation from med school. Wouldn't it be
great if all 41 surviving alumni of our class could attend?

/ Class of '73
Arthur Mruczek Sr, MD, '73 and Michael A.
Sansone, MD, '73
We have accomplished great things with our degree from
'73! Our 30th reunion success depends on your participation ••. Come and share your triumphs with us and see how UB has changed!

Class of'53
Bert Portin, MD '53
"Hey everyone, great 50th party planned. Look forward
to seeing you!"

Class of '78 /
David Marchetti, MD, '78
Don't miss a chance to see old friends and get
caught up on what they're up to after 25 years.

W in ter

2003

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Class of '83 /
Ken Zimmerman, MD '83
1983 ••• 2003 -The more things
change the more they stay the same.
Come see for yourself.

Which can
you afford
to waste?

/Class of '88
Helen Cappuchino, MD, '88
and Andy Cappuchino, MD, '88
1988--We were listening to
Michael Jackson sing "The Way
You Make Me Feel" and Bobby
McFerrin sing "Don't Worry Be Happy." Gorbachev
withdrew troops from Afghanistan and the U.S. PeachKeeping Force won the Nobel Peach Prize. The World
Series was between two teams from California. Andy still
had hair and we had only one child! AND, we all graduated

FEATURES

BENEFITS

• Electronic submission of all
major insurance claims

• Increase your accounts
receivable turnover

• Follow-up of all unpaid claims
and open patient accounts

• Improve collection ratio and
reduce bad debts

• Advisement on and assistance
with insurance carriers and
government regulations

• Optimize revenue through
proper monitoring of charge
master

• Choice of processing
options including on-line
or full-service

• Eliminate costs associated
with computer software and
maintenance

• Easy start-up or conversion
from present billing system

• Transition smoothly and quickly
while maintaining cash flow

• Appointment scheduling
software available on request

• Improve office efficiency and
patient satisfaction

from UB med school! Join our classmates on April 26 to
reminisce and have fun. We really hope to see you for this
great weekend!

Class of '93 /
Ray Ogra, MD, '93
"Can you believe it's been over 10
years since Renier had his accident
with bleach and transformed himself
into "Carrot-Top" ? Or since yours
truly asked the stupidest question ever (hint: cadaver
and wax·injected vessels)? Do you remember the Follies?
The H.O.P.E. clinic? The Dive of the Week? The Talent
Show? We've all come so far and have so many great
memories to share, so come join us this April for our
loth year class reunion!

• Expertise on existing and new • Assure your patients' rights are
corporate compliance guidelines protected
• Practice management with
• Gain peace of mind from
professionally trained staff and
knowing that your finances are
experienced C.P.A.'s
being managed optimally

/Class of'98

Thomas A. Maher, C.P.A.
President

Michael Zionts, MD, '98
Can you believe it's already been five
years? Come back and see who is doing

MEDICAL BILLING
SPECIALISTS

what, and where!

42

1111111 Pbysitill

Wint e r

2 00 3

50 Alcona Avenue
Amherst, NY 14226
Tel: (716) 834-1191
Fax: (716) 834-1382
e-mail: pbs50@aol.com

�Dear Fellow Alumni,
he highlight of the year thus far for the Medical Alumni Association (MAA ) was the Past President's
Dinner, in which we honored our Distinguished Alumnus of 2002, Thomas Lawley, MD '72, dean of
the Emory School of Medicine (see article on page 23 ). University at Buffalo has had many alumni who
have made significant contributions to the field of medicine, but Tom is really special, and I
was honored to be able to present him with this award!
As I mentioned in my last message, Spring Clinical Days will be held April25-26, 2003.
This year Marty Brecher, program chair, and I would like to highlight the UB Center of
Excellence of Bioinformatics and the Buffalo/Niagara Medical Campus (see article on
page 32 ). The welcome cocktail party will be held on April 25 (Friday night) at the Jacobs
Executive Mansion (the old Butler Mansion ) on Delaware Avenue. The formal program
on bioinformatics will be held Saturday morning, April 26, in Hillboe Auditorium at
Roswell Park Cancer Institute, and the speakers will include Dr. Jeffrey Skolnick, who will
deliver the Stockton Kimball Lecture, Dr. Bruce Holm, Dr. Robert Genco, and Dr. Rob
Bakshi. An overview of present and future plans for the Buffalo/ Niagara Medical Campus will also
be provided. Following the lectures, a luncheon will be held at the Buffalo Club. This should be an
exciting conference, which I know both out-of-town and local alumni will enjoy.
In another development regarding one of the MAA's most successful programs-the PhysicianStudent Mentoring Program-! would like to announce that Debra Stamm, assistant dean for student
services in the Office of Medical Education (OME), has graciously agreed to assume administrative
responsibility for the program, with support from our MAA Governing Board member Marty
Mahoney. The program had previously been administered through the Office of Development and
Alumni Affairs, which recently underwent staffing changes that limited its ability to continue
management of the program. The staff in OME maintain close contacts with the medical students,
and we feel they will do an excellent job of matching students with the appropriate mentor.
Another important change in the MAA relates to our finances, including dues and expenses, which
up until now had been managed by our administrative secretary, who retired last year. After much
thought, the Governing Board has decided to enlist the services of the University at Buffalo Foundation (UBF) to collect dues and manage our accounts. UBF has experienced accountants with auditing oversight, and I personally believe these professionals will offer an increased level of financial
security for our organization.
Finally, the Medical Alumni Scholarship Endowment has grown significantly following a very
generous gift from AI Dobrak, MD '39. Our goal is to raise the endowment to 1 million so that we can
increase the number of scholarships we give each year (see page 22 for this year's recipients of the
scholarship). Please donate generously to your class gift for the scholarship endowment!
And please remember to put Spring Clinical Days on your calendar. We're very excited about the
program, and know you will enjoy seeing the new campus and hearing about plans for its future.

J,b~,:?.~

President, Medical Alumni Association

Win t er 2003

llfllll Pbysician

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Cedric M. Smith, MD '52
(started with the
Class of '52; graduated
with the Class
of '53, with an MD/MS
degree.) Currently,
Smith is a professor
emeritus in the Department of Pharma·
co logy and Toxicology at the University at
Buffalo School of Medicine and Biomedical
Sciences, and associate research scientist in
UB's Research Institute on Addictions. He also
teaches pharmacokinetics and sources of
quality drug information to residents in
psychiatry. He spends the majority of his time
following up on publications he has authored.
(Over the past ten years, he has authored 22
scientific/medical articles and edited two
pharmacology textbooks and 25 abstracts
and book reviews.)

1950s
Phoebe Sat uren, MD '52,

physical medicine and
rehabilitation, lives in
Nyack, Y. She writes:
"The May 2002 50-year
reunion of the Class of
1952 was spectacular, as
was our class party and
the clinical day. I spoke
to the residents in rehab
about the growth of pediatric rehabilitation over
the years. Dr. Thomas
Polisoto hopes to invite
more alumni physiatrists
to lecture. I also attended
a Sunday brunch with
some of the students who
wanted to meet with
alumni. I think this event
should continue."
E-mail address is:
saturendoc@aol.com.

He writes: win addition, I have some pet
projects such as renewing antique family

Ben Celniker, MD '57, ob-

photographs, cultivating numerous medicinal

stetrics-gynecology, lives
in Phoenix, AZ, where he
works in a group practice
and is on staff at the
Maryvale Hospital Medical Center. Favorite
medical school memory:
"Putting sugar in Harris
Kanel's urine in biochemistry class."

plants, and studying the yellow bird of the
tropics-the Bananaquit and its appetite for
sugar and alcoholic beverages.
wl am also involved in an active medical/
legal consulting practice specializing in
describing the time course of alcohol effects
and blood levels and adverse reactions to
psychoactive drugs.
" My wife, Katerina Kobakof, and I are
blessed with five children and nine interesting
and active grandchildren. We are challenged
to keep up with gardening around our house
that over looks the Niagara River. During at
least part of the winter you can find us
walking/biking the beach of Jekyll Island, GA.
Although we are beginners at golf, we fre·
quently conclude, along with many others,
that golf 'is a good walk ruined. '" E·mail
address is: cms23@buffalo.edu.

....

la f f al1

Hysici11

Winter

2003

1960s
Richard H.
Daffner, MD
'67, is a di-

agnostic radiologist
affiliated with Allegheny
General Hospital in Pittsburgh, PA. He and his
wife, Alva, have two

children: Marc, 33, and
Scott, 29. Favorite medical school memory:
"Summer radiology
preceptorship with Dr.
George Alker in 1966,
which convinced me to
become a radiologist."
E-mail address is:
rhda ffner@netsca pe. net.

David Silverstein, MD '72,

ophthalmology, lives and
works in Saratoga, CA.
Favorite medical school
memory: "Saturday
morning anatomy
with 0. P. jones."
E-mail address is:
dsseyedoc@aol.com.
Mark Zlotlow, MD '72,

1970s
Sanford J. Holland, MD '72,

anesthesiology, lives in
Scranton, PA, and is on
staff at Moses Taylor
HospitaL Favorite medical school memories:
"The 'Kent State' year
(1970): Erie County K-9
cops on campus; tear gas
in Norton Union; no
sophomore final exams
in pharacology, pathology or microbiology."
E-mail address is:
sanfordh@mth.org.
Joanne Levitan, MD '72, is a
diplomate of the American Board of Surgery,
and the American Board
of Plastic
Surgery,
with added
qualifications in
surgery of the hand. She
lives and practices in St.
Clair Shores, MI. She is
in group practice and is
affiliated with the Harper
Hospital in Detroit and
the Cottage Hospital and
Bon Secours Hospital in
Grosse Pointe.

pediatrics, lives in Sacramento, CA, and is on
staff at the Kaiser Foundation Hospital in
Sacramento and
Roseville. His favorite
medical school memory:
"Buffalo General HospitaL" E-mail address is:
mark.zlotlow@kp.org.
l ewis R. Groden, MD '77,

ophthalmology, lives in
Tampa, FL. He is director
of the Ophthalmology
Residency Program and
director of the Cornea
Service at the University
of South Florida. He is
also medical director of
Lasikplus Vision Centers
in Tampa. E-mail address
is: doccornea@aolcom.

1980s
Jill Brody, MD '82, internal

medicine, lives in Providence, RI, with her husband, R. Nicholas Camp,
and their two children,
Michael, 16, and Sabrina,
14. Favorite medical
school memories: "Biochemistry with Alexander
Brownie; neuroanatomy
with Harold Brody;
medical sub-internship at
ECMC; getting done with

�Timothy P. Bukowski, MD

Paul B. Karas, MD '87, lives

'87, FlAP, FACS, has opened

in Cheektowaga, NY,
with his wife, Donna, and

a new office (Pediatric
Urology of North Carolina) in Raleigh, NC. Following graduation from
UB, Bukowski completed
his surgical/urology residency at Wayne State
University. After a pediatric urology research fellowship at Cincinnati
Children's Medical
Center, he returned to
Children's Hospital of
Michigan to complete his
accredited pediatric urology fellowship. From
1995-2001, Bukowski was
director of pediatric urol-

anatomy." E-mail
address is: ralph.camp
@verizon. net.
Manuel Leonardo Saint
Martin, MD '82, lives in

Los Angeles, CA, where
he has a solo practice in
forensic psychiatry.
Favorite medical school
memory: "All of it.
Working with Roberta
Pentney, PhD." E-mail
address is: cerberus 1113
@hotmail.com.
Jessica Rockwell, MD '82,

endocrinology, lives in
Cooperstown, Y, with
her husband, Peter
Jederlinic, and their three
children: Nicole, 17,

their three children: Paul
B. (Ben), Jr, 10, Andrew
Jay (AJ), 8, and Catherine,
5. He is in a group practice and on staff at Sisters
Hospital in Buffalo.
Favorite medical school
memory: "Getting accepted to the school as
a transfer student."
E-mail address is:
bandofive @aol.com.

Adam Ashton, MD '87, psy-

chiatry, lives in East
Amherst, NY. He and his
wife, Cindy, have three
children: Evan, 10, Leah,
8, and Alexis, 6. Favorite
medical school memory:
"Playing drums in the
Follies Talent Show
bands." E-mail address
is: aashton@buffalo
medicalgroup.com.

ogy at the University of
orth Carolina at Chapel
Hill, where he received
several teaching awards;
and from 2001-2002, he
was chief of pediatric
urology at Children's
Hospital of Michigan
in Detroit.
Bukowski is a Fellow
of the American College
of Surgeons, F;:i!cw of the
Society of Pediatric Urology, and Fellow of the
American Academy of
Pediatrics, Section on
Urology. He has an active
interest in laparoscopy
and fetal urologic intervention. He and his wife
have four children.

Sheri Baczkowski, MD '92,

is an obstetrician/gynecologist and lives in
Williamsville, NY. She

Bonnie Orzech, MD '87, is a
pediatrician and lives in
Finksburg, MD. She and
her husband, Bert Nixon,

assnotes

Alex, 15, and Eric, II.
She is board certified in
internal medicine and
endocrinology and is on
staff at Bassett Healthcare.
Favorite medical school
memory: "Biochemistry
classes with Alexander
Brownie."

and their one-year old
daugher Emma. She
completed residency
training in neurology at
the Mayo Clinic in 1996
and is currently on staff
at Fairview Southdale.
E-mail address is: jald@
dnamail.com.

have three children:
Bryan, 7, Beth, 4, and
Brooke, 2. Favorite medi-

and her husband, Jerry
Wild, have two-year-old
twins, Jenna and Mia.
Favorite medical school
memories: "Dive of the
week, studying in the
Study Room, the holiday
part and the formal."
E-mail address is:
wildplace@aol.com.
Judine Davis, MD '92,

cal school memories:
"Friends, parties,
snowdrifter!" E-mail address is: bfnbon@aol.com

1990s
Janiece Aldinger, MO '92,

lives in Edina, MN, with
her husband, Tim Clavin,

Winter

2003

obstetrics/gynecology,
lives in Hamburg, Y,
with her husband,
Jeffery, and their twoyear-old son Liam
Jeffrey Davis. She works
in a group practice and
is on staff at Sisters
Hospital and Kaleida.
Favorite medical school
memory: "Transition
from second to third
year, after exams and
boards-a really great
celebration!"

l uff a l• Pb ysiciaa

45

�CLASS

Mark Ippolito, MD '92, lives

in Davidson, NC, and is
on staff at the Northeast
Medical Center in Concord. He and his wife,
Donna, have two chi!dren: Arielle and Ethan.
He completed residency
training in neurology at
the ational Naval Medical Center in Bethesda,
MD, in 1996 and a neurophysiology fellowship
at Walter Reed Army
Medical Center in Washington, DC, in 1999.
He is board certified in
neurology, clinical neurophysiology and electro-

NOTES

diagnostic medicine.
E-mail address is:
ippolitofour@yahoo.com.
lldiko Mikos (Gyimesi), MD
'92, plastic surgery, lives in

Louisville, KY, with her
husband, George, and
their two children, Christopher, 4, and Anthony, 3.
She completed residency
training at UT Southwestern in Dallas, TX, in 1997,
and a fellowship in breast
reconstruction in Atlanta,
GA, in 1997. She is on staff
at the Baptist Hospital
East. E-mail address is:
lldikom@aol.com.

Alphonse Daniel Osinski,
MD '92, psychiatry, lives in

Mount Kisco, Y. Residency training was split
between Sheppard Pratt
Hospital in Baltimore,
MD, and Cornell Medical
Center in New York City;
completed a fellowship in
child psychiatry at the
Sheppard Pratt/University of Maryland )oint
Program in 1998. "I am
on the faculty of Mount
Sinai School of Medicine
and work at a satellite
program at the Elmhurst
Hospital of Queens, as a
unit chief on an inpatient

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46

laff al• Hysiciaa

Wi11ter

2003

adolescent psychiatric
unit. (And I love it!)."
Favorite medical school
memory: "In some ways I
took it all far too seriously, although I remember, with thanks, support
I received in various
study groups-and some
fun, too. Sorry I couldn't
make it [to the reunion]

E-ma

this time guys, but I'll
come to one in the future. My best wishes to
everyone for success in
all aspects of your lives."
E-mail address is:
alosinski@aol.com.
Donna (Sinensky) Ferrero,
MD '94, recently moved

from Boston, MA, to

•

•

Classnotes can also be submitted by
e-mail to: bp-notes@buffalo.edu

"Hi, I'm Susan Hunt. I invite
you to come to see my Mom's
new home ... the Amberleigh
Retirement Community.

You 'll smile too!"

.AB~~nf~~nity
2330 Maple Road, Williamsville

For a free brochure or personal tour, call

689-4555

�- ==-----------

Rochester, Y, with her
husband, Vincent, and
their IS-month-old
daughter, icole. She
works as a physiatrist at
Strong Memorial Hospital and is assistant professor in the Department
of Orthopedics at the
University of Rochester.
E-mail address is:
vferrero 17@aol.com.
Jeffrey W. Kanski, MD '94,

has joined the Radiation
Oncology Department
of the Massachusetts
General Hospital and the
faculty of the Harvard
Medical School.

Thomas Burnett, MD '94,
and Carol Ann Killian, MD
'94, are pleased to an-

nounce the birth of their
son,
Matthew
Killian
Burnett.
He was
born
March
14, 2002, and weighed 8
pounds, 2.5 ounces and
was 21 inches long. Big
sisters, Kristen (4 112)
and Lauren (3), love their
little brother and are enjoying preschool. Tom

continues to practice internal medicine in a large
multi-specialty group,
and Carol Ann practices
emergency medicine per
diem at two local emergency departments."
E-mail address is: tburn
@cloud9.net.

got married (September 28, 2002) to
Todd Wilkerson, who
works as a project manager for UPS corporate
headquarters. E-mail
address is: lesleywilke
@aol.com.

Lesley (Orman) Wilkerson,

completed her residency
in internal medicine at
the University of Maryland in June 2001. She
and her husband, Rajat
Bannerji, PhD, MD, subsequently moved to the
Seattle area, where she is
in her second year of an

Rachna Gupta, MD '98, MPH,
MD '97, completed her

residency in pediatrics at
the Childrens' Hospital
of the King's Daughters
in Norfolk, VA, in 2000,
and currently works for
Children's Healthcare of
Atlanta, GA. She recently

infectious disease
fellowship at the
University of Washington. Her husband
is a hematologist/
oncologist at Madigan
Army Medical Center.
They are also excited
to announce the arrival
of their daughter,
Aradhana Bannerji,
born June 16, 2002
(Father's Day). Rachna
welcomes e-mails
from friends from the
classes of 1997 and
1998. E-mail address is:
rachnag@u.washington.edu.

«D

SAVE TIME . ••
Order your medical books online at efollett.com
Mention this ad and get
5°/o off your next in-store
purchase!

T..:J...

University at Buffalo

~ The State University ofNew 1Vrk

UNIVERSITY BOOKSTORE

Main Street • Phone:(716)833-7131

www.buffalo-medical.bkstr.com

Winter

200 3

I u I I I I D Physic i I

D

47

�In Memoriam
Orvan Hess, MD '31

when he administered the

Health for the State of

Orvan Hess,

antibiotic to a 33-year old

Vermont. During his tenure,

MD, '31, died

mother who suffered from

leopold developed one of

on September

scarlet fever and a blood

the nation's first statewide

6, 2002,

infection following a miscar-

system of community-based

after a brief

riage. Her fever broke the

mental health services. After

illness. He

next day and she lived to be

a brief stint as an associate

was 96.
Hess, an obstetrician/

90 years old.
Hess also pioneered the

gynecologist by training, was

study of healing wounds fol-

a medical pioneer who devel-

lowing Cesarean sections.

oped the first fetal heart

"He was a leader in the

professor at The Johns
Health and Hygiene, he
returned to direct patient
care, serving in hospital

medical community," says

settings with the Veterans

physician in the United

Timothy Norbeck, executive

Administration in New York,

States to administer penicil-

director of the Connecticut

Florida and Virginia.

lin to treat a life-threatening

State Medical Society. "He

illness. He spent his 50-year

was also one of the friend-

at Johns Hopkins, he served

career in New Haven, deliver-

liest people on earth-pro-

as a part-time faculty at UB

ing thousands of babies at

fessionally and personally."

emeritus of obstetrics and

.Jonathan Porter A.
Leopold, MD '51

gynecology at the Yale Uni-

Jonathan Porter Aaron

In 1937, while still a
resident, Hess began working on a machine that could
monitor the heartbeats of

In addition to teaching

(1957-1965), the University
of Vermont (1965-19721

Yale-New Haven Hospital and

versity School of Medicine.

leopold, MD '51, died on

and the University of South
Florida at Tampa (19871990). leopold also served
on numerous advisory

grams at the Brookings

huntrealesta te.com

September 22, 2002, at his

boards and participated in

home in Richmond, VA.

leadership development pro-

leopold retired in 1996
after a distinguished career

Institute and the National

of more than 45 years as a

Institutes of Health.

World War II broke out, he

physician, public official and

leopold is survived by

left research to join a U.S.

educator. Following gradu-

his wife of 21 years, Anita,

Army medical team that fol-

ation from UB medical

and his children: Jonathan

lowed General George S.

school in 1951, leopold

P. A. Jr of Burlington, VT;

Patton's Second Armored

completed residency train-

James S., of West Danville,

Division through North Af-

ing in internal medicine at

VT; Christopher B. of

Walter Reed hospital in

Shelburne, VT; and Elizabeth

After the war he resumed

Washington , DC, and

A. leopold of Greensboro,

his research, and in the

served as a captain in the

VT. He is also survived by

mid-1950s he and another

U.S. Army Medical Corps. In

his former wife, Barbara, of

physician developed a ma-

1954, he joined his father,

Shelburne, VT: his brother

chine that could pick up and

Francis, in private practice

David Francis leopold of

of internal medicine. After a

South Burlington, VT: and

record electrical heart signals of a fetus during labor,
launching the field of fetal
cardiology. In the years that
followed , Hess worked to
refine the fetal monitor and
reduce its size.
In 1942, Hess participated in the first clinical
use of penicillin in the world

residency in psychiatry in

his stepchildren Kenneth

1958, he began his public

Callahan, Peter Callahan,

career as a staff psychiatrist

and Patrick Callahan.

and, later, as director at

we help people move.
Call for a free relocation portfolio
regarding your destination city.
Calll-800-688-1170 or go on-line
and visit our web site at

unborn children. When

rica, Sicily and Normandy.

HU. 'T REAL ESTATE ERA

Hopkins University of Public

monitor, he was also the first

becoming clinical professor

RELOCATION

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service p ortfolio in cludin g
• Nationally trained relocation experts
• Complete family needs analysis
• Global home sale assistance
• Special services for seniors
• Full community tour
• A complete cost of living analysis
• A list of all school systems
throughout WNY
• Complete spousal placement
assistance including resume
writing and corporate contacts
• 24 hour or less response time
• Confidentiality assured

In lieu of flowers,

Niagara County Mental

the family requests that

Health Services. In 1964,

contributions be made in

Governor Philip Hoff ap-

leopold's memory to the

pointed leopold as the first

UB School of Medicine and

Commissioner of Mental

Biomedical Sciences.
Hunt ERA Relocation Center
5570 Marn Street
Williamsville, NewYor1&lt; 14221-5410

48

l a ff al1 Plysitill

Wi11ter

2003

Email: huntrelocallon@huntrealestate.com

�Three i11tercowzected buildi11gs \\Jll make up the Buffalo L1fe Soences Complex on
the l3ut1alo- 1agara Medical Campus (l3NMC). 1()() acres bordered by Mam Street.

orth

Street. Michigan Avenue and Goodell Street. Pictured. abol'c /~ft, is the Umversity at But1alo
Center of Excellence in Bioinformatics, and, abtwc r('(ht, Roswell Park Cancer Institute's Center
for Genetics and Pharmacolot,'Y· A third building, headquarters for Hauptman-Woodward
Medical Research Insntute, not pictured. will be constructed to the left of the Ul3 building.
for more information on the BNMC. and \\·ork under way
in l3iomformaucs, see article on page 32.

,lt

the Ul3 Center of Excellence

�p H A R M A

c

p 0 E I A

0

LB ' 'HISTORY
Of

1EDICI ' E

( OLLEC.TIO

PRESF

TS

PHARMA C OPOEIA

This illustration was digitally reproduced from

offizinellen Cewachse, a
four - volume edition of
pharmaceutical plants
and their medicinal uses,
published in German in
r863. The pharmacopoeia by Otto Karl Berg
(1815-1866) is part of the
Robert L. Brown History
of Medicme Collection,
located in the Abbott Hall
Health Sciences Library.
Picture here is the

Apple, Pyrus malus, one
of a series of botanical

F

images digitally restored
as part of an initiative to
preserve and highlight

X

~

I
0-

1/

/
a

0

1'

unique resources from

a.(/

the library's collection.
Reproductions

c

are

available for purchase
through the library, and
can be viewed online at
i Media. buffalo. ed u/art/.
Image restoration was
performed by iMedia.

"

the instructwnal media

r

services department of
Computing and Infor mation Technology at the
University at Buffalo.

8POOO

Ol

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